locus-tag	class	description
J3K87_00010	COG0592	DNA-directed DNA polymerase activity
J3K87_00025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J3K87_00040	COG0616	signal peptide processing
J3K87_00055	COG3116	cell division
J3K87_00060	COG0768	penicillin binding
J3K87_00065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J3K87_00070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J3K87_00080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J3K87_00085	COG0772	Belongs to the SEDS family
J3K87_00090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J3K87_00095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J3K87_00100	COG1181	Belongs to the D-alanine--D-alanine ligase family
J3K87_00110	COG0849	cell division
J3K87_00115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J3K87_00120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J3K87_00125	COG0497	DNA recombination
J3K87_00130	COG4172	Belongs to the ABC transporter superfamily
J3K87_00135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J3K87_00140	COG0601	transmembrane transport
J3K87_00170	COG0012	GTP binding
J3K87_00175	COG2020	methyltransferase activity
J3K87_00185	COG3133	Outer membrane lipoprotein
J3K87_00190	COG3102	Protein conserved in bacteria
J3K87_00195	COG0018	arginyl-trna synthetase
J3K87_00210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J3K87_00215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J3K87_00220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J3K87_00225	COG0196	riboflavin kinase activity
J3K87_00230	COG3172	ATPase kinase involved in NAD metabolism
J3K87_00235	COG2129	metallophosphoesterase
J3K87_00240	COG0745	RESPONSE REGULATOR receiver
J3K87_00250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J3K87_00255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J3K87_00260	COG1217	gtp-binding protein TYPA
J3K87_00265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J3K87_00270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J3K87_00275	COG1561	YicC-like family, N-terminal region
J3K87_00280	COG0354	folic acid binding
J3K87_00285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J3K87_00290	COG2197	response regulator
J3K87_00300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J3K87_00340	COG0747	negative chemotaxis
J3K87_00345	COG0601	transmembrane transport
J3K87_00350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J3K87_00355	COG0444	Belongs to the ABC transporter superfamily
J3K87_00360	COG4608	Belongs to the ABC transporter superfamily
J3K87_00375	COG0251	oxidation-reduction process
J3K87_00380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J3K87_00385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J3K87_00390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J3K87_00395	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J3K87_00400	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J3K87_00405	COG0848	biopolymer transport protein
J3K87_00410	COG0811	peptide transport
J3K87_00415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J3K87_00420	COG3118	belongs to the thioredoxin family
J3K87_00425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J3K87_00425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_00425	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
J3K87_00430	COG1461	Dihydroxyacetone kinase
J3K87_00435	COG2376	Dihydroxyacetone kinase
J3K87_00440	COG0492	ferredoxin-NADP+ reductase activity
J3K87_00450	COG3753	Protein conserved in bacteria
J3K87_00470	COG3030	protein affecting phage T7 exclusion by the F plasmid
J3K87_00475	COG0006	proline dipeptidase activity
J3K87_00485	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
J3K87_00505	COG0129	dihydroxy-acid dehydratase activity
J3K87_00510	COG3978	acetolactate synthase activity
J3K87_00525	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J3K87_00530	COG0437	4 iron, 4 sulfur cluster binding
J3K87_00535	COG3301	Polysulphide reductase, NrfD
J3K87_00555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3K87_00560	COG1414	Transcriptional regulator
J3K87_00565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J3K87_00590	COG3068	Protein conserved in bacteria
J3K87_00615	COG1278	Cold shock
J3K87_00620	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J3K87_00625	COG0793	Belongs to the peptidase S41A family
J3K87_00630	COG2989	Protein conserved in bacteria
J3K87_00635	COG3108	Peptidase M15
J3K87_00640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3K87_00655	COG0537	adenosine 5'-monophosphoramidase activity
J3K87_00660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J3K87_00665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J3K87_00675	COG1162	GTPase activity
J3K87_00680	COG0583	DNA-binding transcription factor activity
J3K87_00685	COG1011	Hydrolase
J3K87_00690	COG0583	DNA-binding transcription factor activity
J3K87_00700	COG0252	asparaginase activity
J3K87_00710	COG5413	integral membrane protein
J3K87_00725	COG3835	regulator
J3K87_00730	COG2610	gluconate transmembrane transporter activity
J3K87_00735	COG1929	Belongs to the glycerate kinase type-1 family
J3K87_00740	COG1254	Belongs to the acylphosphatase family
J3K87_00745	COG3593	DNA synthesis involved in DNA repair
J3K87_00750	COG1611	Belongs to the LOG family
J3K87_00755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J3K87_00765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J3K87_00770	COG0316	Belongs to the HesB IscA family
J3K87_00770	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J3K87_00775	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_00780	COG1805	sodium ion transport
J3K87_00785	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_00790	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_00795	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_00800	COG2871	sodium ion transport
J3K87_00805	COG1477	protein flavinylation
J3K87_00810	COG2991	Protein conserved in bacteria
J3K87_00815	COG0482	sulfurtransferase activity
J3K87_00820	COG2814	Major facilitator Superfamily
J3K87_00825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J3K87_00830	COG2974	May be involved in recombination
J3K87_00855	COG4657	Part of a membrane complex involved in electron transport
J3K87_00860	COG2878	Part of a membrane complex involved in electron transport
J3K87_00865	COG4656	Part of a membrane complex involved in electron transport
J3K87_00890	COG1560	Kdo2-lipid A biosynthetic process
J3K87_00895	COG0402	S-adenosylhomocysteine deaminase activity
J3K87_00900	COG4143	(ABC) transporter
J3K87_00905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J3K87_00910	COG0617	tRNA 3'-terminal CCA addition
J3K87_00915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J3K87_00925	COG2911	Protein conserved in bacteria
J3K87_00935	COG0346	lactoylglutathione lyase activity
J3K87_00940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J3K87_00950	COG0287	Prephenate dehydrogenase
J3K87_00950	COG1605	Chorismate mutase
J3K87_00955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J3K87_00960	COG0859	PFAM glycosyl transferase family 9
J3K87_00965	COG0469	pyruvate kinase activity
J3K87_00970	COG2062	phosphohistidine phosphatase, SixA
J3K87_00975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J3K87_00980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J3K87_00985	COG0733	neurotransmitter:sodium symporter activity
J3K87_00990	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J3K87_00995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J3K87_01000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J3K87_01005	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J3K87_01010	COG4972	Pilus assembly protein
J3K87_01030	COG4796	Type ii and iii secretion system protein
J3K87_01035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J3K87_01040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J3K87_01045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J3K87_01050	COG1280	lysine exporter protein (LysE YggA)
J3K87_01055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J3K87_01065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J3K87_01080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J3K87_01135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J3K87_01140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J3K87_01145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J3K87_01165	COG1253	flavin adenine dinucleotide binding
J3K87_01170	COG0564	pseudouridine synthase activity
J3K87_01175	COG0406	alpha-ribazole phosphatase activity
J3K87_01180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J3K87_01185	COG1678	Uncharacterized ACR, COG1678
J3K87_01190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J3K87_01200	COG0271	Belongs to the BolA IbaG family
J3K87_01225	COG0653	protein targeting
J3K87_01235	COG0494	nUDIX hydrolase
J3K87_01240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J3K87_01250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J3K87_01265	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J3K87_01270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J3K87_01275	COG0083	homoserine kinase activity
J3K87_01280	COG0460	homoserine dehydrogenase
J3K87_01280	COG0527	aspartate kinase activity
J3K87_01285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J3K87_01290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J3K87_01295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J3K87_01325	COG2195	Cleaves the N-terminal amino acid of tripeptides
J3K87_01330	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J3K87_01335	COG0194	GDP metabolic process
J3K87_01340	COG1538	Outer membrane efflux protein
J3K87_01345	COG2914	Belongs to the UPF0125 (RnfH) family
J3K87_01350	COG2867	negative regulation of translational initiation
J3K87_01355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J3K87_01360	COG4149	molybdate abc transporter
J3K87_01365	COG0725	ABC transporter, periplasmic molybdate-binding protein
J3K87_01370	COG0842	Transport permease protein
J3K87_01375	COG1131	(ABC) transporter
J3K87_01380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J3K87_01385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J3K87_01400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J3K87_01405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J3K87_01410	COG1121	(ABC) transporter
J3K87_01420	COG2920	part of a sulfur-relay system
J3K87_01425	COG0670	Belongs to the BI1 family
J3K87_01430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J3K87_01445	COG0084	hydrolase, TatD family'
J3K87_01450	COG0210	DNA helicase
J3K87_01455	COG3842	ATPase activity
J3K87_01460	COG1176	ABC-type spermidine putrescine transport system, permease component I
J3K87_01465	COG1177	transmembrane transport
J3K87_01470	COG0632	four-way junction helicase activity
J3K87_01475	COG2255	four-way junction helicase activity
J3K87_01480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J3K87_01485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J3K87_01525	COG0488	(ABC) transporter
J3K87_01530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J3K87_01540	COG1271	oxidase subunit
J3K87_01545	COG1294	oxidase, subunit
J3K87_01560	COG0824	Thioesterase
J3K87_01565	COG0811	peptide transport
J3K87_01570	COG0848	biopolymer transport protein
J3K87_01575	COG3064	Membrane
J3K87_01575	COG3064	Membrane
J3K87_01580	COG0823	Involved in the tonB-independent uptake of proteins
J3K87_01595	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J3K87_01600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J3K87_01610	COG0488	(ABC) transporter
J3K87_01620	COG0303	'Molybdopterin
J3K87_01625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J3K87_01635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J3K87_01640	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J3K87_01650	COG0564	pseudouridine synthase activity
J3K87_01655	COG3023	N-Acetylmuramoyl-L-alanine amidase
J3K87_01660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J3K87_01665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J3K87_01670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J3K87_01675	COG0626	cystathionine gamma-synthase activity
J3K87_01680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J3K87_01695	COG1702	phosphate starvation-inducible protein PhoH
J3K87_01720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J3K87_01740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J3K87_01745	COG1660	Displays ATPase and GTPase activities
J3K87_01750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_01755	COG1137	ATPase activity
J3K87_01760	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J3K87_01770	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J3K87_01775	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J3K87_01785	COG1704	LemA family
J3K87_01790	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J3K87_01790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J3K87_01790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J3K87_01795	COG1105	Belongs to the carbohydrate kinase PfkB family
J3K87_01800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_01800	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_01810	COG1523	belongs to the glycosyl hydrolase 13 family
J3K87_01815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J3K87_01820	COG0297	glycogen (starch) synthase activity
J3K87_01825	COG0058	SHG alpha-glucan phosphorylase activity
J3K87_01855	COG1187	pseudouridine synthase activity
J3K87_01860	COG2814	Major facilitator Superfamily
J3K87_01870	COG3381	protein complex oligomerization
J3K87_01880	COG0791	NLP P60 protein
J3K87_01885	COG2932	Transcriptional regulator
J3K87_01890	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J3K87_01895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J3K87_01900	COG2990	Protein conserved in bacteria
J3K87_01910	COG1643	Atp-dependent helicase
J3K87_01915	COG2707	UPF0756 membrane protein
J3K87_01920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J3K87_01925	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J3K87_01930	COG0534	Mate efflux family protein
J3K87_01935	COG1074	ATP-dependent DNA helicase activity
J3K87_01940	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J3K87_01945	COG4535	Mg2 and Co2 transporter CorC
J3K87_01955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J3K87_01960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J3K87_01965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J3K87_01970	COG2271	Major facilitator Superfamily
J3K87_01975	COG0584	glycerophosphoryl diester phosphodiesterase
J3K87_01980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J3K87_01985	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
J3K87_01990	COG0247	lactate metabolic process
J3K87_02020	COG0517	IMP dehydrogenase activity
J3K87_02020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J3K87_02030	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
J3K87_02035	COG0385	Bile acid
J3K87_02040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_02045	COG0561	phosphatase activity
J3K87_02055	COG1595	DNA-templated transcription, initiation
J3K87_02060	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
J3K87_02070	COG0318	PFAM AMP-dependent synthetase and ligase
J3K87_02075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J3K87_02085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J3K87_02090	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J3K87_02095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J3K87_02095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J3K87_02110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J3K87_02120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3K87_02125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J3K87_02130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3K87_02145	COG0750	zinc metalloprotease
J3K87_02150	COG0575	Belongs to the CDS family
J3K87_02155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J3K87_02160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3K87_02170	COG0671	phosphoesterase, PA-phosphatase related
J3K87_02175	COG1534	Rna-binding protein
J3K87_02180	COG0463	Glycosyl transferase, family 2
J3K87_02185	COG1686	Belongs to the peptidase S11 family
J3K87_02190	COG0859	PFAM glycosyl transferase family 9
J3K87_02200	COG0328	RNA-DNA hybrid ribonuclease activity
J3K87_02205	COG1286	toxin biosynthetic process
J3K87_02210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J3K87_02220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J3K87_02225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J3K87_02235	COG0251	oxidation-reduction process
J3K87_02240	COG1496	oxidoreductase activity
J3K87_02250	COG0582	viral genome integration into host DNA
J3K87_02375	COG0582	viral genome integration into host DNA
J3K87_02430	COG0556	nucleotide-excision repair
J3K87_02445	COG3179	chitinase
J3K87_02460	COG3728	DNA packaging
J3K87_02580	COG5645	(Lipo)protein
J3K87_02595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J3K87_02605	COG1792	Involved in formation and maintenance of cell shape
J3K87_02610	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J3K87_02615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J3K87_02620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J3K87_02625	COG0121	glutamine amidotransferase
J3K87_02630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J3K87_02635	COG2949	membrane
J3K87_02645	COG1556	Lactate utilization protein
J3K87_02650	COG1139	Iron-sulfur cluster binding protein
J3K87_02655	COG0247	lactate metabolic process
J3K87_02660	COG1620	l-lactate permease
J3K87_02665	COG2916	Histone family protein nucleoid-structuring protein H-NS
J3K87_02670	COG1757	Na H antiporter
J3K87_02675	COG1879	ABC-type sugar transport system periplasmic component
J3K87_02680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J3K87_02690	COG2990	Protein conserved in bacteria
J3K87_02695	COG0508	dehydrogenase complex catalyzes the overall conversion of
J3K87_02700	COG0567	Dehydrogenase, E1 component
J3K87_02705	COG1121	(ABC) transporter
J3K87_02710	COG0739	heme binding
J3K87_02715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J3K87_02720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J3K87_02730	COG0561	phosphatase activity
J3K87_02735	COG3850	Histidine kinase
J3K87_02745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J3K87_02755	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J3K87_02765	COG4221	oxidoreductase activity
J3K87_02770	COG0133	tryptophan synthase activity
J3K87_02775	COG0159	tryptophan synthase activity
J3K87_02790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J3K87_02790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J3K87_02805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J3K87_02810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J3K87_02835	COG0640	Transcriptional regulator
J3K87_02845	COG0189	ligase activity
J3K87_02850	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J3K87_02855	COG0281	malic enzyme
J3K87_02855	COG0280	phosphate acetyltransferase
J3K87_02870	COG3683	transport system, periplasmic component
J3K87_02875	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
J3K87_02880	COG1115	amino acid carrier protein
J3K87_02885	COG1116	anion transmembrane transporter activity
J3K87_02890	COG1116	anion transmembrane transporter activity
J3K87_02895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J3K87_02900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J3K87_02905	COG2104	thiamine diphosphate biosynthetic process
J3K87_02910	COG2022	thiamine diphosphate biosynthetic process
J3K87_02915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J3K87_02920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J3K87_02930	COG0351	phosphomethylpyrimidine kinase
J3K87_02940	COG0481	GTPase activity
J3K87_02945	COG0681	Belongs to the peptidase S26 family
J3K87_02955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J3K87_02970	COG2826	transposase and inactivated derivatives, IS30 family
J3K87_02975	COG1840	ABC-type Fe3 transport system, periplasmic component
J3K87_03005	COG2194	sulfuric ester hydrolase activity
J3K87_03010	COG0528	UMP kinase activity
J3K87_03015	COG0233	cytoplasmic translational termination
J3K87_03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J3K87_03025	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
J3K87_03030	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J3K87_03035	COG0590	tRNA wobble adenosine to inosine editing
J3K87_03040	COG0513	Belongs to the DEAD box helicase family
J3K87_03045	COG4785	May be involved in cell division
J3K87_03050	COG1185	polyribonucleotide nucleotidyltransferase activity
J3K87_03055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J3K87_03065	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J3K87_03080	COG3083	sulfuric ester hydrolase activity
J3K87_03090	COG1309	transcriptional regulator
J3K87_03095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_03100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3K87_03115	COG3955	Domain of unknown function (DUF1919)
J3K87_03120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J3K87_03135	COG0517	IMP dehydrogenase activity
J3K87_03135	COG0516	GMP reductase activity
J3K87_03140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J3K87_03145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J3K87_03150	COG0814	amino acid
J3K87_03155	COG0814	amino acid
J3K87_03165	COG3105	Protein conserved in bacteria
J3K87_03170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J3K87_03195	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J3K87_03200	COG1823	symporter activity
J3K87_03205	COG0778	Nitroreductase
J3K87_03215	COG0072	phenylalanine-tRNA ligase activity
J3K87_03220	COG0776	regulation of translation
J3K87_03225	COG0791	NLP P60 protein
J3K87_03235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J3K87_03240	COG1940	carbohydrate kinase activity
J3K87_03240	COG1846	Transcriptional regulator
J3K87_03245	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J3K87_03250	COG1522	sequence-specific DNA binding
J3K87_03255	COG1674	ftsk spoiiie
J3K87_03260	COG2321	neutral zinc metallopeptidase
J3K87_03265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J3K87_03270	COG1214	PFAM Peptidase M22, glycoprotease
J3K87_03275	COG1435	thymidine kinase activity
J3K87_03280	COG3074	FtsZ-dependent cytokinesis
J3K87_03285	COG1494	fructose-1,6-bisphosphatase
J3K87_03290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J3K87_03295	COG1136	(ABC) transporter
J3K87_03295	COG0577	efflux transmembrane transporter activity
J3K87_03300	COG2205	protein histidine kinase activity
J3K87_03305	COG0745	RESPONSE REGULATOR receiver
J3K87_03310	COG3956	TIGRFAM MazG family protein
J3K87_03320	COG0285	dihydrofolate synthase activity
J3K87_03330	COG0779	Required for maturation of 30S ribosomal subunits
J3K87_03335	COG0195	Participates in both transcription termination and antitermination
J3K87_03340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J3K87_03345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J3K87_03350	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J3K87_03355	COG2951	lytic endotransglycosylase activity
J3K87_03365	COG0857	belongs to the CobB CobQ family
J3K87_03365	COG0280	phosphate acetyltransferase
J3K87_03375	COG0737	Belongs to the 5'-nucleotidase family
J3K87_03395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J3K87_03405	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J3K87_03415	COG0589	response to stress
J3K87_03425	COG2969	positive regulation of protein catabolic process
J3K87_03430	COG0625	glutathione transferase activity
J3K87_03435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J3K87_03445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J3K87_03450	COG1448	Aminotransferase
J3K87_03455	COG0006	proline dipeptidase activity
J3K87_03485	COG1487	ribonuclease activity
J3K87_03500	COG0556	nucleotide-excision repair
J3K87_03505	COG2822	iron ion transport
J3K87_03510	COG2837	iron assimilation
J3K87_03520	COG0613	PHP domain protein
J3K87_03530	COG2925	Exonuclease
J3K87_03535	COG0038	chloride channel
J3K87_03545	COG1509	lysine 2,3-aminomutase activity
J3K87_03555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J3K87_03560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J3K87_03570	COG2814	Major facilitator Superfamily
J3K87_03575	COG0741	lytic transglycosylase activity
J3K87_03580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J3K87_03585	COG0626	cystathionine gamma-synthase activity
J3K87_03610	COG2363	Small membrane protein
J3K87_03615	COG0277	FAD linked oxidase domain protein
J3K87_03620	COG0243	molybdopterin cofactor binding
J3K87_03625	COG3005	denitrification pathway
J3K87_03635	COG0315	cyclic pyranopterin monophosphate synthase activity
J3K87_03640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J3K87_03645	COG0314	molybdopterin synthase activity
J3K87_03650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J3K87_03655	COG1444	tRNA N-acetyltransferase activity
J3K87_03665	COG0583	DNA-binding transcription factor activity
J3K87_03690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J3K87_03695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J3K87_03710	COG1737	Transcriptional regulator
J3K87_03715	COG2731	YhcH YjgK YiaL family protein
J3K87_03720	COG0248	Ppx GppA phosphatase
J3K87_03725	COG2926	Belongs to the UPF0265 family
J3K87_03730	COG0527	aspartate kinase activity
J3K87_03735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J3K87_03740	COG3100	YcgL domain-containing protein
J3K87_03745	COG0305	Participates in initiation and elongation during chromosome replication
J3K87_03750	COG4607	ABC-type enterochelin transport system periplasmic component
J3K87_03755	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J3K87_03760	COG4605	iron ion homeostasis
J3K87_03765	COG4604	ABC transporter, ATP-binding protein
J3K87_03770	COG1392	Phosphate transport regulator
J3K87_03775	COG0306	phosphate transporter
J3K87_03780	COG4991	sh3 domain protein
J3K87_03790	COG3945	hemerythrin HHE cation binding domain
J3K87_03805	COG1278	Cold shock
J3K87_03810	COG0288	reversible hydration of carbon dioxide
J3K87_03815	COG0028	Belongs to the TPP enzyme family
J3K87_03820	COG0440	acetolactate synthase activity
J3K87_03825	COG0312	modulator of DNA gyrase
J3K87_03830	COG3028	Belongs to the UPF0307 family
J3K87_03835	COG3094	Invasion gene expression up-regulator, SirB
J3K87_03845	COG1811	Na channel or pump
J3K87_03850	COG3787	Belongs to the UPF0306 family
J3K87_03855	COG0023	Translation Initiation Factor
J3K87_03860	COG0284	orotidine-5'-phosphate decarboxylase activity
J3K87_03865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J3K87_03870	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J3K87_03875	COG0776	regulation of translation
J3K87_03880	COG0539	negative regulation of cytoplasmic translation
J3K87_03890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3K87_03900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J3K87_03910	COG1785	Belongs to the alkaline phosphatase family
J3K87_03915	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
J3K87_03925	COG3264	Mechanosensitive ion channel
J3K87_03925	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J3K87_03930	COG3264	Mechanosensitive ion channel
J3K87_03930	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J3K87_03935	COG0318	PFAM AMP-dependent synthetase and ligase
J3K87_03940	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J3K87_03945	COG0596	Alpha beta hydrolase
J3K87_03955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J3K87_03975	COG1380	Effector of murein hydrolase LrgA
J3K87_03980	COG1346	cytolysis
J3K87_03995	COG3036	rescue of stalled ribosome
J3K87_04000	COG2226	methyltransferase
J3K87_04020	COG0658	competence protein
J3K87_04020	COG2333	competence protein COMEC
J3K87_04025	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J3K87_04030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J3K87_04035	COG0737	Belongs to the 5'-nucleotidase family
J3K87_04060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J3K87_04065	COG0508	dehydrogenase complex catalyzes the overall conversion of
J3K87_04070	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J3K87_04080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J3K87_04095	COG1132	(ABC) transporter
J3K87_04100	COG1346	cytolysis
J3K87_04110	COG1199	ATP-dependent helicase activity
J3K87_04120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J3K87_04125	COG0629	single-stranded DNA binding
J3K87_04160	COG2070	2-Nitropropane dioxygenase
J3K87_04175	COG2315	Protein conserved in bacteria
J3K87_04180	COG4172	Belongs to the ABC transporter superfamily
J3K87_04185	COG4171	peptide transport system, permease
J3K87_04190	COG4168	peptide transport system, permease
J3K87_04195	COG4166	transmembrane transport
J3K87_04200	COG3283	Transcriptional regulator of aromatic amino acids metabolism
J3K87_04205	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J3K87_04210	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J3K87_04215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J3K87_04225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J3K87_04235	COG1368	sulfuric ester hydrolase activity
J3K87_04240	COG3217	Mosc domain protein beta barrel domain protein
J3K87_04240	COG0633	Ferredoxin
J3K87_04245	COG1722	exodeoxyribonuclease VII activity
J3K87_04250	COG0142	geranyltranstransferase activity
J3K87_04260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J3K87_04265	COG1530	ribonuclease E activity
J3K87_04270	COG1944	ATP diphosphatase activity
J3K87_04285	COG0500	methyltransferase
J3K87_04295	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J3K87_04350	COG2826	transposase and inactivated derivatives, IS30 family
J3K87_04415	COG4104	PAAR repeat-containing protein
J3K87_04415	COG3209	COG3209 Rhs family protein
J3K87_04420	COG4104	PAAR repeat-containing protein
J3K87_04420	COG3209	COG3209 Rhs family protein
J3K87_04430	COG0583	DNA-binding transcription factor activity
J3K87_04435	COG0786	glutamate:sodium symporter activity
J3K87_04450	COG0640	Transcriptional regulator
J3K87_04530	COG2351	hydroxyisourate hydrolase activity
J3K87_04540	COG0586	Pfam SNARE associated Golgi protein
J3K87_04545	COG0187	DNA topoisomerase II activity
J3K87_04555	COG1349	DNA-binding transcription factor activity
J3K87_04560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J3K87_04570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J3K87_04575	COG4988	ABC transporter
J3K87_04580	COG2911	Protein conserved in bacteria
J3K87_04585	COG0729	surface antigen
J3K87_04590	COG2861	carbohydrate metabolic process
J3K87_04595	COG4942	peptidase
J3K87_04600	COG0588	phosphoglycerate mutase activity
J3K87_04610	COG0572	uridine kinase
J3K87_04615	COG0717	Belongs to the dCTP deaminase family
J3K87_04620	COG1309	transcriptional regulator
J3K87_04625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_04630	COG1129	ABC transporter
J3K87_04630	COG0842	Transport permease protein
J3K87_04635	COG0842	Transport permease protein
J3K87_04645	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J3K87_04650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J3K87_04655	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J3K87_04675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J3K87_04680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J3K87_04690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3K87_04695	COG4166	transmembrane transport
J3K87_04705	COG0444	Belongs to the ABC transporter superfamily
J3K87_04710	COG4608	Belongs to the ABC transporter superfamily
J3K87_04720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J3K87_04730	COG0747	negative chemotaxis
J3K87_04735	COG0814	amino acid
J3K87_04740	COG1760	l-serine dehydratase
J3K87_04750	COG0135	phosphoribosylanthranilate isomerase activity
J3K87_04750	COG0134	indole-3-glycerol-phosphate synthase activity
J3K87_04755	COG3177	Filamentation induced by cAMP protein fic
J3K87_04760	COG3098	single-species biofilm formation
J3K87_04765	COG0564	pseudouridine synthase activity
J3K87_04770	COG3140	Belongs to the UPF0181 family
J3K87_04780	COG3025	triphosphatase activity
J3K87_04785	COG3106	COG3106 Predicted ATPase
J3K87_04790	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J3K87_04800	COG1473	amidohydrolase
J3K87_04805	COG3069	C4-dicarboxylate transmembrane transporter activity
J3K87_04815	COG0495	leucyl-tRNA aminoacylation
J3K87_04820	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J3K87_04825	COG1466	dna polymerase III delta subunit
J3K87_04830	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J3K87_04835	COG0237	dephospho-CoA kinase activity
J3K87_04845	COG1459	type II secretion system
J3K87_04850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3K87_04855	COG4969	Belongs to the N-Me-Phe pilin family
J3K87_04860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J3K87_04870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J3K87_04875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J3K87_04880	COG0730	response to heat
J3K87_04885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J3K87_04890	COG0183	Belongs to the thiolase family
J3K87_04895	COG1250	3-hydroxyacyl-CoA dehydrogenase
J3K87_04895	COG1024	Enoyl-CoA hydratase
J3K87_04910	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J3K87_04915	COG3383	formate dehydrogenase (NAD+) activity
J3K87_04915	COG0243	molybdopterin cofactor binding
J3K87_04920	COG0243	molybdopterin cofactor binding
J3K87_04920	COG3383	formate dehydrogenase (NAD+) activity
J3K87_04925	COG0437	4 iron, 4 sulfur cluster binding
J3K87_04930	COG2864	formate dehydrogenase
J3K87_04935	COG3058	Necessary for formate dehydrogenase activity
J3K87_04965	COG1560	Kdo2-lipid A biosynthetic process
J3K87_04970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J3K87_04980	COG0302	gtp cyclohydrolase
J3K87_04985	COG3642	lipopolysaccharide core region biosynthetic process
J3K87_04995	COG0110	maltose O-acetyltransferase activity
J3K87_05005	COG0583	DNA-binding transcription factor activity
J3K87_05025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J3K87_05030	COG0215	cysteine-tRNA ligase activity
J3K87_05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J3K87_05040	COG0617	tRNA 3'-terminal CCA addition
J3K87_05070	COG2975	iron-sulfur cluster assembly
J3K87_05075	COG0633	Ferredoxin
J3K87_05080	COG0443	Heat shock 70 kDa protein
J3K87_05095	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J3K87_05105	COG0822	iron-sulfur transferase activity
J3K87_05110	COG1104	cysteine desulfurase activity
J3K87_05115	COG1959	2 iron, 2 sulfur cluster binding
J3K87_05125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J3K87_05130	COG5002	protein histidine kinase activity
J3K87_05130	COG2198	Histidine kinase
J3K87_05130	COG0784	Response regulator, receiver
J3K87_05135	COG0697	spore germination
J3K87_05140	COG2840	Smr protein MutS2
J3K87_05145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J3K87_05150	COG2226	methyltransferase
J3K87_05155	COG2830	Protein of unknown function (DUF452)
J3K87_05160	COG0156	8-amino-7-oxononanoate synthase activity
J3K87_05165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J3K87_05175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J3K87_05180	COG2027	D-alanyl-D-alanine carboxypeptidase
J3K87_05200	COG2801	Transposase and inactivated derivatives
J3K87_05210	COG2856	Zn peptidase
J3K87_05215	COG3620	sequence-specific DNA binding
J3K87_05250	COG1444	tRNA N-acetyltransferase activity
J3K87_05255	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J3K87_05260	COG0138	bifunctional purine biosynthesis protein purh
J3K87_05265	COG2801	Transposase and inactivated derivatives
J3K87_05285	COG3210	domain, Protein
J3K87_05290	COG2831	hemolysin activation secretion protein
J3K87_05300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3K87_05310	COG3078	GTPase activator activity
J3K87_05320	COG0786	glutamate:sodium symporter activity
J3K87_05325	COG3112	Uncharacterised protein family (UPF0231)
J3K87_05335	COG2350	Protein conserved in bacteria
J3K87_05340	COG1607	acyl-coa hydrolase
J3K87_05355	COG3092	negative regulation of chromosome organization
J3K87_05365	COG2056	Na+-H+ antiporter family
J3K87_05370	COG0708	Exodeoxyribonuclease III
J3K87_05375	COG0583	DNA-binding transcription factor activity
J3K87_05395	COG0254	rRNA binding
J3K87_05410	COG0753	catalase activity
J3K87_05420	COG1408	metallophosphoesterase
J3K87_05425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J3K87_05430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J3K87_05435	COG1085	galactose-1-phosphate uridylyltransferase
J3K87_05445	COG2017	converts alpha-aldose to the beta-anomer
J3K87_05465	COG0489	protein tyrosine kinase activity
J3K87_05475	COG2095	MarC family integral membrane protein
J3K87_05480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J3K87_05490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J3K87_05495	COG2354	Protein conserved in bacteria
J3K87_05500	COG3071	HemY protein
J3K87_05505	COG2959	enzyme of heme biosynthesis
J3K87_05515	COG0181	hydroxymethylbilane synthase activity
J3K87_05520	COG1012	belongs to the aldehyde dehydrogenase family
J3K87_05520	COG1454	alcohol dehydrogenase
J3K87_05545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J3K87_05550	COG2364	Membrane
J3K87_05555	COG0800	Aldolase
J3K87_05560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J3K87_05565	COG1904	glucuronate isomerase
J3K87_05575	COG2186	Transcriptional regulator
J3K87_05585	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J3K87_05585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J3K87_05590	COG1216	Glycosyl transferase, family 2
J3K87_05595	COG1216	Glycosyl transferase, family 2
J3K87_05605	COG3306	glycosyltransferase involved in LPS biosynthesis
J3K87_05615	COG5039	Polysaccharide pyruvyl transferase
J3K87_05620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J3K87_05625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J3K87_05630	COG1605	Chorismate mutase
J3K87_05630	COG0077	Prephenate dehydratase
J3K87_05635	COG0339	signal peptide processing
J3K87_05640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J3K87_05645	COG1882	Formate acetyltransferase
J3K87_05650	COG2116	formate transmembrane transporter activity
J3K87_05655	COG1238	metal cluster binding
J3K87_05660	COG0501	Belongs to the peptidase M48B family
J3K87_05670	COG2431	L-lysine efflux transmembrane transporter activity
J3K87_05675	COG1169	isochorismate synthase
J3K87_05680	COG0436	Aminotransferase
J3K87_05685	COG2962	Rard protein
J3K87_05690	COG2962	Rard protein
J3K87_05695	COG1280	lysine exporter protein (LysE YggA)
J3K87_05700	COG4771	TonB-dependent receptor
J3K87_05700	COG1629	transport
J3K87_05705	COG0748	coenzyme F420 binding
J3K87_05715	COG4235	cytochrome complex assembly
J3K87_05715	COG3088	subunit of a heme lyase
J3K87_05720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J3K87_05725	COG1138	Cytochrome C-type biogenesis protein
J3K87_05730	COG0475	glutathione-regulated potassium exporter activity
J3K87_05730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J3K87_05740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J3K87_05750	COG3111	PFAM Bacterial OB fold (BOF) protein
J3K87_05765	COG0745	RESPONSE REGULATOR receiver
J3K87_05770	COG0642	Histidine kinase
J3K87_05775	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J3K87_05780	COG1862	Preprotein translocase
J3K87_05785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J3K87_05790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J3K87_05795	COG1528	Iron-storage protein
J3K87_05800	COG1528	Iron-storage protein
J3K87_05805	COG2252	PERMEase
J3K87_05810	COG0424	maF-like protein
J3K87_05820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J3K87_05820	COG0301	tRNA thio-modification
J3K87_05825	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J3K87_05830	COG0330	HflC and HflK could
J3K87_05835	COG0330	HflC and HflK could
J3K87_05840	COG3118	belongs to the thioredoxin family
J3K87_05860	COG0531	amino acid
J3K87_05865	COG0531	amino acid
J3K87_05880	COG3047	cAMP biosynthetic process
J3K87_05885	COG0542	response to heat
J3K87_05890	COG0798	PFAM Bile acid sodium symporter
J3K87_05895	COG1393	Belongs to the ArsC family
J3K87_05905	COG1027	Aspartate ammonia-lyase
J3K87_05915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J3K87_05920	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J3K87_05920	COG3064	Membrane
J3K87_05920	COG3583	domain protein
J3K87_05930	COG0720	synthase
J3K87_05935	COG0602	queuosine metabolic process
J3K87_05960	COG0795	lipopolysaccharide-transporting ATPase activity
J3K87_05965	COG0795	lipopolysaccharide-transporting ATPase activity
J3K87_05975	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J3K87_05985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J3K87_05995	COG0861	Integral membrane protein TerC family
J3K87_06015	COG1051	belongs to the nudix hydrolase family
J3K87_06020	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
J3K87_06030	COG1965	Belongs to the frataxin family
J3K87_06040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J3K87_06045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J3K87_06050	COG0564	pseudouridine synthase activity
J3K87_06060	COG0205	6-phosphofructokinase activity
J3K87_06065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J3K87_06070	COG1525	nuclease
J3K87_06075	COG1115	amino acid carrier protein
J3K87_06080	COG0628	permease
J3K87_06090	COG0826	peptidase U32
J3K87_06095	COG3307	-O-antigen
J3K87_06100	COG1519	Transferase
J3K87_06110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J3K87_06115	COG0802	atpase or kinase
J3K87_06120	COG1388	LysM domain
J3K87_06120	COG0860	N-Acetylmuramoyl-L-alanine amidase
J3K87_06130	COG2960	long-chain fatty acid transporting porin activity
J3K87_06155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J3K87_06165	COG0551	DNA topoisomerase type I activity
J3K87_06175	COG2137	regulation of response to DNA damage stimulus
J3K87_06180	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J3K87_06185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J3K87_06195	COG1322	Protein conserved in bacteria
J3K87_06200	COG0512	Glutamine amidotransferase of anthranilate synthase
J3K87_06210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J3K87_06215	COG0494	nUDIX hydrolase
J3K87_06220	COG0217	transcriptional regulatory protein
J3K87_06230	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J3K87_06235	COG0612	Peptidase, M16
J3K87_06240	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J3K87_06245	COG0471	metal ion transport
J3K87_06250	COG0583	DNA-binding transcription factor activity
J3K87_06255	COG3266	domain, Protein
J3K87_06260	COG1187	pseudouridine synthase activity
J3K87_06265	COG0009	L-threonylcarbamoyladenylate synthase
J3K87_06270	COG2837	iron assimilation
J3K87_06275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J3K87_06280	COG0512	Glutamine amidotransferase of anthranilate synthase
J3K87_06290	COG2226	methyltransferase
J3K87_06295	COG2268	Band 7 protein
J3K87_06300	COG2841	Protein conserved in bacteria
J3K87_06305	COG0359	binds to the 23S rRNA
J3K87_06315	COG2965	DNA replication, synthesis of RNA primer
J3K87_06330	COG3201	nicotinamide mononucleotide transporter
J3K87_06335	COG2976	Protein conserved in bacteria
J3K87_06345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J3K87_06350	COG1426	Protein conserved in bacteria
J3K87_06355	COG0659	secondary active sulfate transmembrane transporter activity
J3K87_06365	COG0673	inositol 2-dehydrogenase activity
J3K87_06370	COG0475	glutathione-regulated potassium exporter activity
J3K87_06370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J3K87_06395	COG2207	Transcriptional regulator
J3K87_06405	COG1902	pentaerythritol trinitrate reductase activity
J3K87_06410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J3K87_06415	COG2084	Dehydrogenase
J3K87_06420	COG0778	Nitroreductase
J3K87_06425	COG2095	MarC family integral membrane protein
J3K87_06440	COG0625	glutathione transferase activity
J3K87_06455	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J3K87_06460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J3K87_06475	COG1275	C4-dicarboxylate transporter malic acid transport protein
J3K87_06480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J3K87_06495	COG1132	(ABC) transporter
J3K87_06500	COG1854	S-ribosylhomocysteine lyase activity
J3K87_06505	COG3008	intermembrane lipid transfer
J3K87_06510	COG0735	belongs to the Fur family
J3K87_06515	COG0716	FMN binding
J3K87_06525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J3K87_06530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J3K87_06535	COG2252	PERMEase
J3K87_06540	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J3K87_06545	COG2081	HI0933 family
J3K87_06550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J3K87_06560	COG0560	Phosphoserine phosphatase
J3K87_06575	COG0058	SHG alpha-glucan phosphorylase activity
J3K87_06580	COG2909	trisaccharide binding
J3K87_06590	COG4580	involved in the transport of maltose and maltodextrins
J3K87_06595	COG3842	ATPase activity
J3K87_06610	COG3833	ABC-type maltose transport systems, permease component
J3K87_06615	COG1640	4-alpha-glucanotransferase
J3K87_06620	COG1966	Carbon starvation protein
J3K87_06625	COG0084	hydrolase, TatD family'
J3K87_06630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J3K87_06640	COG0778	Nitroreductase
J3K87_06655	COG4172	Belongs to the ABC transporter superfamily
J3K87_06660	COG0191	fructose-bisphosphate aldolase activity
J3K87_06665	COG0126	phosphoglycerate kinase activity
J3K87_06670	COG0471	metal ion transport
J3K87_06675	COG0471	metal ion transport
J3K87_06680	COG0471	metal ion transport
J3K87_06685	COG0187	DNA topoisomerase II activity
J3K87_06690	COG5002	protein histidine kinase activity
J3K87_06695	COG0745	RESPONSE REGULATOR receiver
J3K87_06720	COG0789	Transcriptional regulator
J3K87_06730	COG2217	Heavy metal translocating P-type atpase
J3K87_06740	COG0300	oxidoreductase activity
J3K87_06745	COG0778	Nitroreductase
J3K87_06750	COG0616	signal peptide processing
J3K87_06755	COG3719	Belongs to the RNase T2 family
J3K87_06765	COG1252	NADH dehydrogenase
J3K87_06770	COG2183	response to ionizing radiation
J3K87_06775	COG3063	Type IV pilus biogenesis stability protein PilW
J3K87_06815	COG2161	toxin-antitoxin pair type II binding
J3K87_06820	COG4115	mRNA cleavage
J3K87_06825	COG2835	tetraacyldisaccharide 4'-kinase activity
J3K87_06830	COG1663	tetraacyldisaccharide 4'-kinase activity
J3K87_06835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J3K87_06840	COG0740	serine-type endopeptidase activity
J3K87_06845	COG2166	iron-sulfur cluster assembly
J3K87_06865	COG0488	(ABC) transporter
J3K87_06870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J3K87_06885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J3K87_06890	COG5007	Belongs to the BolA IbaG family
J3K87_06900	COG2854	intermembrane phospholipid transfer
J3K87_06905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J3K87_06910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J3K87_06915	COG1127	ABC transporter
J3K87_06920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3K87_06925	COG1090	epimerase
J3K87_06945	COG0563	adenylate kinase activity
J3K87_06955	COG2814	Major facilitator Superfamily
J3K87_06985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J3K87_06995	COG1794	racemase activity, acting on amino acids and derivatives
J3K87_07000	COG2814	Major facilitator Superfamily
J3K87_07005	COG0363	glucosamine-6-phosphate deaminase activity
J3K87_07010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J3K87_07015	COG1218	3'(2'),5'-bisphosphate nucleotidase
J3K87_07020	COG0494	nUDIX hydrolase
J3K87_07025	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J3K87_07035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J3K87_07040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J3K87_07055	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J3K87_07060	COG1178	ABC-type Fe3 transport system permease component
J3K87_07065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_07070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J3K87_07075	COG2190	(PTS) system
J3K87_07085	COG0210	DNA helicase
J3K87_07090	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J3K87_07095	COG0409	Hydrogenase expression formation protein
J3K87_07100	COG0309	Hydrogenase expression formation protein (HypE)
J3K87_07125	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J3K87_07130	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
J3K87_07135	COG0437	4 iron, 4 sulfur cluster binding
J3K87_07140	COG5557	Pfam Polysulphide reductase, NrfD
J3K87_07145	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J3K87_07150	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J3K87_07155	COG1773	rubredoxin
J3K87_07160	COG0298	carbon dioxide binding
J3K87_07165	COG0375	protein maturation
J3K87_07200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J3K87_07205	COG0308	aminopeptidase N
J3K87_07210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J3K87_07215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J3K87_07220	COG0295	cytidine deaminase activity
J3K87_07225	COG2177	Part of the ABC transporter FtsEX involved in
J3K87_07230	COG2884	Cell division ATP-binding protein ftsE
J3K87_07235	COG0552	protein localization to endoplasmic reticulum
J3K87_07240	COG0742	ribosomal rna small subunit methyltransferase
J3K87_07245	COG3099	Belongs to the UPF0263 family
J3K87_07250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J3K87_07260	COG4160	amino acid transport
J3K87_07265	COG4215	(ABC) transporter
J3K87_07270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3K87_07275	COG1126	abc transporter atp-binding protein
J3K87_07280	COG1881	PFAM PEBP family protein
J3K87_07290	COG3620	sequence-specific DNA binding
J3K87_07300	COG4232	protein-disulfide reductase activity
J3K87_07305	COG3101	peptidyl-lysine hydroxylation
J3K87_07315	COG3107	peptidoglycan biosynthetic process
J3K87_07320	COG0792	nuclease activity
J3K87_07325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J3K87_07360	COG1138	Cytochrome C-type biogenesis protein
J3K87_07370	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J3K87_07375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J3K87_07380	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J3K87_07385	COG4133	protoheme IX ABC transporter activity
J3K87_07390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J3K87_07420	COG3630	sodium ion export across plasma membrane
J3K87_07430	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J3K87_07435	COG2824	Alkylphosphonate utilization operon protein PhnA
J3K87_07440	COG1858	cytochrome C peroxidase
J3K87_07450	COG0762	integral membrane protein
J3K87_07455	COG3171	Protein conserved in bacteria
J3K87_07460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J3K87_07465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3K87_07470	COG0416	fatty acid biosynthetic process
J3K87_07475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J3K87_07480	COG1399	metal-binding, possibly nucleic acid-binding protein
J3K87_07485	COG4137	Cytochrome C assembly protein
J3K87_07490	COG4536	flavin adenine dinucleotide binding
J3K87_07495	COG0733	neurotransmitter:sodium symporter activity
J3K87_07505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_07505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J3K87_07510	COG3715	PTS system
J3K87_07515	COG3716	PTS system mannose fructose sorbose family IID component
J3K87_07550	COG1840	ABC-type Fe3 transport system, periplasmic component
J3K87_07565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J3K87_07580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J3K87_07585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J3K87_07590	COG0049	tRNA binding
J3K87_07595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J3K87_07600	COG0859	PFAM glycosyl transferase family 9
J3K87_07605	COG0859	PFAM glycosyl transferase family 9
J3K87_07615	COG3266	domain, Protein
J3K87_07615	COG3061	Opacity-associated protein A
J3K87_07620	COG1555	photosystem II stabilization
J3K87_07645	COG0732	type I restriction modification DNA specificity domain
J3K87_07650	COG4974	Belongs to the 'phage' integrase family
J3K87_07660	COG1181	Belongs to the D-alanine--D-alanine ligase family
J3K87_07660	COG2918	glutathione biosynthetic process
J3K87_07670	COG0814	amino acid
J3K87_07675	COG3691	Protein conserved in bacteria
J3K87_07680	COG4989	oxidoreductase activity
J3K87_07685	COG1022	Amp-dependent synthetase and ligase
J3K87_07710	COG4211	Belongs to the binding-protein-dependent transport system permease family
J3K87_07715	COG1129	ABC transporter
J3K87_07720	COG1879	ABC-type sugar transport system periplasmic component
J3K87_07725	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J3K87_07725	COG2885	chlorophyll binding
J3K87_07730	COG0277	FAD linked oxidase domain protein
J3K87_07730	COG0247	lactate metabolic process
J3K87_07735	COG2050	protein possibly involved in aromatic compounds catabolism
J3K87_07745	COG3005	denitrification pathway
J3K87_07750	COG3043	anaerobic respiration
J3K87_07755	COG0348	domain, Protein
J3K87_07760	COG0437	4 iron, 4 sulfur cluster binding
J3K87_07765	COG0243	molybdopterin cofactor binding
J3K87_07775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J3K87_07780	COG2249	NAD(P)H dehydrogenase (quinone) activity
J3K87_07795	COG1530	ribonuclease E activity
J3K87_07805	COG1755	Isoprenylcysteine carboxyl methyltransferase
J3K87_07815	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J3K87_07825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J3K87_07825	COG0678	peroxiredoxin activity
J3K87_07830	COG0583	DNA-binding transcription factor activity
J3K87_07835	COG1309	transcriptional regulator
J3K87_07840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J3K87_07845	COG0557	exoribonuclease II activity
J3K87_07855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J3K87_07860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J3K87_07870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J3K87_07890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J3K87_07895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J3K87_07900	COG0562	UDP-galactopyranose mutase
J3K87_07905	COG2244	polysaccharide biosynthetic process
J3K87_07915	COG0438	transferase activity, transferring glycosyl groups
J3K87_07925	COG0438	transferase activity, transferring glycosyl groups
J3K87_07935	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
J3K87_07945	COG1575	Belongs to the MenA family. Type 1 subfamily
J3K87_07950	COG4804	nuclease activity
J3K87_07955	COG1720	tRNA m6t6A37 methyltransferase activity
J3K87_07965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J3K87_07985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J3K87_07990	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J3K87_07995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J3K87_08020	COG0825	malonyl-CoA metabolic process
J3K87_08030	COG0204	Acyl-transferase
J3K87_08035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J3K87_08060	COG0783	Belongs to the Dps family
J3K87_08075	COG1289	transmembrane transporter activity
J3K87_08080	COG1803	Methylglyoxal synthase
J3K87_08085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J3K87_08110	COG2153	protein acetylation
J3K87_08115	COG2927	DNA polymerase III (CHI subunit)
J3K87_08120	COG1652	LysM domain
J3K87_08125	COG0544	peptidyl-prolyl cis-trans isomerase activity
J3K87_08130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J3K87_08145	COG1045	serine acetyltransferase
J3K87_08150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J3K87_08180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J3K87_08195	COG0521	Mo-molybdopterin cofactor biosynthetic process
J3K87_08205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J3K87_08215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J3K87_08230	COG0625	glutathione transferase activity
J3K87_08235	COG0019	diaminopimelate decarboxylase activity
J3K87_08245	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J3K87_08250	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J3K87_08255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J3K87_08260	COG1053	succinate dehydrogenase
J3K87_08265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J3K87_08275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J3K87_08280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J3K87_08295	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J3K87_08300	COG2264	protein methyltransferase activity
J3K87_08320	COG0037	tRNA processing
J3K87_08330	COG4974	Belongs to the 'phage' integrase family
J3K87_08385	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J3K87_08400	COG1151	hydroxylamine reductase activity
J3K87_08405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J3K87_08410	COG2244	polysaccharide biosynthetic process
J3K87_08415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J3K87_08425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J3K87_08430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J3K87_08435	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
J3K87_08455	COG0728	peptidoglycan biosynthetic process
J3K87_08460	COG0268	Binds directly to 16S ribosomal RNA
J3K87_08465	COG0569	domain protein
J3K87_08470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J3K87_08475	COG3276	selenocysteine insertion sequence binding
J3K87_08480	COG1921	L-seryl-tRNASec selenium transferase activity
J3K87_08490	COG0716	FMN binding
J3K87_08510	COG4771	TonB-dependent receptor
J3K87_08510	COG1629	transport
J3K87_08535	COG2431	L-lysine efflux transmembrane transporter activity
J3K87_08550	COG3545	Serine hydrolase
J3K87_08570	COG2826	transposase and inactivated derivatives, IS30 family
J3K87_08580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J3K87_08580	COG1215	transferase activity, transferring glycosyl groups
J3K87_08610	COG1119	ATPase activity
J3K87_08625	COG1739	Uncharacterized protein family UPF0029
J3K87_08630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J3K87_08635	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
J3K87_08640	COG1970	mechanosensitive ion channel activity
J3K87_08650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J3K87_08655	COG0321	lipoyl(octanoyl) transferase activity
J3K87_08660	COG2921	Belongs to the UPF0250 family
J3K87_08665	COG1686	Belongs to the peptidase S11 family
J3K87_08670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J3K87_08675	COG0772	Belongs to the SEDS family
J3K87_08680	COG0768	penicillin binding
J3K87_08685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J3K87_08690	COG0799	negative regulation of ribosome biogenesis
J3K87_08700	COG1126	abc transporter atp-binding protein
J3K87_08715	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
J3K87_08725	COG3691	Protein conserved in bacteria
J3K87_08770	COG0832	Belongs to the urease beta subunit family
J3K87_08775	COG0831	urea catabolic process
J3K87_08785	COG1122	ATPase activity
J3K87_08795	COG0310	cobalt ion transport
J3K87_08800	COG0310	cobalt ion transport
J3K87_08805	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
J3K87_08810	COG0583	DNA-binding transcription factor activity
J3K87_08820	COG0490	domain, Protein
J3K87_08820	COG0471	metal ion transport
J3K87_08825	COG3722	fumarate hydratase activity
J3K87_08830	COG0246	Mannitol dehydrogenase
J3K87_08840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J3K87_08845	COG1349	DNA-binding transcription factor activity
J3K87_08860	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
J3K87_08875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J3K87_08880	COG2900	Belongs to the SlyX family
J3K87_08885	COG0545	Peptidyl-prolyl cis-trans isomerase
J3K87_08890	COG2964	Protein conserved in bacteria
J3K87_08895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J3K87_08905	COG2168	tRNA wobble position uridine thiolation
J3K87_08955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J3K87_08990	COG0561	phosphatase activity
J3K87_08995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3K87_09000	COG3012	SEC-C Motif Domain Protein
J3K87_09010	COG3716	PTS system mannose fructose sorbose family IID component
J3K87_09015	COG3715	PTS system
J3K87_09020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_09020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J3K87_09025	COG2610	gluconate transmembrane transporter activity
J3K87_09030	COG3265	gluconokinase activity
J3K87_09035	COG1609	Transcriptional regulator
J3K87_09045	COG1869	D-ribose catabolic process
J3K87_09055	COG1172	Belongs to the binding-protein-dependent transport system permease family
J3K87_09060	COG1879	ABC-type sugar transport system periplasmic component
J3K87_09065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J3K87_09070	COG0243	molybdopterin cofactor binding
J3K87_09075	COG0437	4 iron, 4 sulfur cluster binding
J3K87_09080	COG3302	dmso reductase anchor subunit
J3K87_09085	COG3381	protein complex oligomerization
J3K87_09090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J3K87_09090	COG2221	Nitrite and sulphite reductase 4Fe-4S
J3K87_09120	COG1349	DNA-binding transcription factor activity
J3K87_09125	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
J3K87_09130	COG1070	Carbohydrate kinase
J3K87_09135	COG4154	Belongs to the RbsD FucU family
J3K87_09140	COG0235	Class ii aldolase
J3K87_09145	COG0738	Major facilitator superfamily
J3K87_09150	COG1454	alcohol dehydrogenase
J3K87_09155	COG3477	response to acidic pH
J3K87_09160	COG0765	amino acid transport
J3K87_09170	COG1126	abc transporter atp-binding protein
J3K87_09175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3K87_09195	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J3K87_09220	COG3623	hexulose-6-phosphate isomerase
J3K87_09225	COG0235	Class ii aldolase
J3K87_09230	COG0545	Peptidyl-prolyl cis-trans isomerase
J3K87_09240	COG1476	TRANSCRIPTIONal
J3K87_09250	COG4783	chaperone-mediated protein folding
J3K87_09255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3K87_09265	COG0758	DNA mediated transformation
J3K87_09270	COG1297	OPT oligopeptide transporter protein
J3K87_09285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J3K87_09295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J3K87_09300	COG0081	regulation of translation
J3K87_09305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J3K87_09310	COG0222	ribosome binding
J3K87_09380	COG1487	ribonuclease activity
J3K87_09405	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J3K87_09415	COG0346	lactoylglutathione lyase activity
J3K87_09420	COG1194	a g-specific adenine glycosylase
J3K87_09425	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J3K87_09430	COG0741	lytic transglycosylase activity
J3K87_09445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J3K87_09450	COG0737	Belongs to the 5'-nucleotidase family
J3K87_09455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J3K87_09460	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J3K87_09465	COG0606	chelatase, subunit chli
J3K87_09480	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J3K87_09490	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
J3K87_09500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J3K87_09510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J3K87_09525	COG0051	transcription antitermination factor activity, RNA binding
J3K87_09530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J3K87_09535	COG0088	Forms part of the polypeptide exit tunnel
J3K87_09540	COG0089	rRNA binding
J3K87_09545	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J3K87_09550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J3K87_09555	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J3K87_09560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J3K87_09565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J3K87_09570	COG0255	Belongs to the universal ribosomal protein uL29 family
J3K87_09575	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J3K87_09585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J3K87_09590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J3K87_09595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J3K87_09600	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J3K87_09605	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J3K87_09610	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J3K87_09615	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J3K87_09620	COG1841	ribosomal large subunit assembly
J3K87_09625	COG0200	Binds to the 23S rRNA
J3K87_09630	COG0201	protein transport
J3K87_09640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J3K87_09645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J3K87_09650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J3K87_09655	COG0202	RNA polymerase activity
J3K87_09665	COG0228	four-way junction DNA binding
J3K87_09670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J3K87_09675	COG0336	Belongs to the RNA methyltransferase TrmD family
J3K87_09680	COG0335	large ribosomal subunit rRNA binding
J3K87_09685	COG2850	peptidyl-arginine hydroxylation
J3K87_09690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J3K87_09695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J3K87_09740	COG2852	Protein conserved in bacteria
J3K87_09765	COG2832	Protein of unknown function (DUF454)
J3K87_09775	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3K87_09785	COG0084	hydrolase, TatD family'
J3K87_09800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_09810	COG0470	DNA polymerase III
J3K87_09815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J3K87_09820	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J3K87_09840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3K87_09845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J3K87_09850	COG0254	rRNA binding
J3K87_09855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J3K87_09860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J3K87_09865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J3K87_09870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J3K87_09880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J3K87_09905	COG1595	DNA-templated transcription, initiation
J3K87_09920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J3K87_09945	COG2502	aspartate--ammonia ligase
J3K87_09950	COG1522	sequence-specific DNA binding
J3K87_09955	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J3K87_09960	COG3161	chorismate lyase activity
J3K87_10000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J3K87_10025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J3K87_10035	COG4208	sulfate ABC transporter
J3K87_10040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J3K87_10045	COG1304	FMN binding
J3K87_10055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J3K87_10065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J3K87_10070	COG2995	paraquat-inducible protein a
J3K87_10075	COG1305	Transglutaminase-like
J3K87_10085	COG2608	mercury ion transmembrane transporter activity
J3K87_10090	COG1979	alcohol dehydrogenase
J3K87_10095	COG0583	DNA-binding transcription factor activity
J3K87_10100	COG2171	N-acyltransferase activity
J3K87_10105	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J3K87_10115	COG0511	ligase activity, forming carbon-carbon bonds
J3K87_10120	COG0439	Biotin carboxylase
J3K87_10130	COG3084	Protein conserved in bacteria
J3K87_10135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J3K87_10145	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J3K87_10145	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J3K87_10155	COG1876	peptidase activity
J3K87_10165	COG1393	Belongs to the ArsC family
J3K87_10175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J3K87_10180	COG0564	pseudouridine synthase activity
J3K87_10190	COG0668	transmembrane transport
J3K87_10195	COG0439	Biotin carboxylase
J3K87_10205	COG1025	Belongs to the peptidase M16 family
J3K87_10210	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J3K87_10235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J3K87_10240	COG1067	ATP-dependent peptidase activity
J3K87_10245	COG3120	sequence-specific DNA binding
J3K87_10250	COG0180	Tryptophanyl-tRNA synthetase
J3K87_10270	COG0730	response to heat
J3K87_10285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J3K87_10290	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J3K87_10295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J3K87_10300	COG2116	formate transmembrane transporter activity
J3K87_10330	COG1070	Carbohydrate kinase
J3K87_10335	COG2115	Belongs to the xylose isomerase family
J3K87_10340	COG4213	ABC transporter substrate-binding protein
J3K87_10345	COG1129	ABC transporter
J3K87_10350	COG4214	carbohydrate transport
J3K87_10355	COG1609	Transcriptional regulator
J3K87_10355	COG2207	Transcriptional regulator
J3K87_10360	COG3590	peptidase
J3K87_10370	COG4145	pantothenate transmembrane transporter activity
J3K87_10375	COG3924	membrane
J3K87_10380	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J3K87_10385	COG2853	Lipoprotein
J3K87_10390	COG0676	glucose-6-phosphate 1-epimerase activity
J3K87_10405	COG0726	polysaccharide deacetylase
J3K87_10405	COG1649	PFAM Uncharacterised BCR, COG1649
J3K87_10410	COG1215	transferase activity, transferring glycosyl groups
J3K87_10420	COG0149	triose-phosphate isomerase activity
J3K87_10430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J3K87_10435	COG1238	metal cluster binding
J3K87_10450	COG4942	peptidase
J3K87_10450	COG1388	LysM domain
J3K87_10455	COG2818	Glycosylase
J3K87_10465	COG0700	Nucleoside recognition
J3K87_10470	COG3366	ferrous iron transmembrane transporter activity
J3K87_10480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J3K87_10485	COG0594	ribonuclease P activity
J3K87_10490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J3K87_10495	COG0174	glutamine synthetase
J3K87_10500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J3K87_10505	COG0494	nUDIX hydrolase
J3K87_10535	COG1490	D-aminoacyl-tRNA deacylase activity
J3K87_10540	COG1295	ribonuclease BN
J3K87_10590	COG1064	alcohol dehydrogenase
J3K87_10600	COG1923	regulation of RNA biosynthetic process
J3K87_10605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J3K87_10615	COG1694	Mazg nucleotide pyrophosphohydrolase
J3K87_10630	COG1309	transcriptional regulator
J3K87_10640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J3K87_10645	COG2003	Belongs to the UPF0758 family
J3K87_10650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J3K87_10655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J3K87_10670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J3K87_10675	COG0076	glutamate decarboxylase activity
J3K87_10680	COG0425	Belongs to the sulfur carrier protein TusA family
J3K87_10685	COG2391	methyltransferase activity
J3K87_10690	COG3085	chromosome segregation
J3K87_10710	COG0598	Magnesium transport protein CorA
J3K87_10715	COG2226	methyltransferase
J3K87_10730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J3K87_10735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J3K87_10740	COG0805	protein transport
J3K87_10760	COG1114	Component of the transport system for branched-chain amino acids
J3K87_10765	COG1028	Short-chain dehydrogenase reductase Sdr
J3K87_10770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J3K87_10775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J3K87_10780	COG0142	geranyltranstransferase activity
J3K87_10790	COG0431	NADPH-dependent FMN reductase
J3K87_10795	COG2259	Doxx family
J3K87_10800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J3K87_10805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J3K87_10810	COG0697	spore germination
J3K87_10815	COG4783	chaperone-mediated protein folding
J3K87_10825	COG1040	competence protein
J3K87_10840	COG0456	acetyltransferase
J3K87_10845	COG0513	Belongs to the DEAD box helicase family
J3K87_10855	COG0747	negative chemotaxis
J3K87_10865	COG1584	GPR1 FUN34 yaaH family protein
J3K87_10870	COG1120	ATPase activity
J3K87_10905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J3K87_10910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J3K87_10930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J3K87_10945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J3K87_10945	COG0140	phosphoribosyl-ATP diphosphatase activity
J3K87_10950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J3K87_10955	COG0024	Methionine aminopeptidase
J3K87_10970	COG1621	beta-fructofuranosidase activity
J3K87_10975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J3K87_10985	COG4591	ABC-type transport system involved in lipoprotein release permease component
J3K87_10990	COG1136	(ABC) transporter
J3K87_10995	COG4591	ABC-type transport system involved in lipoprotein release permease component
J3K87_11000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family