locus-tag	class	description
APPSER1_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
APPSER1_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APPSER1_00020	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APPSER1_00025	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APPSER1_00040	ENOG4105ERU	peptidase
APPSER1_00060	ENOG4105CJN	penicillin-binding protein
APPSER1_00065	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
APPSER1_00070	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
APPSER1_00080	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
APPSER1_00085	ENOG4105CNI	cell division protein FtsW
APPSER1_00095	ENOG4105DFU	Cell wall formation (By similarity)
APPSER1_00125	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
APPSER1_00130	ENOG4108JQ5	ABC transporter
APPSER1_00135	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APPSER1_00140	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
APPSER1_00165	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
APPSER1_00170	ENOG4105C3G	gtp-binding protein
APPSER1_00185	ENOG4108XTF	Outer Membrane Lipoprotein
APPSER1_00190	ENOG4105NBI	YecM protein
APPSER1_00195	ENOG4105C75	arginyL-tRNA synthetase
APPSER1_00205	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
APPSER1_00210	ENOG4105C2N	RNA methyltransferase TrmH family group 3
APPSER1_00215	ENOG4105JIM	Phosphatidylserine synthase
APPSER1_00220	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
APPSER1_00225	ENOG4105DTN	riboflavin biosynthesis protein ribF
APPSER1_00230	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
APPSER1_00235	ENOG4108VVQ	metallophosphoesterase
APPSER1_00240	ENOG41065U4	response regulator
APPSER1_00250	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
APPSER1_00255	ENOG4105DFA	alanine racemase domain protein
APPSER1_00265	ENOG4105CI3	gtp-binding protein typa
APPSER1_00270	ENOG41090BQ	Glutaredoxin
APPSER1_00280	ENOG4105DSJ	YicC domain protein
APPSER1_00285	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
APPSER1_00290	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
APPSER1_00295	ENOG4105WH1	Two component transcriptional regulator luxr family
APPSER1_00305	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
APPSER1_00340	ENOG4105DEF	Extracellular solute-binding protein, family 5
APPSER1_00345	ENOG4105DEF	Extracellular solute-binding protein, family 5
APPSER1_00350	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
APPSER1_00355	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APPSER1_00360	ENOG4105C3U	ABC transporter
APPSER1_00365	ENOG4108JQ7	(ABC) transporter
APPSER1_00380	ENOG4105M4H	endoribonuclease L-psp
APPSER1_00385	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APPSER1_00390	ENOG4105M2J	Glutaredoxin
APPSER1_00395	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
APPSER1_00400	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
APPSER1_00410	ENOG4105M15	transport protein ExbD
APPSER1_00415	ENOG4105M8K	biopolymer transport protein
APPSER1_00420	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
APPSER1_00425	ENOG4107QR8	Thioredoxin
APPSER1_00430	ENOG4105VDH	Dihydroxyacetone kinase
APPSER1_00435	ENOG4108UTZ	Dihydroxyacetone kinase
APPSER1_00440	ENOG4105CMT	Dihydroxyacetone kinase
APPSER1_00445	ENOG4105C3M	thioredoxin reductase
APPSER1_00450	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APPSER1_00455	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
APPSER1_00465	ENOG4108R99	pseudouridine synthase
APPSER1_00475	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
APPSER1_00480	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
APPSER1_00495	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
APPSER1_00510	ENOG4105C01	Dihydroxy-acid dehydratase
APPSER1_00515	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
APPSER1_00525	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
APPSER1_00530	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
APPSER1_00535	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
APPSER1_00540	ENOG4105DVI	reductase, NrfD
APPSER1_00555	ENOG4105C2W	permease
APPSER1_00565	ENOG4105CK7	Sodium proline symporter
APPSER1_00570	ENOG41069M3	Transcriptional regulator
APPSER1_00575	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
APPSER1_00590	ENOG4105E07	UPF0149 protein
APPSER1_00595	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
APPSER1_00600	ENOG4105R2J	Conserved Protein
APPSER1_00605	ENOG4105K70	DNA-binding protein
APPSER1_00610	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
APPSER1_00625	ENOG4105VEQ	Cold shock protein
APPSER1_00630	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
APPSER1_00635	ENOG4105CN1	protease
APPSER1_00640	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
APPSER1_00645	ENOG4105EAQ	(twin-arginine translocation) pathway signal
APPSER1_00650	ENOG4105C5X	domain protein
APPSER1_00665	ENOG4105K59	histidine triad (HIT) protein
APPSER1_00670	ENOG4105CC5	ABC transporter
APPSER1_00675	ENOG4105CC5	ABC transporter
APPSER1_00680	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APPSER1_00685	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APPSER1_00690	ENOG4105ETT	transcriptional Regulator, LysR family
APPSER1_00695	ENOG4105PAD	Hydrolase
APPSER1_00700	ENOG4107R11	Transcriptional regulator
APPSER1_00710	ENOG4105HDK	L-asparaginase
APPSER1_00735	ENOG4107VHA	regulatoR
APPSER1_00740	ENOG4107QQ0	gntp family
APPSER1_00745	ENOG4105BZW	Glycerate kinase
APPSER1_00750	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
APPSER1_00755	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
APPSER1_00760	ENOG4105EWT	decarboxylase family
APPSER1_00765	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APPSER1_00775	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APPSER1_00780	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
APPSER1_00785	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APPSER1_00790	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APPSER1_00795	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APPSER1_00800	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APPSER1_00805	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APPSER1_00810	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
APPSER1_00815	ENOG4105CJ2	(LipO)protein
APPSER1_00830	ENOG4105D8G	Major Facilitator superfamily
APPSER1_00835	ENOG4105II7	pyrroline-5-carboxylate reductase
APPSER1_00845	ENOG4107VXZ	Hydrolase
APPSER1_00860	ENOG4105DGN	Electron transport complex
APPSER1_00865	ENOG4108R3D	Electron transport complex
APPSER1_00870	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
APPSER1_00875	ENOG4105EN6	Membrane
APPSER1_00880	ENOG4105D6A	Electron transport complex
APPSER1_00895	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
APPSER1_00905	ENOG4105DP9	ABC transporter
APPSER1_00910	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
APPSER1_00915	ENOG4105DJ0	Poly(A) Polymerase
APPSER1_00920	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APPSER1_00930	ENOG4107H52	Dicarboxylate transport
APPSER1_00940	ENOG4108UYE	Lactoylglutathione lyase
APPSER1_00945	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
APPSER1_00950	ENOG4105K3M	)-transporter
APPSER1_00955	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
APPSER1_00960	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APPSER1_00965	ENOG4105DKP	glycosyl transferase, family 9
APPSER1_00970	ENOG4105CA9	Pyruvate kinase
APPSER1_00975	ENOG4108BY2	phosphohistidine phosphatase
APPSER1_00980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APPSER1_00985	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
APPSER1_00990	ENOG4105C8J	)-transporter
APPSER1_00995	ENOG4105DFE	Dna adenine methylase
APPSER1_01000	ENOG4105D49	3-dehydroquinate synthase
APPSER1_01005	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
APPSER1_01010	ENOG4108JQC	penicillin-binding protein 1A
APPSER1_01035	ENOG4105E4G	Type IV pilus
APPSER1_01040	ENOG4107YIM	Involved in the transcription termination process (By similarity)
APPSER1_01045	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
APPSER1_01050	ENOG4108ZAI	phosphatidylglycerophosphatase a
APPSER1_01055	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
APPSER1_01060	ENOG4105EIB	trna rrna methyltransferase
APPSER1_01065	ENOG4105ECY	inositol monophosphatase
APPSER1_01070	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APPSER1_01085	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
APPSER1_01135	ENOG4106B0W	Curli production assembly transport component CsgG
APPSER1_01145	ENOG4107Y60	(LipO)protein
APPSER1_01150	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
APPSER1_01155	ENOG41082NX	50s ribosomal protein l35
APPSER1_01160	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
APPSER1_01165	ENOG4108QD6	
APPSER1_01180	ENOG4105C37	(CBS) domain
APPSER1_01185	ENOG4108W1A	pseudouridine synthase
APPSER1_01190	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APPSER1_01195	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
APPSER1_01200	ENOG4108UJU	UPF0301 protein
APPSER1_01205	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
APPSER1_01215	ENOG4105M85	Bola protein
APPSER1_01240	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APPSER1_01250	ENOG4105M6F	mutator MutT protein
APPSER1_01255	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
APPSER1_01265	ENOG4105C8Y	Acetylornithine aminotransferase
APPSER1_01275	ENOG4108MVK	Receptor
APPSER1_01280	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
APPSER1_01285	ENOG4105C6T	cysteine synthase
APPSER1_01290	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
APPSER1_01295	ENOG4105CFH	Aspartokinase
APPSER1_01300	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APPSER1_01305	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
APPSER1_01310	ENOG4107QYX	exodeoxyribonuclease v alpha
APPSER1_01340	ENOG4105CIN	aminoacyl-histidine dipeptidase
APPSER1_01345	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
APPSER1_01350	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
APPSER1_01355	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APPSER1_01365	ENOG4108Z1B	Cyclase dehydrase
APPSER1_01370	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
APPSER1_01375	ENOG4105E0C	molybdate abc transporter
APPSER1_01380	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
APPSER1_01385	ENOG4105E3A	(ABC) transporter
APPSER1_01390	ENOG4105DA5	(ABC) transporter
APPSER1_01395	ENOG4107QMP	dna polymerase iii subunits gamma and tau
APPSER1_01400	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
APPSER1_01410	ENOG4105KME	endoribonuclease L-psp
APPSER1_01415	ENOG4105C6T	cysteine synthase
APPSER1_01420	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
APPSER1_01425	ENOG4105DIK	(ABC) transporter
APPSER1_01435	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
APPSER1_01440	ENOG4108MN8	Membrane
APPSER1_01445	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
APPSER1_01455	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
APPSER1_01460	ENOG4108RE7	deoxyribonuclease
APPSER1_01465	ENOG4105C4R	Atp-dependent dna helicase
APPSER1_01470	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APPSER1_01475	ENOG4105F38	ABC transporter, permease
APPSER1_01480	ENOG4105D38	putrescine abc transporter
APPSER1_01500	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APPSER1_01530	ENOG4105C5H	ABC transporter
APPSER1_01535	ENOG4105CUZ	uba thif-type nad fad binding protein
APPSER1_01545	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APPSER1_01550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APPSER1_01565	ENOG4107YD3	Thioesterase
APPSER1_01570	ENOG4105E02	MotA TolQ exbB proton channel
APPSER1_01585	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
APPSER1_01590	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APPSER1_01600	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
APPSER1_01605	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
APPSER1_01610	ENOG4106K28	UPF0283 membrane protein
APPSER1_01615	ENOG4105C5H	ABC transporter
APPSER1_01625	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APPSER1_01630	ENOG4105D06	uba thif-type nad fad binding protein
APPSER1_01640	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APPSER1_01645	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
APPSER1_01655	ENOG4105D3G	Pseudouridine synthase
APPSER1_01660	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
APPSER1_01665	ENOG4105D6S	protein involved in catabolism of external DNA
APPSER1_01670	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APPSER1_01680	ENOG4105C28	cystathionine
APPSER1_01685	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
APPSER1_01700	ENOG4105C9A	Phoh family
APPSER1_01735	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
APPSER1_01765	ENOG4105D0A	hydroxylase
APPSER1_01785	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
APPSER1_01795	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
APPSER1_01800	ENOG4108IUZ	ABC transporter
APPSER1_01805	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
APPSER1_01815	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
APPSER1_01820	ENOG4108WV1	Pfam:DUF477
APPSER1_01830	ENOG4108V0P	LemA family
APPSER1_01840	ENOG4105DM4	PTS System
APPSER1_01845	ENOG4105DE4	1-phosphofructokinase
APPSER1_01850	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
APPSER1_01860	ENOG4108ESZ	Glycogen debranching enzyme
APPSER1_01865	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
APPSER1_01870	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
APPSER1_01875	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
APPSER1_01890	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APPSER1_01905	ENOG4105I08	Pseudouridine synthase
APPSER1_01910	ENOG4105C2C	drug resistance transporter, Bcr CflA
APPSER1_01920	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
APPSER1_01930	ENOG4107TT5	NLP P60 protein
APPSER1_01940	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
APPSER1_01945	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
APPSER1_01950	ENOG4108MJ5	VirK protein
APPSER1_01960	ENOG4105CQ7	ATP-dependent helicase
APPSER1_01965	ENOG4108VMM	UPF0756 membrane protein
APPSER1_01975	ENOG4107RUE	extracellular solute-binding protein family 1
APPSER1_01980	ENOG4107QI1	Mate efflux family protein
APPSER1_01985	ENOG4107QKA	exodeoxyribonuclease V beta
APPSER1_01990	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
APPSER1_01995	ENOG4108JU5	Magnesium and cobalt efflux protein
APPSER1_02000	ENOG4108Q67	UPF0319 protein
APPSER1_02005	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APPSER1_02010	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
APPSER1_02015	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
APPSER1_02020	ENOG4105CXY	transporter
APPSER1_02025	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
APPSER1_02030	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
APPSER1_02035	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
APPSER1_02040	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
APPSER1_02045	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APPSER1_02050	ENOG4108R6K	riboflavin synthase, subunit alpha
APPSER1_02065	ENOG4108RRZ	Transcription elongation factor GreB
APPSER1_02070	ENOG4105C2X	Arabinose 5-phosphate isomerase
APPSER1_02080	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
APPSER1_02085	ENOG4105C09	Bile acid
APPSER1_02090	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APPSER1_02095	ENOG4105DQF	Hydrolase
APPSER1_02100	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APPSER1_02105	ENOG4105EMN	RNA polymerase sigma factor
APPSER1_02110	ENOG41069PW	sigma-e factor negative regulatory protein
APPSER1_02120	ENOG4105CEY	Amp-dependent synthetase and ligase
APPSER1_02125	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
APPSER1_02130	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
APPSER1_02135	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
APPSER1_02140	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
APPSER1_02145	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
APPSER1_02160	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
APPSER1_02170	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APPSER1_02185	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APPSER1_02190	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APPSER1_02200	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APPSER1_02205	ENOG4105DZP	Membrane-associated zinc metalloprotease
APPSER1_02210	ENOG4105KNE	Phosphatidate cytidylyltransferase
APPSER1_02215	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
APPSER1_02220	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
APPSER1_02230	ENOG4105EYK	Phosphatidylglycerophosphatase B
APPSER1_02235	ENOG4105HBR	Rna-binding protein
APPSER1_02240	ENOG4106WTF	Glycosyl transferase, family 2
APPSER1_02245	ENOG41061WM	D-Alanyl-D-Alanine
APPSER1_02250	ENOG4105M5K	heptosyltransferase
APPSER1_02260	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APPSER1_02265	ENOG4105E96	Colicin v production protein
APPSER1_02270	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
APPSER1_02280	ENOG4105D82	Glutamate dehydrogenase
APPSER1_02285	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APPSER1_02295	ENOG4105KME	endoribonuclease L-psp
APPSER1_02300	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
APPSER1_02320	ENOG4105E0X	reductase
APPSER1_02325	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
APPSER1_02330	ENOG4105DFF	Rod shape-determining protein mreb
APPSER1_02335	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
APPSER1_02345	ENOG4105D1H	recombination factor protein RarA
APPSER1_02350	ENOG4105FAV	ABC, transporter
APPSER1_02355	ENOG4105E7A	Glutamine amidotransferase
APPSER1_02360	ENOG4105DWV	Homoserine O-trans-acetylase
APPSER1_02365	ENOG4107GZ4	SanA protein
APPSER1_02380	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
APPSER1_02385	ENOG4107QR9	Iron-sulfur cluster binding protein
APPSER1_02390	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
APPSER1_02395	ENOG4105DAA	L-lactate
APPSER1_02400	ENOG4108SAU	DNA-binding protein H-ns
APPSER1_02405	ENOG4107S6Z	Na H antiporter
APPSER1_02410	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
APPSER1_02415	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
APPSER1_02425	ENOG4108MJ5	VirK protein
APPSER1_02430	ENOG4105C7S	Dehydrogenase
APPSER1_02435	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
APPSER1_02440	ENOG4105FDK	ABC transporter
APPSER1_02445	ENOG4105DR5	peptidase
APPSER1_02450	ENOG4105T95	Thiol disulfide interChange protein
APPSER1_02455	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
APPSER1_02465	ENOG4108K4B	hydrolase
APPSER1_02470	ENOG4105BZU	Histidine kinase
APPSER1_02480	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APPSER1_02490	ENOG4105CKU	formyltetrahydrofolate synthetase
APPSER1_02495	ENOG4108ZZ3	UPF0260 protein
APPSER1_02500	ENOG4105EMU	Dehydrogenase
APPSER1_02505	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APPSER1_02515	ENOG4105X5T	
APPSER1_02525	ENOG4105C2M	dna polymerase I
APPSER1_02530	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
APPSER1_02535	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
APPSER1_02540	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
APPSER1_02570	ENOG41080HT	Transcriptional regulator, arsr family
APPSER1_02585	ENOG41080C8	DUF218 domain
APPSER1_02590	ENOG4105C6K	Malic enzyme
APPSER1_02595	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
APPSER1_02695	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APPSER1_02700	ENOG4105RDA	repressor
APPSER1_02730	ENOG4108MXB	Protein of unknown function (DUF968)
APPSER1_02810	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APPSER1_02890	ENOG41065CD	Exported protein
APPSER1_02895	ENOG4105D7X	high-affinity nickel-transporter
APPSER1_02900	ENOG4105BZG	amino acid carrier protein
APPSER1_02905	ENOG4108YI8	ABC transporter
APPSER1_02910	ENOG4108YI8	ABC transporter
APPSER1_02920	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
APPSER1_02925	ENOG4105D06	uba thif-type nad fad binding protein
APPSER1_02930	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
APPSER1_02935	ENOG4105D41	biosynthesis protein thiH
APPSER1_02940	ENOG4105ETU	transcriptional activator (TenA
APPSER1_02945	ENOG4107Z6I	Thiamine biosynthesis protein
APPSER1_02960	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
APPSER1_02965	ENOG4105C3F	Signal peptidase i
APPSER1_02970	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
APPSER1_02975	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
APPSER1_02980	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
APPSER1_03055	ENOG4105C1J	atp-dependent rna helicase
APPSER1_03065	ENOG4105D7A	ATP-binding protein
APPSER1_03070	ENOG4105C4Y	ABC transporter
APPSER1_03075	ENOG4107RCV	ABC transporter, permease
APPSER1_03100	ENOG4108I6E	Sulfatase
APPSER1_03105	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
APPSER1_03110	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
APPSER1_03115	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APPSER1_03130	ENOG4108Z6B	deaminase
APPSER1_03135	ENOG4105C1J	atp-dependent rna helicase
APPSER1_03140	ENOG4105RT1	May be involved in cell division (By similarity)
APPSER1_03145	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
APPSER1_03150	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APPSER1_03165	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
APPSER1_03180	ENOG4105E68	Sulfatase
APPSER1_03185	ENOG4105YDX	UPF0352 protein
APPSER1_03190	ENOG4105Y7M	Transcriptional regulator, TetR family
APPSER1_03195	ENOG410624X	efflux transporter, rnd family, mfp subunit
APPSER1_03200	ENOG4105BZS	acriflavin resistance protein
APPSER1_03215	ENOG4105TWJ	Domain of unknown function (DUF1919)
APPSER1_03220	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
APPSER1_03235	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APPSER1_03240	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
APPSER1_03245	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
APPSER1_03250	ENOG4105E0U	tyrosine-specific transport protein
APPSER1_03255	ENOG4105E0U	tyrosine-specific transport protein
APPSER1_03265	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
APPSER1_03270	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
APPSER1_03280	ENOG4105D1Q	UPF0246 protein
APPSER1_03290	ENOG41076HS	cation diffusion facilitator family transporter
APPSER1_03295	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
APPSER1_03300	ENOG4107R6U	sodium dicarboxylate symporter
APPSER1_03305	ENOG4108RCM	Nitroreductase
APPSER1_03310	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
APPSER1_03315	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
APPSER1_03320	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APPSER1_03325	ENOG4108QBX	(LipO)protein
APPSER1_03335	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
APPSER1_03340	ENOG4105E2R	ROK family
APPSER1_03345	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
APPSER1_03350	ENOG4105EW9	transcriptional regulator AsnC family
APPSER1_03355	ENOG4105CNU	cell division protein FtsK
APPSER1_03360	ENOG4105CGZ	zinc metallopeptidase
APPSER1_03365	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APPSER1_03370	ENOG41072GX	Peptidase M22 Glycoprotease
APPSER1_03375	ENOG4107104	thymidine kinase
APPSER1_03380	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
APPSER1_03385	ENOG4105CBT	Fructose-1,6-bisphosphatase
APPSER1_03390	ENOG4107QNR	UPF0135 protein
APPSER1_03395	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APPSER1_03400	ENOG4105E0F	Histidine kinase
APPSER1_03405	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APPSER1_03410	ENOG4105DXN	mazG family
APPSER1_03420	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
APPSER1_03430	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
APPSER1_03435	ENOG4105CHV	Transcription elongation factor NusA
APPSER1_03440	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
APPSER1_03445	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
APPSER1_03450	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
APPSER1_03455	ENOG4105CVE	Lytic murein transglycosylase
APPSER1_03460	ENOG4107EPN	Domain of unknown function (DUF1508)
APPSER1_03465	ENOG4108DNC	Involved in acetate metabolism (By similarity)
APPSER1_03475	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
APPSER1_03495	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
APPSER1_03505	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
APPSER1_03520	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
APPSER1_03525	ENOG4105KB2	stringent starvation protein b
APPSER1_03530	ENOG4107MKT	Stringent starvation protein a
APPSER1_03535	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
APPSER1_03540	ENOG4105HDK	L-asparaginase
APPSER1_03545	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
APPSER1_03550	ENOG4105CGF	Aromatic amino acid aminotransferase
APPSER1_03555	ENOG4107RAQ	aminopeptidase
APPSER1_03565	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APPSER1_03570	ENOG410650H	(LipO)protein
APPSER1_03575	ENOG4105DBE	peroxidase
APPSER1_03585	ENOG4105DB7	PHP domain protein
APPSER1_03595	ENOG4105CJB	Exodeoxyribonuclease I
APPSER1_03605	ENOG4105C5S	asparaginyl-tRNA synthetase
APPSER1_03610	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
APPSER1_03620	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APPSER1_03625	ENOG4105CX6	glutaminyL-tRNA synthetase
APPSER1_03635	ENOG4107SC1	transglycosylase
APPSER1_03640	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
APPSER1_03645	ENOG4105C28	cystathionine
APPSER1_03650	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
APPSER1_03655	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
APPSER1_03660	ENOG4105M08	Membrane
APPSER1_03665	ENOG4105CXG	d-lactate dehydrogenase
APPSER1_03670	ENOG4107QY8	reductase
APPSER1_03675	ENOG4105CUW	cytochrome C-TYPE protein
APPSER1_03685	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APPSER1_03690	ENOG4105M00	molybdopterin converting factor, subunit 1
APPSER1_03695	ENOG4108ZAF	Molybdopterin
APPSER1_03700	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
APPSER1_03705	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
APPSER1_03710	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APPSER1_03715	ENOG4105CC0	LysR family Transcriptional regulator
APPSER1_03725	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
APPSER1_03740	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
APPSER1_03745	ENOG4105C0D	helicase
APPSER1_03765	ENOG4105QEK	Transcriptional regulator
APPSER1_03770	ENOG4108R66	Conserved Protein
APPSER1_03775	ENOG4105C9X	ppx gppa phosphatase
APPSER1_03785	ENOG4105CFH	Aspartokinase
APPSER1_03790	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
APPSER1_03795	ENOG4105VNG	YcgL domain-containing protein
APPSER1_03800	ENOG4105CDU	Replicative dna helicase
APPSER1_03810	ENOG4105DHS	permease protein
APPSER1_03815	ENOG4105CM4	permease protein
APPSER1_03820	ENOG4108IPW	abc transporter atp-binding protein
APPSER1_03825	ENOG4107IX6	phosphate transport regulator
APPSER1_03830	ENOG4105CJ3	phosphate transporter
APPSER1_03845	ENOG4105NSG	hemerythrin hhe cation binding domain protein
APPSER1_03850	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
APPSER1_03860	ENOG4105VEQ	Cold shock protein
APPSER1_03865	ENOG41077A9	carbonic anhydrase
APPSER1_03870	ENOG4105C7K	acetolactate synthase
APPSER1_03875	ENOG4108ZP8	Acetolactate synthase small subunit
APPSER1_03880	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
APPSER1_03885	ENOG4105N42	UPF0307 protein
APPSER1_03895	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
APPSER1_03900	ENOG4108UQV	Membrane
APPSER1_03905	ENOG4108ZPB	UPF0306 protein
APPSER1_03910	ENOG4108ZJT	translation initiation factor, Sui1
APPSER1_03915	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
APPSER1_03920	ENOG4105CFV	Tetratricopeptide repeat protein
APPSER1_03925	ENOG4105Q4A	inner membrane protein yciS
APPSER1_03930	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APPSER1_03935	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
APPSER1_03940	ENOG4105CAT	Cytidine monophosphate kinase
APPSER1_03945	ENOG4105C0H	protease
APPSER1_03960	ENOG4108IYH	Dna topoisomerase
APPSER1_03965	ENOG4105G6Z	alkaline phosphatase
APPSER1_03970	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
APPSER1_03980	ENOG4105EGS	Mechanosensitive ion channel
APPSER1_03985	ENOG4105EGS	Mechanosensitive ion channel
APPSER1_03990	ENOG4105CEY	Amp-dependent synthetase and ligase
APPSER1_03995	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
APPSER1_04000	ENOG4105EV9	Alpha Beta Hydrolase
APPSER1_04005	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
APPSER1_04010	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
APPSER1_04025	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
APPSER1_04030	ENOG4105VAW	lrga family
APPSER1_04035	ENOG41067MG	lrgb family
APPSER1_04040	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
APPSER1_04055	ENOG4105DVA	methyltransferase
APPSER1_04065	ENOG4105CHW	UPF0052 protein
APPSER1_04075	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
APPSER1_04080	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
APPSER1_04090	ENOG41080IJ	Diacylglycerol kinase
APPSER1_04095	ENOG4105CGH	5'-nucleotidase
APPSER1_04120	ENOG4107QN2	dihydrolipoyl dehydrogenase
APPSER1_04125	ENOG4107QSN	dihydrolipoamide acetyltransferase
APPSER1_04130	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
APPSER1_04135	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
APPSER1_04140	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
APPSER1_04155	ENOG4105BZ1	(ABC) transporter
APPSER1_04160	ENOG41067MG	lrgb family
APPSER1_04170	ENOG4105DVT	helicase
APPSER1_04180	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APPSER1_04185	ENOG4108UUM	single-stranded DNA-binding protein
APPSER1_04215	ENOG4105EA8	2-Nitropropane dioxygenase
APPSER1_04225	ENOG4105UNS	Pfam:DUF419
APPSER1_04230	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
APPSER1_04235	ENOG4108EU3	peptide transport system, permease
APPSER1_04245	ENOG4108EVY	peptide transport periplasmic protein
APPSER1_04250	ENOG4108JU8	Transcriptional regulator
APPSER1_04255	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
APPSER1_04260	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
APPSER1_04265	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
APPSER1_04285	ENOG4105E0M	Sulfatase
APPSER1_04290	ENOG4105QVC	MOSC domain-containing protein
APPSER1_04300	ENOG4105CTB	Polyprenyl synthetase
APPSER1_04310	ENOG4105CRK	lysyL-tRNA synthetase
APPSER1_04315	ENOG4105C03	ribonuclease
APPSER1_04320	ENOG4105DDY	UPF0142 protein ycaO
APPSER1_04330	ENOG4107QMH	DNA methylase
APPSER1_04335	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
APPSER1_04345	ENOG4105CA3	membrane-bound lytic murein transglycosylase
APPSER1_04365	ENOG4105VT2	5-hydroxyisourate hydrolase
APPSER1_04375	ENOG4108VD1	dedA family
APPSER1_04380	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APPSER1_04390	ENOG4105E98	transcriptional regulator DeoR family
APPSER1_04395	ENOG4107QTF	adenylosuccinate lyase
APPSER1_04400	ENOG41075W9	High frequency lysogenization protein HflD homolog
APPSER1_04405	ENOG4108JJ8	(ABC) transporter
APPSER1_04410	ENOG4108JJ9	ABC, transporter
APPSER1_04415	ENOG4105MA0	exported protein
APPSER1_04420	ENOG4105CFU	surface antigen
APPSER1_04425	ENOG4105PXI	polysaccharide deacetylase
APPSER1_04430	ENOG41063SB	peptidase
APPSER1_04435	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APPSER1_04445	ENOG4105DBI	uridine monophosphokinase
APPSER1_04450	ENOG4105DHP	deoxycytidine triphosphate deaminase
APPSER1_04460	ENOG4105D0S	secretion protein (HlyD
APPSER1_04465	ENOG4105CJ1	ABC, transporter
APPSER1_04470	ENOG4105CMI	transporter
APPSER1_04480	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APPSER1_04485	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APPSER1_04490	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
APPSER1_04500	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
APPSER1_04505	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APPSER1_04510	ENOG4105CSA	Coproporphyrinogen iii oxidase
APPSER1_04515	ENOG4107QSI	ABC, transporter
APPSER1_04530	ENOG4108JQ7	(ABC) transporter
APPSER1_04545	ENOG4105SYT	Methylenetetrahydrofolate reductase
APPSER1_04550	ENOG4105DEF	Extracellular solute-binding protein, family 5
APPSER1_04555	ENOG4105C44	Serine transporter
APPSER1_04560	ENOG4105EJQ	L-serine dehydratase
APPSER1_04570	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APPSER1_04580	ENOG4105WP7	tRNA pseudouridine synthase C
APPSER1_04585	ENOG4105DR9	pseudouridine synthase
APPSER1_04600	ENOG4105I7R	Adenylate cyclase
APPSER1_04605	ENOG4105CM6	amino acid regulated cytosolic protein
APPSER1_04610	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
APPSER1_04620	ENOG4105CH2	amidohydrolase
APPSER1_04635	ENOG4105C8T	Leucyl-tRNA synthetase
APPSER1_04645	ENOG4105DJF	DNA polymerase III, delta' subunit
APPSER1_04650	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
APPSER1_04655	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
APPSER1_04665	ENOG4105D7Q	type ii secretion system
APPSER1_04670	ENOG4107QHF	type ii secretion system protein e
APPSER1_04680	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
APPSER1_04690	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
APPSER1_04695	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
APPSER1_04700	ENOG4105EJ9	Membrane
APPSER1_04705	ENOG4105CSM	endonuclease III
APPSER1_04730	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
APPSER1_04735	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APPSER1_04740	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APPSER1_04745	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
APPSER1_04750	ENOG4108MG3	formate dehydrogenase
APPSER1_04755	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
APPSER1_04785	ENOG4105D1S	lipid A biosynthesis
APPSER1_04790	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
APPSER1_04800	ENOG4105EUJ	GTP cyclohydrolase i
APPSER1_04805	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
APPSER1_04815	ENOG4108UW5	maltose o-acetyltransferase
APPSER1_04830	ENOG4105ZIA	Phage protein gp16
APPSER1_04840	ENOG41065S5	
APPSER1_04850	ENOG4105IKI	host-nuclease inhibitor protein
APPSER1_04945	ENOG4105CF2	Mu-like prophage FluMu protein GP28
APPSER1_05050	ENOG4107H6E	
APPSER1_05055	ENOG4105ENX	hydrolase
APPSER1_05060	ENOG4105EQ2	LysR family Transcriptional regulator
APPSER1_05065	ENOG4105D01	(LipO)protein
APPSER1_05070	ENOG4105D01	(LipO)protein
APPSER1_05075	ENOG4108UMI	ABC transporter, permease
APPSER1_05080	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
APPSER1_05095	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APPSER1_05100	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APPSER1_05110	ENOG4105UGU	tonB-dependent Receptor
APPSER1_05135	ENOG4105WVQ	Fe-S assembly protein IscX
APPSER1_05140	ENOG4108ZIT	Ferredoxin, 2FE-2S
APPSER1_05150	ENOG4108RF1	Protein of unknown function DUF2625
APPSER1_05160	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
APPSER1_05165	ENOG4108Z4V	iron-sulfur cluster assembly
APPSER1_05170	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
APPSER1_05175	ENOG4105C3J	Cysteine desulfurase
APPSER1_05180	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
APPSER1_05185	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
APPSER1_05190	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
APPSER1_05195	ENOG4105BZU	Histidine kinase
APPSER1_05200	ENOG4108TZV	Membrane
APPSER1_05205	ENOG4108DG9	Smr protein MutS2
APPSER1_05210	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
APPSER1_05215	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
APPSER1_05220	ENOG4105HSA	Protein of unknown function (DUF452)
APPSER1_05225	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APPSER1_05230	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APPSER1_05235	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
APPSER1_05240	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APPSER1_05245	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
APPSER1_05280	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
APPSER1_05285	ENOG4105DC1	bifunctional purine biosynthesis protein purh
APPSER1_05295	ENOG4105CKT	filamentous hemagglutinin
APPSER1_05315	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
APPSER1_05320	ENOG4105D4P	Coproporphyrinogen iii oxidase
APPSER1_05335	ENOG4105D0C	transport protein
APPSER1_05340	ENOG4105D6U	Sodium Glutamate Symporter
APPSER1_05350	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
APPSER1_05355	ENOG4105K9H	YciI-like protein
APPSER1_05360	ENOG4105NAU	thioesterase Superfamily protein
APPSER1_05375	ENOG4105PQ6	UPF0208 membrane protein
APPSER1_05385	ENOG4105D3Y	Na H antiporter
APPSER1_05390	ENOG4105CGK	Exodeoxyribonuclease III
APPSER1_05395	ENOG4105EMY	transcriptional regulator
APPSER1_05405	ENOG4105W1T	Glycosyl Transferase
APPSER1_05420	ENOG4105VFB	Binds the 23S rRNA (By similarity)
APPSER1_05425	ENOG4105CV1	Transketolase (EC 2.2.1.1)
APPSER1_05435	ENOG4105CH6	catalase
APPSER1_05445	ENOG4107RN3	metallophosphoesterase
APPSER1_05450	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APPSER1_05455	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APPSER1_05460	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
APPSER1_05470	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
APPSER1_05475	ENOG4105CNT	hydrolase family 2
APPSER1_05490	ENOG4105D1F	ATP-binding protein
APPSER1_05500	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
APPSER1_05505	ENOG4105EIN	peptidylprolyl cis-trans isomerase
APPSER1_05510	ENOG4105EEQ	Na H antiporter
APPSER1_05515	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
APPSER1_05520	ENOG4105CKW	Inner membrane protein yedI
APPSER1_05525	ENOG410601J	HemY protein
APPSER1_05530	ENOG4105ECF	c-methyltransferase
APPSER1_05535	ENOG41076E6	Uroporphyrinogen-III Synthase
APPSER1_05540	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
APPSER1_05545	ENOG4108EKI	Dehydrogenase
APPSER1_05560	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
APPSER1_05565	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
APPSER1_05570	ENOG4105D9N	nucleoside
APPSER1_05575	ENOG4108VW9	Membrane
APPSER1_05580	ENOG4108UHU	Aldolase
APPSER1_05585	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
APPSER1_05590	ENOG4105D2H	Uronic isomerase
APPSER1_05600	ENOG4107YCY	Transcriptional regulator
APPSER1_05610	ENOG4105E0X	reductase
APPSER1_05615	ENOG4108RYC	glycosyltransferase
APPSER1_05620	ENOG4108RJ9	Glycosyl transferase, family 2
APPSER1_05630	ENOG41068D6	Glycosyltransferase
APPSER1_05640	ENOG4108ZPC	Polysaccharide pyruvyl transferase
APPSER1_05645	ENOG41080C8	DUF218 domain
APPSER1_05650	ENOG4105C25	Primosomal protein n'
APPSER1_05655	ENOG4105CQC	Prephenate dehydratase
APPSER1_05660	ENOG4105DGW	oligopeptidase A
APPSER1_05665	ENOG4105F1A	Pyruvate formate-lyase
APPSER1_05670	ENOG4105C6N	Formate acetyltransferase
APPSER1_05675	ENOG4105TMB	Formate nitrite transporter
APPSER1_05680	ENOG4105W39	Membrane
APPSER1_05685	ENOG4105D0M	Protease HtpX homolog
APPSER1_05695	ENOG4105DWU	Membrane
APPSER1_05700	ENOG4105E4F	Isochorismate synthase
APPSER1_05705	ENOG4105CHM	Aminotransferase
APPSER1_05710	ENOG4105DTR	rard protein
APPSER1_05715	ENOG4105DTR	rard protein
APPSER1_05730	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
APPSER1_05740	ENOG4108DMF	Cytochrome C biogenesis protein
APPSER1_05745	ENOG4107QX9	Thiol disulfide interChange protein
APPSER1_05750	ENOG4105DA4	cytochrome c-type biogenesis protein
APPSER1_05755	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
APPSER1_05760	ENOG4107T0K	Adenylate cyclase
APPSER1_05765	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APPSER1_05780	ENOG4105WXI	Bacterial OB fold (BOF) protein
APPSER1_05795	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
APPSER1_05800	ENOG4105DHQ	Histidine kinase
APPSER1_05805	ENOG4108UUE	Transcriptional regulator
APPSER1_05810	ENOG4105VIE	preprotein translocase, subunit YajC
APPSER1_05815	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APPSER1_05820	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APPSER1_05825	ENOG41090A1	ferritin
APPSER1_05830	ENOG41090A1	ferritin
APPSER1_05835	ENOG4105C7N	Xanthine uracil vitamin C permease
APPSER1_05840	ENOG4108Z03	MAF-like protein
APPSER1_05855	ENOG4105HEI	LysR family (Transcriptional regulator
APPSER1_05870	ENOG4105E4P	ATPase (AAA
APPSER1_05885	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APPSER1_05890	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
APPSER1_05895	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APPSER1_05905	ENOG4105EPW	hflc protein
APPSER1_05910	ENOG4107QJR	hflk protein
APPSER1_05915	ENOG4105K63	Thioredoxin
APPSER1_05935	ENOG4105D5Q	Arginine ornithine antiporter
APPSER1_05940	ENOG4105D5Q	Arginine ornithine antiporter
APPSER1_05950	ENOG4105CWC	Acetylornithine deacetylase
APPSER1_05955	ENOG4105EIF	outer membrane protein W
APPSER1_05960	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APPSER1_05965	ENOG4105D6J	arsenicaL-resistance protein
APPSER1_05970	ENOG4105K89	arsenate reductase
APPSER1_05980	ENOG4108IJ0	Aspartate ammonia-lyase
APPSER1_05990	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
APPSER1_05995	ENOG41069UX	Beta-N-acetyl-hexosaminidase
APPSER1_06005	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
APPSER1_06010	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
APPSER1_06035	ENOG4108M8S	permease YjgP YjgQ family protein
APPSER1_06040	ENOG4108K5H	permease YjgP YjgQ family protein
APPSER1_06045	ENOG4105C0B	DNA polymerase III (alpha subunit)
APPSER1_06050	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
APPSER1_06055	ENOG4105E55	glycerol-3-phosphate acyltransferase
APPSER1_06060	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APPSER1_06065	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
APPSER1_06070	ENOG4105EE5	Membrane protein terC
APPSER1_06075	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
APPSER1_06080	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
APPSER1_06085	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APPSER1_06095	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
APPSER1_06100	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APPSER1_06105	ENOG4105XQ6	frataxin-like protein
APPSER1_06110	ENOG4107J0A	lipopolysaccharide biosynthetic process
APPSER1_06115	ENOG4107J0A	lipopolysaccharide biosynthetic process
APPSER1_06120	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APPSER1_06125	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APPSER1_06130	ENOG4105C34	Pseudouridine synthase
APPSER1_06135	ENOG4108VTV	Inherit from NOG: Membrane
APPSER1_06140	ENOG4105CTQ	phosphohexokinase
APPSER1_06145	ENOG4105C9B	Cysteine desulfurase
APPSER1_06150	ENOG4105KK6	nuclease
APPSER1_06155	ENOG4105BZG	amino acid carrier protein
APPSER1_06160	ENOG4105DSF	transport protein
APPSER1_06170	ENOG4105CFP	Peptidase U32
APPSER1_06175	ENOG4105PF3	O-Antigen polymerase
APPSER1_06180	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
APPSER1_06190	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
APPSER1_06195	ENOG4105K8N	protein family UPF0079, ATPase
APPSER1_06200	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
APPSER1_06205	ENOG4107QP8	phosphohexose isomerase
APPSER1_06210	ENOG4105W0Z	cytoplasmic protein
APPSER1_06230	ENOG4105E2X	shikimate dehydrogenase
APPSER1_06240	ENOG4108WI1	Dna topoisomerase
APPSER1_06245	ENOG41060QA	UPF0267 protein
APPSER1_06250	ENOG4105Y3E	Modulates RecA activity (By similarity)
APPSER1_06255	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
APPSER1_06265	ENOG4105CRQ	synthase (Component I)
APPSER1_06270	ENOG4105CGY	Dna recombination protein
APPSER1_06275	ENOG4105DDQ	anthranilate synthase
APPSER1_06285	ENOG4105C9M	aspartyl-trna synthetase
APPSER1_06290	ENOG4108TIT	dATP pyrophosphohydrolase
APPSER1_06305	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
APPSER1_06310	ENOG4107RAN	Peptidase, M16
APPSER1_06320	ENOG4107QPK	)-transporter
APPSER1_06325	ENOG4105DZ2	Transcriptional regulator
APPSER1_06330	ENOG4106ZV1	Transferrin binding protein-like solute binding protein
APPSER1_06335	ENOG4105FE9	pseudouridine synthase
APPSER1_06340	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
APPSER1_06350	ENOG4105EZR	dyp-type peroxidase family protein
APPSER1_06355	ENOG4105CRQ	synthase (Component I)
APPSER1_06360	ENOG4105DDQ	anthranilate synthase
APPSER1_06370	ENOG4105DMQ	Methyltransferase
APPSER1_06375	ENOG4105RHG	
APPSER1_06380	ENOG4105Z2P	Protein of unknown function (DUF465)
APPSER1_06395	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
APPSER1_06405	ENOG4105C12	Phosphoribosylglycinamide synthetase
APPSER1_06415	ENOG4105N21	Membrane
APPSER1_06425	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
APPSER1_06430	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
APPSER1_06435	ENOG4105CHH	sulfate transporter
APPSER1_06445	ENOG4105D9R	oxidoreductase
APPSER1_06450	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
APPSER1_06465	ENOG4105EXG	Transcriptional regulator
APPSER1_06495	ENOG4108ZHJ	Organic hydroperoxide resistance protein
APPSER1_06525	ENOG4105CF7	AraC family transcriptional regulator
APPSER1_06535	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APPSER1_06540	ENOG4105DEN	Luciferase family
APPSER1_06545	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
APPSER1_06550	ENOG4108RCM	Nitroreductase
APPSER1_06555	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
APPSER1_06565	ENOG4105C4W	S-formylglutathione hydrolase
APPSER1_06590	ENOG4105C94	Transporter
APPSER1_06605	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
APPSER1_06610	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
APPSER1_06625	ENOG4105BZ1	(ABC) transporter
APPSER1_06630	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
APPSER1_06635	ENOG4105DY2	Paraquat-inducible protein b
APPSER1_06640	ENOG41090R7	Ferric uptake
APPSER1_06645	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
APPSER1_06650	ENOG4105NNH	LexA regulated protein
APPSER1_06655	ENOG4108Z66	YbaK ebsC protein
APPSER1_06660	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APPSER1_06665	ENOG4105C7N	Xanthine uracil vitamin C permease
APPSER1_06670	ENOG41090EX	DsrE family
APPSER1_06675	ENOG4105CBX	hi0933 family
APPSER1_06680	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
APPSER1_06685	ENOG41062Z9	Membrane
APPSER1_06690	ENOG4105EAC	phosphoserine phosphatase
APPSER1_06705	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
APPSER1_06710	ENOG41061ZR	Transcriptional regulator
APPSER1_06715	ENOG4107W52	maltose operon periplasmic protein
APPSER1_06720	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
APPSER1_06725	ENOG4108IJ9	(ABC) transporter
APPSER1_06730	ENOG4107FKK	extracellular solute-binding protein family 1
APPSER1_06735	ENOG4105D56	permease protein
APPSER1_06740	ENOG4105EG2	ABC transporter, permease
APPSER1_06745	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
APPSER1_06755	ENOG4105EYA	deoxyribonuclease
APPSER1_06760	ENOG4105DC8	reductase
APPSER1_06765	ENOG4108TEB	UPF0114 protein
APPSER1_06770	ENOG4108TVJ	Nitroreductase
APPSER1_06790	ENOG4105D2N	Aldolase
APPSER1_06795	ENOG4105BZA	Phosphoglycerate kinase
APPSER1_06800	ENOG4105C8P	)-transporter
APPSER1_06805	ENOG4105C8P	)-transporter
APPSER1_06810	ENOG4105C8P	)-transporter
APPSER1_06815	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APPSER1_06820	ENOG4105BZU	Histidine kinase
APPSER1_06825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APPSER1_06830	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APPSER1_06840	ENOG4105C8U	phosphate abc transporter
APPSER1_06845	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
APPSER1_06850	ENOG4108Z6Z	Transcriptional regulator
APPSER1_06865	ENOG4105C59	p-type ATPase
APPSER1_06870	ENOG4105E1F	short-chain dehydrogenase reductase
APPSER1_06875	ENOG41069NU	Nitroreductase
APPSER1_06880	ENOG4105D07	Signal peptide peptidase, SppA
APPSER1_06885	ENOG41083KI	ribonuclease, T2
APPSER1_06890	ENOG4105GPY	SprT protein
APPSER1_06895	ENOG4105CEP	NADH dehydrogenase
APPSER1_06900	ENOG4105BZM	domain protein
APPSER1_06905	ENOG41090FY	type IV pilus biogenesis stability protein PilW
APPSER1_06910	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APPSER1_06945	ENOG4105VTW	prevent-host-death family
APPSER1_06950	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
APPSER1_06955	ENOG4105W49	UPF0434 protein
APPSER1_06965	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
APPSER1_06970	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APPSER1_06975	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
APPSER1_06990	ENOG4108JDX	DNA polymerase iii, epsilon subunit
APPSER1_06995	ENOG4105C5H	ABC transporter
APPSER1_07015	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APPSER1_07020	ENOG4105VFK	BolA family
APPSER1_07030	ENOG4105E3I	toluene tolerance
APPSER1_07035	ENOG4107PE3	Mammalian cell entry related domain protein
APPSER1_07040	ENOG4105CY3	ABC transporter, permease
APPSER1_07045	ENOG4105DHJ	ABC, transporter
APPSER1_07050	ENOG4105C0H	protease
APPSER1_07055	ENOG4105ECP	epimerase
APPSER1_07075	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APPSER1_07085	ENOG4105EYM	Major Facilitator superfamily
APPSER1_07090	ENOG4105CMR	udp-glucose 4-epimerase
APPSER1_07115	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
APPSER1_07130	ENOG4105D2S	major facilitator superfamily
APPSER1_07135	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
APPSER1_07140	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
APPSER1_07145	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
APPSER1_07150	ENOG4107RK2	ADP-ribose diphosphatase NudE
APPSER1_07155	ENOG4105VEJ	Heat shock protein
APPSER1_07165	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
APPSER1_07170	ENOG4105DBV	ornithine carbamoyltransferase
APPSER1_07175	ENOG4105C5B	carbamate kinase
APPSER1_07180	ENOG4105C5Y	PTS System
APPSER1_07185	ENOG4107T0D	ABC, transporter
APPSER1_07190	ENOG4106SMU	thiamine transporter membrane protein
APPSER1_07195	ENOG4105KZ7	phosphocarrier protein hpr
APPSER1_07200	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
APPSER1_07205	ENOG4105C5Y	PTS System
APPSER1_07215	ENOG4105C4R	Atp-dependent dna helicase
APPSER1_07220	ENOG4107RSS	Hydrogenase accessory protein HypB
APPSER1_07225	ENOG4105CQS	hydrogenase expression formation protein HypD
APPSER1_07230	ENOG4105C45	hydrogenase expression formation protein (HypE)
APPSER1_07235	ENOG4105C8H	hydrogenase maturation protein Hypf
APPSER1_07240	ENOG4105E3S	small subunit
APPSER1_07245	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
APPSER1_07250	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
APPSER1_07255	ENOG4105DPX	Hydrogenase, large subunit
APPSER1_07260	ENOG4108USZ	hydrogenase
APPSER1_07265	ENOG4108WGS	hydrogenase 2-specific chaperone
APPSER1_07310	ENOG4108JA2	transcriptioN-repair coupling factor
APPSER1_07315	ENOG4105CD8	aminopeptidase N
APPSER1_07320	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
APPSER1_07325	ENOG4107ZVW	dihydroneopterin aldolase
APPSER1_07330	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
APPSER1_07335	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
APPSER1_07340	ENOG4105CAK	Cell division ATP-binding protein ftsE
APPSER1_07345	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APPSER1_07350	ENOG4106H78	methyltransferase
APPSER1_07355	ENOG4105XW2	UPF0263 protein
APPSER1_07360	ENOG4107UWN	reductase
APPSER1_07370	ENOG4105DMR	ABC, transporter
APPSER1_07375	ENOG4105GBT	ABC transporter
APPSER1_07380	ENOG4106PMH	Extracellular solute-binding protein family 3
APPSER1_07385	ENOG4105E5Z	arginine transporter ATP-binding subunit
APPSER1_07390	ENOG4108V1U	phospholipid-binding protein
APPSER1_07400	ENOG4105KDP	XRE family
APPSER1_07410	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
APPSER1_07415	ENOG4108BPE	-transporting atpase
APPSER1_07420	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
APPSER1_07425	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
APPSER1_07430	ENOG41082RQ	UPF0102 protein
APPSER1_07435	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
APPSER1_07440	ENOG4105W4M	Transport-associated protein
APPSER1_07465	ENOG4105DA4	cytochrome c-type biogenesis protein
APPSER1_07475	ENOG4105X3C	heme exporter protein
APPSER1_07480	ENOG41060IM	Heme exporter protein
APPSER1_07485	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
APPSER1_07490	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
APPSER1_07495	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
APPSER1_07535	ENOG4107QSA	Oxaloacetate decarboxylase
APPSER1_07540	ENOG4105D9Q	decarboxylase (Beta subunit)
APPSER1_07545	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
APPSER1_07550	ENOG4105CA0	peroxidase
APPSER1_07555	ENOG4105VZ9	UPF0235 protein
APPSER1_07560	ENOG4108VIA	integral membrane protein
APPSER1_07565	ENOG41090ED	Protein with unknown function (DUF469)
APPSER1_07570	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
APPSER1_07575	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APPSER1_07580	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
APPSER1_07585	ENOG4105VGS	50s ribosomal protein l32
APPSER1_07590	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
APPSER1_07595	ENOG4106KVJ	cytochrome C assembly protein
APPSER1_07600	ENOG4108JU6	CBS domain protein
APPSER1_07605	ENOG4105C8J	)-transporter
APPSER1_07615	ENOG4108EQA	pts system
APPSER1_07620	ENOG4105ETZ	PTS System
APPSER1_07625	ENOG4105F3R	pts system mannose fructose sorbose family iid
APPSER1_07630	ENOG4108NK4	UPF0266 membrane protein
APPSER1_07635	ENOG4105EIP	mannose-6-phosphate isomerase
APPSER1_07645	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
APPSER1_07650	ENOG4108JJA	ABC, transporter
APPSER1_07655	ENOG4107V48	Hemolysin-type calcium-binding
APPSER1_07660	ENOG41090Q8	at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP
APPSER1_07665	ENOG4105C4Y	ABC transporter
APPSER1_07675	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APPSER1_07680	ENOG4105DFU	Cell wall formation (By similarity)
APPSER1_07695	ENOG4105EHV	domain protein
APPSER1_07700	ENOG4105C5Q	Transcriptional regulator
APPSER1_07705	ENOG4105EJ2	Transcriptional regulator
APPSER1_07710	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APPSER1_07715	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
APPSER1_07725	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APPSER1_07730	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APPSER1_07735	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
APPSER1_07740	ENOG4105VCC	30S ribosomal protein S21
APPSER1_07745	ENOG4105D3Q	Sugar transferase
APPSER1_07750	ENOG4108KBE	Glycosyl transferase, family 2
APPSER1_07755	ENOG4105H63	Glycosyl transferase, family 2
APPSER1_07780	ENOG4105EY8	ABC transporter
APPSER1_07785	ENOG4105MFV	ABC-2 type transporter
APPSER1_07790	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APPSER1_07800	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
APPSER1_07805	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
APPSER1_07810	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
APPSER1_07815	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
APPSER1_07820	ENOG4108R96	Methyltransferase, YaeB family
APPSER1_07830	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APPSER1_07835	ENOG4108YZY	peptidylprolyl cis-trans isomerase
APPSER1_07840	ENOG4105C7B	Threonine dehydratase
APPSER1_07845	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
APPSER1_07850	ENOG4105E66	phosphoriboisomerase A
APPSER1_07855	ENOG4108JQ1	Dehydrogenase
APPSER1_07865	ENOG4105NXV	High-affinity zinc uptake system protein
APPSER1_07875	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
APPSER1_07885	ENOG4105C03	ribonuclease
APPSER1_07900	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
APPSER1_07915	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APPSER1_07920	ENOG4108BGM	Quinol dehydrogenase periplasmic component
APPSER1_07925	ENOG4105GXZ	Ferredoxin-type protein NapH
APPSER1_07930	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
APPSER1_07935	ENOG4105CUW	cytochrome C-TYPE protein
APPSER1_07945	ENOG4105KA0	thioesterase Superfamily protein
APPSER1_07950	ENOG4105CQB	FAD linked oxidase domain protein
APPSER1_07955	ENOG4105W44	ompa motb domain protein
APPSER1_07960	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
APPSER1_07965	ENOG4105C2J	ABC transporter
APPSER1_07970	ENOG4108HWV	)-transporter
APPSER1_07995	ENOG4108IQE	Amp-dependent synthetase and ligase
APPSER1_08000	ENOG4107QM2	Aldo Keto reductase
APPSER1_08005	ENOG4105KZW	UPF0381 protein
APPSER1_08010	ENOG4105CIC	tryptophan-specific transport protein
APPSER1_08020	ENOG4105D9M	gamma-glutamylcysteine synthetase
APPSER1_08030	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APPSER1_08060	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
APPSER1_08065	ENOG4108UBT	opacity-associated protein
APPSER1_08075	ENOG4105XA0	heptosyltransferase ii
APPSER1_08080	ENOG4105D16	lipopolysaccharide heptosyltransferase i
APPSER1_08085	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
APPSER1_08090	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
APPSER1_08095	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APPSER1_08100	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APPSER1_08125	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
APPSER1_08135	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
APPSER1_08140	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
APPSER1_08155	ENOG4105VUC	UPF0237 protein
APPSER1_08160	ENOG4105C2I	pirin domain protein
APPSER1_08165	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
APPSER1_08180	ENOG4105EM2	membrane
APPSER1_08185	ENOG4108Z5K	methylglyoxal synthase
APPSER1_08190	ENOG4105D98	threonine synthase
APPSER1_08200	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
APPSER1_08210	ENOG4107YB6	acetyltransferase, (GNAT) family
APPSER1_08215	ENOG4105MYG	DNA polymerase iii, chi subunit
APPSER1_08220	ENOG4108WZM	domain protein
APPSER1_08230	ENOG4107YZP	Rhodanese domain protein
APPSER1_08235	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
APPSER1_08240	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
APPSER1_08245	ENOG4105D7W	serine acetyltransferase
APPSER1_08250	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APPSER1_08275	ENOG4105CS9	pantothenic acid kinase
APPSER1_08280	ENOG4107QX9	Thiol disulfide interChange protein
APPSER1_08285	ENOG4108M1T	Cytochrome c-type biogenesis protein
APPSER1_08290	ENOG4108M1T	Cytochrome c-type biogenesis protein
APPSER1_08295	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
APPSER1_08300	ENOG4108YZA	Nitrogen regulatory protein pii
APPSER1_08305	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
APPSER1_08310	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
APPSER1_08315	ENOG410863D	Flavinator of succinate dehydrogenase
APPSER1_08325	ENOG4105D4P	Coproporphyrinogen iii oxidase
APPSER1_08330	ENOG4108K3A	Glutathione S-transferase
APPSER1_08335	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
APPSER1_08345	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
APPSER1_08350	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
APPSER1_08355	ENOG4105E33	succinate dehydrogenase
APPSER1_08360	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
APPSER1_08365	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
APPSER1_08370	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
APPSER1_08375	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
APPSER1_08390	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
APPSER1_08395	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APPSER1_08400	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APPSER1_08415	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
APPSER1_08420	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
APPSER1_08430	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APPSER1_08490	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
APPSER1_08495	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
APPSER1_08505	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
APPSER1_08510	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
APPSER1_08515	ENOG4105EGZ	biosynthesis protein
APPSER1_08520	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APPSER1_08530	ENOG4108IJ1	Dehydrogenase
APPSER1_08535	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
APPSER1_08545	ENOG4105ESV	Glycosyl transferase, family 4
APPSER1_08560	ENOG4105CJR	Integral membrane protein (MviN
APPSER1_08565	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
APPSER1_08570	ENOG4105C1A	potassium transporter peripheral membrane
APPSER1_08575	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
APPSER1_08580	ENOG4105EM7	Selenocysteine-specific translation elongation factor
APPSER1_08595	ENOG4105QTB	Flavodoxin
APPSER1_08605	ENOG4105CMG	Carbohydrate kinase
APPSER1_08620	ENOG4108MVK	Receptor
APPSER1_08630	ENOG4105M8F	Biopolymer transport protein exbD tolR
APPSER1_08645	ENOG4105DWU	Membrane
APPSER1_08655	ENOG4105DG4	malate L-lactate dehydrogenase
APPSER1_08660	ENOG4105MJ9	esterase
APPSER1_08695	ENOG4107VDP	teichoic acid biosynthesis
APPSER1_08725	ENOG4105DKW	ABC transporter
APPSER1_08740	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
APPSER1_08745	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
APPSER1_08750	ENOG4108RR8	protoporphyrinogen oxidase
APPSER1_08755	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
APPSER1_08760	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
APPSER1_08765	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
APPSER1_08775	ENOG4105DZ1	carboxypeptidase
APPSER1_08785	ENOG4105CNI	cell division protein FtsW
APPSER1_08790	ENOG4105CJN	penicillin-binding protein
APPSER1_08795	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
APPSER1_08800	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
APPSER1_08815	ENOG4105E5Q	amino acid AbC transporter
APPSER1_08820	ENOG4105CEM	UPF0597 protein
APPSER1_08825	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
APPSER1_08830	ENOG410814C	multidrug resistance protein
APPSER1_08835	ENOG4105KZW	UPF0381 protein
APPSER1_08855	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
APPSER1_08860	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
APPSER1_08865	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
APPSER1_08875	ENOG4105CQM	Urea amidohydrolase subunit alpha
APPSER1_08885	ENOG4108YZ9	Urea amidohydrolase subunit gamma
APPSER1_08895	ENOG4108JJB	ABC transporter
APPSER1_08905	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
APPSER1_08910	ENOG4108A51	
APPSER1_08915	ENOG4105UZ0	ABC-type Co2 transport system, periplasmic component
APPSER1_08920	ENOG4108M0I	Transcriptional regulator
APPSER1_08930	ENOG4107QWE	)-transporter
APPSER1_08935	ENOG4105E61	Mannitol repressor protein
APPSER1_08945	ENOG4105CTS	PTS system mannitol-specific
APPSER1_08950	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APPSER1_08955	ENOG410804X	Transcriptional regulator
APPSER1_08970	ENOG4106YJS	accessory processing protein
APPSER1_08980	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
APPSER1_08990	ENOG4105VRX	Protein slyX homolog
APPSER1_08995	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APPSER1_09000	ENOG4105WWK	YheO domain protein
APPSER1_09005	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
APPSER1_09010	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
APPSER1_09045	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APPSER1_09050	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APPSER1_09055	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APPSER1_09060	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APPSER1_09070	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APPSER1_09085	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
APPSER1_09090	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
APPSER1_09095	ENOG410667J	hydrolase
APPSER1_09100	ENOG4105EAB	amino acid AbC transporter
APPSER1_09105	ENOG4105K5B	UPF0225 protein
APPSER1_09115	ENOG4105F3R	pts system mannose fructose sorbose family iid
APPSER1_09120	ENOG4105ETZ	PTS System
APPSER1_09125	ENOG4108EQA	pts system
APPSER1_09130	ENOG4105C6Z	Gluconate
APPSER1_09135	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
APPSER1_09140	ENOG4105DIQ	Transcriptional regulator
APPSER1_09145	ENOG4105ETE	Transcriptional regulator (LacI family
APPSER1_09160	ENOG4105CNN	ABC, transporter
APPSER1_09165	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
APPSER1_09170	ENOG4108RVA	ribokinase
APPSER1_09175	ENOG4107QY8	reductase
APPSER1_09180	ENOG4105QAX	Iron-sulfur
APPSER1_09185	ENOG4107KGK	dmso reductase anchor subunit
APPSER1_09190	ENOG4108NEM	leader-binding protein dmsD
APPSER1_09195	ENOG4105N1P	Ferredoxin-type protein
APPSER1_09215	ENOG4108ETH	Formylglycinamide ribotide synthetase
APPSER1_09220	ENOG4107EDW	L-fucose operon activator
APPSER1_09225	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
APPSER1_09230	ENOG4105CMG	Carbohydrate kinase
APPSER1_09235	ENOG4105NWF	RbsD or FucU transport
APPSER1_09240	ENOG4107W7X	Aldolase
APPSER1_09245	ENOG4105EDR	glucose galactose transporter
APPSER1_09250	ENOG4105C0A	alcohol dehydrogenase
APPSER1_09255	ENOG4105R3P	Inner membrane protein yagU
APPSER1_09260	ENOG4105E5Q	amino acid AbC transporter
APPSER1_09270	ENOG4105CDA	abc transporter atp-binding protein
APPSER1_09275	ENOG4105CT1	(ABC) transporter
APPSER1_09280	ENOG4105E12	capsule polysaccharide
APPSER1_09320	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
APPSER1_09325	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
APPSER1_09330	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APPSER1_09355	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
APPSER1_09365	ENOG4105C79	DNA protecting protein DprA
APPSER1_09370	ENOG4105EPD	Oligopeptide transporter, Opt family
APPSER1_09385	ENOG4105PM1	preprotein translocase subunit SecE
APPSER1_09390	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
APPSER1_09395	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
APPSER1_09400	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
APPSER1_09405	ENOG4108VZM	50s ribosomal protein L10
APPSER1_09410	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
APPSER1_09490	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
APPSER1_09495	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
APPSER1_09505	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
APPSER1_09510	ENOG4105CEN	a g-specific adenine glycosylase
APPSER1_09515	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
APPSER1_09520	ENOG4105E4C	Lytic transglycosylase catalytic
APPSER1_09545	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APPSER1_09550	ENOG4105CGH	5'-nucleotidase
APPSER1_09555	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
APPSER1_09560	ENOG4105C0P	Mg chelatase subunit ChlI
APPSER1_09565	ENOG4106IIQ	Outer membrane lipoprotein
APPSER1_09570	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
APPSER1_09575	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
APPSER1_09585	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
APPSER1_09590	ENOG4105EVU	fructokinase
APPSER1_09595	ENOG4108MB0	N-acetylneuraminate lyase
APPSER1_09600	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
APPSER1_09605	ENOG4105CE4	GlcNAc 6-P deacetylase
APPSER1_09610	ENOG4105C9Q	fumarate hydratase class II
APPSER1_09625	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
APPSER1_09630	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
APPSER1_09635	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
APPSER1_09640	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APPSER1_09645	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
APPSER1_09650	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
APPSER1_09655	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
APPSER1_09660	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
APPSER1_09665	ENOG41083MP	50s ribosomal protein l29
APPSER1_09670	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
APPSER1_09680	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
APPSER1_09685	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APPSER1_09690	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APPSER1_09695	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
APPSER1_09700	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
APPSER1_09705	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
APPSER1_09710	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
APPSER1_09715	ENOG4105VPB	50S ribosomal protein L30
APPSER1_09720	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
APPSER1_09725	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
APPSER1_09735	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APPSER1_09740	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
APPSER1_09745	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
APPSER1_09750	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APPSER1_09760	ENOG4105K5M	30s ribosomal protein S16
APPSER1_09765	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
APPSER1_09770	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
APPSER1_09775	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
APPSER1_09780	ENOG4105EZE	Cupin 4 family protein
APPSER1_09785	ENOG4105S10	periplasmic binding protein
APPSER1_09790	ENOG4105EHG	Permease protein
APPSER1_09795	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
APPSER1_09820	ENOG4108J2R	molybdopterin oxidoreductase
APPSER1_09835	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
APPSER1_09860	ENOG4105WD1	Membrane
APPSER1_09865	ENOG4105K64	Glycosyl transferase, family 2
APPSER1_09870	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
APPSER1_09875	ENOG4105RX8	Protein of unknown function (DUF1523)
APPSER1_09880	ENOG4105F8V	Hydrolase, tatD family
APPSER1_09890	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APPSER1_09895	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
APPSER1_09900	ENOG4107ZJM	MltA-interacting protein MipA
APPSER1_09905	ENOG4107QRG	dna polymerase iii
APPSER1_09910	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
APPSER1_09915	ENOG4105HHA	aminodeoxychorismate lyase
APPSER1_09935	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APPSER1_09940	ENOG4105DJV	ribulose-phosphate 3-epimerase
APPSER1_09945	ENOG4105NRA	50s ribosomal protein l31 type b
APPSER1_09950	ENOG4105YK5	50S ribosomal protein L36
APPSER1_09955	ENOG4105BZ4	penicillin-binding protein
APPSER1_09960	ENOG4108IPT	Naphthoate synthase
APPSER1_09965	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APPSER1_09975	ENOG4105CB5	ATP-dependent DNA helicase recG
APPSER1_09990	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APPSER1_10000	ENOG4108WQI	RNA Polymerase
APPSER1_10005	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
APPSER1_10010	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
APPSER1_10015	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APPSER1_10020	ENOG4105CXY	transporter
APPSER1_10040	ENOG4105CU9	asparagine synthetase A
APPSER1_10045	ENOG4108VVK	transcriptional Regulator, AsnC
APPSER1_10050	ENOG4108I5U	Uridine phosphorylase
APPSER1_10055	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
APPSER1_10085	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
APPSER1_10090	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APPSER1_10115	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
APPSER1_10120	ENOG4108I5D	sulfate abc transporter
APPSER1_10125	ENOG4105ECW	sulfate abc transporter
APPSER1_10130	ENOG4108IJ6	ABC transporter
APPSER1_10140	ENOG4105DMF	Dehydrogenase
APPSER1_10145	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
APPSER1_10150	ENOG4105D4A	Cell wall formation (By similarity)
APPSER1_10160	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
APPSER1_10165	ENOG4105H2K	paraquat-inducible protein a
APPSER1_10170	ENOG4108KS2	transglutaminase domain protein
APPSER1_10180	ENOG410681U	heavy metal transport detoxification protein
APPSER1_10185	ENOG4107QW4	alcohol dehydrogenase
APPSER1_10190	ENOG4105EMY	transcriptional regulator
APPSER1_10195	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
APPSER1_10200	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APPSER1_10205	ENOG4108ST3	glycosyltransferase
APPSER1_10210	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
APPSER1_10215	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APPSER1_10220	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
APPSER1_10230	ENOG4108Z33	Thiol disulfide Interchange Protein
APPSER1_10240	ENOG41063M6	Cell Division Protein
APPSER1_10240	ENOG41063M6	Cell Division Protein
APPSER1_10255	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APPSER1_10260	ENOG4105KUZ	arsenate reductase
APPSER1_10270	ENOG4105EEI	dihydropteroate synthase
APPSER1_10275	ENOG4105EI2	Pseudouridine synthase
APPSER1_10290	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APPSER1_10300	ENOG4107QXK	peptidase
APPSER1_10305	ENOG4105DSY	exodeoxyribonuclease V, gamma
APPSER1_10330	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
APPSER1_10335	ENOG4105DAN	ATP-dependent protease
APPSER1_10340	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
APPSER1_10345	ENOG4105C31	Tryptophanyl-tRNA synthetase
APPSER1_10365	ENOG4105HF0	Membrane
APPSER1_10380	ENOG4105F0N	pyrophosphate phospho-hydrolase
APPSER1_10390	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
APPSER1_10395	ENOG4105TMB	Formate nitrite transporter
APPSER1_10420	ENOG4105CFG	Acts as a chaperone (By similarity)
APPSER1_10425	ENOG4105CMG	Carbohydrate kinase
APPSER1_10430	ENOG4105C93	Xylose Isomerase
APPSER1_10435	ENOG4105DFW	ABC transporter
APPSER1_10440	ENOG4105C2J	ABC transporter
APPSER1_10445	ENOG4108HWW	ABC transporter
APPSER1_10450	ENOG4105T16	Transcriptional regulator (AraC family)
APPSER1_10455	ENOG4105C9K	Endothelin-converting enzyme 1
APPSER1_10465	ENOG4108IA2	Sodium pantothenate symporter
APPSER1_10470	ENOG4105RG0	Membrane
APPSER1_10475	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
APPSER1_10480	ENOG410903C	(LipO)protein
APPSER1_10485	ENOG4105DSB	aldose 1-epimerase
APPSER1_10500	ENOG4107BJW	polysaccharide deacetylase
APPSER1_10505	ENOG4105CND	Glycosyl transferase, family 2
APPSER1_10515	ENOG4105CP7	Triose-phosphate isomerase
APPSER1_10520	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
APPSER1_10525	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
APPSER1_10530	ENOG4108UM1	dedA family
APPSER1_10545	ENOG4108K5P	(LipO)protein
APPSER1_10550	ENOG4108R3E	Dna-3-methyladenine glycosylase i
APPSER1_10560	ENOG4108P2H	Inner membrane protein YjiG
APPSER1_10565	ENOG41074DU	domain protein
APPSER1_10570	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
APPSER1_10575	ENOG4105VG0	50S ribosomal protein l34
APPSER1_10580	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
APPSER1_10585	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
APPSER1_10590	ENOG4105C5F	glutamine synthetase
APPSER1_10595	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
APPSER1_10600	ENOG41087AY	ADP-Ribose pyrophosphatase
APPSER1_10605	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
APPSER1_10610	ENOG4105W8Z	4'-phosphopantetheinyl transferase
APPSER1_10630	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
APPSER1_10635	ENOG4107S2Z	UPF0761 membrane protein
APPSER1_10640	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
APPSER1_10675	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
APPSER1_10680	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
APPSER1_10685	ENOG4108URH	decarboxylase
APPSER1_10690	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
APPSER1_10695	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
APPSER1_10700	ENOG4105YP7	UPF0270 protein
APPSER1_10705	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
APPSER1_10715	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
APPSER1_10720	ENOG4105W5Q	DNA repair protein (RadC
APPSER1_10725	ENOG4105KDC	50s ribosomal protein l28
APPSER1_10730	ENOG4105W0E	50S ribosomal protein L33
APPSER1_10740	ENOG4108JPW	Aminotransferase
APPSER1_10745	ENOG4105DY8	decarboxylase
APPSER1_10750	ENOG4105KSU	Redox protein
APPSER1_10755	ENOG41066VF	YeeE YedE family protein
APPSER1_10760	ENOG4108WFC	UPF0438 protein yifE
APPSER1_10780	ENOG4107QUT	magnesium and cobalt transport protein CorA
APPSER1_10785	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APPSER1_10795	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APPSER1_10800	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
APPSER1_10805	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
APPSER1_10810	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
APPSER1_10815	ENOG4105D52	delta-aminolevulinic acid dehydratase
APPSER1_10830	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
APPSER1_10835	ENOG4105CHR	reductase
APPSER1_10840	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APPSER1_10845	ENOG4105WPN	DNA integration recombination invertion protein
APPSER1_10850	ENOG4105EAH	synthase
APPSER1_10860	ENOG4108YYH	Nadph-dependent fmn reductase
APPSER1_10865	ENOG4105MGM	doxx family
APPSER1_10870	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
APPSER1_10875	ENOG4105K46	50S ribosomal protein l27
APPSER1_10880	ENOG4105QYV	Membrane
APPSER1_10895	ENOG4105MJ2	Competence protein
APPSER1_10910	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
APPSER1_10915	ENOG4105C1J	atp-dependent rna helicase
APPSER1_10925	ENOG4105DEF	Extracellular solute-binding protein, family 5
APPSER1_10935	ENOG4106HK8	GPR1 FUN34 yaaH family protein
APPSER1_10940	ENOG4105E0A	ABC, transporter
APPSER1_10950	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
APPSER1_10975	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APPSER1_10980	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APPSER1_11000	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
APPSER1_11015	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
APPSER1_11020	ENOG4105EX9	Membrane
APPSER1_11025	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
APPSER1_11035	ENOG4105WBN	Transcriptional regulator (LacI family
APPSER1_11045	ENOG4105D7K	pfkb domain protein
APPSER1_11050	ENOG4105CEI	nitrite reductase
APPSER1_11055	ENOG4105D60	lipoprotein releasing system transmembrane protein
APPSER1_11060	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APPSER1_11065	ENOG4105D60	lipoprotein releasing system transmembrane protein
APPSER1_11070	ENOG4105C5I	Dehydrogenase
APPSER1_11080	ENOG41063JG	Transcriptional regulator
APPSER1_11085	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)