locus-tag	class	description
DDU33_00005	COG0210	DNA helicase
DDU33_00010	COG0551	DNA topoisomerase type I activity
DDU33_00015	COG0009	L-threonylcarbamoyladenylate synthase
DDU33_00020	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDU33_00020	COG1388	LysM domain
DDU33_00025	COG0802	atpase or kinase
DDU33_00040	COG1519	Transferase
DDU33_00045	COG3307	-O-antigen
DDU33_00060	COG3753	Protein conserved in bacteria
DDU33_00070	COG0492	ferredoxin-NADP+ reductase activity
DDU33_00075	COG3118	belongs to the thioredoxin family
DDU33_00085	COG0811	peptide transport
DDU33_00095	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DDU33_00100	COG5413	integral membrane protein
DDU33_00120	COG1663	tetraacyldisaccharide 4'-kinase activity
DDU33_00125	COG3177	Filamentation induced by cAMP protein fic
DDU33_00130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DDU33_00135	COG0740	serine-type endopeptidase activity
DDU33_00140	COG2166	iron-sulfur cluster assembly
DDU33_00155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDU33_00160	COG2137	regulation of response to DNA damage stimulus
DDU33_00170	COG4591	ABC-type transport system involved in lipoprotein release permease component
DDU33_00175	COG1136	(ABC) transporter
DDU33_00180	COG4591	ABC-type transport system involved in lipoprotein release permease component
DDU33_00185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDU33_00190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDU33_00195	COG2197	response regulator
DDU33_00205	COG0187	DNA topoisomerase II activity
DDU33_00210	COG2814	Major facilitator Superfamily
DDU33_00220	COG0616	signal peptide processing
DDU33_00225	COG4211	Belongs to the binding-protein-dependent transport system permease family
DDU33_00230	COG1129	ABC transporter
DDU33_00235	COG1879	ABC-type sugar transport system periplasmic component
DDU33_00240	COG3719	Belongs to the RNase T2 family
DDU33_00250	COG1252	NADH dehydrogenase
DDU33_00255	COG0525	valine-tRNA ligase activity
DDU33_00270	COG4185	zeta toxin
DDU33_00275	COG2153	protein acetylation
DDU33_00280	COG0140	phosphoribosyl-ATP diphosphatase activity
DDU33_00280	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DDU33_00290	COG0107	imidazoleglycerol-phosphate synthase activity
DDU33_00295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DDU33_00300	COG2852	Protein conserved in bacteria
DDU33_00305	COG2258	MOSC domain
DDU33_00310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DDU33_00325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DDU33_00325	COG0131	Imidazoleglycerol-phosphate dehydratase
DDU33_00335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDU33_00355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDU33_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DDU33_00365	COG3107	peptidoglycan biosynthetic process
DDU33_00370	COG0792	nuclease activity
DDU33_00375	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DDU33_00390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDU33_00395	COG0842	Transport permease protein
DDU33_00395	COG1129	ABC transporter
DDU33_00400	COG0842	Transport permease protein
DDU33_00405	COG1538	Outer membrane efflux protein
DDU33_00420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DDU33_00425	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DDU33_00430	COG1561	YicC-like family, N-terminal region
DDU33_00435	COG0354	folic acid binding
DDU33_00440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDU33_00445	COG5007	Belongs to the BolA IbaG family
DDU33_00455	COG2854	intermembrane phospholipid transfer
DDU33_00460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DDU33_00465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DDU33_00470	COG1127	ABC transporter
DDU33_00480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDU33_00485	COG0859	PFAM glycosyl transferase family 9
DDU33_00490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DDU33_00495	COG1605	Chorismate mutase
DDU33_00495	COG0287	Prephenate dehydrogenase
DDU33_00500	COG5633	Lipoprotein
DDU33_00505	COG0537	adenosine 5'-monophosphoramidase activity
DDU33_00515	COG1162	GTPase activity
DDU33_00520	COG0583	DNA-binding transcription factor activity
DDU33_00530	COG0251	oxidation-reduction process
DDU33_00535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDU33_00540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DDU33_00545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDU33_00550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DDU33_00555	COG0151	Belongs to the GarS family
DDU33_00565	COG2965	DNA replication, synthesis of RNA primer
DDU33_00585	COG0009	L-threonylcarbamoyladenylate synthase
DDU33_00590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DDU33_00600	COG4545	Glutaredoxin-related protein
DDU33_00605	COG1794	racemase activity, acting on amino acids and derivatives
DDU33_00610	COG3759	membrane
DDU33_00615	COG2814	Major facilitator Superfamily
DDU33_00620	COG0363	glucosamine-6-phosphate deaminase activity
DDU33_00625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DDU33_00630	COG1218	3'(2'),5'-bisphosphate nucleotidase
DDU33_00635	COG0494	nUDIX hydrolase
DDU33_00640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DDU33_00645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DDU33_00670	COG2095	MarC family integral membrane protein
DDU33_00675	COG0084	hydrolase, TatD family'
DDU33_00680	COG0210	DNA helicase
DDU33_00685	COG2885	chlorophyll binding
DDU33_00685	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DDU33_00695	COG1595	DNA-templated transcription, initiation
DDU33_00705	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_00720	COG3311	Transcriptional regulator
DDU33_00745	COG3210	domain, Protein
DDU33_00745	COG3210	domain, Protein
DDU33_00750	COG2831	hemolysin activation secretion protein
DDU33_00785	COG0640	Transcriptional regulator
DDU33_00800	COG0786	glutamate:sodium symporter activity
DDU33_00820	COG0582	viral genome integration into host DNA
DDU33_00830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDU33_00835	COG2190	(PTS) system
DDU33_00840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDU33_00845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDU33_00850	COG1178	ABC-type Fe3 transport system permease component
DDU33_00855	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DDU33_00865	COG2995	paraquat-inducible protein a
DDU33_00870	COG0606	chelatase, subunit chli
DDU33_00895	COG0180	Tryptophanyl-tRNA synthetase
DDU33_00905	COG3084	Protein conserved in bacteria
DDU33_00910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDU33_00920	COG2197	response regulator
DDU33_00925	COG3851	Histidine kinase
DDU33_00930	COG2271	Major facilitator Superfamily
DDU33_00935	COG1482	cell wall glycoprotein biosynthetic process
DDU33_00940	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DDU33_00940	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DDU33_00945	COG0742	ribosomal rna small subunit methyltransferase
DDU33_00950	COG1876	peptidase activity
DDU33_00955	COG1858	cytochrome C peroxidase
DDU33_00970	COG1393	Belongs to the ArsC family
DDU33_00975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DDU33_00980	COG0564	pseudouridine synthase activity
DDU33_00985	COG0668	transmembrane transport
DDU33_00990	COG3005	denitrification pathway
DDU33_00995	COG3043	anaerobic respiration
DDU33_01000	COG0348	domain, Protein
DDU33_01005	COG0437	4 iron, 4 sulfur cluster binding
DDU33_01010	COG0243	molybdopterin cofactor binding
DDU33_01015	COG3062	negative regulation of establishment of protein localization
DDU33_01025	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDU33_01030	COG4942	peptidase
DDU33_01030	COG1388	LysM domain
DDU33_01045	COG1238	metal cluster binding
DDU33_01050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DDU33_01060	COG0012	GTP binding
DDU33_01070	COG0259	pyridoxamine-phosphate oxidase activity
DDU33_01080	COG0513	Belongs to the DEAD box helicase family
DDU33_01085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DDU33_01090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDU33_01105	COG1289	transmembrane transporter activity
DDU33_01110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDU33_01110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDU33_01115	COG3715	PTS system
DDU33_01120	COG3716	PTS system mannose fructose sorbose family IID component
DDU33_01135	COG0561	phosphatase activity
DDU33_01140	COG2271	Major facilitator Superfamily
DDU33_01145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DDU33_01150	COG4145	pantothenate transmembrane transporter activity
DDU33_01155	COG3924	membrane
DDU33_01160	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
DDU33_01165	COG2853	Lipoprotein
DDU33_01175	COG0748	coenzyme F420 binding
DDU33_01180	COG3721	Heme iron utilization protein
DDU33_01185	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DDU33_01190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDU33_01195	COG4558	Periplasmic binding protein
DDU33_01205	COG0497	DNA recombination
DDU33_01215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DDU33_01225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DDU33_01225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DDU33_01230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DDU33_01245	COG1309	transcriptional regulator
DDU33_01255	COG1442	glycosyl transferase family 8
DDU33_01260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDU33_01265	COG2003	Belongs to the UPF0758 family
DDU33_01270	COG0772	Belongs to the SEDS family
DDU33_01275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DDU33_01285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDU33_01295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDU33_01300	COG0768	penicillin binding
DDU33_01305	COG3116	cell division
DDU33_01310	COG0275	rRNA processing
DDU33_01315	COG0557	exoribonuclease II activity
DDU33_01325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DDU33_01330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DDU33_01395	COG0316	Belongs to the HesB IscA family
DDU33_01400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDU33_01410	COG1720	tRNA m6t6A37 methyltransferase activity
DDU33_01415	COG1575	Belongs to the MenA family. Type 1 subfamily
DDU33_01420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DDU33_01425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DDU33_01430	COG0494	nUDIX hydrolase
DDU33_01445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DDU33_01470	COG1490	D-aminoacyl-tRNA deacylase activity
DDU33_01480	COG3085	chromosome segregation
DDU33_01495	COG0598	Magnesium transport protein CorA
DDU33_01500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDU33_01505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDU33_01510	COG0805	protein transport
DDU33_01520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DDU33_01525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDU33_01535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DDU33_01555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DDU33_01560	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_01565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DDU33_01570	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DDU33_01575	COG2731	YhcH YjgK YiaL family protein
DDU33_01580	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DDU33_01585	COG1414	Transcriptional regulator
DDU33_01590	COG0490	domain, Protein
DDU33_01590	COG0471	metal ion transport
DDU33_01605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DDU33_01610	COG2226	methyltransferase
DDU33_01615	COG2830	Protein of unknown function (DUF452)
DDU33_01625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDU33_01640	COG4545	Glutaredoxin-related protein
DDU33_01670	COG2850	peptidyl-arginine hydroxylation
DDU33_01685	COG3468	outer membrane autotransporter barrel domain protein
DDU33_01695	COG0431	NADPH-dependent FMN reductase
DDU33_01700	COG2927	DNA polymerase III (CHI subunit)
DDU33_01710	COG1652	LysM domain
DDU33_01715	COG0544	peptidyl-prolyl cis-trans isomerase activity
DDU33_01720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDU33_01730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDU33_01735	COG1045	serine acetyltransferase
DDU33_01740	COG2832	Protein of unknown function (DUF454)
DDU33_01750	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DDU33_01755	COG1070	Carbohydrate kinase
DDU33_01760	COG2115	Belongs to the xylose isomerase family
DDU33_01765	COG2814	Major facilitator Superfamily
DDU33_01765	COG0477	Major facilitator Superfamily
DDU33_01770	COG1609	Transcriptional regulator
DDU33_01770	COG2207	Transcriptional regulator
DDU33_01780	COG0084	hydrolase, TatD family'
DDU33_01785	COG0676	glucose-6-phosphate 1-epimerase activity
DDU33_01790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDU33_01800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDU33_01820	COG1840	ABC-type Fe3 transport system, periplasmic component
DDU33_01830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDU33_01835	COG0254	rRNA binding
DDU33_01840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDU33_01845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDU33_01850	COG0439	Biotin carboxylase
DDU33_01855	COG0511	ligase activity, forming carbon-carbon bonds
DDU33_01860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDU33_01890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDU33_01910	COG0521	Mo-molybdopterin cofactor biosynthetic process
DDU33_01915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDU33_01920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDU33_01925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDU33_01930	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
DDU33_01945	COG0716	FMN binding
DDU33_01955	COG1921	L-seryl-tRNASec selenium transferase activity
DDU33_01985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDU33_01990	COG2502	aspartate--ammonia ligase
DDU33_01995	COG1522	sequence-specific DNA binding
DDU33_02000	COG0470	DNA polymerase III
DDU33_02005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DDU33_02010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDU33_02045	COG0228	four-way junction DNA binding
DDU33_02050	COG0673	inositol 2-dehydrogenase activity
DDU33_02055	COG4178	(ABC) transporter
DDU33_02060	COG0612	Peptidase, M16
DDU33_02080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDU33_02090	COG0202	RNA polymerase activity
DDU33_02095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DDU33_02105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DDU33_02115	COG0201	protein transport
DDU33_02120	COG0200	Binds to the 23S rRNA
DDU33_02125	COG1841	ribosomal large subunit assembly
DDU33_02130	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DDU33_02135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DDU33_02145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DDU33_02150	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDU33_02160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DDU33_02175	COG0728	peptidoglycan biosynthetic process
DDU33_02185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DDU33_02190	COG0517	IMP dehydrogenase activity
DDU33_02190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DDU33_02195	COG1929	Belongs to the glycerate kinase type-1 family
DDU33_02200	COG2610	gluconate transmembrane transporter activity
DDU33_02205	COG3835	regulator
DDU33_02215	COG0019	diaminopimelate decarboxylase activity
DDU33_02230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DDU33_02245	COG0741	lytic transglycosylase activity
DDU33_02250	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DDU33_02255	COG1194	a g-specific adenine glycosylase
DDU33_02260	COG0346	lactoylglutathione lyase activity
DDU33_02290	COG1022	Amp-dependent synthetase and ligase
DDU33_02305	COG0545	Peptidyl-prolyl cis-trans isomerase
DDU33_02315	COG1045	serine acetyltransferase
DDU33_02325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDU33_02330	COG0235	Class ii aldolase
DDU33_02335	COG3623	hexulose-6-phosphate isomerase
DDU33_02360	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DDU33_02370	COG2264	protein methyltransferase activity
DDU33_02375	COG2369	cell adhesion
DDU33_02380	COG3620	sequence-specific DNA binding
DDU33_02405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DDU33_02410	COG0321	lipoyl(octanoyl) transferase activity
DDU33_02415	COG2921	Belongs to the UPF0250 family
DDU33_02420	COG1686	Belongs to the peptidase S11 family
DDU33_02425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DDU33_02430	COG0772	Belongs to the SEDS family
DDU33_02435	COG0768	penicillin binding
DDU33_02440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DDU33_02445	COG0799	negative regulation of ribosome biogenesis
DDU33_02455	COG0625	glutathione transferase activity
DDU33_02465	COG3550	peptidyl-serine autophosphorylation
DDU33_02470	COG3550	peptidyl-serine autophosphorylation
DDU33_02505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DDU33_02540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DDU33_02545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDU33_02555	COG2900	Belongs to the SlyX family
DDU33_02560	COG0545	Peptidyl-prolyl cis-trans isomerase
DDU33_02565	COG2964	Protein conserved in bacteria
DDU33_02570	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DDU33_02580	COG2168	tRNA wobble position uridine thiolation
DDU33_02585	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DDU33_02590	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DDU33_02595	COG1053	succinate dehydrogenase
DDU33_02600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DDU33_02605	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DDU33_02620	COG1970	mechanosensitive ion channel activity
DDU33_02625	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
DDU33_02630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDU33_02635	COG1739	Uncharacterized protein family UPF0029
DDU33_02660	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DDU33_02665	COG0830	nickel cation binding
DDU33_02695	COG0831	urea catabolic process
DDU33_02705	COG1122	ATPase activity
DDU33_02710	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DDU33_02715	COG0310	cobalt ion transport
DDU33_02720	COG0310	cobalt ion transport
DDU33_02725	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
DDU33_02735	COG0583	DNA-binding transcription factor activity
DDU33_02745	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDU33_02755	COG4221	oxidoreductase activity
DDU33_02765	COG0110	maltose O-acetyltransferase activity
DDU33_02785	COG3384	dioxygenase
DDU33_02810	COG1373	ATPase (AAA superfamily
DDU33_02815	COG0583	DNA-binding transcription factor activity
DDU33_02835	COG1902	pentaerythritol trinitrate reductase activity
DDU33_02845	COG0583	DNA-binding transcription factor activity
DDU33_02870	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDU33_02870	COG1902	pentaerythritol trinitrate reductase activity
DDU33_02890	COG0477	Major facilitator Superfamily
DDU33_02925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DDU33_02930	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DDU33_02945	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_02955	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_02975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DDU33_03015	COG2910	NAD(P)H-binding
DDU33_03025	COG1902	pentaerythritol trinitrate reductase activity
DDU33_03025	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDU33_03035	COG2207	Transcriptional regulator
DDU33_03055	COG1764	response to oxidative stress
DDU33_03070	COG0798	PFAM Bile acid sodium symporter
DDU33_03085	COG1733	regulation of RNA biosynthetic process
DDU33_03095	COG0445	tRNA wobble uridine modification
DDU33_03100	COG3012	SEC-C Motif Domain Protein
DDU33_03110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDU33_03125	COG1305	Transglutaminase-like
DDU33_03135	COG2608	mercury ion transmembrane transporter activity
DDU33_03140	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DDU33_03145	COG1609	Transcriptional regulator
DDU33_03150	COG3265	gluconokinase activity
DDU33_03155	COG2610	gluconate transmembrane transporter activity
DDU33_03160	COG0765	amino acid transport
DDU33_03165	COG1126	abc transporter atp-binding protein
DDU33_03170	COG3691	Protein conserved in bacteria
DDU33_03190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DDU33_03195	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDU33_03200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DDU33_03205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDU33_03210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DDU33_03235	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDU33_03240	COG1879	ABC-type sugar transport system periplasmic component
DDU33_03245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDU33_03280	COG0252	asparaginase activity
DDU33_03295	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DDU33_03305	COG3477	response to acidic pH
DDU33_03310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDU33_03315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDU33_03320	COG0584	glycerophosphoryl diester phosphodiesterase
DDU33_03330	COG2271	Major facilitator Superfamily
DDU33_03335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DDU33_03340	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
DDU33_03345	COG0247	lactate metabolic process
DDU33_03350	COG1012	belongs to the aldehyde dehydrogenase family
DDU33_03370	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DDU33_03375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDU33_03380	COG4771	TonB-dependent receptor
DDU33_03395	COG0758	DNA mediated transformation
DDU33_03400	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDU33_03410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDU33_03420	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DDU33_03430	COG0235	Class ii aldolase
DDU33_03440	COG1070	Carbohydrate kinase
DDU33_03445	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
DDU33_03465	COG1349	DNA-binding transcription factor activity
DDU33_03470	COG2190	(PTS) system
DDU33_03470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDU33_03470	COG1263	PTS System
DDU33_03475	COG1454	alcohol dehydrogenase
DDU33_03480	COG1879	ABC-type sugar transport system periplasmic component
DDU33_03485	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDU33_03490	COG1129	ABC transporter
DDU33_03495	COG0085	RNA polymerase activity
DDU33_03520	COG1686	Belongs to the peptidase S11 family
DDU33_03525	COG3070	regulator of competence-specific genes
DDU33_03530	COG0051	transcription antitermination factor activity, RNA binding
DDU33_03535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDU33_03540	COG0088	Forms part of the polypeptide exit tunnel
DDU33_03545	COG0089	rRNA binding
DDU33_03555	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DDU33_03565	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DDU33_03570	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DDU33_03575	COG0255	Belongs to the universal ribosomal protein uL29 family
DDU33_03580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DDU33_03585	COG0569	domain protein
DDU33_03590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DDU33_03595	COG3276	selenocysteine insertion sequence binding
DDU33_03600	COG0442	prolyl-tRNA aminoacylation
DDU33_03615	COG1349	DNA-binding transcription factor activity
DDU33_03620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDU33_03625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDU33_03635	COG0825	malonyl-CoA metabolic process
DDU33_03645	COG0204	Acyl-transferase
DDU33_03650	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DDU33_03655	COG0494	nUDIX hydrolase
DDU33_03660	COG0730	response to heat
DDU33_03670	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DDU33_03675	COG0546	phosphoglycolate phosphatase activity
DDU33_03690	COG3691	Protein conserved in bacteria
DDU33_03695	COG0814	amino acid
DDU33_03700	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
DDU33_03715	COG1442	glycosyl transferase family 8
DDU33_03715	COG1216	Glycosyl transferase, family 2
DDU33_03720	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DDU33_03725	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDU33_03730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DDU33_03735	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DDU33_03740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDU33_03745	COG3381	protein complex oligomerization
DDU33_03755	COG3005	denitrification pathway
DDU33_03770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DDU33_03790	COG1741	Belongs to the pirin family
DDU33_03815	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DDU33_03825	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DDU33_03830	COG0859	PFAM glycosyl transferase family 9
DDU33_03835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDU33_03840	COG0049	tRNA binding
DDU33_03850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDU33_03865	COG3344	reverse transcriptase
DDU33_03880	COG1555	photosystem II stabilization
DDU33_03885	COG3266	domain, Protein
DDU33_03885	COG3061	Opacity-associated protein A
DDU33_03895	COG0859	PFAM glycosyl transferase family 9
DDU33_03915	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DDU33_03925	COG4208	sulfate ABC transporter
DDU33_03930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DDU33_03940	COG3111	PFAM Bacterial OB fold (BOF) protein
DDU33_03945	COG2828	Protein conserved in bacteria
DDU33_03950	COG0471	metal ion transport
DDU33_03955	COG2188	Transcriptional regulator
DDU33_03975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDU33_03980	COG1151	hydroxylamine reductase activity
DDU33_03990	COG0174	glutamine synthetase
DDU33_04045	COG4974	Belongs to the 'phage' integrase family
DDU33_04050	COG0037	tRNA processing
DDU33_04065	COG2050	protein possibly involved in aromatic compounds catabolism
DDU33_04070	COG0277	FAD linked oxidase domain protein
DDU33_04070	COG0247	lactate metabolic process
DDU33_04080	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DDU33_04080	COG2885	chlorophyll binding
DDU33_04085	COG3120	sequence-specific DNA binding
DDU33_04090	COG1067	ATP-dependent peptidase activity
DDU33_04095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDU33_04120	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DDU33_04130	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DDU33_04130	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DDU33_04130	COG0506	proline dehydrogenase activity
DDU33_04135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDU33_04140	COG0814	amino acid
DDU33_04150	COG0443	Heat shock 70 kDa protein
DDU33_04155	COG3590	peptidase
DDU33_04170	COG2818	Glycosylase
DDU33_04180	COG1640	4-alpha-glucanotransferase
DDU33_04185	COG3833	ABC-type maltose transport systems, permease component
DDU33_04200	COG3842	ATPase activity
DDU33_04205	COG4580	involved in the transport of maltose and maltodextrins
DDU33_04220	COG0366	Alpha amylase catalytic
DDU33_04225	COG2909	trisaccharide binding
DDU33_04230	COG0058	SHG alpha-glucan phosphorylase activity
DDU33_04240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DDU33_04245	COG0594	ribonuclease P activity
DDU33_04260	COG0697	spore germination
DDU33_04265	COG0697	spore germination
DDU33_04270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DDU33_04280	COG0142	geranyltranstransferase activity
DDU33_04285	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DDU33_04290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDU33_04295	COG1028	Short-chain dehydrogenase reductase Sdr
DDU33_04300	COG1114	Component of the transport system for branched-chain amino acids
DDU33_04310	COG0076	glutamate decarboxylase activity
DDU33_04315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDU33_04325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDU33_04350	COG0849	cell division
DDU33_04360	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DDU33_04380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DDU33_04385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDU33_04390	COG2824	Alkylphosphonate utilization operon protein PhnA
DDU33_04395	COG2990	Protein conserved in bacteria
DDU33_04405	COG0762	integral membrane protein
DDU33_04410	COG3171	Protein conserved in bacteria
DDU33_04415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDU33_04420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDU33_04425	COG0416	fatty acid biosynthetic process
DDU33_04430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDU33_04435	COG1399	metal-binding, possibly nucleic acid-binding protein
DDU33_04440	COG4137	Cytochrome C assembly protein
DDU33_04445	COG4536	flavin adenine dinucleotide binding
DDU33_04450	COG0733	neurotransmitter:sodium symporter activity
DDU33_04460	COG2860	membrane
DDU33_04475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDU33_04480	COG1621	beta-fructofuranosidase activity
DDU33_04495	COG0778	Nitroreductase
DDU33_04510	COG4172	Belongs to the ABC transporter superfamily
DDU33_04515	COG0191	fructose-bisphosphate aldolase activity
DDU33_04520	COG0126	phosphoglycerate kinase activity
DDU33_04525	COG0471	metal ion transport
DDU33_04530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDU33_04530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDU33_04535	COG3715	PTS system
DDU33_04540	COG3716	PTS system mannose fructose sorbose family IID component
DDU33_04550	COG0531	amino acid
DDU33_04560	COG0456	acetyltransferase
DDU33_04565	COG0549	Belongs to the carbamate kinase family
DDU33_04570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDU33_04575	COG2194	sulfuric ester hydrolase activity
DDU33_04580	COG0642	Histidine kinase
DDU33_04585	COG0745	RESPONSE REGULATOR receiver
DDU33_04590	COG2259	Doxx family
DDU33_04595	COG0583	DNA-binding transcription factor activity
DDU33_04600	COG1040	competence protein
DDU33_04605	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DDU33_04610	COG5016	pyruvate
DDU33_04610	COG0511	ligase activity, forming carbon-carbon bonds
DDU33_04615	COG3630	sodium ion export across plasma membrane
DDU33_04620	COG0471	metal ion transport
DDU33_04620	COG0490	domain, Protein
DDU33_04625	COG1793	dna ligase
DDU33_04660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DDU33_04665	COG4133	protoheme IX ABC transporter activity
DDU33_04670	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DDU33_04675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DDU33_04680	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DDU33_04690	COG1138	Cytochrome C-type biogenesis protein
DDU33_04700	COG0004	ammonium transporteR
DDU33_04720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDU33_04730	COG1011	Hydrolase
DDU33_04735	COG0583	DNA-binding transcription factor activity
DDU33_04745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDU33_04785	COG2020	methyltransferase activity
DDU33_04795	COG0592	DNA-directed DNA polymerase activity
DDU33_04800	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DDU33_04830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DDU33_04840	COG0494	nUDIX hydrolase
DDU33_04860	COG1254	Belongs to the acylphosphatase family
DDU33_04865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDU33_04875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDU33_04890	COG3301	Polysulphide reductase, NrfD
DDU33_04895	COG0437	4 iron, 4 sulfur cluster binding
DDU33_04900	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DDU33_04915	COG3978	acetolactate synthase activity
DDU33_04920	COG0742	ribosomal rna small subunit methyltransferase
DDU33_04925	COG3099	Belongs to the UPF0263 family
DDU33_04935	COG4701	Protein of unknown function (DUF721)
DDU33_04945	COG1966	Carbon starvation protein
DDU33_04950	COG1322	Protein conserved in bacteria
DDU33_04955	COG0512	Glutamine amidotransferase of anthranilate synthase
DDU33_04960	COG2814	Major facilitator Superfamily
DDU33_04965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDU33_04970	COG2268	Band 7 protein
DDU33_04975	COG2841	Protein conserved in bacteria
DDU33_04985	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DDU33_04990	COG0616	signal peptide processing
DDU33_04995	COG0583	DNA-binding transcription factor activity
DDU33_05000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DDU33_05010	COG0560	Phosphoserine phosphatase
DDU33_05015	COG1666	GTP binding
DDU33_05020	COG1090	epimerase
DDU33_05025	COG1438	arginine binding
DDU33_05030	COG0039	L-malate dehydrogenase activity
DDU33_05040	COG1881	PFAM PEBP family protein
DDU33_05045	COG1126	abc transporter atp-binding protein
DDU33_05050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDU33_05055	COG4215	(ABC) transporter
DDU33_05060	COG4160	amino acid transport
DDU33_05065	COG1278	Cold shock
DDU33_05070	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
DDU33_05075	COG0793	Belongs to the peptidase S41A family
DDU33_05080	COG2989	Protein conserved in bacteria
DDU33_05085	COG3108	Peptidase M15
DDU33_05090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDU33_05100	COG2183	response to ionizing radiation
DDU33_05105	COG3063	Type IV pilus biogenesis stability protein PilW
DDU33_05115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DDU33_05120	COG0018	arginyl-trna synthetase
DDU33_05125	COG3102	Protein conserved in bacteria
DDU33_05130	COG3133	Outer membrane lipoprotein
DDU33_05140	COG0747	negative chemotaxis
DDU33_05145	COG1584	GPR1 FUN34 yaaH family protein
DDU33_05150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DDU33_05155	COG1120	ATPase activity
DDU33_05165	COG5295	Hep Hag repeat protein
DDU33_05165	COG5295	Hep Hag repeat protein
DDU33_05175	COG4232	protein-disulfide reductase activity
DDU33_05180	COG3101	peptidyl-lysine hydroxylation
DDU33_05190	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DDU33_05200	COG0745	RESPONSE REGULATOR receiver
DDU33_05205	COG2129	metallophosphoesterase
DDU33_05210	COG3172	ATPase kinase involved in NAD metabolism
DDU33_05215	COG0196	riboflavin kinase activity
DDU33_05225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDU33_05230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDU33_05235	COG1530	ribonuclease E activity
DDU33_05240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DDU33_05245	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
DDU33_05250	COG2813	Specifically methylates the guanine in position
DDU33_05255	COG1309	transcriptional regulator
DDU33_05260	COG0583	DNA-binding transcription factor activity
DDU33_05265	COG0678	peroxiredoxin activity
DDU33_05265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DDU33_05270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDU33_05275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDU33_05280	COG0024	Methionine aminopeptidase
DDU33_05285	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DDU33_05320	COG0747	negative chemotaxis
DDU33_05330	COG0747	negative chemotaxis
DDU33_05335	COG0601	transmembrane transport
DDU33_05340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDU33_05345	COG0444	Belongs to the ABC transporter superfamily
DDU33_05350	COG4608	Belongs to the ABC transporter superfamily
DDU33_05365	COG1115	amino acid carrier protein
DDU33_05370	COG0469	pyruvate kinase activity
DDU33_05375	COG2062	phosphohistidine phosphatase, SixA
DDU33_05380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDU33_05410	COG2081	HI0933 family
DDU33_05415	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DDU33_05420	COG2252	PERMEase
DDU33_05425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DDU33_05430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDU33_05445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DDU33_05450	COG1426	Protein conserved in bacteria
DDU33_05455	COG0659	secondary active sulfate transmembrane transporter activity
DDU33_05460	COG3047	cAMP biosynthetic process
DDU33_05465	COG0542	response to heat
DDU33_05485	COG1027	Aspartate ammonia-lyase
DDU33_05495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DDU33_05505	COG0720	synthase
DDU33_05510	COG0602	queuosine metabolic process
DDU33_05515	COG0316	Belongs to the HesB IscA family
DDU33_05515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DDU33_05520	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DDU33_05530	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DDU33_05535	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DDU33_05540	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DDU33_05545	COG2871	sodium ion transport
DDU33_05550	COG1477	protein flavinylation
DDU33_05555	COG2991	Protein conserved in bacteria
DDU33_05565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DDU33_05575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDU33_05585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDU33_05590	COG0512	Glutamine amidotransferase of anthranilate synthase
DDU33_05600	COG2226	methyltransferase
DDU33_05610	COG1476	TRANSCRIPTIONal
DDU33_05620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDU33_05620	COG2221	Nitrite and sulphite reductase 4Fe-4S
DDU33_05630	COG0814	amino acid
DDU33_05635	COG0814	amino acid
DDU33_05640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDU33_05645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDU33_05650	COG0346	lactoylglutathione lyase activity
DDU33_05660	COG2911	Protein conserved in bacteria
DDU33_05670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DDU33_05675	COG0617	tRNA 3'-terminal CCA addition
DDU33_05680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DDU33_05685	COG4143	(ABC) transporter
DDU33_05695	COG0402	S-adenosylhomocysteine deaminase activity
DDU33_05705	COG0424	maF-like protein
DDU33_05725	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_05760	COG1518	maintenance of DNA repeat elements
DDU33_05770	COG1605	Chorismate mutase
DDU33_05770	COG0077	Prephenate dehydratase
DDU33_05775	COG0339	signal peptide processing
DDU33_05780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DDU33_05785	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DDU33_05790	COG1882	Formate acetyltransferase
DDU33_05795	COG2116	formate transmembrane transporter activity
DDU33_05800	COG1238	metal cluster binding
DDU33_05810	COG0501	Belongs to the peptidase M48B family
DDU33_05820	COG2431	L-lysine efflux transmembrane transporter activity
DDU33_05830	COG1169	isochorismate synthase
DDU33_05835	COG0436	Aminotransferase
DDU33_05840	COG2962	Rard protein
DDU33_05850	COG1280	lysine exporter protein (LysE YggA)
DDU33_05855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDU33_05860	COG4774	siderophore transport
DDU33_05865	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_05875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDU33_05880	COG1120	ATPase activity
DDU33_05885	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DDU33_05890	COG5039	Polysaccharide pyruvyl transferase
DDU33_05900	COG3306	glycosyltransferase involved in LPS biosynthesis
DDU33_05910	COG1216	Glycosyl transferase, family 2
DDU33_05915	COG1216	Glycosyl transferase, family 2
DDU33_05925	COG2364	Membrane
DDU33_05930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DDU33_05950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DDU33_05960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDU33_05980	COG0308	aminopeptidase N
DDU33_05985	COG0477	Major facilitator Superfamily
DDU33_05990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DDU33_05995	COG0561	phosphatase activity
DDU33_06020	COG1271	oxidase subunit
DDU33_06025	COG1294	oxidase, subunit
DDU33_06045	COG0824	Thioesterase
DDU33_06050	COG0811	peptide transport
DDU33_06055	COG0848	biopolymer transport protein
DDU33_06065	COG0823	Involved in the tonB-independent uptake of proteins
DDU33_06075	COG0531	amino acid
DDU33_06095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDU33_06110	COG0628	permease
DDU33_06115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DDU33_06120	COG0795	lipopolysaccharide-transporting ATPase activity
DDU33_06125	COG0795	lipopolysaccharide-transporting ATPase activity
DDU33_06130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDU33_06140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DDU33_06145	COG0745	RESPONSE REGULATOR receiver
DDU33_06150	COG0642	Histidine kinase
DDU33_06155	COG2255	four-way junction helicase activity
DDU33_06160	COG0632	four-way junction helicase activity
DDU33_06165	COG1253	flavin adenine dinucleotide binding
DDU33_06170	COG0564	pseudouridine synthase activity
DDU33_06175	COG0406	alpha-ribazole phosphatase activity
DDU33_06180	COG1280	lysine exporter protein (LysE YggA)
DDU33_06185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DDU33_06190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DDU33_06195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDU33_06200	COG4796	Type ii and iii secretion system protein
DDU33_06220	COG4972	Pilus assembly protein
DDU33_06225	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DDU33_06230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DDU33_06235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DDU33_06240	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DDU33_06245	COG0425	Belongs to the sulfur carrier protein TusA family
DDU33_06250	COG2391	methyltransferase activity
DDU33_06255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDU33_06260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDU33_06265	COG0575	Belongs to the CDS family
DDU33_06270	COG0750	zinc metalloprotease
DDU33_06285	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DDU33_06290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDU33_06295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DDU33_06325	COG0439	Biotin carboxylase
DDU33_06330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DDU33_06335	COG4206	TonB-dependent receptor
DDU33_06345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDU33_06390	COG1410	methionine synthase
DDU33_06390	COG0646	methionine synthase
DDU33_06405	COG3066	DNA modification
DDU33_06410	COG0861	Integral membrane protein TerC family
DDU33_06425	COG0148	phosphopyruvate hydratase activity
DDU33_06430	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
DDU33_06440	COG1965	Belongs to the frataxin family
DDU33_06455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDU33_06460	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDU33_06465	COG0564	pseudouridine synthase activity
DDU33_06470	COG1862	Preprotein translocase
DDU33_06475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDU33_06480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDU33_06485	COG1528	Iron-storage protein
DDU33_06490	COG1528	Iron-storage protein
DDU33_06495	COG2252	PERMEase
DDU33_06500	COG1408	metallophosphoesterase
DDU33_06505	COG0753	catalase activity
DDU33_06510	COG0626	cystathionine gamma-synthase activity
DDU33_06515	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DDU33_06570	COG0110	maltose O-acetyltransferase activity
DDU33_06575	COG1733	regulation of RNA biosynthetic process
DDU33_06585	COG1902	pentaerythritol trinitrate reductase activity
DDU33_06605	COG0110	maltose O-acetyltransferase activity
DDU33_06610	COG1733	regulation of RNA biosynthetic process
DDU33_06630	COG0583	DNA-binding transcription factor activity
DDU33_06635	COG0859	PFAM glycosyl transferase family 9
DDU33_06645	COG0254	rRNA binding
DDU33_06655	COG0733	neurotransmitter:sodium symporter activity
DDU33_06675	COG1660	Displays ATPase and GTPase activities
DDU33_06680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDU33_06685	COG1137	ATPase activity
DDU33_06690	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DDU33_06695	COG3117	lipopolysaccharide transmembrane transporter activity
DDU33_06700	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DDU33_06705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DDU33_06715	COG1704	LemA family
DDU33_06720	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDU33_06725	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DDU33_06730	COG0194	GDP metabolic process
DDU33_06735	COG1538	Outer membrane efflux protein
DDU33_06740	COG2914	Belongs to the UPF0125 (RnfH) family
DDU33_06745	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DDU33_06750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DDU33_06765	COG1454	alcohol dehydrogenase
DDU33_06765	COG1012	belongs to the aldehyde dehydrogenase family
DDU33_06775	COG0105	UTP biosynthetic process
DDU33_06780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDU33_06780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDU33_06785	COG1105	Belongs to the carbohydrate kinase PfkB family
DDU33_06790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDU33_06790	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DDU33_06790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDU33_06795	COG1534	Rna-binding protein
DDU33_06800	COG0671	phosphoesterase, PA-phosphatase related
DDU33_06805	COG1940	carbohydrate kinase activity
DDU33_06810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDU33_06815	COG0181	hydroxymethylbilane synthase activity
DDU33_06825	COG2959	enzyme of heme biosynthesis
DDU33_06830	COG3071	HemY protein
DDU33_06840	COG3023	N-Acetylmuramoyl-L-alanine amidase
DDU33_06845	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DDU33_06850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DDU33_06855	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_06860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DDU33_06865	COG4149	molybdate abc transporter
DDU33_06870	COG0725	ABC transporter, periplasmic molybdate-binding protein
DDU33_06875	COG0842	Transport permease protein
DDU33_06880	COG1131	(ABC) transporter
DDU33_06885	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDU33_06890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDU33_06895	COG2920	part of a sulfur-relay system
DDU33_06900	COG0670	Belongs to the BI1 family
DDU33_06905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDU33_06915	COG1441	menaquinone biosynthetic process
DDU33_06920	COG1187	pseudouridine synthase activity
DDU33_06925	COG2814	Major facilitator Superfamily
DDU33_06930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDU33_06940	COG3118	belongs to the thioredoxin family
DDU33_06950	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DDU33_06965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DDU33_06970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DDU33_06975	COG0534	Mate efflux family protein
DDU33_06980	COG1074	ATP-dependent DNA helicase activity
DDU33_07000	COG0673	inositol 2-dehydrogenase activity
DDU33_07005	COG1764	response to oxidative stress
DDU33_07010	COG2207	Transcriptional regulator
DDU33_07015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DDU33_07035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DDU33_07065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDU33_07070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDU33_07075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDU33_07085	COG4942	peptidase
DDU33_07090	COG2861	carbohydrate metabolic process
DDU33_07095	COG0729	surface antigen
DDU33_07100	COG2911	Protein conserved in bacteria
DDU33_07105	COG4988	ABC transporter
DDU33_07110	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DDU33_07115	COG0318	PFAM AMP-dependent synthetase and ligase
DDU33_07125	COG3026	antisigma factor binding
DDU33_07130	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
DDU33_07135	COG1595	DNA-templated transcription, initiation
DDU33_07140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDU33_07150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DDU33_07155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDU33_07170	COG1556	Lactate utilization protein
DDU33_07175	COG1139	Iron-sulfur cluster binding protein
DDU33_07180	COG0247	lactate metabolic process
DDU33_07185	COG1620	l-lactate permease
DDU33_07195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDU33_07200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DDU33_07205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DDU33_07215	COG0737	Belongs to the 5'-nucleotidase family
DDU33_07220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DDU33_07225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DDU33_07230	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DDU33_07230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDU33_07260	COG0561	phosphatase activity
DDU33_07270	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDU33_07275	COG0567	Dehydrogenase, E1 component
DDU33_07280	COG2831	hemolysin activation secretion protein
DDU33_07285	COG3210	domain, Protein
DDU33_07285	COG3210	domain, Protein
DDU33_07310	COG1121	(ABC) transporter
DDU33_07315	COG0739	heme binding
DDU33_07320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDU33_07325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DDU33_07335	COG0561	phosphatase activity
DDU33_07340	COG3850	Histidine kinase
DDU33_07350	COG4608	Belongs to the ABC transporter superfamily
DDU33_07370	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DDU33_07380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDU33_07390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DDU33_07395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DDU33_07400	COG0590	tRNA wobble adenosine to inosine editing
DDU33_07405	COG0513	Belongs to the DEAD box helicase family
DDU33_07410	COG4785	May be involved in cell division
DDU33_07420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDU33_07430	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DDU33_07445	COG3105	Protein conserved in bacteria
DDU33_07450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDU33_07470	COG0481	GTPase activity
DDU33_07475	COG0681	Belongs to the peptidase S26 family
DDU33_07485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDU33_07500	COG2814	Major facilitator Superfamily
DDU33_07505	COG3083	sulfuric ester hydrolase activity
DDU33_07520	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_07530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDU33_07535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DDU33_07540	COG0295	cytidine deaminase activity
DDU33_07545	COG0425	Belongs to the sulfur carrier protein TusA family
DDU33_07550	COG2391	methyltransferase activity
DDU33_07560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DDU33_07570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDU33_07580	COG0539	negative regulation of cytoplasmic translation
DDU33_07585	COG0776	regulation of translation
DDU33_07590	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DDU33_07595	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DDU33_07600	COG0284	orotidine-5'-phosphate decarboxylase activity
DDU33_07605	COG0023	Translation Initiation Factor
DDU33_07610	COG0527	aspartate kinase activity
DDU33_07705	COG0582	viral genome integration into host DNA
DDU33_07715	COG0248	Ppx GppA phosphatase
DDU33_07720	COG2731	YhcH YjgK YiaL family protein
DDU33_07725	COG1737	Transcriptional regulator
DDU33_07730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DDU33_07745	COG0613	PHP domain protein
DDU33_07755	COG4974	Belongs to the 'phage' integrase family
DDU33_07845	COG4695	Portal protein
DDU33_07965	COG0314	molybdopterin synthase activity
DDU33_07970	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DDU33_07985	COG2363	Small membrane protein
DDU33_08000	COG1846	Transcriptional regulator
DDU33_08005	COG2207	Transcriptional regulator
DDU33_08005	COG1917	Cupin 2, conserved barrel domain protein
DDU33_08030	COG4381	Mu-like prophage protein gp46
DDU33_08110	COG5002	protein histidine kinase activity
DDU33_08115	COG0745	RESPONSE REGULATOR receiver
DDU33_08150	COG0556	nucleotide-excision repair
DDU33_08160	COG3842	ATPase activity
DDU33_08170	COG1840	ABC-type Fe3 transport system, periplasmic component
DDU33_08185	COG2925	Exonuclease
DDU33_08190	COG3094	Invasion gene expression up-regulator, SirB
DDU33_08195	COG3028	Belongs to the UPF0307 family
DDU33_08200	COG0312	modulator of DNA gyrase
DDU33_08205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DDU33_08215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDU33_08220	COG0625	glutathione transferase activity
DDU33_08225	COG2969	positive regulation of protein catabolic process
DDU33_08235	COG0626	cystathionine gamma-synthase activity
DDU33_08245	COG1121	(ABC) transporter
DDU33_08250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDU33_08255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDU33_08260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDU33_08270	COG0779	Required for maturation of 30S ribosomal subunits
DDU33_08275	COG0195	Participates in both transcription termination and antitermination
DDU33_08280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DDU33_08290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDU33_08300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DDU33_08305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDU33_08310	COG2951	lytic endotransglycosylase activity
DDU33_08315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DDU33_08320	COG1523	belongs to the glycosyl hydrolase 13 family
DDU33_08335	COG0058	SHG alpha-glucan phosphorylase activity
DDU33_08340	COG0277	FAD linked oxidase domain protein
DDU33_08345	COG0857	belongs to the CobB CobQ family
DDU33_08345	COG0280	phosphate acetyltransferase
DDU33_08370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDU33_08370	COG0475	glutathione-regulated potassium exporter activity
DDU33_08375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DDU33_08380	COG1444	tRNA N-acetyltransferase activity
DDU33_08385	COG1448	Aminotransferase
DDU33_08410	COG0285	dihydrofolate synthase activity
DDU33_08415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DDU33_08420	COG3956	TIGRFAM MazG family protein
DDU33_08425	COG0745	RESPONSE REGULATOR receiver
DDU33_08430	COG2205	protein histidine kinase activity
DDU33_08435	COG1136	(ABC) transporter
DDU33_08435	COG0577	efflux transmembrane transporter activity
DDU33_08440	COG1494	fructose-1,6-bisphosphatase
DDU33_08445	COG3074	FtsZ-dependent cytokinesis
DDU33_08455	COG1214	PFAM Peptidase M22, glycoprotease
DDU33_08460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DDU33_08465	COG2321	neutral zinc metallopeptidase
DDU33_08470	COG1674	ftsk spoiiie
DDU33_08475	COG1522	sequence-specific DNA binding
DDU33_08480	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DDU33_08485	COG1846	Transcriptional regulator
DDU33_08485	COG1940	carbohydrate kinase activity
DDU33_08490	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DDU33_08495	COG0433	COG0433 Predicted ATPase
DDU33_08510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDU33_08515	COG0583	DNA-binding transcription factor activity
DDU33_08525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DDU33_08535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DDU33_08540	COG0791	NLP P60 protein
DDU33_08545	COG0776	regulation of translation
DDU33_08550	COG0072	phenylalanine-tRNA ligase activity
DDU33_08555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DDU33_08565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDU33_08570	COG3100	YcgL domain-containing protein
DDU33_08575	COG0305	Participates in initiation and elongation during chromosome replication
DDU33_08580	COG1509	lysine 2,3-aminomutase activity
DDU33_08590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDU33_08595	COG4607	ABC-type enterochelin transport system periplasmic component
DDU33_08600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDU33_08605	COG4605	iron ion homeostasis
DDU33_08610	COG4604	ABC transporter, ATP-binding protein
DDU33_08615	COG1392	Phosphate transport regulator
DDU33_08620	COG0306	phosphate transporter
DDU33_08625	COG4991	sh3 domain protein
DDU33_08635	COG0741	lytic transglycosylase activity
DDU33_08640	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DDU33_08645	COG0006	proline dipeptidase activity
DDU33_08660	COG4680	protein conserved in bacteria
DDU33_08675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDU33_08680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDU33_08685	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
DDU33_08690	COG1823	symporter activity
DDU33_08695	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
DDU33_08700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDU33_08705	COG0233	cytoplasmic translational termination
DDU33_08710	COG0528	UMP kinase activity
DDU33_08715	COG2194	sulfuric ester hydrolase activity
DDU33_08725	COG3264	Mechanosensitive ion channel
DDU33_08725	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DDU33_08730	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DDU33_08730	COG3264	Mechanosensitive ion channel
DDU33_08735	COG0318	PFAM AMP-dependent synthetase and ligase
DDU33_08740	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
DDU33_08745	COG0596	Alpha beta hydrolase
DDU33_08750	COG2226	methyltransferase
DDU33_08765	COG4178	(ABC) transporter
DDU33_08770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDU33_08775	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DDU33_08780	COG0517	IMP dehydrogenase activity
DDU33_08780	COG0516	GMP reductase activity
DDU33_08810	COG3955	Domain of unknown function (DUF1919)
DDU33_08815	COG1115	amino acid carrier protein
DDU33_08820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDU33_08825	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDU33_08830	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DDU33_08840	COG0167	dihydroorotate dehydrogenase activity
DDU33_08845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDU33_08850	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DDU33_08860	COG0121	glutamine amidotransferase
DDU33_08865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDU33_08870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DDU33_08875	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DDU33_08880	COG1792	Involved in formation and maintenance of cell shape
DDU33_08885	COG1077	Cell shape determining protein MreB Mrl
DDU33_08890	COG1279	arginine transmembrane transporter activity
DDU33_08895	COG0572	uridine kinase
DDU33_08900	COG0717	Belongs to the dCTP deaminase family
DDU33_08905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDU33_08910	COG0483	inositol monophosphate 1-phosphatase activity
DDU33_08925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DDU33_08930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DDU33_08945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDU33_08945	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DDU33_08945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDU33_08950	COG1461	Dihydroxyacetone kinase
DDU33_08955	COG2376	Dihydroxyacetone kinase
DDU33_08960	COG1368	sulfuric ester hydrolase activity
DDU33_08965	COG1722	exodeoxyribonuclease VII activity
DDU33_08970	COG0142	geranyltranstransferase activity
DDU33_08975	COG1560	Kdo2-lipid A biosynthetic process
DDU33_08980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DDU33_08990	COG0302	gtp cyclohydrolase
DDU33_08995	COG3642	lipopolysaccharide core region biosynthetic process
DDU33_09000	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DDU33_09015	COG0425	Belongs to the sulfur carrier protein TusA family
DDU33_09020	COG3945	hemerythrin HHE cation binding domain
DDU33_09025	COG0343	queuine tRNA-ribosyltransferase activity
DDU33_09035	COG0288	reversible hydration of carbon dioxide
DDU33_09040	COG0028	Belongs to the TPP enzyme family
DDU33_09045	COG0440	acetolactate synthase activity
DDU33_09050	COG3036	rescue of stalled ribosome
DDU33_09055	COG2226	methyltransferase
DDU33_09070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DDU33_09080	COG2333	competence protein COMEC
DDU33_09080	COG0658	competence protein
DDU33_09085	COG0135	phosphoribosylanthranilate isomerase activity
DDU33_09085	COG0134	indole-3-glycerol-phosphate synthase activity
DDU33_09090	COG3098	single-species biofilm formation
DDU33_09095	COG0564	pseudouridine synthase activity
DDU33_09100	COG3140	Belongs to the UPF0181 family
DDU33_09110	COG3025	triphosphatase activity
DDU33_09115	COG3106	COG3106 Predicted ATPase
DDU33_09120	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DDU33_09130	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DDU33_09135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DDU33_09140	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DDU33_09145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDU33_09150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDU33_09165	COG0589	response to stress
DDU33_09175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DDU33_09185	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_09195	COG0471	metal ion transport
DDU33_09200	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DDU33_09200	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DDU33_09205	COG3051	citrate lyase alpha subunit
DDU33_09210	COG2301	Belongs to the HpcH HpaI aldolase family
DDU33_09215	COG3052	prosthetic group binding
DDU33_09220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DDU33_09235	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DDU33_09240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DDU33_09240	COG0237	dephospho-CoA kinase activity
DDU33_09250	COG1459	type II secretion system
DDU33_09255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDU33_09265	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DDU33_09270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DDU33_09275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DDU33_09280	COG0730	response to heat
DDU33_09285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DDU33_09300	COG3077	Addiction module antitoxin, RelB DinJ family
DDU33_09335	COG2378	regulation of single-species biofilm formation
DDU33_09345	COG0215	cysteine-tRNA ligase activity
DDU33_09350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DDU33_09355	COG0617	tRNA 3'-terminal CCA addition
DDU33_09360	COG1396	sequence-specific DNA binding
DDU33_09375	COG0737	Belongs to the 5'-nucleotidase family
DDU33_09380	COG2975	iron-sulfur cluster assembly
DDU33_09385	COG0633	Ferredoxin
DDU33_09405	COG1216	Glycosyl transferase, family 2
DDU33_09405	COG1442	glycosyl transferase family 8
DDU33_09410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DDU33_09420	COG0822	iron-sulfur transferase activity
DDU33_09425	COG1104	cysteine desulfurase activity
DDU33_09430	COG1959	2 iron, 2 sulfur cluster binding
DDU33_09440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDU33_09445	COG0784	Response regulator, receiver
DDU33_09445	COG2198	Histidine kinase
DDU33_09445	COG5002	protein histidine kinase activity
DDU33_09450	COG0697	spore germination
DDU33_09455	COG2840	Smr protein MutS2
DDU33_09465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDU33_09470	COG2027	D-alanyl-D-alanine carboxypeptidase
DDU33_09480	COG1160	GTP binding
DDU33_09485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DDU33_09485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DDU33_09490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDU33_09495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDU33_09500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DDU33_09510	COG1346	cytolysis
DDU33_09515	COG1380	Effector of murein hydrolase LrgA
DDU33_09520	COG1199	ATP-dependent helicase activity
DDU33_09535	COG2005	Transcriptional regulator
DDU33_09540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDU33_09545	COG0629	single-stranded DNA binding
DDU33_09555	COG4172	Belongs to the ABC transporter superfamily
DDU33_09560	COG4171	peptide transport system, permease
DDU33_09565	COG4168	peptide transport system, permease
DDU33_09570	COG4166	transmembrane transport
DDU33_09575	COG3283	Transcriptional regulator of aromatic amino acids metabolism
DDU33_09580	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DDU33_09590	COG0814	amino acid
DDU33_09595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDU33_09610	COG1879	ABC-type sugar transport system periplasmic component
DDU33_09615	COG1757	Na H antiporter
DDU33_09625	COG0788	formyltetrahydrofolate deformylase activity
DDU33_09630	COG2949	membrane
DDU33_09635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDU33_09645	COG0586	Pfam SNARE associated Golgi protein
DDU33_09665	COG0495	leucyl-tRNA aminoacylation
DDU33_09670	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DDU33_09675	COG1466	dna polymerase III delta subunit
DDU33_09680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DDU33_09685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDU33_09700	COG0786	glutamate:sodium symporter activity
DDU33_09715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DDU33_09720	COG2354	Protein conserved in bacteria
DDU33_09725	COG2826	transposase and inactivated derivatives, IS30 family
DDU33_09735	COG4535	Mg2 and Co2 transporter CorC
DDU33_09740	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DDU33_09745	COG0783	Belongs to the Dps family
DDU33_09750	COG0189	ligase activity
DDU33_09760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDU33_09775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDU33_09775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDU33_09780	COG1476	TRANSCRIPTIONal
DDU33_09795	COG0159	tryptophan synthase activity
DDU33_09800	COG0133	tryptophan synthase activity
DDU33_09805	COG4221	oxidoreductase activity
DDU33_09810	COG2983	Belongs to the UPF0260 family
DDU33_09815	COG0393	Putative heavy-metal-binding
DDU33_09820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DDU33_09830	COG5645	(Lipo)protein
DDU33_09835	COG0183	Belongs to the thiolase family
DDU33_09840	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDU33_09840	COG1024	Enoyl-CoA hydratase
DDU33_09850	COG1760	l-serine dehydratase
DDU33_09860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DDU33_09865	COG0243	molybdopterin cofactor binding
DDU33_09865	COG3383	formate dehydrogenase (NAD+) activity
DDU33_09870	COG0243	molybdopterin cofactor binding
DDU33_09870	COG3383	formate dehydrogenase (NAD+) activity
DDU33_09875	COG0437	4 iron, 4 sulfur cluster binding
DDU33_09880	COG2864	formate dehydrogenase
DDU33_09885	COG3058	Necessary for formate dehydrogenase activity
DDU33_09895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDU33_09905	COG0385	Bile acid
DDU33_09910	COG0045	succinate-CoA ligase (ADP-forming) activity
DDU33_09915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DDU33_09920	COG0187	DNA topoisomerase II activity
DDU33_09925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDU33_09930	COG0366	Alpha amylase catalytic
DDU33_09935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDU33_09935	COG1263	PTS System
DDU33_09945	COG2915	High frequency lysogenization protein hflD homolog
DDU33_09950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DDU33_09970	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DDU33_09980	COG0500	methyltransferase
DDU33_09985	COG1944	ATP diphosphatase activity
DDU33_09990	COG1530	ribonuclease E activity
DDU33_09995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDU33_10005	COG2095	MarC family integral membrane protein
DDU33_10015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DDU33_10020	COG1678	Uncharacterized ACR, COG1678
DDU33_10025	COG0564	pseudouridine synthase activity
DDU33_10040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDU33_10045	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DDU33_10050	COG3593	DNA synthesis involved in DNA repair
DDU33_10055	COG1611	Belongs to the LOG family
DDU33_10070	COG2017	converts alpha-aldose to the beta-anomer
DDU33_10080	COG1085	galactose-1-phosphate uridylyltransferase
DDU33_10105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DDU33_10110	COG0303	'Molybdopterin
DDU33_10120	COG1286	toxin biosynthetic process
DDU33_10125	COG0328	RNA-DNA hybrid ribonuclease activity
DDU33_10135	COG0859	PFAM glycosyl transferase family 9
DDU33_10140	COG1686	Belongs to the peptidase S11 family
DDU33_10145	COG0463	Glycosyl transferase, family 2
DDU33_10150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DDU33_10160	COG2707	UPF0756 membrane protein
DDU33_10165	COG1643	Atp-dependent helicase
DDU33_10180	COG1132	(ABC) transporter
DDU33_10185	COG4988	ABC transporter
DDU33_10190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDU33_10195	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
DDU33_10200	COG2932	Transcriptional regulator
DDU33_10205	COG0791	NLP P60 protein
DDU33_10215	COG3381	protein complex oligomerization
DDU33_10245	COG0489	protein tyrosine kinase activity
DDU33_10250	COG4166	transmembrane transport
DDU33_10255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDU33_10270	COG0138	bifunctional purine biosynthesis protein purh
DDU33_10280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDU33_10300	COG1132	(ABC) transporter
DDU33_10305	COG2350	Protein conserved in bacteria
DDU33_10310	COG1607	acyl-coa hydrolase
DDU33_10325	COG3092	negative regulation of chromosome organization
DDU33_10330	COG0037	tRNA processing
DDU33_10335	COG2056	Na+-H+ antiporter family
DDU33_10340	COG0708	Exodeoxyribonuclease III
DDU33_10350	COG0301	tRNA thio-modification
DDU33_10350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDU33_10360	COG0330	HflC and HflK could
DDU33_10365	COG0330	HflC and HflK could
DDU33_10390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDU33_10395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DDU33_10430	COG0527	aspartate kinase activity
DDU33_10430	COG0460	homoserine dehydrogenase
DDU33_10435	COG0083	homoserine kinase activity
DDU33_10440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDU33_10445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DDU33_10455	COG0471	metal ion transport
DDU33_10465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDU33_10470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDU33_10480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DDU33_10495	COG3068	Protein conserved in bacteria
DDU33_10510	COG3115	cell septum assembly
DDU33_10535	COG4657	Part of a membrane complex involved in electron transport
DDU33_10540	COG2878	Part of a membrane complex involved in electron transport
DDU33_10545	COG4656	Part of a membrane complex involved in electron transport
DDU33_10560	COG0110	maltose O-acetyltransferase activity
DDU33_10570	COG1253	flavin adenine dinucleotide binding
DDU33_10575	COG1560	Kdo2-lipid A biosynthetic process
DDU33_10580	COG3008	intermembrane lipid transfer
DDU33_10585	COG1854	S-ribosylhomocysteine lyase activity
DDU33_10590	COG1132	(ABC) transporter
DDU33_10610	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
DDU33_10615	COG3306	glycosyltransferase involved in LPS biosynthesis
DDU33_10625	COG3030	protein affecting phage T7 exclusion by the F plasmid
DDU33_10635	COG1187	pseudouridine synthase activity
DDU33_10650	COG0716	FMN binding
DDU33_10655	COG0735	belongs to the Fur family
DDU33_10665	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DDU33_10675	COG2177	Part of the ABC transporter FtsEX involved in
DDU33_10680	COG2884	Cell division ATP-binding protein ftsE
DDU33_10685	COG0552	protein localization to endoplasmic reticulum
DDU33_10700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDU33_10715	COG1138	Cytochrome C-type biogenesis protein
DDU33_10720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDU33_10725	COG3088	subunit of a heme lyase
DDU33_10725	COG4235	cytochrome complex assembly
DDU33_10730	COG4235	cytochrome complex assembly
DDU33_10735	COG0494	nUDIX hydrolase
DDU33_10755	COG0789	Transcriptional regulator
DDU33_10765	COG2217	Heavy metal translocating P-type atpase
DDU33_10770	COG0300	oxidoreductase activity
DDU33_10775	COG0778	Nitroreductase
DDU33_10785	COG0166	Belongs to the GPI family
DDU33_10815	COG0488	(ABC) transporter
DDU33_10825	COG0271	Belongs to the BolA IbaG family
DDU33_10830	COG1177	transmembrane transport
DDU33_10835	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDU33_10840	COG3842	ATPase activity