locus-tag	class	description
Asuc_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Asuc_0002	COG0592	DNA-directed DNA polymerase activity
Asuc_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Asuc_0005	COG0277	FAD linked oxidase domain protein
Asuc_0006	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Asuc_0006	COG0475	glutathione-regulated potassium exporter activity
Asuc_0007	COG2226	methyltransferase
Asuc_0010	COG1309	transcriptional regulator
Asuc_0011	COG0756	dUTP diphosphatase activity
Asuc_0012	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Asuc_0013	COG2003	Belongs to the UPF0758 family
Asuc_0014	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Asuc_0015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Asuc_0016	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asuc_0017	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asuc_0018	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Asuc_0019	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Asuc_0020	COG0471	metal ion transport
Asuc_0021	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asuc_0021	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asuc_0022	COG4178	(ABC) transporter
Asuc_0023	COG2985	domain, Protein
Asuc_0024	COG0513	Belongs to the DEAD box helicase family
Asuc_0027	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Asuc_0028	COG2915	High frequency lysogenization protein hflD homolog
Asuc_0030	COG0582	viral genome integration into host DNA
Asuc_0032	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Asuc_0034	COG1464	Belongs to the NlpA lipoprotein family
Asuc_0038	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Asuc_0039	COG0513	Belongs to the DEAD box helicase family
Asuc_0040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Asuc_0041	COG0085	RNA polymerase activity
Asuc_0042	COG0222	ribosome binding
Asuc_0043	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Asuc_0044	COG0081	regulation of translation
Asuc_0045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Asuc_0048	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Asuc_0049	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Asuc_0051	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Asuc_0052	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Asuc_0053	COG0589	response to stress
Asuc_0054	COG3956	TIGRFAM MazG family protein
Asuc_0057	COG1132	(ABC) transporter
Asuc_0058	COG0438	transferase activity, transferring glycosyl groups
Asuc_0062	COG0656	L-ascorbic acid biosynthetic process
Asuc_0064	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Asuc_0066	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Asuc_0071	COG0110	maltose O-acetyltransferase activity
Asuc_0073	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Asuc_0074	COG1275	C4-dicarboxylate transporter malic acid transport protein
Asuc_0079	COG2814	Major facilitator Superfamily
Asuc_0081	COG1879	ABC-type sugar transport system periplasmic component
Asuc_0082	COG1129	ABC transporter
Asuc_0083	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asuc_0085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Asuc_0085	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Asuc_0085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Asuc_0086	COG1105	Belongs to the carbohydrate kinase PfkB family
Asuc_0087	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0087	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0089	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asuc_0091	COG0705	Rhomboid family
Asuc_0092	COG1349	DNA-binding transcription factor activity
Asuc_0094	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Asuc_0095	COG1072	(Pantothenic acid kinase))
Asuc_0097	COG1596	polysaccharide export
Asuc_0099	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asuc_0102	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asuc_0106	COG0438	transferase activity, transferring glycosyl groups
Asuc_0111	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Asuc_0112	COG0242	peptide deformylase activity
Asuc_0113	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asuc_0115	COG1297	OPT oligopeptide transporter protein
Asuc_0117	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Asuc_0119	COG2610	gluconate transmembrane transporter activity
Asuc_0120	COG3622	Belongs to the hyi family
Asuc_0121	COG0235	Class ii aldolase
Asuc_0122	COG3395	kinase activity
Asuc_0123	COG2084	Dehydrogenase
Asuc_0124	COG1349	DNA-binding transcription factor activity
Asuc_0125	COG0737	Belongs to the 5'-nucleotidase family
Asuc_0126	COG1349	DNA-binding transcription factor activity
Asuc_0129	COG1070	Carbohydrate kinase
Asuc_0132	COG0187	DNA topoisomerase II activity
Asuc_0134	COG1942	4-Oxalocrotonate Tautomerase
Asuc_0136	COG0583	DNA-binding transcription factor activity
Asuc_0137	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Asuc_0138	COG2841	Protein conserved in bacteria
Asuc_0139	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Asuc_0140	COG0252	asparaginase activity
Asuc_0141	COG1027	Aspartate ammonia-lyase
Asuc_0142	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Asuc_0143	COG3021	interspecies interaction between organisms
Asuc_0145	COG1904	glucuronate isomerase
Asuc_0147	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Asuc_0150	COG2186	Transcriptional regulator
Asuc_0151	COG1312	Catalyzes the dehydration of D-mannonate
Asuc_0152	COG0800	Aldolase
Asuc_0153	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asuc_0154	COG2721	sulfolactate sulfo-lyase activity
Asuc_0156	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Asuc_0156	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Asuc_0158	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Asuc_0159	COG1063	alcohol dehydrogenase
Asuc_0160	COG1802	Transcriptional regulator
Asuc_0162	COG3850	Histidine kinase
Asuc_0163	COG0783	Belongs to the Dps family
Asuc_0164	COG3691	Protein conserved in bacteria
Asuc_0166	COG0174	glutamine synthetase
Asuc_0169	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asuc_0170	COG3958	Transketolase
Asuc_0171	COG3959	Transketolase, thiamine diphosphate binding domain
Asuc_0172	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asuc_0175	COG1879	ABC-type sugar transport system periplasmic component
Asuc_0177	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asuc_0178	COG2195	Cleaves the N-terminal amino acid of tripeptides
Asuc_0179	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Asuc_0180	COG4149	molybdate abc transporter
Asuc_0182	COG0442	prolyl-tRNA aminoacylation
Asuc_0183	COG0471	metal ion transport
Asuc_0184	COG2828	Protein conserved in bacteria
Asuc_0186	COG2188	Transcriptional regulator
Asuc_0187	COG0625	glutathione transferase activity
Asuc_0188	COG0019	diaminopimelate decarboxylase activity
Asuc_0190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Asuc_0191	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asuc_0192	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Asuc_0193	COG1381	Involved in DNA repair and RecF pathway recombination
Asuc_0194	COG1869	D-ribose catabolic process
Asuc_0196	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asuc_0197	COG1879	ABC-type sugar transport system periplasmic component
Asuc_0198	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asuc_0200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Asuc_0202	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Asuc_0203	COG0247	lactate metabolic process
Asuc_0204	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
Asuc_0205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Asuc_0207	COG1882	Formate acetyltransferase
Asuc_0208	COG2116	formate transmembrane transporter activity
Asuc_0209	COG0537	adenosine 5'-monophosphoramidase activity
Asuc_0211	COG1472	Belongs to the glycosyl hydrolase 3 family
Asuc_0212	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Asuc_0213	COG4948	Mandelate Racemase Muconate Lactonizing
Asuc_0215	COG0583	DNA-binding transcription factor activity
Asuc_0218	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Asuc_0219	COG0546	phosphoglycolate phosphatase activity
Asuc_0221	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Asuc_0222	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Asuc_0223	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Asuc_0224	COG0494	nUDIX hydrolase
Asuc_0225	COG4221	oxidoreductase activity
Asuc_0226	COG1218	3'(2'),5'-bisphosphate nucleotidase
Asuc_0227	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Asuc_0228	COG0363	glucosamine-6-phosphate deaminase activity
Asuc_0230	COG1794	racemase activity, acting on amino acids and derivatives
Asuc_0231	COG4545	Glutaredoxin-related protein
Asuc_0232	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Asuc_0234	COG0235	Class ii aldolase
Asuc_0235	COG3623	hexulose-6-phosphate isomerase
Asuc_0240	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Asuc_0244	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
Asuc_0245	COG1970	mechanosensitive ion channel activity
Asuc_0246	COG0569	domain protein
Asuc_0247	COG0259	pyridoxamine-phosphate oxidase activity
Asuc_0249	COG1595	DNA-templated transcription, initiation
Asuc_0250	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
Asuc_0251	COG3026	antisigma factor binding
Asuc_0252	COG3086	response to oxidative stress
Asuc_0253	COG0165	Argininosuccinate lyase
Asuc_0254	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Asuc_0257	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Asuc_0258	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Asuc_0259	COG1132	(ABC) transporter
Asuc_0260	COG2137	regulation of response to DNA damage stimulus
Asuc_0261	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Asuc_0262	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Asuc_0263	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Asuc_0264	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Asuc_0267	COG1414	Transcriptional regulator
Asuc_0268	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Asuc_0269	COG2731	YhcH YjgK YiaL family protein
Asuc_0270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Asuc_0271	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Asuc_0272	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Asuc_0273	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Asuc_0275	COG0385	Bile acid
Asuc_0276	COG0668	transmembrane transport
Asuc_0277	COG2267	carboxylic ester hydrolase activity
Asuc_0278	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Asuc_0279	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Asuc_0280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Asuc_0281	COG0049	tRNA binding
Asuc_0284	COG0733	neurotransmitter:sodium symporter activity
Asuc_0286	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Asuc_0286	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0287	COG3715	PTS system
Asuc_0288	COG3716	PTS system mannose fructose sorbose family IID component
Asuc_0290	COG1763	Mo-molybdopterin cofactor biosynthetic process
Asuc_0291	COG2814	Major facilitator Superfamily
Asuc_0292	COG1285	pathogenesis
Asuc_0293	COG1040	competence protein
Asuc_0295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Asuc_0296	COG0316	Belongs to the HesB IscA family
Asuc_0296	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Asuc_0297	COG2818	Glycosylase
Asuc_0298	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asuc_0299	COG0765	amino acid transport
Asuc_0300	COG1126	abc transporter atp-binding protein
Asuc_0303	COG3630	sodium ion export across plasma membrane
Asuc_0304	COG0471	metal ion transport
Asuc_0305	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
Asuc_0307	COG3085	chromosome segregation
Asuc_0308	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asuc_0309	COG3084	Protein conserved in bacteria
Asuc_0310	COG0746	molybdenum cofactor guanylyltransferase activity
Asuc_0311	COG4989	oxidoreductase activity
Asuc_0312	COG1640	4-alpha-glucanotransferase
Asuc_0313	COG0058	SHG alpha-glucan phosphorylase activity
Asuc_0314	COG2909	trisaccharide binding
Asuc_0315	COG0366	Alpha amylase catalytic
Asuc_0316	COG3833	ABC-type maltose transport systems, permease component
Asuc_0317	COG1175	transmembrane transport
Asuc_0318	COG2182	Extracellular solute-binding protein
Asuc_0319	COG2182	Extracellular solute-binding protein
Asuc_0320	COG3842	ATPase activity
Asuc_0322	COG4580	involved in the transport of maltose and maltodextrins
Asuc_0324	COG0561	phosphatase activity
Asuc_0325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Asuc_0326	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Asuc_0327	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Asuc_0328	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Asuc_0329	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Asuc_0330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Asuc_0332	COG0356	it plays a direct role in the translocation of protons across the membrane
Asuc_0333	COG3312	ion transport
Asuc_0334	COG0357	Ribosomal RNA small subunit methyltransferase G
Asuc_0335	COG0445	tRNA wobble uridine modification
Asuc_0336	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Asuc_0337	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Asuc_0338	COG0009	L-threonylcarbamoyladenylate synthase
Asuc_0339	COG0551	DNA topoisomerase type I activity
Asuc_0340	COG1322	Protein conserved in bacteria
Asuc_0341	COG1490	D-aminoacyl-tRNA deacylase activity
Asuc_0342	COG1295	ribonuclease BN
Asuc_0343	COG3012	SEC-C Motif Domain Protein
Asuc_0344	COG0433	COG0433 Predicted ATPase
Asuc_0345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Asuc_0346	COG1965	Belongs to the frataxin family
Asuc_0347	COG0514	ATP-dependent DNA helicase (RecQ)
Asuc_0349	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Asuc_0350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Asuc_0351	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asuc_0352	COG1151	hydroxylamine reductase activity
Asuc_0353	COG3071	HemY protein
Asuc_0354	COG2959	enzyme of heme biosynthesis
Asuc_0356	COG0181	hydroxymethylbilane synthase activity
Asuc_0358	COG2211	Major facilitator Superfamily
Asuc_0360	COG0673	inositol 2-dehydrogenase activity
Asuc_0362	COG2197	response regulator
Asuc_0363	COG0729	surface antigen
Asuc_0364	COG2911	Protein conserved in bacteria
Asuc_0365	COG0248	Ppx GppA phosphatase
Asuc_0366	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Asuc_0367	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Asuc_0368	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Asuc_0369	COG1063	alcohol dehydrogenase
Asuc_0370	COG1312	Catalyzes the dehydration of D-mannonate
Asuc_0371	COG0246	Mannitol dehydrogenase
Asuc_0372	COG1802	Transcriptional regulator
Asuc_0373	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asuc_0374	COG0800	Aldolase
Asuc_0375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Asuc_0379	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Asuc_0380	COG3078	GTPase activator activity
Asuc_0382	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Asuc_0383	COG0515	serine threonine protein kinase
Asuc_0384	COG1045	serine acetyltransferase
Asuc_0386	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Asuc_0387	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asuc_0388	COG2177	Part of the ABC transporter FtsEX involved in
Asuc_0389	COG2884	Cell division ATP-binding protein ftsE
Asuc_0390	COG0678	peroxiredoxin activity
Asuc_0390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Asuc_0391	COG0583	DNA-binding transcription factor activity
Asuc_0392	COG1309	transcriptional regulator
Asuc_0393	COG3074	FtsZ-dependent cytokinesis
Asuc_0394	COG1494	fructose-1,6-bisphosphatase
Asuc_0401	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asuc_0403	COG1454	alcohol dehydrogenase
Asuc_0404	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asuc_0405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asuc_0406	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
Asuc_0407	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
Asuc_0408	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Asuc_0409	COG0752	glycyl-tRNA synthetase alpha subunit
Asuc_0410	COG0751	glycine-tRNA ligase activity
Asuc_0411	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Asuc_0412	COG0561	phosphatase activity
Asuc_0414	COG3978	acetolactate synthase activity
Asuc_0415	COG0129	dihydroxy-acid dehydratase activity
Asuc_0418	COG0354	folic acid binding
Asuc_0419	COG1561	YicC-like family, N-terminal region
Asuc_0420	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Asuc_0421	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Asuc_0422	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Asuc_0422	COG0047	phosphoribosylformylglycinamidine synthase activity
Asuc_0425	COG0295	cytidine deaminase activity
Asuc_0427	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Asuc_0428	COG0251	oxidation-reduction process
Asuc_0429	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Asuc_0430	COG0742	ribosomal rna small subunit methyltransferase
Asuc_0431	COG1187	pseudouridine synthase activity
Asuc_0432	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Asuc_0434	COG3730	PTS system glucitol sorbitol-specific
Asuc_0437	COG1028	Short-chain dehydrogenase reductase Sdr
Asuc_0439	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0440	COG1349	DNA-binding transcription factor activity
Asuc_0441	COG1921	L-seryl-tRNASec selenium transferase activity
Asuc_0442	COG3276	selenocysteine insertion sequence binding
Asuc_0443	COG3477	response to acidic pH
Asuc_0444	COG0742	ribosomal rna small subunit methyltransferase
Asuc_0445	COG0552	protein localization to endoplasmic reticulum
Asuc_0446	COG3395	kinase activity
Asuc_0449	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Asuc_0451	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Asuc_0452	COG0786	glutamate:sodium symporter activity
Asuc_0454	COG0038	chloride channel
Asuc_0456	COG0246	Mannitol dehydrogenase
Asuc_0457	COG3722	fumarate hydratase activity
Asuc_0458	COG0051	transcription antitermination factor activity, RNA binding
Asuc_0459	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Asuc_0460	COG0088	Forms part of the polypeptide exit tunnel
Asuc_0461	COG0089	rRNA binding
Asuc_0462	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Asuc_0463	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Asuc_0464	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Asuc_0465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Asuc_0466	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Asuc_0467	COG0255	Belongs to the universal ribosomal protein uL29 family
Asuc_0468	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Asuc_0469	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Asuc_0470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Asuc_0471	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Asuc_0472	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Asuc_0473	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Asuc_0474	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Asuc_0475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Asuc_0476	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Asuc_0477	COG1841	ribosomal large subunit assembly
Asuc_0478	COG0200	Binds to the 23S rRNA
Asuc_0479	COG0201	protein transport
Asuc_0480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Asuc_0481	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Asuc_0482	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Asuc_0483	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Asuc_0484	COG0202	RNA polymerase activity
Asuc_0485	COG0203	ribosomal protein L17
Asuc_0486	COG2129	metallophosphoesterase
Asuc_0487	COG3172	ATPase kinase involved in NAD metabolism
Asuc_0488	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asuc_0490	COG1129	ABC transporter
Asuc_0491	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asuc_0494	COG2160	L-arabinose isomerase activity
Asuc_0495	COG2207	Transcriptional regulator
Asuc_0495	COG1609	Transcriptional regulator
Asuc_0496	COG0477	Major facilitator Superfamily
Asuc_0496	COG2814	Major facilitator Superfamily
Asuc_0497	COG4214	carbohydrate transport
Asuc_0498	COG1129	ABC transporter
Asuc_0499	COG4213	ABC transporter substrate-binding protein
Asuc_0500	COG2115	Belongs to the xylose isomerase family
Asuc_0501	COG1070	Carbohydrate kinase
Asuc_0503	COG2502	aspartate--ammonia ligase
Asuc_0504	COG1522	sequence-specific DNA binding
Asuc_0505	COG0606	chelatase, subunit chli
Asuc_0506	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Asuc_0510	COG0425	Belongs to the sulfur carrier protein TusA family
Asuc_0511	COG1739	Uncharacterized protein family UPF0029
Asuc_0512	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Asuc_0514	COG1720	tRNA m6t6A37 methyltransferase activity
Asuc_0515	COG1575	Belongs to the MenA family. Type 1 subfamily
Asuc_0516	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Asuc_0517	COG0335	large ribosomal subunit rRNA binding
Asuc_0518	COG0336	Belongs to the RNA methyltransferase TrmD family
Asuc_0519	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Asuc_0520	COG0228	four-way junction DNA binding
Asuc_0523	COG4783	chaperone-mediated protein folding
Asuc_0525	COG0254	rRNA binding
Asuc_0527	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Asuc_0528	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Asuc_0529	COG1309	transcriptional regulator
Asuc_0530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Asuc_0531	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Asuc_0532	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Asuc_0533	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Asuc_0534	COG3719	Belongs to the RNase T2 family
Asuc_0535	COG0126	phosphoglycerate kinase activity
Asuc_0536	COG0191	fructose-bisphosphate aldolase activity
Asuc_0537	COG3307	-O-antigen
Asuc_0538	COG3171	Protein conserved in bacteria
Asuc_0539	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Asuc_0540	COG1194	a g-specific adenine glycosylase
Asuc_0541	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Asuc_0542	COG0741	lytic transglycosylase activity
Asuc_0543	COG3013	Belongs to the UPF0304 family
Asuc_0544	COG2853	Lipoprotein
Asuc_0547	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Asuc_0548	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Asuc_0549	COG0673	inositol 2-dehydrogenase activity
Asuc_0553	COG1902	pentaerythritol trinitrate reductase activity
Asuc_0554	COG0095	Lipoate-protein ligase
Asuc_0555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Asuc_0557	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Asuc_0558	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Asuc_0559	COG1388	LysM domain
Asuc_0559	COG4942	peptidase
Asuc_0561	COG1238	metal cluster binding
Asuc_0562	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Asuc_0563	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Asuc_0564	COG0346	lactoylglutathione lyase activity
Asuc_0565	COG0583	DNA-binding transcription factor activity
Asuc_0566	COG0758	DNA mediated transformation
Asuc_0567	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Asuc_0569	COG5413	integral membrane protein
Asuc_0570	COG2861	carbohydrate metabolic process
Asuc_0571	COG4942	peptidase
Asuc_0572	COG0588	phosphoglycerate mutase activity
Asuc_0573	COG0859	PFAM glycosyl transferase family 9
Asuc_0575	COG3022	response to hydroperoxide
Asuc_0576	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Asuc_0577	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
Asuc_0578	COG0481	GTPase activity
Asuc_0579	COG0681	Belongs to the peptidase S26 family
Asuc_0580	COG0571	ribonuclease III activity
Asuc_0581	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Asuc_0582	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Asuc_0583	COG3711	transcriptional antiterminator
Asuc_0583	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Asuc_0585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Asuc_0585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0586	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Asuc_0587	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Asuc_0587	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0587	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Asuc_0589	COG2183	response to ionizing radiation
Asuc_0591	COG1012	belongs to the aldehyde dehydrogenase family
Asuc_0591	COG1454	alcohol dehydrogenase
Asuc_0592	COG0584	glycerophosphoryl diester phosphodiesterase
Asuc_0593	COG2271	Major facilitator Superfamily
Asuc_0594	COG2095	MarC family integral membrane protein
Asuc_0597	COG3056	Lipoprotein
Asuc_0598	COG0271	Belongs to the BolA IbaG family
Asuc_0599	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Asuc_0601	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Asuc_0602	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Asuc_0603	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Asuc_0604	COG2871	sodium ion transport
Asuc_0605	COG1477	protein flavinylation
Asuc_0606	COG2991	Protein conserved in bacteria
Asuc_0607	COG0482	sulfurtransferase activity
Asuc_0610	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Asuc_0611	COG1459	type II secretion system
Asuc_0612	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Asuc_0613	COG4969	Belongs to the N-Me-Phe pilin family
Asuc_0614	COG3023	N-Acetylmuramoyl-L-alanine amidase
Asuc_0616	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asuc_0617	COG4160	amino acid transport
Asuc_0618	COG4215	(ABC) transporter
Asuc_0619	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asuc_0620	COG1126	abc transporter atp-binding protein
Asuc_0621	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Asuc_0623	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Asuc_0624	COG0813	purine-nucleoside phosphorylase activity
Asuc_0625	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Asuc_0626	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Asuc_0627	COG2364	Membrane
Asuc_0628	COG0814	amino acid
Asuc_0629	COG2226	methyltransferase
Asuc_0633	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asuc_0634	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Asuc_0634	COG0131	Imidazoleglycerol-phosphate dehydratase
Asuc_0636	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Asuc_0639	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Asuc_0640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Asuc_0641	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Asuc_0642	COG0511	ligase activity, forming carbon-carbon bonds
Asuc_0643	COG0439	Biotin carboxylase
Asuc_0644	COG3924	membrane
Asuc_0645	COG4145	pantothenate transmembrane transporter activity
Asuc_0646	COG2264	protein methyltransferase activity
Asuc_0647	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Asuc_0648	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Asuc_0650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Asuc_0652	COG2267	carboxylic ester hydrolase activity
Asuc_0653	COG2194	sulfuric ester hydrolase activity
Asuc_0654	COG0753	catalase activity
Asuc_0655	COG0528	UMP kinase activity
Asuc_0656	COG0233	cytoplasmic translational termination
Asuc_0657	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Asuc_0658	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Asuc_0659	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Asuc_0661	COG0006	proline dipeptidase activity
Asuc_0662	COG0459	protein refolding
Asuc_0663	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Asuc_0664	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asuc_0665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asuc_0666	COG0805	protein transport
Asuc_0669	COG0280	phosphate acetyltransferase
Asuc_0669	COG0281	malic enzyme
Asuc_0670	COG1187	pseudouridine synthase activity
Asuc_0671	COG2814	Major facilitator Superfamily
Asuc_0675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Asuc_0676	COG1519	Transferase
Asuc_0678	COG0456	acetyltransferase
Asuc_0679	COG0545	Peptidyl-prolyl cis-trans isomerase
Asuc_0680	COG2900	Belongs to the SlyX family
Asuc_0681	COG5645	(Lipo)protein
Asuc_0682	COG0210	DNA helicase
Asuc_0683	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asuc_0684	COG0110	maltose O-acetyltransferase activity
Asuc_0685	COG1854	S-ribosylhomocysteine lyase activity
Asuc_0686	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Asuc_0687	COG0205	6-phosphofructokinase activity
Asuc_0688	COG4796	Type ii and iii secretion system protein
Asuc_0692	COG4972	Pilus assembly protein
Asuc_0693	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Asuc_0694	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Asuc_0695	COG0799	negative regulation of ribosome biogenesis
Asuc_0696	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Asuc_0697	COG0768	penicillin binding
Asuc_0698	COG0772	Belongs to the SEDS family
Asuc_0699	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Asuc_0699	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Asuc_0700	COG1686	Belongs to the peptidase S11 family
Asuc_0701	COG2921	Belongs to the UPF0250 family
Asuc_0702	COG0321	lipoyl(octanoyl) transferase activity
Asuc_0703	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Asuc_0704	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Asuc_0705	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Asuc_0706	COG0437	4 iron, 4 sulfur cluster binding
Asuc_0707	COG3301	Polysulphide reductase, NrfD
Asuc_0708	COG1138	Cytochrome C-type biogenesis protein
Asuc_0709	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asuc_0710	COG3088	subunit of a heme lyase
Asuc_0710	COG4235	cytochrome complex assembly
Asuc_0711	COG3088	subunit of a heme lyase
Asuc_0711	COG4235	cytochrome complex assembly
Asuc_0712	COG2081	HI0933 family
Asuc_0713	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Asuc_0714	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Asuc_0715	COG3610	response to peptide
Asuc_0716	COG2966	Psort location CytoplasmicMembrane, score
Asuc_0717	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Asuc_0718	COG0545	Peptidyl-prolyl cis-trans isomerase
Asuc_0721	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Asuc_0723	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Asuc_0724	COG0590	tRNA wobble adenosine to inosine editing
Asuc_0725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Asuc_0727	COG0730	response to heat
Asuc_0728	COG0494	nUDIX hydrolase
Asuc_0729	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Asuc_0730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Asuc_0731	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Asuc_0732	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Asuc_0733	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Asuc_0734	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Asuc_0736	COG1305	Transglutaminase-like
Asuc_0738	COG2608	mercury ion transmembrane transporter activity
Asuc_0743	COG0495	leucyl-tRNA aminoacylation
Asuc_0745	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
Asuc_0746	COG1466	dna polymerase III delta subunit
Asuc_0747	COG1115	amino acid carrier protein
Asuc_0748	COG1349	DNA-binding transcription factor activity
Asuc_0749	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asuc_0750	COG2814	Major facilitator Superfamily
Asuc_0751	COG4536	flavin adenine dinucleotide binding
Asuc_0752	COG4137	Cytochrome C assembly protein
Asuc_0753	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Asuc_0754	COG2964	Protein conserved in bacteria
Asuc_0755	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Asuc_0757	COG2168	tRNA wobble position uridine thiolation
Asuc_0758	COG0359	binds to the 23S rRNA
Asuc_0759	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Asuc_0760	COG2965	DNA replication, synthesis of RNA primer
Asuc_0761	COG0360	Binds together with S18 to 16S ribosomal RNA
Asuc_0762	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Asuc_0763	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Asuc_0764	COG1652	LysM domain
Asuc_0765	COG0544	peptidyl-prolyl cis-trans isomerase activity
Asuc_0766	COG0740	serine-type endopeptidase activity
Asuc_0767	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Asuc_0768	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Asuc_0769	COG1686	Belongs to the peptidase S11 family
Asuc_0770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Asuc_0774	COG0052	Belongs to the universal ribosomal protein uS2 family
Asuc_0775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Asuc_0776	COG0402	S-adenosylhomocysteine deaminase activity
Asuc_0777	COG3083	sulfuric ester hydrolase activity
Asuc_0778	COG3082	Protein of unknown function (DUF1414)
Asuc_0779	COG3081	Nucleoid-associated protein
Asuc_0780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Asuc_0781	COG0745	RESPONSE REGULATOR receiver
Asuc_0782	COG2205	protein histidine kinase activity
Asuc_0783	COG0436	Aminotransferase
Asuc_0785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Asuc_0786	COG1127	ABC transporter
Asuc_0787	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Asuc_0788	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Asuc_0789	COG2854	intermembrane phospholipid transfer
Asuc_0790	COG3113	response to antibiotic
Asuc_0791	COG5007	Belongs to the BolA IbaG family
Asuc_0792	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asuc_0793	COG1122	ATPase activity
Asuc_0795	COG0310	cobalt ion transport
Asuc_0796	COG0310	cobalt ion transport
Asuc_0797	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
Asuc_0798	COG0789	Transcriptional regulator
Asuc_0799	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Asuc_0801	COG0527	aspartate kinase activity
Asuc_0801	COG0460	homoserine dehydrogenase
Asuc_0802	COG0083	homoserine kinase activity
Asuc_0803	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Asuc_0804	COG0754	glutathionylspermidine amidase activity
Asuc_0805	COG1393	Belongs to the ArsC family
Asuc_0806	COG1943	Transposase
Asuc_0807	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asuc_0808	COG1876	peptidase activity
Asuc_0809	COG3028	Belongs to the UPF0307 family
Asuc_0810	COG0312	modulator of DNA gyrase
Asuc_0811	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Asuc_0813	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
Asuc_0815	COG2244	polysaccharide biosynthetic process
Asuc_0821	COG0562	UDP-galactopyranose mutase
Asuc_0822	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asuc_0823	COG2755	lipolytic protein G-D-S-L family
Asuc_0823	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Asuc_0827	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
Asuc_0828	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
Asuc_0834	COG0105	UTP biosynthetic process
Asuc_0835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Asuc_0836	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Asuc_0837	COG3091	SprT-like family
Asuc_0839	COG0326	Molecular chaperone. Has ATPase activity
Asuc_0841	COG0494	nUDIX hydrolase
Asuc_0842	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Asuc_0843	COG4133	protoheme IX ABC transporter activity
Asuc_0844	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Asuc_0845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Asuc_0846	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Asuc_0847	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Asuc_0848	COG1138	Cytochrome C-type biogenesis protein
Asuc_0849	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asuc_0856	COG0726	polysaccharide deacetylase
Asuc_0856	COG1649	PFAM Uncharacterised BCR, COG1649
Asuc_0857	COG1215	transferase activity, transferring glycosyl groups
Asuc_0859	COG3064	Membrane
Asuc_0859	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Asuc_0859	COG3583	domain protein
Asuc_0860	COG0784	Response regulator, receiver
Asuc_0860	COG5002	protein histidine kinase activity
Asuc_0860	COG2198	Histidine kinase
Asuc_0860	COG5002	protein histidine kinase activity
Asuc_0860	COG2198	Histidine kinase
Asuc_0860	COG0784	Response regulator, receiver
Asuc_0862	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Asuc_0863	COG1959	2 iron, 2 sulfur cluster binding
Asuc_0864	COG1104	cysteine desulfurase activity
Asuc_0865	COG0822	iron-sulfur transferase activity
Asuc_0867	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Asuc_0868	COG0443	Heat shock 70 kDa protein
Asuc_0869	COG0633	Ferredoxin
Asuc_0870	COG2975	iron-sulfur cluster assembly
Asuc_0871	COG0572	uridine kinase
Asuc_0872	COG0717	Belongs to the dCTP deaminase family
Asuc_0876	COG0328	RNA-DNA hybrid ribonuclease activity
Asuc_0877	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Asuc_0878	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Asuc_0879	COG0745	RESPONSE REGULATOR receiver
Asuc_0880	COG2350	Protein conserved in bacteria
Asuc_0881	COG1607	acyl-coa hydrolase
Asuc_0882	COG2917	probably involved in intracellular septation
Asuc_0884	COG0497	DNA recombination
Asuc_0885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Asuc_0886	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Asuc_0887	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Asuc_0887	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asuc_0888	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asuc_0889	COG2610	gluconate transmembrane transporter activity
Asuc_0890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Asuc_0890	COG0116	Belongs to the methyltransferase superfamily
Asuc_0891	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Asuc_0891	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Asuc_0892	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Asuc_0892	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Asuc_0893	COG0517	IMP dehydrogenase activity
Asuc_0893	COG0516	GMP reductase activity
Asuc_0894	COG0697	spore germination
Asuc_0896	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Asuc_0896	COG0519	Catalyzes the synthesis of GMP from XMP
Asuc_0899	COG3381	protein complex oligomerization
Asuc_0901	COG1694	Mazg nucleotide pyrophosphohydrolase
Asuc_0904	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asuc_0905	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Asuc_0909	COG0500	methyltransferase
Asuc_0910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Asuc_0911	COG1530	ribonuclease E activity
Asuc_0915	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Asuc_0916	COG0142	geranyltranstransferase activity
Asuc_0917	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Asuc_0918	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Asuc_0919	COG0697	spore germination
Asuc_0920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Asuc_0921	COG2926	Belongs to the UPF0265 family
Asuc_0922	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Asuc_0923	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asuc_0924	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Asuc_0925	COG0527	aspartate kinase activity
Asuc_0926	COG3117	lipopolysaccharide transmembrane transporter activity
Asuc_0927	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Asuc_0928	COG1137	ATPase activity
Asuc_0929	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0930	COG1660	Displays ATPase and GTPase activities
Asuc_0931	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Asuc_0932	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
Asuc_0933	COG2813	Specifically methylates the guanine in position
Asuc_0936	COG3716	PTS system mannose fructose sorbose family IID component
Asuc_0937	COG3715	PTS system
Asuc_0938	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Asuc_0938	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0940	COG2252	PERMEase
Asuc_0942	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Asuc_0943	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asuc_0944	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asuc_0945	COG0791	NLP P60 protein
Asuc_0946	COG2932	Transcriptional regulator
Asuc_0947	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Asuc_0948	COG1119	ATPase activity
Asuc_0949	COG0330	HflC and HflK could
Asuc_0951	COG2249	NAD(P)H dehydrogenase (quinone) activity
Asuc_0952	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Asuc_0953	COG0795	lipopolysaccharide-transporting ATPase activity
Asuc_0954	COG0795	lipopolysaccharide-transporting ATPase activity
Asuc_0955	COG2268	Band 7 protein
Asuc_0957	COG3768	UPF0283 membrane protein
Asuc_0958	COG3283	Transcriptional regulator of aromatic amino acids metabolism
Asuc_0959	COG0735	belongs to the Fur family
Asuc_0960	COG0716	FMN binding
Asuc_0962	COG0596	Alpha beta hydrolase
Asuc_0963	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Asuc_0964	COG0318	PFAM AMP-dependent synthetase and ligase
Asuc_0965	COG3264	Mechanosensitive ion channel
Asuc_0965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Asuc_0966	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Asuc_0967	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
Asuc_0968	COG0730	response to heat
Asuc_0969	COG1560	Kdo2-lipid A biosynthetic process
Asuc_0970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Asuc_0971	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Asuc_0973	COG2723	6-phospho-beta-galactosidase activity
Asuc_0974	COG0561	phosphatase activity
Asuc_0975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Asuc_0975	COG1263	PTS System
Asuc_0975	COG2190	(PTS) system
Asuc_0977	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Asuc_0979	COG0187	DNA topoisomerase II activity
Asuc_0980	COG0488	(ABC) transporter
Asuc_0982	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Asuc_0983	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Asuc_0984	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asuc_0985	COG0137	argininosuccinate synthase activity
Asuc_0986	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Asuc_0987	COG1923	regulation of RNA biosynthetic process
Asuc_0988	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Asuc_0989	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Asuc_0990	COG0860	N-Acetylmuramoyl-L-alanine amidase
Asuc_0990	COG1388	LysM domain
Asuc_0991	COG0802	atpase or kinase
Asuc_0992	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Asuc_0993	COG1162	GTPase activity
Asuc_0994	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_0995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asuc_0996	COG2190	(PTS) system
Asuc_0997	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Asuc_0998	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Asuc_0999	COG3381	protein complex oligomerization
Asuc_1000	COG1289	transmembrane transporter activity
Asuc_1001	COG3304	Inner membrane component domain
Asuc_1002	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Asuc_1003	COG1254	Belongs to the acylphosphatase family
Asuc_1004	COG2920	part of a sulfur-relay system
Asuc_1007	COG3210	domain, Protein
Asuc_1016	COG1489	DNA binding
Asuc_1018	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asuc_1019	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Asuc_1020	COG1120	ATPase activity
Asuc_1021	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Asuc_1022	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Asuc_1023	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Asuc_1024	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asuc_1025	COG1758	RNA polymerase activity
Asuc_1026	COG0194	GDP metabolic process
Asuc_1027	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Asuc_1028	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asuc_1029	COG3112	Uncharacterised protein family (UPF0231)
Asuc_1030	COG0316	Belongs to the HesB IscA family
Asuc_1031	COG0024	Methionine aminopeptidase
Asuc_1032	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Asuc_1034	COG2217	Heavy metal translocating P-type atpase
Asuc_1036	COG0788	formyltetrahydrofolate deformylase activity
Asuc_1037	COG2916	Histone family protein nucleoid-structuring protein H-NS
Asuc_1038	COG1757	Na H antiporter
Asuc_1039	COG0028	Belongs to the TPP enzyme family
Asuc_1040	COG0440	acetolactate synthase activity
Asuc_1041	COG2194	sulfuric ester hydrolase activity
Asuc_1042	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Asuc_1044	COG0277	FAD linked oxidase domain protein
Asuc_1044	COG0247	lactate metabolic process
Asuc_1046	COG1704	LemA family
Asuc_1048	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Asuc_1050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Asuc_1051	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Asuc_1052	COG1862	Preprotein translocase
Asuc_1055	COG3945	hemerythrin HHE cation binding domain
Asuc_1056	COG0343	queuine tRNA-ribosyltransferase activity
Asuc_1057	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Asuc_1058	COG2927	DNA polymerase III (CHI subunit)
Asuc_1059	COG2153	protein acetylation
Asuc_1060	COG0525	valine-tRNA ligase activity
Asuc_1061	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asuc_1063	COG3069	C4-dicarboxylate transmembrane transporter activity
Asuc_1064	COG1473	amidohydrolase
Asuc_1066	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Asuc_1067	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Asuc_1068	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Asuc_1069	COG0330	HflC and HflK could
Asuc_1070	COG0330	HflC and HflK could
Asuc_1073	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Asuc_1074	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Asuc_1075	COG0617	tRNA 3'-terminal CCA addition
Asuc_1076	COG4991	sh3 domain protein
Asuc_1077	COG0306	phosphate transporter
Asuc_1078	COG1392	Phosphate transport regulator
Asuc_1079	COG3025	triphosphatase activity
Asuc_1080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Asuc_1081	COG3008	intermembrane lipid transfer
Asuc_1082	COG2995	paraquat-inducible protein a
Asuc_1083	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Asuc_1084	COG0793	Belongs to the peptidase S41A family
Asuc_1085	COG2989	Protein conserved in bacteria
Asuc_1086	COG3108	Peptidase M15
Asuc_1087	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asuc_1089	COG0556	nucleotide-excision repair
Asuc_1091	COG0484	heat shock protein binding
Asuc_1092	COG0443	Heat shock 70 kDa protein
Asuc_1094	COG0018	arginyl-trna synthetase
Asuc_1095	COG1946	Acyl-CoA thioesterase
Asuc_1096	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Asuc_1097	COG4988	ABC transporter
Asuc_1099	COG1522	sequence-specific DNA binding
Asuc_1101	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Asuc_1102	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Asuc_1103	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Asuc_1104	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Asuc_1106	COG0676	glucose-6-phosphate 1-epimerase activity
Asuc_1107	COG1199	ATP-dependent helicase activity
Asuc_1108	COG1214	PFAM Peptidase M22, glycoprotease
Asuc_1109	COG3065	identical protein binding
Asuc_1110	COG0318	PFAM AMP-dependent synthetase and ligase
Asuc_1111	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Asuc_1112	COG3102	Protein conserved in bacteria
Asuc_1114	COG3133	Outer membrane lipoprotein
Asuc_1115	COG4166	transmembrane transport
Asuc_1116	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Asuc_1117	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Asuc_1119	COG0779	Required for maturation of 30S ribosomal subunits
Asuc_1120	COG0195	Participates in both transcription termination and antitermination
Asuc_1121	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Asuc_1122	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Asuc_1123	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Asuc_1125	COG0037	tRNA processing
Asuc_1126	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Asuc_1127	COG0825	malonyl-CoA metabolic process
Asuc_1128	COG3955	Domain of unknown function (DUF1919)
Asuc_1129	COG4143	(ABC) transporter
Asuc_1130	COG1178	ABC-type Fe3 transport system permease component
Asuc_1131	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Asuc_1132	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Asuc_1134	COG0450	alkyl hydroperoxide reductase
Asuc_1135	COG0626	cystathionine gamma-synthase activity
Asuc_1136	COG1979	alcohol dehydrogenase
Asuc_1139	COG3093	addiction module antidote protein HigA
Asuc_1141	COG0842	Transport permease protein
Asuc_1142	COG0842	Transport permease protein
Asuc_1142	COG1129	ABC transporter
Asuc_1143	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Asuc_1146	COG2837	iron assimilation
Asuc_1147	COG0138	bifunctional purine biosynthesis protein purh
Asuc_1148	COG0151	Belongs to the GarS family
Asuc_1151	COG2707	UPF0756 membrane protein
Asuc_1152	COG1643	Atp-dependent helicase
Asuc_1153	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Asuc_1154	COG3265	gluconokinase activity
Asuc_1155	COG1063	alcohol dehydrogenase
Asuc_1156	COG1028	Short-chain dehydrogenase reductase Sdr
Asuc_1159	COG0385	Bile acid
Asuc_1160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asuc_1161	COG0405	Gamma-glutamyltransferase
Asuc_1163	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Asuc_1165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Asuc_1166	COG1609	Transcriptional regulator
Asuc_1167	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asuc_1168	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asuc_1169	COG2848	UPF0210 protein
Asuc_1171	COG0469	pyruvate kinase activity
Asuc_1172	COG4178	(ABC) transporter
Asuc_1173	COG4774	siderophore transport
Asuc_1175	COG0307	riboflavin synthase, alpha
Asuc_1179	COG2823	Periplasmic or secreted lipoprotein
Asuc_1180	COG2252	PERMEase
Asuc_1181	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Asuc_1182	COG1074	ATP-dependent DNA helicase activity
Asuc_1183	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Asuc_1184	COG2354	Protein conserved in bacteria
Asuc_1185	COG1944	ATP diphosphatase activity
Asuc_1186	COG2226	methyltransferase
Asuc_1187	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asuc_1188	COG1793	dna ligase
Asuc_1189	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Asuc_1190	COG0402	S-adenosylhomocysteine deaminase activity
Asuc_1191	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Asuc_1192	COG3047	cAMP biosynthetic process
Asuc_1193	COG1609	Transcriptional regulator
Asuc_1194	COG3052	prosthetic group binding
Asuc_1195	COG2301	Belongs to the HpcH HpaI aldolase family
Asuc_1196	COG3051	citrate lyase alpha subunit
Asuc_1197	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Asuc_1198	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Asuc_1198	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
Asuc_1199	COG0288	reversible hydration of carbon dioxide
Asuc_1200	COG1611	Belongs to the LOG family
Asuc_1201	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Asuc_1201	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Asuc_1202	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
Asuc_1203	COG3098	single-species biofilm formation
Asuc_1212	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Asuc_1236	COG4626	Terminase
Asuc_1236	COG1802	Transcriptional regulator
Asuc_1259	COG3099	Belongs to the UPF0263 family
Asuc_1260	COG0561	phosphatase activity
Asuc_1261	COG3058	Necessary for formate dehydrogenase activity
Asuc_1262	COG2864	formate dehydrogenase
Asuc_1263	COG0437	4 iron, 4 sulfur cluster binding
Asuc_1264	COG0243	molybdopterin cofactor binding
Asuc_1264	COG3383	formate dehydrogenase (NAD+) activity
Asuc_1265	COG3383	formate dehydrogenase (NAD+) activity
Asuc_1265	COG0243	molybdopterin cofactor binding
Asuc_1266	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Asuc_1267	COG1840	ABC-type Fe3 transport system, periplasmic component
Asuc_1268	COG0210	DNA helicase
Asuc_1269	COG0135	phosphoribosylanthranilate isomerase activity
Asuc_1269	COG0134	indole-3-glycerol-phosphate synthase activity
Asuc_1270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Asuc_1271	COG0512	Glutamine amidotransferase of anthranilate synthase
Asuc_1272	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Asuc_1273	COG1131	(ABC) transporter
Asuc_1274	COG0842	Transport permease protein
Asuc_1275	COG0616	signal peptide processing
Asuc_1277	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Asuc_1278	COG0437	4 iron, 4 sulfur cluster binding
Asuc_1279	COG5557	Pfam Polysulphide reductase, NrfD
Asuc_1280	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Asuc_1281	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Asuc_1282	COG1773	rubredoxin
Asuc_1283	COG0298	carbon dioxide binding
Asuc_1288	COG1518	maintenance of DNA repeat elements
Asuc_1288	COG1468	defense response to virus
Asuc_1290	COG1733	regulation of RNA biosynthetic process
Asuc_1292	COG1518	maintenance of DNA repeat elements
Asuc_1294	COG0017	Asparaginyl-tRNA synthetase
Asuc_1295	COG0302	gtp cyclohydrolase
Asuc_1296	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Asuc_1297	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Asuc_1298	COG0251	oxidation-reduction process
Asuc_1299	COG2964	Protein conserved in bacteria
Asuc_1300	COG1373	ATPase (AAA superfamily
Asuc_1301	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asuc_1303	COG2851	Citrate transporter
Asuc_1304	COG4221	oxidoreductase activity
Asuc_1313	COG0534	Mate efflux family protein
Asuc_1315	COG3550	peptidyl-serine autophosphorylation
Asuc_1318	COG0583	DNA-binding transcription factor activity
Asuc_1320	COG0640	Transcriptional regulator
Asuc_1321	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asuc_1324	COG0477	Major facilitator Superfamily
Asuc_1328	COG2999	glutathione oxidoreductase activity
Asuc_1329	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Asuc_1330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Asuc_1331	COG5039	Polysaccharide pyruvyl transferase
Asuc_1333	COG3306	glycosyltransferase involved in LPS biosynthesis
Asuc_1335	COG1216	Glycosyl transferase, family 2
Asuc_1336	COG1216	Glycosyl transferase, family 2
Asuc_1337	COG2951	lytic endotransglycosylase activity
Asuc_1339	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Asuc_1342	COG1560	Kdo2-lipid A biosynthetic process
Asuc_1343	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Asuc_1343	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Asuc_1344	COG1538	Outer membrane efflux protein
Asuc_1345	COG0577	efflux transmembrane transporter activity
Asuc_1345	COG1136	(ABC) transporter
Asuc_1346	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Asuc_1348	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Asuc_1350	COG2983	Belongs to the UPF0260 family
Asuc_1351	COG1640	4-alpha-glucanotransferase
Asuc_1352	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Asuc_1353	COG1523	belongs to the glycosyl hydrolase 13 family
Asuc_1354	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Asuc_1355	COG0297	glycogen (starch) synthase activity
Asuc_1357	COG2382	esterase
Asuc_1359	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Asuc_1360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Asuc_1361	COG3326	Membrane
Asuc_1363	COG0745	RESPONSE REGULATOR receiver
Asuc_1364	COG0642	Histidine kinase
Asuc_1365	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Asuc_1366	COG1881	PFAM PEBP family protein
Asuc_1367	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Asuc_1368	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asuc_1368	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asuc_1369	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asuc_1370	COG4667	esterase of the alpha-beta hydrolase superfamily
Asuc_1372	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Asuc_1373	COG0142	geranyltranstransferase activity
Asuc_1374	COG1722	exodeoxyribonuclease VII activity
Asuc_1377	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Asuc_1378	COG0303	'Molybdopterin
Asuc_1379	COG0708	Exodeoxyribonuclease III
Asuc_1380	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
Asuc_1381	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Asuc_1382	COG0285	dihydrofolate synthase activity
Asuc_1383	COG0406	alpha-ribazole phosphatase activity
Asuc_1384	COG0308	aminopeptidase N
Asuc_1385	COG0167	dihydroorotate dehydrogenase activity
Asuc_1387	COG0778	Nitroreductase
Asuc_1388	COG2171	N-acyltransferase activity
Asuc_1390	COG3100	YcgL domain-containing protein
Asuc_1391	COG3392	D12 class N6 adenine-specific DNA methyltransferase
Asuc_1393	COG2801	Transposase and inactivated derivatives
Asuc_1394	COG3423	Transcriptional regulator
Asuc_1395	COG2932	Transcriptional regulator
Asuc_1397	COG2211	Major facilitator Superfamily
Asuc_1399	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Asuc_1400	COG2925	Exonuclease
Asuc_1401	COG3422	double-strand break repair
Asuc_1402	COG0697	spore germination
Asuc_1403	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Asuc_1404	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
Asuc_1405	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
Asuc_1406	COG0037	tRNA processing
Asuc_1407	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Asuc_1407	COG1328	CTP reductase activity
Asuc_1409	COG0602	queuosine metabolic process
Asuc_1410	COG3700	Belongs to the class B bacterial acid phosphatase family
Asuc_1411	COG0084	hydrolase, TatD family'
Asuc_1412	COG0193	aminoacyl-tRNA hydrolase activity
Asuc_1413	COG0012	GTP binding
Asuc_1416	COG0531	amino acid
Asuc_1417	COG0791	NLP P60 protein
Asuc_1418	COG0776	regulation of translation
Asuc_1419	COG0072	phenylalanine-tRNA ligase activity
Asuc_1421	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Asuc_1422	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asuc_1423	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Asuc_1425	COG0166	Belongs to the GPI family
Asuc_1426	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Asuc_1427	COG0305	Participates in initiation and elongation during chromosome replication
Asuc_1428	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Asuc_1429	COG4591	ABC-type transport system involved in lipoprotein release permease component
Asuc_1430	COG1136	(ABC) transporter
Asuc_1431	COG4591	ABC-type transport system involved in lipoprotein release permease component
Asuc_1432	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asuc_1433	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Asuc_1435	COG2890	protein-(glutamine-N5) methyltransferase activity
Asuc_1436	COG1714	RDD family
Asuc_1438	COG2062	phosphohistidine phosphatase, SixA
Asuc_1439	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asuc_1439	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Asuc_1439	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asuc_1440	COG1461	Dihydroxyacetone kinase
Asuc_1441	COG2376	Dihydroxyacetone kinase
Asuc_1442	COG0456	acetyltransferase
Asuc_1443	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Asuc_1444	COG1067	ATP-dependent peptidase activity
Asuc_1446	COG1278	Cold shock
Asuc_1447	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Asuc_1448	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Asuc_1449	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Asuc_1450	COG5339	Protein conserved in bacteria
Asuc_1451	COG3101	peptidyl-lysine hydroxylation
Asuc_1452	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Asuc_1453	COG3593	DNA synthesis involved in DNA repair
Asuc_1454	COG2431	L-lysine efflux transmembrane transporter activity
Asuc_1456	COG2027	D-alanyl-D-alanine carboxypeptidase
Asuc_1457	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Asuc_1458	COG1534	Rna-binding protein
Asuc_1459	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asuc_1460	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Asuc_1461	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Asuc_1462	COG0792	nuclease activity
Asuc_1463	COG3107	peptidoglycan biosynthetic process
Asuc_1465	COG1609	Transcriptional regulator
Asuc_1466	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Asuc_1467	COG0823	Involved in the tonB-independent uptake of proteins
Asuc_1470	COG1917	Cupin 2, conserved barrel domain protein
Asuc_1471	COG0800	Aldolase
Asuc_1472	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asuc_1474	COG1028	Short-chain dehydrogenase reductase Sdr
Asuc_1478	COG0133	tryptophan synthase activity
Asuc_1479	COG0159	tryptophan synthase activity
Asuc_1480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Asuc_1481	COG0633	Ferredoxin
Asuc_1482	COG0471	metal ion transport
Asuc_1483	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Asuc_1484	COG1280	lysine exporter protein (LysE YggA)
Asuc_1485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Asuc_1486	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Asuc_1487	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Asuc_1488	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Asuc_1489	COG0814	amino acid
Asuc_1490	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Asuc_1491	COG2969	positive regulation of protein catabolic process
Asuc_1493	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Asuc_1494	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Asuc_1495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Asuc_1496	COG0076	glutamate decarboxylase activity
Asuc_1497	COG3105	Protein conserved in bacteria
Asuc_1499	COG0309	Hydrogenase expression formation protein (HypE)
Asuc_1500	COG0409	Hydrogenase expression formation protein
Asuc_1501	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Asuc_1502	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asuc_1503	COG0671	phosphoesterase, PA-phosphatase related
Asuc_1504	COG1940	carbohydrate kinase activity
Asuc_1505	COG2315	Protein conserved in bacteria
Asuc_1506	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Asuc_1507	COG0351	phosphomethylpyrimidine kinase
Asuc_1508	COG0352	thiamine-phosphate diphosphorylase activity
Asuc_1509	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Asuc_1510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Asuc_1511	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asuc_1512	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Asuc_1513	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asuc_1515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Asuc_1516	COG0375	protein maturation
Asuc_1519	COG2221	Nitrite and sulphite reductase 4Fe-4S
Asuc_1519	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Asuc_1520	COG3381	protein complex oligomerization
Asuc_1521	COG3302	dmso reductase anchor subunit
Asuc_1522	COG0437	4 iron, 4 sulfur cluster binding
Asuc_1523	COG0243	molybdopterin cofactor binding
Asuc_1524	COG0243	molybdopterin cofactor binding
Asuc_1526	COG1176	ABC-type spermidine putrescine transport system, permease component I
Asuc_1527	COG1175	transmembrane transport
Asuc_1528	COG3842	ATPase activity
Asuc_1532	COG2249	NAD(P)H dehydrogenase (quinone) activity
Asuc_1534	COG4221	oxidoreductase activity
Asuc_1535	COG0667	Aldo Keto reductase
Asuc_1536	COG0583	DNA-binding transcription factor activity
Asuc_1542	COG0583	DNA-binding transcription factor activity
Asuc_1545	COG0583	DNA-binding transcription factor activity
Asuc_1546	COG0778	Nitroreductase
Asuc_1547	COG0023	Translation Initiation Factor
Asuc_1548	COG0284	orotidine-5'-phosphate decarboxylase activity
Asuc_1549	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Asuc_1550	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Asuc_1551	COG0776	regulation of translation
Asuc_1552	COG0539	negative regulation of cytoplasmic translation
Asuc_1553	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Asuc_1554	COG2990	Protein conserved in bacteria
Asuc_1555	COG0741	lytic transglycosylase activity
Asuc_1556	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
Asuc_1557	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asuc_1559	COG0725	ABC transporter, periplasmic molybdate-binding protein
Asuc_1560	COG2005	Transcriptional regulator
Asuc_1561	COG2050	protein possibly involved in aromatic compounds catabolism
Asuc_1564	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Asuc_1565	COG0045	succinate-CoA ligase (ADP-forming) activity
Asuc_1566	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asuc_1567	COG0567	Dehydrogenase, E1 component
Asuc_1568	COG0471	metal ion transport
Asuc_1569	COG1605	Chorismate mutase
Asuc_1569	COG0287	Prephenate dehydrogenase
Asuc_1570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Asuc_1571	COG0616	signal peptide processing
Asuc_1572	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Asuc_1573	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Asuc_1574	COG1448	Aminotransferase
Asuc_1577	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Asuc_1579	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Asuc_1580	COG0698	ribose 5-phosphate isomerase
Asuc_1581	COG2390	Transcriptional regulator
Asuc_1583	COG3618	amidohydrolase
Asuc_1584	COG2271	Major facilitator Superfamily
Asuc_1585	COG1461	Dihydroxyacetone kinase
Asuc_1586	COG2376	Dihydroxyacetone kinase
Asuc_1588	COG0339	signal peptide processing
Asuc_1589	COG3118	belongs to the thioredoxin family
Asuc_1590	COG0492	ferredoxin-NADP+ reductase activity
Asuc_1595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Asuc_1597	COG0698	ribose 5-phosphate isomerase
Asuc_1598	COG3395	kinase activity
Asuc_1599	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Asuc_1603	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Asuc_1604	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asuc_1605	COG2914	Belongs to the UPF0125 (RnfH) family
Asuc_1607	COG1528	Iron-storage protein
Asuc_1608	COG1528	Iron-storage protein
Asuc_1610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asuc_1611	COG0589	response to stress
Asuc_1612	COG0039	L-malate dehydrogenase activity
Asuc_1613	COG1438	arginine binding
Asuc_1614	COG1090	epimerase
Asuc_1615	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Asuc_1616	COG1346	cytolysis
Asuc_1617	COG1380	Effector of murein hydrolase LrgA
Asuc_1618	COG1525	nuclease
Asuc_1620	COG2166	iron-sulfur cluster assembly
Asuc_1624	COG1028	Short-chain dehydrogenase reductase Sdr
Asuc_1625	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Asuc_1631	COG0583	DNA-binding transcription factor activity
Asuc_1633	COG2076	Multidrug Resistance protein
Asuc_1634	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Asuc_1637	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Asuc_1641	COG3645	SOS response
Asuc_1648	COG1764	response to oxidative stress
Asuc_1650	COG2315	Protein conserved in bacteria
Asuc_1652	COG2193	ferroxidase activity
Asuc_1653	COG1902	pentaerythritol trinitrate reductase activity
Asuc_1660	COG2207	Transcriptional regulator
Asuc_1661	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Asuc_1662	COG0280	phosphate acetyltransferase
Asuc_1662	COG0857	belongs to the CobB CobQ family
Asuc_1663	COG0672	)-iron permease
Asuc_1666	COG0577	efflux transmembrane transporter activity
Asuc_1668	COG1136	(ABC) transporter
Asuc_1668	COG0577	efflux transmembrane transporter activity
Asuc_1671	COG0517	IMP dehydrogenase activity
Asuc_1671	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Asuc_1672	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Asuc_1673	COG3094	Invasion gene expression up-regulator, SirB
Asuc_1674	COG0314	molybdopterin synthase activity
Asuc_1675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Asuc_1676	COG0315	cyclic pyranopterin monophosphate synthase activity
Asuc_1677	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Asuc_1678	COG1687	branched-chain amino acid
Asuc_1679	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Asuc_1680	COG0583	DNA-binding transcription factor activity
Asuc_1681	COG1840	ABC-type Fe3 transport system, periplasmic component
Asuc_1682	COG1840	ABC-type Fe3 transport system, periplasmic component
Asuc_1686	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Asuc_1687	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Asuc_1688	COG2895	sulfate adenylyltransferase (ATP) activity
Asuc_1689	COG0175	sulfate reduction
Asuc_1691	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Asuc_1691	COG1648	precorrin-2 dehydrogenase activity
Asuc_1692	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Asuc_1693	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Asuc_1694	COG4208	sulfate ABC transporter
Asuc_1695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Asuc_1696	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Asuc_1697	COG0583	DNA-binding transcription factor activity
Asuc_1698	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Asuc_1699	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Asuc_1700	COG0583	DNA-binding transcription factor activity
Asuc_1702	COG0009	L-threonylcarbamoyladenylate synthase
Asuc_1703	COG1609	Transcriptional regulator
Asuc_1704	COG3383	formate dehydrogenase (NAD+) activity
Asuc_1706	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Asuc_1709	COG1286	toxin biosynthetic process
Asuc_1711	COG0101	tRNA pseudouridine synthase activity
Asuc_1712	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Asuc_1713	COG0586	Pfam SNARE associated Golgi protein
Asuc_1715	COG3842	ATPase activity
Asuc_1716	COG1178	ABC-type Fe3 transport system permease component
Asuc_1717	COG3842	ATPase activity
Asuc_1719	COG1840	ABC-type Fe3 transport system, periplasmic component
Asuc_1724	COG0322	excinuclease ABC activity
Asuc_1726	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Asuc_1727	COG1663	tetraacyldisaccharide 4'-kinase activity
Asuc_1728	COG1132	(ABC) transporter
Asuc_1729	COG2333	competence protein COMEC
Asuc_1729	COG0658	competence protein
Asuc_1730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Asuc_1731	COG0617	tRNA 3'-terminal CCA addition
Asuc_1732	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Asuc_1733	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Asuc_1734	COG2949	membrane
Asuc_1737	COG4656	Part of a membrane complex involved in electron transport
Asuc_1738	COG4658	electron transport chain
Asuc_1741	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Asuc_1742	COG0733	neurotransmitter:sodium symporter activity
Asuc_1743	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Asuc_1744	COG1177	transmembrane transport
Asuc_1745	COG1176	ABC-type spermidine putrescine transport system, permease component I
Asuc_1746	COG3842	ATPase activity
Asuc_1748	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asuc_1748	COG0301	tRNA thio-modification
Asuc_1750	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Asuc_1751	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Asuc_1753	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Asuc_1754	COG4172	Belongs to the ABC transporter superfamily
Asuc_1755	COG4172	Belongs to the ABC transporter superfamily
Asuc_1756	COG4171	peptide transport system, permease
Asuc_1757	COG4168	peptide transport system, permease
Asuc_1758	COG4166	transmembrane transport
Asuc_1759	COG3106	COG3106 Predicted ATPase
Asuc_1761	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Asuc_1762	COG4974	Belongs to the 'phage' integrase family
Asuc_1763	COG2937	Belongs to the GPAT DAPAT family
Asuc_1764	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Asuc_1765	COG2814	Major facilitator Superfamily
Asuc_1766	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Asuc_1767	COG2258	MOSC domain
Asuc_1768	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Asuc_1769	COG0107	imidazoleglycerol-phosphate synthase activity
Asuc_1770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Asuc_1770	COG0140	phosphoribosyl-ATP diphosphatase activity
Asuc_1771	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Asuc_1772	COG2233	PERMEase
Asuc_1773	COG0121	glutamine amidotransferase
Asuc_1774	COG0215	cysteine-tRNA ligase activity
Asuc_1775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Asuc_1777	COG2860	membrane
Asuc_1778	COG1408	metallophosphoesterase
Asuc_1779	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Asuc_1782	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Asuc_1783	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Asuc_1784	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Asuc_1785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Asuc_1788	COG4795	General secretion pathway protein
Asuc_1789	COG2165	general secretion pathway protein
Asuc_1791	COG0823	Involved in the tonB-independent uptake of proteins
Asuc_1793	COG0848	biopolymer transport protein
Asuc_1794	COG0811	peptide transport
Asuc_1795	COG0824	Thioesterase
Asuc_1796	COG1294	oxidase, subunit
Asuc_1797	COG1271	oxidase subunit
Asuc_1799	COG2255	four-way junction helicase activity
Asuc_1800	COG0632	four-way junction helicase activity
Asuc_1801	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Asuc_1803	COG0217	transcriptional regulatory protein
Asuc_1804	COG0494	nUDIX hydrolase
Asuc_1805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Asuc_1806	COG4106	trans-aconitate 2-methyltransferase activity
Asuc_1808	COG0346	lactoylglutathione lyase activity
Asuc_1809	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Asuc_1810	COG2056	Na+-H+ antiporter family
Asuc_1812	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Asuc_1813	COG1053	succinate dehydrogenase
Asuc_1814	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Asuc_1816	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Asuc_1818	COG2814	Major facilitator Superfamily
Asuc_1819	COG0563	adenylate kinase activity
Asuc_1820	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Asuc_1821	COG4604	ABC transporter, ATP-binding protein
Asuc_1822	COG4605	iron ion homeostasis
Asuc_1823	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asuc_1824	COG0739	heme binding
Asuc_1825	COG1121	(ABC) transporter
Asuc_1826	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Asuc_1828	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asuc_1830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Asuc_1831	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asuc_1831	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asuc_1832	COG0489	protein tyrosine kinase activity
Asuc_1834	COG1595	DNA-templated transcription, initiation
Asuc_1836	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asuc_1838	COG1530	ribonuclease E activity
Asuc_1842	COG4771	TonB-dependent receptor
Asuc_1846	COG0626	cystathionine gamma-synthase activity
Asuc_1847	COG4948	Mandelate Racemase Muconate Lactonizing
Asuc_1848	COG2610	gluconate transmembrane transporter activity
Asuc_1852	COG4948	Mandelate Racemase Muconate Lactonizing
Asuc_1853	COG0656	L-ascorbic acid biosynthetic process
Asuc_1855	COG2721	sulfolactate sulfo-lyase activity
Asuc_1856	COG3835	regulator
Asuc_1857	COG1929	Belongs to the glycerate kinase type-1 family
Asuc_1858	COG2084	Dehydrogenase
Asuc_1860	COG2974	May be involved in recombination
Asuc_1861	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Asuc_1862	COG0587	DNA-directed DNA polymerase activity
Asuc_1863	COG1253	flavin adenine dinucleotide binding
Asuc_1865	COG0084	hydrolase, TatD family'
Asuc_1866	COG0470	DNA polymerase III
Asuc_1867	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Asuc_1868	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Asuc_1869	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asuc_1870	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Asuc_1871	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Asuc_1872	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Asuc_1873	COG1555	photosystem II stabilization
Asuc_1874	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Asuc_1875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Asuc_1876	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Asuc_1877	COG0196	riboflavin kinase activity
Asuc_1878	COG0778	Nitroreductase
Asuc_1879	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Asuc_1880	COG0629	single-stranded DNA binding
Asuc_1883	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Asuc_1884	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Asuc_1886	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asuc_1887	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Asuc_1888	COG0628	permease
Asuc_1891	COG0521	Mo-molybdopterin cofactor biosynthetic process
Asuc_1892	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Asuc_1894	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Asuc_1895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Asuc_1896	COG4211	Belongs to the binding-protein-dependent transport system permease family
Asuc_1897	COG1129	ABC transporter
Asuc_1898	COG1879	ABC-type sugar transport system periplasmic component
Asuc_1899	COG1085	galactose-1-phosphate uridylyltransferase
Asuc_1900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Asuc_1901	COG2017	converts alpha-aldose to the beta-anomer
Asuc_1904	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Asuc_1908	COG0473	3-isopropylmalate dehydrogenase activity
Asuc_1909	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Asuc_1910	COG0066	3-isopropylmalate dehydratase activity
Asuc_1911	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Asuc_1912	COG1792	Involved in formation and maintenance of cell shape
Asuc_1913	COG1077	Cell shape determining protein MreB Mrl
Asuc_1914	COG0243	molybdopterin cofactor binding
Asuc_1915	COG3005	denitrification pathway
Asuc_1916	COG0243	molybdopterin cofactor binding
Asuc_1917	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Asuc_1918	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Asuc_1920	COG2824	Alkylphosphonate utilization operon protein PhnA
Asuc_1923	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Asuc_1924	COG1605	Chorismate mutase
Asuc_1924	COG0077	Prephenate dehydratase
Asuc_1925	COG0737	Belongs to the 5'-nucleotidase family
Asuc_1926	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Asuc_1927	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Asuc_1928	COG0849	cell division
Asuc_1929	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Asuc_1930	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asuc_1931	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Asuc_1932	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asuc_1934	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Asuc_1935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Asuc_1936	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Asuc_1937	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Asuc_1938	COG0768	penicillin binding
Asuc_1939	COG3116	cell division
Asuc_1940	COG0275	rRNA processing
Asuc_1941	COG2001	Belongs to the MraZ family
Asuc_1942	COG1966	Carbon starvation protein
Asuc_1944	COG1444	tRNA N-acetyltransferase activity
Asuc_1945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Asuc_1946	COG1702	phosphate starvation-inducible protein PhoH
Asuc_1947	COG2918	glutathione biosynthetic process
Asuc_1947	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asuc_1948	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asuc_1950	COG0765	amino acid transport
Asuc_1951	COG0765	amino acid transport
Asuc_1952	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asuc_1953	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Asuc_1954	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asuc_1955	COG1454	alcohol dehydrogenase
Asuc_1961	COG2731	YhcH YjgK YiaL family protein
Asuc_1962	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Asuc_1963	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Asuc_1965	COG0750	zinc metalloprotease
Asuc_1966	COG0575	Belongs to the CDS family
Asuc_1968	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Asuc_1970	COG1620	l-lactate permease
Asuc_1971	COG0247	lactate metabolic process
Asuc_1972	COG1139	Iron-sulfur cluster binding protein
Asuc_1973	COG1556	Lactate utilization protein
Asuc_1974	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Asuc_1975	COG1011	Hydrolase
Asuc_1976	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Asuc_1977	COG1872	DUF167
Asuc_1978	COG0762	integral membrane protein
Asuc_1979	COG0598	Magnesium transport protein CorA
Asuc_1980	COG1252	NADH dehydrogenase
Asuc_1981	COG2816	NAD+ diphosphatase activity
Asuc_1982	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Asuc_1983	COG3068	Protein conserved in bacteria
Asuc_1984	COG0776	regulation of translation
Asuc_1985	COG3642	lipopolysaccharide core region biosynthetic process
Asuc_1986	COG0859	PFAM glycosyl transferase family 9
Asuc_1987	COG0564	pseudouridine synthase activity
Asuc_1992	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Asuc_1994	COG1971	Probably functions as a manganese efflux pump
Asuc_1995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asuc_1999	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Asuc_2000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Asuc_2001	COG1028	Short-chain dehydrogenase reductase Sdr
Asuc_2002	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Asuc_2003	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asuc_2004	COG0416	fatty acid biosynthetic process
Asuc_2005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Asuc_2006	COG1399	metal-binding, possibly nucleic acid-binding protein
Asuc_2007	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Asuc_2008	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Asuc_2009	COG1811	Na channel or pump
Asuc_2011	COG0848	biopolymer transport protein
Asuc_2012	COG0811	peptide transport
Asuc_2013	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Asuc_2015	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Asuc_2016	COG2321	neutral zinc metallopeptidase
Asuc_2017	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Asuc_2018	COG0720	synthase
Asuc_2019	COG0602	queuosine metabolic process
Asuc_2020	COG0494	nUDIX hydrolase
Asuc_2021	COG0653	protein targeting
Asuc_2023	COG4701	Protein of unknown function (DUF721)
Asuc_2024	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asuc_2025	COG2976	Protein conserved in bacteria
Asuc_2026	COG0124	histidyl-tRNA synthetase
Asuc_2027	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Asuc_2028	COG1426	Protein conserved in bacteria
Asuc_2029	COG3063	Type IV pilus biogenesis stability protein PilW
Asuc_2030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Asuc_2031	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Asuc_2032	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Asuc_2033	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Asuc_2034	COG3005	denitrification pathway
Asuc_2035	COG3043	anaerobic respiration
Asuc_2036	COG0348	domain, Protein
Asuc_2037	COG0437	4 iron, 4 sulfur cluster binding
Asuc_2038	COG0243	molybdopterin cofactor binding
Asuc_2039	COG3062	negative regulation of establishment of protein localization
Asuc_2040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Asuc_2043	COG3036	rescue of stalled ribosome
Asuc_2045	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
Asuc_2046	COG1051	belongs to the nudix hydrolase family
Asuc_2050	COG1396	sequence-specific DNA binding
Asuc_2051	COG0148	phosphopyruvate hydratase activity
Asuc_2052	COG0504	CTP synthase activity
Asuc_2053	COG0585	pseudouridine synthase activity
Asuc_2054	COG1858	cytochrome C peroxidase
Asuc_2055	COG0789	Transcriptional regulator
Asuc_2057	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Asuc_2058	COG0659	secondary active sulfate transmembrane transporter activity
Asuc_2059	COG0513	Belongs to the DEAD box helicase family
Asuc_2060	COG4785	May be involved in cell division
Asuc_2061	COG1185	polyribonucleotide nucleotidyltransferase activity
Asuc_2062	COG2731	YhcH YjgK YiaL family protein
Asuc_2063	COG0557	exoribonuclease II activity
Asuc_2065	COG1435	thymidine kinase activity
Asuc_2067	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Asuc_2068	COG3115	cell septum assembly
Asuc_2070	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Asuc_2071	COG0204	Acyl-transferase
Asuc_2072	COG2132	Multicopper oxidase
Asuc_2073	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Asuc_2075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Asuc_2078	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asuc_2079	COG1733	regulation of RNA biosynthetic process
Asuc_2080	COG2267	carboxylic ester hydrolase activity
Asuc_2088	COG0667	Aldo Keto reductase
Asuc_2089	COG0656	L-ascorbic acid biosynthetic process
Asuc_2090	COG1373	ATPase (AAA superfamily
Asuc_2093	COG2272	Belongs to the type-B carboxylesterase lipase family
Asuc_2094	COG0667	Aldo Keto reductase
Asuc_2098	COG0454	-acetyltransferase
Asuc_2099	COG1064	alcohol dehydrogenase
Asuc_2100	COG2910	NAD(P)H-binding
Asuc_2105	COG3061	Opacity-associated protein A
Asuc_2105	COG3266	domain, Protein
Asuc_2106	COG1509	lysine 2,3-aminomutase activity
Asuc_2107	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Asuc_2108	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Asuc_2109	COG0728	peptidoglycan biosynthetic process
Asuc_2110	COG0268	Binds directly to 16S ribosomal RNA
Asuc_2112	COG0560	Phosphoserine phosphatase
Asuc_2113	COG1666	GTP binding
Asuc_2114	COG0706	membrane insertase activity
Asuc_2115	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Asuc_2116	COG0594	ribonuclease P activity
Asuc_2117	COG0230	Belongs to the bacterial ribosomal protein bL34 family