locus-tag	class	description
ASU1_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASU1_00010	COG0592	DNA-directed DNA polymerase activity
ASU1_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASU1_00025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASU1_00035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASU1_00040	COG0616	signal peptide processing
ASU1_00050	COG1114	Component of the transport system for branched-chain amino acids
ASU1_00055	COG1028	Short-chain dehydrogenase reductase Sdr
ASU1_00060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASU1_00065	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASU1_00070	COG0142	geranyltranstransferase activity
ASU1_00075	COG0431	NADPH-dependent FMN reductase
ASU1_00080	COG2259	Doxx family
ASU1_00085	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASU1_00090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASU1_00095	COG0697	spore germination
ASU1_00100	COG0697	spore germination
ASU1_00105	COG0295	cytidine deaminase activity
ASU1_00115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASU1_00120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASU1_00130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASU1_00135	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASU1_00140	COG0494	nUDIX hydrolase
ASU1_00145	COG1218	3'(2'),5'-bisphosphate nucleotidase
ASU1_00150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASU1_00155	COG0363	glucosamine-6-phosphate deaminase activity
ASU1_00160	COG2814	Major facilitator Superfamily
ASU1_00165	COG1794	racemase activity, acting on amino acids and derivatives
ASU1_00180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASU1_00195	COG3115	cell septum assembly
ASU1_00200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASU1_00215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASU1_00255	COG2814	Major facilitator Superfamily
ASU1_00285	COG1090	epimerase
ASU1_00290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASU1_00295	COG1127	ABC transporter
ASU1_00300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU1_00305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASU1_00310	COG2854	intermembrane phospholipid transfer
ASU1_00320	COG5007	Belongs to the BolA IbaG family
ASU1_00325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASU1_00340	COG0488	(ABC) transporter
ASU1_00345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASU1_00355	COG2166	iron-sulfur cluster assembly
ASU1_00360	COG0740	serine-type endopeptidase activity
ASU1_00365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASU1_00370	COG1663	tetraacyldisaccharide 4'-kinase activity
ASU1_00375	COG2835	tetraacyldisaccharide 4'-kinase activity
ASU1_00440	COG0582	viral genome integration into host DNA
ASU1_00455	COG3063	Type IV pilus biogenesis stability protein PilW
ASU1_00460	COG2183	response to ionizing radiation
ASU1_00475	COG1252	NADH dehydrogenase
ASU1_00485	COG3719	Belongs to the RNase T2 family
ASU1_00490	COG0616	signal peptide processing
ASU1_00495	COG0778	Nitroreductase
ASU1_00500	COG0300	oxidoreductase activity
ASU1_00510	COG2217	Heavy metal translocating P-type atpase
ASU1_00520	COG0789	Transcriptional regulator
ASU1_00550	COG0745	RESPONSE REGULATOR receiver
ASU1_00555	COG5002	protein histidine kinase activity
ASU1_00560	COG0187	DNA topoisomerase II activity
ASU1_00565	COG0471	metal ion transport
ASU1_00570	COG0471	metal ion transport
ASU1_00575	COG0471	metal ion transport
ASU1_00580	COG0126	phosphoglycerate kinase activity
ASU1_00585	COG0191	fructose-bisphosphate aldolase activity
ASU1_00590	COG4172	Belongs to the ABC transporter superfamily
ASU1_00605	COG0778	Nitroreductase
ASU1_00615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASU1_00625	COG1943	Transposase
ASU1_00630	COG0084	hydrolase, TatD family'
ASU1_00635	COG1966	Carbon starvation protein
ASU1_00640	COG1640	4-alpha-glucanotransferase
ASU1_00645	COG3833	ABC-type maltose transport systems, permease component
ASU1_00660	COG3842	ATPase activity
ASU1_00665	COG4580	involved in the transport of maltose and maltodextrins
ASU1_00675	COG2909	trisaccharide binding
ASU1_00680	COG0058	SHG alpha-glucan phosphorylase activity
ASU1_00690	COG1666	GTP binding
ASU1_00695	COG0560	Phosphoserine phosphatase
ASU1_00705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASU1_00710	COG2081	HI0933 family
ASU1_00715	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASU1_00720	COG2252	PERMEase
ASU1_00725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASU1_00730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASU1_00740	COG0716	FMN binding
ASU1_00745	COG0735	belongs to the Fur family
ASU1_00750	COG3008	intermembrane lipid transfer
ASU1_00755	COG1854	S-ribosylhomocysteine lyase activity
ASU1_00760	COG1132	(ABC) transporter
ASU1_00765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASU1_00775	COG3318	Belongs to the UPF0149 family
ASU1_00775	COG3012	SEC-C Motif Domain Protein
ASU1_00780	COG0673	inositol 2-dehydrogenase activity
ASU1_00785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASU1_00820	COG1426	Protein conserved in bacteria
ASU1_00825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASU1_00835	COG2976	Protein conserved in bacteria
ASU1_00840	COG3201	nicotinamide mononucleotide transporter
ASU1_00855	COG2965	DNA replication, synthesis of RNA primer
ASU1_00870	COG2841	Protein conserved in bacteria
ASU1_00875	COG2268	Band 7 protein
ASU1_00880	COG1609	Transcriptional regulator
ASU1_00885	COG2226	methyltransferase
ASU1_00890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASU1_00895	COG0512	Glutamine amidotransferase of anthranilate synthase
ASU1_00900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASU1_00905	COG2837	iron assimilation
ASU1_00910	COG0009	L-threonylcarbamoyladenylate synthase
ASU1_00915	COG1187	pseudouridine synthase activity
ASU1_00920	COG0583	DNA-binding transcription factor activity
ASU1_00925	COG3266	domain, Protein
ASU1_00955	COG0612	Peptidase, M16
ASU1_00965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASU1_00975	COG0217	transcriptional regulatory protein
ASU1_00980	COG0494	nUDIX hydrolase
ASU1_00995	COG0402	S-adenosylhomocysteine deaminase activity
ASU1_01000	COG4143	(ABC) transporter
ASU1_01005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASU1_01010	COG0617	tRNA 3'-terminal CCA addition
ASU1_01015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASU1_01025	COG2911	Protein conserved in bacteria
ASU1_01035	COG0346	lactoylglutathione lyase activity
ASU1_01040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASU1_01050	COG0477	Major facilitator Superfamily
ASU1_01055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASU1_01065	COG0475	glutathione-regulated potassium exporter activity
ASU1_01065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASU1_01070	COG1138	Cytochrome C-type biogenesis protein
ASU1_01075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASU1_01080	COG3088	subunit of a heme lyase
ASU1_01080	COG4235	cytochrome complex assembly
ASU1_01085	COG4235	cytochrome complex assembly
ASU1_01095	COG0748	coenzyme F420 binding
ASU1_01100	COG4771	TonB-dependent receptor
ASU1_01100	COG1629	transport
ASU1_01105	COG1605	Chorismate mutase
ASU1_01105	COG0077	Prephenate dehydratase
ASU1_01110	COG0339	signal peptide processing
ASU1_01120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASU1_01125	COG1882	Formate acetyltransferase
ASU1_01130	COG2116	formate transmembrane transporter activity
ASU1_01135	COG1238	metal cluster binding
ASU1_01140	COG0501	Belongs to the peptidase M48B family
ASU1_01150	COG2431	L-lysine efflux transmembrane transporter activity
ASU1_01160	COG0436	Aminotransferase
ASU1_01170	COG2962	Rard protein
ASU1_01175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASU1_01180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASU1_01190	COG2089	acid synthase
ASU1_01215	COG3306	glycosyltransferase involved in LPS biosynthesis
ASU1_01225	COG1216	Glycosyl transferase, family 2
ASU1_01230	COG1216	Glycosyl transferase, family 2
ASU1_01240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASU1_01250	COG0813	purine-nucleoside phosphorylase activity
ASU1_01255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASU1_01265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASU1_01280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASU1_01285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASU1_01290	COG0083	homoserine kinase activity
ASU1_01295	COG0527	aspartate kinase activity
ASU1_01295	COG0460	homoserine dehydrogenase
ASU1_01305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASU1_01310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASU1_01315	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASU1_01320	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ASU1_01325	COG0194	GDP metabolic process
ASU1_01330	COG1538	Outer membrane efflux protein
ASU1_01335	COG2914	Belongs to the UPF0125 (RnfH) family
ASU1_01340	COG2867	negative regulation of translational initiation
ASU1_01345	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASU1_01350	COG4149	molybdate abc transporter
ASU1_01355	COG0725	ABC transporter, periplasmic molybdate-binding protein
ASU1_01360	COG0842	Transport permease protein
ASU1_01365	COG1131	(ABC) transporter
ASU1_01375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASU1_01380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASU1_01385	COG1121	(ABC) transporter
ASU1_01395	COG2920	part of a sulfur-relay system
ASU1_01400	COG0670	Belongs to the BI1 family
ASU1_01405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASU1_01425	COG3118	belongs to the thioredoxin family
ASU1_01430	COG0330	HflC and HflK could
ASU1_01435	COG0330	HflC and HflK could
ASU1_01445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASU1_01445	COG0301	tRNA thio-modification
ASU1_01455	COG0424	maF-like protein
ASU1_01460	COG2252	PERMEase
ASU1_01465	COG1528	Iron-storage protein
ASU1_01470	COG1528	Iron-storage protein
ASU1_01475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASU1_01480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASU1_01485	COG1862	Preprotein translocase
ASU1_01490	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ASU1_01500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASU1_01520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASU1_01525	COG1012	belongs to the aldehyde dehydrogenase family
ASU1_01525	COG1454	alcohol dehydrogenase
ASU1_01530	COG0181	hydroxymethylbilane synthase activity
ASU1_01535	COG1587	Uroporphyrinogen-III synthase
ASU1_01540	COG2959	enzyme of heme biosynthesis
ASU1_01545	COG3071	HemY protein
ASU1_01550	COG2354	Protein conserved in bacteria
ASU1_01555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASU1_01565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASU1_01570	COG2095	MarC family integral membrane protein
ASU1_01575	COG4166	transmembrane transport
ASU1_01580	COG0489	protein tyrosine kinase activity
ASU1_01590	COG2017	converts alpha-aldose to the beta-anomer
ASU1_01600	COG1085	galactose-1-phosphate uridylyltransferase
ASU1_01610	COG0642	Histidine kinase
ASU1_01615	COG0745	RESPONSE REGULATOR receiver
ASU1_01625	COG3111	PFAM Bacterial OB fold (BOF) protein
ASU1_01640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASU1_01650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASU1_01655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASU1_01660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASU1_01675	COG1253	flavin adenine dinucleotide binding
ASU1_01680	COG0564	pseudouridine synthase activity
ASU1_01685	COG0588	phosphoglycerate mutase activity
ASU1_01690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASU1_01695	COG1678	Uncharacterized ACR, COG1678
ASU1_01700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASU1_01710	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASU1_01715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASU1_01720	COG1408	metallophosphoesterase
ASU1_01725	COG0753	catalase activity
ASU1_01735	COG0626	cystathionine gamma-synthase activity
ASU1_01740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASU1_01755	COG1702	phosphate starvation-inducible protein PhoH
ASU1_01765	COG0254	rRNA binding
ASU1_01785	COG0583	DNA-binding transcription factor activity
ASU1_01790	COG0708	Exodeoxyribonuclease III
ASU1_01795	COG2056	Na+-H+ antiporter family
ASU1_01805	COG0037	tRNA processing
ASU1_01810	COG3092	negative regulation of chromosome organization
ASU1_01825	COG1607	acyl-coa hydrolase
ASU1_01830	COG2350	Protein conserved in bacteria
ASU1_01845	COG0786	glutamate:sodium symporter activity
ASU1_01865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASU1_01870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASU1_01875	COG0138	bifunctional purine biosynthesis protein purh
ASU1_01880	COG1444	tRNA N-acetyltransferase activity
ASU1_01895	COG2801	Transposase and inactivated derivatives
ASU1_01915	COG2027	D-alanyl-D-alanine carboxypeptidase
ASU1_01920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASU1_01930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASU1_01935	COG0156	8-amino-7-oxononanoate synthase activity
ASU1_01940	COG2830	Protein of unknown function (DUF452)
ASU1_01945	COG2226	methyltransferase
ASU1_01950	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASU1_01955	COG2840	Smr protein MutS2
ASU1_01960	COG0697	spore germination
ASU1_01965	COG0784	Response regulator, receiver
ASU1_01965	COG2198	Histidine kinase
ASU1_01965	COG5002	protein histidine kinase activity
ASU1_01970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASU1_01980	COG1959	2 iron, 2 sulfur cluster binding
ASU1_01985	COG1104	cysteine desulfurase activity
ASU1_01990	COG0822	iron-sulfur transferase activity
ASU1_02000	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASU1_02020	COG0633	Ferredoxin
ASU1_02025	COG2975	iron-sulfur cluster assembly
ASU1_02045	COG2801	Transposase and inactivated derivatives
ASU1_02050	COG2963	transposase activity
ASU1_02055	COG0617	tRNA 3'-terminal CCA addition
ASU1_02060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASU1_02065	COG0215	cysteine-tRNA ligase activity
ASU1_02070	COG2160	L-arabinose isomerase activity
ASU1_02085	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASU1_02090	COG1129	ABC transporter
ASU1_02095	COG1879	ABC-type sugar transport system periplasmic component
ASU1_02100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASU1_02125	COG0583	DNA-binding transcription factor activity
ASU1_02135	COG0110	maltose O-acetyltransferase activity
ASU1_02145	COG3642	lipopolysaccharide core region biosynthetic process
ASU1_02150	COG0302	gtp cyclohydrolase
ASU1_02160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASU1_02165	COG1560	Kdo2-lipid A biosynthetic process
ASU1_02170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASU1_02185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASU1_02195	COG1704	LemA family
ASU1_02205	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ASU1_02205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASU1_02205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASU1_02210	COG1105	Belongs to the carbohydrate kinase PfkB family
ASU1_02215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU1_02215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU1_02225	COG1523	belongs to the glycosyl hydrolase 13 family
ASU1_02235	COG0297	glycogen (starch) synthase activity
ASU1_02240	COG0058	SHG alpha-glucan phosphorylase activity
ASU1_02245	COG0105	UTP biosynthetic process
ASU1_02260	COG1441	menaquinone biosynthetic process
ASU1_02270	COG2814	Major facilitator Superfamily
ASU1_02280	COG3381	protein complex oligomerization
ASU1_02290	COG0791	NLP P60 protein
ASU1_02295	COG2932	Transcriptional regulator
ASU1_02300	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ASU1_02305	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASU1_02320	COG1643	Atp-dependent helicase
ASU1_02325	COG2707	UPF0756 membrane protein
ASU1_02335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASU1_02340	COG0534	Mate efflux family protein
ASU1_02345	COG1074	ATP-dependent DNA helicase activity
ASU1_02350	COG1396	sequence-specific DNA binding
ASU1_02355	COG3550	peptidyl-serine autophosphorylation
ASU1_02360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASU1_02365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASU1_02370	COG1328	CTP reductase activity
ASU1_02375	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASU1_02390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASU1_02395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASU1_02400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASU1_02405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASU1_02410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASU1_02425	COG0750	zinc metalloprotease
ASU1_02430	COG0575	Belongs to the CDS family
ASU1_02435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASU1_02440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASU1_02450	COG0671	phosphoesterase, PA-phosphatase related
ASU1_02455	COG1534	Rna-binding protein
ASU1_02460	COG0463	Glycosyl transferase, family 2
ASU1_02465	COG1686	Belongs to the peptidase S11 family
ASU1_02470	COG0859	PFAM glycosyl transferase family 9
ASU1_02480	COG0328	RNA-DNA hybrid ribonuclease activity
ASU1_02485	COG1286	toxin biosynthetic process
ASU1_02490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASU1_02515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASU1_02520	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASU1_02530	COG0251	oxidation-reduction process
ASU1_02540	COG0582	viral genome integration into host DNA
ASU1_02580	COG3728	DNA packaging
ASU1_02610	COG5645	(Lipo)protein
ASU1_02625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASU1_02635	COG1792	Involved in formation and maintenance of cell shape
ASU1_02640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASU1_02645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASU1_02650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASU1_02655	COG0121	glutamine amidotransferase
ASU1_02670	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASU1_02675	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASU1_02680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASU1_02685	COG0045	succinate-CoA ligase (ADP-forming) activity
ASU1_02690	COG2990	Protein conserved in bacteria
ASU1_02695	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASU1_02700	COG0567	Dehydrogenase, E1 component
ASU1_02705	COG1121	(ABC) transporter
ASU1_02710	COG0739	heme binding
ASU1_02715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASU1_02720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASU1_02730	COG0561	phosphatase activity
ASU1_02735	COG3850	Histidine kinase
ASU1_02745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASU1_02750	COG0393	Putative heavy-metal-binding
ASU1_02755	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ASU1_02760	COG2983	Belongs to the UPF0260 family
ASU1_02765	COG4221	oxidoreductase activity
ASU1_02770	COG0133	tryptophan synthase activity
ASU1_02785	COG1199	ATP-dependent helicase activity
ASU1_02790	COG1380	Effector of murein hydrolase LrgA
ASU1_02795	COG1346	cytolysis
ASU1_02800	COG1132	(ABC) transporter
ASU1_02805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASU1_02810	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASU1_02815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASU1_02820	COG0167	dihydroorotate dehydrogenase activity
ASU1_02825	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASU1_02830	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASU1_02835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASU1_02850	COG0737	Belongs to the 5'-nucleotidase family
ASU1_02855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASU1_02860	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ASU1_02890	COG2226	methyltransferase
ASU1_02895	COG3036	rescue of stalled ribosome
ASU1_02940	COG4626	Terminase
ASU1_02940	COG1802	Transcriptional regulator
ASU1_03000	COG0582	viral genome integration into host DNA
ASU1_03005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASU1_03010	COG1346	cytolysis
ASU1_03015	COG1380	Effector of murein hydrolase LrgA
ASU1_03035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASU1_03040	COG2226	methyltransferase
ASU1_03045	COG0596	Alpha beta hydrolase
ASU1_03050	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ASU1_03055	COG0318	PFAM AMP-dependent synthetase and ligase
ASU1_03060	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ASU1_03060	COG3264	Mechanosensitive ion channel
ASU1_03065	COG3264	Mechanosensitive ion channel
ASU1_03065	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ASU1_03075	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ASU1_03080	COG1785	Belongs to the alkaline phosphatase family
ASU1_03090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASU1_03100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASU1_03105	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASU1_03110	COG0539	negative regulation of cytoplasmic translation
ASU1_03115	COG0776	regulation of translation
ASU1_03120	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ASU1_03125	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASU1_03130	COG0284	orotidine-5'-phosphate decarboxylase activity
ASU1_03135	COG0023	Translation Initiation Factor
ASU1_03140	COG3787	Belongs to the UPF0306 family
ASU1_03145	COG1811	Na channel or pump
ASU1_03155	COG3094	Invasion gene expression up-regulator, SirB
ASU1_03160	COG3028	Belongs to the UPF0307 family
ASU1_03165	COG0312	modulator of DNA gyrase
ASU1_03170	COG0440	acetolactate synthase activity
ASU1_03175	COG0028	Belongs to the TPP enzyme family
ASU1_03180	COG0288	reversible hydration of carbon dioxide
ASU1_03185	COG1278	Cold shock
ASU1_03195	COG0343	queuine tRNA-ribosyltransferase activity
ASU1_03200	COG3945	hemerythrin HHE cation binding domain
ASU1_03210	COG4991	sh3 domain protein
ASU1_03215	COG0306	phosphate transporter
ASU1_03220	COG1392	Phosphate transport regulator
ASU1_03225	COG4604	ABC transporter, ATP-binding protein
ASU1_03230	COG4605	iron ion homeostasis
ASU1_03235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU1_03240	COG4607	ABC-type enterochelin transport system periplasmic component
ASU1_03245	COG0305	Participates in initiation and elongation during chromosome replication
ASU1_03250	COG3100	YcgL domain-containing protein
ASU1_03255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASU1_03260	COG0527	aspartate kinase activity
ASU1_03270	COG0248	Ppx GppA phosphatase
ASU1_03275	COG2731	YhcH YjgK YiaL family protein
ASU1_03280	COG1737	Transcriptional regulator
ASU1_03285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASU1_03300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASU1_03300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASU1_03305	COG0583	DNA-binding transcription factor activity
ASU1_03315	COG1444	tRNA N-acetyltransferase activity
ASU1_03320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASU1_03325	COG0314	molybdopterin synthase activity
ASU1_03330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ASU1_03335	COG0315	cyclic pyranopterin monophosphate synthase activity
ASU1_03345	COG3005	denitrification pathway
ASU1_03350	COG0243	molybdopterin cofactor binding
ASU1_03355	COG2363	Small membrane protein
ASU1_03365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASU1_03370	COG0626	cystathionine gamma-synthase activity
ASU1_03375	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ASU1_03380	COG0741	lytic transglycosylase activity
ASU1_03390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASU1_03395	COG0538	isocitrate dehydrogenase activity
ASU1_03400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASU1_03410	COG1509	lysine 2,3-aminomutase activity
ASU1_03415	COG0017	Asparaginyl-tRNA synthetase
ASU1_03420	COG2925	Exonuclease
ASU1_03430	COG0613	PHP domain protein
ASU1_03440	COG2837	iron assimilation
ASU1_03450	COG0556	nucleotide-excision repair
ASU1_03465	COG0006	proline dipeptidase activity
ASU1_03470	COG1448	Aminotransferase
ASU1_03475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASU1_03485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASU1_03490	COG0625	glutathione transferase activity
ASU1_03495	COG2969	positive regulation of protein catabolic process
ASU1_03505	COG0589	response to stress
ASU1_03515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASU1_03530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASU1_03550	COG0737	Belongs to the 5'-nucleotidase family
ASU1_03560	COG0280	phosphate acetyltransferase
ASU1_03560	COG0857	belongs to the CobB CobQ family
ASU1_03570	COG0277	FAD linked oxidase domain protein
ASU1_03575	COG2951	lytic endotransglycosylase activity
ASU1_03580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASU1_03585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASU1_03590	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASU1_03595	COG0195	Participates in both transcription termination and antitermination
ASU1_03600	COG0779	Required for maturation of 30S ribosomal subunits
ASU1_03605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASU1_03610	COG1943	Transposase
ASU1_03620	COG0732	type I restriction modification DNA specificity domain
ASU1_03625	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ASU1_03630	COG0285	dihydrofolate synthase activity
ASU1_03640	COG3956	TIGRFAM MazG family protein
ASU1_03645	COG0745	RESPONSE REGULATOR receiver
ASU1_03650	COG2205	protein histidine kinase activity
ASU1_03655	COG1136	(ABC) transporter
ASU1_03655	COG0577	efflux transmembrane transporter activity
ASU1_03660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASU1_03665	COG1494	fructose-1,6-bisphosphatase
ASU1_03670	COG3074	FtsZ-dependent cytokinesis
ASU1_03675	COG1435	thymidine kinase activity
ASU1_03685	COG1214	PFAM Peptidase M22, glycoprotease
ASU1_03690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASU1_03695	COG2321	neutral zinc metallopeptidase
ASU1_03700	COG1674	ftsk spoiiie
ASU1_03705	COG1522	sequence-specific DNA binding
ASU1_03710	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASU1_03715	COG1940	carbohydrate kinase activity
ASU1_03715	COG1846	Transcriptional regulator
ASU1_03720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASU1_03725	COG0791	NLP P60 protein
ASU1_03730	COG0776	regulation of translation
ASU1_03735	COG0072	phenylalanine-tRNA ligase activity
ASU1_03740	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASU1_03745	COG0778	Nitroreductase
ASU1_03750	COG1823	symporter activity
ASU1_03755	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ASU1_03780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASU1_03785	COG3105	Protein conserved in bacteria
ASU1_03795	COG0814	amino acid
ASU1_03800	COG0814	amino acid
ASU1_03805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASU1_03810	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASU1_03815	COG0517	IMP dehydrogenase activity
ASU1_03815	COG0516	GMP reductase activity
ASU1_03840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASU1_03845	COG3955	Domain of unknown function (DUF1919)
ASU1_03855	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASU1_03860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASU1_03865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASU1_03870	COG1309	transcriptional regulator
ASU1_03880	COG3083	sulfuric ester hydrolase activity
ASU1_03885	COG2828	Protein conserved in bacteria
ASU1_03890	COG0471	metal ion transport
ASU1_03895	COG2188	Transcriptional regulator
ASU1_03905	COG2814	Major facilitator Superfamily
ASU1_03915	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ASU1_03925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASU1_03930	COG1185	polyribonucleotide nucleotidyltransferase activity
ASU1_03935	COG4785	May be involved in cell division
ASU1_03940	COG0513	Belongs to the DEAD box helicase family
ASU1_03945	COG0590	tRNA wobble adenosine to inosine editing
ASU1_03955	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ASU1_03960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASU1_03965	COG0233	cytoplasmic translational termination
ASU1_03970	COG0528	UMP kinase activity
ASU1_03975	COG2194	sulfuric ester hydrolase activity
ASU1_03990	COG4178	(ABC) transporter
ASU1_03995	COG4774	siderophore transport
ASU1_04005	COG1840	ABC-type Fe3 transport system, periplasmic component
ASU1_04010	COG0433	COG0433 Predicted ATPase
ASU1_04045	COG4964	Belongs to the GSP D family
ASU1_04100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASU1_04105	COG0571	ribonuclease III activity
ASU1_04110	COG0681	Belongs to the peptidase S26 family
ASU1_04115	COG0481	GTPase activity
ASU1_04125	COG0351	phosphomethylpyrimidine kinase
ASU1_04140	COG1115	amino acid carrier protein
ASU1_04145	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ASU1_04150	COG3683	transport system, periplasmic component
ASU1_04160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASU1_04165	COG0280	phosphate acetyltransferase
ASU1_04165	COG0281	malic enzyme
ASU1_04170	COG0471	metal ion transport
ASU1_04175	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ASU1_04175	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ASU1_04180	COG3051	citrate lyase alpha subunit
ASU1_04185	COG2301	Belongs to the HpcH HpaI aldolase family
ASU1_04190	COG3052	prosthetic group binding
ASU1_04200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASU1_04205	COG0189	ligase activity
ASU1_04215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASU1_04225	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASU1_04230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASU1_04230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASU1_04245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASU1_04250	COG0629	single-stranded DNA binding
ASU1_04260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ASU1_04275	COG0477	Major facilitator Superfamily
ASU1_04280	COG3676	manually curated
ASU1_04290	COG0583	DNA-binding transcription factor activity
ASU1_04300	COG1028	Short-chain dehydrogenase reductase Sdr
ASU1_04300	COG3321	synthase
ASU1_04300	COG0604	alcohol dehydrogenase
ASU1_04320	COG2070	2-Nitropropane dioxygenase
ASU1_04325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASU1_04335	COG1368	sulfuric ester hydrolase activity
ASU1_04340	COG3217	Mosc domain protein beta barrel domain protein
ASU1_04340	COG0633	Ferredoxin
ASU1_04345	COG1722	exodeoxyribonuclease VII activity
ASU1_04350	COG0142	geranyltranstransferase activity
ASU1_04360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASU1_04365	COG1530	ribonuclease E activity
ASU1_04370	COG1944	ATP diphosphatase activity
ASU1_04385	COG0500	methyltransferase
ASU1_04395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASU1_04410	COG0305	Participates in initiation and elongation during chromosome replication
ASU1_04440	COG0629	single-stranded DNA binding
ASU1_04460	COG0798	PFAM Bile acid sodium symporter
ASU1_04465	COG0798	PFAM Bile acid sodium symporter
ASU1_04470	COG0789	Transcriptional regulator
ASU1_04480	COG0798	PFAM Bile acid sodium symporter
ASU1_04485	COG0789	Transcriptional regulator
ASU1_04500	COG2217	Heavy metal translocating P-type atpase
ASU1_04510	COG2132	Multicopper oxidase
ASU1_04525	COG0667	Aldo Keto reductase
ASU1_04540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASU1_04750	COG4172	Belongs to the ABC transporter superfamily
ASU1_04755	COG4171	peptide transport system, permease
ASU1_04760	COG4168	peptide transport system, permease
ASU1_04765	COG4166	transmembrane transport
ASU1_04770	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ASU1_04775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASU1_04780	COG1879	ABC-type sugar transport system periplasmic component
ASU1_04785	COG1757	Na H antiporter
ASU1_04790	COG2916	Histone family protein nucleoid-structuring protein H-NS
ASU1_04795	COG1620	l-lactate permease
ASU1_04800	COG0247	lactate metabolic process
ASU1_04805	COG1139	Iron-sulfur cluster binding protein
ASU1_04810	COG1556	Lactate utilization protein
ASU1_04815	COG2949	membrane
ASU1_04820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASU1_04830	COG0586	Pfam SNARE associated Golgi protein
ASU1_04835	COG0187	DNA topoisomerase II activity
ASU1_04840	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASU1_04845	COG1349	DNA-binding transcription factor activity
ASU1_04850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASU1_04855	COG2915	High frequency lysogenization protein hflD homolog
ASU1_04865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASU1_04870	COG4988	ABC transporter
ASU1_04875	COG2911	Protein conserved in bacteria
ASU1_04880	COG0729	surface antigen
ASU1_04885	COG2861	carbohydrate metabolic process
ASU1_04890	COG4942	peptidase
ASU1_04895	COG0588	phosphoglycerate mutase activity
ASU1_04900	COG1279	arginine transmembrane transporter activity
ASU1_04905	COG0572	uridine kinase
ASU1_04910	COG0717	Belongs to the dCTP deaminase family
ASU1_04915	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASU1_04920	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASU1_04925	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ASU1_04940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASU1_04945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASU1_04950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASU1_04955	COG4166	transmembrane transport
ASU1_04965	COG0444	Belongs to the ABC transporter superfamily
ASU1_04970	COG4608	Belongs to the ABC transporter superfamily
ASU1_04975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASU1_04980	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASU1_04985	COG0747	negative chemotaxis
ASU1_04990	COG0814	amino acid
ASU1_04995	COG1760	l-serine dehydratase
ASU1_05005	COG0134	indole-3-glycerol-phosphate synthase activity
ASU1_05005	COG0135	phosphoribosylanthranilate isomerase activity
ASU1_05010	COG3177	Filamentation induced by cAMP protein fic
ASU1_05015	COG3098	single-species biofilm formation
ASU1_05020	COG0564	pseudouridine synthase activity
ASU1_05025	COG3140	Belongs to the UPF0181 family
ASU1_05035	COG3025	triphosphatase activity
ASU1_05040	COG3106	COG3106 Predicted ATPase
ASU1_05050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASU1_05060	COG3069	C4-dicarboxylate transmembrane transporter activity
ASU1_05065	COG3340	Belongs to the peptidase S51 family
ASU1_05075	COG0495	leucyl-tRNA aminoacylation
ASU1_05080	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ASU1_05085	COG1466	dna polymerase III delta subunit
ASU1_05090	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ASU1_05095	COG0237	dephospho-CoA kinase activity
ASU1_05105	COG1459	type II secretion system
ASU1_05110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASU1_05115	COG4969	Belongs to the N-Me-Phe pilin family
ASU1_05120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASU1_05130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASU1_05130	COG0517	IMP dehydrogenase activity
ASU1_05160	COG0247	lactate metabolic process
ASU1_05165	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ASU1_05170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASU1_05175	COG0584	glycerophosphoryl diester phosphodiesterase
ASU1_05180	COG2271	Major facilitator Superfamily
ASU1_05190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASU1_05200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASU1_05210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU1_05215	COG1160	GTP binding
ASU1_05220	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ASU1_05220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASU1_05225	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ASU1_05230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASU1_05235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASU1_05240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASU1_05245	COG0318	PFAM AMP-dependent synthetase and ligase
ASU1_05255	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ASU1_05260	COG1595	DNA-templated transcription, initiation
ASU1_05270	COG0561	phosphatase activity
ASU1_05275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASU1_05280	COG0385	Bile acid
ASU1_05285	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ASU1_05295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASU1_05300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASU1_05305	COG0730	response to heat
ASU1_05310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASU1_05325	COG5339	Protein conserved in bacteria
ASU1_05335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASU1_05340	COG3383	formate dehydrogenase (NAD+) activity
ASU1_05340	COG0243	molybdopterin cofactor binding
ASU1_05345	COG0243	molybdopterin cofactor binding
ASU1_05345	COG3383	formate dehydrogenase (NAD+) activity
ASU1_05350	COG0437	4 iron, 4 sulfur cluster binding
ASU1_05355	COG2864	formate dehydrogenase
ASU1_05360	COG3058	Necessary for formate dehydrogenase activity
ASU1_05365	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASU1_05370	COG3117	lipopolysaccharide transmembrane transporter activity
ASU1_05375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ASU1_05380	COG1137	ATPase activity
ASU1_05385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU1_05390	COG1660	Displays ATPase and GTPase activities
ASU1_05395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASU1_05415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASU1_05440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASU1_05445	COG0631	protein serine/threonine phosphatase activity
ASU1_05470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASU1_05490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASU1_05500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASU1_05505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASU1_05510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASU1_05515	COG3023	N-Acetylmuramoyl-L-alanine amidase
ASU1_05520	COG0564	pseudouridine synthase activity
ASU1_05535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASU1_05540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASU1_05545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASU1_05550	COG0303	'Molybdopterin
ASU1_05555	COG2095	MarC family integral membrane protein
ASU1_05575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASU1_05585	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASU1_05595	COG0823	Involved in the tonB-independent uptake of proteins
ASU1_05600	COG3064	Membrane
ASU1_05600	COG3064	Membrane
ASU1_05605	COG0848	biopolymer transport protein
ASU1_05610	COG0811	peptide transport
ASU1_05615	COG0824	Thioesterase
ASU1_05630	COG1294	oxidase, subunit
ASU1_05635	COG1271	oxidase subunit
ASU1_05655	COG0494	nUDIX hydrolase
ASU1_05690	COG0271	Belongs to the BolA IbaG family
ASU1_05715	COG4172	Belongs to the ABC transporter superfamily
ASU1_05720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASU1_05725	COG0601	transmembrane transport
ASU1_05730	COG2255	four-way junction helicase activity
ASU1_05740	COG1177	transmembrane transport
ASU1_05745	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASU1_05750	COG3842	ATPase activity
ASU1_05765	COG0210	DNA helicase
ASU1_05770	COG0084	hydrolase, TatD family'
ASU1_05785	COG0531	amino acid
ASU1_05790	COG0531	amino acid
ASU1_05805	COG3047	cAMP biosynthetic process
ASU1_05810	COG0542	response to heat
ASU1_05815	COG0798	PFAM Bile acid sodium symporter
ASU1_05820	COG0659	secondary active sulfate transmembrane transporter activity
ASU1_05825	COG1393	Belongs to the ArsC family
ASU1_05835	COG1027	Aspartate ammonia-lyase
ASU1_05845	COG2271	Major facilitator Superfamily
ASU1_05850	COG3851	Histidine kinase
ASU1_05855	COG2197	response regulator
ASU1_05860	COG2271	Major facilitator Superfamily
ASU1_05865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASU1_05870	COG3583	domain protein
ASU1_05870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ASU1_05870	COG3064	Membrane
ASU1_05880	COG0720	synthase
ASU1_05885	COG0602	queuosine metabolic process
ASU1_05890	COG2271	Major facilitator Superfamily
ASU1_05895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASU1_05910	COG0795	lipopolysaccharide-transporting ATPase activity
ASU1_05915	COG0795	lipopolysaccharide-transporting ATPase activity
ASU1_05930	COG1840	ABC-type Fe3 transport system, periplasmic component
ASU1_05945	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASU1_05955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASU1_05965	COG0861	Integral membrane protein TerC family
ASU1_05975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASU1_05980	COG0148	phosphopyruvate hydratase activity
ASU1_05985	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
ASU1_06005	COG1965	Belongs to the frataxin family
ASU1_06015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASU1_06020	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASU1_06025	COG0564	pseudouridine synthase activity
ASU1_06035	COG0205	6-phosphofructokinase activity
ASU1_06040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASU1_06050	COG1115	amino acid carrier protein
ASU1_06055	COG0628	permease
ASU1_06070	COG3307	-O-antigen
ASU1_06075	COG1519	Transferase
ASU1_06085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASU1_06090	COG0802	atpase or kinase
ASU1_06095	COG1388	LysM domain
ASU1_06095	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASU1_06105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASU1_06110	COG2062	phosphohistidine phosphatase, SixA
ASU1_06115	COG0469	pyruvate kinase activity
ASU1_06120	COG0859	PFAM glycosyl transferase family 9
ASU1_06125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASU1_06130	COG0287	Prephenate dehydrogenase
ASU1_06130	COG1605	Chorismate mutase
ASU1_06135	COG2801	Transposase and inactivated derivatives
ASU1_06140	COG2963	transposase activity
ASU1_06145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASU1_06155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASU1_06160	COG1280	lysine exporter protein (LysE YggA)
ASU1_06165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASU1_06170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASU1_06175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASU1_06180	COG4796	Type ii and iii secretion system protein
ASU1_06200	COG4972	Pilus assembly protein
ASU1_06205	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASU1_06210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASU1_06215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASU1_06220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ASU1_06225	COG0733	neurotransmitter:sodium symporter activity
ASU1_06230	COG0166	Belongs to the GPI family
ASU1_06235	COG2960	long-chain fatty acid transporting porin activity
ASU1_06240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASU1_06250	COG0551	DNA topoisomerase type I activity
ASU1_06260	COG2137	regulation of response to DNA damage stimulus
ASU1_06265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASU1_06270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASU1_06280	COG1322	Protein conserved in bacteria
ASU1_06285	COG0512	Glutamine amidotransferase of anthranilate synthase
ASU1_06295	COG1560	Kdo2-lipid A biosynthetic process
ASU1_06310	COG4658	electron transport chain
ASU1_06320	COG4656	Part of a membrane complex involved in electron transport
ASU1_06325	COG2878	Part of a membrane complex involved in electron transport
ASU1_06330	COG4657	Part of a membrane complex involved in electron transport
ASU1_06340	COG2274	protein secretion by the type I secretion system
ASU1_06360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASU1_06370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASU1_06375	COG2814	Major facilitator Superfamily
ASU1_06380	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ASU1_06390	COG2991	Protein conserved in bacteria
ASU1_06395	COG1477	protein flavinylation
ASU1_06400	COG2871	sodium ion transport
ASU1_06405	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASU1_06410	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASU1_06415	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASU1_06420	COG1805	sodium ion transport
ASU1_06425	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASU1_06430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASU1_06430	COG0316	Belongs to the HesB IscA family
ASU1_06435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ASU1_06440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASU1_06450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASU1_06455	COG1611	Belongs to the LOG family
ASU1_06460	COG3593	DNA synthesis involved in DNA repair
ASU1_06465	COG1254	Belongs to the acylphosphatase family
ASU1_06470	COG1929	Belongs to the glycerate kinase type-1 family
ASU1_06475	COG2610	gluconate transmembrane transporter activity
ASU1_06480	COG3835	regulator
ASU1_06485	COG4166	transmembrane transport
ASU1_06505	COG5413	integral membrane protein
ASU1_06515	COG0252	asparaginase activity
ASU1_06525	COG0583	DNA-binding transcription factor activity
ASU1_06530	COG1011	Hydrolase
ASU1_06535	COG0583	DNA-binding transcription factor activity
ASU1_06540	COG1162	GTPase activity
ASU1_06550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASU1_06555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASU1_06560	COG0537	adenosine 5'-monophosphoramidase activity
ASU1_06575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASU1_06580	COG3108	Peptidase M15
ASU1_06585	COG2989	Protein conserved in bacteria
ASU1_06590	COG0793	Belongs to the peptidase S41A family
ASU1_06595	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ASU1_06600	COG1278	Cold shock
ASU1_06605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASU1_06625	COG3068	Protein conserved in bacteria
ASU1_06640	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ASU1_06645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASU1_06650	COG1414	Transcriptional regulator
ASU1_06655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASU1_06715	COG2831	hemolysin activation secretion protein
ASU1_06725	COG3301	Polysulphide reductase, NrfD
ASU1_06730	COG0437	4 iron, 4 sulfur cluster binding
ASU1_06735	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ASU1_06745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASU1_06755	COG3978	acetolactate synthase activity
ASU1_06760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASU1_06765	COG0129	dihydroxy-acid dehydratase activity
ASU1_06785	COG3306	glycosyltransferase involved in LPS biosynthesis
ASU1_06790	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ASU1_06800	COG0006	proline dipeptidase activity
ASU1_06805	COG3030	protein affecting phage T7 exclusion by the F plasmid
ASU1_06825	COG3753	Protein conserved in bacteria
ASU1_06830	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASU1_06835	COG0492	ferredoxin-NADP+ reductase activity
ASU1_06840	COG2376	Dihydroxyacetone kinase
ASU1_06845	COG1461	Dihydroxyacetone kinase
ASU1_06850	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ASU1_06850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU1_06850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASU1_06855	COG3118	belongs to the thioredoxin family
ASU1_06865	COG0811	peptide transport
ASU1_06870	COG0848	biopolymer transport protein
ASU1_06875	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASU1_06880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASU1_06885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASU1_06890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASU1_06895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASU1_06900	COG0251	oxidation-reduction process
ASU1_06910	COG4608	Belongs to the ABC transporter superfamily
ASU1_06915	COG0444	Belongs to the ABC transporter superfamily
ASU1_06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASU1_06925	COG0601	transmembrane transport
ASU1_06930	COG0747	negative chemotaxis
ASU1_06935	COG0747	negative chemotaxis
ASU1_06945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASU1_06955	COG2197	response regulator
ASU1_06960	COG0366	Alpha amylase catalytic
ASU1_06965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASU1_06965	COG1263	PTS System
ASU1_06970	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASU1_06975	COG0354	folic acid binding
ASU1_06980	COG1561	YicC-like family, N-terminal region
ASU1_06990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASU1_07005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASU1_07010	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASU1_07020	COG0745	RESPONSE REGULATOR receiver
ASU1_07025	COG2129	metallophosphoesterase
ASU1_07030	COG3172	ATPase kinase involved in NAD metabolism
ASU1_07035	COG0196	riboflavin kinase activity
ASU1_07040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASU1_07045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASU1_07050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASU1_07065	COG0018	arginyl-trna synthetase
ASU1_07070	COG3102	Protein conserved in bacteria
ASU1_07075	COG3133	Outer membrane lipoprotein
ASU1_07095	COG0193	aminoacyl-tRNA hydrolase activity
ASU1_07120	COG0747	negative chemotaxis
ASU1_07125	COG0601	transmembrane transport
ASU1_07130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASU1_07135	COG4172	Belongs to the ABC transporter superfamily
ASU1_07140	COG0497	DNA recombination
ASU1_07145	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASU1_07150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASU1_07155	COG0849	cell division
ASU1_07165	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASU1_07175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASU1_07180	COG0772	Belongs to the SEDS family
ASU1_07185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASU1_07195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASU1_07200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASU1_07205	COG0768	penicillin binding
ASU1_07210	COG3116	cell division
ASU1_07215	COG0275	rRNA processing
ASU1_07220	COG2001	Belongs to the MraZ family
ASU1_07225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASU1_07230	COG3700	Belongs to the class B bacterial acid phosphatase family
ASU1_07245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASU1_07250	COG0549	Belongs to the carbamate kinase family
ASU1_07260	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ASU1_07265	COG1178	ABC-type Fe3 transport system permease component
ASU1_07270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU1_07275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASU1_07280	COG2190	(PTS) system
ASU1_07285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASU1_07290	COG3059	membrane
ASU1_07300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASU1_07305	COG1621	beta-fructofuranosidase activity
ASU1_07320	COG2391	methyltransferase activity
ASU1_07325	COG0425	Belongs to the sulfur carrier protein TusA family
ASU1_07330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASU1_07345	COG0308	aminopeptidase N
ASU1_07365	COG0805	protein transport
ASU1_07370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASU1_07375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASU1_07380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASU1_07390	COG2226	methyltransferase
ASU1_07395	COG0598	Magnesium transport protein CorA
ASU1_07405	COG3085	chromosome segregation
ASU1_07410	COG0076	glutamate decarboxylase activity
ASU1_07415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASU1_07425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASU1_07430	COG2003	Belongs to the UPF0758 family
ASU1_07435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASU1_07445	COG1309	transcriptional regulator
ASU1_07460	COG1694	Mazg nucleotide pyrophosphohydrolase
ASU1_07465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASU1_07470	COG1923	regulation of RNA biosynthetic process
ASU1_07480	COG1064	alcohol dehydrogenase
ASU1_07515	COG1490	D-aminoacyl-tRNA deacylase activity
ASU1_07525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASU1_07545	COG0494	nUDIX hydrolase
ASU1_07550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASU1_07555	COG0174	glutamine synthetase
ASU1_07560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASU1_07565	COG0594	ribonuclease P activity
ASU1_07570	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASU1_07580	COG2818	Glycosylase
ASU1_07590	COG1388	LysM domain
ASU1_07590	COG4942	peptidase
ASU1_07605	COG1238	metal cluster binding
ASU1_07610	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASU1_07620	COG0149	triose-phosphate isomerase activity
ASU1_07635	COG1215	transferase activity, transferring glycosyl groups
ASU1_07640	COG0726	polysaccharide deacetylase
ASU1_07640	COG1649	PFAM Uncharacterised BCR, COG1649
ASU1_07650	COG1022	Amp-dependent synthetase and ligase
ASU1_07660	COG0676	glucose-6-phosphate 1-epimerase activity
ASU1_07665	COG2853	Lipoprotein
ASU1_07670	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ASU1_07675	COG3924	membrane
ASU1_07680	COG4145	pantothenate transmembrane transporter activity
ASU1_07705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ASU1_07715	COG4208	sulfate ABC transporter
ASU1_07720	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASU1_07745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASU1_07750	COG2995	paraquat-inducible protein a
ASU1_07755	COG1305	Transglutaminase-like
ASU1_07765	COG2608	mercury ion transmembrane transporter activity
ASU1_07770	COG1012	belongs to the aldehyde dehydrogenase family
ASU1_07785	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ASU1_07790	COG1373	ATPase (AAA superfamily
ASU1_07815	COG1373	ATPase (AAA superfamily
ASU1_07850	COG2315	Protein conserved in bacteria
ASU1_07855	COG1764	response to oxidative stress
ASU1_07860	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASU1_07860	COG1902	pentaerythritol trinitrate reductase activity
ASU1_07865	COG0640	Transcriptional regulator
ASU1_07885	COG2207	Transcriptional regulator
ASU1_07890	COG0778	Nitroreductase
ASU1_07910	COG1902	pentaerythritol trinitrate reductase activity
ASU1_07915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU1_07920	COG2171	N-acyltransferase activity
ASU1_07925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASU1_07935	COG0511	ligase activity, forming carbon-carbon bonds
ASU1_07940	COG0439	Biotin carboxylase
ASU1_07945	COG1763	Mo-molybdopterin cofactor biosynthetic process
ASU1_07950	COG3084	Protein conserved in bacteria
ASU1_07955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASU1_07960	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASU1_07965	COG0742	ribosomal rna small subunit methyltransferase
ASU1_07970	COG1876	peptidase activity
ASU1_07980	COG1393	Belongs to the ArsC family
ASU1_07990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASU1_08010	COG0564	pseudouridine synthase activity
ASU1_08015	COG0668	transmembrane transport
ASU1_08020	COG0439	Biotin carboxylase
ASU1_08035	COG2116	formate transmembrane transporter activity
ASU1_08040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASU1_08060	COG0730	response to heat
ASU1_08080	COG0180	Tryptophanyl-tRNA synthetase
ASU1_08090	COG3120	sequence-specific DNA binding
ASU1_08095	COG1067	ATP-dependent peptidase activity
ASU1_08100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASU1_08110	COG4795	General secretion pathway protein
ASU1_08125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ASU1_08140	COG0443	Heat shock 70 kDa protein
ASU1_08145	COG1070	Carbohydrate kinase
ASU1_08150	COG2115	Belongs to the xylose isomerase family
ASU1_08155	COG4213	ABC transporter substrate-binding protein
ASU1_08160	COG1129	ABC transporter
ASU1_08165	COG4214	carbohydrate transport
ASU1_08170	COG2211	Major facilitator Superfamily
ASU1_08175	COG3507	Belongs to the glycosyl hydrolase 43 family
ASU1_08180	COG1609	Transcriptional regulator
ASU1_08180	COG2207	Transcriptional regulator
ASU1_08185	COG3590	peptidase
ASU1_08205	COG1216	Glycosyl transferase, family 2
ASU1_08205	COG1442	glycosyl transferase family 8
ASU1_08215	COG3338	carbonate dehydratase activity
ASU1_08220	COG3161	chorismate lyase activity
ASU1_08225	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASU1_08230	COG1522	sequence-specific DNA binding
ASU1_08235	COG2502	aspartate--ammonia ligase
ASU1_08245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ASU1_08250	COG1595	DNA-templated transcription, initiation
ASU1_08260	COG0442	prolyl-tRNA aminoacylation
ASU1_08265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASU1_08270	COG2190	(PTS) system
ASU1_08270	COG1263	PTS System
ASU1_08270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASU1_08285	COG2723	6-phospho-beta-galactosidase activity
ASU1_08290	COG3711	transcriptional antiterminator
ASU1_08310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASU1_08315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ASU1_08320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASU1_08325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASU1_08330	COG0254	rRNA binding
ASU1_08335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASU1_08340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASU1_08345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASU1_08350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASU1_08355	COG0470	DNA polymerase III
ASU1_08365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASU1_08380	COG0084	hydrolase, TatD family'
ASU1_08390	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASU1_08395	COG1215	transferase activity, transferring glycosyl groups
ASU1_08400	COG2832	Protein of unknown function (DUF454)
ASU1_08430	COG4804	nuclease activity
ASU1_08470	COG3794	PFAM blue (type 1) copper domain protein
ASU1_08480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU1_08490	COG2850	peptidyl-arginine hydroxylation
ASU1_08495	COG0335	large ribosomal subunit rRNA binding
ASU1_08500	COG0336	Belongs to the RNA methyltransferase TrmD family
ASU1_08505	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASU1_08510	COG0228	four-way junction DNA binding
ASU1_08520	COG0202	RNA polymerase activity
ASU1_08525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASU1_08530	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASU1_08535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASU1_08545	COG0201	protein transport
ASU1_08550	COG0200	Binds to the 23S rRNA
ASU1_08555	COG1841	ribosomal large subunit assembly
ASU1_08560	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASU1_08565	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASU1_08570	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASU1_08575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASU1_08580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASU1_08585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASU1_08590	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASU1_08600	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASU1_08605	COG0255	Belongs to the universal ribosomal protein uL29 family
ASU1_08610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASU1_08615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASU1_08620	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASU1_08625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASU1_08630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASU1_08635	COG0089	rRNA binding
ASU1_08640	COG0088	Forms part of the polypeptide exit tunnel
ASU1_08645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASU1_08650	COG0051	transcription antitermination factor activity, RNA binding
ASU1_08655	COG3070	regulator of competence-specific genes
ASU1_08660	COG0268	Binds directly to 16S ribosomal RNA
ASU1_08665	COG0728	peptidoglycan biosynthetic process
ASU1_08680	COG3276	selenocysteine insertion sequence binding
ASU1_08685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASU1_08690	COG0569	domain protein
ASU1_08700	COG2264	protein methyltransferase activity
ASU1_08720	COG0037	tRNA processing
ASU1_08725	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASU1_08730	COG0204	Acyl-transferase
ASU1_08740	COG0825	malonyl-CoA metabolic process
ASU1_08755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASU1_08760	COG1072	(Pantothenic acid kinase))
ASU1_08765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASU1_08780	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASU1_08790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASU1_08800	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASU1_08825	COG0778	Nitroreductase
ASU1_08830	COG1064	alcohol dehydrogenase
ASU1_08860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASU1_08860	COG0475	glutathione-regulated potassium exporter activity
ASU1_08870	COG1879	ABC-type sugar transport system periplasmic component
ASU1_08880	COG4211	Belongs to the binding-protein-dependent transport system permease family
ASU1_08885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASU1_08900	COG0656	L-ascorbic acid biosynthetic process
ASU1_08905	COG2272	Belongs to the type-B carboxylesterase lipase family
ASU1_08915	COG0673	inositol 2-dehydrogenase activity
ASU1_08940	COG0702	epimerase
ASU1_08960	COG2814	Major facilitator Superfamily
ASU1_08970	COG1304	FMN binding
ASU1_08975	COG0579	oxidoreductase
ASU1_08995	COG1289	transmembrane transporter activity
ASU1_09000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASU1_09010	COG2271	Major facilitator Superfamily
ASU1_09050	COG4206	TonB-dependent receptor
ASU1_09050	COG1629	transport
ASU1_09055	COG4558	Periplasmic binding protein
ASU1_09060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU1_09065	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASU1_09070	COG3477	response to acidic pH
ASU1_09085	COG1126	abc transporter atp-binding protein
ASU1_09090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASU1_09110	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ASU1_09135	COG3623	hexulose-6-phosphate isomerase
ASU1_09140	COG0235	Class ii aldolase
ASU1_09145	COG0425	Belongs to the sulfur carrier protein TusA family
ASU1_09150	COG2391	methyltransferase activity
ASU1_09155	COG0545	Peptidyl-prolyl cis-trans isomerase
ASU1_09165	COG3681	Belongs to the UPF0597 family
ASU1_09190	COG0783	Belongs to the Dps family
ASU1_09195	COG0840	transmembrane signaling receptor activity
ASU1_09200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASU1_09205	COG4989	oxidoreductase activity
ASU1_09215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASU1_09220	COG0321	lipoyl(octanoyl) transferase activity
ASU1_09225	COG2921	Belongs to the UPF0250 family
ASU1_09230	COG1686	Belongs to the peptidase S11 family
ASU1_09235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASU1_09240	COG0772	Belongs to the SEDS family
ASU1_09245	COG0768	penicillin binding
ASU1_09250	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASU1_09255	COG0799	negative regulation of ribosome biogenesis
ASU1_09260	COG2944	sequence-specific DNA binding
ASU1_09265	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASU1_09275	COG1126	abc transporter atp-binding protein
ASU1_09280	COG0765	amino acid transport
ASU1_09285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASU1_09295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASU1_09300	COG1879	ABC-type sugar transport system periplasmic component
ASU1_09305	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASU1_09315	COG1869	D-ribose catabolic process
ASU1_09325	COG1609	Transcriptional regulator
ASU1_09330	COG3265	gluconokinase activity
ASU1_09335	COG2610	gluconate transmembrane transporter activity
ASU1_09340	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU1_09340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASU1_09345	COG3715	PTS system
ASU1_09350	COG3716	PTS system mannose fructose sorbose family IID component
ASU1_09360	COG0561	phosphatase activity
ASU1_09365	COG0445	tRNA wobble uridine modification
ASU1_09370	COG0357	Ribosomal RNA small subunit methyltransferase G
ASU1_09395	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASU1_09400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASU1_09405	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASU1_09410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASU1_09420	COG1442	glycosyl transferase family 8
ASU1_09425	COG2168	tRNA wobble position uridine thiolation
ASU1_09435	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASU1_09440	COG2964	Protein conserved in bacteria
ASU1_09445	COG0545	Peptidyl-prolyl cis-trans isomerase
ASU1_09450	COG2900	Belongs to the SlyX family
ASU1_09455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASU1_09460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASU1_09465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASU1_09470	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ASU1_09480	COG1349	DNA-binding transcription factor activity
ASU1_09485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASU1_09490	COG0490	domain, Protein
ASU1_09490	COG0471	metal ion transport
ASU1_09495	COG0471	metal ion transport
ASU1_09495	COG0490	domain, Protein
ASU1_09495	COG0471	metal ion transport
ASU1_09495	COG0490	domain, Protein
ASU1_09505	COG0583	DNA-binding transcription factor activity
ASU1_09510	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ASU1_09515	COG0310	cobalt ion transport
ASU1_09520	COG0310	cobalt ion transport
ASU1_09525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ASU1_09530	COG1122	ATPase activity
ASU1_09540	COG0831	urea catabolic process
ASU1_09580	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASU1_09585	COG0829	nickel cation binding
ASU1_09600	COG3691	Protein conserved in bacteria
ASU1_09610	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ASU1_09615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASU1_09625	COG0758	DNA mediated transformation
ASU1_09630	COG1297	OPT oligopeptide transporter protein
ASU1_09645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASU1_09655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASU1_09660	COG0081	regulation of translation
ASU1_09670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASU1_09680	COG1028	Short-chain dehydrogenase reductase Sdr
ASU1_09685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASU1_09695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASU1_09715	COG1943	Transposase
ASU1_09720	COG1131	(ABC) transporter
ASU1_09725	COG0842	Transport permease protein
ASU1_09770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASU1_09820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASU1_09825	COG0222	ribosome binding
ASU1_09845	COG0737	Belongs to the 5'-nucleotidase family
ASU1_09850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASU1_09855	COG0606	chelatase, subunit chli
ASU1_09860	COG2267	carboxylic ester hydrolase activity
ASU1_09865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ASU1_09875	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ASU1_09885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASU1_09890	COG0363	glucosamine-6-phosphate deaminase activity
ASU1_09895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASU1_09910	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ASU1_09915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASU1_09920	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASU1_09930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASU1_09935	COG2244	polysaccharide biosynthetic process
ASU1_09940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASU1_09945	COG1151	hydroxylamine reductase activity
ASU1_09960	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ASU1_09965	COG4974	Belongs to the 'phage' integrase family
ASU1_09975	COG1943	Transposase
ASU1_09980	COG2885	chlorophyll binding
ASU1_09980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ASU1_09990	COG0247	lactate metabolic process
ASU1_09990	COG0277	FAD linked oxidase domain protein
ASU1_09995	COG2050	protein possibly involved in aromatic compounds catabolism
ASU1_10010	COG0583	DNA-binding transcription factor activity
ASU1_10025	COG0716	FMN binding
ASU1_10050	COG4771	TonB-dependent receptor
ASU1_10050	COG1629	transport
ASU1_10075	COG2431	L-lysine efflux transmembrane transporter activity
ASU1_10085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASU1_10090	COG3545	Serine hydrolase
ASU1_10105	COG0625	glutathione transferase activity
ASU1_10110	COG0019	diaminopimelate decarboxylase activity
ASU1_10145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASU1_10145	COG1215	transferase activity, transferring glycosyl groups
ASU1_10175	COG1119	ATPase activity
ASU1_10190	COG1739	Uncharacterized protein family UPF0029
ASU1_10195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASU1_10205	COG1970	mechanosensitive ion channel activity
ASU1_10220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASU1_10230	COG0346	lactoylglutathione lyase activity
ASU1_10235	COG1194	a g-specific adenine glycosylase
ASU1_10240	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ASU1_10245	COG0741	lytic transglycosylase activity
ASU1_10250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASU1_10260	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASU1_10270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASU1_10275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASU1_10285	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ASU1_10290	COG1053	succinate dehydrogenase
ASU1_10295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASU1_10300	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASU1_10305	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASU1_10310	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASU1_10315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASU1_10320	COG3062	negative regulation of establishment of protein localization
ASU1_10325	COG0243	molybdopterin cofactor binding
ASU1_10330	COG0437	4 iron, 4 sulfur cluster binding
ASU1_10335	COG0348	domain, Protein
ASU1_10340	COG3043	anaerobic respiration
ASU1_10345	COG3005	denitrification pathway
ASU1_10350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASU1_10360	COG1902	pentaerythritol trinitrate reductase activity
ASU1_10365	COG3691	Protein conserved in bacteria
ASU1_10370	COG0814	amino acid
ASU1_10380	COG2918	glutathione biosynthetic process
ASU1_10380	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASU1_10385	COG0688	phosphatidylethanolamine metabolic process
ASU1_10390	COG1555	photosystem II stabilization
ASU1_10395	COG3266	domain, Protein
ASU1_10395	COG3061	Opacity-associated protein A
ASU1_10405	COG0859	PFAM glycosyl transferase family 9
ASU1_10410	COG0859	PFAM glycosyl transferase family 9
ASU1_10415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASU1_10420	COG0049	tRNA binding
ASU1_10425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASU1_10430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASU1_10435	COG1575	Belongs to the MenA family. Type 1 subfamily
ASU1_10440	COG4804	nuclease activity
ASU1_10445	COG1720	tRNA m6t6A37 methyltransferase activity
ASU1_10455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASU1_10470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASU1_10475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASU1_10480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASU1_10485	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ASU1_10490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASU1_10495	COG1755	Isoprenylcysteine carboxyl methyltransferase
ASU1_10505	COG1530	ribonuclease E activity
ASU1_10535	COG2153	protein acetylation
ASU1_10540	COG2927	DNA polymerase III (CHI subunit)
ASU1_10545	COG1652	LysM domain
ASU1_10550	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASU1_10555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASU1_10560	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASU1_10565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASU1_10570	COG1045	serine acetyltransferase
ASU1_10580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ASU1_10580	COG1215	transferase activity, transferring glycosyl groups
ASU1_10595	COG1442	glycosyl transferase family 8
ASU1_10595	COG1216	Glycosyl transferase, family 2
ASU1_10605	COG1216	Glycosyl transferase, family 2
ASU1_10615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASU1_10620	COG1088	dTDP-glucose 4,6-dehydratase activity
ASU1_10630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASU1_10640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASU1_10645	COG2824	Alkylphosphonate utilization operon protein PhnA
ASU1_10650	COG1858	cytochrome C peroxidase
ASU1_10655	COG1872	DUF167
ASU1_10660	COG0762	integral membrane protein
ASU1_10665	COG3171	Protein conserved in bacteria
ASU1_10670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASU1_10675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASU1_10680	COG0416	fatty acid biosynthetic process
ASU1_10685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASU1_10690	COG1399	metal-binding, possibly nucleic acid-binding protein
ASU1_10695	COG4137	Cytochrome C assembly protein
ASU1_10700	COG4536	flavin adenine dinucleotide binding
ASU1_10705	COG0733	neurotransmitter:sodium symporter activity
ASU1_10715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASU1_10715	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU1_10720	COG3715	PTS system
ASU1_10725	COG3716	PTS system mannose fructose sorbose family IID component
ASU1_10735	COG1482	cell wall glycoprotein biosynthetic process
ASU1_10765	COG1840	ABC-type Fe3 transport system, periplasmic component
ASU1_10785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASU1_10795	COG0557	exoribonuclease II activity
ASU1_10800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASU1_10805	COG1309	transcriptional regulator
ASU1_10810	COG0583	DNA-binding transcription factor activity
ASU1_10815	COG0678	peroxiredoxin activity
ASU1_10815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASU1_10825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASU1_10845	COG3118	belongs to the thioredoxin family
ASU1_10865	COG0625	glutathione transferase activity
ASU1_10885	COG2084	Dehydrogenase
ASU1_10890	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASU1_10900	COG0732	type I restriction modification DNA specificity domain
ASU1_10910	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASU1_10920	COG3630	sodium ion export across plasma membrane
ASU1_10925	COG0471	metal ion transport
ASU1_10930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ASU1_10945	COG1793	dna ligase
ASU1_10955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASU1_10960	COG4133	protoheme IX ABC transporter activity
ASU1_10965	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASU1_10970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASU1_10975	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASU1_10985	COG1138	Cytochrome C-type biogenesis protein
ASU1_10995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASU1_11010	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASU1_11015	COG0792	nuclease activity
ASU1_11020	COG3107	peptidoglycan biosynthetic process
ASU1_11030	COG3101	peptidyl-lysine hydroxylation
ASU1_11035	COG4232	protein-disulfide reductase activity
ASU1_11045	COG3620	sequence-specific DNA binding
ASU1_11060	COG1126	abc transporter atp-binding protein
ASU1_11065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASU1_11070	COG4215	(ABC) transporter
ASU1_11075	COG4160	amino acid transport
ASU1_11085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASU1_11090	COG3099	Belongs to the UPF0263 family
ASU1_11095	COG0742	ribosomal rna small subunit methyltransferase
ASU1_11100	COG0552	protein localization to endoplasmic reticulum
ASU1_11105	COG2884	Cell division ATP-binding protein ftsE
ASU1_11110	COG2177	Part of the ABC transporter FtsEX involved in
ASU1_11135	COG1040	competence protein
ASU1_11140	COG0583	DNA-binding transcription factor activity
ASU1_11145	COG2813	Specifically methylates the guanine in position
ASU1_11155	COG0456	acetyltransferase
ASU1_11160	COG0513	Belongs to the DEAD box helicase family
ASU1_11170	COG0747	negative chemotaxis
ASU1_11180	COG1584	GPR1 FUN34 yaaH family protein
ASU1_11185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASU1_11190	COG1120	ATPase activity
ASU1_11200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU1_11205	COG4774	siderophore transport
ASU1_11215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASU1_11225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASU1_11230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASU1_11250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASU1_11270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASU1_11270	COG0140	phosphoribosyl-ATP diphosphatase activity
ASU1_11275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASU1_11280	COG0024	Methionine aminopeptidase
ASU1_11285	COG0210	DNA helicase
ASU1_11300	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASU1_11305	COG1136	(ABC) transporter
ASU1_11310	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASU1_11315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family