locus-tag	class	description
DLE03_00005	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DLE03_00010	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
DLE03_00015	ENOG4105CAK	Cell division ATP-binding protein ftsE
DLE03_00020	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
DLE03_00070	ENOG4105CHR	reductase
DLE03_00075	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
DLE03_00080	ENOG4105ZIR	glutaredoxin-like protein
DLE03_00090	ENOG4108VEQ	Superoxide dismutase
DLE03_00105	ENOG4105EMN	RNA polymerase sigma factor
DLE03_00110	ENOG4108RAV	Conserved protein
DLE03_00115	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DLE03_00120	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DLE03_00125	ENOG4107TK4	histidinol-phosphate phosphatase
DLE03_00135	ENOG4105VE1	Phosphatidylcholine synthase
DLE03_00150	ENOG4105DJZ	UPF0182 protein
DLE03_00155	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DLE03_00185	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DLE03_00205	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
DLE03_00215	ENOG4105C4R	Atp-dependent dna helicase
DLE03_00220	ENOG4105CI3	gtp-binding protein typa
DLE03_00225	ENOG4105C3G	gtp-binding protein
DLE03_00230	ENOG4105CGY	Dna recombination protein
DLE03_00245	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
DLE03_00250	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DLE03_00255	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DLE03_00260	ENOG4107GFK	fumarate
DLE03_00270	ENOG4108IAB	Phoh family
DLE03_00290	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DLE03_00355	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DLE03_00375	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DLE03_00380	ENOG4105D82	Glutamate dehydrogenase
DLE03_00385	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DLE03_00390	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DLE03_00395	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DLE03_00400	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DLE03_00415	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
DLE03_00420	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DLE03_00425	ENOG4105F8V	Hydrolase, tatD family
DLE03_00430	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DLE03_00460	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
DLE03_00465	ENOG4105C1G	acyl-Coa dehydrogenase
DLE03_00485	ENOG4107R13	MMPL domain protein
DLE03_00510	ENOG4108IXY	short-chain dehydrogenase reductase
DLE03_00515	ENOG4105C1J	atp-dependent rna helicase
DLE03_00525	ENOG4105BZU	Histidine kinase
DLE03_00530	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
DLE03_00540	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
DLE03_00545	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DLE03_00575	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DLE03_00585	ENOG4105CGD	Nad-dependent epimerase dehydratase
DLE03_00595	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
DLE03_00610	ENOG4105CNT	hydrolase family 2
DLE03_00625	ENOG4105C8N	cysteinyl-tRNA synthetase
DLE03_00630	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DLE03_00635	ENOG4108VJ1	Transcriptional regulator (CarD family
DLE03_00645	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DLE03_00655	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DLE03_00665	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
DLE03_00675	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
DLE03_00680	ENOG4105I3K	Ferric uptake regulator, Fur family
DLE03_00685	ENOG4105PKJ	carbohydrate binding
DLE03_00690	ENOG4105KHC	sulfurtransferase
DLE03_00705	ENOG4107NHD	transcriptional regulator
DLE03_00710	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
DLE03_00715	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DLE03_00730	ENOG41090KN	UPF0303 protein
DLE03_00760	ENOG4107QQG	Dehydrogenase
DLE03_00795	ENOG4107QRS	glycosyltransferase group 2 family protein
DLE03_00835	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DLE03_00840	ENOG4105EXC	Acyl-transferase
DLE03_00850	ENOG4105CKK	Glycosyl transferase, family 2
DLE03_00865	ENOG4105FAW	cDP-glucose 4,6-dehydratase
DLE03_00870	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DLE03_00875	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
DLE03_00880	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DLE03_00885	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DLE03_00900	ENOG4107QRG	dna polymerase iii
DLE03_00905	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DLE03_00915	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DLE03_00920	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DLE03_00930	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
DLE03_00935	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
DLE03_00940	ENOG4105EPJ	extracellular solute-binding protein family 1
DLE03_00950	ENOG4105DQR	SNARE associated Golgi
DLE03_00955	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DLE03_00970	ENOG4105KNI	merR family transcriptional Regulator
DLE03_00975	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DLE03_00980	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DLE03_00985	ENOG4105CFG	Acts as a chaperone (By similarity)
DLE03_00990	ENOG4105K7N	UPF0232 protein
DLE03_00995	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DLE03_01000	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DLE03_01005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DLE03_01010	ENOG4107MMV	50S ribosomal protein L34
DLE03_01015	ENOG4108CDF	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
DLE03_01020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DLE03_01025	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DLE03_01035	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
DLE03_01040	ENOG4107QJE	Chromosome Partitioning Protein
DLE03_01050	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DLE03_01055	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DLE03_01060	ENOG4105K63	Thioredoxin
DLE03_01065	ENOG4105C3M	thioredoxin reductase
DLE03_01085	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DLE03_01100	ENOG4105BZ4	penicillin-binding protein
DLE03_01110	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
DLE03_01115	ENOG4107YH6	single-stranded DNA-binding protein
DLE03_01120	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DLE03_01125	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DLE03_01130	ENOG4105D7N	magnesium and cobalt transport protein CorA
DLE03_01135	ENOG4105CDU	Replicative dna helicase
DLE03_01145	ENOG4105CSU	acyl-Coa dehydrogenase
DLE03_01150	ENOG4105DHP	deoxycytidine triphosphate deaminase
DLE03_01155	ENOG4108V0P	LemA family
DLE03_01160	ENOG4105D0M	Protease HtpX homolog
DLE03_01165	ENOG4105BZU	Histidine kinase
DLE03_01170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DLE03_01175	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DLE03_01180	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DLE03_01205	ENOG4107ZXI	Rhomboid family
DLE03_01210	ENOG4105DF6	Fe-S oxidoreductase
DLE03_01220	ENOG4105ZJT	Cell division protein CrgA
DLE03_01250	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DLE03_01255	ENOG410667J	hydrolase
DLE03_01275	ENOG4105E33	succinate dehydrogenase
DLE03_01280	ENOG41082T9	Membrane
DLE03_01285	ENOG41082CG	Protein CrcB homolog
DLE03_01295	ENOG4107T6F	Xaa-Pro aminopeptidase
DLE03_01300	ENOG4105C26	Dehydrogenase
DLE03_01315	ENOG4105CMT	Dihydroxyacetone kinase
DLE03_01325	ENOG4105C2J	ABC transporter
DLE03_01330	ENOG4105CNN	ABC, transporter
DLE03_01335	ENOG4105CNN	ABC, transporter
DLE03_01340	ENOG4105CN9	Peptidase m42 family protein
DLE03_01350	ENOG4105CPQ	Dehydrogenase
DLE03_01360	ENOG4106KE4	Dehydrogenase
DLE03_01365	ENOG4106P19	photosystem i assembly btpa
DLE03_01370	ENOG4105N2W	Transcriptional regulator
DLE03_01410	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DLE03_01435	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DLE03_01440	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DLE03_01445	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
DLE03_01455	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
DLE03_01465	ENOG4105C5H	ABC transporter
DLE03_01485	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DLE03_01495	ENOG4108Z6B	deaminase
DLE03_01500	ENOG4105C0X	amino acid
DLE03_01545	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
DLE03_01550	ENOG4105CFH	Aspartokinase
DLE03_01565	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
DLE03_01575	ENOG4105KTH	gatB Yqey
DLE03_01605	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DLE03_01610	ENOG4107RCW	fructose-bisphosphate aldolase
DLE03_01615	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DLE03_01620	ENOG4105C12	Phosphoribosylglycinamide synthetase
DLE03_01625	ENOG4105C83	adenylosuccinate lyase
DLE03_01630	ENOG4105C8V	SAICAR synthetase
DLE03_01635	ENOG410839H	phosphoribosylformylglycinamidine synthase
DLE03_01640	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
DLE03_01645	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
DLE03_01685	ENOG4105ESV	Glycosyl transferase, family 4
DLE03_01720	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DLE03_01725	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DLE03_01740	ENOG4105D9G	High-affinity
DLE03_01765	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
DLE03_01775	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DLE03_01800	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DLE03_01815	ENOG4105EUJ	GTP cyclohydrolase i
DLE03_01820	ENOG4105EEI	dihydropteroate synthase
DLE03_01830	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DLE03_01835	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DLE03_01840	ENOG4108IYU	L-aspartate oxidase
DLE03_01850	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
DLE03_01855	ENOG4105CRK	lysyL-tRNA synthetase
DLE03_01870	ENOG4105CEN	a g-specific adenine glycosylase
DLE03_01875	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
DLE03_01880	ENOG4108JWX	
DLE03_01905	ENOG4105CFI	type iii restriction protein res subunit
DLE03_01925	ENOG4108RH7	phosphoglycerate mutase
DLE03_01930	ENOG4107QX9	Thiol disulfide interChange protein
DLE03_01935	ENOG4107QIV	Cytochrome c biogenesis protein
DLE03_01940	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
DLE03_01945	ENOG4105CRE	cytochrome C
DLE03_01970	ENOG4108IPT	Naphthoate synthase
DLE03_01975	ENOG4107TCW	O-succinylbenzoate synthase
DLE03_01980	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
DLE03_01985	ENOG4105E4F	Isochorismate synthase
DLE03_01990	ENOG4107ZYJ	bioY protein
DLE03_01995	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DLE03_02005	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE03_02010	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DLE03_02015	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE03_02025	ENOG4107QIZ	NADH dehydrogenase
DLE03_02030	ENOG4108IEH	NADH dehydrogenase subunit g
DLE03_02035	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
DLE03_02040	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE03_02045	ENOG41087XN	oxidoreductase
DLE03_02050	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE03_02065	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE03_02080	ENOG4108VPT	UPF0234 protein
DLE03_02090	ENOG4105CNN	ABC, transporter
DLE03_02130	ENOG4105DIA	mandelate racemase muconate lactonizing
DLE03_02140	ENOG4105E0X	reductase
DLE03_02160	ENOG4105K4P	CoA-binding domain protein
DLE03_02170	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
DLE03_02185	ENOG4105WDJ	50S ribosomal protein L33
DLE03_02190	ENOG410900P	UPF0336 protein
DLE03_02200	ENOG4105C8N	cysteinyl-tRNA synthetase
DLE03_02205	ENOG4107R4N	Cell wall formation (By similarity)
DLE03_02230	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DLE03_02235	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DLE03_02240	ENOG4108VZM	50s ribosomal protein L10
DLE03_02245	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DLE03_02250	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DLE03_02255	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DLE03_02265	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
DLE03_02270	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DLE03_02275	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DLE03_02280	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DLE03_02285	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DLE03_02290	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DLE03_02295	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DLE03_02300	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DLE03_02310	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DLE03_02315	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DLE03_02320	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DLE03_02325	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DLE03_02330	ENOG41082SA	50s ribosomal protein l29
DLE03_02335	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DLE03_02340	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DLE03_02345	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DLE03_02350	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DLE03_02355	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DLE03_02360	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DLE03_02365	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DLE03_02370	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DLE03_02375	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DLE03_02380	ENOG410849U	50S ribosomal protein L30
DLE03_02395	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DLE03_02400	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DLE03_02425	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DLE03_02430	ENOG41067V7	50S ribosomal protein L36
DLE03_02435	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DLE03_02440	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DLE03_02445	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DLE03_02450	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DLE03_02455	ENOG4108ZT0	50S ribosomal protein l17
DLE03_02460	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
DLE03_02465	ENOG4105C5H	ABC transporter
DLE03_02470	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DLE03_02475	ENOG4108UJD	30S ribosomal protein S9
DLE03_02480	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DLE03_02485	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DLE03_02495	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DLE03_02500	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DLE03_02505	ENOG4105C0Z	ABC transporter
DLE03_02510	ENOG4108IV0	ABC, transporter
DLE03_02515	ENOG4105C32	Amino acid ABC transporter (Permease)
DLE03_02520	ENOG4105C32	Amino acid ABC transporter (Permease)
DLE03_02535	ENOG4108097	ATP-binding protein
DLE03_02550	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DLE03_02555	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
DLE03_02565	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DLE03_02580	ENOG4107QVP	Dehydrogenase
DLE03_02585	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DLE03_02590	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
DLE03_02595	ENOG4106QSE	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
DLE03_02605	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DLE03_02630	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
DLE03_02640	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DLE03_02665	ENOG4105C31	Tryptophanyl-tRNA synthetase
DLE03_02670	ENOG4107TFB	basic membrane
DLE03_02675	ENOG4105DIH	basic membrane
DLE03_02680	ENOG4108JQ9	ABC transporter
DLE03_02685	ENOG4105UIB	(ABC) transporter
DLE03_02705	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DLE03_02710	ENOG4105C26	Dehydrogenase
DLE03_02715	ENOG4105C26	Dehydrogenase
DLE03_02725	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
DLE03_02735	ENOG4108JIK	carboxylase
DLE03_02740	ENOG4107WR6	Maf-like protein
DLE03_02750	ENOG4105D8K	carboxyl transferase
DLE03_02765	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DLE03_02770	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DLE03_02775	ENOG4108KGH	TRANSCRIPTIONal
DLE03_02790	ENOG4105EY8	ABC transporter
DLE03_02800	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
DLE03_02805	ENOG4108URH	decarboxylase
DLE03_02825	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DLE03_02830	ENOG4107ZBN	O-methyltransferase
DLE03_02840	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
DLE03_02845	ENOG4105D1F	ATP-binding protein
DLE03_02855	ENOG4105CJW	magnesium transporter
DLE03_02870	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
DLE03_02875	ENOG4105C1J	atp-dependent rna helicase
DLE03_02895	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
DLE03_02905	ENOG4105C8N	cysteinyl-tRNA synthetase
DLE03_02910	ENOG4108Z4U	Ferredoxin
DLE03_02920	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
DLE03_02925	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DLE03_02930	ENOG4107RGC	Glycosyl transferase, family 2
DLE03_02945	ENOG4107QKV	phosphomannomutase
DLE03_02950	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
DLE03_02955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DLE03_02960	ENOG4105BZU	Histidine kinase
DLE03_02965	ENOG4105MJ2	Competence protein
DLE03_02970	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DLE03_03010	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DLE03_03020	ENOG4105C87	Aminotransferase class I and II
DLE03_03045	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DLE03_03050	ENOG4105BZU	Histidine kinase
DLE03_03060	ENOG4105CDH	Citrulline--aspartate ligase
DLE03_03065	ENOG4108V1T	peptidylprolyl cis-trans isomerase
DLE03_03070	ENOG4105CG3	alpha amylase, catalytic region
DLE03_03075	ENOG4105EN6	Membrane
DLE03_03095	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DLE03_03110	ENOG4105F0N	pyrophosphate phospho-hydrolase
DLE03_03120	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
DLE03_03135	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DLE03_03160	ENOG4105JHE	Major Facilitator Superfamily
DLE03_03170	ENOG4105D8X	mechanosensitive ion channel
DLE03_03190	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DLE03_03195	ENOG4108YZG	isomerase
DLE03_03220	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DLE03_03225	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DLE03_03230	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DLE03_03240	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DLE03_03245	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DLE03_03250	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DLE03_03260	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
DLE03_03265	ENOG4105DFF	Rod shape-determining protein mreb
DLE03_03285	ENOG4105CNI	cell division protein FtsW
DLE03_03290	ENOG4105C03	ribonuclease
DLE03_03295	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DLE03_03300	ENOG4105K46	50S ribosomal protein l27
DLE03_03305	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DLE03_03310	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DLE03_03315	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DLE03_03320	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DLE03_03325	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DLE03_03330	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DLE03_03340	ENOG4105C01	Dihydroxy-acid dehydratase
DLE03_03350	ENOG4108ZP8	Acetolactate synthase small subunit
DLE03_03355	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DLE03_03365	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DLE03_03370	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DLE03_03375	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DLE03_03390	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DLE03_03395	ENOG4105CE9	30S ribosomal protein S2
DLE03_03400	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
DLE03_03405	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DLE03_03410	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DLE03_03420	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DLE03_03430	ENOG4105C26	Dehydrogenase
DLE03_03440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DLE03_03445	ENOG4105F38	ABC transporter, permease
DLE03_03460	ENOG4105DZP	Membrane-associated zinc metalloprotease
DLE03_03465	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
DLE03_03470	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DLE03_03475	ENOG4105EJ9	Membrane
DLE03_03480	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
DLE03_03490	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DLE03_03490	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DLE03_03495	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DLE03_03500	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DLE03_03510	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DLE03_03515	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DLE03_03520	ENOG4105C1V	Peptidase, M16
DLE03_03525	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DLE03_03550	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DLE03_03555	ENOG4105CN5	Metallo-Beta-Lactamase
DLE03_03560	ENOG4107QZI	cell division protein FtsK
DLE03_03570	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
DLE03_03580	ENOG4105CEV	competence damage-inducible protein
DLE03_03585	ENOG4105WBV	Transcriptional regulator
DLE03_03615	ENOG4105KC9	Modulates RecA activity (By similarity)
DLE03_03625	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DLE03_03630	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DLE03_03635	ENOG4105K70	DNA-binding protein
DLE03_03645	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DLE03_03650	ENOG4105CPF	Cell wall formation (By similarity)
DLE03_03665	ENOG4105VB9	50S ribosomal protein l28
DLE03_03675	ENOG4106H78	methyltransferase
DLE03_03680	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DLE03_03695	ENOG41084BZ	50S ribosomal protein L32
DLE03_03700	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DLE03_03710	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DLE03_03725	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
DLE03_03730	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DLE03_03735	ENOG4105K5M	30s ribosomal protein S16
DLE03_03740	ENOG41082KU	UPF0109 protein
DLE03_03745	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DLE03_03750	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DLE03_03760	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DLE03_03765	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DLE03_03770	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
DLE03_03775	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DLE03_03795	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DLE03_03810	ENOG4107VEG	TrkA-N domain protein
DLE03_03815	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DLE03_03820	ENOG4107QM5	aconitate hydratase
DLE03_03825	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DLE03_03830	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DLE03_03835	ENOG4105CHU	acetyl-coa acetyltransferase
DLE03_03865	ENOG4107SN7	NLP P60 protein
DLE03_03870	ENOG4105JNK	Glycosyl transferase (Group 1
DLE03_03895	ENOG4105DKQ	ROK family
DLE03_03915	ENOG4105N14	lysine exporter protein LysE YggA
DLE03_03925	ENOG4105CZA	synthase
DLE03_03930	ENOG41060WC	Enoyl-CoA hydratase
DLE03_03940	ENOG4105CDA	abc transporter atp-binding protein
DLE03_03945	ENOG4105E5Q	amino acid AbC transporter
DLE03_03950	ENOG4105CT1	(ABC) transporter
DLE03_03960	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DLE03_03965	ENOG4105C5F	glutamine synthetase
DLE03_03985	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DLE03_03990	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DLE03_03995	ENOG4105EYF	MMPL domain protein
DLE03_04000	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
DLE03_04005	ENOG4105CVN	desaturase
DLE03_04010	ENOG4105ECP	epimerase
DLE03_04025	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DLE03_04030	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
DLE03_04040	ENOG4108JJB	ABC transporter
DLE03_04045	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
DLE03_04055	ENOG4105CPC	Aldo Keto reductase
DLE03_04065	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
DLE03_04075	ENOG4107T4Z	adenosine kinase
DLE03_04085	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
DLE03_04090	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DLE03_04095	ENOG4105MCD	Part of cytochrome c oxidase, its function is
DLE03_04105	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DLE03_04110	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DLE03_04115	ENOG4107EUI	c reductase, iron-sulfur
DLE03_04125	ENOG4105CCU	oxidase (Subunit III)
DLE03_04135	ENOG4108I0Q	anthranilate phosphoribosyltransferase
DLE03_04150	ENOG4105C84	Histidine ammonia-lyase
DLE03_04155	ENOG4105CI2	imidazolone-5-propionate hydrolase
DLE03_04160	ENOG4105CGP	Urocanate hydratase
DLE03_04175	ENOG4105K59	histidine triad (HIT) protein
DLE03_04195	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DLE03_04200	ENOG4105CTU	Proline racemase
DLE03_04210	ENOG4107Y9U	Membrane
DLE03_04240	ENOG4105CRQ	synthase (Component I)
DLE03_04250	ENOG4105C22	threonyL-tRNA synthetase
DLE03_04270	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
DLE03_04275	ENOG4105E2K	Glycosyl transferase (Group 1
DLE03_04295	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
DLE03_04300	ENOG4105CDY	transcriptional regulatory protein
DLE03_04305	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
DLE03_04310	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DLE03_04315	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DLE03_04320	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DLE03_04325	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DLE03_04330	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DLE03_04335	ENOG4105C99	atpase involved in dna repair
DLE03_04340	ENOG4105C5X	domain protein
DLE03_04345	ENOG4105CUT	histidyl-tRNA synthetase
DLE03_04350	ENOG4105C9M	aspartyl-trna synthetase
DLE03_04360	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DLE03_04365	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DLE03_04375	ENOG4105E2X	shikimate dehydrogenase
DLE03_04385	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DLE03_04390	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DLE03_04395	ENOG4105D49	3-dehydroquinate synthase
DLE03_04400	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
DLE03_04405	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DLE03_04410	ENOG410803B	Involved in the transcription termination process (By similarity)
DLE03_04420	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
DLE03_04425	ENOG4105CXT	aspartate transcarbamylase
DLE03_04430	ENOG4105CD3	dihydroorotase
DLE03_04435	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DLE03_04440	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DLE03_04445	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
DLE03_04450	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DLE03_04455	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
DLE03_04460	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
DLE03_04465	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
DLE03_04475	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
DLE03_04485	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DLE03_04490	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DLE03_04500	ENOG4105DJV	ribulose-phosphate 3-epimerase
DLE03_04505	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
DLE03_04510	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DLE03_04515	ENOG4105EAC	phosphoserine phosphatase
DLE03_04520	ENOG4105DKW	ABC transporter
DLE03_04525	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DLE03_04530	ENOG4105C7N	Xanthine uracil vitamin C permease
DLE03_04535	ENOG4108VW9	Membrane
DLE03_04540	ENOG4108UQV	Membrane
DLE03_04545	ENOG4105DQ4	alcohol dehydrogenase
DLE03_04550	ENOG4107W53	thymidine kinase
DLE03_04555	ENOG4105EXC	Acyl-transferase
DLE03_04560	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DLE03_04570	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DLE03_04575	ENOG4108FN7	Aldo keto reductase
DLE03_04595	ENOG4105C8N	cysteinyl-tRNA synthetase
DLE03_04605	ENOG4105C3R	Methionine synthase
DLE03_04620	ENOG4108FFZ	Transcriptional regulator
DLE03_04635	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DLE03_04650	ENOG4105HFS	5'-3' exonuclease
DLE03_04655	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
DLE03_04660	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DLE03_04690	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
DLE03_04695	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DLE03_04715	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
DLE03_04720	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
DLE03_04740	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DLE03_04745	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DLE03_04750	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DLE03_04790	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DLE03_04795	ENOG4105CH7	arginosuccinase
DLE03_04800	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
DLE03_04805	ENOG4105C8Y	Acetylornithine aminotransferase
DLE03_04815	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
DLE03_04820	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DLE03_04825	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DLE03_04830	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
DLE03_04835	ENOG4108RWN	rrna methyltransferase
DLE03_04840	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DLE03_04850	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
DLE03_04855	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
DLE03_04875	ENOG4105BZ1	(ABC) transporter
DLE03_04880	ENOG4105VG1	fes assembly suf system protein
DLE03_04885	ENOG4108UNV	SUF system FeS assembly protein, NifU family
DLE03_04890	ENOG4105C9B	Cysteine desulfurase
DLE03_04895	ENOG4105C3K	feS assembly ATPase SufC
DLE03_04905	ENOG4105JRK	feS assembly protein SufD
DLE03_04920	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
DLE03_04925	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DLE03_04930	ENOG4105C89	phosphohexose isomerase
DLE03_04945	ENOG4105CP7	Triose-phosphate isomerase
DLE03_04950	ENOG4105BZA	Phosphoglycerate kinase
DLE03_04955	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DLE03_04960	ENOG4105CIE	May be required for sporulation (By similarity)
DLE03_04970	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
DLE03_04975	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DLE03_04980	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DLE03_04985	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DLE03_04990	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
DLE03_04995	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DLE03_05010	ENOG4105KA0	thioesterase Superfamily protein
DLE03_05015	ENOG4108IV0	ABC, transporter
DLE03_05020	ENOG4105C0Z	ABC transporter
DLE03_05025	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DLE03_05030	ENOG4105C32	Amino acid ABC transporter (Permease)
DLE03_05060	ENOG4105CBC	glutamate synthase
DLE03_05070	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
DLE03_05085	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DLE03_05090	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DLE03_05095	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DLE03_05100	ENOG4105CRQ	synthase (Component I)
DLE03_05105	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DLE03_05110	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DLE03_05115	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
DLE03_05125	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DLE03_05130	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DLE03_05135	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DLE03_05150	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
DLE03_05160	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DLE03_05170	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
DLE03_05175	ENOG4105DFA	alanine racemase domain protein
DLE03_05180	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DLE03_05185	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DLE03_05195	ENOG4105DFU	Cell wall formation (By similarity)
DLE03_05200	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DLE03_05210	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DLE03_05215	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DLE03_05225	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DLE03_05230	ENOG4105CJN	penicillin-binding protein
DLE03_05240	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DLE03_05245	ENOG4108V6E	Cell division protein mraZ
DLE03_05260	ENOG4105C0B	DNA polymerase III (alpha subunit)
DLE03_05280	ENOG4105DJB	Major Facilitator Superfamily
DLE03_05310	ENOG4105CKK	Glycosyl transferase, family 2
DLE03_05320	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
DLE03_05360	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
DLE03_05375	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DLE03_05380	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
DLE03_05385	ENOG4105CTQ	phosphohexokinase
DLE03_05395	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
DLE03_05405	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DLE03_05410	ENOG4107QPH	glycogen) synthase
DLE03_05420	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DLE03_05425	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DLE03_05440	ENOG41080R2	UPF0102 protein
DLE03_05445	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DLE03_05450	ENOG4107QYR	Signal peptidase i
DLE03_05455	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DLE03_05475	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
DLE03_05480	ENOG4108RVA	ribokinase
DLE03_05485	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DLE03_05495	ENOG4105C5H	ABC transporter
DLE03_05515	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DLE03_05520	ENOG4105DWV	Homoserine O-trans-acetylase
DLE03_05540	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
DLE03_05545	ENOG4105EHG	Permease protein
DLE03_05550	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
DLE03_05575	ENOG4105FDR	Membrane
DLE03_05580	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DLE03_05585	ENOG4105C26	Dehydrogenase
DLE03_05590	ENOG4105DTQ	mandelate racemase muconate lactonizing
DLE03_05605	ENOG4105E90	ABC transporter
DLE03_05610	ENOG4108IJ8	ABC transporter
DLE03_05615	ENOG4105E90	ABC transporter
DLE03_05630	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
DLE03_05640	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
DLE03_05650	ENOG4108R6K	riboflavin synthase, subunit alpha
DLE03_05660	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DLE03_05665	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DLE03_05670	ENOG41067Z0	domain protein
DLE03_05675	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DLE03_05690	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
DLE03_05705	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DLE03_05710	ENOG4105CHR	reductase
DLE03_05800	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DLE03_05880	ENOG4105CYW	agmatinase
DLE03_05900	ENOG4105ERH	Fumarylacetoacetate hydrolase
DLE03_05905	ENOG4105BZW	Glycerate kinase
DLE03_05910	ENOG4108IQI	permease
DLE03_05920	ENOG4105CQB	FAD linked oxidase domain protein
DLE03_05935	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
DLE03_05940	ENOG4105ERH	Fumarylacetoacetate hydrolase
DLE03_05965	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DLE03_05970	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DLE03_05975	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
DLE03_05985	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DLE03_05990	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
DLE03_06010	ENOG4105C8T	Leucyl-tRNA synthetase
DLE03_06020	ENOG4107TB6	phosphoglycerate mutase
DLE03_06025	ENOG4107ZFZ	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DLE03_06030	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DLE03_06035	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DLE03_06040	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DLE03_06050	ENOG4105C10	Electron transfer flavoprotein
DLE03_06060	ENOG4105BZF	Glycosyl transferase (Group 1
DLE03_06065	ENOG4108MJN	Glycosyl Transferase
DLE03_06085	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DLE03_06090	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DLE03_06120	ENOG4105VEQ	Cold shock protein
DLE03_06145	ENOG4105DCF	alanine dehydrogenase
DLE03_06160	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
DLE03_06185	ENOG4105BZU	Histidine kinase
DLE03_06190	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DLE03_06200	ENOG4108WQH	regulatoR
DLE03_06215	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
DLE03_06220	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DLE03_06230	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
DLE03_06240	ENOG4105C0H	protease
DLE03_06245	ENOG41081YG	arsenite oxidase, small subunit
DLE03_06260	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
DLE03_06275	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
DLE03_06290	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DLE03_06295	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
DLE03_06300	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DLE03_06320	ENOG4105C4K	Nad synthetase
DLE03_06325	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DLE03_06345	ENOG4105C9K	Endothelin-converting enzyme 1
DLE03_06355	ENOG4108JQ7	(ABC) transporter
DLE03_06360	ENOG4105C3U	ABC transporter
DLE03_06370	ENOG4108J59	Extracellular solute-binding protein, family 5
DLE03_06375	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DLE03_06400	ENOG4108J5G	6-phosphogluconate dehydrogenase
DLE03_06405	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
DLE03_06415	ENOG41061ZR	Transcriptional regulator
DLE03_06425	ENOG4105CXN	decarboxylase
DLE03_06455	ENOG4105DU1	integral membrane protein, terc
DLE03_06460	ENOG4105C26	Dehydrogenase
DLE03_06470	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
DLE03_06475	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
DLE03_06495	ENOG4105T38	integral membrane protein
DLE03_06525	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
DLE03_06550	ENOG4105CPQ	Dehydrogenase
DLE03_06555	ENOG4105DEI	Mannitol dehydrogenase
DLE03_06620	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DLE03_06625	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
DLE03_06630	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
DLE03_06660	ENOG4105C26	Dehydrogenase
DLE03_06670	ENOG4105CJ1	ABC, transporter
DLE03_06705	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DLE03_06710	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DLE03_06715	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DLE03_06720	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DLE03_06725	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DLE03_06730	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
DLE03_06735	ENOG4106DE0	ATP synthase
DLE03_06740	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
DLE03_06760	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DLE03_06770	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DLE03_06775	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DLE03_06780	ENOG4105VFB	Binds the 23S rRNA (By similarity)
DLE03_06795	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DLE03_06800	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
DLE03_06805	ENOG4105D6E	homoserine dehydrogenase
DLE03_06815	ENOG4105C75	arginyL-tRNA synthetase
DLE03_06820	ENOG4105DFW	ABC transporter
DLE03_06825	ENOG4105C2J	ABC transporter
DLE03_06830	ENOG4108HWW	ABC transporter
DLE03_06885	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DLE03_06890	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DLE03_06895	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
DLE03_06920	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
DLE03_06940	ENOG4105C72	UPF0176 protein
DLE03_06950	ENOG4105EUB	pirin domain protein
DLE03_06960	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DLE03_06965	ENOG4105W8H	transhydrogenase (subunit alpha
DLE03_06970	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DLE03_06975	ENOG4105DBV	ornithine carbamoyltransferase