locus-tag	class	description
DLE04_00005	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DLE04_00010	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
DLE04_00015	ENOG4105CAK	Cell division ATP-binding protein ftsE
DLE04_00020	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
DLE04_00060	ENOG4105CHR	reductase
DLE04_00065	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
DLE04_00075	ENOG4108VEQ	Superoxide dismutase
DLE04_00090	ENOG4105EMN	RNA polymerase sigma factor
DLE04_00095	ENOG4108RAV	Conserved protein
DLE04_00100	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DLE04_00105	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DLE04_00110	ENOG4107TK4	histidinol-phosphate phosphatase
DLE04_00130	ENOG4105DJZ	UPF0182 protein
DLE04_00135	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DLE04_00170	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DLE04_00190	ENOG4105C4R	Atp-dependent dna helicase
DLE04_00200	ENOG4105CI3	gtp-binding protein typa
DLE04_00205	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DLE04_00210	ENOG4105C3G	gtp-binding protein
DLE04_00215	ENOG4105CGY	Dna recombination protein
DLE04_00225	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
DLE04_00230	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DLE04_00235	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DLE04_00240	ENOG4107GFK	fumarate
DLE04_00250	ENOG4108IAB	Phoh family
DLE04_00255	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DLE04_00275	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DLE04_00290	ENOG4106517	Short-chain dehydrogenase reductase Sdr
DLE04_00295	ENOG4105CPQ	Dehydrogenase
DLE04_00300	ENOG4105C01	Dihydroxy-acid dehydratase
DLE04_00340	ENOG4105CPQ	Dehydrogenase
DLE04_00365	ENOG4107T65	Integrase
DLE04_00375	ENOG4105C0D	helicase
DLE04_00440	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DLE04_00460	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DLE04_00465	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DLE04_00470	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DLE04_00475	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DLE04_00480	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DLE04_00495	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
DLE04_00500	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DLE04_00505	ENOG4105F8V	Hydrolase, tatD family
DLE04_00510	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DLE04_00540	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
DLE04_00545	ENOG4105C1G	acyl-Coa dehydrogenase
DLE04_00565	ENOG4107R13	MMPL domain protein
DLE04_00580	ENOG4108IXY	short-chain dehydrogenase reductase
DLE04_00595	ENOG4105BZU	Histidine kinase
DLE04_00600	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
DLE04_00610	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
DLE04_00615	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DLE04_00635	ENOG4105VEQ	Cold shock protein
DLE04_00645	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DLE04_00660	ENOG4105CGD	Nad-dependent epimerase dehydratase
DLE04_00670	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
DLE04_00685	ENOG4107R33	ppx gppa phosphatase
DLE04_00695	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
DLE04_00710	ENOG4105C8N	cysteinyl-tRNA synthetase
DLE04_00715	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DLE04_00720	ENOG4108VJ1	Transcriptional regulator (CarD family
DLE04_00730	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DLE04_00740	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DLE04_00750	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
DLE04_00755	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
DLE04_00760	ENOG4105I3K	Ferric uptake regulator, Fur family
DLE04_00765	ENOG4105PKJ	carbohydrate binding
DLE04_00770	ENOG4105KHC	sulfurtransferase
DLE04_00785	ENOG4107NHD	transcriptional regulator
DLE04_00790	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
DLE04_00800	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DLE04_00815	ENOG41090KN	UPF0303 protein
DLE04_00825	ENOG4105CPC	Aldo Keto reductase
DLE04_00840	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DLE04_00845	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DLE04_00855	ENOG4107QQG	Dehydrogenase
DLE04_00885	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DLE04_00900	ENOG4105BZ1	(ABC) transporter
DLE04_00910	ENOG4108PQP	glycosyl transferase group 1
DLE04_00925	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DLE04_00930	ENOG4105Q84	sucrose synthase
DLE04_00940	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
DLE04_00965	ENOG4105FAW	cDP-glucose 4,6-dehydratase
DLE04_01025	ENOG4108HHA	Transketolase
DLE04_01065	ENOG4105F0R	Cytidylyltransferase
DLE04_01070	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
DLE04_01080	ENOG4105D2T	synthase
DLE04_01085	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
DLE04_01105	ENOG4107QRG	dna polymerase iii
DLE04_01110	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DLE04_01125	ENOG4105CMR	udp-glucose 4-epimerase
DLE04_01140	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DLE04_01145	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DLE04_01150	ENOG4105DQR	SNARE associated Golgi
DLE04_01155	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DLE04_01160	ENOG4105KNI	merR family transcriptional Regulator
DLE04_01165	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DLE04_01170	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DLE04_01175	ENOG4105CFG	Acts as a chaperone (By similarity)
DLE04_01180	ENOG4105DF6	Fe-S oxidoreductase
DLE04_01205	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DLE04_01210	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DLE04_01220	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DLE04_01225	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DLE04_01230	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DLE04_01235	ENOG41084CH	50S ribosomal protein l34
DLE04_01245	ENOG41084DJ	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DLE04_01250	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DLE04_01260	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
DLE04_01265	ENOG4107QJE	Chromosome Partitioning Protein
DLE04_01270	ENOG4105FA0	parb-like partition protein
DLE04_01275	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DLE04_01280	ENOG4108E1C	hydrolase
DLE04_01285	ENOG4105K63	Thioredoxin
DLE04_01290	ENOG4105C3M	thioredoxin reductase
DLE04_01310	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DLE04_01325	ENOG4105BZ4	penicillin-binding protein
DLE04_01335	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
DLE04_01345	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DLE04_01350	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DLE04_01355	ENOG4105CDU	Replicative dna helicase
DLE04_01365	ENOG4105CSU	acyl-Coa dehydrogenase
DLE04_01370	ENOG4105DHP	deoxycytidine triphosphate deaminase
DLE04_01375	ENOG4108V0P	LemA family
DLE04_01380	ENOG4105D0M	Protease HtpX homolog
DLE04_01385	ENOG4105BZU	Histidine kinase
DLE04_01390	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DLE04_01395	ENOG4105ZJT	Cell division protein CrgA
DLE04_01420	ENOG4105CQC	Prephenate dehydratase
DLE04_01425	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DLE04_01430	ENOG4108K4B	hydrolase
DLE04_01460	ENOG4105WMR	Protein CrcB homolog
DLE04_01465	ENOG4107T6F	Xaa-Pro aminopeptidase
DLE04_01470	ENOG4108HHA	Transketolase
DLE04_01475	ENOG4108IUS	Transketolase
DLE04_01480	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DLE04_01485	ENOG4107Z96	xylose isomerase
DLE04_01530	ENOG4105EMU	Dehydrogenase
DLE04_01535	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
DLE04_01540	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
DLE04_01545	ENOG4105E2X	shikimate dehydrogenase
DLE04_01555	ENOG4105C2J	ABC transporter
DLE04_01560	ENOG4105CNN	ABC, transporter
DLE04_01565	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
DLE04_01570	ENOG4108NQD	
DLE04_01575	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
DLE04_01590	ENOG4105EF1	ribulokinase
DLE04_01625	ENOG4108RVA	ribokinase
DLE04_01630	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
DLE04_01645	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DLE04_01655	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
DLE04_01660	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
DLE04_01665	ENOG4105C5H	ABC transporter
DLE04_01670	ENOG4108TEB	UPF0114 protein
DLE04_01680	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
DLE04_01690	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DLE04_01700	ENOG4108Z6B	deaminase
DLE04_01705	ENOG4105C0X	amino acid
DLE04_01730	ENOG4105VZ8	Transcriptional regulator
DLE04_01750	ENOG4105WH1	Two component transcriptional regulator luxr family
DLE04_01775	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
DLE04_01780	ENOG4105CFH	Aspartokinase
DLE04_01790	ENOG4105C30	Nad-dependent epimerase dehydratase
DLE04_01795	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
DLE04_01800	ENOG4105DIN	metallophosphoesterase
DLE04_01805	ENOG4105KTH	gatB Yqey
DLE04_01835	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DLE04_01840	ENOG4107RCW	fructose-bisphosphate aldolase
DLE04_01845	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DLE04_01850	ENOG4105C12	Phosphoribosylglycinamide synthetase
DLE04_01855	ENOG4105C83	adenylosuccinate lyase
DLE04_01860	ENOG4105C8V	SAICAR synthetase
DLE04_01865	ENOG410839H	phosphoribosylformylglycinamidine synthase
DLE04_01870	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
DLE04_01875	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
DLE04_01910	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DLE04_01945	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DLE04_01975	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DLE04_01990	ENOG4105D9G	High-affinity
DLE04_02030	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DLE04_02050	ENOG4105K4H	Nlp p60 protein
DLE04_02055	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DLE04_02070	ENOG4105EUJ	GTP cyclohydrolase i
DLE04_02080	ENOG4105KRF	dihydroneopterin aldolase
DLE04_02085	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DLE04_02090	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DLE04_02095	ENOG4108IYU	L-aspartate oxidase
DLE04_02105	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
DLE04_02110	ENOG4105CRK	lysyL-tRNA synthetase
DLE04_02125	ENOG4105CQB	FAD linked oxidase domain protein
DLE04_02130	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
DLE04_02135	ENOG4108JWX	
DLE04_02140	ENOG4105II7	pyrroline-5-carboxylate reductase
DLE04_02185	ENOG4108RH7	phosphoglycerate mutase
DLE04_02190	ENOG4107QX9	Thiol disulfide interChange protein
DLE04_02195	ENOG4107QIV	Cytochrome c biogenesis protein
DLE04_02200	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
DLE04_02220	ENOG4105CEY	Amp-dependent synthetase and ligase
DLE04_02225	ENOG4108IPT	Naphthoate synthase
DLE04_02230	ENOG4107TCW	O-succinylbenzoate synthase
DLE04_02235	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
DLE04_02240	ENOG4105E4F	Isochorismate synthase
DLE04_02250	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DLE04_02260	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE04_02265	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DLE04_02270	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE04_02280	ENOG4107QIZ	NADH dehydrogenase
DLE04_02285	ENOG4108IEH	NADH dehydrogenase subunit g
DLE04_02290	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
DLE04_02295	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE04_02300	ENOG41087XN	oxidoreductase
DLE04_02305	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE04_02320	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DLE04_02335	ENOG4108VPT	UPF0234 protein
DLE04_02380	ENOG4107YCY	Transcriptional regulator
DLE04_02385	ENOG4108MGF	sugar kinase
DLE04_02390	ENOG4105D2M	Aldolase
DLE04_02395	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
DLE04_02405	ENOG4105CTX	dehydratase
DLE04_02410	ENOG4108JQ1	Dehydrogenase
DLE04_02415	ENOG4105DG4	malate L-lactate dehydrogenase
DLE04_02420	ENOG4107ZR7	Membrane
DLE04_02425	ENOG4105EAB	amino acid AbC transporter
DLE04_02430	ENOG4105E5Q	amino acid AbC transporter
DLE04_02435	ENOG4105CDA	abc transporter atp-binding protein
DLE04_02440	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
DLE04_02475	ENOG4105WDJ	50S ribosomal protein L33
DLE04_02480	ENOG410900P	UPF0336 protein
DLE04_02495	ENOG4107R4N	Cell wall formation (By similarity)
DLE04_02515	ENOG410683Z	Preprotein translocase SecE subunit
DLE04_02525	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DLE04_02530	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DLE04_02535	ENOG4108VZM	50s ribosomal protein L10
DLE04_02540	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DLE04_02550	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DLE04_02555	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DLE04_02560	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DLE04_02565	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
DLE04_02570	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DLE04_02575	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DLE04_02580	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DLE04_02585	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DLE04_02590	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DLE04_02595	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DLE04_02600	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DLE04_02615	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DLE04_02620	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DLE04_02625	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DLE04_02630	ENOG41082SA	50s ribosomal protein l29
DLE04_02635	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DLE04_02640	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DLE04_02650	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DLE04_02655	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DLE04_02660	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DLE04_02665	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DLE04_02670	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DLE04_02675	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DLE04_02680	ENOG410849U	50S ribosomal protein L30
DLE04_02685	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DLE04_02690	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DLE04_02695	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DLE04_02700	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DLE04_02725	ENOG4105EMN	RNA polymerase sigma factor
DLE04_02755	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DLE04_02760	ENOG41067V7	50S ribosomal protein L36
DLE04_02765	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DLE04_02770	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DLE04_02775	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DLE04_02780	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DLE04_02785	ENOG4108ZT0	50S ribosomal protein l17
DLE04_02790	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
DLE04_02800	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DLE04_02805	ENOG4108UJD	30S ribosomal protein S9
DLE04_02810	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DLE04_02815	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DLE04_02825	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DLE04_02830	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DLE04_02835	ENOG4105C0Z	ABC transporter
DLE04_02840	ENOG4108IV0	ABC, transporter
DLE04_02850	ENOG4105C32	Amino acid ABC transporter (Permease)
DLE04_02880	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DLE04_02885	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
DLE04_02890	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DLE04_02900	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DLE04_02915	ENOG4107QVP	Dehydrogenase
DLE04_02920	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DLE04_02940	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DLE04_02965	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
DLE04_02990	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
DLE04_03000	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
DLE04_03015	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DLE04_03030	ENOG4105C31	Tryptophanyl-tRNA synthetase
DLE04_03050	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DLE04_03055	ENOG4105C26	Dehydrogenase
DLE04_03060	ENOG4105C26	Dehydrogenase
DLE04_03070	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
DLE04_03080	ENOG4108JIK	carboxylase
DLE04_03085	ENOG4107WR6	Maf-like protein
DLE04_03095	ENOG4105D8K	carboxyl transferase
DLE04_03110	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DLE04_03115	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DLE04_03120	ENOG4107TB5	TRANSCRIPTIONal
DLE04_03125	ENOG4105K64	Glycosyl transferase, family 2
DLE04_03135	ENOG4105EY8	ABC transporter
DLE04_03145	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
DLE04_03150	ENOG4108URH	decarboxylase
DLE04_03160	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DLE04_03170	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DLE04_03175	ENOG4107ZBN	O-methyltransferase
DLE04_03180	ENOG4105C0H	protease
DLE04_03190	ENOG4105D1F	ATP-binding protein
DLE04_03200	ENOG4105CJW	magnesium transporter
DLE04_03215	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
DLE04_03230	ENOG4105C1J	atp-dependent rna helicase
DLE04_03250	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
DLE04_03260	ENOG4105C8N	cysteinyl-tRNA synthetase
DLE04_03270	ENOG4108Z4U	Ferredoxin
DLE04_03285	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DLE04_03290	ENOG4107RGC	Glycosyl transferase, family 2
DLE04_03305	ENOG4107QKV	phosphomannomutase
DLE04_03310	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
DLE04_03315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DLE04_03320	ENOG4105BZU	Histidine kinase
DLE04_03330	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DLE04_03370	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DLE04_03375	ENOG4105E0X	reductase
DLE04_03385	ENOG4105ETE	Transcriptional regulator (LacI family
DLE04_03390	ENOG4105C87	Aminotransferase class I and II
DLE04_03420	ENOG4105ETX	regulatoR
DLE04_03425	ENOG4105BZU	Histidine kinase
DLE04_03440	ENOG4105CDH	Citrulline--aspartate ligase
DLE04_03445	ENOG41081K0	peptidylprolyl cis-trans isomerase
DLE04_03455	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DLE04_03500	ENOG4107YJ4	chain length determinant protein
DLE04_03530	ENOG4108UW5	maltose o-acetyltransferase
DLE04_03565	ENOG4105EXC	Acyl-transferase
DLE04_03595	ENOG4105F0N	pyrophosphate phospho-hydrolase
DLE04_03605	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
DLE04_03635	ENOG4105D8X	mechanosensitive ion channel
DLE04_03655	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DLE04_03660	ENOG4108YZG	isomerase
DLE04_03675	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DLE04_03680	ENOG4107TYH	extracellular solute-binding protein family 1
DLE04_03685	ENOG4105D81	ABC transporter, permease
DLE04_03690	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
DLE04_03705	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DLE04_03715	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DLE04_03720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DLE04_03730	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DLE04_03735	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DLE04_03740	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DLE04_03750	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
DLE04_03755	ENOG4105DFF	Rod shape-determining protein mreb
DLE04_03760	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
DLE04_03770	ENOG4105CJN	penicillin-binding protein
DLE04_03775	ENOG4105CNI	cell division protein FtsW
DLE04_03780	ENOG4105C03	ribonuclease
DLE04_03785	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DLE04_03790	ENOG4105K46	50S ribosomal protein l27
DLE04_03795	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DLE04_03800	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DLE04_03805	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DLE04_03810	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DLE04_03815	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DLE04_03820	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DLE04_03825	ENOG4105C01	Dihydroxy-acid dehydratase
DLE04_03840	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DLE04_03845	ENOG4108JQ1	Dehydrogenase
DLE04_03850	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DLE04_03855	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DLE04_03860	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DLE04_03865	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DLE04_03870	ENOG4105CE9	30S ribosomal protein S2
DLE04_03875	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
DLE04_03880	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DLE04_03885	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DLE04_03895	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DLE04_03905	ENOG4105C26	Dehydrogenase
DLE04_03915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DLE04_03920	ENOG4105F38	ABC transporter, permease
DLE04_03935	ENOG4105CYW	agmatinase
DLE04_03945	ENOG4105DZP	Membrane-associated zinc metalloprotease
DLE04_03950	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
DLE04_03955	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DLE04_03965	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
DLE04_03980	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DLE04_03980	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DLE04_03985	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DLE04_03990	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DLE04_04000	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DLE04_04005	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DLE04_04010	ENOG4105C1V	Peptidase, M16
DLE04_04015	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DLE04_04040	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DLE04_04060	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
DLE04_04075	ENOG4105WBV	Transcriptional regulator
DLE04_04090	ENOG4107XFJ	UPF0246 protein
DLE04_04095	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
DLE04_04100	ENOG4105KC9	Modulates RecA activity (By similarity)
DLE04_04110	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DLE04_04115	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DLE04_04120	ENOG4105K70	DNA-binding protein
DLE04_04130	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DLE04_04135	ENOG4105CPF	Cell wall formation (By similarity)
DLE04_04150	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
DLE04_04160	ENOG4105VB9	50S ribosomal protein l28
DLE04_04165	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DLE04_04170	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
DLE04_04175	ENOG4108JJ9	ABC, transporter
DLE04_04180	ENOG4108JJ8	(ABC) transporter
DLE04_04190	ENOG4106H78	methyltransferase
DLE04_04195	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DLE04_04210	ENOG41084BZ	50S ribosomal protein L32
DLE04_04215	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DLE04_04225	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DLE04_04240	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
DLE04_04250	ENOG4105K5M	30s ribosomal protein S16
DLE04_04255	ENOG41082KU	UPF0109 protein
DLE04_04260	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DLE04_04265	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DLE04_04275	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DLE04_04280	ENOG4108JB8	alcohol dehydrogenase
DLE04_04285	ENOG4105C26	Dehydrogenase
DLE04_04310	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DLE04_04315	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DLE04_04320	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
DLE04_04325	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DLE04_04345	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DLE04_04360	ENOG4107VEG	TrkA-N domain protein
DLE04_04365	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DLE04_04370	ENOG4107QM5	aconitate hydratase
DLE04_04375	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DLE04_04380	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DLE04_04420	ENOG4107SN7	NLP P60 protein
DLE04_04425	ENOG4105JNK	Glycosyl transferase (Group 1
DLE04_04430	ENOG4108VB1	regulatoR
DLE04_04450	ENOG4105DKQ	ROK family
DLE04_04460	ENOG4105E9Q	Acyl-transferase
DLE04_04465	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DLE04_04470	ENOG4105N14	lysine exporter protein LysE YggA
DLE04_04475	ENOG4105C2W	permease
DLE04_04490	ENOG41060WC	Enoyl-CoA hydratase
DLE04_04510	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DLE04_04515	ENOG4105C5F	glutamine synthetase
DLE04_04530	ENOG4105E9Q	Acyl-transferase
DLE04_04535	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DLE04_04540	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DLE04_04545	ENOG4105EYF	MMPL domain protein
DLE04_04570	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DLE04_04575	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
DLE04_04585	ENOG4105BZ1	(ABC) transporter
DLE04_04590	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
DLE04_04600	ENOG4105CPC	Aldo Keto reductase
DLE04_04610	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
DLE04_04620	ENOG4107T4Z	adenosine kinase
DLE04_04630	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
DLE04_04635	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DLE04_04640	ENOG4105MCD	Part of cytochrome c oxidase, its function is
DLE04_04650	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DLE04_04655	ENOG4107EUI	c reductase, iron-sulfur
DLE04_04660	ENOG4107UDY	cytochrome C
DLE04_04665	ENOG4105CCU	oxidase (Subunit III)
DLE04_04675	ENOG4108I0Q	anthranilate phosphoribosyltransferase
DLE04_04690	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DLE04_04710	ENOG4105DFW	ABC transporter
DLE04_04715	ENOG4105C2J	ABC transporter
DLE04_04720	ENOG4108HWW	ABC transporter
DLE04_04735	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
DLE04_04750	ENOG4105CRQ	synthase (Component I)
DLE04_04760	ENOG4105C22	threonyL-tRNA synthetase
DLE04_04770	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DLE04_04780	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
DLE04_04785	ENOG4105E2K	Glycosyl transferase (Group 1
DLE04_04800	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
DLE04_04805	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
DLE04_04810	ENOG4105CDY	transcriptional regulatory protein
DLE04_04815	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
DLE04_04820	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DLE04_04825	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DLE04_04830	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DLE04_04835	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DLE04_04840	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DLE04_04845	ENOG4105C99	atpase involved in dna repair
DLE04_04850	ENOG4105C5X	domain protein
DLE04_04855	ENOG4105CUT	histidyl-tRNA synthetase
DLE04_04860	ENOG4105C9M	aspartyl-trna synthetase
DLE04_04870	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DLE04_04875	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DLE04_04885	ENOG4105E2X	shikimate dehydrogenase
DLE04_04895	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DLE04_04900	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DLE04_04905	ENOG4105D49	3-dehydroquinate synthase
DLE04_04910	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
DLE04_04915	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DLE04_04920	ENOG410803B	Involved in the transcription termination process (By similarity)
DLE04_04930	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
DLE04_04935	ENOG4105CXT	aspartate transcarbamylase
DLE04_04940	ENOG4105CD3	dihydroorotase
DLE04_04945	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DLE04_04950	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DLE04_04955	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
DLE04_04960	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DLE04_04965	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
DLE04_04970	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
DLE04_04975	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
DLE04_04985	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
DLE04_04995	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DLE04_05000	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DLE04_05010	ENOG4105DJV	ribulose-phosphate 3-epimerase
DLE04_05020	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DLE04_05025	ENOG4105EAC	phosphoserine phosphatase
DLE04_05030	ENOG4105DKW	ABC transporter
DLE04_05035	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DLE04_05040	ENOG4105C7N	Xanthine uracil vitamin C permease
DLE04_05045	ENOG4108VW9	Membrane
DLE04_05055	ENOG4105DQ4	alcohol dehydrogenase
DLE04_05060	ENOG4107W53	thymidine kinase
DLE04_05065	ENOG4105EXC	Acyl-transferase
DLE04_05070	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DLE04_05080	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DLE04_05085	ENOG4108FN7	Aldo keto reductase
DLE04_05105	ENOG4105C8N	cysteinyl-tRNA synthetase
DLE04_05115	ENOG4105C3R	Methionine synthase
DLE04_05120	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DLE04_05140	ENOG4107TMB	Transcriptional regulator
DLE04_05150	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DLE04_05165	ENOG4105HFS	5'-3' exonuclease
DLE04_05170	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
DLE04_05180	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DLE04_05200	ENOG4108UW8	fha domain-containing protein
DLE04_05205	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DLE04_05215	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DLE04_05225	ENOG4105KHN	chorismate mutase
DLE04_05235	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
DLE04_05240	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
DLE04_05260	ENOG4105DCF	alanine dehydrogenase
DLE04_05265	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DLE04_05270	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DLE04_05275	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DLE04_05315	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DLE04_05320	ENOG4105CH7	arginosuccinase
DLE04_05325	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
DLE04_05335	ENOG4105CAS	nag kinase
DLE04_05340	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
DLE04_05345	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DLE04_05350	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DLE04_05355	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
DLE04_05360	ENOG4108RWN	rrna methyltransferase
DLE04_05365	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DLE04_05370	ENOG41084BS	50S ribosomal protein L35
DLE04_05375	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
DLE04_05380	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
DLE04_05400	ENOG4105BZ1	(ABC) transporter
DLE04_05405	ENOG4105VG1	fes assembly suf system protein
DLE04_05410	ENOG4108UNV	SUF system FeS assembly protein, NifU family
DLE04_05415	ENOG4105C9B	Cysteine desulfurase
DLE04_05420	ENOG4105C3K	feS assembly ATPase SufC
DLE04_05430	ENOG4105JRK	feS assembly protein SufD
DLE04_05450	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DLE04_05475	ENOG4105BZA	Phosphoglycerate kinase
DLE04_05480	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DLE04_05485	ENOG4105CIE	May be required for sporulation (By similarity)
DLE04_05490	ENOG4105CHW	UPF0052 protein
DLE04_05495	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
DLE04_05500	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DLE04_05505	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DLE04_05510	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DLE04_05515	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
DLE04_05520	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DLE04_05535	ENOG4105KA0	thioesterase Superfamily protein
DLE04_05540	ENOG4108IV0	ABC, transporter
DLE04_05545	ENOG4105C0Z	ABC transporter
DLE04_05550	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DLE04_05555	ENOG4105C32	Amino acid ABC transporter (Permease)
DLE04_05585	ENOG4105CBC	glutamate synthase
DLE04_05595	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
DLE04_05610	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DLE04_05615	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DLE04_05620	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DLE04_05625	ENOG4105CRQ	synthase (Component I)
DLE04_05630	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DLE04_05635	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DLE04_05640	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
DLE04_05650	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DLE04_05655	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DLE04_05660	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DLE04_05665	ENOG4105C0B	DNA polymerase III (alpha subunit)
DLE04_05685	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DLE04_05695	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
DLE04_05700	ENOG4105DFA	alanine racemase domain protein
DLE04_05705	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DLE04_05710	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DLE04_05720	ENOG4105DFU	Cell wall formation (By similarity)
DLE04_05725	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DLE04_05735	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DLE04_05740	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DLE04_05750	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DLE04_05755	ENOG4105CJN	penicillin-binding protein
DLE04_05765	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DLE04_05770	ENOG4108V6E	Cell division protein mraZ
DLE04_05785	ENOG4105C0B	DNA polymerase III (alpha subunit)
DLE04_05825	ENOG4108YIQ	Alpha beta hydrolase
DLE04_05840	ENOG4105CKK	Glycosyl transferase, family 2
DLE04_05880	ENOG4105CAT	Cytidine monophosphate kinase
DLE04_05890	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
DLE04_05905	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DLE04_05910	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
DLE04_05915	ENOG4105CTQ	phosphohexokinase
DLE04_05925	ENOG4105FDR	Membrane
DLE04_05930	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DLE04_05940	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DLE04_05945	ENOG4107QYR	Signal peptidase i
DLE04_05950	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DLE04_05965	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
DLE04_05975	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DLE04_05980	ENOG4105C5H	ABC transporter
DLE04_05995	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DLE04_06005	ENOG4105DKQ	ROK family
DLE04_06010	ENOG4105ECY	inositol monophosphatase
DLE04_06045	ENOG4105CHR	reductase
DLE04_06065	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
DLE04_06075	ENOG4105JSC	dimethylmenaquinone methyltransferase
DLE04_06100	ENOG4105DRS	transport system, permease
DLE04_06120	ENOG4105DIA	mandelate racemase muconate lactonizing
DLE04_06135	ENOG4107WEA	mandelate racemase muconate lactonizing
DLE04_06140	ENOG4108JQ1	Dehydrogenase
DLE04_06155	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DLE04_06160	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DLE04_06170	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DLE04_06190	ENOG4105K4P	CoA-binding domain protein
DLE04_06200	ENOG4105G2U	Cupin 2, conserved barrel domain protein
DLE04_06220	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DLE04_06225	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DLE04_06245	ENOG4105E6M	Sulphatase-modifying factor protein
DLE04_06255	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
DLE04_06270	ENOG4105DET	Rhamnulokinase
DLE04_06290	ENOG4105DQ4	alcohol dehydrogenase
DLE04_06305	ENOG4108JQ7	(ABC) transporter
DLE04_06310	ENOG4105C3U	ABC transporter
DLE04_06320	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DLE04_06330	ENOG4107SCA	Formamidase (EC 3.5.1.49)
DLE04_06340	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
DLE04_06360	ENOG4105EFZ	amidohydrolase
DLE04_06365	ENOG4105C26	Dehydrogenase
DLE04_06370	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
DLE04_06380	ENOG4107TFB	basic membrane
DLE04_06385	ENOG4105UIB	(ABC) transporter
DLE04_06395	ENOG4108JQ9	ABC transporter
DLE04_06400	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
DLE04_06410	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
DLE04_06425	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
DLE04_06430	ENOG4105ERH	Fumarylacetoacetate hydrolase
DLE04_06455	ENOG4107YU2	histidine triad (hIT) protein
DLE04_06460	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DLE04_06465	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DLE04_06470	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
DLE04_06485	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DLE04_06490	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
DLE04_06505	ENOG4105KQC	Competence protein
DLE04_06510	ENOG4105C8T	Leucyl-tRNA synthetase
DLE04_06530	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DLE04_06535	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DLE04_06540	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DLE04_06545	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DLE04_06555	ENOG4105C10	Electron transfer flavoprotein
DLE04_06565	ENOG4105BZF	Glycosyl transferase (Group 1
DLE04_06570	ENOG4108MJN	Glycosyl Transferase
DLE04_06585	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DLE04_06590	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DLE04_06620	ENOG4105VEQ	Cold shock protein
DLE04_06645	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
DLE04_06655	ENOG4106448	streptomycin biosynthesis protein strI
DLE04_06660	ENOG4105D7K	pfkb domain protein
DLE04_06680	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DLE04_06705	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
DLE04_06710	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DLE04_06720	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
DLE04_06750	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
DLE04_06755	ENOG4107GZ4	SanA protein
DLE04_06765	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
DLE04_06780	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DLE04_06785	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
DLE04_06790	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DLE04_06810	ENOG4105C4K	Nad synthetase
DLE04_06815	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DLE04_06835	ENOG4105C9K	Endothelin-converting enzyme 1
DLE04_06845	ENOG4108JQ7	(ABC) transporter
DLE04_06850	ENOG4105C3U	ABC transporter
DLE04_06865	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DLE04_06875	ENOG4105C57	major facilitator superfamily
DLE04_06880	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DLE04_06900	ENOG4105CXN	decarboxylase
DLE04_06915	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DLE04_06920	ENOG4105E2Z	phosphate ABC transporter (Permease
DLE04_06935	ENOG4105BZU	Histidine kinase
DLE04_06945	ENOG4105QE3	oxidoreductase
DLE04_06950	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DLE04_06965	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
DLE04_06975	ENOG4108V1U	phospholipid-binding protein
DLE04_07030	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DLE04_07100	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DLE04_07105	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DLE04_07110	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DLE04_07115	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DLE04_07120	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DLE04_07125	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
DLE04_07130	ENOG4106DE0	ATP synthase
DLE04_07135	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
DLE04_07150	ENOG4105ESV	Glycosyl transferase, family 4
DLE04_07155	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DLE04_07165	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DLE04_07170	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DLE04_07175	ENOG4105VFB	Binds the 23S rRNA (By similarity)
DLE04_07190	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DLE04_07195	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
DLE04_07200	ENOG4105D6E	homoserine dehydrogenase
DLE04_07210	ENOG4105C75	arginyL-tRNA synthetase
DLE04_07245	ENOG4108UT2	hemolysin iii
DLE04_07255	ENOG4105EXC	Acyl-transferase
DLE04_07265	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DLE04_07270	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DLE04_07275	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
DLE04_07300	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
DLE04_07315	ENOG4105DBV	ornithine carbamoyltransferase
DLE04_07320	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DLE04_07325	ENOG4105W8H	transhydrogenase (subunit alpha
DLE04_07330	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DLE04_07335	ENOG4105C72	UPF0176 protein
DLE04_07340	ENOG4105EUB	pirin domain protein