locus-tag	class	description
IMCC26256_111	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMCC26256_111000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC26256_111001	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMCC26256_111002	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMCC26256_111003	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC26256_111005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMCC26256_111010	COG4968	Prepilin-type N-terminal cleavage methylation domain
IMCC26256_111011	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IMCC26256_111016	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMCC26256_111017	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMCC26256_111018	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMCC26256_111019	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IMCC26256_111020	COG0006	proline dipeptidase activity
IMCC26256_111021	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMCC26256_111022	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC26256_111025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMCC26256_111026	COG0540	Belongs to the ATCase OTCase family
IMCC26256_111027	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMCC26256_111028	COG0505	Belongs to the CarA family
IMCC26256_111029	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMCC26256_11103	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IMCC26256_111030	COG0167	dihydroorotate dehydrogenase activity
IMCC26256_111031	COG0284	orotidine-5'-phosphate decarboxylase activity
IMCC26256_111033	COG0194	GDP metabolic process
IMCC26256_111034	COG1758	RNA polymerase activity
IMCC26256_111036	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMCC26256_111038	COG0242	peptide deformylase activity
IMCC26256_111039	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMCC26256_111043	COG0315	cyclic pyranopterin monophosphate synthase activity
IMCC26256_111043	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMCC26256_111047	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC26256_111047	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC26256_111048	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMCC26256_111049	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMCC26256_111052	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMCC26256_111053	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IMCC26256_111054	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMCC26256_111055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC26256_111056	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMCC26256_111057	COG0072	phenylalanine-tRNA ligase activity
IMCC26256_111058	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMCC26256_111059	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMCC26256_111060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMCC26256_111061	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMCC26256_111062	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMCC26256_111063	COG1438	arginine binding
IMCC26256_111064	COG0137	argininosuccinate synthase activity
IMCC26256_111065	COG0165	Argininosuccinate lyase
IMCC26256_111066	COG2124	cytochrome p450
IMCC26256_111067	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IMCC26256_111068	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMCC26256_111075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMCC26256_111075	COG2755	lipolytic protein G-D-S-L family
IMCC26256_111088	COG0674	pyruvate-flavodoxin oxidoreductase activity
IMCC26256_111088	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IMCC26256_111089	COG1013	pyruvate-flavodoxin oxidoreductase activity
IMCC26256_111094	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMCC26256_111095	COG0497	DNA recombination
IMCC26256_11110	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IMCC26256_111101	COG0504	CTP synthase activity
IMCC26256_111104	COG1994	Peptidase M50
IMCC26256_111106	COG0180	Tryptophanyl-tRNA synthetase
IMCC26256_111109	COG1187	pseudouridine synthase activity
IMCC26256_111111	COG0287	Prephenate dehydrogenase
IMCC26256_111112	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IMCC26256_111115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMCC26256_111117	COG1160	GTP binding
IMCC26256_111118	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC26256_111120	COG2124	cytochrome p450
IMCC26256_111126	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC26256_111127	COG0509	glycine decarboxylation via glycine cleavage system
IMCC26256_111128	COG1716	ATPase activity
IMCC26256_111132	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC26256_111133	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC26256_111133	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC26256_111137	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IMCC26256_111139	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IMCC26256_111143	COG0805	protein transport
IMCC26256_111144	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMCC26256_111152	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IMCC26256_111153	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IMCC26256_111154	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IMCC26256_111156	COG4122	O-methyltransferase activity
IMCC26256_111157	COG1222	aaa ATPase
IMCC26256_111163	COG0037	tRNA processing
IMCC26256_111173	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMCC26256_111174	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMCC26256_111175	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IMCC26256_111176	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26256_111180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMCC26256_111181	COG0109	protoheme IX farnesyltransferase activity
IMCC26256_111182	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC26256_111187	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111193	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_1112	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMCC26256_111200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC26256_111203	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMCC26256_111213	COG4608	Belongs to the ABC transporter superfamily
IMCC26256_111214	COG0444	Belongs to the ABC transporter superfamily
IMCC26256_111215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC26256_111216	COG0601	transmembrane transport
IMCC26256_111218	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC26256_111219	COG0149	triose-phosphate isomerase activity
IMCC26256_111220	COG0126	phosphoglycerate kinase activity
IMCC26256_111221	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMCC26256_111222	COG1660	Displays ATPase and GTPase activities
IMCC26256_111223	COG0322	excinuclease ABC activity
IMCC26256_111224	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMCC26256_111225	COG2226	methyltransferase
IMCC26256_111226	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMCC26256_111227	COG0556	nucleotide-excision repair
IMCC26256_111228	COG0237	dephospho-CoA kinase activity
IMCC26256_111229	COG2197	response regulator
IMCC26256_111235	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111238	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMCC26256_111241	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IMCC26256_111245	COG0135	phosphoribosylanthranilate isomerase activity
IMCC26256_111246	COG0134	indole-3-glycerol-phosphate synthase activity
IMCC26256_111248	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC26256_111249	COG0140	phosphoribosyl-ATP diphosphatase activity
IMCC26256_111249	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMCC26256_11125	COG0243	molybdopterin cofactor binding
IMCC26256_111252	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMCC26256_111253	COG0131	Imidazoleglycerol-phosphate dehydratase
IMCC26256_111254	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMCC26256_111255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMCC26256_111257	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMCC26256_111258	COG0456	acetyltransferase
IMCC26256_111259	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IMCC26256_11126	COG2755	lipolytic protein G-D-S-L family
IMCC26256_11126	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMCC26256_111262	COG1331	Highly conserved protein containing a thioredoxin domain
IMCC26256_111264	COG2124	cytochrome p450
IMCC26256_11127	COG0577	efflux transmembrane transporter activity
IMCC26256_111273	COG2205	protein histidine kinase activity
IMCC26256_111279	COG0455	bacterial-type flagellum organization
IMCC26256_11128	COG1136	(ABC) transporter
IMCC26256_11128	COG0577	efflux transmembrane transporter activity
IMCC26256_111283	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMCC26256_111290	COG0756	dUTP diphosphatase activity
IMCC26256_111291	COG0730	response to heat
IMCC26256_111294	COG0175	sulfate reduction
IMCC26256_111297	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_111300	COG0463	Glycosyl transferase, family 2
IMCC26256_111306	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IMCC26256_111309	COG0483	inositol monophosphate 1-phosphatase activity
IMCC26256_11131	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IMCC26256_111310	COG0183	Belongs to the thiolase family
IMCC26256_111312	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMCC26256_111312	COG2146	nitrite reductase [NAD(P)H] activity
IMCC26256_111314	COG0588	phosphoglycerate mutase activity
IMCC26256_111315	COG0248	Ppx GppA phosphatase
IMCC26256_111319	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC26256_111320	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111321	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111322	COG2365	Tyrosine phosphatase family
IMCC26256_111327	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111329	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IMCC26256_111330	COG4106	trans-aconitate 2-methyltransferase activity
IMCC26256_111333	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26256_111334	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111341	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC26256_111348	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC26256_111348	COG1024	Enoyl-CoA hydratase
IMCC26256_111353	COG0110	maltose O-acetyltransferase activity
IMCC26256_111355	COG0183	Belongs to the thiolase family
IMCC26256_111356	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IMCC26256_111362	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111363	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC26256_111367	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111370	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IMCC26256_111372	COG0069	glutamate synthase activity
IMCC26256_111372	COG0067	glutamate synthase
IMCC26256_111372	COG0070	glutamate synthase
IMCC26256_111373	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111377	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC26256_111381	COG0277	FAD linked oxidase domain protein
IMCC26256_111383	COG0560	Phosphoserine phosphatase
IMCC26256_111385	COG0243	molybdopterin cofactor binding
IMCC26256_111386	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC26256_111387	COG0154	amidase activity
IMCC26256_11139	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMCC26256_111395	COG0395	ABC-type sugar transport system, permease component
IMCC26256_111396	COG1175	transmembrane transport
IMCC26256_111398	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMCC26256_11140	COG1136	(ABC) transporter
IMCC26256_111403	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMCC26256_111409	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMCC26256_11141	COG0577	efflux transmembrane transporter activity
IMCC26256_111414	COG2161	toxin-antitoxin pair type II binding
IMCC26256_111415	COG2026	Addiction module toxin, RelE StbE family
IMCC26256_11142	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMCC26256_111429	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IMCC26256_11143	COG2070	2-Nitropropane dioxygenase
IMCC26256_111430	COG0406	alpha-ribazole phosphatase activity
IMCC26256_111430	COG0328	RNA-DNA hybrid ribonuclease activity
IMCC26256_111432	COG0328	RNA-DNA hybrid ribonuclease activity
IMCC26256_111432	COG0406	alpha-ribazole phosphatase activity
IMCC26256_111434	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IMCC26256_111448	COG0243	molybdopterin cofactor binding
IMCC26256_111449	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMCC26256_111452	COG2154	pterin-4-alpha-carbinolamine dehydratase
IMCC26256_111453	COG1404	Belongs to the peptidase S8 family
IMCC26256_111459	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC26256_111460	COG0358	DNA primase activity
IMCC26256_111461	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IMCC26256_111462	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMCC26256_111462	COG0574	Belongs to the PEP-utilizing enzyme family
IMCC26256_111464	COG0423	glycine-tRNA ligase activity
IMCC26256_111465	COG1381	Involved in DNA repair and RecF pathway recombination
IMCC26256_111466	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC26256_111471	COG1845	cytochrome c oxidase, subunit III
IMCC26256_111476	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMCC26256_111479	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMCC26256_111481	COG1420	regulation of RNA biosynthetic process
IMCC26256_111483	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111484	COG0481	GTPase activity
IMCC26256_111485	COG0268	Binds directly to 16S ribosomal RNA
IMCC26256_111489	COG1555	photosystem II stabilization
IMCC26256_111490	COG0495	leucyl-tRNA aminoacylation
IMCC26256_111492	COG2226	methyltransferase
IMCC26256_111493	COG3119	arylsulfatase activity
IMCC26256_111495	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IMCC26256_111496	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMCC26256_111497	COG0107	imidazoleglycerol-phosphate synthase activity
IMCC26256_111498	COG0799	negative regulation of ribosome biogenesis
IMCC26256_11150	COG0038	chloride channel
IMCC26256_111500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMCC26256_111503	COG0456	acetyltransferase
IMCC26256_111505	COG0542	response to heat
IMCC26256_111506	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMCC26256_111507	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMCC26256_111508	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMCC26256_111509	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IMCC26256_111510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC26256_111511	COG1530	ribonuclease E activity
IMCC26256_111515	COG0772	Belongs to the SEDS family
IMCC26256_111520	COG0105	UTP biosynthetic process
IMCC26256_111521	COG0285	dihydrofolate synthase activity
IMCC26256_111522	COG0525	valine-tRNA ligase activity
IMCC26256_111523	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMCC26256_111524	COG0740	serine-type endopeptidase activity
IMCC26256_111525	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMCC26256_111526	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMCC26256_111530	COG0546	phosphoglycolate phosphatase activity
IMCC26256_111531	COG0758	DNA mediated transformation
IMCC26256_11154	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMCC26256_111542	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMCC26256_111542	COG2755	lipolytic protein G-D-S-L family
IMCC26256_111547	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IMCC26256_111548	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26256_111549	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26256_111550	COG3300	MHYT domain
IMCC26256_111550	COG5001	Diguanylate cyclase
IMCC26256_111556	COG0745	RESPONSE REGULATOR receiver
IMCC26256_111557	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111560	COG5001	Diguanylate cyclase
IMCC26256_111563	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMCC26256_111564	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMCC26256_111565	COG1234	tRNA 3'-trailer cleavage
IMCC26256_111566	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMCC26256_111567	COG0009	L-threonylcarbamoyladenylate synthase
IMCC26256_111571	COG2723	6-phospho-beta-galactosidase activity
IMCC26256_111573	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMCC26256_11158	COG0590	tRNA wobble adenosine to inosine editing
IMCC26256_111583	COG0300	oxidoreductase activity
IMCC26256_111585	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111586	COG5285	phytanoyl-CoA dioxygenase
IMCC26256_111590	COG0667	Aldo Keto reductase
IMCC26256_111594	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
IMCC26256_111595	COG2814	Major facilitator Superfamily
IMCC26256_111598	COG1946	Acyl-CoA thioesterase
IMCC26256_111600	COG2755	lipolytic protein G-D-S-L family
IMCC26256_111600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMCC26256_111601	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC26256_111602	COG1678	Uncharacterized ACR, COG1678
IMCC26256_111603	COG2326	polyphosphate kinase activity
IMCC26256_111610	COG1131	(ABC) transporter
IMCC26256_111615	COG2130	NADP-dependent
IMCC26256_111618	COG1741	Belongs to the pirin family
IMCC26256_11162	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMCC26256_111621	COG1309	transcriptional regulator
IMCC26256_111623	COG2135	peptidase activity
IMCC26256_111626	COG0450	alkyl hydroperoxide reductase
IMCC26256_111628	COG2177	Part of the ABC transporter FtsEX involved in
IMCC26256_111629	COG2884	Cell division ATP-binding protein ftsE
IMCC26256_11163	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMCC26256_111631	COG0653	protein targeting
IMCC26256_111633	COG1040	competence protein
IMCC26256_111634	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMCC26256_111635	COG2222	sugar isomerase
IMCC26256_111637	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC26256_11164	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMCC26256_111641	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC26256_111647	COG0778	Nitroreductase
IMCC26256_111647	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IMCC26256_111648	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IMCC26256_111648	COG0778	Nitroreductase
IMCC26256_111649	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMCC26256_111653	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMCC26256_111654	COG1316	TRANSCRIPTIONal
IMCC26256_111658	COG4770	biotin carboxylase activity
IMCC26256_111662	COG1024	Enoyl-CoA hydratase
IMCC26256_111665	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IMCC26256_111666	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMCC26256_111667	COG1024	Enoyl-CoA hydratase
IMCC26256_111669	COG4946	Tricorn protease homolog
IMCC26256_111669	COG0793	Belongs to the peptidase S41A family
IMCC26256_111670	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_111671	COG2226	methyltransferase
IMCC26256_111676	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111678	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IMCC26256_111679	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMCC26256_111680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMCC26256_111682	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC26256_111683	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC26256_111684	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC26256_111685	COG0356	it plays a direct role in the translocation of protons across the membrane
IMCC26256_111688	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26256_111689	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMCC26256_111690	COG0698	ribose 5-phosphate isomerase
IMCC26256_111691	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_111692	COG0297	glycogen (starch) synthase activity
IMCC26256_111695	COG0489	protein tyrosine kinase activity
IMCC26256_111697	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMCC26256_111705	COG1132	(ABC) transporter
IMCC26256_111707	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMCC26256_11171	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC26256_111710	COG0254	rRNA binding
IMCC26256_111712	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
IMCC26256_111714	COG4221	oxidoreductase activity
IMCC26256_111715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMCC26256_111716	COG0460	homoserine dehydrogenase
IMCC26256_111718	COG0018	arginyl-trna synthetase
IMCC26256_111719	COG3706	GGDEF domain
IMCC26256_111724	COG0514	ATP-dependent DNA helicase (RecQ)
IMCC26256_111730	COG0514	ATP-dependent DNA helicase (RecQ)
IMCC26256_11174	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC26256_111741	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMCC26256_111744	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26256_111747	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111749	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IMCC26256_111750	COG0477	Major facilitator Superfamily
IMCC26256_111752	COG0730	response to heat
IMCC26256_111753	COG1597	lipid kinase activity
IMCC26256_111761	COG0489	protein tyrosine kinase activity
IMCC26256_111761	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC26256_111762	COG0640	Transcriptional regulator
IMCC26256_111763	COG1104	cysteine desulfurase activity
IMCC26256_111767	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMCC26256_111768	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMCC26256_111770	COG3088	subunit of a heme lyase
IMCC26256_111771	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC26256_111772	COG1138	Cytochrome C-type biogenesis protein
IMCC26256_111775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC26256_111777	COG4133	protoheme IX ABC transporter activity
IMCC26256_111778	COG3764	Sortase (surface protein transpeptidase)
IMCC26256_111780	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMCC26256_11179	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC26256_111790	COG0667	Aldo Keto reductase
IMCC26256_111792	COG0183	Belongs to the thiolase family
IMCC26256_111794	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC26256_111796	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IMCC26256_111797	COG1074	ATP-dependent DNA helicase activity
IMCC26256_111798	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMCC26256_111799	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC26256_111799	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IMCC26256_1118	COG2124	cytochrome p450
IMCC26256_111800	COG2814	Major facilitator Superfamily
IMCC26256_111802	COG3527	Alpha-acetolactate decarboxylase
IMCC26256_111805	COG3361	conserved protein (COG2071)
IMCC26256_11181	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMCC26256_111833	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_11184	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMCC26256_111842	COG0183	Belongs to the thiolase family
IMCC26256_111843	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111844	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111845	COG2205	protein histidine kinase activity
IMCC26256_111846	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26256_111849	COG2070	2-Nitropropane dioxygenase
IMCC26256_111852	COG1024	Enoyl-CoA hydratase
IMCC26256_111854	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111855	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111857	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC26256_111859	COG1564	THIamine pyrophosphokinase
IMCC26256_111860	COG1840	ABC-type Fe3 transport system, periplasmic component
IMCC26256_111861	COG1178	ABC-type Fe3 transport system permease component
IMCC26256_111862	COG3842	ATPase activity
IMCC26256_111863	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC26256_111865	COG2205	protein histidine kinase activity
IMCC26256_111866	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC26256_111866	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC26256_111870	COG0259	pyridoxamine-phosphate oxidase activity
IMCC26256_111872	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111874	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26256_111882	COG0402	S-adenosylhomocysteine deaminase activity
IMCC26256_111886	COG2211	Major facilitator Superfamily
IMCC26256_111888	COG2226	methyltransferase
IMCC26256_111889	COG1169	isochorismate synthase
IMCC26256_11189	COG2894	cell division
IMCC26256_111891	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IMCC26256_111903	COG0440	acetolactate synthase activity
IMCC26256_111905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMCC26256_111905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMCC26256_111906	COG0129	dihydroxy-acid dehydratase activity
IMCC26256_111909	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC26256_111910	COG0154	amidase activity
IMCC26256_111911	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC26256_111914	COG0477	Major facilitator Superfamily
IMCC26256_111915	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_111916	COG2815	serine threonine protein kinase
IMCC26256_111916	COG0515	serine threonine protein kinase
IMCC26256_111920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC26256_111924	COG0482	sulfurtransferase activity
IMCC26256_111928	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC26256_111928	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC26256_111929	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IMCC26256_111930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMCC26256_111932	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC26256_111934	COG0646	methionine synthase
IMCC26256_111934	COG1410	methionine synthase
IMCC26256_11194	COG0489	protein tyrosine kinase activity
IMCC26256_11194	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC26256_111947	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC26256_111948	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMCC26256_11195	COG0316	Belongs to the HesB IscA family
IMCC26256_111950	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_111951	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_111952	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_111953	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMCC26256_111957	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111958	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_111959	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC26256_111960	COG0396	ATPase activity
IMCC26256_111961	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMCC26256_111962	COG0822	iron-sulfur transferase activity
IMCC26256_111966	COG0396	ATPase activity
IMCC26256_111968	COG0719	Fe-S assembly protein
IMCC26256_111969	COG0719	Fe-S assembly protein
IMCC26256_111970	COG1615	UPF0182 protein
IMCC26256_111972	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMCC26256_111974	COG1077	Cell shape determining protein MreB Mrl
IMCC26256_111976	COG0314	molybdopterin synthase activity
IMCC26256_111981	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMCC26256_111982	COG2814	Major facilitator Superfamily
IMCC26256_111983	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMCC26256_111986	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IMCC26256_111988	COG0745	RESPONSE REGULATOR receiver
IMCC26256_111989	COG5002	protein histidine kinase activity
IMCC26256_111990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMCC26256_111991	COG0581	inorganic phosphate transmembrane transporter activity
IMCC26256_111992	COG0573	inorganic phosphate transmembrane transporter activity
IMCC26256_111993	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMCC26256_111994	COG0704	Plays a role in the regulation of phosphate uptake
IMCC26256_111996	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC26256_111997	COG2205	protein histidine kinase activity
IMCC26256_111998	COG0745	RESPONSE REGULATOR receiver
IMCC26256_112	COG0592	DNA-directed DNA polymerase activity
IMCC26256_112004	COG1595	DNA-templated transcription, initiation
IMCC26256_11201	COG0745	RESPONSE REGULATOR receiver
IMCC26256_112012	COG0745	RESPONSE REGULATOR receiver
IMCC26256_112014	COG4867	von Willebrand factor, type A
IMCC26256_112019	COG1053	succinate dehydrogenase
IMCC26256_112026	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC26256_112029	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMCC26256_112030	COG0277	FAD linked oxidase domain protein
IMCC26256_112031	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC26256_112035	COG0596	Alpha beta hydrolase
IMCC26256_112036	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMCC26256_112037	COG0039	L-malate dehydrogenase activity
IMCC26256_112039	COG0538	isocitrate dehydrogenase activity
IMCC26256_112041	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMCC26256_112042	COG0138	bifunctional purine biosynthesis protein purh
IMCC26256_112044	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMCC26256_112045	COG0045	succinate-CoA ligase (ADP-forming) activity
IMCC26256_112046	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC26256_112046	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC26256_112048	COG0210	DNA helicase
IMCC26256_112050	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC26256_112050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC26256_112051	COG0516	GMP reductase activity
IMCC26256_112052	COG0494	nUDIX hydrolase
IMCC26256_112056	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMCC26256_112057	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC26256_112060	COG0802	atpase or kinase
IMCC26256_112061	COG1573	uracil-dna glycosylase
IMCC26256_112062	COG2267	carboxylic ester hydrolase activity
IMCC26256_112063	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMCC26256_112064	COG2239	Acts as a magnesium transporter
IMCC26256_112065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMCC26256_112065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMCC26256_112066	COG0736	holo-[acyl-carrier-protein] synthase activity
IMCC26256_112067	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMCC26256_112068	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC26256_112069	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMCC26256_11207	COG2962	Rard protein
IMCC26256_112070	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMCC26256_112077	COG0101	tRNA pseudouridine synthase activity
IMCC26256_112078	COG0203	ribosomal protein L17
IMCC26256_11208	COG2909	trisaccharide binding
IMCC26256_112080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMCC26256_112081	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMCC26256_11209	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC26256_11209	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMCC26256_112096	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMCC26256_112107	COG1216	Glycosyl transferase, family 2
IMCC26256_112114	COG1215	transferase activity, transferring glycosyl groups
IMCC26256_112115	COG1215	transferase activity, transferring glycosyl groups
IMCC26256_112119	COG1045	serine acetyltransferase
IMCC26256_112124	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_112125	COG0456	acetyltransferase
IMCC26256_112126	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26256_112127	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMCC26256_112129	COG1086	Polysaccharide biosynthesis protein
IMCC26256_112131	COG0024	Methionine aminopeptidase
IMCC26256_112132	COG0563	adenylate kinase activity
IMCC26256_112134	COG0200	Binds to the 23S rRNA
IMCC26256_112135	COG1841	ribosomal large subunit assembly
IMCC26256_112136	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMCC26256_112137	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMCC26256_112138	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMCC26256_112139	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMCC26256_112140	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMCC26256_112141	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMCC26256_112142	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMCC26256_112143	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMCC26256_112144	COG0255	Belongs to the universal ribosomal protein uL29 family
IMCC26256_112146	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMCC26256_112147	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMCC26256_112148	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMCC26256_112149	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMCC26256_11215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC26256_112150	COG0089	rRNA binding
IMCC26256_112151	COG0088	Forms part of the polypeptide exit tunnel
IMCC26256_112152	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMCC26256_112154	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC26256_112155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMCC26256_112156	COG0049	tRNA binding
IMCC26256_112157	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMCC26256_112158	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMCC26256_112159	COG0085	RNA polymerase activity
IMCC26256_11216	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IMCC26256_112160	COG0222	ribosome binding
IMCC26256_112161	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMCC26256_112162	COG0081	regulation of translation
IMCC26256_112163	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMCC26256_112164	COG0250	Participates in transcription elongation, termination and antitermination
IMCC26256_112165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC26256_112167	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMCC26256_112168	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC26256_112174	COG1666	GTP binding
IMCC26256_112177	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC26256_112179	COG1007	ATP synthesis coupled electron transport
IMCC26256_112181	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMCC26256_112182	COG0713	ATP synthesis coupled electron transport
IMCC26256_112184	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMCC26256_112186	COG0649	NAD binding
IMCC26256_112187	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112188	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112189	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112192	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMCC26256_112193	COG0713	ATP synthesis coupled electron transport
IMCC26256_112194	COG0839	Belongs to the complex I subunit 6 family
IMCC26256_112195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112196	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMCC26256_112197	COG1034	ATP synthesis coupled electron transport
IMCC26256_112198	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IMCC26256_112200	COG0649	NAD binding
IMCC26256_112201	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112202	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112203	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26256_112204	COG0644	oxidoreductase
IMCC26256_112215	COG3119	arylsulfatase activity
IMCC26256_112217	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMCC26256_112218	COG0113	porphobilinogen synthase activity
IMCC26256_112220	COG0181	hydroxymethylbilane synthase activity
IMCC26256_112221	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IMCC26256_112222	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IMCC26256_112222	COG1648	precorrin-2 dehydrogenase activity
IMCC26256_112224	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26256_112234	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_11224	COG1111	helicase
IMCC26256_11224	COG1205	dead DEAH box helicase
IMCC26256_112240	COG0735	belongs to the Fur family
IMCC26256_112244	COG3443	Belongs to the bacterial solute-binding protein 9 family
IMCC26256_112244	COG0803	Belongs to the bacterial solute-binding protein 9 family
IMCC26256_112245	COG1121	(ABC) transporter
IMCC26256_112246	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMCC26256_112249	COG1177	transmembrane transport
IMCC26256_11225	COG1316	TRANSCRIPTIONal
IMCC26256_112250	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC26256_112253	COG3842	ATPase activity
IMCC26256_112254	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26256_112257	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC26256_112258	COG0156	8-amino-7-oxononanoate synthase activity
IMCC26256_112259	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IMCC26256_112261	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC26256_112263	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IMCC26256_11227	COG0569	domain protein
IMCC26256_112272	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMCC26256_112273	COG0581	inorganic phosphate transmembrane transporter activity
IMCC26256_112285	COG2070	2-Nitropropane dioxygenase
IMCC26256_112286	COG2072	flavoprotein involved in K transport
IMCC26256_112287	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMCC26256_112289	COG0529	Catalyzes the synthesis of activated sulfate
IMCC26256_112290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC26256_112293	COG0047	phosphoribosylformylglycinamidine synthase activity
IMCC26256_112294	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC26256_112295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMCC26256_112296	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMCC26256_112298	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMCC26256_112299	COG0542	response to heat
IMCC26256_11230	COG0531	amino acid
IMCC26256_112300	COG0789	Transcriptional regulator
IMCC26256_112301	COG0484	heat shock protein binding
IMCC26256_112303	COG0443	Heat shock 70 kDa protein
IMCC26256_112304	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMCC26256_112305	COG0247	lactate metabolic process
IMCC26256_112305	COG2181	nitrate reductase activity
IMCC26256_112306	COG0717	Belongs to the dCTP deaminase family
IMCC26256_112307	COG3214	Protein conserved in bacteria
IMCC26256_11231	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IMCC26256_112310	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IMCC26256_112311	COG3619	membrane
IMCC26256_112318	COG0745	RESPONSE REGULATOR receiver
IMCC26256_11232	COG0586	Pfam SNARE associated Golgi protein
IMCC26256_112324	COG0305	Participates in initiation and elongation during chromosome replication
IMCC26256_112325	COG0359	binds to the 23S rRNA
IMCC26256_112326	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMCC26256_112327	COG0629	single-stranded DNA binding
IMCC26256_112328	COG0360	Binds together with S18 to 16S ribosomal RNA
IMCC26256_11233	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMCC26256_11233	COG1754	DNA topoisomerase type I activity
IMCC26256_112330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IMCC26256_112334	COG1260	myo-inositol-1-phosphate synthase
IMCC26256_112341	COG1307	EDD domain protein, DegV family
IMCC26256_112345	COG3118	belongs to the thioredoxin family
IMCC26256_112345	COG0492	ferredoxin-NADP+ reductase activity
IMCC26256_112346	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMCC26256_112346	COG3409	Peptidoglycan-binding domain 1 protein
IMCC26256_112348	COG1192	Involved in chromosome partitioning
IMCC26256_112349	COG0357	Ribosomal RNA small subunit methyltransferase G
IMCC26256_11235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMCC26256_112352	COG0594	ribonuclease P activity
IMCC26256_11236	COG0470	DNA polymerase III
IMCC26256_11239	COG1595	DNA-templated transcription, initiation
IMCC26256_11242	COG0037	tRNA processing
IMCC26256_11244	COG0302	gtp cyclohydrolase
IMCC26256_11245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMCC26256_11247	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMCC26256_11250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMCC26256_11251	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IMCC26256_11253	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IMCC26256_11254	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMCC26256_11255	COG0142	geranyltranstransferase activity
IMCC26256_11256	COG0542	response to heat
IMCC26256_11258	COG0546	phosphoglycolate phosphatase activity
IMCC26256_11259	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMCC26256_11260	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IMCC26256_11263	COG1329	Transcriptional regulator
IMCC26256_11264	COG4956	integral membrane protein (PIN domain superfamily)
IMCC26256_11265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMCC26256_11265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IMCC26256_11266	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMCC26256_11267	COG0215	cysteine-tRNA ligase activity
IMCC26256_11268	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC26256_11272	COG1929	Belongs to the glycerate kinase type-1 family
IMCC26256_11273	COG1215	transferase activity, transferring glycosyl groups
IMCC26256_11275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMCC26256_11276	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IMCC26256_11277	COG0672	)-iron permease
IMCC26256_11283	COG0459	protein refolding
IMCC26256_11292	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IMCC26256_11293	COG1051	belongs to the nudix hydrolase family
IMCC26256_11296	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC26256_11297	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC26256_113	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC26256_11301	COG0583	DNA-binding transcription factor activity
IMCC26256_11307	COG0312	modulator of DNA gyrase
IMCC26256_11308	COG0312	modulator of DNA gyrase
IMCC26256_11309	COG1968	undecaprenyl-diphosphatase activity
IMCC26256_11312	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IMCC26256_11313	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMCC26256_11314	COG0303	'Molybdopterin
IMCC26256_11315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMCC26256_11316	COG0315	cyclic pyranopterin monophosphate synthase activity
IMCC26256_1132	COG3046	protein related to deoxyribodipyrimidine photolyase
IMCC26256_11322	COG0316	Belongs to the HesB IscA family
IMCC26256_11322	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IMCC26256_11330	COG0531	amino acid
IMCC26256_11337	COG4412	M6 family metalloprotease domain protein
IMCC26256_11337	COG3291	Pkd domain containing protein
IMCC26256_11338	COG1744	ABC transporter substrate-binding protein PnrA-like
IMCC26256_11353	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_11362	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_11363	COG1215	transferase activity, transferring glycosyl groups
IMCC26256_11368	COG0726	polysaccharide deacetylase
IMCC26256_11375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMCC26256_11377	COG1024	Enoyl-CoA hydratase
IMCC26256_11378	COG0012	GTP binding
IMCC26256_1138	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC26256_11381	COG2002	toxin-antitoxin pair type II binding
IMCC26256_11382	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC26256_11383	COG0084	hydrolase, TatD family'
IMCC26256_11384	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMCC26256_11386	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMCC26256_11388	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC26256_11390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMCC26256_11391	COG0193	aminoacyl-tRNA hydrolase activity
IMCC26256_11393	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMCC26256_11394	COG3956	TIGRFAM MazG family protein
IMCC26256_11396	COG4221	oxidoreductase activity
IMCC26256_11397	COG0148	phosphopyruvate hydratase activity
IMCC26256_1140	COG0183	Belongs to the thiolase family
IMCC26256_11401	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMCC26256_11403	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMCC26256_11411	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC26256_11412	COG3118	belongs to the thioredoxin family
IMCC26256_11418	COG2301	Belongs to the HpcH HpaI aldolase family
IMCC26256_11421	COG1132	(ABC) transporter
IMCC26256_11422	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_11424	COG2030	dehydratase
IMCC26256_11427	COG1131	(ABC) transporter
IMCC26256_11430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMCC26256_11431	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC26256_11433	COG1132	(ABC) transporter
IMCC26256_11434	COG1132	(ABC) transporter
IMCC26256_11436	COG3845	ABC transporter
IMCC26256_1144	COG0515	serine threonine protein kinase
IMCC26256_1144	COG2815	serine threonine protein kinase
IMCC26256_11441	COG0785	Cytochrome C biogenesis protein
IMCC26256_11448	COG3119	arylsulfatase activity
IMCC26256_1145	COG0768	penicillin binding
IMCC26256_11450	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IMCC26256_11452	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMCC26256_11453	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26256_11457	COG1228	amidohydrolase
IMCC26256_11464	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMCC26256_11468	COG0419	ATPase involved in DNA repair
IMCC26256_1147	COG0631	protein serine/threonine phosphatase activity
IMCC26256_11483	COG2161	toxin-antitoxin pair type II binding
IMCC26256_1149	COG1131	(ABC) transporter
IMCC26256_1149	COG1716	ATPase activity
IMCC26256_1149	COG0842	Transport permease protein
IMCC26256_11492	COG0545	Peptidyl-prolyl cis-trans isomerase
IMCC26256_11497	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC26256_11499	COG1322	Protein conserved in bacteria
IMCC26256_115	COG0187	DNA topoisomerase II activity
IMCC26256_1151	COG3609	addiction module antidote protein, CC2985 family
IMCC26256_11510	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26256_11512	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMCC26256_11514	COG1278	Cold shock
IMCC26256_11515	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26256_11516	COG0028	Belongs to the TPP enzyme family
IMCC26256_1152	COG2337	Toxic component of a toxin-antitoxin (TA) module
IMCC26256_11522	COG3119	arylsulfatase activity
IMCC26256_11525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC26256_11526	COG2837	iron assimilation
IMCC26256_11529	COG1234	tRNA 3'-trailer cleavage
IMCC26256_11530	COG0596	Alpha beta hydrolase
IMCC26256_11535	COG3976	FMN-binding domain protein
IMCC26256_11535	COG1053	succinate dehydrogenase
IMCC26256_11539	COG2124	cytochrome p450
IMCC26256_11540	COG0667	Aldo Keto reductase
IMCC26256_11549	COG2267	carboxylic ester hydrolase activity
IMCC26256_11552	COG3804	dihydrodipicolinate reductase
IMCC26256_11556	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IMCC26256_11566	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_11567	COG3250	beta-galactosidase activity
IMCC26256_11568	COG0183	Belongs to the thiolase family
IMCC26256_11570	COG2119	membrane
IMCC26256_11572	COG0596	Alpha beta hydrolase
IMCC26256_11586	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMCC26256_11588	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMCC26256_11591	COG4974	Belongs to the 'phage' integrase family
IMCC26256_116	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC26256_11600	COG1063	alcohol dehydrogenase
IMCC26256_11601	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_11605	COG0004	ammonium transporteR
IMCC26256_11607	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMCC26256_11608	COG1131	(ABC) transporter
IMCC26256_11612	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMCC26256_11614	COG0702	epimerase
IMCC26256_11615	COG0596	Alpha beta hydrolase
IMCC26256_11622	COG1404	Belongs to the peptidase S8 family
IMCC26256_11625	COG1024	Enoyl-CoA hydratase
IMCC26256_11632	COG0788	formyltetrahydrofolate deformylase activity
IMCC26256_11640	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_11642	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IMCC26256_11647	COG0673	inositol 2-dehydrogenase activity
IMCC26256_11656	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_11658	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_11659	COG0513	Belongs to the DEAD box helicase family
IMCC26256_1166	COG1957	nucleoside hydrolase
IMCC26256_11661	COG0436	Aminotransferase
IMCC26256_11663	COG1970	mechanosensitive ion channel activity
IMCC26256_11666	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC26256_11668	COG0066	3-isopropylmalate dehydratase activity
IMCC26256_11669	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMCC26256_1167	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26256_11673	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMCC26256_11674	COG0410	ABC transporter
IMCC26256_11679	COG0473	3-isopropylmalate dehydrogenase activity
IMCC26256_11681	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC26256_11683	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC26256_11689	COG0776	regulation of translation
IMCC26256_11691	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMCC26256_11694	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMCC26256_11696	COG0383	alpha-mannosidase activity
IMCC26256_11700	COG4274	PFAM GYD family protein
IMCC26256_11702	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMCC26256_11708	COG0587	DNA-directed DNA polymerase activity
IMCC26256_11709	COG3300	MHYT domain
IMCC26256_11709	COG5001	Diguanylate cyclase
IMCC26256_11711	COG2720	vancomycin resistance protein
IMCC26256_11712	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_11713	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMCC26256_11715	COG0183	Belongs to the thiolase family
IMCC26256_11726	COG2197	response regulator
IMCC26256_11729	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_11732	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMCC26256_11735	COG0708	Exodeoxyribonuclease III
IMCC26256_11739	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC26256_11749	COG3345	alpha-galactosidase
IMCC26256_11750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMCC26256_11751	COG1085	galactose-1-phosphate uridylyltransferase
IMCC26256_11755	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26256_11757	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMCC26256_11758	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IMCC26256_11760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMCC26256_11761	COG1461	Dihydroxyacetone kinase
IMCC26256_11762	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMCC26256_11763	COG0742	ribosomal rna small subunit methyltransferase
IMCC26256_11764	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMCC26256_11767	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IMCC26256_11768	COG0416	fatty acid biosynthetic process
IMCC26256_11769	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC26256_11770	COG0571	ribonuclease III activity
IMCC26256_11774	COG0668	transmembrane transport
IMCC26256_11777	COG0228	four-way junction DNA binding
IMCC26256_11779	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMCC26256_1178	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_1178	COG1216	Glycosyl transferase, family 2
IMCC26256_11780	COG0336	Belongs to the RNA methyltransferase TrmD family
IMCC26256_11781	COG0335	large ribosomal subunit rRNA binding
IMCC26256_11783	COG0792	nuclease activity
IMCC26256_11785	COG1024	Enoyl-CoA hydratase
IMCC26256_11787	COG0758	DNA mediated transformation
IMCC26256_11788	COG0606	chelatase, subunit chli
IMCC26256_11789	COG4974	Belongs to the 'phage' integrase family
IMCC26256_11790	COG1191	sigma factor activity
IMCC26256_11793	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMCC26256_11794	COG0528	UMP kinase activity
IMCC26256_11795	COG0233	cytoplasmic translational termination
IMCC26256_11796	COG4589	Belongs to the CDS family
IMCC26256_11797	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IMCC26256_11799	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMCC26256_1180	COG0463	Glycosyl transferase, family 2
IMCC26256_11803	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMCC26256_11806	COG0442	prolyl-tRNA aminoacylation
IMCC26256_11809	COG0779	Required for maturation of 30S ribosomal subunits
IMCC26256_1181	COG1216	Glycosyl transferase, family 2
IMCC26256_1181	COG0463	Glycosyl transferase, family 2
IMCC26256_11810	COG0195	Participates in both transcription termination and antitermination
IMCC26256_11811	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC26256_11811	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC26256_11812	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMCC26256_11814	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMCC26256_11815	COG0196	riboflavin kinase activity
IMCC26256_11817	COG1185	polyribonucleotide nucleotidyltransferase activity
IMCC26256_11818	COG0612	Peptidase, M16
IMCC26256_11819	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMCC26256_11824	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMCC26256_11826	COG1674	ftsk spoiiie
IMCC26256_11827	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC26256_11829	COG1546	Belongs to the CinA family
IMCC26256_11829	COG1058	Belongs to the CinA family
IMCC26256_11831	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMCC26256_11833	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC26256_11836	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMCC26256_11839	COG2171	N-acyltransferase activity
IMCC26256_1184	COG1072	(Pantothenic acid kinase))
IMCC26256_11844	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMCC26256_11856	COG0386	Belongs to the glutathione peroxidase family
IMCC26256_11858	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IMCC26256_1186	COG0166	Belongs to the GPI family
IMCC26256_11861	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_11865	COG0745	RESPONSE REGULATOR receiver
IMCC26256_1187	COG0077	Prephenate dehydratase
IMCC26256_11875	COG0114	fumarate hydratase activity
IMCC26256_11876	COG0300	oxidoreductase activity
IMCC26256_11878	COG0444	Belongs to the ABC transporter superfamily
IMCC26256_1188	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMCC26256_11881	COG0747	negative chemotaxis
IMCC26256_11885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMCC26256_11887	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26256_11890	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26256_11894	COG2124	cytochrome p450
IMCC26256_11897	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IMCC26256_11899	COG1024	Enoyl-CoA hydratase
IMCC26256_1190	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_11900	COG0789	Transcriptional regulator
IMCC26256_11902	COG1024	Enoyl-CoA hydratase
IMCC26256_11904	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMCC26256_11905	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_11909	COG1940	carbohydrate kinase activity
IMCC26256_1191	COG1960	acyl-CoA dehydrogenase activity
IMCC26256_11910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC26256_11915	COG1024	Enoyl-CoA hydratase
IMCC26256_11916	COG2124	cytochrome p450
IMCC26256_11919	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMCC26256_1192	COG0366	Alpha amylase catalytic
IMCC26256_11927	COG0436	Aminotransferase
IMCC26256_1193	COG3832	glyoxalase III activity
IMCC26256_11930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC26256_11932	COG1946	Acyl-CoA thioesterase
IMCC26256_11934	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IMCC26256_11938	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMCC26256_11942	COG2001	Belongs to the MraZ family
IMCC26256_11943	COG0275	rRNA processing
IMCC26256_11946	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMCC26256_11947	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMCC26256_11948	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26256_11949	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMCC26256_11950	COG0772	Belongs to the SEDS family
IMCC26256_11951	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMCC26256_11952	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMCC26256_11953	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMCC26256_11954	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMCC26256_11955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMCC26256_11957	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMCC26256_11958	COG1799	cell septum assembly
IMCC26256_11959	COG0762	integral membrane protein
IMCC26256_11961	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMCC26256_11962	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IMCC26256_11963	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMCC26256_11964	COG0564	pseudouridine synthase activity
IMCC26256_11969	COG2205	protein histidine kinase activity
IMCC26256_11970	COG1959	2 iron, 2 sulfur cluster binding
IMCC26256_11974	COG0215	cysteine-tRNA ligase activity
IMCC26256_11975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMCC26256_11979	COG1560	Kdo2-lipid A biosynthetic process
IMCC26256_1198	COG1024	Enoyl-CoA hydratase
IMCC26256_11980	COG0438	transferase activity, transferring glycosyl groups
IMCC26256_11981	COG1704	LemA family
IMCC26256_11982	COG0501	Belongs to the peptidase M48B family
IMCC26256_11983	COG1470	cell adhesion involved in biofilm formation
IMCC26256_11985	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMCC26256_11986	COG0217	transcriptional regulatory protein
IMCC26256_11987	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMCC26256_11988	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IMCC26256_11989	COG0632	four-way junction helicase activity
IMCC26256_11990	COG2255	four-way junction helicase activity
IMCC26256_11991	COG1862	Preprotein translocase
IMCC26256_11993	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC26256_11994	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMCC26256_11995	COG0124	histidyl-tRNA synthetase
IMCC26256_11996	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)