locus-tag	class	description
Asera_00040	COG0488	(ABC) transporter
Asera_00060	COG2814	Major facilitator Superfamily
Asera_00090	COG0604	alcohol dehydrogenase
Asera_00090	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_00090	COG3321	synthase
Asera_00160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Asera_00210	COG2172	sigma factor antagonist activity
Asera_00220	COG1191	sigma factor activity
Asera_00280	COG1672	PFAM Archaeal ATPase
Asera_00280	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asera_00310	COG4770	biotin carboxylase activity
Asera_00370	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asera_00370	COG1473	amidohydrolase
Asera_00390	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_00390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_00400	COG2815	serine threonine protein kinase
Asera_00400	COG0515	serine threonine protein kinase
Asera_00410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asera_00420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Asera_00440	COG2030	dehydratase
Asera_00450	COG2197	response regulator
Asera_00460	COG2409	Drug exporters of the RND superfamily
Asera_00510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asera_00530	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_00530	COG0204	Acyl-transferase
Asera_00540	COG3321	synthase
Asera_00540	COG0604	alcohol dehydrogenase
Asera_00560	COG0475	glutathione-regulated potassium exporter activity
Asera_00620	COG2132	Multicopper oxidase
Asera_00640	COG3226	Transcriptional regulator
Asera_00660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Asera_00670	COG1012	belongs to the aldehyde dehydrogenase family
Asera_00680	COG1012	belongs to the aldehyde dehydrogenase family
Asera_00730	COG2018	Roadblock/LC7 domain
Asera_00750	COG0747	negative chemotaxis
Asera_00780	COG4608	Belongs to the ABC transporter superfamily
Asera_00790	COG0444	Belongs to the ABC transporter superfamily
Asera_00810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_00820	COG2154	pterin-4-alpha-carbinolamine dehydratase
Asera_00840	COG1053	succinate dehydrogenase
Asera_00870	COG4762	Protein conserved in bacteria
Asera_00880	COG0494	nUDIX hydrolase
Asera_00910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_00930	COG0640	Transcriptional regulator
Asera_00990	COG2076	Multidrug Resistance protein
Asera_01040	COG0012	GTP binding
Asera_01070	COG4585	Histidine kinase
Asera_01080	COG2197	response regulator
Asera_01090	COG2409	Drug exporters of the RND superfamily
Asera_01130	COG2169	Transcriptional regulator
Asera_01130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Asera_01170	COG1132	(ABC) transporter
Asera_01200	COG0525	valine-tRNA ligase activity
Asera_01230	COG1322	Protein conserved in bacteria
Asera_01260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Asera_01270	COG1570	exodeoxyribonuclease VII activity
Asera_01280	COG1722	exodeoxyribonuclease VII activity
Asera_01320	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Asera_01340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Asera_01380	COG1331	Highly conserved protein containing a thioredoxin domain
Asera_01430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_01490	COG1051	belongs to the nudix hydrolase family
Asera_01540	COG0537	adenosine 5'-monophosphoramidase activity
Asera_01550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asera_01600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Asera_01620	COG3467	pyridoxamine 5'-phosphate
Asera_01630	COG2755	lipolytic protein G-D-S-L family
Asera_01650	COG0183	Belongs to the thiolase family
Asera_01700	COG0076	glutamate decarboxylase activity
Asera_01750	COG0328	RNA-DNA hybrid ribonuclease activity
Asera_01770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asera_01790	COG1252	NADH dehydrogenase
Asera_01820	COG0714	Associated with various cellular activities
Asera_01890	COG0148	phosphopyruvate hydratase activity
Asera_02030	COG2409	Drug exporters of the RND superfamily
Asera_02090	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_02180	COG0326	Molecular chaperone. Has ATPase activity
Asera_02200	COG1846	Transcriptional regulator
Asera_02210	COG0655	NAD(P)H dehydrogenase (quinone) activity
Asera_02230	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Asera_02240	COG0529	Catalyzes the synthesis of activated sulfate
Asera_02250	COG0730	response to heat
Asera_02340	COG2755	lipolytic protein G-D-S-L family
Asera_02360	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_02380	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Asera_02440	COG3321	synthase
Asera_02440	COG0604	alcohol dehydrogenase
Asera_02450	COG1309	transcriptional regulator
Asera_02480	COG1218	3'(2'),5'-bisphosphate nucleotidase
Asera_02490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asera_02500	COG0193	aminoacyl-tRNA hydrolase activity
Asera_02510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Asera_02520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Asera_02530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Asera_02580	COG0488	(ABC) transporter
Asera_02590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Asera_02610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Asera_02630	COG0084	hydrolase, TatD family'
Asera_02640	COG1253	flavin adenine dinucleotide binding
Asera_02650	COG1253	flavin adenine dinucleotide binding
Asera_02660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asera_02750	COG0443	Heat shock 70 kDa protein
Asera_02810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_02960	COG1674	ftsk spoiiie
Asera_03090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Asera_03180	COG3842	ATPase activity
Asera_03260	COG1937	Protein conserved in bacteria
Asera_03270	COG3883	PFAM NLP P60 protein
Asera_03270	COG0791	NLP P60 protein
Asera_03290	COG2318	DinB family
Asera_03330	COG0142	geranyltranstransferase activity
Asera_03430	COG4152	abc transporter atp-binding protein
Asera_03440	COG1668	transmembrane transport
Asera_03450	COG0667	Aldo Keto reductase
Asera_03480	COG2814	Major facilitator Superfamily
Asera_03490	COG0583	DNA-binding transcription factor activity
Asera_03530	COG2271	Major facilitator Superfamily
Asera_03550	COG0242	peptide deformylase activity
Asera_03590	COG1760	l-serine dehydratase
Asera_03600	COG2814	Major facilitator Superfamily
Asera_03660	COG2017	converts alpha-aldose to the beta-anomer
Asera_03670	COG1733	regulation of RNA biosynthetic process
Asera_03700	COG0259	pyridoxamine-phosphate oxidase activity
Asera_03720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Asera_03750	COG1131	(ABC) transporter
Asera_03770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Asera_03820	COG2252	PERMEase
Asera_03840	COG2205	protein histidine kinase activity
Asera_03850	COG0745	RESPONSE REGULATOR receiver
Asera_03930	COG2814	Major facilitator Superfamily
Asera_03960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Asera_03970	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Asera_03990	COG1278	Cold shock
Asera_04010	COG0584	glycerophosphoryl diester phosphodiesterase
Asera_04070	COG4991	sh3 domain protein
Asera_04130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Asera_04140	COG1595	DNA-templated transcription, initiation
Asera_04150	COG1252	NADH dehydrogenase
Asera_04160	COG1522	sequence-specific DNA binding
Asera_04230	COG0456	acetyltransferase
Asera_04240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_04260	COG1737	Transcriptional regulator
Asera_04270	COG3876	Protein conserved in bacteria
Asera_04280	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_04290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Asera_04320	COG0459	protein refolding
Asera_04380	COG1278	Cold shock
Asera_04400	COG0456	acetyltransferase
Asera_04430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Asera_04450	COG0640	Transcriptional regulator
Asera_04480	COG1131	(ABC) transporter
Asera_04490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asera_04500	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Asera_04600	COG0681	Belongs to the peptidase S26 family
Asera_04610	COG4608	Belongs to the ABC transporter superfamily
Asera_04620	COG0444	Belongs to the ABC transporter superfamily
Asera_04650	COG4166	transmembrane transport
Asera_04660	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_04680	COG1349	DNA-binding transcription factor activity
Asera_04700	COG1940	carbohydrate kinase activity
Asera_04750	COG1595	DNA-templated transcription, initiation
Asera_04800	COG1733	regulation of RNA biosynthetic process
Asera_04860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Asera_04870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Asera_04900	COG1309	transcriptional regulator
Asera_05000	COG0456	acetyltransferase
Asera_05040	COG0110	maltose O-acetyltransferase activity
Asera_05110	COG1754	DNA topoisomerase type I activity
Asera_05110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Asera_05160	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Asera_05180	COG1366	Belongs to the anti-sigma-factor antagonist family
Asera_05190	COG1111	helicase
Asera_05190	COG1205	dead DEAH box helicase
Asera_05200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_05280	COG0488	(ABC) transporter
Asera_05300	COG0789	Transcriptional regulator
Asera_05450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_05500	COG1733	regulation of RNA biosynthetic process
Asera_05540	COG1051	belongs to the nudix hydrolase family
Asera_05590	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_05600	COG1595	DNA-templated transcription, initiation
Asera_05620	COG0560	Phosphoserine phosphatase
Asera_05690	COG0506	proline dehydrogenase activity
Asera_05700	COG0649	NAD binding
Asera_05740	COG1174	glycine betaine transport
Asera_05750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asera_05760	COG0517	IMP dehydrogenase activity
Asera_05760	COG1125	glycine betaine transport
Asera_05780	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_05800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Asera_05810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Asera_05970	COG1404	Belongs to the peptidase S8 family
Asera_06010	COG0302	gtp cyclohydrolase
Asera_06020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asera_06030	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Asera_06100	COG1774	PSP1 C-terminal conserved region
Asera_06160	COG1175	transmembrane transport
Asera_06170	COG0395	ABC-type sugar transport system, permease component
Asera_06190	COG0584	glycerophosphoryl diester phosphodiesterase
Asera_06200	COG0546	phosphoglycolate phosphatase activity
Asera_06220	COG0456	acetyltransferase
Asera_06220	COG1846	Transcriptional regulator
Asera_06260	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_06280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Asera_06290	COG2027	D-alanyl-D-alanine carboxypeptidase
Asera_06310	COG0037	tRNA processing
Asera_06350	COG3263	regulation of cellular component size
Asera_06390	COG1309	transcriptional regulator
Asera_06400	COG2814	Major facilitator Superfamily
Asera_06420	COG3104	oligopeptide transport
Asera_06430	COG1653	transport
Asera_06440	COG0395	ABC-type sugar transport system, permease component
Asera_06450	COG1175	transmembrane transport
Asera_06490	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Asera_06530	COG3842	ATPase activity
Asera_06560	COG0215	cysteine-tRNA ligase activity
Asera_06580	COG0114	fumarate hydratase activity
Asera_06610	COG0163	prenyltransferase activity
Asera_06640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Asera_06650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Asera_06660	COG3548	integral membrane protein
Asera_06680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Asera_06710	COG0789	Transcriptional regulator
Asera_06740	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Asera_06800	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_06810	COG3246	L-lysine catabolic process to acetate
Asera_06850	COG4044	May play a role in the intracellular transport of hydrophobic ligands
Asera_06870	COG0025	NhaP-type Na H and K H
Asera_06960	COG0745	RESPONSE REGULATOR receiver
Asera_06970	COG0456	acetyltransferase
Asera_07000	COG1131	(ABC) transporter
Asera_07020	COG4585	Histidine kinase
Asera_07030	COG2197	response regulator
Asera_07040	COG0842	Transport permease protein
Asera_07040	COG1131	(ABC) transporter
Asera_07040	COG1716	ATPase activity
Asera_07070	COG1846	Transcriptional regulator
Asera_07090	COG3321	synthase
Asera_07090	COG0604	alcohol dehydrogenase
Asera_07100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_07120	COG0667	Aldo Keto reductase
Asera_07160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Asera_07250	COG1653	transport
Asera_07260	COG1653	transport
Asera_07280	COG1175	transmembrane transport
Asera_07290	COG0673	inositol 2-dehydrogenase activity
Asera_07300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Asera_07310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asera_07320	COG0494	nUDIX hydrolase
Asera_07390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Asera_07400	COG0596	Alpha beta hydrolase
Asera_07420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asera_07470	COG0577	efflux transmembrane transporter activity
Asera_07470	COG1136	(ABC) transporter
Asera_07480	COG0577	efflux transmembrane transporter activity
Asera_07490	COG1595	DNA-templated transcription, initiation
Asera_07510	COG2267	carboxylic ester hydrolase activity
Asera_07550	COG1366	Belongs to the anti-sigma-factor antagonist family
Asera_07570	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Asera_07590	COG1793	dna ligase
Asera_07590	COG3285	dna ligase
Asera_07700	COG1309	transcriptional regulator
Asera_07740	COG0367	asparagine synthase
Asera_07770	COG1072	(Pantothenic acid kinase))
Asera_07790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asera_07800	COG3387	PFAM Glycoside hydrolase 15-related
Asera_07810	COG0439	Biotin carboxylase
Asera_07830	COG0640	Transcriptional regulator
Asera_07950	COG1191	sigma factor activity
Asera_08080	COG0702	epimerase
Asera_08140	COG4585	Histidine kinase
Asera_08190	COG1064	alcohol dehydrogenase
Asera_08220	COG1595	DNA-templated transcription, initiation
Asera_08230	COG0583	DNA-binding transcription factor activity
Asera_08350	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_08360	COG0667	Aldo Keto reductase
Asera_08390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asera_08400	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_08430	COG2197	response regulator
Asera_08460	COG0235	Class ii aldolase
Asera_08470	COG0477	Major facilitator Superfamily
Asera_08480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_08490	COG0765	amino acid transport
Asera_08500	COG0765	amino acid transport
Asera_08570	COG0673	inositol 2-dehydrogenase activity
Asera_08630	COG0789	Transcriptional regulator
Asera_08640	COG2130	NADP-dependent
Asera_08650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Asera_08660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Asera_08710	COG0778	Nitroreductase
Asera_08720	COG1051	belongs to the nudix hydrolase family
Asera_08740	COG0596	Alpha beta hydrolase
Asera_08780	COG1597	lipid kinase activity
Asera_08800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_08810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_08870	COG1309	transcriptional regulator
Asera_08880	COG0686	Belongs to the AlaDH PNT family
Asera_08910	COG2186	Transcriptional regulator
Asera_08920	COG2050	protein possibly involved in aromatic compounds catabolism
Asera_08940	COG2226	methyltransferase
Asera_08950	COG1024	Enoyl-CoA hydratase
Asera_08960	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_09010	COG0778	Nitroreductase
Asera_09010	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
Asera_09040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Asera_09090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Asera_09160	COG1131	(ABC) transporter
Asera_09190	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Asera_09200	COG0047	phosphoribosylformylglycinamidine synthase activity
Asera_09210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Asera_09220	COG0640	Transcriptional regulator
Asera_09240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Asera_09250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Asera_09280	COG0151	Belongs to the GarS family
Asera_09290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Asera_09320	COG1733	regulation of RNA biosynthetic process
Asera_09360	COG0191	fructose-bisphosphate aldolase activity
Asera_09380	COG1355	regulation of microtubule-based process
Asera_09440	COG0586	Pfam SNARE associated Golgi protein
Asera_09460	COG0640	Transcriptional regulator
Asera_09470	COG1619	proteins homologs of microcin C7 resistance protein MccF
Asera_09480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Asera_09490	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_09520	COG0542	response to heat
Asera_09580	COG0475	glutathione-regulated potassium exporter activity
Asera_09610	COG0789	Transcriptional regulator
Asera_09620	COG0484	heat shock protein binding
Asera_09630	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Asera_09640	COG0443	Heat shock 70 kDa protein
Asera_09660	COG2181	nitrate reductase activity
Asera_09660	COG0247	lactate metabolic process
Asera_09740	COG0717	Belongs to the dCTP deaminase family
Asera_09900	COG2186	Transcriptional regulator
Asera_09990	COG3328	transposase activity
Asera_10000	COG3903	Transcriptional regulator
Asera_10000	COG3629	intracellular signal transduction
Asera_10080	COG0656	L-ascorbic acid biosynthetic process
Asera_10100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asera_10230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asera_10240	COG1834	amidinotransferase
Asera_10250	COG1522	sequence-specific DNA binding
Asera_10280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Asera_10370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asera_10370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asera_10390	COG0242	peptide deformylase activity
Asera_10450	COG0210	DNA helicase
Asera_10500	COG5002	protein histidine kinase activity
Asera_10510	COG0745	RESPONSE REGULATOR receiver
Asera_10520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Asera_10610	COG0022	dehydrogenase e1 component
Asera_10620	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_10660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Asera_10670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Asera_10680	COG1984	allophanate hydrolase subunit 2
Asera_10690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Asera_10730	COG1960	acyl-CoA dehydrogenase activity
Asera_10750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Asera_10820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Asera_10880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Asera_10960	COG0521	Mo-molybdopterin cofactor biosynthetic process
Asera_10970	COG0315	cyclic pyranopterin monophosphate synthase activity
Asera_10980	COG5001	Diguanylate cyclase
Asera_10980	COG1716	ATPase activity
Asera_11020	COG2186	Transcriptional regulator
Asera_11040	COG0667	Aldo Keto reductase
Asera_11060	COG0305	Participates in initiation and elongation during chromosome replication
Asera_11070	COG1796	DNA polymerase
Asera_11070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Asera_11110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asera_11140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_11160	COG0359	binds to the 23S rRNA
Asera_11170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Asera_11180	COG0629	single-stranded DNA binding
Asera_11190	COG0360	Binds together with S18 to 16S ribosomal RNA
Asera_11250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_11310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_11320	COG2027	D-alanyl-D-alanine carboxypeptidase
Asera_11340	COG2268	Band 7 protein
Asera_11350	COG2132	Multicopper oxidase
Asera_11430	COG0617	tRNA 3'-terminal CCA addition
Asera_11470	COG0433	COG0433 Predicted ATPase
Asera_11490	COG1595	DNA-templated transcription, initiation
Asera_11520	COG3118	belongs to the thioredoxin family
Asera_11530	COG3409	Peptidoglycan-binding domain 1 protein
Asera_11530	COG0860	N-Acetylmuramoyl-L-alanine amidase
Asera_11550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_11560	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asera_11570	COG2382	esterase
Asera_11570	COG3507	Belongs to the glycosyl hydrolase 43 family
Asera_11570	COG3693	PFAM glycoside hydrolase, family 10
Asera_11590	COG1247	-acetyltransferase
Asera_11610	COG1192	Involved in chromosome partitioning
Asera_11620	COG0357	Ribosomal RNA small subunit methyltransferase G
Asera_11660	COG0594	ribonuclease P activity
Asera_11670	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Asera_11680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Asera_11690	COG0592	DNA-directed DNA polymerase activity
Asera_11700	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Asera_11710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Asera_11720	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Asera_11750	COG1595	DNA-templated transcription, initiation
Asera_11770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Asera_11830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Asera_11880	COG0402	S-adenosylhomocysteine deaminase activity
Asera_11980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_12090	COG0439	Biotin carboxylase
Asera_12100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asera_12120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_12150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Asera_12160	COG1960	acyl-CoA dehydrogenase activity
Asera_12190	COG1881	PFAM PEBP family protein
Asera_12230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_12240	COG0598	Magnesium transport protein CorA
Asera_12290	COG1309	transcriptional regulator
Asera_12310	COG0183	Belongs to the thiolase family
Asera_12380	COG0515	serine threonine protein kinase
Asera_12380	COG2815	serine threonine protein kinase
Asera_12390	COG0515	serine threonine protein kinase
Asera_12400	COG0768	penicillin binding
Asera_12430	COG1716	ATPase activity
Asera_12440	COG1716	ATPase activity
Asera_12440	COG1716	ATPase activity
Asera_12450	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_12460	COG1309	transcriptional regulator
Asera_12470	COG4221	oxidoreductase activity
Asera_12510	COG1846	Transcriptional regulator
Asera_12540	COG1132	(ABC) transporter
Asera_12550	COG3559	Exporter of polyketide antibiotics
Asera_12560	COG1131	(ABC) transporter
Asera_12580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_12600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_12610	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Asera_12730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Asera_12790	COG2026	Addiction module toxin, RelE StbE family
Asera_12800	COG0438	transferase activity, transferring glycosyl groups
Asera_12810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_12830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Asera_12850	COG1316	TRANSCRIPTIONal
Asera_12860	COG1316	TRANSCRIPTIONal
Asera_12880	COG5002	protein histidine kinase activity
Asera_12910	COG0604	alcohol dehydrogenase
Asera_12940	COG2837	iron assimilation
Asera_12960	COG0672	)-iron permease
Asera_13010	COG1234	tRNA 3'-trailer cleavage
Asera_13020	COG4991	sh3 domain protein
Asera_13100	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Asera_13130	COG2226	methyltransferase
Asera_13190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Asera_13220	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Asera_13230	COG0583	DNA-binding transcription factor activity
Asera_13270	COG0584	glycerophosphoryl diester phosphodiesterase
Asera_13290	COG1021	2,3-dihydroxybenzoate-AMP ligase
Asera_13300	COG0189	ligase activity
Asera_13370	COG0205	6-phosphofructokinase activity
Asera_13390	COG1733	regulation of RNA biosynthetic process
Asera_13410	COG1846	Transcriptional regulator
Asera_13420	COG0546	phosphoglycolate phosphatase activity
Asera_13450	COG4585	Histidine kinase
Asera_13460	COG2197	response regulator
Asera_13510	COG2197	response regulator
Asera_13520	COG4585	Histidine kinase
Asera_13550	COG0789	Transcriptional regulator
Asera_13560	COG3959	Transketolase, thiamine diphosphate binding domain
Asera_13570	COG3958	Transketolase
Asera_13670	COG0561	phosphatase activity
Asera_13700	COG0561	phosphatase activity
Asera_13710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Asera_13720	COG1764	response to oxidative stress
Asera_13780	COG0745	RESPONSE REGULATOR receiver
Asera_13800	COG0500	methyltransferase
Asera_13810	COG0588	phosphoglycerate mutase activity
Asera_13830	COG1414	Transcriptional regulator
Asera_13870	COG4106	trans-aconitate 2-methyltransferase activity
Asera_13900	COG1691	(AIR) carboxylase
Asera_13910	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Asera_13920	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Asera_14010	COG2205	protein histidine kinase activity
Asera_14020	COG0745	RESPONSE REGULATOR receiver
Asera_14050	COG0577	efflux transmembrane transporter activity
Asera_14050	COG1136	(ABC) transporter
Asera_14060	COG0577	efflux transmembrane transporter activity
Asera_14070	COG0702	epimerase
Asera_14110	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Asera_14140	COG0640	Transcriptional regulator
Asera_14150	COG0583	DNA-binding transcription factor activity
Asera_14220	COG0640	Transcriptional regulator
Asera_14240	COG0640	Transcriptional regulator
Asera_14250	COG2072	flavoprotein involved in K transport
Asera_14270	COG2072	flavoprotein involved in K transport
Asera_14290	COG0798	PFAM Bile acid sodium symporter
Asera_14300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Asera_14340	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_14350	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_14400	COG1280	lysine exporter protein (LysE YggA)
Asera_14420	COG0110	maltose O-acetyltransferase activity
Asera_14430	COG1309	transcriptional regulator
Asera_14520	COG0384	phenazine biosynthesis protein PhzF
Asera_14570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Asera_14610	COG0640	Transcriptional regulator
Asera_14670	COG1376	ErfK ybiS ycfS ynhG family protein
Asera_14750	COG4941	Belongs to the sigma-70 factor family
Asera_14770	COG2197	response regulator
Asera_14800	COG1136	(ABC) transporter
Asera_14810	COG0110	maltose O-acetyltransferase activity
Asera_14900	COG2197	response regulator
Asera_14920	COG2814	Major facilitator Superfamily
Asera_15110	COG1846	Transcriptional regulator
Asera_15110	COG1940	carbohydrate kinase activity
Asera_15150	COG2318	DinB family
Asera_15170	COG1473	amidohydrolase
Asera_15180	COG0477	Major facilitator Superfamily
Asera_15200	COG2814	Major facilitator Superfamily
Asera_15220	COG1120	ATPase activity
Asera_15300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Asera_15310	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Asera_15320	COG1414	Transcriptional regulator
Asera_15340	COG0800	Aldolase
Asera_15370	COG1609	Transcriptional regulator
Asera_15400	COG0747	negative chemotaxis
Asera_15410	COG4166	transmembrane transport
Asera_15430	COG0406	alpha-ribazole phosphatase activity
Asera_15460	COG0601	transmembrane transport
Asera_15470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_15490	COG4608	Belongs to the ABC transporter superfamily
Asera_15560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_15570	COG0765	amino acid transport
Asera_15580	COG0765	amino acid transport
Asera_15590	COG1126	abc transporter atp-binding protein
Asera_15610	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_15620	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_15630	COG2186	Transcriptional regulator
Asera_15640	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_15670	COG0395	ABC-type sugar transport system, permease component
Asera_15700	COG0477	Major facilitator Superfamily
Asera_15730	COG1902	pentaerythritol trinitrate reductase activity
Asera_15740	COG2936	dipeptidyl-peptidase activity
Asera_15770	COG1796	DNA polymerase
Asera_15770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Asera_15780	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Asera_15780	COG0235	Class ii aldolase
Asera_15790	COG0287	Prephenate dehydrogenase
Asera_15850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Asera_15860	COG0813	purine-nucleoside phosphorylase activity
Asera_15870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_15940	COG1562	ergosterol biosynthetic process
Asera_15960	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Asera_16180	COG0789	Transcriptional regulator
Asera_16220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_16240	COG0789	Transcriptional regulator
Asera_16290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Asera_16300	COG0693	protein deglycase activity
Asera_16340	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Asera_16350	COG0583	DNA-binding transcription factor activity
Asera_16430	COG0477	Major facilitator Superfamily
Asera_16440	COG0443	Heat shock 70 kDa protein
Asera_16450	COG0776	regulation of translation
Asera_16480	COG2814	Major facilitator Superfamily
Asera_16530	COG1131	(ABC) transporter
Asera_16540	COG4585	Histidine kinase
Asera_16550	COG2197	response regulator
Asera_16560	COG1309	transcriptional regulator
Asera_16570	COG0477	Major facilitator Superfamily
Asera_16580	COG0583	DNA-binding transcription factor activity
Asera_16590	COG0300	oxidoreductase activity
Asera_16630	COG1309	transcriptional regulator
Asera_16640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asera_16700	COG1309	transcriptional regulator
Asera_16710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Asera_16740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Asera_16880	COG0003	Pfam Anion-transporting ATPase
Asera_16900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_16920	COG1408	metallophosphoesterase
Asera_17120	COG0583	DNA-binding transcription factor activity
Asera_17170	COG0183	Belongs to the thiolase family
Asera_17210	COG0477	Major facilitator Superfamily
Asera_17240	COG1595	DNA-templated transcription, initiation
Asera_17280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_17320	COG1674	ftsk spoiiie
Asera_17390	COG3706	GGDEF domain
Asera_17400	COG1716	ATPase activity
Asera_17420	COG0745	RESPONSE REGULATOR receiver
Asera_17430	COG2205	protein histidine kinase activity
Asera_17440	COG2197	response regulator
Asera_17450	COG2203	Gaf domain
Asera_17450	COG4585	Histidine kinase
Asera_17460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Asera_17480	COG3145	DNA-N1-methyladenine dioxygenase activity
Asera_17550	COG2378	regulation of single-species biofilm formation
Asera_17600	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Asera_17610	COG0477	Major facilitator Superfamily
Asera_17620	COG4585	Histidine kinase
Asera_17630	COG2188	Transcriptional regulator
Asera_17670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_17700	COG0247	lactate metabolic process
Asera_17710	COG0277	FAD linked oxidase domain protein
Asera_17720	COG0277	FAD linked oxidase domain protein
Asera_17730	COG0702	epimerase
Asera_17780	COG2205	protein histidine kinase activity
Asera_17780	COG2198	Histidine kinase
Asera_17780	COG0784	Response regulator, receiver
Asera_17810	COG0671	phosphoesterase, PA-phosphatase related
Asera_17840	COG1404	Belongs to the peptidase S8 family
Asera_17930	COG2267	carboxylic ester hydrolase activity
Asera_17940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asera_17950	COG2197	response regulator
Asera_17970	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Asera_17980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Asera_17990	COG0181	hydroxymethylbilane synthase activity
Asera_18000	COG1648	precorrin-2 dehydrogenase activity
Asera_18000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Asera_18010	COG0113	porphobilinogen synthase activity
Asera_18040	COG3328	transposase activity
Asera_18080	COG0765	amino acid transport
Asera_18090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_18120	COG3469	chitinase activity
Asera_18150	COG4941	Belongs to the sigma-70 factor family
Asera_18160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_18220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Asera_18230	COG0406	alpha-ribazole phosphatase activity
Asera_18240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asera_18250	COG0785	Cytochrome C biogenesis protein
Asera_18260	COG1333	cytochrome c biogenesis protein
Asera_18270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Asera_18320	COG3896	Chloramphenicol phosphotransferase-like protein
Asera_18360	COG0438	transferase activity, transferring glycosyl groups
Asera_18430	COG0745	RESPONSE REGULATOR receiver
Asera_18440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Asera_18470	COG1082	Xylose isomerase domain protein TIM barrel
Asera_18510	COG1175	transmembrane transport
Asera_18520	COG0395	ABC-type sugar transport system, permease component
Asera_18580	COG4585	Histidine kinase
Asera_18620	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Asera_18630	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Asera_18640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Asera_18660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Asera_18680	COG0583	DNA-binding transcription factor activity
Asera_18690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Asera_18730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Asera_18770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Asera_18780	COG1194	a g-specific adenine glycosylase
Asera_18800	COG1595	DNA-templated transcription, initiation
Asera_18830	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Asera_18840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Asera_18870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asera_18920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Asera_18930	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Asera_18990	COG4290	ribonuclease
Asera_19020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asera_19040	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Asera_19050	COG1522	sequence-specific DNA binding
Asera_19070	COG3654	unkown
Asera_19090	COG0542	response to heat
Asera_19160	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Asera_19220	COG2186	Transcriptional regulator
Asera_19270	COG0405	Gamma-glutamyltransferase
Asera_19300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_19330	COG1802	Transcriptional regulator
Asera_19350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asera_19360	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Asera_19380	COG1252	NADH dehydrogenase
Asera_19390	COG3973	AAA domain
Asera_19410	COG1051	belongs to the nudix hydrolase family
Asera_19450	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Asera_19490	COG3396	Phenylacetate-CoA oxygenase
Asera_19500	COG3460	Phenylacetate-CoA oxygenase
Asera_19510	COG3396	Phenylacetate-CoA oxygenase
Asera_19520	COG2151	metal-sulfur cluster biosynthetic enzyme
Asera_19530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asera_19550	COG1022	Amp-dependent synthetase and ligase
Asera_19570	COG2050	protein possibly involved in aromatic compounds catabolism
Asera_19620	COG0644	oxidoreductase
Asera_19630	COG3396	Phenylacetate-CoA oxygenase
Asera_19640	COG2022	thiamine diphosphate biosynthetic process
Asera_19640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asera_19690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Asera_19700	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Asera_19750	COG2226	methyltransferase
Asera_19780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_19790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_19800	COG0649	NAD binding
Asera_19820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Asera_19830	COG1034	ATP synthesis coupled electron transport
Asera_19840	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Asera_19850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_19870	COG0713	ATP synthesis coupled electron transport
Asera_19900	COG1007	ATP synthesis coupled electron transport
Asera_19910	COG0142	geranyltranstransferase activity
Asera_19950	COG1404	Belongs to the peptidase S8 family
Asera_20010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Asera_20020	COG1950	PFAM Membrane protein of
Asera_20040	COG1309	transcriptional regulator
Asera_20060	COG1013	pyruvate-flavodoxin oxidoreductase activity
Asera_20070	COG0674	pyruvate-flavodoxin oxidoreductase activity
Asera_20070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Asera_20120	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_20130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_20140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_20150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Asera_20180	COG0667	Aldo Keto reductase
Asera_20190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_20210	COG0839	Belongs to the complex I subunit 6 family
Asera_20220	COG0713	ATP synthesis coupled electron transport
Asera_20230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Asera_20250	COG1007	ATP synthesis coupled electron transport
Asera_20260	COG0501	Belongs to the peptidase M48B family
Asera_20280	COG2267	carboxylic ester hydrolase activity
Asera_20290	COG2315	Protein conserved in bacteria
Asera_20300	COG1666	GTP binding
Asera_20770	COG3300	MHYT domain
Asera_20770	COG5001	Diguanylate cyclase
Asera_20780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Asera_20790	COG2030	dehydratase
Asera_20810	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Asera_20830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Asera_20840	COG0081	regulation of translation
Asera_20850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Asera_20860	COG0222	ribosome binding
Asera_20870	COG1127	ABC transporter
Asera_20880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Asera_20890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Asera_20940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Asera_20980	COG0085	RNA polymerase activity
Asera_20990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Asera_21020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Asera_21030	COG0049	tRNA binding
Asera_21040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Asera_21050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Asera_21060	COG0051	transcription antitermination factor activity, RNA binding
Asera_21070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Asera_21080	COG0088	Forms part of the polypeptide exit tunnel
Asera_21090	COG0089	rRNA binding
Asera_21100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Asera_21110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Asera_21120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Asera_21130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Asera_21140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Asera_21150	COG0255	Belongs to the universal ribosomal protein uL29 family
Asera_21160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Asera_21170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Asera_21180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Asera_21190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Asera_21200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Asera_21210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Asera_21220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Asera_21230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Asera_21240	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Asera_21250	COG1841	ribosomal large subunit assembly
Asera_21260	COG0200	Binds to the 23S rRNA
Asera_21280	COG0563	adenylate kinase activity
Asera_21310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Asera_21320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Asera_21330	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Asera_21340	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Asera_21350	COG0202	RNA polymerase activity
Asera_21360	COG0203	ribosomal protein L17
Asera_21370	COG0101	tRNA pseudouridine synthase activity
Asera_21440	COG0488	(ABC) transporter
Asera_21470	COG2814	Major facilitator Superfamily
Asera_21480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Asera_21490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Asera_21500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asera_21520	COG0583	DNA-binding transcription factor activity
Asera_21550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asera_21570	COG4977	sequence-specific DNA binding
Asera_21580	COG4115	mRNA cleavage
Asera_21590	COG2161	toxin-antitoxin pair type II binding
Asera_21600	COG0667	Aldo Keto reductase
Asera_21610	COG0443	Heat shock 70 kDa protein
Asera_21620	COG1505	serine-type exopeptidase activity
Asera_21630	COG0736	holo-[acyl-carrier-protein] synthase activity
Asera_21650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Asera_21670	COG0802	atpase or kinase
Asera_21680	COG2267	carboxylic ester hydrolase activity
Asera_21690	COG0456	acetyltransferase
Asera_21690	COG1214	PFAM Peptidase M22, glycoprotease
Asera_21710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Asera_21720	COG4585	Histidine kinase
Asera_21730	COG2197	response regulator
Asera_21780	COG1132	(ABC) transporter
Asera_21790	COG1132	(ABC) transporter
Asera_21810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_21820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Asera_21860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Asera_21870	COG0459	protein refolding
Asera_21900	COG2197	response regulator
Asera_21960	COG0516	GMP reductase activity
Asera_21980	COG0531	amino acid
Asera_22070	COG1175	transmembrane transport
Asera_22090	COG0395	ABC-type sugar transport system, permease component
Asera_22150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Asera_22150	COG0519	Catalyzes the synthesis of GMP from XMP
Asera_22170	COG1056	cytidyltransferase-related domain
Asera_22170	COG1051	belongs to the nudix hydrolase family
Asera_22180	COG1183	phosphatidylcholine synthase activity
Asera_22190	COG2197	response regulator
Asera_22240	COG0688	phosphatidylethanolamine metabolic process
Asera_22270	COG4585	Histidine kinase
Asera_22280	COG2197	response regulator
Asera_22310	COG1605	Chorismate mutase
Asera_22360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Asera_22390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_22410	COG0045	succinate-CoA ligase (ADP-forming) activity
Asera_22480	COG0138	bifunctional purine biosynthesis protein purh
Asera_22490	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_22500	COG1733	regulation of RNA biosynthetic process
Asera_22550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asera_22620	COG1175	transmembrane transport
Asera_22630	COG0395	ABC-type sugar transport system, permease component
Asera_22660	COG1569	PIN domain
Asera_22670	COG3311	Transcriptional regulator
Asera_22680	COG0477	Major facilitator Superfamily
Asera_22720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Asera_22770	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Asera_22780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Asera_22800	COG1349	DNA-binding transcription factor activity
Asera_22820	COG1175	transmembrane transport
Asera_22830	COG0395	ABC-type sugar transport system, permease component
Asera_22840	COG0180	Tryptophanyl-tRNA synthetase
Asera_22860	COG1309	transcriptional regulator
Asera_22890	COG1744	ABC transporter substrate-binding protein PnrA-like
Asera_22900	COG3845	ABC transporter
Asera_22910	COG4603	Belongs to the binding-protein-dependent transport system permease family
Asera_22920	COG1079	Belongs to the binding-protein-dependent transport system permease family
Asera_22950	COG0542	response to heat
Asera_22960	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Asera_22960	COG0662	Cupin 2, conserved barrel domain protein
Asera_22990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_23140	COG2018	Roadblock/LC7 domain
Asera_23200	COG4166	transmembrane transport
Asera_23220	COG4166	transmembrane transport
Asera_23270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_23330	COG2171	N-acyltransferase activity
Asera_23390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asera_23400	COG1611	Belongs to the LOG family
Asera_23420	COG0702	epimerase
Asera_23450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Asera_23470	COG0519	Catalyzes the synthesis of GMP from XMP
Asera_23490	COG1024	Enoyl-CoA hydratase
Asera_23520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Asera_23530	COG0657	acetylesterase activity
Asera_23560	COG2197	response regulator
Asera_23610	COG0297	glycogen (starch) synthase activity
Asera_23680	COG1657	PFAM Prenyltransferase squalene oxidase
Asera_23700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Asera_23720	COG1562	ergosterol biosynthetic process
Asera_23730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Asera_23740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Asera_23800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Asera_23820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Asera_23880	COG3480	Lon protease (S16) C-terminal proteolytic domain
Asera_23890	COG1615	UPF0182 protein
Asera_23970	COG2186	Transcriptional regulator
Asera_24000	COG2226	methyltransferase
Asera_24040	COG0154	amidase activity
Asera_24070	COG2226	methyltransferase
Asera_24140	COG0488	(ABC) transporter
Asera_24160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asera_24190	COG4585	Histidine kinase
Asera_24200	COG2197	response regulator
Asera_24240	COG2226	methyltransferase
Asera_24270	COG1653	transport
Asera_24290	COG1175	transmembrane transport
Asera_24340	COG1695	Transcriptional regulator
Asera_24430	COG1742	UPF0060 membrane protein
Asera_24450	COG3345	alpha-galactosidase
Asera_24470	COG0424	maF-like protein
Asera_24580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Asera_24590	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_24590	COG3848	Pyruvate phosphate dikinase
Asera_24630	COG1302	Protein conserved in bacteria
Asera_24680	COG0483	inositol monophosphate 1-phosphatase activity
Asera_24760	COG1832	CoA-binding protein
Asera_24770	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Asera_24810	COG1216	Glycosyl transferase, family 2
Asera_24830	COG2267	carboxylic ester hydrolase activity
Asera_24890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_24910	COG2267	carboxylic ester hydrolase activity
Asera_24950	COG0438	transferase activity, transferring glycosyl groups
Asera_24970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_25010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Asera_25070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asera_25080	COG2835	tetraacyldisaccharide 4'-kinase activity
Asera_25110	COG1482	cell wall glycoprotein biosynthetic process
Asera_25150	COG2124	cytochrome p450
Asera_25240	COG1309	transcriptional regulator
Asera_25260	COG4585	Histidine kinase
Asera_25270	COG0586	Pfam SNARE associated Golgi protein
Asera_25320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Asera_25330	COG1595	DNA-templated transcription, initiation
Asera_25340	COG1595	DNA-templated transcription, initiation
Asera_25420	COG3973	AAA domain
Asera_25480	COG2197	response regulator
Asera_25490	COG4941	Belongs to the sigma-70 factor family
Asera_25500	COG3795	YCII-related domain
Asera_25650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Asera_25690	COG1053	succinate dehydrogenase
Asera_25730	COG1595	DNA-templated transcription, initiation
Asera_25810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Asera_25830	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asera_25860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_25870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_25890	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Asera_25950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_26030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asera_26030	COG1017	nitric oxide dioxygenase activity
Asera_26060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Asera_26110	COG0596	Alpha beta hydrolase
Asera_26140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asera_26170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asera_26200	COG0640	Transcriptional regulator
Asera_26300	COG3321	synthase
Asera_26300	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_26300	COG0604	alcohol dehydrogenase
Asera_26320	COG0531	amino acid
Asera_26340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Asera_26470	COG3254	rhamnose metabolic process
Asera_26540	COG0071	Belongs to the small heat shock protein (HSP20) family
Asera_26720	COG4821	SIS domain
Asera_26770	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_26810	COG3655	Transcriptional regulator
Asera_26820	COG1309	transcriptional regulator
Asera_26830	COG0604	alcohol dehydrogenase
Asera_26830	COG3321	synthase
Asera_26830	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_26870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asera_26870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_26970	COG0789	Transcriptional regulator
Asera_26980	COG0604	alcohol dehydrogenase
Asera_27020	COG1131	(ABC) transporter
Asera_27080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asera_27140	COG0346	lactoylglutathione lyase activity
Asera_27160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asera_27170	COG0129	dihydroxy-acid dehydratase activity
Asera_27180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Asera_27190	COG3387	PFAM Glycoside hydrolase 15-related
Asera_27210	COG1609	Transcriptional regulator
Asera_27230	COG1733	regulation of RNA biosynthetic process
Asera_27240	COG0604	alcohol dehydrogenase
Asera_27240	COG3321	synthase
Asera_27260	COG1522	sequence-specific DNA binding
Asera_27300	COG1122	ATPase activity
Asera_27310	COG1725	Transcriptional regulator
Asera_27410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asera_27430	COG0154	amidase activity
Asera_27450	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_27490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asera_27500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Asera_27510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asera_27530	COG0783	Belongs to the Dps family
Asera_27540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asera_27540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asera_27610	COG0583	DNA-binding transcription factor activity
Asera_27650	COG1233	COG1233 Phytoene dehydrogenase and related
Asera_27670	COG0142	geranyltranstransferase activity
Asera_27780	COG0431	NADPH-dependent FMN reductase
Asera_27790	COG0477	Major facilitator Superfamily
Asera_27800	COG0789	Transcriptional regulator
Asera_27820	COG2267	carboxylic ester hydrolase activity
Asera_27840	COG0477	Major facilitator Superfamily
Asera_27880	COG0549	Belongs to the carbamate kinase family
Asera_27920	COG1063	alcohol dehydrogenase
Asera_28000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Asera_28120	COG2409	Drug exporters of the RND superfamily
Asera_28170	COG0477	Major facilitator Superfamily
Asera_28350	COG0739	heme binding
Asera_28390	COG2272	Belongs to the type-B carboxylesterase lipase family
Asera_28410	COG2318	DinB family
Asera_28420	COG2814	Major facilitator Superfamily
Asera_28430	COG0402	S-adenosylhomocysteine deaminase activity
Asera_28500	COG1802	Transcriptional regulator
Asera_28510	COG0667	Aldo Keto reductase
Asera_28530	COG0456	acetyltransferase
Asera_28660	COG0583	DNA-binding transcription factor activity
Asera_28680	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_28720	COG1733	regulation of RNA biosynthetic process
Asera_28790	COG0583	DNA-binding transcription factor activity
Asera_28870	COG1280	lysine exporter protein (LysE YggA)
Asera_28900	COG2353	YceI-like domain
Asera_28910	COG1335	isochorismatase
Asera_28940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Asera_28960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_29100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_29140	COG1309	transcriptional regulator
Asera_29150	COG1063	alcohol dehydrogenase
Asera_29170	COG2814	Major facilitator Superfamily
Asera_29240	COG2304	oxidoreductase activity
Asera_29340	COG1278	Cold shock
Asera_29350	COG1505	serine-type exopeptidase activity
Asera_29370	COG1228	amidohydrolase
Asera_29430	COG1063	alcohol dehydrogenase
Asera_29450	COG2508	Transcriptional regulator
Asera_29450	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Asera_29470	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_29520	COG0444	Belongs to the ABC transporter superfamily
Asera_29570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asera_29640	COG2211	Major facilitator Superfamily
Asera_29650	COG0076	glutamate decarboxylase activity
Asera_29840	COG0612	Peptidase, M16
Asera_29990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Asera_30010	COG1846	Transcriptional regulator
Asera_30140	COG3387	PFAM Glycoside hydrolase 15-related
Asera_30150	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_30170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_30200	COG1846	Transcriptional regulator
Asera_30200	COG1940	carbohydrate kinase activity
Asera_30250	COG1940	carbohydrate kinase activity
Asera_30250	COG1846	Transcriptional regulator
Asera_30270	COG1940	carbohydrate kinase activity
Asera_30280	COG1653	transport
Asera_30290	COG1175	transmembrane transport
Asera_30300	COG0395	ABC-type sugar transport system, permease component
Asera_30320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Asera_30390	COG0483	inositol monophosphate 1-phosphatase activity
Asera_30430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Asera_30470	COG1595	DNA-templated transcription, initiation
Asera_30480	COG5662	AntiSigma factor
Asera_30500	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Asera_30510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asera_30520	COG1174	glycine betaine transport
Asera_30540	COG1174	glycine betaine transport
Asera_30570	COG3384	dioxygenase
Asera_30620	COG0667	Aldo Keto reductase
Asera_30640	COG1309	transcriptional regulator
Asera_30660	COG0542	response to heat
Asera_30700	COG0175	sulfate reduction
Asera_30730	COG1597	lipid kinase activity
Asera_30760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Asera_30770	COG1335	isochorismatase
Asera_30780	COG0740	serine-type endopeptidase activity
Asera_30790	COG0740	serine-type endopeptidase activity
Asera_30800	COG1396	sequence-specific DNA binding
Asera_30810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Asera_30840	COG0697	spore germination
Asera_30850	COG0300	oxidoreductase activity
Asera_30870	COG0737	Belongs to the 5'-nucleotidase family
Asera_31070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_31080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asera_31150	COG2239	Acts as a magnesium transporter
Asera_31190	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_31310	COG0613	PHP domain protein
Asera_31320	COG2095	MarC family integral membrane protein
Asera_31380	COG1309	transcriptional regulator
Asera_31390	COG0702	epimerase
Asera_31430	COG0513	Belongs to the DEAD box helicase family
Asera_31520	COG1366	Belongs to the anti-sigma-factor antagonist family
Asera_31530	COG0583	DNA-binding transcription factor activity
Asera_31560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Asera_31570	COG1609	Transcriptional regulator
Asera_31620	COG0395	ABC-type sugar transport system, permease component
Asera_31660	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Asera_31690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Asera_31720	COG2337	Toxic component of a toxin-antitoxin (TA) module
Asera_31740	COG2223	nitrite transmembrane transporter activity
Asera_31750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Asera_31770	COG4221	oxidoreductase activity
Asera_31800	COG0583	DNA-binding transcription factor activity
Asera_31810	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Asera_31830	COG0366	Alpha amylase catalytic
Asera_31860	COG0668	transmembrane transport
Asera_31920	COG0154	amidase activity
Asera_31940	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Asera_31960	COG1733	regulation of RNA biosynthetic process
Asera_31990	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asera_32050	COG1136	(ABC) transporter
Asera_32110	COG1051	belongs to the nudix hydrolase family
Asera_32160	COG1530	ribonuclease E activity
Asera_32170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Asera_32180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Asera_32190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Asera_32250	COG0747	negative chemotaxis
Asera_32260	COG0601	transmembrane transport
Asera_32270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_32280	COG0444	Belongs to the ABC transporter superfamily
Asera_32290	COG4608	Belongs to the ABC transporter superfamily
Asera_32320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asera_32330	COG1929	Belongs to the glycerate kinase type-1 family
Asera_32350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_32360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Asera_32400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Asera_32500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Asera_32510	COG1051	belongs to the nudix hydrolase family
Asera_32520	COG1595	DNA-templated transcription, initiation
Asera_32530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Asera_32550	COG2124	cytochrome p450
Asera_32570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asera_32610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_32620	COG0501	Belongs to the peptidase M48B family
Asera_32630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Asera_32630	COG2755	lipolytic protein G-D-S-L family
Asera_32640	COG0438	transferase activity, transferring glycosyl groups
Asera_32740	COG1940	carbohydrate kinase activity
Asera_32770	COG0583	DNA-binding transcription factor activity
Asera_32780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asera_32840	COG0156	8-amino-7-oxononanoate synthase activity
Asera_32850	COG1063	alcohol dehydrogenase
Asera_32860	COG0028	Belongs to the TPP enzyme family
Asera_32920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_32950	COG2072	flavoprotein involved in K transport
Asera_33030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asera_33070	COG0205	6-phosphofructokinase activity
Asera_33090	COG4175	Glycine betaine
Asera_33090	COG0517	IMP dehydrogenase activity
Asera_33120	COG1309	transcriptional regulator
Asera_33130	COG0477	Major facilitator Superfamily
Asera_33140	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Asera_33150	COG3511	phospholipase C
Asera_33170	COG3511	phospholipase C
Asera_33210	COG0667	Aldo Keto reductase
Asera_33230	COG1733	regulation of RNA biosynthetic process
Asera_33240	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Asera_33250	COG0515	serine threonine protein kinase
Asera_33250	COG2815	serine threonine protein kinase
Asera_33260	COG2226	methyltransferase
Asera_33320	COG1609	Transcriptional regulator
Asera_33340	COG1196	nuclear chromosome segregation
Asera_33360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Asera_33370	COG3537	Alpha-1,2-mannosidase
Asera_33380	COG0252	asparaginase activity
Asera_33400	COG1104	cysteine desulfurase activity
Asera_33410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Asera_33450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Asera_33470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Asera_33490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Asera_33500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Asera_33520	COG0789	Transcriptional regulator
Asera_33560	COG0737	Belongs to the 5'-nucleotidase family
Asera_33580	COG0745	RESPONSE REGULATOR receiver
Asera_33590	COG5002	protein histidine kinase activity
Asera_33600	COG2358	TRAP transporter, solute receptor (TAXI family
Asera_33630	COG1643	Atp-dependent helicase
Asera_33670	COG4221	oxidoreductase activity
Asera_33690	COG2072	flavoprotein involved in K transport
Asera_33730	COG0183	Belongs to the thiolase family
Asera_33740	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_33760	COG1309	transcriptional regulator
Asera_33780	COG1960	acyl-CoA dehydrogenase activity
Asera_33820	COG1309	transcriptional regulator
Asera_33830	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_33870	COG3552	Protein containing von Willebrand factor type A (VWA) domain
Asera_33880	COG0714	Associated with various cellular activities
Asera_33930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_33980	COG3629	intracellular signal transduction
Asera_33980	COG3903	Transcriptional regulator
Asera_34000	COG0142	geranyltranstransferase activity
Asera_34080	COG0583	DNA-binding transcription factor activity
Asera_34130	COG0137	argininosuccinate synthase activity
Asera_34150	COG5434	Belongs to the glycosyl hydrolase 28 family
Asera_34150	COG4632	Exopolysaccharide biosynthesis protein
Asera_34160	COG3959	Transketolase, thiamine diphosphate binding domain
Asera_34180	COG1937	Protein conserved in bacteria
Asera_34210	COG1122	ATPase activity
Asera_34220	COG4721	ABC-type cobalt transport system, permease component
Asera_34320	COG0423	glycine-tRNA ligase activity
Asera_34410	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_34410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asera_34470	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Asera_34520	COG0277	FAD linked oxidase domain protein
Asera_34520	COG0247	lactate metabolic process
Asera_34590	COG1132	(ABC) transporter
Asera_34600	COG1846	Transcriptional regulator
Asera_34610	COG0358	DNA primase activity
Asera_34640	COG1131	(ABC) transporter
Asera_34740	COG0667	Aldo Keto reductase
Asera_34820	COG1595	DNA-templated transcription, initiation
Asera_34850	COG3938	Belongs to the proline racemase family
Asera_34860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asera_34910	COG0018	arginyl-trna synthetase
Asera_34960	COG1846	Transcriptional regulator
Asera_34970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_34970	COG3321	synthase
Asera_34970	COG0604	alcohol dehydrogenase
Asera_34970	COG4221	oxidoreductase activity
Asera_35010	COG0714	Associated with various cellular activities
Asera_35080	COG0302	gtp cyclohydrolase
Asera_35170	COG2205	protein histidine kinase activity
Asera_35240	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_35250	COG1920	GTP binding
Asera_35270	COG3345	alpha-galactosidase
Asera_35320	COG1121	(ABC) transporter
Asera_35360	COG1199	ATP-dependent helicase activity
Asera_35360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Asera_35380	COG1116	anion transmembrane transporter activity
Asera_35490	COG3328	transposase activity
Asera_35510	COG3328	transposase activity
Asera_35570	COG4974	Belongs to the 'phage' integrase family
Asera_35670	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Asera_35680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Asera_35710	COG0642	Histidine kinase
Asera_35770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Asera_35780	COG2814	Major facilitator Superfamily
Asera_35800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Asera_35810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Asera_35810	COG2755	lipolytic protein G-D-S-L family
Asera_35850	COG2837	iron assimilation
Asera_35940	COG0477	Major facilitator Superfamily
Asera_35980	COG0395	ABC-type sugar transport system, permease component
Asera_35990	COG1175	transmembrane transport
Asera_36040	COG4122	O-methyltransferase activity
Asera_36050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Asera_36050	COG0512	Glutamine amidotransferase of anthranilate synthase
Asera_36060	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_36130	COG0697	spore germination
Asera_36140	COG1846	Transcriptional regulator
Asera_36170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Asera_36190	COG0017	Asparaginyl-tRNA synthetase
Asera_36200	COG0321	lipoyl(octanoyl) transferase activity
Asera_36220	COG1134	teichoic acid transport
Asera_36250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Asera_36260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Asera_36280	COG0384	phenazine biosynthesis protein PhzF
Asera_36290	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_36300	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_36310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asera_36340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Asera_36370	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Asera_36380	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Asera_36400	COG0667	Aldo Keto reductase
Asera_36420	COG1609	Transcriptional regulator
Asera_36470	COG3119	arylsulfatase activity
Asera_36510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asera_36520	COG0586	Pfam SNARE associated Golgi protein
Asera_36590	COG0740	serine-type endopeptidase activity
Asera_36630	COG1063	alcohol dehydrogenase
Asera_36660	COG0542	response to heat
Asera_36680	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Asera_36710	COG1573	uracil-dna glycosylase
Asera_36720	COG1620	l-lactate permease
Asera_36770	COG1609	Transcriptional regulator
Asera_36790	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_36800	COG2271	Major facilitator Superfamily
Asera_36810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_36820	COG1024	Enoyl-CoA hydratase
Asera_36850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Asera_36980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_37130	COG4974	Belongs to the 'phage' integrase family
Asera_37340	COG0582	viral genome integration into host DNA
Asera_37410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_37540	COG0582	viral genome integration into host DNA
Asera_37610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_37740	COG0582	viral genome integration into host DNA
Asera_37810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_37940	COG0582	viral genome integration into host DNA
Asera_37960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_37980	COG2314	TM2 domain
Asera_38000	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_38020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Asera_38030	COG1414	Transcriptional regulator
Asera_38070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Asera_38090	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Asera_38100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Asera_38100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Asera_38110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Asera_38120	COG0174	glutamine synthetase
Asera_38140	COG0442	prolyl-tRNA aminoacylation
Asera_38190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Asera_38210	COG0277	FAD linked oxidase domain protein
Asera_38220	COG0247	lactate metabolic process
Asera_38230	COG2321	neutral zinc metallopeptidase
Asera_38250	COG1757	Na H antiporter
Asera_38270	COG2235	arginine
Asera_38300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Asera_38310	COG3469	chitinase activity
Asera_38350	COG0410	ABC transporter
Asera_38410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asera_38480	COG0776	regulation of translation
Asera_38490	COG1741	Belongs to the pirin family
Asera_38590	COG3189	MarR family transcriptional regulator
Asera_38600	COG3876	Protein conserved in bacteria
Asera_38610	COG1737	Transcriptional regulator
Asera_38630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_38660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Asera_38720	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Asera_38720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Asera_38740	COG0018	arginyl-trna synthetase
Asera_38750	COG0019	diaminopimelate decarboxylase activity
Asera_38760	COG0460	homoserine dehydrogenase
Asera_38770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Asera_38810	COG0745	RESPONSE REGULATOR receiver
Asera_38820	COG2205	protein histidine kinase activity
Asera_38840	COG0083	homoserine kinase activity
Asera_38860	COG5006	permease, DMT superfamily
Asera_38870	COG1063	alcohol dehydrogenase
Asera_38910	COG0254	rRNA binding
Asera_38920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Asera_38940	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_38950	COG0009	L-threonylcarbamoyladenylate synthase
Asera_38990	COG0356	it plays a direct role in the translocation of protons across the membrane
Asera_39000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Asera_39010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Asera_39020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Asera_39030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Asera_39040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Asera_39050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Asera_39060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Asera_39100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asera_39160	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_39180	COG3285	dna ligase
Asera_39180	COG1793	dna ligase
Asera_39220	COG1674	ftsk spoiiie
Asera_39380	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Asera_39470	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_39480	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_39530	COG2267	carboxylic ester hydrolase activity
Asera_39540	COG2267	carboxylic ester hydrolase activity
Asera_39550	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_39570	COG0123	including yeast histone deacetylase and acetoin utilization protein
Asera_39620	COG0501	Belongs to the peptidase M48B family
Asera_39630	COG1490	D-aminoacyl-tRNA deacylase activity
Asera_39640	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_39660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_39670	COG2313	pseudouridylate synthase activity
Asera_39730	COG0483	inositol monophosphate 1-phosphatase activity
Asera_39780	COG0756	dUTP diphosphatase activity
Asera_39840	COG0569	domain protein
Asera_39850	COG0531	amino acid
Asera_39860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Asera_39870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Asera_39900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asera_39910	COG1940	carbohydrate kinase activity
Asera_39920	COG4213	ABC transporter substrate-binding protein
Asera_39940	COG4214	carbohydrate transport
Asera_39950	COG4608	Belongs to the ABC transporter superfamily
Asera_39960	COG0444	Belongs to the ABC transporter superfamily
Asera_39970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_39980	COG0601	transmembrane transport
Asera_39990	COG0747	negative chemotaxis
Asera_40000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_40010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Asera_40020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Asera_40050	COG3537	Alpha-1,2-mannosidase
Asera_40100	COG0745	RESPONSE REGULATOR receiver
Asera_40110	COG2205	protein histidine kinase activity
Asera_40180	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_40180	COG3321	synthase
Asera_40180	COG0604	alcohol dehydrogenase
Asera_40190	COG1309	transcriptional regulator
Asera_40200	COG0477	Major facilitator Superfamily
Asera_40250	COG1024	Enoyl-CoA hydratase
Asera_40250	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_40260	COG0183	Belongs to the thiolase family
Asera_40270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Asera_40280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_40320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Asera_40330	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Asera_40340	COG3253	May function as heme-dependent peroxidase
Asera_40360	COG1940	carbohydrate kinase activity
Asera_40390	COG3579	cysteine-type endopeptidase activity
Asera_40430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asera_40460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Asera_40480	COG3962	Belongs to the TPP enzyme family
Asera_40490	COG3718	enzyme involved in inositol metabolism
Asera_40530	COG0673	inositol 2-dehydrogenase activity
Asera_40540	COG2188	Transcriptional regulator
Asera_40560	COG0560	Phosphoserine phosphatase
Asera_40620	COG1643	Atp-dependent helicase
Asera_40660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Asera_40670	COG0412	Dienelactone hydrolase
Asera_40730	COG0006	proline dipeptidase activity
Asera_40770	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_40790	COG1960	acyl-CoA dehydrogenase activity
Asera_40830	COG0747	negative chemotaxis
Asera_40840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_40850	COG0601	transmembrane transport
Asera_40880	COG0596	Alpha beta hydrolase
Asera_40940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asera_40970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_40990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Asera_41020	COG0006	proline dipeptidase activity
Asera_41040	COG1511	domain protein
Asera_41050	COG1136	(ABC) transporter
Asera_41070	COG1309	transcriptional regulator
Asera_41090	COG1119	ATPase activity
Asera_41100	COG3629	intracellular signal transduction
Asera_41100	COG3903	Transcriptional regulator
Asera_41120	COG0583	DNA-binding transcription factor activity
Asera_41130	COG0667	Aldo Keto reductase
Asera_41140	COG0823	Involved in the tonB-independent uptake of proteins
Asera_41170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asera_41180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_41200	COG1595	DNA-templated transcription, initiation
Asera_41240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asera_41310	COG0697	spore germination
Asera_41370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Asera_41420	COG0714	Associated with various cellular activities
Asera_41450	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_41460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Asera_41470	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Asera_41500	COG0791	NLP P60 protein
Asera_41500	COG3883	PFAM NLP P60 protein
Asera_41560	COG1653	transport
Asera_41570	COG1175	transmembrane transport
Asera_41580	COG0395	ABC-type sugar transport system, permease component
Asera_41610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Asera_41620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Asera_41630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_41660	COG4221	oxidoreductase activity
Asera_41700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asera_41710	COG1733	regulation of RNA biosynthetic process
Asera_41720	COG0702	epimerase
Asera_41730	COG0402	S-adenosylhomocysteine deaminase activity
Asera_41780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asera_41830	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Asera_41870	COG2249	NAD(P)H dehydrogenase (quinone) activity
Asera_41890	COG1609	Transcriptional regulator
Asera_41920	COG2182	Extracellular solute-binding protein
Asera_41930	COG1175	transmembrane transport
Asera_41940	COG0395	ABC-type sugar transport system, permease component
Asera_41960	COG0443	Heat shock 70 kDa protein
Asera_42030	COG1175	transmembrane transport
Asera_42100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_42110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_42160	COG0640	Transcriptional regulator
Asera_42210	COG3328	transposase activity
Asera_42270	COG3469	chitinase activity
Asera_42290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Asera_42340	COG1595	DNA-templated transcription, initiation
Asera_42360	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Asera_42420	COG2271	Major facilitator Superfamily
Asera_42430	COG1234	tRNA 3'-trailer cleavage
Asera_42450	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_42520	COG2197	response regulator
Asera_42570	COG1716	ATPase activity
Asera_42580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Asera_42610	COG1070	Carbohydrate kinase
Asera_42650	COG2208	phosphoserine phosphatase activity
Asera_42700	COG0702	epimerase
Asera_42720	COG3795	YCII-related domain
Asera_42730	COG4941	Belongs to the sigma-70 factor family
Asera_42780	COG3903	Transcriptional regulator
Asera_42780	COG3629	intracellular signal transduction
Asera_42860	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Asera_42870	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Asera_42950	COG2815	serine threonine protein kinase
Asera_42950	COG0515	serine threonine protein kinase
Asera_43110	COG0667	Aldo Keto reductase
Asera_43120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_43130	COG0588	phosphoglycerate mutase activity
Asera_43170	COG0215	cysteine-tRNA ligase activity
Asera_43220	COG1410	methionine synthase
Asera_43220	COG0646	methionine synthase
Asera_43290	COG1476	TRANSCRIPTIONal
Asera_43300	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
Asera_43320	COG1136	(ABC) transporter
Asera_43320	COG0577	efflux transmembrane transporter activity
Asera_43330	COG1136	(ABC) transporter
Asera_43340	COG2197	response regulator
Asera_43350	COG4585	Histidine kinase
Asera_43370	COG1994	Peptidase M50
Asera_43370	COG0517	IMP dehydrogenase activity
Asera_43390	COG1222	aaa ATPase
Asera_43420	COG4122	O-methyltransferase activity
Asera_43450	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asera_43460	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asera_43470	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asera_43510	COG2378	regulation of single-species biofilm formation
Asera_43520	COG2378	regulation of single-species biofilm formation
Asera_43540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asera_43550	COG0805	protein transport
Asera_43590	COG2318	DinB family
Asera_43630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asera_43630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asera_43640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Asera_43660	COG0140	phosphoribosyl-ATP diphosphatase activity
Asera_43670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Asera_43700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Asera_43710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Asera_43720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Asera_43730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Asera_43740	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Asera_43750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asera_43750	COG0072	phenylalanine-tRNA ligase activity
Asera_43790	COG1215	transferase activity, transferring glycosyl groups
Asera_43800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Asera_43810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Asera_43820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Asera_43830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Asera_43840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Asera_43860	COG0165	Argininosuccinate lyase
Asera_43870	COG2094	Belongs to the DNA glycosylase MPG family
Asera_43880	COG0789	Transcriptional regulator
Asera_43900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Asera_43930	COG0647	UMP catabolic process
Asera_43980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Asera_43990	COG0497	DNA recombination
Asera_44030	COG0297	glycogen (starch) synthase activity
Asera_44050	COG0504	CTP synthase activity
Asera_44060	COG0494	nUDIX hydrolase
Asera_44100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Asera_44110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Asera_44140	COG4608	Belongs to the ABC transporter superfamily
Asera_44150	COG0444	Belongs to the ABC transporter superfamily
Asera_44160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_44180	COG4166	transmembrane transport
Asera_44190	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Asera_44200	COG1160	GTP binding
Asera_44230	COG0583	DNA-binding transcription factor activity
Asera_44250	COG1053	succinate dehydrogenase
Asera_44260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Asera_44270	COG1846	Transcriptional regulator
Asera_44290	COG3201	nicotinamide mononucleotide transporter
Asera_44320	COG1191	sigma factor activity
Asera_44340	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_44350	COG1063	alcohol dehydrogenase
Asera_44360	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_44380	COG1414	Transcriptional regulator
Asera_44400	COG2814	Major facilitator Superfamily
Asera_44410	COG3408	Glycogen debranching enzyme
Asera_44440	COG3250	beta-galactosidase activity
Asera_44470	COG0254	rRNA binding
Asera_44490	COG1739	Uncharacterized protein family UPF0029
Asera_44500	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Asera_44530	COG0442	prolyl-tRNA aminoacylation
Asera_44550	COG2197	response regulator
Asera_44670	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_44700	COG0583	DNA-binding transcription factor activity
Asera_44740	COG0667	Aldo Keto reductase
Asera_44780	COG0702	epimerase
Asera_44900	COG2182	Extracellular solute-binding protein
Asera_44920	COG0395	ABC-type sugar transport system, permease component
Asera_44930	COG3842	ATPase activity
Asera_44940	COG1733	regulation of RNA biosynthetic process
Asera_44950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Asera_44970	COG0456	acetyltransferase
Asera_44980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asera_45000	COG0725	ABC transporter, periplasmic molybdate-binding protein
Asera_45060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_45100	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Asera_45150	COG1191	sigma factor activity
Asera_45200	COG1554	hydrolase, family 65, central catalytic
Asera_45230	COG1960	acyl-CoA dehydrogenase activity
Asera_45250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asera_45280	COG1960	acyl-CoA dehydrogenase activity
Asera_45320	COG0406	alpha-ribazole phosphatase activity
Asera_45340	COG0604	alcohol dehydrogenase
Asera_45360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Asera_45370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_45430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Asera_45460	COG1752	Esterase of the alpha-beta hydrolase superfamily
Asera_45480	COG1435	thymidine kinase activity
Asera_45490	COG2270	Major facilitator Superfamily
Asera_45510	COG0443	Heat shock 70 kDa protein
Asera_45570	COG2197	response regulator
Asera_45590	COG1271	oxidase subunit
Asera_45600	COG1294	oxidase, subunit
Asera_45610	COG4988	ABC transporter
Asera_45620	COG1132	(ABC) transporter
Asera_45700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Asera_45750	COG4974	Belongs to the 'phage' integrase family
Asera_45770	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Asera_45780	COG1132	(ABC) transporter
Asera_45810	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_45820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_45850	COG2197	response regulator
Asera_45870	COG4941	Belongs to the sigma-70 factor family
Asera_45880	COG3795	YCII-related domain
Asera_45900	COG2814	Major facilitator Superfamily
Asera_45940	COG0477	Major facilitator Superfamily
Asera_45970	COG2318	DinB family
Asera_46020	COG2249	NAD(P)H dehydrogenase (quinone) activity
Asera_46090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_46200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Asera_46200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Asera_46240	COG1716	ATPase activity
Asera_46400	COG1051	belongs to the nudix hydrolase family
Asera_46420	COG0105	UTP biosynthetic process
Asera_46520	COG2188	Transcriptional regulator
Asera_46530	COG4821	SIS domain
Asera_46570	COG1073	alpha beta
Asera_46590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_46620	COG2814	Major facilitator Superfamily
Asera_46650	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asera_46660	COG0242	peptide deformylase activity
Asera_46680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Asera_46700	COG1758	RNA polymerase activity
Asera_46710	COG0194	GDP metabolic process
Asera_46720	COG0194	GDP metabolic process
Asera_46730	COG0284	orotidine-5'-phosphate decarboxylase activity
Asera_46740	COG0167	dihydroorotate dehydrogenase activity
Asera_46760	COG0505	Belongs to the CarA family
Asera_46770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asera_46780	COG0540	Belongs to the ATCase OTCase family
Asera_46790	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Asera_46810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Asera_46820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Asera_46840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Asera_46850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Asera_46860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Asera_46870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Asera_46920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Asera_46970	COG1461	Dihydroxyacetone kinase
Asera_46980	COG2376	Dihydroxyacetone kinase
Asera_47040	COG2197	response regulator
Asera_47050	COG4585	Histidine kinase
Asera_47070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Asera_47080	COG0124	histidyl-tRNA synthetase
Asera_47120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asera_47140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Asera_47150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Asera_47170	COG1862	Preprotein translocase
Asera_47180	COG2255	four-way junction helicase activity
Asera_47190	COG0632	four-way junction helicase activity
Asera_47200	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Asera_47220	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Asera_47230	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Asera_47250	COG0438	transferase activity, transferring glycosyl groups
Asera_47260	COG1560	Kdo2-lipid A biosynthetic process
Asera_47270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Asera_47310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asera_47330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_47340	COG2188	Transcriptional regulator
Asera_47360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Asera_47390	COG1695	Transcriptional regulator
Asera_47440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Asera_47460	COG2223	nitrite transmembrane transporter activity
Asera_47500	COG1940	carbohydrate kinase activity
Asera_47530	COG0446	pyridine nucleotide-disulphide oxidoreductase
Asera_47530	COG1902	pentaerythritol trinitrate reductase activity
Asera_47560	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_47610	COG3511	phospholipase C
Asera_47660	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_47670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asera_47680	COG0642	Histidine kinase
Asera_47700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_47740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_47750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asera_47760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Asera_47830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_47840	COG1649	PFAM Uncharacterised BCR, COG1649
Asera_47850	COG1595	DNA-templated transcription, initiation
Asera_47880	COG1316	TRANSCRIPTIONal
Asera_47900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asera_47920	COG3290	protein histidine kinase activity
Asera_47930	COG4565	transcriptional regulatory protein
Asera_47980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Asera_48030	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_48050	COG1653	transport
Asera_48060	COG1175	transmembrane transport
Asera_48090	COG4585	Histidine kinase
Asera_48100	COG2197	response regulator
Asera_48150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Asera_48160	COG3842	ATPase activity
Asera_48170	COG3022	response to hydroperoxide
Asera_48180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asera_48190	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Asera_48250	COG1802	Transcriptional regulator
Asera_48270	COG3473	Maleate cis-trans isomerase
Asera_48280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_48290	COG0154	amidase activity
Asera_48310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Asera_48340	COG0420	3'-5' exonuclease activity
Asera_48350	COG0419	ATPase involved in DNA repair
Asera_48400	COG1793	dna ligase
Asera_48420	COG0039	L-malate dehydrogenase activity
Asera_48430	COG1609	Transcriptional regulator
Asera_48460	COG1070	Carbohydrate kinase
Asera_48480	COG1175	transmembrane transport
Asera_48490	COG0395	ABC-type sugar transport system, permease component
Asera_48510	COG1765	OsmC-like protein
Asera_48530	COG4941	Belongs to the sigma-70 factor family
Asera_48560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_48600	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_48620	COG1024	Enoyl-CoA hydratase
Asera_48680	COG0488	(ABC) transporter
Asera_48710	COG2151	metal-sulfur cluster biosynthetic enzyme
Asera_48720	COG0822	iron-sulfur transferase activity
Asera_48730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asera_48740	COG0396	ATPase activity
Asera_48790	COG1612	heme a metabolic process
Asera_48810	COG1063	alcohol dehydrogenase
Asera_48820	COG3875	lactate racemase activity
Asera_48850	COG0109	protoheme IX farnesyltransferase activity
Asera_48880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Asera_48910	COG0363	glucosamine-6-phosphate deaminase activity
Asera_48930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Asera_48960	COG0149	triose-phosphate isomerase activity
Asera_48970	COG0126	phosphoglycerate kinase activity
Asera_48980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Asera_48990	COG1481	regulation of sporulation
Asera_49010	COG1660	Displays ATPase and GTPase activities
Asera_49020	COG0322	excinuclease ABC activity
Asera_49050	COG1162	GTPase activity
Asera_49060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_49090	COG1217	gtp-binding protein TYPA
Asera_49130	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_49140	COG0791	NLP P60 protein
Asera_49160	COG2329	Antibiotic biosynthesis monooxygenase
Asera_49210	COG2197	response regulator
Asera_49220	COG4585	Histidine kinase
Asera_49240	COG1131	(ABC) transporter
Asera_49250	COG0237	dephospho-CoA kinase activity
Asera_49250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Asera_49280	COG2226	methyltransferase
Asera_49300	COG2362	D-Aminopeptidase
Asera_49310	COG0531	amino acid
Asera_49350	COG0765	amino acid transport
Asera_49360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_49490	COG3345	alpha-galactosidase
Asera_49500	COG1946	Acyl-CoA thioesterase
Asera_49660	COG1802	Transcriptional regulator
Asera_49680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Asera_49690	COG3716	PTS system mannose fructose sorbose family IID component
Asera_49700	COG3715	PTS system
Asera_49720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asera_49730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asera_49750	COG1522	sequence-specific DNA binding
Asera_49770	COG0067	glutamate synthase
Asera_49770	COG0070	glutamate synthase
Asera_49770	COG0069	glutamate synthase activity
Asera_49820	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Asera_49850	COG0133	tryptophan synthase activity
Asera_49890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Asera_49920	COG1132	(ABC) transporter
Asera_49930	COG1132	(ABC) transporter
Asera_49950	COG2364	Membrane
Asera_49960	COG0107	imidazoleglycerol-phosphate synthase activity
Asera_49970	COG0251	oxidation-reduction process
Asera_49980	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Asera_50010	COG0131	Imidazoleglycerol-phosphate dehydratase
Asera_50020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asera_50030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Asera_50040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Asera_50060	COG0587	DNA-directed DNA polymerase activity
Asera_50090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Asera_50100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Asera_50120	COG3599	regulation of cell shape
Asera_50140	COG1799	cell septum assembly
Asera_50150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Asera_50170	COG2318	DinB family
Asera_50180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Asera_50190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Asera_50200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asera_50220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Asera_50230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Asera_50250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Asera_50260	COG0768	penicillin binding
Asera_50280	COG0275	rRNA processing
Asera_50290	COG2001	Belongs to the MraZ family
Asera_50310	COG3442	glutamine amidotransferase
Asera_50330	COG0495	leucyl-tRNA aminoacylation
Asera_50350	COG0714	Associated with various cellular activities
Asera_50390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Asera_50440	COG2124	cytochrome p450
Asera_50470	COG0587	DNA-directed DNA polymerase activity
Asera_50520	COG0339	signal peptide processing
Asera_50560	COG1309	transcriptional regulator
Asera_50600	COG0142	geranyltranstransferase activity
Asera_50640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asera_50650	COG1126	abc transporter atp-binding protein
Asera_50660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_50670	COG0765	amino acid transport
Asera_50680	COG0765	amino acid transport
Asera_50690	COG0438	transferase activity, transferring glycosyl groups
Asera_50720	COG1418	mRNA catabolic process
Asera_50730	COG2137	regulation of response to DNA damage stimulus
Asera_50740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Asera_50780	COG1201	RNA secondary structure unwinding
Asera_50840	COG1842	Phage shock protein A
Asera_50850	COG1396	sequence-specific DNA binding
Asera_50860	COG1546	Belongs to the CinA family
Asera_50860	COG1058	Belongs to the CinA family
Asera_50870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Asera_50880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asera_50910	COG0443	Heat shock 70 kDa protein
Asera_50920	COG1674	ftsk spoiiie
Asera_50970	COG3619	membrane
Asera_50980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Asera_50990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asera_51000	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Asera_51050	COG3214	Protein conserved in bacteria
Asera_51080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Asera_51090	COG0612	Peptidase, M16
Asera_51100	COG1185	polyribonucleotide nucleotidyltransferase activity
Asera_51110	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Asera_51130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Asera_51150	COG0477	Major facilitator Superfamily
Asera_51180	COG0534	Mate efflux family protein
Asera_51190	COG1234	tRNA 3'-trailer cleavage
Asera_51230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Asera_51240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Asera_51300	COG1522	sequence-specific DNA binding
Asera_51320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Asera_51340	COG0779	Required for maturation of 30S ribosomal subunits
Asera_51450	COG0514	ATP-dependent DNA helicase (RecQ)
Asera_51510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Asera_51540	COG0456	acetyltransferase
Asera_51550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Asera_51560	COG0750	zinc metalloprotease
Asera_51590	COG2076	Multidrug Resistance protein
Asera_51610	COG0277	FAD linked oxidase domain protein
Asera_51680	COG2146	nitrite reductase [NAD(P)H] activity
Asera_51680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Asera_51710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Asera_51720	COG0575	Belongs to the CDS family
Asera_51730	COG0233	cytoplasmic translational termination
Asera_51740	COG0528	UMP kinase activity
Asera_51750	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Asera_51760	COG0052	Belongs to the universal ribosomal protein uS2 family
Asera_51830	COG4974	Belongs to the 'phage' integrase family
Asera_51870	COG0792	nuclease activity
Asera_51900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Asera_51910	COG0681	Belongs to the peptidase S26 family
Asera_51920	COG0335	large ribosomal subunit rRNA binding
Asera_51930	COG0336	Belongs to the RNA methyltransferase TrmD family
Asera_51940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Asera_51950	COG1837	Belongs to the UPF0109 family
Asera_51960	COG0228	four-way junction DNA binding
Asera_51990	COG4608	Belongs to the ABC transporter superfamily
Asera_52000	COG0444	Belongs to the ABC transporter superfamily
Asera_52020	COG4166	transmembrane transport
Asera_52030	COG0601	transmembrane transport
Asera_52040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_52060	COG0596	Alpha beta hydrolase
Asera_52080	COG0442	prolyl-tRNA aminoacylation
Asera_52180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Asera_52230	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Asera_52260	COG0653	protein targeting
Asera_52320	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_52340	COG1011	Hydrolase
Asera_52380	COG3548	integral membrane protein
Asera_52390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_52410	COG0571	ribonuclease III activity
Asera_52420	COG0416	fatty acid biosynthetic process
Asera_52430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Asera_52460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Asera_52470	COG0742	ribosomal rna small subunit methyltransferase
Asera_52500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Asera_52570	COG0589	response to stress
Asera_52600	COG0626	cystathionine gamma-synthase activity
Asera_52610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Asera_52640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Asera_52650	COG0406	alpha-ribazole phosphatase activity
Asera_52650	COG0494	nUDIX hydrolase
Asera_52670	COG0066	3-isopropylmalate dehydratase activity
Asera_52680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Asera_52710	COG2226	methyltransferase
Asera_52720	COG0546	phosphoglycolate phosphatase activity
Asera_52730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Asera_52740	COG0179	Fumarylacetoacetate (FAA) hydrolase
Asera_52760	COG2197	response regulator
Asera_52770	COG4585	Histidine kinase
Asera_52800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asera_52810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Asera_52830	COG0473	3-isopropylmalate dehydrogenase activity
Asera_52850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Asera_52860	COG0440	acetolactate synthase activity
Asera_52870	COG0028	Belongs to the TPP enzyme family
Asera_52890	COG0129	dihydroxy-acid dehydratase activity
Asera_52950	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_52960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asera_53010	COG2133	pyrroloquinoline quinone binding
Asera_53040	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Asera_53050	COG0154	amidase activity
Asera_53060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Asera_53080	COG0596	Alpha beta hydrolase
Asera_53100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Asera_53160	COG0667	Aldo Keto reductase
Asera_53180	COG0583	DNA-binding transcription factor activity
Asera_53190	COG0482	sulfurtransferase activity
Asera_53250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Asera_53310	COG3979	chitinase
Asera_53330	COG0110	maltose O-acetyltransferase activity
Asera_53370	COG1119	ATPase activity
Asera_53400	COG1609	Transcriptional regulator
Asera_53410	COG1725	Transcriptional regulator
Asera_53430	COG1940	carbohydrate kinase activity
Asera_53430	COG1846	Transcriptional regulator
Asera_53440	COG2182	Extracellular solute-binding protein
Asera_53450	COG1175	transmembrane transport
Asera_53460	COG0395	ABC-type sugar transport system, permease component
Asera_53490	COG0366	Alpha amylase catalytic
Asera_53500	COG0366	Alpha amylase catalytic
Asera_53540	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Asera_53560	COG0515	serine threonine protein kinase
Asera_53570	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Asera_53600	COG1309	transcriptional regulator
Asera_53620	COG0789	Transcriptional regulator
Asera_53630	COG0431	NADPH-dependent FMN reductase
Asera_53670	COG4988	ABC transporter
Asera_53690	COG1271	oxidase subunit
Asera_53720	COG2902	Dehydrogenase
Asera_53730	COG0010	Belongs to the arginase family
Asera_53750	COG2188	Transcriptional regulator
Asera_53780	COG4260	virion core protein, lumpy skin disease virus
Asera_53820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_53830	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_53830	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_53840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Asera_53890	COG1136	(ABC) transporter
Asera_53900	COG1136	(ABC) transporter
Asera_53940	COG0183	Belongs to the thiolase family
Asera_53950	COG0346	lactoylglutathione lyase activity
Asera_53980	COG2860	membrane
Asera_54030	COG0667	Aldo Keto reductase
Asera_54050	COG0789	Transcriptional regulator
Asera_54060	COG3118	belongs to the thioredoxin family
Asera_54090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asera_54100	COG2183	response to ionizing radiation
Asera_54140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Asera_54170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Asera_54190	COG2226	methyltransferase
Asera_54200	COG1515	deoxyribonuclease V activity
Asera_54210	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_54220	COG1129	ABC transporter
Asera_54240	COG1609	Transcriptional regulator
Asera_54250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Asera_54270	COG0277	FAD linked oxidase domain protein
Asera_54320	COG3386	PFAM SMP-30 Gluconolaconase
Asera_54420	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Asera_54430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asera_54440	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_54460	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_54470	COG0179	Fumarylacetoacetate (FAA) hydrolase
Asera_54480	COG3618	amidohydrolase
Asera_54510	COG0247	lactate metabolic process
Asera_54520	COG0247	lactate metabolic process
Asera_54530	COG1139	Iron-sulfur cluster binding protein
Asera_54540	COG1556	Lactate utilization protein
Asera_54560	COG1131	(ABC) transporter
Asera_54590	COG1595	DNA-templated transcription, initiation
Asera_54640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asera_54650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Asera_54670	COG2226	methyltransferase
Asera_54690	COG1414	Transcriptional regulator
Asera_54720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_54730	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_54780	COG2197	response regulator
Asera_54790	COG4585	Histidine kinase
Asera_54820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Asera_54820	COG1213	nucleotidyl transferase
Asera_54850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_54860	COG1278	Cold shock
Asera_54940	COG0515	serine threonine protein kinase
Asera_54990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asera_55050	COG3360	Dodecin
Asera_55060	COG0583	DNA-binding transcription factor activity
Asera_55100	COG4257	antibiotic catabolic process
Asera_55190	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Asera_55200	COG3387	PFAM Glycoside hydrolase 15-related
Asera_55210	COG5285	phytanoyl-CoA dioxygenase
Asera_55230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Asera_55240	COG0456	acetyltransferase
Asera_55250	COG1648	precorrin-2 dehydrogenase activity
Asera_55250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Asera_55290	COG1797	cobyrinic acid a,c-diamide synthase activity
Asera_55310	COG1793	dna ligase
Asera_55330	COG1994	Peptidase M50
Asera_55340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asera_55350	COG0501	Belongs to the peptidase M48B family
Asera_55360	COG1492	cobalamin metabolic process
Asera_55370	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Asera_55380	COG0629	single-stranded DNA binding
Asera_55390	COG1609	Transcriptional regulator
Asera_55490	COG2226	methyltransferase
Asera_55500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Asera_55520	COG0121	glutamine amidotransferase
Asera_55530	COG0387	Pfam Sodium calcium exchanger
Asera_55560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Asera_55570	COG1595	DNA-templated transcription, initiation
Asera_55650	COG1595	DNA-templated transcription, initiation
Asera_55720	COG0789	Transcriptional regulator
Asera_55740	COG1175	transmembrane transport
Asera_55750	COG0395	ABC-type sugar transport system, permease component
Asera_55790	COG2409	Drug exporters of the RND superfamily
Asera_55810	COG0156	8-amino-7-oxononanoate synthase activity
Asera_55850	COG1063	alcohol dehydrogenase
Asera_55910	COG0477	Major facilitator Superfamily
Asera_55930	COG1175	transmembrane transport
Asera_55940	COG1653	transport
Asera_55950	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_55960	COG1609	Transcriptional regulator
Asera_56030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Asera_56070	COG0714	Associated with various cellular activities
Asera_56110	COG1609	Transcriptional regulator
Asera_56120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asera_56150	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Asera_56170	COG4266	Belongs to the allantoicase family
Asera_56180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asera_56290	COG0701	Predicted permease
Asera_56350	COG0667	Aldo Keto reductase
Asera_56380	COG3340	Belongs to the peptidase S51 family
Asera_56470	COG0577	efflux transmembrane transporter activity
Asera_56470	COG1136	(ABC) transporter
Asera_56520	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_56550	COG3903	Transcriptional regulator
Asera_56550	COG3629	intracellular signal transduction
Asera_56570	COG2814	Major facilitator Superfamily
Asera_56590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_56620	COG4566	intracellular signal transduction
Asera_56630	COG0438	transferase activity, transferring glycosyl groups
Asera_56670	COG1215	transferase activity, transferring glycosyl groups
Asera_56680	COG3858	chitin binding
Asera_56680	COG1388	LysM domain
Asera_56700	COG0438	transferase activity, transferring glycosyl groups
Asera_56720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asera_56780	COG2409	Drug exporters of the RND superfamily
Asera_56800	COG1309	transcriptional regulator
Asera_56870	COG3795	YCII-related domain
Asera_56880	COG4941	Belongs to the sigma-70 factor family
Asera_56950	COG2986	histidine ammonia-lyase
Asera_56990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Asera_57030	COG2197	response regulator
Asera_57100	COG0215	cysteine-tRNA ligase activity
Asera_57210	COG2197	response regulator
Asera_57250	COG1309	transcriptional regulator
Asera_57270	COG1134	teichoic acid transport
Asera_57310	COG3119	arylsulfatase activity
Asera_57360	COG3119	arylsulfatase activity
Asera_57370	COG3119	arylsulfatase activity
Asera_57380	COG0395	ABC-type sugar transport system, permease component
Asera_57390	COG1175	transmembrane transport
Asera_57400	COG2182	Extracellular solute-binding protein
Asera_57420	COG1869	D-ribose catabolic process
Asera_57430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_57440	COG1609	Transcriptional regulator
Asera_57460	COG0778	Nitroreductase
Asera_57480	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_57540	COG0640	Transcriptional regulator
Asera_57550	COG2226	methyltransferase
Asera_57620	COG4552	Acetyltransferase involved in intracellular survival and related
Asera_57650	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_57660	COG1129	ABC transporter
Asera_57670	COG1414	Transcriptional regulator
Asera_57690	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_57780	COG2132	Multicopper oxidase
Asera_57830	COG2151	metal-sulfur cluster biosynthetic enzyme
Asera_57850	COG0702	epimerase
Asera_57880	COG3321	synthase
Asera_57880	COG0604	alcohol dehydrogenase
Asera_57890	COG1234	tRNA 3'-trailer cleavage
Asera_57940	COG1921	L-seryl-tRNASec selenium transferase activity
Asera_57950	COG0709	Synthesizes selenophosphate from selenide and ATP
Asera_58100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asera_58110	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_58150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_58300	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_58340	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_58350	COG0247	lactate metabolic process
Asera_58350	COG0277	FAD linked oxidase domain protein
Asera_58390	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_58400	COG0028	Belongs to the TPP enzyme family
Asera_58430	COG0437	4 iron, 4 sulfur cluster binding
Asera_58520	COG0651	ATP synthesis coupled electron transport
Asera_58530	COG1006	Multisubunit Na H antiporter MnhC subunit
Asera_58660	COG1131	(ABC) transporter
Asera_58670	COG1309	transcriptional regulator
Asera_58690	COG1131	(ABC) transporter
Asera_58720	COG0656	L-ascorbic acid biosynthetic process
Asera_58740	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asera_58750	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Asera_58760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asera_58780	COG2205	protein histidine kinase activity
Asera_58790	COG0745	RESPONSE REGULATOR receiver
Asera_58810	COG2094	Belongs to the DNA glycosylase MPG family
Asera_58890	COG4941	Belongs to the sigma-70 factor family
Asera_58940	COG0513	Belongs to the DEAD box helicase family
Asera_58970	COG1131	(ABC) transporter
Asera_58980	COG0745	RESPONSE REGULATOR receiver
Asera_58990	COG2205	protein histidine kinase activity
Asera_59000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_59010	COG0747	negative chemotaxis
Asera_59020	COG0601	transmembrane transport
Asera_59030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_59050	COG4608	Belongs to the ABC transporter superfamily
Asera_59100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Asera_59130	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_59190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Asera_59230	COG2326	polyphosphate kinase activity
Asera_59280	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asera_59280	COG1672	PFAM Archaeal ATPase
Asera_59300	COG3848	Pyruvate phosphate dikinase
Asera_59300	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_59300	COG3848	Pyruvate phosphate dikinase
Asera_59300	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_59360	COG2207	Transcriptional regulator
Asera_59420	COG2226	methyltransferase
Asera_59450	COG1733	regulation of RNA biosynthetic process
Asera_59470	COG2816	NAD+ diphosphatase activity
Asera_59480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_59500	COG1280	lysine exporter protein (LysE YggA)
Asera_59520	COG2353	YceI-like domain
Asera_59580	COG2068	MobA-Related Protein
Asera_59690	COG4989	oxidoreductase activity
Asera_59740	COG2070	2-Nitropropane dioxygenase
Asera_59780	COG0702	epimerase
Asera_59790	COG4221	oxidoreductase activity
Asera_59810	COG2801	Transposase and inactivated derivatives
Asera_59890	COG0038	chloride channel
Asera_59920	COG3328	transposase activity
Asera_59940	COG3328	transposase activity
Asera_59960	COG2801	Transposase and inactivated derivatives
Asera_60140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_60210	COG2197	response regulator
Asera_60470	COG2801	Transposase and inactivated derivatives
Asera_60570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Asera_60580	COG1381	Involved in DNA repair and RecF pathway recombination
Asera_60600	COG0667	Aldo Keto reductase
Asera_60650	COG0714	Associated with various cellular activities
Asera_60670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Asera_60700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Asera_60730	COG0537	adenosine 5'-monophosphoramidase activity
Asera_60750	COG0484	heat shock protein binding
Asera_60760	COG1420	regulation of RNA biosynthetic process
Asera_60790	COG1024	Enoyl-CoA hydratase
Asera_60820	COG1309	transcriptional regulator
Asera_60860	COG0481	GTPase activity
Asera_60870	COG0268	Binds directly to 16S ribosomal RNA
Asera_60910	COG1555	photosystem II stabilization
Asera_60930	COG0406	alpha-ribazole phosphatase activity
Asera_60940	COG0799	negative regulation of ribosome biogenesis
Asera_60950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Asera_60970	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Asera_61020	COG0180	Tryptophanyl-tRNA synthetase
Asera_61050	COG0745	RESPONSE REGULATOR receiver
Asera_61060	COG2205	protein histidine kinase activity
Asera_61100	COG3345	alpha-galactosidase
Asera_61140	COG0698	ribose 5-phosphate isomerase
Asera_61160	COG0640	Transcriptional regulator
Asera_61200	COG0673	inositol 2-dehydrogenase activity
Asera_61280	COG0667	Aldo Keto reductase
Asera_61290	COG1309	transcriptional regulator
Asera_61310	COG0285	dihydrofolate synthase activity
Asera_61320	COG0525	valine-tRNA ligase activity
Asera_61360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Asera_61370	COG0740	serine-type endopeptidase activity
Asera_61380	COG0740	serine-type endopeptidase activity
Asera_61390	COG0544	peptidyl-prolyl cis-trans isomerase activity
Asera_61500	COG0514	ATP-dependent DNA helicase (RecQ)
Asera_61580	COG2135	peptidase activity
Asera_61610	COG2119	membrane
Asera_61640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Asera_61650	COG0515	serine threonine protein kinase
Asera_61660	COG4552	Acetyltransferase involved in intracellular survival and related
Asera_61690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asera_61750	COG1280	lysine exporter protein (LysE YggA)
Asera_61780	COG0702	epimerase
Asera_61790	COG1309	transcriptional regulator
Asera_61810	COG0105	UTP biosynthetic process
Asera_61840	COG2186	Transcriptional regulator
Asera_61890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Asera_61920	COG2318	DinB family
Asera_61930	COG3336	cytochrome c oxidase
Asera_61990	COG2197	response regulator
Asera_62080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Asera_62120	COG1674	ftsk spoiiie
Asera_62190	COG1404	Belongs to the peptidase S8 family
Asera_62200	COG4585	Histidine kinase
Asera_62230	COG0860	N-Acetylmuramoyl-L-alanine amidase
Asera_62260	COG1584	GPR1 FUN34 yaaH family protein
Asera_62270	COG1376	ErfK ybiS ycfS ynhG family protein
Asera_62300	COG3458	cephalosporin-C deacetylase activity
Asera_62430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_62460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_62540	COG5001	Diguanylate cyclase
Asera_62540	COG3300	MHYT domain
Asera_62580	COG0477	Major facilitator Superfamily
Asera_62600	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asera_62600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asera_62610	COG1309	transcriptional regulator
Asera_62660	COG1140	nitrate reductase beta subunit
Asera_62700	COG1309	transcriptional regulator
Asera_62710	COG2409	Drug exporters of the RND superfamily
Asera_62730	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Asera_62760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Asera_62860	COG0640	Transcriptional regulator
Asera_62870	COG1191	sigma factor activity
Asera_62880	COG2814	Major facilitator Superfamily
Asera_62900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_62910	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_62920	COG0022	dehydrogenase e1 component
Asera_62930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Asera_63130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_63190	COG0667	Aldo Keto reductase
Asera_63240	COG1307	EDD domain protein, DegV family
Asera_63250	COG1486	melibiose metabolic process
Asera_63280	COG1733	regulation of RNA biosynthetic process
Asera_63290	COG0183	Belongs to the thiolase family
Asera_63350	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_63360	COG1309	transcriptional regulator
Asera_63370	COG0477	Major facilitator Superfamily
Asera_63450	COG0596	Alpha beta hydrolase
Asera_63480	COG0596	Alpha beta hydrolase
Asera_63490	COG2197	response regulator
Asera_63550	COG0765	amino acid transport
Asera_63690	COG0110	maltose O-acetyltransferase activity
Asera_63760	COG0667	Aldo Keto reductase
Asera_63820	COG1309	transcriptional regulator
Asera_63930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_63950	COG2826	transposase and inactivated derivatives, IS30 family
Asera_63960	COG3328	transposase activity
Asera_63970	COG1309	transcriptional regulator
Asera_64170	COG3328	transposase activity
Asera_64240	COG0640	Transcriptional regulator
Asera_64360	COG1678	Uncharacterized ACR, COG1678
Asera_64370	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Asera_64390	COG5002	protein histidine kinase activity
Asera_64400	COG0745	RESPONSE REGULATOR receiver
Asera_64510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Asera_64520	COG2177	Part of the ABC transporter FtsEX involved in
Asera_64530	COG2884	Cell division ATP-binding protein ftsE
Asera_64540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Asera_64560	COG0515	serine threonine protein kinase
Asera_64570	COG3483	tryptophan 2,3-dioxygenase activity
Asera_64600	COG1012	belongs to the aldehyde dehydrogenase family
Asera_64680	COG1799	cell septum assembly
Asera_64700	COG0653	protein targeting
Asera_64730	COG0435	Glutathione S-transferase
Asera_64750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Asera_64790	COG5401	PFAM Sporulation and spore germination
Asera_64800	COG5000	phosphorelay sensor kinase activity
Asera_64800	COG5002	protein histidine kinase activity
Asera_64810	COG0745	RESPONSE REGULATOR receiver
Asera_64820	COG2807	transmembrane transport
Asera_64830	COG2186	Transcriptional regulator
Asera_64870	COG0714	Associated with various cellular activities
Asera_65020	COG1376	ErfK ybiS ycfS ynhG family protein
Asera_65030	COG0604	alcohol dehydrogenase
Asera_65060	COG1136	(ABC) transporter
Asera_65110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Asera_65120	COG1408	metallophosphoesterase
Asera_65250	COG0464	growth
Asera_65350	COG1674	ftsk spoiiie
Asera_65400	COG1404	Belongs to the peptidase S8 family
Asera_65430	COG0659	secondary active sulfate transmembrane transporter activity
Asera_65560	COG4585	Histidine kinase
Asera_65570	COG2197	response regulator
Asera_65610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Asera_65620	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Asera_65640	COG0402	S-adenosylhomocysteine deaminase activity
Asera_65660	COG1228	amidohydrolase
Asera_65680	COG2197	response regulator
Asera_65730	COG1017	nitric oxide dioxygenase activity
Asera_65730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asera_65750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asera_65770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Asera_65790	COG1522	sequence-specific DNA binding
Asera_65800	COG1285	pathogenesis
Asera_65820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_65830	COG0673	inositol 2-dehydrogenase activity
Asera_65850	COG2205	protein histidine kinase activity
Asera_65860	COG0745	RESPONSE REGULATOR receiver
Asera_65930	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
Asera_65950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Asera_65970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Asera_66010	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_66010	COG0567	Dehydrogenase, E1 component
Asera_66040	COG0673	inositol 2-dehydrogenase activity
Asera_66050	COG0583	DNA-binding transcription factor activity