locus-tag	class	description
Athai_00020	COG0494	nUDIX hydrolase
Athai_00030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Athai_00040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Athai_00060	COG1175	transmembrane transport
Athai_00080	COG1653	transport
Athai_00090	COG0584	glycerophosphoryl diester phosphodiesterase
Athai_00150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Athai_00190	COG0667	Aldo Keto reductase
Athai_00220	COG1136	(ABC) transporter
Athai_00240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Athai_00250	COG0604	alcohol dehydrogenase
Athai_00250	COG4221	oxidoreductase activity
Athai_00250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Athai_00250	COG3321	synthase
Athai_00290	COG0515	serine threonine protein kinase
Athai_00300	COG0842	Transport permease protein
Athai_00300	COG1131	(ABC) transporter
Athai_00300	COG1716	ATPase activity
Athai_00320	COG2801	Transposase and inactivated derivatives
Athai_00320	COG3415	Transposase
Athai_00390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Athai_00400	COG2197	response regulator
Athai_00410	COG4585	Histidine kinase
Athai_00430	COG1131	(ABC) transporter
Athai_00460	COG0456	acetyltransferase
Athai_00470	COG0745	RESPONSE REGULATOR receiver
Athai_00560	COG0025	NhaP-type Na H and K H
Athai_00580	COG4044	May play a role in the intracellular transport of hydrophobic ligands
Athai_00590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Athai_00630	COG3246	L-lysine catabolic process to acetate
Athai_00640	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_00720	COG0789	Transcriptional regulator
Athai_00750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Athai_00780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Athai_00790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Athai_00800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Athai_00820	COG0163	prenyltransferase activity
Athai_00850	COG0114	fumarate hydratase activity
Athai_00860	COG1414	Transcriptional regulator
Athai_00870	COG0215	cysteine-tRNA ligase activity
Athai_00880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Athai_00910	COG3842	ATPase activity
Athai_00980	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Athai_01030	COG1175	transmembrane transport
Athai_01040	COG0395	ABC-type sugar transport system, permease component
Athai_01050	COG1653	transport
Athai_01060	COG3104	oligopeptide transport
Athai_01090	COG1309	transcriptional regulator
Athai_01120	COG2207	Transcriptional regulator
Athai_01150	COG3263	regulation of cellular component size
Athai_01200	COG0037	tRNA processing
Athai_01220	COG2027	D-alanyl-D-alanine carboxypeptidase
Athai_01230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Athai_01250	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_01280	COG0456	acetyltransferase
Athai_01280	COG1846	Transcriptional regulator
Athai_01300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Athai_01310	COG0584	glycerophosphoryl diester phosphodiesterase
Athai_01330	COG0395	ABC-type sugar transport system, permease component
Athai_01340	COG1175	transmembrane transport
Athai_01390	COG1774	PSP1 C-terminal conserved region
Athai_01450	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Athai_01460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Athai_01470	COG0302	gtp cyclohydrolase
Athai_01630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Athai_01640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Athai_01660	COG1172	Belongs to the binding-protein-dependent transport system permease family
Athai_01690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Athai_01700	COG1174	glycine betaine transport
Athai_01730	COG0649	NAD binding
Athai_01740	COG0506	proline dehydrogenase activity
Athai_01810	COG0560	Phosphoserine phosphatase
Athai_01830	COG1595	DNA-templated transcription, initiation
Athai_01840	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_01880	COG1051	belongs to the nudix hydrolase family
Athai_01900	COG1733	regulation of RNA biosynthetic process
Athai_01950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Athai_01960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Athai_02100	COG2267	carboxylic ester hydrolase activity
Athai_02120	COG0789	Transcriptional regulator
Athai_02200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Athai_02210	COG1111	helicase
Athai_02210	COG1205	dead DEAH box helicase
Athai_02220	COG1366	Belongs to the anti-sigma-factor antagonist family
Athai_02240	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Athai_02290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Athai_02290	COG1754	DNA topoisomerase type I activity
Athai_02340	COG0456	acetyltransferase
Athai_02420	COG1309	transcriptional regulator
Athai_02450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Athai_02460	COG0470	DNA polymerase III
Athai_02550	COG1595	DNA-templated transcription, initiation
Athai_02610	COG1940	carbohydrate kinase activity
Athai_02640	COG1349	DNA-binding transcription factor activity
Athai_02660	COG1472	Belongs to the glycosyl hydrolase 3 family
Athai_02670	COG4166	transmembrane transport
Athai_02710	COG4608	Belongs to the ABC transporter superfamily
Athai_02810	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Athai_02820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Athai_02830	COG1131	(ABC) transporter
Athai_02860	COG0640	Transcriptional regulator
Athai_02890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Athai_02940	COG1278	Cold shock
Athai_02990	COG0459	protein refolding
Athai_03040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Athai_03050	COG1472	Belongs to the glycosyl hydrolase 3 family
Athai_03060	COG3876	Protein conserved in bacteria
Athai_03070	COG1737	Transcriptional regulator
Athai_03080	COG0456	acetyltransferase
Athai_03090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Athai_03160	COG1522	sequence-specific DNA binding
Athai_03170	COG1252	NADH dehydrogenase
Athai_03180	COG1595	DNA-templated transcription, initiation
Athai_03190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Athai_03250	COG4991	sh3 domain protein
Athai_03310	COG0584	glycerophosphoryl diester phosphodiesterase
Athai_03330	COG1278	Cold shock
Athai_03360	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Athai_03370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Athai_03380	COG2814	Major facilitator Superfamily
Athai_03470	COG0745	RESPONSE REGULATOR receiver
Athai_03480	COG2205	protein histidine kinase activity
Athai_03490	COG2252	PERMEase
Athai_03610	COG0259	pyridoxamine-phosphate oxidase activity
Athai_03640	COG1733	regulation of RNA biosynthetic process
Athai_03650	COG2017	converts alpha-aldose to the beta-anomer
Athai_03690	COG0596	Alpha beta hydrolase
Athai_03710	COG0477	Major facilitator Superfamily
Athai_03720	COG1760	l-serine dehydratase
Athai_03760	COG0242	peptide deformylase activity
Athai_03780	COG2271	Major facilitator Superfamily
Athai_03790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Athai_03820	COG0583	DNA-binding transcription factor activity
Athai_03830	COG2814	Major facilitator Superfamily
Athai_03860	COG0667	Aldo Keto reductase
Athai_03880	COG4152	abc transporter atp-binding protein
Athai_03950	COG2409	Drug exporters of the RND superfamily
Athai_03960	COG0483	inositol monophosphate 1-phosphatase activity
Athai_03980	COG0142	geranyltranstransferase activity
Athai_03990	COG0142	geranyltranstransferase activity
Athai_04030	COG2318	DinB family
Athai_04060	COG0791	NLP P60 protein
Athai_04070	COG1937	Protein conserved in bacteria
Athai_04150	COG3842	ATPase activity
Athai_04210	COG1970	mechanosensitive ion channel activity
Athai_04240	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Athai_04260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Athai_04350	COG0443	Heat shock 70 kDa protein
Athai_04390	COG2423	ornithine cyclodeaminase activity
Athai_04430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Athai_04440	COG1253	flavin adenine dinucleotide binding
Athai_04460	COG0084	hydrolase, TatD family'
Athai_04480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Athai_04500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Athai_04510	COG0488	(ABC) transporter
Athai_04520	COG0667	Aldo Keto reductase
Athai_04540	COG1309	transcriptional regulator
Athai_04560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Athai_04570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Athai_04580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Athai_04590	COG0193	aminoacyl-tRNA hydrolase activity
Athai_04610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Athai_04620	COG1218	3'(2'),5'-bisphosphate nucleotidase
Athai_04670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Athai_04690	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_04700	COG1309	transcriptional regulator
Athai_04710	COG2755	lipolytic protein G-D-S-L family
Athai_04790	COG0730	response to heat
Athai_04800	COG0529	Catalyzes the synthesis of activated sulfate
Athai_04810	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Athai_04830	COG0326	Molecular chaperone. Has ATPase activity
Athai_04900	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_04910	COG1309	transcriptional regulator
Athai_04960	COG2409	Drug exporters of the RND superfamily
Athai_05090	COG0148	phosphopyruvate hydratase activity
Athai_05160	COG0714	Associated with various cellular activities
Athai_05200	COG2755	lipolytic protein G-D-S-L family
Athai_05200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Athai_05220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Athai_05240	COG0328	RNA-DNA hybrid ribonuclease activity
Athai_05310	COG0076	glutamate decarboxylase activity
Athai_05350	COG0183	Belongs to the thiolase family
Athai_05370	COG2755	lipolytic protein G-D-S-L family
Athai_05380	COG3467	pyridoxamine 5'-phosphate
Athai_05400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Athai_05450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Athai_05460	COG0537	adenosine 5'-monophosphoramidase activity
Athai_05510	COG1051	belongs to the nudix hydrolase family
Athai_05570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Athai_05620	COG1331	Highly conserved protein containing a thioredoxin domain
Athai_05670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Athai_05690	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Athai_05740	COG1722	exodeoxyribonuclease VII activity
Athai_05750	COG1570	exodeoxyribonuclease VII activity
Athai_05760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Athai_05790	COG1322	Protein conserved in bacteria
Athai_05820	COG0525	valine-tRNA ligase activity
Athai_05850	COG1132	(ABC) transporter
Athai_05860	COG1132	(ABC) transporter
Athai_05880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Athai_05880	COG2169	Transcriptional regulator
Athai_05900	COG2409	Drug exporters of the RND superfamily
Athai_05910	COG2197	response regulator
Athai_05930	COG0012	GTP binding
Athai_05970	COG2076	Multidrug Resistance protein
Athai_05980	COG2076	Multidrug Resistance protein
Athai_05990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Athai_06020	COG0640	Transcriptional regulator
Athai_06040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Athai_06070	COG0494	nUDIX hydrolase
Athai_06080	COG4762	Protein conserved in bacteria
Athai_06110	COG1053	succinate dehydrogenase
Athai_06140	COG2154	pterin-4-alpha-carbinolamine dehydratase
Athai_06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_06170	COG0747	negative chemotaxis
Athai_06190	COG2018	Roadblock/LC7 domain
Athai_06240	COG1012	belongs to the aldehyde dehydrogenase family
Athai_06250	COG1012	belongs to the aldehyde dehydrogenase family
Athai_06260	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Athai_06290	COG3226	Transcriptional regulator
Athai_06310	COG2132	Multicopper oxidase
Athai_06390	COG0604	alcohol dehydrogenase
Athai_06390	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_06390	COG3321	synthase
Athai_06400	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_06400	COG0204	Acyl-transferase
Athai_06420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Athai_06430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Athai_06470	COG2409	Drug exporters of the RND superfamily
Athai_06480	COG2409	Drug exporters of the RND superfamily
Athai_06490	COG2197	response regulator
Athai_06500	COG2030	dehydratase
Athai_06510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Athai_06520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Athai_06530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Athai_06540	COG2815	serine threonine protein kinase
Athai_06540	COG0515	serine threonine protein kinase
Athai_06550	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Athai_06550	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Athai_06560	COG1473	amidohydrolase
Athai_06560	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Athai_06620	COG4770	biotin carboxylase activity
Athai_06650	COG1191	sigma factor activity
Athai_06660	COG2172	sigma factor antagonist activity
Athai_06740	COG1131	(ABC) transporter
Athai_06750	COG1725	Transcriptional regulator
Athai_06810	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_06810	COG0604	alcohol dehydrogenase
Athai_06810	COG3321	synthase
Athai_06820	COG2814	Major facilitator Superfamily
Athai_06840	COG0488	(ABC) transporter
Athai_06940	COG0567	Dehydrogenase, E1 component
Athai_06940	COG0508	dehydrogenase complex catalyzes the overall conversion of
Athai_06960	COG1131	(ABC) transporter
Athai_06970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Athai_06990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Athai_07060	COG0745	RESPONSE REGULATOR receiver
Athai_07070	COG2205	protein histidine kinase activity
Athai_07090	COG1609	Transcriptional regulator
Athai_07120	COG4209	transmembrane transport
Athai_07150	COG0673	inositol 2-dehydrogenase activity
Athai_07220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Athai_07240	COG1285	pathogenesis
Athai_07250	COG1522	sequence-specific DNA binding
Athai_07270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Athai_07290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Athai_07330	COG1131	(ABC) transporter
Athai_07360	COG2197	response regulator
Athai_07370	COG2318	DinB family
Athai_07390	COG1228	amidohydrolase
Athai_07420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Athai_07450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Athai_07460	COG2197	response regulator
Athai_07470	COG4585	Histidine kinase
Athai_07500	COG0730	response to heat
Athai_07510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Athai_07510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Athai_07630	COG1674	ftsk spoiiie
Athai_07640	COG1674	ftsk spoiiie
Athai_07910	COG1408	metallophosphoesterase
Athai_07920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Athai_07990	COG1136	(ABC) transporter
Athai_08030	COG0604	alcohol dehydrogenase
Athai_08030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Athai_08030	COG3321	synthase
Athai_08030	COG4221	oxidoreductase activity
Athai_08040	COG1376	ErfK ybiS ycfS ynhG family protein
Athai_08200	COG0714	Associated with various cellular activities
Athai_08240	COG2186	Transcriptional regulator
Athai_08250	COG2807	transmembrane transport
Athai_08260	COG0745	RESPONSE REGULATOR receiver
Athai_08270	COG5002	protein histidine kinase activity
Athai_08270	COG5000	phosphorelay sensor kinase activity
Athai_08280	COG5401	PFAM Sporulation and spore germination
Athai_08300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Athai_08320	COG0435	Glutathione S-transferase
Athai_08350	COG0653	protein targeting
Athai_08390	COG1324	tolerance protein
Athai_08420	COG1799	cell septum assembly
Athai_08440	COG1131	(ABC) transporter
Athai_08500	COG1012	belongs to the aldehyde dehydrogenase family
Athai_08530	COG3483	tryptophan 2,3-dioxygenase activity
Athai_08540	COG0515	serine threonine protein kinase
Athai_08560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Athai_08570	COG2884	Cell division ATP-binding protein ftsE
Athai_08580	COG2177	Part of the ABC transporter FtsEX involved in
Athai_08590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Athai_08690	COG0745	RESPONSE REGULATOR receiver
Athai_08700	COG5002	protein histidine kinase activity
Athai_08720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Athai_08730	COG1678	Uncharacterized ACR, COG1678
Athai_08800	COG0702	epimerase
Athai_08820	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_08830	COG1846	Transcriptional regulator
Athai_08960	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Athai_08970	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Athai_09020	COG1269	ATP hydrolysis coupled proton transport
Athai_09090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Athai_09100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Athai_09110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Athai_09120	COG0508	dehydrogenase complex catalyzes the overall conversion of
Athai_09120	COG0022	dehydrogenase e1 component
Athai_09130	COG0508	dehydrogenase complex catalyzes the overall conversion of
Athai_09170	COG1309	transcriptional regulator
Athai_09220	COG0667	Aldo Keto reductase
Athai_09410	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_09430	COG3903	Transcriptional regulator
Athai_09430	COG3629	intracellular signal transduction
Athai_09450	COG3903	Transcriptional regulator
Athai_09450	COG3629	intracellular signal transduction
Athai_09470	COG1335	isochorismatase
Athai_09540	COG2197	response regulator
Athai_09550	COG0596	Alpha beta hydrolase
Athai_09610	COG1132	(ABC) transporter
Athai_09650	COG2197	response regulator
Athai_09690	COG0477	Major facilitator Superfamily
Athai_09710	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_09860	COG1918	ferrous iron import across plasma membrane
Athai_09860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Athai_10010	COG0183	Belongs to the thiolase family
Athai_10030	COG1486	melibiose metabolic process
Athai_10040	COG1307	EDD domain protein, DegV family
Athai_10090	COG0667	Aldo Keto reductase
Athai_10100	COG4166	transmembrane transport
Athai_10170	COG0583	DNA-binding transcription factor activity
Athai_10210	COG0596	Alpha beta hydrolase
Athai_10310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Athai_10320	COG0022	dehydrogenase e1 component
Athai_10330	COG0508	dehydrogenase complex catalyzes the overall conversion of
Athai_10340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Athai_10360	COG2814	Major facilitator Superfamily
Athai_10380	COG0640	Transcriptional regulator
Athai_10390	COG0477	Major facilitator Superfamily
Athai_10570	COG2409	Drug exporters of the RND superfamily
Athai_10580	COG1309	transcriptional regulator
Athai_10610	COG1140	nitrate reductase beta subunit
Athai_10660	COG1309	transcriptional regulator
Athai_10670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Athai_10670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Athai_10740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Athai_10760	COG2188	Transcriptional regulator
Athai_10770	COG0477	Major facilitator Superfamily
Athai_10810	COG5001	Diguanylate cyclase
Athai_10810	COG3300	MHYT domain
Athai_11030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Athai_11060	COG3458	cephalosporin-C deacetylase activity
Athai_11090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Athai_11120	COG1376	ErfK ybiS ycfS ynhG family protein
Athai_11130	COG1584	GPR1 FUN34 yaaH family protein
Athai_11150	COG0860	N-Acetylmuramoyl-L-alanine amidase
Athai_11160	COG2706	6-phosphogluconolactonase activity
Athai_11180	COG4585	Histidine kinase
Athai_11190	COG1404	Belongs to the peptidase S8 family
Athai_11280	COG1674	ftsk spoiiie
Athai_11320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Athai_11360	COG2197	response regulator
Athai_11370	COG1716	ATPase activity
Athai_11400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Athai_11420	COG1228	amidohydrolase
Athai_11430	COG4608	Belongs to the ABC transporter superfamily
Athai_11440	COG0444	Belongs to the ABC transporter superfamily
Athai_11450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_11460	COG0601	transmembrane transport
Athai_11470	COG0747	negative chemotaxis
Athai_11480	COG1396	sequence-specific DNA binding
Athai_11500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Athai_11570	COG3336	cytochrome c oxidase
Athai_11580	COG2318	DinB family
Athai_11620	COG2271	Major facilitator Superfamily
Athai_11630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Athai_11710	COG0105	UTP biosynthetic process
Athai_11740	COG0702	epimerase
Athai_11790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Athai_11840	COG4552	Acetyltransferase involved in intracellular survival and related
Athai_11850	COG0515	serine threonine protein kinase
Athai_11860	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Athai_11890	COG2119	membrane
Athai_11930	COG2135	peptidase activity
Athai_12030	COG0514	ATP-dependent DNA helicase (RecQ)
Athai_12070	COG0583	DNA-binding transcription factor activity
Athai_12130	COG0544	peptidyl-prolyl cis-trans isomerase activity
Athai_12140	COG0740	serine-type endopeptidase activity
Athai_12150	COG0740	serine-type endopeptidase activity
Athai_12160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Athai_12210	COG0525	valine-tRNA ligase activity
Athai_12220	COG0285	dihydrofolate synthase activity
Athai_12270	COG0673	inositol 2-dehydrogenase activity
Athai_12310	COG0673	inositol 2-dehydrogenase activity
Athai_12350	COG0640	Transcriptional regulator
Athai_12370	COG0698	ribose 5-phosphate isomerase
Athai_12390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Athai_12400	COG2376	Dihydroxyacetone kinase
Athai_12410	COG0698	ribose 5-phosphate isomerase
Athai_12420	COG1070	Carbohydrate kinase
Athai_12450	COG0242	peptide deformylase activity
Athai_12490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Athai_12510	COG1070	Carbohydrate kinase
Athai_12520	COG0588	phosphoglycerate mutase activity
Athai_12530	COG1653	transport
Athai_12540	COG1175	transmembrane transport
Athai_12560	COG3842	ATPase activity
Athai_12570	COG3842	ATPase activity
Athai_12580	COG1349	DNA-binding transcription factor activity
Athai_12610	COG3345	alpha-galactosidase
Athai_12660	COG2205	protein histidine kinase activity
Athai_12670	COG0745	RESPONSE REGULATOR receiver
Athai_12690	COG0180	Tryptophanyl-tRNA synthetase
Athai_12740	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Athai_12750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Athai_12760	COG0799	negative regulation of ribosome biogenesis
Athai_12800	COG1555	photosystem II stabilization
Athai_12830	COG0268	Binds directly to 16S ribosomal RNA
Athai_12850	COG0481	GTPase activity
Athai_12890	COG2226	methyltransferase
Athai_12910	COG1309	transcriptional regulator
Athai_12970	COG1024	Enoyl-CoA hydratase
Athai_13040	COG1420	regulation of RNA biosynthetic process
Athai_13050	COG0484	heat shock protein binding
Athai_13060	COG0484	heat shock protein binding
Athai_13080	COG0537	adenosine 5'-monophosphoramidase activity
Athai_13120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Athai_13160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Athai_13180	COG0714	Associated with various cellular activities
Athai_13220	COG0667	Aldo Keto reductase
Athai_13250	COG1381	Involved in DNA repair and RecF pathway recombination
Athai_13260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Athai_13290	COG1309	transcriptional regulator
Athai_13300	COG0604	alcohol dehydrogenase
Athai_13460	COG2192	nodulation
Athai_13490	COG3547	Transposase (IS116 IS110 IS902 family)
Athai_13500	COG3547	Transposase (IS116 IS110 IS902 family)
Athai_13590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Athai_13610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Athai_13620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Athai_13670	COG1233	COG1233 Phytoene dehydrogenase and related
Athai_13770	COG0165	Argininosuccinate lyase
Athai_13780	COG0492	ferredoxin-NADP+ reductase activity
Athai_13790	COG2274	protein secretion by the type I secretion system
Athai_13800	COG1132	(ABC) transporter
Athai_13820	COG0215	cysteine-tRNA ligase activity
Athai_14000	COG3251	PFAM MbtH domain protein
Athai_14030	COG3433	isochorismatase activity
Athai_14030	COG2226	methyltransferase
Athai_14030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Athai_14100	COG4552	Acetyltransferase involved in intracellular survival and related
Athai_14140	COG2197	response regulator
Athai_14150	COG4585	Histidine kinase
Athai_14180	COG0667	Aldo Keto reductase
Athai_14260	COG0596	Alpha beta hydrolase
Athai_14380	COG2197	response regulator
Athai_14450	COG4989	oxidoreductase activity
Athai_14460	COG0667	Aldo Keto reductase
Athai_14480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Athai_14600	COG1595	DNA-templated transcription, initiation
Athai_14640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Athai_14770	COG3511	phospholipase C
Athai_14780	COG0604	alcohol dehydrogenase
Athai_14820	COG1733	regulation of RNA biosynthetic process
Athai_14850	COG0823	Involved in the tonB-independent uptake of proteins
Athai_14850	COG4946	Tricorn protease homolog
Athai_14850	COG1506	peptidase
Athai_14880	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_14900	COG2197	response regulator
Athai_14910	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_14930	COG1233	COG1233 Phytoene dehydrogenase and related
Athai_14980	COG0583	DNA-binding transcription factor activity
Athai_14990	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_15000	COG0477	Major facilitator Superfamily
Athai_15020	COG3903	Transcriptional regulator
Athai_15020	COG3629	intracellular signal transduction
Athai_15060	COG2409	Drug exporters of the RND superfamily
Athai_15160	COG2068	MobA-Related Protein
Athai_15220	COG2326	polyphosphate kinase activity
Athai_15270	COG2210	Belongs to the sulfur carrier protein TusA family
Athai_15280	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Athai_15320	COG1063	alcohol dehydrogenase
Athai_15370	COG0589	response to stress
Athai_15390	COG0516	GMP reductase activity
Athai_15420	COG0549	Belongs to the carbamate kinase family
Athai_15460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Athai_15470	COG0589	response to stress
Athai_15480	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Athai_15570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_15580	COG0601	transmembrane transport
Athai_15590	COG0747	negative chemotaxis
Athai_15600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Athai_15610	COG2205	protein histidine kinase activity
Athai_15620	COG0745	RESPONSE REGULATOR receiver
Athai_15630	COG1131	(ABC) transporter
Athai_15640	COG1131	(ABC) transporter
Athai_15670	COG0513	Belongs to the DEAD box helicase family
Athai_15710	COG4941	Belongs to the sigma-70 factor family
Athai_15770	COG0745	RESPONSE REGULATOR receiver
Athai_15780	COG0745	RESPONSE REGULATOR receiver
Athai_15790	COG2205	protein histidine kinase activity
Athai_15800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Athai_15810	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Athai_15820	COG1181	Belongs to the D-alanine--D-alanine ligase family
Athai_15860	COG0656	L-ascorbic acid biosynthetic process
Athai_15900	COG1131	(ABC) transporter
Athai_15930	COG1309	transcriptional regulator
Athai_15940	COG1131	(ABC) transporter
Athai_15960	COG0657	acetylesterase activity
Athai_15970	COG3347	Dehydrogenase
Athai_15970	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_15980	COG1309	transcriptional regulator
Athai_16010	COG0038	chloride channel
Athai_16170	COG0437	4 iron, 4 sulfur cluster binding
Athai_16180	COG3383	formate dehydrogenase (NAD+) activity
Athai_16180	COG0243	molybdopterin cofactor binding
Athai_16210	COG0028	Belongs to the TPP enzyme family
Athai_16220	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_16240	COG0247	lactate metabolic process
Athai_16240	COG0277	FAD linked oxidase domain protein
Athai_16250	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_16270	COG0477	Major facilitator Superfamily
Athai_16280	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_16380	COG0709	Synthesizes selenophosphate from selenide and ATP
Athai_16480	COG0640	Transcriptional regulator
Athai_16540	COG0702	epimerase
Athai_16590	COG1942	4-Oxalocrotonate Tautomerase
Athai_16700	COG2197	response regulator
Athai_16780	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_16800	COG1414	Transcriptional regulator
Athai_16810	COG1129	ABC transporter
Athai_16820	COG1172	Belongs to the binding-protein-dependent transport system permease family
Athai_16850	COG4552	Acetyltransferase involved in intracellular survival and related
Athai_16870	COG2226	methyltransferase
Athai_16940	COG1595	DNA-templated transcription, initiation
Athai_16960	COG1595	DNA-templated transcription, initiation
Athai_16980	COG2226	methyltransferase
Athai_17010	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Athai_17060	COG0745	RESPONSE REGULATOR receiver
Athai_17110	COG0778	Nitroreductase
Athai_17120	COG1609	Transcriptional regulator
Athai_17130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Athai_17140	COG1869	D-ribose catabolic process
Athai_17160	COG2182	Extracellular solute-binding protein
Athai_17170	COG1175	transmembrane transport
Athai_17180	COG0395	ABC-type sugar transport system, permease component
Athai_17190	COG3119	arylsulfatase activity
Athai_17240	COG3119	arylsulfatase activity
Athai_17280	COG1134	teichoic acid transport
Athai_17300	COG1309	transcriptional regulator
Athai_17330	COG0215	cysteine-tRNA ligase activity
Athai_17380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Athai_17410	COG1120	ATPase activity
Athai_17430	COG2197	response regulator
Athai_17470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Athai_17520	COG2986	histidine ammonia-lyase
Athai_17600	COG4941	Belongs to the sigma-70 factor family
Athai_17610	COG3795	YCII-related domain
Athai_17680	COG2197	response regulator
Athai_17700	COG1309	transcriptional regulator
Athai_17760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Athai_17780	COG0438	transferase activity, transferring glycosyl groups
Athai_17800	COG3858	chitin binding
Athai_17800	COG1388	LysM domain
Athai_17810	COG1215	transferase activity, transferring glycosyl groups
Athai_17860	COG2197	response regulator
Athai_17880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Athai_17900	COG2814	Major facilitator Superfamily
Athai_17910	COG4977	sequence-specific DNA binding
Athai_17920	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_17950	COG1136	(ABC) transporter
Athai_17950	COG0577	efflux transmembrane transporter activity
Athai_18040	COG3340	Belongs to the peptidase S51 family
Athai_18110	COG0667	Aldo Keto reductase
Athai_18260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Athai_18270	COG4266	Belongs to the allantoicase family
Athai_18280	COG0477	Major facilitator Superfamily
Athai_18340	COG1175	transmembrane transport
Athai_18350	COG0395	ABC-type sugar transport system, permease component
Athai_18370	COG1846	Transcriptional regulator
Athai_18380	COG3458	cephalosporin-C deacetylase activity
Athai_18420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Athai_18430	COG1609	Transcriptional regulator
Athai_18470	COG0714	Associated with various cellular activities
Athai_18530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Athai_18600	COG1609	Transcriptional regulator
Athai_18610	COG1472	Belongs to the glycosyl hydrolase 3 family
Athai_18620	COG1653	transport
Athai_18640	COG1175	transmembrane transport
Athai_18660	COG0477	Major facilitator Superfamily
Athai_18710	COG1063	alcohol dehydrogenase
Athai_18730	COG0156	8-amino-7-oxononanoate synthase activity
Athai_18770	COG1609	Transcriptional regulator
Athai_18780	COG3250	beta-galactosidase activity
Athai_18800	COG1175	transmembrane transport
Athai_18820	COG3940	Belongs to the glycosyl hydrolase 43 family
Athai_18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Athai_18840	COG1131	(ABC) transporter
Athai_18910	COG1595	DNA-templated transcription, initiation
Athai_19000	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Athai_19030	COG0387	Pfam Sodium calcium exchanger
Athai_19040	COG0121	glutamine amidotransferase
Athai_19050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Athai_19060	COG2226	methyltransferase
Athai_19140	COG0456	acetyltransferase
Athai_19160	COG1609	Transcriptional regulator
Athai_19170	COG0629	single-stranded DNA binding
Athai_19200	COG0501	Belongs to the peptidase M48B family
Athai_19210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Athai_19220	COG1994	Peptidase M50
Athai_19240	COG1793	dna ligase
Athai_19260	COG1797	cobyrinic acid a,c-diamide synthase activity
Athai_19300	COG1648	precorrin-2 dehydrogenase activity
Athai_19300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Athai_19310	COG0456	acetyltransferase
Athai_19320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Athai_19340	COG5285	phytanoyl-CoA dioxygenase
Athai_19350	COG3387	PFAM Glycoside hydrolase 15-related
Athai_19360	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Athai_19470	COG0583	DNA-binding transcription factor activity
Athai_19480	COG3360	Dodecin
Athai_19580	COG0515	serine threonine protein kinase
Athai_19600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Athai_19650	COG1278	Cold shock
Athai_19670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Athai_19700	COG1213	nucleotidyl transferase
Athai_19700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Athai_19730	COG4585	Histidine kinase
Athai_19790	COG1472	Belongs to the glycosyl hydrolase 3 family
Athai_19800	COG2197	response regulator
Athai_19810	COG4585	Histidine kinase
Athai_19830	COG2409	Drug exporters of the RND superfamily
Athai_19870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Athai_19880	COG1414	Transcriptional regulator
Athai_19900	COG2226	methyltransferase
Athai_19920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Athai_19930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Athai_20010	COG1595	DNA-templated transcription, initiation
Athai_20040	COG1131	(ABC) transporter
Athai_20060	COG1556	Lactate utilization protein
Athai_20070	COG1139	Iron-sulfur cluster binding protein
Athai_20080	COG0247	lactate metabolic process
Athai_20110	COG3618	amidohydrolase
Athai_20120	COG0179	Fumarylacetoacetate (FAA) hydrolase
Athai_20130	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_20150	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_20160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Athai_20190	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Athai_20300	COG3386	PFAM SMP-30 Gluconolaconase
Athai_20320	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_20340	COG1175	transmembrane transport
Athai_20350	COG0395	ABC-type sugar transport system, permease component
Athai_20430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Athai_20440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Athai_20460	COG1609	Transcriptional regulator
Athai_20480	COG1129	ABC transporter
Athai_20490	COG1172	Belongs to the binding-protein-dependent transport system permease family
Athai_20500	COG1515	deoxyribonuclease V activity
Athai_20510	COG2226	methyltransferase
Athai_20530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Athai_20560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Athai_20600	COG2183	response to ionizing radiation
Athai_20710	COG2860	membrane
Athai_20740	COG0346	lactoylglutathione lyase activity
Athai_20750	COG0183	Belongs to the thiolase family
Athai_20800	COG1136	(ABC) transporter
Athai_20860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Athai_20880	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Athai_20880	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Athai_20910	COG1404	Belongs to the peptidase S8 family
Athai_20920	COG4260	virion core protein, lumpy skin disease virus
Athai_20960	COG0010	Belongs to the arginase family
Athai_20970	COG2902	Dehydrogenase
Athai_21000	COG1271	oxidase subunit
Athai_21010	COG1294	oxidase, subunit
Athai_21020	COG4988	ABC transporter
Athai_21030	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Athai_21040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Athai_21070	COG0789	Transcriptional regulator
Athai_21090	COG1309	transcriptional regulator
Athai_21120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Athai_21130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Athai_21180	COG0366	Alpha amylase catalytic
Athai_21190	COG0366	Alpha amylase catalytic
Athai_21200	COG0366	Alpha amylase catalytic
Athai_21250	COG0395	ABC-type sugar transport system, permease component
Athai_21260	COG1175	transmembrane transport
Athai_21280	COG1940	carbohydrate kinase activity
Athai_21280	COG1846	Transcriptional regulator
Athai_21300	COG1725	Transcriptional regulator
Athai_21310	COG1131	(ABC) transporter
Athai_21360	COG1132	(ABC) transporter
Athai_21380	COG1609	Transcriptional regulator
Athai_21410	COG1119	ATPase activity
Athai_21450	COG0110	maltose O-acetyltransferase activity
Athai_21470	COG3979	chitinase
Athai_21550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Athai_21610	COG0482	sulfurtransferase activity
Athai_21620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Athai_21640	COG0583	DNA-binding transcription factor activity
Athai_21660	COG0667	Aldo Keto reductase
Athai_21720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Athai_21790	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Athai_21800	COG0154	amidase activity
Athai_21810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Athai_21850	COG2133	pyrroloquinoline quinone binding
Athai_21900	COG5001	Diguanylate cyclase
Athai_21900	COG3300	MHYT domain
Athai_21910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Athai_21920	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_22000	COG0129	dihydroxy-acid dehydratase activity
Athai_22020	COG0028	Belongs to the TPP enzyme family
Athai_22030	COG0440	acetolactate synthase activity
Athai_22040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Athai_22060	COG0473	3-isopropylmalate dehydrogenase activity
Athai_22100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Athai_22110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Athai_22120	COG0450	alkyl hydroperoxide reductase
Athai_22130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Athai_22150	COG1131	(ABC) transporter
Athai_22160	COG4585	Histidine kinase
Athai_22170	COG2197	response regulator
Athai_22190	COG0179	Fumarylacetoacetate (FAA) hydrolase
Athai_22200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Athai_22210	COG0546	phosphoglycolate phosphatase activity
Athai_22220	COG2226	methyltransferase
Athai_22260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Athai_22270	COG0066	3-isopropylmalate dehydratase activity
Athai_22280	COG0494	nUDIX hydrolase
Athai_22280	COG0406	alpha-ribazole phosphatase activity
Athai_22290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Athai_22320	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Athai_22330	COG0626	cystathionine gamma-synthase activity
Athai_22360	COG0589	response to stress
Athai_22430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Athai_22460	COG0742	ribosomal rna small subunit methyltransferase
Athai_22470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Athai_22500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Athai_22510	COG0416	fatty acid biosynthetic process
Athai_22520	COG0571	ribonuclease III activity
Athai_22550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Athai_22560	COG3548	integral membrane protein
Athai_22570	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_22590	COG1254	Belongs to the acylphosphatase family
Athai_22640	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_22710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Athai_22850	COG0442	prolyl-tRNA aminoacylation
Athai_22870	COG0596	Alpha beta hydrolase
Athai_22890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_22900	COG0601	transmembrane transport
Athai_22910	COG4166	transmembrane transport
Athai_22930	COG0444	Belongs to the ABC transporter superfamily
Athai_22940	COG4608	Belongs to the ABC transporter superfamily
Athai_22950	COG0228	four-way junction DNA binding
Athai_22960	COG1837	Belongs to the UPF0109 family
Athai_22970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Athai_22980	COG0336	Belongs to the RNA methyltransferase TrmD family
Athai_22990	COG0335	large ribosomal subunit rRNA binding
Athai_23000	COG0681	Belongs to the peptidase S26 family
Athai_23010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Athai_23040	COG0792	nuclease activity
Athai_23150	COG0052	Belongs to the universal ribosomal protein uS2 family
Athai_23160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Athai_23170	COG0528	UMP kinase activity
Athai_23180	COG0233	cytoplasmic translational termination
Athai_23190	COG0575	Belongs to the CDS family
Athai_23200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Athai_23290	COG0277	FAD linked oxidase domain protein
Athai_23320	COG2076	Multidrug Resistance protein
Athai_23340	COG0750	zinc metalloprotease
Athai_23350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Athai_23380	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Athai_23420	COG1012	belongs to the aldehyde dehydrogenase family
Athai_23440	COG0514	ATP-dependent DNA helicase (RecQ)
Athai_23560	COG0779	Required for maturation of 30S ribosomal subunits
Athai_23590	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Athai_23650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Athai_23700	COG1234	tRNA 3'-trailer cleavage
Athai_23710	COG0534	Mate efflux family protein
Athai_23740	COG0477	Major facilitator Superfamily
Athai_23750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Athai_23770	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Athai_23780	COG1185	polyribonucleotide nucleotidyltransferase activity
Athai_23790	COG0612	Peptidase, M16
Athai_23800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Athai_23830	COG3214	Protein conserved in bacteria
Athai_23880	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Athai_23890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Athai_23900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Athai_23910	COG3619	membrane
Athai_23960	COG1674	ftsk spoiiie
Athai_23980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Athai_24000	COG1546	Belongs to the CinA family
Athai_24000	COG1058	Belongs to the CinA family
Athai_24010	COG1396	sequence-specific DNA binding
Athai_24020	COG1842	Phage shock protein A
Athai_24050	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
Athai_24060	COG0456	acetyltransferase
Athai_24090	COG1201	RNA secondary structure unwinding
Athai_24130	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Athai_24140	COG2137	regulation of response to DNA damage stimulus
Athai_24150	COG1418	mRNA catabolic process
Athai_24180	COG0438	transferase activity, transferring glycosyl groups
Athai_24190	COG0765	amino acid transport
Athai_24200	COG0765	amino acid transport
Athai_24210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Athai_24220	COG1126	abc transporter atp-binding protein
Athai_24230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Athai_24240	COG0142	geranyltranstransferase activity
Athai_24300	COG0339	signal peptide processing
Athai_24350	COG0587	DNA-directed DNA polymerase activity
Athai_24360	COG0587	DNA-directed DNA polymerase activity
Athai_24370	COG2124	cytochrome p450
Athai_24420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Athai_24460	COG0714	Associated with various cellular activities
Athai_24470	COG0714	Associated with various cellular activities
Athai_24480	COG0495	leucyl-tRNA aminoacylation
Athai_24500	COG3442	glutamine amidotransferase
Athai_24510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Athai_24520	COG2001	Belongs to the MraZ family
Athai_24530	COG0275	rRNA processing
Athai_24550	COG0768	penicillin binding
Athai_24560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Athai_24580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Athai_24590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Athai_24610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Athai_24620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Athai_24630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Athai_24640	COG2318	DinB family
Athai_24680	COG1799	cell septum assembly
Athai_24700	COG3599	regulation of cell shape
Athai_24720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Athai_24730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Athai_24790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Athai_24800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Athai_24830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Athai_24840	COG0107	imidazoleglycerol-phosphate synthase activity
Athai_24850	COG2364	Membrane
Athai_24860	COG0436	Aminotransferase
Athai_24870	COG1132	(ABC) transporter
Athai_24880	COG1132	(ABC) transporter
Athai_24920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Athai_24960	COG0133	tryptophan synthase activity
Athai_24970	COG0159	tryptophan synthase activity
Athai_24990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Athai_25050	COG0070	glutamate synthase
Athai_25050	COG0067	glutamate synthase
Athai_25050	COG0069	glutamate synthase activity
Athai_25130	COG1404	Belongs to the peptidase S8 family
Athai_25210	COG1946	Acyl-CoA thioesterase
Athai_25340	COG0765	amino acid transport
Athai_25350	COG1126	abc transporter atp-binding protein
Athai_25390	COG0531	amino acid
Athai_25400	COG2362	D-Aminopeptidase
Athai_25430	COG2226	methyltransferase
Athai_25460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Athai_25460	COG0237	dephospho-CoA kinase activity
Athai_25470	COG1131	(ABC) transporter
Athai_25490	COG4585	Histidine kinase
Athai_25500	COG2197	response regulator
Athai_25530	COG2329	Antibiotic biosynthesis monooxygenase
Athai_25550	COG0791	NLP P60 protein
Athai_25560	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_25600	COG1217	gtp-binding protein TYPA
Athai_25640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Athai_25650	COG1162	GTPase activity
Athai_25680	COG0322	excinuclease ABC activity
Athai_25690	COG1660	Displays ATPase and GTPase activities
Athai_25710	COG1481	regulation of sporulation
Athai_25720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Athai_25730	COG0126	phosphoglycerate kinase activity
Athai_25740	COG0149	triose-phosphate isomerase activity
Athai_25770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Athai_25790	COG0363	glucosamine-6-phosphate deaminase activity
Athai_25820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Athai_25840	COG0109	protoheme IX farnesyltransferase activity
Athai_25870	COG3875	lactate racemase activity
Athai_25880	COG1063	alcohol dehydrogenase
Athai_25900	COG1612	heme a metabolic process
Athai_25960	COG0396	ATPase activity
Athai_25970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Athai_25980	COG0822	iron-sulfur transferase activity
Athai_25990	COG2151	metal-sulfur cluster biosynthetic enzyme
Athai_26020	COG0488	(ABC) transporter
Athai_26100	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_26140	COG3547	Transposase (IS116 IS110 IS902 family)
Athai_26150	COG3547	Transposase (IS116 IS110 IS902 family)
Athai_26160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Athai_26190	COG4941	Belongs to the sigma-70 factor family
Athai_26210	COG1765	OsmC-like protein
Athai_26230	COG0395	ABC-type sugar transport system, permease component
Athai_26240	COG1175	transmembrane transport
Athai_26260	COG1070	Carbohydrate kinase
Athai_26290	COG1609	Transcriptional regulator
Athai_26300	COG0039	L-malate dehydrogenase activity
Athai_26310	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_26320	COG1793	dna ligase
Athai_26330	COG0477	Major facilitator Superfamily
Athai_26380	COG0419	ATPase involved in DNA repair
Athai_26390	COG0420	3'-5' exonuclease activity
Athai_26420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Athai_26440	COG0154	amidase activity
Athai_26460	COG3473	Maleate cis-trans isomerase
Athai_26480	COG1802	Transcriptional regulator
Athai_26540	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Athai_26560	COG3022	response to hydroperoxide
Athai_26580	COG3842	ATPase activity
Athai_26590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Athai_26650	COG2197	response regulator
Athai_26660	COG4585	Histidine kinase
Athai_26690	COG1175	transmembrane transport
Athai_26700	COG1653	transport
Athai_26730	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_26740	COG0596	Alpha beta hydrolase
Athai_26780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Athai_26830	COG4565	transcriptional regulatory protein
Athai_26840	COG3290	protein histidine kinase activity
Athai_26860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Athai_26900	COG1595	DNA-templated transcription, initiation
Athai_26910	COG1649	PFAM Uncharacterised BCR, COG1649
Athai_26920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Athai_26940	COG2814	Major facilitator Superfamily
Athai_26960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Athai_26970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Athai_26980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Athai_26990	COG5001	Diguanylate cyclase
Athai_27020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Athai_27040	COG5002	protein histidine kinase activity
Athai_27050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Athai_27060	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_27080	COG2822	iron ion transport
Athai_27100	COG3511	phospholipase C
Athai_27160	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_27190	COG1902	pentaerythritol trinitrate reductase activity
Athai_27190	COG0446	pyridine nucleotide-disulphide oxidoreductase
Athai_27220	COG1940	carbohydrate kinase activity
Athai_27290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Athai_27320	COG0589	response to stress
Athai_27340	COG1695	Transcriptional regulator
Athai_27370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Athai_27390	COG2188	Transcriptional regulator
Athai_27540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Athai_27550	COG1560	Kdo2-lipid A biosynthetic process
Athai_27560	COG0438	transferase activity, transferring glycosyl groups
Athai_27580	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Athai_27590	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Athai_27610	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Athai_27620	COG0632	four-way junction helicase activity
Athai_27630	COG2255	four-way junction helicase activity
Athai_27660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Athai_27670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Athai_27690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Athai_27730	COG0124	histidyl-tRNA synthetase
Athai_27740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Athai_27760	COG4585	Histidine kinase
Athai_27770	COG2197	response regulator
Athai_27830	COG2376	Dihydroxyacetone kinase
Athai_27890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Athai_27940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Athai_27950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Athai_27970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Athai_27990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Athai_28000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Athai_28020	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Athai_28030	COG0540	Belongs to the ATCase OTCase family
Athai_28040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Athai_28050	COG0505	Belongs to the CarA family
Athai_28070	COG0167	dihydroorotate dehydrogenase activity
Athai_28080	COG0284	orotidine-5'-phosphate decarboxylase activity
Athai_28090	COG0194	GDP metabolic process
Athai_28100	COG0194	GDP metabolic process
Athai_28110	COG1758	RNA polymerase activity
Athai_28130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Athai_28150	COG0242	peptide deformylase activity
Athai_28160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Athai_28190	COG2814	Major facilitator Superfamily
Athai_28230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Athai_28270	COG4821	SIS domain
Athai_28280	COG2188	Transcriptional regulator
Athai_28340	COG1716	ATPase activity
Athai_28380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Athai_28380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Athai_28390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Athai_28390	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Athai_28500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Athai_28530	COG1131	(ABC) transporter
Athai_28610	COG2318	DinB family
Athai_28660	COG0477	Major facilitator Superfamily
Athai_28680	COG3795	YCII-related domain
Athai_28690	COG4941	Belongs to the sigma-70 factor family
Athai_28700	COG2197	response regulator
Athai_28730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Athai_28740	COG2890	protein-(glutamine-N5) methyltransferase activity
Athai_28790	COG1132	(ABC) transporter
Athai_28800	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Athai_28820	COG4974	Belongs to the 'phage' integrase family
Athai_28920	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Athai_28930	COG4988	ABC transporter
Athai_28940	COG1294	oxidase, subunit
Athai_28950	COG1271	oxidase subunit
Athai_28980	COG2197	response regulator
Athai_29030	COG0443	Heat shock 70 kDa protein
Athai_29040	COG0584	glycerophosphoryl diester phosphodiesterase
Athai_29060	COG1435	thymidine kinase activity
Athai_29070	COG1752	Esterase of the alpha-beta hydrolase superfamily
Athai_29080	COG1960	acyl-CoA dehydrogenase activity
Athai_29100	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Athai_29110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Athai_29170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Athai_29180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Athai_29200	COG0604	alcohol dehydrogenase
Athai_29220	COG0406	alpha-ribazole phosphatase activity
Athai_29250	COG1960	acyl-CoA dehydrogenase activity
Athai_29280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Athai_29340	COG1960	acyl-CoA dehydrogenase activity
Athai_29360	COG1846	Transcriptional regulator
Athai_29380	COG1554	hydrolase, family 65, central catalytic
Athai_29420	COG1191	sigma factor activity
Athai_29470	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Athai_29490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Athai_29560	COG0725	ABC transporter, periplasmic molybdate-binding protein
Athai_29590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Athai_29610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Athai_29620	COG1733	regulation of RNA biosynthetic process
Athai_29630	COG3842	ATPase activity
Athai_29640	COG0395	ABC-type sugar transport system, permease component
Athai_29660	COG2182	Extracellular solute-binding protein
Athai_29790	COG0702	epimerase
Athai_29820	COG0667	Aldo Keto reductase
Athai_29860	COG0583	DNA-binding transcription factor activity
Athai_29890	COG1172	Belongs to the binding-protein-dependent transport system permease family
Athai_29900	COG1879	ABC-type sugar transport system periplasmic component
Athai_29990	COG2197	response regulator
Athai_30020	COG0442	prolyl-tRNA aminoacylation
Athai_30050	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Athai_30060	COG1739	Uncharacterized protein family UPF0029
Athai_30080	COG0254	rRNA binding
Athai_30120	COG3250	beta-galactosidase activity
Athai_30150	COG3250	beta-galactosidase activity
Athai_30160	COG2814	Major facilitator Superfamily
Athai_30180	COG1414	Transcriptional regulator
Athai_30200	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_30210	COG1063	alcohol dehydrogenase
Athai_30220	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_30260	COG3511	phospholipase C
Athai_30270	COG3201	nicotinamide mononucleotide transporter
Athai_30290	COG1846	Transcriptional regulator
Athai_30310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Athai_30320	COG1053	succinate dehydrogenase
Athai_30340	COG0583	DNA-binding transcription factor activity
Athai_30360	COG1160	GTP binding
Athai_30380	COG4166	transmembrane transport
Athai_30400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_30410	COG0444	Belongs to the ABC transporter superfamily
Athai_30450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Athai_30460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Athai_30510	COG0504	CTP synthase activity
Athai_30530	COG0438	transferase activity, transferring glycosyl groups
Athai_30570	COG0497	DNA recombination
Athai_30580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Athai_30630	COG0647	UMP catabolic process
Athai_30670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Athai_30680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Athai_30690	COG0789	Transcriptional regulator
Athai_30700	COG0165	Argininosuccinate lyase
Athai_30720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Athai_30730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Athai_30740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Athai_30750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Athai_30760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Athai_30770	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Athai_30780	COG0463	Glycosyl transferase, family 2
Athai_30800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Athai_30800	COG0072	phenylalanine-tRNA ligase activity
Athai_30810	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Athai_30820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Athai_30830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Athai_30840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Athai_30850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Athai_30880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Athai_30890	COG0140	phosphoribosyl-ATP diphosphatase activity
Athai_30910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Athai_30920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Athai_30920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Athai_30940	COG0745	RESPONSE REGULATOR receiver
Athai_30960	COG2318	DinB family
Athai_31000	COG0805	protein transport
Athai_31010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Athai_31030	COG2378	regulation of single-species biofilm formation
Athai_31040	COG2378	regulation of single-species biofilm formation
Athai_31080	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Athai_31090	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Athai_31100	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Athai_31130	COG4122	O-methyltransferase activity
Athai_31150	COG1222	aaa ATPase
Athai_31170	COG1994	Peptidase M50
Athai_31170	COG0517	IMP dehydrogenase activity
Athai_31190	COG4585	Histidine kinase
Athai_31200	COG2197	response regulator
Athai_31210	COG1136	(ABC) transporter
Athai_31220	COG1136	(ABC) transporter
Athai_31220	COG0577	efflux transmembrane transporter activity
Athai_31250	COG1309	transcriptional regulator
Athai_31420	COG1674	ftsk spoiiie
Athai_31460	COG0464	growth
Athai_31510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Athai_31530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Athai_31540	COG1410	methionine synthase
Athai_31540	COG0646	methionine synthase
Athai_31580	COG0215	cysteine-tRNA ligase activity
Athai_31620	COG0588	phosphoglycerate mutase activity
Athai_31630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Athai_31640	COG0667	Aldo Keto reductase
Athai_31730	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Athai_31740	COG0352	thiamine-phosphate diphosphorylase activity
Athai_31750	COG0352	thiamine-phosphate diphosphorylase activity
Athai_31750	COG0351	phosphomethylpyrimidine kinase
Athai_31750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Athai_31860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Athai_31890	COG0702	epimerase
Athai_31960	COG1472	Belongs to the glycosyl hydrolase 3 family
Athai_31980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Athai_31990	COG2367	Beta-lactamase
Athai_32010	COG1309	transcriptional regulator
Athai_32030	COG1070	Carbohydrate kinase
Athai_32060	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Athai_32070	COG1716	ATPase activity
Athai_32170	COG1940	carbohydrate kinase activity
Athai_32180	COG0531	amino acid
Athai_32290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Athai_32320	COG1595	DNA-templated transcription, initiation
Athai_32370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Athai_32390	COG3469	chitinase activity
Athai_32490	COG0640	Transcriptional regulator
Athai_32550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Athai_32560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Athai_32630	COG1175	transmembrane transport
Athai_32700	COG0395	ABC-type sugar transport system, permease component
Athai_32710	COG1175	transmembrane transport
Athai_32730	COG2182	Extracellular solute-binding protein
Athai_32750	COG1609	Transcriptional regulator
Athai_32770	COG4977	sequence-specific DNA binding
Athai_32810	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Athai_32830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Athai_32850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Athai_32900	COG1228	amidohydrolase
Athai_32910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Athai_32940	COG1846	Transcriptional regulator
Athai_32950	COG4221	oxidoreductase activity
Athai_32980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Athai_32990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Athai_33000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Athai_33030	COG0395	ABC-type sugar transport system, permease component
Athai_33040	COG1175	transmembrane transport
Athai_33050	COG1653	transport
Athai_33110	COG3883	PFAM NLP P60 protein
Athai_33110	COG0791	NLP P60 protein
Athai_33140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Athai_33150	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Athai_33160	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_33190	COG0714	Associated with various cellular activities
Athai_33240	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Athai_33310	COG0697	spore germination
Athai_33350	COG2186	Transcriptional regulator
Athai_33390	COG4209	transmembrane transport
Athai_33400	COG0395	ABC-type sugar transport system, permease component
Athai_33430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Athai_33470	COG1595	DNA-templated transcription, initiation
Athai_33540	COG0823	Involved in the tonB-independent uptake of proteins
Athai_33550	COG0667	Aldo Keto reductase
Athai_33590	COG1175	transmembrane transport
Athai_33610	COG0366	Alpha amylase catalytic
Athai_33650	COG1119	ATPase activity
Athai_33690	COG0577	efflux transmembrane transporter activity
Athai_33690	COG1136	(ABC) transporter
Athai_33700	COG1511	domain protein
Athai_33720	COG0006	proline dipeptidase activity
Athai_33740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Athai_33870	COG0601	transmembrane transport
Athai_33880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_33890	COG0747	negative chemotaxis
Athai_33950	COG1960	acyl-CoA dehydrogenase activity
Athai_34010	COG0006	proline dipeptidase activity
Athai_34080	COG0412	Dienelactone hydrolase
Athai_34090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Athai_34120	COG1643	Atp-dependent helicase
Athai_34150	COG0179	Fumarylacetoacetate (FAA) hydrolase
Athai_34200	COG1063	alcohol dehydrogenase
Athai_34250	COG2188	Transcriptional regulator
Athai_34260	COG0673	inositol 2-dehydrogenase activity
Athai_34280	COG1082	Xylose isomerase domain protein TIM barrel
Athai_34290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Athai_34310	COG3718	enzyme involved in inositol metabolism
Athai_34320	COG3962	Belongs to the TPP enzyme family
Athai_34370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Athai_34390	COG3579	cysteine-type endopeptidase activity
Athai_34420	COG3253	May function as heme-dependent peroxidase
Athai_34430	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Athai_34440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Athai_34470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Athai_34490	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Athai_34510	COG0183	Belongs to the thiolase family
Athai_34520	COG1250	3-hydroxyacyl-CoA dehydrogenase
Athai_34520	COG1024	Enoyl-CoA hydratase
Athai_34570	COG0477	Major facilitator Superfamily
Athai_34580	COG1309	transcriptional regulator
Athai_34590	COG0604	alcohol dehydrogenase
Athai_34660	COG2205	protein histidine kinase activity
Athai_34670	COG0745	RESPONSE REGULATOR receiver
Athai_34680	COG0745	RESPONSE REGULATOR receiver
Athai_34740	COG3537	Alpha-1,2-mannosidase
Athai_34750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Athai_34760	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Athai_34770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Athai_34780	COG0747	negative chemotaxis
Athai_34790	COG0601	transmembrane transport
Athai_34800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_34810	COG0444	Belongs to the ABC transporter superfamily
Athai_34820	COG4608	Belongs to the ABC transporter superfamily
Athai_34830	COG4214	carbohydrate transport
Athai_34850	COG4213	ABC transporter substrate-binding protein
Athai_34860	COG1940	carbohydrate kinase activity
Athai_34870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Athai_34910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Athai_34920	COG0531	amino acid
Athai_34930	COG0569	domain protein
Athai_34980	COG0756	dUTP diphosphatase activity
Athai_35070	COG2313	pseudouridylate synthase activity
Athai_35100	COG2890	protein-(glutamine-N5) methyltransferase activity
Athai_35110	COG1490	D-aminoacyl-tRNA deacylase activity
Athai_35160	COG0123	including yeast histone deacetylase and acetoin utilization protein
Athai_35190	COG2267	carboxylic ester hydrolase activity
Athai_35230	COG1250	3-hydroxyacyl-CoA dehydrogenase
Athai_35240	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_35290	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Athai_35490	COG1674	ftsk spoiiie
Athai_35560	COG1250	3-hydroxyacyl-CoA dehydrogenase
Athai_35640	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Athai_35650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Athai_35660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Athai_35670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Athai_35680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Athai_35690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Athai_35700	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Athai_35710	COG0356	it plays a direct role in the translocation of protons across the membrane
Athai_35760	COG2890	protein-(glutamine-N5) methyltransferase activity
Athai_35780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Athai_35790	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Athai_35800	COG0254	rRNA binding
Athai_35850	COG1063	alcohol dehydrogenase
Athai_35860	COG2814	Major facilitator Superfamily
Athai_35890	COG0083	homoserine kinase activity
Athai_35920	COG2205	protein histidine kinase activity
Athai_35930	COG0745	RESPONSE REGULATOR receiver
Athai_35940	COG1136	(ABC) transporter
Athai_35990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Athai_36000	COG0460	homoserine dehydrogenase
Athai_36010	COG0019	diaminopimelate decarboxylase activity
Athai_36020	COG0018	arginyl-trna synthetase
Athai_36080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Athai_36110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Athai_36150	COG0842	Transport permease protein
Athai_36160	COG1131	(ABC) transporter
Athai_36170	COG1737	Transcriptional regulator
Athai_36180	COG3876	Protein conserved in bacteria
Athai_36190	COG3189	MarR family transcriptional regulator
Athai_36230	COG1230	cation diffusion facilitator family transporter
Athai_36240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Athai_36280	COG1741	Belongs to the pirin family
Athai_36290	COG0776	regulation of translation
Athai_36300	COG0667	Aldo Keto reductase
Athai_36360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Athai_36460	COG3469	chitinase activity
Athai_36470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Athai_36510	COG2321	neutral zinc metallopeptidase
Athai_36520	COG0247	lactate metabolic process
Athai_36530	COG0277	FAD linked oxidase domain protein
Athai_36550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Athai_36600	COG0442	prolyl-tRNA aminoacylation
Athai_36620	COG0174	glutamine synthetase
Athai_36640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Athai_36650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Athai_36650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Athai_36660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Athai_36680	COG0596	Alpha beta hydrolase
Athai_36730	COG1414	Transcriptional regulator
Athai_36740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Athai_36760	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_36780	COG2314	TM2 domain
Athai_36800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Athai_36850	COG0546	phosphoglycolate phosphatase activity
Athai_36950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Athai_36990	COG1024	Enoyl-CoA hydratase
Athai_37000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Athai_37010	COG2271	Major facilitator Superfamily
Athai_37020	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_37040	COG1609	Transcriptional regulator
Athai_37090	COG1620	l-lactate permease
Athai_37100	COG1573	uracil-dna glycosylase
Athai_37130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Athai_37150	COG0542	response to heat
Athai_37180	COG1063	alcohol dehydrogenase
Athai_37210	COG0740	serine-type endopeptidase activity
Athai_37280	COG0586	Pfam SNARE associated Golgi protein
Athai_37290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Athai_37300	COG0726	polysaccharide deacetylase
Athai_37320	COG3119	arylsulfatase activity
Athai_37360	COG1609	Transcriptional regulator
Athai_37370	COG0508	dehydrogenase complex catalyzes the overall conversion of
Athai_37380	COG0667	Aldo Keto reductase
Athai_37400	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Athai_37410	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Athai_37430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Athai_37460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Athai_37470	COG0508	dehydrogenase complex catalyzes the overall conversion of
Athai_37480	COG0384	phenazine biosynthesis protein PhzF
Athai_37560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Athai_37570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Athai_37600	COG1134	teichoic acid transport
Athai_37620	COG0321	lipoyl(octanoyl) transferase activity
Athai_37630	COG0017	Asparaginyl-tRNA synthetase
Athai_37650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Athai_37680	COG1846	Transcriptional regulator
Athai_37690	COG0697	spore germination
Athai_37700	COG2910	NAD(P)H-binding
Athai_37770	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_37780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Athai_37780	COG0512	Glutamine amidotransferase of anthranilate synthase
Athai_37790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Athai_37810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Athai_37840	COG4122	O-methyltransferase activity
Athai_37910	COG3119	arylsulfatase activity
Athai_37930	COG0395	ABC-type sugar transport system, permease component
Athai_37940	COG1175	transmembrane transport
Athai_38040	COG1175	transmembrane transport
Athai_38050	COG0395	ABC-type sugar transport system, permease component
Athai_38080	COG1846	Transcriptional regulator
Athai_38160	COG2837	iron assimilation
Athai_38200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Athai_38200	COG2755	lipolytic protein G-D-S-L family
Athai_38220	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Athai_38240	COG3835	regulator
Athai_38250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Athai_38260	COG1228	amidohydrolase
Athai_38290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Athai_38380	COG3119	arylsulfatase activity
Athai_38400	COG0395	ABC-type sugar transport system, permease component
Athai_38410	COG4209	transmembrane transport
Athai_38430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Athai_38440	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Athai_38470	COG1595	DNA-templated transcription, initiation
Athai_38580	COG3153	acetyltransferase
Athai_38680	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
Athai_38710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Athai_38810	COG0666	response to abiotic stimulus
Athai_38950	COG1121	(ABC) transporter
Athai_39020	COG0395	ABC-type sugar transport system, permease component
Athai_39060	COG1920	GTP binding
Athai_39090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Athai_39130	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_39150	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_39160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Athai_39180	COG1414	Transcriptional regulator
Athai_39250	COG2226	methyltransferase
Athai_39370	COG0714	Associated with various cellular activities
Athai_39410	COG1733	regulation of RNA biosynthetic process
Athai_39450	COG0671	phosphoesterase, PA-phosphatase related
Athai_39500	COG0018	arginyl-trna synthetase
Athai_39550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Athai_39560	COG3938	Belongs to the proline racemase family
Athai_39590	COG1595	DNA-templated transcription, initiation
Athai_39610	COG2205	protein histidine kinase activity
Athai_39620	COG0745	RESPONSE REGULATOR receiver
Athai_39680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Athai_39690	COG1086	Polysaccharide biosynthesis protein
Athai_39700	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Athai_39720	COG2089	acid synthase
Athai_39760	COG0318	PFAM AMP-dependent synthetase and ligase
Athai_39770	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_39820	COG0667	Aldo Keto reductase
Athai_39940	COG1131	(ABC) transporter
Athai_39970	COG0358	DNA primase activity
Athai_39980	COG1846	Transcriptional regulator
Athai_39990	COG1132	(ABC) transporter
Athai_40060	COG0277	FAD linked oxidase domain protein
Athai_40060	COG0247	lactate metabolic process
Athai_40070	COG1690	Belongs to the RtcB family
Athai_40110	COG0477	Major facilitator Superfamily
Athai_40130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Athai_40210	COG0574	Belongs to the PEP-utilizing enzyme family
Athai_40210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Athai_40290	COG0423	glycine-tRNA ligase activity
Athai_40400	COG4721	ABC-type cobalt transport system, permease component
Athai_40410	COG1122	ATPase activity
Athai_40430	COG0246	Mannitol dehydrogenase
Athai_40440	COG0246	Mannitol dehydrogenase
Athai_40450	COG1937	Protein conserved in bacteria
Athai_40470	COG3959	Transketolase, thiamine diphosphate binding domain
Athai_40480	COG4632	Exopolysaccharide biosynthesis protein
Athai_40480	COG5434	Belongs to the glycosyl hydrolase 28 family
Athai_40500	COG0137	argininosuccinate synthase activity
Athai_40670	COG0714	Associated with various cellular activities
Athai_40680	COG3552	Protein containing von Willebrand factor type A (VWA) domain
Athai_40720	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_40730	COG1309	transcriptional regulator
Athai_40770	COG1960	acyl-CoA dehydrogenase activity
Athai_40790	COG1309	transcriptional regulator
Athai_40810	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_40820	COG0183	Belongs to the thiolase family
Athai_40870	COG2072	flavoprotein involved in K transport
Athai_40890	COG4221	oxidoreductase activity
Athai_40920	COG1643	Atp-dependent helicase
Athai_40950	COG2358	TRAP transporter, solute receptor (TAXI family
Athai_40960	COG5002	protein histidine kinase activity
Athai_40970	COG0745	RESPONSE REGULATOR receiver
Athai_40990	COG0737	Belongs to the 5'-nucleotidase family
Athai_41000	COG0166	Belongs to the GPI family
Athai_41030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Athai_41040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Athai_41060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Athai_41080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Athai_41120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Athai_41160	COG0252	asparaginase activity
Athai_41170	COG3537	Alpha-1,2-mannosidase
Athai_41180	COG3537	Alpha-1,2-mannosidase
Athai_41190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Athai_41210	COG1196	nuclear chromosome segregation
Athai_41230	COG1609	Transcriptional regulator
Athai_41290	COG2226	methyltransferase
Athai_41300	COG0515	serine threonine protein kinase
Athai_41300	COG2815	serine threonine protein kinase
Athai_41310	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Athai_41320	COG1733	regulation of RNA biosynthetic process
Athai_41340	COG0667	Aldo Keto reductase
Athai_41350	COG0667	Aldo Keto reductase
Athai_41400	COG3511	phospholipase C
Athai_41420	COG3511	phospholipase C
Athai_41430	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Athai_41440	COG2814	Major facilitator Superfamily
Athai_41450	COG1309	transcriptional regulator
Athai_41540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Athai_41620	COG2072	flavoprotein involved in K transport
Athai_41690	COG0028	Belongs to the TPP enzyme family
Athai_41700	COG1063	alcohol dehydrogenase
Athai_41710	COG0156	8-amino-7-oxononanoate synthase activity
Athai_41760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Athai_41770	COG0583	DNA-binding transcription factor activity
Athai_41800	COG1940	carbohydrate kinase activity
Athai_41900	COG0438	transferase activity, transferring glycosyl groups
Athai_41910	COG2755	lipolytic protein G-D-S-L family
Athai_41910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Athai_41920	COG0501	Belongs to the peptidase M48B family
Athai_41930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Athai_41970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Athai_41990	COG2124	cytochrome p450
Athai_42010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Athai_42020	COG1595	DNA-templated transcription, initiation
Athai_42040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Athai_42150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Athai_42200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Athai_42210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Athai_42240	COG1929	Belongs to the glycerate kinase type-1 family
Athai_42260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Athai_42270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Athai_42350	COG4608	Belongs to the ABC transporter superfamily
Athai_42360	COG0444	Belongs to the ABC transporter superfamily
Athai_42370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_42380	COG0601	transmembrane transport
Athai_42390	COG4166	transmembrane transport
Athai_42400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Athai_42450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Athai_42460	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Athai_42470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Athai_42480	COG1530	ribonuclease E activity
Athai_42510	COG1051	belongs to the nudix hydrolase family
Athai_42570	COG1136	(ABC) transporter
Athai_42640	COG1595	DNA-templated transcription, initiation
Athai_42650	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Athai_42680	COG1733	regulation of RNA biosynthetic process
Athai_42700	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Athai_42720	COG0154	amidase activity
Athai_42780	COG0668	transmembrane transport
Athai_42810	COG0366	Alpha amylase catalytic
Athai_42830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Athai_42890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Athai_42900	COG4585	Histidine kinase
Athai_42910	COG2197	response regulator
Athai_42920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Athai_42950	COG2337	Toxic component of a toxin-antitoxin (TA) module
Athai_42970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Athai_43010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Athai_43020	COG1940	carbohydrate kinase activity
Athai_43050	COG0395	ABC-type sugar transport system, permease component
Athai_43060	COG1175	transmembrane transport
Athai_43070	COG2182	Extracellular solute-binding protein
Athai_43080	COG1609	Transcriptional regulator
Athai_43090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Athai_43100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Athai_43110	COG1366	Belongs to the anti-sigma-factor antagonist family
Athai_43190	COG0513	Belongs to the DEAD box helicase family
Athai_43300	COG2095	MarC family integral membrane protein
Athai_43310	COG0613	PHP domain protein
Athai_43450	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_43490	COG2239	Acts as a magnesium transporter
Athai_43560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Athai_43570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Athai_43710	COG0737	Belongs to the 5'-nucleotidase family
Athai_43740	COG0300	oxidoreductase activity
Athai_43750	COG0697	spore germination
Athai_43770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Athai_43780	COG1396	sequence-specific DNA binding
Athai_43790	COG0740	serine-type endopeptidase activity
Athai_43800	COG0740	serine-type endopeptidase activity
Athai_43810	COG1335	isochorismatase
Athai_43820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Athai_43850	COG1597	lipid kinase activity
Athai_43880	COG0175	sulfate reduction
Athai_43910	COG1672	PFAM Archaeal ATPase
Athai_43910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Athai_43950	COG0667	Aldo Keto reductase
Athai_44010	COG3384	dioxygenase
Athai_44040	COG1174	glycine betaine transport
Athai_44060	COG1174	glycine betaine transport
Athai_44080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Athai_44090	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Athai_44110	COG5662	AntiSigma factor
Athai_44120	COG1595	DNA-templated transcription, initiation
Athai_44150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Athai_44200	COG0483	inositol monophosphate 1-phosphatase activity
Athai_44340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Athai_44380	COG0395	ABC-type sugar transport system, permease component
Athai_44390	COG1175	transmembrane transport
Athai_44410	COG1940	carbohydrate kinase activity
Athai_44490	COG1940	carbohydrate kinase activity
Athai_44490	COG1846	Transcriptional regulator
Athai_44520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Athai_44530	COG1940	carbohydrate kinase activity
Athai_44530	COG1846	Transcriptional regulator
Athai_44550	COG3387	PFAM Glycoside hydrolase 15-related
Athai_44670	COG1846	Transcriptional regulator
Athai_44690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Athai_44830	COG0612	Peptidase, M16
Athai_45040	COG2211	Major facilitator Superfamily
Athai_45100	COG1309	transcriptional regulator
Athai_45110	COG1064	alcohol dehydrogenase
Athai_45150	COG3119	arylsulfatase activity
Athai_45180	COG1309	transcriptional regulator
Athai_45200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Athai_45250	COG0601	transmembrane transport
Athai_45270	COG4608	Belongs to the ABC transporter superfamily
Athai_45290	COG2195	Cleaves the N-terminal amino acid of tripeptides
Athai_45310	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_45390	COG1228	amidohydrolase
Athai_45500	COG2304	oxidoreductase activity
Athai_45510	COG1802	Transcriptional regulator
Athai_45520	COG0477	Major facilitator Superfamily
Athai_45540	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_45560	COG0477	Major facilitator Superfamily
Athai_45580	COG2814	Major facilitator Superfamily
Athai_45670	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_45690	COG0583	DNA-binding transcription factor activity
Athai_45760	COG1674	ftsk spoiiie
Athai_45830	COG3903	Transcriptional regulator
Athai_45830	COG3629	intracellular signal transduction
Athai_45840	COG1335	isochorismatase
Athai_45870	COG0656	L-ascorbic acid biosynthetic process
Athai_45920	COG0583	DNA-binding transcription factor activity
Athai_45940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Athai_46010	COG1733	regulation of RNA biosynthetic process
Athai_46130	COG0667	Aldo Keto reductase
Athai_46150	COG1802	Transcriptional regulator
Athai_46210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Athai_46220	COG0402	S-adenosylhomocysteine deaminase activity
Athai_46230	COG2814	Major facilitator Superfamily
Athai_46250	COG2318	DinB family
Athai_46300	COG2197	response regulator
Athai_46310	COG4585	Histidine kinase
Athai_46320	COG0577	efflux transmembrane transporter activity
Athai_46320	COG1136	(ABC) transporter
Athai_46360	COG3537	Alpha-1,2-mannosidase
Athai_46390	COG0739	heme binding
Athai_46400	COG4221	oxidoreductase activity
Athai_46460	COG4942	peptidase
Athai_46530	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Athai_46550	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Athai_46640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Athai_46660	COG1201	RNA secondary structure unwinding
Athai_46710	COG0758	DNA mediated transformation
Athai_46750	COG3293	Transposase
Athai_46890	COG4257	antibiotic catabolic process
Athai_46920	COG2197	response regulator
Athai_46930	COG4585	Histidine kinase
Athai_46950	COG0668	transmembrane transport
Athai_47230	COG2197	response regulator
Athai_47310	COG0542	response to heat
Athai_47340	COG3119	arylsulfatase activity
Athai_47370	COG0395	ABC-type sugar transport system, permease component
Athai_47380	COG1175	transmembrane transport
Athai_47400	COG1940	carbohydrate kinase activity
Athai_47410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Athai_47420	COG4279	zinc finger
Athai_47460	COG4821	SIS domain
Athai_47490	COG0330	HflC and HflK could
Athai_47500	COG3158	transport of potassium into the cell
Athai_47560	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_47590	COG0583	DNA-binding transcription factor activity
Athai_47620	COG0789	Transcriptional regulator
Athai_47630	COG0659	secondary active sulfate transmembrane transporter activity
Athai_47650	COG1595	DNA-templated transcription, initiation
Athai_47720	COG0357	Ribosomal RNA small subunit methyltransferase G
Athai_47730	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_47760	COG2409	Drug exporters of the RND superfamily
Athai_47780	COG1234	tRNA 3'-trailer cleavage
Athai_47790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Athai_47800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Athai_47900	COG2022	thiamine diphosphate biosynthetic process
Athai_47900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Athai_48000	COG0596	Alpha beta hydrolase
Athai_48030	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_48040	COG2267	carboxylic ester hydrolase activity
Athai_48190	COG2197	response regulator
Athai_48200	COG4585	Histidine kinase
Athai_48250	COG2197	response regulator
Athai_48300	COG1132	(ABC) transporter
Athai_48350	COG0604	alcohol dehydrogenase
Athai_48350	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_48350	COG3321	synthase
Athai_48430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Athai_48460	COG1595	DNA-templated transcription, initiation
Athai_48500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Athai_48530	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_48650	COG2226	methyltransferase
Athai_48770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Athai_48780	COG3251	PFAM MbtH domain protein
Athai_48800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Athai_48810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Athai_48840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Athai_48940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Athai_49040	COG3795	YCII-related domain
Athai_49050	COG4941	Belongs to the sigma-70 factor family
Athai_49060	COG2318	DinB family
Athai_49070	COG2197	response regulator
Athai_49080	COG4585	Histidine kinase
Athai_49120	COG3973	AAA domain
Athai_49130	COG0443	Heat shock 70 kDa protein
Athai_49190	COG1595	DNA-templated transcription, initiation
Athai_49200	COG1595	DNA-templated transcription, initiation
Athai_49260	COG0586	Pfam SNARE associated Golgi protein
Athai_49270	COG4585	Histidine kinase
Athai_49280	COG2197	response regulator
Athai_49410	COG1482	cell wall glycoprotein biosynthetic process
Athai_49440	COG2835	tetraacyldisaccharide 4'-kinase activity
Athai_49450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Athai_49510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Athai_49560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Athai_49580	COG0438	transferase activity, transferring glycosyl groups
Athai_49630	COG2267	carboxylic ester hydrolase activity
Athai_49640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Athai_49660	COG2188	Transcriptional regulator
Athai_49700	COG1607	acyl-coa hydrolase
Athai_49720	COG2267	carboxylic ester hydrolase activity
Athai_49750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Athai_49800	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Athai_49810	COG1832	CoA-binding protein
Athai_49830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Athai_49950	COG1302	Protein conserved in bacteria
Athai_49980	COG3848	Pyruvate phosphate dikinase
Athai_49980	COG0574	Belongs to the PEP-utilizing enzyme family
Athai_49990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Athai_50070	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Athai_50100	COG0424	maF-like protein
Athai_50120	COG3345	alpha-galactosidase
Athai_50140	COG1742	UPF0060 membrane protein
Athai_50280	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_50470	COG1175	transmembrane transport
Athai_50490	COG1653	transport
Athai_50520	COG2226	methyltransferase
Athai_50560	COG2197	response regulator
Athai_50570	COG4585	Histidine kinase
Athai_50600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Athai_50620	COG0488	(ABC) transporter
Athai_50690	COG1131	(ABC) transporter
Athai_50710	COG2226	methyltransferase
Athai_50780	COG0546	phosphoglycolate phosphatase activity
Athai_50790	COG2188	Transcriptional regulator
Athai_50940	COG1615	UPF0182 protein
Athai_50950	COG3480	Lon protease (S16) C-terminal proteolytic domain
Athai_50990	COG1309	transcriptional regulator
Athai_51020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Athai_51040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Athai_51100	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Athai_51110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Athai_51120	COG1562	ergosterol biosynthetic process
Athai_51140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Athai_51160	COG1657	PFAM Prenyltransferase squalene oxidase
Athai_51240	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Athai_51250	COG3537	Alpha-1,2-mannosidase
Athai_51260	COG0297	glycogen (starch) synthase activity
Athai_51310	COG2197	response regulator
Athai_51320	COG3851	Histidine kinase
Athai_51340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Athai_51350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Athai_51380	COG1024	Enoyl-CoA hydratase
Athai_51400	COG0519	Catalyzes the synthesis of GMP from XMP
Athai_51420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Athai_51450	COG1611	Belongs to the LOG family
Athai_51460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Athai_51480	COG4946	Tricorn protease homolog
Athai_51480	COG1506	peptidase
Athai_51480	COG0823	Involved in the tonB-independent uptake of proteins
Athai_51490	COG2171	N-acyltransferase activity
Athai_51560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Athai_51650	COG4166	transmembrane transport
Athai_51670	COG4166	transmembrane transport
Athai_51700	COG2018	Roadblock/LC7 domain
Athai_51830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Athai_51850	COG0662	Cupin 2, conserved barrel domain protein
Athai_51850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Athai_51860	COG0542	response to heat
Athai_51890	COG1079	Belongs to the binding-protein-dependent transport system permease family
Athai_51900	COG4603	Belongs to the binding-protein-dependent transport system permease family
Athai_51910	COG3845	ABC transporter
Athai_51920	COG1744	ABC transporter substrate-binding protein PnrA-like
Athai_51950	COG1309	transcriptional regulator
Athai_51970	COG0180	Tryptophanyl-tRNA synthetase
Athai_51980	COG0395	ABC-type sugar transport system, permease component
Athai_51990	COG1175	transmembrane transport
Athai_52010	COG1349	DNA-binding transcription factor activity
Athai_52030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Athai_52040	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Athai_52090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Athai_52130	COG0477	Major facilitator Superfamily
Athai_52140	COG3311	Transcriptional regulator
Athai_52180	COG0395	ABC-type sugar transport system, permease component
Athai_52310	COG0789	Transcriptional regulator
Athai_52330	COG0138	bifunctional purine biosynthesis protein purh
Athai_52410	COG0045	succinate-CoA ligase (ADP-forming) activity
Athai_52450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Athai_52470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Athai_52550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Athai_52580	COG2197	response regulator
Athai_52590	COG4585	Histidine kinase
Athai_52630	COG0688	phosphatidylethanolamine metabolic process
Athai_52670	COG2197	response regulator
Athai_52680	COG1183	phosphatidylcholine synthase activity
Athai_52690	COG1056	cytidyltransferase-related domain
Athai_52690	COG1051	belongs to the nudix hydrolase family
Athai_52710	COG0519	Catalyzes the synthesis of GMP from XMP
Athai_52710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Athai_52770	COG4211	Belongs to the binding-protein-dependent transport system permease family
Athai_52780	COG0657	acetylesterase activity
Athai_52830	COG0395	ABC-type sugar transport system, permease component
Athai_52850	COG1175	transmembrane transport
Athai_52930	COG0531	amino acid
Athai_52970	COG0516	GMP reductase activity
Athai_53020	COG2197	response regulator
Athai_53050	COG0459	protein refolding
Athai_53060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Athai_53090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Athai_53100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Athai_53110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Athai_53130	COG1132	(ABC) transporter
Athai_53170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Athai_53180	COG0456	acetyltransferase
Athai_53190	COG0456	acetyltransferase
Athai_53190	COG1214	PFAM Peptidase M22, glycoprotease
Athai_53210	COG0802	atpase or kinase
Athai_53230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Athai_53260	COG1505	serine-type exopeptidase activity
Athai_53280	COG0667	Aldo Keto reductase
Athai_53290	COG0583	DNA-binding transcription factor activity
Athai_53320	COG4977	sequence-specific DNA binding
Athai_53340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Athai_53370	COG0583	DNA-binding transcription factor activity
Athai_53380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Athai_53390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Athai_53400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Athai_53420	COG2814	Major facilitator Superfamily
Athai_53450	COG0488	(ABC) transporter
Athai_53460	COG2813	Specifically methylates the guanine in position
Athai_53510	COG0583	DNA-binding transcription factor activity
Athai_53550	COG0101	tRNA pseudouridine synthase activity
Athai_53560	COG0203	ribosomal protein L17
Athai_53570	COG0202	RNA polymerase activity
Athai_53580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Athai_53590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Athai_53600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Athai_53610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Athai_53640	COG0563	adenylate kinase activity
Athai_53660	COG0200	Binds to the 23S rRNA
Athai_53670	COG1841	ribosomal large subunit assembly
Athai_53680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Athai_53690	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Athai_53700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Athai_53710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Athai_53720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Athai_53730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Athai_53740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Athai_53750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Athai_53760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Athai_53770	COG0255	Belongs to the universal ribosomal protein uL29 family
Athai_53780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Athai_53790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Athai_53800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Athai_53810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Athai_53820	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Athai_53830	COG0089	rRNA binding
Athai_53840	COG0088	Forms part of the polypeptide exit tunnel
Athai_53850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Athai_53860	COG0051	transcription antitermination factor activity, RNA binding
Athai_53870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Athai_53880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Athai_53890	COG0049	tRNA binding
Athai_53900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Athai_53930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Athai_53940	COG0085	RNA polymerase activity
Athai_53980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Athai_54030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Athai_54040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Athai_54060	COG0222	ribosome binding
Athai_54080	COG0081	regulation of translation
Athai_54090	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Athai_54110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Athai_54130	COG2030	dehydratase
Athai_54140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Athai_54150	COG5001	Diguanylate cyclase
Athai_54150	COG3300	MHYT domain
Athai_54170	COG1733	regulation of RNA biosynthetic process
Athai_54210	COG0640	Transcriptional regulator
Athai_54280	COG2226	methyltransferase
Athai_54520	COG1666	GTP binding
Athai_54530	COG2315	Protein conserved in bacteria
Athai_54540	COG2267	carboxylic ester hydrolase activity
Athai_54560	COG0501	Belongs to the peptidase M48B family
Athai_54570	COG1007	ATP synthesis coupled electron transport
Athai_54590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Athai_54600	COG0713	ATP synthesis coupled electron transport
Athai_54610	COG0839	Belongs to the complex I subunit 6 family
Athai_54630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Athai_54640	COG0667	Aldo Keto reductase
Athai_54690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Athai_54700	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Athai_54710	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Athai_54740	COG0674	pyruvate-flavodoxin oxidoreductase activity
Athai_54740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Athai_54750	COG1013	pyruvate-flavodoxin oxidoreductase activity
Athai_54790	COG1950	PFAM Membrane protein of
Athai_54880	COG1404	Belongs to the peptidase S8 family
Athai_54890	COG1309	transcriptional regulator
Athai_54940	COG2267	carboxylic ester hydrolase activity
Athai_54970	COG0142	geranyltranstransferase activity
Athai_54980	COG1007	ATP synthesis coupled electron transport
Athai_55010	COG0713	ATP synthesis coupled electron transport
Athai_55030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Athai_55040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Athai_55050	COG1034	ATP synthesis coupled electron transport
Athai_55060	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Athai_55080	COG0649	NAD binding
Athai_55090	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Athai_55100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Athai_55130	COG2226	methyltransferase
Athai_55180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Athai_55190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Athai_55260	COG3396	Phenylacetate-CoA oxygenase
Athai_55270	COG0644	oxidoreductase
Athai_55310	COG2050	protein possibly involved in aromatic compounds catabolism
Athai_55330	COG1022	Amp-dependent synthetase and ligase
Athai_55350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Athai_55360	COG2151	metal-sulfur cluster biosynthetic enzyme
Athai_55370	COG3396	Phenylacetate-CoA oxygenase
Athai_55380	COG3460	Phenylacetate-CoA oxygenase
Athai_55390	COG3396	Phenylacetate-CoA oxygenase
Athai_55410	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Athai_55440	COG1051	belongs to the nudix hydrolase family
Athai_55460	COG3973	AAA domain
Athai_55470	COG1252	NADH dehydrogenase
Athai_55490	COG1120	ATPase activity
Athai_55500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Athai_55520	COG1802	Transcriptional regulator
Athai_55550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_55560	COG0444	Belongs to the ABC transporter superfamily
Athai_55570	COG4608	Belongs to the ABC transporter superfamily
Athai_55580	COG0405	Gamma-glutamyltransferase
Athai_55590	COG2755	lipolytic protein G-D-S-L family
Athai_55590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Athai_55740	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Athai_55790	COG0542	response to heat
Athai_55810	COG1803	Methylglyoxal synthase
Athai_55830	COG3654	unkown
Athai_55840	COG1522	sequence-specific DNA binding
Athai_55850	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Athai_55870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Athai_55900	COG4290	ribonuclease
Athai_55970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Athai_55980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Athai_56030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Athai_56070	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Athai_56080	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Athai_56130	COG1194	a g-specific adenine glycosylase
Athai_56160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Athai_56170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Athai_56220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Athai_56240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Athai_56250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Athai_56260	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Athai_56300	COG4585	Histidine kinase
Athai_56360	COG1175	transmembrane transport
Athai_56390	COG1082	Xylose isomerase domain protein TIM barrel
Athai_56420	COG0745	RESPONSE REGULATOR receiver
Athai_56430	COG5002	protein histidine kinase activity
Athai_56490	COG0588	phosphoglycerate mutase activity
Athai_56530	COG0438	transferase activity, transferring glycosyl groups
Athai_56570	COG3896	Chloramphenicol phosphotransferase-like protein
Athai_56640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Athai_56660	COG0785	Cytochrome C biogenesis protein
Athai_56670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Athai_56680	COG0406	alpha-ribazole phosphatase activity
Athai_56690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Athai_56740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Athai_56750	COG4941	Belongs to the sigma-70 factor family
Athai_56790	COG3469	chitinase activity
Athai_56820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Athai_56830	COG0765	amino acid transport
Athai_56840	COG1126	abc transporter atp-binding protein
Athai_56900	COG0113	porphobilinogen synthase activity
Athai_56910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Athai_56910	COG1648	precorrin-2 dehydrogenase activity
Athai_56920	COG0181	hydroxymethylbilane synthase activity
Athai_56930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Athai_56940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Athai_56960	COG2197	response regulator
Athai_56970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Athai_56980	COG2267	carboxylic ester hydrolase activity
Athai_57170	COG1674	ftsk spoiiie
Athai_57250	COG1404	Belongs to the peptidase S8 family
Athai_57310	COG2205	protein histidine kinase activity
Athai_57310	COG0784	Response regulator, receiver
Athai_57330	COG1404	Belongs to the peptidase S8 family
Athai_57350	COG0702	epimerase
Athai_57360	COG0277	FAD linked oxidase domain protein
Athai_57370	COG0277	FAD linked oxidase domain protein
Athai_57380	COG0247	lactate metabolic process
Athai_57410	COG0640	Transcriptional regulator
Athai_57440	COG2188	Transcriptional regulator
Athai_57450	COG4585	Histidine kinase
Athai_57460	COG2378	regulation of single-species biofilm formation
Athai_57490	COG2378	regulation of single-species biofilm formation
Athai_57500	COG1968	undecaprenyl-diphosphatase activity
Athai_57510	COG2258	MOSC domain
Athai_57550	COG3145	DNA-N1-methyladenine dioxygenase activity
Athai_57580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Athai_57600	COG2197	response regulator
Athai_57610	COG2205	protein histidine kinase activity
Athai_57620	COG0745	RESPONSE REGULATOR receiver
Athai_57640	COG1716	ATPase activity
Athai_57710	COG1674	ftsk spoiiie
Athai_57750	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_57760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Athai_57800	COG1595	DNA-templated transcription, initiation
Athai_57880	COG0183	Belongs to the thiolase family
Athai_57900	COG0583	DNA-binding transcription factor activity
Athai_58120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Athai_58140	COG0003	Pfam Anion-transporting ATPase
Athai_58290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Athai_58380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Athai_58400	COG0583	DNA-binding transcription factor activity
Athai_58410	COG0640	Transcriptional regulator
Athai_58430	COG0477	Major facilitator Superfamily
Athai_58440	COG1309	transcriptional regulator
Athai_58450	COG2197	response regulator
Athai_58460	COG4585	Histidine kinase
Athai_58470	COG1131	(ABC) transporter
Athai_58710	COG0776	regulation of translation
Athai_58720	COG0443	Heat shock 70 kDa protein
Athai_58730	COG0477	Major facilitator Superfamily
Athai_58810	COG0583	DNA-binding transcription factor activity
Athai_58820	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Athai_58850	COG1733	regulation of RNA biosynthetic process
Athai_58880	COG0693	protein deglycase activity
Athai_58890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Athai_58950	COG0789	Transcriptional regulator
Athai_58970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Athai_59010	COG0789	Transcriptional regulator
Athai_59090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Athai_59170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Athai_59190	COG0813	purine-nucleoside phosphorylase activity
Athai_59210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Athai_59270	COG0287	Prephenate dehydrogenase
Athai_59280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Athai_59280	COG0235	Class ii aldolase
Athai_59290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Athai_59290	COG1796	DNA polymerase
Athai_59320	COG2936	dipeptidyl-peptidase activity
Athai_59330	COG1902	pentaerythritol trinitrate reductase activity
Athai_59360	COG0477	Major facilitator Superfamily
Athai_59390	COG0395	ABC-type sugar transport system, permease component
Athai_59400	COG1175	transmembrane transport
Athai_59420	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_59430	COG2186	Transcriptional regulator
Athai_59440	COG4948	Mandelate Racemase Muconate Lactonizing
Athai_59460	COG1126	abc transporter atp-binding protein
Athai_59470	COG0765	amino acid transport
Athai_59480	COG0765	amino acid transport
Athai_59490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Athai_59530	COG0456	acetyltransferase
Athai_59550	COG4608	Belongs to the ABC transporter superfamily
Athai_59560	COG0444	Belongs to the ABC transporter superfamily
Athai_59570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Athai_59580	COG0601	transmembrane transport
Athai_59590	COG1414	Transcriptional regulator
Athai_59600	COG0406	alpha-ribazole phosphatase activity
Athai_59650	COG1609	Transcriptional regulator
Athai_59680	COG0800	Aldolase
Athai_59700	COG1414	Transcriptional regulator
Athai_59710	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Athai_59740	COG4585	Histidine kinase
Athai_59750	COG2197	response regulator
Athai_59810	COG1120	ATPase activity
Athai_59840	COG0477	Major facilitator Superfamily
Athai_59850	COG1473	amidohydrolase
Athai_59930	COG2318	DinB family
Athai_60060	COG1940	carbohydrate kinase activity
Athai_60150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Athai_60190	COG2814	Major facilitator Superfamily
Athai_60250	COG0110	maltose O-acetyltransferase activity
Athai_60260	COG1136	(ABC) transporter
Athai_60300	COG2197	response regulator
Athai_60340	COG4941	Belongs to the sigma-70 factor family
Athai_60360	COG0477	Major facilitator Superfamily
Athai_60410	COG1376	ErfK ybiS ycfS ynhG family protein
Athai_60550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Athai_60560	COG0798	PFAM Bile acid sodium symporter
Athai_60580	COG0640	Transcriptional regulator
Athai_60640	COG0640	Transcriptional regulator
Athai_60700	COG2208	phosphoserine phosphatase activity
Athai_60730	COG2814	Major facilitator Superfamily
Athai_60750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Athai_60770	COG3226	Transcriptional regulator
Athai_60830	COG1522	sequence-specific DNA binding
Athai_60930	COG1252	NADH dehydrogenase
Athai_60950	COG1595	DNA-templated transcription, initiation
Athai_61010	COG2197	response regulator
Athai_61020	COG3851	Histidine kinase
Athai_61030	COG3963	phosphatidate phosphatase activity
Athai_61070	COG2201	protein-glutamate methylesterase activity
Athai_61080	COG2197	response regulator
Athai_61090	COG4585	Histidine kinase
Athai_61180	COG0656	L-ascorbic acid biosynthetic process
Athai_61210	COG1073	alpha beta
Athai_61260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Athai_61310	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_61320	COG1609	Transcriptional regulator
Athai_61360	COG0702	epimerase
Athai_61390	COG3458	cephalosporin-C deacetylase activity
Athai_61430	COG0395	ABC-type sugar transport system, permease component
Athai_61440	COG1175	transmembrane transport
Athai_61490	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Athai_61500	COG1691	(AIR) carboxylase
Athai_61540	COG4106	trans-aconitate 2-methyltransferase activity
Athai_61580	COG1414	Transcriptional regulator
Athai_61600	COG0406	alpha-ribazole phosphatase activity
Athai_61610	COG0500	methyltransferase
Athai_61620	COG2205	protein histidine kinase activity
Athai_61630	COG0745	RESPONSE REGULATOR receiver
Athai_61680	COG1764	response to oxidative stress
Athai_61690	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Athai_61700	COG0561	phosphatase activity
Athai_61720	COG0443	Heat shock 70 kDa protein
Athai_61730	COG0561	phosphatase activity
Athai_61780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Athai_61810	COG3958	Transketolase
Athai_61820	COG3959	Transketolase, thiamine diphosphate binding domain
Athai_61830	COG0789	Transcriptional regulator
Athai_61840	COG2084	Dehydrogenase
Athai_61850	COG4585	Histidine kinase
Athai_61940	COG2197	response regulator
Athai_61950	COG4585	Histidine kinase
Athai_61970	COG1733	regulation of RNA biosynthetic process
Athai_61990	COG0205	6-phosphofructokinase activity
Athai_62020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Athai_62050	COG1021	2,3-dihydroxybenzoate-AMP ligase
Athai_62070	COG0584	glycerophosphoryl diester phosphodiesterase
Athai_62090	COG0583	DNA-binding transcription factor activity
Athai_62100	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Athai_62130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Athai_62140	COG0501	Belongs to the peptidase M48B family
Athai_62170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Athai_62200	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Athai_62260	COG1234	tRNA 3'-trailer cleavage
Athai_62290	COG4221	oxidoreductase activity
Athai_62400	COG2837	iron assimilation
Athai_62420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Athai_62460	COG5002	protein histidine kinase activity
Athai_62480	COG1316	TRANSCRIPTIONal
Athai_62490	COG1316	TRANSCRIPTIONal
Athai_62510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Athai_62530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Athai_62540	COG0438	transferase activity, transferring glycosyl groups
Athai_62550	COG2026	Addiction module toxin, RelE StbE family
Athai_62690	COG3293	Transposase
Athai_62770	COG0740	serine-type endopeptidase activity
Athai_62810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Athai_62820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Athai_62840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Athai_62860	COG1131	(ABC) transporter
Athai_62870	COG3559	Exporter of polyketide antibiotics
Athai_62880	COG0577	efflux transmembrane transporter activity
Athai_62890	COG1136	(ABC) transporter
Athai_62890	COG0577	efflux transmembrane transporter activity
Athai_62920	COG0745	RESPONSE REGULATOR receiver
Athai_62930	COG2205	protein histidine kinase activity
Athai_62940	COG1132	(ABC) transporter
Athai_62970	COG4221	oxidoreductase activity
Athai_62980	COG1309	transcriptional regulator
Athai_62990	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_63000	COG1716	ATPase activity
Athai_63000	COG1716	ATPase activity
Athai_63010	COG1716	ATPase activity
Athai_63040	COG0768	penicillin binding
Athai_63050	COG0515	serine threonine protein kinase
Athai_63060	COG0515	serine threonine protein kinase
Athai_63060	COG2815	serine threonine protein kinase
Athai_63130	COG0183	Belongs to the thiolase family
Athai_63180	COG0598	Magnesium transport protein CorA
Athai_63190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Athai_63220	COG2826	transposase and inactivated derivatives, IS30 family
Athai_63240	COG1881	PFAM PEBP family protein
Athai_63270	COG1960	acyl-CoA dehydrogenase activity
Athai_63280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Athai_63320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Athai_63340	COG0439	Biotin carboxylase
Athai_63350	COG3629	intracellular signal transduction
Athai_63350	COG3903	Transcriptional regulator
Athai_63470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Athai_63590	COG2318	DinB family
Athai_63600	COG3293	Transposase
Athai_63640	COG4974	Belongs to the 'phage' integrase family
Athai_63670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Athai_63690	COG1595	DNA-templated transcription, initiation
Athai_63710	COG1595	DNA-templated transcription, initiation
Athai_63730	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Athai_63740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Athai_63750	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Athai_63760	COG0592	DNA-directed DNA polymerase activity
Athai_63770	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Athai_63780	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Athai_63790	COG0594	ribonuclease P activity
Athai_63800	COG0706	membrane insertase activity
Athai_63830	COG0357	Ribosomal RNA small subunit methyltransferase G
Athai_63840	COG1192	Involved in chromosome partitioning
Athai_63860	COG1247	-acetyltransferase
Athai_63880	COG2382	esterase
Athai_63890	COG1181	Belongs to the D-alanine--D-alanine ligase family
Athai_63900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Athai_63920	COG0860	N-Acetylmuramoyl-L-alanine amidase
Athai_63920	COG3409	Peptidoglycan-binding domain 1 protein
Athai_63930	COG3118	belongs to the thioredoxin family
Athai_63960	COG1595	DNA-templated transcription, initiation
Athai_64020	COG0617	tRNA 3'-terminal CCA addition
Athai_64090	COG2132	Multicopper oxidase
Athai_64100	COG2268	Band 7 protein
Athai_64120	COG2027	D-alanyl-D-alanine carboxypeptidase
Athai_64130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Athai_64140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Athai_64190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Athai_64230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Athai_64260	COG0360	Binds together with S18 to 16S ribosomal RNA
Athai_64270	COG0629	single-stranded DNA binding
Athai_64280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Athai_64290	COG0359	binds to the 23S rRNA
Athai_64310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Athai_64340	COG1070	Carbohydrate kinase
Athai_64360	COG2304	oxidoreductase activity
Athai_64370	COG1796	DNA polymerase
Athai_64370	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Athai_64400	COG0667	Aldo Keto reductase
Athai_64430	COG0702	epimerase
Athai_64440	COG2186	Transcriptional regulator
Athai_64500	COG0315	cyclic pyranopterin monophosphate synthase activity
Athai_64510	COG0521	Mo-molybdopterin cofactor biosynthetic process
Athai_64540	COG1051	belongs to the nudix hydrolase family
Athai_64600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Athai_64630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Athai_64690	COG1216	Glycosyl transferase, family 2
Athai_64700	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Athai_64730	COG1960	acyl-CoA dehydrogenase activity
Athai_64770	COG1984	allophanate hydrolase subunit 2
Athai_64780	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Athai_64790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Athai_64840	COG0508	dehydrogenase complex catalyzes the overall conversion of
Athai_64850	COG0022	dehydrogenase e1 component
Athai_64950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Athai_64960	COG0745	RESPONSE REGULATOR receiver
Athai_64970	COG5002	protein histidine kinase activity
Athai_65010	COG0210	DNA helicase
Athai_65100	COG2267	carboxylic ester hydrolase activity
Athai_65170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Athai_65210	COG1522	sequence-specific DNA binding
Athai_65220	COG1834	amidinotransferase
Athai_65480	COG0717	Belongs to the dCTP deaminase family
Athai_65550	COG0247	lactate metabolic process
Athai_65550	COG2181	nitrate reductase activity
Athai_65570	COG0443	Heat shock 70 kDa protein
Athai_65580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Athai_65590	COG0484	heat shock protein binding
Athai_65600	COG0789	Transcriptional regulator
Athai_65630	COG0475	glutathione-regulated potassium exporter activity
Athai_65710	COG0542	response to heat
Athai_65740	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_65750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Athai_65760	COG1619	proteins homologs of microcin C7 resistance protein MccF
Athai_65770	COG0640	Transcriptional regulator
Athai_65790	COG0586	Pfam SNARE associated Golgi protein
Athai_65830	COG0667	Aldo Keto reductase
Athai_65840	COG1309	transcriptional regulator
Athai_65870	COG1355	regulation of microtubule-based process
Athai_65890	COG0191	fructose-bisphosphate aldolase activity
Athai_65930	COG1733	regulation of RNA biosynthetic process
Athai_65960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Athai_65970	COG0151	Belongs to the GarS family
Athai_66000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Athai_66010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Athai_66030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Athai_66040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Athai_66050	COG0047	phosphoribosylformylglycinamidine synthase activity
Athai_66060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Athai_66090	COG1131	(ABC) transporter
Athai_66160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Athai_66210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Athai_66270	COG1250	3-hydroxyacyl-CoA dehydrogenase
Athai_66280	COG1024	Enoyl-CoA hydratase
Athai_66320	COG2050	protein possibly involved in aromatic compounds catabolism
Athai_66360	COG2050	protein possibly involved in aromatic compounds catabolism
Athai_66370	COG2186	Transcriptional regulator
Athai_66400	COG0686	Belongs to the AlaDH PNT family
Athai_66460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Athai_66470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Athai_66540	COG1597	lipid kinase activity
Athai_66600	COG0640	Transcriptional regulator
Athai_66620	COG3415	Transposase
Athai_66620	COG2801	Transposase and inactivated derivatives
Athai_66630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Athai_66640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Athai_66650	COG2130	NADP-dependent
Athai_66660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Athai_66700	COG0673	inositol 2-dehydrogenase activity
Athai_66710	COG1609	Transcriptional regulator
Athai_66750	COG0765	amino acid transport
Athai_66760	COG0765	amino acid transport
Athai_66770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Athai_66790	COG0235	Class ii aldolase
Athai_66820	COG2197	response regulator
Athai_66870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Athai_66910	COG0667	Aldo Keto reductase
Athai_66920	COG1028	Short-chain dehydrogenase reductase Sdr
Athai_66990	COG1595	DNA-templated transcription, initiation
Athai_67030	COG1064	alcohol dehydrogenase
Athai_67040	COG0586	Pfam SNARE associated Golgi protein
Athai_67050	COG1007	ATP synthesis coupled electron transport
Athai_67070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Athai_67100	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Athai_67120	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Athai_67150	COG1309	transcriptional regulator
Athai_67250	COG2801	Transposase and inactivated derivatives
Athai_67400	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Athai_67410	COG2197	response regulator
Athai_67420	COG4585	Histidine kinase
Athai_67450	COG0477	Major facilitator Superfamily
Athai_67510	COG0277	FAD linked oxidase domain protein
Athai_67590	COG0457	Tetratricopeptide repeat
Athai_67590	COG0463	Glycosyl transferase, family 2
Athai_67620	COG0142	geranyltranstransferase activity
Athai_67630	COG0702	epimerase
Athai_67640	COG0300	oxidoreductase activity
Athai_67720	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Athai_67730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Athai_67750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Athai_67810	COG0277	FAD linked oxidase domain protein
Athai_67860	COG0589	response to stress
Athai_67920	COG0439	Biotin carboxylase
Athai_67930	COG3387	PFAM Glycoside hydrolase 15-related
Athai_67940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Athai_67960	COG1072	(Pantothenic acid kinase))
Athai_68070	COG1309	transcriptional regulator
Athai_68190	COG1793	dna ligase
Athai_68190	COG3285	dna ligase
Athai_68200	COG3285	dna ligase
Athai_68200	COG1793	dna ligase
Athai_68210	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Athai_68230	COG1366	Belongs to the anti-sigma-factor antagonist family
Athai_68270	COG2267	carboxylic ester hydrolase activity
Athai_68310	COG0577	efflux transmembrane transporter activity
Athai_68320	COG1136	(ABC) transporter
Athai_68370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Athai_68410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes