locus-tag	class	description
B6G06_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
B6G06_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
B6G06_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
B6G06_00020	ENOG4105K7N	UPF0232 protein
B6G06_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B6G06_00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B6G06_00070	ENOG4108U4N	(sortase) family
B6G06_00075	ENOG4105D9P	serine threonine protein kinase
B6G06_00080	ENOG4107TPY	serine threonine protein kinase
B6G06_00085	ENOG4105CJN	penicillin-binding protein
B6G06_00100	ENOG4105HZM	Fha domain containing protein
B6G06_00105	ENOG4105TV9	FHA Domain-Containing protein
B6G06_00125	ENOG4105D22	carbon starvation protein
B6G06_00135	ENOG4107ZR7	Membrane
B6G06_00140	ENOG4107QTF	adenylosuccinate lyase
B6G06_00165	ENOG4105CIH	Imidazole acetol-phosphate transaminase
B6G06_00180	ENOG4105KME	endoribonuclease L-psp
B6G06_00195	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B6G06_00205	ENOG4105C4Y	ABC transporter
B6G06_00210	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B6G06_00215	ENOG4105GR3	Histidine kinase
B6G06_00240	ENOG4107TE5	Lipid kinase
B6G06_00245	ENOG4105C5Q	Transcriptional regulator
B6G06_00250	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
B6G06_00255	ENOG410667J	hydrolase
B6G06_00265	ENOG4107QKS	N-acylglucosamine 2-epimerase
B6G06_00295	ENOG4105C28	cystathionine
B6G06_00330	ENOG4105WH1	Two component transcriptional regulator luxr family
B6G06_00340	ENOG4105DA5	(ABC) transporter
B6G06_00355	ENOG4105DF6	Fe-S oxidoreductase
B6G06_00375	ENOG4108UCS	ABC, transporter
B6G06_00465	ENOG4105ETE	Transcriptional regulator (LacI family
B6G06_00470	ENOG4105CNT	hydrolase family 2
B6G06_00475	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B6G06_00505	ENOG4108RVA	ribokinase
B6G06_00515	ENOG4105KJF	protein tyrosine phosphatase
B6G06_00525	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
B6G06_00530	ENOG4108UMI	ABC transporter, permease
B6G06_00535	ENOG4105D01	(LipO)protein
B6G06_00540	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
B6G06_00545	ENOG4105C94	Transporter
B6G06_00550	ENOG4108Z6B	deaminase
B6G06_00555	ENOG4108UW5	maltose o-acetyltransferase
B6G06_00565	ENOG4105CQ7	ATP-dependent helicase
B6G06_00585	ENOG4105C2W	permease
B6G06_00600	ENOG4105CFG	Acts as a chaperone (By similarity)
B6G06_00605	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B6G06_00610	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
B6G06_00615	ENOG4105KNI	merR family transcriptional Regulator
B6G06_00625	ENOG4105CRK	lysyL-tRNA synthetase
B6G06_00650	ENOG4106F60	Histidine kinase
B6G06_00655	ENOG4105F44	Two component transcriptional regulator, winged helix family
B6G06_00665	ENOG4108TVX	serine protease
B6G06_00670	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B6G06_00675	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B6G06_00680	ENOG4105ETE	Transcriptional regulator (LacI family
B6G06_00690	ENOG4108HKT	sucrose-6-phosphate hydrolase
B6G06_00700	ENOG4108EQA	pts system
B6G06_00705	ENOG4105ETZ	PTS System
B6G06_00710	ENOG4105F3R	pts system mannose fructose sorbose family iid
B6G06_00735	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
B6G06_00740	ENOG4105C8N	cysteinyl-tRNA synthetase
B6G06_00745	ENOG4105C2N	RNA methyltransferase TrmH family group 3
B6G06_00790	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
B6G06_00800	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
B6G06_00815	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
B6G06_00830	ENOG4105EB3	Histidine kinase
B6G06_00835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B6G06_00855	ENOG4105CFI	type iii restriction protein res subunit
B6G06_00885	ENOG4105C7N	Xanthine uracil vitamin C permease
B6G06_00905	ENOG4105K4H	Nlp p60 protein
B6G06_00930	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
B6G06_00940	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
B6G06_00990	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
B6G06_00995	ENOG4105F8V	Hydrolase, tatD family
B6G06_01015	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
B6G06_01020	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
B6G06_01025	ENOG4105C5H	ABC transporter
B6G06_01035	ENOG4105D9P	serine threonine protein kinase
B6G06_01065	ENOG41067SE	Tetr family transcriptional regulator
B6G06_01080	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
B6G06_01100	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
B6G06_01150	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
B6G06_01155	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
B6G06_01185	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
B6G06_01205	ENOG4105FF2	Type I DHQase
B6G06_01215	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
B6G06_01220	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
B6G06_01225	ENOG4105WH1	Two component transcriptional regulator luxr family
B6G06_01230	ENOG4105BZU	Histidine kinase
B6G06_01240	ENOG4105CJ1	ABC, transporter
B6G06_01250	ENOG4108V1T	peptidylprolyl cis-trans isomerase
B6G06_01255	ENOG4105C01	Dihydroxy-acid dehydratase
B6G06_01265	ENOG4105C7B	Threonine dehydratase
B6G06_01275	ENOG4108YYH	Nadph-dependent fmn reductase
B6G06_01280	ENOG4108YYH	Nadph-dependent fmn reductase
B6G06_01295	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
B6G06_01300	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
B6G06_01310	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
B6G06_01315	ENOG4105D7K	pfkb domain protein
B6G06_01320	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B6G06_01325	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B6G06_01330	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
B6G06_01345	ENOG4105C3G	gtp-binding protein
B6G06_01405	ENOG4105DFM	M18 family aminopeptidase
B6G06_01410	ENOG4105K5B	UPF0225 protein
B6G06_01415	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B6G06_01435	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B6G06_01440	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B6G06_01450	ENOG4105VKD	bioY protein
B6G06_01455	ENOG4105DEN	Luciferase family
B6G06_01465	ENOG4105CI3	gtp-binding protein typa
B6G06_01475	ENOG4108Z4U	Ferredoxin
B6G06_01500	ENOG4108RH7	phosphoglycerate mutase
B6G06_01520	ENOG4105DWV	Homoserine O-trans-acetylase
B6G06_01525	ENOG4108IQK	o-acetylhomoserine
B6G06_01535	ENOG4105F0N	pyrophosphate phospho-hydrolase
B6G06_01555	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
B6G06_01560	ENOG4105EUJ	GTP cyclohydrolase i
B6G06_01565	ENOG4105EEI	dihydropteroate synthase
B6G06_01595	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
B6G06_01600	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
B6G06_01610	ENOG4105CRK	lysyL-tRNA synthetase
B6G06_01625	ENOG4105DEI	Mannitol dehydrogenase
B6G06_01630	ENOG4105IE8	Alpha-ketoglutarate permease
B6G06_01640	ENOG41080R8	Conserved Protein
B6G06_01650	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
B6G06_01655	ENOG4105DAA	L-lactate
B6G06_01670	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
B6G06_01675	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
B6G06_01680	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
B6G06_01685	ENOG4105DKT	Transcriptional regulator
B6G06_01695	ENOG4107YVI	ribose 5-phosphate isomerase
B6G06_01705	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
B6G06_01710	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
B6G06_01725	ENOG4105DKT	Transcriptional regulator
B6G06_01750	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
B6G06_01770	ENOG4105CM4	permease protein
B6G06_01775	ENOG4108IPW	abc transporter atp-binding protein
B6G06_01790	ENOG4105H6Q	decarboxylase
B6G06_01805	ENOG4107RGD	Major Facilitator superfamily
B6G06_01820	ENOG4105CMT	Dihydroxyacetone kinase
B6G06_01825	ENOG4108UTZ	Dihydroxyacetone kinase
B6G06_01830	ENOG4107WI4	Aldose-1-epimerase
B6G06_01840	ENOG4105CZN	Potassium uptake protein
B6G06_01855	ENOG4107R4N	Cell wall formation (By similarity)
B6G06_01900	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
B6G06_01905	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
B6G06_01910	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
B6G06_01920	ENOG4105CDV	Ompa motb domain protein
B6G06_01935	ENOG4108VZM	50s ribosomal protein L10
B6G06_01940	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
B6G06_01945	ENOG4105E9K	Isocitrate dehydrogenase
B6G06_01965	ENOG4105EMN	RNA polymerase sigma factor
B6G06_01970	ENOG4105WMN	AntiSigma factor
B6G06_01980	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
B6G06_01985	ENOG4105C37	(CBS) domain
B6G06_02055	ENOG4105C75	arginyL-tRNA synthetase
B6G06_02060	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
B6G06_02065	ENOG4105D6E	homoserine dehydrogenase
B6G06_02070	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
B6G06_02085	ENOG4105VFB	Binds the 23S rRNA (By similarity)
B6G06_02090	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
B6G06_02095	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
B6G06_02155	ENOG4105CG3	alpha amylase, catalytic region
B6G06_02160	ENOG4105CTQ	phosphohexokinase
B6G06_02165	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
B6G06_02185	ENOG4105C29	acyl-CoA thioesterase
B6G06_02190	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
B6G06_02195	ENOG4105CI1	PTS System
B6G06_02205	ENOG4105C5Y	PTS System
B6G06_02215	ENOG4105FDP	GntR family transcriptional regulator
B6G06_02235	ENOG4105C9K	Endothelin-converting enzyme 1
B6G06_02240	ENOG4108YZG	isomerase
B6G06_02245	ENOG4105BZW	Glycerate kinase
B6G06_02255	ENOG4105D7W	serine acetyltransferase
B6G06_02265	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
B6G06_02270	ENOG41067C8	50S ribosomal protein L32
B6G06_02315	ENOG4107QRT	dEAD DEAH box helicase
B6G06_02350	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
B6G06_02360	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
B6G06_02375	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
B6G06_02380	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
B6G06_02395	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
B6G06_02400	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
B6G06_02420	ENOG4105II7	pyrroline-5-carboxylate reductase
B6G06_02425	ENOG4105EMU	Dehydrogenase
B6G06_02435	ENOG410635A	Membrane
B6G06_02440	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
B6G06_02455	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
B6G06_02460	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
B6G06_02465	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
B6G06_02480	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
B6G06_02490	ENOG4108UW5	maltose o-acetyltransferase
B6G06_02500	ENOG4107YJ4	chain length determinant protein
B6G06_02505	ENOG4105D3Q	Sugar transferase
B6G06_02510	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
B6G06_02515	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
B6G06_02520	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
B6G06_02530	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
B6G06_02535	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B6G06_02540	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
B6G06_02570	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
B6G06_02575	ENOG4105DRS	transport system, permease
B6G06_02580	ENOG4105D7K	pfkb domain protein
B6G06_02585	ENOG4105ETE	Transcriptional regulator (LacI family
B6G06_02590	ENOG4105DWK	Membrane
B6G06_02595	ENOG4105D0C	transport protein
B6G06_02610	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
B6G06_02620	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
B6G06_02625	ENOG4105CM2	brancheD-chain amino acid aminotransferase
B6G06_02630	ENOG4107SJB	teichoic acid biosynthesis
B6G06_02635	ENOG4108KGH	TRANSCRIPTIONal
B6G06_02645	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
B6G06_02650	ENOG4105K64	Glycosyl transferase, family 2
B6G06_02675	ENOG4105EY8	ABC transporter
B6G06_02695	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
B6G06_02705	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
B6G06_02720	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
B6G06_02735	ENOG4105FDK	ABC transporter
B6G06_02745	ENOG4107YH6	single-stranded DNA-binding protein
B6G06_02755	ENOG4105CAK	Cell division ATP-binding protein ftsE
B6G06_02760	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
B6G06_02770	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
B6G06_02780	ENOG4105FDP	GntR family transcriptional regulator
B6G06_02785	ENOG4108J59	Extracellular solute-binding protein, family 5
B6G06_02800	ENOG4108JQ7	(ABC) transporter
B6G06_02810	ENOG4105DKQ	ROK family
B6G06_02815	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
B6G06_02820	ENOG4108426	dNA-binding protein
B6G06_02825	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
B6G06_02845	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
B6G06_02855	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
B6G06_02860	ENOG4108RQ5	Beta-lactamase domain-containing protein
B6G06_02870	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
B6G06_02875	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
B6G06_02915	ENOG410901E	Membrane
B6G06_02920	ENOG4108IQI	permease
B6G06_02925	ENOG4107QK5	Homocysteine s-methyltransferase
B6G06_02935	ENOG4105EBR	Carboxylesterase
B6G06_02965	ENOG4105BZG	amino acid carrier protein
B6G06_02970	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
B6G06_02975	ENOG4105C87	Aminotransferase class I and II
B6G06_02980	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
B6G06_03010	ENOG4105CN5	Metallo-Beta-Lactamase
B6G06_03020	ENOG4107QZI	cell division protein FtsK
B6G06_03030	ENOG4105CEV	competence damage-inducible protein
B6G06_03035	ENOG4105WBV	Transcriptional regulator
B6G06_03045	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
B6G06_03050	ENOG4105KC9	Modulates RecA activity (By similarity)
B6G06_03055	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
B6G06_03065	ENOG4105DRS	transport system, permease
B6G06_03080	ENOG4105E2R	ROK family
B6G06_03085	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
B6G06_03115	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
B6G06_03120	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
B6G06_03125	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
B6G06_03130	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
B6G06_03140	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
B6G06_03155	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
B6G06_03165	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
B6G06_03190	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B6G06_03195	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
B6G06_03205	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
B6G06_03220	ENOG4105CPF	Cell wall formation (By similarity)
B6G06_03230	ENOG4105VB9	50S ribosomal protein l28
B6G06_03235	ENOG4105DP4	dak2 domain fusion protein ylov
B6G06_03255	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
B6G06_03260	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
B6G06_03275	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
B6G06_03280	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
B6G06_03295	ENOG4108JJ8	(ABC) transporter
B6G06_03300	ENOG4108JJ9	ABC, transporter
B6G06_03305	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
B6G06_03310	ENOG4105C4M	(Ubiquinol oxidase) subunit I
B6G06_03315	ENOG4105C03	ribonuclease
B6G06_03320	ENOG4108W6G	cytochrome C
B6G06_03335	ENOG4107QIV	Cytochrome c biogenesis protein
B6G06_03340	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
B6G06_03345	ENOG4105CRE	cytochrome C
B6G06_03355	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
B6G06_03360	ENOG4105K46	50S ribosomal protein l27
B6G06_03365	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B6G06_03370	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
B6G06_03380	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
B6G06_03385	ENOG4105E98	transcriptional regulator DeoR family
B6G06_03390	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
B6G06_03400	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
B6G06_03455	ENOG4107ZUX	Histidine triad (HIT) protein
B6G06_03460	ENOG4105C8T	Leucyl-tRNA synthetase
B6G06_03465	ENOG4105D7A	ATP-binding protein
B6G06_03470	ENOG4105EPR	degv family
B6G06_03485	ENOG4105D1H	recombination factor protein RarA
B6G06_03510	ENOG41084BS	50S ribosomal protein L35
B6G06_03515	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
B6G06_03520	ENOG4108RWN	rrna methyltransferase
B6G06_03525	ENOG4105CDA	abc transporter atp-binding protein
B6G06_03530	ENOG4105EAB	amino acid AbC transporter
B6G06_03535	ENOG4105EAD	ABC transporter
B6G06_03540	ENOG4105DRP	amino acid AbC transporter
B6G06_03550	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
B6G06_03555	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
B6G06_03565	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
B6G06_03570	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
B6G06_03575	ENOG4105CAS	nag kinase
B6G06_03580	ENOG4105C8Y	Acetylornithine aminotransferase
B6G06_03585	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
B6G06_03590	ENOG4105CDH	Citrulline--aspartate ligase
B6G06_03600	ENOG4105CH7	arginosuccinase
B6G06_03605	ENOG4108VX5	3-methyladenine DNA glycosylase
B6G06_03615	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
B6G06_03640	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
B6G06_03655	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
B6G06_03660	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
B6G06_03690	ENOG4105ECY	inositol monophosphatase
B6G06_03705	ENOG4105DIW	FeS assembly protein SUFB
B6G06_03715	ENOG4105C3K	feS assembly ATPase SufC
B6G06_03725	ENOG4107YH3	SUF system FeS assembly protein, NifU family
B6G06_03730	ENOG4105VG1	fes assembly suf system protein
B6G06_03745	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
B6G06_03750	ENOG4105CPC	Aldo Keto reductase
B6G06_03760	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
B6G06_03765	ENOG4105BZW	Glycerate kinase
B6G06_03780	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
B6G06_03785	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
B6G06_03810	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
B6G06_03835	ENOG4108IJ0	Aspartate ammonia-lyase
B6G06_03840	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
B6G06_03880	ENOG4105EGD	dinuclear metal center protein, YbgI family
B6G06_03890	ENOG4107XFJ	UPF0246 protein
B6G06_03915	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
B6G06_03920	ENOG4105C5F	glutamine synthetase
B6G06_03925	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
B6G06_03935	ENOG4108JEH	abc transporter atp-binding protein
B6G06_03940	ENOG4105E5Q	amino acid AbC transporter
B6G06_03950	ENOG4105C5F	glutamine synthetase
B6G06_03960	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
B6G06_03965	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
B6G06_03985	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
B6G06_04005	ENOG4105C6N	Formate acetyltransferase
B6G06_04060	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
B6G06_04070	ENOG4105C22	threonyL-tRNA synthetase
B6G06_04080	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
B6G06_04085	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
B6G06_04090	ENOG4105E2K	Glycosyl transferase (Group 1
B6G06_04105	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
B6G06_04110	ENOG4105CDY	transcriptional regulatory protein
B6G06_04115	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
B6G06_04120	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
B6G06_04125	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
B6G06_04135	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B6G06_04140	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B6G06_04145	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
B6G06_04150	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
B6G06_04160	ENOG4105C99	atpase involved in dna repair
B6G06_04180	ENOG4105CUT	histidyl-tRNA synthetase
B6G06_04210	ENOG4105C9M	aspartyl-trna synthetase
B6G06_04220	ENOG41080HT	Transcriptional regulator, arsr family
B6G06_04225	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
B6G06_04230	ENOG4107R13	MMPL domain protein
B6G06_04245	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
B6G06_04250	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
B6G06_04255	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
B6G06_04265	ENOG4105E2X	shikimate dehydrogenase
B6G06_04270	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
B6G06_04275	ENOG4105D49	3-dehydroquinate synthase
B6G06_04290	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
B6G06_04295	ENOG410803B	Involved in the transcription termination process (By similarity)
B6G06_04305	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
B6G06_04310	ENOG4105CXT	aspartate transcarbamylase
B6G06_04315	ENOG4105CD3	dihydroorotase
B6G06_04320	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
B6G06_04325	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
B6G06_04330	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
B6G06_04340	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
B6G06_04345	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
B6G06_04355	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
B6G06_04375	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
B6G06_04385	ENOG4105DJV	ribulose-phosphate 3-epimerase
B6G06_04400	ENOG4108JIK	carboxylase
B6G06_04405	ENOG4105D8K	carboxyl transferase
B6G06_04410	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
B6G06_04415	ENOG4105CK7	Sodium proline symporter
B6G06_04425	ENOG4108RWI	nicotinamidase
B6G06_04435	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
B6G06_04440	ENOG4107XKF	NMT1 THI5 Like Domain Protein
B6G06_04445	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
B6G06_04450	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
B6G06_04475	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
B6G06_04480	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
B6G06_04495	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
B6G06_04500	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
B6G06_04520	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
B6G06_04535	ENOG4105ETE	Transcriptional regulator (LacI family
B6G06_04540	ENOG4105C5Y	PTS System
B6G06_04545	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
B6G06_04565	ENOG4108UW8	fha domain-containing protein
B6G06_04570	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
B6G06_04590	ENOG4107QM2	Aldo Keto reductase
B6G06_04610	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
B6G06_04655	ENOG4107QP8	phosphohexose isomerase
B6G06_04660	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
B6G06_04675	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
B6G06_04680	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
B6G06_04700	ENOG4105CP7	Triose-phosphate isomerase
B6G06_04705	ENOG4105BZA	Phosphoglycerate kinase
B6G06_04710	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
B6G06_04715	ENOG4105CIE	May be required for sporulation (By similarity)
B6G06_04725	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
B6G06_04735	ENOG4105CID	antiterminator
B6G06_04745	ENOG4105C5Y	PTS System
B6G06_04755	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
B6G06_04785	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
B6G06_04790	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
B6G06_04795	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B6G06_04835	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
B6G06_04840	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
B6G06_04850	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
B6G06_04860	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
B6G06_04880	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
B6G06_04885	ENOG4105DK0	Indole-3-glycerol phosphate synthase
B6G06_04890	ENOG4105EPD	Oligopeptide transporter, Opt family
B6G06_04910	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
B6G06_04920	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
B6G06_04930	ENOG4105E5F	proteasome
B6G06_04935	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
B6G06_04945	ENOG4105C2C	drug resistance transporter, Bcr CflA
B6G06_04960	ENOG4105CUC	YeeE YedE family protein
B6G06_04970	ENOG4105CPC	Aldo Keto reductase
B6G06_04980	ENOG4107QN2	dihydrolipoyl dehydrogenase
B6G06_05005	ENOG4105DSB	aldose 1-epimerase
B6G06_05015	ENOG4105C0B	DNA polymerase III (alpha subunit)
B6G06_05020	ENOG4108IQI	permease
B6G06_05040	ENOG4108V1U	phospholipid-binding protein
B6G06_05045	ENOG4105EMU	Dehydrogenase
B6G06_05050	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
B6G06_05055	ENOG4107QM5	aconitate hydratase
B6G06_05060	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
B6G06_05065	ENOG4105C0X	amino acid
B6G06_05070	ENOG4107VEG	TrkA-N domain protein
B6G06_05110	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B6G06_05120	ENOG4105CPN	adenine deaminase
B6G06_05135	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B6G06_05150	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B6G06_05170	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
B6G06_05215	ENOG4105C5H	ABC transporter
B6G06_05240	ENOG4105DKW	ABC transporter
B6G06_05250	ENOG4107QPH	glycogen) synthase
B6G06_05255	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
B6G06_05260	ENOG4105EAC	phosphoserine phosphatase
B6G06_05290	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
B6G06_05305	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B6G06_05310	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
B6G06_05315	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
B6G06_05320	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
B6G06_05325	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
B6G06_05345	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
B6G06_05350	ENOG4105C9A	Phoh family
B6G06_05365	ENOG4105CIG	ABC transporter
B6G06_05375	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
B6G06_05380	ENOG4105DFA	alanine racemase domain protein
B6G06_05385	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
B6G06_05390	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
B6G06_05400	ENOG4105CXY	transporter
B6G06_05410	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
B6G06_05430	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
B6G06_05440	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
B6G06_05455	ENOG4105CRQ	synthase (Component I)
B6G06_05460	ENOG4105RGK	anthranilate synthase component ii
B6G06_05465	ENOG4108I0Q	anthranilate phosphoribosyltransferase
B6G06_05475	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
B6G06_05490	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
B6G06_05495	ENOG4105DPH	UPF0371 protein
B6G06_05515	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
B6G06_05520	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
B6G06_05530	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
B6G06_05535	ENOG4105CIH	Imidazole acetol-phosphate transaminase
B6G06_05540	ENOG4105EEQ	Na H antiporter
B6G06_05550	ENOG4105C9U	ATP-dependent DNA helicase RecQ
B6G06_05565	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
B6G06_05585	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
B6G06_05605	ENOG410848D	S4 domain protein YaaA
B6G06_05610	ENOG4105C0B	DNA polymerase III (alpha subunit)
B6G06_05640	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
B6G06_05645	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
B6G06_05650	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
B6G06_05660	ENOG4105DFU	Cell wall formation (By similarity)
B6G06_05670	ENOG4105CNI	cell division protein FtsW
B6G06_05675	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
B6G06_05680	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
B6G06_05690	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
B6G06_05695	ENOG4105CJN	penicillin-binding protein
B6G06_05705	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
B6G06_05710	ENOG4108V6E	Cell division protein mraZ
B6G06_05720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
B6G06_05740	ENOG4105CEY	Amp-dependent synthetase and ligase
B6G06_05750	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B6G06_05765	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
B6G06_05770	ENOG4105C1V	Peptidase, M16
B6G06_05775	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
B6G06_05780	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
B6G06_05800	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
B6G06_05805	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
B6G06_05820	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
B6G06_05835	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
B6G06_05845	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
B6G06_05855	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
B6G06_05860	ENOG4105DZP	Membrane-associated zinc metalloprotease
B6G06_05865	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
B6G06_05875	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
B6G06_05885	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
B6G06_05890	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
B6G06_05905	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
B6G06_05910	ENOG4105CE9	30S ribosomal protein S2
B6G06_05920	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B6G06_05930	ENOG4105C0P	Mg chelatase subunit ChlI
B6G06_05935	ENOG4105VFF	UPF0102 protein
B6G06_05945	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
B6G06_05960	ENOG4107QYR	Signal peptidase i
B6G06_05965	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
B6G06_05970	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
B6G06_05985	ENOG4105CPC	Aldo Keto reductase
B6G06_05990	ENOG41082KU	UPF0109 protein
B6G06_05995	ENOG4105K5M	30s ribosomal protein S16
B6G06_06005	ENOG4108M15	ABC transporter
B6G06_06015	ENOG4105BZU	Histidine kinase
B6G06_06020	ENOG4108S01	response regulator
B6G06_06030	ENOG4107TXC	Transcriptional regulator
B6G06_06035	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
B6G06_06040	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
B6G06_06045	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
B6G06_06050	ENOG4105EC2	ftsk spoIIIe
B6G06_06080	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
B6G06_06085	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
B6G06_06095	ENOG4107QNK	)-transporter
B6G06_06105	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
B6G06_06110	ENOG4105ETE	Transcriptional regulator (LacI family
B6G06_06130	ENOG4108IJ8	ABC transporter
B6G06_06145	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
B6G06_06150	ENOG4105C9Q	fumarate hydratase class II
B6G06_06160	ENOG4105DJZ	UPF0182 protein
B6G06_06215	ENOG41060M0	Crispr-associated protein, cse4 family
B6G06_06220	ENOG4108VWQ	crispr-associated protein
B6G06_06230	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
B6G06_06245	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
B6G06_06250	ENOG4105C10	Electron transfer flavoprotein
B6G06_06265	ENOG4105C31	Tryptophanyl-tRNA synthetase
B6G06_06270	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
B6G06_06285	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
B6G06_06315	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
B6G06_06330	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
B6G06_06335	ENOG4105BZ1	(ABC) transporter
B6G06_06340	ENOG4105BZ1	(ABC) transporter
B6G06_06360	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
B6G06_06365	ENOG4105C5Q	Transcriptional regulator
B6G06_06435	ENOG4105C1J	atp-dependent rna helicase
B6G06_06460	ENOG4105CJW	magnesium transporter
B6G06_06475	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
B6G06_06490	ENOG4108URH	decarboxylase
B6G06_06495	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
B6G06_06500	ENOG4107RPQ	ABC transporter
B6G06_06510	ENOG4105DIK	(ABC) transporter
B6G06_06515	ENOG4107SIG	periplasmic solute binding protein
B6G06_06520	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
B6G06_06535	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
B6G06_06545	ENOG4105CGK	Exodeoxyribonuclease III
B6G06_06555	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
B6G06_06560	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
B6G06_06570	ENOG4105KDC	50s ribosomal protein l28
B6G06_06575	ENOG4105W0E	50S ribosomal protein L33
B6G06_06580	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
B6G06_06585	ENOG4105NRA	50s ribosomal protein l31 type b
B6G06_06590	ENOG4108638	50S ribosomal protein L36
B6G06_06595	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
B6G06_06605	ENOG4108JJB	ABC transporter
B6G06_06615	ENOG4105KI2	Urea amidohydrolase subunit beta
B6G06_06620	ENOG4105CQM	Urea amidohydrolase subunit alpha
B6G06_06630	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
B6G06_06660	ENOG4105CE4	GlcNAc 6-P deacetylase
B6G06_06670	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
B6G06_06685	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
B6G06_06690	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
B6G06_06695	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
B6G06_06700	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
B6G06_06705	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B6G06_06710	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
B6G06_06715	ENOG4105ZA1	atp synthase
B6G06_06720	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
B6G06_06730	ENOG4105ESV	Glycosyl transferase, family 4
B6G06_06735	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
B6G06_06745	ENOG4105WH1	Two component transcriptional regulator luxr family
B6G06_06765	ENOG4105ECQ	AraC Family Transcriptional Regulator
B6G06_06780	ENOG4105CPC	Aldo Keto reductase
B6G06_06790	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B6G06_06810	ENOG4107QNK	)-transporter
B6G06_06815	ENOG4105F0H	myo-inositol catabolism protein
B6G06_06820	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
B6G06_06830	ENOG4105C26	Dehydrogenase
B6G06_06840	ENOG4105DH8	myo-inositol catabolism
B6G06_06855	ENOG4105FDP	GntR family transcriptional regulator
B6G06_06860	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
B6G06_06870	ENOG4105ETE	Transcriptional regulator (LacI family
B6G06_06875	ENOG4105ETE	Transcriptional regulator (LacI family
B6G06_06885	ENOG4107QNK	)-transporter
B6G06_06895	ENOG4105C54	Major Facilitator superfamily
B6G06_06900	ENOG4107P2S	Transcriptional regulator
B6G06_06925	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
B6G06_06935	ENOG410849S	phosphocarrier protein (HPr)
B6G06_06955	ENOG4108IUX	(ABC) transporter
B6G06_06960	ENOG4105WH1	Two component transcriptional regulator luxr family
B6G06_06965	ENOG4105BZU	Histidine kinase
B6G06_06970	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
B6G06_06975	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
B6G06_06985	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
B6G06_06990	ENOG4105E33	succinate dehydrogenase
B6G06_07020	ENOG4108097	ATP-binding protein
B6G06_07025	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
B6G06_07040	ENOG4105CS9	pantothenic acid kinase
B6G06_07045	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
B6G06_07050	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
B6G06_07060	ENOG4108UJD	30S ribosomal protein S9
B6G06_07065	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
B6G06_07070	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
B6G06_07085	ENOG4108ZT0	50S ribosomal protein l17
B6G06_07090	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B6G06_07095	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
B6G06_07100	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B6G06_07105	ENOG41067V7	50S ribosomal protein L36
B6G06_07110	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
B6G06_07120	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
B6G06_07130	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
B6G06_07135	ENOG410849U	50S ribosomal protein L30
B6G06_07140	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
B6G06_07150	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
B6G06_07160	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
B6G06_07165	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B6G06_07170	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
B6G06_07175	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
B6G06_07185	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
B6G06_07190	ENOG41082SA	50s ribosomal protein l29
B6G06_07195	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
B6G06_07200	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
B6G06_07205	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
B6G06_07210	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
B6G06_07215	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B6G06_07220	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
B6G06_07225	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
B6G06_07230	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
B6G06_07235	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
B6G06_07265	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
B6G06_07270	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
B6G06_07275	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
B6G06_07280	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
B6G06_07300	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
B6G06_07305	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B6G06_07310	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B6G06_07315	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
B6G06_07320	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
B6G06_07350	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B6G06_07370	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B6G06_07380	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B6G06_07395	ENOG4108IUE	nitrate reductase beta subunit
B6G06_07400	ENOG4105R3A	Nitrate reductase
B6G06_07420	ENOG4105TVJ	transport system, permease
B6G06_07425	ENOG4105DQ5	transport system permease protein
B6G06_07430	ENOG4108MES	Periplasmic binding protein
B6G06_07435	ENOG4105E0A	ABC, transporter
B6G06_07440	ENOG4105E2A	Dehydrogenase
B6G06_07445	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
B6G06_07450	ENOG4107TK4	histidinol-phosphate phosphatase
B6G06_07455	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
B6G06_07460	ENOG4107RH8	nuclease SbcCD subunit D
B6G06_07465	ENOG4105EYH	Exonuclease
B6G06_07505	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
B6G06_07515	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
B6G06_07525	ENOG4105BZU	Histidine kinase
B6G06_07530	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B6G06_07545	ENOG4108WQ6	secreted protein
B6G06_07550	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
B6G06_07590	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
B6G06_07600	ENOG4105EIP	mannose-6-phosphate isomerase
B6G06_07615	ENOG4106MCE	EamA-like transporter family
B6G06_07620	ENOG4105KPE	licD family
B6G06_07630	ENOG4108SHN	Glycosyl transferase, family 2
B6G06_07635	ENOG4105KPE	licD family
B6G06_07640	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
B6G06_07650	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
B6G06_07670	ENOG41084HI	prevent-host-death family
B6G06_07675	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
B6G06_07680	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
B6G06_07695	ENOG4105EY8	ABC transporter
B6G06_07700	ENOG4105MFV	ABC-2 type transporter
B6G06_07740	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
B6G06_07755	ENOG4107XU6	Glycosyl transferase (Group 1
B6G06_07790	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
B6G06_07795	ENOG4105CKK	Glycosyl transferase, family 2
B6G06_07815	ENOG4108KGH	TRANSCRIPTIONal
B6G06_07850	ENOG4105DQR	SNARE associated Golgi
B6G06_07860	ENOG4105BZU	Histidine kinase
B6G06_07875	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
B6G06_07880	ENOG4107WR6	Maf-like protein
B6G06_07895	ENOG4105WDJ	50S ribosomal protein L33
B6G06_07915	ENOG4108VPT	UPF0234 protein
B6G06_07920	ENOG4105D0M	Protease HtpX homolog
B6G06_07930	ENOG4105FDK	ABC transporter
B6G06_07935	ENOG4105CC5	ABC transporter
B6G06_07960	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B6G06_07970	ENOG4105D65	subunit l
B6G06_07975	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B6G06_07985	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B6G06_07990	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
B6G06_07995	ENOG4108IEH	NADH dehydrogenase subunit g
B6G06_08000	ENOG4107QIZ	NADH dehydrogenase
B6G06_08010	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B6G06_08015	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B6G06_08020	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B6G06_08030	ENOG4105P52	geranylgeranyl reductase
B6G06_08035	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
B6G06_08045	ENOG4105C0H	protease
B6G06_08050	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
B6G06_08055	ENOG4107TCW	O-succinylbenzoate synthase
B6G06_08060	ENOG4105CEU	Arginine dihydrolase
B6G06_08065	ENOG4107SIQ	Naphthoate synthase
B6G06_08070	ENOG4105R3P	Inner membrane protein yagU
B6G06_08080	ENOG4105K6V	RNA polymerase
B6G06_08115	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
B6G06_08125	ENOG4107RA4	Glycosyl transferase (Group 1
B6G06_08140	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B6G06_08145	ENOG4105D7T	ABC transporter
B6G06_08165	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
B6G06_08180	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
B6G06_08190	ENOG4107NHD	transcriptional regulator
B6G06_08215	ENOG4108ZHJ	Organic hydroperoxide resistance protein
B6G06_08220	ENOG4105K56	Transcriptional regulator
B6G06_08225	ENOG4105C1J	atp-dependent rna helicase
B6G06_08280	ENOG4105BZ1	(ABC) transporter
B6G06_08285	ENOG4105BZ1	(ABC) transporter
B6G06_08315	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
B6G06_08325	ENOG4105C6Z	Gluconate
B6G06_08330	ENOG4105ZXK	Dehydrogenase
B6G06_08340	ENOG4107YCY	Transcriptional regulator
B6G06_08355	ENOG4105DM4	PTS System
B6G06_08360	ENOG4105DE4	1-phosphofructokinase
B6G06_08365	ENOG4105E98	transcriptional regulator DeoR family
B6G06_08370	ENOG4105D82	Glutamate dehydrogenase
B6G06_08380	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
B6G06_08385	ENOG41088YS	Glycosyl transferase (Group 1
B6G06_08390	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
B6G06_08395	ENOG410839H	phosphoribosylformylglycinamidine synthase
B6G06_08410	ENOG4105C8V	SAICAR synthetase
B6G06_08415	ENOG4105C12	Phosphoribosylglycinamide synthetase
B6G06_08420	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
B6G06_08435	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
B6G06_08460	ENOG4107RCW	fructose-bisphosphate aldolase
B6G06_08480	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
B6G06_08490	ENOG4105EMU	Dehydrogenase
B6G06_08500	ENOG4108DBC	nitroreductase
B6G06_08510	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
B6G06_08525	ENOG4105DHP	deoxycytidine triphosphate deaminase
B6G06_08590	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
B6G06_08605	ENOG4108ZF3	Phosphatase
B6G06_08620	ENOG4108U8T	Mannosyltransferase
B6G06_08635	ENOG4105EN6	Membrane
B6G06_08645	ENOG4106N3A	copper homeostasis protein cutc
B6G06_08665	ENOG4105CQ7	ATP-dependent helicase
B6G06_08675	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
B6G06_08720	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
B6G06_08730	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
B6G06_08750	ENOG4105HDK	L-asparaginase
B6G06_08765	ENOG4107QRG	dna polymerase iii
B6G06_08775	ENOG4105CEU	Arginine dihydrolase
B6G06_08780	ENOG4105DBV	ornithine carbamoyltransferase
B6G06_08800	ENOG4105CSH	Transporter
B6G06_08810	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
B6G06_08820	ENOG4107SDU	Methyl-accepting chemotaxis
B6G06_08825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B6G06_08830	ENOG4105BZU	Histidine kinase
B6G06_08855	ENOG4105D3R	alkyl hydroperoxide reductase
B6G06_08870	ENOG4105U0R	haloacid dehalogenase-like hydrolase
B6G06_08905	ENOG4108UMN	azlc family
B6G06_08915	ENOG4105CPT	Alpha beta hydrolase
B6G06_08935	ENOG4105BZ4	penicillin-binding protein
B6G06_08945	ENOG4108PSK	reductase
B6G06_08975	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B6G06_09085	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
B6G06_09140	ENOG4105CNU	cell division protein FtsK
B6G06_09225	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
B6G06_09270	ENOG4105C79	DNA protecting protein DprA
B6G06_09295	ENOG4105CNU	cell division protein FtsK
B6G06_09310	ENOG4105K4H	Nlp p60 protein
B6G06_09395	ENOG4107TE5	Lipid kinase
B6G06_09410	ENOG4105CE1	Ferrous iron transport protein b
B6G06_09415	ENOG4105CE1	Ferrous iron transport protein b
B6G06_09425	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
B6G06_09430	ENOG4108IUK	alpha amylase, catalytic
B6G06_09445	ENOG4105EC2	ftsk spoIIIe
B6G06_09530	ENOG41080RH	Thioredoxin
B6G06_09535	ENOG4107JTW	chlorite dismutase
B6G06_09540	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
B6G06_09545	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
B6G06_09550	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
B6G06_09560	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
B6G06_09570	ENOG4105D52	delta-aminolevulinic acid dehydratase
B6G06_09575	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
B6G06_09585	ENOG4105CFH	Aspartokinase
B6G06_09590	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
B6G06_09640	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
B6G06_09645	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
B6G06_09660	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B6G06_09665	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
B6G06_09690	ENOG4105CG3	alpha amylase, catalytic region
B6G06_09710	ENOG4107QW3	Sucrose phosphorylase
B6G06_09730	ENOG4105DSF	transport protein
B6G06_09740	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
B6G06_09750	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
B6G06_09755	ENOG4105DWF	phosphomethylpyrimidine kinase
B6G06_09765	ENOG4107WGA	YidE YbjL
B6G06_09790	ENOG4105C85	amino acid
B6G06_09800	ENOG41083TI	Protein CrcB homolog
B6G06_09805	ENOG4108680	CrcB-like protein
B6G06_09815	ENOG4105DKQ	ROK family
B6G06_09825	ENOG4105DQ5	transport system permease protein
B6G06_09830	ENOG4105TVJ	transport system, permease
B6G06_09835	ENOG4105E0A	ABC, transporter
B6G06_09845	ENOG4105CDU	Replicative dna helicase
B6G06_09855	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
B6G06_09860	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
B6G06_09865	ENOG4107YH6	single-stranded DNA-binding protein
B6G06_09870	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
B6G06_09875	ENOG4105BZ4	penicillin-binding protein
B6G06_09885	ENOG4108JQ1	Dehydrogenase
B6G06_09890	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
B6G06_09905	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
B6G06_09925	ENOG4105C3M	thioredoxin reductase
B6G06_09930	ENOG4105K63	Thioredoxin
B6G06_09940	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B6G06_09945	ENOG4105CPF	Cell wall formation (By similarity)
B6G06_09955	ENOG4107QJE	Chromosome Partitioning Protein
B6G06_09960	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
B6G06_09970	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
B6G06_09975	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
B6G06_09980	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
B6G06_09985	ENOG41084CH	50S ribosomal protein l34