locus-tag	class	description
AoKodu_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AoKodu_00020	COG0592	DNA-directed DNA polymerase activity
AoKodu_00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AoKodu_00040	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AoKodu_00050	COG0187	DNA topoisomerase II activity
AoKodu_00060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AoKodu_00120	COG1476	TRANSCRIPTIONal
AoKodu_00230	COG3764	Sortase (surface protein transpeptidase)
AoKodu_00260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AoKodu_00270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AoKodu_00280	COG0360	Binds together with S18 to 16S ribosomal RNA
AoKodu_00300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AoKodu_00310	COG0359	binds to the 23S rRNA
AoKodu_00330	COG0305	Participates in initiation and elongation during chromosome replication
AoKodu_00430	COG1121	(ABC) transporter
AoKodu_00450	COG0351	phosphomethylpyrimidine kinase
AoKodu_00470	COG1733	regulation of RNA biosynthetic process
AoKodu_00490	COG1760	l-serine dehydratase
AoKodu_00580	COG1780	Probably involved in ribonucleotide reductase function
AoKodu_00590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AoKodu_00610	COG0385	Bile acid
AoKodu_00620	COG1072	(Pantothenic acid kinase))
AoKodu_00760	COG0672	)-iron permease
AoKodu_00780	COG2837	iron assimilation
AoKodu_00800	COG1309	transcriptional regulator
AoKodu_00840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AoKodu_00850	COG0561	phosphatase activity
AoKodu_00860	COG1653	transport
AoKodu_00980	COG0626	cystathionine gamma-synthase activity
AoKodu_00990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AoKodu_01040	COG1937	Protein conserved in bacteria
AoKodu_01060	COG2197	response regulator
AoKodu_01150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AoKodu_01310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AoKodu_01360	COG2813	Specifically methylates the guanine in position
AoKodu_01390	COG1950	PFAM Membrane protein of
AoKodu_01400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AoKodu_01420	COG2826	transposase and inactivated derivatives, IS30 family
AoKodu_01630	COG0463	Glycosyl transferase, family 2
AoKodu_01670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AoKodu_01700	COG2011	ABC-type metal ion transport system permease component
AoKodu_01710	COG1464	Belongs to the NlpA lipoprotein family
AoKodu_01720	COG1136	(ABC) transporter
AoKodu_01720	COG0577	efflux transmembrane transporter activity
AoKodu_01740	COG3311	Transcriptional regulator
AoKodu_01750	COG1569	PIN domain
AoKodu_01760	COG4585	Histidine kinase
AoKodu_01800	COG0732	type I restriction modification DNA specificity domain
AoKodu_01840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AoKodu_01850	COG0656	L-ascorbic acid biosynthetic process
AoKodu_01860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AoKodu_01870	COG0037	tRNA processing
AoKodu_01870	COG0590	tRNA wobble adenosine to inosine editing
AoKodu_01890	COG1643	Atp-dependent helicase
AoKodu_02270	COG1674	ftsk spoiiie
AoKodu_02310	COG2233	PERMEase
AoKodu_02350	COG1309	transcriptional regulator
AoKodu_02390	COG1609	Transcriptional regulator
AoKodu_02420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AoKodu_02460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AoKodu_02540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AoKodu_02560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AoKodu_02570	COG0113	porphobilinogen synthase activity
AoKodu_02590	COG0181	hydroxymethylbilane synthase activity
AoKodu_02610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AoKodu_02620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AoKodu_02630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AoKodu_02640	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AoKodu_02640	COG3253	May function as heme-dependent peroxidase
AoKodu_02650	COG2826	transposase and inactivated derivatives, IS30 family
AoKodu_02690	COG0783	Belongs to the Dps family
AoKodu_02770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AoKodu_02770	COG1918	ferrous iron import across plasma membrane
AoKodu_02800	COG1918	ferrous iron import across plasma membrane
AoKodu_02800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AoKodu_02840	COG1597	lipid kinase activity
AoKodu_02880	COG1028	Short-chain dehydrogenase reductase Sdr
AoKodu_02890	COG1408	metallophosphoesterase
AoKodu_02900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AoKodu_02950	COG1136	(ABC) transporter
AoKodu_02950	COG0577	efflux transmembrane transporter activity
AoKodu_02970	COG2267	carboxylic ester hydrolase activity
AoKodu_02980	COG3548	integral membrane protein
AoKodu_03000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AoKodu_03100	COG0450	alkyl hydroperoxide reductase
AoKodu_03110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AoKodu_03120	COG2890	protein-(glutamine-N5) methyltransferase activity
AoKodu_03170	COG2205	protein histidine kinase activity
AoKodu_03180	COG0745	RESPONSE REGULATOR receiver
AoKodu_03210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AoKodu_03210	COG1754	DNA topoisomerase type I activity
AoKodu_03230	COG0745	RESPONSE REGULATOR receiver
AoKodu_03240	COG0642	Histidine kinase
AoKodu_03250	COG2885	chlorophyll binding
AoKodu_03270	COG2188	Transcriptional regulator
AoKodu_03320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AoKodu_03330	COG0470	DNA polymerase III
AoKodu_03380	COG0252	asparaginase activity
AoKodu_03390	COG1113	amino acid transport
AoKodu_03410	COG0588	phosphoglycerate mutase activity
AoKodu_03430	COG5002	protein histidine kinase activity
AoKodu_03440	COG0745	RESPONSE REGULATOR receiver
AoKodu_03460	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AoKodu_03520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AoKodu_03580	COG2801	Transposase and inactivated derivatives
AoKodu_03670	COG1643	Atp-dependent helicase
AoKodu_03720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AoKodu_03730	COG2860	membrane
AoKodu_03880	COG0714	Associated with various cellular activities
AoKodu_04000	COG0717	Belongs to the dCTP deaminase family
AoKodu_04020	COG2176	DNA-directed DNA polymerase activity
AoKodu_04050	COG1028	Short-chain dehydrogenase reductase Sdr
AoKodu_04060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AoKodu_04070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AoKodu_04080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AoKodu_04090	COG0191	fructose-bisphosphate aldolase activity
AoKodu_04150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AoKodu_04250	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AoKodu_04320	COG0151	Belongs to the GarS family
AoKodu_04330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AoKodu_04370	COG0047	phosphoribosylformylglycinamidine synthase activity
AoKodu_04400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AoKodu_04410	COG2826	transposase and inactivated derivatives, IS30 family
AoKodu_04450	COG1090	epimerase
AoKodu_04470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AoKodu_04480	COG0737	Belongs to the 5'-nucleotidase family
AoKodu_04490	COG1349	DNA-binding transcription factor activity
AoKodu_04510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AoKodu_04510	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AoKodu_04510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AoKodu_04540	COG0557	exoribonuclease II activity
AoKodu_04570	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AoKodu_04580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AoKodu_04630	COG1132	(ABC) transporter
AoKodu_04640	COG1132	(ABC) transporter
AoKodu_04660	COG0577	efflux transmembrane transporter activity
AoKodu_04670	COG1136	(ABC) transporter
AoKodu_04690	COG1472	Belongs to the glycosyl hydrolase 3 family
AoKodu_04740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AoKodu_04780	COG1722	exodeoxyribonuclease VII activity
AoKodu_04790	COG1570	exodeoxyribonuclease VII activity
AoKodu_04800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AoKodu_04810	COG0833	amino acid
AoKodu_04840	COG1595	DNA-templated transcription, initiation
AoKodu_04900	COG2261	transglycosylase associated protein
AoKodu_04910	COG1322	Protein conserved in bacteria
AoKodu_04930	COG0012	GTP binding
AoKodu_05020	COG3549	Plasmid maintenance system killer
AoKodu_05040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AoKodu_05050	COG2873	o-acetylhomoserine
AoKodu_05080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AoKodu_05090	COG2027	D-alanyl-D-alanine carboxypeptidase
AoKodu_05110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AoKodu_05140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AoKodu_05150	COG0302	gtp cyclohydrolase
AoKodu_05170	COG0302	gtp cyclohydrolase
AoKodu_05200	COG2076	Multidrug Resistance protein
AoKodu_05220	COG2197	response regulator
AoKodu_05230	COG0577	efflux transmembrane transporter activity
AoKodu_05230	COG1136	(ABC) transporter
AoKodu_05240	COG1136	(ABC) transporter
AoKodu_05240	COG0577	efflux transmembrane transporter activity
AoKodu_05250	COG1136	(ABC) transporter
AoKodu_05250	COG0577	efflux transmembrane transporter activity
AoKodu_05260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AoKodu_05270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AoKodu_05320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AoKodu_05330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AoKodu_05350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AoKodu_05360	COG2207	Transcriptional regulator
AoKodu_05360	COG1917	Cupin 2, conserved barrel domain protein
AoKodu_05390	COG3599	regulation of cell shape
AoKodu_05430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AoKodu_05440	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AoKodu_05450	COG1120	ATPase activity
AoKodu_05460	COG4592	Periplasmic binding protein
AoKodu_05480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AoKodu_05540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AoKodu_05570	COG3104	oligopeptide transport
AoKodu_05580	COG3104	oligopeptide transport
AoKodu_05610	COG1556	Lactate utilization protein
AoKodu_05620	COG1139	Iron-sulfur cluster binding protein
AoKodu_05630	COG0247	lactate metabolic process
AoKodu_05660	COG1620	l-lactate permease
AoKodu_05670	COG2217	Heavy metal translocating P-type atpase
AoKodu_05680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AoKodu_05690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AoKodu_05700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AoKodu_05720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AoKodu_05770	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AoKodu_05790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AoKodu_05810	COG2814	Major facilitator Superfamily
AoKodu_05850	COG2376	Dihydroxyacetone kinase
AoKodu_05860	COG1461	Dihydroxyacetone kinase
AoKodu_05990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AoKodu_06010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AoKodu_06020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AoKodu_06060	COG0436	Aminotransferase
AoKodu_06070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AoKodu_06080	COG0250	Participates in transcription elongation, termination and antitermination
AoKodu_06090	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AoKodu_06100	COG0081	regulation of translation
AoKodu_06190	COG2885	chlorophyll binding
AoKodu_06210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AoKodu_06220	COG0049	tRNA binding
AoKodu_06230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AoKodu_06240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AoKodu_06280	COG0051	transcription antitermination factor activity, RNA binding
AoKodu_06290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AoKodu_06310	COG0089	rRNA binding
AoKodu_06320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AoKodu_06330	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AoKodu_06340	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AoKodu_06350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AoKodu_06360	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AoKodu_06370	COG0255	Belongs to the universal ribosomal protein uL29 family
AoKodu_06380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AoKodu_06390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AoKodu_06400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AoKodu_06410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AoKodu_06420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AoKodu_06430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AoKodu_06440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AoKodu_06450	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AoKodu_06460	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AoKodu_06470	COG1841	ribosomal large subunit assembly
AoKodu_06500	COG0563	adenylate kinase activity
AoKodu_06510	COG0024	Methionine aminopeptidase
AoKodu_06520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AoKodu_06530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AoKodu_06540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AoKodu_06550	COG0202	RNA polymerase activity
AoKodu_06590	COG1285	pathogenesis
AoKodu_06610	COG0101	tRNA pseudouridine synthase activity
AoKodu_06620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AoKodu_06630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AoKodu_06700	COG1396	sequence-specific DNA binding
AoKodu_06710	COG0596	Alpha beta hydrolase
AoKodu_06720	COG1072	(Pantothenic acid kinase))
AoKodu_06740	COG0736	holo-[acyl-carrier-protein] synthase activity
AoKodu_06760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AoKodu_06770	COG0802	atpase or kinase
AoKodu_06820	COG1053	succinate dehydrogenase
AoKodu_06830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AoKodu_06840	COG0546	phosphoglycolate phosphatase activity
AoKodu_06850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AoKodu_06870	COG1132	(ABC) transporter
AoKodu_06870	COG2375	cellular response to nickel ion
AoKodu_06880	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AoKodu_06900	COG2949	membrane
AoKodu_06910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AoKodu_06960	COG0516	GMP reductase activity
AoKodu_06970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AoKodu_06980	COG4975	Glucose uptake
AoKodu_07080	COG0328	RNA-DNA hybrid ribonuclease activity
AoKodu_07100	COG2197	response regulator
AoKodu_07110	COG4585	Histidine kinase
AoKodu_07140	COG1131	(ABC) transporter
AoKodu_07150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AoKodu_07210	COG1082	Xylose isomerase domain protein TIM barrel
AoKodu_07220	COG2814	Major facilitator Superfamily
AoKodu_07230	COG0673	inositol 2-dehydrogenase activity
AoKodu_07250	COG2017	converts alpha-aldose to the beta-anomer
AoKodu_07260	COG0673	inositol 2-dehydrogenase activity
AoKodu_07270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AoKodu_07280	COG2188	Transcriptional regulator
AoKodu_07310	COG3718	enzyme involved in inositol metabolism
AoKodu_07340	COG2814	Major facilitator Superfamily
AoKodu_07390	COG0519	Catalyzes the synthesis of GMP from XMP
AoKodu_07390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AoKodu_07430	COG1131	(ABC) transporter
AoKodu_07440	COG4585	Histidine kinase
AoKodu_07530	COG2267	carboxylic ester hydrolase activity
AoKodu_07550	COG3654	unkown
AoKodu_07570	COG1401	restriction endodeoxyribonuclease activity
AoKodu_07600	COG0693	protein deglycase activity
AoKodu_07640	COG2205	protein histidine kinase activity
AoKodu_07650	COG2197	response regulator
AoKodu_07670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AoKodu_07690	COG0356	it plays a direct role in the translocation of protons across the membrane
AoKodu_07710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AoKodu_07720	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AoKodu_07730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AoKodu_07740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AoKodu_07750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AoKodu_07760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AoKodu_07780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AoKodu_07830	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AoKodu_07920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AoKodu_07930	COG0254	rRNA binding
AoKodu_07940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AoKodu_07950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AoKodu_07960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AoKodu_07980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AoKodu_07990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AoKodu_08000	COG1621	beta-fructofuranosidase activity
AoKodu_08040	COG1254	Belongs to the acylphosphatase family
AoKodu_08060	COG0577	efflux transmembrane transporter activity
AoKodu_08060	COG1136	(ABC) transporter
AoKodu_08070	COG1136	(ABC) transporter
AoKodu_08070	COG0577	efflux transmembrane transporter activity
AoKodu_08090	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AoKodu_08100	COG1349	DNA-binding transcription factor activity
AoKodu_08160	COG1744	ABC transporter substrate-binding protein PnrA-like
AoKodu_08170	COG3845	ABC transporter
AoKodu_08180	COG4603	Belongs to the binding-protein-dependent transport system permease family
AoKodu_08190	COG1079	Belongs to the binding-protein-dependent transport system permease family
AoKodu_08250	COG0803	Belongs to the bacterial solute-binding protein 9 family
AoKodu_08260	COG1121	(ABC) transporter
AoKodu_08290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AoKodu_08300	COG1611	Belongs to the LOG family
AoKodu_08330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AoKodu_08360	COG2239	Acts as a magnesium transporter
AoKodu_08380	COG1082	Xylose isomerase domain protein TIM barrel
AoKodu_08410	COG0006	proline dipeptidase activity
AoKodu_08440	COG2095	MarC family integral membrane protein
AoKodu_08450	COG0513	Belongs to the DEAD box helicase family
AoKodu_08540	COG0114	fumarate hydratase activity
AoKodu_08580	COG0346	lactoylglutathione lyase activity
AoKodu_08600	COG1174	glycine betaine transport
AoKodu_08640	COG1733	regulation of RNA biosynthetic process
AoKodu_08660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AoKodu_08720	COG1674	ftsk spoiiie
AoKodu_08730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AoKodu_08750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AoKodu_08760	COG0154	amidase activity
AoKodu_08770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AoKodu_08800	COG2966	Psort location CytoplasmicMembrane, score
AoKodu_08810	COG0569	domain protein
AoKodu_08810	COG2985	domain, Protein
AoKodu_08840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AoKodu_08870	COG0473	3-isopropylmalate dehydrogenase activity
AoKodu_08910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AoKodu_08920	COG1316	TRANSCRIPTIONal
AoKodu_08930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AoKodu_08940	COG0463	Glycosyl transferase, family 2
AoKodu_08940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AoKodu_08950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AoKodu_08990	COG1216	Glycosyl transferase, family 2
AoKodu_09010	COG1134	teichoic acid transport
AoKodu_09050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AoKodu_09070	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AoKodu_09090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AoKodu_09110	COG0515	serine threonine protein kinase
AoKodu_09120	COG1716	ATPase activity
AoKodu_09120	COG1131	(ABC) transporter
AoKodu_09120	COG0842	Transport permease protein
AoKodu_09160	COG1162	GTPase activity
AoKodu_09170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AoKodu_09200	COG2884	Cell division ATP-binding protein ftsE
AoKodu_09210	COG2177	Part of the ABC transporter FtsEX involved in
AoKodu_09280	COG0747	negative chemotaxis
AoKodu_09310	COG0444	Belongs to the ABC transporter superfamily
AoKodu_09320	COG4608	Belongs to the ABC transporter superfamily
AoKodu_09350	COG1175	transmembrane transport
AoKodu_09370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AoKodu_09380	COG1940	carbohydrate kinase activity
AoKodu_09390	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AoKodu_09430	COG0363	glucosamine-6-phosphate deaminase activity
AoKodu_09470	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AoKodu_09490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AoKodu_09530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AoKodu_09540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AoKodu_09630	COG2801	Transposase and inactivated derivatives
AoKodu_09690	COG3304	Inner membrane component domain
AoKodu_09700	COG0833	amino acid
AoKodu_09710	COG2040	homocysteine
AoKodu_09760	COG1115	amino acid carrier protein
AoKodu_09770	COG1115	amino acid carrier protein
AoKodu_09780	COG1115	amino acid carrier protein
AoKodu_09790	COG1115	amino acid carrier protein
AoKodu_09800	COG0179	Fumarylacetoacetate (FAA) hydrolase
AoKodu_09820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AoKodu_09860	COG0726	polysaccharide deacetylase
AoKodu_09870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AoKodu_09880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AoKodu_09890	COG1674	ftsk spoiiie
AoKodu_09900	COG2843	Capsule synthesis protein
AoKodu_09920	COG1058	Belongs to the CinA family
AoKodu_09920	COG1546	Belongs to the CinA family
AoKodu_09930	COG1396	sequence-specific DNA binding
AoKodu_09950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AoKodu_09960	COG2137	regulation of response to DNA damage stimulus
AoKodu_09970	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AoKodu_09980	COG1252	NADH dehydrogenase
AoKodu_09990	COG0509	glycine decarboxylation via glycine cleavage system
AoKodu_10000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AoKodu_10010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AoKodu_10010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AoKodu_10020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AoKodu_10070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AoKodu_10080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AoKodu_10100	COG1114	Component of the transport system for branched-chain amino acids
AoKodu_10120	COG2813	Specifically methylates the guanine in position
AoKodu_10150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AoKodu_10180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AoKodu_10200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AoKodu_10240	COG0066	3-isopropylmalate dehydratase activity
AoKodu_10250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AoKodu_10270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AoKodu_10280	COG1181	Belongs to the D-alanine--D-alanine ligase family
AoKodu_10300	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AoKodu_10310	COG1461	Dihydroxyacetone kinase
AoKodu_10340	COG0235	Class ii aldolase
AoKodu_10360	COG1070	Carbohydrate kinase
AoKodu_10370	COG4154	Belongs to the RbsD FucU family
AoKodu_10380	COG0738	Major facilitator superfamily
AoKodu_10390	COG1609	Transcriptional regulator
AoKodu_10400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AoKodu_10430	COG0571	ribonuclease III activity
AoKodu_10440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AoKodu_10470	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AoKodu_10480	COG4988	ABC transporter
AoKodu_10490	COG1294	oxidase, subunit
AoKodu_10500	COG1271	oxidase subunit
AoKodu_10510	COG1530	ribonuclease E activity
AoKodu_10520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AoKodu_10530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AoKodu_10540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AoKodu_10550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AoKodu_10560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AoKodu_10580	COG0745	RESPONSE REGULATOR receiver
AoKodu_10590	COG2205	protein histidine kinase activity
AoKodu_10600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AoKodu_10630	COG1132	(ABC) transporter
AoKodu_10640	COG0297	glycogen (starch) synthase activity
AoKodu_10660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AoKodu_10670	COG1349	DNA-binding transcription factor activity
AoKodu_10690	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AoKodu_10710	COG0799	negative regulation of ribosome biogenesis
AoKodu_10720	COG0406	alpha-ribazole phosphatase activity
AoKodu_10730	COG2095	MarC family integral membrane protein
AoKodu_10760	COG0813	purine-nucleoside phosphorylase activity
AoKodu_10770	COG0733	neurotransmitter:sodium symporter activity
AoKodu_10830	COG0537	adenosine 5'-monophosphoramidase activity
AoKodu_10850	COG0495	leucyl-tRNA aminoacylation
AoKodu_10860	COG0433	COG0433 Predicted ATPase
AoKodu_10870	COG0438	transferase activity, transferring glycosyl groups
AoKodu_10890	COG1555	photosystem II stabilization
AoKodu_10920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AoKodu_10930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AoKodu_10930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AoKodu_10960	COG4868	Belongs to the UPF0371 family
AoKodu_10970	COG0268	Binds directly to 16S ribosomal RNA
AoKodu_10980	COG1122	ATPase activity
AoKodu_11050	COG0159	tryptophan synthase activity
AoKodu_11080	COG0512	Glutamine amidotransferase of anthranilate synthase
AoKodu_11090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AoKodu_11110	COG0481	GTPase activity
AoKodu_11130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AoKodu_11140	COG2807	transmembrane transport
AoKodu_11180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AoKodu_11210	COG1420	regulation of RNA biosynthetic process
AoKodu_11220	COG0484	heat shock protein binding
AoKodu_11230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AoKodu_11290	COG0842	Transport permease protein
AoKodu_11360	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AoKodu_11380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AoKodu_11390	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AoKodu_11390	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AoKodu_11390	COG0506	proline dehydrogenase activity
AoKodu_11400	COG3609	addiction module antidote protein, CC2985 family
AoKodu_11410	COG2337	Toxic component of a toxin-antitoxin (TA) module
AoKodu_11420	COG1476	TRANSCRIPTIONal
AoKodu_11440	COG1131	(ABC) transporter
AoKodu_11450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AoKodu_11460	COG1381	Involved in DNA repair and RecF pathway recombination
AoKodu_11470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AoKodu_11490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AoKodu_11520	COG0423	glycine-tRNA ligase activity
AoKodu_11570	COG0560	Phosphoserine phosphatase
AoKodu_11600	COG0297	glycogen (starch) synthase activity
AoKodu_11620	COG1119	ATPase activity
AoKodu_11680	COG0488	(ABC) transporter
AoKodu_11700	COG0545	Peptidyl-prolyl cis-trans isomerase
AoKodu_11760	COG0205	6-phosphofructokinase activity
AoKodu_11770	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AoKodu_11780	COG0515	serine threonine protein kinase
AoKodu_11780	COG2815	serine threonine protein kinase
AoKodu_11790	COG0142	geranyltranstransferase activity
AoKodu_11800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AoKodu_11840	COG0187	DNA topoisomerase II activity
AoKodu_11850	COG0454	-acetyltransferase
AoKodu_11850	COG0456	acetyltransferase
AoKodu_11870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AoKodu_11960	COG0569	domain protein
AoKodu_11970	COG0531	amino acid
AoKodu_11980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AoKodu_11990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AoKodu_12010	COG2161	toxin-antitoxin pair type II binding
AoKodu_12020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AoKodu_12050	COG4555	ABC transporter
AoKodu_12080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AoKodu_12090	COG4221	oxidoreductase activity
AoKodu_12100	COG1881	PFAM PEBP family protein
AoKodu_12130	COG0671	phosphoesterase, PA-phosphatase related
AoKodu_12140	COG1435	thymidine kinase activity
AoKodu_12180	COG0587	DNA-directed DNA polymerase activity
AoKodu_12250	COG0477	Major facilitator Superfamily
AoKodu_12270	COG0339	signal peptide processing
AoKodu_12280	COG0446	pyridine nucleotide-disulphide oxidoreductase
AoKodu_12300	COG0667	Aldo Keto reductase
AoKodu_12310	COG0425	Belongs to the sulfur carrier protein TusA family
AoKodu_12320	COG2391	methyltransferase activity
AoKodu_12350	COG0517	IMP dehydrogenase activity
AoKodu_12350	COG1994	Peptidase M50
AoKodu_12360	COG2837	iron assimilation
AoKodu_12390	COG1222	aaa ATPase
AoKodu_12400	COG4122	O-methyltransferase activity
AoKodu_12420	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AoKodu_12440	COG0107	imidazoleglycerol-phosphate synthase activity
AoKodu_12480	COG0134	indole-3-glycerol-phosphate synthase activity
AoKodu_12530	COG2050	protein possibly involved in aromatic compounds catabolism
AoKodu_12550	COG0539	negative regulation of cytoplasmic translation
AoKodu_12570	COG0237	dephospho-CoA kinase activity
AoKodu_12580	COG0556	nucleotide-excision repair
AoKodu_12650	COG0322	excinuclease ABC activity
AoKodu_12660	COG3585	molybdate ion transport
AoKodu_12680	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AoKodu_12690	COG1660	Displays ATPase and GTPase activities
AoKodu_12710	COG1481	regulation of sporulation
AoKodu_12720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AoKodu_12730	COG0126	phosphoglycerate kinase activity
AoKodu_12740	COG0149	triose-phosphate isomerase activity
AoKodu_12750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AoKodu_12790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AoKodu_12820	COG1160	GTP binding
AoKodu_12850	COG0166	Belongs to the GPI family
AoKodu_12860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AoKodu_12910	COG0363	glucosamine-6-phosphate deaminase activity
AoKodu_12950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AoKodu_12970	COG1716	ATPase activity
AoKodu_13010	COG0667	Aldo Keto reductase
AoKodu_13020	COG0443	Heat shock 70 kDa protein
AoKodu_13050	COG1621	beta-fructofuranosidase activity
AoKodu_13060	COG2190	(PTS) system
AoKodu_13060	COG1263	PTS System
AoKodu_13060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AoKodu_13070	COG1609	Transcriptional regulator
AoKodu_13090	COG1136	(ABC) transporter
AoKodu_13100	COG0577	efflux transmembrane transporter activity
AoKodu_13110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AoKodu_13130	COG0205	6-phosphofructokinase activity
AoKodu_13150	COG1216	Glycosyl transferase, family 2
AoKodu_13160	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AoKodu_13170	COG2354	Protein conserved in bacteria
AoKodu_13200	COG0805	protein transport
AoKodu_13210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AoKodu_13250	COG4585	Histidine kinase
AoKodu_13260	COG2197	response regulator
AoKodu_13270	COG1131	(ABC) transporter
AoKodu_13310	COG0140	phosphoribosyl-ATP diphosphatase activity
AoKodu_13320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AoKodu_13330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AoKodu_13340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AoKodu_13360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AoKodu_13380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AoKodu_13390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AoKodu_13400	COG4770	biotin carboxylase activity
AoKodu_13410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AoKodu_13430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AoKodu_13460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AoKodu_13470	COG0549	Belongs to the carbamate kinase family
AoKodu_13480	COG1834	amidinotransferase
AoKodu_13530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AoKodu_13550	COG1758	RNA polymerase activity
AoKodu_13560	COG0194	GDP metabolic process
AoKodu_13580	COG0284	orotidine-5'-phosphate decarboxylase activity
AoKodu_13590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AoKodu_13610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AoKodu_13620	COG0540	Belongs to the ATCase OTCase family
AoKodu_13630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AoKodu_13680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AoKodu_13690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AoKodu_13700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AoKodu_13720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AoKodu_13730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AoKodu_13750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AoKodu_13760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AoKodu_13770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AoKodu_13800	COG0009	L-threonylcarbamoyladenylate synthase
AoKodu_13840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AoKodu_13900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AoKodu_13900	COG1116	anion transmembrane transporter activity
AoKodu_13940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AoKodu_13960	COG0124	histidyl-tRNA synthetase
AoKodu_13980	COG0488	(ABC) transporter
AoKodu_13990	COG1196	nuclear chromosome segregation
AoKodu_14020	COG0789	Transcriptional regulator
AoKodu_14040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AoKodu_14050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AoKodu_14060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AoKodu_14070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AoKodu_14100	COG2255	four-way junction helicase activity
AoKodu_14110	COG0632	four-way junction helicase activity
AoKodu_14120	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AoKodu_14130	COG0217	transcriptional regulatory protein
AoKodu_14140	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AoKodu_14150	COG1051	belongs to the nudix hydrolase family
AoKodu_14160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AoKodu_14190	COG0438	transferase activity, transferring glycosyl groups
AoKodu_14230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AoKodu_14330	COG1882	Formate acetyltransferase
AoKodu_14350	COG1073	alpha beta
AoKodu_14360	COG0038	chloride channel
AoKodu_14380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AoKodu_14390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AoKodu_14400	COG0508	dehydrogenase complex catalyzes the overall conversion of
AoKodu_14440	COG0321	lipoyl(octanoyl) transferase activity
AoKodu_14450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AoKodu_14490	COG0765	amino acid transport
AoKodu_14510	COG0406	alpha-ribazole phosphatase activity
AoKodu_14520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AoKodu_14530	COG0174	glutamine synthetase
AoKodu_14540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AoKodu_14570	COG3022	response to hydroperoxide
AoKodu_14590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AoKodu_14600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AoKodu_14690	COG2197	response regulator
AoKodu_14830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AoKodu_14880	COG0436	Aminotransferase
AoKodu_14910	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AoKodu_14930	COG1027	Aspartate ammonia-lyase
AoKodu_14950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AoKodu_15000	COG0358	DNA primase activity
AoKodu_15040	COG2182	Extracellular solute-binding protein
AoKodu_15050	COG1175	transmembrane transport
AoKodu_15060	COG3833	ABC-type maltose transport systems, permease component
AoKodu_15110	COG0167	dihydroorotate dehydrogenase activity
AoKodu_15150	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AoKodu_15180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AoKodu_15210	COG3189	MarR family transcriptional regulator
AoKodu_15220	COG2151	metal-sulfur cluster biosynthetic enzyme
AoKodu_15230	COG0822	iron-sulfur transferase activity
AoKodu_15250	COG0396	ATPase activity
AoKodu_15260	COG0719	Fe-S assembly protein
AoKodu_15290	COG0494	nUDIX hydrolase
AoKodu_15350	COG0497	DNA recombination
AoKodu_15360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AoKodu_15390	COG0647	UMP catabolic process
AoKodu_15420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AoKodu_15460	COG2094	Belongs to the DNA glycosylase MPG family
AoKodu_15470	COG0165	Argininosuccinate lyase
AoKodu_15480	COG2116	formate transmembrane transporter activity
AoKodu_15490	COG0137	argininosuccinate synthase activity
AoKodu_15500	COG1438	arginine binding
AoKodu_15510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AoKodu_15520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AoKodu_15540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AoKodu_15570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AoKodu_15590	COG1131	(ABC) transporter
AoKodu_15650	COG0765	amino acid transport
AoKodu_15660	COG0765	amino acid transport
AoKodu_15670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AoKodu_15680	COG1126	abc transporter atp-binding protein
AoKodu_15710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AoKodu_15720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AoKodu_15730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AoKodu_15740	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AoKodu_15760	COG4133	protoheme IX ABC transporter activity
AoKodu_15800	COG0575	Belongs to the CDS family
AoKodu_15820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AoKodu_15830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AoKodu_15870	COG0131	Imidazoleglycerol-phosphate dehydratase
AoKodu_15890	COG0025	NhaP-type Na H and K H
AoKodu_15930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AoKodu_15950	COG1215	transferase activity, transferring glycosyl groups
AoKodu_15970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AoKodu_15980	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AoKodu_16020	COG2501	S4 domain
AoKodu_16030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AoKodu_16040	COG0587	DNA-directed DNA polymerase activity
AoKodu_16050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AoKodu_16080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AoKodu_16090	COG3599	regulation of cell shape
AoKodu_16110	COG1799	cell septum assembly
AoKodu_16120	COG1496	oxidoreductase activity
AoKodu_16130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AoKodu_16150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AoKodu_16160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AoKodu_16180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AoKodu_16190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AoKodu_16200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AoKodu_16210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AoKodu_16220	COG0768	penicillin binding
AoKodu_16240	COG0275	rRNA processing
AoKodu_16250	COG2001	Belongs to the MraZ family
AoKodu_16270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AoKodu_16310	COG0318	PFAM AMP-dependent synthetase and ligase
AoKodu_16320	COG0318	PFAM AMP-dependent synthetase and ligase
AoKodu_16360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AoKodu_16370	COG0300	oxidoreductase activity
AoKodu_16380	COG0612	Peptidase, M16
AoKodu_16390	COG1185	polyribonucleotide nucleotidyltransferase activity
AoKodu_16400	COG1454	alcohol dehydrogenase
AoKodu_16420	COG0196	riboflavin kinase activity
AoKodu_16440	COG0577	efflux transmembrane transporter activity
AoKodu_16440	COG1136	(ABC) transporter
AoKodu_16460	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AoKodu_16470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AoKodu_16490	COG0330	HflC and HflK could
AoKodu_16520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AoKodu_16530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AoKodu_16600	COG0442	prolyl-tRNA aminoacylation
AoKodu_16670	COG0456	acetyltransferase
AoKodu_16680	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AoKodu_16690	COG0750	zinc metalloprotease
AoKodu_16700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AoKodu_16720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AoKodu_16740	COG0233	cytoplasmic translational termination
AoKodu_16760	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AoKodu_16770	COG0052	Belongs to the universal ribosomal protein uS2 family
AoKodu_16790	COG4974	Belongs to the 'phage' integrase family
AoKodu_16840	COG1716	ATPase activity
AoKodu_16880	COG0792	nuclease activity
AoKodu_16900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AoKodu_16910	COG0681	Belongs to the peptidase S26 family
AoKodu_16930	COG0681	Belongs to the peptidase S26 family
AoKodu_16940	COG0336	Belongs to the RNA methyltransferase TrmD family
AoKodu_16950	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AoKodu_16960	COG1837	Belongs to the UPF0109 family
AoKodu_17010	COG4585	Histidine kinase
AoKodu_17020	COG2197	response regulator
AoKodu_17040	COG1131	(ABC) transporter
AoKodu_17050	COG0842	Transport permease protein
AoKodu_17060	COG4585	Histidine kinase
AoKodu_17070	COG2197	response regulator
AoKodu_17100	COG1196	nuclear chromosome segregation
AoKodu_17110	COG4152	abc transporter atp-binding protein
AoKodu_17130	COG0105	UTP biosynthetic process
AoKodu_17140	COG1461	Dihydroxyacetone kinase
AoKodu_17150	COG0285	dihydrofolate synthase activity
AoKodu_17160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AoKodu_17230	COG1215	transferase activity, transferring glycosyl groups
AoKodu_17240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AoKodu_17250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AoKodu_17300	COG0656	L-ascorbic acid biosynthetic process
AoKodu_17320	COG4221	oxidoreductase activity
AoKodu_17330	COG2056	Na+-H+ antiporter family
AoKodu_17340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AoKodu_17350	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AoKodu_17360	COG0175	sulfate reduction
AoKodu_17390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AoKodu_17390	COG1648	precorrin-2 dehydrogenase activity
AoKodu_17400	COG0730	response to heat
AoKodu_17430	COG1132	(ABC) transporter
AoKodu_17430	COG2375	cellular response to nickel ion
AoKodu_17440	COG1122	ATPase activity
AoKodu_17470	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AoKodu_17490	COG4122	O-methyltransferase activity
AoKodu_17500	COG1222	aaa ATPase
AoKodu_17530	COG0454	-acetyltransferase
AoKodu_17540	COG1609	Transcriptional regulator
AoKodu_17550	COG0366	Alpha amylase catalytic
AoKodu_17610	COG0287	Prephenate dehydrogenase
AoKodu_17610	COG1605	Chorismate mutase
AoKodu_17620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AoKodu_17630	COG0740	serine-type endopeptidase activity
AoKodu_17680	COG0544	peptidyl-prolyl cis-trans isomerase activity
AoKodu_17700	COG1739	Uncharacterized protein family UPF0029
AoKodu_17730	COG1045	serine acetyltransferase
AoKodu_17770	COG3590	peptidase
AoKodu_17820	COG1263	PTS System
AoKodu_17830	COG2188	Transcriptional regulator
AoKodu_17840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AoKodu_17850	COG2190	(PTS) system
AoKodu_17870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AoKodu_17880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AoKodu_17940	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AoKodu_18080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AoKodu_18090	COG2326	polyphosphate kinase activity
AoKodu_18120	COG1615	UPF0182 protein
AoKodu_18160	COG3480	Lon protease (S16) C-terminal proteolytic domain
AoKodu_18200	COG1104	cysteine desulfurase activity
AoKodu_18230	COG0482	sulfurtransferase activity
AoKodu_18240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AoKodu_18280	COG0366	Alpha amylase catalytic
AoKodu_18320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AoKodu_18330	COG0058	SHG alpha-glucan phosphorylase activity
AoKodu_18410	COG0395	ABC-type sugar transport system, permease component
AoKodu_18420	COG1175	transmembrane transport
AoKodu_18440	COG0039	L-malate dehydrogenase activity
AoKodu_18460	COG1132	(ABC) transporter
AoKodu_18470	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AoKodu_18540	COG0045	succinate-CoA ligase (ADP-forming) activity
AoKodu_18570	COG0205	6-phosphofructokinase activity
AoKodu_18620	COG0366	Alpha amylase catalytic
AoKodu_18630	COG1501	Belongs to the glycosyl hydrolase 31 family
AoKodu_18640	COG0110	maltose O-acetyltransferase activity
AoKodu_18700	COG0604	alcohol dehydrogenase
AoKodu_18710	COG1846	Transcriptional regulator
AoKodu_18740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AoKodu_18750	COG0254	rRNA binding
AoKodu_18780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AoKodu_18790	COG0083	homoserine kinase activity
AoKodu_18800	COG0460	homoserine dehydrogenase
AoKodu_18840	COG0019	diaminopimelate decarboxylase activity
AoKodu_18850	COG0018	arginyl-trna synthetase
AoKodu_18870	COG0739	heme binding
AoKodu_18890	COG1253	flavin adenine dinucleotide binding
AoKodu_18940	COG0567	Dehydrogenase, E1 component
AoKodu_18940	COG0508	dehydrogenase complex catalyzes the overall conversion of
AoKodu_18980	COG1595	DNA-templated transcription, initiation
AoKodu_19000	COG2838	Isocitrate dehydrogenase
AoKodu_19030	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AoKodu_19040	COG1162	GTPase activity
AoKodu_19100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AoKodu_19120	COG0314	molybdopterin synthase activity
AoKodu_19140	COG0315	cyclic pyranopterin monophosphate synthase activity
AoKodu_19160	COG0315	cyclic pyranopterin monophosphate synthase activity
AoKodu_19160	COG0521	Mo-molybdopterin cofactor biosynthetic process
AoKodu_19190	COG1140	nitrate reductase beta subunit
AoKodu_19240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AoKodu_19330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AoKodu_19340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AoKodu_19360	COG1120	ATPase activity
AoKodu_19380	COG2249	NAD(P)H dehydrogenase (quinone) activity
AoKodu_19390	COG0456	acetyltransferase
AoKodu_19400	COG2249	NAD(P)H dehydrogenase (quinone) activity
AoKodu_19410	COG0483	inositol monophosphate 1-phosphatase activity
AoKodu_19430	COG1968	undecaprenyl-diphosphatase activity
AoKodu_19460	COG0420	3'-5' exonuclease activity
AoKodu_19470	COG0419	ATPase involved in DNA repair
AoKodu_19660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AoKodu_19670	COG0085	RNA polymerase activity
AoKodu_19700	COG0222	ribosome binding
AoKodu_19710	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AoKodu_19810	COG0653	protein targeting
AoKodu_19830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AoKodu_19840	COG5401	PFAM Sporulation and spore germination
AoKodu_19850	COG5000	phosphorelay sensor kinase activity
AoKodu_19850	COG5002	protein histidine kinase activity
AoKodu_19860	COG0745	RESPONSE REGULATOR receiver
AoKodu_19910	COG0714	Associated with various cellular activities
AoKodu_19920	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AoKodu_19960	COG2835	tetraacyldisaccharide 4'-kinase activity
AoKodu_20030	COG1482	cell wall glycoprotein biosynthetic process
AoKodu_20090	COG0438	transferase activity, transferring glycosyl groups
AoKodu_20110	COG0463	Glycosyl transferase, family 2
AoKodu_20110	COG1216	Glycosyl transferase, family 2
AoKodu_20200	COG0463	Glycosyl transferase, family 2
AoKodu_20290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AoKodu_20370	COG0673	inositol 2-dehydrogenase activity
AoKodu_20390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AoKodu_20440	COG1316	TRANSCRIPTIONal
AoKodu_20450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AoKodu_20530	COG0586	Pfam SNARE associated Golgi protein
AoKodu_20540	COG5002	protein histidine kinase activity
AoKodu_20550	COG0745	RESPONSE REGULATOR receiver
AoKodu_20580	COG0424	maF-like protein
AoKodu_20610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AoKodu_20620	COG1666	GTP binding
AoKodu_20630	COG2197	response regulator
AoKodu_20670	COG0501	Belongs to the peptidase M48B family
AoKodu_20710	COG2885	chlorophyll binding
AoKodu_20730	COG2801	Transposase and inactivated derivatives
AoKodu_20760	COG0142	geranyltranstransferase activity
AoKodu_20770	COG1007	ATP synthesis coupled electron transport
AoKodu_20790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AoKodu_20800	COG0713	ATP synthesis coupled electron transport
AoKodu_20820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AoKodu_20830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AoKodu_20840	COG1034	ATP synthesis coupled electron transport
AoKodu_20850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AoKodu_20870	COG0649	NAD binding
AoKodu_20880	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AoKodu_20890	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AoKodu_20910	COG0644	oxidoreductase
AoKodu_20920	COG2226	methyltransferase
AoKodu_20930	COG1169	isochorismate synthase
AoKodu_21080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AoKodu_21090	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AoKodu_21100	COG4948	Mandelate Racemase Muconate Lactonizing
AoKodu_21140	COG4176	ABC-type proline glycine betaine transport system permease component
AoKodu_21170	COG1940	carbohydrate kinase activity
AoKodu_21180	COG5426	von Willebrand factor, type A
AoKodu_21200	COG1175	transmembrane transport
AoKodu_21210	COG0395	ABC-type sugar transport system, permease component
AoKodu_21220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AoKodu_21230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AoKodu_21240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AoKodu_21250	COG2235	arginine
AoKodu_21280	COG2197	response regulator
AoKodu_21290	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AoKodu_21360	COG1397	ADP-ribosylglycohydrolase
AoKodu_21370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AoKodu_21410	COG0406	alpha-ribazole phosphatase activity
AoKodu_21430	COG2171	N-acyltransferase activity
AoKodu_21450	COG1053	succinate dehydrogenase
AoKodu_21590	COG1217	gtp-binding protein TYPA
AoKodu_21660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AoKodu_21670	COG0601	transmembrane transport
AoKodu_21690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AoKodu_21710	COG2267	carboxylic ester hydrolase activity
AoKodu_21740	COG1902	pentaerythritol trinitrate reductase activity
AoKodu_21750	COG1733	regulation of RNA biosynthetic process
AoKodu_21760	COG0604	alcohol dehydrogenase
AoKodu_21770	COG3012	SEC-C Motif Domain Protein
AoKodu_21780	COG1362	aminopeptidase activity
AoKodu_21790	COG0546	phosphoglycolate phosphatase activity
AoKodu_21900	COG0698	ribose 5-phosphate isomerase
AoKodu_21920	COG0698	ribose 5-phosphate isomerase
AoKodu_21930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AoKodu_21970	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AoKodu_21990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AoKodu_21990	COG0574	Belongs to the PEP-utilizing enzyme family
AoKodu_22010	COG2211	Major facilitator Superfamily
AoKodu_22030	COG0438	transferase activity, transferring glycosyl groups
AoKodu_22030	COG0297	glycogen (starch) synthase activity
AoKodu_22270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AoKodu_22310	COG1490	D-aminoacyl-tRNA deacylase activity
AoKodu_22330	COG0354	folic acid binding
AoKodu_22340	COG3485	protocatechuate 3,4-dioxygenase
AoKodu_22360	COG0745	RESPONSE REGULATOR receiver
AoKodu_22370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AoKodu_22400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AoKodu_22410	COG0494	nUDIX hydrolase
AoKodu_22410	COG0406	alpha-ribazole phosphatase activity
AoKodu_22420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AoKodu_22460	COG0513	Belongs to the DEAD box helicase family
AoKodu_22480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AoKodu_22500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AoKodu_22510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AoKodu_22560	COG0431	NADPH-dependent FMN reductase
AoKodu_22570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AoKodu_22610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AoKodu_22630	COG1124	(ABC) transporter
AoKodu_22640	COG0444	Belongs to the ABC transporter superfamily
AoKodu_22700	COG4585	Histidine kinase
AoKodu_22710	COG2197	response regulator
AoKodu_22720	COG0193	aminoacyl-tRNA hydrolase activity
AoKodu_22730	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AoKodu_22790	COG0148	phosphopyruvate hydratase activity
AoKodu_22830	COG1136	(ABC) transporter
AoKodu_22890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AoKodu_22910	COG1309	transcriptional regulator
AoKodu_23080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AoKodu_23090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AoKodu_23090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AoKodu_23110	COG0714	Associated with various cellular activities
AoKodu_23200	COG0488	(ABC) transporter
AoKodu_23210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AoKodu_23220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AoKodu_23250	COG0084	hydrolase, TatD family'
AoKodu_23260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AoKodu_23280	COG1335	isochorismatase
AoKodu_23320	COG0697	spore germination
AoKodu_23360	COG1297	OPT oligopeptide transporter protein
AoKodu_23370	COG2814	Major facilitator Superfamily
AoKodu_23380	COG0640	Transcriptional regulator
AoKodu_23390	COG1215	transferase activity, transferring glycosyl groups
AoKodu_23650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AoKodu_23670	COG1970	mechanosensitive ion channel activity
AoKodu_23710	COG0791	NLP P60 protein
AoKodu_23710	COG1388	LysM domain
AoKodu_23710	COG3103	Sh3 type 3 domain protein
AoKodu_23760	COG2252	PERMEase
AoKodu_23770	COG1201	RNA secondary structure unwinding
AoKodu_23810	COG0789	Transcriptional regulator
AoKodu_23860	COG1061	Type III restriction enzyme res subunit
AoKodu_23950	COG1842	Phage shock protein A
AoKodu_23970	COG0745	RESPONSE REGULATOR receiver
AoKodu_23980	COG2205	protein histidine kinase activity
AoKodu_24010	COG0459	protein refolding
AoKodu_24040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AoKodu_24060	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AoKodu_24070	COG0215	cysteine-tRNA ligase activity
AoKodu_24080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AoKodu_24130	COG3842	ATPase activity
AoKodu_24240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AoKodu_24290	COG0561	phosphatase activity
AoKodu_24330	COG3716	PTS system mannose fructose sorbose family IID component
AoKodu_24340	COG3715	PTS system
AoKodu_24350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AoKodu_24350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AoKodu_24360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AoKodu_24390	COG1621	beta-fructofuranosidase activity
AoKodu_24400	COG1609	Transcriptional regulator
AoKodu_24410	COG0546	phosphoglycolate phosphatase activity
AoKodu_24460	COG0542	response to heat
AoKodu_24500	COG3655	Transcriptional regulator
AoKodu_24530	COG1136	(ABC) transporter
AoKodu_24530	COG0577	efflux transmembrane transporter activity
AoKodu_24570	COG0745	RESPONSE REGULATOR receiver
AoKodu_24580	COG2205	protein histidine kinase activity
AoKodu_24630	COG0789	Transcriptional regulator
AoKodu_24640	COG0484	heat shock protein binding
AoKodu_24650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AoKodu_24660	COG0443	Heat shock 70 kDa protein
AoKodu_24710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AoKodu_24730	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AoKodu_24740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AoKodu_24820	COG2197	response regulator
AoKodu_24830	COG4585	Histidine kinase
AoKodu_24950	COG0778	Nitroreductase
AoKodu_24960	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
AoKodu_25150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AoKodu_25350	COG0601	transmembrane transport
AoKodu_25360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AoKodu_25370	COG3842	ATPase activity
AoKodu_25410	COG1733	regulation of RNA biosynthetic process
AoKodu_25470	COG0247	lactate metabolic process
AoKodu_25470	COG2181	nitrate reductase activity
AoKodu_25480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AoKodu_25500	COG2197	response regulator
AoKodu_25510	COG4585	Histidine kinase
AoKodu_25660	COG1131	(ABC) transporter
AoKodu_25720	COG2197	response regulator
AoKodu_25760	COG2801	Transposase and inactivated derivatives
AoKodu_25760	COG3415	Transposase
AoKodu_25780	COG0483	inositol monophosphate 1-phosphatase activity
AoKodu_25790	COG1113	amino acid transport
AoKodu_25810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AoKodu_25820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AoKodu_25830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AoKodu_25830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AoKodu_25840	COG1940	carbohydrate kinase activity
AoKodu_25850	COG0628	permease
AoKodu_25870	COG1854	S-ribosylhomocysteine lyase activity
AoKodu_25900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AoKodu_25920	COG1733	regulation of RNA biosynthetic process
AoKodu_25950	COG0789	Transcriptional regulator
AoKodu_25960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AoKodu_25970	COG2985	domain, Protein
AoKodu_25970	COG0569	domain protein
AoKodu_25980	COG1966	Carbon starvation protein
AoKodu_26010	COG1716	ATPase activity
AoKodu_26020	COG1716	ATPase activity
AoKodu_26050	COG0768	penicillin binding
AoKodu_26060	COG0515	serine threonine protein kinase
AoKodu_26070	COG0515	serine threonine protein kinase
AoKodu_26070	COG2815	serine threonine protein kinase
AoKodu_26080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AoKodu_26090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AoKodu_26170	COG3345	alpha-galactosidase
AoKodu_26190	COG0673	inositol 2-dehydrogenase activity
AoKodu_26200	COG0617	tRNA 3'-terminal CCA addition
AoKodu_26240	COG0492	ferredoxin-NADP+ reductase activity
AoKodu_26250	COG3118	belongs to the thioredoxin family
AoKodu_26270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AoKodu_26280	COG1181	Belongs to the D-alanine--D-alanine ligase family
AoKodu_26310	COG0357	Ribosomal RNA small subunit methyltransferase G
AoKodu_26330	COG0706	membrane insertase activity
AoKodu_26340	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AoKodu_26350	COG0594	ribonuclease P activity
AoKodu_26360	COG0230	Belongs to the bacterial ribosomal protein bL34 family