locus-tag	class	description
AXE84_00010	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AXE84_00020	ENOG4105E98	transcriptional regulator DeoR family
AXE84_00025	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AXE84_00030	ENOG4107T8Q	Glycosyl transferase (Group 1
AXE84_00035	ENOG4107QPH	glycogen) synthase
AXE84_00040	ENOG4105BZ1	(ABC) transporter
AXE84_00055	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AXE84_00060	ENOG4105EB3	Histidine kinase
AXE84_00065	ENOG4105ETX	regulatoR
AXE84_00075	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AXE84_00080	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AXE84_00085	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXE84_00090	ENOG4105K46	50S ribosomal protein l27
AXE84_00095	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AXE84_00100	ENOG4105C03	ribonuclease
AXE84_00105	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AXE84_00110	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AXE84_00115	ENOG4108JJ9	ABC, transporter
AXE84_00120	ENOG4108JJ8	(ABC) transporter
AXE84_00135	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AXE84_00140	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AXE84_00155	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AXE84_00160	ENOG4105ETE	Transcriptional regulator (LacI family
AXE84_00165	ENOG4105EDR	glucose galactose transporter
AXE84_00170	ENOG4105NWF	RbsD or FucU transport
AXE84_00175	ENOG4105DET	Rhamnulokinase
AXE84_00185	ENOG4107W7X	Aldolase
AXE84_00200	ENOG4105DP4	dak2 domain fusion protein ylov
AXE84_00205	ENOG4105VB9	50S ribosomal protein l28
AXE84_00215	ENOG4105CPF	Cell wall formation (By similarity)
AXE84_00220	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AXE84_00230	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AXE84_00235	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AXE84_00255	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AXE84_00265	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AXE84_00280	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AXE84_00290	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AXE84_00300	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AXE84_00305	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AXE84_00310	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AXE84_00335	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AXE84_00340	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXE84_00350	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AXE84_00360	ENOG4105CKU	formyltetrahydrofolate synthetase
AXE84_00365	ENOG4105KC9	Modulates RecA activity (By similarity)
AXE84_00370	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AXE84_00380	ENOG4105WBV	Transcriptional regulator
AXE84_00385	ENOG4105CEV	competence damage-inducible protein
AXE84_00395	ENOG4105PNM	synthesis protein
AXE84_00400	ENOG4107QZI	cell division protein FtsK
AXE84_00405	ENOG4107UH8	sugar kinase
AXE84_00410	ENOG4105CN5	Metallo-Beta-Lactamase
AXE84_00415	ENOG4108ZJ4	polysaccharide deacetylase
AXE84_00450	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AXE84_00460	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AXE84_00480	ENOG4105BZG	amino acid carrier protein
AXE84_00505	ENOG4108J5H	Homocysteine s-methyltransferase
AXE84_00510	ENOG4108IQI	permease
AXE84_00515	ENOG410901E	Membrane
AXE84_00565	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AXE84_00570	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AXE84_00590	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AXE84_00600	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AXE84_00620	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AXE84_00635	ENOG4108426	dNA-binding protein
AXE84_00640	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AXE84_00645	ENOG4105DKQ	ROK family
AXE84_00650	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AXE84_00655	ENOG4108JQ7	(ABC) transporter
AXE84_00670	ENOG4105DEF	Extracellular solute-binding protein, family 5
AXE84_00695	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AXE84_00705	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
AXE84_00710	ENOG4105CAK	Cell division ATP-binding protein ftsE
AXE84_00725	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AXE84_00730	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AXE84_00755	ENOG4105IDI	abc transporter atp-binding protein
AXE84_00760	ENOG4108UGD	Serine Threonine protein kinase
AXE84_00765	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AXE84_00780	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
AXE84_00790	ENOG4105ESV	Glycosyl transferase, family 4
AXE84_00810	ENOG4105EY8	ABC transporter
AXE84_00820	ENOG4105K64	Glycosyl transferase, family 2
AXE84_00840	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
AXE84_00845	ENOG4107SJB	teichoic acid biosynthesis
AXE84_00855	ENOG4108KGH	TRANSCRIPTIONal
AXE84_00860	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AXE84_00875	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AXE84_00880	ENOG4108IG5	Transcriptional regulator
AXE84_00890	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AXE84_00905	ENOG4105D0C	transport protein
AXE84_00910	ENOG4105DWK	Membrane
AXE84_00940	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AXE84_00945	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AXE84_00950	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AXE84_00965	ENOG4105EC2	ftsk spoIIIe
AXE84_00995	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AXE84_01005	ENOG4105KVH	Transcriptional regulator
AXE84_01025	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
AXE84_01035	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
AXE84_01040	ENOG4105E98	transcriptional regulator DeoR family
AXE84_01050	ENOG4105C9Q	fumarate hydratase class II
AXE84_01095	ENOG4105C1J	atp-dependent rna helicase
AXE84_01100	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AXE84_01125	ENOG4105PGM	cation diffusion facilitator family transporter
AXE84_01130	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
AXE84_01140	ENOG4105CJW	magnesium transporter
AXE84_01155	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AXE84_01160	ENOG4107ZBN	O-methyltransferase
AXE84_01165	ENOG4108URH	decarboxylase
AXE84_01170	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AXE84_01175	ENOG4107RPQ	ABC transporter
AXE84_01190	ENOG4107SIG	periplasmic solute binding protein
AXE84_01225	ENOG4105UIB	(ABC) transporter
AXE84_01230	ENOG4108JQ9	ABC transporter
AXE84_01235	ENOG4105DIH	basic membrane
AXE84_01240	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AXE84_01255	ENOG4105E98	transcriptional regulator DeoR family
AXE84_01260	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AXE84_01270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_01275	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_01285	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AXE84_01300	ENOG4105EDQ	levansucrase EC 2.4.1.10
AXE84_01305	ENOG4108HKT	sucrose-6-phosphate hydrolase
AXE84_01310	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AXE84_01315	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AXE84_01325	ENOG4105KDC	50s ribosomal protein l28
AXE84_01330	ENOG4105W0E	50S ribosomal protein L33
AXE84_01335	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AXE84_01340	ENOG4105NRA	50s ribosomal protein l31 type b
AXE84_01345	ENOG4108638	50S ribosomal protein L36
AXE84_01355	ENOG4106032	Glutathionylspermidine synthase
AXE84_01370	ENOG4108638	50S ribosomal protein L36
AXE84_01380	ENOG4105KI2	Urea amidohydrolase subunit beta
AXE84_01385	ENOG4105CQM	Urea amidohydrolase subunit alpha
AXE84_01395	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AXE84_01400	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AXE84_01435	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
AXE84_01445	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AXE84_01450	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AXE84_01455	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AXE84_01460	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AXE84_01465	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AXE84_01470	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AXE84_01475	ENOG4105ZA1	atp synthase
AXE84_01480	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
AXE84_01490	ENOG4105ESV	Glycosyl transferase, family 4
AXE84_01500	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_01505	ENOG4108FKE	two-component system sensor kinase
AXE84_01525	ENOG4107S0N	DJ-1 family
AXE84_01535	ENOG4107SQC	5-methylcytosine-specific restriction enzyme subunit McrC
AXE84_01540	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AXE84_01550	ENOG41086VY	Fic/DOC family
AXE84_01560	ENOG4105E5G	Alpha beta hydrolase fold
AXE84_01595	ENOG4105BZU	Histidine kinase
AXE84_01600	ENOG4105CJ1	ABC, transporter
AXE84_01615	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AXE84_01635	ENOG4107QNK	)-transporter
AXE84_01640	ENOG4105C26	Dehydrogenase
AXE84_01645	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
AXE84_01650	ENOG4105DH8	myo-inositol catabolism
AXE84_01665	ENOG4105FDP	GntR family transcriptional regulator
AXE84_01670	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AXE84_01680	ENOG4107WI4	Aldose-1-epimerase
AXE84_01685	ENOG4105ETE	Transcriptional regulator (LacI family
AXE84_01695	ENOG4107QNK	)-transporter
AXE84_01700	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
AXE84_01730	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AXE84_01750	ENOG4105BZU	Histidine kinase
AXE84_01755	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_01810	ENOG4105CSC	Glucose uptake protein
AXE84_01815	ENOG410849S	phosphocarrier protein (HPr)
AXE84_01830	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AXE84_01835	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AXE84_01840	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AXE84_01845	ENOG4108UB4	uncharacterized protein ygjQ
AXE84_01855	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
AXE84_01875	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AXE84_01885	ENOG4105E33	succinate dehydrogenase
AXE84_01915	ENOG4108097	ATP-binding protein
AXE84_01920	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AXE84_01940	ENOG4105CS9	pantothenic acid kinase
AXE84_01975	ENOG4108UJD	30S ribosomal protein S9
AXE84_01980	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AXE84_01985	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AXE84_01995	ENOG4105KT7	mgtC SapB transporter
AXE84_02005	ENOG4108ZT0	50S ribosomal protein l17
AXE84_02010	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXE84_02015	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AXE84_02020	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXE84_02025	ENOG41067V7	50S ribosomal protein L36
AXE84_02030	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AXE84_02035	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AXE84_02040	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AXE84_02045	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AXE84_02050	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AXE84_02055	ENOG410849U	50S ribosomal protein L30
AXE84_02060	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AXE84_02065	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AXE84_02070	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AXE84_02075	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AXE84_02080	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AXE84_02085	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXE84_02090	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AXE84_02095	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AXE84_02100	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AXE84_02105	ENOG41082SA	50s ribosomal protein l29
AXE84_02110	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AXE84_02115	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AXE84_02120	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AXE84_02125	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AXE84_02130	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXE84_02135	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AXE84_02145	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AXE84_02150	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AXE84_02170	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AXE84_02175	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AXE84_02180	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AXE84_02185	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AXE84_02210	ENOG4107U53	septum site-determining protein minD
AXE84_02230	ENOG4105CDV	Ompa motb domain protein
AXE84_02255	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AXE84_02265	ENOG4105CDV	Ompa motb domain protein
AXE84_02270	ENOG4105CDV	Ompa motb domain protein
AXE84_02275	ENOG4105CDV	Ompa motb domain protein
AXE84_02280	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AXE84_02285	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AXE84_02290	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AXE84_02330	ENOG4107R4N	Cell wall formation (By similarity)
AXE84_02340	ENOG4105CZN	Potassium uptake protein
AXE84_02360	ENOG4105VDH	Dihydroxyacetone kinase
AXE84_02365	ENOG4108UTZ	Dihydroxyacetone kinase
AXE84_02370	ENOG4105CMT	Dihydroxyacetone kinase
AXE84_02395	ENOG4105C54	Major Facilitator superfamily
AXE84_02405	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AXE84_02410	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
AXE84_02445	ENOG4105DKT	Transcriptional regulator
AXE84_02450	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AXE84_02455	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AXE84_02460	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AXE84_02465	ENOG4105C59	p-type ATPase
AXE84_02480	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AXE84_02485	ENOG4107QR9	Iron-sulfur cluster binding protein
AXE84_02490	ENOG41080R8	Conserved Protein
AXE84_02495	ENOG4105DEI	Mannitol dehydrogenase
AXE84_02505	ENOG4105DUX	Transporter
AXE84_02510	ENOG4105DUX	Transporter
AXE84_02540	ENOG4105C26	Dehydrogenase
AXE84_02555	ENOG4105D82	Glutamate dehydrogenase
AXE84_02565	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
AXE84_02570	ENOG4105E0A	ABC, transporter
AXE84_02575	ENOG4105TVJ	transport system, permease
AXE84_02580	ENOG4105DQ5	transport system permease protein
AXE84_02590	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AXE84_02605	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AXE84_02625	ENOG4105CRK	lysyL-tRNA synthetase
AXE84_02635	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AXE84_02640	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AXE84_02670	ENOG4105EEI	dihydropteroate synthase
AXE84_02675	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_02680	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_02685	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_02690	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_02705	ENOG410814C	multidrug resistance protein
AXE84_02710	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
AXE84_02725	ENOG4105EUJ	GTP cyclohydrolase i
AXE84_02730	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AXE84_02770	ENOG4108KQ5	Integrase catalytic subunit
AXE84_02780	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AXE84_02795	ENOG4105F0N	pyrophosphate phospho-hydrolase
AXE84_02810	ENOG4108IQK	o-acetylhomoserine
AXE84_02815	ENOG4105DWV	Homoserine O-trans-acetylase
AXE84_02825	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AXE84_02835	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AXE84_02855	ENOG4105C3G	gtp-binding protein
AXE84_02870	ENOG4105Y3U	Transglycosylase-associated protein
AXE84_02895	ENOG4105EMN	RNA polymerase sigma factor
AXE84_02910	ENOG4108IQI	permease
AXE84_02915	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AXE84_02920	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AXE84_02925	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AXE84_02930	ENOG4105D7K	pfkb domain protein
AXE84_02945	ENOG4105E0X	reductase
AXE84_02985	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AXE84_03010	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_03015	ENOG4107RBB	ABC transporter, permease
AXE84_03020	ENOG4105BZ1	(ABC) transporter
AXE84_03025	ENOG4105BZ1	(ABC) transporter
AXE84_03050	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AXE84_03055	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AXE84_03070	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AXE84_03080	ENOG4105DM4	PTS System
AXE84_03090	ENOG4105E98	transcriptional regulator DeoR family
AXE84_03100	ENOG4105D82	Glutamate dehydrogenase
AXE84_03110	ENOG4105ECP	epimerase
AXE84_03120	ENOG4105VE1	Phosphatidylcholine synthase
AXE84_03140	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AXE84_03155	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AXE84_03175	ENOG4105C8V	SAICAR synthetase
AXE84_03180	ENOG4105C12	Phosphoribosylglycinamide synthetase
AXE84_03210	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AXE84_03250	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AXE84_03280	ENOG4107RCW	fructose-bisphosphate aldolase
AXE84_03290	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AXE84_03295	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AXE84_03300	ENOG4105DTD	Dehydrogenase
AXE84_03325	ENOG4105DHP	deoxycytidine triphosphate deaminase
AXE84_03390	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXE84_03425	ENOG4108VJY	integral membrane protein
AXE84_03445	ENOG4107ZT3	family UPF0126
AXE84_03455	ENOG4106N3A	copper homeostasis protein cutc
AXE84_03475	ENOG4105CQ7	ATP-dependent helicase
AXE84_03480	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AXE84_03510	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AXE84_03520	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXE84_03525	ENOG4105BZU	Histidine kinase
AXE84_03535	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AXE84_03555	ENOG4105HDK	L-asparaginase
AXE84_03585	ENOG4107QRG	dna polymerase iii
AXE84_03590	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AXE84_03615	ENOG4105FDP	GntR family transcriptional regulator
AXE84_03630	ENOG4105GR3	Histidine kinase
AXE84_03635	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AXE84_03650	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AXE84_03665	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXE84_03670	ENOG4105BZU	Histidine kinase
AXE84_03695	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AXE84_03705	ENOG4105D3R	alkyl hydroperoxide reductase
AXE84_03755	ENOG4108UMN	azlc family
AXE84_03770	ENOG4105D74	hydrolase
AXE84_03780	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_03805	ENOG4108JQC	penicillin-binding protein 1A
AXE84_03810	ENOG4105DIN	metallophosphoesterase
AXE84_03815	ENOG4108PSK	reductase
AXE84_03835	ENOG4107TE5	Lipid kinase
AXE84_03855	ENOG4105CE1	Ferrous iron transport protein b
AXE84_03860	ENOG4105CE1	Ferrous iron transport protein b
AXE84_03870	ENOG4105CE1	Ferrous iron transport protein b
AXE84_03875	ENOG4105CE1	Ferrous iron transport protein b
AXE84_03895	ENOG4105UEI	Transcriptional Regulator AraC Family
AXE84_03940	ENOG4107JTW	chlorite dismutase
AXE84_03945	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AXE84_03950	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AXE84_03955	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AXE84_03965	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AXE84_03975	ENOG4105D52	delta-aminolevulinic acid dehydratase
AXE84_03980	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AXE84_03990	ENOG41080RH	Thioredoxin
AXE84_04000	ENOG4107R3N	Filamentation induced by cAMP protein fic
AXE84_04020	ENOG4105EYW	Ion transport protein
AXE84_04035	ENOG4105CFH	Aspartokinase
AXE84_04040	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AXE84_04075	ENOG4105U5Y	Transcriptional regulator
AXE84_04095	ENOG4105C2W	permease
AXE84_04155	ENOG4105CQ7	ATP-dependent helicase
AXE84_04165	ENOG4108Z6B	deaminase
AXE84_04170	ENOG4105C94	Transporter
AXE84_04175	ENOG4105CV8	reductase
AXE84_04180	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AXE84_04215	ENOG4105BZU	Histidine kinase
AXE84_04225	ENOG4105VT3	DNA binding domain protein, excisionase family
AXE84_04235	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_04240	ENOG4105D01	(LipO)protein
AXE84_04245	ENOG4108UMI	ABC transporter, permease
AXE84_04250	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AXE84_04260	ENOG4105KJF	protein tyrosine phosphatase
AXE84_04285	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AXE84_04350	ENOG4105KME	endoribonuclease L-psp
AXE84_04380	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AXE84_04385	ENOG41082T9	Membrane
AXE84_04400	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AXE84_04435	ENOG4107QTF	adenylosuccinate lyase
AXE84_04490	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_04500	ENOG4105VPX	protein, conserved in bacteria
AXE84_04555	ENOG4105C87	Aminotransferase class I and II
AXE84_04560	ENOG4105C28	cystathionine
AXE84_04620	ENOG4107QKS	N-acylglucosamine 2-epimerase
AXE84_04625	ENOG4105EPJ	extracellular solute-binding protein family 1
AXE84_04630	ENOG410667J	hydrolase
AXE84_04635	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AXE84_04640	ENOG4105C5Q	Transcriptional regulator
AXE84_04665	ENOG4105DBE	peroxidase
AXE84_04670	ENOG410650H	(LipO)protein
AXE84_04700	ENOG4106AX4	
AXE84_04750	ENOG4105C09	Bile acid
AXE84_04760	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AXE84_04765	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AXE84_04815	ENOG4105EJQ	L-serine dehydratase
AXE84_04820	ENOG4107QW3	Sucrose phosphorylase
AXE84_04825	ENOG4105KVH	Transcriptional regulator
AXE84_04840	ENOG4105DWF	phosphomethylpyrimidine kinase
AXE84_04850	ENOG4105FDK	ABC transporter
AXE84_04860	ENOG4105CDU	Replicative dna helicase
AXE84_04870	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AXE84_04875	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AXE84_04885	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
AXE84_04890	ENOG4105BZ4	penicillin-binding protein
AXE84_04895	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AXE84_04905	ENOG4108U4N	(sortase) family
AXE84_04915	ENOG4107U91	Rhomboid family
AXE84_04950	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AXE84_04960	ENOG4105VZ8	Transcriptional regulator
AXE84_04990	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXE84_04995	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXE84_05000	ENOG4105K7N	UPF0232 protein
AXE84_05005	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AXE84_05010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AXE84_05015	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AXE84_05020	ENOG41084CH	50S ribosomal protein l34
AXE84_05030	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AXE84_05035	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AXE84_05045	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AXE84_05050	ENOG4107QJE	Chromosome Partitioning Protein
AXE84_05060	ENOG4105CPF	Cell wall formation (By similarity)
AXE84_05065	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXE84_05075	ENOG4105K63	Thioredoxin
AXE84_05080	ENOG4105C3M	thioredoxin reductase
AXE84_05095	ENOG41062IR	nudix hydrolase
AXE84_05100	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AXE84_05105	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AXE84_05110	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
AXE84_05155	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AXE84_05160	ENOG4108JQ1	Dehydrogenase
AXE84_05165	ENOG4107R3N	Filamentation induced by cAMP protein fic
AXE84_05170	ENOG4105D9P	serine threonine protein kinase
AXE84_05175	ENOG4107TPY	serine threonine protein kinase
AXE84_05180	ENOG4105CJN	penicillin-binding protein
AXE84_05195	ENOG4105HZM	Fha domain containing protein
AXE84_05200	ENOG4105TV9	FHA Domain-Containing protein
AXE84_05220	ENOG4105D22	carbon starvation protein
AXE84_05225	ENOG4107WGA	YidE YbjL
AXE84_05245	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AXE84_05255	ENOG4105DSF	transport protein
AXE84_05260	ENOG4105DKQ	ROK family
AXE84_05265	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AXE84_05270	ENOG41083TI	Protein CrcB homolog
AXE84_05275	ENOG41083YR	Protein CrcB homolog
AXE84_05285	ENOG4105C85	amino acid
AXE84_05290	ENOG4105ECY	inositol monophosphatase
AXE84_05305	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_05400	ENOG4105BZU	Histidine kinase
AXE84_05405	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_05415	ENOG4105D1H	recombination factor protein RarA
AXE84_05420	ENOG4105DF6	Fe-S oxidoreductase
AXE84_05460	ENOG4108UCS	ABC, transporter
AXE84_05520	ENOG4105C0D	helicase
AXE84_05605	ENOG4105YXB	Toxic component of a toxin-antitoxin (TA) module. A
AXE84_05610	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AXE84_05655	ENOG4105BZU	Histidine kinase
AXE84_05660	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_05665	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AXE84_05705	ENOG4105EHG	Permease protein
AXE84_05710	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AXE84_05720	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AXE84_05740	ENOG4105CFG	Acts as a chaperone (By similarity)
AXE84_05745	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXE84_05750	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AXE84_05755	ENOG4105KNI	merR family transcriptional Regulator
AXE84_05780	ENOG4106F60	Histidine kinase
AXE84_05805	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_05820	ENOG4105VMP	Transcriptional regulator
AXE84_05840	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AXE84_05865	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AXE84_05870	ENOG4105ETE	Transcriptional regulator (LacI family
AXE84_05875	ENOG4108HKT	sucrose-6-phosphate hydrolase
AXE84_05890	ENOG4105YHU	PTS system
AXE84_05895	ENOG4108EQA	pts system
AXE84_05900	ENOG4105ETZ	PTS System
AXE84_05905	ENOG4105F3R	pts system mannose fructose sorbose family iid
AXE84_05925	ENOG4105J7I	hydrolase
AXE84_05950	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AXE84_06005	ENOG4105C8N	cysteinyl-tRNA synthetase
AXE84_06010	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AXE84_06025	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AXE84_06040	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AXE84_06055	ENOG4105BZU	Histidine kinase
AXE84_06060	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXE84_06080	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AXE84_06085	ENOG4105CFI	type iii restriction protein res subunit
AXE84_06110	ENOG4107QRT	dEAD DEAH box helicase
AXE84_06115	ENOG4105C7N	Xanthine uracil vitamin C permease
AXE84_06195	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AXE84_06200	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
AXE84_06235	ENOG4105YVS	arsR family transcriptional regulator
AXE84_06240	ENOG4107XZQ	multidrug resistance protein
AXE84_06245	ENOG4105EPD	Oligopeptide transporter, Opt family
AXE84_06275	ENOG4108KTG	Membrane protein, drug metabolite transporter
AXE84_06295	ENOG4108RWI	nicotinamidase
AXE84_06305	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AXE84_06310	ENOG4105F8V	Hydrolase, tatD family
AXE84_06325	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AXE84_06330	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AXE84_06335	ENOG4105C5H	ABC transporter
AXE84_06375	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXE84_06385	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AXE84_06470	ENOG41067SE	Tetr family transcriptional regulator
AXE84_06485	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXE84_06490	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AXE84_06515	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AXE84_06535	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AXE84_06555	ENOG4105FF2	Type I DHQase
AXE84_06570	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AXE84_06575	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AXE84_06580	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_06585	ENOG4105BZU	Histidine kinase
AXE84_06610	ENOG4105C01	Dihydroxy-acid dehydratase
AXE84_06620	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
AXE84_06630	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXE84_06650	ENOG4105C7B	Threonine dehydratase
AXE84_06655	ENOG4108YYH	Nadph-dependent fmn reductase
AXE84_06675	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AXE84_06680	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AXE84_06690	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AXE84_06695	ENOG4105C1J	atp-dependent rna helicase
AXE84_06715	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AXE84_06725	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AXE84_06740	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AXE84_06745	ENOG4107NHD	transcriptional regulator
AXE84_06755	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
AXE84_06760	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AXE84_06770	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AXE84_06880	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AXE84_06890	ENOG4107RA4	Glycosyl transferase (Group 1
AXE84_06910	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AXE84_06920	ENOG4105FF5	Membrane
AXE84_06940	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AXE84_06950	ENOG4107YVI	ribose 5-phosphate isomerase
AXE84_06960	ENOG4107YVI	ribose 5-phosphate isomerase
AXE84_07055	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AXE84_07060	ENOG4105DFM	M18 family aminopeptidase
AXE84_07065	ENOG4105K5B	UPF0225 protein
AXE84_07070	ENOG4105CIS	alcohol dehydrogenase
AXE84_07080	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AXE84_07095	ENOG4105E5G	Alpha beta hydrolase fold
AXE84_07105	ENOG4105DEN	Luciferase family
AXE84_07115	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AXE84_07120	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXE84_07160	ENOG4105CI3	gtp-binding protein typa
AXE84_07170	ENOG4108Z4U	Ferredoxin
AXE84_07225	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AXE84_07230	ENOG4108RH7	phosphoglycerate mutase
AXE84_07255	ENOG4108KD5	ADP-ribosylation crystallin J1
AXE84_07280	ENOG4105K6V	RNA polymerase
AXE84_07285	ENOG4105RNG	membrane
AXE84_07290	ENOG4107SIQ	Naphthoate synthase
AXE84_07295	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_07310	ENOG4105CEU	Arginine dihydrolase
AXE84_07315	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AXE84_07320	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXE84_07325	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AXE84_07330	ENOG4105I1K	ABC transporter
AXE84_07345	ENOG4105CT8	Phosphorylase
AXE84_07350	ENOG4105E2R	ROK family
AXE84_07365	ENOG4108HQS	Glycine betaine
AXE84_07385	ENOG4107TCW	O-succinylbenzoate synthase
AXE84_07390	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AXE84_07395	ENOG4105C0H	protease
AXE84_07400	ENOG4105E4F	Isochorismate synthase
AXE84_07405	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AXE84_07410	ENOG4105P52	geranylgeranyl reductase
AXE84_07420	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXE84_07425	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXE84_07430	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXE84_07440	ENOG4107QIZ	NADH dehydrogenase
AXE84_07445	ENOG4108IEH	NADH dehydrogenase subunit g
AXE84_07450	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AXE84_07455	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXE84_07465	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXE84_07470	ENOG4105D65	subunit l
AXE84_07480	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXE84_07495	ENOG4107QKZ	Ompa motb domain protein
AXE84_07500	ENOG4107QKZ	Ompa motb domain protein
AXE84_07520	ENOG4105D0M	Protease HtpX homolog
AXE84_07540	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_07545	ENOG4108VPT	UPF0234 protein
AXE84_07565	ENOG4105WDJ	50S ribosomal protein L33
AXE84_07580	ENOG4107WR6	Maf-like protein
AXE84_07595	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXE84_07600	ENOG4105BZU	Histidine kinase
AXE84_07640	ENOG4105CMR	udp-glucose 4-epimerase
AXE84_07645	ENOG4108KGH	TRANSCRIPTIONal
AXE84_07670	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXE84_07680	ENOG4105CK5	oxidoreductase
AXE84_07800	ENOG4105EY8	ABC transporter
AXE84_07805	ENOG4105K64	Glycosyl transferase, family 2
AXE84_07815	ENOG4105CG5	Glycosyl transferase (Group 1
AXE84_07845	ENOG4105EIP	mannose-6-phosphate isomerase
AXE84_07855	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AXE84_07880	ENOG4105W49	UPF0434 protein
AXE84_07900	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXE84_07905	ENOG4108WQ6	secreted protein
AXE84_07920	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXE84_07925	ENOG4105BZU	Histidine kinase
AXE84_07930	ENOG4108T3R	lipoprotein lpqB
AXE84_07935	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
AXE84_07945	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AXE84_07985	ENOG4108VZM	50s ribosomal protein L10
AXE84_07990	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AXE84_08000	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXE84_08005	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXE84_08090	ENOG4105EYH	Exonuclease
AXE84_08095	ENOG4107RH8	nuclease SbcCD subunit D
AXE84_08110	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AXE84_08120	ENOG4107TK4	histidinol-phosphate phosphatase
AXE84_08125	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AXE84_08130	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AXE84_08150	ENOG4105D06	uba thif-type nad fad binding protein
AXE84_08175	ENOG4108IUE	nitrate reductase beta subunit
AXE84_08190	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXE84_08200	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXE84_08220	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXE84_08240	ENOG4105CEI	nitrite reductase
AXE84_08250	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AXE84_08255	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AXE84_08260	ENOG4105E9K	Isocitrate dehydrogenase
AXE84_08270	ENOG4105EMN	RNA polymerase sigma factor
AXE84_08290	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AXE84_08300	ENOG4105C37	(CBS) domain
AXE84_08310	ENOG4105DR5	peptidase
AXE84_08335	ENOG4105C75	arginyL-tRNA synthetase
AXE84_08340	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AXE84_08350	ENOG4105D6E	homoserine dehydrogenase
AXE84_08355	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AXE84_08365	ENOG4108UZX	fmn reductase
AXE84_08375	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AXE84_08380	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AXE84_08385	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AXE84_08400	ENOG4108V4B	ThiJ pfpI
AXE84_08420	ENOG4108UW5	maltose o-acetyltransferase
AXE84_08425	ENOG4105CJQ	hydrolase, family 31
AXE84_08430	ENOG4105CG3	alpha amylase, catalytic region
AXE84_08435	ENOG4108DBC	nitroreductase
AXE84_08450	ENOG4105CMQ	Chloride channel
AXE84_08455	ENOG4105CTQ	phosphohexokinase
AXE84_08460	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AXE84_08490	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AXE84_08495	ENOG4105BZ1	(ABC) transporter
AXE84_08505	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AXE84_08520	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AXE84_08560	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AXE84_08575	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AXE84_08580	ENOG4105C31	Tryptophanyl-tRNA synthetase
AXE84_08590	ENOG4105BZJ	Electron transfer flavoprotein
AXE84_08595	ENOG4105C10	Electron transfer flavoprotein
AXE84_08600	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AXE84_08615	ENOG4105C3J	Cysteine desulfurase
AXE84_08635	ENOG41063PX	domain protein
AXE84_08650	ENOG4105DJZ	UPF0182 protein
AXE84_08670	ENOG4105CSR	polyphosphate kinase 2
AXE84_08675	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AXE84_08775	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AXE84_08780	ENOG4105CI1	PTS System
AXE84_08790	ENOG4105C5Y	PTS System
AXE84_08795	ENOG4105CI1	PTS System
AXE84_08800	ENOG4105FDP	GntR family transcriptional regulator
AXE84_08830	ENOG4105C9K	Endothelin-converting enzyme 1
AXE84_08850	ENOG4105D7W	serine acetyltransferase
AXE84_08860	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AXE84_08865	ENOG41067C8	50S ribosomal protein L32
AXE84_08880	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AXE84_08895	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AXE84_08900	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AXE84_08905	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AXE84_08910	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AXE84_08940	ENOG4105CG3	alpha amylase, catalytic region
AXE84_08945	ENOG4105FKQ	transcriptional regulator
AXE84_08950	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AXE84_08955	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
AXE84_08960	ENOG4105E5F	proteasome
AXE84_08965	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
AXE84_08970	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
AXE84_08980	ENOG4108JJB	ABC transporter
AXE84_09015	ENOG410635A	Membrane
AXE84_09020	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AXE84_09035	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AXE84_09040	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AXE84_09045	ENOG4105II7	pyrroline-5-carboxylate reductase
AXE84_09050	ENOG4105D3Y	Na H antiporter
AXE84_09055	ENOG4105EMU	Dehydrogenase
AXE84_09080	ENOG4105D75	Capsular exopolysaccharide family
AXE84_09090	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AXE84_09095	ENOG4105D3Q	Sugar transferase
AXE84_09130	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AXE84_09135	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AXE84_09140	ENOG4108UTZ	Dihydroxyacetone kinase
AXE84_09145	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AXE84_09155	ENOG4108IUX	(ABC) transporter
AXE84_09160	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AXE84_09170	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AXE84_09180	ENOG4105BZU	Histidine kinase
AXE84_09185	ENOG4105KCT	ABC transporter
AXE84_09190	ENOG4108M15	ABC transporter
AXE84_09205	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_09210	ENOG4105BZU	Histidine kinase
AXE84_09235	ENOG41082KU	UPF0109 protein
AXE84_09240	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AXE84_09250	ENOG4107QYR	Signal peptidase i
AXE84_09260	ENOG4107QYR	Signal peptidase i
AXE84_09265	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AXE84_09275	ENOG41080R2	UPF0102 protein
AXE84_09280	ENOG4105C0P	Mg chelatase subunit ChlI
AXE84_09295	ENOG4105Q36	FHA domain containing protein
AXE84_09305	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AXE84_09315	ENOG4105CE9	30S ribosomal protein S2
AXE84_09320	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AXE84_09325	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AXE84_09330	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AXE84_09340	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AXE84_09350	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AXE84_09355	ENOG4105DZP	Membrane-associated zinc metalloprotease
AXE84_09360	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AXE84_09365	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AXE84_09400	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AXE84_09430	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AXE84_09435	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AXE84_09450	ENOG4107QX8	SPFH domain, Band 7 family protein
AXE84_09460	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AXE84_09465	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AXE84_09475	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXE84_09485	ENOG4105DTN	riboflavin biosynthesis protein ribF
AXE84_09500	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AXE84_09510	ENOG4105E1F	short-chain dehydrogenase reductase
AXE84_09515	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AXE84_09535	ENOG4105CEY	Amp-dependent synthetase and ligase
AXE84_09540	ENOG4105CEY	Amp-dependent synthetase and ligase
AXE84_09570	ENOG4108V6E	Cell division protein mraZ
AXE84_09575	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AXE84_09585	ENOG4105CJN	penicillin-binding protein
AXE84_09590	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AXE84_09600	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AXE84_09605	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AXE84_09620	ENOG4105DFU	Cell wall formation (By similarity)
AXE84_09630	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AXE84_09635	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AXE84_09640	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AXE84_09670	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AXE84_09675	ENOG4105C0B	DNA polymerase III (alpha subunit)
AXE84_09680	ENOG4105C94	Transporter
AXE84_09685	ENOG410848D	S4 domain protein YaaA
AXE84_09705	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AXE84_09710	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AXE84_09730	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AXE84_09745	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AXE84_09750	ENOG4105EEQ	Na H antiporter
AXE84_09755	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AXE84_09760	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AXE84_09775	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AXE84_09780	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AXE84_09790	ENOG4105KNE	Phosphatidate cytidylyltransferase
AXE84_09810	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AXE84_09820	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AXE84_09825	ENOG41084BS	50S ribosomal protein L35
AXE84_09830	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AXE84_09850	ENOG4105CDA	abc transporter atp-binding protein
AXE84_09855	ENOG4107RP9	extracellular solute-binding protein, family 3
AXE84_09860	ENOG4105DRP	amino acid AbC transporter
AXE84_09865	ENOG4105DRP	amino acid AbC transporter
AXE84_09885	ENOG4105CIG	ABC transporter
AXE84_09895	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AXE84_09900	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AXE84_09910	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AXE84_09915	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AXE84_09920	ENOG4105CAS	nag kinase
AXE84_09925	ENOG4105C8Y	Acetylornithine aminotransferase
AXE84_09930	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AXE84_09935	ENOG4105CDH	Citrulline--aspartate ligase
AXE84_09940	ENOG4105TMB	Formate nitrite transporter
AXE84_09945	ENOG4105CH7	arginosuccinase
AXE84_09950	ENOG4108VX5	3-methyladenine DNA glycosylase
AXE84_09970	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AXE84_10000	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AXE84_10015	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AXE84_10020	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AXE84_10055	ENOG4105ETE	Transcriptional regulator (LacI family
AXE84_10070	ENOG4105DRS	transport system, permease
AXE84_10075	ENOG4108HKT	sucrose-6-phosphate hydrolase
AXE84_10095	ENOG4105JRK	feS assembly protein SufD
AXE84_10100	ENOG4105C3K	feS assembly ATPase SufC
AXE84_10110	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AXE84_10115	ENOG4105VG1	fes assembly suf system protein
AXE84_10120	ENOG4105K78	MarR family Transcriptional regulator
AXE84_10145	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AXE84_10160	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AXE84_10180	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AXE84_10190	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AXE84_10205	ENOG4105EG2	ABC transporter, permease
AXE84_10210	ENOG4105D56	permease protein
AXE84_10215	ENOG4107FKK	extracellular solute-binding protein family 1
AXE84_10225	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AXE84_10230	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AXE84_10255	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AXE84_10265	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AXE84_10270	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AXE84_10280	ENOG4108IJ0	Aspartate ammonia-lyase
AXE84_10290	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AXE84_10345	ENOG4105EGD	dinuclear metal center protein, YbgI family
AXE84_10355	ENOG4107XFJ	UPF0246 protein
AXE84_10375	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AXE84_10380	ENOG4105C5F	glutamine synthetase
AXE84_10385	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AXE84_10390	ENOG4108TGR	phosphatase
AXE84_10400	ENOG4105E5Q	amino acid AbC transporter
AXE84_10410	ENOG4105C5F	glutamine synthetase
AXE84_10420	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AXE84_10425	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AXE84_10435	ENOG4107QK7	reductase
AXE84_10460	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AXE84_10475	ENOG4107XM9	(LipO)protein
AXE84_10485	ENOG4105C6N	Formate acetyltransferase
AXE84_10545	ENOG4105C22	threonyL-tRNA synthetase
AXE84_10555	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
AXE84_10565	ENOG4105E2K	Glycosyl transferase (Group 1
AXE84_10580	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AXE84_10585	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AXE84_10590	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AXE84_10595	ENOG4105CDY	transcriptional regulatory protein
AXE84_10600	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AXE84_10605	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AXE84_10610	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AXE84_10620	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AXE84_10625	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AXE84_10630	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AXE84_10635	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AXE84_10645	ENOG4107TXC	Transcriptional regulator
AXE84_10655	ENOG4105C99	atpase involved in dna repair
AXE84_10670	ENOG4105CUT	histidyl-tRNA synthetase
AXE84_10680	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AXE84_10700	ENOG4105D7T	ABC transporter
AXE84_10730	ENOG4105C9M	aspartyl-trna synthetase
AXE84_10760	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AXE84_10770	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AXE84_10775	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AXE84_10780	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AXE84_10795	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AXE84_10800	ENOG4105D49	3-dehydroquinate synthase
AXE84_10805	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AXE84_10810	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AXE84_10815	ENOG410803B	Involved in the transcription termination process (By similarity)
AXE84_10840	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AXE84_10845	ENOG4105CXT	aspartate transcarbamylase
AXE84_10850	ENOG4105CD3	dihydroorotase
AXE84_10855	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AXE84_10860	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AXE84_10865	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AXE84_10875	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AXE84_10880	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AXE84_10890	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AXE84_10905	ENOG4105CSH	Transporter
AXE84_10925	ENOG4105DBV	ornithine carbamoyltransferase
AXE84_10930	ENOG4105CEU	Arginine dihydrolase
AXE84_10940	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AXE84_10950	ENOG4105DJV	ribulose-phosphate 3-epimerase
AXE84_10955	ENOG4108JIK	carboxylase
AXE84_10960	ENOG4105D8K	carboxyl transferase
AXE84_10965	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AXE84_10970	ENOG4105IBS	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AXE84_10975	ENOG4105CK7	Sodium proline symporter
AXE84_10980	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
AXE84_10985	ENOG4107XKF	NMT1 THI5 Like Domain Protein
AXE84_10990	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AXE84_10995	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
AXE84_11015	ENOG4105DA5	(ABC) transporter
AXE84_11020	ENOG4105WH1	Two component transcriptional regulator luxr family
AXE84_11025	ENOG4105BZU	Histidine kinase
AXE84_11045	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AXE84_11050	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AXE84_11065	ENOG4105CKW	Inner membrane protein yedI
AXE84_11070	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AXE84_11085	ENOG4105CTQ	phosphohexokinase
AXE84_11090	ENOG4108Z7F	N-acetyltransferase
AXE84_11095	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AXE84_11100	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
AXE84_11105	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AXE84_11115	ENOG4105ETE	Transcriptional regulator (LacI family
AXE84_11120	ENOG4105C5Y	PTS System
AXE84_11125	ENOG4107R3K	hydrolase
AXE84_11140	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AXE84_11145	ENOG4105CPC	Aldo Keto reductase
AXE84_11165	ENOG4108UW8	fha domain-containing protein
AXE84_11175	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AXE84_11190	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
AXE84_11220	ENOG41085GJ	domain protein
AXE84_11225	ENOG4107QP8	phosphohexose isomerase
AXE84_11235	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AXE84_11250	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AXE84_11255	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AXE84_11275	ENOG4105CP7	Triose-phosphate isomerase
AXE84_11280	ENOG4105BZA	Phosphoglycerate kinase
AXE84_11285	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AXE84_11290	ENOG4105CIE	May be required for sporulation (By similarity)
AXE84_11300	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AXE84_11305	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AXE84_11315	ENOG4105X1Q	TOBE domain protein
AXE84_11320	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AXE84_11375	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AXE84_11380	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AXE84_11390	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AXE84_11400	ENOG4105KA0	thioesterase Superfamily protein
AXE84_11425	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AXE84_11430	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AXE84_11450	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AXE84_11460	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
AXE84_11470	ENOG4105E5F	proteasome
AXE84_11475	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
AXE84_11490	ENOG4105EZR	dyp-type peroxidase family protein
AXE84_11505	ENOG4105CUC	YeeE YedE family protein
AXE84_11515	ENOG4105CPC	Aldo Keto reductase
AXE84_11520	ENOG4108IPW	abc transporter atp-binding protein
AXE84_11525	ENOG4105CM4	permease protein
AXE84_11530	ENOG4105DHS	permease protein
AXE84_11545	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
AXE84_11550	ENOG4105DGW	oligopeptidase A
AXE84_11560	ENOG4105C57	major facilitator superfamily
AXE84_11600	ENOG4105C0B	DNA polymerase III (alpha subunit)
AXE84_11620	ENOG4107104	thymidine kinase
AXE84_11625	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AXE84_11640	ENOG4108V1U	phospholipid-binding protein
AXE84_11645	ENOG4105EMU	Dehydrogenase
AXE84_11650	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AXE84_11665	ENOG4108IUW	ABC transporter
AXE84_11680	ENOG4107QN2	dihydrolipoyl dehydrogenase
AXE84_11695	ENOG4107QM5	aconitate hydratase
AXE84_11700	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AXE84_11705	ENOG4105C0X	amino acid
AXE84_11710	ENOG4107VEG	TrkA-N domain protein
AXE84_11755	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXE84_11770	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXE84_11790	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AXE84_11805	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AXE84_11810	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
AXE84_11845	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AXE84_11855	ENOG4105C5H	ABC transporter
AXE84_11885	ENOG4105DKW	ABC transporter
AXE84_11895	ENOG4107QPH	glycogen) synthase
AXE84_11900	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AXE84_11905	ENOG4105EAC	phosphoserine phosphatase
AXE84_11915	ENOG4105CHR	reductase
AXE84_11930	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AXE84_11945	ENOG4105CC5	ABC transporter
AXE84_11955	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AXE84_11960	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
AXE84_11965	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AXE84_11980	ENOG4105VZ8	Transcriptional regulator
AXE84_11985	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AXE84_11995	ENOG4105C26	Dehydrogenase
AXE84_12000	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AXE84_12010	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AXE84_12030	ENOG4107QWP	ABC-2 type transporter
AXE84_12035	ENOG4105CIG	ABC transporter
AXE84_12040	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AXE84_12050	ENOG4105DFA	alanine racemase domain protein
AXE84_12055	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AXE84_12060	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AXE84_12075	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AXE84_12095	ENOG4105DJ2	Major Facilitator Superfamily
AXE84_12100	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AXE84_12110	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AXE84_12120	ENOG4105CRQ	synthase (Component I)
AXE84_12125	ENOG4105RGK	anthranilate synthase component ii
AXE84_12140	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AXE84_12160	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AXE84_12165	ENOG4105DPH	UPF0371 protein
AXE84_12180	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AXE84_12185	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AXE84_12210	ENOG4105BZF	Glycosyl transferase (Group 1
AXE84_12215	ENOG4105D7A	ATP-binding protein
AXE84_12220	ENOG4105C8T	Leucyl-tRNA synthetase
AXE84_12230	ENOG4107ZUX	Histidine triad (HIT) protein
AXE84_12255	ENOG4105C8J	)-transporter
AXE84_12275	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AXE84_12290	ENOG4107TB6	phosphoglycerate mutase