locus-tag	class	description
AXF14_00055	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AXF14_00060	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AXF14_00085	ENOG4108RQ5	Beta-lactamase domain-containing protein
AXF14_00100	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AXF14_00120	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AXF14_00140	ENOG4108426	dNA-binding protein
AXF14_00145	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AXF14_00155	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AXF14_00160	ENOG4108JQ7	(ABC) transporter
AXF14_00175	ENOG4105DEF	Extracellular solute-binding protein, family 5
AXF14_00180	ENOG4107YCY	Transcriptional regulator
AXF14_00185	ENOG4105C2W	permease
AXF14_00210	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXF14_00230	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AXF14_00235	ENOG4105DR5	peptidase
AXF14_00240	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
AXF14_00245	ENOG4105CAK	Cell division ATP-binding protein ftsE
AXF14_00295	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AXF14_00315	ENOG4105C7B	Threonine dehydratase
AXF14_00320	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AXF14_00325	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AXF14_00350	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AXF14_00355	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AXF14_00360	ENOG4108ZP8	Acetolactate synthase small subunit
AXF14_00370	ENOG4105D0C	transport protein
AXF14_00410	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AXF14_00415	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AXF14_00420	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AXF14_00440	ENOG4105EC2	ftsk spoIIIe
AXF14_00470	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AXF14_00490	ENOG4105E90	ABC transporter
AXF14_00495	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
AXF14_00500	ENOG4108IJ8	ABC transporter
AXF14_00535	ENOG4105DQ4	alcohol dehydrogenase
AXF14_00560	ENOG4105C9Q	fumarate hydratase class II
AXF14_00565	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
AXF14_00605	ENOG4105CVJ	phosphoglycerate mutase
AXF14_00640	ENOG4105CH2	amidohydrolase
AXF14_00655	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXF14_00695	ENOG4108IUW	ABC transporter
AXF14_00735	ENOG4105DJZ	UPF0182 protein
AXF14_00785	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AXF14_00800	ENOG4105C10	Electron transfer flavoprotein
AXF14_00805	ENOG4105BZJ	Electron transfer flavoprotein
AXF14_00815	ENOG4105C31	Tryptophanyl-tRNA synthetase
AXF14_00820	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AXF14_00830	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AXF14_00860	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AXF14_00875	ENOG4105EG2	ABC transporter, permease
AXF14_00890	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AXF14_00935	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AXF14_00940	ENOG4105CTQ	phosphohexokinase
AXF14_00950	ENOG4105CG3	alpha amylase, catalytic region
AXF14_00955	ENOG4105C26	Dehydrogenase
AXF14_00970	ENOG4108IJG	ABC transporter substrate-binding protein
AXF14_00980	ENOG4108KQ5	Integrase catalytic subunit
AXF14_00985	ENOG4105CJQ	hydrolase, family 31
AXF14_00990	ENOG4108PSK	reductase
AXF14_00995	ENOG4105FKQ	transcriptional regulator
AXF14_01000	ENOG4105CG3	alpha amylase, catalytic region
AXF14_01015	ENOG4108JE9	extracellular solute-binding protein family 1
AXF14_01020	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
AXF14_01065	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AXF14_01070	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AXF14_01075	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AXF14_01090	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
AXF14_01100	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AXF14_01105	ENOG4105D6E	homoserine dehydrogenase
AXF14_01115	ENOG4108JJB	ABC transporter
AXF14_01130	ENOG4108KQ5	Integrase catalytic subunit
AXF14_01150	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AXF14_01155	ENOG4105C75	arginyL-tRNA synthetase
AXF14_01170	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AXF14_01175	ENOG4105DR5	peptidase
AXF14_01190	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AXF14_01205	ENOG4105WMN	AntiSigma factor
AXF14_01210	ENOG4105EMN	RNA polymerase sigma factor
AXF14_01235	ENOG4105E9K	Isocitrate dehydrogenase
AXF14_01240	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AXF14_01245	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AXF14_01275	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXF14_01295	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXF14_01305	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXF14_01320	ENOG4108IUE	nitrate reductase beta subunit
AXF14_01345	ENOG4105E2A	Dehydrogenase
AXF14_01350	ENOG4108KQ5	Integrase catalytic subunit
AXF14_01355	ENOG4105CHR	reductase
AXF14_01375	ENOG4107TK4	histidinol-phosphate phosphatase
AXF14_01380	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AXF14_01390	ENOG4105EYH	Exonuclease
AXF14_01430	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AXF14_01435	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AXF14_01440	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
AXF14_01445	ENOG4105G3P	Lipoprotein lpqB
AXF14_01450	ENOG4105BZU	Histidine kinase
AXF14_01455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXF14_01470	ENOG4108WQ6	secreted protein
AXF14_01475	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXF14_01495	ENOG4105W49	UPF0434 protein
AXF14_01520	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AXF14_01530	ENOG4105EIP	mannose-6-phosphate isomerase
AXF14_01545	ENOG4106MCE	EamA-like transporter family
AXF14_01550	ENOG4105KPE	licD family
AXF14_01565	ENOG4105K64	Glycosyl transferase, family 2
AXF14_01570	ENOG4105KPE	licD family
AXF14_01605	ENOG4105EY8	ABC transporter
AXF14_01615	ENOG4105H63	Glycosyl transferase, family 2
AXF14_01620	ENOG4105E2K	Glycosyl transferase (Group 1
AXF14_01655	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
AXF14_01680	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AXF14_01695	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AXF14_01725	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXF14_01745	ENOG4108KGH	TRANSCRIPTIONal
AXF14_01750	ENOG4108KGH	TRANSCRIPTIONal
AXF14_01755	ENOG4105CMR	udp-glucose 4-epimerase
AXF14_01760	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AXF14_01785	ENOG4105BZU	Histidine kinase
AXF14_01790	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXF14_01805	ENOG4107WR6	Maf-like protein
AXF14_01810	ENOG4105D8K	carboxyl transferase
AXF14_01825	ENOG4105WDJ	50S ribosomal protein L33
AXF14_01845	ENOG4108VPT	UPF0234 protein
AXF14_01850	ENOG4105D0M	Protease HtpX homolog
AXF14_01855	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AXF14_01880	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXF14_01890	ENOG4105D65	subunit l
AXF14_01895	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXF14_01905	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXF14_01910	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AXF14_01915	ENOG4108IEH	NADH dehydrogenase subunit g
AXF14_01920	ENOG4107QIZ	NADH dehydrogenase
AXF14_01930	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXF14_01935	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXF14_01940	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXF14_01955	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AXF14_01960	ENOG4105E4F	Isochorismate synthase
AXF14_01965	ENOG4105C0H	protease
AXF14_02030	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AXF14_02035	ENOG4107TCW	O-succinylbenzoate synthase
AXF14_02040	ENOG4105DBV	ornithine carbamoyltransferase
AXF14_02095	ENOG4105DTI	Phosphonopyruvate decarboxylase
AXF14_02140	ENOG4105CEU	Arginine dihydrolase
AXF14_02160	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_02165	ENOG4107SIQ	Naphthoate synthase
AXF14_02175	ENOG4105K6V	RNA polymerase
AXF14_02190	ENOG4105R3P	Inner membrane protein yagU
AXF14_02215	ENOG4108RH7	phosphoglycerate mutase
AXF14_02220	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AXF14_02260	ENOG4107SVN	transposase
AXF14_02270	ENOG4108Z4U	Ferredoxin
AXF14_02280	ENOG4105CI3	gtp-binding protein typa
AXF14_02290	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
AXF14_02300	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
AXF14_02325	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXF14_02330	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AXF14_02335	ENOG4105DEF	Extracellular solute-binding protein, family 5
AXF14_02340	ENOG4105DEN	Luciferase family
AXF14_02345	ENOG4105C09	Bile acid
AXF14_02370	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
AXF14_02375	ENOG4108NRW	Phospholipase, patatin family
AXF14_02380	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AXF14_02385	ENOG4105K5B	UPF0225 protein
AXF14_02390	ENOG4105DFM	M18 family aminopeptidase
AXF14_02395	ENOG4105D9U	N-acetyltransferase
AXF14_02480	ENOG4105W1Y	Transcriptional regulator
AXF14_02540	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
AXF14_02555	ENOG4105VEQ	Cold shock protein
AXF14_02580	ENOG4108YZN	class I peptide chain release factor
AXF14_02605	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AXF14_02615	ENOG4105CV8	reductase
AXF14_02625	ENOG4105CHM	Aminotransferase
AXF14_02640	ENOG4105C3G	gtp-binding protein
AXF14_02675	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AXF14_02680	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_02690	ENOG4107R3K	hydrolase
AXF14_02695	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AXF14_02700	ENOG4105D7K	pfkb domain protein
AXF14_02705	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AXF14_02720	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AXF14_02745	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AXF14_02755	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AXF14_02760	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AXF14_02780	ENOG4105C7B	Threonine dehydratase
AXF14_02785	ENOG4105C01	Dihydroxy-acid dehydratase
AXF14_02815	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_02820	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AXF14_02825	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AXF14_02855	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AXF14_02885	ENOG4108KQ5	Integrase catalytic subunit
AXF14_02890	ENOG4105PSV	Polysaccharide Biosynthesis Protein
AXF14_02950	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AXF14_02960	ENOG4105D3Q	Sugar transferase
AXF14_02970	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AXF14_02975	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXF14_02985	ENOG41067SE	Tetr family transcriptional regulator
AXF14_02995	ENOG4105C5H	ABC transporter
AXF14_03000	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AXF14_03005	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AXF14_03025	ENOG4105F8V	Hydrolase, tatD family
AXF14_03030	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AXF14_03045	ENOG4108RWI	nicotinamidase
AXF14_03095	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
AXF14_03105	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AXF14_03155	ENOG4105C7N	Xanthine uracil vitamin C permease
AXF14_03160	ENOG4105C5I	Dehydrogenase
AXF14_03180	ENOG4105CFI	type iii restriction protein res subunit
AXF14_03215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXF14_03220	ENOG4105BZU	Histidine kinase
AXF14_03235	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AXF14_03250	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AXF14_03290	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AXF14_03295	ENOG4105C8N	cysteinyl-tRNA synthetase
AXF14_03300	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AXF14_03305	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AXF14_03315	ENOG4108KQ5	Integrase catalytic subunit
AXF14_03340	ENOG4105F3R	pts system mannose fructose sorbose family iid
AXF14_03345	ENOG4105ETZ	PTS System
AXF14_03350	ENOG4108EQA	pts system
AXF14_03360	ENOG4105J7I	hydrolase
AXF14_03375	ENOG4108HKT	sucrose-6-phosphate hydrolase
AXF14_03390	ENOG4105EBR	Carboxylesterase
AXF14_03400	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AXF14_03410	ENOG4107RBB	ABC transporter, permease
AXF14_03430	ENOG4105F44	Two component transcriptional regulator, winged helix family
AXF14_03435	ENOG4106F60	Histidine kinase
AXF14_03440	ENOG4105KNI	merR family transcriptional Regulator
AXF14_03455	ENOG4108YYC	ycei family
AXF14_03475	ENOG4105KNI	merR family transcriptional Regulator
AXF14_03480	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AXF14_03495	ENOG4105CFG	Acts as a chaperone (By similarity)
AXF14_03505	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXF14_03590	ENOG4105E6M	Sulphatase-modifying factor protein
AXF14_03600	ENOG4105CIG	ABC transporter
AXF14_03690	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AXF14_03710	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AXF14_03715	ENOG4105EDR	glucose galactose transporter
AXF14_03725	ENOG4108RVA	ribokinase
AXF14_03730	ENOG4108DMH	HTH_ARAC
AXF14_03735	ENOG4106DSS	Tartrate dehydratase subunit alpha
AXF14_03740	ENOG4107GFK	fumarate
AXF14_03745	ENOG4107QPK	)-transporter
AXF14_03755	ENOG4105VT3	DNA binding domain protein, excisionase family
AXF14_03780	ENOG4108I5C	dEAD DEAH box helicase
AXF14_03810	ENOG4105C0D	helicase
AXF14_03875	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AXF14_03880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXF14_03910	ENOG4108UCS	ABC, transporter
AXF14_03935	ENOG4105DF6	Fe-S oxidoreductase
AXF14_03945	ENOG4108VW9	Membrane
AXF14_03960	ENOG4105E93	esterase
AXF14_03965	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AXF14_03970	ENOG4105EHG	Permease protein
AXF14_03980	ENOG4105D1H	recombination factor protein RarA
AXF14_03990	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
AXF14_04010	ENOG4108JJA	ABC, transporter
AXF14_04015	ENOG4105BZ1	(ABC) transporter
AXF14_04025	ENOG4105C28	cystathionine
AXF14_04035	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AXF14_04040	ENOG4105F9E	Shikimate 5-dehydrogenase
AXF14_04065	ENOG4105C8P	)-transporter
AXF14_04075	ENOG4107QKS	N-acylglucosamine 2-epimerase
AXF14_04085	ENOG410667J	hydrolase
AXF14_04090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AXF14_04095	ENOG4105C5Q	Transcriptional regulator
AXF14_04100	ENOG4107TE5	Lipid kinase
AXF14_04155	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AXF14_04180	ENOG4105KWG	Pfam:DUF1696
AXF14_04185	ENOG4105CB5	ATP-dependent DNA helicase recG
AXF14_04200	ENOG4105WYW	fructose-bisphosphate aldolase
AXF14_04215	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AXF14_04225	ENOG4105KME	endoribonuclease L-psp
AXF14_04245	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AXF14_04250	ENOG41082T9	Membrane
AXF14_04265	ENOG4105DIM	ABC transporter
AXF14_04270	ENOG4105CIG	ABC transporter
AXF14_04280	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AXF14_04285	ENOG4105CTZ	aminopeptidase c
AXF14_04290	ENOG4107QTF	adenylosuccinate lyase
AXF14_04300	ENOG4105VPX	protein, conserved in bacteria
AXF14_04320	ENOG4108KQ5	Integrase catalytic subunit
AXF14_04330	ENOG4108SHN	Glycosyl transferase, family 2
AXF14_04345	ENOG4105CJ1	ABC, transporter
AXF14_04365	ENOG4107QNE	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AXF14_04370	ENOG4108JB8	alcohol dehydrogenase
AXF14_04380	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AXF14_04395	ENOG4105ECY	inositol monophosphatase
AXF14_04400	ENOG4105CPQ	Dehydrogenase
AXF14_04405	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AXF14_04420	ENOG4105C85	amino acid
AXF14_04430	ENOG41085J0	Protein CrcB homolog
AXF14_04435	ENOG4108680	CrcB-like protein
AXF14_04440	ENOG4105DKQ	ROK family
AXF14_04445	ENOG4107QRI	Phosphoketolase
AXF14_04465	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_04495	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AXF14_04510	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AXF14_04550	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AXF14_04560	ENOG4107WGA	YidE YbjL
AXF14_04565	ENOG4105ZMH	deoxynucleoside kinase
AXF14_04575	ENOG4105D22	carbon starvation protein
AXF14_04600	ENOG4105TV9	FHA Domain-Containing protein
AXF14_04605	ENOG4105HZM	Fha domain containing protein
AXF14_04620	ENOG4105CJN	penicillin-binding protein
AXF14_04625	ENOG4107TPY	serine threonine protein kinase
AXF14_04635	ENOG4108U4N	(sortase) family
AXF14_04645	ENOG4105CV8	reductase
AXF14_04680	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXF14_04685	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXF14_04690	ENOG4105K7N	UPF0232 protein
AXF14_04695	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AXF14_04700	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AXF14_04705	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AXF14_04710	ENOG41084CH	50S ribosomal protein l34
AXF14_04715	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AXF14_04720	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AXF14_04725	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AXF14_04735	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AXF14_04740	ENOG4107QJE	Chromosome Partitioning Protein
AXF14_04755	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXF14_04760	ENOG4105D98	threonine synthase
AXF14_04765	ENOG4108UW5	maltose o-acetyltransferase
AXF14_04770	ENOG4105K63	Thioredoxin
AXF14_04775	ENOG4105C3M	thioredoxin reductase
AXF14_04795	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AXF14_04800	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AXF14_04820	ENOG4107TXC	Transcriptional regulator
AXF14_04835	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
AXF14_04840	ENOG4107YH6	single-stranded DNA-binding protein
AXF14_04845	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AXF14_04850	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AXF14_04860	ENOG4105CDU	Replicative dna helicase
AXF14_04865	ENOG4105DWF	phosphomethylpyrimidine kinase
AXF14_04875	ENOG4107QW3	Sucrose phosphorylase
AXF14_04880	ENOG4105EJQ	L-serine dehydratase
AXF14_04905	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AXF14_04910	ENOG4105VTW	prevent-host-death family
AXF14_04915	ENOG4105CG3	alpha amylase, catalytic region
AXF14_04965	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_04990	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AXF14_04995	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AXF14_05015	ENOG4107FQX	Alpha-acetolactate decarboxylase
AXF14_05030	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AXF14_05040	ENOG4106KNT	transcriptional regulator
AXF14_05045	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AXF14_05060	ENOG4107S1E	Beta-lactamase
AXF14_05070	ENOG4107V9H	nitrite transporter
AXF14_05090	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AXF14_05135	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AXF14_05150	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AXF14_05155	ENOG4108UMI	ABC transporter, permease
AXF14_05165	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AXF14_05170	ENOG4105C94	Transporter
AXF14_05175	ENOG4108Z6B	deaminase
AXF14_05180	ENOG4108UW5	maltose o-acetyltransferase
AXF14_05210	ENOG4105CPN	adenine deaminase
AXF14_05215	ENOG4105CQ7	ATP-dependent helicase
AXF14_05260	ENOG4105C2W	permease
AXF14_05295	ENOG4105CMT	Dihydroxyacetone kinase
AXF14_05300	ENOG4108UTZ	Dihydroxyacetone kinase
AXF14_05305	ENOG4105VDH	Dihydroxyacetone kinase
AXF14_05335	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AXF14_05340	ENOG4105CFH	Aspartokinase
AXF14_05370	ENOG41080RH	Thioredoxin
AXF14_05385	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AXF14_05390	ENOG4105D52	delta-aminolevulinic acid dehydratase
AXF14_05410	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AXF14_05420	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AXF14_05425	ENOG4107JTW	chlorite dismutase
AXF14_05435	ENOG4105CE1	Ferrous iron transport protein b
AXF14_05445	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AXF14_05460	ENOG4105CBD	Diacylglycerol kinase
AXF14_05470	ENOG4105DIN	metallophosphoesterase
AXF14_05475	ENOG4105BZ4	penicillin-binding protein
AXF14_05485	ENOG4105IJJ	transcriptional regulator, crp fnr family
AXF14_05505	ENOG4108UMN	azlc family
AXF14_05575	ENOG4105D3R	alkyl hydroperoxide reductase
AXF14_05580	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AXF14_05590	ENOG4105DEN	Luciferase family
AXF14_05610	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AXF14_05635	ENOG4105BZU	Histidine kinase
AXF14_05640	ENOG4108KQ5	Integrase catalytic subunit
AXF14_05645	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXF14_05655	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AXF14_05665	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AXF14_05675	ENOG4107QRG	dna polymerase iii
AXF14_05685	ENOG4105HDK	L-asparaginase
AXF14_05705	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AXF14_05710	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AXF14_05720	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXF14_05735	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AXF14_05745	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AXF14_05755	ENOG4105DET	Rhamnulokinase
AXF14_05775	ENOG4105DIK	(ABC) transporter
AXF14_05785	ENOG4105K8R	UPF0145 protein
AXF14_05800	ENOG4108RVA	ribokinase
AXF14_05810	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AXF14_05815	ENOG4105CQ7	ATP-dependent helicase
AXF14_05840	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AXF14_05845	ENOG4106N3A	copper homeostasis protein cutc
AXF14_05860	ENOG4105BZ1	(ABC) transporter
AXF14_05870	ENOG4107ZT3	family UPF0126
AXF14_05950	ENOG4105W5Q	DNA repair protein (RadC
AXF14_05955	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXF14_06035	ENOG4105DHP	deoxycytidine triphosphate deaminase
AXF14_06045	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AXF14_06050	ENOG4108DBC	nitroreductase
AXF14_06070	ENOG4105EMU	Dehydrogenase
AXF14_06075	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AXF14_06085	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
AXF14_06100	ENOG4107QIV	Cytochrome c biogenesis protein
AXF14_06105	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
AXF14_06110	ENOG4105CRE	cytochrome C
AXF14_06120	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AXF14_06135	ENOG4107RCW	fructose-bisphosphate aldolase
AXF14_06165	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AXF14_06195	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AXF14_06215	ENOG4105C12	Phosphoribosylglycinamide synthetase
AXF14_06220	ENOG4105C8V	SAICAR synthetase
AXF14_06240	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AXF14_06245	ENOG41088YS	Glycosyl transferase (Group 1
AXF14_06250	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AXF14_06260	ENOG4105CAY	ferredoxin--nadp reductase
AXF14_06270	ENOG4105D82	Glutamate dehydrogenase
AXF14_06285	ENOG4105E98	transcriptional regulator DeoR family
AXF14_06295	ENOG4105DM4	PTS System
AXF14_06300	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AXF14_06305	ENOG4105C6F	GntR Family Transcriptional Regulator
AXF14_06315	ENOG4105ZXK	Dehydrogenase
AXF14_06320	ENOG4105C6Z	Gluconate
AXF14_06330	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AXF14_06360	ENOG4107SVN	transposase
AXF14_06385	ENOG4105BZ1	(ABC) transporter
AXF14_06400	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AXF14_06430	ENOG4105E0X	reductase
AXF14_06450	ENOG4105C6Z	Gluconate
AXF14_06455	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AXF14_06465	ENOG4105C1J	atp-dependent rna helicase
AXF14_06520	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AXF14_06545	ENOG4107NHD	transcriptional regulator
AXF14_06560	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
AXF14_06565	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AXF14_06575	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AXF14_06590	ENOG4105BZU	Histidine kinase
AXF14_06595	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_06630	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AXF14_06645	ENOG4105C57	major facilitator superfamily
AXF14_06655	ENOG4108S01	response regulator
AXF14_06670	ENOG4105CT4	transporter
AXF14_06685	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AXF14_06690	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXF14_06705	ENOG4108SEA	Esterase
AXF14_06710	ENOG4105FF5	Membrane
AXF14_06720	ENOG4105DWV	Homoserine O-trans-acetylase
AXF14_06725	ENOG4108IQK	o-acetylhomoserine
AXF14_06735	ENOG4105F0N	pyrophosphate phospho-hydrolase
AXF14_06740	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
AXF14_06750	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AXF14_06760	ENOG4105EUJ	GTP cyclohydrolase i
AXF14_06765	ENOG4107QPD	alcohol dehydrogenase
AXF14_06770	ENOG4105EEI	dihydropteroate synthase
AXF14_06800	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AXF14_06805	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AXF14_06820	ENOG4105CRK	lysyL-tRNA synthetase
AXF14_06855	ENOG4105DEI	Mannitol dehydrogenase
AXF14_06870	ENOG41080R8	Conserved Protein
AXF14_06880	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AXF14_06885	ENOG4105DAA	L-lactate
AXF14_06890	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AXF14_06895	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AXF14_06905	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AXF14_06915	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AXF14_06920	ENOG4105DKT	Transcriptional regulator
AXF14_06940	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
AXF14_06950	ENOG4108MES	Periplasmic binding protein
AXF14_06955	ENOG4105DQ5	transport system permease protein
AXF14_06965	ENOG4107QNK	)-transporter
AXF14_06975	ENOG4105DKT	Transcriptional regulator
AXF14_06985	ENOG4105CMT	Dihydroxyacetone kinase
AXF14_06990	ENOG4105CMT	Dihydroxyacetone kinase
AXF14_07005	ENOG4105DT3	PTS system, galactitol-specific IIc component
AXF14_07020	ENOG4108IPW	abc transporter atp-binding protein
AXF14_07025	ENOG4105CM4	permease protein
AXF14_07045	ENOG4107WI4	Aldose-1-epimerase
AXF14_07060	ENOG4105CZN	Potassium uptake protein
AXF14_07090	ENOG4105BZG	amino acid carrier protein
AXF14_07105	ENOG410683Z	Preprotein translocase SecE subunit
AXF14_07110	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AXF14_07115	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AXF14_07120	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AXF14_07135	ENOG4108VZM	50s ribosomal protein L10
AXF14_07140	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AXF14_07145	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXF14_07150	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXF14_07155	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AXF14_07160	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AXF14_07165	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AXF14_07170	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AXF14_07175	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AXF14_07180	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AXF14_07185	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AXF14_07190	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AXF14_07195	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXF14_07200	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AXF14_07205	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AXF14_07210	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AXF14_07215	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AXF14_07220	ENOG41082SA	50s ribosomal protein l29
AXF14_07225	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AXF14_07230	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AXF14_07235	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AXF14_07240	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXF14_07245	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AXF14_07255	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AXF14_07265	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AXF14_07270	ENOG410849U	50S ribosomal protein L30
AXF14_07275	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AXF14_07285	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AXF14_07295	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AXF14_07300	ENOG41067V7	50S ribosomal protein L36
AXF14_07305	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXF14_07310	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AXF14_07315	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXF14_07320	ENOG4108ZT0	50S ribosomal protein l17
AXF14_07335	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AXF14_07340	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AXF14_07355	ENOG4105CS9	pantothenic acid kinase
AXF14_07360	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AXF14_07375	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AXF14_07380	ENOG4108097	ATP-binding protein
AXF14_07410	ENOG4105E33	succinate dehydrogenase
AXF14_07415	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AXF14_07420	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
AXF14_07435	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AXF14_07440	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AXF14_07445	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AXF14_07455	ENOG4107QVP	Dehydrogenase
AXF14_07460	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
AXF14_07465	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
AXF14_07475	ENOG410849S	phosphocarrier protein (HPr)
AXF14_07480	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AXF14_07490	ENOG4105CSC	Glucose uptake protein
AXF14_07510	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AXF14_07520	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_07525	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AXF14_07570	ENOG4105EYF	MMPL domain protein
AXF14_07580	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AXF14_07620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXF14_07625	ENOG4108Z0Z	intracellular protease Pfpi family
AXF14_07655	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_07670	ENOG4105ESV	Glycosyl transferase, family 4
AXF14_07680	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
AXF14_07685	ENOG4105ZA1	atp synthase
AXF14_07690	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AXF14_07695	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AXF14_07700	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AXF14_07705	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AXF14_07710	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AXF14_07715	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AXF14_07725	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AXF14_07735	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
AXF14_07745	ENOG4105CE4	GlcNAc 6-P deacetylase
AXF14_07780	ENOG4108638	50S ribosomal protein L36
AXF14_07785	ENOG4105NRA	50s ribosomal protein l31 type b
AXF14_07790	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AXF14_07795	ENOG4105W0E	50S ribosomal protein L33
AXF14_07800	ENOG4105KDC	50s ribosomal protein l28
AXF14_07810	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AXF14_07815	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AXF14_07830	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AXF14_07835	ENOG4105D7K	pfkb domain protein
AXF14_07840	ENOG4108HKT	sucrose-6-phosphate hydrolase
AXF14_07845	ENOG4105EDQ	levansucrase EC 2.4.1.10
AXF14_07860	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXF14_07865	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXF14_07875	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AXF14_07880	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_07885	ENOG4105CNT	hydrolase family 2
AXF14_07890	ENOG4105CT4	transporter
AXF14_07910	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AXF14_07915	ENOG4105DIH	basic membrane
AXF14_07925	ENOG4105UIB	(ABC) transporter
AXF14_07945	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AXF14_07950	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AXF14_07960	ENOG4105DIK	(ABC) transporter
AXF14_07970	ENOG4105CC5	ABC transporter
AXF14_07980	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AXF14_08005	ENOG4108IYU	L-aspartate oxidase
AXF14_08010	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AXF14_08020	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
AXF14_08025	ENOG4108URH	decarboxylase
AXF14_08040	ENOG4105D1F	ATP-binding protein
AXF14_08055	ENOG4105CJW	magnesium transporter
AXF14_08070	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
AXF14_08080	ENOG4105PGM	cation diffusion facilitator family transporter
AXF14_08090	ENOG4107T6F	Xaa-Pro aminopeptidase
AXF14_08105	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AXF14_08150	ENOG4108KQ5	Integrase catalytic subunit
AXF14_08155	ENOG4108KQ5	Integrase catalytic subunit
AXF14_08160	ENOG4105C1J	atp-dependent rna helicase
AXF14_08175	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AXF14_08180	ENOG4105CMJ	mandelate racemase muconate lactonizing
AXF14_08270	ENOG4108M0I	Transcriptional regulator
AXF14_08275	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AXF14_08290	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AXF14_08305	ENOG4105C5Y	PTS System
AXF14_08315	ENOG4105FDP	GntR family transcriptional regulator
AXF14_08335	ENOG4105C9K	Endothelin-converting enzyme 1
AXF14_08360	ENOG4105D7W	serine acetyltransferase
AXF14_08370	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AXF14_08375	ENOG41067C8	50S ribosomal protein L32
AXF14_08395	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AXF14_08405	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AXF14_08410	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AXF14_08415	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AXF14_08420	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AXF14_08465	ENOG4105II7	pyrroline-5-carboxylate reductase
AXF14_08500	ENOG4105CG3	alpha amylase, catalytic region
AXF14_08505	ENOG4105C5Y	PTS System
AXF14_08520	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AXF14_08535	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AXF14_08540	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AXF14_08545	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AXF14_08565	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AXF14_08580	ENOG4108UTZ	Dihydroxyacetone kinase
AXF14_08585	ENOG4105VDH	Dihydroxyacetone kinase
AXF14_08590	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AXF14_08605	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AXF14_08620	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AXF14_08635	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AXF14_08660	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXF14_08665	ENOG4105K5M	30s ribosomal protein S16
AXF14_08670	ENOG41082KU	UPF0109 protein
AXF14_08675	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AXF14_08680	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AXF14_08695	ENOG4107QYR	Signal peptidase i
AXF14_08700	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AXF14_08715	ENOG4105C0P	Mg chelatase subunit ChlI
AXF14_08725	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AXF14_08735	ENOG4105CE9	30S ribosomal protein S2
AXF14_08740	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AXF14_08750	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AXF14_08760	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AXF14_08770	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AXF14_08780	ENOG4105DZP	Membrane-associated zinc metalloprotease
AXF14_08795	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AXF14_08835	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AXF14_08840	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AXF14_08850	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AXF14_08855	ENOG4105CHV	Transcription elongation factor NusA
AXF14_08865	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AXF14_08890	ENOG4105FR1	rard protein
AXF14_08900	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AXF14_08910	ENOG4105DTN	riboflavin biosynthesis protein ribF
AXF14_08920	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AXF14_08925	ENOG4105C1V	Peptidase, M16
AXF14_08940	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AXF14_08950	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AXF14_08955	ENOG4105CEY	Amp-dependent synthetase and ligase
AXF14_08975	ENOG4105DJB	Major Facilitator Superfamily
AXF14_08985	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AXF14_08995	ENOG4108V6E	Cell division protein mraZ
AXF14_09000	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AXF14_09010	ENOG4105CJN	penicillin-binding protein
AXF14_09015	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AXF14_09025	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AXF14_09030	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AXF14_09035	ENOG4105CNI	cell division protein FtsW
AXF14_09045	ENOG4105DFU	Cell wall formation (By similarity)
AXF14_09055	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AXF14_09060	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AXF14_09065	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AXF14_09075	ENOG4107VQS	DivIVA family
AXF14_09100	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AXF14_09105	ENOG4105C0B	DNA polymerase III (alpha subunit)
AXF14_09120	ENOG410848D	S4 domain protein YaaA
AXF14_09145	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AXF14_09165	ENOG41082EK	Restriction modification system DNA (Specificity
AXF14_09205	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AXF14_09210	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AXF14_09240	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AXF14_09245	ENOG4105D7N	magnesium and cobalt transport protein CorA
AXF14_09250	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AXF14_09285	ENOG4105CMG	Carbohydrate kinase
AXF14_09295	ENOG4108JQ1	Dehydrogenase
AXF14_09300	ENOG4105DT3	PTS system, galactitol-specific IIc component
AXF14_09305	ENOG4105EEQ	Na H antiporter
AXF14_09315	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AXF14_09320	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AXF14_09330	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AXF14_09335	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AXF14_09345	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AXF14_09350	ENOG41084BS	50S ribosomal protein L35
AXF14_09355	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AXF14_09365	ENOG4108RWN	rrna methyltransferase
AXF14_09375	ENOG4105DRS	transport system, permease
AXF14_09380	ENOG4108JE9	extracellular solute-binding protein family 1
AXF14_09390	ENOG4105D7K	pfkb domain protein
AXF14_09395	ENOG4105F8D	glycoside hydrolase family 4
AXF14_09400	ENOG4105CDA	abc transporter atp-binding protein
AXF14_09405	ENOG4107UBR	Extracellular solute-binding protein family 3
AXF14_09410	ENOG4105EAD	ABC transporter
AXF14_09415	ENOG4105DRP	amino acid AbC transporter
AXF14_09420	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AXF14_09425	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AXF14_09440	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AXF14_09445	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AXF14_09450	ENOG4105CAS	nag kinase
AXF14_09455	ENOG4105C8Y	Acetylornithine aminotransferase
AXF14_09460	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AXF14_09465	ENOG4105CDH	Citrulline--aspartate ligase
AXF14_09475	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AXF14_09485	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AXF14_09525	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AXF14_09530	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AXF14_09560	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AXF14_09570	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_09585	ENOG4105DRS	transport system, permease
AXF14_09595	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_09605	ENOG4105DIW	FeS assembly protein SUFB
AXF14_09615	ENOG4105C3K	feS assembly ATPase SufC
AXF14_09625	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AXF14_09630	ENOG4105VG1	fes assembly suf system protein
AXF14_09650	ENOG4105K78	MarR family Transcriptional regulator
AXF14_09660	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AXF14_09675	ENOG4105CPC	Aldo Keto reductase
AXF14_09685	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AXF14_09695	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_09700	ENOG4108IUK	alpha amylase, catalytic
AXF14_09705	ENOG4105EG2	ABC transporter, permease
AXF14_09710	ENOG4105D56	permease protein
AXF14_09715	ENOG4107FKK	extracellular solute-binding protein family 1
AXF14_09725	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AXF14_09730	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AXF14_09745	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AXF14_09765	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AXF14_09770	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AXF14_09790	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AXF14_09805	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AXF14_09815	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_09820	ENOG4105BZU	Histidine kinase
AXF14_09845	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AXF14_09880	ENOG4105CHM	Aminotransferase
AXF14_09895	ENOG4105EGD	dinuclear metal center protein, YbgI family
AXF14_09905	ENOG4105D1Q	UPF0246 protein
AXF14_09935	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AXF14_09940	ENOG4105C5F	glutamine synthetase
AXF14_09945	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AXF14_09955	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AXF14_09965	ENOG4105E5Q	amino acid AbC transporter
AXF14_09970	ENOG4107UBR	Extracellular solute-binding protein family 3
AXF14_09980	ENOG4105C5F	glutamine synthetase
AXF14_09990	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AXF14_09995	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AXF14_10000	ENOG4108QVN	serine threonine protein kinase
AXF14_10015	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AXF14_10035	ENOG4105C6N	Formate acetyltransferase
AXF14_10110	ENOG4105C22	threonyL-tRNA synthetase
AXF14_10125	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
AXF14_10130	ENOG4105E2K	Glycosyl transferase (Group 1
AXF14_10145	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AXF14_10150	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AXF14_10155	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AXF14_10160	ENOG4105CDY	transcriptional regulatory protein
AXF14_10165	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AXF14_10170	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AXF14_10175	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AXF14_10185	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AXF14_10190	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AXF14_10195	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AXF14_10200	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AXF14_10240	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AXF14_10245	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AXF14_10260	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AXF14_10290	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AXF14_10295	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AXF14_10310	ENOG4105F9F	transposase
AXF14_10350	ENOG4105F9F	transposase
AXF14_10360	ENOG4105D7T	ABC transporter
AXF14_10385	ENOG4105C9M	aspartyl-trna synthetase
AXF14_10395	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AXF14_10405	ENOG4107R13	MMPL domain protein
AXF14_10415	ENOG4105HF0	Membrane
AXF14_10420	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AXF14_10425	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AXF14_10430	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AXF14_10440	ENOG4105E2X	shikimate dehydrogenase
AXF14_10445	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AXF14_10450	ENOG4105D49	3-dehydroquinate synthase
AXF14_10460	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AXF14_10470	ENOG4107S9F	NmrA family
AXF14_10475	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AXF14_10480	ENOG4105CXT	aspartate transcarbamylase
AXF14_10485	ENOG4105CD3	dihydroorotase
AXF14_10490	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AXF14_10495	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AXF14_10500	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AXF14_10505	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AXF14_10510	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AXF14_10515	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AXF14_10525	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AXF14_10530	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AXF14_10550	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AXF14_10560	ENOG4105DJV	ribulose-phosphate 3-epimerase
AXF14_10570	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AXF14_10580	ENOG4108JIK	carboxylase
AXF14_10585	ENOG4105D8K	carboxyl transferase
AXF14_10590	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AXF14_10620	ENOG4105CK7	Sodium proline symporter
AXF14_10625	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
AXF14_10630	ENOG4107XKF	NMT1 THI5 Like Domain Protein
AXF14_10635	ENOG4105T2N	Domain of unknown function (DUF2382)
AXF14_10640	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AXF14_10645	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
AXF14_10655	ENOG4105DA5	(ABC) transporter
AXF14_10660	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_10665	ENOG4105BZU	Histidine kinase
AXF14_10705	ENOG4105CKW	Inner membrane protein yedI
AXF14_10715	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AXF14_10725	ENOG4105CTQ	phosphohexokinase
AXF14_10735	ENOG4105CIS	alcohol dehydrogenase
AXF14_10745	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
AXF14_10750	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AXF14_10760	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_10765	ENOG4105C5Y	PTS System
AXF14_10780	ENOG4107QNK	)-transporter
AXF14_10790	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AXF14_10795	ENOG4105CPC	Aldo Keto reductase
AXF14_10825	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AXF14_10845	ENOG4107QM2	Aldo Keto reductase
AXF14_10880	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AXF14_10885	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AXF14_10895	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
AXF14_10900	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AXF14_10915	ENOG4105D06	uba thif-type nad fad binding protein
AXF14_10920	ENOG4107QP8	phosphohexose isomerase
AXF14_10925	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AXF14_10940	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AXF14_10965	ENOG4105CP7	Triose-phosphate isomerase
AXF14_10970	ENOG4105BZA	Phosphoglycerate kinase
AXF14_10975	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AXF14_10980	ENOG4105CIE	May be required for sporulation (By similarity)
AXF14_10985	ENOG4105CHW	UPF0052 protein
AXF14_10990	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AXF14_10995	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AXF14_11005	ENOG4105F4R	Transcriptional regulator mode
AXF14_11010	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AXF14_11015	ENOG4108HCJ	Hydrolase
AXF14_11065	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AXF14_11090	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AXF14_11095	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AXF14_11100	ENOG4105KPY	Small multidrug resistance protein
AXF14_11105	ENOG4105FF2	Type I DHQase
AXF14_11110	ENOG4105EMV	Major Facilitator
AXF14_11115	ENOG4105E2X	shikimate dehydrogenase
AXF14_11125	ENOG4105D49	3-dehydroquinate synthase
AXF14_11130	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AXF14_11140	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
AXF14_11165	ENOG4105CBC	glutamate synthase
AXF14_11170	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AXF14_11175	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AXF14_11180	ENOG4105EPD	Oligopeptide transporter, Opt family
AXF14_11190	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AXF14_11205	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
AXF14_11210	ENOG4107QD7	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
AXF14_11215	ENOG4105E5F	proteasome
AXF14_11220	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
AXF14_11235	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AXF14_11245	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AXF14_11250	ENOG4105FDK	ABC transporter
AXF14_11255	ENOG4105FDK	ABC transporter
AXF14_11270	ENOG4105C5H	ABC transporter
AXF14_11290	ENOG4108ZJ4	polysaccharide deacetylase
AXF14_11295	ENOG4105C2C	drug resistance transporter, Bcr CflA
AXF14_11310	ENOG4105CUC	YeeE YedE family protein
AXF14_11320	ENOG4105CPC	Aldo Keto reductase
AXF14_11335	ENOG4105DGW	oligopeptidase A
AXF14_11340	ENOG4105C7K	acetolactate synthase
AXF14_11365	ENOG4105DSB	aldose 1-epimerase
AXF14_11380	ENOG4105C0B	DNA polymerase III (alpha subunit)
AXF14_11385	ENOG4108IQI	permease
AXF14_11400	ENOG4107104	thymidine kinase
AXF14_11420	ENOG4108V1U	phospholipid-binding protein
AXF14_11430	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AXF14_11445	ENOG4107QM5	aconitate hydratase
AXF14_11450	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AXF14_11455	ENOG4105C0X	amino acid
AXF14_11460	ENOG4107VEG	TrkA-N domain protein
AXF14_11505	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXF14_11510	ENOG4105BZW	Glycerate kinase
AXF14_11520	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXF14_11535	ENOG4105DWF	phosphomethylpyrimidine kinase
AXF14_11540	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AXF14_11545	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AXF14_11550	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AXF14_11565	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AXF14_11570	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
AXF14_11610	ENOG4105C5H	ABC transporter
AXF14_11650	ENOG4105DKW	ABC transporter
AXF14_11660	ENOG4107QPH	glycogen) synthase
AXF14_11665	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AXF14_11670	ENOG4105EAC	phosphoserine phosphatase
AXF14_11680	ENOG4105CHR	reductase
AXF14_11700	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AXF14_11715	ENOG4105CC5	ABC transporter
AXF14_11730	ENOG4105C5B	carbamate kinase
AXF14_11735	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AXF14_11740	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
AXF14_11745	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AXF14_11750	ENOG4105C26	Dehydrogenase
AXF14_11760	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AXF14_11770	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AXF14_11780	ENOG4105EHZ	conserved protein UCP016719
AXF14_11790	ENOG4105DFA	alanine racemase domain protein
AXF14_11795	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AXF14_11800	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AXF14_11815	ENOG4105CIG	ABC transporter
AXF14_11820	ENOG4108JJA	ABC, transporter
AXF14_11845	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_11860	ENOG4105BZ1	(ABC) transporter
AXF14_11890	ENOG4105CXY	transporter
AXF14_11930	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AXF14_11940	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AXF14_11960	ENOG4105CRQ	synthase (Component I)
AXF14_11965	ENOG4105RGK	anthranilate synthase component ii
AXF14_11970	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AXF14_11980	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AXF14_11995	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AXF14_12000	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AXF14_12015	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AXF14_12020	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AXF14_12035	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AXF14_12040	ENOG4105EPR	degv family
AXF14_12045	ENOG4105D7A	ATP-binding protein
AXF14_12065	ENOG4105C8T	Leucyl-tRNA synthetase
AXF14_12070	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AXF14_12075	ENOG4107ZUX	Histidine triad (HIT) protein
AXF14_12095	ENOG4105C8J	)-transporter
AXF14_12100	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AXF14_12115	ENOG4108KQ5	Integrase catalytic subunit
AXF14_12125	ENOG4105DFK	Polyphosphate glucokinase
AXF14_12165	ENOG4105F9F	transposase
AXF14_12185	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AXF14_12220	ENOG4105YVS	arsR family transcriptional regulator
AXF14_12225	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AXF14_12235	ENOG4107XZQ	multidrug resistance protein
AXF14_12260	ENOG4107TB6	phosphoglycerate mutase
AXF14_12265	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AXF14_12275	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AXF14_12295	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AXF14_12305	ENOG4105BZ1	(ABC) transporter
AXF14_12325	ENOG4105BZU	Histidine kinase
AXF14_12340	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AXF14_12345	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AXF14_12355	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AXF14_12360	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXF14_12365	ENOG4105K46	50S ribosomal protein l27
AXF14_12370	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AXF14_12380	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AXF14_12385	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AXF14_12395	ENOG4108JJ8	(ABC) transporter
AXF14_12410	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AXF14_12415	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AXF14_12430	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AXF14_12435	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_12440	ENOG4105EDR	glucose galactose transporter
AXF14_12445	ENOG4105NWF	RbsD or FucU transport
AXF14_12450	ENOG4105DET	Rhamnulokinase
AXF14_12460	ENOG4107W7X	Aldolase
AXF14_12470	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AXF14_12475	ENOG4105CB5	ATP-dependent DNA helicase recG
AXF14_12480	ENOG4105DP4	dak2 domain fusion protein ylov
AXF14_12485	ENOG4105VB9	50S ribosomal protein l28
AXF14_12505	ENOG4105ETE	Transcriptional regulator (LacI family
AXF14_12515	ENOG4105CPF	Cell wall formation (By similarity)
AXF14_12530	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AXF14_12540	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AXF14_12545	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AXF14_12565	ENOG4105JNK	Glycosyl transferase (Group 1
AXF14_12570	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AXF14_12580	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AXF14_12600	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AXF14_12610	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AXF14_12620	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AXF14_12625	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AXF14_12645	ENOG4105CKI	cobalamin synthesis protein
AXF14_12650	ENOG4105WH1	Two component transcriptional regulator luxr family
AXF14_12660	ENOG4107R39	(ABC) transporter
AXF14_12685	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AXF14_12690	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AXF14_12705	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXF14_12710	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AXF14_12715	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AXF14_12730	ENOG4105CEP	NADH dehydrogenase
AXF14_12735	ENOG4105CKU	formyltetrahydrofolate synthetase
AXF14_12740	ENOG4105KC9	Modulates RecA activity (By similarity)
AXF14_12745	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AXF14_12755	ENOG4105WBV	Transcriptional regulator
AXF14_12760	ENOG4105CEV	competence damage-inducible protein
AXF14_12770	ENOG4108KQ5	Integrase catalytic subunit
AXF14_12780	ENOG4107QZI	cell division protein FtsK
AXF14_12790	ENOG4105CN5	Metallo-Beta-Lactamase
AXF14_12815	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AXF14_12820	ENOG4105C87	Aminotransferase class I and II
AXF14_12825	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AXF14_12865	ENOG4108J5H	Homocysteine s-methyltransferase
AXF14_12870	ENOG4108IQI	permease
AXF14_12875	ENOG4108Z66	YbaK ebsC protein
AXF14_12885	ENOG410901E	Membrane
AXF14_12925	ENOG4108KQ5	Integrase catalytic subunit