locus-tag	class	description
AXF14_00005	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_00055	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AXF14_00060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXF14_00085	COG1234	tRNA 3'-trailer cleavage
AXF14_00100	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXF14_00120	COG0363	glucosamine-6-phosphate deaminase activity
AXF14_00145	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AXF14_00155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXF14_00160	COG4608	Belongs to the ABC transporter superfamily
AXF14_00165	COG0444	Belongs to the ABC transporter superfamily
AXF14_00175	COG0747	negative chemotaxis
AXF14_00180	COG2186	Transcriptional regulator
AXF14_00185	COG2233	PERMEase
AXF14_00200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXF14_00210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXF14_00235	COG0739	heme binding
AXF14_00240	COG2177	Part of the ABC transporter FtsEX involved in
AXF14_00245	COG2884	Cell division ATP-binding protein ftsE
AXF14_00270	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_00295	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AXF14_00315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXF14_00320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXF14_00325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXF14_00350	COG0473	3-isopropylmalate dehydrogenase activity
AXF14_00355	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AXF14_00360	COG0440	acetolactate synthase activity
AXF14_00370	COG0569	domain protein
AXF14_00370	COG2985	domain, Protein
AXF14_00410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXF14_00415	COG0154	amidase activity
AXF14_00420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXF14_00440	COG1674	ftsk spoiiie
AXF14_00470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AXF14_00490	COG1174	glycine betaine transport
AXF14_00495	COG1174	glycine betaine transport
AXF14_00500	COG1125	glycine betaine transport
AXF14_00500	COG0517	IMP dehydrogenase activity
AXF14_00515	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_00535	COG1064	alcohol dehydrogenase
AXF14_00560	COG0114	fumarate hydratase activity
AXF14_00565	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AXF14_00605	COG0406	alpha-ribazole phosphatase activity
AXF14_00605	COG0328	RNA-DNA hybrid ribonuclease activity
AXF14_00640	COG1473	amidohydrolase
AXF14_00655	COG0714	Associated with various cellular activities
AXF14_00695	COG4555	ABC transporter
AXF14_00720	COG1028	Short-chain dehydrogenase reductase Sdr
AXF14_00720	COG0604	alcohol dehydrogenase
AXF14_00720	COG3321	synthase
AXF14_00735	COG1615	UPF0182 protein
AXF14_00785	COG0482	sulfurtransferase activity
AXF14_00800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AXF14_00805	COG2086	electron transfer activity
AXF14_00815	COG0180	Tryptophanyl-tRNA synthetase
AXF14_00820	COG0366	Alpha amylase catalytic
AXF14_00830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXF14_00835	COG0058	SHG alpha-glucan phosphorylase activity
AXF14_00860	COG1725	Transcriptional regulator
AXF14_00875	COG3833	ABC-type maltose transport systems, permease component
AXF14_00890	COG0039	L-malate dehydrogenase activity
AXF14_00935	COG0045	succinate-CoA ligase (ADP-forming) activity
AXF14_00940	COG0205	6-phosphofructokinase activity
AXF14_00955	COG1012	belongs to the aldehyde dehydrogenase family
AXF14_00965	COG1175	transmembrane transport
AXF14_00970	COG1653	transport
AXF14_00980	COG3415	Transposase
AXF14_00980	COG2801	Transposase and inactivated derivatives
AXF14_00985	COG1501	Belongs to the glycosyl hydrolase 31 family
AXF14_00990	COG1028	Short-chain dehydrogenase reductase Sdr
AXF14_00995	COG1609	Transcriptional regulator
AXF14_01000	COG0366	Alpha amylase catalytic
AXF14_01015	COG1653	transport
AXF14_01020	COG1472	Belongs to the glycosyl hydrolase 3 family
AXF14_01070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AXF14_01075	COG0254	rRNA binding
AXF14_01090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXF14_01100	COG0083	homoserine kinase activity
AXF14_01105	COG0460	homoserine dehydrogenase
AXF14_01115	COG1122	ATPase activity
AXF14_01130	COG3415	Transposase
AXF14_01130	COG2801	Transposase and inactivated derivatives
AXF14_01150	COG0019	diaminopimelate decarboxylase activity
AXF14_01155	COG0018	arginyl-trna synthetase
AXF14_01170	COG0584	glycerophosphoryl diester phosphodiesterase
AXF14_01175	COG0739	heme binding
AXF14_01190	COG0567	Dehydrogenase, E1 component
AXF14_01190	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXF14_01205	COG5662	AntiSigma factor
AXF14_01210	COG1595	DNA-templated transcription, initiation
AXF14_01235	COG2838	Isocitrate dehydrogenase
AXF14_01240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXF14_01245	COG1162	GTPase activity
AXF14_01275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXF14_01295	COG0315	cyclic pyranopterin monophosphate synthase activity
AXF14_01305	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXF14_01305	COG0315	cyclic pyranopterin monophosphate synthase activity
AXF14_01320	COG1140	nitrate reductase beta subunit
AXF14_01345	COG1063	alcohol dehydrogenase
AXF14_01350	COG3415	Transposase
AXF14_01350	COG2801	Transposase and inactivated derivatives
AXF14_01355	COG1028	Short-chain dehydrogenase reductase Sdr
AXF14_01375	COG0483	inositol monophosphate 1-phosphatase activity
AXF14_01380	COG1968	undecaprenyl-diphosphatase activity
AXF14_01385	COG0420	3'-5' exonuclease activity
AXF14_01390	COG0419	ATPase involved in DNA repair
AXF14_01430	COG0653	protein targeting
AXF14_01435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXF14_01440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXF14_01445	COG5401	PFAM Sporulation and spore germination
AXF14_01450	COG5000	phosphorelay sensor kinase activity
AXF14_01450	COG5002	protein histidine kinase activity
AXF14_01455	COG0745	RESPONSE REGULATOR receiver
AXF14_01475	COG0714	Associated with various cellular activities
AXF14_01480	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AXF14_01530	COG1482	cell wall glycoprotein biosynthetic process
AXF14_01540	COG4750	Nucleotidyl transferase
AXF14_01545	COG0697	spore germination
AXF14_01550	COG3475	LICD family
AXF14_01565	COG1216	Glycosyl transferase, family 2
AXF14_01570	COG3475	LICD family
AXF14_01620	COG0438	transferase activity, transferring glycosyl groups
AXF14_01630	COG0438	transferase activity, transferring glycosyl groups
AXF14_01630	COG1216	Glycosyl transferase, family 2
AXF14_01655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXF14_01665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AXF14_01680	COG0438	transferase activity, transferring glycosyl groups
AXF14_01725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXF14_01745	COG1316	TRANSCRIPTIONal
AXF14_01750	COG1316	TRANSCRIPTIONal
AXF14_01755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXF14_01760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXF14_01785	COG5002	protein histidine kinase activity
AXF14_01790	COG0745	RESPONSE REGULATOR receiver
AXF14_01805	COG0424	maF-like protein
AXF14_01810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXF14_01825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXF14_01845	COG1666	GTP binding
AXF14_01850	COG0501	Belongs to the peptidase M48B family
AXF14_01855	COG0456	acetyltransferase
AXF14_01855	COG0454	-acetyltransferase
AXF14_01880	COG1007	ATP synthesis coupled electron transport
AXF14_01890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXF14_01895	COG0713	ATP synthesis coupled electron transport
AXF14_01905	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXF14_01910	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AXF14_01915	COG1034	ATP synthesis coupled electron transport
AXF14_01920	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXF14_01930	COG0649	NAD binding
AXF14_01935	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXF14_01940	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXF14_01955	COG2226	methyltransferase
AXF14_01965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXF14_01975	COG2801	Transposase and inactivated derivatives
AXF14_02030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AXF14_02035	COG4948	Mandelate Racemase Muconate Lactonizing
AXF14_02040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AXF14_02095	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AXF14_02095	COG0028	Belongs to the TPP enzyme family
AXF14_02100	COG1012	belongs to the aldehyde dehydrogenase family
AXF14_02140	COG2235	arginine
AXF14_02160	COG2197	response regulator
AXF14_02165	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXF14_02190	COG3477	response to acidic pH
AXF14_02215	COG0406	alpha-ribazole phosphatase activity
AXF14_02220	COG2171	N-acyltransferase activity
AXF14_02230	COG1053	succinate dehydrogenase
AXF14_02290	COG0747	negative chemotaxis
AXF14_02300	COG0747	negative chemotaxis
AXF14_02325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXF14_02330	COG0601	transmembrane transport
AXF14_02335	COG0747	negative chemotaxis
AXF14_02340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXF14_02345	COG0385	Bile acid
AXF14_02370	COG2514	catechol 2,3-dioxygenase activity
AXF14_02375	COG4667	esterase of the alpha-beta hydrolase superfamily
AXF14_02380	COG1902	pentaerythritol trinitrate reductase activity
AXF14_02385	COG3012	SEC-C Motif Domain Protein
AXF14_02390	COG1362	aminopeptidase activity
AXF14_02440	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_02480	COG0789	Transcriptional regulator
AXF14_02540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXF14_02555	COG1278	Cold shock
AXF14_02605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXF14_02615	COG0656	L-ascorbic acid biosynthetic process
AXF14_02620	COG1090	epimerase
AXF14_02625	COG0436	Aminotransferase
AXF14_02640	COG0012	GTP binding
AXF14_02665	COG1322	Protein conserved in bacteria
AXF14_02675	COG1570	exodeoxyribonuclease VII activity
AXF14_02680	COG1609	Transcriptional regulator
AXF14_02690	COG1621	beta-fructofuranosidase activity
AXF14_02695	COG1722	exodeoxyribonuclease VII activity
AXF14_02705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXF14_02720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXF14_02745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXF14_02755	COG1279	arginine transmembrane transporter activity
AXF14_02760	COG0583	DNA-binding transcription factor activity
AXF14_02780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXF14_02785	COG0129	dihydroxy-acid dehydratase activity
AXF14_02815	COG2197	response regulator
AXF14_02820	COG0193	aminoacyl-tRNA hydrolase activity
AXF14_02825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AXF14_02855	COG0148	phosphopyruvate hydratase activity
AXF14_02885	COG2801	Transposase and inactivated derivatives
AXF14_02885	COG3415	Transposase
AXF14_02890	COG2244	polysaccharide biosynthetic process
AXF14_02950	COG0297	glycogen (starch) synthase activity
AXF14_02960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXF14_02975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXF14_02985	COG1309	transcriptional regulator
AXF14_02995	COG0488	(ABC) transporter
AXF14_03000	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AXF14_03005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXF14_03025	COG0084	hydrolase, TatD family'
AXF14_03030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXF14_03045	COG1335	isochorismatase
AXF14_03095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXF14_03105	COG1970	mechanosensitive ion channel activity
AXF14_03155	COG2252	PERMEase
AXF14_03160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXF14_03180	COG1061	Type III restriction enzyme res subunit
AXF14_03215	COG0745	RESPONSE REGULATOR receiver
AXF14_03220	COG2205	protein histidine kinase activity
AXF14_03235	COG0459	protein refolding
AXF14_03250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AXF14_03275	COG3842	ATPase activity
AXF14_03295	COG0215	cysteine-tRNA ligase activity
AXF14_03300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXF14_03305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXF14_03315	COG2801	Transposase and inactivated derivatives
AXF14_03315	COG3415	Transposase
AXF14_03340	COG3716	PTS system mannose fructose sorbose family IID component
AXF14_03345	COG3715	PTS system
AXF14_03350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXF14_03350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXF14_03360	COG0561	phosphatase activity
AXF14_03375	COG1621	beta-fructofuranosidase activity
AXF14_03390	COG2272	Belongs to the type-B carboxylesterase lipase family
AXF14_03410	COG0577	efflux transmembrane transporter activity
AXF14_03430	COG0745	RESPONSE REGULATOR receiver
AXF14_03435	COG2205	protein histidine kinase activity
AXF14_03440	COG0789	Transcriptional regulator
AXF14_03455	COG2353	YceI-like domain
AXF14_03460	COG1505	serine-type exopeptidase activity
AXF14_03475	COG0789	Transcriptional regulator
AXF14_03480	COG0484	heat shock protein binding
AXF14_03495	COG0443	Heat shock 70 kDa protein
AXF14_03505	COG1136	(ABC) transporter
AXF14_03505	COG0577	efflux transmembrane transporter activity
AXF14_03565	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_03590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXF14_03600	COG1131	(ABC) transporter
AXF14_03690	COG0778	Nitroreductase
AXF14_03710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AXF14_03715	COG0738	Major facilitator superfamily
AXF14_03725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXF14_03735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AXF14_03745	COG0471	metal ion transport
AXF14_03750	COG1569	PIN domain
AXF14_03755	COG3311	Transcriptional regulator
AXF14_03780	COG1111	helicase
AXF14_03780	COG1205	dead DEAH box helicase
AXF14_03810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXF14_03875	COG0601	transmembrane transport
AXF14_03910	COG3842	ATPase activity
AXF14_03935	COG2181	nitrate reductase activity
AXF14_03935	COG0247	lactate metabolic process
AXF14_03945	COG2364	Membrane
AXF14_03960	COG2382	esterase
AXF14_03965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AXF14_03970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXF14_03980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXF14_03990	COG3386	PFAM SMP-30 Gluconolaconase
AXF14_04010	COG2274	protein secretion by the type I secretion system
AXF14_04015	COG1132	(ABC) transporter
AXF14_04025	COG0626	cystathionine gamma-synthase activity
AXF14_04040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXF14_04065	COG0471	metal ion transport
AXF14_04085	COG0561	phosphatase activity
AXF14_04090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXF14_04100	COG1597	lipid kinase activity
AXF14_04155	COG2814	Major facilitator Superfamily
AXF14_04175	COG0534	Mate efflux family protein
AXF14_04200	COG3588	fructose-bisphosphate aldolase
AXF14_04215	COG1028	Short-chain dehydrogenase reductase Sdr
AXF14_04245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXF14_04250	COG1950	PFAM Membrane protein of
AXF14_04265	COG3559	Exporter of polyketide antibiotics
AXF14_04270	COG1131	(ABC) transporter
AXF14_04280	COG2813	Specifically methylates the guanine in position
AXF14_04285	COG3579	cysteine-type endopeptidase activity
AXF14_04300	COG1937	Protein conserved in bacteria
AXF14_04320	COG2801	Transposase and inactivated derivatives
AXF14_04320	COG3415	Transposase
AXF14_04330	COG1215	transferase activity, transferring glycosyl groups
AXF14_04365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXF14_04370	COG1454	alcohol dehydrogenase
AXF14_04380	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXF14_04395	COG0483	inositol monophosphate 1-phosphatase activity
AXF14_04400	COG1063	alcohol dehydrogenase
AXF14_04405	COG0156	8-amino-7-oxononanoate synthase activity
AXF14_04420	COG1113	amino acid transport
AXF14_04430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXF14_04435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXF14_04440	COG1940	carbohydrate kinase activity
AXF14_04445	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AXF14_04465	COG2197	response regulator
AXF14_04480	COG2197	response regulator
AXF14_04495	COG1854	S-ribosylhomocysteine lyase activity
AXF14_04550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXF14_04560	COG2985	domain, Protein
AXF14_04560	COG0569	domain protein
AXF14_04565	COG1428	Deoxynucleoside kinase
AXF14_04575	COG1966	Carbon starvation protein
AXF14_04600	COG1716	ATPase activity
AXF14_04605	COG1716	ATPase activity
AXF14_04620	COG0768	penicillin binding
AXF14_04625	COG0515	serine threonine protein kinase
AXF14_04630	COG0515	serine threonine protein kinase
AXF14_04635	COG3764	Sortase (surface protein transpeptidase)
AXF14_04645	COG0656	L-ascorbic acid biosynthetic process
AXF14_04680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXF14_04685	COG0187	DNA topoisomerase II activity
AXF14_04690	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AXF14_04695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AXF14_04700	COG0592	DNA-directed DNA polymerase activity
AXF14_04705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXF14_04710	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AXF14_04715	COG0594	ribonuclease P activity
AXF14_04720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AXF14_04725	COG0706	membrane insertase activity
AXF14_04735	COG0357	Ribosomal RNA small subunit methyltransferase G
AXF14_04740	COG1192	Involved in chromosome partitioning
AXF14_04755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXF14_04760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXF14_04765	COG0110	maltose O-acetyltransferase activity
AXF14_04770	COG3118	belongs to the thioredoxin family
AXF14_04795	COG0617	tRNA 3'-terminal CCA addition
AXF14_04800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AXF14_04805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXF14_04820	COG0789	Transcriptional regulator
AXF14_04835	COG0360	Binds together with S18 to 16S ribosomal RNA
AXF14_04840	COG0629	single-stranded DNA binding
AXF14_04845	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXF14_04850	COG0359	binds to the 23S rRNA
AXF14_04860	COG0305	Participates in initiation and elongation during chromosome replication
AXF14_04865	COG0351	phosphomethylpyrimidine kinase
AXF14_04880	COG1760	l-serine dehydratase
AXF14_04890	COG3550	peptidyl-serine autophosphorylation
AXF14_04905	COG4115	mRNA cleavage
AXF14_04910	COG2161	toxin-antitoxin pair type II binding
AXF14_04965	COG2197	response regulator
AXF14_04990	COG1780	Probably involved in ribonucleotide reductase function
AXF14_04995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXF14_05015	COG3527	Alpha-acetolactate decarboxylase
AXF14_05030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXF14_05040	COG1737	Transcriptional regulator
AXF14_05045	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AXF14_05060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXF14_05085	COG0798	PFAM Bile acid sodium symporter
AXF14_05090	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXF14_05135	COG1404	Belongs to the peptidase S8 family
AXF14_05150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXF14_05155	COG2011	ABC-type metal ion transport system permease component
AXF14_05165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXF14_05170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXF14_05175	COG0590	tRNA wobble adenosine to inosine editing
AXF14_05180	COG0110	maltose O-acetyltransferase activity
AXF14_05210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXF14_05215	COG1643	Atp-dependent helicase
AXF14_05260	COG2233	PERMEase
AXF14_05295	COG2376	Dihydroxyacetone kinase
AXF14_05300	COG1461	Dihydroxyacetone kinase
AXF14_05305	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AXF14_05305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXF14_05305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXF14_05335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AXF14_05365	COG0738	Major facilitator superfamily
AXF14_05370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXF14_05385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AXF14_05390	COG0113	porphobilinogen synthase activity
AXF14_05410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AXF14_05445	COG1051	belongs to the nudix hydrolase family
AXF14_05460	COG1597	lipid kinase activity
AXF14_05470	COG1408	metallophosphoesterase
AXF14_05475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXF14_05485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXF14_05505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXF14_05575	COG0450	alkyl hydroperoxide reductase
AXF14_05590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXF14_05610	COG2890	protein-(glutamine-N5) methyltransferase activity
AXF14_05635	COG2205	protein histidine kinase activity
AXF14_05640	COG3415	Transposase
AXF14_05640	COG2801	Transposase and inactivated derivatives
AXF14_05645	COG0745	RESPONSE REGULATOR receiver
AXF14_05655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AXF14_05665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXF14_05665	COG1754	DNA topoisomerase type I activity
AXF14_05675	COG0470	DNA polymerase III
AXF14_05685	COG0252	asparaginase activity
AXF14_05690	COG1113	amino acid transport
AXF14_05710	COG0704	Plays a role in the regulation of phosphate uptake
AXF14_05720	COG0745	RESPONSE REGULATOR receiver
AXF14_05735	COG1764	response to oxidative stress
AXF14_05745	COG0494	nUDIX hydrolase
AXF14_05755	COG1070	Carbohydrate kinase
AXF14_05775	COG1121	(ABC) transporter
AXF14_05785	COG0393	Putative heavy-metal-binding
AXF14_05800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXF14_05810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXF14_05815	COG1643	Atp-dependent helicase
AXF14_05840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXF14_05845	COG3142	Participates in the control of copper homeostasis
AXF14_05860	COG1132	(ABC) transporter
AXF14_05865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AXF14_05870	COG2860	membrane
AXF14_05950	COG2003	Belongs to the UPF0758 family
AXF14_05955	COG0714	Associated with various cellular activities
AXF14_06035	COG0717	Belongs to the dCTP deaminase family
AXF14_06045	COG2176	DNA-directed DNA polymerase activity
AXF14_06050	COG0778	Nitroreductase
AXF14_06070	COG4221	oxidoreductase activity
AXF14_06075	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AXF14_06085	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AXF14_06100	COG0785	Cytochrome C biogenesis protein
AXF14_06105	COG1333	cytochrome c biogenesis protein
AXF14_06110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXF14_06120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AXF14_06135	COG0191	fructose-bisphosphate aldolase activity
AXF14_06165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AXF14_06170	COG0672	)-iron permease
AXF14_06195	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AXF14_06215	COG0151	Belongs to the GarS family
AXF14_06220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AXF14_06240	COG0047	phosphoribosylformylglycinamidine synthase activity
AXF14_06245	COG0438	transferase activity, transferring glycosyl groups
AXF14_06250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXF14_06260	COG0492	ferredoxin-NADP+ reductase activity
AXF14_06270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXF14_06275	COG4085	toxin activity
AXF14_06275	COG1525	nuclease
AXF14_06275	COG0737	Belongs to the 5'-nucleotidase family
AXF14_06300	COG0557	exoribonuclease II activity
AXF14_06305	COG2186	Transcriptional regulator
AXF14_06315	COG2084	Dehydrogenase
AXF14_06320	COG2610	gluconate transmembrane transporter activity
AXF14_06330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AXF14_06385	COG1132	(ABC) transporter
AXF14_06400	COG1472	Belongs to the glycosyl hydrolase 3 family
AXF14_06430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXF14_06455	COG3265	gluconokinase activity
AXF14_06465	COG0513	Belongs to the DEAD box helicase family
AXF14_06520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXF14_06545	COG0745	RESPONSE REGULATOR receiver
AXF14_06560	COG3485	protocatechuate 3,4-dioxygenase
AXF14_06565	COG0354	folic acid binding
AXF14_06575	COG1490	D-aminoacyl-tRNA deacylase activity
AXF14_06595	COG2197	response regulator
AXF14_06630	COG0604	alcohol dehydrogenase
AXF14_06635	COG1846	Transcriptional regulator
AXF14_06645	COG0477	Major facilitator Superfamily
AXF14_06655	COG2197	response regulator
AXF14_06670	COG2211	Major facilitator Superfamily
AXF14_06685	COG0574	Belongs to the PEP-utilizing enzyme family
AXF14_06685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXF14_06690	COG0714	Associated with various cellular activities
AXF14_06705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AXF14_06710	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AXF14_06720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXF14_06725	COG2873	o-acetylhomoserine
AXF14_06735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXF14_06740	COG2027	D-alanyl-D-alanine carboxypeptidase
AXF14_06760	COG0302	gtp cyclohydrolase
AXF14_06765	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AXF14_06770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXF14_06800	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AXF14_06805	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AXF14_06820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AXF14_06870	COG1556	Lactate utilization protein
AXF14_06880	COG0247	lactate metabolic process
AXF14_06885	COG1620	l-lactate permease
AXF14_06890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXF14_06895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXF14_06915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXF14_06925	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AXF14_06940	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AXF14_06950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXF14_06955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXF14_06965	COG2814	Major facilitator Superfamily
AXF14_06975	COG2390	Transcriptional regulator
AXF14_06985	COG2376	Dihydroxyacetone kinase
AXF14_06990	COG2376	Dihydroxyacetone kinase
AXF14_07005	COG3775	system Galactitol-specific IIC component
AXF14_07045	COG2017	converts alpha-aldose to the beta-anomer
AXF14_07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXF14_07080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AXF14_07090	COG1115	amino acid carrier protein
AXF14_07095	COG0436	Aminotransferase
AXF14_07110	COG0250	Participates in transcription elongation, termination and antitermination
AXF14_07115	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AXF14_07120	COG0081	regulation of translation
AXF14_07135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXF14_07140	COG0222	ribosome binding
AXF14_07145	COG0085	RNA polymerase activity
AXF14_07150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXF14_07155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXF14_07160	COG0049	tRNA binding
AXF14_07165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXF14_07170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXF14_07175	COG0051	transcription antitermination factor activity, RNA binding
AXF14_07180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AXF14_07185	COG0088	Forms part of the polypeptide exit tunnel
AXF14_07190	COG0089	rRNA binding
AXF14_07195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXF14_07200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXF14_07205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AXF14_07210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AXF14_07215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXF14_07220	COG0255	Belongs to the universal ribosomal protein uL29 family
AXF14_07225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXF14_07230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AXF14_07235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AXF14_07240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXF14_07245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXF14_07255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AXF14_07265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXF14_07270	COG1841	ribosomal large subunit assembly
AXF14_07275	COG0200	Binds to the 23S rRNA
AXF14_07285	COG0563	adenylate kinase activity
AXF14_07295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXF14_07300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXF14_07305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXF14_07310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXF14_07315	COG0202	RNA polymerase activity
AXF14_07320	COG0203	ribosomal protein L17
AXF14_07335	COG0101	tRNA pseudouridine synthase activity
AXF14_07340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXF14_07355	COG1072	(Pantothenic acid kinase))
AXF14_07360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXF14_07375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXF14_07380	COG0802	atpase or kinase
AXF14_07405	COG1053	succinate dehydrogenase
AXF14_07410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXF14_07415	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AXF14_07420	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AXF14_07435	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXF14_07455	COG0516	GMP reductase activity
AXF14_07460	COG1175	transmembrane transport
AXF14_07465	COG0395	ABC-type sugar transport system, permease component
AXF14_07475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXF14_07480	COG2095	MarC family integral membrane protein
AXF14_07490	COG4975	Glucose uptake
AXF14_07495	COG1733	regulation of RNA biosynthetic process
AXF14_07510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXF14_07520	COG1609	Transcriptional regulator
AXF14_07525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXF14_07525	COG0519	Catalyzes the synthesis of GMP from XMP
AXF14_07570	COG2409	Drug exporters of the RND superfamily
AXF14_07580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXF14_07620	COG0577	efflux transmembrane transporter activity
AXF14_07620	COG1136	(ABC) transporter
AXF14_07625	COG0693	protein deglycase activity
AXF14_07630	COG0656	L-ascorbic acid biosynthetic process
AXF14_07655	COG2197	response regulator
AXF14_07670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXF14_07680	COG0356	it plays a direct role in the translocation of protons across the membrane
AXF14_07685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AXF14_07690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXF14_07695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AXF14_07700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AXF14_07705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AXF14_07710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AXF14_07715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AXF14_07725	COG1028	Short-chain dehydrogenase reductase Sdr
AXF14_07735	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AXF14_07745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AXF14_07780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXF14_07785	COG0254	rRNA binding
AXF14_07790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXF14_07795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXF14_07800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXF14_07810	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AXF14_07815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AXF14_07830	COG1254	Belongs to the acylphosphatase family
AXF14_07835	COG5492	domain, Protein
AXF14_07835	COG1621	beta-fructofuranosidase activity
AXF14_07835	COG3583	domain protein
AXF14_07840	COG1621	beta-fructofuranosidase activity
AXF14_07860	COG1136	(ABC) transporter
AXF14_07860	COG0577	efflux transmembrane transporter activity
AXF14_07865	COG0577	efflux transmembrane transporter activity
AXF14_07865	COG1136	(ABC) transporter
AXF14_07875	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXF14_07880	COG1609	Transcriptional regulator
AXF14_07890	COG2211	Major facilitator Superfamily
AXF14_07915	COG1744	ABC transporter substrate-binding protein PnrA-like
AXF14_07945	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXF14_07950	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AXF14_07960	COG1121	(ABC) transporter
AXF14_07980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXF14_08005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AXF14_08020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXF14_08025	COG1611	Belongs to the LOG family
AXF14_08040	COG2151	metal-sulfur cluster biosynthetic enzyme
AXF14_08040	COG0489	protein tyrosine kinase activity
AXF14_08055	COG2239	Acts as a magnesium transporter
AXF14_08065	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_08070	COG1082	Xylose isomerase domain protein TIM barrel
AXF14_08090	COG0006	proline dipeptidase activity
AXF14_08105	COG2095	MarC family integral membrane protein
AXF14_08150	COG3415	Transposase
AXF14_08150	COG2801	Transposase and inactivated derivatives
AXF14_08155	COG3415	Transposase
AXF14_08155	COG2801	Transposase and inactivated derivatives
AXF14_08160	COG0513	Belongs to the DEAD box helicase family
AXF14_08175	COG0473	3-isopropylmalate dehydrogenase activity
AXF14_08180	COG4948	Mandelate Racemase Muconate Lactonizing
AXF14_08270	COG0583	DNA-binding transcription factor activity
AXF14_08275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AXF14_08290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXF14_08305	COG2190	(PTS) system
AXF14_08315	COG2188	Transcriptional regulator
AXF14_08320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXF14_08320	COG1263	PTS System
AXF14_08335	COG3590	peptidase
AXF14_08360	COG1045	serine acetyltransferase
AXF14_08370	COG1739	Uncharacterized protein family UPF0029
AXF14_08395	COG0544	peptidyl-prolyl cis-trans isomerase activity
AXF14_08410	COG0740	serine-type endopeptidase activity
AXF14_08415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AXF14_08420	COG1605	Chorismate mutase
AXF14_08420	COG0287	Prephenate dehydrogenase
AXF14_08465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXF14_08500	COG0366	Alpha amylase catalytic
AXF14_08505	COG2190	(PTS) system
AXF14_08505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXF14_08505	COG1263	PTS System
AXF14_08520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXF14_08520	COG1648	precorrin-2 dehydrogenase activity
AXF14_08540	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXF14_08545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXF14_08565	COG0285	dihydrofolate synthase activity
AXF14_08580	COG1461	Dihydroxyacetone kinase
AXF14_08585	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AXF14_08590	COG0105	UTP biosynthetic process
AXF14_08605	COG1196	nuclear chromosome segregation
AXF14_08635	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AXF14_08660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXF14_08670	COG1837	Belongs to the UPF0109 family
AXF14_08675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXF14_08680	COG0336	Belongs to the RNA methyltransferase TrmD family
AXF14_08695	COG0681	Belongs to the peptidase S26 family
AXF14_08700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXF14_08715	COG0606	chelatase, subunit chli
AXF14_08735	COG0052	Belongs to the universal ribosomal protein uS2 family
AXF14_08740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AXF14_08755	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_08760	COG0233	cytoplasmic translational termination
AXF14_08770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXF14_08780	COG0750	zinc metalloprotease
AXF14_08795	COG3425	synthase
AXF14_08835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXF14_08840	COG0442	prolyl-tRNA aminoacylation
AXF14_08850	COG0779	Required for maturation of 30S ribosomal subunits
AXF14_08855	COG0195	Participates in both transcription termination and antitermination
AXF14_08865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AXF14_08890	COG2962	Rard protein
AXF14_08900	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXF14_08910	COG0196	riboflavin kinase activity
AXF14_08920	COG1185	polyribonucleotide nucleotidyltransferase activity
AXF14_08925	COG0612	Peptidase, M16
AXF14_08940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AXF14_08950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXF14_08955	COG0318	PFAM AMP-dependent synthetase and ligase
AXF14_08975	COG2271	Major facilitator Superfamily
AXF14_08995	COG2001	Belongs to the MraZ family
AXF14_09000	COG0275	rRNA processing
AXF14_09015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXF14_09020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXF14_09025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXF14_09030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AXF14_09035	COG0772	Belongs to the SEDS family
AXF14_09045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXF14_09055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXF14_09065	COG1799	cell septum assembly
AXF14_09075	COG3599	regulation of cell shape
AXF14_09100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXF14_09105	COG0587	DNA-directed DNA polymerase activity
AXF14_09120	COG2501	S4 domain
AXF14_09165	COG0732	type I restriction modification DNA specificity domain
AXF14_09205	COG4139	cobalamin transport
AXF14_09210	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AXF14_09245	COG0598	Magnesium transport protein CorA
AXF14_09250	COG0514	ATP-dependent DNA helicase (RecQ)
AXF14_09285	COG1070	Carbohydrate kinase
AXF14_09295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXF14_09300	COG3775	system Galactitol-specific IIC component
AXF14_09305	COG0025	NhaP-type Na H and K H
AXF14_09320	COG0131	Imidazoleglycerol-phosphate dehydratase
AXF14_09330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXF14_09335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AXF14_09345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AXF14_09350	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AXF14_09355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AXF14_09365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXF14_09370	COG1175	transmembrane transport
AXF14_09375	COG0395	ABC-type sugar transport system, permease component
AXF14_09380	COG1653	transport
AXF14_09395	COG1486	melibiose metabolic process
AXF14_09400	COG1126	abc transporter atp-binding protein
AXF14_09405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXF14_09410	COG0765	amino acid transport
AXF14_09415	COG0765	amino acid transport
AXF14_09420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AXF14_09425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXF14_09425	COG0072	phenylalanine-tRNA ligase activity
AXF14_09440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AXF14_09450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXF14_09455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXF14_09460	COG1438	arginine binding
AXF14_09465	COG0137	argininosuccinate synthase activity
AXF14_09475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXF14_09485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXF14_09525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AXF14_09530	COG0497	DNA recombination
AXF14_09560	COG0504	CTP synthase activity
AXF14_09580	COG1175	transmembrane transport
AXF14_09585	COG0395	ABC-type sugar transport system, permease component
AXF14_09605	COG0719	Fe-S assembly protein
AXF14_09615	COG0396	ATPase activity
AXF14_09625	COG0822	iron-sulfur transferase activity
AXF14_09630	COG2151	metal-sulfur cluster biosynthetic enzyme
AXF14_09650	COG3189	MarR family transcriptional regulator
AXF14_09660	COG0167	dihydroorotate dehydrogenase activity
AXF14_09675	COG0667	Aldo Keto reductase
AXF14_09685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXF14_09695	COG1609	Transcriptional regulator
AXF14_09700	COG0366	Alpha amylase catalytic
AXF14_09705	COG3833	ABC-type maltose transport systems, permease component
AXF14_09710	COG1175	transmembrane transport
AXF14_09715	COG2182	Extracellular solute-binding protein
AXF14_09730	COG0358	DNA primase activity
AXF14_09765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXF14_09770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXF14_09790	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AXF14_09805	COG0384	phenazine biosynthesis protein PhzF
AXF14_09815	COG2197	response regulator
AXF14_09820	COG4585	Histidine kinase
AXF14_09825	COG1131	(ABC) transporter
AXF14_09845	COG0596	Alpha beta hydrolase
AXF14_09845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXF14_09845	COG2226	methyltransferase
AXF14_09855	COG5504	Zn-dependent protease
AXF14_09880	COG0436	Aminotransferase
AXF14_09895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXF14_09905	COG3022	response to hydroperoxide
AXF14_09935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AXF14_09940	COG0174	glutamine synthetase
AXF14_09945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXF14_09955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXF14_09965	COG0765	amino acid transport
AXF14_09970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXF14_09980	COG0174	glutamine synthetase
AXF14_09990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXF14_09995	COG0321	lipoyl(octanoyl) transferase activity
AXF14_10000	COG0515	serine threonine protein kinase
AXF14_10005	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXF14_10010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXF14_10015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXF14_10025	COG0038	chloride channel
AXF14_10035	COG1882	Formate acetyltransferase
AXF14_10110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXF14_10125	COG1560	Kdo2-lipid A biosynthetic process
AXF14_10130	COG0438	transferase activity, transferring glycosyl groups
AXF14_10145	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AXF14_10150	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AXF14_10155	COG0494	nUDIX hydrolase
AXF14_10160	COG0217	transcriptional regulatory protein
AXF14_10165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AXF14_10170	COG0632	four-way junction helicase activity
AXF14_10175	COG2255	four-way junction helicase activity
AXF14_10185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXF14_10190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXF14_10195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXF14_10200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXF14_10215	COG1305	Transglutaminase-like
AXF14_10235	COG1305	Transglutaminase-like
AXF14_10240	COG3383	formate dehydrogenase (NAD+) activity
AXF14_10240	COG0243	molybdopterin cofactor binding
AXF14_10245	COG0437	4 iron, 4 sulfur cluster binding
AXF14_10260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXF14_10265	COG0488	(ABC) transporter
AXF14_10290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXF14_10310	COG2826	transposase and inactivated derivatives, IS30 family
AXF14_10350	COG2826	transposase and inactivated derivatives, IS30 family
AXF14_10360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXF14_10360	COG1116	anion transmembrane transporter activity
AXF14_10385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AXF14_10395	COG0009	L-threonylcarbamoyladenylate synthase
AXF14_10405	COG2409	Drug exporters of the RND superfamily
AXF14_10415	COG0730	response to heat
AXF14_10420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXF14_10425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXF14_10430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXF14_10440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXF14_10445	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AXF14_10450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AXF14_10460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AXF14_10470	COG0702	epimerase
AXF14_10475	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AXF14_10480	COG0540	Belongs to the ATCase OTCase family
AXF14_10485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXF14_10495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AXF14_10500	COG0284	orotidine-5'-phosphate decarboxylase activity
AXF14_10505	COG0194	GDP metabolic process
AXF14_10510	COG0194	GDP metabolic process
AXF14_10515	COG1758	RNA polymerase activity
AXF14_10525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXF14_10530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AXF14_10540	COG4716	Myosin-crossreactive antigen
AXF14_10550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXF14_10560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXF14_10570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXF14_10580	COG4770	biotin carboxylase activity
AXF14_10585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXF14_10590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXF14_10620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXF14_10625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXF14_10630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXF14_10635	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AXF14_10640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXF14_10645	COG0140	phosphoribosyl-ATP diphosphatase activity
AXF14_10660	COG2197	response regulator
AXF14_10665	COG4585	Histidine kinase
AXF14_10685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXF14_10705	COG2354	Protein conserved in bacteria
AXF14_10715	COG1216	Glycosyl transferase, family 2
AXF14_10725	COG0205	6-phosphofructokinase activity
AXF14_10735	COG0604	alcohol dehydrogenase
AXF14_10745	COG0577	efflux transmembrane transporter activity
AXF14_10750	COG1136	(ABC) transporter
AXF14_10760	COG1609	Transcriptional regulator
AXF14_10765	COG2190	(PTS) system
AXF14_10765	COG1263	PTS System
AXF14_10765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXF14_10780	COG2814	Major facilitator Superfamily
AXF14_10790	COG0443	Heat shock 70 kDa protein
AXF14_10795	COG0667	Aldo Keto reductase
AXF14_10825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AXF14_10845	COG4989	oxidoreductase activity
AXF14_10880	COG2818	Glycosylase
AXF14_10885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AXF14_10895	COG0662	Cupin 2, conserved barrel domain protein
AXF14_10900	COG1028	Short-chain dehydrogenase reductase Sdr
AXF14_10915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXF14_10920	COG0166	Belongs to the GPI family
AXF14_10925	COG1160	GTP binding
AXF14_10940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXF14_10960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXF14_10965	COG0149	triose-phosphate isomerase activity
AXF14_10975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXF14_10980	COG1481	regulation of sporulation
AXF14_10985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AXF14_10990	COG1660	Displays ATPase and GTPase activities
AXF14_10995	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AXF14_11010	COG0322	excinuclease ABC activity
AXF14_11015	COG0561	phosphatase activity
AXF14_11065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXF14_11080	COG0861	Integral membrane protein TerC family
AXF14_11085	COG0861	Integral membrane protein TerC family
AXF14_11090	COG0556	nucleotide-excision repair
AXF14_11095	COG0237	dephospho-CoA kinase activity
AXF14_11100	COG2076	Multidrug Resistance protein
AXF14_11105	COG0710	3-dehydroquinate dehydratase activity
AXF14_11110	COG0738	Major facilitator superfamily
AXF14_11115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXF14_11130	COG0539	negative regulation of cytoplasmic translation
AXF14_11140	COG2050	protein possibly involved in aromatic compounds catabolism
AXF14_11165	COG0070	glutamate synthase
AXF14_11165	COG0069	glutamate synthase activity
AXF14_11165	COG0067	glutamate synthase
AXF14_11170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AXF14_11175	COG0134	indole-3-glycerol-phosphate synthase activity
AXF14_11180	COG1297	OPT oligopeptide transporter protein
AXF14_11190	COG0107	imidazoleglycerol-phosphate synthase activity
AXF14_11205	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AXF14_11215	COG4122	O-methyltransferase activity
AXF14_11220	COG1222	aaa ATPase
AXF14_11235	COG2264	protein methyltransferase activity
AXF14_11245	COG4115	mRNA cleavage
AXF14_11250	COG1121	(ABC) transporter
AXF14_11255	COG1121	(ABC) transporter
AXF14_11270	COG0488	(ABC) transporter
AXF14_11295	COG2814	Major facilitator Superfamily
AXF14_11300	COG1994	Peptidase M50
AXF14_11300	COG0517	IMP dehydrogenase activity
AXF14_11310	COG2391	methyltransferase activity
AXF14_11315	COG0425	Belongs to the sulfur carrier protein TusA family
AXF14_11320	COG0667	Aldo Keto reductase
AXF14_11340	COG0028	Belongs to the TPP enzyme family
AXF14_11350	COG0738	Major facilitator superfamily
AXF14_11365	COG0676	glucose-6-phosphate 1-epimerase activity
AXF14_11380	COG0587	DNA-directed DNA polymerase activity
AXF14_11385	COG0833	amino acid
AXF14_11400	COG1435	thymidine kinase activity
AXF14_11420	COG1881	PFAM PEBP family protein
AXF14_11430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXF14_11445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXF14_11455	COG0531	amino acid
AXF14_11460	COG0569	domain protein
AXF14_11505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXF14_11510	COG1929	Belongs to the glycerate kinase type-1 family
AXF14_11520	COG0187	DNA topoisomerase II activity
AXF14_11535	COG0351	phosphomethylpyrimidine kinase
AXF14_11540	COG0352	thiamine-phosphate diphosphorylase activity
AXF14_11545	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AXF14_11550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXF14_11560	COG0515	serine threonine protein kinase
AXF14_11560	COG2815	serine threonine protein kinase
AXF14_11565	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AXF14_11570	COG0205	6-phosphofructokinase activity
AXF14_11605	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_11610	COG0488	(ABC) transporter
AXF14_11650	COG1119	ATPase activity
AXF14_11660	COG0297	glycogen (starch) synthase activity
AXF14_11670	COG0560	Phosphoserine phosphatase
AXF14_11680	COG1028	Short-chain dehydrogenase reductase Sdr
AXF14_11700	COG0423	glycine-tRNA ligase activity
AXF14_11715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXF14_11730	COG0549	Belongs to the carbamate kinase family
AXF14_11735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXF14_11740	COG1381	Involved in DNA repair and RecF pathway recombination
AXF14_11745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXF14_11760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXF14_11770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AXF14_11780	COG3876	Protein conserved in bacteria
AXF14_11795	COG0484	heat shock protein binding
AXF14_11800	COG1420	regulation of RNA biosynthetic process
AXF14_11845	COG2197	response regulator
AXF14_11860	COG3845	ABC transporter
AXF14_11890	COG2271	Major facilitator Superfamily
AXF14_11930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXF14_11940	COG0481	GTPase activity
AXF14_11960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXF14_11965	COG0512	Glutamine amidotransferase of anthranilate synthase
AXF14_11970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXF14_11980	COG0159	tryptophan synthase activity
AXF14_12000	COG0268	Binds directly to 16S ribosomal RNA
AXF14_12015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXF14_12015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXF14_12020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AXF14_12035	COG1555	photosystem II stabilization
AXF14_12040	COG1307	EDD domain protein, DegV family
AXF14_12045	COG0433	COG0433 Predicted ATPase
AXF14_12065	COG0495	leucyl-tRNA aminoacylation
AXF14_12070	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXF14_12075	COG0537	adenosine 5'-monophosphoramidase activity
AXF14_12095	COG0733	neurotransmitter:sodium symporter activity
AXF14_12100	COG0813	purine-nucleoside phosphorylase activity
AXF14_12115	COG3415	Transposase
AXF14_12115	COG2801	Transposase and inactivated derivatives
AXF14_12125	COG1940	carbohydrate kinase activity
AXF14_12165	COG2826	transposase and inactivated derivatives, IS30 family
AXF14_12185	COG0415	Belongs to the DNA photolyase family
AXF14_12220	COG0640	Transcriptional regulator
AXF14_12225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AXF14_12235	COG2814	Major facilitator Superfamily
AXF14_12260	COG0406	alpha-ribazole phosphatase activity
AXF14_12265	COG0799	negative regulation of ribosome biogenesis
AXF14_12275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXF14_12305	COG1132	(ABC) transporter
AXF14_12340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AXF14_12355	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AXF14_12360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXF14_12365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AXF14_12370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AXF14_12380	COG1271	oxidase subunit
AXF14_12385	COG1294	oxidase, subunit
AXF14_12395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AXF14_12410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXF14_12415	COG0571	ribonuclease III activity
AXF14_12440	COG0738	Major facilitator superfamily
AXF14_12445	COG4154	Belongs to the RbsD FucU family
AXF14_12450	COG1070	Carbohydrate kinase
AXF14_12460	COG0235	Class ii aldolase
AXF14_12475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXF14_12480	COG1461	Dihydroxyacetone kinase
AXF14_12485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXF14_12500	COG2814	Major facilitator Superfamily
AXF14_12515	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXF14_12525	COG3547	Transposase (IS116 IS110 IS902 family)
AXF14_12530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AXF14_12540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXF14_12545	COG0066	3-isopropylmalate dehydratase activity
AXF14_12565	COG0438	transferase activity, transferring glycosyl groups
AXF14_12570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXF14_12580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXF14_12600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXF14_12610	COG2813	Specifically methylates the guanine in position
AXF14_12620	COG1114	Component of the transport system for branched-chain amino acids
AXF14_12625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AXF14_12645	COG0523	cobalamin synthesis protein
AXF14_12650	COG2197	response regulator
AXF14_12660	COG1136	(ABC) transporter
AXF14_12660	COG0577	efflux transmembrane transporter activity
AXF14_12685	COG0596	Alpha beta hydrolase
AXF14_12690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXF14_12705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXF14_12705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXF14_12710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AXF14_12715	COG0509	glycine decarboxylation via glycine cleavage system
AXF14_12730	COG1252	NADH dehydrogenase
AXF14_12735	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AXF14_12740	COG2137	regulation of response to DNA damage stimulus
AXF14_12745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AXF14_12755	COG1396	sequence-specific DNA binding
AXF14_12760	COG1058	Belongs to the CinA family
AXF14_12760	COG1546	Belongs to the CinA family
AXF14_12770	COG3415	Transposase
AXF14_12770	COG2801	Transposase and inactivated derivatives
AXF14_12780	COG1674	ftsk spoiiie
AXF14_12790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AXF14_12815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXF14_12825	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXF14_12830	COG1115	amino acid carrier protein
AXF14_12835	COG1115	amino acid carrier protein
AXF14_12840	COG1115	amino acid carrier protein
AXF14_12845	COG1115	amino acid carrier protein
AXF14_12865	COG2040	homocysteine
AXF14_12870	COG0833	amino acid
AXF14_12875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXF14_12885	COG3304	Inner membrane component domain
AXF14_12925	COG3415	Transposase
AXF14_12925	COG2801	Transposase and inactivated derivatives