locus-tag	class	description
CHIBA101_0001	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CHIBA101_0002	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CHIBA101_0003	ENOG4105K7N	UPF0232 protein
CHIBA101_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CHIBA101_0005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CHIBA101_0016	ENOG4108U4N	(sortase) family
CHIBA101_0018	ENOG4105D9P	serine threonine protein kinase
CHIBA101_0019	ENOG4107TPY	serine threonine protein kinase
CHIBA101_0020	ENOG4105CJN	penicillin-binding protein
CHIBA101_0023	ENOG4105HZM	Fha domain containing protein
CHIBA101_0024	ENOG4105TV9	FHA Domain-Containing protein
CHIBA101_0028	ENOG4105D22	carbon starvation protein
CHIBA101_0030	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CHIBA101_0032	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_0041	ENOG4107QTF	adenylosuccinate lyase
CHIBA101_0042	ENOG41082T9	Membrane
CHIBA101_0047	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CHIBA101_0050	ENOG4105KME	endoribonuclease L-psp
CHIBA101_0053	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CHIBA101_0055	ENOG4105C4Y	ABC transporter
CHIBA101_0056	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CHIBA101_0057	ENOG4105BZU	Histidine kinase
CHIBA101_0066	ENOG4107TE5	Lipid kinase
CHIBA101_0067	ENOG4105C5Q	Transcriptional regulator
CHIBA101_0068	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CHIBA101_0069	ENOG410667J	hydrolase
CHIBA101_0071	ENOG4107QKS	N-acylglucosamine 2-epimerase
CHIBA101_0090	ENOG4107FW0	short-chain dehydrogenase reductase
CHIBA101_0092	ENOG4107EEY	synthase
CHIBA101_0093	ENOG4105CEY	Amp-dependent synthetase and ligase
CHIBA101_0095	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CHIBA101_0102	ENOG4105C28	cystathionine
CHIBA101_0111	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_0116	ENOG4105DF6	Fe-S oxidoreductase
CHIBA101_0121	ENOG4108UCS	ABC, transporter
CHIBA101_0131	ENOG4105C0D	helicase
CHIBA101_0147	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CHIBA101_0148	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CHIBA101_0151	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CHIBA101_0154	ENOG41062D9	Histidine kinase
CHIBA101_0157	ENOG4105VUN	Transcriptional regulator
CHIBA101_0164	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CHIBA101_0167	ENOG4105CFH	Aspartokinase
CHIBA101_0171	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CHIBA101_0172	ENOG4105D52	delta-aminolevulinic acid dehydratase
CHIBA101_0174	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CHIBA101_0176	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CHIBA101_0177	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CHIBA101_0178	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CHIBA101_0179	ENOG4107JTW	chlorite dismutase
CHIBA101_0180	ENOG41080RH	Thioredoxin
CHIBA101_0185	ENOG4108X07	Tetr family transcriptional regulator
CHIBA101_0186	ENOG4105CIG	ABC transporter
CHIBA101_0208	ENOG4105EC2	ftsk spoIIIe
CHIBA101_0212	ENOG4108IUK	alpha amylase, catalytic
CHIBA101_0216	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CHIBA101_0217	ENOG4105CC5	ABC transporter
CHIBA101_0218	ENOG4107RPQ	ABC transporter
CHIBA101_0219	ENOG4105DIK	(ABC) transporter
CHIBA101_0220	ENOG4107SIG	periplasmic solute binding protein
CHIBA101_0222	ENOG4105CE1	Ferrous iron transport protein b
CHIBA101_0223	ENOG4105CE1	Ferrous iron transport protein b
CHIBA101_0226	ENOG4107TE5	Lipid kinase
CHIBA101_0229	ENOG4108PSK	reductase
CHIBA101_0231	ENOG4105BZ4	penicillin-binding protein
CHIBA101_0234	ENOG4105IJJ	transcriptional regulator, crp fnr family
CHIBA101_0237	ENOG4108J2P	Alpha beta hydrolase fold
CHIBA101_0239	ENOG4108UMN	azlc family
CHIBA101_0246	ENOG4105U0R	haloacid dehalogenase-like hydrolase
CHIBA101_0249	ENOG4105D3R	alkyl hydroperoxide reductase
CHIBA101_0255	ENOG4105BZU	Histidine kinase
CHIBA101_0256	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CHIBA101_0259	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CHIBA101_0262	ENOG4105CSH	Transporter
CHIBA101_0266	ENOG4105DBV	ornithine carbamoyltransferase
CHIBA101_0267	ENOG4105CEU	Arginine dihydrolase
CHIBA101_0268	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CHIBA101_0269	ENOG4105I8F	Histidine kinase
CHIBA101_0270	ENOG4105CDV	Ompa motb domain protein
CHIBA101_0273	ENOG4107QRG	dna polymerase iii
CHIBA101_0277	ENOG4105HDK	L-asparaginase
CHIBA101_0282	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CHIBA101_0284	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CHIBA101_0286	ENOG4105K8R	UPF0145 protein
CHIBA101_0289	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CHIBA101_0291	ENOG4105CQ7	ATP-dependent helicase
CHIBA101_0291	ENOG4105CQ7	ATP-dependent helicase
CHIBA101_0296	ENOG4106N3A	copper homeostasis protein cutc
CHIBA101_0298	ENOG4105EN6	Membrane
CHIBA101_0306	ENOG4108ZF3	Phosphatase
CHIBA101_0312	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CHIBA101_0322	ENOG4108DBC	nitroreductase
CHIBA101_0323	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CHIBA101_0327	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CHIBA101_0332	ENOG4105DHP	deoxycytidine triphosphate deaminase
CHIBA101_0335	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CHIBA101_0337	ENOG4108DBC	nitroreductase
CHIBA101_0340	ENOG4105EMU	Dehydrogenase
CHIBA101_0342	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CHIBA101_0344	ENOG4107RCW	fructose-bisphosphate aldolase
CHIBA101_0351	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CHIBA101_0354	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
CHIBA101_0356	ENOG4105C12	Phosphoribosylglycinamide synthetase
CHIBA101_0357	ENOG4105C8V	SAICAR synthetase
CHIBA101_0360	ENOG410839H	phosphoribosylformylglycinamidine synthase
CHIBA101_0361	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CHIBA101_0362	ENOG41088YS	Glycosyl transferase (Group 1
CHIBA101_0363	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CHIBA101_0371	ENOG4105D82	Glutamate dehydrogenase
CHIBA101_0372	ENOG4105E98	transcriptional regulator DeoR family
CHIBA101_0373	ENOG4105DE4	1-phosphofructokinase
CHIBA101_0374	ENOG4105DM4	PTS System
CHIBA101_0377	ENOG4105FDP	GntR family transcriptional regulator
CHIBA101_0379	ENOG4105ZXK	Dehydrogenase
CHIBA101_0380	ENOG4105C6Z	Gluconate
CHIBA101_0382	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CHIBA101_0388	ENOG4105BZ1	(ABC) transporter
CHIBA101_0389	ENOG4105BZ1	(ABC) transporter
CHIBA101_0390	ENOG4107RBB	ABC transporter, permease
CHIBA101_0391	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CHIBA101_0394	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CHIBA101_0403	ENOG4105QAX	Iron-sulfur
CHIBA101_0404	ENOG4107QY8	reductase
CHIBA101_0407	ENOG4105E0X	reductase
CHIBA101_0411	ENOG4105C1J	atp-dependent rna helicase
CHIBA101_0413	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
CHIBA101_0417	ENOG4105K56	Transcriptional regulator
CHIBA101_0418	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CHIBA101_0422	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CHIBA101_0423	ENOG4105C6Z	Gluconate
CHIBA101_0428	ENOG4105CJ3	phosphate transporter
CHIBA101_0430	ENOG4107NHD	transcriptional regulator
CHIBA101_0433	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
CHIBA101_0436	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CHIBA101_0438	ENOG4105D7T	ABC transporter
CHIBA101_0442	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CHIBA101_0443	ENOG4105CSH	Transporter
CHIBA101_0445	ENOG4107RA4	Glycosyl transferase (Group 1
CHIBA101_0447	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CHIBA101_0448	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CHIBA101_0459	ENOG4105K6V	RNA polymerase
CHIBA101_0461	ENOG4105R3P	Inner membrane protein yagU
CHIBA101_0462	ENOG4107SIQ	Naphthoate synthase
CHIBA101_0463	ENOG4105CEU	Arginine dihydrolase
CHIBA101_0466	ENOG4107TCW	O-succinylbenzoate synthase
CHIBA101_0467	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CHIBA101_0471	ENOG4105DWV	Homoserine O-trans-acetylase
CHIBA101_0472	ENOG4108IQK	o-acetylhomoserine
CHIBA101_0474	ENOG4105F0N	pyrophosphate phospho-hydrolase
CHIBA101_0477	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CHIBA101_0478	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CHIBA101_0479	ENOG4105EUJ	GTP cyclohydrolase i
CHIBA101_0481	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_0485	ENOG4105BZ1	(ABC) transporter
CHIBA101_0491	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CHIBA101_0492	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CHIBA101_0493	ENOG4105EEI	dihydropteroate synthase
CHIBA101_0499	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CHIBA101_0500	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CHIBA101_0502	ENOG4105CRK	lysyL-tRNA synthetase
CHIBA101_0504	ENOG4105DUX	Transporter
CHIBA101_0506	ENOG4105DEI	Mannitol dehydrogenase
CHIBA101_0507	ENOG4105IE8	Alpha-ketoglutarate permease
CHIBA101_0509	ENOG41080R8	Conserved Protein
CHIBA101_0511	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CHIBA101_0512	ENOG4105DAA	L-lactate
CHIBA101_0513	ENOG4105C59	p-type ATPase
CHIBA101_0515	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CHIBA101_0516	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CHIBA101_0517	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CHIBA101_0518	ENOG4105DKT	Transcriptional regulator
CHIBA101_0520	ENOG4107YVI	ribose 5-phosphate isomerase
CHIBA101_0522	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
CHIBA101_0523	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
CHIBA101_0525	ENOG4105EF1	ribulokinase
CHIBA101_0526	ENOG4105DKT	Transcriptional regulator
CHIBA101_0532	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
CHIBA101_0536	ENOG4105CM4	permease protein
CHIBA101_0537	ENOG4108IPW	abc transporter atp-binding protein
CHIBA101_0540	ENOG4105H6Q	decarboxylase
CHIBA101_0543	ENOG4107RGD	Major Facilitator superfamily
CHIBA101_0547	ENOG4105CMT	Dihydroxyacetone kinase
CHIBA101_0548	ENOG4108UTZ	Dihydroxyacetone kinase
CHIBA101_0549	ENOG4107WI4	Aldose-1-epimerase
CHIBA101_0551	ENOG4105CZN	Potassium uptake protein
CHIBA101_0553	ENOG4107R4N	Cell wall formation (By similarity)
CHIBA101_0559	ENOG4105XTG	Pfam:DUF156
CHIBA101_0560	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CHIBA101_0567	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CHIBA101_0568	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CHIBA101_0569	ENOG4108VZM	50s ribosomal protein L10
CHIBA101_0570	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CHIBA101_0582	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CHIBA101_0583	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CHIBA101_0584	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CHIBA101_0589	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CHIBA101_0590	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CHIBA101_0591	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CHIBA101_0592	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CHIBA101_0595	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CHIBA101_0597	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CHIBA101_0598	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CHIBA101_0599	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHIBA101_0600	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CHIBA101_0601	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CHIBA101_0602	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CHIBA101_0603	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CHIBA101_0604	ENOG41082SA	50s ribosomal protein l29
CHIBA101_0605	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CHIBA101_0607	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CHIBA101_0608	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CHIBA101_0609	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHIBA101_0610	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CHIBA101_0612	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CHIBA101_0614	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CHIBA101_0615	ENOG410849U	50S ribosomal protein L30
CHIBA101_0616	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CHIBA101_0617	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CHIBA101_0618	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CHIBA101_0619	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CHIBA101_0620	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CHIBA101_0621	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHIBA101_0622	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CHIBA101_0623	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CHIBA101_0624	ENOG4108ZT0	50S ribosomal protein l17
CHIBA101_0628	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CHIBA101_0629	ENOG4108UJD	30S ribosomal protein S9
CHIBA101_0631	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CHIBA101_0632	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CHIBA101_0633	ENOG4105CS9	pantothenic acid kinase
CHIBA101_0636	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CHIBA101_0637	ENOG4108097	ATP-binding protein
CHIBA101_0643	ENOG4105E33	succinate dehydrogenase
CHIBA101_0646	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CHIBA101_0648	ENOG4107GZ4	SanA protein
CHIBA101_0649	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CHIBA101_0650	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CHIBA101_0653	ENOG410849S	phosphocarrier protein (HPr)
CHIBA101_0655	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CHIBA101_0658	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
CHIBA101_0659	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CHIBA101_0660	ENOG4107P2S	Transcriptional regulator
CHIBA101_0662	ENOG4107QNK	)-transporter
CHIBA101_0663	ENOG4105CK5	oxidoreductase
CHIBA101_0664	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_0665	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_0667	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CHIBA101_0668	ENOG4105FDP	GntR family transcriptional regulator
CHIBA101_0671	ENOG4105DH8	myo-inositol catabolism
CHIBA101_0672	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CHIBA101_0673	ENOG4105C26	Dehydrogenase
CHIBA101_0675	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CHIBA101_0676	ENOG4105F0H	myo-inositol catabolism protein
CHIBA101_0677	ENOG4107QNK	)-transporter
CHIBA101_0682	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CHIBA101_0690	ENOG4105CPC	Aldo Keto reductase
CHIBA101_0698	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_0701	ENOG4105ESV	Glycosyl transferase, family 4
CHIBA101_0703	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
CHIBA101_0704	ENOG4105ZA1	atp synthase
CHIBA101_0705	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CHIBA101_0706	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CHIBA101_0707	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CHIBA101_0708	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CHIBA101_0709	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CHIBA101_0710	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CHIBA101_0715	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
CHIBA101_0717	ENOG4105CE4	GlcNAc 6-P deacetylase
CHIBA101_0724	ENOG4106032	Glutathionylspermidine synthase
CHIBA101_0726	ENOG4108638	50S ribosomal protein L36
CHIBA101_0727	ENOG4105NRA	50s ribosomal protein l31 type b
CHIBA101_0728	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CHIBA101_0729	ENOG4105W0E	50S ribosomal protein L33
CHIBA101_0730	ENOG4105KDC	50s ribosomal protein l28
CHIBA101_0732	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CHIBA101_0733	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CHIBA101_0734	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CHIBA101_0735	ENOG4105CGK	Exodeoxyribonuclease III
CHIBA101_0737	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CHIBA101_0740	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CHIBA101_0742	ENOG4107SIG	periplasmic solute binding protein
CHIBA101_0743	ENOG4105DIK	(ABC) transporter
CHIBA101_0744	ENOG4105CC5	ABC transporter
CHIBA101_0745	ENOG4107RPQ	ABC transporter
CHIBA101_0746	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
CHIBA101_0747	ENOG4108URH	decarboxylase
CHIBA101_0750	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CHIBA101_0753	ENOG4105CJW	magnesium transporter
CHIBA101_0755	ENOG4105PGM	cation diffusion facilitator family transporter
CHIBA101_0761	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CHIBA101_0762	ENOG4105C1J	atp-dependent rna helicase
CHIBA101_0777	ENOG4105C5Q	Transcriptional regulator
CHIBA101_0779	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CHIBA101_0782	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CHIBA101_0783	ENOG4105BZ1	(ABC) transporter
CHIBA101_0785	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CHIBA101_0788	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CHIBA101_0794	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CHIBA101_0797	ENOG4105MP0	transposase
CHIBA101_0802	ENOG4105CG3	alpha amylase, catalytic region
CHIBA101_0818	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CHIBA101_0821	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
CHIBA101_0822	ENOG4105C31	Tryptophanyl-tRNA synthetase
CHIBA101_0825	ENOG4105BZJ	Electron transfer flavoprotein
CHIBA101_0826	ENOG4105C10	Electron transfer flavoprotein
CHIBA101_0828	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CHIBA101_0830	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CHIBA101_0832	ENOG4108VWQ	crispr-associated protein
CHIBA101_0833	ENOG41060M0	Crispr-associated protein, cse4 family
CHIBA101_0837	ENOG410684T	prevent-host-death family
CHIBA101_0839	ENOG4105DKT	Transcriptional regulator
CHIBA101_0840	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CHIBA101_0841	ENOG4105EDR	glucose galactose transporter
CHIBA101_0843	ENOG4108RVA	ribokinase
CHIBA101_0847	ENOG4105DET	Rhamnulokinase
CHIBA101_0851	ENOG4105DJZ	UPF0182 protein
CHIBA101_0853	ENOG4105BZU	Histidine kinase
CHIBA101_0854	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_0855	ENOG4105C9Q	fumarate hydratase class II
CHIBA101_0859	ENOG4105E98	transcriptional regulator DeoR family
CHIBA101_0862	ENOG4105MP0	transposase
CHIBA101_0863	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
CHIBA101_0865	ENOG4105VUN	Transcriptional regulator
CHIBA101_0866	ENOG4108IJ8	ABC transporter
CHIBA101_0870	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_0872	ENOG4105CK5	oxidoreductase
CHIBA101_0873	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
CHIBA101_0874	ENOG4107QNK	)-transporter
CHIBA101_0876	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CHIBA101_0877	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CHIBA101_0883	ENOG4105EC2	ftsk spoIIIe
CHIBA101_0885	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CHIBA101_0887	ENOG4108IUX	(ABC) transporter
CHIBA101_0889	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CHIBA101_0890	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CHIBA101_0893	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CHIBA101_0897	ENOG4105DA5	(ABC) transporter
CHIBA101_0898	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_0899	ENOG4105BZU	Histidine kinase
CHIBA101_0902	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CHIBA101_0904	ENOG4108WQH	regulatoR
CHIBA101_0906	ENOG4107TXC	Transcriptional regulator
CHIBA101_0908	ENOG4108S01	response regulator
CHIBA101_0909	ENOG4105BZU	Histidine kinase
CHIBA101_0911	ENOG4105CJ1	ABC, transporter
CHIBA101_0913	ENOG4105K5M	30s ribosomal protein S16
CHIBA101_0914	ENOG41082KU	UPF0109 protein
CHIBA101_0916	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CHIBA101_0917	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CHIBA101_0918	ENOG4107QYR	Signal peptidase i
CHIBA101_0919	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CHIBA101_0920	ENOG4107QYR	Signal peptidase i
CHIBA101_0921	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CHIBA101_0923	ENOG4105VFF	UPF0102 protein
CHIBA101_0924	ENOG4105C0P	Mg chelatase subunit ChlI
CHIBA101_0926	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CHIBA101_0929	ENOG4105CE9	30S ribosomal protein S2
CHIBA101_0930	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CHIBA101_0933	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CHIBA101_0934	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CHIBA101_0935	ENOG4105KNE	Phosphatidate cytidylyltransferase
CHIBA101_0936	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CHIBA101_0938	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CHIBA101_0939	ENOG4105DZP	Membrane-associated zinc metalloprotease
CHIBA101_0940	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CHIBA101_0942	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CHIBA101_0944	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
CHIBA101_0947	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CHIBA101_0947	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CHIBA101_0952	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CHIBA101_0953	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CHIBA101_0960	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CHIBA101_0961	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CHIBA101_0962	ENOG4105C1V	Peptidase, M16
CHIBA101_0963	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CHIBA101_0966	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CHIBA101_0967	ENOG4105CV8	reductase
CHIBA101_0968	ENOG4105CEY	Amp-dependent synthetase and ligase
CHIBA101_0972	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CHIBA101_0974	ENOG4108V6E	Cell division protein mraZ
CHIBA101_0975	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CHIBA101_0977	ENOG4105CJN	penicillin-binding protein
CHIBA101_0978	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CHIBA101_0980	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CHIBA101_0981	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CHIBA101_0982	ENOG4105CNI	cell division protein FtsW
CHIBA101_0983	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CHIBA101_0984	ENOG4105DFU	Cell wall formation (By similarity)
CHIBA101_0986	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CHIBA101_0987	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CHIBA101_0988	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CHIBA101_0990	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
CHIBA101_0995	ENOG4105C0B	DNA polymerase III (alpha subunit)
CHIBA101_0996	ENOG410848D	S4 domain protein YaaA
CHIBA101_1000	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CHIBA101_1004	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CHIBA101_1007	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CHIBA101_1011	ENOG4105EEQ	Na H antiporter
CHIBA101_1013	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CHIBA101_1016	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CHIBA101_1017	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CHIBA101_1021	ENOG4105DPH	UPF0371 protein
CHIBA101_1022	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CHIBA101_1025	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CHIBA101_1027	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CHIBA101_1028	ENOG4105RGK	anthranilate synthase component ii
CHIBA101_1029	ENOG4105CRQ	synthase (Component I)
CHIBA101_1030	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CHIBA101_1033	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CHIBA101_1035	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CHIBA101_1036	ENOG4105DJ2	Major Facilitator Superfamily
CHIBA101_1038	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CHIBA101_1040	ENOG4105CXY	transporter
CHIBA101_1042	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CHIBA101_1043	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CHIBA101_1044	ENOG4105DFA	alanine racemase domain protein
CHIBA101_1045	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CHIBA101_1047	ENOG4105CIG	ABC transporter
CHIBA101_1052	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CHIBA101_1054	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CHIBA101_1057	ENOG4105VZ8	Transcriptional regulator
CHIBA101_1060	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CHIBA101_1061	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
CHIBA101_1062	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CHIBA101_1063	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
CHIBA101_1064	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CHIBA101_1065	ENOG4105CC5	ABC transporter
CHIBA101_1066	ENOG4105FDK	ABC transporter
CHIBA101_1069	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
CHIBA101_1074	ENOG4105EAC	phosphoserine phosphatase
CHIBA101_1075	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CHIBA101_1076	ENOG4107QPH	glycogen) synthase
CHIBA101_1079	ENOG4105DKW	ABC transporter
CHIBA101_1084	ENOG4105C5H	ABC transporter
CHIBA101_1093	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CHIBA101_1097	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CHIBA101_1099	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
CHIBA101_1100	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CHIBA101_1101	ENOG4105DWF	phosphomethylpyrimidine kinase
CHIBA101_1105	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CHIBA101_1107	ENOG4105CD3	dihydroorotase
CHIBA101_1116	ENOG4107VEG	TrkA-N domain protein
CHIBA101_1117	ENOG4105C0X	amino acid
CHIBA101_1118	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CHIBA101_1119	ENOG4107QM5	aconitate hydratase
CHIBA101_1120	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_1125	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CHIBA101_1126	ENOG4105EMU	Dehydrogenase
CHIBA101_1127	ENOG4108V1U	phospholipid-binding protein
CHIBA101_1131	ENOG4108IQI	permease
CHIBA101_1132	ENOG4105C0B	DNA polymerase III (alpha subunit)
CHIBA101_1134	ENOG4105DSB	aldose 1-epimerase
CHIBA101_1140	ENOG4105C57	major facilitator superfamily
CHIBA101_1142	ENOG4107QN2	dihydrolipoyl dehydrogenase
CHIBA101_1144	ENOG4105CPC	Aldo Keto reductase
CHIBA101_1146	ENOG4105CUC	YeeE YedE family protein
CHIBA101_1150	ENOG4105C2C	drug resistance transporter, Bcr CflA
CHIBA101_1151	ENOG4106H3A	restriction
CHIBA101_1153	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
CHIBA101_1154	ENOG4105E5F	proteasome
CHIBA101_1155	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
CHIBA101_1156	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
CHIBA101_1158	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CHIBA101_1163	ENOG4105EPD	Oligopeptide transporter, Opt family
CHIBA101_1164	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CHIBA101_1165	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CHIBA101_1169	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
CHIBA101_1172	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CHIBA101_1174	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CHIBA101_1176	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CHIBA101_1183	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CHIBA101_1187	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CHIBA101_1188	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
CHIBA101_1189	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
CHIBA101_1195	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CHIBA101_1196	ENOG4105C5Y	PTS System
CHIBA101_1198	ENOG4105CID	antiterminator
CHIBA101_1200	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CHIBA101_1201	ENOG4105CHW	UPF0052 protein
CHIBA101_1202	ENOG4105CIE	May be required for sporulation (By similarity)
CHIBA101_1203	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CHIBA101_1204	ENOG4105BZA	Phosphoglycerate kinase
CHIBA101_1205	ENOG4105CP7	Triose-phosphate isomerase
CHIBA101_1209	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CHIBA101_1210	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CHIBA101_1213	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CHIBA101_1214	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CHIBA101_1216	ENOG4107QP8	phosphohexose isomerase
CHIBA101_1226	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
CHIBA101_1230	ENOG4107QM2	Aldo Keto reductase
CHIBA101_1234	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CHIBA101_1236	ENOG4108UW8	fha domain-containing protein
CHIBA101_1240	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CHIBA101_1241	ENOG4105C5Y	PTS System
CHIBA101_1242	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_1245	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CHIBA101_1249	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CHIBA101_1252	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CHIBA101_1253	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CHIBA101_1271	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
CHIBA101_1272	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CHIBA101_1273	ENOG4107XKF	NMT1 THI5 Like Domain Protein
CHIBA101_1274	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
CHIBA101_1276	ENOG4108RWI	nicotinamidase
CHIBA101_1278	ENOG4105CK7	Sodium proline symporter
CHIBA101_1279	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CHIBA101_1280	ENOG4105D8K	carboxyl transferase
CHIBA101_1281	ENOG4108JIK	carboxylase
CHIBA101_1283	ENOG4105DJV	ribulose-phosphate 3-epimerase
CHIBA101_1285	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CHIBA101_1289	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CHIBA101_1291	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CHIBA101_1293	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CHIBA101_1295	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
CHIBA101_1296	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CHIBA101_1297	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CHIBA101_1298	ENOG4105CD3	dihydroorotase
CHIBA101_1299	ENOG4105CXT	aspartate transcarbamylase
CHIBA101_1300	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CHIBA101_1305	ENOG4105CHR	reductase
CHIBA101_1306	ENOG41062T2	Acyl carrier protein
CHIBA101_1307	ENOG4108KQ6	Enoyl-CoA hydratase
CHIBA101_1308	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
CHIBA101_1310	ENOG4107SQU	synthase
CHIBA101_1311	ENOG4105C0W	non-ribosomal peptide synthetase
CHIBA101_1312	ENOG4107SQU	synthase
CHIBA101_1312	ENOG4107SQU	synthase
CHIBA101_1313	ENOG4107SQU	synthase
CHIBA101_1316	ENOG4107SQU	synthase
CHIBA101_1317	ENOG4108MGH	Enoyl-CoA hydratase
CHIBA101_1318	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CHIBA101_1322	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CHIBA101_1325	ENOG4105BZU	Histidine kinase
CHIBA101_1326	ENOG410803B	Involved in the transcription termination process (By similarity)
CHIBA101_1327	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CHIBA101_1329	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CHIBA101_1330	ENOG4105D49	3-dehydroquinate synthase
CHIBA101_1331	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CHIBA101_1332	ENOG4105E2X	shikimate dehydrogenase
CHIBA101_1334	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CHIBA101_1335	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CHIBA101_1336	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CHIBA101_1339	ENOG4107R13	MMPL domain protein
CHIBA101_1340	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CHIBA101_1341	ENOG41080HT	Transcriptional regulator, arsr family
CHIBA101_1343	ENOG4105C9M	aspartyl-trna synthetase
CHIBA101_1347	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHIBA101_1349	ENOG4105CUT	histidyl-tRNA synthetase
CHIBA101_1353	ENOG4105C99	atpase involved in dna repair
CHIBA101_1354	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CHIBA101_1355	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CHIBA101_1356	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CHIBA101_1357	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CHIBA101_1359	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CHIBA101_1360	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CHIBA101_1361	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CHIBA101_1362	ENOG4105CDY	transcriptional regulatory protein
CHIBA101_1363	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CHIBA101_1366	ENOG4105E2K	Glycosyl transferase (Group 1
CHIBA101_1367	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
CHIBA101_1368	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
CHIBA101_1370	ENOG4105C22	threonyL-tRNA synthetase
CHIBA101_1372	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CHIBA101_1384	ENOG4105C6N	Formate acetyltransferase
CHIBA101_1389	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CHIBA101_1393	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CHIBA101_1394	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CHIBA101_1396	ENOG4105C5F	glutamine synthetase
CHIBA101_1398	ENOG4105E5Q	amino acid AbC transporter
CHIBA101_1399	ENOG4108JEH	abc transporter atp-binding protein
CHIBA101_1401	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CHIBA101_1402	ENOG4105C5F	glutamine synthetase
CHIBA101_1403	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CHIBA101_1407	ENOG4107XFJ	UPF0246 protein
CHIBA101_1409	ENOG4105EGD	dinuclear metal center protein, YbgI family
CHIBA101_1411	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CHIBA101_1422	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CHIBA101_1423	ENOG4108IJ0	Aspartate ammonia-lyase
CHIBA101_1425	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CHIBA101_1428	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CHIBA101_1433	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CHIBA101_1434	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CHIBA101_1437	ENOG4105D56	permease protein
CHIBA101_1438	ENOG4105EG2	ABC transporter, permease
CHIBA101_1441	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CHIBA101_1443	ENOG4105CPC	Aldo Keto reductase
CHIBA101_1444	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CHIBA101_1447	ENOG4105KNE	Phosphatidate cytidylyltransferase
CHIBA101_1449	ENOG4105K78	MarR family Transcriptional regulator
CHIBA101_1451	ENOG4105CIG	ABC transporter
CHIBA101_1454	ENOG4105VG1	fes assembly suf system protein
CHIBA101_1455	ENOG4107YH3	SUF system FeS assembly protein, NifU family
CHIBA101_1457	ENOG4105C3K	feS assembly ATPase SufC
CHIBA101_1459	ENOG4105DIW	FeS assembly protein SUFB
CHIBA101_1462	ENOG4105ECY	inositol monophosphatase
CHIBA101_1468	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CHIBA101_1472	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CHIBA101_1473	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CHIBA101_1476	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
CHIBA101_1481	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CHIBA101_1483	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CHIBA101_1484	ENOG4108VX5	3-methyladenine DNA glycosylase
CHIBA101_1485	ENOG4105CH7	arginosuccinase
CHIBA101_1487	ENOG4105CDH	Citrulline--aspartate ligase
CHIBA101_1489	ENOG4105C8Y	Acetylornithine aminotransferase
CHIBA101_1490	ENOG4105CAS	nag kinase
CHIBA101_1491	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CHIBA101_1492	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CHIBA101_1494	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CHIBA101_1495	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CHIBA101_1497	ENOG4105DRP	amino acid AbC transporter
CHIBA101_1498	ENOG4105EAD	ABC transporter
CHIBA101_1499	ENOG4107RP9	extracellular solute-binding protein, family 3
CHIBA101_1500	ENOG4105CDA	abc transporter atp-binding protein
CHIBA101_1501	ENOG4108RWN	rrna methyltransferase
CHIBA101_1502	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CHIBA101_1503	ENOG41084BS	50S ribosomal protein L35
CHIBA101_1504	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CHIBA101_1510	ENOG4105D1H	recombination factor protein RarA
CHIBA101_1513	ENOG4105EPR	degv family
CHIBA101_1514	ENOG4105D7A	ATP-binding protein
CHIBA101_1515	ENOG4105C8T	Leucyl-tRNA synthetase
CHIBA101_1516	ENOG4107ZUX	Histidine triad (HIT) protein
CHIBA101_1522	ENOG4105C8J	)-transporter
CHIBA101_1530	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CHIBA101_1531	ENOG4105E98	transcriptional regulator DeoR family
CHIBA101_1532	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CHIBA101_1534	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CHIBA101_1535	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHIBA101_1536	ENOG4105K46	50S ribosomal protein l27
CHIBA101_1537	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CHIBA101_1539	ENOG4105CRE	cytochrome C
CHIBA101_1541	ENOG4107QIV	Cytochrome c biogenesis protein
CHIBA101_1544	ENOG4108W6G	cytochrome C
CHIBA101_1545	ENOG4105C03	ribonuclease
CHIBA101_1546	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CHIBA101_1547	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CHIBA101_1548	ENOG4108JJ9	ABC, transporter
CHIBA101_1549	ENOG4108JJ8	(ABC) transporter
CHIBA101_1552	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CHIBA101_1553	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CHIBA101_1556	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CHIBA101_1561	ENOG4105DP4	dak2 domain fusion protein ylov
CHIBA101_1562	ENOG4105VB9	50S ribosomal protein l28
CHIBA101_1564	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
CHIBA101_1566	ENOG4105CPF	Cell wall formation (By similarity)
CHIBA101_1569	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CHIBA101_1571	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CHIBA101_1572	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CHIBA101_1573	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CHIBA101_1578	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CHIBA101_1580	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CHIBA101_1583	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CHIBA101_1585	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CHIBA101_1587	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CHIBA101_1588	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CHIBA101_1589	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CHIBA101_1594	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CHIBA101_1595	ENOG4105E2R	ROK family
CHIBA101_1598	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
CHIBA101_1600	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CHIBA101_1601	ENOG4105KC9	Modulates RecA activity (By similarity)
CHIBA101_1602	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CHIBA101_1604	ENOG4105WBV	Transcriptional regulator
CHIBA101_1605	ENOG4105CEV	competence damage-inducible protein
CHIBA101_1608	ENOG4107QZI	cell division protein FtsK
CHIBA101_1619	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CHIBA101_1622	ENOG4105C87	Aminotransferase class I and II
CHIBA101_1624	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CHIBA101_1625	ENOG4105BZG	amino acid carrier protein
CHIBA101_1633	ENOG4107QK5	Homocysteine s-methyltransferase
CHIBA101_1634	ENOG4108IQI	permease
CHIBA101_1635	ENOG410901E	Membrane
CHIBA101_1646	ENOG4105CDA	abc transporter atp-binding protein
CHIBA101_1650	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CHIBA101_1651	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CHIBA101_1653	ENOG4108RQ5	Beta-lactamase domain-containing protein
CHIBA101_1654	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CHIBA101_1656	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CHIBA101_1660	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CHIBA101_1662	ENOG4105CJ1	ABC, transporter
CHIBA101_1663	ENOG4108426	dNA-binding protein
CHIBA101_1664	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
CHIBA101_1665	ENOG4105DKQ	ROK family
CHIBA101_1668	ENOG4108JQ7	(ABC) transporter
CHIBA101_1671	ENOG4108J59	Extracellular solute-binding protein, family 5
CHIBA101_1672	ENOG4105FDP	GntR family transcriptional regulator
CHIBA101_1674	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CHIBA101_1676	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
CHIBA101_1677	ENOG4105CAK	Cell division ATP-binding protein ftsE
CHIBA101_1683	ENOG4105IDI	abc transporter atp-binding protein
CHIBA101_1684	ENOG4108UGD	Serine Threonine protein kinase
CHIBA101_1685	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CHIBA101_1691	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CHIBA101_1700	ENOG4105K64	Glycosyl transferase, family 2
CHIBA101_1701	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
CHIBA101_1703	ENOG4108KGH	TRANSCRIPTIONal
CHIBA101_1704	ENOG4107SJB	teichoic acid biosynthesis
CHIBA101_1705	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CHIBA101_1706	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CHIBA101_1707	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CHIBA101_1710	ENOG4105D0C	transport protein
CHIBA101_1712	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_1713	ENOG4105D7K	pfkb domain protein
CHIBA101_1714	ENOG4105DRS	transport system, permease
CHIBA101_1715	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CHIBA101_1719	ENOG410836F	Transposase
CHIBA101_1724	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CHIBA101_1725	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CHIBA101_1726	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CHIBA101_1728	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CHIBA101_1729	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CHIBA101_1730	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CHIBA101_1731	ENOG4105D3Q	Sugar transferase
CHIBA101_1732	ENOG4107YJ4	chain length determinant protein
CHIBA101_1734	ENOG4108UW5	maltose o-acetyltransferase
CHIBA101_1736	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CHIBA101_1741	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CHIBA101_1742	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CHIBA101_1745	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CHIBA101_1746	ENOG410635A	Membrane
CHIBA101_1749	ENOG4105II7	pyrroline-5-carboxylate reductase
CHIBA101_1750	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
CHIBA101_1751	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
CHIBA101_1752	ENOG4105E5F	proteasome
CHIBA101_1753	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
CHIBA101_1757	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CHIBA101_1758	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CHIBA101_1759	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CHIBA101_1760	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CHIBA101_1761	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CHIBA101_1766	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CHIBA101_1774	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CHIBA101_1780	ENOG4105MZU	cell filamentation protein
CHIBA101_1783	ENOG4107QRT	dEAD DEAH box helicase
CHIBA101_1794	ENOG4108RCM	Nitroreductase
CHIBA101_1798	ENOG41067C8	50S ribosomal protein L32
CHIBA101_1799	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CHIBA101_1801	ENOG4105D7W	serine acetyltransferase
CHIBA101_1803	ENOG4105BZW	Glycerate kinase
CHIBA101_1804	ENOG4108YZG	isomerase
CHIBA101_1806	ENOG4105C9K	Endothelin-converting enzyme 1
CHIBA101_1810	ENOG4105FDP	GntR family transcriptional regulator
CHIBA101_1813	ENOG4105C5Y	PTS System
CHIBA101_1815	ENOG4105CI1	PTS System
CHIBA101_1816	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CHIBA101_1817	ENOG4105C29	acyl-CoA thioesterase
CHIBA101_1821	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CHIBA101_1822	ENOG4105CTQ	phosphohexokinase
CHIBA101_1824	ENOG4105CG3	alpha amylase, catalytic region
CHIBA101_1826	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
CHIBA101_1835	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_1836	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
CHIBA101_1837	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CHIBA101_1841	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CHIBA101_1842	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CHIBA101_1843	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CHIBA101_1848	ENOG4108PJD	permease
CHIBA101_1850	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CHIBA101_1851	ENOG4105D6E	homoserine dehydrogenase
CHIBA101_1854	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CHIBA101_1855	ENOG4105C75	arginyL-tRNA synthetase
CHIBA101_1858	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
CHIBA101_1861	ENOG4105C37	(CBS) domain
CHIBA101_1862	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CHIBA101_1866	ENOG4105WMN	AntiSigma factor
CHIBA101_1867	ENOG4105EMN	RNA polymerase sigma factor
CHIBA101_1871	ENOG4105DA5	(ABC) transporter
CHIBA101_1874	ENOG410836F	Transposase
CHIBA101_1877	ENOG4105E9K	Isocitrate dehydrogenase
CHIBA101_1880	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CHIBA101_1881	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CHIBA101_1882	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CHIBA101_1888	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CHIBA101_1892	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CHIBA101_1893	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CHIBA101_1894	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CHIBA101_1897	ENOG4108IUE	nitrate reductase beta subunit
CHIBA101_1898	ENOG4105R3A	Nitrate reductase
CHIBA101_1902	ENOG4105TVJ	transport system, permease
CHIBA101_1903	ENOG4105DQ5	transport system permease protein
CHIBA101_1904	ENOG4108MES	Periplasmic binding protein
CHIBA101_1905	ENOG4105E0A	ABC, transporter
CHIBA101_1906	ENOG4105E2A	Dehydrogenase
CHIBA101_1909	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CHIBA101_1910	ENOG4107TK4	histidinol-phosphate phosphatase
CHIBA101_1911	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CHIBA101_1912	ENOG4107RH8	nuclease SbcCD subunit D
CHIBA101_1913	ENOG4105EYH	Exonuclease
CHIBA101_1914	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CHIBA101_1915	ENOG4105CNN	ABC, transporter
CHIBA101_1916	ENOG4105C2J	ABC transporter
CHIBA101_1924	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CHIBA101_1925	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
CHIBA101_1927	ENOG4105BZU	Histidine kinase
CHIBA101_1928	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CHIBA101_1931	ENOG4108WQ6	secreted protein
CHIBA101_1932	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CHIBA101_1941	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
CHIBA101_1943	ENOG4105EIP	mannose-6-phosphate isomerase
CHIBA101_1946	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_1954	ENOG4106MCE	EamA-like transporter family
CHIBA101_1955	ENOG4105KPE	licD family
CHIBA101_1957	ENOG4108SHN	Glycosyl transferase, family 2
CHIBA101_1958	ENOG4105KPE	licD family
CHIBA101_1961	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CHIBA101_1966	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
CHIBA101_1969	ENOG4105EY8	ABC transporter
CHIBA101_1970	ENOG4105MFV	ABC-2 type transporter
CHIBA101_1972	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CHIBA101_1979	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CHIBA101_1982	ENOG4107XU6	Glycosyl transferase (Group 1
CHIBA101_1984	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CHIBA101_1994	ENOG4108KGH	TRANSCRIPTIONal
CHIBA101_1996	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CHIBA101_2001	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_2002	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_2003	ENOG4105BZU	Histidine kinase
CHIBA101_2004	ENOG4105CJ1	ABC, transporter
CHIBA101_2008	ENOG4105CMR	udp-glucose 4-epimerase
CHIBA101_2014	ENOG4105DQR	SNARE associated Golgi
CHIBA101_2016	ENOG4105BZU	Histidine kinase
CHIBA101_2017	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CHIBA101_2019	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CHIBA101_2020	ENOG4107WR6	Maf-like protein
CHIBA101_2023	ENOG4105WDJ	50S ribosomal protein L33
CHIBA101_2027	ENOG4108VPT	UPF0234 protein
CHIBA101_2029	ENOG4105D0M	Protease HtpX homolog
CHIBA101_2032	ENOG4105FDK	ABC transporter
CHIBA101_2033	ENOG4105CC5	ABC transporter
CHIBA101_2035	ENOG4105DSE	periplasmic solute binding protein
CHIBA101_2038	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CHIBA101_2040	ENOG4105D65	subunit l
CHIBA101_2041	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CHIBA101_2043	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CHIBA101_2044	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CHIBA101_2045	ENOG4108IEH	NADH dehydrogenase subunit g
CHIBA101_2046	ENOG4107QIZ	NADH dehydrogenase
CHIBA101_2048	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CHIBA101_2049	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CHIBA101_2050	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CHIBA101_2052	ENOG4105P52	geranylgeranyl reductase
CHIBA101_2053	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CHIBA101_2058	ENOG4108RH7	phosphoglycerate mutase
CHIBA101_2062	ENOG4108Z4U	Ferredoxin
CHIBA101_2065	ENOG4105CI3	gtp-binding protein typa
CHIBA101_2067	ENOG4105DEN	Luciferase family
CHIBA101_2068	ENOG4105VKD	bioY protein
CHIBA101_2072	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CHIBA101_2073	ENOG4105K5B	UPF0225 protein
CHIBA101_2074	ENOG4105DFM	M18 family aminopeptidase
CHIBA101_2076	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CHIBA101_2077	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CHIBA101_2078	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_2087	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
CHIBA101_2097	ENOG4106178	UPF0339 protein
CHIBA101_2104	ENOG4105C3G	gtp-binding protein
CHIBA101_2107	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CHIBA101_2108	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CHIBA101_2109	ENOG4108HKT	sucrose-6-phosphate hydrolase
CHIBA101_2110	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CHIBA101_2111	ENOG4105D7K	pfkb domain protein
CHIBA101_2112	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CHIBA101_2114	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CHIBA101_2115	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CHIBA101_2119	ENOG4108YYH	Nadph-dependent fmn reductase
CHIBA101_2120	ENOG4108YYH	Nadph-dependent fmn reductase
CHIBA101_2122	ENOG4105C7B	Threonine dehydratase
CHIBA101_2123	ENOG4105C01	Dihydroxy-acid dehydratase
CHIBA101_2124	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
CHIBA101_2125	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CHIBA101_2127	ENOG4105CJ1	ABC, transporter
CHIBA101_2129	ENOG4105BZU	Histidine kinase
CHIBA101_2130	ENOG4105CJ1	ABC, transporter
CHIBA101_2132	ENOG4105WH1	Two component transcriptional regulator luxr family
CHIBA101_2133	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CHIBA101_2134	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CHIBA101_2137	ENOG4105FF2	Type I DHQase
CHIBA101_2141	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CHIBA101_2146	ENOG4107G87	m6 family metalloprotease domain protein
CHIBA101_2147	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CHIBA101_2148	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CHIBA101_2162	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CHIBA101_2166	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CHIBA101_2169	ENOG41067SE	Tetr family transcriptional regulator
CHIBA101_2175	ENOG4105D9P	serine threonine protein kinase
CHIBA101_2177	ENOG4105C5H	ABC transporter
CHIBA101_2178	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CHIBA101_2179	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CHIBA101_2181	ENOG4105MS9	Resuscitation-promoting factor
CHIBA101_2184	ENOG4105F8V	Hydrolase, tatD family
CHIBA101_2185	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CHIBA101_2195	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
CHIBA101_2198	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CHIBA101_2207	ENOG4105C7N	Xanthine uracil vitamin C permease
CHIBA101_2208	ENOG4105C5I	Dehydrogenase
CHIBA101_2212	ENOG4105CFI	type iii restriction protein res subunit
CHIBA101_2218	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CHIBA101_2219	ENOG4105EB3	Histidine kinase
CHIBA101_2222	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CHIBA101_2225	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CHIBA101_2227	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CHIBA101_2234	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CHIBA101_2235	ENOG4105C8N	cysteinyl-tRNA synthetase
CHIBA101_2236	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CHIBA101_2237	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
CHIBA101_2240	ENOG4105FDK	ABC transporter
CHIBA101_2247	ENOG4105F3R	pts system mannose fructose sorbose family iid
CHIBA101_2248	ENOG4105ETZ	PTS System
CHIBA101_2249	ENOG4108EQA	pts system
CHIBA101_2251	ENOG4108HKT	sucrose-6-phosphate hydrolase
CHIBA101_2253	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_2254	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CHIBA101_2256	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CHIBA101_2264	ENOG4105CRK	lysyL-tRNA synthetase
CHIBA101_2266	ENOG4105KNI	merR family transcriptional Regulator
CHIBA101_2267	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CHIBA101_2268	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHIBA101_2269	ENOG4105CFG	Acts as a chaperone (By similarity)
CHIBA101_2272	ENOG4105C2W	permease
CHIBA101_2276	ENOG4105CQ7	ATP-dependent helicase
CHIBA101_2279	ENOG4108UW5	maltose o-acetyltransferase
CHIBA101_2280	ENOG4108Z6B	deaminase
CHIBA101_2281	ENOG4105C94	Transporter
CHIBA101_2282	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CHIBA101_2300	ENOG4105EC2	ftsk spoIIIe
CHIBA101_2307	ENOG4105D01	(LipO)protein
CHIBA101_2308	ENOG4108UMI	ABC transporter, permease
CHIBA101_2309	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CHIBA101_2311	ENOG4105KJF	protein tyrosine phosphatase
CHIBA101_2313	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
CHIBA101_2315	ENOG4107RM1	amidohydrolase
CHIBA101_2316	ENOG4108RVA	ribokinase
CHIBA101_2323	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CHIBA101_2324	ENOG4105CT4	transporter
CHIBA101_2325	ENOG4105CNT	hydrolase family 2
CHIBA101_2326	ENOG4105ETE	Transcriptional regulator (LacI family
CHIBA101_2327	ENOG4105DBI	uridine monophosphokinase
CHIBA101_2332	ENOG4105C09	Bile acid
CHIBA101_2334	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CHIBA101_2335	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
CHIBA101_2341	ENOG4105CG3	alpha amylase, catalytic region
CHIBA101_2346	ENOG4107QW3	Sucrose phosphorylase
CHIBA101_2349	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CHIBA101_2352	ENOG4105DSF	transport protein
CHIBA101_2353	ENOG4105EV9	Alpha Beta Hydrolase
CHIBA101_2354	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CHIBA101_2356	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CHIBA101_2358	ENOG4105DWF	phosphomethylpyrimidine kinase
CHIBA101_2360	ENOG4107WGA	YidE YbjL
CHIBA101_2365	ENOG4105C85	amino acid
CHIBA101_2367	ENOG41085J0	Protein CrcB homolog
CHIBA101_2368	ENOG41083TI	Protein CrcB homolog
CHIBA101_2370	ENOG4105DKQ	ROK family
CHIBA101_2372	ENOG4105DQ5	transport system permease protein
CHIBA101_2373	ENOG4105TVJ	transport system, permease
CHIBA101_2374	ENOG4105E0A	ABC, transporter
CHIBA101_2376	ENOG4105CDU	Replicative dna helicase
CHIBA101_2378	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CHIBA101_2379	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CHIBA101_2380	ENOG4107YH6	single-stranded DNA-binding protein
CHIBA101_2381	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
CHIBA101_2382	ENOG4105BZ4	penicillin-binding protein
CHIBA101_2385	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CHIBA101_2386	ENOG41060W2	glyoxylate carboligase
CHIBA101_2388	ENOG4108IUS	Transketolase
CHIBA101_2389	ENOG4108HHA	Transketolase
CHIBA101_2391	ENOG4105CXT	aspartate transcarbamylase
CHIBA101_2393	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CHIBA101_2395	ENOG410633P	Hydantoin racemase
CHIBA101_2399	ENOG4108JQ1	Dehydrogenase
CHIBA101_2400	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CHIBA101_2401	ENOG4105VT3	DNA binding domain protein, excisionase family
CHIBA101_2406	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CHIBA101_2410	ENOG4105C3M	thioredoxin reductase
CHIBA101_2411	ENOG4105K63	Thioredoxin
CHIBA101_2413	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CHIBA101_2414	ENOG4105CPF	Cell wall formation (By similarity)
CHIBA101_2416	ENOG4107QJE	Chromosome Partitioning Protein
CHIBA101_2417	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CHIBA101_2419	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CHIBA101_2420	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CHIBA101_2422	ENOG41084CH	50S ribosomal protein l34
CHIBA101_2423	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
