locus-tag	class	description
CHIBA101_0001	COG0592	DNA-directed DNA polymerase activity
CHIBA101_0002	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHIBA101_0003	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CHIBA101_0004	COG0187	DNA topoisomerase II activity
CHIBA101_0005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHIBA101_0016	COG3764	Sortase (surface protein transpeptidase)
CHIBA101_0019	COG0515	serine threonine protein kinase
CHIBA101_0020	COG0768	penicillin binding
CHIBA101_0023	COG1716	ATPase activity
CHIBA101_0024	COG1716	ATPase activity
CHIBA101_0028	COG1966	Carbon starvation protein
CHIBA101_0030	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CHIBA101_0032	COG2197	response regulator
CHIBA101_0041	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHIBA101_0042	COG1950	PFAM Membrane protein of
CHIBA101_0047	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHIBA101_0053	COG3842	ATPase activity
CHIBA101_0054	COG1178	ABC-type Fe3 transport system permease component
CHIBA101_0055	COG1840	ABC-type Fe3 transport system, periplasmic component
CHIBA101_0057	COG5002	protein histidine kinase activity
CHIBA101_0058	COG3588	fructose-bisphosphate aldolase
CHIBA101_0068	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHIBA101_0069	COG0561	phosphatase activity
CHIBA101_0090	COG0300	oxidoreductase activity
CHIBA101_0093	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHIBA101_0095	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHIBA101_0102	COG0626	cystathionine gamma-synthase activity
CHIBA101_0111	COG2197	response regulator
CHIBA101_0113	COG1131	(ABC) transporter
CHIBA101_0116	COG0247	lactate metabolic process
CHIBA101_0116	COG2181	nitrate reductase activity
CHIBA101_0121	COG3842	ATPase activity
CHIBA101_0131	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHIBA101_0136	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CHIBA101_0136	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CHIBA101_0138	COG1733	regulation of RNA biosynthetic process
CHIBA101_0144	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CHIBA101_0147	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHIBA101_0147	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHIBA101_0148	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHIBA101_0151	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHIBA101_0154	COG2205	protein histidine kinase activity
CHIBA101_0157	COG1695	Transcriptional regulator
CHIBA101_0164	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHIBA101_0171	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHIBA101_0172	COG0113	porphobilinogen synthase activity
CHIBA101_0174	COG0181	hydroxymethylbilane synthase activity
CHIBA101_0176	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHIBA101_0177	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHIBA101_0180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHIBA101_0181	COG0783	Belongs to the Dps family
CHIBA101_0185	COG1309	transcriptional regulator
CHIBA101_0186	COG1131	(ABC) transporter
CHIBA101_0208	COG1674	ftsk spoiiie
CHIBA101_0212	COG0366	Alpha amylase catalytic
CHIBA101_0216	COG1051	belongs to the nudix hydrolase family
CHIBA101_0217	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_0218	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_0219	COG1121	(ABC) transporter
CHIBA101_0220	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHIBA101_0223	COG1918	ferrous iron import across plasma membrane
CHIBA101_0223	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHIBA101_0226	COG1597	lipid kinase activity
CHIBA101_0229	COG1028	Short-chain dehydrogenase reductase Sdr
CHIBA101_0231	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHIBA101_0234	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHIBA101_0237	COG0596	Alpha beta hydrolase
CHIBA101_0239	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHIBA101_0249	COG0450	alkyl hydroperoxide reductase
CHIBA101_0255	COG2205	protein histidine kinase activity
CHIBA101_0256	COG0745	RESPONSE REGULATOR receiver
CHIBA101_0259	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHIBA101_0259	COG1754	DNA topoisomerase type I activity
CHIBA101_0265	COG0549	Belongs to the carbamate kinase family
CHIBA101_0266	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHIBA101_0267	COG2235	arginine
CHIBA101_0268	COG0745	RESPONSE REGULATOR receiver
CHIBA101_0269	COG2205	protein histidine kinase activity
CHIBA101_0273	COG0470	DNA polymerase III
CHIBA101_0277	COG0252	asparaginase activity
CHIBA101_0278	COG1113	amino acid transport
CHIBA101_0282	COG0588	phosphoglycerate mutase activity
CHIBA101_0284	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHIBA101_0286	COG0393	Putative heavy-metal-binding
CHIBA101_0289	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHIBA101_0291	COG1643	Atp-dependent helicase
CHIBA101_0291	COG1643	Atp-dependent helicase
CHIBA101_0296	COG3142	Participates in the control of copper homeostasis
CHIBA101_0297	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHIBA101_0298	COG2860	membrane
CHIBA101_0306	COG0631	protein serine/threonine phosphatase activity
CHIBA101_0312	COG0714	Associated with various cellular activities
CHIBA101_0323	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHIBA101_0327	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHIBA101_0332	COG0717	Belongs to the dCTP deaminase family
CHIBA101_0335	COG2176	DNA-directed DNA polymerase activity
CHIBA101_0337	COG0778	Nitroreductase
CHIBA101_0340	COG4221	oxidoreductase activity
CHIBA101_0342	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHIBA101_0343	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHIBA101_0344	COG0191	fructose-bisphosphate aldolase activity
CHIBA101_0351	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHIBA101_0356	COG0151	Belongs to the GarS family
CHIBA101_0357	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHIBA101_0360	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHIBA101_0361	COG0047	phosphoribosylformylglycinamidine synthase activity
CHIBA101_0362	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_0363	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHIBA101_0371	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHIBA101_0372	COG1349	DNA-binding transcription factor activity
CHIBA101_0373	COG1105	Belongs to the carbohydrate kinase PfkB family
CHIBA101_0374	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHIBA101_0374	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHIBA101_0377	COG2188	Transcriptional regulator
CHIBA101_0379	COG2084	Dehydrogenase
CHIBA101_0380	COG2610	gluconate transmembrane transporter activity
CHIBA101_0382	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHIBA101_0388	COG1132	(ABC) transporter
CHIBA101_0389	COG1132	(ABC) transporter
CHIBA101_0390	COG0577	efflux transmembrane transporter activity
CHIBA101_0391	COG1136	(ABC) transporter
CHIBA101_0394	COG1472	Belongs to the glycosyl hydrolase 3 family
CHIBA101_0403	COG0437	4 iron, 4 sulfur cluster binding
CHIBA101_0404	COG0243	molybdopterin cofactor binding
CHIBA101_0407	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHIBA101_0411	COG0513	Belongs to the DEAD box helicase family
CHIBA101_0413	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHIBA101_0417	COG1846	Transcriptional regulator
CHIBA101_0418	COG1764	response to oxidative stress
CHIBA101_0422	COG3265	gluconokinase activity
CHIBA101_0428	COG0306	phosphate transporter
CHIBA101_0430	COG0745	RESPONSE REGULATOR receiver
CHIBA101_0433	COG3485	protocatechuate 3,4-dioxygenase
CHIBA101_0436	COG1490	D-aminoacyl-tRNA deacylase activity
CHIBA101_0438	COG1116	anion transmembrane transporter activity
CHIBA101_0438	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHIBA101_0442	COG0542	response to heat
CHIBA101_0443	COG0477	Major facilitator Superfamily
CHIBA101_0445	COG0297	glycogen (starch) synthase activity
CHIBA101_0445	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_0447	COG0574	Belongs to the PEP-utilizing enzyme family
CHIBA101_0447	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHIBA101_0448	COG0714	Associated with various cellular activities
CHIBA101_0459	COG1595	DNA-templated transcription, initiation
CHIBA101_0461	COG3477	response to acidic pH
CHIBA101_0462	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CHIBA101_0463	COG2235	arginine
CHIBA101_0466	COG4948	Mandelate Racemase Muconate Lactonizing
CHIBA101_0467	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CHIBA101_0471	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHIBA101_0472	COG2873	o-acetylhomoserine
CHIBA101_0474	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CHIBA101_0478	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHIBA101_0479	COG0302	gtp cyclohydrolase
CHIBA101_0481	COG2197	response regulator
CHIBA101_0482	COG1404	Belongs to the peptidase S8 family
CHIBA101_0485	COG1132	(ABC) transporter
CHIBA101_0492	COG0577	efflux transmembrane transporter activity
CHIBA101_0492	COG1136	(ABC) transporter
CHIBA101_0493	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHIBA101_0494	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHIBA101_0499	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHIBA101_0500	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CHIBA101_0502	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHIBA101_0504	COG3104	oligopeptide transport
CHIBA101_0507	COG2814	Major facilitator Superfamily
CHIBA101_0509	COG1556	Lactate utilization protein
CHIBA101_0510	COG1139	Iron-sulfur cluster binding protein
CHIBA101_0511	COG0247	lactate metabolic process
CHIBA101_0512	COG1620	l-lactate permease
CHIBA101_0513	COG2217	Heavy metal translocating P-type atpase
CHIBA101_0515	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHIBA101_0516	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHIBA101_0517	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHIBA101_0518	COG2390	Transcriptional regulator
CHIBA101_0520	COG0698	ribose 5-phosphate isomerase
CHIBA101_0522	COG0647	UMP catabolic process
CHIBA101_0523	COG1070	Carbohydrate kinase
CHIBA101_0526	COG2390	Transcriptional regulator
CHIBA101_0528	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CHIBA101_0532	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CHIBA101_0540	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CHIBA101_0546	COG1070	Carbohydrate kinase
CHIBA101_0547	COG2376	Dihydroxyacetone kinase
CHIBA101_0548	COG1461	Dihydroxyacetone kinase
CHIBA101_0549	COG2017	converts alpha-aldose to the beta-anomer
CHIBA101_0551	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHIBA101_0553	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHIBA101_0554	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CHIBA101_0558	COG0436	Aminotransferase
CHIBA101_0559	COG1937	Protein conserved in bacteria
CHIBA101_0560	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHIBA101_0565	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHIBA101_0567	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHIBA101_0568	COG0081	regulation of translation
CHIBA101_0569	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHIBA101_0570	COG0222	ribosome binding
CHIBA101_0582	COG0085	RNA polymerase activity
CHIBA101_0583	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHIBA101_0584	COG0714	Associated with various cellular activities
CHIBA101_0589	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHIBA101_0590	COG0049	tRNA binding
CHIBA101_0591	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHIBA101_0592	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHIBA101_0595	COG0051	transcription antitermination factor activity, RNA binding
CHIBA101_0597	COG0088	Forms part of the polypeptide exit tunnel
CHIBA101_0598	COG0089	rRNA binding
CHIBA101_0599	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHIBA101_0600	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHIBA101_0601	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHIBA101_0602	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHIBA101_0603	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHIBA101_0604	COG0255	Belongs to the universal ribosomal protein uL29 family
CHIBA101_0605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHIBA101_0607	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHIBA101_0608	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHIBA101_0609	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHIBA101_0610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHIBA101_0612	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHIBA101_0614	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHIBA101_0615	COG1841	ribosomal large subunit assembly
CHIBA101_0616	COG0200	Binds to the 23S rRNA
CHIBA101_0618	COG0563	adenylate kinase activity
CHIBA101_0619	COG0024	Methionine aminopeptidase
CHIBA101_0620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHIBA101_0621	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHIBA101_0622	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHIBA101_0623	COG0202	RNA polymerase activity
CHIBA101_0624	COG0203	ribosomal protein L17
CHIBA101_0628	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHIBA101_0629	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHIBA101_0631	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CHIBA101_0632	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CHIBA101_0633	COG1072	(Pantothenic acid kinase))
CHIBA101_0636	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHIBA101_0637	COG0802	atpase or kinase
CHIBA101_0642	COG1053	succinate dehydrogenase
CHIBA101_0643	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHIBA101_0646	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHIBA101_0648	COG2949	membrane
CHIBA101_0649	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHIBA101_0652	COG0516	GMP reductase activity
CHIBA101_0653	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHIBA101_0655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHIBA101_0658	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_0659	COG0673	inositol 2-dehydrogenase activity
CHIBA101_0660	COG1609	Transcriptional regulator
CHIBA101_0661	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_0662	COG2814	Major facilitator Superfamily
CHIBA101_0663	COG0673	inositol 2-dehydrogenase activity
CHIBA101_0664	COG1609	Transcriptional regulator
CHIBA101_0666	COG0673	inositol 2-dehydrogenase activity
CHIBA101_0667	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHIBA101_0671	COG3718	enzyme involved in inositol metabolism
CHIBA101_0672	COG3962	Belongs to the TPP enzyme family
CHIBA101_0673	COG1012	belongs to the aldehyde dehydrogenase family
CHIBA101_0675	COG0673	inositol 2-dehydrogenase activity
CHIBA101_0676	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_0677	COG2814	Major facilitator Superfamily
CHIBA101_0682	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHIBA101_0682	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_0687	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_0690	COG0667	Aldo Keto reductase
CHIBA101_0698	COG2197	response regulator
CHIBA101_0701	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHIBA101_0703	COG0356	it plays a direct role in the translocation of protons across the membrane
CHIBA101_0704	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHIBA101_0705	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHIBA101_0706	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHIBA101_0707	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHIBA101_0708	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHIBA101_0709	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHIBA101_0710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHIBA101_0715	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CHIBA101_0724	COG0754	glutathionylspermidine amidase activity
CHIBA101_0726	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHIBA101_0727	COG0254	rRNA binding
CHIBA101_0728	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHIBA101_0729	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHIBA101_0730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHIBA101_0732	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHIBA101_0733	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHIBA101_0735	COG0708	Exodeoxyribonuclease III
CHIBA101_0737	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CHIBA101_0742	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHIBA101_0743	COG1121	(ABC) transporter
CHIBA101_0744	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_0745	COG1321	iron dependent repressor
CHIBA101_0745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_0746	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHIBA101_0747	COG1611	Belongs to the LOG family
CHIBA101_0753	COG2239	Acts as a magnesium transporter
CHIBA101_0755	COG1230	cation diffusion facilitator family transporter
CHIBA101_0757	COG0006	proline dipeptidase activity
CHIBA101_0761	COG2095	MarC family integral membrane protein
CHIBA101_0762	COG0513	Belongs to the DEAD box helicase family
CHIBA101_0779	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHIBA101_0782	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CHIBA101_0783	COG1132	(ABC) transporter
CHIBA101_0785	COG0039	L-malate dehydrogenase activity
CHIBA101_0788	COG1725	Transcriptional regulator
CHIBA101_0793	COG0058	SHG alpha-glucan phosphorylase activity
CHIBA101_0794	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHIBA101_0818	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHIBA101_0821	COG0366	Alpha amylase catalytic
CHIBA101_0822	COG0180	Tryptophanyl-tRNA synthetase
CHIBA101_0825	COG2086	electron transfer activity
CHIBA101_0826	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHIBA101_0828	COG0482	sulfurtransferase activity
CHIBA101_0830	COG1518	maintenance of DNA repeat elements
CHIBA101_0833	COG1857	crispr-associated protein
CHIBA101_0837	COG2161	toxin-antitoxin pair type II binding
CHIBA101_0839	COG2390	Transcriptional regulator
CHIBA101_0840	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHIBA101_0841	COG0738	Major facilitator superfamily
CHIBA101_0843	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHIBA101_0847	COG1070	Carbohydrate kinase
CHIBA101_0851	COG1615	UPF0182 protein
CHIBA101_0853	COG4585	Histidine kinase
CHIBA101_0854	COG2197	response regulator
CHIBA101_0855	COG0114	fumarate hydratase activity
CHIBA101_0863	COG0346	lactoylglutathione lyase activity
CHIBA101_0865	COG1695	Transcriptional regulator
CHIBA101_0866	COG1125	glycine betaine transport
CHIBA101_0866	COG0517	IMP dehydrogenase activity
CHIBA101_0870	COG1609	Transcriptional regulator
CHIBA101_0872	COG0673	inositol 2-dehydrogenase activity
CHIBA101_0874	COG2814	Major facilitator Superfamily
CHIBA101_0876	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHIBA101_0877	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHIBA101_0885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHIBA101_0887	COG4152	abc transporter atp-binding protein
CHIBA101_0889	COG1196	nuclear chromosome segregation
CHIBA101_0898	COG2197	response regulator
CHIBA101_0899	COG3851	Histidine kinase
CHIBA101_0902	COG1136	(ABC) transporter
CHIBA101_0902	COG0577	efflux transmembrane transporter activity
CHIBA101_0904	COG2197	response regulator
CHIBA101_0906	COG0789	Transcriptional regulator
CHIBA101_0908	COG2197	response regulator
CHIBA101_0909	COG4585	Histidine kinase
CHIBA101_0911	COG1131	(ABC) transporter
CHIBA101_0912	COG1115	amino acid carrier protein
CHIBA101_0913	COG0228	four-way junction DNA binding
CHIBA101_0914	COG1837	Belongs to the UPF0109 family
CHIBA101_0916	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHIBA101_0918	COG0681	Belongs to the peptidase S26 family
CHIBA101_0919	COG0335	large ribosomal subunit rRNA binding
CHIBA101_0920	COG0681	Belongs to the peptidase S26 family
CHIBA101_0921	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHIBA101_0923	COG0792	nuclease activity
CHIBA101_0924	COG0606	chelatase, subunit chli
CHIBA101_0926	COG4974	Belongs to the 'phage' integrase family
CHIBA101_0929	COG0052	Belongs to the universal ribosomal protein uS2 family
CHIBA101_0930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHIBA101_0934	COG0233	cytoplasmic translational termination
CHIBA101_0935	COG0575	Belongs to the CDS family
CHIBA101_0936	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHIBA101_0938	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHIBA101_0939	COG0750	zinc metalloprotease
CHIBA101_0940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHIBA101_0942	COG0442	prolyl-tRNA aminoacylation
CHIBA101_0944	COG0779	Required for maturation of 30S ribosomal subunits
CHIBA101_0947	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHIBA101_0947	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHIBA101_0952	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHIBA101_0953	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHIBA101_0960	COG1472	Belongs to the glycosyl hydrolase 3 family
CHIBA101_0961	COG1185	polyribonucleotide nucleotidyltransferase activity
CHIBA101_0962	COG0612	Peptidase, M16
CHIBA101_0963	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHIBA101_0966	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHIBA101_0967	COG0656	L-ascorbic acid biosynthetic process
CHIBA101_0968	COG0318	PFAM AMP-dependent synthetase and ligase
CHIBA101_0974	COG2001	Belongs to the MraZ family
CHIBA101_0975	COG0275	rRNA processing
CHIBA101_0977	COG0768	penicillin binding
CHIBA101_0978	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHIBA101_0979	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHIBA101_0980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHIBA101_0981	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHIBA101_0982	COG0772	Belongs to the SEDS family
CHIBA101_0983	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHIBA101_0984	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHIBA101_0986	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHIBA101_0988	COG1799	cell septum assembly
CHIBA101_0990	COG3599	regulation of cell shape
CHIBA101_0991	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHIBA101_0995	COG0587	DNA-directed DNA polymerase activity
CHIBA101_0996	COG2501	S4 domain
CHIBA101_1000	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHIBA101_1004	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHIBA101_1011	COG0025	NhaP-type Na H and K H
CHIBA101_1013	COG0131	Imidazoleglycerol-phosphate dehydratase
CHIBA101_1016	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHIBA101_1017	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHIBA101_1021	COG4868	Belongs to the UPF0371 family
CHIBA101_1022	COG0268	Binds directly to 16S ribosomal RNA
CHIBA101_1025	COG0159	tryptophan synthase activity
CHIBA101_1027	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHIBA101_1028	COG0512	Glutamine amidotransferase of anthranilate synthase
CHIBA101_1029	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHIBA101_1030	COG0133	tryptophan synthase activity
CHIBA101_1033	COG0481	GTPase activity
CHIBA101_1035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHIBA101_1036	COG2807	transmembrane transport
CHIBA101_1038	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHIBA101_1040	COG2271	Major facilitator Superfamily
CHIBA101_1042	COG1420	regulation of RNA biosynthetic process
CHIBA101_1043	COG0484	heat shock protein binding
CHIBA101_1045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHIBA101_1052	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHIBA101_1054	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHIBA101_1057	COG1476	TRANSCRIPTIONal
CHIBA101_1060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHIBA101_1061	COG1381	Involved in DNA repair and RecF pathway recombination
CHIBA101_1062	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHIBA101_1063	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CHIBA101_1064	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_1064	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHIBA101_1065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_1066	COG1121	(ABC) transporter
CHIBA101_1069	COG0423	glycine-tRNA ligase activity
CHIBA101_1074	COG0560	Phosphoserine phosphatase
CHIBA101_1076	COG0297	glycogen (starch) synthase activity
CHIBA101_1079	COG1119	ATPase activity
CHIBA101_1084	COG0488	(ABC) transporter
CHIBA101_1093	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHIBA101_1095	COG0515	serine threonine protein kinase
CHIBA101_1095	COG2815	serine threonine protein kinase
CHIBA101_1097	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHIBA101_1099	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CHIBA101_1100	COG0352	thiamine-phosphate diphosphorylase activity
CHIBA101_1101	COG0351	phosphomethylpyrimidine kinase
CHIBA101_1107	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHIBA101_1116	COG0569	domain protein
CHIBA101_1117	COG0531	amino acid
CHIBA101_1118	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHIBA101_1119	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CHIBA101_1120	COG1609	Transcriptional regulator
CHIBA101_1125	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHIBA101_1126	COG4221	oxidoreductase activity
CHIBA101_1127	COG1881	PFAM PEBP family protein
CHIBA101_1131	COG0833	amino acid
CHIBA101_1132	COG0587	DNA-directed DNA polymerase activity
CHIBA101_1134	COG0676	glucose-6-phosphate 1-epimerase activity
CHIBA101_1140	COG0477	Major facilitator Superfamily
CHIBA101_1142	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHIBA101_1144	COG0667	Aldo Keto reductase
CHIBA101_1146	COG2391	methyltransferase activity
CHIBA101_1149	COG1994	Peptidase M50
CHIBA101_1149	COG0517	IMP dehydrogenase activity
CHIBA101_1150	COG2814	Major facilitator Superfamily
CHIBA101_1151	COG1715	Restriction endonuclease
CHIBA101_1153	COG1222	aaa ATPase
CHIBA101_1156	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CHIBA101_1158	COG0107	imidazoleglycerol-phosphate synthase activity
CHIBA101_1163	COG1297	OPT oligopeptide transporter protein
CHIBA101_1164	COG0134	indole-3-glycerol-phosphate synthase activity
CHIBA101_1165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHIBA101_1169	COG2050	protein possibly involved in aromatic compounds catabolism
CHIBA101_1172	COG0539	negative regulation of cytoplasmic translation
CHIBA101_1174	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CHIBA101_1174	COG0237	dephospho-CoA kinase activity
CHIBA101_1176	COG0556	nucleotide-excision repair
CHIBA101_1181	COG0861	Integral membrane protein TerC family
CHIBA101_1183	COG2226	methyltransferase
CHIBA101_1187	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHIBA101_1188	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CHIBA101_1189	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CHIBA101_1195	COG0322	excinuclease ABC activity
CHIBA101_1196	COG2190	(PTS) system
CHIBA101_1196	COG1263	PTS System
CHIBA101_1196	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_1198	COG3711	transcriptional antiterminator
CHIBA101_1200	COG1660	Displays ATPase and GTPase activities
CHIBA101_1201	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CHIBA101_1202	COG1481	regulation of sporulation
CHIBA101_1203	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CHIBA101_1204	COG0126	phosphoglycerate kinase activity
CHIBA101_1205	COG0149	triose-phosphate isomerase activity
CHIBA101_1206	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHIBA101_1210	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHIBA101_1213	COG1160	GTP binding
CHIBA101_1214	COG2818	Glycosylase
CHIBA101_1216	COG0166	Belongs to the GPI family
CHIBA101_1230	COG4989	oxidoreductase activity
CHIBA101_1234	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CHIBA101_1236	COG1716	ATPase activity
CHIBA101_1240	COG0443	Heat shock 70 kDa protein
CHIBA101_1241	COG2190	(PTS) system
CHIBA101_1241	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_1241	COG1263	PTS System
CHIBA101_1245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHIBA101_1249	COG1216	Glycosyl transferase, family 2
CHIBA101_1252	COG0805	protein transport
CHIBA101_1253	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHIBA101_1271	COG0140	phosphoribosyl-ATP diphosphatase activity
CHIBA101_1272	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHIBA101_1273	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHIBA101_1274	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHIBA101_1276	COG1335	isochorismatase
CHIBA101_1278	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHIBA101_1279	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHIBA101_1280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHIBA101_1281	COG4770	biotin carboxylase activity
CHIBA101_1283	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHIBA101_1285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHIBA101_1289	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHIBA101_1291	COG1758	RNA polymerase activity
CHIBA101_1293	COG0194	GDP metabolic process
CHIBA101_1295	COG0284	orotidine-5'-phosphate decarboxylase activity
CHIBA101_1296	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHIBA101_1298	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHIBA101_1299	COG0540	Belongs to the ATCase OTCase family
CHIBA101_1300	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CHIBA101_1306	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_1307	COG1024	Enoyl-CoA hydratase
CHIBA101_1308	COG3425	synthase
CHIBA101_1310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_1310	COG0300	oxidoreductase activity
CHIBA101_1310	COG3321	synthase
CHIBA101_1310	COG4221	oxidoreductase activity
CHIBA101_1311	COG3321	synthase
CHIBA101_1311	COG1028	Short-chain dehydrogenase reductase Sdr
CHIBA101_1311	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHIBA101_1311	COG4221	oxidoreductase activity
CHIBA101_1312	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_1312	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_1312	COG3321	synthase
CHIBA101_1312	COG0300	oxidoreductase activity
CHIBA101_1312	COG4221	oxidoreductase activity
CHIBA101_1312	COG3321	synthase
CHIBA101_1312	COG0300	oxidoreductase activity
CHIBA101_1312	COG4221	oxidoreductase activity
CHIBA101_1313	COG0300	oxidoreductase activity
CHIBA101_1313	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_1313	COG4221	oxidoreductase activity
CHIBA101_1313	COG3321	synthase
CHIBA101_1315	COG1131	(ABC) transporter
CHIBA101_1316	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_1316	COG4221	oxidoreductase activity
CHIBA101_1316	COG3321	synthase
CHIBA101_1316	COG0300	oxidoreductase activity
CHIBA101_1317	COG1024	Enoyl-CoA hydratase
CHIBA101_1322	COG0745	RESPONSE REGULATOR receiver
CHIBA101_1326	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHIBA101_1327	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHIBA101_1329	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHIBA101_1331	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHIBA101_1332	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHIBA101_1334	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHIBA101_1336	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHIBA101_1337	COG0730	response to heat
CHIBA101_1339	COG2409	Drug exporters of the RND superfamily
CHIBA101_1340	COG0009	L-threonylcarbamoyladenylate synthase
CHIBA101_1341	COG0640	Transcriptional regulator
CHIBA101_1343	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHIBA101_1347	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHIBA101_1349	COG0124	histidyl-tRNA synthetase
CHIBA101_1353	COG1196	nuclear chromosome segregation
CHIBA101_1354	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHIBA101_1355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHIBA101_1356	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHIBA101_1357	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHIBA101_1359	COG2255	four-way junction helicase activity
CHIBA101_1360	COG0632	four-way junction helicase activity
CHIBA101_1361	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CHIBA101_1362	COG0217	transcriptional regulatory protein
CHIBA101_1363	COG0494	nUDIX hydrolase
CHIBA101_1366	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_1367	COG1560	Kdo2-lipid A biosynthetic process
CHIBA101_1370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHIBA101_1372	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHIBA101_1384	COG1882	Formate acetyltransferase
CHIBA101_1387	COG0038	chloride channel
CHIBA101_1389	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHIBA101_1390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHIBA101_1391	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHIBA101_1393	COG0321	lipoyl(octanoyl) transferase activity
CHIBA101_1394	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHIBA101_1398	COG0765	amino acid transport
CHIBA101_1401	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CHIBA101_1402	COG0174	glutamine synthetase
CHIBA101_1403	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHIBA101_1407	COG3022	response to hydroperoxide
CHIBA101_1409	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHIBA101_1411	COG0504	CTP synthase activity
CHIBA101_1422	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CHIBA101_1423	COG1027	Aspartate ammonia-lyase
CHIBA101_1425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_1433	COG0358	DNA primase activity
CHIBA101_1437	COG1175	transmembrane transport
CHIBA101_1438	COG3833	ABC-type maltose transport systems, permease component
CHIBA101_1441	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHIBA101_1443	COG0667	Aldo Keto reductase
CHIBA101_1444	COG0167	dihydroorotate dehydrogenase activity
CHIBA101_1447	COG0575	Belongs to the CDS family
CHIBA101_1449	COG3189	MarR family transcriptional regulator
CHIBA101_1451	COG1131	(ABC) transporter
CHIBA101_1454	COG2151	metal-sulfur cluster biosynthetic enzyme
CHIBA101_1455	COG0822	iron-sulfur transferase activity
CHIBA101_1457	COG0396	ATPase activity
CHIBA101_1459	COG0719	Fe-S assembly protein
CHIBA101_1462	COG0483	inositol monophosphate 1-phosphatase activity
CHIBA101_1468	COG1136	(ABC) transporter
CHIBA101_1472	COG0497	DNA recombination
CHIBA101_1473	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHIBA101_1476	COG0647	UMP catabolic process
CHIBA101_1481	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHIBA101_1483	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHIBA101_1484	COG2094	Belongs to the DNA glycosylase MPG family
CHIBA101_1485	COG0165	Argininosuccinate lyase
CHIBA101_1487	COG0137	argininosuccinate synthase activity
CHIBA101_1489	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHIBA101_1490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHIBA101_1492	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHIBA101_1497	COG0765	amino acid transport
CHIBA101_1498	COG0765	amino acid transport
CHIBA101_1499	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHIBA101_1500	COG1126	abc transporter atp-binding protein
CHIBA101_1501	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHIBA101_1502	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHIBA101_1503	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHIBA101_1504	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHIBA101_1506	COG4133	protoheme IX ABC transporter activity
CHIBA101_1510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHIBA101_1513	COG1307	EDD domain protein, DegV family
CHIBA101_1514	COG0433	COG0433 Predicted ATPase
CHIBA101_1515	COG0495	leucyl-tRNA aminoacylation
CHIBA101_1516	COG0537	adenosine 5'-monophosphoramidase activity
CHIBA101_1522	COG0733	neurotransmitter:sodium symporter activity
CHIBA101_1530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHIBA101_1531	COG1349	DNA-binding transcription factor activity
CHIBA101_1532	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHIBA101_1534	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHIBA101_1535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHIBA101_1536	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHIBA101_1537	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHIBA101_1539	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHIBA101_1541	COG0785	Cytochrome C biogenesis protein
CHIBA101_1544	COG3005	denitrification pathway
CHIBA101_1545	COG1530	ribonuclease E activity
CHIBA101_1546	COG1271	oxidase subunit
CHIBA101_1547	COG1294	oxidase, subunit
CHIBA101_1548	COG4988	ABC transporter
CHIBA101_1549	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHIBA101_1552	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHIBA101_1553	COG0571	ribonuclease III activity
CHIBA101_1556	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHIBA101_1561	COG1461	Dihydroxyacetone kinase
CHIBA101_1562	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHIBA101_1564	COG2885	chlorophyll binding
CHIBA101_1566	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHIBA101_1569	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHIBA101_1571	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHIBA101_1572	COG0066	3-isopropylmalate dehydratase activity
CHIBA101_1573	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHIBA101_1578	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHIBA101_1580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHIBA101_1583	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHIBA101_1585	COG2813	Specifically methylates the guanine in position
CHIBA101_1587	COG1114	Component of the transport system for branched-chain amino acids
CHIBA101_1588	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHIBA101_1589	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHIBA101_1594	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHIBA101_1595	COG1940	carbohydrate kinase activity
CHIBA101_1595	COG1846	Transcriptional regulator
CHIBA101_1598	COG0395	ABC-type sugar transport system, permease component
CHIBA101_1600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHIBA101_1601	COG2137	regulation of response to DNA damage stimulus
CHIBA101_1602	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHIBA101_1604	COG1396	sequence-specific DNA binding
CHIBA101_1605	COG1058	Belongs to the CinA family
CHIBA101_1605	COG1546	Belongs to the CinA family
CHIBA101_1608	COG1674	ftsk spoiiie
CHIBA101_1619	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHIBA101_1624	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHIBA101_1625	COG1115	amino acid carrier protein
CHIBA101_1626	COG1115	amino acid carrier protein
CHIBA101_1627	COG1115	amino acid carrier protein
CHIBA101_1628	COG1115	amino acid carrier protein
CHIBA101_1633	COG2040	homocysteine
CHIBA101_1634	COG0833	amino acid
CHIBA101_1635	COG3304	Inner membrane component domain
CHIBA101_1646	COG1126	abc transporter atp-binding protein
CHIBA101_1650	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CHIBA101_1651	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHIBA101_1653	COG1234	tRNA 3'-trailer cleavage
CHIBA101_1654	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHIBA101_1656	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CHIBA101_1660	COG0363	glucosamine-6-phosphate deaminase activity
CHIBA101_1662	COG1131	(ABC) transporter
CHIBA101_1664	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CHIBA101_1665	COG1940	carbohydrate kinase activity
CHIBA101_1668	COG4608	Belongs to the ABC transporter superfamily
CHIBA101_1669	COG0444	Belongs to the ABC transporter superfamily
CHIBA101_1671	COG4166	transmembrane transport
CHIBA101_1672	COG2188	Transcriptional regulator
CHIBA101_1673	COG2233	PERMEase
CHIBA101_1676	COG2177	Part of the ABC transporter FtsEX involved in
CHIBA101_1677	COG2884	Cell division ATP-binding protein ftsE
CHIBA101_1683	COG1716	ATPase activity
CHIBA101_1683	COG1131	(ABC) transporter
CHIBA101_1683	COG0842	Transport permease protein
CHIBA101_1684	COG0515	serine threonine protein kinase
CHIBA101_1685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CHIBA101_1689	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHIBA101_1690	COG1086	Polysaccharide biosynthesis protein
CHIBA101_1691	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHIBA101_1700	COG1216	Glycosyl transferase, family 2
CHIBA101_1701	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHIBA101_1702	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHIBA101_1703	COG1316	TRANSCRIPTIONal
CHIBA101_1704	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CHIBA101_1704	COG0463	Glycosyl transferase, family 2
CHIBA101_1705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHIBA101_1706	COG0473	3-isopropylmalate dehydrogenase activity
CHIBA101_1707	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHIBA101_1710	COG2985	domain, Protein
CHIBA101_1710	COG0569	domain protein
CHIBA101_1712	COG1609	Transcriptional regulator
CHIBA101_1713	COG5492	domain, Protein
CHIBA101_1713	COG1621	beta-fructofuranosidase activity
CHIBA101_1713	COG3583	domain protein
CHIBA101_1714	COG0395	ABC-type sugar transport system, permease component
CHIBA101_1715	COG1175	transmembrane transport
CHIBA101_1719	COG3547	Transposase (IS116 IS110 IS902 family)
CHIBA101_1724	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHIBA101_1725	COG0154	amidase activity
CHIBA101_1726	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHIBA101_1728	COG0105	UTP biosynthetic process
CHIBA101_1729	COG0285	dihydrofolate synthase activity
CHIBA101_1730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHIBA101_1731	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHIBA101_1732	COG0489	protein tyrosine kinase activity
CHIBA101_1734	COG0110	maltose O-acetyltransferase activity
CHIBA101_1736	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_1738	COG1215	transferase activity, transferring glycosyl groups
CHIBA101_1741	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHIBA101_1742	COG0175	sulfate reduction
CHIBA101_1745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHIBA101_1745	COG1648	precorrin-2 dehydrogenase activity
CHIBA101_1746	COG0730	response to heat
CHIBA101_1749	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHIBA101_1750	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CHIBA101_1752	COG4122	O-methyltransferase activity
CHIBA101_1753	COG1222	aaa ATPase
CHIBA101_1757	COG1605	Chorismate mutase
CHIBA101_1757	COG0287	Prephenate dehydrogenase
CHIBA101_1758	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHIBA101_1759	COG0740	serine-type endopeptidase activity
CHIBA101_1761	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHIBA101_1766	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHIBA101_1770	COG0464	growth
CHIBA101_1774	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHIBA101_1783	COG1201	RNA secondary structure unwinding
CHIBA101_1794	COG0778	Nitroreductase
CHIBA101_1799	COG1739	Uncharacterized protein family UPF0029
CHIBA101_1801	COG1045	serine acetyltransferase
CHIBA101_1803	COG1929	Belongs to the glycerate kinase type-1 family
CHIBA101_1804	COG0698	ribose 5-phosphate isomerase
CHIBA101_1806	COG3590	peptidase
CHIBA101_1810	COG2188	Transcriptional regulator
CHIBA101_1813	COG2190	(PTS) system
CHIBA101_1815	COG2190	(PTS) system
CHIBA101_1815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_1815	COG1263	PTS System
CHIBA101_1816	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHIBA101_1817	COG1946	Acyl-CoA thioesterase
CHIBA101_1821	COG0045	succinate-CoA ligase (ADP-forming) activity
CHIBA101_1822	COG0205	6-phosphofructokinase activity
CHIBA101_1826	COG2885	chlorophyll binding
CHIBA101_1835	COG1609	Transcriptional regulator
CHIBA101_1836	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_1837	COG0673	inositol 2-dehydrogenase activity
CHIBA101_1842	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHIBA101_1843	COG0254	rRNA binding
CHIBA101_1848	COG0701	Predicted permease
CHIBA101_1850	COG0083	homoserine kinase activity
CHIBA101_1851	COG0460	homoserine dehydrogenase
CHIBA101_1853	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHIBA101_1854	COG0019	diaminopimelate decarboxylase activity
CHIBA101_1855	COG0018	arginyl-trna synthetase
CHIBA101_1858	COG0584	glycerophosphoryl diester phosphodiesterase
CHIBA101_1861	COG1253	flavin adenine dinucleotide binding
CHIBA101_1862	COG0567	Dehydrogenase, E1 component
CHIBA101_1862	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHIBA101_1866	COG5662	AntiSigma factor
CHIBA101_1867	COG1595	DNA-templated transcription, initiation
CHIBA101_1868	COG1695	Transcriptional regulator
CHIBA101_1871	COG1131	(ABC) transporter
CHIBA101_1874	COG3547	Transposase (IS116 IS110 IS902 family)
CHIBA101_1877	COG2838	Isocitrate dehydrogenase
CHIBA101_1878	COG1487	ribonuclease activity
CHIBA101_1880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHIBA101_1881	COG1162	GTPase activity
CHIBA101_1882	COG0456	acetyltransferase
CHIBA101_1888	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHIBA101_1890	COG0314	molybdopterin synthase activity
CHIBA101_1892	COG0315	cyclic pyranopterin monophosphate synthase activity
CHIBA101_1893	COG0746	molybdenum cofactor guanylyltransferase activity
CHIBA101_1894	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHIBA101_1894	COG0315	cyclic pyranopterin monophosphate synthase activity
CHIBA101_1897	COG1140	nitrate reductase beta subunit
CHIBA101_1898	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CHIBA101_1902	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_1903	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_1904	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHIBA101_1905	COG1120	ATPase activity
CHIBA101_1906	COG1063	alcohol dehydrogenase
CHIBA101_1909	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHIBA101_1910	COG0483	inositol monophosphate 1-phosphatase activity
CHIBA101_1911	COG1968	undecaprenyl-diphosphatase activity
CHIBA101_1912	COG0420	3'-5' exonuclease activity
CHIBA101_1913	COG0419	ATPase involved in DNA repair
CHIBA101_1914	COG1879	ABC-type sugar transport system periplasmic component
CHIBA101_1915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHIBA101_1916	COG1129	ABC transporter
CHIBA101_1924	COG0653	protein targeting
CHIBA101_1925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHIBA101_1927	COG5000	phosphorelay sensor kinase activity
CHIBA101_1927	COG5002	protein histidine kinase activity
CHIBA101_1928	COG0745	RESPONSE REGULATOR receiver
CHIBA101_1932	COG0714	Associated with various cellular activities
CHIBA101_1946	COG2197	response regulator
CHIBA101_1952	COG1131	(ABC) transporter
CHIBA101_1953	COG4750	Nucleotidyl transferase
CHIBA101_1954	COG0697	spore germination
CHIBA101_1955	COG3475	LICD family
CHIBA101_1957	COG1215	transferase activity, transferring glycosyl groups
CHIBA101_1958	COG3475	LICD family
CHIBA101_1961	COG1216	Glycosyl transferase, family 2
CHIBA101_1966	COG3754	Rhamnan synthesis protein F
CHIBA101_1972	COG1088	dTDP-glucose 4,6-dehydratase activity
CHIBA101_1982	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_1984	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHIBA101_1984	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_1994	COG1316	TRANSCRIPTIONal
CHIBA101_1995	COG0395	ABC-type sugar transport system, permease component
CHIBA101_2002	COG2197	response regulator
CHIBA101_2003	COG4585	Histidine kinase
CHIBA101_2004	COG1131	(ABC) transporter
CHIBA101_2008	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHIBA101_2014	COG0586	Pfam SNARE associated Golgi protein
CHIBA101_2016	COG5002	protein histidine kinase activity
CHIBA101_2017	COG0745	RESPONSE REGULATOR receiver
CHIBA101_2019	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHIBA101_2019	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHIBA101_2020	COG0424	maF-like protein
CHIBA101_2023	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHIBA101_2027	COG1666	GTP binding
CHIBA101_2029	COG0501	Belongs to the peptidase M48B family
CHIBA101_2032	COG1121	(ABC) transporter
CHIBA101_2038	COG1007	ATP synthesis coupled electron transport
CHIBA101_2040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHIBA101_2041	COG0713	ATP synthesis coupled electron transport
CHIBA101_2044	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHIBA101_2045	COG1034	ATP synthesis coupled electron transport
CHIBA101_2046	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CHIBA101_2048	COG0649	NAD binding
CHIBA101_2049	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHIBA101_2050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHIBA101_2052	COG0644	oxidoreductase
CHIBA101_2053	COG2226	methyltransferase
CHIBA101_2058	COG0406	alpha-ribazole phosphatase activity
CHIBA101_2067	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHIBA101_2068	COG1268	BioY protein
CHIBA101_2072	COG1902	pentaerythritol trinitrate reductase activity
CHIBA101_2073	COG3012	SEC-C Motif Domain Protein
CHIBA101_2074	COG1362	aminopeptidase activity
CHIBA101_2076	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHIBA101_2077	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHIBA101_2087	COG0596	Alpha beta hydrolase
CHIBA101_2097	COG3422	double-strand break repair
CHIBA101_2102	COG1061	Type III restriction enzyme res subunit
CHIBA101_2104	COG0012	GTP binding
CHIBA101_2106	COG1322	Protein conserved in bacteria
CHIBA101_2107	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHIBA101_2108	COG1570	exodeoxyribonuclease VII activity
CHIBA101_2109	COG1621	beta-fructofuranosidase activity
CHIBA101_2110	COG1722	exodeoxyribonuclease VII activity
CHIBA101_2112	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHIBA101_2114	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHIBA101_2115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHIBA101_2119	COG0431	NADPH-dependent FMN reductase
CHIBA101_2120	COG0431	NADPH-dependent FMN reductase
CHIBA101_2122	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHIBA101_2124	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHIBA101_2125	COG0545	Peptidyl-prolyl cis-trans isomerase
CHIBA101_2127	COG1131	(ABC) transporter
CHIBA101_2130	COG1131	(ABC) transporter
CHIBA101_2132	COG2197	response regulator
CHIBA101_2133	COG0193	aminoacyl-tRNA hydrolase activity
CHIBA101_2134	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHIBA101_2136	COG1487	ribonuclease activity
CHIBA101_2137	COG0710	3-dehydroquinate dehydratase activity
CHIBA101_2141	COG0148	phosphopyruvate hydratase activity
CHIBA101_2146	COG3291	Pkd domain containing protein
CHIBA101_2146	COG4412	M6 family metalloprotease domain protein
CHIBA101_2148	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHIBA101_2162	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_2166	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHIBA101_2166	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CHIBA101_2169	COG1309	transcriptional regulator
CHIBA101_2175	COG0515	serine threonine protein kinase
CHIBA101_2175	COG2815	serine threonine protein kinase
CHIBA101_2177	COG0488	(ABC) transporter
CHIBA101_2178	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CHIBA101_2179	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHIBA101_2181	COG1652	LysM domain
CHIBA101_2184	COG0084	hydrolase, TatD family'
CHIBA101_2185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHIBA101_2195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHIBA101_2198	COG1970	mechanosensitive ion channel activity
CHIBA101_2203	COG3103	Sh3 type 3 domain protein
CHIBA101_2203	COG1388	LysM domain
CHIBA101_2203	COG0791	NLP P60 protein
CHIBA101_2207	COG2252	PERMEase
CHIBA101_2212	COG1061	Type III restriction enzyme res subunit
CHIBA101_2216	COG1842	Phage shock protein A
CHIBA101_2218	COG0745	RESPONSE REGULATOR receiver
CHIBA101_2219	COG2205	protein histidine kinase activity
CHIBA101_2222	COG0459	protein refolding
CHIBA101_2225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHIBA101_2227	COG2890	protein-(glutamine-N5) methyltransferase activity
CHIBA101_2231	COG3842	ATPase activity
CHIBA101_2235	COG0215	cysteine-tRNA ligase activity
CHIBA101_2236	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHIBA101_2237	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHIBA101_2247	COG3716	PTS system mannose fructose sorbose family IID component
CHIBA101_2248	COG3715	PTS system
CHIBA101_2249	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_2249	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHIBA101_2251	COG1621	beta-fructofuranosidase activity
CHIBA101_2266	COG0789	Transcriptional regulator
CHIBA101_2267	COG0484	heat shock protein binding
CHIBA101_2268	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHIBA101_2269	COG0443	Heat shock 70 kDa protein
CHIBA101_2272	COG2233	PERMEase
CHIBA101_2276	COG1643	Atp-dependent helicase
CHIBA101_2279	COG0110	maltose O-acetyltransferase activity
CHIBA101_2280	COG0590	tRNA wobble adenosine to inosine editing
CHIBA101_2281	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHIBA101_2282	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHIBA101_2307	COG1464	Belongs to the NlpA lipoprotein family
CHIBA101_2308	COG2011	ABC-type metal ion transport system permease component
CHIBA101_2311	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHIBA101_2313	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHIBA101_2315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CHIBA101_2315	COG1473	amidohydrolase
CHIBA101_2316	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHIBA101_2318	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHIBA101_2323	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHIBA101_2324	COG2211	Major facilitator Superfamily
CHIBA101_2326	COG1609	Transcriptional regulator
CHIBA101_2327	COG0572	uridine kinase
CHIBA101_2332	COG0385	Bile acid
CHIBA101_2334	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHIBA101_2335	COG1780	Probably involved in ribonucleotide reductase function
CHIBA101_2341	COG0366	Alpha amylase catalytic
CHIBA101_2349	COG1196	nuclear chromosome segregation
CHIBA101_2352	COG0628	permease
CHIBA101_2353	COG0596	Alpha beta hydrolase
CHIBA101_2354	COG1854	S-ribosylhomocysteine lyase activity
CHIBA101_2356	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHIBA101_2358	COG0351	phosphomethylpyrimidine kinase
CHIBA101_2360	COG0569	domain protein
CHIBA101_2360	COG2985	domain, Protein
CHIBA101_2365	COG1113	amino acid transport
CHIBA101_2367	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHIBA101_2368	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHIBA101_2370	COG1940	carbohydrate kinase activity
CHIBA101_2372	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_2373	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_2374	COG1120	ATPase activity
CHIBA101_2376	COG0305	Participates in initiation and elongation during chromosome replication
CHIBA101_2378	COG0359	binds to the 23S rRNA
CHIBA101_2379	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHIBA101_2380	COG0629	single-stranded DNA binding
CHIBA101_2381	COG0360	Binds together with S18 to 16S ribosomal RNA
CHIBA101_2382	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHIBA101_2385	COG1953	Uracil, thiamine, allantoin
CHIBA101_2386	COG3960	tartronate-semialdehyde synthase activity
CHIBA101_2388	COG3958	Transketolase
CHIBA101_2389	COG3959	Transketolase, thiamine diphosphate binding domain
CHIBA101_2392	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHIBA101_2393	COG1953	Uracil, thiamine, allantoin
CHIBA101_2399	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHIBA101_2401	COG3311	Transcriptional regulator
CHIBA101_2406	COG0617	tRNA 3'-terminal CCA addition
CHIBA101_2411	COG3118	belongs to the thioredoxin family
CHIBA101_2413	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHIBA101_2414	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHIBA101_2416	COG1192	Involved in chromosome partitioning
CHIBA101_2417	COG0357	Ribosomal RNA small subunit methyltransferase G
CHIBA101_2419	COG0706	membrane insertase activity
CHIBA101_2420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHIBA101_2421	COG0594	ribonuclease P activity
CHIBA101_2422	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHIBA101_2423	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids