locus-tag	class	description
AM609_00015	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_00020	ENOG4105ESF	Peptidoglycan binding domain protein
AM609_00050	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AM609_00065	ENOG4105F3R	pts system mannose fructose sorbose family iid
AM609_00070	ENOG4105ETZ	PTS System
AM609_00080	ENOG4105YHU	PTS system
AM609_00095	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AM609_00145	ENOG4105BZ1	(ABC) transporter
AM609_00165	ENOG4105DKQ	ROK family
AM609_00180	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AM609_00200	ENOG4105CQ7	ATP-dependent helicase
AM609_00225	ENOG4108MGF	sugar kinase
AM609_00250	ENOG4105SYT	Methylenetetrahydrofolate reductase
AM609_00255	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AM609_00260	ENOG4106N3A	copper homeostasis protein cutc
AM609_00270	ENOG4105BZ1	(ABC) transporter
AM609_00275	ENOG4105BZ1	(ABC) transporter
AM609_00290	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
AM609_00335	ENOG4105EN6	Membrane
AM609_00345	ENOG4108XI2	Domain of unknown function (DUF1963)
AM609_00370	ENOG4108ZF3	Phosphatase
AM609_00395	ENOG4105C0D	helicase
AM609_00445	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AM609_00510	ENOG4105CFG	Acts as a chaperone (By similarity)
AM609_00695	ENOG4108UCS	ABC, transporter
AM609_00720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AM609_00725	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AM609_00730	ENOG4105DEF	Extracellular solute-binding protein, family 5
AM609_00765	ENOG4107U9K	TROVE domain-containing protein
AM609_00805	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AM609_00840	ENOG4105M6F	mutator MutT protein
AM609_00870	ENOG4105DHP	deoxycytidine triphosphate deaminase
AM609_00885	ENOG4108DBC	nitroreductase
AM609_00900	ENOG4105EMU	Dehydrogenase
AM609_00910	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AM609_00940	ENOG4107RCW	fructose-bisphosphate aldolase
AM609_00980	ENOG4105EBR	Carboxylesterase
AM609_00990	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AM609_01030	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AM609_01065	ENOG4105C12	Phosphoribosylglycinamide synthetase
AM609_01070	ENOG4105C8V	SAICAR synthetase
AM609_01080	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AM609_01095	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AM609_01140	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AM609_01165	ENOG4105VE1	Phosphatidylcholine synthase
AM609_01185	ENOG4105D82	Glutamate dehydrogenase
AM609_01195	ENOG4105E98	transcriptional regulator DeoR family
AM609_01200	ENOG4105DE4	1-phosphofructokinase
AM609_01220	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AM609_01255	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AM609_01260	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AM609_01265	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AM609_01300	ENOG4105BZ1	(ABC) transporter
AM609_01310	ENOG4105EHG	Permease protein
AM609_01320	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AM609_01330	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_01355	ENOG4105CRK	lysyL-tRNA synthetase
AM609_01385	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AM609_01405	ENOG4105DEI	Mannitol dehydrogenase
AM609_01410	ENOG41080R8	Conserved Protein
AM609_01415	ENOG4107QR9	Iron-sulfur cluster binding protein
AM609_01420	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AM609_01470	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AM609_01480	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AM609_01545	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AM609_01550	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AM609_01575	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
AM609_01580	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AM609_01610	ENOG4105E2R	ROK family
AM609_01620	ENOG4105EBR	Carboxylesterase
AM609_01660	ENOG4107WI4	Aldose-1-epimerase
AM609_01685	ENOG4105CNT	hydrolase family 2
AM609_01700	ENOG4105CZN	Potassium uptake protein
AM609_01710	ENOG4107R4N	Cell wall formation (By similarity)
AM609_01725	ENOG4105BZG	amino acid carrier protein
AM609_01760	ENOG410683Z	Preprotein translocase SecE subunit
AM609_01765	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AM609_01770	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AM609_01775	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AM609_01780	ENOG4108QVN	serine threonine protein kinase
AM609_01785	ENOG4107QKZ	Ompa motb domain protein
AM609_01795	ENOG4108VZM	50s ribosomal protein L10
AM609_01800	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AM609_01805	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AM609_01810	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AM609_01820	ENOG4105CFG	Acts as a chaperone (By similarity)
AM609_01915	ENOG4105GSW	
AM609_01920	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AM609_01925	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AM609_01930	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AM609_01935	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AM609_01955	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AM609_01960	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AM609_01970	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AM609_01975	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM609_01980	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AM609_01990	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AM609_01995	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AM609_02000	ENOG41082SA	50s ribosomal protein l29
AM609_02005	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AM609_02015	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AM609_02020	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AM609_02025	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM609_02030	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AM609_02040	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AM609_02050	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AM609_02055	ENOG410849U	50S ribosomal protein L30
AM609_02060	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AM609_02075	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AM609_02080	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AM609_02085	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AM609_02090	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AM609_02095	ENOG41067V7	50S ribosomal protein L36
AM609_02100	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM609_02105	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AM609_02110	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AM609_02115	ENOG4108ZT0	50S ribosomal protein l17
AM609_02130	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AM609_02135	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AM609_02140	ENOG4108UJD	30S ribosomal protein S9
AM609_02175	ENOG4105CS9	pantothenic acid kinase
AM609_02180	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AM609_02185	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AM609_02195	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AM609_02200	ENOG4108097	ATP-binding protein
AM609_02225	ENOG4105E33	succinate dehydrogenase
AM609_02230	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AM609_02235	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
AM609_02245	ENOG4108UB4	uncharacterized protein ygjQ
AM609_02250	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AM609_02255	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AM609_02260	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AM609_02275	ENOG4107QVP	Dehydrogenase
AM609_02280	ENOG410849S	phosphocarrier protein (HPr)
AM609_02285	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AM609_02295	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AM609_02305	ENOG4107QNK	)-transporter
AM609_02320	ENOG41073TP	transcriptional regulator
AM609_02325	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AM609_02345	ENOG4105CPC	Aldo Keto reductase
AM609_02370	ENOG4105CJ1	ABC, transporter
AM609_02375	ENOG4105BZU	Histidine kinase
AM609_02380	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_02395	ENOG4107R3N	Filamentation induced by cAMP protein fic
AM609_02410	ENOG4107RSM	transcriptional regulator
AM609_02435	ENOG4108JJB	ABC transporter
AM609_02475	ENOG4108Z8I	decarboxylase
AM609_02480	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AM609_02490	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AM609_02505	ENOG4105CNN	ABC, transporter
AM609_02515	ENOG4105ETE	Transcriptional regulator (LacI family
AM609_02520	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AM609_02570	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_02580	ENOG4105ESV	Glycosyl transferase, family 4
AM609_02590	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
AM609_02595	ENOG4105ZA1	atp synthase
AM609_02600	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AM609_02605	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AM609_02610	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AM609_02615	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AM609_02620	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AM609_02625	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AM609_02640	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
AM609_02660	ENOG4105CE4	GlcNAc 6-P deacetylase
AM609_02720	ENOG4108JJB	ABC transporter
AM609_02740	ENOG4105PWE	CRISPR-associated protein cas2
AM609_02745	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AM609_02755	ENOG4108VWQ	crispr-associated protein
AM609_02760	ENOG41060M0	Crispr-associated protein, cse4 family
AM609_02785	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AM609_02790	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AM609_02830	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_02835	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_02845	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AM609_02860	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AM609_02865	ENOG4105DIH	basic membrane
AM609_02870	ENOG4108JQ9	ABC transporter
AM609_02875	ENOG4105UIB	(ABC) transporter
AM609_02900	ENOG4107SIG	periplasmic solute binding protein
AM609_02905	ENOG4105DIK	(ABC) transporter
AM609_02910	ENOG4107RBD	ABC, transporter
AM609_02920	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AM609_02950	ENOG4108URH	decarboxylase
AM609_02960	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AM609_02970	ENOG4105EXC	Acyl-transferase
AM609_02980	ENOG4105CJW	magnesium transporter
AM609_02990	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
AM609_02995	ENOG4105PGM	cation diffusion facilitator family transporter
AM609_03005	ENOG4107T6F	Xaa-Pro aminopeptidase
AM609_03020	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AM609_03025	ENOG4105C1J	atp-dependent rna helicase
AM609_03050	ENOG4105C4R	Atp-dependent dna helicase
AM609_03100	ENOG4105C5Q	Transcriptional regulator
AM609_03105	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AM609_03135	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AM609_03145	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AM609_03150	ENOG4105CI1	PTS System
AM609_03165	ENOG4105CI1	PTS System
AM609_03170	ENOG4105FDP	GntR family transcriptional regulator
AM609_03195	ENOG4105BZW	Glycerate kinase
AM609_03200	ENOG4105C9K	Endothelin-converting enzyme 1
AM609_03225	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AM609_03230	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AM609_03235	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AM609_03265	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AM609_03270	ENOG4105DRS	transport system, permease
AM609_03280	ENOG4105ETE	Transcriptional regulator (LacI family
AM609_03290	ENOG4105D0C	transport protein
AM609_03305	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AM609_03340	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AM609_03345	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AM609_03350	ENOG4108KGH	TRANSCRIPTIONal
AM609_03390	ENOG4108RYC	glycosyltransferase
AM609_03450	ENOG4105IDI	abc transporter atp-binding protein
AM609_03465	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AM609_03480	ENOG4105CAK	Cell division ATP-binding protein ftsE
AM609_03485	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
AM609_03495	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AM609_03500	ENOG4108FN7	Aldo keto reductase
AM609_03510	ENOG4105C2W	permease
AM609_03515	ENOG4105FDP	GntR family transcriptional regulator
AM609_03520	ENOG4105DEF	Extracellular solute-binding protein, family 5
AM609_03535	ENOG4108JQ7	(ABC) transporter
AM609_03540	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AM609_03550	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AM609_03555	ENOG4108426	dNA-binding protein
AM609_03570	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AM609_03605	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AM609_03635	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AM609_03655	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
AM609_03670	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AM609_03670	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AM609_03685	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AM609_03690	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AM609_03695	ENOG4105YA8	Transcriptional regulator
AM609_03700	ENOG4105DTN	riboflavin biosynthesis protein ribF
AM609_03715	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_03730	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AM609_03735	ENOG4105C1V	Peptidase, M16
AM609_03740	ENOG4105E1F	short-chain dehydrogenase reductase
AM609_03750	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AM609_03775	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AM609_03780	ENOG4105CEY	Amp-dependent synthetase and ligase
AM609_03785	ENOG4105CEY	Amp-dependent synthetase and ligase
AM609_03805	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AM609_03815	ENOG4108V6E	Cell division protein mraZ
AM609_03820	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AM609_03835	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AM609_03845	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AM609_03850	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AM609_03860	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AM609_03865	ENOG4105DFU	Cell wall formation (By similarity)
AM609_03870	ENOG4105ME9	cell division protein FtsQ
AM609_03875	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AM609_03880	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AM609_03885	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AM609_03895	ENOG4107VQS	DivIVA family
AM609_03915	ENOG4105C0B	DNA polymerase III (alpha subunit)
AM609_03920	ENOG410848D	S4 domain protein YaaA
AM609_04000	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AM609_04020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AM609_04050	ENOG4105NBF	ammecr1 domain protein
AM609_04055	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AM609_04065	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AM609_04080	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AM609_04085	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AM609_04115	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AM609_04120	ENOG41084BS	50S ribosomal protein L35
AM609_04125	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AM609_04130	ENOG4108RWN	rrna methyltransferase
AM609_04150	ENOG4105CDA	abc transporter atp-binding protein
AM609_04160	ENOG4105DRP	amino acid AbC transporter
AM609_04165	ENOG4105DRP	amino acid AbC transporter
AM609_04170	ENOG4107XZQ	multidrug resistance protein
AM609_04235	ENOG410901E	Membrane
AM609_04240	ENOG4108Z66	YbaK ebsC protein
AM609_04275	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AM609_04280	ENOG4105C87	Aminotransferase class I and II
AM609_04290	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AM609_04315	ENOG4105CN5	Metallo-Beta-Lactamase
AM609_04325	ENOG4107QZI	cell division protein FtsK
AM609_04340	ENOG4105CEV	competence damage-inducible protein
AM609_04345	ENOG4105WBV	Transcriptional regulator
AM609_04355	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AM609_04360	ENOG4105KC9	Modulates RecA activity (By similarity)
AM609_04365	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AM609_04375	ENOG4105CEP	NADH dehydrogenase
AM609_04385	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AM609_04390	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM609_04400	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AM609_04435	ENOG4107SJW	iron permease, FTR1
AM609_04440	ENOG4108SDV	Periplasmic Protein
AM609_04455	ENOG4107R34	abc transporter permease protein
AM609_04480	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AM609_04525	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AM609_04535	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AM609_04540	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AM609_04555	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AM609_04580	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AM609_04600	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AM609_04605	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AM609_04610	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AM609_04620	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AM609_04650	ENOG4105CPF	Cell wall formation (By similarity)
AM609_04680	ENOG4105VB9	50S ribosomal protein l28
AM609_04685	ENOG4105DP4	dak2 domain fusion protein ylov
AM609_04710	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AM609_04730	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AM609_04755	ENOG4108JJ8	(ABC) transporter
AM609_04760	ENOG4108JJ9	ABC, transporter
AM609_04765	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AM609_04770	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AM609_04775	ENOG4105C03	ribonuclease
AM609_04780	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AM609_04785	ENOG4105K46	50S ribosomal protein l27
AM609_04790	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM609_04795	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AM609_04850	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AM609_04860	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AM609_04865	ENOG4105GR3	Histidine kinase
AM609_04870	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AM609_04885	ENOG4105BZ1	(ABC) transporter
AM609_04905	ENOG4105E98	transcriptional regulator DeoR family
AM609_04910	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AM609_04925	ENOG4107TB6	phosphoglycerate mutase
AM609_04955	ENOG4108IUK	alpha amylase, catalytic
AM609_04970	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AM609_05005	ENOG4107ZUX	Histidine triad (HIT) protein
AM609_05010	ENOG4105C8T	Leucyl-tRNA synthetase
AM609_05015	ENOG4105KWG	Pfam:DUF1696
AM609_05035	ENOG4105EPR	degv family
AM609_05055	ENOG4105DPH	UPF0371 protein
AM609_05060	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AM609_05085	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_05095	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_05120	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_05150	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AM609_05155	ENOG4105RGK	anthranilate synthase component ii
AM609_05160	ENOG4105CRQ	synthase (Component I)
AM609_05175	ENOG4107QRS	glycosyltransferase group 2 family protein
AM609_05185	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AM609_05195	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AM609_05230	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AM609_05235	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AM609_05240	ENOG4105DFA	alanine racemase domain protein
AM609_05270	ENOG4105CIG	ABC transporter
AM609_05285	ENOG41082SX	arsR family transcriptional regulator
AM609_05310	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AM609_05330	ENOG4105C26	Dehydrogenase
AM609_05335	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AM609_05350	ENOG4105VZ8	Transcriptional regulator
AM609_05360	ENOG4105CJ1	ABC, transporter
AM609_05370	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AM609_05375	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
AM609_05385	ENOG4105CC5	ABC transporter
AM609_05390	ENOG4105FDK	ABC transporter
AM609_05400	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AM609_05425	ENOG4105EAC	phosphoserine phosphatase
AM609_05430	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AM609_05435	ENOG4107QPH	glycogen) synthase
AM609_05445	ENOG4105DKW	ABC transporter
AM609_05475	ENOG4105CSR	polyphosphate kinase 2
AM609_05490	ENOG4105C5H	ABC transporter
AM609_05505	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AM609_05545	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AM609_05565	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AM609_05585	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AM609_05635	ENOG4107VEG	TrkA-N domain protein
AM609_05640	ENOG4105C0X	amino acid
AM609_05645	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AM609_05655	ENOG4107QM5	aconitate hydratase
AM609_05665	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_05710	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AM609_05715	ENOG4105EMU	Dehydrogenase
AM609_05720	ENOG4108V1U	phospholipid-binding protein
AM609_05730	ENOG4107104	thymidine kinase
AM609_05745	ENOG4105DSB	aldose 1-epimerase
AM609_05770	ENOG4105DGW	oligopeptidase A
AM609_05785	ENOG4105DHS	permease protein
AM609_05790	ENOG4105CM4	permease protein
AM609_05795	ENOG4108IPW	abc transporter atp-binding protein
AM609_05800	ENOG4105CPC	Aldo Keto reductase
AM609_05820	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AM609_05830	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
AM609_05835	ENOG4105E5F	proteasome
AM609_05840	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
AM609_05845	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
AM609_05865	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AM609_05890	ENOG4105KA0	thioesterase Superfamily protein
AM609_05900	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AM609_05910	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AM609_05915	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AM609_05935	ENOG4105C26	Dehydrogenase
AM609_06000	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AM609_06005	ENOG4105X1Q	TOBE domain protein
AM609_06020	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AM609_06025	ENOG4105CHW	UPF0052 protein
AM609_06030	ENOG4105CIE	May be required for sporulation (By similarity)
AM609_06035	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AM609_06040	ENOG4105BZA	Phosphoglycerate kinase
AM609_06045	ENOG4105CP7	Triose-phosphate isomerase
AM609_06065	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AM609_06070	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AM609_06095	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AM609_06110	ENOG4107QP8	phosphohexose isomerase
AM609_06160	ENOG4105D9P	serine threonine protein kinase
AM609_06190	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AM609_06220	ENOG4108IJ9	(ABC) transporter
AM609_06225	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AM609_06230	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
AM609_06245	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
AM609_06255	ENOG4105CNT	hydrolase family 2
AM609_06260	ENOG4106T4V	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
AM609_06430	ENOG4108QVN	serine threonine protein kinase
AM609_06505	ENOG4108UVJ	appr-1-p processing domain protein
AM609_06510	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AM609_06540	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AM609_06545	ENOG4108UW8	fha domain-containing protein
AM609_06585	ENOG4105C5Y	PTS System
AM609_06590	ENOG4105ETE	Transcriptional regulator (LacI family
AM609_06610	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
AM609_06630	ENOG4105C57	major facilitator superfamily
AM609_06665	ENOG4105CTQ	phosphohexokinase
AM609_06670	ENOG4105Q70	
AM609_06675	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AM609_06705	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AM609_06725	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
AM609_06730	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AM609_06740	ENOG4107XKF	NMT1 THI5 Like Domain Protein
AM609_06745	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
AM609_06750	ENOG4105CK7	Sodium proline symporter
AM609_06765	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AM609_06770	ENOG4105D8K	carboxyl transferase
AM609_06775	ENOG4108JIK	carboxylase
AM609_06825	ENOG4105DJV	ribulose-phosphate 3-epimerase
AM609_06835	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AM609_06850	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AM609_06860	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AM609_06865	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AM609_06870	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AM609_06875	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AM609_06885	ENOG4105CD3	dihydroorotase
AM609_06890	ENOG4105CXT	aspartate transcarbamylase
AM609_06895	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AM609_06905	ENOG4105ECR	NmrA family
AM609_06910	ENOG410803B	Involved in the transcription termination process (By similarity)
AM609_06915	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AM609_06930	ENOG4105D49	3-dehydroquinate synthase
AM609_06935	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AM609_06940	ENOG4105E2X	shikimate dehydrogenase
AM609_06950	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AM609_06955	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AM609_06960	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AM609_06965	ENOG4105HF0	Membrane
AM609_06995	ENOG4105CB5	ATP-dependent DNA helicase recG
AM609_07005	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AM609_07020	ENOG4105CPQ	Dehydrogenase
AM609_07025	ENOG4105IE8	Alpha-ketoglutarate permease
AM609_07040	ENOG4108JJ7	ABC transporter
AM609_07045	ENOG4105C9M	aspartyl-trna synthetase
AM609_07060	ENOG4107UWC	ABC, transporter
AM609_07070	ENOG4105D7T	ABC transporter
AM609_07095	ENOG4105CUT	histidyl-tRNA synthetase
AM609_07115	ENOG4105C99	atpase involved in dna repair
AM609_07125	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AM609_07130	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AM609_07135	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AM609_07140	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AM609_07150	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AM609_07155	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AM609_07160	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AM609_07165	ENOG4105CDY	transcriptional regulatory protein
AM609_07185	ENOG4105E2K	Glycosyl transferase (Group 1
AM609_07190	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
AM609_07195	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
AM609_07205	ENOG4105C22	threonyL-tRNA synthetase
AM609_07250	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AM609_07265	ENOG4105C6N	Formate acetyltransferase
AM609_07295	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AM609_07330	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AM609_07335	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AM609_07345	ENOG4105C5F	glutamine synthetase
AM609_07355	ENOG4105E5Q	amino acid AbC transporter
AM609_07380	ENOG4105GCF	PGAM
AM609_07390	ENOG4105C5F	glutamine synthetase
AM609_07395	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AM609_07400	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AM609_07470	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AM609_07475	ENOG4105CHM	Aminotransferase
AM609_07500	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AM609_07505	ENOG4108IJ0	Aspartate ammonia-lyase
AM609_07515	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AM609_07535	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AM609_07560	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AM609_07565	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AM609_07585	ENOG4107FKK	extracellular solute-binding protein family 1
AM609_07590	ENOG4105D56	permease protein
AM609_07595	ENOG4105EG2	ABC transporter, permease
AM609_07600	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AM609_07605	ENOG4105ETE	Transcriptional regulator (LacI family
AM609_07610	ENOG4105BZW	Glycerate kinase
AM609_07615	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AM609_07625	ENOG4105CPC	Aldo Keto reductase
AM609_07655	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AM609_07685	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AM609_07700	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AM609_07705	ENOG4105VG1	fes assembly suf system protein
AM609_07720	ENOG4105C3K	feS assembly ATPase SufC
AM609_07745	ENOG41060NJ	transcriptional regulator
AM609_07750	ENOG4105I1K	ABC transporter
AM609_07755	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AM609_07800	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AM609_07805	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AM609_07820	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AM609_07845	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AM609_07865	ENOG4108VX5	3-methyladenine DNA glycosylase
AM609_07870	ENOG4105CH7	arginosuccinase
AM609_07885	ENOG4105CDH	Citrulline--aspartate ligase
AM609_07890	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AM609_07900	ENOG4105CAS	nag kinase
AM609_07905	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AM609_07910	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AM609_07920	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AM609_07940	ENOG4105CIG	ABC transporter
AM609_07980	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AM609_07985	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AM609_07990	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AM609_07995	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AM609_08040	ENOG4105DZP	Membrane-associated zinc metalloprotease
AM609_08045	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AM609_08055	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AM609_08065	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AM609_08070	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AM609_08075	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AM609_08080	ENOG4105CE9	30S ribosomal protein S2
AM609_08090	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AM609_08100	ENOG4105C0P	Mg chelatase subunit ChlI
AM609_08105	ENOG41082RQ	UPF0102 protein
AM609_08115	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AM609_08120	ENOG4107QYR	Signal peptidase i
AM609_08130	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AM609_08135	ENOG4107QYR	Signal peptidase i
AM609_08140	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AM609_08145	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AM609_08150	ENOG41082KU	UPF0109 protein
AM609_08155	ENOG4105K5M	30s ribosomal protein S16
AM609_08170	ENOG4108M15	ABC transporter
AM609_08180	ENOG4105BZU	Histidine kinase
AM609_08185	ENOG4108S01	response regulator
AM609_08190	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AM609_08200	ENOG4108M15	ABC transporter
AM609_08205	ENOG4105KCT	ABC transporter
AM609_08210	ENOG4108ZGX	Histidine kinase
AM609_08220	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AM609_08245	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_08255	ENOG4105DA5	(ABC) transporter
AM609_08270	ENOG4108IUX	(ABC) transporter
AM609_08280	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AM609_08290	ENOG4108UTZ	Dihydroxyacetone kinase
AM609_08295	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AM609_08300	ENOG4105D3Q	Sugar transferase
AM609_08325	ENOG4105K64	Glycosyl transferase, family 2
AM609_08435	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AM609_08440	ENOG4107414	GntR family transcriptional regulator
AM609_08445	ENOG4105C5Y	PTS System
AM609_08450	ENOG4105CG3	alpha amylase, catalytic region
AM609_08480	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AM609_08485	ENOG41084HI	prevent-host-death family
AM609_08495	ENOG4107R3N	Filamentation induced by cAMP protein fic
AM609_08510	ENOG4105II7	pyrroline-5-carboxylate reductase
AM609_08515	ENOG4108JJB	ABC transporter
AM609_08530	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AM609_08545	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AM609_08550	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AM609_08555	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AM609_08560	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AM609_08565	ENOG4105E2Y	ABC, transporter
AM609_08620	ENOG4105EDR	glucose galactose transporter
AM609_08630	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
AM609_08735	ENOG41067C8	50S ribosomal protein L32
AM609_08740	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AM609_08750	ENOG4105D7W	serine acetyltransferase
AM609_08755	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AM609_08795	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AM609_08800	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AM609_08805	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
AM609_08815	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
AM609_08820	ENOG4108IJ8	ABC transporter
AM609_08845	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
AM609_08860	ENOG41065SU	Two-component system sensor kinase
AM609_08875	ENOG4105C9Q	fumarate hydratase class II
AM609_08880	ENOG4105MSB	protein, conserved in bacteria
AM609_08900	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_08920	ENOG4105DJZ	UPF0182 protein
AM609_08935	ENOG41063PX	domain protein
AM609_09000	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AM609_09010	ENOG4105CZV	ABC transporter
AM609_09015	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AM609_09040	ENOG4108KDT	Molybdate metabolism regulator
AM609_09060	ENOG4105DEG	Vwa containing coxe family protein
AM609_09070	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
AM609_09080	ENOG4105C10	Electron transfer flavoprotein
AM609_09085	ENOG4105BZJ	Electron transfer flavoprotein
AM609_09100	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AM609_09120	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AM609_09125	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
AM609_09130	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AM609_09175	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AM609_09205	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AM609_09215	ENOG4105CTQ	phosphohexokinase
AM609_09270	ENOG4105ETE	Transcriptional regulator (LacI family
AM609_09295	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AM609_09300	ENOG4105CG3	alpha amylase, catalytic region
AM609_09320	ENOG4105E2R	ROK family
AM609_09330	ENOG4105ETE	Transcriptional regulator (LacI family
AM609_09340	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AM609_09345	ENOG4105DRS	transport system, permease
AM609_09355	ENOG4108PSK	reductase
AM609_09420	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AM609_09425	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AM609_09430	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AM609_09450	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AM609_09455	ENOG4105D6E	homoserine dehydrogenase
AM609_09465	ENOG4108JJB	ABC transporter
AM609_09520	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AM609_09525	ENOG4105C75	arginyL-tRNA synthetase
AM609_09560	ENOG4105EBR	Carboxylesterase
AM609_09565	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AM609_09570	ENOG4105E4C	Lytic transglycosylase catalytic
AM609_09600	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AM609_09630	ENOG4108JGH	Tetr family transcriptional regulator
AM609_09635	ENOG4105CIG	ABC transporter
AM609_09645	ENOG4105WMN	AntiSigma factor
AM609_09650	ENOG4105EMN	RNA polymerase sigma factor
AM609_09660	ENOG4105E9K	Isocitrate dehydrogenase
AM609_09665	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AM609_09670	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AM609_09700	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AM609_09710	ENOG4108ZAF	Molybdopterin
AM609_09730	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AM609_09745	ENOG4108IUE	nitrate reductase beta subunit
AM609_09790	ENOG4105E2A	Dehydrogenase
AM609_09810	ENOG4107TK4	histidinol-phosphate phosphatase
AM609_09815	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AM609_09820	ENOG4105CDV	Ompa motb domain protein
AM609_09850	ENOG4107RH8	nuclease SbcCD subunit D
AM609_09855	ENOG4105EYH	Exonuclease
AM609_09895	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AM609_09905	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
AM609_09910	ENOG4108MKR	lipoprotein lpqb
AM609_09915	ENOG4105BZU	Histidine kinase
AM609_09920	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AM609_09935	ENOG4108WQ6	secreted protein
AM609_09940	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AM609_09980	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AM609_09990	ENOG4105EIP	mannose-6-phosphate isomerase
AM609_10025	ENOG4105EY8	ABC transporter
AM609_10075	ENOG4106MCE	EamA-like transporter family
AM609_10110	ENOG4108IJ1	Dehydrogenase
AM609_10140	ENOG4107T8Q	Glycosyl transferase (Group 1
AM609_10180	ENOG4108KGH	TRANSCRIPTIONal
AM609_10185	ENOG4108KGH	TRANSCRIPTIONal
AM609_10190	ENOG4105CMR	udp-glucose 4-epimerase
AM609_10195	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AM609_10225	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
AM609_10230	ENOG4105BZU	Histidine kinase
AM609_10235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AM609_10275	ENOG41065SU	Two-component system sensor kinase
AM609_10280	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AM609_10290	ENOG4107WR6	Maf-like protein
AM609_10300	ENOG4105WDJ	50S ribosomal protein L33
AM609_10340	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AM609_10350	ENOG4105D0M	Protease HtpX homolog
AM609_10355	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AM609_10440	ENOG4105DCF	alanine dehydrogenase
AM609_10460	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AM609_10470	ENOG4105D65	subunit l
AM609_10475	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AM609_10485	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AM609_10490	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AM609_10495	ENOG4108IEH	NADH dehydrogenase subunit g
AM609_10500	ENOG4107QIZ	NADH dehydrogenase
AM609_10510	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AM609_10520	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AM609_10545	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AM609_10550	ENOG4105C0H	protease
AM609_10555	ENOG4107TCW	O-succinylbenzoate synthase
AM609_10560	ENOG4105DBV	ornithine carbamoyltransferase
AM609_10580	ENOG4105CEU	Arginine dihydrolase
AM609_10590	ENOG4105RNG	membrane
AM609_10610	ENOG4105C79	DNA protecting protein DprA
AM609_10650	ENOG4108RH7	phosphoglycerate mutase
AM609_10655	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AM609_10690	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AM609_10695	ENOG41084HI	prevent-host-death family
AM609_10700	ENOG4105CS2	ec 3.2.1.21
AM609_10725	ENOG4108Z4U	Ferredoxin
AM609_10735	ENOG4105CI3	gtp-binding protein typa
AM609_10770	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AM609_10775	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AM609_10785	ENOG4105DEN	Luciferase family
AM609_10795	ENOG4105VKD	bioY protein
AM609_10825	ENOG4108NRW	Phospholipase, patatin family
AM609_10830	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AM609_10840	ENOG4105K5B	UPF0225 protein
AM609_10845	ENOG4105DFM	M18 family aminopeptidase
AM609_10910	ENOG4107YVI	ribose 5-phosphate isomerase
AM609_10915	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AM609_10920	ENOG4105KT7	mgtC SapB transporter
AM609_10975	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AM609_10985	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AM609_10995	ENOG4105C3G	gtp-binding protein
AM609_11015	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AM609_11020	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AM609_11025	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AM609_11030	ENOG4105D7K	pfkb domain protein
AM609_11035	ENOG4108IAB	Phoh family
AM609_11040	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AM609_11050	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AM609_11055	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AM609_11070	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AM609_11085	ENOG4105VUN	Transcriptional regulator
AM609_11095	ENOG4108YYH	Nadph-dependent fmn reductase
AM609_11100	ENOG4105C7B	Threonine dehydratase
AM609_11105	ENOG4105F6J	Alpha beta hydrolase fold
AM609_11120	ENOG4108IG5	Transcriptional regulator
AM609_11135	ENOG4105C01	Dihydroxy-acid dehydratase
AM609_11140	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AM609_11185	ENOG4105CJ1	ABC, transporter
AM609_11195	ENOG4105ENE	Histidine kinase
AM609_11200	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_11205	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AM609_11210	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AM609_11215	ENOG4105FF2	Type I DHQase
AM609_11235	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AM609_11255	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AM609_11260	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AM609_11270	ENOG41067SE	Tetr family transcriptional regulator
AM609_11275	ENOG4105C5H	ABC transporter
AM609_11280	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AM609_11285	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AM609_11300	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AM609_11345	ENOG41062ES	Transcriptional regulator
AM609_11370	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
AM609_11380	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AM609_11410	ENOG4105K4H	Nlp p60 protein
AM609_11425	ENOG4105C7N	Xanthine uracil vitamin C permease
AM609_11430	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AM609_11445	ENOG4105C26	Dehydrogenase
AM609_11455	ENOG4105EUJ	GTP cyclohydrolase i
AM609_11460	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AM609_11550	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AM609_11605	ENOG4105F0N	pyrophosphate phospho-hydrolase
AM609_11615	ENOG4108IQK	o-acetylhomoserine
AM609_11620	ENOG4105DWV	Homoserine O-trans-acetylase
AM609_11625	ENOG4105FF5	Membrane
AM609_11655	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AM609_11660	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AM609_11670	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AM609_11690	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AM609_11705	ENOG4105BZU	Histidine kinase
AM609_11845	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AM609_11880	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AM609_11890	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AM609_11895	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
AM609_11905	ENOG4107NHD	transcriptional regulator
AM609_11915	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AM609_11970	ENOG4105C1J	atp-dependent rna helicase
AM609_12040	ENOG4105DIK	(ABC) transporter
AM609_12060	ENOG4107RBB	ABC transporter, permease
AM609_12070	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AM609_12085	ENOG4105CFI	type iii restriction protein res subunit
AM609_12130	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AM609_12135	ENOG4105BZU	Histidine kinase
AM609_12160	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AM609_12175	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AM609_12235	ENOG4105C8N	cysteinyl-tRNA synthetase
AM609_12240	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AM609_12250	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AM609_12295	ENOG4105E98	transcriptional regulator DeoR family
AM609_12300	ENOG4105DUX	Transporter
AM609_12305	ENOG4105DM4	PTS System
AM609_12310	ENOG4108YRF	PTS System
AM609_12315	ENOG4105DM4	PTS System
AM609_12335	ENOG4108IG5	Transcriptional regulator
AM609_12345	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AM609_12355	ENOG4105VMP	Transcriptional regulator
AM609_12390	ENOG4105F44	Two component transcriptional regulator, winged helix family
AM609_12400	ENOG4105KNI	merR family transcriptional Regulator
AM609_12405	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AM609_12410	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM609_12415	ENOG4105CFG	Acts as a chaperone (By similarity)
AM609_12430	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_12505	ENOG4107QPK	)-transporter
AM609_12545	ENOG4105VT3	DNA binding domain protein, excisionase family
AM609_12565	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AM609_12600	ENOG4107QRT	dEAD DEAH box helicase
AM609_12605	ENOG41088T4	Helicase IV
AM609_12630	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AM609_12690	ENOG4108IND	Tetr family transcriptional regulator
AM609_12710	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AM609_12720	ENOG41062D9	Histidine kinase
AM609_12725	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AM609_12735	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AM609_12750	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AM609_12755	ENOG4105BZU	Histidine kinase
AM609_12760	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
AM609_12845	ENOG4105D74	hydrolase
AM609_12855	ENOG4105IJJ	transcriptional regulator, crp fnr family
AM609_12865	ENOG4108JQC	penicillin-binding protein 1A
AM609_12895	ENOG4107TE5	Lipid kinase
AM609_12980	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AM609_12985	ENOG4107JTW	chlorite dismutase
AM609_12990	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AM609_13000	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AM609_13015	ENOG4105D52	delta-aminolevulinic acid dehydratase
AM609_13025	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AM609_13030	ENOG4105DM4	PTS System
AM609_13045	ENOG4105CS2	ec 3.2.1.21
AM609_13100	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_13105	ENOG41080RH	Thioredoxin
AM609_13115	ENOG4105HX0	Transcriptional regulator
AM609_13145	ENOG4105CFH	Aspartokinase
AM609_13170	ENOG4105CJ1	ABC, transporter
AM609_13190	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AM609_13235	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
AM609_13245	ENOG4105WYW	fructose-bisphosphate aldolase
AM609_13250	ENOG4105ETE	Transcriptional regulator (LacI family
AM609_13255	ENOG4105CNT	hydrolase family 2
AM609_13260	ENOG4105CT4	transporter
AM609_13300	ENOG4105KME	endoribonuclease L-psp
AM609_13335	ENOG4105YXB	Toxic component of a toxin-antitoxin (TA) module. A
AM609_13360	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AM609_13390	ENOG4105CTZ	aminopeptidase c
AM609_13405	ENOG41082T9	Membrane
AM609_13410	ENOG4107QTF	adenylosuccinate lyase
AM609_13420	ENOG4105VPX	protein, conserved in bacteria
AM609_13460	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM609_13470	ENOG4106KNT	transcriptional regulator
AM609_13475	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AM609_13520	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AM609_13540	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AM609_13575	ENOG4105CG3	alpha amylase, catalytic region
AM609_13590	ENOG4105EJQ	L-serine dehydratase
AM609_13605	ENOG4105WMR	Protein CrcB homolog
AM609_13610	ENOG41083TI	Protein CrcB homolog
AM609_13615	ENOG4105C85	amino acid
AM609_13630	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AM609_13725	ENOG4105EC2	ftsk spoIIIe
AM609_13860	ENOG4105DSF	transport protein
AM609_13870	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_13915	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_13925	ENOG4107R3N	Filamentation induced by cAMP protein fic
AM609_13935	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_13950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_13960	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_13975	ENOG4105C57	major facilitator superfamily
AM609_14010	ENOG4105C8P	)-transporter
AM609_14025	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AM609_14040	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AM609_14050	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AM609_14080	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AM609_14100	ENOG4105TV9	FHA Domain-Containing protein
AM609_14105	ENOG4105HZM	Fha domain containing protein
AM609_14120	ENOG4105CJN	penicillin-binding protein
AM609_14125	ENOG4107TPY	serine threonine protein kinase
AM609_14130	ENOG4105D9P	serine threonine protein kinase
AM609_14140	ENOG4108U4N	(sortase) family
AM609_14145	ENOG4105ZJT	Cell division protein CrgA
AM609_14185	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AM609_14195	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AM609_14200	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AM609_14205	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AM609_14210	ENOG41084CH	50S ribosomal protein l34
AM609_14215	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AM609_14220	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AM609_14225	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AM609_14235	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AM609_14240	ENOG4107QJE	Chromosome Partitioning Protein
AM609_14255	ENOG4105CPF	Cell wall formation (By similarity)
AM609_14260	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AM609_14265	ENOG4105D98	threonine synthase
AM609_14270	ENOG4108UW5	maltose o-acetyltransferase
AM609_14275	ENOG4105K63	Thioredoxin
AM609_14280	ENOG4105C3M	thioredoxin reductase
AM609_14380	ENOG4108S01	response regulator
AM609_14395	ENOG4108JQ1	Dehydrogenase
AM609_14460	ENOG4107TXC	Transcriptional regulator
AM609_14465	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AM609_14475	ENOG4108JQC	penicillin-binding protein 1A
AM609_14480	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
AM609_14490	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AM609_14495	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AM609_14510	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_14515	ENOG4107QI1	Mate efflux family protein
AM609_14520	ENOG4105CDU	Replicative dna helicase
AM609_14535	ENOG4108IQI	permease
AM609_14540	ENOG4106V2I	dimethylaminohydrolase
AM609_14550	ENOG4105FDK	ABC transporter
AM609_14565	ENOG4105CB5	ATP-dependent DNA helicase recG
AM609_14570	ENOG4105DWF	phosphomethylpyrimidine kinase
AM609_14590	ENOG4107QW3	Sucrose phosphorylase
AM609_14605	ENOG4105IDI	abc transporter atp-binding protein
AM609_14615	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AM609_14620	ENOG4105ECY	inositol monophosphatase
AM609_14695	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AM609_14705	ENOG4105D01	(LipO)protein
AM609_14745	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AM609_14750	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_14765	ENOG4108UW5	maltose o-acetyltransferase
AM609_14790	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AM609_14840	ENOG4105C2W	permease
AM609_14900	ENOG4108UW5	maltose o-acetyltransferase
AM609_14905	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AM609_14910	ENOG4105C94	Transporter
AM609_14920	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AM609_14950	ENOG4105C5Q	Transcriptional regulator
AM609_14955	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AM609_14960	ENOG410667J	hydrolase
AM609_14965	ENOG4105EPJ	extracellular solute-binding protein family 1
AM609_14970	ENOG4107QKS	N-acylglucosamine 2-epimerase
AM609_15000	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AM609_15045	ENOG4105C87	Aminotransferase class I and II
AM609_15050	ENOG4105BZ1	(ABC) transporter
AM609_15055	ENOG4105BZ1	(ABC) transporter
AM609_15060	ENOG4108RVA	ribokinase
AM609_15095	ENOG4105K78	MarR family Transcriptional regulator
AM609_15100	ENOG4105D1H	recombination factor protein RarA
AM609_15110	ENOG4107XGZ	Hydrolase
AM609_15195	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_15200	ENOG4105BZU	Histidine kinase
AM609_15205	ENOG4105WH1	Two component transcriptional regulator luxr family
AM609_15225	ENOG4105DF6	Fe-S oxidoreductase
AM609_15240	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AM609_15245	ENOG4107QRG	dna polymerase iii
AM609_15265	ENOG4105HDK	L-asparaginase
AM609_15280	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AM609_15285	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AM609_15300	ENOG4108VJ1	Transcriptional regulator (CarD family
AM609_15305	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AM609_15320	ENOG4107R13	MMPL domain protein