locus-tag	class	description
C3V41_00010	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C3V41_00030	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C3V41_00075	ENOG4105EC2	ftsk spoIIIe
C3V41_00135	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_00140	ENOG4105BZU	Histidine kinase
C3V41_00180	ENOG4105ETE	Transcriptional regulator (LacI family
C3V41_00185	ENOG4107QNK	)-transporter
C3V41_00190	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C3V41_00225	ENOG4105CJ1	ABC, transporter
C3V41_00230	ENOG4105BZU	Histidine kinase
C3V41_00235	ENOG4108S01	response regulator
C3V41_00245	ENOG4105CPC	Aldo Keto reductase
C3V41_00265	ENOG4105CV8	reductase
C3V41_00270	ENOG41067QW	Transcriptional regulator
C3V41_00275	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3V41_00285	ENOG410756H	nucleotidyltransferase
C3V41_00360	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C3V41_00390	ENOG4105C08	Histidine kinase
C3V41_00395	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3V41_00410	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C3V41_00415	ENOG4105CI1	PTS System
C3V41_00425	ENOG4105C5Y	PTS System
C3V41_00430	ENOG4105CI1	PTS System
C3V41_00440	ENOG4105FDP	GntR family transcriptional regulator
C3V41_00470	ENOG4105CJ1	ABC, transporter
C3V41_00480	ENOG4105C9K	Endothelin-converting enzyme 1
C3V41_00505	ENOG4105D7W	serine acetyltransferase
C3V41_00515	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C3V41_00535	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C3V41_00555	ENOG4105E2Y	ABC, transporter
C3V41_00560	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C3V41_00565	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C3V41_00570	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C3V41_00575	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C3V41_00580	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
C3V41_00615	ENOG4108JJB	ABC transporter
C3V41_00625	ENOG4108JJB	ABC transporter
C3V41_00645	ENOG4105CG3	alpha amylase, catalytic region
C3V41_00650	ENOG4105C5Y	PTS System
C3V41_00655	ENOG4107414	GntR family transcriptional regulator
C3V41_00670	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C3V41_00675	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C3V41_00680	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C3V41_00690	ENOG4105CE9	30S ribosomal protein S2
C3V41_00695	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C3V41_00710	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C3V41_00715	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C3V41_00725	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C3V41_00735	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C3V41_00740	ENOG4105DZP	Membrane-associated zinc metalloprotease
C3V41_00770	ENOG4105FDP	GntR family transcriptional regulator
C3V41_00775	ENOG4105DEF	Extracellular solute-binding protein, family 5
C3V41_00790	ENOG4108JQ7	(ABC) transporter
C3V41_00795	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C3V41_00800	ENOG4105DKQ	ROK family
C3V41_00805	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
C3V41_00810	ENOG4108426	dNA-binding protein
C3V41_00825	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C3V41_00840	ENOG4107TTQ	Alpha beta hydrolase fold
C3V41_00850	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C3V41_00880	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C3V41_00885	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C3V41_00935	ENOG410901E	Membrane
C3V41_00940	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
C3V41_00945	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C3V41_00950	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C3V41_00955	ENOG4105E9K	Isocitrate dehydrogenase
C3V41_00965	ENOG4107U9K	TROVE domain-containing protein
C3V41_00975	ENOG4105EMN	RNA polymerase sigma factor
C3V41_01000	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C3V41_01030	ENOG4107QKV	phosphomannomutase
C3V41_01035	ENOG4108IPW	abc transporter atp-binding protein
C3V41_01040	ENOG4105CM4	permease protein
C3V41_01045	ENOG4105DHS	permease protein
C3V41_01060	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
C3V41_01065	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C3V41_01080	ENOG4105C75	arginyL-tRNA synthetase
C3V41_01085	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C3V41_01105	ENOG4105D6E	homoserine dehydrogenase
C3V41_01110	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C3V41_01130	ENOG4105VFB	Binds the 23S rRNA (By similarity)
C3V41_01135	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C3V41_01140	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C3V41_01145	ENOG4105VTW	prevent-host-death family
C3V41_01150	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
C3V41_01210	ENOG4105RNG	membrane
C3V41_01215	ENOG4105K6V	RNA polymerase
C3V41_01250	ENOG4105CG3	alpha amylase, catalytic region
C3V41_01260	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C3V41_01275	ENOG4105CTQ	phosphohexokinase
C3V41_01370	ENOG4105EC2	ftsk spoIIIe
C3V41_01375	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C3V41_01410	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C3V41_01415	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
C3V41_01420	ENOG4105BZ1	(ABC) transporter
C3V41_01425	ENOG4105BZ1	(ABC) transporter
C3V41_01430	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C3V41_01440	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
C3V41_01475	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C3V41_01530	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_01540	ENOG4105CJ1	ABC, transporter
C3V41_01570	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C3V41_01585	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
C3V41_01600	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C3V41_01600	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C3V41_01615	ENOG4105CEV	competence damage-inducible protein
C3V41_01620	ENOG4105WBV	Transcriptional regulator
C3V41_01630	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C3V41_01645	ENOG4105CKU	formyltetrahydrofolate synthetase
C3V41_01655	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_01670	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
C3V41_01675	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C3V41_01680	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C3V41_01715	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C3V41_01730	ENOG4107SJW	iron permease, FTR1
C3V41_01750	ENOG4107R34	abc transporter permease protein
C3V41_01775	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C3V41_01780	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C3V41_01785	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C3V41_01790	ENOG4105C57	major facilitator superfamily
C3V41_01800	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C3V41_01835	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C3V41_01845	ENOG4105CEY	Amp-dependent synthetase and ligase
C3V41_01850	ENOG4105CEY	Amp-dependent synthetase and ligase
C3V41_01870	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C3V41_01875	ENOG4105KT7	mgtC SapB transporter
C3V41_01885	ENOG4108V6E	Cell division protein mraZ
C3V41_01890	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C3V41_01900	ENOG4105CJN	penicillin-binding protein
C3V41_01905	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C3V41_01915	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C3V41_01920	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C3V41_01935	ENOG4105DFU	Cell wall formation (By similarity)
C3V41_01945	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C3V41_01950	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C3V41_01955	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C3V41_01965	ENOG4107VQS	DivIVA family
C3V41_01985	ENOG4105C0B	DNA polymerase III (alpha subunit)
C3V41_01990	ENOG410848D	S4 domain protein YaaA
C3V41_02035	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C3V41_02105	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C3V41_02125	ENOG4105EEQ	Na H antiporter
C3V41_02145	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C3V41_02160	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C3V41_02165	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C3V41_02180	ENOG4105BZ1	(ABC) transporter
C3V41_02190	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C3V41_02195	ENOG41084BS	50S ribosomal protein L35
C3V41_02200	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C3V41_02205	ENOG4105CDA	abc transporter atp-binding protein
C3V41_02210	ENOG4105CT1	(ABC) transporter
C3V41_02215	ENOG4105E5Q	amino acid AbC transporter
C3V41_02220	ENOG4105DRP	amino acid AbC transporter
C3V41_02225	ENOG4108RWN	rrna methyltransferase
C3V41_02245	ENOG4105CIG	ABC transporter
C3V41_02260	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C3V41_02280	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C3V41_02285	ENOG4105CAS	nag kinase
C3V41_02295	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C3V41_02300	ENOG4105CDH	Citrulline--aspartate ligase
C3V41_02320	ENOG4105CH7	arginosuccinase
C3V41_02325	ENOG4108VX5	3-methyladenine DNA glycosylase
C3V41_02340	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C3V41_02380	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C3V41_02385	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C3V41_02440	ENOG4105C3K	feS assembly ATPase SufC
C3V41_02450	ENOG4107YH3	SUF system FeS assembly protein, NifU family
C3V41_02455	ENOG4105VG1	fes assembly suf system protein
C3V41_02460	ENOG4105K78	MarR family Transcriptional regulator
C3V41_02480	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C3V41_02485	ENOG4105CPC	Aldo Keto reductase
C3V41_02510	ENOG4107R28	alpha amylase, catalytic region
C3V41_02515	ENOG4105EG2	ABC transporter, permease
C3V41_02520	ENOG4105D56	permease protein
C3V41_02525	ENOG4107FKK	extracellular solute-binding protein family 1
C3V41_02535	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C3V41_02540	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C3V41_02545	ENOG4105EGD	dinuclear metal center protein, YbgI family
C3V41_02575	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C3V41_02605	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C3V41_02610	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C3V41_02615	ENOG4105DFA	alanine racemase domain protein
C3V41_02630	ENOG4105CIG	ABC transporter
C3V41_02650	ENOG4105BZ1	(ABC) transporter
C3V41_02665	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C3V41_02675	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C3V41_02685	ENOG4107QNK	)-transporter
C3V41_02690	ENOG4105VZ8	Transcriptional regulator
C3V41_02700	ENOG4105CJ1	ABC, transporter
C3V41_02705	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C3V41_02710	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
C3V41_02715	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C3V41_02725	ENOG4105CC5	ABC transporter
C3V41_02730	ENOG4105E2Y	ABC, transporter
C3V41_02740	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C3V41_02750	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C3V41_02765	ENOG4105EAC	phosphoserine phosphatase
C3V41_02770	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C3V41_02775	ENOG4107QPH	glycogen) synthase
C3V41_02785	ENOG4105DKW	ABC transporter
C3V41_02820	ENOG4105C5H	ABC transporter
C3V41_02870	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3V41_02875	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C3V41_02890	ENOG4107QP8	phosphohexose isomerase
C3V41_02965	ENOG410667J	hydrolase
C3V41_02985	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
C3V41_03000	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C3V41_03025	ENOG4105CFG	Acts as a chaperone (By similarity)
C3V41_03045	ENOG4105C5Y	PTS System
C3V41_03050	ENOG4105ETE	Transcriptional regulator (LacI family
C3V41_03060	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C3V41_03080	ENOG4105CTQ	phosphohexokinase
C3V41_03085	ENOG4105Q70	
C3V41_03105	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C3V41_03110	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C3V41_03130	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
C3V41_03135	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C3V41_03145	ENOG4107XKF	NMT1 THI5 Like Domain Protein
C3V41_03150	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
C3V41_03155	ENOG4108V1U	phospholipid-binding protein
C3V41_03165	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C3V41_03215	ENOG4107QM5	aconitate hydratase
C3V41_03220	ENOG4105DZR	Type I site-specific deoxyribonuclease
C3V41_03225	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C3V41_03230	ENOG4105C0X	amino acid
C3V41_03235	ENOG4107VEG	TrkA-N domain protein
C3V41_03285	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3V41_03295	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3V41_03325	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C3V41_03330	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C3V41_03350	ENOG4105CP7	Triose-phosphate isomerase
C3V41_03355	ENOG4105BZA	Phosphoglycerate kinase
C3V41_03360	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C3V41_03365	ENOG4105CIE	May be required for sporulation (By similarity)
C3V41_03375	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C3V41_03390	ENOG4105C5Y	PTS System
C3V41_03400	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C3V41_03405	ENOG4108X4Q	Hydrolase
C3V41_03430	ENOG4108MWI	inositol mono-phosphatase
C3V41_03470	ENOG4105BZW	Glycerate kinase
C3V41_03475	ENOG4105CK7	Sodium proline symporter
C3V41_03480	ENOG4105IBS	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C3V41_03485	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C3V41_03490	ENOG4105D8K	carboxyl transferase
C3V41_03495	ENOG4108JIK	carboxylase
C3V41_03505	ENOG4105DJV	ribulose-phosphate 3-epimerase
C3V41_03515	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C3V41_03525	ENOG4105ESP	cell wall surface anchor family protein
C3V41_03535	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C3V41_03545	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C3V41_03550	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C3V41_03555	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C3V41_03560	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C3V41_03565	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C3V41_03570	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C3V41_03575	ENOG4105CD3	dihydroorotase
C3V41_03580	ENOG4105CXT	aspartate transcarbamylase
C3V41_03585	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C3V41_03595	ENOG4105ECR	NmrA family
C3V41_03600	ENOG410803B	Involved in the transcription termination process (By similarity)
C3V41_03605	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C3V41_03620	ENOG4105D49	3-dehydroquinate synthase
C3V41_03625	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C3V41_03630	ENOG4105E2X	shikimate dehydrogenase
C3V41_03640	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C3V41_03645	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C3V41_03650	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C3V41_03660	ENOG4107R13	MMPL domain protein
C3V41_03665	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C3V41_03680	ENOG41082SX	arsR family transcriptional regulator
C3V41_03690	ENOG4105C9M	aspartyl-trna synthetase
C3V41_03720	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C3V41_03725	ENOG4105CUT	histidyl-tRNA synthetase
C3V41_03730	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C3V41_03745	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C3V41_03765	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C3V41_03775	ENOG4105KA0	thioesterase Superfamily protein
C3V41_03800	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C3V41_03815	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C3V41_03825	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
C3V41_03835	ENOG4105E5F	proteasome
C3V41_03840	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
C3V41_03865	ENOG4105CV8	reductase
C3V41_03885	ENOG4105DGW	oligopeptidase A
C3V41_03890	ENOG4105C57	major facilitator superfamily
C3V41_03900	ENOG4105DSF	transport protein
C3V41_03910	ENOG4105DSB	aldose 1-epimerase
C3V41_03915	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C3V41_03925	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C3V41_03980	ENOG4105C6N	Formate acetyltransferase
C3V41_03995	ENOG4105CMQ	Chloride channel
C3V41_04025	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C3V41_04030	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C3V41_04055	ENOG4105C5F	glutamine synthetase
C3V41_04065	ENOG4105E5Q	amino acid AbC transporter
C3V41_04070	ENOG4105CDA	abc transporter atp-binding protein
C3V41_04080	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C3V41_04085	ENOG4105C5F	glutamine synthetase
C3V41_04110	ENOG4105CIG	ABC transporter
C3V41_04115	ENOG4105C99	atpase involved in dna repair
C3V41_04125	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C3V41_04130	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C3V41_04135	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C3V41_04140	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C3V41_04150	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C3V41_04155	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C3V41_04160	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C3V41_04165	ENOG4105CDY	transcriptional regulatory protein
C3V41_04170	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C3V41_04175	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C3V41_04180	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C3V41_04200	ENOG4105E2K	Glycosyl transferase (Group 1
C3V41_04205	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
C3V41_04210	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
C3V41_04220	ENOG4105C22	threonyL-tRNA synthetase
C3V41_04225	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C3V41_04250	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C3V41_04255	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C3V41_04265	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C3V41_04275	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C3V41_04310	ENOG4108JJB	ABC transporter
C3V41_04315	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C3V41_04320	ENOG4105DPH	UPF0371 protein
C3V41_04335	ENOG4105BZM	domain protein
C3V41_04340	ENOG4105EPR	degv family
C3V41_04345	ENOG4105C8T	Leucyl-tRNA synthetase
C3V41_04350	ENOG4107ZUX	Histidine triad (HIT) protein
C3V41_04380	ENOG4105C8J	)-transporter
C3V41_04385	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
C3V41_04395	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C3V41_04435	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C3V41_04440	ENOG4108IJ0	Aspartate ammonia-lyase
C3V41_04450	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C3V41_04470	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
C3V41_04495	ENOG4107TB6	phosphoglycerate mutase
C3V41_04500	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C3V41_04510	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C3V41_04515	ENOG4105E98	transcriptional regulator DeoR family
C3V41_04530	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C3V41_04535	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C3V41_04540	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C3V41_04545	ENOG4105K46	50S ribosomal protein l27
C3V41_04550	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C3V41_04555	ENOG4105C03	ribonuclease
C3V41_04560	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C3V41_04565	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C3V41_04570	ENOG4105C4X	radical SAM domain protein
C3V41_04590	ENOG4108JJ9	ABC, transporter
C3V41_04595	ENOG4108JJ8	(ABC) transporter
C3V41_04610	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C3V41_04615	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C3V41_04630	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C3V41_04645	ENOG4105ETE	Transcriptional regulator (LacI family
C3V41_04650	ENOG4107QNK	)-transporter
C3V41_04660	ENOG4105DP4	dak2 domain fusion protein ylov
C3V41_04665	ENOG4105VB9	50S ribosomal protein l28
C3V41_04695	ENOG4105CPF	Cell wall formation (By similarity)
C3V41_04705	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C3V41_04715	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C3V41_04730	ENOG4107EF8	Glycosyl transferase (Group 1
C3V41_04735	ENOG4105BZ1	(ABC) transporter
C3V41_04750	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C3V41_04755	ENOG4105BZU	Histidine kinase
C3V41_04760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3V41_04770	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C3V41_04810	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C3V41_04820	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C3V41_04840	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C3V41_04850	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C3V41_04855	ENOG4105C1V	Peptidase, M16
C3V41_04860	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C3V41_04880	ENOG4107Y80	Major Facilitator superfamily
C3V41_04885	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C3V41_04890	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C3V41_04900	ENOG4107QZI	cell division protein FtsK
C3V41_04905	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C3V41_04910	ENOG4105CRK	lysyL-tRNA synthetase
C3V41_04915	ENOG4105CN5	Metallo-Beta-Lactamase
C3V41_04945	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C3V41_04955	ENOG4105C87	Aminotransferase class I and II
C3V41_04960	ENOG4105ERH	Fumarylacetoacetate hydrolase
C3V41_04980	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C3V41_04995	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C3V41_05000	ENOG4105DR5	peptidase
C3V41_05010	ENOG4105CAK	Cell division ATP-binding protein ftsE
C3V41_05035	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C3V41_05040	ENOG4108UGD	Serine Threonine protein kinase
C3V41_05045	ENOG4108UGD	Serine Threonine protein kinase
C3V41_05050	ENOG4105IDI	abc transporter atp-binding protein
C3V41_05065	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C3V41_05070	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C3V41_05085	ENOG4105D0C	transport protein
C3V41_05100	ENOG4105CGK	Exodeoxyribonuclease III
C3V41_05130	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C3V41_05150	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C3V41_05155	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C3V41_05160	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C3V41_05175	ENOG4108IUE	nitrate reductase beta subunit
C3V41_05215	ENOG4108JJB	ABC transporter
C3V41_05230	ENOG4105D06	uba thif-type nad fad binding protein
C3V41_05240	ENOG4105TVJ	transport system, permease
C3V41_05240	ENOG4105TVJ	transport system, permease
C3V41_05255	ENOG4105E0A	ABC, transporter
C3V41_05265	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
C3V41_05275	ENOG4105E2A	Dehydrogenase
C3V41_05280	ENOG4107TK4	histidinol-phosphate phosphatase
C3V41_05285	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C3V41_05290	ENOG4107RH8	nuclease SbcCD subunit D
C3V41_05295	ENOG4105EYH	Exonuclease
C3V41_05305	ENOG4106MCE	EamA-like transporter family
C3V41_05350	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C3V41_05355	ENOG4105MJ2	Competence protein
C3V41_05360	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
C3V41_05365	ENOG4105G3P	Lipoprotein lpqB
C3V41_05375	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3V41_05390	ENOG4108WQ6	secreted protein
C3V41_05395	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C3V41_05415	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C3V41_05440	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C3V41_05455	ENOG4105EIP	mannose-6-phosphate isomerase
C3V41_05465	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C3V41_05470	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C3V41_05505	ENOG4105W0E	50S ribosomal protein L33
C3V41_05510	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C3V41_05515	ENOG4105NRA	50s ribosomal protein l31 type b
C3V41_05520	ENOG4108638	50S ribosomal protein L36
C3V41_05525	ENOG4105CE4	GlcNAc 6-P deacetylase
C3V41_05535	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
C3V41_05545	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C3V41_05550	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C3V41_05555	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C3V41_05560	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C3V41_05565	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C3V41_05570	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C3V41_05580	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
C3V41_05605	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_05625	ENOG4108Z0Z	intracellular protease Pfpi family
C3V41_05645	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
C3V41_05655	ENOG4105C1J	atp-dependent rna helicase
C3V41_05660	ENOG41081FY	multiple antibiotic resistance (MarC)-related
C3V41_05670	ENOG4105CK5	oxidoreductase
C3V41_05700	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
C3V41_05705	ENOG4105RD5	
C3V41_05715	ENOG4105PGM	cation diffusion facilitator family transporter
C3V41_05720	ENOG41080HT	Transcriptional regulator, arsr family
C3V41_05730	ENOG4105CJW	magnesium transporter
C3V41_05740	ENOG4105EXC	Acyl-transferase
C3V41_05750	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C3V41_05755	ENOG4107ZBN	O-methyltransferase
C3V41_05760	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C3V41_05770	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
C3V41_05775	ENOG4105DRS	transport system, permease
C3V41_05785	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C3V41_05800	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C3V41_05810	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
C3V41_05825	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
C3V41_05830	ENOG4108IJ8	ABC transporter
C3V41_05850	ENOG4105C9Q	fumarate hydratase class II
C3V41_05855	ENOG4105MSB	protein, conserved in bacteria
C3V41_05875	ENOG4108KD5	ADP-ribosylation crystallin J1
C3V41_05900	ENOG4105CNU	cell division protein FtsK
C3V41_05925	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C3V41_05945	ENOG4105E98	transcriptional regulator DeoR family
C3V41_05950	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C3V41_05965	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_05995	ENOG4105KPE	licD family
C3V41_06015	ENOG4105CKK	Glycosyl transferase, family 2
C3V41_06030	ENOG4105EY8	ABC transporter
C3V41_06045	ENOG410602S	Transferase
C3V41_06055	ENOG4105EXC	Acyl-transferase
C3V41_06115	ENOG4108RCF	TRANSCRIPTIONal
C3V41_06120	ENOG4108KGH	TRANSCRIPTIONal
C3V41_06125	ENOG4105CMR	udp-glucose 4-epimerase
C3V41_06155	ENOG4105BZU	Histidine kinase
C3V41_06160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3V41_06175	ENOG4107WR6	Maf-like protein
C3V41_06190	ENOG4105WDJ	50S ribosomal protein L33
C3V41_06210	ENOG4108VPT	UPF0234 protein
C3V41_06215	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C3V41_06220	ENOG4105D0M	Protease HtpX homolog
C3V41_06225	ENOG4105DCF	alanine dehydrogenase
C3V41_06235	ENOG4107WI4	Aldose-1-epimerase
C3V41_06265	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C3V41_06275	ENOG4105C0P	Mg chelatase subunit ChlI
C3V41_06280	ENOG41080R2	UPF0102 protein
C3V41_06290	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C3V41_06295	ENOG4107QYR	Signal peptidase i
C3V41_06315	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C3V41_06320	ENOG41082KU	UPF0109 protein
C3V41_06325	ENOG4105K5M	30s ribosomal protein S16
C3V41_06335	ENOG4105CZV	ABC transporter
C3V41_06360	ENOG4105BZU	Histidine kinase
C3V41_06380	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C3V41_06385	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
C3V41_06395	ENOG4105CEN	a g-specific adenine glycosylase
C3V41_06405	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_06415	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C3V41_06420	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C3V41_06425	ENOG410849S	phosphocarrier protein (HPr)
C3V41_06435	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C3V41_06440	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C3V41_06445	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C3V41_06455	ENOG4107GZ4	SanA protein
C3V41_06465	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
C3V41_06475	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C3V41_06480	ENOG4105E33	succinate dehydrogenase
C3V41_06510	ENOG4108097	ATP-binding protein
C3V41_06515	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C3V41_06520	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C3V41_06525	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C3V41_06530	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C3V41_06535	ENOG4105CS9	pantothenic acid kinase
C3V41_06570	ENOG4108UJD	30S ribosomal protein S9
C3V41_06575	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C3V41_06580	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C3V41_06590	ENOG4105CEP	NADH dehydrogenase
C3V41_06600	ENOG4108ZT0	50S ribosomal protein l17
C3V41_06605	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3V41_06610	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C3V41_06615	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C3V41_06620	ENOG41067V7	50S ribosomal protein L36
C3V41_06625	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C3V41_06645	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C3V41_06650	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C3V41_06655	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C3V41_06660	ENOG410849U	50S ribosomal protein L30
C3V41_06665	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C3V41_06670	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C3V41_06675	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C3V41_06685	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C3V41_06690	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C3V41_06695	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C3V41_06700	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C3V41_06705	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C3V41_06710	ENOG41082SA	50s ribosomal protein l29
C3V41_06715	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C3V41_06720	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C3V41_06725	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C3V41_06730	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C3V41_06735	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C3V41_06740	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C3V41_06745	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C3V41_06750	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C3V41_06755	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C3V41_06775	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C3V41_06780	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C3V41_06785	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C3V41_06790	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C3V41_06850	ENOG4105EC2	ftsk spoIIIe
C3V41_06890	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C3V41_07000	ENOG4108M24	von Willebrand factor, type A
C3V41_07025	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_07050	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C3V41_07090	ENOG4105EC2	ftsk spoIIIe
C3V41_07095	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3V41_07100	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3V41_07105	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C3V41_07110	ENOG4108VZM	50s ribosomal protein L10
C3V41_07120	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C3V41_07125	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C3V41_07130	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C3V41_07155	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C3V41_07160	ENOG4105E4F	Isochorismate synthase
C3V41_07170	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C3V41_07175	ENOG4107TCW	O-succinylbenzoate synthase
C3V41_07180	ENOG4105DBV	ornithine carbamoyltransferase
C3V41_07185	ENOG4105CEU	Arginine dihydrolase
C3V41_07190	ENOG4107SIQ	Naphthoate synthase
C3V41_07195	ENOG4105R3P	Inner membrane protein yagU
C3V41_07220	ENOG4108RH7	phosphoglycerate mutase
C3V41_07225	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
C3V41_07240	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
C3V41_07245	ENOG41084HI	prevent-host-death family
C3V41_07255	ENOG4108Z4U	Ferredoxin
C3V41_07265	ENOG4105CI3	gtp-binding protein typa
C3V41_07300	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C3V41_07305	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C3V41_07315	ENOG4105DEN	Luciferase family
C3V41_07340	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3V41_07345	ENOG4105DFM	M18 family aminopeptidase
C3V41_07405	ENOG4105CUZ	uba thif-type nad fad binding protein
C3V41_07425	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C3V41_07545	ENOG4105DF6	Fe-S oxidoreductase
C3V41_07585	ENOG4105CC5	ABC transporter
C3V41_07590	ENOG4105DIK	(ABC) transporter
C3V41_07605	ENOG4105DSE	periplasmic solute binding protein
C3V41_07630	ENOG4105C5Y	PTS System
C3V41_07635	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C3V41_07660	ENOG4105KNI	merR family transcriptional Regulator
C3V41_07665	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C3V41_07670	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C3V41_07675	ENOG4105CFG	Acts as a chaperone (By similarity)
C3V41_07685	ENOG4105CJ1	ABC, transporter
C3V41_07695	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_07810	ENOG4108UMN	azlc family
C3V41_07905	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C3V41_07910	ENOG4107TXC	Transcriptional regulator
C3V41_07920	ENOG4105CJ1	ABC, transporter
C3V41_07975	ENOG4105CFH	Aspartokinase
C3V41_07990	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
C3V41_08010	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
C3V41_08025	ENOG4105CC5	ABC transporter
C3V41_08030	ENOG4107RPQ	ABC transporter
C3V41_08035	ENOG4105DIK	(ABC) transporter
C3V41_08040	ENOG4107SIG	periplasmic solute binding protein
C3V41_08045	ENOG41080RH	Thioredoxin
C3V41_08065	ENOG4108X07	Tetr family transcriptional regulator
C3V41_08070	ENOG4105CIG	ABC transporter
C3V41_08110	ENOG4105C2W	permease
C3V41_08120	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C3V41_08125	ENOG4105C8N	cysteinyl-tRNA synthetase
C3V41_08130	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C3V41_08160	ENOG41067SE	Tetr family transcriptional regulator
C3V41_08185	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C3V41_08190	ENOG4105C5H	ABC transporter
C3V41_08195	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C3V41_08200	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C3V41_08215	ENOG4105F8V	Hydrolase, tatD family
C3V41_08220	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C3V41_08230	ENOG4108RWI	nicotinamidase
C3V41_08255	ENOG4105HDK	L-asparaginase
C3V41_08265	ENOG4107QRG	dna polymerase iii
C3V41_08295	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C3V41_08300	ENOG4108VJ1	Transcriptional regulator (CarD family
C3V41_08305	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3V41_08310	ENOG4105BZU	Histidine kinase
C3V41_08390	ENOG4107TPY	serine threonine protein kinase
C3V41_08415	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C3V41_08425	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C3V41_08515	ENOG4105C87	Aminotransferase class I and II
C3V41_08520	ENOG4105C28	cystathionine
C3V41_08550	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C3V41_08555	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C3V41_08565	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
C3V41_08580	ENOG4108DWA	Nad synthetase
C3V41_08585	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
C3V41_08595	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C3V41_08610	ENOG4107QKS	N-acylglucosamine 2-epimerase
C3V41_08615	ENOG4105EPJ	extracellular solute-binding protein family 1
C3V41_08625	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C3V41_08630	ENOG4105C5Q	Transcriptional regulator
C3V41_08640	ENOG4105DTT	CRISPR-associated helicase, cas3
C3V41_08685	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C3V41_08700	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C3V41_08705	ENOG4106KNT	transcriptional regulator
C3V41_08710	ENOG4106NDP	Transcriptional regulator
C3V41_08715	ENOG4105CNT	hydrolase family 2
C3V41_08720	ENOG4105CT4	transporter
C3V41_08740	ENOG4105C09	Bile acid
C3V41_08750	ENOG4105VT3	DNA binding domain protein, excisionase family
C3V41_08790	ENOG4105CUX	Signal transduction histidine kinase
C3V41_08795	ENOG4105C8P	)-transporter
C3V41_08820	ENOG4105J76	Periplasmic binding protein
C3V41_08825	ENOG4105DQ5	transport system permease protein
C3V41_08830	ENOG4108IHU	transport system permease protein
C3V41_08835	ENOG4105E0A	ABC, transporter
C3V41_08845	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C3V41_08855	ENOG4105ETX	regulatoR
C3V41_08860	ENOG4105BZU	Histidine kinase
C3V41_08865	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
C3V41_08875	ENOG4105VDH	Dihydroxyacetone kinase
C3V41_08880	ENOG4108UTZ	Dihydroxyacetone kinase
C3V41_08900	ENOG4105U5Y	Transcriptional regulator
C3V41_08955	ENOG4105EC2	ftsk spoIIIe
C3V41_08970	ENOG4105CB5	ATP-dependent DNA helicase recG
C3V41_08975	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C3V41_08980	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
C3V41_08985	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
C3V41_08990	ENOG4108Z3G	3H domain protein
C3V41_09005	ENOG4105KME	endoribonuclease L-psp
C3V41_09030	ENOG4105CJ1	ABC, transporter
C3V41_09040	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_09105	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C3V41_09125	ENOG4105CTZ	aminopeptidase c
C3V41_09175	ENOG41082T9	Membrane
C3V41_09185	ENOG4105VPX	protein, conserved in bacteria
C3V41_09210	ENOG4105ETE	Transcriptional regulator (LacI family
C3V41_09225	ENOG4105EG2	ABC transporter, permease
C3V41_09250	ENOG4108JQ1	Dehydrogenase
C3V41_09255	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C3V41_09270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C3V41_09275	ENOG41062IR	nudix hydrolase
C3V41_09285	ENOG4105CJR	Integral membrane protein (MviN
C3V41_09290	ENOG4105C3M	thioredoxin reductase
C3V41_09305	ENOG4105K63	Thioredoxin
C3V41_09315	ENOG4105D98	threonine synthase
C3V41_09325	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
C3V41_09330	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C3V41_09335	ENOG4105CPF	Cell wall formation (By similarity)
C3V41_09345	ENOG4107QJE	Chromosome Partitioning Protein
C3V41_09350	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C3V41_09360	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C3V41_09365	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C3V41_09375	ENOG41084CH	50S ribosomal protein l34
C3V41_09380	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C3V41_09385	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C3V41_09390	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C3V41_09405	ENOG4108IUW	ABC transporter
C3V41_09420	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C3V41_09425	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3V41_09430	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3V41_09505	ENOG4105EJQ	L-serine dehydratase
C3V41_09510	ENOG4105DWF	phosphomethylpyrimidine kinase
C3V41_09520	ENOG4105TV9	FHA Domain-Containing protein
C3V41_09525	ENOG4105HZM	Fha domain containing protein
C3V41_09540	ENOG4105CJN	penicillin-binding protein
C3V41_09555	ENOG4108BGT	CrcB-like protein
C3V41_09560	ENOG4107JBM	CrcB-like protein
C3V41_09570	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C3V41_09575	ENOG4105DKQ	ROK family
C3V41_09590	ENOG4105BZU	Histidine kinase
C3V41_09630	ENOG4108U4N	(sortase) family
C3V41_09635	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C3V41_09640	ENOG4105CPQ	Dehydrogenase
C3V41_09660	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
C3V41_09680	ENOG4105BZ4	penicillin-binding protein
C3V41_09685	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
C3V41_09695	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C3V41_09700	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C3V41_09720	ENOG4105UQX	Mate efflux family protein
C3V41_09725	ENOG4105CDU	Replicative dna helicase
C3V41_09795	ENOG4105YXB	Toxic component of a toxin-antitoxin (TA) module. A
C3V41_09800	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C3V41_09830	ENOG4105KJF	protein tyrosine phosphatase
C3V41_09845	ENOG4108Z6B	deaminase
C3V41_09855	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_09880	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C3V41_09885	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C3V41_09890	ENOG4105CQ7	ATP-dependent helicase
C3V41_09985	ENOG4105ST3	Transcriptional regulator
C3V41_10025	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
C3V41_10035	ENOG4107WGA	YidE YbjL
C3V41_10040	ENOG4105EMN	RNA polymerase sigma factor
C3V41_10060	ENOG4105DA5	(ABC) transporter
C3V41_10075	ENOG4105F9E	Shikimate 5-dehydrogenase
C3V41_10095	ENOG4105D3Q	Sugar transferase
C3V41_10120	ENOG4105D2T	synthase
C3V41_10125	ENOG4105F0R	Cytidylyltransferase
C3V41_10155	ENOG4105BZ1	(ABC) transporter
C3V41_10180	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C3V41_10240	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C3V41_10250	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
C3V41_10270	ENOG4105BZU	Histidine kinase
C3V41_10275	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3V41_10290	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C3V41_10305	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C3V41_10320	ENOG4105BZU	Histidine kinase
C3V41_10325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3V41_10335	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C3V41_10370	ENOG4105CFI	type iii restriction protein res subunit
C3V41_10385	ENOG4105C7N	Xanthine uracil vitamin C permease
C3V41_10415	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C3V41_10420	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C3V41_10480	ENOG4107YJ4	chain length determinant protein
C3V41_10485	ENOG4108RCF	TRANSCRIPTIONal
C3V41_10495	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C3V41_10500	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C3V41_10505	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_10540	ENOG4105C01	Dihydroxy-acid dehydratase
C3V41_10550	ENOG4105C7B	Threonine dehydratase
C3V41_10555	ENOG4108YYH	Nadph-dependent fmn reductase
C3V41_10575	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C3V41_10580	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C3V41_10595	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C3V41_10600	ENOG4108IAB	Phoh family
C3V41_10605	ENOG4105D7K	pfkb domain protein
C3V41_10610	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C3V41_10615	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C3V41_10620	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C3V41_10625	ENOG4108QVN	serine threonine protein kinase
C3V41_10830	ENOG4105C3G	gtp-binding protein
C3V41_10870	ENOG4108UCS	ABC, transporter
C3V41_10885	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C3V41_10895	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C3V41_10920	ENOG4105CQ7	ATP-dependent helicase
C3V41_10920	ENOG4105CQ7	ATP-dependent helicase
C3V41_10925	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C3V41_10930	ENOG4107YVI	ribose 5-phosphate isomerase
C3V41_10935	ENOG4108UGD	Serine Threonine protein kinase
C3V41_10995	ENOG4107S03	uridine kinase
C3V41_11050	ENOG4105EN6	Membrane
C3V41_11105	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C3V41_11140	ENOG4105M6F	mutator MutT protein
C3V41_11175	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C3V41_11205	ENOG4105E2D	ec 3.2.1.52
C3V41_11215	ENOG4108DBC	nitroreductase
C3V41_11240	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
C3V41_11245	ENOG4108IXY	short-chain dehydrogenase reductase
C3V41_11255	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C3V41_11270	ENOG4107RCW	fructose-bisphosphate aldolase
C3V41_11280	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C3V41_11315	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_11370	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C3V41_11380	ENOG4105C12	Phosphoribosylglycinamide synthetase
C3V41_11395	ENOG4105C8V	SAICAR synthetase
C3V41_11430	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C3V41_11440	ENOG41088YS	Glycosyl transferase (Group 1
C3V41_11455	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C3V41_11470	ENOG4107XZQ	multidrug resistance protein
C3V41_11495	ENOG4105VE1	Phosphatidylcholine synthase
C3V41_11515	ENOG4105D82	Glutamate dehydrogenase
C3V41_11520	ENOG4105E98	transcriptional regulator DeoR family
C3V41_11530	ENOG4105DM4	PTS System
C3V41_11550	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C3V41_11575	ENOG4105BZ1	(ABC) transporter
C3V41_11620	ENOG4105C1J	atp-dependent rna helicase
C3V41_11685	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C3V41_11695	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C3V41_11710	ENOG4108IQK	o-acetylhomoserine
C3V41_11715	ENOG4105DWV	Homoserine O-trans-acetylase
C3V41_11725	ENOG4105F0N	pyrophosphate phospho-hydrolase
C3V41_11820	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C3V41_11825	ENOG4105EUJ	GTP cyclohydrolase i
C3V41_11870	ENOG4105WH1	Two component transcriptional regulator luxr family
C3V41_11875	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_11880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_11885	ENOG4105EEI	dihydropteroate synthase
C3V41_11920	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C3V41_11950	ENOG4105DUX	Transporter
C3V41_11955	ENOG4105DEI	Mannitol dehydrogenase
C3V41_11960	ENOG41080R8	Conserved Protein
C3V41_11970	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C3V41_11975	ENOG4106F60	Histidine kinase
C3V41_11980	ENOG4105F44	Two component transcriptional regulator, winged helix family
C3V41_11995	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_12000	ENOG4107RBB	ABC transporter, permease
C3V41_12005	ENOG4105DAA	L-lactate
C3V41_12010	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
C3V41_12015	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
C3V41_12020	ENOG4105P52	geranylgeranyl reductase
C3V41_12030	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3V41_12035	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C3V41_12040	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3V41_12050	ENOG4107QIZ	NADH dehydrogenase
C3V41_12055	ENOG4108IEH	NADH dehydrogenase subunit g
C3V41_12060	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C3V41_12065	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3V41_12075	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3V41_12080	ENOG4105D65	subunit l
C3V41_12090	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C3V41_12100	ENOG4105PWE	CRISPR-associated protein cas2
C3V41_12105	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
C3V41_12115	ENOG4108VWQ	crispr-associated protein
C3V41_12120	ENOG41060M0	Crispr-associated protein, cse4 family
C3V41_12160	ENOG41063PX	domain protein
C3V41_12180	ENOG4108URH	decarboxylase
C3V41_12185	ENOG4105DJZ	UPF0182 protein
C3V41_12195	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
C3V41_12200	ENOG4107RPQ	ABC transporter
C3V41_12205	ENOG4107RBD	ABC, transporter
C3V41_12210	ENOG4105DIK	(ABC) transporter
C3V41_12215	ENOG4107SIG	periplasmic solute binding protein
C3V41_12220	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C3V41_12245	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3V41_12250	ENOG4107RBB	ABC transporter, permease
C3V41_12275	ENOG4105CZN	Potassium uptake protein
C3V41_12290	ENOG4107R4N	Cell wall formation (By similarity)
C3V41_12300	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C3V41_12315	ENOG4105CIG	ABC transporter
C3V41_12330	ENOG4107NHD	transcriptional regulator
C3V41_12345	ENOG4108IUX	(ABC) transporter
C3V41_12350	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C3V41_12370	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C3V41_12385	ENOG4105BZU	Histidine kinase
C3V41_12390	ENOG4105KCT	ABC transporter
C3V41_12395	ENOG4108M15	ABC transporter
C3V41_12405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C3V41_12415	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
C3V41_12420	ENOG4105BZ1	(ABC) transporter
C3V41_12425	ENOG4105BZ1	(ABC) transporter
C3V41_12435	ENOG4105C31	Tryptophanyl-tRNA synthetase
C3V41_12455	ENOG4105C10	Electron transfer flavoprotein
C3V41_12460	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
C3V41_12470	ENOG4105DEG	Vwa containing coxe family protein
C3V41_12490	ENOG4108KDT	Molybdate metabolism regulator
C3V41_12495	ENOG4108KDT	Molybdate metabolism regulator
C3V41_12505	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C3V41_12520	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C3V41_12550	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C3V41_12580	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C3V41_12585	ENOG4108UVJ	appr-1-p processing domain protein
C3V41_12595	ENOG4105K7K	Transcriptional regulator
C3V41_12605	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C3V41_12640	ENOG4105DQX	Zinc finger domain
C3V41_12655	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C3V41_12675	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)