locus-tag	class	description
JG540_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JG540_00010	COG0592	DNA-directed DNA polymerase activity
JG540_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JG540_00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JG540_00025	COG0187	DNA topoisomerase II activity
JG540_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JG540_00070	COG0656	L-ascorbic acid biosynthetic process
JG540_00095	COG3764	Sortase (surface protein transpeptidase)
JG540_00105	COG0515	serine threonine protein kinase
JG540_00110	COG0515	serine threonine protein kinase
JG540_00115	COG0768	penicillin binding
JG540_00130	COG1716	ATPase activity
JG540_00145	COG1716	ATPase activity
JG540_00160	COG1966	Carbon starvation protein
JG540_00165	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JG540_00170	COG2985	domain, Protein
JG540_00170	COG0569	domain protein
JG540_00175	COG2855	membrane
JG540_00185	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JG540_00190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JG540_00200	COG0789	Transcriptional regulator
JG540_00205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG540_00210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JG540_00215	COG0360	Binds together with S18 to 16S ribosomal RNA
JG540_00220	COG0629	single-stranded DNA binding
JG540_00225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JG540_00230	COG0359	binds to the 23S rRNA
JG540_00240	COG0305	Participates in initiation and elongation during chromosome replication
JG540_00250	COG1196	nuclear chromosome segregation
JG540_00255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JG540_00270	COG2267	carboxylic ester hydrolase activity
JG540_00285	COG2267	carboxylic ester hydrolase activity
JG540_00290	COG0628	permease
JG540_00295	COG0351	phosphomethylpyrimidine kinase
JG540_00305	COG1760	l-serine dehydratase
JG540_00310	COG4115	mRNA cleavage
JG540_00315	COG2161	toxin-antitoxin pair type II binding
JG540_00325	COG3550	peptidyl-serine autophosphorylation
JG540_00330	COG1302	Protein conserved in bacteria
JG540_00355	COG1595	DNA-templated transcription, initiation
JG540_00380	COG0366	Alpha amylase catalytic
JG540_00405	COG1827	regulation of RNA biosynthetic process
JG540_00415	COG1780	Probably involved in ribonucleotide reductase function
JG540_00420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JG540_00445	COG1468	defense response to virus
JG540_00445	COG1518	maintenance of DNA repeat elements
JG540_00455	COG0596	Alpha beta hydrolase
JG540_00475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JG540_00535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JG540_00550	COG2011	ABC-type metal ion transport system permease component
JG540_00560	COG2885	chlorophyll binding
JG540_00585	COG1404	Belongs to the peptidase S8 family
JG540_00590	COG2181	nitrate reductase activity
JG540_00590	COG0247	lactate metabolic process
JG540_00625	COG3842	ATPase activity
JG540_00630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JG540_00635	COG0601	transmembrane transport
JG540_00700	COG3842	ATPase activity
JG540_00710	COG1840	ABC-type Fe3 transport system, periplasmic component
JG540_00715	COG0745	RESPONSE REGULATOR receiver
JG540_00720	COG5002	protein histidine kinase activity
JG540_00855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG540_00860	COG1120	ATPase activity
JG540_00865	COG4585	Histidine kinase
JG540_00870	COG2197	response regulator
JG540_00880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JG540_00890	COG0443	Heat shock 70 kDa protein
JG540_00895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JG540_00900	COG0484	heat shock protein binding
JG540_00905	COG0789	Transcriptional regulator
JG540_00950	COG0542	response to heat
JG540_00960	COG0584	glycerophosphoryl diester phosphodiesterase
JG540_01005	COG3588	fructose-bisphosphate aldolase
JG540_01010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JG540_01015	COG0346	lactoylglutathione lyase activity
JG540_01020	COG0215	cysteine-tRNA ligase activity
JG540_01025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG540_01045	COG3842	ATPase activity
JG540_01065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JG540_01090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JG540_01095	COG1643	Atp-dependent helicase
JG540_01110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JG540_01115	COG3142	Participates in the control of copper homeostasis
JG540_01120	COG4988	ABC transporter
JG540_01125	COG1132	(ABC) transporter
JG540_01130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JG540_01135	COG2860	membrane
JG540_01150	COG1674	ftsk spoiiie
JG540_01235	COG0714	Associated with various cellular activities
JG540_01285	COG0717	Belongs to the dCTP deaminase family
JG540_01315	COG0778	Nitroreductase
JG540_01335	COG1175	transmembrane transport
JG540_01340	COG0395	ABC-type sugar transport system, permease component
JG540_01345	COG0300	oxidoreductase activity
JG540_01360	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JG540_01370	COG0785	Cytochrome C biogenesis protein
JG540_01375	COG1333	cytochrome c biogenesis protein
JG540_01380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JG540_01385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG540_01390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JG540_01395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG540_01400	COG0191	fructose-bisphosphate aldolase activity
JG540_01430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JG540_01450	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JG540_01485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JG540_01490	COG0737	Belongs to the 5'-nucleotidase family
JG540_01490	COG1525	nuclease
JG540_01490	COG4085	toxin activity
JG540_01500	COG0557	exoribonuclease II activity
JG540_01505	COG0577	efflux transmembrane transporter activity
JG540_01505	COG1136	(ABC) transporter
JG540_01520	COG1309	transcriptional regulator
JG540_01545	COG1472	Belongs to the glycosyl hydrolase 3 family
JG540_01550	COG0577	efflux transmembrane transporter activity
JG540_01555	COG1136	(ABC) transporter
JG540_01555	COG0577	efflux transmembrane transporter activity
JG540_01610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG540_01645	COG0513	Belongs to the DEAD box helicase family
JG540_01680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JG540_01685	COG0494	nUDIX hydrolase
JG540_01685	COG0406	alpha-ribazole phosphatase activity
JG540_01695	COG0745	RESPONSE REGULATOR receiver
JG540_01710	COG0354	folic acid binding
JG540_01725	COG1490	D-aminoacyl-tRNA deacylase activity
JG540_01735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JG540_01735	COG0574	Belongs to the PEP-utilizing enzyme family
JG540_01750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JG540_01755	COG2873	o-acetylhomoserine
JG540_01760	COG3883	PFAM NLP P60 protein
JG540_01760	COG0791	NLP P60 protein
JG540_01765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JG540_01770	COG2027	D-alanyl-D-alanine carboxypeptidase
JG540_01850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JG540_01855	COG0302	gtp cyclohydrolase
JG540_01875	COG1136	(ABC) transporter
JG540_01875	COG0577	efflux transmembrane transporter activity
JG540_01885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JG540_01910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JG540_01915	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JG540_01920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JG540_01940	COG1556	Lactate utilization protein
JG540_01945	COG1139	Iron-sulfur cluster binding protein
JG540_01950	COG0247	lactate metabolic process
JG540_01960	COG1620	l-lactate permease
JG540_01970	COG0446	pyridine nucleotide-disulphide oxidoreductase
JG540_01975	COG1937	Protein conserved in bacteria
JG540_01980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JG540_01985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JG540_01990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JG540_01995	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
JG540_02000	COG0247	lactate metabolic process
JG540_02030	COG2017	converts alpha-aldose to the beta-anomer
JG540_02035	COG0569	domain protein
JG540_02040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG540_02055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JG540_02065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JG540_02075	COG1115	amino acid carrier protein
JG540_02080	COG0436	Aminotransferase
JG540_02095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JG540_02100	COG0250	Participates in transcription elongation, termination and antitermination
JG540_02105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JG540_02110	COG0081	regulation of translation
JG540_02115	COG2885	chlorophyll binding
JG540_02140	COG0515	serine threonine protein kinase
JG540_02145	COG2885	chlorophyll binding
JG540_02150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JG540_02155	COG0222	ribosome binding
JG540_02165	COG0085	RNA polymerase activity
JG540_02170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JG540_02180	COG0714	Associated with various cellular activities
JG540_02200	COG0631	protein serine/threonine phosphatase activity
JG540_02220	COG1674	ftsk spoiiie
JG540_02220	COG0433	COG0433 Predicted ATPase
JG540_02305	COG1100	Small GTP-binding protein
JG540_02310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JG540_02315	COG0049	tRNA binding
JG540_02320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JG540_02325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JG540_02380	COG0051	transcription antitermination factor activity, RNA binding
JG540_02385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JG540_02390	COG0088	Forms part of the polypeptide exit tunnel
JG540_02395	COG0089	rRNA binding
JG540_02400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JG540_02405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JG540_02410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JG540_02415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JG540_02420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JG540_02425	COG0255	Belongs to the universal ribosomal protein uL29 family
JG540_02430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JG540_02435	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JG540_02440	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JG540_02445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JG540_02450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JG540_02455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JG540_02460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JG540_02470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JG540_02475	COG1841	ribosomal large subunit assembly
JG540_02480	COG0200	Binds to the 23S rRNA
JG540_02490	COG0563	adenylate kinase activity
JG540_02510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JG540_02515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JG540_02520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JG540_02525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JG540_02530	COG0202	RNA polymerase activity
JG540_02535	COG0203	ribosomal protein L17
JG540_02555	COG0101	tRNA pseudouridine synthase activity
JG540_02560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JG540_02575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG540_02580	COG1072	(Pantothenic acid kinase))
JG540_02590	COG0736	holo-[acyl-carrier-protein] synthase activity
JG540_02600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JG540_02605	COG0802	atpase or kinase
JG540_02620	COG0456	acetyltransferase
JG540_02630	COG1053	succinate dehydrogenase
JG540_02635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JG540_02660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JG540_02670	COG2949	membrane
JG540_02675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JG540_02705	COG0516	GMP reductase activity
JG540_02715	COG0328	RNA-DNA hybrid ribonuclease activity
JG540_02720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JG540_02725	COG0280	phosphate acetyltransferase
JG540_02725	COG0857	belongs to the CobB CobQ family
JG540_02730	COG0673	inositol 2-dehydrogenase activity
JG540_02735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JG540_02750	COG2188	Transcriptional regulator
JG540_02755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JG540_02765	COG3718	enzyme involved in inositol metabolism
JG540_02790	COG1172	Belongs to the binding-protein-dependent transport system permease family
JG540_02795	COG1879	ABC-type sugar transport system periplasmic component
JG540_02815	COG0519	Catalyzes the synthesis of GMP from XMP
JG540_02815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JG540_02840	COG1335	isochorismatase
JG540_02845	COG1136	(ABC) transporter
JG540_02875	COG2197	response regulator
JG540_02895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JG540_02905	COG0356	it plays a direct role in the translocation of protons across the membrane
JG540_02910	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JG540_02915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JG540_02920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JG540_02920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JG540_02925	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JG540_02930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JG540_02935	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JG540_02940	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JG540_02950	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JG540_02960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JG540_02985	COG1518	maintenance of DNA repeat elements
JG540_03000	COG1857	crispr-associated protein
JG540_03020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JG540_03025	COG0254	rRNA binding
JG540_03030	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JG540_03035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JG540_03040	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JG540_03055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JG540_03060	COG1254	Belongs to the acylphosphatase family
JG540_03070	COG0577	efflux transmembrane transporter activity
JG540_03075	COG1136	(ABC) transporter
JG540_03075	COG0577	efflux transmembrane transporter activity
JG540_03085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JG540_03090	COG1349	DNA-binding transcription factor activity
JG540_03115	COG2195	Cleaves the N-terminal amino acid of tripeptides
JG540_03125	COG0803	Belongs to the bacterial solute-binding protein 9 family
JG540_03130	COG1121	(ABC) transporter
JG540_03145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JG540_03155	COG1611	Belongs to the LOG family
JG540_03185	COG2239	Acts as a magnesium transporter
JG540_03195	COG1082	Xylose isomerase domain protein TIM barrel
JG540_03200	COG1230	cation diffusion facilitator family transporter
JG540_03210	COG0006	proline dipeptidase activity
JG540_03220	COG2095	MarC family integral membrane protein
JG540_03230	COG0513	Belongs to the DEAD box helicase family
JG540_03245	COG2315	Protein conserved in bacteria
JG540_03250	COG0114	fumarate hydratase activity
JG540_03255	COG1064	alcohol dehydrogenase
JG540_03270	COG0517	IMP dehydrogenase activity
JG540_03270	COG1125	glycine betaine transport
JG540_03275	COG1174	glycine betaine transport
JG540_03295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JG540_03300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JG540_03330	COG1674	ftsk spoiiie
JG540_03335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JG540_03345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JG540_03350	COG0154	amidase activity
JG540_03355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JG540_03385	COG2985	domain, Protein
JG540_03385	COG0569	domain protein
JG540_03400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JG540_03405	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JG540_03415	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JG540_03420	COG0473	3-isopropylmalate dehydrogenase activity
JG540_03435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JG540_03440	COG0489	protein tyrosine kinase activity
JG540_03440	COG3206	protein involved in exopolysaccharide biosynthesis
JG540_03465	COG3475	LICD family
JG540_03495	COG1316	TRANSCRIPTIONal
JG540_03510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JG540_03560	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JG540_03565	COG1716	ATPase activity
JG540_03565	COG0842	Transport permease protein
JG540_03565	COG1131	(ABC) transporter
JG540_03590	COG2884	Cell division ATP-binding protein ftsE
JG540_03595	COG2177	Part of the ABC transporter FtsEX involved in
JG540_03615	COG2233	PERMEase
JG540_03635	COG2186	Transcriptional regulator
JG540_03640	COG0747	negative chemotaxis
JG540_03650	COG0444	Belongs to the ABC transporter superfamily
JG540_03655	COG4608	Belongs to the ABC transporter superfamily
JG540_03660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JG540_03665	COG1940	carbohydrate kinase activity
JG540_03670	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JG540_03690	COG0363	glucosamine-6-phosphate deaminase activity
JG540_03710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JG540_03720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JG540_03725	COG1234	tRNA 3'-trailer cleavage
JG540_03750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JG540_03755	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JG540_03810	COG3304	Inner membrane component domain
JG540_03815	COG1136	(ABC) transporter
JG540_03835	COG1115	amino acid carrier protein
JG540_03840	COG1115	amino acid carrier protein
JG540_03845	COG1115	amino acid carrier protein
JG540_03850	COG1115	amino acid carrier protein
JG540_03855	COG0179	Fumarylacetoacetate (FAA) hydrolase
JG540_03865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JG540_03900	COG1674	ftsk spoiiie
JG540_03915	COG1058	Belongs to the CinA family
JG540_03915	COG1546	Belongs to the CinA family
JG540_03920	COG1396	sequence-specific DNA binding
JG540_03930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JG540_03950	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JG540_03955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JG540_03965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JG540_03970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JG540_03975	COG1114	Component of the transport system for branched-chain amino acids
JG540_03985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JG540_04000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JG540_04010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JG540_04020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JG540_04035	COG0318	PFAM AMP-dependent synthetase and ligase
JG540_04055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JG540_04065	COG2001	Belongs to the MraZ family
JG540_04070	COG0275	rRNA processing
JG540_04080	COG0768	penicillin binding
JG540_04090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JG540_04095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JG540_04100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JG540_04105	COG0772	Belongs to the SEDS family
JG540_04115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JG540_04125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JG540_04130	COG1496	oxidoreductase activity
JG540_04135	COG1799	cell septum assembly
JG540_04145	COG3599	regulation of cell shape
JG540_04150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JG540_04165	COG0587	DNA-directed DNA polymerase activity
JG540_04200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JG540_04215	COG0131	Imidazoleglycerol-phosphate dehydratase
JG540_04235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JG540_04240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JG540_04255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JG540_04260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JG540_04270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG540_04275	COG1263	PTS System
JG540_04275	COG2190	(PTS) system
JG540_04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG540_04285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JG540_04290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG540_04290	COG0072	phenylalanine-tRNA ligase activity
JG540_04300	COG1438	arginine binding
JG540_04305	COG0137	argininosuccinate synthase activity
JG540_04315	COG0165	Argininosuccinate lyase
JG540_04320	COG2094	Belongs to the DNA glycosylase MPG family
JG540_04335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JG540_04360	COG0647	UMP catabolic process
JG540_04375	COG0497	DNA recombination
JG540_04405	COG0494	nUDIX hydrolase
JG540_04425	COG0396	ATPase activity
JG540_04435	COG0822	iron-sulfur transferase activity
JG540_04440	COG2151	metal-sulfur cluster biosynthetic enzyme
JG540_04460	COG4589	Belongs to the CDS family
JG540_04470	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JG540_04485	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JG540_04495	COG0167	dihydroorotate dehydrogenase activity
JG540_04510	COG1929	Belongs to the glycerate kinase type-1 family
JG540_04520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JG540_04525	COG0358	DNA primase activity
JG540_04560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JG540_04580	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JG540_04600	COG0753	catalase activity
JG540_04630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JG540_04640	COG3022	response to hydroperoxide
JG540_04665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JG540_04670	COG0174	glutamine synthetase
JG540_04675	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JG540_04685	COG1126	abc transporter atp-binding protein
JG540_04690	COG0765	amino acid transport
JG540_04695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG540_04710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JG540_04715	COG0321	lipoyl(octanoyl) transferase activity
JG540_04720	COG0515	serine threonine protein kinase
JG540_04735	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG540_04740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG540_04745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JG540_04765	COG1131	(ABC) transporter
JG540_04785	COG1882	Formate acetyltransferase
JG540_04800	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JG540_04825	COG1794	racemase activity, acting on amino acids and derivatives
JG540_04835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JG540_04845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JG540_04850	COG1560	Kdo2-lipid A biosynthetic process
JG540_04855	COG0438	transferase activity, transferring glycosyl groups
JG540_04870	COG0494	nUDIX hydrolase
JG540_04875	COG0217	transcriptional regulatory protein
JG540_04880	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JG540_04885	COG0632	four-way junction helicase activity
JG540_04890	COG2255	four-way junction helicase activity
JG540_04900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG540_04905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG540_04910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JG540_04915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JG540_04925	COG1196	nuclear chromosome segregation
JG540_04930	COG2226	methyltransferase
JG540_04950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JG540_04980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JG540_04990	COG0009	L-threonylcarbamoyladenylate synthase
JG540_04995	COG2409	Drug exporters of the RND superfamily
JG540_05005	COG0730	response to heat
JG540_05010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JG540_05020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JG540_05025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JG540_05030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JG540_05035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JG540_05055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JG540_05060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JG540_05070	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JG540_05075	COG0540	Belongs to the ATCase OTCase family
JG540_05080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JG540_05090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JG540_05095	COG0284	orotidine-5'-phosphate decarboxylase activity
JG540_05105	COG0194	GDP metabolic process
JG540_05110	COG1758	RNA polymerase activity
JG540_05120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JG540_05130	COG1470	cell adhesion involved in biofilm formation
JG540_05130	COG0366	Alpha amylase catalytic
JG540_05140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JG540_05150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JG540_05155	COG4770	biotin carboxylase activity
JG540_05160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JG540_05165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JG540_05180	COG2376	Dihydroxyacetone kinase
JG540_05185	COG1461	Dihydroxyacetone kinase
JG540_05190	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JG540_05190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JG540_05190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JG540_05195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JG540_05205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JG540_05210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JG540_05215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JG540_05220	COG0140	phosphoribosyl-ATP diphosphatase activity
JG540_05225	COG1105	Belongs to the carbohydrate kinase PfkB family
JG540_05245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JG540_05250	COG0805	protein transport
JG540_05270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JG540_05275	COG1216	Glycosyl transferase, family 2
JG540_05285	COG0205	6-phosphofructokinase activity
JG540_05295	COG0577	efflux transmembrane transporter activity
JG540_05300	COG1136	(ABC) transporter
JG540_05315	COG2190	(PTS) system
JG540_05315	COG1263	PTS System
JG540_05315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG540_05320	COG1621	beta-fructofuranosidase activity
JG540_05325	COG0443	Heat shock 70 kDa protein
JG540_05345	COG1716	ATPase activity
JG540_05375	COG0662	Cupin 2, conserved barrel domain protein
JG540_05395	COG0166	Belongs to the GPI family
JG540_05415	COG1160	GTP binding
JG540_05430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JG540_05450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JG540_05455	COG0149	triose-phosphate isomerase activity
JG540_05465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JG540_05470	COG1481	regulation of sporulation
JG540_05480	COG1660	Displays ATPase and GTPase activities
JG540_05490	COG2190	(PTS) system
JG540_05490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG540_05490	COG1263	PTS System
JG540_05495	COG0322	excinuclease ABC activity
JG540_05545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG540_05555	COG0556	nucleotide-excision repair
JG540_05565	COG0237	dephospho-CoA kinase activity
JG540_05570	COG0539	negative regulation of cytoplasmic translation
JG540_05580	COG2050	protein possibly involved in aromatic compounds catabolism
JG540_05600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JG540_05605	COG0134	indole-3-glycerol-phosphate synthase activity
JG540_05610	COG1297	OPT oligopeptide transporter protein
JG540_05630	COG0107	imidazoleglycerol-phosphate synthase activity
JG540_05645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JG540_05655	COG4122	O-methyltransferase activity
JG540_05660	COG1222	aaa ATPase
JG540_05675	COG1994	Peptidase M50
JG540_05675	COG0517	IMP dehydrogenase activity
JG540_05685	COG0656	L-ascorbic acid biosynthetic process
JG540_05695	COG0483	inositol monophosphate 1-phosphatase activity
JG540_05700	COG1609	Transcriptional regulator
JG540_05730	COG0676	glucose-6-phosphate 1-epimerase activity
JG540_05750	COG0833	amino acid
JG540_05770	COG0671	phosphoesterase, PA-phosphatase related
JG540_05785	COG1881	PFAM PEBP family protein
JG540_05790	COG4221	oxidoreductase activity
JG540_05795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JG540_05805	COG0823	Involved in the tonB-independent uptake of proteins
JG540_05810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JG540_05815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JG540_05825	COG0569	domain protein
JG540_05870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JG540_05900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JG540_05905	COG0142	geranyltranstransferase activity
JG540_05910	COG0515	serine threonine protein kinase
JG540_05910	COG2815	serine threonine protein kinase
JG540_05915	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JG540_05965	COG0488	(ABC) transporter
JG540_06005	COG1119	ATPase activity
JG540_06015	COG0297	glycogen (starch) synthase activity
JG540_06020	COG0745	RESPONSE REGULATOR receiver
JG540_06025	COG2205	protein histidine kinase activity
JG540_06035	COG2885	chlorophyll binding
JG540_06045	COG0560	Phosphoserine phosphatase
JG540_06055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JG540_06075	COG0423	glycine-tRNA ligase activity
JG540_06085	COG0803	Belongs to the bacterial solute-binding protein 9 family
JG540_06090	COG1121	(ABC) transporter
JG540_06095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JG540_06105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JG540_06105	COG0519	Catalyzes the synthesis of GMP from XMP
JG540_06110	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JG540_06115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JG540_06120	COG1381	Involved in DNA repair and RecF pathway recombination
JG540_06125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JG540_06130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JG540_06140	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JG540_06170	COG0484	heat shock protein binding
JG540_06175	COG1420	regulation of RNA biosynthetic process
JG540_06190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JG540_06210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JG540_06215	COG0481	GTPase activity
JG540_06225	COG2197	response regulator
JG540_06230	COG4585	Histidine kinase
JG540_06230	COG4585	Histidine kinase
JG540_06255	COG0268	Binds directly to 16S ribosomal RNA
JG540_06260	COG4868	Belongs to the UPF0371 family
JG540_06265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG540_06280	COG1555	photosystem II stabilization
JG540_06285	COG1307	EDD domain protein, DegV family
JG540_06290	COG0433	COG0433 Predicted ATPase
JG540_06295	COG0495	leucyl-tRNA aminoacylation
JG540_06305	COG1321	iron dependent repressor
JG540_06330	COG0733	neurotransmitter:sodium symporter activity
JG540_06360	COG0588	phosphoglycerate mutase activity
JG540_06365	COG0799	negative regulation of ribosome biogenesis
JG540_06375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JG540_06395	COG1349	DNA-binding transcription factor activity
JG540_06400	COG5426	von Willebrand factor, type A
JG540_06410	COG0438	transferase activity, transferring glycosyl groups
JG540_06415	COG1132	(ABC) transporter
JG540_06425	COG5002	protein histidine kinase activity
JG540_06430	COG0745	RESPONSE REGULATOR receiver
JG540_06440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JG540_06445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JG540_06450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JG540_06455	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JG540_06460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JG540_06470	COG1530	ribonuclease E activity
JG540_06475	COG1271	oxidase subunit
JG540_06480	COG1294	oxidase, subunit
JG540_06485	COG4988	ABC transporter
JG540_06490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JG540_06505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JG540_06510	COG0571	ribonuclease III activity
JG540_06535	COG0738	Major facilitator superfamily
JG540_06545	COG1070	Carbohydrate kinase
JG540_06555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JG540_06555	COG0515	serine threonine protein kinase
JG540_06565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JG540_06595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JG540_06610	COG0235	Class ii aldolase
JG540_06615	COG0133	tryptophan synthase activity
JG540_06620	COG2890	protein-(glutamine-N5) methyltransferase activity
JG540_06625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JG540_06630	COG1461	Dihydroxyacetone kinase
JG540_06635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JG540_06640	COG2211	Major facilitator Superfamily
JG540_06660	COG1181	Belongs to the D-alanine--D-alanine ligase family
JG540_06670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JG540_06680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JG540_06685	COG0066	3-isopropylmalate dehydratase activity
JG540_06705	COG0612	Peptidase, M16
JG540_06710	COG1185	polyribonucleotide nucleotidyltransferase activity
JG540_06715	COG1454	alcohol dehydrogenase
JG540_06730	COG0196	riboflavin kinase activity
JG540_06740	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JG540_06760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JG540_06775	COG0779	Required for maturation of 30S ribosomal subunits
JG540_06785	COG0442	prolyl-tRNA aminoacylation
JG540_06790	COG2501	S4 domain
JG540_06795	COG0456	acetyltransferase
JG540_06800	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JG540_06805	COG0750	zinc metalloprotease
JG540_06810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JG540_06820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JG540_06830	COG0233	cytoplasmic translational termination
JG540_06835	COG0528	UMP kinase activity
JG540_06840	COG0534	Mate efflux family protein
JG540_06845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JG540_06850	COG0052	Belongs to the universal ribosomal protein uS2 family
JG540_06860	COG4974	Belongs to the 'phage' integrase family
JG540_06885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JG540_06890	COG0681	Belongs to the peptidase S26 family
JG540_06905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JG540_06915	COG1837	Belongs to the UPF0109 family
JG540_06925	COG1131	(ABC) transporter
JG540_06935	COG4585	Histidine kinase
JG540_06940	COG2197	response regulator
JG540_06945	COG1115	amino acid carrier protein
JG540_06970	COG1196	nuclear chromosome segregation
JG540_06980	COG1131	(ABC) transporter
JG540_06985	COG2197	response regulator
JG540_07000	COG4152	abc transporter atp-binding protein
JG540_07010	COG0105	UTP biosynthetic process
JG540_07015	COG0285	dihydrofolate synthase activity
JG540_07040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JG540_07060	COG1605	Chorismate mutase
JG540_07060	COG0287	Prephenate dehydrogenase
JG540_07065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JG540_07070	COG0740	serine-type endopeptidase activity
JG540_07080	COG0544	peptidyl-prolyl cis-trans isomerase activity
JG540_07140	COG1739	Uncharacterized protein family UPF0029
JG540_07150	COG1045	serine acetyltransferase
JG540_07165	COG0698	ribose 5-phosphate isomerase
JG540_07170	COG3590	peptidase
JG540_07190	COG1263	PTS System
JG540_07195	COG2188	Transcriptional regulator
JG540_07200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JG540_07215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JG540_07235	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JG540_07240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JG540_07250	COG0813	purine-nucleoside phosphorylase activity
JG540_07255	COG2390	Transcriptional regulator
JG540_07270	COG1079	Belongs to the binding-protein-dependent transport system permease family
JG540_07275	COG4603	Belongs to the binding-protein-dependent transport system permease family
JG540_07285	COG1744	ABC transporter substrate-binding protein PnrA-like
JG540_07290	COG0583	DNA-binding transcription factor activity
JG540_07365	COG1615	UPF0182 protein
JG540_07380	COG3480	Lon protease (S16) C-terminal proteolytic domain
JG540_07405	COG3583	domain protein
JG540_07405	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JG540_07410	COG0482	sulfurtransferase activity
JG540_07430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JG540_07455	COG0366	Alpha amylase catalytic
JG540_07460	COG3281	Trehalose synthase
JG540_07465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JG540_07485	COG0058	SHG alpha-glucan phosphorylase activity
JG540_07520	COG0395	ABC-type sugar transport system, permease component
JG540_07525	COG1175	transmembrane transport
JG540_07535	COG0039	L-malate dehydrogenase activity
JG540_07540	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JG540_07555	COG1122	ATPase activity
JG540_07575	COG0045	succinate-CoA ligase (ADP-forming) activity
JG540_07580	COG0205	6-phosphofructokinase activity
JG540_07585	COG0110	maltose O-acetyltransferase activity
JG540_07590	COG0366	Alpha amylase catalytic
JG540_07600	COG1175	transmembrane transport
JG540_07610	COG1940	carbohydrate kinase activity
JG540_07615	COG0778	Nitroreductase
JG540_07675	COG0714	Associated with various cellular activities
JG540_07680	COG3552	Protein containing von Willebrand factor type A (VWA) domain
JG540_07695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JG540_07700	COG0254	rRNA binding
JG540_07715	COG0701	Predicted permease
JG540_07730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JG540_07735	COG0840	transmembrane signaling receptor activity
JG540_07740	COG0083	homoserine kinase activity
JG540_07745	COG0460	homoserine dehydrogenase
JG540_07750	COG0019	diaminopimelate decarboxylase activity
JG540_07755	COG0018	arginyl-trna synthetase
JG540_07765	COG0584	glycerophosphoryl diester phosphodiesterase
JG540_07770	COG1196	nuclear chromosome segregation
JG540_07770	COG0741	lytic transglycosylase activity
JG540_07770	COG0739	heme binding
JG540_07790	COG0567	Dehydrogenase, E1 component
JG540_07790	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG540_07805	COG1595	DNA-templated transcription, initiation
JG540_07815	COG2838	Isocitrate dehydrogenase
JG540_07825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JG540_07830	COG1162	GTPase activity
JG540_07840	COG1222	aaa ATPase
JG540_07855	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JG540_07865	COG0483	inositol monophosphate 1-phosphatase activity
JG540_07870	COG1968	undecaprenyl-diphosphatase activity
JG540_07885	COG0420	3'-5' exonuclease activity
JG540_07890	COG0419	ATPase involved in DNA repair
JG540_07890	COG0419	ATPase involved in DNA repair
JG540_07890	COG0419	ATPase involved in DNA repair
JG540_07930	COG0653	protein targeting
JG540_07935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JG540_07940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JG540_07945	COG5401	PFAM Sporulation and spore germination
JG540_07950	COG5000	phosphorelay sensor kinase activity
JG540_07950	COG5002	protein histidine kinase activity
JG540_07955	COG0745	RESPONSE REGULATOR receiver
JG540_07975	COG0714	Associated with various cellular activities
JG540_07995	COG2835	tetraacyldisaccharide 4'-kinase activity
JG540_08030	COG1482	cell wall glycoprotein biosynthetic process
JG540_08040	COG0438	transferase activity, transferring glycosyl groups
JG540_08050	COG3475	LICD family
JG540_08055	COG3475	LICD family
JG540_08060	COG0697	spore germination
JG540_08065	COG4750	Nucleotidyl transferase
JG540_08080	COG0438	transferase activity, transferring glycosyl groups
JG540_08090	COG1216	Glycosyl transferase, family 2
JG540_08145	COG1088	dTDP-glucose 4,6-dehydratase activity
JG540_08190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JG540_08215	COG0745	RESPONSE REGULATOR receiver
JG540_08230	COG0424	maF-like protein
JG540_08235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JG540_08240	COG1846	Transcriptional regulator
JG540_08270	COG1666	GTP binding
JG540_08285	COG2197	response regulator
JG540_08290	COG4585	Histidine kinase
JG540_08295	COG0501	Belongs to the peptidase M48B family
JG540_08300	COG0686	Belongs to the AlaDH PNT family
JG540_08310	COG0142	geranyltranstransferase activity
JG540_08315	COG1007	ATP synthesis coupled electron transport
JG540_08330	COG0713	ATP synthesis coupled electron transport
JG540_08345	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JG540_08350	COG1034	ATP synthesis coupled electron transport
JG540_08355	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JG540_08365	COG0649	NAD binding
JG540_08370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG540_08375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JG540_08385	COG2226	methyltransferase
JG540_08400	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JG540_08405	COG4948	Mandelate Racemase Muconate Lactonizing
JG540_08410	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JG540_08475	COG1053	succinate dehydrogenase
JG540_08510	COG2720	vancomycin resistance protein
JG540_08515	COG1217	gtp-binding protein TYPA
JG540_08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JG540_08555	COG2267	carboxylic ester hydrolase activity
JG540_08565	COG4667	esterase of the alpha-beta hydrolase superfamily
JG540_08570	COG1362	aminopeptidase activity
JG540_08615	COG3422	double-strand break repair
JG540_08620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JG540_08630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JG540_08650	COG0012	GTP binding
JG540_08655	COG1322	Protein conserved in bacteria
JG540_08665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JG540_08670	COG1570	exodeoxyribonuclease VII activity
JG540_08675	COG1722	exodeoxyribonuclease VII activity
JG540_08685	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JG540_08690	COG0438	transferase activity, transferring glycosyl groups
JG540_08695	COG0438	transferase activity, transferring glycosyl groups
JG540_08700	COG1132	(ABC) transporter
JG540_08710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JG540_08720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JG540_08725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG540_08745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JG540_08750	COG0129	dihydroxy-acid dehydratase activity
JG540_08775	COG4585	Histidine kinase
JG540_08780	COG2197	response regulator
JG540_08785	COG0193	aminoacyl-tRNA hydrolase activity
JG540_08790	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JG540_08815	COG0148	phosphopyruvate hydratase activity
JG540_08875	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JG540_08875	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JG540_08890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JG540_08915	COG0714	Associated with various cellular activities
JG540_08950	COG0488	(ABC) transporter
JG540_08955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JG540_08960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JG540_08965	COG1388	LysM domain
JG540_08980	COG0084	hydrolase, TatD family'
JG540_08985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG540_09035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG540_09045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JG540_09055	COG1970	mechanosensitive ion channel activity
JG540_09095	COG2252	PERMEase
JG540_09115	COG1061	Type III restriction enzyme res subunit
JG540_09125	COG1842	Phage shock protein A
JG540_09135	COG0745	RESPONSE REGULATOR receiver
JG540_09140	COG2205	protein histidine kinase activity
JG540_09160	COG0459	protein refolding
JG540_09165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JG540_09170	COG1121	(ABC) transporter
JG540_09180	COG0803	Belongs to the bacterial solute-binding protein 9 family
JG540_09195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JG540_09200	COG1329	Transcriptional regulator
JG540_09205	COG0745	RESPONSE REGULATOR receiver
JG540_09210	COG5002	protein histidine kinase activity
JG540_09215	COG0588	phosphoglycerate mutase activity
JG540_09230	COG1113	amino acid transport
JG540_09235	COG0252	asparaginase activity
JG540_09245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JG540_09250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JG540_09260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JG540_09265	COG0549	Belongs to the carbamate kinase family
JG540_09270	COG1834	amidinotransferase
JG540_09280	COG0477	Major facilitator Superfamily
JG540_09290	COG1754	DNA topoisomerase type I activity
JG540_09290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JG540_09310	COG2890	protein-(glutamine-N5) methyltransferase activity
JG540_09355	COG0596	Alpha beta hydrolase
JG540_09385	COG1408	metallophosphoesterase
JG540_09395	COG1597	lipid kinase activity
JG540_09415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JG540_09415	COG3253	May function as heme-dependent peroxidase
JG540_09420	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JG540_09425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JG540_09430	COG0446	pyridine nucleotide-disulphide oxidoreductase
JG540_09445	COG0113	porphobilinogen synthase activity
JG540_09450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JG540_09455	COG0531	amino acid
JG540_09460	COG0803	Belongs to the bacterial solute-binding protein 9 family
JG540_09465	COG1121	(ABC) transporter
JG540_09470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JG540_09475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JG540_09485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG540_09515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JG540_09555	COG2233	PERMEase
JG540_09605	COG0590	tRNA wobble adenosine to inosine editing
JG540_09605	COG0037	tRNA processing
JG540_09610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JG540_09615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JG540_09635	COG1132	(ABC) transporter
JG540_09640	COG1132	(ABC) transporter
JG540_09660	COG0471	metal ion transport
JG540_09685	COG0395	ABC-type sugar transport system, permease component
JG540_09690	COG1175	transmembrane transport
JG540_09710	COG1609	Transcriptional regulator
JG540_09715	COG1653	transport
JG540_09720	COG0560	Phosphoserine phosphatase
JG540_09725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JG540_09750	COG5444	nuclease activity
JG540_09765	COG1597	lipid kinase activity
JG540_09770	COG0477	Major facilitator Superfamily
JG540_09775	COG0077	Prephenate dehydratase
JG540_09830	COG0251	oxidation-reduction process
JG540_09850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JG540_09855	COG1950	PFAM Membrane protein of
JG540_09885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JG540_09895	COG1609	Transcriptional regulator
JG540_09915	COG1175	transmembrane transport
JG540_09920	COG0395	ABC-type sugar transport system, permease component
JG540_10000	COG1131	(ABC) transporter
JG540_10020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JG540_10020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JG540_10070	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JG540_10070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JG540_10110	COG0737	Belongs to the 5'-nucleotidase family
JG540_10120	COG0617	tRNA 3'-terminal CCA addition
JG540_10135	COG0728	peptidoglycan biosynthetic process
JG540_10140	COG0492	ferredoxin-NADP+ reductase activity
JG540_10145	COG3118	belongs to the thioredoxin family
JG540_10155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG540_10160	COG1181	Belongs to the D-alanine--D-alanine ligase family
JG540_10175	COG0357	Ribosomal RNA small subunit methyltransferase G
JG540_10185	COG0706	membrane insertase activity
JG540_10190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JG540_10195	COG0594	ribonuclease P activity
JG540_10200	COG0230	Belongs to the bacterial ribosomal protein bL34 family