AFR_00955 ac43a208a89e701cdf670c295d26caae 392 Pfam PF13439 Glycosyltransferase Family 4 27 194 1.8E-18 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_00955 ac43a208a89e701cdf670c295d26caae 392 Pfam PF00534 Glycosyl transferases group 1 210 358 2.0E-23 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_00955 ac43a208a89e701cdf670c295d26caae 392 Gene3D G3DSA:3.40.50.2000 12 208 2.0E-27 T 12-10-2018 AFR_00955 ac43a208a89e701cdf670c295d26caae 392 Gene3D G3DSA:3.40.50.2000 209 364 4.1E-31 T 12-10-2018 AFR_00955 ac43a208a89e701cdf670c295d26caae 392 SUPERFAMILY SSF53756 14 381 3.45E-68 T 12-10-2018 AFR_37485 0cb986432fcd3e13df71841440134739 435 SUPERFAMILY SSF51735 7 161 6.79E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37485 0cb986432fcd3e13df71841440134739 435 PIRSF PIRSF000098 5 434 1.4E-151 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFR_37485 0cb986432fcd3e13df71841440134739 435 Pfam PF01842 ACT domain 358 419 4.9E-10 T 12-10-2018 IPR002912 ACT domain AFR_37485 0cb986432fcd3e13df71841440134739 435 Gene3D G3DSA:3.30.70.260 351 422 7.7E-142 T 12-10-2018 AFR_37485 0cb986432fcd3e13df71841440134739 435 Pfam PF00742 Homoserine dehydrogenase 140 323 5.7E-65 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFR_37485 0cb986432fcd3e13df71841440134739 435 Gene3D G3DSA:3.30.360.10 139 350 7.7E-142 T 12-10-2018 AFR_37485 0cb986432fcd3e13df71841440134739 435 SUPERFAMILY SSF55347 140 310 4.45E-51 T 12-10-2018 AFR_37485 0cb986432fcd3e13df71841440134739 435 Gene3D G3DSA:3.40.50.720 8 342 7.7E-142 T 12-10-2018 AFR_37485 0cb986432fcd3e13df71841440134739 435 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 186 208 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFR_37485 0cb986432fcd3e13df71841440134739 435 SUPERFAMILY SSF55021 354 425 3.5E-11 T 12-10-2018 AFR_37485 0cb986432fcd3e13df71841440134739 435 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 14 132 5.0E-21 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 SUPERFAMILY SSF52540 1070 1254 2.55E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 749 1320 1.2E-222 T 12-10-2018 IPR023837 EccCb-like, Actinobacteria AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 Pfam PF01580 FtsK/SpoIIIE family 1109 1195 1.3E-6 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 Pfam PF01580 FtsK/SpoIIIE family 448 569 2.0E-23 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 Pfam PF01580 FtsK/SpoIIIE family 809 1053 1.9E-50 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 SUPERFAMILY SSF52540 436 698 1.0E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 699 8.1E-261 T 12-10-2018 IPR023836 EccCa-like, Actinobacteria AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 Gene3D G3DSA:3.40.50.300 1087 1322 1.3E-57 T 12-10-2018 AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 SUPERFAMILY SSF52540 790 1014 5.33E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 SMART SM00382 1117 1276 3.0 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 SMART SM00382 476 656 0.011 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 SMART SM00382 829 1010 0.87 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 Gene3D G3DSA:3.40.50.300 205 344 1.9E-6 T 12-10-2018 AFR_41575 57c90c1017d3f31149a52ee9ea268742 1326 Gene3D G3DSA:3.40.50.300 793 1082 2.8E-66 T 12-10-2018 AFR_02195 0772a9ff227708df3b5c938e66a2cd46 373 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 12 372 4.4E-165 T 12-10-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 AFR_02195 0772a9ff227708df3b5c938e66a2cd46 373 Gene3D G3DSA:3.90.1150.10 269 373 7.1E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_02195 0772a9ff227708df3b5c938e66a2cd46 373 SUPERFAMILY SSF53383 14 371 1.64E-72 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_02195 0772a9ff227708df3b5c938e66a2cd46 373 Gene3D G3DSA:3.40.640.10 31 267 2.6E-48 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_02195 0772a9ff227708df3b5c938e66a2cd46 373 PIRSF PIRSF000525 5 373 6.8E-70 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFR_02195 0772a9ff227708df3b5c938e66a2cd46 373 Pfam PF00266 Aminotransferase class-V 143 333 1.3E-14 T 12-10-2018 IPR000192 Aminotransferase class V domain AFR_40685 005f5a4a40bc29a0a651c0c668266064 353 SUPERFAMILY SSF101790 282 337 3.27E-5 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal AFR_40685 005f5a4a40bc29a0a651c0c668266064 353 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 263 337 7.7E-10 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AFR_40685 005f5a4a40bc29a0a651c0c668266064 353 SUPERFAMILY SSF103025 18 279 1.13E-50 T 12-10-2018 AFR_40685 005f5a4a40bc29a0a651c0c668266064 353 Pfam PF01571 Aminomethyltransferase folate-binding domain 17 252 5.1E-27 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain AFR_40685 005f5a4a40bc29a0a651c0c668266064 353 Gene3D G3DSA:3.30.1360.120 16 350 9.4E-63 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AFR_40685 005f5a4a40bc29a0a651c0c668266064 353 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 225 289 1.4E-19 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site AFR_40685 005f5a4a40bc29a0a651c0c668266064 353 PIRSF PIRSF006487 10 347 8.9E-19 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFR_04305 54e558cacd692ceffc833ef3fa419c73 425 SUPERFAMILY SSF51261 301 390 3.35E-13 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_04305 54e558cacd692ceffc833ef3fa419c73 425 SUPERFAMILY SSF101898 20 252 2.04E-6 T 12-10-2018 AFR_04305 54e558cacd692ceffc833ef3fa419c73 425 Gene3D G3DSA:2.70.70.10 276 410 4.0E-19 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_04305 54e558cacd692ceffc833ef3fa419c73 425 Pfam PF01551 Peptidase family M23 302 391 1.2E-13 T 12-10-2018 IPR016047 Peptidase M23 AFR_08875 0d9451e4c888362e4b2fde7b0e523adb 198 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 22 151 8.5E-13 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFR_08875 0d9451e4c888362e4b2fde7b0e523adb 198 SMART SM00943 4 162 1.1E-5 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFR_11310 c164f000883c26b507aff371d5f424bb 249 Gene3D G3DSA:3.40.190.10 37 235 6.3E-46 T 12-10-2018 AFR_11310 c164f000883c26b507aff371d5f424bb 249 SUPERFAMILY SSF53850 36 245 1.09E-27 T 12-10-2018 AFR_11310 c164f000883c26b507aff371d5f424bb 249 Pfam PF03466 LysR substrate binding domain 35 239 1.5E-25 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_11310 c164f000883c26b507aff371d5f424bb 249 Gene3D G3DSA:3.40.190.10 108 217 6.3E-46 T 12-10-2018 AFR_31475 2d479c5c40bea7809d2f617cda4ff745 431 Pfam PF07730 Histidine kinase 241 307 6.3E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_31475 2d479c5c40bea7809d2f617cda4ff745 431 SUPERFAMILY SSF55874 314 428 2.56E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31475 2d479c5c40bea7809d2f617cda4ff745 431 Pfam PF13796 Putative sensor 72 216 3.9E-16 T 12-10-2018 IPR025828 Putative sensor domain AFR_31475 2d479c5c40bea7809d2f617cda4ff745 431 Gene3D G3DSA:3.30.565.10 310 429 2.9E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33065 ab9e9a314854b26787df61ad086245db 339 SUPERFAMILY SSF55347 131 273 1.08E-26 T 12-10-2018 AFR_33065 ab9e9a314854b26787df61ad086245db 339 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 208 3.4E-8 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_33065 ab9e9a314854b26787df61ad086245db 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 122 1.2E-19 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_33065 ab9e9a314854b26787df61ad086245db 339 SUPERFAMILY SSF51735 5 157 1.17E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_33065 ab9e9a314854b26787df61ad086245db 339 Gene3D G3DSA:3.30.360.10 124 331 6.2E-103 T 12-10-2018 AFR_33065 ab9e9a314854b26787df61ad086245db 339 Gene3D G3DSA:3.40.50.720 5 309 6.2E-103 T 12-10-2018 AFR_42250 1f41a681f674177aface52bb489f7be7 364 SUPERFAMILY SSF47203 204 356 4.35E-15 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_42250 1f41a681f674177aface52bb489f7be7 364 SUPERFAMILY SSF56645 5 196 1.07E-28 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_42250 1f41a681f674177aface52bb489f7be7 364 Gene3D G3DSA:1.10.540.10 2 103 1.2E-24 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_42250 1f41a681f674177aface52bb489f7be7 364 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 85 1.3E-7 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_42250 1f41a681f674177aface52bb489f7be7 364 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 219 342 1.5E-26 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFR_42250 1f41a681f674177aface52bb489f7be7 364 Gene3D G3DSA:2.40.110.10 107 196 3.9E-30 T 12-10-2018 AFR_42250 1f41a681f674177aface52bb489f7be7 364 PIRSF PIRSF016578 2 362 8.2E-94 T 12-10-2018 AFR_42250 1f41a681f674177aface52bb489f7be7 364 Gene3D G3DSA:1.20.140.10 198 362 3.1E-33 T 12-10-2018 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.7E-96 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 6.5E-237 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 Gene3D G3DSA:1.10.560.10 7 519 7.4E-222 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFR_04920 c58e2b8586cac872230227d05b3f1192 548 Gene3D G3DSA:3.50.7.10 190 370 7.4E-222 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily AFR_04920 c58e2b8586cac872230227d05b3f1192 548 SUPERFAMILY SSF48592 9 519 3.82E-74 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFR_04920 c58e2b8586cac872230227d05b3f1192 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 SUPERFAMILY SSF54849 136 199 2.52E-23 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFR_04920 c58e2b8586cac872230227d05b3f1192 548 PRINTS PR00298 60kDa chaperonin signature 82 109 4.3E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 PRINTS PR00298 60kDa chaperonin signature 348 373 4.3E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 PRINTS PR00298 60kDa chaperonin signature 26 52 4.3E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 PRINTS PR00298 60kDa chaperonin signature 266 289 4.3E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 PRINTS PR00298 60kDa chaperonin signature 396 417 4.3E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 Hamap MF_00600 60 kDa chaperonin [groL]. 1 548 39.884 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_04920 c58e2b8586cac872230227d05b3f1192 548 Gene3D G3DSA:3.30.260.10 135 408 7.4E-222 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFR_04920 c58e2b8586cac872230227d05b3f1192 548 SUPERFAMILY SSF52029 182 374 1.92E-76 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 Gene3D G3DSA:3.40.50.12740 2 142 2.1E-33 T 12-10-2018 AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 SMART SM00448 2 117 3.8E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 SUPERFAMILY SSF52738 195 384 5.75E-66 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 Pfam PF01339 CheB methylesterase 201 379 1.0E-59 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 Pfam PF00072 Response regulator receiver domain 4 117 2.7E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 Gene3D G3DSA:3.40.50.180 193 390 2.4E-70 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 PIRSF PIRSF000876 1 387 4.8E-122 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 SUPERFAMILY SSF52172 1 122 8.4E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_40580 b546a6246b0ba629dc37e7b6abd87e22 397 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 384 37.528 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00283 732 947 1.6E-32 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Pfam PF08447 PAS fold 163 248 1.9E-12 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Pfam PF08447 PAS fold 407 492 1.9E-10 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Pfam PF08447 PAS fold 284 370 2.7E-16 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Pfam PF08447 PAS fold 529 614 2.0E-15 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Pfam PF08447 PAS fold 651 736 9.8E-11 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Gene3D G3DSA:1.10.287.950 737 941 3.9E-51 T 12-10-2018 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Gene3D G3DSA:3.30.450.20 638 736 2.5E-21 T 12-10-2018 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Pfam PF08448 PAS fold 33 134 2.1E-7 T 12-10-2018 IPR013656 PAS fold-4 AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00091 140 208 2.2 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00091 504 574 3.4 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00091 384 452 3.0 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00091 628 696 0.0041 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00091 262 329 2.0 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00091 15 81 6.9 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 Gene3D G3DSA:3.30.450.20 515 637 5.4E-22 T 12-10-2018 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Gene3D G3DSA:3.30.450.20 389 514 1.3E-21 T 12-10-2018 AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00086 579 621 4.4E-4 T 12-10-2018 IPR001610 PAC motif AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00086 335 377 8.5E-6 T 12-10-2018 IPR001610 PAC motif AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00086 213 255 3.0E-4 T 12-10-2018 IPR001610 PAC motif AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00086 701 743 5.7 T 12-10-2018 IPR001610 PAC motif AFR_40300 122e5639dc6e846536335376e752ec5e 947 SMART SM00086 457 499 0.02 T 12-10-2018 IPR001610 PAC motif AFR_40300 122e5639dc6e846536335376e752ec5e 947 SUPERFAMILY SSF55785 637 740 5.17E-24 T 12-10-2018 IPR035965 PAS domain superfamily AFR_40300 122e5639dc6e846536335376e752ec5e 947 SUPERFAMILY SSF55785 396 496 2.79E-24 T 12-10-2018 IPR035965 PAS domain superfamily AFR_40300 122e5639dc6e846536335376e752ec5e 947 SUPERFAMILY SSF55785 273 374 8.03E-27 T 12-10-2018 IPR035965 PAS domain superfamily AFR_40300 122e5639dc6e846536335376e752ec5e 947 Gene3D G3DSA:3.30.450.20 26 144 7.1E-10 T 12-10-2018 AFR_40300 122e5639dc6e846536335376e752ec5e 947 SUPERFAMILY SSF55785 517 618 3.14E-26 T 12-10-2018 IPR035965 PAS domain superfamily AFR_40300 122e5639dc6e846536335376e752ec5e 947 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 896 925 2.1E-14 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_40300 122e5639dc6e846536335376e752ec5e 947 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 848 877 2.1E-14 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_40300 122e5639dc6e846536335376e752ec5e 947 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 749 778 2.1E-14 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_40300 122e5639dc6e846536335376e752ec5e 947 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 395 501 9.8E-17 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 636 748 1.8E-16 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 147 257 6.5E-15 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 273 378 4.1E-18 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 517 624 5.9E-18 T 12-10-2018 IPR000014 PAS domain AFR_40300 122e5639dc6e846536335376e752ec5e 947 SUPERFAMILY SSF58104 738 932 1.83E-50 T 12-10-2018 AFR_40300 122e5639dc6e846536335376e752ec5e 947 SUPERFAMILY SSF55785 151 252 6.11E-24 T 12-10-2018 IPR035965 PAS domain superfamily AFR_40300 122e5639dc6e846536335376e752ec5e 947 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 780 930 8.7E-39 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_40300 122e5639dc6e846536335376e752ec5e 947 SUPERFAMILY SSF55785 28 132 1.1E-7 T 12-10-2018 IPR035965 PAS domain superfamily AFR_40300 122e5639dc6e846536335376e752ec5e 947 Gene3D G3DSA:3.30.450.20 145 269 6.2E-22 T 12-10-2018 AFR_40300 122e5639dc6e846536335376e752ec5e 947 Gene3D G3DSA:3.30.450.20 270 387 2.1E-23 T 12-10-2018 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 SUPERFAMILY SSF52096 295 554 1.8E-33 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_05285 e78964c8d93661e1625ba406a841fd80 597 Pfam PF00378 Enoyl-CoA hydratase/isomerase 317 486 1.1E-18 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 Gene3D G3DSA:3.90.226.10 293 552 6.0E-31 T 12-10-2018 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 SUPERFAMILY SSF50486 178 257 4.32E-14 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 SUPERFAMILY SSF53328 4 161 4.97E-23 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 PIRSF PIRSF006787 1 575 1.0E-199 T 12-10-2018 IPR009188 [NiFe]-hydrogenase maturation factor, HypX/HoxX type AFR_05285 e78964c8d93661e1625ba406a841fd80 597 Gene3D G3DSA:3.40.50.170 19 167 4.8E-17 T 12-10-2018 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 Gene3D G3DSA:3.10.25.10 179 265 1.6E-8 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 Pfam PF02911 Formyl transferase, C-terminal domain 177 259 3.0E-13 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_05285 e78964c8d93661e1625ba406a841fd80 597 Pfam PF00551 Formyl transferase 36 123 1.3E-5 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_11860 12b7820fefc50eb97026e6090b5e0233 259 Pfam PF12706 Beta-lactamase superfamily domain 17 220 2.8E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_11860 12b7820fefc50eb97026e6090b5e0233 259 Gene3D G3DSA:3.60.15.10 1 253 9.5E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_11860 12b7820fefc50eb97026e6090b5e0233 259 SUPERFAMILY SSF56281 1 231 5.69E-17 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_32050 232e7206941c41e284ae9a950bb81710 950 Gene3D G3DSA:3.40.50.300 4 169 3.2E-7 T 12-10-2018 AFR_32050 232e7206941c41e284ae9a950bb81710 950 Pfam PF00196 Bacterial regulatory proteins, luxR family 891 945 1.1E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32050 232e7206941c41e284ae9a950bb81710 950 SMART SM00421 889 946 4.6E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32050 232e7206941c41e284ae9a950bb81710 950 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 35 48 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFR_32050 232e7206941c41e284ae9a950bb81710 950 Gene3D G3DSA:1.25.40.10 330 509 7.6E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32050 232e7206941c41e284ae9a950bb81710 950 SUPERFAMILY SSF52540 6 237 6.46E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32050 232e7206941c41e284ae9a950bb81710 950 Pfam PF13191 AAA ATPase domain 9 155 8.4E-24 T 12-10-2018 AFR_32050 232e7206941c41e284ae9a950bb81710 950 SUPERFAMILY SSF48452 401 509 1.02E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32050 232e7206941c41e284ae9a950bb81710 950 Gene3D G3DSA:1.10.10.10 873 948 6.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32050 232e7206941c41e284ae9a950bb81710 950 ProSitePatterns PS00622 LuxR-type HTH domain signature. 906 933 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32050 232e7206941c41e284ae9a950bb81710 950 SUPERFAMILY SSF46894 882 948 1.6E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_32050 232e7206941c41e284ae9a950bb81710 950 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 906 922 2.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32050 232e7206941c41e284ae9a950bb81710 950 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 892 906 2.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32050 232e7206941c41e284ae9a950bb81710 950 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 922 934 2.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32050 232e7206941c41e284ae9a950bb81710 950 SUPERFAMILY SSF48452 478 669 8.85E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 Gene3D G3DSA:3.60.40.10 381 601 6.9E-53 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 Pfam PF01590 GAF domain 207 359 2.1E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 Pfam PF01590 GAF domain 34 169 1.4E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 SUPERFAMILY SSF55781 34 175 1.79E-23 T 12-10-2018 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 SMART SM00065 33 179 1.5E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 SMART SM00065 207 369 3.3E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 SUPERFAMILY SSF81606 403 601 9.68E-6 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 415 601 4.4E-37 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 SUPERFAMILY SSF55781 190 376 6.11E-16 T 12-10-2018 AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 Gene3D G3DSA:3.30.450.40 22 182 4.6E-19 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 Gene3D G3DSA:3.30.450.40 183 373 1.4E-21 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_06100 01a3f981a04b2d6fc8ddcd6c4a3e02ac 602 SMART SM00331 386 601 4.5E-26 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 SUPERFAMILY SSF88659 180 265 4.49E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 Pfam PF04539 Sigma-70 region 3 128 197 3.1E-14 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 SUPERFAMILY SSF88946 36 116 4.84E-29 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 Pfam PF04545 Sigma-70, region 4 212 260 1.4E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 PIRSF PIRSF000770 41 145 5.6E-17 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 PIRSF PIRSF000770 133 267 2.8E-15 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 Gene3D G3DSA:1.10.10.10 119 170 2.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 Gene3D G3DSA:1.10.601.10 2 118 1.5E-20 T 12-10-2018 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 PRINTS PR00046 Major sigma-70 factor signature 216 228 2.1E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 PRINTS PR00046 Major sigma-70 factor signature 248 259 2.1E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 PRINTS PR00046 Major sigma-70 factor signature 233 248 2.1E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 PRINTS PR00046 Major sigma-70 factor signature 71 84 2.1E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 42 263 2.0E-86 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 SUPERFAMILY SSF88659 120 194 4.8E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 Pfam PF04542 Sigma-70 region 2 48 116 3.7E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 263 1.3E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_03105 b7547c07a35c00896362fd5efca8d85f 268 Gene3D G3DSA:1.10.10.10 194 266 2.6E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_18345 81056df4bdf84eb9ef0a67a4a76207b1 312 Gene3D G3DSA:3.30.750.44 11 250 2.2E-88 T 12-10-2018 AFR_18345 81056df4bdf84eb9ef0a67a4a76207b1 312 SMART SM00245 69 275 5.8E-22 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFR_18345 81056df4bdf84eb9ef0a67a4a76207b1 312 Pfam PF03572 Peptidase family S41 105 274 1.8E-23 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFR_18345 81056df4bdf84eb9ef0a67a4a76207b1 312 SUPERFAMILY SSF52096 41 288 1.44E-51 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_18345 81056df4bdf84eb9ef0a67a4a76207b1 312 Gene3D G3DSA:3.90.226.10 73 283 2.2E-88 T 12-10-2018 AFR_18345 81056df4bdf84eb9ef0a67a4a76207b1 312 Pfam PF11918 N-terminal domain of Peptidase_S41 in eukaryotic IRBP 2 79 4.0E-7 T 12-10-2018 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 127 140 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Pfam PF04539 Sigma-70 region 3 182 250 4.9E-17 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Pfam PF00140 Sigma-70 factor, region 1.2 41 74 4.6E-12 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 SUPERFAMILY SSF88946 38 173 1.23E-52 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Gene3D G3DSA:1.10.10.10 254 337 1.1E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 PRINTS PR00046 Major sigma-70 factor signature 127 140 1.4E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 PRINTS PR00046 Major sigma-70 factor signature 151 159 1.4E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 PRINTS PR00046 Major sigma-70 factor signature 297 312 1.4E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 PRINTS PR00046 Major sigma-70 factor signature 276 288 1.4E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 PRINTS PR00046 Major sigma-70 factor signature 312 323 1.4E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Gene3D G3DSA:1.10.601.10 86 175 2.0E-52 T 12-10-2018 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 SUPERFAMILY SSF88659 235 331 2.24E-21 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 SUPERFAMILY SSF88659 176 247 1.96E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 297 323 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Gene3D G3DSA:1.10.10.10 176 250 1.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Pfam PF04542 Sigma-70 region 2 103 172 7.1E-23 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Gene3D G3DSA:1.20.120.1810 38 85 1.8E-6 T 12-10-2018 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 Pfam PF04545 Sigma-70, region 4 272 325 3.7E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_35415 a50fc124baec3ad9055f05e491f0ccc4 337 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 99 325 4.0E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_26820 aeb93d790fc6daf990fb0174453e4214 93 Pfam PF09360 Iron-binding zinc finger CDGSH type 14 59 3.0E-18 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 AFR_26820 aeb93d790fc6daf990fb0174453e4214 93 SMART SM00704 26 64 9.7E-10 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 AFR_26820 aeb93d790fc6daf990fb0174453e4214 93 Gene3D G3DSA:3.40.5.90 6 70 1.5E-15 T 12-10-2018 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 125 5.3E-28 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 SUPERFAMILY SSF53738 270 374 5.49E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 3.8E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 215 228 3.8E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 244 259 3.8E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 3.8E-22 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 SUPERFAMILY SSF55957 378 458 1.2E-17 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Gene3D G3DSA:3.40.120.10 261 378 5.1E-36 T 12-10-2018 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Gene3D G3DSA:3.40.120.10 178 260 2.3E-32 T 12-10-2018 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Gene3D G3DSA:3.30.310.50 379 459 6.2E-21 T 12-10-2018 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 264 7.0E-25 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 383 457 1.6E-15 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Gene3D G3DSA:3.40.120.10 5 144 6.5E-38 T 12-10-2018 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 SUPERFAMILY SSF53738 159 266 5.1E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 270 378 6.8E-23 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_05715 82c5718d5c00cec370ccb6a78c78ac29 459 SUPERFAMILY SSF53738 7 171 3.83E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_37615 f444b87f50e4bee82a90271668f0a97c 379 Pfam PF00144 Beta-lactamase 3 363 2.4E-56 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_37615 f444b87f50e4bee82a90271668f0a97c 379 Gene3D G3DSA:3.40.710.10 1 367 1.4E-99 T 12-10-2018 AFR_37615 f444b87f50e4bee82a90271668f0a97c 379 SUPERFAMILY SSF56601 3 361 1.5E-76 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 193 203 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 Gene3D G3DSA:3.30.70.80 42 121 1.7E-20 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 Gene3D G3DSA:3.40.50.200 124 398 5.8E-88 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 Pfam PF00082 Subtilase family 160 379 1.0E-33 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 Pfam PF05922 Peptidase inhibitor I9 51 122 6.7E-9 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 SUPERFAMILY SSF54897 50 122 3.23E-13 T 12-10-2018 AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 189 202 3.8E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 153 172 3.8E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 3.8E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 SUPERFAMILY SSF52743 125 392 6.15E-75 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_10200 ce871353121a0b7fd92b9ee29055768b 399 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 158 169 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 SUPERFAMILY SSF141868 500 748 2.09E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 SMART SM00267 310 484 9.2E-54 T 12-10-2018 IPR000160 GGDEF domain AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 Gene3D G3DSA:3.30.450.40 146 321 9.3E-26 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 Gene3D G3DSA:3.30.70.270 322 495 2.1E-57 T 12-10-2018 AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 Pfam PF13185 GAF domain 173 311 5.3E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 Gene3D G3DSA:3.20.20.450 496 751 4.3E-101 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 SUPERFAMILY SSF55781 141 311 4.36E-22 T 12-10-2018 AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 322 483 2.4E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 SUPERFAMILY SSF55073 328 486 2.67E-48 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 Pfam PF00563 EAL domain 500 737 2.0E-76 T 12-10-2018 IPR001633 EAL domain AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 SMART SM00052 494 742 2.9E-114 T 12-10-2018 IPR001633 EAL domain AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 SMART SM00065 172 321 1.4E-13 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_02855 f49db3b97c5c4bd16d8946f4dde81975 757 Pfam PF00990 Diguanylate cyclase, GGDEF domain 323 480 1.4E-46 T 12-10-2018 IPR000160 GGDEF domain AFR_41865 ffcb446c2a77a249b908ab939a27dacb 102 Pfam PF00462 Glutaredoxin 28 85 2.1E-11 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFR_41865 ffcb446c2a77a249b908ab939a27dacb 102 Gene3D G3DSA:3.40.30.10 24 102 1.0E-14 T 12-10-2018 AFR_41865 ffcb446c2a77a249b908ab939a27dacb 102 SUPERFAMILY SSF52833 28 99 7.61E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_35660 9348e9875ed6be096f99017db1914591 66 Pfam PF11248 Protein of unknown function (DUF3046) 1 63 3.9E-21 T 12-10-2018 IPR021408 Protein of unknown function DUF3046 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Gene3D G3DSA:3.90.640.10 204 282 1.4E-97 T 12-10-2018 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 SUPERFAMILY SSF53067 7 158 9.71E-29 T 12-10-2018 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 PRINTS PR00301 70kDa heat shock protein signature 338 358 9.4E-14 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 PRINTS PR00301 70kDa heat shock protein signature 5 18 9.4E-14 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 PRINTS PR00301 70kDa heat shock protein signature 307 323 9.4E-14 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 PRINTS PR00301 70kDa heat shock protein signature 177 187 9.4E-14 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Gene3D G3DSA:3.30.420.40 162 340 1.4E-97 T 12-10-2018 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 SUPERFAMILY SSF53067 166 352 7.24E-39 T 12-10-2018 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Gene3D G3DSA:3.30.420.40 7 349 1.4E-97 T 12-10-2018 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 SUPERFAMILY SSF82171 805 1043 1.27E-30 T 12-10-2018 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Pfam PF00012 Hsp70 protein 7 77 1.5E-4 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Pfam PF00012 Hsp70 protein 85 357 4.7E-41 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Gene3D G3DSA:2.120.10.30 900 1043 3.1E-33 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Gene3D G3DSA:2.120.10.30 759 899 9.2E-20 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Pfam PF07676 WD40-like Beta Propeller Repeat 986 1009 0.13 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Pfam PF07676 WD40-like Beta Propeller Repeat 938 963 1.9E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 Pfam PF07676 WD40-like Beta Propeller Repeat 860 883 0.0092 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_25845 57788d378d06a1a9310ddca4bcdee0f2 1043 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFR_12940 78ef103765ff075710d6030403bb58b9 225 SUPERFAMILY SSF46894 138 218 3.74E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_12940 78ef103765ff075710d6030403bb58b9 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 8.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12940 78ef103765ff075710d6030403bb58b9 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 8.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12940 78ef103765ff075710d6030403bb58b9 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 8.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12940 78ef103765ff075710d6030403bb58b9 225 SMART SM00421 155 212 2.1E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12940 78ef103765ff075710d6030403bb58b9 225 SUPERFAMILY SSF52172 1 136 1.71E-24 T 12-10-2018 IPR011006 CheY-like superfamily AFR_12940 78ef103765ff075710d6030403bb58b9 225 Gene3D G3DSA:3.40.50.12740 2 218 5.9E-56 T 12-10-2018 AFR_12940 78ef103765ff075710d6030403bb58b9 225 Pfam PF00072 Response regulator receiver domain 5 118 2.1E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_12940 78ef103765ff075710d6030403bb58b9 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 3.1E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12940 78ef103765ff075710d6030403bb58b9 225 SMART SM00448 2 118 7.5E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_42980 858ccf5d8b43818b3359889d21967ac7 191 Gene3D G3DSA:3.30.1370.50 127 191 2.7E-21 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 AFR_42980 858ccf5d8b43818b3359889d21967ac7 191 SUPERFAMILY SSF82708 145 189 5.3E-8 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 AFR_42980 858ccf5d8b43818b3359889d21967ac7 191 Pfam PF01424 R3H domain 131 189 3.2E-14 T 12-10-2018 IPR001374 R3H domain GO:0003676 AFR_42980 858ccf5d8b43818b3359889d21967ac7 191 SMART SM00393 111 190 9.7E-20 T 12-10-2018 IPR001374 R3H domain GO:0003676 AFR_42980 858ccf5d8b43818b3359889d21967ac7 191 Gene3D G3DSA:3.30.300.20 44 126 1.7E-12 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_01405 a5f3f5d031ce01ce12f9b6ec3ad0a3f8 298 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 13 297 1.2E-94 T 12-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related AFR_01405 a5f3f5d031ce01ce12f9b6ec3ad0a3f8 298 Gene3D G3DSA:1.20.120.1780 175 298 7.1E-38 T 12-10-2018 AFR_01405 a5f3f5d031ce01ce12f9b6ec3ad0a3f8 298 Gene3D G3DSA:1.10.357.140 20 173 1.1E-51 T 12-10-2018 AFR_01405 a5f3f5d031ce01ce12f9b6ec3ad0a3f8 298 Pfam PF01040 UbiA prenyltransferase family 45 279 4.9E-51 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 Gene3D G3DSA:2.40.110.10 133 244 7.6E-41 T 12-10-2018 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 Gene3D G3DSA:1.10.540.10 12 132 2.4E-37 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 348 367 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 229 3.1E-24 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 SUPERFAMILY SSF47203 241 387 1.77E-38 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 SUPERFAMILY SSF56645 11 251 9.03E-77 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 129 1.9E-29 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 Gene3D G3DSA:1.20.140.10 245 389 3.3E-36 T 12-10-2018 AFR_28375 cd4b30d6e371c964c30b9448f614c21b 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 387 1.9E-36 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_32000 087e5418b3ce9ea9a4d79cbfa223112c 147 Pfam PF12802 MarR family 48 91 6.5E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32000 087e5418b3ce9ea9a4d79cbfa223112c 147 SUPERFAMILY SSF46785 8 138 3.19E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_32000 087e5418b3ce9ea9a4d79cbfa223112c 147 Gene3D G3DSA:1.10.10.10 3 139 2.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32000 087e5418b3ce9ea9a4d79cbfa223112c 147 SMART SM00347 28 127 1.9E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 Gene3D G3DSA:3.40.50.720 8 240 2.8E-57 T 12-10-2018 AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 SUPERFAMILY SSF51735 6 238 8.17E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.5E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.5E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.5E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.5E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 2.5E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 4.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 4.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 212 0.0037 T 12-10-2018 AFR_23040 3dde4c90669bce786a5b47143ee31cb3 241 Pfam PF00106 short chain dehydrogenase 13 197 7.4E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_01560 9f6491457414160dcb9a2b2f77aa81d4 688 Gene3D G3DSA:3.40.50.300 412 502 2.7E-6 T 12-10-2018 AFR_01560 9f6491457414160dcb9a2b2f77aa81d4 688 Gene3D G3DSA:3.40.50.300 516 675 7.4E-15 T 12-10-2018 AFR_01560 9f6491457414160dcb9a2b2f77aa81d4 688 Gene3D G3DSA:3.40.50.300 166 291 3.5E-9 T 12-10-2018 AFR_01560 9f6491457414160dcb9a2b2f77aa81d4 688 SUPERFAMILY SSF52540 168 667 1.31E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01560 9f6491457414160dcb9a2b2f77aa81d4 688 Pfam PF13245 AAA domain 181 486 7.6E-7 T 12-10-2018 AFR_18025 d30d9fe7904aeb9f37c05653a36068b9 170 Gene3D G3DSA:3.40.50.880 21 170 2.1E-29 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_18025 d30d9fe7904aeb9f37c05653a36068b9 170 SUPERFAMILY SSF52317 49 169 2.79E-25 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_18025 d30d9fe7904aeb9f37c05653a36068b9 170 Pfam PF01965 DJ-1/PfpI family 70 155 8.0E-8 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 Gene3D G3DSA:1.25.40.10 897 1194 2.5E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 Gene3D G3DSA:1.25.40.10 709 896 1.5E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 SUPERFAMILY SSF48452 721 813 1.98E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 Gene3D G3DSA:3.30.70.1230 24 217 4.5E-53 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 SUPERFAMILY SSF48452 784 939 5.69E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 29 201 3.6E-23 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 SUPERFAMILY SSF52540 225 513 1.83E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 SUPERFAMILY SSF55073 27 209 3.77E-48 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 SMART SM00044 18 189 2.9E-6 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 SUPERFAMILY SSF48452 948 1084 9.01E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41630 84b96f01b1032f4717afadd4f64cb2b5 1210 Pfam PF13191 AAA ATPase domain 225 438 4.4E-15 T 12-10-2018 AFR_01335 0d0983341f7a9379590f126f12639701 276 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 23 53 1.4E-8 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFR_01335 0d0983341f7a9379590f126f12639701 276 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 81 253 6.5E-37 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 SUPERFAMILY SSF48029 119 331 1.05E-59 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 Pfam PF01706 FliG C-terminal domain 223 330 3.2E-39 T 12-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 SUPERFAMILY SSF48029 9 119 1.6E-18 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 Gene3D G3DSA:1.10.220.30 109 196 1.5E-27 T 12-10-2018 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 Gene3D G3DSA:1.10.220.30 201 340 5.3E-45 T 12-10-2018 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PIRSF PIRSF003161 6 340 5.8E-105 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 Pfam PF14842 FliG N-terminal domain 11 112 5.3E-28 T 12-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 Gene3D G3DSA:1.10.220.30 5 88 1.5E-16 T 12-10-2018 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 Pfam PF14841 FliG middle domain 120 193 3.4E-26 T 12-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PRINTS PR00954 Flagellar motor switch protein FliG signature 232 252 1.6E-65 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PRINTS PR00954 Flagellar motor switch protein FliG signature 11 27 1.6E-65 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PRINTS PR00954 Flagellar motor switch protein FliG signature 201 226 1.6E-65 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PRINTS PR00954 Flagellar motor switch protein FliG signature 278 304 1.6E-65 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PRINTS PR00954 Flagellar motor switch protein FliG signature 40 66 1.6E-65 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PRINTS PR00954 Flagellar motor switch protein FliG signature 254 274 1.6E-65 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 1.6E-65 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_40440 80a4836b929a75f9c1fea9d94c55f0b5 341 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 10 338 1.5E-106 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 SMART SM00347 31 135 1.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 Pfam PF12802 MarR family 38 98 4.9E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 Gene3D G3DSA:1.10.10.10 6 152 1.6E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 2.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23120 349b11670bf1b0aeb7b0937331b01c39 156 SUPERFAMILY SSF46785 3 150 5.91E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_08870 d1bb6dbb255da088b0f713f6d0cbef8c 168 Gene3D G3DSA:3.40.630.30 1 168 5.1E-34 T 12-10-2018 AFR_08870 d1bb6dbb255da088b0f713f6d0cbef8c 168 SUPERFAMILY SSF55729 8 164 7.09E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_08870 d1bb6dbb255da088b0f713f6d0cbef8c 168 Pfam PF00583 Acetyltransferase (GNAT) family 72 148 5.3E-15 T 12-10-2018 IPR000182 GNAT domain AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 SUPERFAMILY SSF55816 1094 1297 2.62E-44 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 SUPERFAMILY SSF49299 1402 1476 7.06E-7 T 12-10-2018 IPR035986 PKD domain superfamily AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Gene3D G3DSA:2.60.40.10 1311 1402 6.4E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Gene3D G3DSA:2.60.40.10 1403 1484 1.2E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Gene3D G3DSA:3.90.780.10 1106 1300 1.1E-52 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Pfam PF02872 5'-nucleotidase, C-terminal domain 1097 1263 1.1E-37 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 SMART SM00089 1315 1401 0.68 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 SMART SM00089 1403 1482 0.22 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Pfam PF00149 Calcineurin-like phosphoesterase 793 1018 5.6E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 PRINTS PR01607 Apyrase family signature 788 806 1.2E-22 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 PRINTS PR01607 Apyrase family signature 967 984 1.2E-22 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 PRINTS PR01607 Apyrase family signature 1000 1023 1.2E-22 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 PRINTS PR01607 Apyrase family signature 1161 1184 1.2E-22 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 PRINTS PR01607 Apyrase family signature 1032 1052 1.2E-22 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 PRINTS PR01607 Apyrase family signature 1238 1257 1.2E-22 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 SUPERFAMILY SSF49299 1303 1390 4.19E-7 T 12-10-2018 IPR035986 PKD domain superfamily AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 SUPERFAMILY SSF56219 476 777 3.17E-30 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Gene3D G3DSA:3.60.21.10 786 1093 1.2E-67 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 SUPERFAMILY SSF56300 785 1090 4.83E-62 T 12-10-2018 AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 481 773 3.0E-9 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_42125 bd34902f47fc37aeb5123b4882e4249c 1607 Gene3D G3DSA:3.60.10.10 478 780 9.6E-41 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_09225 65e6d9942b0ac9c068bff67ac35d9ef8 307 SUPERFAMILY SSF102114 39 305 6.67E-58 T 12-10-2018 AFR_09225 65e6d9942b0ac9c068bff67ac35d9ef8 307 Pfam PF04055 Radical SAM superfamily 81 235 7.4E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_09225 65e6d9942b0ac9c068bff67ac35d9ef8 307 PIRSF PIRSF005963 4 307 2.0E-120 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFR_09225 65e6d9942b0ac9c068bff67ac35d9ef8 307 Gene3D G3DSA:3.20.20.70 75 280 3.1E-13 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_09225 65e6d9942b0ac9c068bff67ac35d9ef8 307 SMART SM00729 71 277 2.9E-11 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_09225 65e6d9942b0ac9c068bff67ac35d9ef8 307 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 138.184 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFR_09225 65e6d9942b0ac9c068bff67ac35d9ef8 307 TIGRFAM TIGR00510 lipA: lipoyl synthase 19 302 4.8E-95 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFR_13655 a328c5c0a94e92c7c1d22857e4f95131 350 SUPERFAMILY SSF51679 11 344 2.49E-71 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_13655 a328c5c0a94e92c7c1d22857e4f95131 350 Pfam PF00296 Luciferase-like monooxygenase 25 307 9.1E-46 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_13655 a328c5c0a94e92c7c1d22857e4f95131 350 Gene3D G3DSA:3.20.20.30 2 348 1.6E-78 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_13655 a328c5c0a94e92c7c1d22857e4f95131 350 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 10 343 7.1E-150 T 12-10-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative AFR_32295 752e48fe0fdae30b51a61191eefeda74 381 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 331 1.4E-10 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_32295 752e48fe0fdae30b51a61191eefeda74 381 Gene3D G3DSA:3.40.50.300 179 331 7.9E-15 T 12-10-2018 AFR_32295 752e48fe0fdae30b51a61191eefeda74 381 SUPERFAMILY SSF52540 198 337 2.67E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32295 752e48fe0fdae30b51a61191eefeda74 381 SMART SM00382 198 334 9.1E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01050 ae4bea54eed9d3ef74e19d118f0de87c 182 Pfam PF11188 Protein of unknown function (DUF2975) 39 182 1.3E-12 T 12-10-2018 IPR021354 Protein of unknown function DUF2975 AFR_11295 2d4e40a00f519eedd21d509c44a09df0 165 Pfam PF08044 Domain of unknown function (DUF1707) 25 77 1.1E-21 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 Gene3D G3DSA:3.30.450.40 130 293 5.9E-13 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 SUPERFAMILY SSF81606 327 530 3.14E-6 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 Gene3D G3DSA:3.30.565.10 537 661 1.9E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 SUPERFAMILY SSF55874 573 657 8.43E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 Pfam PF13581 Histidine kinase-like ATPase domain 545 655 1.8E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 SUPERFAMILY SSF55781 145 293 1.47E-11 T 12-10-2018 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 Gene3D G3DSA:3.30.450.20 5 129 5.2E-14 T 12-10-2018 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 SMART SM00065 143 293 0.0017 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 341 532 1.2E-43 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 Pfam PF08448 PAS fold 12 125 3.6E-5 T 12-10-2018 IPR013656 PAS fold-4 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 SUPERFAMILY SSF55785 10 117 3.24E-6 T 12-10-2018 IPR035965 PAS domain superfamily AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 SMART SM00331 319 532 9.1E-39 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31380 c043699aecb20f0bd7e6f284378763d3 663 Gene3D G3DSA:3.60.40.10 307 533 1.9E-56 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 157 1.9E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 161 1.0E-52 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 Gene3D G3DSA:1.10.10.10 77 164 1.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 Pfam PF08281 Sigma-70, region 4 103 155 1.3E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 SUPERFAMILY SSF88946 6 92 4.71E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 SUPERFAMILY SSF88659 97 159 1.63E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 Pfam PF04542 Sigma-70 region 2 18 77 1.2E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_42890 150fb7f050232c1e3d89bf199495b6d2 173 Gene3D G3DSA:1.10.1740.10 2 76 1.1E-10 T 12-10-2018 AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 184 2.8E-4 T 12-10-2018 AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 Gene3D G3DSA:3.40.50.720 1 245 7.7E-78 T 12-10-2018 AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 7.8E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 7.8E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.8E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 7.8E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.8E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 SUPERFAMILY SSF51735 5 243 3.85E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29475 1ed6d54e0a17adc4a4ec761ef9b7b521 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 243 6.2E-59 T 12-10-2018 AFR_03335 79b7351bf297241ed9035285aea97a83 486 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 266 282 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 SUPERFAMILY SSF52283 11 486 2.38E-112 T 12-10-2018 AFR_03335 79b7351bf297241ed9035285aea97a83 486 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 8 478 48.062 T 12-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 AFR_03335 79b7351bf297241ed9035285aea97a83 486 Gene3D G3DSA:3.40.50.720 247 407 1.4E-235 T 12-10-2018 AFR_03335 79b7351bf297241ed9035285aea97a83 486 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 244 406 4.7E-79 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 12 485 4.3E-145 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 84 98 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 PIRSF PIRSF001109 1 486 2.3E-185 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 SUPERFAMILY SSF51735 244 406 9.87E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03335 79b7351bf297241ed9035285aea97a83 486 SMART SM00997 244 406 3.2E-102 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 SMART SM00996 12 485 0.0 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 13 478 5.9E-186 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFR_03335 79b7351bf297241ed9035285aea97a83 486 Gene3D G3DSA:3.40.50.1480 15 486 1.4E-235 T 12-10-2018 AFR_04570 634246c74f56e889142abd56416055cd 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.48 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z AFR_04570 634246c74f56e889142abd56416055cd 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04570 634246c74f56e889142abd56416055cd 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.9E-24 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04570 634246c74f56e889142abd56416055cd 61 Gene3D G3DSA:4.10.830.10 1 61 2.8E-30 T 12-10-2018 AFR_04570 634246c74f56e889142abd56416055cd 61 SUPERFAMILY SSF57716 4 61 2.78E-21 T 12-10-2018 AFR_14695 391965674cf47a74874844c620959783 81 Gene3D G3DSA:2.40.128.290 1 71 4.5E-35 T 12-10-2018 IPR038646 Atu4866-like superfamily AFR_14695 391965674cf47a74874844c620959783 81 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 1 69 8.1E-35 T 12-10-2018 IPR020955 Uncharacterised protein family Atu4866 AFR_36405 86e11dc3ff60942f604bf574aedb99ea 835 Gene3D G3DSA:3.90.550.10 171 431 8.2E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_36405 86e11dc3ff60942f604bf574aedb99ea 835 Pfam PF00535 Glycosyl transferase family 2 212 325 1.7E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_36405 86e11dc3ff60942f604bf574aedb99ea 835 SUPERFAMILY SSF53448 211 422 1.83E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_36405 86e11dc3ff60942f604bf574aedb99ea 835 SUPERFAMILY SSF53756 710 812 1.18E-6 T 12-10-2018 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Pfam PF01556 DnaJ C terminal domain 122 336 8.3E-37 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Gene3D G3DSA:1.10.287.110 1 110 2.8E-33 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Pfam PF00684 DnaJ central domain 146 210 4.1E-12 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 SUPERFAMILY SSF57938 133 213 4.71E-17 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 SMART SM00271 3 60 1.7E-31 T 12-10-2018 IPR001623 DnaJ domain AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Gene3D G3DSA:2.60.260.20 257 364 1.2E-27 T 12-10-2018 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Pfam PF00226 DnaJ domain 4 65 2.4E-26 T 12-10-2018 IPR001623 DnaJ domain AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 SUPERFAMILY SSF49493 112 265 5.76E-17 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 374 36.97 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 SUPERFAMILY SSF46565 3 100 1.57E-32 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Gene3D G3DSA:2.10.230.10 146 210 7.4E-33 T 12-10-2018 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 353 7.1E-116 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 Gene3D G3DSA:2.60.260.20 116 252 7.4E-33 T 12-10-2018 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 SUPERFAMILY SSF49493 262 347 6.93E-20 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 PRINTS PR00625 DnaJ domain signature 40 60 4.2E-25 T 12-10-2018 IPR001623 DnaJ domain AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 PRINTS PR00625 DnaJ domain signature 6 24 4.2E-25 T 12-10-2018 IPR001623 DnaJ domain AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 PRINTS PR00625 DnaJ domain signature 60 79 4.2E-25 T 12-10-2018 IPR001623 DnaJ domain AFR_07845 abf0652cb6101bcb33d08ab47faa37fc 378 PRINTS PR00625 DnaJ domain signature 24 39 4.2E-25 T 12-10-2018 IPR001623 DnaJ domain AFR_11645 27bc77d07cd868524dfcceed055611ce 313 Gene3D G3DSA:3.40.50.720 1 274 1.2E-36 T 12-10-2018 AFR_11645 27bc77d07cd868524dfcceed055611ce 313 SUPERFAMILY SSF51735 1 297 1.04E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11645 27bc77d07cd868524dfcceed055611ce 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 226 5.2E-14 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_01065 b04b867b37ce823059a3dd037a2269bf 333 SUPERFAMILY SSF48452 45 180 1.03E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_01065 b04b867b37ce823059a3dd037a2269bf 333 Gene3D G3DSA:3.10.450.50 286 329 6.4E-6 T 12-10-2018 AFR_01065 b04b867b37ce823059a3dd037a2269bf 333 Pfam PF02810 SEC-C motif 311 329 1.9E-6 T 12-10-2018 IPR004027 SEC-C motif AFR_01065 b04b867b37ce823059a3dd037a2269bf 333 SUPERFAMILY SSF103642 310 328 9.32E-6 T 12-10-2018 AFR_12575 684d6149b82fd234d38c8e9cb79b8d6d 456 SUPERFAMILY SSF53720 4 454 4.06E-127 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_12575 684d6149b82fd234d38c8e9cb79b8d6d 456 Pfam PF00171 Aldehyde dehydrogenase family 3 451 1.8E-130 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_12575 684d6149b82fd234d38c8e9cb79b8d6d 456 Gene3D G3DSA:3.40.309.10 231 420 3.0E-132 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_12575 684d6149b82fd234d38c8e9cb79b8d6d 456 Gene3D G3DSA:3.40.605.10 3 442 3.0E-132 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 9 156 2.7E-37 T 12-10-2018 IPR023635 Peptide deformylase AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 Hamap MF_00163 Peptide deformylase [def]. 2 160 28.351 T 12-10-2018 IPR023635 Peptide deformylase AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 Gene3D G3DSA:3.90.45.10 1 177 6.1E-53 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 Pfam PF01327 Polypeptide deformylase 4 148 5.4E-41 T 12-10-2018 IPR023635 Peptide deformylase AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 PIRSF PIRSF004749 1 174 8.1E-44 T 12-10-2018 IPR023635 Peptide deformylase AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 SUPERFAMILY SSF56420 3 164 2.75E-52 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 PRINTS PR01576 Peptide deformylase signature 33 62 2.1E-31 T 12-10-2018 IPR023635 Peptide deformylase AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 PRINTS PR01576 Peptide deformylase signature 118 147 2.1E-31 T 12-10-2018 IPR023635 Peptide deformylase AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 PRINTS PR01576 Peptide deformylase signature 99 117 2.1E-31 T 12-10-2018 IPR023635 Peptide deformylase AFR_30555 93363ca0dad6f584f2ee3624330cbd2a 185 PRINTS PR01576 Peptide deformylase signature 87 98 2.1E-31 T 12-10-2018 IPR023635 Peptide deformylase AFR_27175 307403577c806d70a693820be150ef2a 395 Pfam PF05762 VWA domain containing CoxE-like protein 165 375 4.2E-50 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like AFR_27175 307403577c806d70a693820be150ef2a 395 SMART SM00327 215 377 3.1E-4 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_27175 307403577c806d70a693820be150ef2a 395 Gene3D G3DSA:3.40.50.410 210 359 4.9E-6 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_27175 307403577c806d70a693820be150ef2a 395 PIRSF PIRSF010256 5 387 2.7E-84 T 12-10-2018 IPR011195 Uncharacterised conserved protein UCP010256 AFR_27175 307403577c806d70a693820be150ef2a 395 SUPERFAMILY SSF53300 214 344 4.23E-11 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_10760 c202da9c5c55c4b06541efe35ef3ccf6 256 Pfam PF13560 Helix-turn-helix domain 2 45 3.3E-8 T 12-10-2018 AFR_11920 8f6c830cde15f433db1538c6770c117b 296 Gene3D G3DSA:3.40.190.10 94 282 3.1E-28 T 12-10-2018 AFR_11920 8f6c830cde15f433db1538c6770c117b 296 Gene3D G3DSA:1.10.10.10 1 90 6.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11920 8f6c830cde15f433db1538c6770c117b 296 Pfam PF03466 LysR substrate binding domain 92 291 2.2E-28 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_11920 8f6c830cde15f433db1538c6770c117b 296 SUPERFAMILY SSF46785 2 110 2.07E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11920 8f6c830cde15f433db1538c6770c117b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11920 8f6c830cde15f433db1538c6770c117b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11920 8f6c830cde15f433db1538c6770c117b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11920 8f6c830cde15f433db1538c6770c117b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11920 8f6c830cde15f433db1538c6770c117b 296 Gene3D G3DSA:3.40.190.10 162 270 3.1E-28 T 12-10-2018 AFR_11920 8f6c830cde15f433db1538c6770c117b 296 SUPERFAMILY SSF53850 92 292 1.5E-26 T 12-10-2018 AFR_10105 e4450b722400609e670084074e20e9c2 436 Gene3D G3DSA:3.40.50.1980 239 356 6.6E-108 T 12-10-2018 AFR_10105 e4450b722400609e670084074e20e9c2 436 SUPERFAMILY SSF53720 24 434 1.96E-67 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_10105 e4450b722400609e670084074e20e9c2 436 Pfam PF00815 Histidinol dehydrogenase 19 434 6.3E-154 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 Gene3D G3DSA:3.40.50.1980 30 237 6.6E-108 T 12-10-2018 AFR_10105 e4450b722400609e670084074e20e9c2 436 PIRSF PIRSF000099 7 436 6.8E-150 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 PRINTS PR00083 Histidinol dehydrogenase signature 133 159 3.7E-72 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 PRINTS PR00083 Histidinol dehydrogenase signature 206 231 3.7E-72 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 PRINTS PR00083 Histidinol dehydrogenase signature 368 386 3.7E-72 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 PRINTS PR00083 Histidinol dehydrogenase signature 235 256 3.7E-72 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 PRINTS PR00083 Histidinol dehydrogenase signature 327 352 3.7E-72 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 PRINTS PR00083 Histidinol dehydrogenase signature 257 276 3.7E-72 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 PRINTS PR00083 Histidinol dehydrogenase signature 32 56 3.7E-72 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 433 2.5E-139 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 235 267 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 AFR_10105 e4450b722400609e670084074e20e9c2 436 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 434 38.391 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 SUPERFAMILY SSF51445 301 635 1.54E-86 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 Gene3D G3DSA:2.70.98.60 1 286 1.3E-28 T 12-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 22 263 1.4E-41 T 12-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PIRSF PIRSF005536 2 667 4.5E-157 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 ProSitePatterns PS00512 Alpha-galactosidase signature. 334 350 - T 12-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 Gene3D G3DSA:3.20.20.70 287 604 8.9E-116 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 624 704 1.9E-7 T 12-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 441 456 9.1E-38 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 220 235 9.1E-38 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 492 508 9.1E-38 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 383 405 9.1E-38 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 517 533 9.1E-38 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 305 319 9.1E-38 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 333 348 9.1E-38 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_18415 a18bd4b1c61ca4dbe42d36889f64f12e 721 Pfam PF02065 Melibiase 268 605 1.1E-112 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_31010 9224f4da1ba87fbde30a16badf191be3 177 SUPERFAMILY SSF46689 3 73 3.64E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_31010 9224f4da1ba87fbde30a16badf191be3 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 57 8.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_31010 9224f4da1ba87fbde30a16badf191be3 177 SUPERFAMILY SSF48498 77 177 3.72E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_31010 9224f4da1ba87fbde30a16badf191be3 177 Gene3D G3DSA:1.10.357.10 1 177 4.5E-45 T 12-10-2018 AFR_37595 0579226d3e274abd089be730f07b120d 417 SUPERFAMILY SSF47384 167 245 3.92E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_37595 0579226d3e274abd089be730f07b120d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 345 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_37595 0579226d3e274abd089be730f07b120d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 381 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_37595 0579226d3e274abd089be730f07b120d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 359 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_37595 0579226d3e274abd089be730f07b120d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 400 2.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_37595 0579226d3e274abd089be730f07b120d 417 Gene3D G3DSA:1.10.287.130 163 247 2.5E-15 T 12-10-2018 AFR_37595 0579226d3e274abd089be730f07b120d 417 SMART SM00388 179 247 4.5E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_37595 0579226d3e274abd089be730f07b120d 417 Gene3D G3DSA:3.30.565.10 254 407 3.4E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_37595 0579226d3e274abd089be730f07b120d 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 295 401 8.0E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_37595 0579226d3e274abd089be730f07b120d 417 SMART SM00387 294 403 1.3E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_37595 0579226d3e274abd089be730f07b120d 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 245 6.4E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_37595 0579226d3e274abd089be730f07b120d 417 SUPERFAMILY SSF55874 257 400 1.09E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03945 54c14ec79a2506a436d6e496c9e16b75 243 Pfam PF00072 Response regulator receiver domain 20 129 8.1E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_03945 54c14ec79a2506a436d6e496c9e16b75 243 SMART SM00862 165 239 4.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_03945 54c14ec79a2506a436d6e496c9e16b75 243 SUPERFAMILY SSF52172 17 199 4.98E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFR_03945 54c14ec79a2506a436d6e496c9e16b75 243 Gene3D G3DSA:3.40.50.2300 2 143 1.1E-37 T 12-10-2018 AFR_03945 54c14ec79a2506a436d6e496c9e16b75 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 167 239 2.9E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_03945 54c14ec79a2506a436d6e496c9e16b75 243 Gene3D G3DSA:1.10.10.10 144 243 1.2E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03945 54c14ec79a2506a436d6e496c9e16b75 243 SMART SM00448 18 129 3.3E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 SMART SM00382 630 809 5.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 SUPERFAMILY SSF49785 380 551 1.53E-18 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 SUPERFAMILY SSF53474 45 343 4.59E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 Gene3D G3DSA:2.60.120.260 399 549 3.2E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 Gene3D G3DSA:3.40.50.300 595 836 1.2E-56 T 12-10-2018 AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 Pfam PF00005 ABC transporter 622 761 6.0E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 429 540 3.1E-14 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 SMART SM00939 331 548 8.5E-7 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 SUPERFAMILY SSF52540 605 823 9.48E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 ProSitePatterns PS00211 ABC transporters family signature. 734 748 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_40935 25ccf1943a58c53ea0fcd4bb4d765fec 907 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 45 285 4.3E-20 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 SUPERFAMILY SSF49384 273 377 5.79E-34 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 SMART SM00637 277 376 1.1E-48 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 Gene3D G3DSA:2.60.120.180 31 263 2.5E-86 T 12-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 SUPERFAMILY SSF49899 32 251 6.11E-73 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 323 336 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 Gene3D G3DSA:2.60.40.290 272 378 1.7E-36 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 Pfam PF01670 Glycosyl hydrolase family 12 46 251 4.0E-62 T 12-10-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 AFR_34770 0ae7f0906143f99b1e850dd1c90ec662 379 Pfam PF00553 Cellulose binding domain 277 376 8.1E-32 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 SUPERFAMILY SSF56507 903 1207 1.27E-102 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 SMART SM01018 650 733 4.2E-44 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 TIGRFAM TIGR02082 metH: methionine synthase 20 1173 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Gene3D G3DSA:3.10.196.10 905 1202 5.3E-111 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 PIRSF PIRSF000381 8 1176 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 937 1189 4.7E-95 T 12-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Gene3D G3DSA:1.10.288.10 935 1076 5.3E-111 T 12-10-2018 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Pfam PF02310 B12 binding domain 750 843 1.9E-18 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Pfam PF02574 Homocysteine S-methyltransferase 23 321 9.1E-76 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Gene3D G3DSA:3.20.20.330 8 336 7.8E-124 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Gene3D G3DSA:1.10.1240.10 643 730 2.7E-38 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Gene3D G3DSA:3.40.50.280 746 897 1.2E-50 T 12-10-2018 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Pfam PF00809 Pterin binding enzyme 356 594 1.1E-51 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 SUPERFAMILY SSF51717 352 626 4.06E-82 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 SUPERFAMILY SSF82282 13 395 9.42E-114 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Pfam PF02607 B12 binding domain 652 726 4.9E-26 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 SUPERFAMILY SSF47644 645 732 3.27E-28 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 SUPERFAMILY SSF52242 746 896 1.2E-41 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_26565 3f5c89c48f66d03ca8e9efab1dd85009 1212 Gene3D G3DSA:3.20.20.20 337 638 4.0E-124 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_42635 d59c9be2516fa877f74b60db2b724e61 193 Gene3D G3DSA:3.90.550.10 1 193 1.4E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_42635 d59c9be2516fa877f74b60db2b724e61 193 Pfam PF12804 MobA-like NTP transferase domain 1 147 1.3E-23 T 12-10-2018 IPR025877 MobA-like NTP transferase AFR_42635 d59c9be2516fa877f74b60db2b724e61 193 SUPERFAMILY SSF53448 1 185 8.56E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16150 fbc2eea86770805c00f7966562f89391 379 Gene3D G3DSA:3.30.565.10 254 376 1.1E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_16150 fbc2eea86770805c00f7966562f89391 379 Pfam PF07730 Histidine kinase 182 247 3.2E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_16150 fbc2eea86770805c00f7966562f89391 379 SUPERFAMILY SSF55874 287 376 4.22E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_16150 fbc2eea86770805c00f7966562f89391 379 SMART SM00387 287 377 1.8E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_16150 fbc2eea86770805c00f7966562f89391 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 355 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_16150 fbc2eea86770805c00f7966562f89391 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 374 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_16150 fbc2eea86770805c00f7966562f89391 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 336 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31425 92156361aad9418faee4e2a1562e5961 228 SUPERFAMILY SSF81301 5 88 6.08E-9 T 12-10-2018 AFR_31425 92156361aad9418faee4e2a1562e5961 228 Gene3D G3DSA:3.30.460.10 4 91 1.6E-6 T 12-10-2018 AFR_31425 92156361aad9418faee4e2a1562e5961 228 Pfam PF01909 Nucleotidyltransferase domain 17 49 3.3E-6 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 Hamap MF_00384 Homoserine kinase [thrB]. 12 293 28.837 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 PIRSF PIRSF000676 6 283 3.1E-79 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 SUPERFAMILY SSF54211 10 155 1.67E-32 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 Pfam PF00288 GHMP kinases N terminal domain 87 147 3.1E-10 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 TIGRFAM TIGR00191 thrB: homoserine kinase 10 266 1.0E-63 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 SUPERFAMILY SSF55060 171 267 9.11E-22 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 93 104 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 PRINTS PR00958 Homoserine kinase signature 17 32 5.9E-35 T 12-10-2018 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 PRINTS PR00958 Homoserine kinase signature 134 147 5.9E-35 T 12-10-2018 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 PRINTS PR00958 Homoserine kinase signature 250 265 5.9E-35 T 12-10-2018 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 PRINTS PR00958 Homoserine kinase signature 173 190 5.9E-35 T 12-10-2018 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 PRINTS PR00958 Homoserine kinase signature 100 115 5.9E-35 T 12-10-2018 AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 Pfam PF08544 GHMP kinases C terminal 226 266 1.0E-4 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 Gene3D G3DSA:3.30.230.10 12 165 2.8E-81 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_37455 0f5b6bef400ddc13db506c3de001f635 311 Gene3D G3DSA:3.30.70.890 166 266 2.8E-81 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.8E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 Pfam PF00027 Cyclic nucleotide-binding domain 29 111 6.6E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 12-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 SUPERFAMILY SSF51206 4 142 8.12E-38 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 Gene3D G3DSA:2.60.120.10 1 146 2.5E-48 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 SMART SM00419 167 215 2.8E-11 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 SUPERFAMILY SSF46785 145 223 1.87E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 SMART SM00100 10 128 1.5E-26 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_41610 76091d326cbae792c939d5e5a93ba4fb 225 Gene3D G3DSA:1.10.10.10 147 224 7.1E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17840 28e96010291de90967e6d6d216356ee3 236 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 158 173 6.3E-7 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_17840 28e96010291de90967e6d6d216356ee3 236 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 78 93 6.3E-7 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_17840 28e96010291de90967e6d6d216356ee3 236 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 66 210 4.5E-25 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_17840 28e96010291de90967e6d6d216356ee3 236 Gene3D G3DSA:2.40.100.10 61 225 4.2E-39 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_17840 28e96010291de90967e6d6d216356ee3 236 SUPERFAMILY SSF50891 65 212 4.38E-33 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 SUPERFAMILY SSF56645 8 212 8.77E-42 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 SUPERFAMILY SSF47203 231 368 3.7E-19 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 PIRSF PIRSF016578 117 371 1.6E-25 T 12-10-2018 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 PIRSF PIRSF016578 1 106 1.0E-7 T 12-10-2018 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 Gene3D G3DSA:2.40.110.10 125 217 2.1E-24 T 12-10-2018 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 Gene3D G3DSA:1.10.540.10 1 100 1.3E-18 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 234 354 2.4E-14 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 113 203 1.1E-12 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 76 9.2E-8 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_22275 78d25b91e6e41a43940672ad4e34484a 371 Gene3D G3DSA:1.20.140.10 218 371 3.1E-21 T 12-10-2018 AFR_38080 cab14724eb525f393e3867ea20e00874 564 Gene3D G3DSA:3.90.480.20 33 404 3.2E-121 T 12-10-2018 AFR_38080 cab14724eb525f393e3867ea20e00874 564 SUPERFAMILY SSF56014 418 563 5.63E-34 T 12-10-2018 AFR_38080 cab14724eb525f393e3867ea20e00874 564 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 466 482 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 SUPERFAMILY SSF56014 171 323 1.96E-42 T 12-10-2018 AFR_38080 cab14724eb525f393e3867ea20e00874 564 SUPERFAMILY SSF55124 20 170 4.58E-40 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 Gene3D G3DSA:3.30.413.10 163 339 3.2E-121 T 12-10-2018 AFR_38080 cab14724eb525f393e3867ea20e00874 564 SUPERFAMILY SSF55124 337 412 1.44E-18 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 PRINTS PR00397 Sirohaem Fe-binding site signature 466 484 1.4E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 PRINTS PR00397 Sirohaem Fe-binding site signature 421 439 1.4E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 97 161 1.7E-18 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 344 408 3.0E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 421 542 2.2E-8 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_38080 cab14724eb525f393e3867ea20e00874 564 Gene3D G3DSA:3.30.413.10 417 564 1.2E-37 T 12-10-2018 AFR_38080 cab14724eb525f393e3867ea20e00874 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 171 322 3.5E-34 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 Hamap MF_00318 Enolase [eno]. 2 409 45.09 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 1.6E-202 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 ProSitePatterns PS00164 Enolase signature. 332 345 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 SMART SM01192 139 423 2.8E-215 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 PIRSF PIRSF001400 1 422 1.9E-189 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 Pfam PF03952 Enolase, N-terminal domain 4 134 3.2E-58 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 SMART SM01193 4 134 2.7E-89 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 419 6.4E-129 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 SUPERFAMILY SSF54826 3 138 8.84E-55 T 12-10-2018 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 SUPERFAMILY SSF51604 138 422 7.99E-128 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 PRINTS PR00148 Enolase signature 161 174 3.1E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 PRINTS PR00148 Enolase signature 332 346 3.1E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 PRINTS PR00148 Enolase signature 37 51 3.1E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 PRINTS PR00148 Enolase signature 107 123 3.1E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 PRINTS PR00148 Enolase signature 361 378 3.1E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 PRINTS PR00148 Enolase signature 309 320 3.1E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 Gene3D G3DSA:3.30.390.10 1 126 2.6E-54 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFR_05325 d6aed05a6dc3c786518d0326869a0c67 427 Gene3D G3DSA:3.20.20.120 128 424 3.6E-133 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 253 9.1E-46 T 12-10-2018 AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 SUPERFAMILY SSF51735 12 253 9.13E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 Gene3D G3DSA:3.40.50.720 7 256 2.8E-69 T 12-10-2018 AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 4.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 182 6.6E-4 T 12-10-2018 AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20490 6d5190f6aaa538b11eaa113b8c2a22b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04910 2b1c2848572ccaf99c8329329911a688 388 SUPERFAMILY SSF53335 71 225 6.15E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_04910 2b1c2848572ccaf99c8329329911a688 388 Gene3D G3DSA:3.40.50.150 83 249 5.9E-36 T 12-10-2018 AFR_04910 2b1c2848572ccaf99c8329329911a688 388 Pfam PF08241 Methyltransferase domain 103 168 1.8E-8 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_02715 26c91e3eea3d3c0d70ae74690e8eb639 394 SUPERFAMILY SSF53720 74 254 9.82E-8 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_02715 26c91e3eea3d3c0d70ae74690e8eb639 394 Pfam PF05893 Acyl-CoA reductase (LuxC) 75 270 1.5E-30 T 12-10-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 AFR_21610 83127832fb6ef72d3f370ec98694116b 237 SUPERFAMILY SSF46955 13 113 5.95E-10 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_21610 83127832fb6ef72d3f370ec98694116b 237 Pfam PF13411 MerR HTH family regulatory protein 127 190 1.9E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21610 83127832fb6ef72d3f370ec98694116b 237 Pfam PF00376 MerR family regulatory protein 14 47 6.0E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21610 83127832fb6ef72d3f370ec98694116b 237 SMART SM00422 9 79 0.022 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21610 83127832fb6ef72d3f370ec98694116b 237 SMART SM00422 125 192 7.8E-4 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21610 83127832fb6ef72d3f370ec98694116b 237 Gene3D G3DSA:1.10.1660.10 3 116 5.2E-10 T 12-10-2018 AFR_21610 83127832fb6ef72d3f370ec98694116b 237 Gene3D G3DSA:1.10.1660.10 124 236 2.8E-15 T 12-10-2018 AFR_21610 83127832fb6ef72d3f370ec98694116b 237 SUPERFAMILY SSF46955 125 231 7.33E-14 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 Gene3D G3DSA:2.40.110.10 132 269 6.5E-47 T 12-10-2018 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 Gene3D G3DSA:1.20.140.10 495 626 6.5E-24 T 12-10-2018 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 46 128 3.4E-5 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 SUPERFAMILY SSF47203 272 447 2.79E-46 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 Gene3D G3DSA:1.20.140.10 276 446 7.9E-50 T 12-10-2018 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 Pfam PF01756 Acyl-CoA oxidase 497 636 3.2E-23 T 12-10-2018 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 242 8.0E-14 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 276 437 6.6E-10 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 SUPERFAMILY SSF56645 24 259 1.07E-46 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 SUPERFAMILY SSF47203 492 636 7.01E-37 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_23290 787bcfa1b54a544f23118f56d61f7731 663 PIRSF PIRSF000168 6 661 3.6E-164 T 12-10-2018 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0071949 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858|Reactome: R-HSA-9033241 AFR_36715 27ba91f946d7a69b98d2fe0b097a2179 262 Gene3D G3DSA:1.10.10.60 11 88 1.3E-23 T 12-10-2018 AFR_36715 27ba91f946d7a69b98d2fe0b097a2179 262 SUPERFAMILY SSF46689 27 89 2.64E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_36715 27ba91f946d7a69b98d2fe0b097a2179 262 SUPERFAMILY SSF48498 104 251 4.23E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_36715 27ba91f946d7a69b98d2fe0b097a2179 262 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 101 249 2.8E-11 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_36715 27ba91f946d7a69b98d2fe0b097a2179 262 Gene3D G3DSA:1.10.357.10 93 250 3.2E-31 T 12-10-2018 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PIRSF PIRSF001112 1 378 2.6E-96 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_23540 16ce00ce558deb11d899daea501224ae 396 Pfam PF06441 Epoxide hydrolase N terminus 6 105 5.3E-22 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_23540 16ce00ce558deb11d899daea501224ae 396 SUPERFAMILY SSF53474 5 374 3.31E-91 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 141 6.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00111 Alpha/beta hydrolase fold signature 171 184 6.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00111 Alpha/beta hydrolase fold signature 185 198 6.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00412 Epoxide hydrolase signature 126 141 1.4E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00412 Epoxide hydrolase signature 349 371 1.4E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00412 Epoxide hydrolase signature 97 115 1.4E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00412 Epoxide hydrolase signature 185 198 1.4E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23540 16ce00ce558deb11d899daea501224ae 396 PRINTS PR00412 Epoxide hydrolase signature 318 334 1.4E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23540 16ce00ce558deb11d899daea501224ae 396 Gene3D G3DSA:3.40.50.1820 6 380 2.4E-122 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20945 90aa1b9c92d397d0642ebf70d944d5cc 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 256 2.6E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_20945 90aa1b9c92d397d0642ebf70d944d5cc 264 Gene3D G3DSA:1.10.3720.10 12 263 9.2E-30 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20945 90aa1b9c92d397d0642ebf70d944d5cc 264 SUPERFAMILY SSF161098 11 254 6.82E-32 T 12-10-2018 IPR035906 MetI-like superfamily AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 PIRSF PIRSF002888 2 311 4.8E-83 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 SUPERFAMILY SSF101801 235 307 3.4E-10 T 12-10-2018 IPR036429 SpoA-like superfamily AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 PRINTS PR00955 Flagellar motor switch protein FliM signature 194 212 2.1E-10 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 PRINTS PR00955 Flagellar motor switch protein FliM signature 74 90 2.1E-10 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 PRINTS PR00955 Flagellar motor switch protein FliM signature 99 118 2.1E-10 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 236 299 3.9E-12 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 Gene3D G3DSA:2.30.330.10 225 301 1.1E-5 T 12-10-2018 IPR036429 SpoA-like superfamily AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 Gene3D G3DSA:3.40.1550.10 29 213 2.5E-51 T 12-10-2018 IPR028976 CheC-like superfamily AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 SUPERFAMILY SSF103039 30 208 1.73E-16 T 12-10-2018 IPR028976 CheC-like superfamily AFR_40500 29e2f843ce53c5a87e02d645b4727d94 311 Pfam PF02154 Flagellar motor switch protein FliM 23 211 5.4E-46 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFR_22700 4c3188cc3500956b5c9cbca3f32a1da8 201 SUPERFAMILY SSF46689 15 83 1.13E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_22700 4c3188cc3500956b5c9cbca3f32a1da8 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 3.5E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22700 4c3188cc3500956b5c9cbca3f32a1da8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 8.2E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22700 4c3188cc3500956b5c9cbca3f32a1da8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 8.2E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22700 4c3188cc3500956b5c9cbca3f32a1da8 201 SUPERFAMILY SSF48498 91 196 2.04E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_22700 4c3188cc3500956b5c9cbca3f32a1da8 201 Gene3D G3DSA:1.10.357.10 16 200 3.4E-40 T 12-10-2018 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 Gene3D G3DSA:1.20.120.1810 5 101 1.2E-21 T 12-10-2018 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 27 249 9.4E-87 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 SUPERFAMILY SSF88946 25 102 1.16E-29 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 249 5.3E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 Pfam PF04545 Sigma-70, region 4 198 246 1.3E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 SUPERFAMILY SSF88659 166 251 7.1E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 Gene3D G3DSA:1.10.10.10 103 156 2.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 PIRSF PIRSF000770 9 130 2.0E-18 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 PIRSF PIRSF000770 119 253 1.5E-15 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 Pfam PF04542 Sigma-70 region 2 34 102 3.3E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 Gene3D G3DSA:1.10.10.10 180 252 3.4E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 Pfam PF04539 Sigma-70 region 3 114 183 2.8E-14 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 PRINTS PR00046 Major sigma-70 factor signature 57 70 1.8E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 PRINTS PR00046 Major sigma-70 factor signature 234 245 1.8E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 PRINTS PR00046 Major sigma-70 factor signature 219 234 1.8E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 PRINTS PR00046 Major sigma-70 factor signature 202 214 1.8E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_27050 eed707ce024e2d1763cf3f609fdb118c 253 SUPERFAMILY SSF88659 106 180 4.32E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_23970 79ef9031f23111aeb60d49ebc0805f64 327 SUPERFAMILY SSF161098 85 312 3.01E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_23970 79ef9031f23111aeb60d49ebc0805f64 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 318 4.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_23970 79ef9031f23111aeb60d49ebc0805f64 327 Gene3D G3DSA:1.10.3720.10 80 325 2.9E-59 T 12-10-2018 IPR035906 MetI-like superfamily AFR_10145 c76823d8edb9798946b7661ee9165985 297 SUPERFAMILY SSF53850 91 295 1.01E-28 T 12-10-2018 AFR_10145 c76823d8edb9798946b7661ee9165985 297 SUPERFAMILY SSF46785 1 112 2.65E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10145 c76823d8edb9798946b7661ee9165985 297 Gene3D G3DSA:3.40.190.10 170 266 2.9E-37 T 12-10-2018 AFR_10145 c76823d8edb9798946b7661ee9165985 297 Gene3D G3DSA:1.10.10.10 1 91 1.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10145 c76823d8edb9798946b7661ee9165985 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.7E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_10145 c76823d8edb9798946b7661ee9165985 297 Pfam PF03466 LysR substrate binding domain 90 292 8.1E-32 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_10145 c76823d8edb9798946b7661ee9165985 297 Gene3D G3DSA:3.40.190.10 92 280 2.9E-37 T 12-10-2018 AFR_29290 2d11b1979def15d13b1defa977acd3b7 223 Pfam PF01965 DJ-1/PfpI family 22 219 1.7E-14 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_29290 2d11b1979def15d13b1defa977acd3b7 223 SUPERFAMILY SSF52317 3 223 7.76E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_29290 2d11b1979def15d13b1defa977acd3b7 223 Gene3D G3DSA:3.40.50.880 1 223 3.2E-68 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_38755 8314cc9a3baaf235d11290c6b721f773 278 SUPERFAMILY SSF51735 5 242 1.48E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38755 8314cc9a3baaf235d11290c6b721f773 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38755 8314cc9a3baaf235d11290c6b721f773 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38755 8314cc9a3baaf235d11290c6b721f773 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38755 8314cc9a3baaf235d11290c6b721f773 278 Pfam PF00106 short chain dehydrogenase 5 201 1.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38755 8314cc9a3baaf235d11290c6b721f773 278 Gene3D G3DSA:3.40.50.720 3 275 6.0E-46 T 12-10-2018 AFR_24650 67af77b2647601b117fefbcc8aad1214 238 Pfam PF14470 Bacterial PH domain 77 166 5.8E-14 T 12-10-2018 IPR039519 YokE-like, PH domain AFR_24650 67af77b2647601b117fefbcc8aad1214 238 Pfam PF09851 Short C-terminal domain 208 235 1.8E-9 T 12-10-2018 IPR018649 SHOCT domain AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 Gene3D G3DSA:2.60.120.10 18 155 3.7E-19 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 SUPERFAMILY SSF51206 21 148 4.84E-21 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 SMART SM00100 30 153 4.3E-12 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 57 73 - T 12-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 Gene3D G3DSA:3.30.565.10 339 490 2.2E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 Gene3D G3DSA:1.10.287.130 156 248 2.8E-7 T 12-10-2018 AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 485 3.2E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 Pfam PF00027 Cyclic nucleotide-binding domain 49 139 7.4E-11 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 444 1.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 484 1.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 1.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 1.4E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 SMART SM00387 379 487 5.2E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_33220 ba9dab5129ee27ec0c914c22e037a80f 491 SUPERFAMILY SSF55874 325 486 2.75E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_14590 a1d5695dada8fd1a0527e269a87eb79b 368 Pfam PF00005 ABC transporter 34 185 2.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_14590 a1d5695dada8fd1a0527e269a87eb79b 368 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 304 1.2E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_14590 a1d5695dada8fd1a0527e269a87eb79b 368 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 325 2.9E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_14590 a1d5695dada8fd1a0527e269a87eb79b 368 SUPERFAMILY SSF52540 5 257 8.57E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14590 a1d5695dada8fd1a0527e269a87eb79b 368 Gene3D G3DSA:3.40.50.300 3 340 2.7E-101 T 12-10-2018 AFR_14590 a1d5695dada8fd1a0527e269a87eb79b 368 SMART SM00382 42 235 2.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_14590 a1d5695dada8fd1a0527e269a87eb79b 368 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_22230 9b8c44dad3b6f54c83031d5231d59a49 357 SUPERFAMILY SSF55031 162 271 1.64E-16 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFR_22230 9b8c44dad3b6f54c83031d5231d59a49 357 Gene3D G3DSA:3.40.630.10 8 340 9.5E-74 T 12-10-2018 AFR_22230 9b8c44dad3b6f54c83031d5231d59a49 357 Pfam PF01546 Peptidase family M20/M25/M40 65 353 3.2E-26 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_22230 9b8c44dad3b6f54c83031d5231d59a49 357 SUPERFAMILY SSF53187 3 353 2.73E-39 T 12-10-2018 AFR_22230 9b8c44dad3b6f54c83031d5231d59a49 357 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 64 73 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFR_22230 9b8c44dad3b6f54c83031d5231d59a49 357 Gene3D G3DSA:3.30.70.360 161 274 9.5E-74 T 12-10-2018 AFR_22230 9b8c44dad3b6f54c83031d5231d59a49 357 Pfam PF07687 Peptidase dimerisation domain 160 245 1.1E-13 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 Gene3D G3DSA:3.40.50.720 3 238 1.4E-44 T 12-10-2018 AFR_13340 f4538b214a51940bd56010cb949e8205 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13340 f4538b214a51940bd56010cb949e8205 247 Pfam PF00106 short chain dehydrogenase 7 182 1.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13340 f4538b214a51940bd56010cb949e8205 247 SUPERFAMILY SSF51735 1 208 1.69E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 PIRSF PIRSF001084 1 644 2.2E-211 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 SUPERFAMILY SSF51445 1 359 2.32E-95 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 Gene3D G3DSA:3.40.50.880 387 588 2.3E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 Pfam PF08533 Beta-galactosidase C-terminal domain 589 644 1.3E-7 T 12-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 Pfam PF02449 Beta-galactosidase 6 378 2.7E-127 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 SUPERFAMILY SSF52317 387 581 1.53E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 Gene3D G3DSA:3.20.20.80 1 383 3.1E-123 T 12-10-2018 AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 Pfam PF08532 Beta-galactosidase trimerisation domain 389 582 3.8E-48 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_17630 26b2e0e21f2289af54c5461d787ba023 644 Gene3D G3DSA:2.60.40.1180 589 644 3.8E-15 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 Pfam PF09269 Domain of unknown function (DUF1967) 356 424 7.6E-28 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 Pfam PF01926 50S ribosome-binding GTPase 161 283 2.0E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 Gene3D G3DSA:2.40.240.60 354 427 1.7E-28 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.5E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 Pfam PF01018 GTP1/OBG 5 157 2.4E-48 T 12-10-2018 IPR006169 GTP1/OBG domain AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 SUPERFAMILY SSF52540 161 330 1.17E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 Gene3D G3DSA:3.40.50.300 160 344 3.5E-50 T 12-10-2018 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 Gene3D G3DSA:2.70.210.12 1 158 3.6E-46 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 161 322 3.7E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 Hamap MF_01454 GTPase Obg [obg]. 3 330 43.87 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 SUPERFAMILY SSF102741 353 426 2.88E-23 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 327 2.7E-122 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 425 5.5E-29 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 AFR_07690 7c5d7612c2fd5ca24070e83b2c878476 504 SUPERFAMILY SSF82051 4 157 7.32E-45 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 Gene3D G3DSA:1.10.1740.10 1 105 3.4E-26 T 12-10-2018 AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 Pfam PF04542 Sigma-70 region 2 36 92 3.4E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 SUPERFAMILY SSF88659 104 181 8.41E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 SUPERFAMILY SSF88946 3 99 6.28E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 77 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 Gene3D G3DSA:1.10.10.10 106 183 8.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 Pfam PF08281 Sigma-70, region 4 125 175 1.3E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_24710 e3f47959f2daac61444eeecccea9ba69 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 179 1.6E-26 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 SUPERFAMILY SSF81593 344 495 7.61E-41 T 12-10-2018 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Pfam PF08335 GlnD PII-uridylyltransferase 350 494 2.1E-38 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Pfam PF08335 GlnD PII-uridylyltransferase 869 1005 5.6E-17 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Gene3D G3DSA:1.20.120.330 343 497 7.6E-45 T 12-10-2018 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Gene3D G3DSA:1.20.120.330 859 1011 3.4E-32 T 12-10-2018 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 164 326 1.3E-31 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 601 847 3.9E-46 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 SUPERFAMILY SSF81301 96 337 7.52E-55 T 12-10-2018 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 SUPERFAMILY SSF81301 572 852 1.93E-61 T 12-10-2018 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 SUPERFAMILY SSF81593 862 1009 2.28E-30 T 12-10-2018 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Gene3D G3DSA:3.30.460.100 609 852 6.9E-56 T 12-10-2018 AFR_09070 8066c47dd3a1c2247782bbdcc689a9c4 1011 Gene3D G3DSA:3.30.460.100 121 331 3.0E-50 T 12-10-2018 AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.5E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.5E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.5E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 SUPERFAMILY SSF51735 1 248 6.59E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 168 0.0056 T 12-10-2018 AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 9.3E-42 T 12-10-2018 AFR_10850 86a9f9944edd8459a6a000af70c1eeaf 251 Gene3D G3DSA:3.40.50.720 2 249 4.5E-55 T 12-10-2018 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 Pfam PF01494 FAD binding domain 8 339 8.1E-50 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 4.0E-27 T 12-10-2018 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 4.0E-27 T 12-10-2018 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 4.0E-27 T 12-10-2018 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 4.0E-27 T 12-10-2018 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 4.0E-27 T 12-10-2018 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 Gene3D G3DSA:3.30.70.2450 181 268 1.9E-71 T 12-10-2018 AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 Gene3D G3DSA:3.50.50.60 11 339 1.9E-71 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_22975 e18e6b4f57c2136cce24d1aecdba02e6 492 SUPERFAMILY SSF51905 9 377 2.52E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_30475 99361a92d1176763449c46b3fd186e86 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 6.1E-52 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFR_30475 99361a92d1176763449c46b3fd186e86 281 Pfam PF01634 ATP phosphoribosyltransferase 49 202 2.7E-41 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFR_30475 99361a92d1176763449c46b3fd186e86 281 SUPERFAMILY SSF54913 209 280 4.11E-22 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFR_30475 99361a92d1176763449c46b3fd186e86 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 193 280 9.4E-30 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFR_30475 99361a92d1176763449c46b3fd186e86 281 Gene3D G3DSA:3.40.190.10 1 91 5.3E-26 T 12-10-2018 AFR_30475 99361a92d1176763449c46b3fd186e86 281 Gene3D G3DSA:3.30.70.120 209 275 7.7E-25 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFR_30475 99361a92d1176763449c46b3fd186e86 281 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 281 31.704 T 12-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 AFR_30475 99361a92d1176763449c46b3fd186e86 281 Gene3D G3DSA:3.40.190.10 92 176 3.6E-26 T 12-10-2018 AFR_30475 99361a92d1176763449c46b3fd186e86 281 Pfam PF08029 HisG, C-terminal domain 206 278 1.5E-25 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFR_30475 99361a92d1176763449c46b3fd186e86 281 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 AFR_30475 99361a92d1176763449c46b3fd186e86 281 SUPERFAMILY SSF53850 1 207 8.99E-58 T 12-10-2018 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 Pfam PF07085 DRTGG domain 209 319 2.1E-23 T 12-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 SUPERFAMILY SSF53659 366 686 2.3E-91 T 12-10-2018 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 SUPERFAMILY SSF75138 204 321 4.71E-20 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 Pfam PF01515 Phosphate acetyl/butaryl transferase 367 683 1.1E-123 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 Gene3D G3DSA:3.40.50.10950 373 686 3.1E-137 T 12-10-2018 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 SUPERFAMILY SSF52540 5 214 9.3E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 PIRSF PIRSF006107 187 688 3.2E-165 T 12-10-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 PIRSF PIRSF006107 1 191 5.8E-8 T 12-10-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 Gene3D G3DSA:3.40.50.10750 506 659 3.1E-137 T 12-10-2018 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 1.1E-120 T 12-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 Gene3D G3DSA:3.40.50.300 3 200 3.8E-10 T 12-10-2018 AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 Gene3D G3DSA:3.40.1390.20 201 342 1.1E-18 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFR_37995 fb9ad0afe93e4933e4929dabd2d1b6a1 688 Pfam PF13500 AAA domain 4 181 8.3E-16 T 12-10-2018 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 SUPERFAMILY SSF56672 4 233 2.13E-73 T 12-10-2018 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Gene3D G3DSA:3.30.1490.100 239 346 1.8E-18 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Hamap MF_01113 DNA polymerase IV [dinB]. 4 351 32.853 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Pfam PF00817 impB/mucB/samB family 11 151 2.6E-44 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Gene3D G3DSA:3.30.70.270 7 162 5.5E-52 T 12-10-2018 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Pfam PF11798 IMS family HHH motif 168 195 6.5E-7 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 344 3.6E-17 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Gene3D G3DSA:2.30.40.20 24 71 5.5E-52 T 12-10-2018 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 Gene3D G3DSA:1.10.150.20 167 235 5.3E-17 T 12-10-2018 AFR_33930 c78ded1c5773ede326f7684da2c25e88 396 SUPERFAMILY SSF100879 241 353 3.14E-19 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_32855 3e1bf0ff78320dde8c542f329274dde3 189 SUPERFAMILY SSF53448 3 185 1.69E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_32855 3e1bf0ff78320dde8c542f329274dde3 189 Gene3D G3DSA:3.90.550.10 2 189 6.8E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_32855 3e1bf0ff78320dde8c542f329274dde3 189 Pfam PF12804 MobA-like NTP transferase domain 5 165 4.2E-32 T 12-10-2018 IPR025877 MobA-like NTP transferase AFR_03425 850a21a386a208bc6a745788ccad2868 304 Pfam PF00005 ABC transporter 18 156 3.4E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03425 850a21a386a208bc6a745788ccad2868 304 SMART SM00382 26 204 7.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03425 850a21a386a208bc6a745788ccad2868 304 SUPERFAMILY SSF52540 2 218 3.14E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03425 850a21a386a208bc6a745788ccad2868 304 Gene3D G3DSA:3.40.50.300 1 228 7.8E-53 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 Gene3D G3DSA:3.40.50.880 5 199 5.6E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 4 517 53.141 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00097 Anthranilate synthase component II signature 78 89 4.2E-7 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00097 Anthranilate synthase component II signature 167 180 4.2E-7 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00097 Anthranilate synthase component II signature 51 60 4.2E-7 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 Pfam PF00958 GMP synthase C terminal domain 424 516 6.9E-38 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 7 194 5.6E-70 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 SUPERFAMILY SSF54810 396 517 4.05E-46 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 Pfam PF00117 Glutamine amidotransferase class-I 9 190 6.7E-38 T 12-10-2018 IPR017926 Glutamine amidotransferase AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 SUPERFAMILY SSF52317 6 227 1.13E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 2.1E-8 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 2.1E-8 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 2.1E-8 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 Gene3D G3DSA:3.30.300.10 397 517 1.1E-50 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 SUPERFAMILY SSF52402 183 437 6.62E-58 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 202 517 3.2E-146 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 Gene3D G3DSA:3.40.50.620 200 396 5.3E-77 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 48 62 4.1E-6 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 7 21 4.1E-6 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 4.1E-6 T 12-10-2018 AFR_04980 a1799d8dfcaa0de0794dbbe54ba2ffe3 517 Pfam PF02540 NAD synthase 213 245 1.7E-6 T 12-10-2018 IPR022310 NAD/GMP synthase AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 139 1.0E-44 T 12-10-2018 AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 SUPERFAMILY SSF52304 2 140 1.44E-52 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 Pfam PF01220 Dehydroquinase class II 3 138 2.4E-51 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 142 59.279 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 PIRSF PIRSF001399 1 142 2.6E-55 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 Gene3D G3DSA:3.40.50.9100 1 142 1.3E-56 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFR_30655 ff8c5bf8b6f2ca4bfdd3fd87b58ccc09 142 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 139 5.5E-54 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFR_08350 ff8e00b95d40fc6fe07df02b0350bec6 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 180 2.8E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_08350 ff8e00b95d40fc6fe07df02b0350bec6 186 SUPERFAMILY SSF88659 109 180 3.74E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_08350 ff8e00b95d40fc6fe07df02b0350bec6 186 SUPERFAMILY SSF88946 4 108 3.66E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_08350 ff8e00b95d40fc6fe07df02b0350bec6 186 Pfam PF04542 Sigma-70 region 2 29 94 3.4E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_08350 ff8e00b95d40fc6fe07df02b0350bec6 186 Gene3D G3DSA:1.10.10.10 99 182 2.8E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08350 ff8e00b95d40fc6fe07df02b0350bec6 186 Gene3D G3DSA:1.10.1740.10 3 94 1.1E-15 T 12-10-2018 AFR_06365 efb20097395d1f8ceb070423c30478df 413 Gene3D G3DSA:3.40.50.2000 181 353 1.7E-50 T 12-10-2018 AFR_06365 efb20097395d1f8ceb070423c30478df 413 Pfam PF13579 Glycosyl transferase 4-like domain 20 178 4.8E-16 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_06365 efb20097395d1f8ceb070423c30478df 413 Pfam PF00534 Glycosyl transferases group 1 201 351 8.3E-25 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_06365 efb20097395d1f8ceb070423c30478df 413 Gene3D G3DSA:3.40.50.2000 16 180 1.7E-50 T 12-10-2018 AFR_06365 efb20097395d1f8ceb070423c30478df 413 SUPERFAMILY SSF53756 9 366 4.32E-60 T 12-10-2018 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 118 1.1E-14 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 217 1.1E-23 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 Gene3D G3DSA:1.10.540.10 3 121 5.6E-21 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 376 3.2E-28 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 SUPERFAMILY SSF47203 231 380 6.93E-40 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 SUPERFAMILY SSF56645 8 229 4.32E-58 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 Gene3D G3DSA:2.40.110.10 123 228 2.2E-31 T 12-10-2018 AFR_27405 a51a7b7792d87020ec6c9464b5024b39 383 Gene3D G3DSA:1.20.140.10 231 382 1.4E-39 T 12-10-2018 AFR_24845 d764da838bd8d0032f35148f5e0eef16 545 Pfam PF05425 Copper resistance protein D 316 413 1.3E-14 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 AFR_24845 d764da838bd8d0032f35148f5e0eef16 545 Pfam PF04234 CopC domain 22 115 1.7E-20 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 AFR_24845 d764da838bd8d0032f35148f5e0eef16 545 Gene3D G3DSA:2.60.40.1220 22 120 6.8E-21 T 12-10-2018 AFR_24845 d764da838bd8d0032f35148f5e0eef16 545 SUPERFAMILY SSF81296 21 116 2.38E-19 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_27555 35c9ec2c1f209de795c25c5aa298d6f9 466 SUPERFAMILY SSF51338 3 68 1.65E-10 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_27555 35c9ec2c1f209de795c25c5aa298d6f9 466 Gene3D G3DSA:2.30.40.10 4 459 3.2E-172 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_27555 35c9ec2c1f209de795c25c5aa298d6f9 466 Gene3D G3DSA:3.20.20.140 54 428 3.2E-172 T 12-10-2018 AFR_27555 35c9ec2c1f209de795c25c5aa298d6f9 466 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 459 8.4E-169 T 12-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 AFR_27555 35c9ec2c1f209de795c25c5aa298d6f9 466 SUPERFAMILY SSF51338 361 459 1.19E-34 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_27555 35c9ec2c1f209de795c25c5aa298d6f9 466 Pfam PF01979 Amidohydrolase family 50 441 1.3E-26 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_27555 35c9ec2c1f209de795c25c5aa298d6f9 466 SUPERFAMILY SSF51556 54 387 5.11E-100 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_39825 d114f858a147f10427e1ca57a52063dd 598 Gene3D G3DSA:2.20.28.20 139 173 5.4E-145 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 Gene3D G3DSA:3.40.50.620 7 397 5.4E-145 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_39825 d114f858a147f10427e1ca57a52063dd 598 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 527 5.9E-146 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 Gene3D G3DSA:1.10.730.10 398 588 2.8E-33 T 12-10-2018 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 SUPERFAMILY SSF47323 407 596 3.18E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 595 38.673 T 12-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 SUPERFAMILY SSF52374 4 401 1.01E-91 T 12-10-2018 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 Pfam PF09334 tRNA synthetases class I (M) 5 414 1.5E-145 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 SUPERFAMILY SSF57770 139 173 6.02E-12 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 PRINTS PR01041 Methionyl-tRNA synthetase signature 296 311 1.2E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 PRINTS PR01041 Methionyl-tRNA synthetase signature 402 413 1.2E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.2E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.2E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 1.2E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFR_39825 d114f858a147f10427e1ca57a52063dd 598 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.2E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFR_27560 2688c4014480b720c16db408c46bb47d 494 Gene3D G3DSA:3.40.605.10 24 455 3.6E-144 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_27560 2688c4014480b720c16db408c46bb47d 494 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_27560 2688c4014480b720c16db408c46bb47d 494 Gene3D G3DSA:3.40.309.10 249 447 3.6E-144 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_27560 2688c4014480b720c16db408c46bb47d 494 SUPERFAMILY SSF53720 2 480 1.57E-142 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_27560 2688c4014480b720c16db408c46bb47d 494 Pfam PF00171 Aldehyde dehydrogenase family 15 474 1.2E-134 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_27560 2688c4014480b720c16db408c46bb47d 494 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 478 7.1E-204 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 AFR_17340 15327fdb1837594e3c197d663c79f801 397 Pfam PF00512 His Kinase A (phospho-acceptor) domain 186 251 2.5E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_17340 15327fdb1837594e3c197d663c79f801 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 355 5.3E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_17340 15327fdb1837594e3c197d663c79f801 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 379 5.3E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_17340 15327fdb1837594e3c197d663c79f801 397 Gene3D G3DSA:3.30.565.10 249 397 4.4E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17340 15327fdb1837594e3c197d663c79f801 397 SUPERFAMILY SSF158472 134 181 1.07E-8 T 12-10-2018 AFR_17340 15327fdb1837594e3c197d663c79f801 397 SMART SM00387 294 397 6.8E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17340 15327fdb1837594e3c197d663c79f801 397 Gene3D G3DSA:1.10.287.130 136 248 6.9E-26 T 12-10-2018 AFR_17340 15327fdb1837594e3c197d663c79f801 397 SMART SM00388 186 252 8.8E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_17340 15327fdb1837594e3c197d663c79f801 397 SUPERFAMILY SSF47384 169 250 1.0E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_17340 15327fdb1837594e3c197d663c79f801 397 SUPERFAMILY SSF55874 258 396 8.51E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17340 15327fdb1837594e3c197d663c79f801 397 SMART SM00304 132 185 9.4E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_17340 15327fdb1837594e3c197d663c79f801 397 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 294 396 7.5E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17340 15327fdb1837594e3c197d663c79f801 397 Pfam PF00672 HAMP domain 133 181 1.1E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 SMART SM00304 182 234 2.7E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 SMART SM00388 235 302 7.2E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 Gene3D G3DSA:1.10.287.130 186 302 2.5E-26 T 12-10-2018 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 SMART SM00387 338 449 3.1E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 SUPERFAMILY SSF47384 218 300 5.3E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 Gene3D G3DSA:3.30.565.10 307 449 1.8E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 300 3.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 4.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 4.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 446 4.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 401 4.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 446 6.4E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 SUPERFAMILY SSF55874 309 446 3.14E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 Pfam PF00672 HAMP domain 182 230 7.8E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_19230 463d03632f578cf16fdbc09a3f2360b0 450 SUPERFAMILY SSF158472 182 230 6.8E-7 T 12-10-2018 AFR_29650 ccc4b899cdacade3ea757ce8466101dd 201 Gene3D G3DSA:3.40.50.1000 11 192 1.3E-46 T 12-10-2018 IPR023214 HAD superfamily AFR_29650 ccc4b899cdacade3ea757ce8466101dd 201 Gene3D G3DSA:1.10.150.240 23 93 1.3E-46 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_29650 ccc4b899cdacade3ea757ce8466101dd 201 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 123 188 5.1E-17 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_29650 ccc4b899cdacade3ea757ce8466101dd 201 SUPERFAMILY SSF56784 10 196 1.32E-48 T 12-10-2018 IPR036412 HAD-like superfamily AFR_29650 ccc4b899cdacade3ea757ce8466101dd 201 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 190 2.2E-24 T 12-10-2018 AFR_26710 76cc130091bbad471513430c4fe2c342 1171 Gene3D G3DSA:3.40.50.300 396 572 1.1E-6 T 12-10-2018 AFR_26710 76cc130091bbad471513430c4fe2c342 1171 Gene3D G3DSA:3.40.50.300 631 918 2.9E-53 T 12-10-2018 AFR_26710 76cc130091bbad471513430c4fe2c342 1171 SUPERFAMILY SSF52540 649 859 6.17E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26710 76cc130091bbad471513430c4fe2c342 1171 Pfam PF01580 FtsK/SpoIIIE family 642 856 6.8E-18 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_17615 f121e0ff0b03f2815245ba452a8b76d8 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 324 3.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_17615 f121e0ff0b03f2815245ba452a8b76d8 341 Gene3D G3DSA:1.10.3720.10 91 336 3.8E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_17615 f121e0ff0b03f2815245ba452a8b76d8 341 SUPERFAMILY SSF161098 95 322 4.97E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_32645 2fb02fa7261b6850320120186c6f6851 527 SUPERFAMILY SSF48452 53 204 4.34E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32645 2fb02fa7261b6850320120186c6f6851 527 Gene3D G3DSA:1.25.40.10 42 249 5.6E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32645 2fb02fa7261b6850320120186c6f6851 527 SMART SM00267 354 526 9.2E-55 T 12-10-2018 IPR000160 GGDEF domain AFR_32645 2fb02fa7261b6850320120186c6f6851 527 SUPERFAMILY SSF55073 370 524 1.18E-42 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_32645 2fb02fa7261b6850320120186c6f6851 527 Gene3D G3DSA:3.30.70.270 353 525 4.2E-52 T 12-10-2018 AFR_32645 2fb02fa7261b6850320120186c6f6851 527 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 522 6.1E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_32645 2fb02fa7261b6850320120186c6f6851 527 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 524 7.4E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_08315 df27c660726568850958a193d47a9e06 466 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 311 5.4E-20 T 12-10-2018 AFR_08315 df27c660726568850958a193d47a9e06 466 SUPERFAMILY SSF51905 10 389 7.96E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_08315 df27c660726568850958a193d47a9e06 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 8.8E-7 T 12-10-2018 AFR_08315 df27c660726568850958a193d47a9e06 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 198 223 8.8E-7 T 12-10-2018 AFR_08315 df27c660726568850958a193d47a9e06 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 308 8.8E-7 T 12-10-2018 AFR_08315 df27c660726568850958a193d47a9e06 466 Gene3D G3DSA:3.50.50.60 4 396 3.3E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_08315 df27c660726568850958a193d47a9e06 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 5.3E-9 T 12-10-2018 AFR_08315 df27c660726568850958a193d47a9e06 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 309 5.3E-9 T 12-10-2018 AFR_08315 df27c660726568850958a193d47a9e06 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 198 216 5.3E-9 T 12-10-2018 AFR_38505 f09bec0948218fcc33773a05aaadfa46 358 SUPERFAMILY SSF53187 13 356 1.13E-40 T 12-10-2018 AFR_38505 f09bec0948218fcc33773a05aaadfa46 358 Pfam PF01546 Peptidase family M20/M25/M40 70 354 3.2E-21 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_38505 f09bec0948218fcc33773a05aaadfa46 358 Gene3D G3DSA:3.40.630.10 20 344 3.6E-94 T 12-10-2018 AFR_38505 f09bec0948218fcc33773a05aaadfa46 358 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 12 355 7.1E-152 T 12-10-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AFR_38505 f09bec0948218fcc33773a05aaadfa46 358 SUPERFAMILY SSF55031 170 272 2.69E-19 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFR_38505 f09bec0948218fcc33773a05aaadfa46 358 Gene3D G3DSA:3.30.70.360 170 278 3.6E-94 T 12-10-2018 AFR_38505 f09bec0948218fcc33773a05aaadfa46 358 Pfam PF07687 Peptidase dimerisation domain 170 266 1.9E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFR_14060 163f7ea741ba6be91e15563c3d7120e7 607 Gene3D G3DSA:3.30.565.10 468 594 1.3E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_14060 163f7ea741ba6be91e15563c3d7120e7 607 Pfam PF07730 Histidine kinase 400 467 1.8E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_14060 163f7ea741ba6be91e15563c3d7120e7 607 SUPERFAMILY SSF55874 488 593 1.37E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_14060 163f7ea741ba6be91e15563c3d7120e7 607 SMART SM00387 507 596 2.7E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24370 2a71a7cd1ec0e7b21893929d6bc569d9 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 1.4E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_24370 2a71a7cd1ec0e7b21893929d6bc569d9 338 Gene3D G3DSA:3.90.180.10 12 332 5.7E-83 T 12-10-2018 AFR_24370 2a71a7cd1ec0e7b21893929d6bc569d9 338 SMART SM00829 10 336 2.5E-18 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_24370 2a71a7cd1ec0e7b21893929d6bc569d9 338 SUPERFAMILY SSF50129 11 141 3.65E-30 T 12-10-2018 IPR011032 GroES-like superfamily AFR_24370 2a71a7cd1ec0e7b21893929d6bc569d9 338 Pfam PF00107 Zinc-binding dehydrogenase 151 250 6.0E-19 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_24370 2a71a7cd1ec0e7b21893929d6bc569d9 338 SUPERFAMILY SSF51735 112 263 3.64E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24370 2a71a7cd1ec0e7b21893929d6bc569d9 338 Gene3D G3DSA:3.40.50.720 123 272 5.7E-83 T 12-10-2018 AFR_40260 825554fa4c5b221741c490f72d24836e 175 SUPERFAMILY SSF46689 2 69 2.69E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_40260 825554fa4c5b221741c490f72d24836e 175 Gene3D G3DSA:1.10.357.10 1 175 3.9E-45 T 12-10-2018 AFR_40260 825554fa4c5b221741c490f72d24836e 175 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 45 7.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_40260 825554fa4c5b221741c490f72d24836e 175 SUPERFAMILY SSF48498 66 174 2.82E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_42335 3deb2ee045a7c9c6a601853acd493dc8 231 SUPERFAMILY SSF52518 29 226 5.89E-46 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_42335 3deb2ee045a7c9c6a601853acd493dc8 231 Gene3D G3DSA:3.40.50.970 8 231 2.4E-48 T 12-10-2018 AFR_42335 3deb2ee045a7c9c6a601853acd493dc8 231 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 29 223 5.5E-25 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_27600 08c0e47181e74690578c27df115d21b9 692 SUPERFAMILY SSF49299 493 582 1.83E-18 T 12-10-2018 IPR035986 PKD domain superfamily AFR_27600 08c0e47181e74690578c27df115d21b9 692 Gene3D G3DSA:2.60.40.10 491 584 8.5E-21 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27600 08c0e47181e74690578c27df115d21b9 692 Pfam PF07995 Glucose / Sorbosone dehydrogenase 50 331 8.2E-29 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_27600 08c0e47181e74690578c27df115d21b9 692 Gene3D G3DSA:2.120.10.30 24 418 2.0E-65 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_27600 08c0e47181e74690578c27df115d21b9 692 SMART SM00089 502 587 6.2E-18 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_27600 08c0e47181e74690578c27df115d21b9 692 SUPERFAMILY SSF50952 33 480 1.18E-19 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_27600 08c0e47181e74690578c27df115d21b9 692 Pfam PF00801 PKD domain 505 574 3.5E-9 T 12-10-2018 IPR000601 PKD domain AFR_03315 6ddc99c4b3448e008f9a33fd6aa4b1dd 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03315 6ddc99c4b3448e008f9a33fd6aa4b1dd 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03315 6ddc99c4b3448e008f9a33fd6aa4b1dd 206 SUPERFAMILY SSF46689 7 73 3.69E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03315 6ddc99c4b3448e008f9a33fd6aa4b1dd 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 53 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_03315 6ddc99c4b3448e008f9a33fd6aa4b1dd 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 5.9E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03315 6ddc99c4b3448e008f9a33fd6aa4b1dd 206 Gene3D G3DSA:1.10.357.10 1 205 7.3E-44 T 12-10-2018 AFR_26130 f4c3e00bd6f30fe276acef6a22255cfe 431 Gene3D G3DSA:3.40.190.10 25 429 2.4E-57 T 12-10-2018 AFR_26130 f4c3e00bd6f30fe276acef6a22255cfe 431 Pfam PF01547 Bacterial extracellular solute-binding protein 42 335 2.4E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_26130 f4c3e00bd6f30fe276acef6a22255cfe 431 SUPERFAMILY SSF53850 11 428 3.7E-60 T 12-10-2018 AFR_10450 8abdac1c8fee8e7d212f3e767c2b4604 272 Pfam PF08241 Methyltransferase domain 74 170 8.2E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_10450 8abdac1c8fee8e7d212f3e767c2b4604 272 Gene3D G3DSA:3.40.50.150 58 256 4.3E-39 T 12-10-2018 AFR_10450 8abdac1c8fee8e7d212f3e767c2b4604 272 SUPERFAMILY SSF53335 27 252 5.57E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 SUPERFAMILY SSF50341 167 307 4.19E-17 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 SUPERFAMILY SSF50341 356 467 1.83E-8 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 Gene3D G3DSA:2.30.30.40 10 133 7.5E-16 T 12-10-2018 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 SUPERFAMILY SSF50341 9 139 8.24E-20 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 Gene3D G3DSA:2.40.50.180 23 138 7.5E-16 T 12-10-2018 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 Pfam PF01584 CheW-like domain 9 138 1.6E-20 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 Pfam PF01584 CheW-like domain 171 304 1.1E-16 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 Pfam PF01584 CheW-like domain 350 485 2.2E-13 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 Gene3D G3DSA:2.30.30.40 182 290 1.8E-9 T 12-10-2018 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 Gene3D G3DSA:2.40.50.180 189 255 1.8E-9 T 12-10-2018 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 SMART SM00260 345 485 0.0013 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 SMART SM00260 2 139 3.4E-13 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40295 f26983569f91de78a2c27dbf6a98ee40 491 SMART SM00260 166 303 2.8E-4 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_24840 02dee639fe73517be4b8968869f13a17 547 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 546 4.6E-283 T 12-10-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-6981|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7900|MetaCyc: PWY-7902 AFR_24840 02dee639fe73517be4b8968869f13a17 547 SUPERFAMILY SSF53738 307 449 1.09E-31 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 180 5.5E-36 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Gene3D G3DSA:3.30.310.50 445 547 2.5E-35 T 12-10-2018 AFR_24840 02dee639fe73517be4b8968869f13a17 547 SUPERFAMILY SSF53738 26 236 4.94E-49 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Gene3D G3DSA:3.40.120.10 17 221 3.9E-69 T 12-10-2018 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Gene3D G3DSA:3.40.120.10 222 319 1.1E-45 T 12-10-2018 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 322 442 5.9E-27 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 SUPERFAMILY SSF55957 435 546 1.15E-20 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Gene3D G3DSA:3.40.120.10 320 444 3.2E-34 T 12-10-2018 AFR_24840 02dee639fe73517be4b8968869f13a17 547 SUPERFAMILY SSF53738 211 318 1.53E-8 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 318 8.5E-16 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_24840 02dee639fe73517be4b8968869f13a17 547 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 491 540 2.4E-9 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_00850 2814c6323a704ca2d8cb7a35b5894e6e 402 Pfam PF08281 Sigma-70, region 4 104 154 4.6E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_00850 2814c6323a704ca2d8cb7a35b5894e6e 402 Pfam PF04542 Sigma-70 region 2 9 75 2.6E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_00850 2814c6323a704ca2d8cb7a35b5894e6e 402 SUPERFAMILY SSF88946 6 91 3.22E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_00850 2814c6323a704ca2d8cb7a35b5894e6e 402 Gene3D G3DSA:1.10.1740.10 4 91 1.5E-8 T 12-10-2018 AFR_00850 2814c6323a704ca2d8cb7a35b5894e6e 402 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 156 5.1E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_00850 2814c6323a704ca2d8cb7a35b5894e6e 402 Gene3D G3DSA:1.10.10.10 109 159 6.4E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00850 2814c6323a704ca2d8cb7a35b5894e6e 402 SUPERFAMILY SSF88659 98 156 5.45E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_32175 555be6bb7fff35461a2a7f1f97d698f5 276 Gene3D G3DSA:3.40.50.150 4 276 2.1E-111 T 12-10-2018 AFR_32175 555be6bb7fff35461a2a7f1f97d698f5 276 Pfam PF04672 S-adenosyl methyltransferase 11 276 1.0E-105 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_32175 555be6bb7fff35461a2a7f1f97d698f5 276 SUPERFAMILY SSF53335 21 261 1.85E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_32175 555be6bb7fff35461a2a7f1f97d698f5 276 PIRSF PIRSF017393 3 276 2.8E-104 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_32885 3a9a88fdacd588eb1e1a06256970a8c8 302 Gene3D G3DSA:3.40.50.880 2 211 2.1E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_32885 3a9a88fdacd588eb1e1a06256970a8c8 302 Pfam PF12833 Helix-turn-helix domain 234 296 3.0E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_32885 3a9a88fdacd588eb1e1a06256970a8c8 302 SMART SM00342 228 300 3.9E-6 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_32885 3a9a88fdacd588eb1e1a06256970a8c8 302 SUPERFAMILY SSF52317 3 193 1.56E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_32885 3a9a88fdacd588eb1e1a06256970a8c8 302 Pfam PF01965 DJ-1/PfpI family 3 172 1.1E-18 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_32885 3a9a88fdacd588eb1e1a06256970a8c8 302 Gene3D G3DSA:1.10.10.60 212 300 8.9E-18 T 12-10-2018 AFR_32885 3a9a88fdacd588eb1e1a06256970a8c8 302 SUPERFAMILY SSF46689 212 262 1.34E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_23605 660c8259da54119a67d77dd00206aa7e 215 Gene3D G3DSA:3.40.50.150 17 203 3.4E-28 T 12-10-2018 AFR_23605 660c8259da54119a67d77dd00206aa7e 215 Pfam PF08241 Methyltransferase domain 50 141 8.5E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_23605 660c8259da54119a67d77dd00206aa7e 215 SUPERFAMILY SSF53335 46 202 1.03E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_37335 f71fa69819594e5e593f8532446db61a 480 SUPERFAMILY SSF52540 92 362 1.24E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37335 f71fa69819594e5e593f8532446db61a 480 SUPERFAMILY SSF47917 362 477 3.14E-48 T 12-10-2018 AFR_37335 f71fa69819594e5e593f8532446db61a 480 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37335 f71fa69819594e5e593f8532446db61a 480 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 14 477 3.6E-240 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFR_37335 f71fa69819594e5e593f8532446db61a 480 SMART SM00382 158 398 2.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37335 f71fa69819594e5e593f8532446db61a 480 Gene3D G3DSA:1.10.1140.10 362 480 5.6E-51 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37335 f71fa69819594e5e593f8532446db61a 480 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 17 88 5.8E-23 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37335 f71fa69819594e5e593f8532446db61a 480 Hamap MF_01347 ATP synthase subunit beta [atpB]. 12 477 54.485 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFR_37335 f71fa69819594e5e593f8532446db61a 480 SUPERFAMILY SSF50615 14 90 3.66E-26 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37335 f71fa69819594e5e593f8532446db61a 480 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 359 1.4E-62 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37335 f71fa69819594e5e593f8532446db61a 480 Gene3D G3DSA:3.40.50.300 91 361 2.3E-100 T 12-10-2018 AFR_37335 f71fa69819594e5e593f8532446db61a 480 Gene3D G3DSA:2.40.10.170 11 90 1.7E-29 T 12-10-2018 AFR_07210 b7e90be2d22ff9e463091db95ac59989 218 Gene3D G3DSA:3.40.50.2300 1 120 1.6E-30 T 12-10-2018 AFR_07210 b7e90be2d22ff9e463091db95ac59989 218 Pfam PF00072 Response regulator receiver domain 3 112 1.9E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_07210 b7e90be2d22ff9e463091db95ac59989 218 Gene3D G3DSA:1.10.10.10 121 218 3.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07210 b7e90be2d22ff9e463091db95ac59989 218 SMART SM00862 145 217 3.7E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_07210 b7e90be2d22ff9e463091db95ac59989 218 SMART SM00448 1 112 1.8E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_07210 b7e90be2d22ff9e463091db95ac59989 218 SUPERFAMILY SSF52172 1 167 1.76E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_07210 b7e90be2d22ff9e463091db95ac59989 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 217 1.2E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 Gene3D G3DSA:3.40.50.2300 156 281 2.9E-64 T 12-10-2018 AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 Gene3D G3DSA:3.40.50.2300 60 297 2.9E-64 T 12-10-2018 AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 Gene3D G3DSA:1.10.260.40 1 59 2.2E-22 T 12-10-2018 AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 SUPERFAMILY SSF53822 66 324 2.36E-60 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 1.1E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 SMART SM00354 6 76 6.5E-26 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 Pfam PF13377 Periplasmic binding protein-like domain 164 322 2.5E-37 T 12-10-2018 AFR_19505 f816efea111af2e6fb913e9a629f08ee 351 SUPERFAMILY SSF47413 6 64 1.38E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 SUPERFAMILY SSF55874 120 282 4.06E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 SMART SM00388 62 130 3.9E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 SMART SM00387 176 284 2.4E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 Gene3D G3DSA:3.30.565.10 128 282 1.5E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 PRINTS PR00344 Bacterial sensor protein C-terminal signature 231 241 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 PRINTS PR00344 Bacterial sensor protein C-terminal signature 268 281 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 PRINTS PR00344 Bacterial sensor protein C-terminal signature 213 227 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 PRINTS PR00344 Bacterial sensor protein C-terminal signature 244 262 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 Pfam PF00512 His Kinase A (phospho-acceptor) domain 63 130 2.5E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 177 282 4.0E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 Gene3D G3DSA:1.10.287.130 49 127 4.4E-13 T 12-10-2018 AFR_24405 bfd7022246c895da8d8836c4dcc5da2a 285 SUPERFAMILY SSF47384 48 130 1.39E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_03970 49108d07ddd1de12d39bbac35b1bc769 94 Pfam PF01713 Smr domain 5 82 1.4E-11 T 12-10-2018 IPR002625 Smr domain AFR_03970 49108d07ddd1de12d39bbac35b1bc769 94 SUPERFAMILY SSF160443 4 76 6.8E-5 T 12-10-2018 IPR036063 Smr domain superfamily AFR_03970 49108d07ddd1de12d39bbac35b1bc769 94 Gene3D G3DSA:3.30.1370.110 1 82 1.1E-11 T 12-10-2018 AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 Pfam PF00563 EAL domain 506 748 9.6E-71 T 12-10-2018 IPR001633 EAL domain AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 Pfam PF00990 Diguanylate cyclase, GGDEF domain 338 483 2.0E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 333 485 1.7E-32 T 12-10-2018 IPR000160 GGDEF domain AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 SUPERFAMILY SSF141868 506 760 1.57E-78 T 12-10-2018 IPR035919 EAL domain superfamily AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 Gene3D G3DSA:3.20.20.450 503 766 3.2E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 SUPERFAMILY SSF55073 342 491 5.34E-37 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 SMART SM00267 326 489 1.7E-46 T 12-10-2018 IPR000160 GGDEF domain AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 Gene3D G3DSA:3.30.70.270 331 502 8.9E-45 T 12-10-2018 AFR_27610 a1a6ec97a2de468aa135728b9a656db7 767 SMART SM00052 499 753 7.0E-103 T 12-10-2018 IPR001633 EAL domain AFR_12955 76d0a8158c924909cffce793d6db59e7 322 Gene3D G3DSA:3.40.50.880 1 205 5.9E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_12955 76d0a8158c924909cffce793d6db59e7 322 Pfam PF12833 Helix-turn-helix domain 237 315 7.5E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_12955 76d0a8158c924909cffce793d6db59e7 322 SUPERFAMILY SSF46689 222 264 3.05E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12955 76d0a8158c924909cffce793d6db59e7 322 SMART SM00342 231 314 1.8E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_12955 76d0a8158c924909cffce793d6db59e7 322 Gene3D G3DSA:1.10.10.60 219 320 3.3E-25 T 12-10-2018 AFR_12955 76d0a8158c924909cffce793d6db59e7 322 Pfam PF01965 DJ-1/PfpI family 3 175 1.4E-11 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_12955 76d0a8158c924909cffce793d6db59e7 322 SUPERFAMILY SSF46689 268 318 2.69E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12955 76d0a8158c924909cffce793d6db59e7 322 SUPERFAMILY SSF52317 2 197 2.71E-38 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_36175 48cc00ceb494c39ef3147a3ecb87e93e 531 Gene3D G3DSA:3.50.50.60 223 329 1.3E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_36175 48cc00ceb494c39ef3147a3ecb87e93e 531 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 51 2.0E-8 T 12-10-2018 AFR_36175 48cc00ceb494c39ef3147a3ecb87e93e 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 230 245 1.2E-5 T 12-10-2018 AFR_36175 48cc00ceb494c39ef3147a3ecb87e93e 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.2E-5 T 12-10-2018 AFR_36175 48cc00ceb494c39ef3147a3ecb87e93e 531 SUPERFAMILY SSF51905 6 529 1.48E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_36175 48cc00ceb494c39ef3147a3ecb87e93e 531 Gene3D G3DSA:3.50.50.60 8 136 2.2E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_36175 48cc00ceb494c39ef3147a3ecb87e93e 531 Pfam PF01593 Flavin containing amine oxidoreductase 228 321 7.9E-5 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_23745 ec104e19629862c38522fafd4045bca4 336 SUPERFAMILY SSF51569 2 275 2.01E-61 T 12-10-2018 AFR_23745 ec104e19629862c38522fafd4045bca4 336 Gene3D G3DSA:1.10.8.60 274 336 2.5E-29 T 12-10-2018 AFR_23745 ec104e19629862c38522fafd4045bca4 336 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 271 332 9.0E-22 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFR_23745 ec104e19629862c38522fafd4045bca4 336 Pfam PF00682 HMGL-like 8 261 6.5E-56 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFR_23745 ec104e19629862c38522fafd4045bca4 336 Gene3D G3DSA:3.20.20.70 1 267 4.5E-76 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_23745 ec104e19629862c38522fafd4045bca4 336 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 336 207.299 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFR_23745 ec104e19629862c38522fafd4045bca4 336 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 4 334 8.7E-165 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFR_23745 ec104e19629862c38522fafd4045bca4 336 SUPERFAMILY SSF89000 287 334 7.85E-16 T 12-10-2018 AFR_23745 ec104e19629862c38522fafd4045bca4 336 Pfam PF07836 DmpG-like communication domain 273 333 6.9E-30 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFR_14105 d2adb1265f0c6698983e02b994a737de 400 Gene3D G3DSA:3.20.20.450 170 399 4.0E-59 T 12-10-2018 IPR035919 EAL domain superfamily AFR_14105 d2adb1265f0c6698983e02b994a737de 400 Pfam PF00563 EAL domain 174 396 3.5E-48 T 12-10-2018 IPR001633 EAL domain AFR_14105 d2adb1265f0c6698983e02b994a737de 400 SMART SM00052 167 399 3.6E-31 T 12-10-2018 IPR001633 EAL domain AFR_14105 d2adb1265f0c6698983e02b994a737de 400 SUPERFAMILY SSF141868 175 397 1.01E-57 T 12-10-2018 IPR035919 EAL domain superfamily AFR_14105 d2adb1265f0c6698983e02b994a737de 400 SMART SM00065 19 167 0.0062 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_14105 d2adb1265f0c6698983e02b994a737de 400 SUPERFAMILY SSF55781 24 163 6.87E-16 T 12-10-2018 AFR_14105 d2adb1265f0c6698983e02b994a737de 400 Gene3D G3DSA:3.30.450.40 22 169 1.2E-8 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_03365 d5502cd83759e83e4b9eb9ad91b975d9 268 SUPERFAMILY SSF51658 9 263 3.01E-46 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_03365 d5502cd83759e83e4b9eb9ad91b975d9 268 Pfam PF01261 Xylose isomerase-like TIM barrel 17 212 1.9E-23 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_03365 d5502cd83759e83e4b9eb9ad91b975d9 268 Gene3D G3DSA:3.20.20.150 1 262 2.9E-58 T 12-10-2018 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 494 83.362 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 481 1.7E-157 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 SUPERFAMILY SSF51412 8 485 2.62E-119 T 12-10-2018 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 PIRSF PIRSF000130 2 495 3.4E-203 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 463 1.2E-185 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 Gene3D G3DSA:3.20.20.70 3 494 1.4E-210 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 SMART SM01240 11 481 0.0 T 12-10-2018 AFR_04950 707e7cb28f975a461100f0d8b311600a 495 SMART SM00116 100 148 2.6E-11 T 12-10-2018 IPR000644 CBS domain AFR_04950 707e7cb28f975a461100f0d8b311600a 495 SMART SM00116 161 209 0.014 T 12-10-2018 IPR000644 CBS domain AFR_04950 707e7cb28f975a461100f0d8b311600a 495 Pfam PF00571 CBS domain 153 205 5.3E-5 T 12-10-2018 IPR000644 CBS domain AFR_04950 707e7cb28f975a461100f0d8b311600a 495 Pfam PF00571 CBS domain 97 144 1.0E-9 T 12-10-2018 IPR000644 CBS domain AFR_04950 707e7cb28f975a461100f0d8b311600a 495 SUPERFAMILY SSF54631 97 206 6.57E-30 T 12-10-2018 AFR_29270 0c7f4c2c0f5d97721cacea6e88a0e210 306 SUPERFAMILY SSF53850 99 298 1.05E-30 T 12-10-2018 AFR_29270 0c7f4c2c0f5d97721cacea6e88a0e210 306 Gene3D G3DSA:3.40.190.290 100 293 2.6E-32 T 12-10-2018 AFR_29270 0c7f4c2c0f5d97721cacea6e88a0e210 306 Pfam PF03466 LysR substrate binding domain 98 295 1.5E-27 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_29270 0c7f4c2c0f5d97721cacea6e88a0e210 306 SUPERFAMILY SSF46785 11 121 6.58E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29270 0c7f4c2c0f5d97721cacea6e88a0e210 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 3.4E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_29270 0c7f4c2c0f5d97721cacea6e88a0e210 306 Gene3D G3DSA:1.10.10.10 11 97 7.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13855 a0daac7ce43e200ca049aafd32127c1f 272 Pfam PF13560 Helix-turn-helix domain 10 84 8.1E-13 T 12-10-2018 AFR_13855 a0daac7ce43e200ca049aafd32127c1f 272 SMART SM00530 28 84 2.2E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_13855 a0daac7ce43e200ca049aafd32127c1f 272 Gene3D G3DSA:1.10.260.40 24 83 6.6E-9 T 12-10-2018 AFR_13855 a0daac7ce43e200ca049aafd32127c1f 272 SUPERFAMILY SSF47413 26 81 3.56E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 Gene3D G3DSA:3.40.50.200 115 393 9.7E-86 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 Pfam PF00082 Subtilase family 145 376 3.7E-44 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 Gene3D G3DSA:2.60.40.10 401 490 3.6E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 Gene3D G3DSA:2.60.40.10 491 575 1.6E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 SUPERFAMILY SSF52743 125 394 5.76E-78 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 193 1.3E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 PRINTS PR00723 Subtilisin serine protease family (S8) signature 335 351 1.3E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 PRINTS PR00723 Subtilisin serine protease family (S8) signature 143 162 1.3E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_04975 6fd0d399cd9eea5df51fb7eb22162ef0 579 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 336 346 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_12730 559f7c582f240d38156a967da3445759 39 Pfam PF01797 Transposase IS200 like 3 35 2.9E-8 T 12-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 AFR_12730 559f7c582f240d38156a967da3445759 39 Gene3D G3DSA:3.30.70.1290 1 39 1.8E-8 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFR_12730 559f7c582f240d38156a967da3445759 39 SUPERFAMILY SSF143422 4 36 9.03E-10 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 107 378 1.4E-101 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 Gene3D G3DSA:1.20.120.140 82 377 2.0E-99 T 12-10-2018 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 Pfam PF02881 SRP54-type protein, helical bundle domain 94 159 1.9E-11 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 SUPERFAMILY SSF52540 175 379 1.73E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 SMART SM00963 83 163 2.3E-20 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 106 379 58.001 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 352 365 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 SMART SM00382 179 355 6.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 SMART SM00962 180 379 6.9E-102 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 SUPERFAMILY SSF47364 79 157 2.09E-17 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 Pfam PF00448 SRP54-type protein, GTPase domain 180 379 1.2E-70 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36435 c98e18cd2b7adfbde588917242bdb8c2 382 Gene3D G3DSA:3.40.50.300 178 367 2.0E-99 T 12-10-2018 AFR_09025 b19f2456466eb3e922b5402f4eb422be 482 SUPERFAMILY SSF50249 10 405 2.97E-83 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_09025 b19f2456466eb3e922b5402f4eb422be 482 SMART SM00955 44 362 4.2E-48 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 AFR_09025 b19f2456466eb3e922b5402f4eb422be 482 Pfam PF00773 RNB domain 46 352 5.6E-37 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 AFR_35590 1e6c8d3152eb31f418feefed8213fe93 473 SMART SM00267 304 473 3.2E-52 T 12-10-2018 IPR000160 GGDEF domain AFR_35590 1e6c8d3152eb31f418feefed8213fe93 473 Pfam PF00990 Diguanylate cyclase, GGDEF domain 315 463 1.8E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_35590 1e6c8d3152eb31f418feefed8213fe93 473 SUPERFAMILY SSF55073 320 462 1.83E-42 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_35590 1e6c8d3152eb31f418feefed8213fe93 473 Gene3D G3DSA:3.30.70.270 301 467 2.3E-51 T 12-10-2018 AFR_35590 1e6c8d3152eb31f418feefed8213fe93 473 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 313 463 3.8E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_16795 0c4e4873e06fa7077e9fbdddf3ef24fe 140 Gene3D G3DSA:1.10.10.10 3 139 5.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16795 0c4e4873e06fa7077e9fbdddf3ef24fe 140 Pfam PF12802 MarR family 28 84 1.2E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_16795 0c4e4873e06fa7077e9fbdddf3ef24fe 140 SUPERFAMILY SSF46785 5 135 3.52E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16795 0c4e4873e06fa7077e9fbdddf3ef24fe 140 SMART SM00347 21 121 7.2E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_16795 0c4e4873e06fa7077e9fbdddf3ef24fe 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 1.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_16795 0c4e4873e06fa7077e9fbdddf3ef24fe 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 1.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_16795 0c4e4873e06fa7077e9fbdddf3ef24fe 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 1.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23480 e870e20799c44b4c636290b864391870 411 SUPERFAMILY SSF56524 277 409 1.83E-34 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_23480 e870e20799c44b4c636290b864391870 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 313 328 6.9E-9 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_23480 e870e20799c44b4c636290b864391870 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 395 408 6.9E-9 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_23480 e870e20799c44b4c636290b864391870 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 379 392 6.9E-9 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_23480 e870e20799c44b4c636290b864391870 411 Pfam PF00174 Oxidoreductase molybdopterin binding domain 277 409 1.6E-25 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFR_23480 e870e20799c44b4c636290b864391870 411 Gene3D G3DSA:3.90.420.10 258 411 2.8E-29 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 SUPERFAMILY SSF88946 8 97 8.11E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 Pfam PF08281 Sigma-70, region 4 110 160 2.2E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 Gene3D G3DSA:1.10.1740.10 3 84 3.3E-9 T 12-10-2018 AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 6 166 1.6E-48 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 Gene3D G3DSA:1.10.10.10 85 168 2.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 164 5.2E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 Pfam PF04542 Sigma-70 region 2 19 83 7.6E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34285 122e2a23a02d4e7e57cbdb3c0687fd7d 177 SUPERFAMILY SSF88659 106 165 8.04E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 330 417 2.2E-14 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 51 460 38.297 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 Gene3D G3DSA:3.20.20.10 70 325 1.7E-160 T 12-10-2018 IPR029066 PLP-binding barrel AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 72 325 1.4E-59 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 315 334 1.8E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 226 239 1.8E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 91 109 1.8E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 417 430 1.8E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 111 123 1.8E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01181 Diaminopimelate decarboxylase signature 427 449 9.3E-25 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01181 Diaminopimelate decarboxylase signature 344 362 9.3E-25 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01181 Diaminopimelate decarboxylase signature 198 207 9.3E-25 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 PRINTS PR01181 Diaminopimelate decarboxylase signature 109 126 9.3E-25 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 SUPERFAMILY SSF50621 301 460 4.81E-49 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 42 459 1.7E-139 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 91 109 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 263 278 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 SUPERFAMILY SSF51419 62 327 2.62E-71 T 12-10-2018 IPR029066 PLP-binding barrel AFR_37490 9bbac1ca2cd38277929b1eee92f67d58 461 Gene3D G3DSA:2.40.37.10 49 456 1.7E-160 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Gene3D G3DSA:3.40.50.12740 13 138 9.7E-29 T 12-10-2018 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Gene3D G3DSA:3.40.50.2300 139 267 3.7E-30 T 12-10-2018 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SUPERFAMILY SSF52172 6 131 1.12E-28 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 550 660 4.7E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Pfam PF00512 His Kinase A (phospho-acceptor) domain 443 507 3.1E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SMART SM00388 441 509 3.4E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Gene3D G3DSA:3.30.565.10 512 660 4.7E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SMART SM00387 550 662 8.3E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SUPERFAMILY SSF55874 509 661 5.11E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SUPERFAMILY SSF47384 425 510 6.47E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SMART SM00448 141 254 1.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SMART SM00448 277 388 1.1E-10 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SMART SM00448 13 126 6.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SUPERFAMILY SSF52172 139 266 4.13E-31 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 SUPERFAMILY SSF52172 274 409 3.84E-21 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 PRINTS PR00344 Bacterial sensor protein C-terminal signature 646 659 2.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 PRINTS PR00344 Bacterial sensor protein C-terminal signature 622 640 2.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 PRINTS PR00344 Bacterial sensor protein C-terminal signature 607 617 2.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 603 2.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Gene3D G3DSA:1.10.287.130 430 511 4.6E-14 T 12-10-2018 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Gene3D G3DSA:3.40.50.2300 277 426 2.9E-19 T 12-10-2018 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Pfam PF00072 Response regulator receiver domain 143 253 2.7E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Pfam PF00072 Response regulator receiver domain 282 388 6.4E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25695 51d53eadb0367a2a13246afe0a4f7a61 663 Pfam PF00072 Response regulator receiver domain 15 124 8.2E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 Gene3D G3DSA:3.90.180.10 2 291 2.0E-68 T 12-10-2018 AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 Gene3D G3DSA:3.40.50.720 108 241 2.0E-68 T 12-10-2018 AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 99 4.5E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 SMART SM00829 18 295 8.7E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 SUPERFAMILY SSF50129 2 129 1.24E-21 T 12-10-2018 IPR011032 GroES-like superfamily AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 SUPERFAMILY SSF51735 97 270 8.77E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 Pfam PF13602 Zinc-binding dehydrogenase 167 294 2.6E-17 T 12-10-2018 AFR_37515 2c09db7e754a5a6c45ba6f88aef87696 297 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 124 145 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 Pfam PF00106 short chain dehydrogenase 8 194 2.2E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 Gene3D G3DSA:3.40.50.720 1 261 3.2E-66 T 12-10-2018 AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 SUPERFAMILY SSF51735 3 259 1.28E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 188 0.0035 T 12-10-2018 AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13970 61d38bb1da756b7b74b4b0321d2ab162 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 SMART SM00359 281 365 1.0E-12 T 12-10-2018 IPR002478 PUA domain GO:0003723 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 371 7.0E-121 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 SUPERFAMILY SSF88697 280 372 6.84E-21 T 12-10-2018 IPR015947 PUA-like superfamily AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 Pfam PF01472 PUA domain 281 347 5.1E-16 T 12-10-2018 IPR002478 PUA domain GO:0003723 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 PIRSF PIRSF000729 7 373 3.0E-120 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 SUPERFAMILY SSF53633 12 260 2.62E-60 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 4.0E-53 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 4.0E-53 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 4.0E-53 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 4.0E-53 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 4.0E-53 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 Gene3D G3DSA:2.30.130.10 271 373 1.0E-27 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 Gene3D G3DSA:3.40.1160.10 2 269 1.7E-80 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 Pfam PF00696 Amino acid kinase family 13 241 4.6E-40 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFR_04160 3445a5bba146cb79bd828db3b76e54a8 373 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 268 35.173 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFR_09665 5976e8cf1e6644f2274810a74a24f9d1 314 SUPERFAMILY SSF51735 116 223 5.32E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_09665 5976e8cf1e6644f2274810a74a24f9d1 314 Gene3D G3DSA:3.40.50.720 127 250 1.7E-56 T 12-10-2018 AFR_09665 5976e8cf1e6644f2274810a74a24f9d1 314 Pfam PF13602 Zinc-binding dehydrogenase 203 304 8.5E-9 T 12-10-2018 AFR_09665 5976e8cf1e6644f2274810a74a24f9d1 314 Gene3D G3DSA:3.90.180.10 10 302 1.7E-56 T 12-10-2018 AFR_09665 5976e8cf1e6644f2274810a74a24f9d1 314 SUPERFAMILY SSF50129 3 152 3.2E-26 T 12-10-2018 IPR011032 GroES-like superfamily AFR_09665 5976e8cf1e6644f2274810a74a24f9d1 314 SMART SM00829 12 304 1.4E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_09665 5976e8cf1e6644f2274810a74a24f9d1 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 4.0E-10 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_38435 15b3ca264abf4aa73fb5f7e1072d4ab1 137 Pfam PF02082 Transcriptional regulator 3 82 5.7E-24 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFR_38435 15b3ca264abf4aa73fb5f7e1072d4ab1 137 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site AFR_38435 15b3ca264abf4aa73fb5f7e1072d4ab1 137 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 130 7.8E-32 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFR_38435 15b3ca264abf4aa73fb5f7e1072d4ab1 137 Gene3D G3DSA:1.10.10.10 1 135 7.2E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38435 15b3ca264abf4aa73fb5f7e1072d4ab1 137 SUPERFAMILY SSF46785 4 130 5.78E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_32975 00e805c418416aeb24bc2b9087fb7f85 160 Pfam PF03073 TspO/MBR family 21 157 2.8E-46 T 12-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 AFR_32975 00e805c418416aeb24bc2b9087fb7f85 160 Gene3D G3DSA:1.20.1260.100 10 160 1.1E-49 T 12-10-2018 IPR038330 TspO/MBR-related superfamily AFR_32975 00e805c418416aeb24bc2b9087fb7f85 160 PIRSF PIRSF005859 7 160 9.5E-47 T 12-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Gene3D G3DSA:3.30.310.50 373 448 1.3E-24 T 12-10-2018 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 SUPERFAMILY SSF53738 260 367 1.65E-27 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Gene3D G3DSA:3.40.120.10 259 342 1.8E-63 T 12-10-2018 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 256 7.1E-20 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Gene3D G3DSA:3.40.120.10 177 365 1.8E-63 T 12-10-2018 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 SUPERFAMILY SSF53738 3 183 1.14E-44 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Gene3D G3DSA:3.40.120.10 1 141 1.7E-44 T 12-10-2018 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 1.9E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 1.9E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 1.9E-12 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 SUPERFAMILY SSF55957 360 447 2.49E-22 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 1.2E-174 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 445 9.6E-14 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 SUPERFAMILY SSF53738 160 258 4.32E-28 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 367 5.0E-31 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 447 44.049 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_04795 345163f5ca1d08200433e7088e2b6c74 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 3.7E-40 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 SMART SM00382 51 206 1.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 SUPERFAMILY SSF52540 33 252 2.71E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 Gene3D G3DSA:3.40.50.300 27 240 9.3E-39 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 Pfam PF13481 AAA domain 40 184 4.2E-17 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 Gene3D G3DSA:3.30.230.10 292 422 3.6E-13 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 PRINTS PR01874 DNA repair protein radA signature 86 103 8.4E-72 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 PRINTS PR01874 DNA repair protein radA signature 175 203 8.4E-72 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 PRINTS PR01874 DNA repair protein radA signature 210 236 8.4E-72 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 PRINTS PR01874 DNA repair protein radA signature 284 307 8.4E-72 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 PRINTS PR01874 DNA repair protein radA signature 136 160 8.4E-72 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 PRINTS PR01874 DNA repair protein radA signature 43 71 8.4E-72 T 12-10-2018 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 TIGRFAM TIGR00416 sms: DNA repair protein RadA 20 417 8.6E-134 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 SUPERFAMILY SSF54211 255 420 1.33E-32 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_41320 94a0df60dc2812343c9d46e2f074b74c 426 Hamap MF_01498 DNA repair protein RadA [radA]. 2 421 37.462 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 385 66.275 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 Gene3D G3DSA:3.40.640.10 55 294 1.1E-133 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 Gene3D G3DSA:3.90.1150.10 24 377 1.1E-133 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 12 384 2.1E-133 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 Pfam PF00202 Aminotransferase class-III 25 384 5.4E-107 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 212 249 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 PIRSF PIRSF000521 163 385 4.9E-30 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 PIRSF PIRSF000521 4 122 5.1E-6 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 PIRSF PIRSF000521 116 146 1.9 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_30230 c25b63d2282f32bfaf27d3f63a61c3e8 385 SUPERFAMILY SSF53383 10 384 4.98E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 SMART SM00304 229 281 1.8E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 464 493 8.8E-26 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 79 94 8.8E-26 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 416 445 8.8E-26 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 310 339 8.8E-26 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 387 414 8.8E-26 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 SMART SM00283 289 543 3.5E-54 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 349 510 8.7E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 Gene3D G3DSA:1.10.287.950 228 544 2.9E-64 T 12-10-2018 AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 Pfam PF12729 Four helix bundle sensory module for signal transduction 22 197 1.1E-17 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_29045 31c1ee3c9410394f0f1cdb00a2ef3044 544 SUPERFAMILY SSF58104 249 542 2.22E-61 T 12-10-2018 AFR_29645 9cf389e3df73c3804bed046d591c03e1 231 Gene3D G3DSA:3.90.1200.10 64 231 1.8E-57 T 12-10-2018 AFR_29645 9cf389e3df73c3804bed046d591c03e1 231 Pfam PF01636 Phosphotransferase enzyme family 23 220 2.3E-23 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_29645 9cf389e3df73c3804bed046d591c03e1 231 Gene3D G3DSA:3.30.200.20 1 58 9.4E-10 T 12-10-2018 AFR_29645 9cf389e3df73c3804bed046d591c03e1 231 SUPERFAMILY SSF56112 6 231 1.2E-39 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_29645 9cf389e3df73c3804bed046d591c03e1 231 PIRSF PIRSF000706 1 231 7.0E-64 T 12-10-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 AFR_34690 314559579eb17cdfbe69edec07cad36f 562 Pfam PF00501 AMP-binding enzyme 59 447 4.9E-78 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_34690 314559579eb17cdfbe69edec07cad36f 562 Gene3D G3DSA:3.40.50.12780 16 440 4.1E-116 T 12-10-2018 AFR_34690 314559579eb17cdfbe69edec07cad36f 562 Gene3D G3DSA:3.30.300.30 441 551 1.3E-20 T 12-10-2018 AFR_34690 314559579eb17cdfbe69edec07cad36f 562 SUPERFAMILY SSF56801 19 542 5.1E-133 T 12-10-2018 AFR_34690 314559579eb17cdfbe69edec07cad36f 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 2.7E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_17310 c34cce519fb484333b1fd8d80dd0da0a 320 Pfam PF14525 AraC-binding-like domain 14 195 2.3E-28 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_17310 c34cce519fb484333b1fd8d80dd0da0a 320 SMART SM00342 232 318 2.7E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_17310 c34cce519fb484333b1fd8d80dd0da0a 320 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 314 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_17310 c34cce519fb484333b1fd8d80dd0da0a 320 Gene3D G3DSA:1.10.10.60 215 320 9.2E-34 T 12-10-2018 AFR_17310 c34cce519fb484333b1fd8d80dd0da0a 320 SUPERFAMILY SSF46689 216 266 1.26E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_17310 c34cce519fb484333b1fd8d80dd0da0a 320 Pfam PF12833 Helix-turn-helix domain 238 319 1.6E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_05345 dcb3a83f1e62827b486cd45a9031dec4 301 Gene3D G3DSA:3.30.420.150 124 301 1.1E-60 T 12-10-2018 AFR_05345 dcb3a83f1e62827b486cd45a9031dec4 301 Pfam PF02541 Ppx/GppA phosphatase family 16 296 1.2E-66 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 AFR_05345 dcb3a83f1e62827b486cd45a9031dec4 301 SUPERFAMILY SSF53067 127 300 1.19E-39 T 12-10-2018 AFR_05345 dcb3a83f1e62827b486cd45a9031dec4 301 SUPERFAMILY SSF53067 2 123 2.05E-35 T 12-10-2018 AFR_05345 dcb3a83f1e62827b486cd45a9031dec4 301 Gene3D G3DSA:3.30.420.40 1 123 2.6E-47 T 12-10-2018 AFR_14320 a87bd5ff4ec0f2ddeb755abc8bc70877 493 Gene3D G3DSA:3.30.420.40 12 250 1.4E-43 T 12-10-2018 AFR_14320 a87bd5ff4ec0f2ddeb755abc8bc70877 493 SUPERFAMILY SSF53067 261 490 1.3E-29 T 12-10-2018 AFR_14320 a87bd5ff4ec0f2ddeb755abc8bc70877 493 Gene3D G3DSA:3.30.420.40 261 492 8.5E-46 T 12-10-2018 AFR_14320 a87bd5ff4ec0f2ddeb755abc8bc70877 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 17 222 1.2E-27 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFR_14320 a87bd5ff4ec0f2ddeb755abc8bc70877 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 300 447 4.8E-18 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_14320 a87bd5ff4ec0f2ddeb755abc8bc70877 493 SUPERFAMILY SSF53067 17 262 2.22E-38 T 12-10-2018 AFR_14320 a87bd5ff4ec0f2ddeb755abc8bc70877 493 PIRSF PIRSF000538 15 492 1.3E-69 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_23460 97d7279fe3ae731dfa4357e4772bc89c 244 Gene3D G3DSA:3.40.50.720 2 244 3.2E-27 T 12-10-2018 AFR_23460 97d7279fe3ae731dfa4357e4772bc89c 244 Pfam PF13460 NAD(P)H-binding 7 171 2.1E-9 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_23460 97d7279fe3ae731dfa4357e4772bc89c 244 SUPERFAMILY SSF51735 1 214 1.61E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 Gene3D G3DSA:1.10.540.10 22 129 9.8E-91 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 SUPERFAMILY SSF56645 13 247 9.69E-56 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 126 1.3E-13 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 Gene3D G3DSA:2.40.110.10 130 239 9.8E-91 T 12-10-2018 AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 SUPERFAMILY SSF47203 240 391 3.22E-28 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 228 1.9E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 379 2.0E-23 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_13420 faa9382e2178612aba522e07fcac8ba6 542 Gene3D G3DSA:1.20.140.10 240 384 9.8E-91 T 12-10-2018 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 SMART SM00382 113 265 9.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.47 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 311 3.4E-50 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 Gene3D G3DSA:1.10.8.60 316 421 7.3E-35 T 12-10-2018 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 SUPERFAMILY SSF52540 58 403 3.84E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 SUPERFAMILY SSF57716 11 46 1.38E-11 T 12-10-2018 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 Gene3D G3DSA:3.40.50.300 54 314 3.7E-105 T 12-10-2018 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 4.5E-195 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 SMART SM00994 10 49 1.1E-23 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 SMART SM01086 317 404 4.5E-28 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 390 9.5E-15 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_07550 17d9fe40f0d7a6b2b360eaf6e573bec0 430 Gene3D G3DSA:3.30.50.30 3 50 5.5E-24 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily AFR_15535 5d64f444590c39315680ddef463e10b4 986 Pfam PF07691 PA14 domain 33 168 5.6E-21 T 12-10-2018 IPR011658 PA14 domain AFR_15535 5d64f444590c39315680ddef463e10b4 986 Pfam PF06439 Domain of Unknown Function (DUF1080) 796 983 1.0E-36 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 AFR_15535 5d64f444590c39315680ddef463e10b4 986 SMART SM00758 31 171 3.6E-30 T 12-10-2018 IPR011658 PA14 domain AFR_15535 5d64f444590c39315680ddef463e10b4 986 Pfam PF16990 Carbohydrate binding module (family 35) 663 790 2.1E-10 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_15535 5d64f444590c39315680ddef463e10b4 986 SUPERFAMILY SSF50952 204 516 6.15E-12 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_15535 5d64f444590c39315680ddef463e10b4 986 SUPERFAMILY SSF49785 663 789 2.79E-14 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15535 5d64f444590c39315680ddef463e10b4 986 Gene3D G3DSA:2.60.120.560 765 984 2.7E-69 T 12-10-2018 AFR_15535 5d64f444590c39315680ddef463e10b4 986 Gene3D G3DSA:2.60.120.380 75 164 3.2E-13 T 12-10-2018 AFR_15535 5d64f444590c39315680ddef463e10b4 986 SUPERFAMILY SSF56988 62 177 1.7E-17 T 12-10-2018 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 52 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 PIRSF PIRSF006092 4 161 1.3E-29 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 Gene3D G3DSA:3.10.50.30 80 162 1.8E-10 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 SUPERFAMILY SSF54534 83 158 4.05E-12 T 12-10-2018 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 160 27.818 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 SUPERFAMILY SSF46557 8 80 8.24E-22 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 Pfam PF03449 Transcription elongation factor, N-terminal 10 78 9.8E-23 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 159 2.5E-17 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AFR_05520 6b0185d171c054c43a4658f0c1e3e487 164 Gene3D G3DSA:1.10.287.180 7 78 5.8E-20 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 AFR_38850 9088c45077f54bd142e434a23a523d9a 242 Gene3D G3DSA:3.40.630.30 4 202 2.9E-24 T 12-10-2018 AFR_38850 9088c45077f54bd142e434a23a523d9a 242 SUPERFAMILY SSF55729 4 138 4.17E-6 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 Gene3D G3DSA:3.30.70.920 61 141 1.0E-20 T 12-10-2018 AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 1.8E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 1.8E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 1.8E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 SMART SM00344 8 115 3.2E-26 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 Pfam PF13404 AsnC-type helix-turn-helix domain 8 48 1.6E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 Gene3D G3DSA:1.10.10.10 1 58 7.9E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 SUPERFAMILY SSF46785 7 68 6.93E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 Pfam PF01037 Lrp/AsnC ligand binding domain 75 144 1.7E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_41145 1d1a4a3d3359f5af720911c1fba0c5df 161 SUPERFAMILY SSF54909 68 154 1.01E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 SUPERFAMILY SSF81624 2 140 2.62E-21 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 138 218 8.3E-16 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 Gene3D G3DSA:3.20.190.10 2 123 7.7E-14 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 SMART SM00898 2 124 3.0E-21 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 SMART SM01232 138 225 6.4E-23 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 Pfam PF06827 Zinc finger found in FPG and IleRS 243 270 2.0E-5 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 84 1.5E-13 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 SUPERFAMILY SSF57716 227 271 1.85E-9 T 12-10-2018 AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 SUPERFAMILY SSF46946 137 218 1.23E-21 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFR_42420 e0a6d52f071520e18693bb22509f1f38 286 Gene3D G3DSA:1.10.8.50 140 271 5.4E-32 T 12-10-2018 AFR_04740 c8b496799f299a5e139ffd2d929dffac 249 Gene3D G3DSA:3.40.50.300 1 237 3.7E-66 T 12-10-2018 AFR_04740 c8b496799f299a5e139ffd2d929dffac 249 Pfam PF00005 ABC transporter 21 160 3.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04740 c8b496799f299a5e139ffd2d929dffac 249 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_04740 c8b496799f299a5e139ffd2d929dffac 249 SUPERFAMILY SSF52540 1 228 9.55E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04740 c8b496799f299a5e139ffd2d929dffac 249 SMART SM00382 30 211 2.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21220 65f75bfa5f62c7b0648e9c6c422c2df0 163 Pfam PF04542 Sigma-70 region 2 15 76 4.8E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_21220 65f75bfa5f62c7b0648e9c6c422c2df0 163 SUPERFAMILY SSF88946 5 81 3.77E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_21220 65f75bfa5f62c7b0648e9c6c422c2df0 163 SUPERFAMILY SSF88659 95 154 2.06E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_21220 65f75bfa5f62c7b0648e9c6c422c2df0 163 Gene3D G3DSA:1.10.10.10 86 158 1.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21220 65f75bfa5f62c7b0648e9c6c422c2df0 163 Pfam PF08281 Sigma-70, region 4 100 150 2.5E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_21220 65f75bfa5f62c7b0648e9c6c422c2df0 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 154 1.4E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_21220 65f75bfa5f62c7b0648e9c6c422c2df0 163 Gene3D G3DSA:1.10.1740.10 1 79 6.2E-10 T 12-10-2018 AFR_17240 a3161c10c8454ed9931e2c3df794b5b4 353 SUPERFAMILY SSF75005 20 289 6.44E-36 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_17240 a3161c10c8454ed9931e2c3df794b5b4 353 Gene3D G3DSA:2.115.10.20 25 336 8.3E-49 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_17240 a3161c10c8454ed9931e2c3df794b5b4 353 Pfam PF04616 Glycosyl hydrolases family 43 35 284 1.4E-27 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 12-10-2018 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 Gene3D G3DSA:3.40.50.2300 71 329 1.5E-73 T 12-10-2018 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 Pfam PF13377 Periplasmic binding protein-like domain 173 337 7.6E-38 T 12-10-2018 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 53 2.1E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 Gene3D G3DSA:3.40.50.2300 165 334 1.5E-73 T 12-10-2018 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 Gene3D G3DSA:1.10.260.40 5 64 7.5E-21 T 12-10-2018 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 SMART SM00354 6 76 2.0E-21 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 SUPERFAMILY SSF53822 66 338 3.26E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_03270 5823f81773864f5ab00f2baa5b97f372 344 SUPERFAMILY SSF47413 6 64 2.81E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 SUPERFAMILY SSF52374 9 334 1.99E-95 T 12-10-2018 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 7 335 41.659 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 Gene3D G3DSA:3.40.50.620 10 333 2.3E-128 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 Pfam PF00579 tRNA synthetases class I (W and Y) 6 289 1.2E-81 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 2.9E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 2.9E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 2.9E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 2.9E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 Gene3D G3DSA:1.10.240.10 192 302 2.3E-128 T 12-10-2018 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 7 334 1.0E-106 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_39625 d906f7c27e5158b0539f3b9fc846f371 341 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 26 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 SMART SM00306 2285 2390 2.2E-7 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 SMART SM00458 1751 1885 1.8E-11 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 Pfam PF07591 Pretoxin HINT domain 2301 2433 3.1E-14 T 12-10-2018 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1979 2060 9.0E-16 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 Pfam PF05593 RHS Repeat 1324 1362 4.7E-5 T 12-10-2018 IPR031325 RHS repeat AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 Gene3D G3DSA:2.180.10.10 1443 1755 2.0E-10 T 12-10-2018 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 Gene3D G3DSA:2.180.10.10 1871 2060 6.9E-14 T 12-10-2018 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 Gene3D G3DSA:2.80.10.50 1756 1849 5.1E-11 T 12-10-2018 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 Gene3D G3DSA:2.170.16.10 2284 2433 3.5E-41 T 12-10-2018 AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 Pfam PF00652 Ricin-type beta-trefoil lectin domain 1759 1882 1.4E-16 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 SUPERFAMILY SSF50370 1759 1882 1.99E-21 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_03690 7f0df42a5d0a748a94ce4017db903dad 2574 SUPERFAMILY SSF51294 2288 2432 5.76E-18 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 SMART SM00267 319 490 6.5E-60 T 12-10-2018 IPR000160 GGDEF domain AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 Pfam PF00563 EAL domain 501 738 6.3E-73 T 12-10-2018 IPR001633 EAL domain AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 SUPERFAMILY SSF55073 334 491 3.37E-48 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 SUPERFAMILY SSF141868 501 750 8.37E-86 T 12-10-2018 IPR035919 EAL domain superfamily AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 Gene3D G3DSA:3.20.20.450 500 755 8.5E-99 T 12-10-2018 IPR035919 EAL domain superfamily AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 Gene3D G3DSA:3.30.70.270 331 499 1.0E-53 T 12-10-2018 AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 SMART SM00052 495 743 2.2E-115 T 12-10-2018 IPR001633 EAL domain AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 Pfam PF00990 Diguanylate cyclase, GGDEF domain 329 485 2.5E-44 T 12-10-2018 IPR000160 GGDEF domain AFR_14185 5e453a9e8a10bd949153ea2f85aa488a 758 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 327 489 6.2E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_07630 d09039c1e2bd630296c3ceeb21fba517 228 SUPERFAMILY SSF69593 5 216 2.09E-47 T 12-10-2018 AFR_07630 d09039c1e2bd630296c3ceeb21fba517 228 SMART SM00563 36 155 3.4E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_07630 d09039c1e2bd630296c3ceeb21fba517 228 Pfam PF01553 Acyltransferase 22 152 5.2E-22 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 SMART SM00450 144 271 8.0E-22 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 SMART SM00450 8 122 5.1E-23 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 ProSitePatterns PS00380 Rhodanese signature 1. 34 45 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 Pfam PF00581 Rhodanese-like domain 9 118 1.1E-17 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 Pfam PF00581 Rhodanese-like domain 149 266 1.3E-16 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 Gene3D G3DSA:3.40.250.10 1 141 3.3E-42 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 SUPERFAMILY SSF52821 5 137 1.7E-37 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 Gene3D G3DSA:3.40.250.10 142 277 1.1E-41 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 SUPERFAMILY SSF52821 159 275 3.8E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_40730 7fb5f41e79193e060dbafc8b52b7bea1 282 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFR_18930 f97a25556f713c0da650a7caf3814243 373 SUPERFAMILY SSF49384 272 366 1.67E-24 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_18930 f97a25556f713c0da650a7caf3814243 373 SMART SM00637 277 370 1.7E-27 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18930 f97a25556f713c0da650a7caf3814243 373 Gene3D G3DSA:2.70.50.50 29 227 9.3E-69 T 12-10-2018 AFR_18930 f97a25556f713c0da650a7caf3814243 373 Pfam PF00553 Cellulose binding domain 277 363 3.7E-20 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18930 f97a25556f713c0da650a7caf3814243 373 SUPERFAMILY SSF81296 29 226 7.7E-44 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_18930 f97a25556f713c0da650a7caf3814243 373 Gene3D G3DSA:2.60.40.290 274 373 3.6E-25 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_18930 f97a25556f713c0da650a7caf3814243 373 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 29 222 4.9E-40 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal AFR_14195 b6528655aa11604cce9978d7ab83b905 193 Gene3D G3DSA:3.40.630.30 13 159 1.7E-29 T 12-10-2018 AFR_14195 b6528655aa11604cce9978d7ab83b905 193 SUPERFAMILY SSF55729 13 155 2.88E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_14195 b6528655aa11604cce9978d7ab83b905 193 Pfam PF00583 Acetyltransferase (GNAT) family 57 149 1.5E-12 T 12-10-2018 IPR000182 GNAT domain AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 SUPERFAMILY SSF56672 97 304 1.56E-12 T 12-10-2018 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 117 306 6.8E-20 T 12-10-2018 IPR000477 Reverse transcriptase domain AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 118 130 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 265 276 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 315 321 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 149 163 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 184 194 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 232 245 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 165 183 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_03660 98bf943db3c50f9b0cf3263eb080177f 390 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 250 263 2.1E-36 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFR_40475 fe51de8fb579a9c9881252941085dff7 403 SUPERFAMILY SSF117143 93 363 7.98E-62 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like AFR_40475 fe51de8fb579a9c9881252941085dff7 403 Pfam PF00460 Flagella basal body rod protein 8 35 1.4E-10 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFR_40475 fe51de8fb579a9c9881252941085dff7 403 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 323 401 2.4E-22 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFR_40475 fe51de8fb579a9c9881252941085dff7 403 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 384 8.5E-85 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G AFR_18340 4a3150b625ad1b9a3fb04bbd5cadd472 689 Gene3D G3DSA:2.120.10.30 66 481 1.2E-47 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_18340 4a3150b625ad1b9a3fb04bbd5cadd472 689 Gene3D G3DSA:2.60.120.560 499 682 1.5E-11 T 12-10-2018 AFR_18340 4a3150b625ad1b9a3fb04bbd5cadd472 689 Pfam PF07995 Glucose / Sorbosone dehydrogenase 126 417 4.3E-23 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_18340 4a3150b625ad1b9a3fb04bbd5cadd472 689 SUPERFAMILY SSF50952 114 353 2.48E-10 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_39390 276c664e2eefef551955c6f1926e8a2d 190 Pfam PF13305 WHG domain 86 169 6.7E-16 T 12-10-2018 IPR025996 WHG domain AFR_39390 276c664e2eefef551955c6f1926e8a2d 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39390 276c664e2eefef551955c6f1926e8a2d 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39390 276c664e2eefef551955c6f1926e8a2d 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 9.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39390 276c664e2eefef551955c6f1926e8a2d 190 Gene3D G3DSA:1.10.357.10 1 190 2.2E-51 T 12-10-2018 AFR_39390 276c664e2eefef551955c6f1926e8a2d 190 SUPERFAMILY SSF46689 6 75 1.49E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_39390 276c664e2eefef551955c6f1926e8a2d 190 SUPERFAMILY SSF48498 81 188 5.11E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_15360 67ae808ed580694f4380d99ebb8b9fc1 280 Pfam PF13560 Helix-turn-helix domain 8 86 1.2E-16 T 12-10-2018 AFR_15360 67ae808ed580694f4380d99ebb8b9fc1 280 Gene3D G3DSA:3.30.450.180 110 269 4.7E-11 T 12-10-2018 AFR_15360 67ae808ed580694f4380d99ebb8b9fc1 280 Gene3D G3DSA:1.10.260.40 5 92 2.5E-8 T 12-10-2018 AFR_15360 67ae808ed580694f4380d99ebb8b9fc1 280 SUPERFAMILY SSF47413 28 79 2.06E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_15360 67ae808ed580694f4380d99ebb8b9fc1 280 SMART SM00530 11 83 2.6E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 Gene3D G3DSA:3.90.400.10 105 174 2.9E-171 T 12-10-2018 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 SUPERFAMILY SSF51011 466 545 7.92E-5 T 12-10-2018 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 SUPERFAMILY SSF51445 6 460 1.06E-105 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 PRINTS PR00110 Alpha-amylase signature 304 316 3.0E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 PRINTS PR00110 Alpha-amylase signature 196 207 3.0E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 PRINTS PR00110 Alpha-amylase signature 94 105 3.0E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 Pfam PF00128 Alpha amylase, catalytic domain 30 386 2.8E-63 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 SMART SM00642 18 421 1.1E-74 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 Gene3D G3DSA:3.20.20.80 6 459 2.9E-171 T 12-10-2018 AFR_13355 cc3028ada66e04f769ea36d44ef1e3a2 551 Gene3D G3DSA:2.60.40.1180 466 545 1.1E-5 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 Pfam PF02811 PHP domain 105 192 6.8E-8 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 Gene3D G3DSA:1.10.150.110 4 85 1.2E-8 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 SUPERFAMILY SSF47802 4 84 7.06E-10 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 SMART SM00481 104 184 7.1E-18 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 SUPERFAMILY SSF89550 103 346 3.53E-49 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 Pfam PF14716 Helix-hairpin-helix domain 8 72 1.8E-12 T 12-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 PIRSF PIRSF036978 2 352 7.2E-149 T 12-10-2018 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 AFR_41930 d59b43c55bf46e2705f19eb2a41c5f3e 358 Gene3D G3DSA:3.20.20.140 97 356 9.5E-68 T 12-10-2018 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 Pfam PF00549 CoA-ligase 158 275 2.0E-14 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 1.3E-34 T 12-10-2018 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 1.3E-34 T 12-10-2018 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 1.3E-34 T 12-10-2018 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 1.3E-34 T 12-10-2018 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 291 3.9E-126 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 SMART SM00881 4 104 6.4E-32 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 Gene3D G3DSA:3.40.50.720 1 129 4.3E-47 T 12-10-2018 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 38.988 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 SUPERFAMILY SSF52210 129 291 1.7E-47 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 Gene3D G3DSA:3.40.50.261 130 293 9.7E-60 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 SUPERFAMILY SSF51735 1 128 5.74E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 Pfam PF02629 CoA binding domain 6 103 2.1E-26 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_05095 a2c202110de9fdd2520b6864de718cbf 293 PIRSF PIRSF001553 1 293 8.9E-116 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_07680 ba44c1adf5f3fc9633bc6517baf36b70 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.0E-35 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07680 ba44c1adf5f3fc9633bc6517baf36b70 104 SUPERFAMILY SSF141091 1 100 3.14E-33 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07680 ba44c1adf5f3fc9633bc6517baf36b70 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_07680 ba44c1adf5f3fc9633bc6517baf36b70 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 1.2E-27 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07680 ba44c1adf5f3fc9633bc6517baf36b70 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 23.01 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 Pfam PF08402 TOBE domain 282 348 3.0E-10 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 Gene3D G3DSA:2.40.50.100 240 350 2.3E-8 T 12-10-2018 AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 Gene3D G3DSA:2.40.50.140 296 339 2.3E-8 T 12-10-2018 AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 SUPERFAMILY SSF50331 240 352 1.8E-16 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 Gene3D G3DSA:3.40.50.300 1 238 6.3E-77 T 12-10-2018 AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 Pfam PF00005 ABC transporter 22 163 7.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 SUPERFAMILY SSF52540 6 243 3.06E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_20525 840a6e99fe7db120c95c0d63a8a2c226 353 SMART SM00382 30 221 1.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01750 9414944c4c8f2f3350378490797f40da 317 TIGRFAM TIGR00688 rarD: protein RarD 6 254 4.0E-57 T 12-10-2018 IPR004626 RarD protein GO:0005887 AFR_01750 9414944c4c8f2f3350378490797f40da 317 SUPERFAMILY SSF103481 184 285 2.35E-7 T 12-10-2018 AFR_01750 9414944c4c8f2f3350378490797f40da 317 Pfam PF00892 EamA-like transporter family 6 142 1.1E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_01750 9414944c4c8f2f3350378490797f40da 317 SUPERFAMILY SSF103481 47 143 5.49E-10 T 12-10-2018 AFR_27950 a6b79f3d03a5a0581919f0143bd5c545 430 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 430 164.873 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFR_27950 a6b79f3d03a5a0581919f0143bd5c545 430 Gene3D G3DSA:3.90.1150.110 33 415 6.4E-109 T 12-10-2018 AFR_27950 a6b79f3d03a5a0581919f0143bd5c545 430 Pfam PF12390 Selenocysteine synthase N terminal 9 48 3.2E-7 T 12-10-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFR_27950 a6b79f3d03a5a0581919f0143bd5c545 430 SUPERFAMILY SSF53383 72 375 1.55E-30 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_27950 a6b79f3d03a5a0581919f0143bd5c545 430 Pfam PF03841 L-seryl-tRNA selenium transferase 75 412 1.5E-95 T 12-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFR_27950 a6b79f3d03a5a0581919f0143bd5c545 430 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 10 425 7.7E-122 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFR_27950 a6b79f3d03a5a0581919f0143bd5c545 430 Gene3D G3DSA:3.40.640.10 87 337 6.4E-109 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 PRINTS PR00132 Glycosyl hydrolase family 2 signature 547 562 1.7E-28 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 PRINTS PR00132 Glycosyl hydrolase family 2 signature 474 489 1.7E-28 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 PRINTS PR00132 Glycosyl hydrolase family 2 signature 181 196 1.7E-28 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 PRINTS PR00132 Glycosyl hydrolase family 2 signature 400 418 1.7E-28 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 PRINTS PR00132 Glycosyl hydrolase family 2 signature 369 383 1.7E-28 T 12-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Gene3D G3DSA:2.60.120.1060 1355 1498 1.6E-47 T 12-10-2018 IPR038637 NPCBM domain superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SUPERFAMILY SSF49899 601 782 1.27E-26 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 84 251 1.4E-40 T 12-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SMART SM01038 951 1226 1.6E-61 T 12-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SUPERFAMILY SSF49303 255 358 9.78E-23 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Pfam PF00703 Glycosyl hydrolases family 2 255 358 4.9E-14 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 360 592 7.2E-68 T 12-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Gene3D G3DSA:2.60.120.260 37 254 1.1E-71 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Pfam PF02929 Beta galactosidase small chain 953 1224 7.0E-52 T 12-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Gene3D G3DSA:3.20.20.80 359 602 2.0E-80 T 12-10-2018 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Gene3D G3DSA:2.60.40.10 255 358 4.6E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 1260 1333 7.4E-9 T 12-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SUPERFAMILY SSF51445 360 594 2.72E-68 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SUPERFAMILY SSF74650 937 1228 1.4E-55 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SUPERFAMILY SSF49785 42 253 1.82E-57 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SMART SM00560 645 778 9.0E-20 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 630 780 3.7E-21 T 12-10-2018 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SUPERFAMILY SSF49303 833 926 6.55E-5 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Gene3D G3DSA:2.70.98.10 957 1230 1.3E-62 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SMART SM00776 1354 1499 1.7E-61 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Gene3D G3DSA:2.60.120.200 603 783 2.4E-23 T 12-10-2018 AFR_24760 bbca863a2a460491116a913dc09316a9 1500 SUPERFAMILY SSF49785 1357 1497 6.38E-45 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_24760 bbca863a2a460491116a913dc09316a9 1500 Pfam PF08305 NPCBM/NEW2 domain 1357 1497 1.6E-47 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module AFR_25805 192f7503d3489852547e7f8c7b138c9e 263 SUPERFAMILY SSF51126 49 221 2.92E-53 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_25805 192f7503d3489852547e7f8c7b138c9e 263 Gene3D G3DSA:2.160.20.10 45 263 6.1E-76 T 12-10-2018 IPR012334 Pectin lyase fold AFR_25805 192f7503d3489852547e7f8c7b138c9e 263 Pfam PF03211 Pectate lyase 39 236 3.1E-83 T 12-10-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 PRINTS PR00340 P-II protein signature 2 17 1.8E-37 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 PRINTS PR00340 P-II protein signature 83 103 1.8E-37 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 PRINTS PR00340 P-II protein signature 52 75 1.8E-37 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 PRINTS PR00340 P-II protein signature 23 41 1.8E-37 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.1E-39 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 SUPERFAMILY SSF54913 1 112 4.77E-42 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 Gene3D G3DSA:3.30.70.120 1 112 3.3E-44 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 SMART SM00938 4 105 4.8E-57 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFR_36420 abd816ade178dcd232ec7c32dacf82d1 112 PIRSF PIRSF039144 1 112 5.5E-50 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFR_12645 b42da6db3845f2ed70120f7af4fae91f 208 Gene3D G3DSA:3.40.430.10 1 208 6.9E-38 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_12645 b42da6db3845f2ed70120f7af4fae91f 208 Pfam PF01872 RibD C-terminal domain 2 182 2.1E-14 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_12645 b42da6db3845f2ed70120f7af4fae91f 208 SUPERFAMILY SSF53597 3 205 8.03E-20 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_09930 905582bada802428c7e6a16e516e4a5b 349 PIRSF PIRSF002849 13 326 1.2E-125 T 12-10-2018 AFR_09930 905582bada802428c7e6a16e516e4a5b 349 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 52 181 4.3E-64 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_09930 905582bada802428c7e6a16e516e4a5b 349 Gene3D G3DSA:1.10.8.300 213 321 2.6E-29 T 12-10-2018 AFR_09930 905582bada802428c7e6a16e516e4a5b 349 SUPERFAMILY SSF52540 36 296 4.14E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09930 905582bada802428c7e6a16e516e4a5b 349 Gene3D G3DSA:3.40.50.300 33 198 1.4E-44 T 12-10-2018 AFR_10645 6735ae15ac9008bd2d6e51306abf5181 321 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 37 320 19.596 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFR_10645 6735ae15ac9008bd2d6e51306abf5181 321 Gene3D G3DSA:1.10.357.140 49 202 1.6E-19 T 12-10-2018 AFR_10645 6735ae15ac9008bd2d6e51306abf5181 321 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 39 318 5.4E-95 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFR_10645 6735ae15ac9008bd2d6e51306abf5181 321 Pfam PF01040 UbiA prenyltransferase family 53 304 2.8E-68 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFR_30365 8674bb8493ce9eb1446a38bdf33e1759 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 432 4.0E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_30365 8674bb8493ce9eb1446a38bdf33e1759 433 Pfam PF13796 Putative sensor 18 191 3.1E-30 T 12-10-2018 IPR025828 Putative sensor domain AFR_30365 8674bb8493ce9eb1446a38bdf33e1759 433 SMART SM00387 314 433 5.3E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_30365 8674bb8493ce9eb1446a38bdf33e1759 433 Gene3D G3DSA:3.30.565.10 282 431 2.1E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30365 8674bb8493ce9eb1446a38bdf33e1759 433 Pfam PF07730 Histidine kinase 219 282 1.7E-9 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_30365 8674bb8493ce9eb1446a38bdf33e1759 433 SUPERFAMILY SSF55874 291 431 1.06E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 Pfam PF00361 Proton-conducting membrane transporter 148 435 3.6E-84 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 432 454 7.0E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 52 71 7.0E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 509 530 7.0E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 276 298 7.0E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 98 118 7.0E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 124 144 2.2E-65 T 12-10-2018 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 326 338 2.2E-65 T 12-10-2018 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 171 192 2.2E-65 T 12-10-2018 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 258 284 2.2E-65 T 12-10-2018 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 433 452 2.2E-65 T 12-10-2018 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 96 121 2.2E-65 T 12-10-2018 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 257 2.2E-65 T 12-10-2018 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 78 135 1.9E-22 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01710 680cfd7b662dfc8b2fa4876f8aca1a59 641 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 17 632 1.6E-213 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_18730 967d830240952269a3ac343b9813c142 475 SUPERFAMILY SSF51905 5 389 1.57E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18730 967d830240952269a3ac343b9813c142 475 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 57 4.7E-8 T 12-10-2018 AFR_18730 967d830240952269a3ac343b9813c142 475 Gene3D G3DSA:3.50.50.60 1 268 2.4E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18730 967d830240952269a3ac343b9813c142 475 Gene3D G3DSA:3.50.50.60 315 420 3.6E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18730 967d830240952269a3ac343b9813c142 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 1.2E-5 T 12-10-2018 AFR_18730 967d830240952269a3ac343b9813c142 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.2E-5 T 12-10-2018 AFR_18730 967d830240952269a3ac343b9813c142 475 Pfam PF00743 Flavin-binding monooxygenase-like 77 205 5.1E-8 T 12-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_10730 6e5f1983eaa671f0b2c344e58fd23237 248 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 19 136 3.1E-15 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_10730 6e5f1983eaa671f0b2c344e58fd23237 248 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 223 2.6E-20 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_10730 6e5f1983eaa671f0b2c344e58fd23237 248 Gene3D G3DSA:1.20.120.450 4 139 8.6E-6 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_10730 6e5f1983eaa671f0b2c344e58fd23237 248 Pfam PF07398 MDMPI C-terminal domain 150 239 1.1E-12 T 12-10-2018 IPR010872 MDMPI C-terminal AFR_10730 6e5f1983eaa671f0b2c344e58fd23237 248 SUPERFAMILY SSF109854 4 137 1.28E-11 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_18640 cef8abd8222f3d0f01ed003b6ad5d28c 369 SUPERFAMILY SSF53686 7 367 6.42E-74 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_18640 cef8abd8222f3d0f01ed003b6ad5d28c 369 Gene3D G3DSA:3.40.50.1100 92 186 4.4E-93 T 12-10-2018 AFR_18640 cef8abd8222f3d0f01ed003b6ad5d28c 369 Gene3D G3DSA:3.40.50.1100 47 361 4.4E-93 T 12-10-2018 AFR_18640 cef8abd8222f3d0f01ed003b6ad5d28c 369 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 356 1.3E-58 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_20095 7268f445e3e6667a38d28547159d5fef 178 SUPERFAMILY SSF47413 2 67 9.57E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_20095 7268f445e3e6667a38d28547159d5fef 178 SUPERFAMILY SSF51182 45 174 3.06E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_20095 7268f445e3e6667a38d28547159d5fef 178 Pfam PF13560 Helix-turn-helix domain 1 57 1.7E-12 T 12-10-2018 AFR_20095 7268f445e3e6667a38d28547159d5fef 178 SMART SM00530 4 59 3.7E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_20095 7268f445e3e6667a38d28547159d5fef 178 Gene3D G3DSA:1.10.260.40 1 65 1.2E-14 T 12-10-2018 AFR_20095 7268f445e3e6667a38d28547159d5fef 178 Gene3D G3DSA:2.60.120.10 66 177 1.9E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_20095 7268f445e3e6667a38d28547159d5fef 178 Pfam PF07883 Cupin domain 106 174 2.0E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2558 2964 2.6E-124 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 480 869 3.7E-125 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1514 1913 2.2E-133 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.30 1222 1467 6.1E-131 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.40.50.12780 1480 1883 1.5E-143 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.40.50.12780 446 839 3.1E-130 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.40.50.12780 2525 2934 3.3E-132 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.30 3296 3580 5.5E-80 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2019 2034 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF56801 1482 2008 6.02E-151 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF47336 1989 2057 6.94E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 2268 2511 1.05E-56 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00668 Condensation domain 8 437 1.4E-77 T 12-10-2018 IPR001242 Condensation domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00668 Condensation domain 2091 2515 2.4E-67 T 12-10-2018 IPR001242 Condensation domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00668 Condensation domain 3135 3578 9.6E-36 T 12-10-2018 IPR001242 Condensation domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00668 Condensation domain 1046 1469 1.0E-68 T 12-10-2018 IPR001242 Condensation domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.10 13 371 5.5E-138 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF56801 2530 3058 1.02E-139 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SMART SM00823 Phosphopantetheine attachment site 1995 2063 2.5E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SMART SM00823 Phosphopantetheine attachment site 948 1016 6.3E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SMART SM00823 Phosphopantetheine attachment site 3045 3113 7.8E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 1044 1235 3.67E-40 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.300.30 2935 3030 1.5E-31 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:1.10.1200.10 1983 2065 1.5E-23 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:1.10.1200.10 934 1016 1.7E-24 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:1.10.1200.10 3031 3115 1.3E-21 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.10 2096 2452 1.1E-126 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF13193 AMP-binding enzyme C-terminal domain 853 923 2.5E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF13193 AMP-binding enzyme C-terminal domain 1897 1970 1.7E-5 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF13193 AMP-binding enzyme C-terminal domain 2948 3020 3.3E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3447 3579 5.2E-28 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.10 1051 1404 6.1E-131 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00501 AMP-binding enzyme 1494 1889 3.1E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00501 AMP-binding enzyme 460 845 5.6E-89 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00501 AMP-binding enzyme 2537 2940 9.0E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF47336 3038 3107 3.4E-15 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF56801 420 961 8.11E-145 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 3122 3300 2.67E-31 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2680 2691 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.300.30 840 933 1.1E-31 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.300.30 1884 1982 2.4E-29 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 3314 3578 3.22E-30 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 192 428 6.12E-54 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3069 3084 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.30 188 436 5.5E-138 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 2089 2283 1.67E-33 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1632 1643 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 ProSitePatterns PS00012 Phosphopantetheine attachment site. 972 987 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.10 3116 3292 1.2E-42 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF47336 941 1010 2.62E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 1226 1460 4.0E-56 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Gene3D G3DSA:3.30.559.30 2269 2517 1.1E-126 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00550 Phosphopantetheine attachment site 3048 3107 2.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00550 Phosphopantetheine attachment site 1997 2058 6.9E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 Pfam PF00550 Phosphopantetheine attachment site 950 1010 1.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 SUPERFAMILY SSF52777 6 202 1.89E-40 T 12-10-2018 AFR_23670 ac0d8e1689e3583681b435b071de482e 3581 ProSitePatterns PS00455 Putative AMP-binding domain signature. 595 606 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_24815 904a6963409bdb97463a516f9fb4c1c9 470 SUPERFAMILY SSF55073 317 466 1.46E-38 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_24815 904a6963409bdb97463a516f9fb4c1c9 470 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 466 2.4E-35 T 12-10-2018 IPR000160 GGDEF domain AFR_24815 904a6963409bdb97463a516f9fb4c1c9 470 Gene3D G3DSA:3.30.70.270 306 470 5.6E-49 T 12-10-2018 AFR_24815 904a6963409bdb97463a516f9fb4c1c9 470 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 466 5.2E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_24815 904a6963409bdb97463a516f9fb4c1c9 470 SMART SM00267 301 470 2.3E-52 T 12-10-2018 IPR000160 GGDEF domain AFR_15485 e184a2a81a1617001b49556f3057753c 1079 Gene3D G3DSA:1.20.1050.60 528 621 3.0E-256 T 12-10-2018 AFR_15485 e184a2a81a1617001b49556f3057753c 1079 Pfam PF07971 Glycosyl hydrolase family 92 415 917 2.7E-154 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_15485 e184a2a81a1617001b49556f3057753c 1079 SUPERFAMILY SSF48208 440 915 8.16E-22 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_15485 e184a2a81a1617001b49556f3057753c 1079 Gene3D G3DSA:3.30.2080.10 474 921 3.0E-256 T 12-10-2018 AFR_15485 e184a2a81a1617001b49556f3057753c 1079 Gene3D G3DSA:2.70.98.10 221 527 3.0E-256 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_15485 e184a2a81a1617001b49556f3057753c 1079 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 218 920 2.7E-161 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_15485 e184a2a81a1617001b49556f3057753c 1079 Gene3D G3DSA:1.20.1610.10 622 790 3.0E-256 T 12-10-2018 AFR_15485 e184a2a81a1617001b49556f3057753c 1079 SUPERFAMILY SSF49785 947 1079 7.17E-11 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15485 e184a2a81a1617001b49556f3057753c 1079 Gene3D G3DSA:2.60.120.260 945 1079 1.4E-14 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_18945 2b5d69259c61952b5d672854829a9c09 507 Pfam PF00005 ABC transporter 280 431 5.3E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18945 2b5d69259c61952b5d672854829a9c09 507 SMART SM00382 31 219 2.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18945 2b5d69259c61952b5d672854829a9c09 507 SMART SM00382 286 479 9.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18945 2b5d69259c61952b5d672854829a9c09 507 SUPERFAMILY SSF52540 5 229 4.91E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18945 2b5d69259c61952b5d672854829a9c09 507 Gene3D G3DSA:3.40.50.300 2 259 2.6E-56 T 12-10-2018 AFR_18945 2b5d69259c61952b5d672854829a9c09 507 Gene3D G3DSA:3.40.50.300 269 490 1.9E-43 T 12-10-2018 AFR_18945 2b5d69259c61952b5d672854829a9c09 507 Pfam PF00005 ABC transporter 22 171 5.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18945 2b5d69259c61952b5d672854829a9c09 507 SUPERFAMILY SSF52540 274 485 6.1E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18945 2b5d69259c61952b5d672854829a9c09 507 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_01410 60fef73d103eee4cbd47dbea39339356 175 SUPERFAMILY SSF88946 5 80 4.32E-8 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_01410 60fef73d103eee4cbd47dbea39339356 175 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 157 4.7E-43 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_01410 60fef73d103eee4cbd47dbea39339356 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 157 7.6E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_01410 60fef73d103eee4cbd47dbea39339356 175 Pfam PF04542 Sigma-70 region 2 14 75 3.8E-5 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_01410 60fef73d103eee4cbd47dbea39339356 175 Gene3D G3DSA:1.10.10.10 75 160 2.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01410 60fef73d103eee4cbd47dbea39339356 175 SUPERFAMILY SSF88659 97 157 9.53E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_01410 60fef73d103eee4cbd47dbea39339356 175 Pfam PF08281 Sigma-70, region 4 103 153 2.3E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_11395 d55b2aea4d07e191e88145aa3368bb88 428 SUPERFAMILY SSF53850 51 417 3.37E-67 T 12-10-2018 AFR_11395 d55b2aea4d07e191e88145aa3368bb88 428 Gene3D G3DSA:3.40.190.10 69 377 5.8E-75 T 12-10-2018 AFR_11395 d55b2aea4d07e191e88145aa3368bb88 428 Gene3D G3DSA:3.40.190.10 155 399 5.8E-75 T 12-10-2018 AFR_11395 d55b2aea4d07e191e88145aa3368bb88 428 Pfam PF01547 Bacterial extracellular solute-binding protein 83 340 5.4E-26 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_18000 a463e2135859c363e79fde874211f8ef 348 SMART SM00354 8 75 2.4E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18000 a463e2135859c363e79fde874211f8ef 348 Gene3D G3DSA:1.10.260.40 1 60 8.8E-18 T 12-10-2018 AFR_18000 a463e2135859c363e79fde874211f8ef 348 Pfam PF13377 Periplasmic binding protein-like domain 173 334 2.2E-45 T 12-10-2018 AFR_18000 a463e2135859c363e79fde874211f8ef 348 Gene3D G3DSA:3.40.50.2300 165 294 5.4E-76 T 12-10-2018 AFR_18000 a463e2135859c363e79fde874211f8ef 348 Gene3D G3DSA:3.40.50.2300 66 311 5.4E-76 T 12-10-2018 AFR_18000 a463e2135859c363e79fde874211f8ef 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 53 1.9E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18000 a463e2135859c363e79fde874211f8ef 348 SUPERFAMILY SSF53822 65 336 7.46E-84 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_18000 a463e2135859c363e79fde874211f8ef 348 SUPERFAMILY SSF47413 8 55 2.16E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_36050 9876f56ed52e9a9476605e11acc792d2 453 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 256 267 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_36050 9876f56ed52e9a9476605e11acc792d2 453 Gene3D G3DSA:3.40.605.10 4 447 1.9E-165 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_36050 9876f56ed52e9a9476605e11acc792d2 453 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 228 235 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_36050 9876f56ed52e9a9476605e11acc792d2 453 SUPERFAMILY SSF53720 4 449 4.58E-154 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_36050 9876f56ed52e9a9476605e11acc792d2 453 Pfam PF00171 Aldehyde dehydrogenase family 4 447 2.4E-157 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_36050 9876f56ed52e9a9476605e11acc792d2 453 Gene3D G3DSA:3.40.309.10 235 419 1.9E-165 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 SUPERFAMILY SSF54373 212 313 1.45E-23 T 12-10-2018 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 SUPERFAMILY SSF51905 5 396 3.24E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Gene3D G3DSA:3.30.70.1400 476 691 1.0E-102 T 12-10-2018 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Gene3D G3DSA:2.40.30.110 696 773 7.5E-32 T 12-10-2018 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Pfam PF01571 Aminomethyltransferase folate-binding domain 410 677 1.0E-67 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Gene3D G3DSA:3.30.1360.120 402 666 1.0E-102 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 683 773 9.5E-16 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Pfam PF16350 FAD dependent oxidoreductase central domain 353 407 2.3E-16 T 12-10-2018 IPR032503 FAD dependent oxidoreductase, central domain AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Gene3D G3DSA:3.50.50.60 6 369 2.4E-134 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18435 13ffeee1d88ce084339f6e376db55232 786 SUPERFAMILY SSF101790 699 785 1.44E-23 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal AFR_18435 13ffeee1d88ce084339f6e376db55232 786 SUPERFAMILY SSF103025 402 694 1.33E-85 T 12-10-2018 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Pfam PF01266 FAD dependent oxidoreductase 6 350 4.7E-48 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_18435 13ffeee1d88ce084339f6e376db55232 786 Gene3D G3DSA:3.30.9.10 80 313 2.4E-134 T 12-10-2018 AFR_02420 72474fc1738cd67ba041a71bf5014192 169 SUPERFAMILY SSF88946 15 104 4.71E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02420 72474fc1738cd67ba041a71bf5014192 169 Gene3D G3DSA:1.10.10.10 109 169 1.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02420 72474fc1738cd67ba041a71bf5014192 169 Pfam PF08281 Sigma-70, region 4 110 159 5.3E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_02420 72474fc1738cd67ba041a71bf5014192 169 Gene3D G3DSA:1.10.1740.10 7 108 2.2E-9 T 12-10-2018 AFR_02420 72474fc1738cd67ba041a71bf5014192 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 165 1.2E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02420 72474fc1738cd67ba041a71bf5014192 169 SUPERFAMILY SSF88659 109 166 9.72E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_29320 7170c0693631783eea27bca09e0fee98 182 Pfam PF12833 Helix-turn-helix domain 100 178 1.2E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_29320 7170c0693631783eea27bca09e0fee98 182 Gene3D G3DSA:1.10.10.2730 138 179 6.9E-17 T 12-10-2018 AFR_29320 7170c0693631783eea27bca09e0fee98 182 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 146 161 1.0E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_29320 7170c0693631783eea27bca09e0fee98 182 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 161 177 1.0E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_29320 7170c0693631783eea27bca09e0fee98 182 SUPERFAMILY SSF46689 76 127 9.19E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29320 7170c0693631783eea27bca09e0fee98 182 SMART SM00342 94 177 5.1E-31 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_29320 7170c0693631783eea27bca09e0fee98 182 SUPERFAMILY SSF46689 130 179 4.93E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29320 7170c0693631783eea27bca09e0fee98 182 Gene3D G3DSA:1.10.10.60 75 137 3.3E-14 T 12-10-2018 AFR_36275 40621c76b371f3670d591710c4705cec 395 Pfam PF00266 Aminotransferase class-V 63 306 2.6E-21 T 12-10-2018 IPR000192 Aminotransferase class V domain AFR_36275 40621c76b371f3670d591710c4705cec 395 Gene3D G3DSA:3.90.1150.10 23 383 2.9E-63 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_36275 40621c76b371f3670d591710c4705cec 395 SUPERFAMILY SSF53383 22 391 4.03E-61 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_36275 40621c76b371f3670d591710c4705cec 395 Gene3D G3DSA:3.40.640.10 35 287 2.9E-63 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1945 1960 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SMART SM00823 Phosphopantetheine attachment site 1921 1990 9.4E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SMART SM00823 Phosphopantetheine attachment site 2914 2982 1.4E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SMART SM00823 Phosphopantetheine attachment site 921 990 1.5E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.10 2004 2356 9.7E-143 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1585 1596 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF56801 2414 2927 2.22E-123 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00668 Condensation domain 2996 3429 1.5E-47 T 12-10-2018 IPR001242 Condensation domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00668 Condensation domain 2003 2429 3.7E-73 T 12-10-2018 IPR001242 Condensation domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00668 Condensation domain 9 433 3.2E-71 T 12-10-2018 IPR001242 Condensation domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00668 Condensation domain 1002 1435 1.6E-86 T 12-10-2018 IPR001242 Condensation domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.10 1004 1366 3.8E-152 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.30 1178 1421 3.8E-152 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.40.50.980 2465 2593 1.7E-83 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 2005 2164 3.45E-44 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.10 2984 3148 1.3E-39 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 1178 1420 2.67E-60 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 6 194 9.0E-40 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 3166 3420 1.89E-38 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 ProSitePatterns PS00455 Putative AMP-binding domain signature. 585 596 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 998 1192 8.34E-44 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 179 440 5.78E-57 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2578 2589 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.40.50.980 2454 2729 1.7E-83 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.30 2168 2411 9.7E-143 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.30 3149 3423 1.7E-88 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF56801 411 934 4.84E-128 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2938 2953 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF47336 2908 2975 1.44E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3288 3443 1.0E-42 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00550 Phosphopantetheine attachment site 922 983 3.3E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00550 Phosphopantetheine attachment site 1922 1982 1.4E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00550 Phosphopantetheine attachment site 2915 2975 7.4E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 473 847 1.6E-105 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2464 2841 1.4E-109 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1472 1848 1.4E-102 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 ProSitePatterns PS00012 Phosphopantetheine attachment site. 945 960 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF47336 916 986 3.27E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:1.10.1200.10 910 991 3.0E-26 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:1.10.1200.10 1910 1992 1.1E-26 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.30 180 429 1.2E-126 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.40.50.12780 440 825 2.1E-116 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.40.50.12780 1441 1825 3.9E-113 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.300.30 1826 1909 2.7E-18 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.300.30 826 909 5.9E-19 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.300.30 2819 2900 2.4E-18 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF47336 1915 1986 2.09E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00501 AMP-binding enzyme 1451 1831 1.8E-72 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00501 AMP-binding enzyme 452 831 4.0E-78 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Pfam PF00501 AMP-binding enzyme 2453 2824 1.6E-77 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF56801 1418 1934 3.53E-121 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 2993 3178 8.89E-30 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:2.30.38.10 2741 2818 3.0E-30 T 12-10-2018 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:3.30.559.10 13 364 1.2E-126 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 Gene3D G3DSA:1.10.1200.10 2901 2983 7.9E-25 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23675 eea981a9316c41f1eb70c9d3adeb12e3 3458 SUPERFAMILY SSF52777 2169 2417 8.56E-57 T 12-10-2018 AFR_39410 bcede6249b47386cbf67428478597b40 527 Gene3D G3DSA:3.40.50.11290 214 311 2.8E-40 T 12-10-2018 AFR_39410 bcede6249b47386cbf67428478597b40 527 PIRSF PIRSF005522 1 479 2.6E-201 T 12-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 AFR_39410 bcede6249b47386cbf67428478597b40 527 Gene3D G3DSA:3.30.1490.270 348 407 7.6E-18 T 12-10-2018 AFR_39410 bcede6249b47386cbf67428478597b40 527 Pfam PF14403 Circularly permuted ATP-grasp type 2 76 452 8.6E-154 T 12-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 AFR_39410 bcede6249b47386cbf67428478597b40 527 SUPERFAMILY SSF56059 42 466 4.95E-49 T 12-10-2018 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 SUPERFAMILY SSF52156 800 929 7.59E-34 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 PRINTS PR00315 GTP-binding elongation factor signature 620 629 8.4E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 PRINTS PR00315 GTP-binding elongation factor signature 568 578 8.4E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 PRINTS PR00315 GTP-binding elongation factor signature 516 529 8.4E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 PRINTS PR00315 GTP-binding elongation factor signature 584 595 8.4E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Pfam PF11987 Translation-initiation factor 2 804 912 2.8E-34 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 SUPERFAMILY SSF50447 690 771 6.83E-23 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 3 52 5.5E-14 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Gene3D G3DSA:3.40.50.300 509 687 1.0E-67 T 12-10-2018 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 515 675 6.5E-31 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Gene3D G3DSA:3.40.50.10050 812 923 7.0E-34 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 SUPERFAMILY SSF50447 923 1021 3.74E-26 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 SUPERFAMILY SSF52540 513 679 1.05E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Pfam PF00009 Elongation factor Tu GTP binding domain 517 677 2.4E-33 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 426 1021 8.1E-226 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Gene3D G3DSA:2.40.30.10 688 807 4.9E-37 T 12-10-2018 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 1021 16.78 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Gene3D G3DSA:2.40.30.10 924 1022 3.6E-28 T 12-10-2018 AFR_35975 3543964d405bd79cd1e8ec348be37b75 1022 Gene3D G3DSA:1.10.10.2480 3 63 6.0E-14 T 12-10-2018 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 Gene3D G3DSA:3.90.420.10 64 291 5.3E-68 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 318 400 2.3E-7 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 SUPERFAMILY SSF56524 68 293 7.06E-60 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 Gene3D G3DSA:2.60.40.650 300 412 2.4E-24 T 12-10-2018 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 SUPERFAMILY SSF81296 310 410 7.0E-22 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 224 240 3.7E-21 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 241 254 3.7E-21 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 169 184 3.7E-21 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 335 347 3.7E-21 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 87 103 3.7E-21 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 PRINTS PR00407 Eukaryotic molybdopterin domain signature 257 270 3.7E-21 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFR_20060 7338c335d932c5c01449e28c82ccb1c8 412 Pfam PF00174 Oxidoreductase molybdopterin binding domain 99 278 7.7E-50 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFR_03310 8f5c25221910f7376821529694c20ab0 816 SMART SM00388 597 665 1.3E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_03310 8f5c25221910f7376821529694c20ab0 816 Pfam PF00512 His Kinase A (phospho-acceptor) domain 598 665 2.4E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_03310 8f5c25221910f7376821529694c20ab0 816 SMART SM00387 707 816 3.1E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03310 8f5c25221910f7376821529694c20ab0 816 Gene3D G3DSA:1.10.287.130 590 669 1.4E-16 T 12-10-2018 AFR_03310 8f5c25221910f7376821529694c20ab0 816 Gene3D G3DSA:1.20.120.620 370 471 4.5E-15 T 12-10-2018 IPR038318 KdpD, transmembrane domain superfamily AFR_03310 8f5c25221910f7376821529694c20ab0 816 Gene3D G3DSA:3.40.50.300 1 203 6.6E-90 T 12-10-2018 AFR_03310 8f5c25221910f7376821529694c20ab0 816 SUPERFAMILY SSF47384 588 665 1.59E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_03310 8f5c25221910f7376821529694c20ab0 816 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 204 1.2E-89 T 12-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 AFR_03310 8f5c25221910f7376821529694c20ab0 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 744 758 9.2E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03310 8f5c25221910f7376821529694c20ab0 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 777 795 9.2E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03310 8f5c25221910f7376821529694c20ab0 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 801 814 9.2E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03310 8f5c25221910f7376821529694c20ab0 816 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 708 815 3.9E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03310 8f5c25221910f7376821529694c20ab0 816 Pfam PF00582 Universal stress protein family 224 331 4.8E-7 T 12-10-2018 IPR006016 UspA AFR_03310 8f5c25221910f7376821529694c20ab0 816 Gene3D G3DSA:3.30.565.10 673 816 2.4E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03310 8f5c25221910f7376821529694c20ab0 816 Pfam PF13493 Domain of unknown function (DUF4118) 375 478 1.0E-26 T 12-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain AFR_03310 8f5c25221910f7376821529694c20ab0 816 SUPERFAMILY SSF52402 225 348 5.98E-11 T 12-10-2018 AFR_03310 8f5c25221910f7376821529694c20ab0 816 Gene3D G3DSA:3.40.50.620 210 347 2.8E-8 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_03310 8f5c25221910f7376821529694c20ab0 816 SUPERFAMILY SSF55874 655 814 1.7E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_39315 b068412fee1b95eaba9670508e076092 286 Pfam PF03099 Biotin/lipoate A/B protein ligase family 55 170 1.0E-6 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFR_39315 b068412fee1b95eaba9670508e076092 286 SUPERFAMILY SSF55681 24 219 1.62E-41 T 12-10-2018 AFR_39315 b068412fee1b95eaba9670508e076092 286 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 33 284 4.5E-41 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_39315 b068412fee1b95eaba9670508e076092 286 Gene3D G3DSA:3.30.930.10 4 235 7.6E-63 T 12-10-2018 AFR_39315 b068412fee1b95eaba9670508e076092 286 Pfam PF02237 Biotin protein ligase C terminal domain 239 284 1.2E-8 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_39315 b068412fee1b95eaba9670508e076092 286 SUPERFAMILY SSF50037 240 284 3.94E-5 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal AFR_39315 b068412fee1b95eaba9670508e076092 286 Gene3D G3DSA:2.30.30.100 239 286 2.1E-14 T 12-10-2018 AFR_40185 3cbf2176ab18ee729970612d1f583356 246 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 17 225 34.377 T 12-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 AFR_40185 3cbf2176ab18ee729970612d1f583356 246 Gene3D G3DSA:1.10.10.10 21 92 6.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40185 3cbf2176ab18ee729970612d1f583356 246 Pfam PF02629 CoA binding domain 98 194 5.7E-21 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_40185 3cbf2176ab18ee729970612d1f583356 246 SUPERFAMILY SSF46785 23 95 2.18E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_40185 3cbf2176ab18ee729970612d1f583356 246 SUPERFAMILY SSF51735 98 220 9.84E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40185 3cbf2176ab18ee729970612d1f583356 246 Pfam PF06971 Putative DNA-binding protein N-terminus 22 69 1.4E-18 T 12-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 AFR_40185 3cbf2176ab18ee729970612d1f583356 246 SMART SM00881 95 196 4.8E-19 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_40185 3cbf2176ab18ee729970612d1f583356 246 Gene3D G3DSA:3.40.50.720 93 224 4.9E-45 T 12-10-2018 AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 SMART SM00382 426 624 7.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 SUPERFAMILY SSF52540 364 663 2.44E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 53 176 8.8E-13 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 Pfam PF09397 Ftsk gamma domain 696 753 7.8E-23 T 12-10-2018 IPR018541 FtsK gamma domain AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 SMART SM00843 691 756 9.4E-30 T 12-10-2018 IPR018541 FtsK gamma domain AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 Pfam PF01580 FtsK/SpoIIIE family 391 526 3.2E-41 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 Pfam PF01580 FtsK/SpoIIIE family 538 591 2.8E-15 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 Gene3D G3DSA:1.10.10.10 688 752 1.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 Gene3D G3DSA:3.40.50.300 388 677 3.7E-103 T 12-10-2018 AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 Gene3D G3DSA:3.30.980.40 285 387 5.9E-27 T 12-10-2018 AFR_35820 704afbf2e88b0f12c358faaf8c0f059a 768 SUPERFAMILY SSF46785 693 758 1.63E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10925 07176cb0f532fba5d96786a26e7e62fd 247 SUPERFAMILY SSF46894 124 222 3.68E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_10925 07176cb0f532fba5d96786a26e7e62fd 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 2.3E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_10925 07176cb0f532fba5d96786a26e7e62fd 247 Gene3D G3DSA:1.10.10.10 120 225 6.0E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10925 07176cb0f532fba5d96786a26e7e62fd 247 SMART SM00862 147 221 5.7E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_10925 07176cb0f532fba5d96786a26e7e62fd 247 Gene3D G3DSA:3.40.50.2300 1 119 3.2E-35 T 12-10-2018 AFR_10925 07176cb0f532fba5d96786a26e7e62fd 247 SUPERFAMILY SSF52172 30 116 1.28E-5 T 12-10-2018 IPR011006 CheY-like superfamily AFR_02640 f26c75837465ae08a2ae78acfa230c45 89 SMART SM00530 12 71 4.6E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_02640 f26c75837465ae08a2ae78acfa230c45 89 SUPERFAMILY SSF47413 8 62 6.7E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_02640 f26c75837465ae08a2ae78acfa230c45 89 Gene3D G3DSA:1.10.260.40 4 73 8.6E-12 T 12-10-2018 AFR_02640 f26c75837465ae08a2ae78acfa230c45 89 Pfam PF13560 Helix-turn-helix domain 8 69 8.7E-12 T 12-10-2018 AFR_03900 3b49cc6dc4867c8ab3f848ef55bba4fc 227 SUPERFAMILY SSF53335 22 207 5.43E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_03900 3b49cc6dc4867c8ab3f848ef55bba4fc 227 Gene3D G3DSA:3.40.50.150 19 211 2.6E-49 T 12-10-2018 AFR_03900 3b49cc6dc4867c8ab3f848ef55bba4fc 227 Pfam PF13649 Methyltransferase domain 65 155 1.8E-19 T 12-10-2018 AFR_14245 cd9e92271a90c47d48b42635eb2c20a3 451 Pfam PF12323 Helix-turn-helix domain 2 37 2.3E-6 T 12-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFR_14245 cd9e92271a90c47d48b42635eb2c20a3 451 Pfam PF07282 Putative transposase DNA-binding domain 327 395 2.3E-20 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_14245 cd9e92271a90c47d48b42635eb2c20a3 451 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 282 354 3.4E-9 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_14245 cd9e92271a90c47d48b42635eb2c20a3 451 Pfam PF01385 Probable transposase 193 313 5.9E-20 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFR_11715 a6f55bada6a122ad0345061615a4d872 375 Gene3D G3DSA:3.40.640.10 1 251 3.9E-81 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_11715 a6f55bada6a122ad0345061615a4d872 375 PIRSF PIRSF000390 1 374 1.6E-99 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_11715 a6f55bada6a122ad0345061615a4d872 375 Gene3D G3DSA:3.90.1150.10 252 374 3.1E-33 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_11715 a6f55bada6a122ad0345061615a4d872 375 SUPERFAMILY SSF53383 5 373 6.05E-98 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_11715 a6f55bada6a122ad0345061615a4d872 375 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 372 5.0E-102 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_22070 461ed9527cc566c73535126ff0d5e973 258 Pfam PF01061 ABC-2 type transporter 13 223 2.6E-25 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_22070 461ed9527cc566c73535126ff0d5e973 258 PIRSF PIRSF006648 2 258 2.9E-67 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 ProSitePatterns PS00622 LuxR-type HTH domain signature. 848 875 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 Gene3D G3DSA:1.10.10.10 785 891 4.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11935 26aed1d16383d460fd57d0950b533de5 891 SMART SM00421 831 888 3.7E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 Gene3D G3DSA:3.40.50.300 5 169 4.3E-7 T 12-10-2018 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 SUPERFAMILY SSF46894 825 886 6.46E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 Pfam PF00196 Bacterial regulatory proteins, luxR family 833 885 3.5E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 848 864 1.8E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 834 848 1.8E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 864 876 1.8E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 Pfam PF13191 AAA ATPase domain 5 153 2.4E-19 T 12-10-2018 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 SUPERFAMILY SSF48452 527 685 1.33E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_11935 26aed1d16383d460fd57d0950b533de5 891 SUPERFAMILY SSF52540 4 201 1.67E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27320 99f8f427c019ea4563ea4e71d57ab7a7 188 SUPERFAMILY SSF48498 84 185 1.75E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_27320 99f8f427c019ea4563ea4e71d57ab7a7 188 SUPERFAMILY SSF46689 6 82 7.98E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_27320 99f8f427c019ea4563ea4e71d57ab7a7 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27320 99f8f427c019ea4563ea4e71d57ab7a7 188 Gene3D G3DSA:1.10.357.10 2 188 1.4E-47 T 12-10-2018 AFR_27320 99f8f427c019ea4563ea4e71d57ab7a7 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27320 99f8f427c019ea4563ea4e71d57ab7a7 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SUPERFAMILY SSF47384 317 388 2.16E-8 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 526 1.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 545 1.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 493 1.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 507 1.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Gene3D G3DSA:3.30.565.10 391 556 1.1E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32450 9785ebae3198152b62e5000052cf47e5 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 187 308 1.9E-16 T 12-10-2018 IPR000014 PAS domain AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Pfam PF00072 Response regulator receiver domain 565 675 1.6E-18 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Pfam PF08448 PAS fold 197 303 1.7E-14 T 12-10-2018 IPR013656 PAS fold-4 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SUPERFAMILY SSF52172 564 681 5.41E-25 T 12-10-2018 IPR011006 CheY-like superfamily AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Gene3D G3DSA:3.40.50.2300 563 682 8.1E-25 T 12-10-2018 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SMART SM00091 191 257 3.5E-7 T 12-10-2018 IPR000014 PAS domain AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Gene3D G3DSA:3.30.450.20 182 302 1.4E-21 T 12-10-2018 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Gene3D G3DSA:3.30.450.40 10 181 4.2E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SUPERFAMILY SSF55781 31 190 2.18E-10 T 12-10-2018 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 546 3.6E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Pfam PF00512 His Kinase A (phospho-acceptor) domain 322 387 3.0E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SUPERFAMILY SSF55874 379 546 8.64E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SMART SM00448 563 675 1.1E-18 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SMART SM00387 429 548 1.2E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Gene3D G3DSA:1.10.287.130 314 386 9.5E-14 T 12-10-2018 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 Pfam PF01590 GAF domain 88 177 5.3E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SMART SM00388 322 388 3.2E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_32450 9785ebae3198152b62e5000052cf47e5 690 SUPERFAMILY SSF55785 181 302 1.29E-22 T 12-10-2018 IPR035965 PAS domain superfamily AFR_00720 5db4c3121acb7716d3fb6c46571bb038 237 SMART SM01211 3 222 8.9E-116 T 12-10-2018 AFR_00720 5db4c3121acb7716d3fb6c46571bb038 237 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 207 2.7E-33 T 12-10-2018 AFR_00720 5db4c3121acb7716d3fb6c46571bb038 237 SUPERFAMILY SSF52317 2 220 8.06E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_00720 5db4c3121acb7716d3fb6c46571bb038 237 PIRSF PIRSF001586 1 225 2.9E-75 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_00720 5db4c3121acb7716d3fb6c46571bb038 237 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 3 220 5.7E-73 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_00720 5db4c3121acb7716d3fb6c46571bb038 237 Gene3D G3DSA:3.40.50.880 2 223 5.1E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_00720 5db4c3121acb7716d3fb6c46571bb038 237 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 220 37.212 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 Gene3D G3DSA:2.40.50.100 2 97 6.9E-21 T 12-10-2018 AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 Gene3D G3DSA:3.30.559.10 232 469 4.1E-67 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 Pfam PF02817 e3 binding domain 134 166 6.0E-13 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 SUPERFAMILY SSF52777 240 466 1.96E-64 T 12-10-2018 AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 SUPERFAMILY SSF47005 128 170 3.92E-10 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 SUPERFAMILY SSF51230 5 79 3.53E-22 T 12-10-2018 IPR011053 Single hybrid motif AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 Pfam PF00364 Biotin-requiring enzyme 6 76 2.1E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 248 467 5.7E-64 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFR_16930 b5e654adef2bfbd276cc8d82dff9c80a 471 Gene3D G3DSA:4.10.320.10 121 172 1.3E-13 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFR_37675 394b9e1777ce24e6ab08d28ac37d53af 557 SUPERFAMILY SSF103473 55 534 1.31E-61 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_37675 394b9e1777ce24e6ab08d28ac37d53af 557 Pfam PF07690 Major Facilitator Superfamily 58 453 8.5E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_37675 394b9e1777ce24e6ab08d28ac37d53af 557 Gene3D G3DSA:1.20.1720.10 55 277 3.4E-43 T 12-10-2018 AFR_37675 394b9e1777ce24e6ab08d28ac37d53af 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 168 1.2E-10 T 12-10-2018 AFR_37675 394b9e1777ce24e6ab08d28ac37d53af 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 57 81 1.2E-10 T 12-10-2018 AFR_37675 394b9e1777ce24e6ab08d28ac37d53af 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 178 202 1.2E-10 T 12-10-2018 AFR_37675 394b9e1777ce24e6ab08d28ac37d53af 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 444 463 1.2E-10 T 12-10-2018 AFR_20820 a91774a1fc9579e3f5d2e4725ea49417 291 SUPERFAMILY SSF47240 42 285 1.87E-63 T 12-10-2018 IPR009078 Ferritin-like superfamily AFR_20820 a91774a1fc9579e3f5d2e4725ea49417 291 PIRSF PIRSF037834 34 291 6.4E-87 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 AFR_20820 a91774a1fc9579e3f5d2e4725ea49417 291 Pfam PF05138 Phenylacetic acid catabolic protein 38 291 1.0E-81 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 AFR_20820 a91774a1fc9579e3f5d2e4725ea49417 291 Gene3D G3DSA:1.20.1260.10 36 291 1.0E-91 T 12-10-2018 IPR012347 Ferritin-like AFR_20820 a91774a1fc9579e3f5d2e4725ea49417 291 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 52 291 7.2E-74 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 Gene3D G3DSA:3.90.180.10 8 307 5.6E-90 T 12-10-2018 AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 103 8.0E-13 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 Pfam PF13602 Zinc-binding dehydrogenase 186 315 3.2E-22 T 12-10-2018 AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 SUPERFAMILY SSF50129 1 153 3.2E-37 T 12-10-2018 IPR011032 GroES-like superfamily AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 SMART SM00829 10 317 1.5E-37 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 SUPERFAMILY SSF51735 115 243 1.0E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_28880 90db5ae3ae7515e00930a9cf889e7ef6 331 Gene3D G3DSA:3.40.50.720 124 284 5.6E-90 T 12-10-2018 AFR_17160 718152191591fcb054dff86b3d7ea88b 262 SMART SM00382 30 234 6.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_17160 718152191591fcb054dff86b3d7ea88b 262 Gene3D G3DSA:3.40.50.300 1 244 1.3E-51 T 12-10-2018 AFR_17160 718152191591fcb054dff86b3d7ea88b 262 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_17160 718152191591fcb054dff86b3d7ea88b 262 SUPERFAMILY SSF52540 4 233 1.68E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_17160 718152191591fcb054dff86b3d7ea88b 262 Pfam PF00005 ABC transporter 22 178 1.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01485 613ff432e2667457b09f1407d87562a3 432 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 165 187 - T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_01485 613ff432e2667457b09f1407d87562a3 432 Gene3D G3DSA:3.40.630.10 107 432 1.6E-108 T 12-10-2018 AFR_01485 613ff432e2667457b09f1407d87562a3 432 Pfam PF00246 Zinc carboxypeptidase 124 409 4.4E-65 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_01485 613ff432e2667457b09f1407d87562a3 432 SMART SM00631 114 405 3.8E-92 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_01485 613ff432e2667457b09f1407d87562a3 432 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 309 319 - T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_01485 613ff432e2667457b09f1407d87562a3 432 SUPERFAMILY SSF53187 113 418 2.16E-83 T 12-10-2018 AFR_01485 613ff432e2667457b09f1407d87562a3 432 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 306 319 1.2E-11 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_01485 613ff432e2667457b09f1407d87562a3 432 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 165 179 1.2E-11 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_01485 613ff432e2667457b09f1407d87562a3 432 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 247 255 1.2E-11 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_01485 613ff432e2667457b09f1407d87562a3 432 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 140 152 1.2E-11 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Pfam PF00931 NB-ARC domain 263 456 4.2E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Gene3D G3DSA:1.10.10.10 1 95 6.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Gene3D G3DSA:1.25.40.10 98 252 4.2E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SMART SM01043 100 236 2.7E-29 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SMART SM00028 701 734 9.8E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SMART SM00028 781 814 8.9E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SMART SM00028 861 894 0.57 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SMART SM00028 821 854 0.36 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SMART SM00028 741 774 0.0041 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Pfam PF13424 Tetratricopeptide repeat 823 893 1.5E-13 T 12-10-2018 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Pfam PF13424 Tetratricopeptide repeat 741 812 1.2E-14 T 12-10-2018 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Gene3D G3DSA:3.40.50.300 253 360 4.3E-5 T 12-10-2018 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SUPERFAMILY SSF52540 248 513 1.04E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SMART SM00862 16 93 1.1E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 PRINTS PR00364 Disease resistance protein signature 356 370 9.2E-10 T 12-10-2018 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 PRINTS PR00364 Disease resistance protein signature 277 292 9.2E-10 T 12-10-2018 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 PRINTS PR00364 Disease resistance protein signature 444 458 9.2E-10 T 12-10-2018 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Gene3D G3DSA:1.25.40.10 597 811 8.3E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Gene3D G3DSA:1.25.40.10 812 914 3.5E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 92 6.0E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Pfam PF13181 Tetratricopeptide repeat 701 730 0.086 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SUPERFAMILY SSF46894 2 93 8.22E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 Pfam PF03704 Bacterial transcriptional activator domain 100 234 1.4E-25 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SUPERFAMILY SSF48452 701 891 1.03E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06770 339e2dba04976054ad4cf95d0b5f8eb9 915 SUPERFAMILY SSF48452 97 242 1.14E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 1.9E-56 T 12-10-2018 AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 7.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 SUPERFAMILY SSF51735 6 250 4.83E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 Gene3D G3DSA:3.40.50.720 5 248 1.9E-76 T 12-10-2018 AFR_31385 89683ae6d9c651ca76bcb4d83004fb5e 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_31940 f99184b5ecac12b8fe9abb3dec1574a8 377 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 320 1.6E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_31940 f99184b5ecac12b8fe9abb3dec1574a8 377 SMART SM00382 54 250 6.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_31940 f99184b5ecac12b8fe9abb3dec1574a8 377 Gene3D G3DSA:3.40.50.300 14 355 4.3E-86 T 12-10-2018 AFR_31940 f99184b5ecac12b8fe9abb3dec1574a8 377 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_31940 f99184b5ecac12b8fe9abb3dec1574a8 377 Pfam PF00005 ABC transporter 46 200 1.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31940 f99184b5ecac12b8fe9abb3dec1574a8 377 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 251 342 3.4E-21 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_31940 f99184b5ecac12b8fe9abb3dec1574a8 377 SUPERFAMILY SSF52540 30 271 6.39E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07865 c8b8000082cc84ab9e4371a2da510b7b 264 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07865 c8b8000082cc84ab9e4371a2da510b7b 264 SMART SM00382 27 216 7.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_07865 c8b8000082cc84ab9e4371a2da510b7b 264 Gene3D G3DSA:3.40.50.300 3 256 4.0E-65 T 12-10-2018 AFR_07865 c8b8000082cc84ab9e4371a2da510b7b 264 Pfam PF00005 ABC transporter 20 166 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_07865 c8b8000082cc84ab9e4371a2da510b7b 264 SUPERFAMILY SSF52540 3 228 1.43E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06215 09103e199e9c01d78309831288c46bdc 127 Pfam PF07883 Cupin domain 38 93 7.9E-14 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_06215 09103e199e9c01d78309831288c46bdc 127 Gene3D G3DSA:2.60.120.10 2 105 1.2E-34 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_06215 09103e199e9c01d78309831288c46bdc 127 SUPERFAMILY SSF51182 3 113 4.07E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_08785 45498715847eb4a56ef81dcfbe0fdc2f 155 Pfam PF12802 MarR family 21 74 5.3E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_08785 45498715847eb4a56ef81dcfbe0fdc2f 155 SUPERFAMILY SSF46785 5 106 1.56E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_08785 45498715847eb4a56ef81dcfbe0fdc2f 155 Gene3D G3DSA:1.10.10.10 2 87 1.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38790 1467824ae0e9e8fb237039e18b9d3eaa 172 Pfam PF05685 Putative restriction endonuclease 21 163 6.8E-15 T 12-10-2018 IPR008538 Domain of unknown function DUF820 AFR_38790 1467824ae0e9e8fb237039e18b9d3eaa 172 SUPERFAMILY SSF52980 15 157 1.07E-14 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_38790 1467824ae0e9e8fb237039e18b9d3eaa 172 Gene3D G3DSA:3.90.1570.10 12 152 2.3E-11 T 12-10-2018 AFR_14840 1f8616cd95905711bb052f3500f258c2 523 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 122 134 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_14840 1f8616cd95905711bb052f3500f258c2 523 Gene3D G3DSA:3.30.200.20 1 82 1.8E-17 T 12-10-2018 AFR_14840 1f8616cd95905711bb052f3500f258c2 523 Gene3D G3DSA:1.10.510.10 83 267 2.0E-44 T 12-10-2018 AFR_14840 1f8616cd95905711bb052f3500f258c2 523 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 10 32 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_14840 1f8616cd95905711bb052f3500f258c2 523 SUPERFAMILY SSF56112 2 256 2.56E-66 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_14840 1f8616cd95905711bb052f3500f258c2 523 SMART SM00220 4 255 3.3E-49 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_14840 1f8616cd95905711bb052f3500f258c2 523 Pfam PF00069 Protein kinase domain 4 253 6.2E-44 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_40560 3d17feb03a59bc393db26619880d4a1d 120 SUPERFAMILY SSF52172 1 118 5.41E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_40560 3d17feb03a59bc393db26619880d4a1d 120 SMART SM00448 1 115 1.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40560 3d17feb03a59bc393db26619880d4a1d 120 Pfam PF00072 Response regulator receiver domain 3 111 1.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40560 3d17feb03a59bc393db26619880d4a1d 120 Gene3D G3DSA:3.40.50.2300 1 119 7.0E-29 T 12-10-2018 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 Pfam PF00072 Response regulator receiver domain 4 115 7.8E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 3.6E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 SMART SM00448 2 115 1.2E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 Gene3D G3DSA:3.40.50.12740 3 214 3.4E-70 T 12-10-2018 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 SUPERFAMILY SSF46894 135 215 3.13E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 SMART SM00421 151 208 5.2E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28830 7e9614bcf76fe540ae5972817d10476e 218 SUPERFAMILY SSF52172 3 133 6.83E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_20755 1eac691ffac0fea829534010d2983a85 447 Gene3D G3DSA:3.30.1330.60 148 290 4.3E-29 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFR_20755 1eac691ffac0fea829534010d2983a85 447 PRINTS PR01021 OMPA domain signature 224 240 3.5E-9 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFR_20755 1eac691ffac0fea829534010d2983a85 447 PRINTS PR01021 OMPA domain signature 179 201 3.5E-9 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFR_20755 1eac691ffac0fea829534010d2983a85 447 PRINTS PR01021 OMPA domain signature 209 224 3.5E-9 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFR_20755 1eac691ffac0fea829534010d2983a85 447 Pfam PF00691 OmpA family 179 274 3.9E-13 T 12-10-2018 IPR006665 OmpA-like domain AFR_20755 1eac691ffac0fea829534010d2983a85 447 SUPERFAMILY SSF103088 168 280 3.27E-26 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFR_22815 c629786c2a13c6ac94e978d30e5c7491 250 SUPERFAMILY SSF52467 4 249 5.54E-82 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_22815 c629786c2a13c6ac94e978d30e5c7491 250 Gene3D G3DSA:3.40.50.1220 16 246 1.8E-83 T 12-10-2018 AFR_22815 c629786c2a13c6ac94e978d30e5c7491 250 Gene3D G3DSA:3.30.1600.10 33 174 1.8E-83 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily AFR_22815 c629786c2a13c6ac94e978d30e5c7491 250 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 17 250 57.982 T 12-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 AFR_22815 c629786c2a13c6ac94e978d30e5c7491 250 Pfam PF02146 Sir2 family 24 204 2.0E-49 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 AFR_19400 9f7bb854e3d9da2dc18e5b41af9e87e8 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 274 1.5E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_19400 9f7bb854e3d9da2dc18e5b41af9e87e8 281 Gene3D G3DSA:1.10.3720.10 8 268 2.7E-59 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19400 9f7bb854e3d9da2dc18e5b41af9e87e8 281 SUPERFAMILY SSF161098 5 281 6.73E-66 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36580 c03f2492314d875a7568260a2f2544ba 733 Pfam PF00270 DEAD/DEAH box helicase 297 450 3.8E-16 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_36580 c03f2492314d875a7568260a2f2544ba 733 SUPERFAMILY SSF50249 18 187 2.31E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_36580 c03f2492314d875a7568260a2f2544ba 733 Pfam PF17191 RecG wedge domain 18 184 4.8E-10 T 12-10-2018 IPR033454 RecG, wedge domain AFR_36580 c03f2492314d875a7568260a2f2544ba 733 SUPERFAMILY SSF52540 406 631 3.02E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36580 c03f2492314d875a7568260a2f2544ba 733 Gene3D G3DSA:2.40.50.140 49 147 2.6E-17 T 12-10-2018 AFR_36580 c03f2492314d875a7568260a2f2544ba 733 Gene3D G3DSA:3.40.50.300 218 465 1.3E-80 T 12-10-2018 AFR_36580 c03f2492314d875a7568260a2f2544ba 733 SMART SM00487 272 474 2.4E-26 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_36580 c03f2492314d875a7568260a2f2544ba 733 SUPERFAMILY SSF52540 193 467 5.29E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36580 c03f2492314d875a7568260a2f2544ba 733 SMART SM00490 536 621 2.0E-21 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_36580 c03f2492314d875a7568260a2f2544ba 733 Gene3D G3DSA:3.40.50.300 473 662 5.2E-53 T 12-10-2018 AFR_36580 c03f2492314d875a7568260a2f2544ba 733 Pfam PF00271 Helicase conserved C-terminal domain 543 620 2.3E-19 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 317 6.2E-106 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 SMART SM00840 346 407 6.0E-17 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 Gene3D G3DSA:1.20.120.640 311 467 8.6E-36 T 12-10-2018 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 468 34.853 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 Gene3D G3DSA:3.40.50.620 1 310 2.2E-112 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 196 214 1.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 227 248 1.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 SUPERFAMILY SSF52374 4 317 7.51E-78 T 12-10-2018 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 SUPERFAMILY SSF47323 322 467 2.22E-33 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 466 8.9E-127 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFR_41100 933248385144ca7d1a9bb7df31ae535a 471 Pfam PF09190 DALR domain 346 399 5.0E-12 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFR_39150 dc243b7fe7df3a366674f13264990649 471 Pfam PF06029 AlkA N-terminal domain 197 312 1.5E-31 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal AFR_39150 dc243b7fe7df3a366674f13264990649 471 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 318 457 3.6E-6 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_39150 dc243b7fe7df3a366674f13264990649 471 SUPERFAMILY SSF55945 197 293 8.95E-24 T 12-10-2018 AFR_39150 dc243b7fe7df3a366674f13264990649 471 SMART SM00342 100 183 3.8E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_39150 dc243b7fe7df3a366674f13264990649 471 Pfam PF12833 Helix-turn-helix domain 106 185 5.7E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_39150 dc243b7fe7df3a366674f13264990649 471 SUPERFAMILY SSF57884 3 83 1.7E-32 T 12-10-2018 IPR035451 Ada-like domain superfamily AFR_39150 dc243b7fe7df3a366674f13264990649 471 Gene3D G3DSA:3.40.10.10 1 73 1.0E-29 T 12-10-2018 IPR035451 Ada-like domain superfamily AFR_39150 dc243b7fe7df3a366674f13264990649 471 SMART SM01009 197 312 1.6E-45 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal AFR_39150 dc243b7fe7df3a366674f13264990649 471 Gene3D G3DSA:1.10.340.30 313 421 5.6E-29 T 12-10-2018 AFR_39150 dc243b7fe7df3a366674f13264990649 471 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_39150 dc243b7fe7df3a366674f13264990649 471 SMART SM00478 329 470 9.6E-6 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_39150 dc243b7fe7df3a366674f13264990649 471 SUPERFAMILY SSF46689 137 186 1.52E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_39150 dc243b7fe7df3a366674f13264990649 471 SUPERFAMILY SSF48150 303 470 1.22E-37 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_39150 dc243b7fe7df3a366674f13264990649 471 Gene3D G3DSA:1.10.1670.10 423 471 4.8E-13 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFR_39150 dc243b7fe7df3a366674f13264990649 471 Gene3D G3DSA:3.30.310.20 197 312 2.8E-24 T 12-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily AFR_39150 dc243b7fe7df3a366674f13264990649 471 Gene3D G3DSA:1.10.10.60 83 192 8.1E-17 T 12-10-2018 AFR_39150 dc243b7fe7df3a366674f13264990649 471 Pfam PF02805 Metal binding domain of Ada 8 71 2.7E-29 T 12-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 Pfam PF13802 Galactose mutarotase-like 154 213 2.7E-17 T 12-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 Gene3D G3DSA:2.60.40.1180 660 742 1.5E-12 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 SUPERFAMILY SSF51445 244 579 1.48E-87 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 Gene3D G3DSA:2.60.40.1760 1 240 6.8E-72 T 12-10-2018 AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 SUPERFAMILY SSF51011 581 659 9.35E-21 T 12-10-2018 AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 SUPERFAMILY SSF117125 662 726 1.96E-14 T 12-10-2018 AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 Gene3D G3DSA:3.20.20.80 241 611 5.6E-147 T 12-10-2018 AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 Gene3D G3DSA:2.60.40.1180 612 659 4.1E-19 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 SUPERFAMILY SSF74650 1 242 2.42E-57 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_22430 76c7ceeb978cd1048697ee657d7b5c96 745 Pfam PF01055 Glycosyl hydrolases family 31 236 664 4.9E-116 T 12-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 AFR_26755 f1baa24274a76813e55f4d280d2bd545 194 Gene3D G3DSA:1.10.10.10 93 189 8.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26755 f1baa24274a76813e55f4d280d2bd545 194 Pfam PF00486 Transcriptional regulatory protein, C terminal 111 182 3.4E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_26755 f1baa24274a76813e55f4d280d2bd545 194 SUPERFAMILY SSF46894 98 183 6.29E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_26755 f1baa24274a76813e55f4d280d2bd545 194 SMART SM00862 110 182 1.3E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 SMART SM00382 346 516 4.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 SMART SM00382 30 239 5.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 SUPERFAMILY SSF52540 307 505 4.09E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 Pfam PF00005 ABC transporter 338 471 8.0E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 Gene3D G3DSA:3.40.50.300 3 282 1.2E-73 T 12-10-2018 AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 Gene3D G3DSA:3.40.50.300 283 556 1.2E-62 T 12-10-2018 AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 SUPERFAMILY SSF52540 13 238 5.33E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 Pfam PF00005 ABC transporter 21 188 2.9E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 Pfam PF12848 ABC transporter 227 303 2.8E-13 T 12-10-2018 IPR032781 ABC-transporter extension domain AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 555 5.1E-269 T 12-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 AFR_07390 adefcb97f1e41c99379e0fd7d456d94d 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 SUPERFAMILY SSF46785 4 85 7.02E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 8.6E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 Gene3D G3DSA:1.10.10.10 1 86 1.6E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 Gene3D G3DSA:3.40.190.10 104 277 6.8E-14 T 12-10-2018 AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 SUPERFAMILY SSF53850 90 275 7.06E-17 T 12-10-2018 AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 Pfam PF03466 LysR substrate binding domain 89 276 1.0E-16 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_15145 e98bf9ebbfcd2a2d2d8c87f17869ff20 279 Gene3D G3DSA:3.40.190.10 163 255 6.8E-14 T 12-10-2018 AFR_37750 b37fe7b294d5570737b3094e66275db8 298 Gene3D G3DSA:3.40.50.720 1 135 8.1E-35 T 12-10-2018 AFR_37750 b37fe7b294d5570737b3094e66275db8 298 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 113 4.4E-22 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_37750 b37fe7b294d5570737b3094e66275db8 298 Gene3D G3DSA:3.30.360.10 136 296 1.8E-14 T 12-10-2018 AFR_37750 b37fe7b294d5570737b3094e66275db8 298 SUPERFAMILY SSF51735 2 131 9.07E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37750 b37fe7b294d5570737b3094e66275db8 298 SUPERFAMILY SSF55347 143 243 5.89E-10 T 12-10-2018 AFR_15695 13aa13b014ceeaa3b58cd642cdd78895 261 SMART SM00346 22 110 3.7E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_15695 13aa13b014ceeaa3b58cd642cdd78895 261 Pfam PF01614 Bacterial transcriptional regulator 181 250 1.1E-5 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_15695 13aa13b014ceeaa3b58cd642cdd78895 261 Pfam PF09339 IclR helix-turn-helix domain 25 73 6.2E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_15695 13aa13b014ceeaa3b58cd642cdd78895 261 Gene3D G3DSA:1.10.10.10 21 95 7.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15695 13aa13b014ceeaa3b58cd642cdd78895 261 SUPERFAMILY SSF55781 86 252 1.5E-18 T 12-10-2018 AFR_15695 13aa13b014ceeaa3b58cd642cdd78895 261 SUPERFAMILY SSF46785 23 94 1.52E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15695 13aa13b014ceeaa3b58cd642cdd78895 261 Gene3D G3DSA:3.30.450.40 96 255 3.2E-14 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 347 6.7E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Pfam PF00072 Response regulator receiver domain 662 775 5.1E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 507 6.2E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SMART SM00388 282 347 3.6E-22 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SMART SM00073 812 910 3.4E-6 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SUPERFAMILY SSF55785 140 260 1.74E-15 T 12-10-2018 IPR035965 PAS domain superfamily AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Gene3D G3DSA:1.10.287.130 259 345 3.0E-26 T 12-10-2018 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Gene3D G3DSA:3.40.50.2300 523 641 2.4E-5 T 12-10-2018 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Pfam PF01627 Hpt domain 822 899 1.6E-14 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Gene3D G3DSA:3.30.450.20 151 258 3.9E-17 T 12-10-2018 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SUPERFAMILY SSF55874 336 507 1.22E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SMART SM00387 394 508 2.0E-38 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Gene3D G3DSA:1.20.120.160 801 907 6.3E-22 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Gene3D G3DSA:3.40.50.2300 657 780 6.0E-41 T 12-10-2018 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 266 6.9E-11 T 12-10-2018 IPR000014 PAS domain AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SMART SM00091 152 217 2.0E-4 T 12-10-2018 IPR000014 PAS domain AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Gene3D G3DSA:3.30.565.10 346 510 1.8E-52 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SUPERFAMILY SSF47384 270 348 3.53E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SUPERFAMILY SSF52172 521 638 3.08E-7 T 12-10-2018 IPR011006 CheY-like superfamily AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SMART SM00448 660 775 2.5E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 Pfam PF08448 PAS fold 159 263 1.3E-16 T 12-10-2018 IPR013656 PAS fold-4 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 486 8.2E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 461 8.2E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 8.2E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 505 8.2E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SUPERFAMILY SSF47226 758 899 9.55E-21 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFR_21765 9d9bbdc32351da7841b5897c89e2d432 912 SUPERFAMILY SSF52172 659 781 2.85E-38 T 12-10-2018 IPR011006 CheY-like superfamily AFR_14200 3764193967cd6992a869c2ac429db957 125 Gene3D G3DSA:3.30.1330.40 1 125 3.2E-34 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_14200 3764193967cd6992a869c2ac429db957 125 SUPERFAMILY SSF55298 2 125 1.73E-32 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_14200 3764193967cd6992a869c2ac429db957 125 Pfam PF01042 Endoribonuclease L-PSP 11 123 3.3E-25 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 Gene3D G3DSA:3.30.540.10 7 154 1.2E-40 T 12-10-2018 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 93 106 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 Pfam PF00459 Inositol monophosphatase family 15 244 1.4E-52 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 93 109 5.6E-37 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 188 209 5.6E-37 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 142 165 5.6E-37 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 49 69 5.6E-37 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 71 87 5.6E-37 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 5.6E-37 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 SUPERFAMILY SSF56655 14 267 2.62E-67 T 12-10-2018 AFR_35320 9b2f90ae2cf8726e0067b01447eba092 275 Gene3D G3DSA:3.40.190.80 155 272 8.4E-31 T 12-10-2018 AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 Pfam PF08281 Sigma-70, region 4 104 155 6.8E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 156 2.4E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 SUPERFAMILY SSF88946 6 84 5.49E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 Gene3D G3DSA:1.10.10.10 89 162 2.8E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 Gene3D G3DSA:3.10.450.50 163 289 9.9E-9 T 12-10-2018 AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 Pfam PF04542 Sigma-70 region 2 6 70 1.8E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 SUPERFAMILY SSF54427 169 288 8.31E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 SUPERFAMILY SSF88659 100 156 7.1E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_40810 6e9b3bdced25111e41f91d7537e2570a 294 Gene3D G3DSA:1.10.1740.10 6 83 1.9E-8 T 12-10-2018 AFR_00930 72c8d895cb2f5653a91ebace0d727441 284 SUPERFAMILY SSF50022 180 282 1.44E-25 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_00930 72c8d895cb2f5653a91ebace0d727441 284 Pfam PF00355 Rieske [2Fe-2S] domain 181 268 4.9E-15 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFR_00930 72c8d895cb2f5653a91ebace0d727441 284 Gene3D G3DSA:2.102.10.10 177 284 7.3E-25 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_25165 d74f1b9db68455fa0771c653b7bb8bb9 198 SUPERFAMILY SSF53597 47 186 5.11E-21 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_25165 d74f1b9db68455fa0771c653b7bb8bb9 198 Pfam PF01872 RibD C-terminal domain 16 174 2.2E-15 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_25165 d74f1b9db68455fa0771c653b7bb8bb9 198 Gene3D G3DSA:3.40.430.10 10 196 6.4E-38 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_37960 cd1964cb138a27782bdd64cd07c4e0c5 305 Pfam PF00005 ABC transporter 23 162 6.5E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_37960 cd1964cb138a27782bdd64cd07c4e0c5 305 SUPERFAMILY SSF52540 5 223 1.47E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37960 cd1964cb138a27782bdd64cd07c4e0c5 305 SMART SM00382 32 218 2.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37960 cd1964cb138a27782bdd64cd07c4e0c5 305 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_37960 cd1964cb138a27782bdd64cd07c4e0c5 305 Gene3D G3DSA:3.40.50.300 3 227 5.9E-58 T 12-10-2018 AFR_19205 ba6b80152a62dd7d2c266bcb69c1423c 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 41 99 6.3E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_19205 ba6b80152a62dd7d2c266bcb69c1423c 480 Pfam PF00155 Aminotransferase class I and II 143 475 4.8E-17 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_19205 ba6b80152a62dd7d2c266bcb69c1423c 480 Gene3D G3DSA:1.10.10.10 37 120 5.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19205 ba6b80152a62dd7d2c266bcb69c1423c 480 SMART SM00345 40 99 3.4E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_19205 ba6b80152a62dd7d2c266bcb69c1423c 480 SUPERFAMILY SSF53383 130 479 8.38E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_19205 ba6b80152a62dd7d2c266bcb69c1423c 480 Gene3D G3DSA:3.40.640.10 125 474 1.3E-101 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_19205 ba6b80152a62dd7d2c266bcb69c1423c 480 SUPERFAMILY SSF46785 35 103 2.2E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_42915 89ad0df8d6962c1a3769bb81a5e792a5 514 SMART SM00220 34 260 1.2E-4 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_42915 89ad0df8d6962c1a3769bb81a5e792a5 514 SUPERFAMILY SSF56112 30 245 2.49E-23 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_42915 89ad0df8d6962c1a3769bb81a5e792a5 514 Gene3D G3DSA:1.10.510.10 113 264 2.2E-39 T 12-10-2018 AFR_42915 89ad0df8d6962c1a3769bb81a5e792a5 514 Pfam PF00069 Protein kinase domain 85 172 8.0E-10 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_42915 89ad0df8d6962c1a3769bb81a5e792a5 514 Gene3D G3DSA:3.30.200.20 22 110 1.1E-9 T 12-10-2018 AFR_42915 89ad0df8d6962c1a3769bb81a5e792a5 514 Gene3D G3DSA:2.60.120.260 365 514 2.8E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_42915 89ad0df8d6962c1a3769bb81a5e792a5 514 SUPERFAMILY SSF49785 375 513 2.19E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26020 845083cd8d92bfa0179fc17af80dbfab 396 Pfam PF07730 Histidine kinase 190 255 3.8E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_26020 845083cd8d92bfa0179fc17af80dbfab 396 SUPERFAMILY SSF55874 278 385 2.82E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26020 845083cd8d92bfa0179fc17af80dbfab 396 Gene3D G3DSA:3.30.565.10 267 386 6.1E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33370 5cf2e3334e600139d82eabe2e7af3d90 389 Gene3D G3DSA:3.40.50.2000 2 376 6.7E-135 T 12-10-2018 AFR_33370 5cf2e3334e600139d82eabe2e7af3d90 389 SUPERFAMILY SSF53756 1 377 2.31E-70 T 12-10-2018 AFR_33370 5cf2e3334e600139d82eabe2e7af3d90 389 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 206 348 1.6E-17 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 AFR_33370 5cf2e3334e600139d82eabe2e7af3d90 389 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 271 312 - T 12-10-2018 IPR035595 UDP-glycosyltransferase family, conserved site Reactome: R-HSA-156588 AFR_33370 5cf2e3334e600139d82eabe2e7af3d90 389 Gene3D G3DSA:3.40.50.2000 205 364 6.7E-135 T 12-10-2018 AFR_33370 5cf2e3334e600139d82eabe2e7af3d90 389 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 3 379 7.8E-118 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 AFR_33230 6fe88b1cc613efa7eb9d3fde6f02f361 97 SUPERFAMILY SSF57850 4 90 9.65E-29 T 12-10-2018 AFR_33230 6fe88b1cc613efa7eb9d3fde6f02f361 97 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 22 86 1.2E-11 T 12-10-2018 IPR001607 Zinc finger, UBP-type GO:0008270 AFR_33230 6fe88b1cc613efa7eb9d3fde6f02f361 97 Gene3D G3DSA:3.30.40.10 3 89 3.9E-30 T 12-10-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type AFR_34965 ddf629946a7534ada4925f1b51e1b751 285 Gene3D G3DSA:3.40.50.300 50 274 5.1E-51 T 12-10-2018 AFR_34965 ddf629946a7534ada4925f1b51e1b751 285 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 53 216 8.5E-37 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFR_34965 ddf629946a7534ada4925f1b51e1b751 285 Pfam PF13500 AAA domain 52 228 5.3E-29 T 12-10-2018 AFR_34965 ddf629946a7534ada4925f1b51e1b751 285 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 49 254 23.747 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFR_34965 ddf629946a7534ada4925f1b51e1b751 285 SUPERFAMILY SSF52540 52 222 3.01E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 Pfam PF00364 Biotin-requiring enzyme 5 78 1.6E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 Gene3D G3DSA:3.30.559.10 237 479 3.0E-78 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 250 478 3.6E-77 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 Gene3D G3DSA:2.40.50.100 1 83 1.4E-23 T 12-10-2018 AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 SUPERFAMILY SSF51230 3 85 9.03E-26 T 12-10-2018 IPR011053 Single hybrid motif AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 Gene3D G3DSA:4.10.320.10 179 230 6.1E-15 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 SUPERFAMILY SSF47005 184 227 4.84E-10 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 SUPERFAMILY SSF52777 240 479 1.47E-76 T 12-10-2018 AFR_00480 b3c89b214b31b76f6e62e24fa3a44126 482 Pfam PF02817 e3 binding domain 189 223 6.6E-13 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 AFR_41795 5b80943067beec04e689f6f35d9d13d4 335 Gene3D G3DSA:1.10.3720.10 114 331 6.0E-26 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41795 5b80943067beec04e689f6f35d9d13d4 335 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 35 71 1.9E-12 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFR_41795 5b80943067beec04e689f6f35d9d13d4 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 335 1.3E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_41795 5b80943067beec04e689f6f35d9d13d4 335 SUPERFAMILY SSF161098 119 317 1.96E-27 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 431 450 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 SUPERFAMILY SSF52467 188 367 2.89E-45 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 SUPERFAMILY SSF52518 3 173 1.37E-32 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 Gene3D G3DSA:3.40.50.970 1 177 6.5E-42 T 12-10-2018 AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 332 2.3E-32 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 Gene3D G3DSA:3.40.50.1220 188 363 1.4E-50 T 12-10-2018 AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 SUPERFAMILY SSF52518 367 557 7.42E-46 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 395 546 9.1E-32 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 164 7.5E-36 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFR_15705 ab9487545643a350f40e7b5fd0b12c63 559 Gene3D G3DSA:3.40.50.970 364 558 7.6E-50 T 12-10-2018 AFR_41545 85ac415d691712ef14c0a42d519ad648 191 Gene3D G3DSA:3.40.50.2020 4 191 4.8E-64 T 12-10-2018 AFR_41545 85ac415d691712ef14c0a42d519ad648 191 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 14 184 2.4E-62 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 AFR_41545 85ac415d691712ef14c0a42d519ad648 191 Pfam PF00156 Phosphoribosyl transferase domain 20 170 6.0E-21 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFR_41545 85ac415d691712ef14c0a42d519ad648 191 SUPERFAMILY SSF53271 8 188 5.11E-52 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 SUPERFAMILY SSF46785 9 74 2.4E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 Gene3D G3DSA:1.10.10.10 7 71 6.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 SUPERFAMILY SSF48008 76 205 1.02E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 Gene3D G3DSA:1.20.120.530 74 216 8.0E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 1.1E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 SMART SM00895 80 202 3.7E-16 T 12-10-2018 IPR011711 GntR, C-terminal AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 SMART SM00345 12 70 2.2E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 Pfam PF07729 FCD domain 80 201 1.1E-23 T 12-10-2018 IPR011711 GntR, C-terminal AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 2.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_15715 f702575b64b3f5493072c2624e7f15ff 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 2.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 126 20.461 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 126 3.2E-27 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 124 6.0E-36 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 Gene3D G3DSA:1.10.1200.120 1 128 6.3E-37 T 12-10-2018 IPR036019 Gated mechanosensitive channel AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 SUPERFAMILY SSF81330 10 121 3.92E-25 T 12-10-2018 IPR036019 Gated mechanosensitive channel AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 76 84 3.6E-7 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 86 95 3.6E-7 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFR_01200 aeafd2e1c6ee0334663d75269bc70ba1 147 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 3.6E-7 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 Pfam PF00672 HAMP domain 143 189 1.4E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 Gene3D G3DSA:3.30.565.10 277 424 4.5E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 Gene3D G3DSA:1.10.287.130 146 267 4.4E-20 T 12-10-2018 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 SUPERFAMILY SSF47384 179 263 6.08E-8 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 3.5E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 3.5E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 SUPERFAMILY SSF55874 272 414 2.62E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 195 260 9.3E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 SMART SM00387 315 418 1.5E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 SMART SM00304 141 193 7.1E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_31180 cbf0791b6cb1a6380827816bd8fb6a8b 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 412 1.6E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_35905 6e18465f015cc179a55da279f3c7b44e 490 Pfam PF05193 Peptidase M16 inactive domain 235 412 1.4E-38 T 12-10-2018 IPR007863 Peptidase M16, C-terminal AFR_35905 6e18465f015cc179a55da279f3c7b44e 490 Gene3D G3DSA:3.30.830.10 298 485 5.7E-59 T 12-10-2018 AFR_35905 6e18465f015cc179a55da279f3c7b44e 490 Gene3D G3DSA:3.30.830.10 69 282 3.7E-64 T 12-10-2018 AFR_35905 6e18465f015cc179a55da279f3c7b44e 490 SUPERFAMILY SSF63411 69 277 2.38E-52 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_35905 6e18465f015cc179a55da279f3c7b44e 490 Pfam PF00675 Insulinase (Peptidase family M16) 79 223 9.3E-39 T 12-10-2018 IPR011765 Peptidase M16, N-terminal AFR_35905 6e18465f015cc179a55da279f3c7b44e 490 SUPERFAMILY SSF63411 297 484 1.08E-48 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_35905 6e18465f015cc179a55da279f3c7b44e 490 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 100 123 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 Gene3D G3DSA:3.30.70.2520 306 397 9.4E-24 T 12-10-2018 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 Pfam PF01565 FAD binding domain 28 157 1.2E-23 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 PIRSF PIRSF000136 6 437 1.7E-108 T 12-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 Pfam PF04030 D-arabinono-1,4-lactone oxidase 180 434 1.4E-71 T 12-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 Gene3D G3DSA:3.30.43.10 9 77 9.6E-18 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 14 436 9.2E-113 T 12-10-2018 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 Gene3D G3DSA:1.10.45.10 399 436 1.8E-8 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 SUPERFAMILY SSF56176 8 185 2.94E-40 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_01910 88712cb6d30b5bd8b841e11875b1e24d 437 Gene3D G3DSA:3.30.465.10 80 196 7.7E-36 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 SMART SM01065 500 589 4.1E-25 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 PRINTS PR00110 Alpha-amylase signature 217 228 4.8E-25 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 PRINTS PR00110 Alpha-amylase signature 302 314 4.8E-25 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 PRINTS PR00110 Alpha-amylase signature 245 263 4.8E-25 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 PRINTS PR00110 Alpha-amylase signature 121 132 4.8E-25 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 PRINTS PR00110 Alpha-amylase signature 89 106 4.8E-25 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 Pfam PF00128 Alpha amylase, catalytic domain 89 318 4.7E-15 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 Pfam PF00686 Starch binding domain 499 583 5.8E-27 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 SUPERFAMILY SSF49452 499 593 2.94E-29 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 SUPERFAMILY SSF51445 41 394 2.16E-86 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_19380 ced2e7bcb904966e879808013b6606ab 594 Gene3D G3DSA:3.20.20.80 34 397 2.1E-149 T 12-10-2018 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 SUPERFAMILY SSF51011 397 486 7.2E-32 T 12-10-2018 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 SMART SM00642 42 392 4.4E-79 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 SMART SM00632 401 486 1.1E-41 T 12-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 404 483 1.6E-13 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFR_19380 ced2e7bcb904966e879808013b6606ab 594 Gene3D G3DSA:2.60.40.10 489 594 1.8E-31 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_19380 ced2e7bcb904966e879808013b6606ab 594 Gene3D G3DSA:2.60.40.1180 398 486 1.8E-33 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 Pfam PF00072 Response regulator receiver domain 2 97 1.3E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 Pfam PF00486 Transcriptional regulatory protein, C terminal 129 205 1.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 SUPERFAMILY SSF52172 2 111 2.13E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 SUPERFAMILY SSF46894 103 206 2.01E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 Gene3D G3DSA:1.10.10.10 108 208 2.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 SMART SM00862 129 205 8.5E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 SMART SM00448 1 97 2.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13320 1341753bc4c2c4190fc33d9dcc074a68 210 Gene3D G3DSA:3.40.50.2300 1 107 7.8E-31 T 12-10-2018 AFR_31800 ba3e015d06d5baa5a07d43e865afe537 333 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 330 9.0E-80 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related AFR_31800 ba3e015d06d5baa5a07d43e865afe537 333 Pfam PF00296 Luciferase-like monooxygenase 4 303 1.9E-64 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_31800 ba3e015d06d5baa5a07d43e865afe537 333 Gene3D G3DSA:3.20.20.30 1 331 3.2E-99 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_31800 ba3e015d06d5baa5a07d43e865afe537 333 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 2 329 6.1E-143 T 12-10-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase AFR_31800 ba3e015d06d5baa5a07d43e865afe537 333 SUPERFAMILY SSF51679 1 329 7.46E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 488 650 3.5E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 Gene3D G3DSA:3.30.450.20 352 484 1.1E-18 T 12-10-2018 AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 Pfam PF08448 PAS fold 372 481 1.9E-9 T 12-10-2018 IPR013656 PAS fold-4 AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 SUPERFAMILY SSF55073 495 657 2.88E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 Gene3D G3DSA:3.30.70.270 485 667 1.1E-57 T 12-10-2018 AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 Pfam PF00990 Diguanylate cyclase, GGDEF domain 490 649 1.3E-45 T 12-10-2018 IPR000160 GGDEF domain AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 SMART SM00052 665 912 8.3E-125 T 12-10-2018 IPR001633 EAL domain AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 SMART SM00091 365 431 1.9E-5 T 12-10-2018 IPR000014 PAS domain AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 362 486 8.0E-17 T 12-10-2018 IPR000014 PAS domain AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 Gene3D G3DSA:3.20.20.450 668 920 2.1E-104 T 12-10-2018 IPR035919 EAL domain superfamily AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 Pfam PF00563 EAL domain 671 907 3.3E-73 T 12-10-2018 IPR001633 EAL domain AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 SUPERFAMILY SSF55785 357 477 1.44E-17 T 12-10-2018 IPR035965 PAS domain superfamily AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 SMART SM00267 479 655 3.6E-62 T 12-10-2018 IPR000160 GGDEF domain AFR_33700 a2044831f2be2a8e543b8e424dbdcf51 927 SUPERFAMILY SSF141868 671 919 3.27E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 Gene3D G3DSA:3.40.50.920 499 628 3.3E-27 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 SMART SM00861 320 484 5.4E-57 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 Pfam PF02780 Transketolase, C-terminal domain 503 616 3.1E-25 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 SUPERFAMILY SSF52922 503 623 3.8E-23 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 ProSitePatterns PS00802 Transketolase signature 2. 426 442 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 8 625 40.763 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 10 284 3.6E-105 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 Gene3D G3DSA:3.40.50.970 318 490 2.5E-58 T 12-10-2018 AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 Pfam PF02779 Transketolase, pyrimidine binding domain 320 483 1.4E-35 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 623 1.9E-186 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 SUPERFAMILY SSF52518 7 350 2.5E-73 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_14335 78e2949470f916edeca7ab44ef7d1027 641 SUPERFAMILY SSF52518 300 483 6.68E-55 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 SUPERFAMILY SSF53822 62 333 6.1E-79 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 Gene3D G3DSA:3.40.50.2300 65 312 4.3E-74 T 12-10-2018 AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 Gene3D G3DSA:3.40.50.2300 162 291 4.3E-74 T 12-10-2018 AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 48 9.4E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 Pfam PF13377 Periplasmic binding protein-like domain 170 331 2.5E-41 T 12-10-2018 AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 SUPERFAMILY SSF47413 3 52 1.74E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 SMART SM00354 3 72 1.4E-10 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_25090 f786f6b2cb64702a1c0342e33a5f366d 336 Gene3D G3DSA:1.10.260.40 2 60 6.5E-13 T 12-10-2018 AFR_27975 df553c6fd0096ade2cead2aaecd2ef80 189 SMART SM00926 44 98 4.3E-20 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27975 df553c6fd0096ade2cead2aaecd2ef80 189 SUPERFAMILY SSF53706 43 189 2.49E-45 T 12-10-2018 AFR_27975 df553c6fd0096ade2cead2aaecd2ef80 189 Gene3D G3DSA:3.40.50.740 101 189 4.5E-30 T 12-10-2018 AFR_27975 df553c6fd0096ade2cead2aaecd2ef80 189 Gene3D G3DSA:2.20.25.90 40 99 1.6E-19 T 12-10-2018 AFR_27975 df553c6fd0096ade2cead2aaecd2ef80 189 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 46 92 2.3E-18 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33865 7dfb40d20435fefba0268f84b240e42a 331 SUPERFAMILY SSF53822 39 324 7.26E-59 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_33865 7dfb40d20435fefba0268f84b240e42a 331 Pfam PF13407 Periplasmic binding protein domain 41 296 2.4E-47 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_33865 7dfb40d20435fefba0268f84b240e42a 331 Gene3D G3DSA:3.40.50.2300 143 313 1.5E-62 T 12-10-2018 AFR_33865 7dfb40d20435fefba0268f84b240e42a 331 Gene3D G3DSA:3.40.50.2300 50 305 1.5E-62 T 12-10-2018 AFR_34895 0df075ec6f88a6f1a0a52b12472d94b8 115 Pfam PF12680 SnoaL-like domain 7 106 2.9E-12 T 12-10-2018 IPR037401 SnoaL-like domain AFR_34895 0df075ec6f88a6f1a0a52b12472d94b8 115 SUPERFAMILY SSF54427 3 111 1.11E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_34895 0df075ec6f88a6f1a0a52b12472d94b8 115 Gene3D G3DSA:3.10.450.50 3 112 1.7E-21 T 12-10-2018 AFR_03480 7e3ca2cfa28169fc43fa70cbd8063315 146 Pfam PF12802 MarR family 30 87 4.2E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_03480 7e3ca2cfa28169fc43fa70cbd8063315 146 SMART SM00347 24 123 7.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_03480 7e3ca2cfa28169fc43fa70cbd8063315 146 Gene3D G3DSA:1.10.10.10 2 134 1.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03480 7e3ca2cfa28169fc43fa70cbd8063315 146 SUPERFAMILY SSF46785 10 129 6.37E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 Pfam PF17203 Single cache domain 3 35 167 2.3E-24 T 12-10-2018 IPR033463 Single cache domain 3 AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 SUPERFAMILY SSF103190 39 165 3.18E-34 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 Gene3D G3DSA:3.30.450.20 198 311 7.8E-21 T 12-10-2018 AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 Pfam PF00989 PAS fold 212 252 1.1E-5 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 SUPERFAMILY SSF55874 392 520 3.01E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 417 521 4.6E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 Gene3D G3DSA:3.30.450.20 34 169 4.3E-41 T 12-10-2018 AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 4.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 520 4.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 501 4.0E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 SUPERFAMILY SSF55785 211 274 6.11E-8 T 12-10-2018 IPR035965 PAS domain superfamily AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 SMART SM00091 211 277 1.1E-5 T 12-10-2018 IPR000014 PAS domain AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 SMART SM00387 414 523 4.4E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19955 91d99da92b6737b34a0c9ff4c66f1f2c 523 Gene3D G3DSA:3.30.565.10 381 523 9.8E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40975 ff5eb1a4dc5b86133a8a693cb90b2f90 273 SMART SM00495 226 273 1.8E-4 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_40975 ff5eb1a4dc5b86133a8a693cb90b2f90 273 Gene3D G3DSA:2.70.50.50 29 170 4.1E-47 T 12-10-2018 AFR_40975 ff5eb1a4dc5b86133a8a693cb90b2f90 273 Gene3D G3DSA:2.10.10.20 228 271 2.0E-16 T 12-10-2018 AFR_40975 ff5eb1a4dc5b86133a8a693cb90b2f90 273 SUPERFAMILY SSF81296 29 170 4.48E-35 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_40975 ff5eb1a4dc5b86133a8a693cb90b2f90 273 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 29 167 8.2E-15 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal AFR_40975 ff5eb1a4dc5b86133a8a693cb90b2f90 273 SUPERFAMILY SSF51055 228 270 4.05E-11 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_05710 e4dc0099bbc1085c50ca72a68f67c6d1 209 Hamap MF_00801 Endonuclease V [nfi]. 1 206 29.852 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 AFR_05710 e4dc0099bbc1085c50ca72a68f67c6d1 209 Gene3D G3DSA:3.30.2170.10 1 207 2.8E-77 T 12-10-2018 AFR_05710 e4dc0099bbc1085c50ca72a68f67c6d1 209 Pfam PF04493 Endonuclease V 15 197 1.1E-66 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 SUPERFAMILY SSF54826 3 136 2.02E-33 T 12-10-2018 AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 133 2.6E-6 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 Gene3D G3DSA:3.20.20.120 129 433 1.1E-97 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 Pfam PF13378 Enolase C-terminal domain-like 202 419 1.2E-52 T 12-10-2018 IPR029065 Enolase C-terminal domain-like AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 SUPERFAMILY SSF51604 122 426 1.57E-60 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 SMART SM00922 196 292 4.1E-24 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 Gene3D G3DSA:3.30.390.10 1 128 4.6E-46 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFR_25260 810a9f28bce44cbc5b5c972cc1c6ed43 433 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 242 273 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 AFR_14450 23a30860ac5cc5c9417ccb09c899eba7 672 Gene3D G3DSA:3.20.20.140 293 421 1.6E-5 T 12-10-2018 AFR_14450 23a30860ac5cc5c9417ccb09c899eba7 672 SUPERFAMILY SSF51556 248 588 3.2E-20 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 SUPERFAMILY SSF52922 498 627 1.96E-23 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 SUPERFAMILY SSF52518 12 355 8.42E-70 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 Gene3D G3DSA:3.40.50.970 322 493 4.4E-58 T 12-10-2018 AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 SUPERFAMILY SSF52518 305 486 5.65E-53 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 Pfam PF02779 Transketolase, pyrimidine binding domain 324 485 4.6E-36 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 14 288 1.4E-108 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 Gene3D G3DSA:3.40.50.920 497 632 6.0E-26 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 SMART SM00861 324 488 1.2E-53 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 Pfam PF02780 Transketolase, C-terminal domain 503 619 2.5E-21 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 12 628 40.754 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 ProSitePatterns PS00802 Transketolase signature 2. 430 446 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_35250 41c48bc532a100c230aa364c9900a5e6 641 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 16 627 4.9E-185 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 SUPERFAMILY SSF51230 134 225 1.7E-27 T 12-10-2018 IPR011053 Single hybrid motif AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Gene3D G3DSA:3.30.559.10 354 609 1.1E-82 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 SUPERFAMILY SSF51230 2 95 1.57E-26 T 12-10-2018 IPR011053 Single hybrid motif AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 157 186 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 SUPERFAMILY SSF52777 362 602 8.01E-79 T 12-10-2018 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Pfam PF02817 e3 binding domain 305 337 5.3E-14 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 376 603 1.1E-74 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Gene3D G3DSA:4.10.320.10 298 344 1.9E-14 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 SUPERFAMILY SSF47005 300 342 4.19E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Gene3D G3DSA:2.40.50.100 128 233 2.1E-27 T 12-10-2018 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Gene3D G3DSA:2.40.50.100 3 101 9.0E-27 T 12-10-2018 AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Pfam PF00364 Biotin-requiring enzyme 5 76 1.2E-20 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 Pfam PF00364 Biotin-requiring enzyme 134 206 1.2E-22 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_09255 e1334f5c930ebc7c4154294f7f96112e 614 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 252 612 6.2E-150 T 12-10-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 AFR_10055 0d6d621ae7b4d42a927bd0400f7da990 112 SMART SM01152 19 99 1.7E-27 T 12-10-2018 IPR003746 Protein of unknown function DUF167 AFR_10055 0d6d621ae7b4d42a927bd0400f7da990 112 Gene3D G3DSA:3.30.1200.10 14 110 4.7E-20 T 12-10-2018 IPR036591 YggU-like superfamily AFR_10055 0d6d621ae7b4d42a927bd0400f7da990 112 Hamap MF_00634 UPF0235 protein YggU [yggU]. 19 110 15.097 T 12-10-2018 IPR003746 Protein of unknown function DUF167 AFR_10055 0d6d621ae7b4d42a927bd0400f7da990 112 SUPERFAMILY SSF69786 18 100 1.57E-19 T 12-10-2018 IPR036591 YggU-like superfamily AFR_10055 0d6d621ae7b4d42a927bd0400f7da990 112 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 23 97 2.1E-20 T 12-10-2018 IPR003746 Protein of unknown function DUF167 AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 Gene3D G3DSA:3.40.50.300 1 240 1.3E-72 T 12-10-2018 AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 SUPERFAMILY SSF55021 247 325 2.29E-15 T 12-10-2018 AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 Pfam PF00005 ABC transporter 22 169 3.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 Pfam PF09383 NIL domain 253 324 2.8E-18 T 12-10-2018 IPR018449 NIL domain AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 SMART SM00930 251 326 8.4E-18 T 12-10-2018 IPR018449 NIL domain AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 SMART SM00382 30 286 3.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 SUPERFAMILY SSF52540 1 238 2.92E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20425 79334659b77bde424c4dfca1b5625e7b 328 Gene3D G3DSA:3.30.70.260 243 328 8.6E-14 T 12-10-2018 AFR_29120 241161cf7d6385c8116d01c940bad9dc 408 Gene3D G3DSA:3.40.190.10 22 332 2.1E-45 T 12-10-2018 AFR_29120 241161cf7d6385c8116d01c940bad9dc 408 Pfam PF01547 Bacterial extracellular solute-binding protein 18 312 2.1E-21 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_29120 241161cf7d6385c8116d01c940bad9dc 408 SUPERFAMILY SSF53850 9 398 1.2E-41 T 12-10-2018 AFR_29120 241161cf7d6385c8116d01c940bad9dc 408 Gene3D G3DSA:3.40.190.10 126 369 2.1E-45 T 12-10-2018 AFR_30965 049657b7c703e193bd1e44354a44c455 161 Gene3D G3DSA:1.10.10.10 12 161 7.2E-47 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30965 049657b7c703e193bd1e44354a44c455 161 Pfam PF01638 HxlR-like helix-turn-helix 26 114 5.0E-23 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_30965 049657b7c703e193bd1e44354a44c455 161 SUPERFAMILY SSF46785 12 153 5.18E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17075 8e97bf8d95d554172bc401a0b1fc5b0c 203 SUPERFAMILY SSF53597 1 191 2.62E-28 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_17075 8e97bf8d95d554172bc401a0b1fc5b0c 203 Gene3D G3DSA:3.40.430.10 2 190 3.1E-40 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_17075 8e97bf8d95d554172bc401a0b1fc5b0c 203 Pfam PF01872 RibD C-terminal domain 2 185 1.0E-22 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_08165 4ba7bd39e3a59730a658b5d392b10c69 406 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 21 402 1.1E-80 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 AFR_08165 4ba7bd39e3a59730a658b5d392b10c69 406 SUPERFAMILY SSF109604 14 394 4.53E-60 T 12-10-2018 AFR_08165 4ba7bd39e3a59730a658b5d392b10c69 406 Pfam PF13286 Phosphohydrolase-associated domain 309 399 3.3E-22 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain AFR_08165 4ba7bd39e3a59730a658b5d392b10c69 406 Pfam PF01966 HD domain 58 199 2.9E-19 T 12-10-2018 IPR006674 HD domain AFR_08165 4ba7bd39e3a59730a658b5d392b10c69 406 SMART SM00471 54 209 4.3E-11 T 12-10-2018 IPR003607 HD/PDEase domain AFR_08165 4ba7bd39e3a59730a658b5d392b10c69 406 Gene3D G3DSA:1.10.3210.10 3 403 2.7E-90 T 12-10-2018 AFR_08780 9083df39d067cba945066014d5d5dfb1 304 Gene3D G3DSA:3.40.50.300 1 231 5.9E-51 T 12-10-2018 AFR_08780 9083df39d067cba945066014d5d5dfb1 304 SMART SM00382 31 209 2.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08780 9083df39d067cba945066014d5d5dfb1 304 SUPERFAMILY SSF52540 3 231 1.44E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08780 9083df39d067cba945066014d5d5dfb1 304 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_08780 9083df39d067cba945066014d5d5dfb1 304 Pfam PF00005 ABC transporter 23 161 4.3E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 3 310 1.2E-102 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 Pfam PF04542 Sigma-70 region 2 10 75 1.1E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 29 61 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 SUPERFAMILY SSF54427 193 293 2.57E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 SUPERFAMILY SSF88946 3 83 7.26E-24 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 Pfam PF08281 Sigma-70, region 4 126 178 1.3E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 Gene3D G3DSA:1.10.10.10 109 182 2.4E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 Gene3D G3DSA:1.10.1740.10 1 77 8.4E-23 T 12-10-2018 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 180 3.4E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 Pfam PF12680 SnoaL-like domain 201 293 4.8E-8 T 12-10-2018 IPR037401 SnoaL-like domain AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 Gene3D G3DSA:3.10.450.50 189 310 2.3E-14 T 12-10-2018 AFR_28475 a75f0287300d83306eb6d119e72d19dc 321 SUPERFAMILY SSF88659 123 180 5.98E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 Gene3D G3DSA:3.40.50.1820 2 271 9.1E-86 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 Pfam PF00561 alpha/beta hydrolase fold 21 255 4.8E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 3.0E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 3.0E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 3.0E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 PRINTS PR00412 Epoxide hydrolase signature 46 61 1.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 PRINTS PR00412 Epoxide hydrolase signature 26 44 1.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 PRINTS PR00412 Epoxide hydrolase signature 213 229 1.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 PRINTS PR00412 Epoxide hydrolase signature 247 269 1.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21480 0c2a487c12e2a9c6f27b8c262392eeed 272 SUPERFAMILY SSF53474 3 271 1.12E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Gene3D G3DSA:2.40.30.10 206 305 2.0E-32 T 12-10-2018 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 196 2.4E-19 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 PRINTS PR00315 GTP-binding elongation factor signature 146 155 6.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 PRINTS PR00315 GTP-binding elongation factor signature 94 104 6.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 PRINTS PR00315 GTP-binding elongation factor signature 65 73 6.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 PRINTS PR00315 GTP-binding elongation factor signature 22 35 6.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 PRINTS PR00315 GTP-binding elongation factor signature 110 121 6.1E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Gene3D G3DSA:3.30.70.2570 499 573 9.3E-34 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Gene3D G3DSA:3.30.70.870 306 387 1.5E-34 T 12-10-2018 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 SUPERFAMILY SSF50447 185 303 5.81E-23 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 SUPERFAMILY SSF52540 15 222 5.18E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Pfam PF06421 GTP-binding protein LepA C-terminus 508 612 4.8E-49 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Pfam PF00009 Elongation factor Tu GTP binding domain 19 201 6.6E-52 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Gene3D G3DSA:3.30.70.3380 388 497 2.5E-38 T 12-10-2018 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Gene3D G3DSA:3.40.50.300 15 205 2.1E-68 T 12-10-2018 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 SMART SM00838 417 505 1.6E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 SUPERFAMILY SSF54980 418 513 5.76E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Hamap MF_00071 Elongation factor 4 [lepA]. 1 617 280.645 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 TIGRFAM TIGR01393 lepA: elongation factor 4 19 614 4.5E-290 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 Pfam PF00679 Elongation factor G C-terminus 418 504 3.8E-23 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_07805 d337b6b94d39afdb754ca7defc06de3c 624 SUPERFAMILY SSF54980 311 390 5.76E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 SUPERFAMILY SSF55826 217 385 5.49E-10 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 Gene3D G3DSA:3.90.960.10 238 393 2.3E-199 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 92 464 4.1E-39 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 SUPERFAMILY SSF52954 466 570 1.8E-22 T 12-10-2018 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 132 140 3.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 102 113 3.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 142 153 3.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 66 84 3.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 573 34.347 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 SUPERFAMILY SSF55681 8 483 1.67E-87 T 12-10-2018 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 Gene3D G3DSA:3.40.50.800 1 556 2.3E-199 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 Gene3D G3DSA:3.30.930.10 9 470 2.3E-199 T 12-10-2018 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 Pfam PF03129 Anticodon binding domain 481 568 3.4E-13 T 12-10-2018 IPR004154 Anticodon-binding AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 Pfam PF04073 Aminoacyl-tRNA editing domain 254 383 6.2E-18 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFR_00110 3ba9d070ef112a1769bfa3ce2f45191a 573 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 2 568 2.8E-156 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 246 427 2.0E-25 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 PIRSF PIRSF000538 1 465 3.0E-81 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 TIGRFAM TIGR01312 XylB: xylulokinase 6 433 4.7E-119 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 SUPERFAMILY SSF53067 242 429 1.64E-42 T 12-10-2018 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 Gene3D G3DSA:3.30.420.40 239 470 2.5E-70 T 12-10-2018 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 SUPERFAMILY SSF53067 4 240 1.35E-50 T 12-10-2018 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 340 361 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 Gene3D G3DSA:3.30.420.40 1 238 2.4E-89 T 12-10-2018 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 127 139 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_07025 10937a2582a681fb97b70d6898bb4b91 471 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 222 9.3E-41 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFR_18440 b029dfc69949a8b0f6549b7cef69df03 312 Gene3D G3DSA:3.40.190.10 242 312 1.5E-9 T 12-10-2018 AFR_18440 b029dfc69949a8b0f6549b7cef69df03 312 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 302 1.7E-41 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 AFR_18440 b029dfc69949a8b0f6549b7cef69df03 312 Gene3D G3DSA:3.10.105.10 19 116 1.6E-10 T 12-10-2018 AFR_18440 b029dfc69949a8b0f6549b7cef69df03 312 Gene3D G3DSA:3.40.190.100 118 241 7.3E-22 T 12-10-2018 AFR_18440 b029dfc69949a8b0f6549b7cef69df03 312 SUPERFAMILY SSF53850 29 312 1.36E-50 T 12-10-2018 AFR_18200 f5601e5dd9ae345f5dcd7ef2a577e1ff 386 Pfam PF05787 Bacterial protein of unknown function (DUF839) 165 204 3.9E-11 T 12-10-2018 IPR008557 Protein of unknown function DUF839 AFR_18200 f5601e5dd9ae345f5dcd7ef2a577e1ff 386 Pfam PF05787 Bacterial protein of unknown function (DUF839) 123 151 5.3E-9 T 12-10-2018 IPR008557 Protein of unknown function DUF839 AFR_18200 f5601e5dd9ae345f5dcd7ef2a577e1ff 386 Gene3D G3DSA:2.130.10.10 257 377 4.4E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_18200 f5601e5dd9ae345f5dcd7ef2a577e1ff 386 SUPERFAMILY SSF63825 169 367 1.39E-15 T 12-10-2018 AFR_16210 25a7c62ab03410b5d945b66eee3df42d 426 Pfam PF07676 WD40-like Beta Propeller Repeat 98 124 0.13 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_16210 25a7c62ab03410b5d945b66eee3df42d 426 SUPERFAMILY SSF69304 49 375 3.53E-16 T 12-10-2018 AFR_16210 25a7c62ab03410b5d945b66eee3df42d 426 Gene3D G3DSA:2.120.10.30 183 405 2.7E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:3.40.50.12780 5 407 5.0E-135 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF47336 1651 1717 4.06E-8 T 12-10-2018 IPR036736 ACP-like superfamily AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SMART SM00823 Phosphopantetheine attachment site 1652 1721 0.07 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SMART SM00823 Phosphopantetheine attachment site 1571 1640 0.011 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SMART SM00823 Phosphopantetheine attachment site 520 589 1.2E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF52777 607 779 5.45E-46 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF00668 Condensation domain 604 1043 2.3E-79 T 12-10-2018 IPR001242 Condensation domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1595 1610 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF56801 1031 1584 3.27E-150 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 ProSitePatterns PS00012 Phosphopantetheine attachment site. 544 559 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF53474 1720 1978 1.59E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF13193 AMP-binding enzyme C-terminal domain 1474 1545 3.3E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 494 3.2E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF47336 1563 1636 1.44E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:3.40.50.1820 1644 1979 2.1E-74 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:3.40.50.12780 1061 1458 7.4E-140 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF47336 513 585 4.97E-20 T 12-10-2018 IPR036736 ACP-like superfamily AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF56801 7 533 1.96E-146 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:3.30.300.30 408 508 7.4E-32 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:3.30.300.30 1460 1559 2.8E-28 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:1.10.1200.10 1560 1639 5.5E-27 T 12-10-2018 IPR036736 ACP-like superfamily AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:1.10.1200.10 509 588 3.7E-27 T 12-10-2018 IPR036736 ACP-like superfamily AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:3.30.559.30 783 1033 4.0E-142 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 SUPERFAMILY SSF52777 786 1031 5.67E-57 T 12-10-2018 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF00501 AMP-binding enzyme 1069 1466 8.7E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF00501 AMP-binding enzyme 17 413 3.1E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1090 1490 4.6E-133 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 37 437 3.0E-130 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Gene3D G3DSA:3.30.559.10 606 968 4.0E-142 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF00550 Phosphopantetheine attachment site 522 585 1.7E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF00550 Phosphopantetheine attachment site 1654 1717 9.6E-5 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF00550 Phosphopantetheine attachment site 1573 1636 1.4E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_29235 7fab41bf683e57b35c6b883c33944e80 1988 Pfam PF00975 Thioesterase domain 1741 1860 3.0E-24 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 AFR_30500 2e5fd0143bd2699ba5a9634bb80af781 368 SUPERFAMILY SSF50952 56 351 1.7E-47 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_30500 2e5fd0143bd2699ba5a9634bb80af781 368 Gene3D G3DSA:2.120.10.30 35 367 1.8E-117 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_30500 2e5fd0143bd2699ba5a9634bb80af781 368 Pfam PF07995 Glucose / Sorbosone dehydrogenase 63 350 7.1E-73 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_22635 20512dbb19fc2f152d1a85e4d00bfb88 352 Gene3D G3DSA:1.10.600.10 2 352 8.0E-106 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_22635 20512dbb19fc2f152d1a85e4d00bfb88 352 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 230 242 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFR_22635 20512dbb19fc2f152d1a85e4d00bfb88 352 SUPERFAMILY SSF48576 17 351 8.64E-76 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_22635 20512dbb19fc2f152d1a85e4d00bfb88 352 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 87 101 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFR_22635 20512dbb19fc2f152d1a85e4d00bfb88 352 Pfam PF00348 Polyprenyl synthetase 41 288 7.7E-50 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFR_01845 3545614f8a2f231ff24f439d8d6b7307 410 Gene3D G3DSA:3.40.50.300 173 384 6.0E-56 T 12-10-2018 AFR_01845 3545614f8a2f231ff24f439d8d6b7307 410 Gene3D G3DSA:3.30.450.380 38 170 3.3E-25 T 12-10-2018 AFR_01845 3545614f8a2f231ff24f439d8d6b7307 410 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 25 362 8.4E-151 T 12-10-2018 IPR022399 Helicase/secretion neighbourhood ATPase AFR_01845 3545614f8a2f231ff24f439d8d6b7307 410 SUPERFAMILY SSF52540 58 354 8.31E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01845 3545614f8a2f231ff24f439d8d6b7307 410 Pfam PF00437 Type II/IV secretion system protein 77 351 3.4E-68 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFR_27970 7b43c7b561b1d63d31ce10989fb5d93f 853 SUPERFAMILY SSF53706 1 657 3.01E-182 T 12-10-2018 AFR_27970 7b43c7b561b1d63d31ce10989fb5d93f 853 Pfam PF00384 Molybdopterin oxidoreductase 12 385 8.0E-10 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27970 7b43c7b561b1d63d31ce10989fb5d93f 853 Gene3D G3DSA:3.40.50.740 306 480 1.0E-57 T 12-10-2018 AFR_27970 7b43c7b561b1d63d31ce10989fb5d93f 853 Gene3D G3DSA:2.40.40.20 647 826 2.0E-59 T 12-10-2018 AFR_27970 7b43c7b561b1d63d31ce10989fb5d93f 853 Pfam PF01568 Molydopterin dinucleotide binding domain 702 811 1.3E-13 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFR_27970 7b43c7b561b1d63d31ce10989fb5d93f 853 SUPERFAMILY SSF50692 637 826 4.07E-35 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFR_27970 7b43c7b561b1d63d31ce10989fb5d93f 853 Gene3D G3DSA:3.40.228.10 551 646 1.5E-22 T 12-10-2018 AFR_01080 3c1310d21d89a192a7f6b92bf9cab294 302 SUPERFAMILY SSF51430 3 298 1.05E-87 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_01080 3c1310d21d89a192a7f6b92bf9cab294 302 Pfam PF00248 Aldo/keto reductase family 3 293 1.4E-70 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_01080 3c1310d21d89a192a7f6b92bf9cab294 302 Gene3D G3DSA:3.20.20.100 1 301 9.3E-106 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_00685 406bf14244761caa34c82c764f1be8e6 413 SUPERFAMILY SSF52440 2 101 1.02E-30 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_00685 406bf14244761caa34c82c764f1be8e6 413 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 SUPERFAMILY SSF56059 102 309 8.13E-52 T 12-10-2018 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 SMART SM01210 318 407 1.1E-37 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 1.7E-61 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 403 1.9E-25 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 SMART SM01209 101 283 2.6E-106 T 12-10-2018 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 407 8.5E-138 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 SUPERFAMILY SSF51246 317 406 3.06E-23 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Gene3D G3DSA:3.90.600.10 318 404 2.6E-26 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Gene3D G3DSA:3.30.1490.20 121 178 5.8E-14 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 407 39.436 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Gene3D G3DSA:3.30.470.20 179 315 1.5E-50 T 12-10-2018 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Gene3D G3DSA:3.40.50.20 1 93 8.6E-32 T 12-10-2018 AFR_00685 406bf14244761caa34c82c764f1be8e6 413 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 3.4E-30 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_05280 49be31be58bccb1daa2327507a449ee5 603 SUPERFAMILY SSF53448 153 413 1.69E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05280 49be31be58bccb1daa2327507a449ee5 603 Gene3D G3DSA:3.90.550.10 144 369 2.0E-49 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05280 49be31be58bccb1daa2327507a449ee5 603 Pfam PF13506 Glycosyl transferase family 21 217 384 3.7E-18 T 12-10-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 AFR_21935 276aad479ca904f62f7844a940f6ec20 299 Gene3D G3DSA:3.40.50.300 1 236 5.5E-62 T 12-10-2018 AFR_21935 276aad479ca904f62f7844a940f6ec20 299 SMART SM00382 26 205 5.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21935 276aad479ca904f62f7844a940f6ec20 299 Pfam PF00005 ABC transporter 18 157 5.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_21935 276aad479ca904f62f7844a940f6ec20 299 SUPERFAMILY SSF52540 2 219 2.76E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27810 6dc596e448e5625400b9e07939777d46 179 SUPERFAMILY SSF51735 7 177 5.92E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_27810 6dc596e448e5625400b9e07939777d46 179 Gene3D G3DSA:3.40.50.720 1 178 7.4E-28 T 12-10-2018 AFR_27810 6dc596e448e5625400b9e07939777d46 179 Pfam PF13460 NAD(P)H-binding 7 168 1.7E-28 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_09895 0c61796435f36f35af89fb23380880fe 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 259 272 2.7E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_09895 0c61796435f36f35af89fb23380880fe 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 434 450 2.7E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_09895 0c61796435f36f35af89fb23380880fe 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 222 241 2.7E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_09895 0c61796435f36f35af89fb23380880fe 1098 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 227 238 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_09895 0c61796435f36f35af89fb23380880fe 1098 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 435 445 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_09895 0c61796435f36f35af89fb23380880fe 1098 Gene3D G3DSA:3.40.50.200 197 496 2.5E-92 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_09895 0c61796435f36f35af89fb23380880fe 1098 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 263 273 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_09895 0c61796435f36f35af89fb23380880fe 1098 SUPERFAMILY SSF52743 204 493 4.84E-79 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_09895 0c61796435f36f35af89fb23380880fe 1098 Pfam PF00082 Subtilase family 222 484 1.9E-56 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_02455 4857971c51a520f54edfc921c549572f 361 Gene3D G3DSA:3.40.50.2300 180 317 2.6E-77 T 12-10-2018 AFR_02455 4857971c51a520f54edfc921c549572f 361 SUPERFAMILY SSF53822 70 354 3.81E-71 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_02455 4857971c51a520f54edfc921c549572f 361 Pfam PF13407 Periplasmic binding protein domain 83 335 2.1E-50 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_02455 4857971c51a520f54edfc921c549572f 361 Gene3D G3DSA:3.40.50.2300 75 334 2.6E-77 T 12-10-2018 AFR_05135 c90b5332c61a83e19e8d64a53f475caf 446 Pfam PF09423 PhoD-like phosphatase 56 383 6.7E-101 T 12-10-2018 IPR018946 Alkaline phosphatase D-related AFR_05135 c90b5332c61a83e19e8d64a53f475caf 446 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 3 43 2.2E-10 T 12-10-2018 IPR032093 Phospholipase D, N-terminal AFR_05135 c90b5332c61a83e19e8d64a53f475caf 446 Gene3D G3DSA:3.60.21.70 48 427 1.1E-129 T 12-10-2018 IPR038607 PhoD-like superfamily AFR_05135 c90b5332c61a83e19e8d64a53f475caf 446 SUPERFAMILY SSF56300 50 384 1.94E-33 T 12-10-2018 AFR_05135 c90b5332c61a83e19e8d64a53f475caf 446 Gene3D G3DSA:2.60.40.380 1 46 1.3E-12 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 AFR_26630 23a072ef8216c197443591830b4d93cf 412 SUPERFAMILY SSF52374 32 334 1.47E-62 T 12-10-2018 AFR_26630 23a072ef8216c197443591830b4d93cf 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 3 412 4.4E-191 T 12-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 AFR_26630 23a072ef8216c197443591830b4d93cf 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 52.843 T 12-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 AFR_26630 23a072ef8216c197443591830b4d93cf 412 Gene3D G3DSA:3.40.50.620 1 329 4.0E-94 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_26630 23a072ef8216c197443591830b4d93cf 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 35 335 7.3E-78 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AFR_26630 23a072ef8216c197443591830b4d93cf 412 Gene3D G3DSA:1.20.120.640 330 412 6.2E-23 T 12-10-2018 AFR_26630 23a072ef8216c197443591830b4d93cf 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 5.5E-19 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_26630 23a072ef8216c197443591830b4d93cf 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 5.5E-19 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_26630 23a072ef8216c197443591830b4d93cf 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 5.5E-19 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_26630 23a072ef8216c197443591830b4d93cf 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 5.5E-19 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 SUPERFAMILY SSF55073 364 518 4.71E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 SMART SM00267 348 520 1.4E-46 T 12-10-2018 IPR000160 GGDEF domain AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 Pfam PF00990 Diguanylate cyclase, GGDEF domain 359 516 1.7E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 Gene3D G3DSA:1.25.40.10 217 355 6.8E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 Gene3D G3DSA:1.25.40.10 73 199 2.1E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 357 517 8.4E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 Gene3D G3DSA:3.30.70.270 356 520 2.6E-48 T 12-10-2018 AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 SUPERFAMILY SSF48452 81 180 8.73E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18910 1037b842ac732022e07d9f7fdfb9afae 525 SUPERFAMILY SSF48452 254 363 4.56E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 1.4E-36 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 SUPERFAMILY SSF52440 2 112 2.59E-44 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_39385 b5230d8ed9b93491d0945539653a9522 581 Gene3D G3DSA:3.30.470.130 1 444 1.4E-177 T 12-10-2018 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 SUPERFAMILY SSF51230 508 580 3.01E-19 T 12-10-2018 IPR011053 Single hybrid motif AFR_39385 b5230d8ed9b93491d0945539653a9522 581 SUPERFAMILY SSF56059 82 328 3.18E-59 T 12-10-2018 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 1.0E-76 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 SUPERFAMILY SSF51246 328 443 7.32E-38 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 SMART SM00878 334 440 2.6E-53 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 Pfam PF00364 Biotin-requiring enzyme 515 580 2.6E-18 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_39385 b5230d8ed9b93491d0945539653a9522 581 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 2.4E-41 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 537 554 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_39385 b5230d8ed9b93491d0945539653a9522 581 Gene3D G3DSA:2.40.50.100 506 581 4.0E-21 T 12-10-2018 AFR_05035 611b3b6ee50f7e5cc1eac38b11881e4b 308 SUPERFAMILY SSF161098 90 294 1.1E-14 T 12-10-2018 IPR035906 MetI-like superfamily AFR_05035 611b3b6ee50f7e5cc1eac38b11881e4b 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 3.3E-35 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_05035 611b3b6ee50f7e5cc1eac38b11881e4b 308 Gene3D G3DSA:1.10.3720.10 85 302 2.2E-18 T 12-10-2018 IPR035906 MetI-like superfamily AFR_00265 b4d3254c6b2c262f753ec5d10a7049ee 252 SUPERFAMILY SSF49879 132 250 2.49E-30 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 AFR_00265 b4d3254c6b2c262f753ec5d10a7049ee 252 Gene3D G3DSA:3.30.2320.60 1 126 4.6E-42 T 12-10-2018 AFR_00265 b4d3254c6b2c262f753ec5d10a7049ee 252 Pfam PF12401 Protein of unknown function (DUF2662) 4 117 5.3E-39 T 12-10-2018 IPR022128 Domain of unknown function DUF3662 AFR_00265 b4d3254c6b2c262f753ec5d10a7049ee 252 Gene3D G3DSA:2.60.200.20 142 251 7.1E-31 T 12-10-2018 AFR_00265 b4d3254c6b2c262f753ec5d10a7049ee 252 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 168 249 1.4E-20 T 12-10-2018 IPR032030 YscD, cytoplasmic domain AFR_00265 b4d3254c6b2c262f753ec5d10a7049ee 252 SMART SM00240 178 228 6.6E-16 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFR_31545 8621c97bcebd6d8887a10f4260db97d0 169 SUPERFAMILY SSF158694 4 165 8.37E-43 T 12-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFR_31545 8621c97bcebd6d8887a10f4260db97d0 169 Pfam PF09349 OHCU decarboxylase 8 162 3.1E-39 T 12-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFR_31545 8621c97bcebd6d8887a10f4260db97d0 169 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 7 165 4.5E-51 T 12-10-2018 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 AFR_31545 8621c97bcebd6d8887a10f4260db97d0 169 Gene3D G3DSA:1.10.3330.10 3 167 1.4E-52 T 12-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 Gene3D G3DSA:1.20.200.10 126 454 4.2E-169 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 Pfam PF14698 Argininosuccinate lyase C-terminal 370 437 3.3E-23 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 ProSitePatterns PS00163 Fumarate lyases signature. 282 291 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00149 Fumarate lyase superfamily signature 282 298 2.8E-24 T 12-10-2018 IPR000362 Fumarate lyase family AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00149 Fumarate lyase superfamily signature 109 127 2.8E-24 T 12-10-2018 IPR000362 Fumarate lyase family AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00149 Fumarate lyase superfamily signature 238 265 2.8E-24 T 12-10-2018 IPR000362 Fumarate lyase family AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00149 Fumarate lyase superfamily signature 154 172 2.8E-24 T 12-10-2018 IPR000362 Fumarate lyase family AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 Gene3D G3DSA:1.10.40.30 367 439 4.2E-169 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 SUPERFAMILY SSF48557 13 463 2.83E-133 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 462 1.9E-168 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 Pfam PF00206 Lyase 19 307 7.8E-63 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00145 Argininosuccinate lyase family signature 238 262 1.5E-55 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00145 Argininosuccinate lyase family signature 317 336 1.5E-55 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00145 Argininosuccinate lyase family signature 200 216 1.5E-55 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00145 Argininosuccinate lyase family signature 149 169 1.5E-55 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00145 Argininosuccinate lyase family signature 108 130 1.5E-55 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 PRINTS PR00145 Argininosuccinate lyase family signature 282 298 1.5E-55 T 12-10-2018 AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 Gene3D G3DSA:1.10.275.10 32 236 4.2E-169 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_30205 4c98ac3016c96ccacdbffbadcc452a02 476 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 460 39.946 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 SUPERFAMILY SSF46785 3 124 6.72E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 2.8E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 2.8E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 2.8E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 Gene3D G3DSA:3.30.530.20 109 235 4.2E-34 T 12-10-2018 IPR023393 START-like domain superfamily AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 SUPERFAMILY SSF55961 99 238 3.11E-37 T 12-10-2018 AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 118 233 8.1E-21 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 SMART SM00418 3 78 6.0E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 Pfam PF12840 Helix-turn-helix domain 3 62 1.3E-14 T 12-10-2018 AFR_06905 4660be0cd86deb87c4be858e0b8c7b25 247 Gene3D G3DSA:1.10.10.10 3 106 1.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26740 8d402840e88c225e5fba4c36a64db88e 290 Gene3D G3DSA:3.20.20.410 1 290 6.4E-86 T 12-10-2018 IPR036520 UPF0759 superfamily AFR_26740 8d402840e88c225e5fba4c36a64db88e 290 Pfam PF01904 Protein of unknown function DUF72 22 286 1.3E-61 T 12-10-2018 IPR002763 Protein of unknown function DUF72 AFR_26740 8d402840e88c225e5fba4c36a64db88e 290 SUPERFAMILY SSF117396 2 289 9.81E-71 T 12-10-2018 IPR036520 UPF0759 superfamily AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 Gene3D G3DSA:3.30.450.40 263 417 4.8E-13 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 SUPERFAMILY SSF55874 38 135 2.07E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 SUPERFAMILY SSF81606 451 653 5.49E-7 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 Gene3D G3DSA:3.30.565.10 2 132 5.6E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 SMART SM00331 438 654 4.2E-31 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 Pfam PF13581 Histidine kinase-like ATPase domain 9 124 3.9E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 SUPERFAMILY SSF55781 265 418 1.21E-11 T 12-10-2018 AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 466 653 1.1E-35 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01290 e4810fc3029eedbc6ae601295891b1db 657 Gene3D G3DSA:3.60.40.10 434 654 3.8E-48 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27870 50478e9cb848d15c50ce47cf2cf5480d 186 Pfam PF13302 Acetyltransferase (GNAT) domain 16 157 9.3E-22 T 12-10-2018 IPR000182 GNAT domain AFR_27870 50478e9cb848d15c50ce47cf2cf5480d 186 SUPERFAMILY SSF55729 9 181 3.19E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_27870 50478e9cb848d15c50ce47cf2cf5480d 186 Gene3D G3DSA:3.40.630.30 4 186 1.6E-41 T 12-10-2018 AFR_38900 79627804826927d23b47af728d1bcf60 401 Gene3D G3DSA:1.20.140.10 245 400 4.4E-39 T 12-10-2018 AFR_38900 79627804826927d23b47af728d1bcf60 401 SUPERFAMILY SSF56645 1 257 3.66E-61 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_38900 79627804826927d23b47af728d1bcf60 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 232 2.6E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_38900 79627804826927d23b47af728d1bcf60 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 394 2.1E-35 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_38900 79627804826927d23b47af728d1bcf60 401 SUPERFAMILY SSF47203 242 399 4.83E-44 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_38900 79627804826927d23b47af728d1bcf60 401 Gene3D G3DSA:1.10.540.10 1 128 1.8E-44 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_38900 79627804826927d23b47af728d1bcf60 401 Gene3D G3DSA:2.40.110.10 129 244 3.3E-47 T 12-10-2018 AFR_38900 79627804826927d23b47af728d1bcf60 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 125 8.6E-12 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_04695 870d17da74c368ef0b154d842724e88d 344 Gene3D G3DSA:3.50.50.60 6 326 2.9E-70 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_04695 870d17da74c368ef0b154d842724e88d 344 Pfam PF01266 FAD dependent oxidoreductase 6 325 1.1E-50 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_04695 870d17da74c368ef0b154d842724e88d 344 SUPERFAMILY SSF51905 6 343 1.68E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_04695 870d17da74c368ef0b154d842724e88d 344 Gene3D G3DSA:3.30.9.10 91 288 2.9E-70 T 12-10-2018 AFR_04695 870d17da74c368ef0b154d842724e88d 344 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 6 327 2.3E-86 T 12-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 AFR_04695 870d17da74c368ef0b154d842724e88d 344 SUPERFAMILY SSF54373 199 288 3.01E-15 T 12-10-2018 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 137 158 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 Gene3D G3DSA:3.90.180.10 13 319 4.9E-112 T 12-10-2018 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 84 5.1E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 SMART SM00829 7 319 6.8E-58 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 319 1.0E-131 T 12-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 SUPERFAMILY SSF51735 108 282 5.54E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 Pfam PF00107 Zinc-binding dehydrogenase 148 261 2.0E-27 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 Gene3D G3DSA:3.40.50.720 117 258 4.9E-112 T 12-10-2018 AFR_42310 9f53d7a09c0ac9cc441e6775012a1b19 321 SUPERFAMILY SSF50129 1 137 2.13E-39 T 12-10-2018 IPR011032 GroES-like superfamily AFR_21475 c32e809f03ad08278700b42eb07d3073 316 Pfam PF00589 Phage integrase family 122 296 3.4E-25 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_21475 c32e809f03ad08278700b42eb07d3073 316 SUPERFAMILY SSF56349 8 304 8.24E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_21475 c32e809f03ad08278700b42eb07d3073 316 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 89 1.3E-5 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFR_21475 c32e809f03ad08278700b42eb07d3073 316 Gene3D G3DSA:1.10.443.10 118 304 2.1E-38 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_21475 c32e809f03ad08278700b42eb07d3073 316 Gene3D G3DSA:1.10.150.130 9 100 2.9E-10 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_03020 5eb8b588f1738650f1d0d650c1420726 702 SUPERFAMILY SSF53649 172 548 1.22E-17 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_03020 5eb8b588f1738650f1d0d650c1420726 702 Gene3D G3DSA:3.40.720.10 167 485 6.8E-23 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_03020 5eb8b588f1738650f1d0d650c1420726 702 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 181 452 8.6E-10 T 12-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 AFR_27080 76b639556c00358ece38e1bd70cb7d81 167 Gene3D G3DSA:1.10.10.10 95 157 9.4E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27080 76b639556c00358ece38e1bd70cb7d81 167 Pfam PF04542 Sigma-70 region 2 17 75 1.0E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_27080 76b639556c00358ece38e1bd70cb7d81 167 SUPERFAMILY SSF88946 3 96 1.18E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_27080 76b639556c00358ece38e1bd70cb7d81 167 Pfam PF08281 Sigma-70, region 4 100 151 6.0E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_27080 76b639556c00358ece38e1bd70cb7d81 167 Gene3D G3DSA:1.10.1740.10 1 77 1.4E-9 T 12-10-2018 AFR_27080 76b639556c00358ece38e1bd70cb7d81 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 152 3.2E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_27080 76b639556c00358ece38e1bd70cb7d81 167 SUPERFAMILY SSF88659 96 155 1.73E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_14175 f3eba525c5b396323faaac364c010755 399 Pfam PF16360 GTP-binding GTPase Middle Region 130 215 1.1E-21 T 12-10-2018 IPR032305 GTP-binding protein, middle domain AFR_14175 f3eba525c5b396323faaac364c010755 399 Gene3D G3DSA:3.40.50.300 220 391 7.5E-43 T 12-10-2018 AFR_14175 f3eba525c5b396323faaac364c010755 399 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 21 379 9.3E-125 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFR_14175 f3eba525c5b396323faaac364c010755 399 Pfam PF01926 50S ribosome-binding GTPase 223 340 5.6E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_14175 f3eba525c5b396323faaac364c010755 399 SUPERFAMILY SSF52540 220 386 6.33E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14175 f3eba525c5b396323faaac364c010755 399 Hamap MF_00900 GTPase HflX [hflX]. 43 393 42.642 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFR_14175 f3eba525c5b396323faaac364c010755 399 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 223 243 3.4E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_14175 f3eba525c5b396323faaac364c010755 399 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 244 262 3.4E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_14175 f3eba525c5b396323faaac364c010755 399 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 289 307 3.4E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_14175 f3eba525c5b396323faaac364c010755 399 Pfam PF13167 GTP-binding GTPase N-terminal 41 128 1.4E-31 T 12-10-2018 IPR025121 GTPase HflX, N-terminal AFR_14175 f3eba525c5b396323faaac364c010755 399 Gene3D G3DSA:3.40.50.11060 38 155 1.7E-38 T 12-10-2018 AFR_14175 f3eba525c5b396323faaac364c010755 399 PIRSF PIRSF006809 12 393 6.2E-130 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 Pfam PF00553 Cellulose binding domain 414 512 4.0E-12 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 SMART SM00637 414 512 1.6E-4 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 141 153 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 46 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 SUPERFAMILY SSF49384 410 512 2.72E-11 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 Gene3D G3DSA:3.30.200.20 6 101 1.6E-29 T 12-10-2018 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 SUPERFAMILY SSF56112 13 288 1.25E-71 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 Gene3D G3DSA:2.60.40.290 409 514 2.1E-17 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 Gene3D G3DSA:1.10.510.10 103 282 9.5E-48 T 12-10-2018 AFR_04025 a5b461503a4b9b7adb554cc37ec4f052 572 Pfam PF00069 Protein kinase domain 17 271 5.4E-44 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_22750 623e6ee33066b0be0b362e4c59c0f6b1 200 Gene3D G3DSA:3.40.50.150 2 196 1.8E-30 T 12-10-2018 AFR_22750 623e6ee33066b0be0b362e4c59c0f6b1 200 Pfam PF08241 Methyltransferase domain 49 144 1.5E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_22750 623e6ee33066b0be0b362e4c59c0f6b1 200 SUPERFAMILY SSF53335 11 188 3.5E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_28145 1d1c130dee398ff220fa1860d238719f 500 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 323 479 1.1E-35 T 12-10-2018 IPR000160 GGDEF domain AFR_28145 1d1c130dee398ff220fa1860d238719f 500 SMART SM00267 316 484 1.4E-58 T 12-10-2018 IPR000160 GGDEF domain AFR_28145 1d1c130dee398ff220fa1860d238719f 500 Pfam PF00990 Diguanylate cyclase, GGDEF domain 327 476 7.3E-44 T 12-10-2018 IPR000160 GGDEF domain AFR_28145 1d1c130dee398ff220fa1860d238719f 500 Gene3D G3DSA:3.30.70.270 321 495 5.1E-56 T 12-10-2018 AFR_28145 1d1c130dee398ff220fa1860d238719f 500 SUPERFAMILY SSF55073 332 486 4.51E-47 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_00535 68959a1b9ce6637f7f587ea4bc12a3dd 146 Gene3D G3DSA:1.10.1660.10 5 121 6.2E-23 T 12-10-2018 AFR_00535 68959a1b9ce6637f7f587ea4bc12a3dd 146 Pfam PF13411 MerR HTH family regulatory protein 20 84 1.9E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_00535 68959a1b9ce6637f7f587ea4bc12a3dd 146 SMART SM00422 18 87 1.5E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_00535 68959a1b9ce6637f7f587ea4bc12a3dd 146 SUPERFAMILY SSF46955 20 120 7.33E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_28665 a83516b86d5c09471fba54e85cb346ec 111 SUPERFAMILY SSF54292 2 93 9.83E-24 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_28665 a83516b86d5c09471fba54e85cb346ec 111 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_28665 a83516b86d5c09471fba54e85cb346ec 111 Gene3D G3DSA:3.10.20.30 2 95 1.2E-21 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_28665 a83516b86d5c09471fba54e85cb346ec 111 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 81 1.7E-10 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 SUPERFAMILY SSF49785 337 554 7.23E-49 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 Gene3D G3DSA:2.60.120.260 341 554 1.3E-61 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 SMART SM00939 311 550 2.9E-63 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 SUPERFAMILY SSF53474 21 345 2.13E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 37 298 5.5E-45 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 328 549 1.5E-34 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 33 554 2.2E-86 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 Gene3D G3DSA:3.40.50.1820 31 339 2.6E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28445 12f6a9081c9b7b7d5cc6fd1653040f56 560 Gene3D G3DSA:1.10.3020.10 162 249 2.6E-69 T 12-10-2018 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SUPERFAMILY SSF55785 16 114 1.69E-12 T 12-10-2018 IPR035965 PAS domain superfamily AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Gene3D G3DSA:3.60.40.10 476 694 4.7E-52 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SUPERFAMILY SSF55874 734 817 2.19E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 134 2.3E-10 T 12-10-2018 IPR000014 PAS domain AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Gene3D G3DSA:3.30.450.40 144 317 8.7E-20 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SUPERFAMILY SSF55781 166 321 5.23E-18 T 12-10-2018 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SUPERFAMILY SSF55781 407 463 4.36E-10 T 12-10-2018 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SMART SM00065 163 318 3.3E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SMART SM00065 319 462 0.18 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Pfam PF13185 GAF domain 163 309 4.1E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Pfam PF13581 Histidine kinase-like ATPase domain 707 817 6.1E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SMART SM00091 11 78 8.6E-5 T 12-10-2018 IPR000014 PAS domain AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 SMART SM00331 483 695 6.1E-32 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Gene3D G3DSA:3.30.450.40 327 466 2.0E-12 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Gene3D G3DSA:3.30.565.10 698 823 2.4E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Pfam PF13426 PAS domain 21 112 1.5E-7 T 12-10-2018 IPR000014 PAS domain AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 510 694 3.6E-40 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_07650 9b5d394248d76fadbbb6b2a2c231c9b8 824 Gene3D G3DSA:3.30.450.20 15 143 4.9E-14 T 12-10-2018 AFR_15970 efe7e8af827a6986ae5cdbd7a234d6ad 342 SUPERFAMILY SSF52540 36 255 3.59E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15970 efe7e8af827a6986ae5cdbd7a234d6ad 342 Gene3D G3DSA:3.40.50.300 15 279 9.5E-59 T 12-10-2018 AFR_15970 efe7e8af827a6986ae5cdbd7a234d6ad 342 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_15970 efe7e8af827a6986ae5cdbd7a234d6ad 342 SMART SM00382 54 334 1.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_15970 efe7e8af827a6986ae5cdbd7a234d6ad 342 Pfam PF00005 ABC transporter 45 189 2.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 Gene3D G3DSA:3.20.20.80 3 440 4.5E-164 T 12-10-2018 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 344 352 7.6E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 279 293 7.6E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 376 7.6E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 422 7.6E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 403 7.6E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 Pfam PF00232 Glycosyl hydrolase family 1 7 435 1.7E-145 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 SUPERFAMILY SSF51445 6 438 1.39E-157 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_14430 c9893c6e8cb4f245d7893b76ec3c1d55 440 TIGRFAM TIGR03356 BGL: beta-galactosidase 7 431 6.6E-177 T 12-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 AFR_11055 4de4295fe45a8c6e35382270b92095c3 342 TIGRFAM TIGR00109 hemH: ferrochelatase 6 309 2.5E-42 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFR_11055 4de4295fe45a8c6e35382270b92095c3 342 SUPERFAMILY SSF53800 3 336 1.64E-82 T 12-10-2018 AFR_11055 4de4295fe45a8c6e35382270b92095c3 342 Gene3D G3DSA:3.40.50.1400 146 292 2.9E-119 T 12-10-2018 AFR_11055 4de4295fe45a8c6e35382270b92095c3 342 ProSitePatterns PS00534 Ferrochelatase signature. 176 198 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFR_11055 4de4295fe45a8c6e35382270b92095c3 342 Pfam PF00762 Ferrochelatase 4 310 6.1E-96 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFR_11055 4de4295fe45a8c6e35382270b92095c3 342 Gene3D G3DSA:3.40.50.1400 7 307 2.9E-119 T 12-10-2018 AFR_11055 4de4295fe45a8c6e35382270b92095c3 342 Hamap MF_00323 Ferrochelatase [hemH]. 2 311 29.301 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 Gene3D G3DSA:1.10.10.10 1 57 2.4E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.0E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.0E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 SUPERFAMILY SSF100950 74 243 5.02E-29 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 SMART SM01134 72 242 3.6E-59 T 12-10-2018 AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 1.6E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 SUPERFAMILY SSF46785 6 65 4.34E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 SMART SM00420 6 58 3.9E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 Pfam PF00455 DeoR C terminal sensor domain 74 241 2.1E-46 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain AFR_41015 52d362bc154ae26b29b73f88045b2e00 261 Gene3D G3DSA:3.40.50.1360 71 238 4.2E-7 T 12-10-2018 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Pfam PF10410 DnaB-helicase binding domain of primase 379 434 2.6E-15 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 SUPERFAMILY SSF57783 5 100 2.04E-31 T 12-10-2018 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 SMART SM00400 37 91 2.7E-33 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 TIGRFAM TIGR01391 dnaG: DNA primase 6 426 2.5E-111 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Gene3D G3DSA:3.40.1360.10 247 377 2.0E-33 T 12-10-2018 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Pfam PF13662 Toprim domain 266 337 8.0E-16 T 12-10-2018 IPR006171 TOPRIM domain AFR_08170 49c5383945f117ee55eaadd80851ba07 615 SMART SM00493 265 343 8.1E-14 T 12-10-2018 IPR006171 TOPRIM domain AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Gene3D G3DSA:3.90.980.10 114 246 1.2E-37 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily AFR_08170 49c5383945f117ee55eaadd80851ba07 615 SUPERFAMILY SSF56731 120 432 1.96E-92 T 12-10-2018 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Pfam PF08278 DNA primase DnaG DnaB-binding 466 593 3.7E-25 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Pfam PF08275 DNA primase catalytic core, N-terminal domain 130 258 7.5E-38 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Gene3D G3DSA:3.90.580.10 1 102 1.2E-33 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 SMART SM00766 465 594 1.7E-16 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 PIRSF PIRSF002811 2 605 1.0E-138 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Pfam PF01807 CHC2 zinc finger 6 101 5.6E-32 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFR_08170 49c5383945f117ee55eaadd80851ba07 615 Hamap MF_00974 DNA primase [dnaG]. 4 599 25.482 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFR_18860 b8a72b368627908eadd69b60223ee70d 371 Gene3D G3DSA:3.20.20.120 116 349 1.4E-135 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_18860 b8a72b368627908eadd69b60223ee70d 371 SUPERFAMILY SSF54826 1 124 1.17E-31 T 12-10-2018 AFR_18860 b8a72b368627908eadd69b60223ee70d 371 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 40.651 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 AFR_18860 b8a72b368627908eadd69b60223ee70d 371 SMART SM00922 142 235 3.9E-22 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFR_18860 b8a72b368627908eadd69b60223ee70d 371 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 331 4.9E-91 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 AFR_18860 b8a72b368627908eadd69b60223ee70d 371 Gene3D G3DSA:3.30.390.10 6 115 1.4E-135 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFR_18860 b8a72b368627908eadd69b60223ee70d 371 Pfam PF13378 Enolase C-terminal domain-like 152 354 4.2E-47 T 12-10-2018 IPR029065 Enolase C-terminal domain-like AFR_18860 b8a72b368627908eadd69b60223ee70d 371 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 124 6.2E-9 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFR_18860 b8a72b368627908eadd69b60223ee70d 371 SUPERFAMILY SSF51604 114 363 5.11E-64 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_14610 1a44063b416e6712105a644e93c89ada 552 Gene3D G3DSA:3.90.76.10 56 228 3.6E-120 T 12-10-2018 AFR_14610 1a44063b416e6712105a644e93c89ada 552 SUPERFAMILY SSF53850 39 550 2.71E-109 T 12-10-2018 AFR_14610 1a44063b416e6712105a644e93c89ada 552 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 470 2.4E-76 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFR_14610 1a44063b416e6712105a644e93c89ada 552 PIRSF PIRSF002741 1 552 4.4E-82 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFR_14610 1a44063b416e6712105a644e93c89ada 552 Gene3D G3DSA:3.40.190.10 229 539 3.6E-120 T 12-10-2018 AFR_14610 1a44063b416e6712105a644e93c89ada 552 Gene3D G3DSA:3.10.105.10 310 527 3.6E-120 T 12-10-2018 AFR_00715 4d2063621786987ddde9089cc0e69e5d 88 SUPERFAMILY SSF82697 3 75 2.79E-22 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00715 4d2063621786987ddde9089cc0e69e5d 88 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 9.0E-17 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_00715 4d2063621786987ddde9089cc0e69e5d 88 Gene3D G3DSA:3.30.1280.10 2 81 1.9E-25 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00715 4d2063621786987ddde9089cc0e69e5d 88 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 4.1E-16 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_00715 4d2063621786987ddde9089cc0e69e5d 88 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 5.5E-25 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_00715 4d2063621786987ddde9089cc0e69e5d 88 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 20.285 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_36860 1ea1be4dfc9800c6509c95aa910032c0 343 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 235 254 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFR_36860 1ea1be4dfc9800c6509c95aa910032c0 343 Gene3D G3DSA:3.40.718.10 1 341 3.0E-125 T 12-10-2018 AFR_36860 1ea1be4dfc9800c6509c95aa910032c0 343 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 323 2.5E-87 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFR_36860 1ea1be4dfc9800c6509c95aa910032c0 343 SUPERFAMILY SSF53659 3 338 2.69E-106 T 12-10-2018 AFR_36860 1ea1be4dfc9800c6509c95aa910032c0 343 SMART SM01329 3 337 4.1E-157 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 SMART SM00422 3 71 8.9E-25 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 Gene3D G3DSA:1.10.1660.10 1 126 1.8E-32 T 12-10-2018 AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 Pfam PF00376 MerR family regulatory protein 4 40 1.5E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 SUPERFAMILY SSF46955 3 125 9.89E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 Pfam PF09278 MerR, DNA binding 45 106 5.0E-17 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 8.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 8.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 8.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42265 ba0bca5220c3f869a01151b7ec2a34a1 142 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 2 141 4.1E-64 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 AFR_35685 f7c83f1c78dce6d70d46bcf28f033936 448 SMART SM00345 15 74 4.6E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_35685 f7c83f1c78dce6d70d46bcf28f033936 448 Gene3D G3DSA:1.10.10.10 13 87 4.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35685 f7c83f1c78dce6d70d46bcf28f033936 448 Pfam PF00155 Aminotransferase class I and II 149 432 1.5E-21 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_35685 f7c83f1c78dce6d70d46bcf28f033936 448 SUPERFAMILY SSF53383 86 431 2.36E-57 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_35685 f7c83f1c78dce6d70d46bcf28f033936 448 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 8.1E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_35685 f7c83f1c78dce6d70d46bcf28f033936 448 SUPERFAMILY SSF46785 11 82 1.01E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_35685 f7c83f1c78dce6d70d46bcf28f033936 448 Gene3D G3DSA:3.40.640.10 92 431 9.0E-46 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 TIGRFAM TIGR01351 adk: adenylate kinase 4 207 6.7E-61 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 Hamap MF_00235 Adenylate kinase [adk]. 2 209 36.046 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 Pfam PF00406 Adenylate kinase 6 186 1.5E-38 T 12-10-2018 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 SUPERFAMILY SSF57774 123 159 7.78E-11 T 12-10-2018 IPR036193 Adenylate kinase, active site lid domain superfamily GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 Pfam PF05191 Adenylate kinase, active site lid 123 158 4.3E-12 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 SUPERFAMILY SSF52540 2 208 4.51E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 PRINTS PR00094 Adenylate kinase signature 156 171 7.9E-23 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 PRINTS PR00094 Adenylate kinase signature 5 18 7.9E-23 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 PRINTS PR00094 Adenylate kinase signature 33 47 7.9E-23 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 PRINTS PR00094 Adenylate kinase signature 82 98 7.9E-23 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 PRINTS PR00094 Adenylate kinase signature 173 187 7.9E-23 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_30020 1afff1c3af4e56fe7264d3fe19cd4107 217 Gene3D G3DSA:3.40.50.300 2 210 1.5E-68 T 12-10-2018 AFR_08050 c0ae2ef0febacc13fc079f1ee7e0ea94 193 Pfam PF09819 ABC-type cobalt transport system, permease component 10 129 1.0E-39 T 12-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted AFR_08050 c0ae2ef0febacc13fc079f1ee7e0ea94 193 PIRSF PIRSF037394 1 192 4.0E-59 T 12-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted AFR_33740 ea3a781c5973d10339bae25889a90228 515 SUPERFAMILY SSF55486 239 468 9.82E-45 T 12-10-2018 AFR_33740 ea3a781c5973d10339bae25889a90228 515 Pfam PF01433 Peptidase family M1 domain 315 460 5.6E-25 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_33740 ea3a781c5973d10339bae25889a90228 515 Gene3D G3DSA:2.60.40.1730 50 228 6.9E-27 T 12-10-2018 AFR_33740 ea3a781c5973d10339bae25889a90228 515 SUPERFAMILY SSF63737 40 228 5.1E-43 T 12-10-2018 AFR_33740 ea3a781c5973d10339bae25889a90228 515 Gene3D G3DSA:1.10.390.60 255 464 6.4E-35 T 12-10-2018 AFR_33740 ea3a781c5973d10339bae25889a90228 515 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 165 180 2.4E-13 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_33740 ea3a781c5973d10339bae25889a90228 515 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 338 350 2.4E-13 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_33740 ea3a781c5973d10339bae25889a90228 515 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 212 227 2.4E-13 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_33740 ea3a781c5973d10339bae25889a90228 515 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 334 2.4E-13 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_30565 b07028991657f6a9fee7d89d1d0f8c7f 380 Pfam PF13449 Esterase-like activity of phytase 58 347 9.0E-67 T 12-10-2018 IPR027372 Phytase-like domain AFR_30565 b07028991657f6a9fee7d89d1d0f8c7f 380 SUPERFAMILY SSF63829 131 211 3.92E-5 T 12-10-2018 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 SUPERFAMILY SSF158472 73 118 1.07E-10 T 12-10-2018 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 SMART SM00304 70 122 2.0E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 Gene3D G3DSA:1.10.8.500 71 118 1.5E-8 T 12-10-2018 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 SUPERFAMILY SSF47384 106 187 4.12E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 SUPERFAMILY SSF55874 177 348 7.99E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 233 347 8.7E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 Pfam PF00672 HAMP domain 73 117 4.6E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 SMART SM00387 233 348 8.4E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 Gene3D G3DSA:1.10.287.130 119 186 1.6E-20 T 12-10-2018 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 320 7.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 7.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 298 7.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 Pfam PF00512 His Kinase A (phospho-acceptor) domain 124 187 3.5E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 SMART SM00388 123 187 3.0E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_42445 39a1cabedd5f8c2d1e085b80d5e18e98 354 Gene3D G3DSA:3.30.565.10 193 350 6.6E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SMART SM00823 Phosphopantetheine attachment site 969 1038 1.6E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SMART SM00823 Phosphopantetheine attachment site 2031 2100 4.1E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF00668 Condensation domain 14 449 3.2E-81 T 12-10-2018 IPR001242 Condensation domain AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF00668 Condensation domain 1053 1503 4.5E-91 T 12-10-2018 IPR001242 Condensation domain AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF56801 431 982 5.1E-144 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF47336 2024 2097 9.68E-20 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF13193 AMP-binding enzyme C-terminal domain 869 944 1.3E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF13193 AMP-binding enzyme C-terminal domain 1937 2008 9.5E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF52777 195 440 3.56E-56 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF52777 11 210 9.67E-41 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SMART SM00824 Thioesterase 2123 2370 1.2E-4 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 492 885 4.3E-126 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1546 1953 1.7E-128 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.30.559.30 196 447 1.7E-138 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1668 1679 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF52777 1241 1489 1.33E-61 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 ProSitePatterns PS00455 Putative AMP-binding domain signature. 607 618 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:1.10.1200.10 957 1041 4.4E-28 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 ProSitePatterns PS00012 Phosphopantetheine attachment site. 993 1008 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.30.300.30 1923 2021 1.3E-33 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.30.300.30 856 956 1.4E-33 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF53474 2102 2370 8.04E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF00501 AMP-binding enzyme 1525 1929 2.8E-86 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF00501 AMP-binding enzyme 471 861 1.6E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.40.50.1820 2022 2372 2.1E-113 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF56801 1485 2043 2.09E-148 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.30.559.30 1237 1491 1.4E-155 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.30.559.10 18 383 1.7E-138 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF52777 1057 1228 6.89E-46 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.40.50.12780 1517 1921 6.9E-128 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.30.559.10 1055 1429 1.4E-155 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF00975 Thioesterase domain 2121 2356 1.4E-32 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 SUPERFAMILY SSF47336 962 1034 8.11E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Gene3D G3DSA:3.40.50.12780 458 855 2.7E-135 T 12-10-2018 AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF00550 Phosphopantetheine attachment site 2033 2096 5.7E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18550 e2f009bc41c23db0c6a6cb7893bcd79f 2375 Pfam PF00550 Phosphopantetheine attachment site 971 1034 8.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_16460 c6752c34859f271ed51170c35b62499d 466 Gene3D G3DSA:1.20.1740.10 17 460 1.8E-119 T 12-10-2018 AFR_16460 c6752c34859f271ed51170c35b62499d 466 Pfam PF13520 Amino acid permease 22 426 1.6E-55 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_16460 c6752c34859f271ed51170c35b62499d 466 PIRSF PIRSF006060 3 465 5.3E-94 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_32980 57a30c20e079db05ae17e13343151f17 263 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 27 4.2E-8 T 12-10-2018 AFR_32980 57a30c20e079db05ae17e13343151f17 263 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 169 4.2E-8 T 12-10-2018 AFR_32980 57a30c20e079db05ae17e13343151f17 263 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 138 153 4.2E-8 T 12-10-2018 AFR_32980 57a30c20e079db05ae17e13343151f17 263 SUPERFAMILY SSF51905 1 232 7.56E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_32980 57a30c20e079db05ae17e13343151f17 263 Pfam PF01494 FAD binding domain 16 195 1.6E-9 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_32980 57a30c20e079db05ae17e13343151f17 263 Gene3D G3DSA:3.50.50.60 2 196 1.5E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_32980 57a30c20e079db05ae17e13343151f17 263 Gene3D G3DSA:3.30.9.50 40 128 1.5E-40 T 12-10-2018 AFR_29890 b98f11e3da48796360ee5b7f6eabdd01 198 SUPERFAMILY SSF55811 7 180 1.62E-40 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_29890 b98f11e3da48796360ee5b7f6eabdd01 198 Pfam PF00293 NUDIX domain 43 158 1.6E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_29890 b98f11e3da48796360ee5b7f6eabdd01 198 Gene3D G3DSA:3.90.79.10 3 198 2.5E-55 T 12-10-2018 AFR_24480 2e474bf69fa33ab1985367abeaf938be 303 Pfam PF03734 L,D-transpeptidase catalytic domain 167 285 8.3E-16 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_24480 2e474bf69fa33ab1985367abeaf938be 303 Gene3D G3DSA:2.40.440.10 163 299 1.5E-82 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_24480 2e474bf69fa33ab1985367abeaf938be 303 Gene3D G3DSA:2.60.40.3710 69 302 1.5E-82 T 12-10-2018 AFR_24480 2e474bf69fa33ab1985367abeaf938be 303 SUPERFAMILY SSF141523 165 285 2.09E-27 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_02690 6cf449e79931e9b326ef9a08fce918b6 323 Gene3D G3DSA:3.40.50.720 5 303 2.7E-120 T 12-10-2018 AFR_02690 6cf449e79931e9b326ef9a08fce918b6 323 Pfam PF02719 Polysaccharide biosynthesis protein 6 279 6.8E-96 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain AFR_02690 6cf449e79931e9b326ef9a08fce918b6 323 Gene3D G3DSA:3.90.25.30 167 307 2.7E-120 T 12-10-2018 AFR_02690 6cf449e79931e9b326ef9a08fce918b6 323 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 2 318 3.5E-148 T 12-10-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00520+4.2.1.115|MetaCyc: PWY-6143|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 AFR_02690 6cf449e79931e9b326ef9a08fce918b6 323 SUPERFAMILY SSF51735 5 255 3.92E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19790 88671a108923557ad39bc1c83116376e 153 Gene3D G3DSA:3.40.630.30 4 152 1.2E-18 T 12-10-2018 AFR_19790 88671a108923557ad39bc1c83116376e 153 SUPERFAMILY SSF55729 8 143 1.12E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_19790 88671a108923557ad39bc1c83116376e 153 Pfam PF13673 Acetyltransferase (GNAT) domain 55 132 5.4E-9 T 12-10-2018 IPR000182 GNAT domain AFR_25435 824581b7858060d0175ecb0d5b3c0d50 156 Pfam PF00578 AhpC/TSA family 6 129 3.1E-32 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_25435 824581b7858060d0175ecb0d5b3c0d50 156 PIRSF PIRSF000239 2 155 2.8E-18 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_25435 824581b7858060d0175ecb0d5b3c0d50 156 SUPERFAMILY SSF52833 5 152 8.2E-42 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_25435 824581b7858060d0175ecb0d5b3c0d50 156 Gene3D G3DSA:3.40.30.10 2 154 5.8E-44 T 12-10-2018 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Pfam PF05227 CHASE3 domain 24 148 6.6E-11 T 12-10-2018 IPR007891 CHASE3 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Pfam PF00512 His Kinase A (phospho-acceptor) domain 421 489 2.4E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Gene3D G3DSA:3.30.565.10 495 645 4.7E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SUPERFAMILY SSF158472 185 232 1.57E-5 T 12-10-2018 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Gene3D G3DSA:1.20.1440.210 33 147 6.1E-7 T 12-10-2018 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SUPERFAMILY SSF55874 479 644 1.31E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 535 644 1.8E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SMART SM00387 534 645 6.6E-35 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SMART SM00304 185 238 5.4E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SMART SM00388 421 489 1.7E-24 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SUPERFAMILY SSF47384 404 489 1.96E-21 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Gene3D G3DSA:3.30.450.40 239 410 1.2E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Gene3D G3DSA:1.10.287.130 411 491 2.4E-23 T 12-10-2018 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Pfam PF00672 HAMP domain 185 232 1.7E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 Gene3D G3DSA:1.20.1480.50 148 238 1.3E-7 T 12-10-2018 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SUPERFAMILY SSF55781 250 417 3.93E-10 T 12-10-2018 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 SMART SM00065 262 409 8.1E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 606 624 3.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 599 3.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 643 3.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11480 700f1f76c430b5ac225607ffc5971298 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 585 3.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 SUPERFAMILY SSF48452 460 572 1.84E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 SUPERFAMILY SSF48452 389 485 1.0E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Pfam PF13424 Tetratricopeptide repeat 389 452 2.1E-7 T 12-10-2018 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Pfam PF13424 Tetratricopeptide repeat 628 697 2.0E-12 T 12-10-2018 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Gene3D G3DSA:1.25.40.10 593 767 2.1E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Gene3D G3DSA:3.40.50.300 1 159 1.3E-19 T 12-10-2018 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 SUPERFAMILY SSF48452 582 733 6.03E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Pfam PF13374 Tetratricopeptide repeat 506 546 5.8E-6 T 12-10-2018 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Pfam PF13374 Tetratricopeptide repeat 711 752 1.5E-4 T 12-10-2018 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Pfam PF13374 Tetratricopeptide repeat 463 503 8.9E-4 T 12-10-2018 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 Gene3D G3DSA:1.25.40.10 371 592 1.1E-29 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06025 bba45411b37ee16325712618d2a65d9f 806 SUPERFAMILY SSF52540 3 225 6.37E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 SUPERFAMILY SSF56601 56 452 1.33E-59 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 221 447 1.6E-44 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 57 212 4.2E-26 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 Gene3D G3DSA:3.40.710.10 220 449 4.4E-56 T 12-10-2018 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 261 428 3.9E-36 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 Gene3D G3DSA:3.40.710.10 49 123 7.1E-11 T 12-10-2018 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 339 353 1.3E-17 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 324 338 1.3E-17 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 267 289 1.3E-17 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 407 420 1.3E-17 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_41560 d1e469b7ae3a4c60ff0e535cb7179ace 454 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 89 108 1.3E-17 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 Gene3D G3DSA:3.40.50.300 13 252 7.5E-50 T 12-10-2018 AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 Gene3D G3DSA:3.40.50.300 278 500 1.4E-42 T 12-10-2018 AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 SUPERFAMILY SSF52540 284 489 5.97E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 SUPERFAMILY SSF52540 10 232 1.74E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 Pfam PF00005 ABC transporter 285 435 1.4E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 SMART SM00382 292 484 3.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 SMART SM00382 41 230 2.3E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08205 245ae9ff7f49f254f002aa9c1ca203f6 514 Pfam PF00005 ABC transporter 32 182 7.8E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31705 9de795844a824a98769a4e7794f2c8f8 467 Pfam PF05694 56kDa selenium binding protein (SBP56) 5 465 1.8E-196 T 12-10-2018 IPR008826 Selenium-binding protein GO:0008430 AFR_31705 9de795844a824a98769a4e7794f2c8f8 467 SUPERFAMILY SSF75011 79 401 2.22E-23 T 12-10-2018 AFR_31705 9de795844a824a98769a4e7794f2c8f8 467 Gene3D G3DSA:2.130.10.10 216 437 4.1E-9 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_18140 0356dff2129c2994a674b2490c29cbda 732 SMART SM00267 300 464 4.9E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_18140 0356dff2129c2994a674b2490c29cbda 732 Pfam PF00990 Diguanylate cyclase, GGDEF domain 311 459 9.9E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_18140 0356dff2129c2994a674b2490c29cbda 732 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 307 461 9.7E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_18140 0356dff2129c2994a674b2490c29cbda 732 Gene3D G3DSA:3.30.70.270 296 463 1.2E-45 T 12-10-2018 AFR_18140 0356dff2129c2994a674b2490c29cbda 732 Gene3D G3DSA:3.20.20.450 476 726 1.4E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFR_18140 0356dff2129c2994a674b2490c29cbda 732 Pfam PF00563 EAL domain 481 716 8.8E-70 T 12-10-2018 IPR001633 EAL domain AFR_18140 0356dff2129c2994a674b2490c29cbda 732 SMART SM00052 474 721 3.3E-104 T 12-10-2018 IPR001633 EAL domain AFR_18140 0356dff2129c2994a674b2490c29cbda 732 SUPERFAMILY SSF141868 482 723 1.83E-81 T 12-10-2018 IPR035919 EAL domain superfamily AFR_18140 0356dff2129c2994a674b2490c29cbda 732 SUPERFAMILY SSF55073 316 460 5.65E-38 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 Gene3D G3DSA:3.20.20.450 632 887 1.7E-85 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 Pfam PF00563 EAL domain 635 866 3.0E-66 T 12-10-2018 IPR001633 EAL domain AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 Gene3D G3DSA:3.30.70.270 453 631 6.6E-54 T 12-10-2018 AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 SUPERFAMILY SSF55073 464 619 1.8E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 SMART SM00267 448 618 2.1E-54 T 12-10-2018 IPR000160 GGDEF domain AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 SMART SM00091 334 400 4.5E-11 T 12-10-2018 IPR000014 PAS domain AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 331 455 7.9E-19 T 12-10-2018 IPR000014 PAS domain AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 SUPERFAMILY SSF141868 635 877 1.15E-74 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 457 615 3.0E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 SMART SM00052 628 871 2.1E-95 T 12-10-2018 IPR001633 EAL domain AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 SUPERFAMILY SSF55785 327 446 9.87E-20 T 12-10-2018 IPR035965 PAS domain superfamily AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 Gene3D G3DSA:3.30.450.20 327 446 1.5E-20 T 12-10-2018 AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 Pfam PF08447 PAS fold 357 424 1.7E-10 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_02300 53629e15840f74a462dcdfb647e19ce9 892 Pfam PF00990 Diguanylate cyclase, GGDEF domain 459 612 7.2E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_18980 bde3ef01c2715073824720dd3936453e 489 Gene3D G3DSA:1.20.1720.10 25 269 1.8E-37 T 12-10-2018 AFR_18980 bde3ef01c2715073824720dd3936453e 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 412 431 6.5E-6 T 12-10-2018 AFR_18980 bde3ef01c2715073824720dd3936453e 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 6.5E-6 T 12-10-2018 AFR_18980 bde3ef01c2715073824720dd3936453e 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 216 234 6.5E-6 T 12-10-2018 AFR_18980 bde3ef01c2715073824720dd3936453e 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 6.5E-6 T 12-10-2018 AFR_18980 bde3ef01c2715073824720dd3936453e 489 Pfam PF07690 Major Facilitator Superfamily 30 402 2.1E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_18980 bde3ef01c2715073824720dd3936453e 489 SUPERFAMILY SSF103473 15 478 2.22E-42 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_17135 fca992db624b99cc1c09bb566be2502b 183 Pfam PF01872 RibD C-terminal domain 2 174 9.0E-22 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_17135 fca992db624b99cc1c09bb566be2502b 183 Gene3D G3DSA:3.40.430.10 2 178 2.3E-37 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_17135 fca992db624b99cc1c09bb566be2502b 183 SUPERFAMILY SSF53597 1 180 3.4E-28 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 SUPERFAMILY SSF52172 2 160 1.81E-22 T 12-10-2018 IPR011006 CheY-like superfamily AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 SMART SM00421 147 210 3.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 194 6.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 Gene3D G3DSA:1.10.10.10 146 213 1.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 Gene3D G3DSA:3.40.50.2300 1 145 7.7E-25 T 12-10-2018 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 SMART SM00448 1 121 4.4E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 8.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 8.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 8.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 Pfam PF00072 Response regulator receiver domain 3 99 1.7E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26195 d89da13e516c6aec7276c84625ad24a3 213 SUPERFAMILY SSF46894 143 197 1.53E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28525 c96fc5862ae34ed4a0895ae7c0998431 188 Pfam PF01872 RibD C-terminal domain 4 156 1.5E-22 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_28525 c96fc5862ae34ed4a0895ae7c0998431 188 Gene3D G3DSA:3.40.430.10 1 176 5.2E-41 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_28525 c96fc5862ae34ed4a0895ae7c0998431 188 SUPERFAMILY SSF53597 4 172 1.26E-27 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_07875 42047dae4471e22951aa0f01b54cb257 563 ProSitePatterns PS00211 ABC transporters family signature. 462 476 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07875 42047dae4471e22951aa0f01b54cb257 563 Pfam PF00664 ABC transporter transmembrane region 22 289 3.3E-20 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_07875 42047dae4471e22951aa0f01b54cb257 563 SUPERFAMILY SSF90123 9 313 1.83E-48 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_07875 42047dae4471e22951aa0f01b54cb257 563 SUPERFAMILY SSF52540 340 561 3.22E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07875 42047dae4471e22951aa0f01b54cb257 563 Gene3D G3DSA:3.40.50.300 335 563 4.4E-45 T 12-10-2018 AFR_07875 42047dae4471e22951aa0f01b54cb257 563 Pfam PF00005 ABC transporter 346 489 1.7E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_07875 42047dae4471e22951aa0f01b54cb257 563 Gene3D G3DSA:1.20.1560.10 2 316 2.0E-47 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_19020 49bc3ce052812d642ba980d4fb49a8d4 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 151 4.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19020 49bc3ce052812d642ba980d4fb49a8d4 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 353 372 4.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19020 49bc3ce052812d642ba980d4fb49a8d4 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 374 391 4.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19020 49bc3ce052812d642ba980d4fb49a8d4 442 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 222 4.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19020 49bc3ce052812d642ba980d4fb49a8d4 442 SUPERFAMILY SSF51735 130 441 5.12E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19020 49bc3ce052812d642ba980d4fb49a8d4 442 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 293 387 1.2E-9 T 12-10-2018 AFR_19020 49bc3ce052812d642ba980d4fb49a8d4 442 Pfam PF00106 short chain dehydrogenase 134 222 9.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02295 610b4598fa858c89f671ef2c6cd68875 190 Gene3D G3DSA:1.10.10.60 3 47 1.3E-15 T 12-10-2018 AFR_02295 610b4598fa858c89f671ef2c6cd68875 190 SUPERFAMILY SSF46689 5 64 4.14E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_02295 610b4598fa858c89f671ef2c6cd68875 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 68 178 5.9E-28 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_02295 610b4598fa858c89f671ef2c6cd68875 190 Gene3D G3DSA:1.10.357.10 50 186 5.9E-32 T 12-10-2018 AFR_02295 610b4598fa858c89f671ef2c6cd68875 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_02295 610b4598fa858c89f671ef2c6cd68875 190 SUPERFAMILY SSF48498 68 184 2.34E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02295 610b4598fa858c89f671ef2c6cd68875 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 56 1.0E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 Gene3D G3DSA:3.40.50.12740 5 216 2.2E-63 T 12-10-2018 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 Pfam PF00072 Response regulator receiver domain 7 121 1.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 SMART SM00448 5 120 2.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 9.9E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 SUPERFAMILY SSF46894 139 216 2.38E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 SUPERFAMILY SSF52172 4 162 1.38E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28770 b69364f2ad3279ada704c8bfea42b3b8 220 SMART SM00421 153 210 6.0E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16815 5570c3c2fff47099445e75adaf25a172 359 Pfam PF13377 Periplasmic binding protein-like domain 169 326 4.6E-32 T 12-10-2018 AFR_16815 5570c3c2fff47099445e75adaf25a172 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 49 1.3E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_16815 5570c3c2fff47099445e75adaf25a172 359 Gene3D G3DSA:3.40.50.2300 67 297 1.0E-63 T 12-10-2018 AFR_16815 5570c3c2fff47099445e75adaf25a172 359 Gene3D G3DSA:1.10.260.40 1 48 1.2E-16 T 12-10-2018 AFR_16815 5570c3c2fff47099445e75adaf25a172 359 SUPERFAMILY SSF53822 66 328 1.81E-60 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_16815 5570c3c2fff47099445e75adaf25a172 359 Gene3D G3DSA:3.40.50.2300 161 286 1.0E-63 T 12-10-2018 AFR_16815 5570c3c2fff47099445e75adaf25a172 359 SUPERFAMILY SSF47413 4 51 3.84E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_16815 5570c3c2fff47099445e75adaf25a172 359 SMART SM00354 4 76 1.1E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 Pfam PF00672 HAMP domain 225 274 3.7E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 347 507 9.9E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 SUPERFAMILY SSF58104 245 538 5.89E-61 T 12-10-2018 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 412 441 1.3E-24 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 306 335 1.3E-24 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 75 90 1.3E-24 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 29 54 1.3E-24 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 460 489 1.3E-24 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 410 1.3E-24 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 Gene3D G3DSA:1.10.287.950 225 540 3.8E-63 T 12-10-2018 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 SMART SM00283 285 539 1.5E-47 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 SMART SM00304 225 277 4.3E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_15465 6ad3dc7354315116f9cc25a5fb5a9185 540 Pfam PF12729 Four helix bundle sensory module for signal transduction 21 198 5.1E-17 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_11670 e3b834faf2fdd91f2dd73e603dc391dc 274 Pfam PF00561 alpha/beta hydrolase fold 22 254 8.1E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11670 e3b834faf2fdd91f2dd73e603dc391dc 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.2E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11670 e3b834faf2fdd91f2dd73e603dc391dc 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 1.2E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11670 e3b834faf2fdd91f2dd73e603dc391dc 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.2E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11670 e3b834faf2fdd91f2dd73e603dc391dc 274 SUPERFAMILY SSF53474 1 273 5.59E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11670 e3b834faf2fdd91f2dd73e603dc391dc 274 Gene3D G3DSA:3.40.50.1820 1 273 3.6E-86 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_27465 9695d7370fa2e1bf781291f49df99990 568 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 373 383 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 SUPERFAMILY SSF54373 252 344 5.49E-7 T 12-10-2018 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 7.7E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 7.7E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 7.7E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 338 344 7.7E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 7.7E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 368 380 7.7E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 Gene3D G3DSA:3.50.50.60 24 387 5.1E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27465 9695d7370fa2e1bf781291f49df99990 568 SUPERFAMILY SSF51905 21 395 1.46E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27465 9695d7370fa2e1bf781291f49df99990 568 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 402 525 1.4E-31 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 Pfam PF01266 FAD dependent oxidoreductase 24 374 4.6E-54 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 Gene3D G3DSA:1.10.8.870 412 554 8.1E-30 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_27465 9695d7370fa2e1bf781291f49df99990 568 Gene3D G3DSA:3.30.9.10 102 345 5.1E-128 T 12-10-2018 AFR_26340 92e2c0d169bccfb54e6446df6e0cf9a2 315 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 22 49 1.4E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFR_26340 92e2c0d169bccfb54e6446df6e0cf9a2 315 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 121 1.4E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFR_26340 92e2c0d169bccfb54e6446df6e0cf9a2 315 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 121 147 1.4E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFR_26340 92e2c0d169bccfb54e6446df6e0cf9a2 315 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 171 199 1.4E-34 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFR_26340 92e2c0d169bccfb54e6446df6e0cf9a2 315 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 23 244 2.0E-55 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFR_26340 92e2c0d169bccfb54e6446df6e0cf9a2 315 Pfam PF00902 Sec-independent protein translocase protein (TatC) 25 237 9.6E-56 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFR_26340 92e2c0d169bccfb54e6446df6e0cf9a2 315 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 14 256 14.618 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFR_22720 fb3763dcff8577470bc438d820edcf37 387 Pfam PF13229 Right handed beta helix region 162 303 2.0E-12 T 12-10-2018 IPR039448 Right handed beta helix domain AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SUPERFAMILY SSF51126 103 364 1.63E-36 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_22720 fb3763dcff8577470bc438d820edcf37 387 Gene3D G3DSA:2.160.20.10 103 374 2.1E-33 T 12-10-2018 IPR012334 Pectin lyase fold AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SMART SM00710 261 283 33.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SMART SM00710 285 307 1200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SMART SM00710 311 333 1700.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SMART SM00710 339 362 4500.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SMART SM00710 171 192 5400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SMART SM00710 193 215 1600.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22720 fb3763dcff8577470bc438d820edcf37 387 SMART SM00710 217 245 0.94 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 7.6E-47 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 Gene3D G3DSA:3.30.860.10 1 93 5.5E-40 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 PIRSF PIRSF002144 1 93 7.0E-32 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 Pfam PF00203 Ribosomal protein S19 3 83 5.6E-36 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 SUPERFAMILY SSF54570 3 85 2.88E-35 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.341 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04525 3910da3866c5d3ebab8c870b29c726fa 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_06260 6139735f22515dda72ef674711878194 448 Gene3D G3DSA:1.50.10.10 3 435 4.6E-110 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_06260 6139735f22515dda72ef674711878194 448 SUPERFAMILY SSF48208 13 436 4.42E-69 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 Gene3D G3DSA:1.10.1050.10 6 202 1.7E-61 T 12-10-2018 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 SMART SM00363 91 152 2.4E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 Pfam PF01479 S4 domain 92 138 9.2E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 202 28.76 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 SUPERFAMILY SSF55174 5 202 6.54E-55 T 12-10-2018 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 SMART SM01390 2 90 9.7E-36 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 4 90 4.6E-22 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 Gene3D G3DSA:3.10.290.10 90 187 1.7E-61 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFR_10255 de548994bd4c506bea8e0844ce93d70a 202 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 202 1.8E-60 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 SUPERFAMILY SSF55073 331 485 2.04E-39 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 Pfam PF00563 EAL domain 500 724 1.0E-47 T 12-10-2018 IPR001633 EAL domain AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 Gene3D G3DSA:3.20.20.450 496 740 6.3E-62 T 12-10-2018 IPR035919 EAL domain superfamily AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 SMART SM00052 494 731 2.0E-52 T 12-10-2018 IPR001633 EAL domain AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 SMART SM00267 315 484 5.7E-53 T 12-10-2018 IPR000160 GGDEF domain AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 SUPERFAMILY SSF141868 499 737 1.44E-56 T 12-10-2018 IPR035919 EAL domain superfamily AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 Pfam PF00990 Diguanylate cyclase, GGDEF domain 326 479 1.7E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 322 484 1.1E-30 T 12-10-2018 IPR000160 GGDEF domain AFR_33060 9191b2bfb25ade33dead204ea7d5fd15 750 Gene3D G3DSA:3.30.70.270 324 495 9.2E-48 T 12-10-2018 AFR_01545 1b9464fda2ff675fac7e359e68c865ea 118 Gene3D G3DSA:1.10.10.10 17 110 5.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01545 1b9464fda2ff675fac7e359e68c865ea 118 Pfam PF13601 Winged helix DNA-binding domain 27 108 2.6E-25 T 12-10-2018 IPR027395 Winged helix DNA-binding domain AFR_01545 1b9464fda2ff675fac7e359e68c865ea 118 SUPERFAMILY SSF46785 25 107 8.98E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19675 ba549e98123d89e7ed565b1362b9d433 274 Gene3D G3DSA:3.40.50.150 45 245 4.8E-27 T 12-10-2018 AFR_19675 ba549e98123d89e7ed565b1362b9d433 274 SUPERFAMILY SSF53335 40 251 2.5E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_19675 ba549e98123d89e7ed565b1362b9d433 274 Pfam PF13649 Methyltransferase domain 63 152 8.5E-11 T 12-10-2018 AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 Gene3D G3DSA:3.40.50.720 7 260 1.2E-70 T 12-10-2018 AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 SUPERFAMILY SSF51735 15 257 3.8E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11960 1c0cbec10383f8225fb37e4af4e26876 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 256 1.3E-47 T 12-10-2018 AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 Pfam PF00990 Diguanylate cyclase, GGDEF domain 315 468 3.7E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 SMART SM00052 485 730 4.3E-110 T 12-10-2018 IPR001633 EAL domain AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 SUPERFAMILY SSF141868 491 737 3.01E-87 T 12-10-2018 IPR035919 EAL domain superfamily AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 SUPERFAMILY SSF55781 9 143 3.34E-5 T 12-10-2018 AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 Pfam PF00563 EAL domain 491 725 2.0E-74 T 12-10-2018 IPR001633 EAL domain AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 SUPERFAMILY SSF55073 321 477 7.14E-47 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 Gene3D G3DSA:3.20.20.450 488 737 3.9E-98 T 12-10-2018 IPR035919 EAL domain superfamily AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 Gene3D G3DSA:3.30.450.40 152 314 6.7E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 314 474 4.3E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 Gene3D G3DSA:3.30.70.270 315 487 6.5E-56 T 12-10-2018 AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 SUPERFAMILY SSF55781 159 310 2.13E-7 T 12-10-2018 AFR_41715 9dadd8b5a6cdfb79a636e9cef73dadd0 744 SMART SM00267 302 475 2.8E-54 T 12-10-2018 IPR000160 GGDEF domain AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Gene3D G3DSA:3.30.10.20 499 560 4.8E-10 T 12-10-2018 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Gene3D G3DSA:3.30.200.20 1 96 4.4E-33 T 12-10-2018 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Gene3D G3DSA:1.10.510.10 98 284 6.5E-55 T 12-10-2018 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 SMART SM00220 12 276 1.1E-65 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 SMART SM00740 430 495 6.5E-5 T 12-10-2018 IPR005543 PASTA domain AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 SMART SM00740 496 560 1.2E-4 T 12-10-2018 IPR005543 PASTA domain AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 SMART SM00740 362 429 2.4E-7 T 12-10-2018 IPR005543 PASTA domain AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Pfam PF03793 PASTA domain 501 558 2.2E-8 T 12-10-2018 IPR005543 PASTA domain AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Pfam PF03793 PASTA domain 440 494 5.0E-7 T 12-10-2018 IPR005543 PASTA domain AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Pfam PF03793 PASTA domain 368 427 1.3E-8 T 12-10-2018 IPR005543 PASTA domain AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Gene3D G3DSA:3.30.10.20 435 497 2.8E-12 T 12-10-2018 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Pfam PF00069 Protein kinase domain 12 269 5.0E-52 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 Gene3D G3DSA:3.30.10.20 363 429 8.1E-12 T 12-10-2018 AFR_00295 8ff7a3eedfd138ba2d1cfe0054f932a4 597 SUPERFAMILY SSF56112 9 285 4.18E-76 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 SMART SM01092 182 284 2.0E-26 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 176 1.1E-44 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 Gene3D G3DSA:3.30.390.50 182 287 4.7E-27 T 12-10-2018 AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 SUPERFAMILY SSF56176 3 176 2.18E-50 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 Gene3D G3DSA:3.30.465.10 60 177 1.3E-36 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 SUPERFAMILY SSF55447 182 287 1.07E-24 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 Gene3D G3DSA:3.30.43.10 2 55 4.2E-22 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_27210 4c9de93d765bbff4cc19eb3494561fce 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 182 283 1.2E-21 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_35545 b1dd16c3f5685929bc778cc36cea083c 259 Gene3D G3DSA:3.20.20.190 4 256 9.4E-65 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_35545 b1dd16c3f5685929bc778cc36cea083c 259 SUPERFAMILY SSF51695 6 253 2.33E-64 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_35545 b1dd16c3f5685929bc778cc36cea083c 259 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 249 1.1E-39 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFR_10505 814191bc8bdd12b862c481c1563ede25 201 Gene3D G3DSA:3.90.226.10 19 199 6.7E-36 T 12-10-2018 AFR_10505 814191bc8bdd12b862c481c1563ede25 201 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 3.4E-10 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_10505 814191bc8bdd12b862c481c1563ede25 201 PRINTS PR00127 Clp protease catalytic subunit P signature 175 194 3.4E-10 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_10505 814191bc8bdd12b862c481c1563ede25 201 PRINTS PR00127 Clp protease catalytic subunit P signature 67 87 3.4E-10 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_10505 814191bc8bdd12b862c481c1563ede25 201 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 3.4E-10 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_10505 814191bc8bdd12b862c481c1563ede25 201 SUPERFAMILY SSF52096 26 198 2.05E-31 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_10505 814191bc8bdd12b862c481c1563ede25 201 Pfam PF00574 Clp protease 31 198 1.7E-28 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 SUPERFAMILY SSF81660 341 487 2.68E-25 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 SUPERFAMILY SSF56784 329 603 1.52E-36 T 12-10-2018 IPR036412 HAD-like superfamily AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 567 7.5E-31 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 SUPERFAMILY SSF81665 52 324 1.02E-10 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 SUPERFAMILY SSF81653 125 218 4.97E-21 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 Pfam PF00122 E1-E2 ATPase 119 308 3.6E-33 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 Gene3D G3DSA:2.70.150.20 116 223 7.4E-27 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 Gene3D G3DSA:3.40.50.1000 484 603 2.2E-24 T 12-10-2018 IPR023214 HAD superfamily AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 332 338 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 500 510 3.4E-25 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 588 3.4E-25 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 572 3.4E-25 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 3.4E-25 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 3.4E-25 T 12-10-2018 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 33 713 5.1E-300 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 Gene3D G3DSA:3.40.1110.10 341 483 1.4E-47 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 86 366 1.3E-26 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 424 635 2.2E-40 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFR_13815 d54cfdced73ee04da10a64c0c23e9115 719 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 29 717 40.323 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFR_04640 852647845294848acd97112742424a04 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.9E-32 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04640 852647845294848acd97112742424a04 126 Gene3D G3DSA:4.10.910.10 73 126 1.0E-24 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04640 852647845294848acd97112742424a04 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04640 852647845294848acd97112742424a04 126 PIRSF PIRSF002134 1 125 8.3E-43 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04640 852647845294848acd97112742424a04 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.2E-50 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04640 852647845294848acd97112742424a04 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.862 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04640 852647845294848acd97112742424a04 126 Gene3D G3DSA:1.10.8.50 1 72 1.0E-28 T 12-10-2018 AFR_04640 852647845294848acd97112742424a04 126 SUPERFAMILY SSF46946 2 122 7.46E-46 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 9 164 1.1E-46 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 Pfam PF04542 Sigma-70 region 2 19 83 3.4E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 Gene3D G3DSA:1.10.10.10 85 166 5.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 Gene3D G3DSA:1.10.1740.10 5 84 1.3E-8 T 12-10-2018 AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 163 2.1E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 SUPERFAMILY SSF88659 104 163 6.35E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 Pfam PF08281 Sigma-70, region 4 108 159 2.3E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_28265 c1a305c51b7ab543e429e5d74b16210e 172 SUPERFAMILY SSF88946 16 88 2.9E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 Gene3D G3DSA:1.20.140.10 295 468 6.2E-31 T 12-10-2018 AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 SUPERFAMILY SSF47203 295 483 3.38E-29 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 Gene3D G3DSA:1.10.540.10 35 154 2.2E-5 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 462 6.2E-13 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 31 2.2E-8 T 12-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 480 613 7.9E-26 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 Gene3D G3DSA:2.40.110.10 160 294 4.4E-24 T 12-10-2018 AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 275 2.5E-16 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_00430 862bd29e592df4da315ef85b74e3b2c3 618 SUPERFAMILY SSF56645 36 298 5.24E-40 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 Pfam PF00989 PAS fold 314 425 5.1E-12 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 312 435 3.1E-17 T 12-10-2018 IPR000014 PAS domain AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 Gene3D G3DSA:3.30.70.270 432 597 2.2E-53 T 12-10-2018 AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 SMART SM00267 428 594 6.5E-61 T 12-10-2018 IPR000160 GGDEF domain AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 Gene3D G3DSA:3.30.450.20 303 425 3.6E-20 T 12-10-2018 AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 Pfam PF00990 Diguanylate cyclase, GGDEF domain 439 588 5.3E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 SUPERFAMILY SSF55073 444 594 6.41E-44 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 SMART SM00091 314 380 7.4E-14 T 12-10-2018 IPR000014 PAS domain AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 435 593 4.2E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_34560 b78a051f40ce976fe834266baf82f8ca 609 SUPERFAMILY SSF55785 304 426 6.28E-21 T 12-10-2018 IPR035965 PAS domain superfamily AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 SMART SM00028 35 68 38.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 SMART SM00028 69 102 26.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 SMART SM00028 137 170 38.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 SMART SM00028 103 136 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 Gene3D G3DSA:1.25.40.10 8 189 7.7E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 Pfam PF13432 Tetratricopeptide repeat 8 69 0.0094 T 12-10-2018 AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 Pfam PF13432 Tetratricopeptide repeat 81 135 5.9E-8 T 12-10-2018 AFR_02935 d9bdf55f03f77caca699ec5484c250d2 245 SUPERFAMILY SSF48452 11 174 5.93E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_10355 fc62629400ef6532f7c976f751192a8a 591 Pfam PF13519 von Willebrand factor type A domain 394 511 1.1E-6 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_10355 fc62629400ef6532f7c976f751192a8a 591 SMART SM00327 391 589 8.9E-7 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_10355 fc62629400ef6532f7c976f751192a8a 591 Pfam PF13531 Bacterial extracellular solute-binding protein 36 337 8.0E-32 T 12-10-2018 AFR_10355 fc62629400ef6532f7c976f751192a8a 591 SUPERFAMILY SSF53850 33 337 1.48E-10 T 12-10-2018 AFR_10355 fc62629400ef6532f7c976f751192a8a 591 SUPERFAMILY SSF53300 392 583 4.96E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_10355 fc62629400ef6532f7c976f751192a8a 591 Gene3D G3DSA:3.40.50.410 393 589 1.2E-21 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 Pfam PF03462 PCRF domain 33 219 1.0E-56 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 Pfam PF00472 RF-1 domain 229 336 2.5E-38 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 5 363 1.7E-153 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 Gene3D G3DSA:3.30.70.1660 129 357 1.6E-89 T 12-10-2018 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 Gene3D G3DSA:3.30.160.20 225 319 1.6E-89 T 12-10-2018 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 Gene3D G3DSA:1.20.58.410 4 115 1.5E-24 T 12-10-2018 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 SMART SM00937 80 194 2.1E-46 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 SUPERFAMILY SSF75620 30 367 3.4E-124 T 12-10-2018 AFR_05840 4d410d5214be7ff8e11294fd1bfcc347 371 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 37.217 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 Gene3D G3DSA:3.30.9.10 110 366 6.2E-120 T 12-10-2018 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 SUPERFAMILY SSF51905 30 368 1.3E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 422 545 2.5E-31 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 60 72 1.3E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 359 365 1.3E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 106 118 1.3E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 44 54 1.3E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 389 401 1.3E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 31 43 1.3E-32 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 394 404 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 Gene3D G3DSA:1.10.8.870 433 572 8.7E-31 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 36 53 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 Gene3D G3DSA:3.50.50.60 32 408 6.2E-120 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_40860 6899d2df0be1bbe64e370b4a1c421198 599 Pfam PF01266 FAD dependent oxidoreductase 32 372 1.3E-51 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_17005 7568444bb230521a1b92a5f09e879d59 166 Pfam PF13302 Acetyltransferase (GNAT) domain 3 138 5.9E-11 T 12-10-2018 IPR000182 GNAT domain AFR_17005 7568444bb230521a1b92a5f09e879d59 166 Gene3D G3DSA:3.40.630.30 1 165 2.8E-18 T 12-10-2018 AFR_17005 7568444bb230521a1b92a5f09e879d59 166 SUPERFAMILY SSF55729 2 142 1.44E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 Pfam PF00743 Flavin-binding monooxygenase-like 13 397 7.3E-61 T 12-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 Gene3D G3DSA:3.50.50.60 9 374 1.0E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 311 338 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 358 375 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 109 121 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 198 213 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 12 28 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 60 78 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 171 185 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 84 99 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 125 141 1.5E-31 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 PIRSF PIRSF000332 10 445 3.3E-67 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 SUPERFAMILY SSF51905 14 233 1.37E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09565 a9b44c9408611c2c82cc518463f6e6ed 448 SUPERFAMILY SSF51905 185 388 2.27E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_03905 223c67620301ddbca191e8ee60e9f948 458 Pfam PF01979 Amidohydrolase family 145 436 4.6E-13 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_03905 223c67620301ddbca191e8ee60e9f948 458 SUPERFAMILY SSF51556 53 407 8.66E-38 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_03905 223c67620301ddbca191e8ee60e9f948 458 Gene3D G3DSA:2.30.40.10 20 54 1.2E-5 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_03905 223c67620301ddbca191e8ee60e9f948 458 SUPERFAMILY SSF51338 4 434 4.53E-13 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_32575 9e62928e2522a430187a37dc8314cb6e 354 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 7 354 8.7E-153 T 12-10-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AFR_32575 9e62928e2522a430187a37dc8314cb6e 354 SUPERFAMILY SSF53187 7 353 6.29E-41 T 12-10-2018 AFR_32575 9e62928e2522a430187a37dc8314cb6e 354 Pfam PF01546 Peptidase family M20/M25/M40 64 352 7.0E-20 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_32575 9e62928e2522a430187a37dc8314cb6e 354 Gene3D G3DSA:3.30.70.360 169 277 2.0E-96 T 12-10-2018 AFR_32575 9e62928e2522a430187a37dc8314cb6e 354 Pfam PF07687 Peptidase dimerisation domain 169 266 4.1E-18 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFR_32575 9e62928e2522a430187a37dc8314cb6e 354 SUPERFAMILY SSF55031 169 271 2.69E-22 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFR_32575 9e62928e2522a430187a37dc8314cb6e 354 Gene3D G3DSA:3.40.630.10 15 341 2.0E-96 T 12-10-2018 AFR_36735 7ab150efb2402cddb91b9578cdbc7ec2 301 SMART SM00382 26 221 7.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36735 7ab150efb2402cddb91b9578cdbc7ec2 301 SUPERFAMILY SSF52540 1 227 1.36E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36735 7ab150efb2402cddb91b9578cdbc7ec2 301 Gene3D G3DSA:3.40.50.300 1 238 5.4E-58 T 12-10-2018 AFR_36735 7ab150efb2402cddb91b9578cdbc7ec2 301 Pfam PF00005 ABC transporter 17 163 6.2E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_36735 7ab150efb2402cddb91b9578cdbc7ec2 301 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07300 5f80d199381ebe035f4976d62894d21c 356 Gene3D G3DSA:3.30.2010.10 67 154 4.8E-14 T 12-10-2018 AFR_07300 5f80d199381ebe035f4976d62894d21c 356 Pfam PF01435 Peptidase family M48 75 267 7.7E-25 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFR_17985 1c9e00295e9ebc76de5b3d0a06ec3a7e 445 Pfam PF01547 Bacterial extracellular solute-binding protein 53 351 2.0E-36 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_17985 1c9e00295e9ebc76de5b3d0a06ec3a7e 445 Gene3D G3DSA:3.40.190.10 159 434 1.3E-113 T 12-10-2018 AFR_17985 1c9e00295e9ebc76de5b3d0a06ec3a7e 445 Gene3D G3DSA:3.40.190.10 70 404 1.3E-113 T 12-10-2018 AFR_17985 1c9e00295e9ebc76de5b3d0a06ec3a7e 445 SUPERFAMILY SSF53850 25 443 5.66E-72 T 12-10-2018 AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 Gene3D G3DSA:3.50.50.60 16 168 2.3E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 SUPERFAMILY SSF54373 127 312 9.03E-32 T 12-10-2018 AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 Gene3D G3DSA:3.30.410.40 169 301 3.4E-12 T 12-10-2018 AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 Gene3D G3DSA:3.50.50.60 302 368 2.4E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 91 105 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 Pfam PF00732 GMC oxidoreductase 2 131 5.5E-28 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 Pfam PF05199 GMC oxidoreductase 227 357 7.9E-34 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AFR_13105 5d0f5d248bc43d11a6ea6924a07b8845 371 SUPERFAMILY SSF51905 5 366 1.25E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_34340 0e1d61efdded6550bb31ede26c92761a 456 SMART SM00606 33 167 4.9E-43 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_34340 0e1d61efdded6550bb31ede26c92761a 456 Gene3D G3DSA:2.60.120.260 34 166 1.1E-38 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_34340 0e1d61efdded6550bb31ede26c92761a 456 Pfam PF03422 Carbohydrate binding module (family 6) 41 166 4.4E-34 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_34340 0e1d61efdded6550bb31ede26c92761a 456 SUPERFAMILY SSF49785 35 166 1.17E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_34340 0e1d61efdded6550bb31ede26c92761a 456 Pfam PF09362 Domain of unknown function (DUF1996) 222 431 1.5E-48 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_04300 612bed7ebf8a25efb0d82f696aa5fcd0 455 Gene3D G3DSA:2.80.10.50 327 454 2.1E-34 T 12-10-2018 AFR_04300 612bed7ebf8a25efb0d82f696aa5fcd0 455 SUPERFAMILY SSF49899 37 269 7.55E-18 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_04300 612bed7ebf8a25efb0d82f696aa5fcd0 455 SMART SM00458 329 455 8.7E-23 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_04300 612bed7ebf8a25efb0d82f696aa5fcd0 455 Pfam PF00652 Ricin-type beta-trefoil lectin domain 331 452 2.9E-24 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_04300 612bed7ebf8a25efb0d82f696aa5fcd0 455 Gene3D G3DSA:2.60.120.200 47 272 3.7E-16 T 12-10-2018 AFR_04300 612bed7ebf8a25efb0d82f696aa5fcd0 455 SUPERFAMILY SSF50370 325 452 3.28E-33 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_25450 a0eedf3968b99b5690d4f41bfac91eee 384 Pfam PF01048 Phosphorylase superfamily 5 242 5.9E-34 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFR_25450 a0eedf3968b99b5690d4f41bfac91eee 384 Gene3D G3DSA:3.40.50.1580 5 255 7.1E-57 T 12-10-2018 AFR_25450 a0eedf3968b99b5690d4f41bfac91eee 384 SUPERFAMILY SSF53167 5 250 1.83E-42 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFR_15735 57607d6ab5e0e1c197ec1d8965327bbb 281 SUPERFAMILY SSF56281 22 252 1.28E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_15735 57607d6ab5e0e1c197ec1d8965327bbb 281 SMART SM00849 34 248 3.3E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_15735 57607d6ab5e0e1c197ec1d8965327bbb 281 Gene3D G3DSA:3.60.15.10 2 269 3.8E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_15735 57607d6ab5e0e1c197ec1d8965327bbb 281 Pfam PF00753 Metallo-beta-lactamase superfamily 39 223 1.1E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_07975 3263895c3e117b21d9260046814d04af 378 Pfam PF07650 KH domain 291 367 4.4E-13 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_07975 3263895c3e117b21d9260046814d04af 378 Gene3D G3DSA:3.40.50.300 88 268 3.8E-42 T 12-10-2018 AFR_07975 3263895c3e117b21d9260046814d04af 378 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 96 251 1.3E-20 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_07975 3263895c3e117b21d9260046814d04af 378 SUPERFAMILY SSF54814 264 378 1.31E-34 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFR_07975 3263895c3e117b21d9260046814d04af 378 Hamap MF_00367 GTPase Era [era]. 89 378 33.827 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07975 3263895c3e117b21d9260046814d04af 378 Pfam PF01926 50S ribosome-binding GTPase 94 208 6.4E-20 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_07975 3263895c3e117b21d9260046814d04af 378 SUPERFAMILY SSF52540 95 296 1.02E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07975 3263895c3e117b21d9260046814d04af 378 TIGRFAM TIGR00436 era: GTP-binding protein Era 92 361 2.3E-72 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07975 3263895c3e117b21d9260046814d04af 378 Gene3D G3DSA:3.30.300.20 269 378 1.0E-36 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_42495 d838b274c9bd7c7f6cb1d37b9dc95d10 559 Gene3D G3DSA:1.20.1730.10 35 523 8.6E-55 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily AFR_42495 d838b274c9bd7c7f6cb1d37b9dc95d10 559 Pfam PF00474 Sodium:solute symporter family 48 483 3.4E-92 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 Gene3D G3DSA:3.30.420.40 1 169 5.6E-67 T 12-10-2018 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 SUPERFAMILY SSF53067 133 363 6.83E-76 T 12-10-2018 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 SUPERFAMILY SSF53067 1 169 2.98E-58 T 12-10-2018 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 Hamap MF_00020 Acetate kinase [ackA]. 1 366 157.73 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 PIRSF PIRSF000722 1 366 5.5E-131 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 177 194 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 Pfam PF00871 Acetokinase family 2 360 1.4E-125 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 Gene3D G3DSA:3.30.420.40 171 366 5.0E-73 T 12-10-2018 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 TIGRFAM TIGR00016 ackA: acetate kinase 1 362 4.1E-121 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 PRINTS PR00471 Acetate kinase family signature 147 160 8.8E-41 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 PRINTS PR00471 Acetate kinase family signature 347 359 8.8E-41 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 PRINTS PR00471 Acetate kinase family signature 295 311 8.8E-41 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 PRINTS PR00471 Acetate kinase family signature 3 14 8.8E-41 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 PRINTS PR00471 Acetate kinase family signature 177 198 8.8E-41 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 PRINTS PR00471 Acetate kinase family signature 273 286 8.8E-41 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_38000 b09276938d2c63050a7f4b1ab7c09611 366 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFR_04165 c523a52e94be3861e50f845724b96227 103 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 9 86 3.4E-18 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFR_04165 c523a52e94be3861e50f845724b96227 103 SUPERFAMILY SSF46767 8 83 1.19E-14 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AFR_04165 c523a52e94be3861e50f845724b96227 103 Gene3D G3DSA:1.10.10.10 7 103 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29870 93937590fbd9dbfa0308d648b142e849 310 Gene3D G3DSA:3.40.50.300 48 309 3.8E-82 T 12-10-2018 AFR_29870 93937590fbd9dbfa0308d648b142e849 310 SUPERFAMILY SSF52540 54 304 1.18E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29870 93937590fbd9dbfa0308d648b142e849 310 Pfam PF13614 AAA domain 55 230 1.0E-61 T 12-10-2018 IPR025669 AAA domain AFR_23950 c06476b0b05b5361848ab1a895f87837 297 SUPERFAMILY SSF46785 5 87 4.57E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23950 c06476b0b05b5361848ab1a895f87837 297 Pfam PF03466 LysR substrate binding domain 93 281 1.6E-17 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_23950 c06476b0b05b5361848ab1a895f87837 297 Gene3D G3DSA:3.40.190.10 258 275 6.3E-6 T 12-10-2018 AFR_23950 c06476b0b05b5361848ab1a895f87837 297 Gene3D G3DSA:1.10.10.10 1 88 6.7E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23950 c06476b0b05b5361848ab1a895f87837 297 Gene3D G3DSA:3.40.190.290 94 194 1.4E-12 T 12-10-2018 AFR_23950 c06476b0b05b5361848ab1a895f87837 297 Gene3D G3DSA:3.40.190.10 218 257 6.3E-6 T 12-10-2018 AFR_23950 c06476b0b05b5361848ab1a895f87837 297 SUPERFAMILY SSF53850 93 284 1.52E-18 T 12-10-2018 AFR_23950 c06476b0b05b5361848ab1a895f87837 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23950 c06476b0b05b5361848ab1a895f87837 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23950 c06476b0b05b5361848ab1a895f87837 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23950 c06476b0b05b5361848ab1a895f87837 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.7E-24 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_21680 85cfda92c4cc544bab07a92bc8b949a5 284 Gene3D G3DSA:1.10.3720.10 6 276 3.7E-79 T 12-10-2018 IPR035906 MetI-like superfamily AFR_21680 85cfda92c4cc544bab07a92bc8b949a5 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 277 2.5E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_21680 85cfda92c4cc544bab07a92bc8b949a5 284 SUPERFAMILY SSF161098 15 284 1.96E-80 T 12-10-2018 IPR035906 MetI-like superfamily AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 Pfam PF03466 LysR substrate binding domain 88 289 1.4E-45 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 Gene3D G3DSA:1.10.10.10 1 83 1.2E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 SUPERFAMILY SSF53850 89 290 1.01E-42 T 12-10-2018 AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 SUPERFAMILY SSF46785 1 85 3.27E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.1E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_03810 203b709eb41c528bd6b84bc31b5bb432 519 Gene3D G3DSA:3.40.190.290 90 292 1.2E-49 T 12-10-2018 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.4E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 SUPERFAMILY SSF46689 2 68 6.67E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 SUPERFAMILY SSF48498 77 202 6.78E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 202 1.2E-10 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 PRINTS PR00400 Tetracycline repressor protein signature 186 200 8.8E-10 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 PRINTS PR00400 Tetracycline repressor protein signature 78 97 8.8E-10 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 PRINTS PR00400 Tetracycline repressor protein signature 26 49 8.8E-10 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 Gene3D G3DSA:1.10.357.10 1 209 1.9E-56 T 12-10-2018 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 6.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_38980 ce6e61ea4096886fd07d21ae95639e12 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 6.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 SUPERFAMILY SSF52540 8 133 2.98E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 SMART SM00387 715 824 4.2E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Pfam PF00512 His Kinase A (phospho-acceptor) domain 606 673 2.7E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Gene3D G3DSA:3.40.50.620 217 354 1.6E-6 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 2.1E-100 T 12-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Gene3D G3DSA:3.40.50.300 1 210 1.6E-100 T 12-10-2018 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 SUPERFAMILY SSF55874 663 822 4.98E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 SMART SM00388 605 673 1.3E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Pfam PF00582 Universal stress protein family 231 337 6.3E-7 T 12-10-2018 IPR006016 UspA AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Gene3D G3DSA:1.20.120.620 376 480 4.6E-16 T 12-10-2018 IPR038318 KdpD, transmembrane domain superfamily AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 SUPERFAMILY SSF47384 597 673 4.51E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Pfam PF13493 Domain of unknown function (DUF4118) 382 486 3.5E-27 T 12-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 PRINTS PR00344 Bacterial sensor protein C-terminal signature 752 766 6.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 PRINTS PR00344 Bacterial sensor protein C-terminal signature 785 803 6.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 PRINTS PR00344 Bacterial sensor protein C-terminal signature 809 822 6.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 716 823 8.3E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 SUPERFAMILY SSF52402 232 337 1.2E-8 T 12-10-2018 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Gene3D G3DSA:1.10.287.130 596 672 4.6E-16 T 12-10-2018 AFR_13825 3dcc89266f0de603078221e1b2242e8f 824 Gene3D G3DSA:3.30.565.10 678 824 3.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 SUPERFAMILY SSF56784 4 226 2.56E-32 T 12-10-2018 IPR036412 HAD-like superfamily AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 Pfam PF00702 haloacid dehalogenase-like hydrolase 5 187 2.0E-13 T 12-10-2018 AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 5.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 5.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 5.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 5.7E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 85 189 5.0E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_40030 5746daff917dbf8a6dd2852c1515289e 232 Gene3D G3DSA:3.40.50.1000 3 200 4.4E-31 T 12-10-2018 IPR023214 HAD superfamily AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Gene3D G3DSA:2.130.10.10 833 1043 1.3E-62 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Gene3D G3DSA:2.130.10.10 663 832 2.1E-53 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 896 910 - T 12-10-2018 IPR019775 WD40 repeat, conserved site AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 728 742 - T 12-10-2018 IPR019775 WD40 repeat, conserved site AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Gene3D G3DSA:2.130.10.10 1044 1122 1.9E-22 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF13191 AAA ATPase domain 52 193 1.5E-10 T 12-10-2018 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SUPERFAMILY SSF50978 873 1119 3.3E-75 T 12-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SUPERFAMILY SSF52540 51 290 1.77E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 686 700 - T 12-10-2018 IPR019775 WD40 repeat, conserved site AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SUPERFAMILY SSF50978 535 863 7.02E-88 T 12-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 870 909 1.2E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 702 741 1.1E-8 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 1080 1119 7.2E-6 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 996 1035 2.8E-7 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 534 573 9.1E-7 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 1038 1077 1.5E-8 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 619 658 1.2E-8 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 954 993 1.3E-10 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 831 867 210.0 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 577 616 1.9E-9 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 912 951 8.4E-10 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 660 699 1.5E-9 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 744 783 2.1E-10 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 SMART SM00320 786 825 9.4E-7 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Gene3D G3DSA:3.40.50.300 41 240 6.4E-9 T 12-10-2018 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 703 741 2.5E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 876 909 3.1E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 913 951 5.5E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 793 824 2.1E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 1001 1035 0.0015 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 662 699 3.1E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 1043 1076 1.2E-4 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 624 658 2.0E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 745 783 6.4E-6 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 538 572 0.0047 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 1081 1118 0.013 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 580 616 7.5E-6 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Pfam PF00400 WD domain, G-beta repeat 956 993 5.6E-6 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 Gene3D G3DSA:2.130.10.10 526 662 3.2E-39 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 645 659 - T 12-10-2018 IPR019775 WD40 repeat, conserved site AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 PRINTS PR00320 G protein beta WD-40 repeat signature 686 700 1.0E-6 T 12-10-2018 IPR020472 G-protein beta WD-40 repeat AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 PRINTS PR00320 G protein beta WD-40 repeat signature 770 784 1.0E-6 T 12-10-2018 IPR020472 G-protein beta WD-40 repeat AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 PRINTS PR00320 G protein beta WD-40 repeat signature 896 910 1.0E-6 T 12-10-2018 IPR020472 G-protein beta WD-40 repeat AFR_08285 597ab41bc23ef0e1d082f623222c9173 1151 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 770 784 - T 12-10-2018 IPR019775 WD40 repeat, conserved site AFR_18370 d84deffb02efbddbdd13885f403b5fef 500 SUPERFAMILY SSF53383 145 441 1.7E-7 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SUPERFAMILY SSF50249 650 724 1.48E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SUPERFAMILY SSF55666 155 263 3.93E-25 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SMART SM00322 582 647 2.8E-13 T 12-10-2018 IPR004087 K Homology domain GO:0003676 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SUPERFAMILY SSF55666 477 575 1.51E-23 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 21 721 1.6E-262 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 13 726 27.083 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 270 346 1.3E-15 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Pfam PF00575 S1 RNA binding domain 651 718 2.7E-10 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 PIRSF PIRSF005499 11 748 2.8E-280 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Pfam PF01138 3' exoribonuclease family, domain 1 24 154 2.9E-19 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Pfam PF01138 3' exoribonuclease family, domain 1 351 483 7.1E-17 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SMART SM00316 652 723 9.3E-15 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SUPERFAMILY SSF54211 321 518 1.32E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SUPERFAMILY SSF54791 578 685 1.61E-17 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Gene3D G3DSA:2.40.50.140 581 705 3.4E-44 T 12-10-2018 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Gene3D G3DSA:3.30.230.70 8 253 1.3E-84 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SUPERFAMILY SSF54211 14 154 6.58E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Pfam PF00013 KH domain 586 643 2.0E-11 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 SUPERFAMILY SSF46915 267 347 2.46E-17 T 12-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 Gene3D G3DSA:3.30.230.70 263 580 9.8E-107 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_35910 98a4c3dee3c36aef81c62bf5fb84b9c3 777 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 11 720 0.0 T 12-10-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 Gene3D G3DSA:3.30.565.10 432 588 1.3E-47 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 Gene3D G3DSA:1.10.287.130 307 419 2.9E-22 T 12-10-2018 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 SUPERFAMILY SSF158472 310 359 9.15E-8 T 12-10-2018 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 SMART SM00387 472 584 9.1E-44 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 SMART SM00304 310 362 1.9E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 SUPERFAMILY SSF55874 416 583 1.2E-49 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 SMART SM00388 363 427 1.4E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 6.1E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 6.1E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 581 6.1E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 6.1E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 Pfam PF00672 HAMP domain 310 359 3.6E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 SUPERFAMILY SSF47384 347 428 1.96E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 582 3.2E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_21160 beda43b6a31d5df46a34754cb3be674c 593 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 427 2.6E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13740 196afcef6acf1710ab6ef9931bb26d88 397 SUPERFAMILY SSF55874 295 394 1.47E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13740 196afcef6acf1710ab6ef9931bb26d88 397 Pfam PF07730 Histidine kinase 189 255 1.3E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_13740 196afcef6acf1710ab6ef9931bb26d88 397 Gene3D G3DSA:3.30.565.10 265 395 8.5E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07635 aba323a14669700db2f47f94dd31d319 489 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 5 191 4.0E-35 T 12-10-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein AFR_07635 aba323a14669700db2f47f94dd31d319 489 Gene3D G3DSA:1.10.10.1710 427 487 5.8E-17 T 12-10-2018 AFR_07635 aba323a14669700db2f47f94dd31d319 489 Gene3D G3DSA:1.10.579.10 303 426 1.2E-48 T 12-10-2018 AFR_07635 aba323a14669700db2f47f94dd31d319 489 SUPERFAMILY SSF48173 208 465 1.16E-46 T 12-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 AFR_07635 aba323a14669700db2f47f94dd31d319 489 Gene3D G3DSA:3.40.50.620 6 210 4.8E-80 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_07635 aba323a14669700db2f47f94dd31d319 489 Gene3D G3DSA:1.25.40.80 106 299 4.8E-80 T 12-10-2018 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 SMART SM00633 84 357 8.8E-93 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 Gene3D G3DSA:3.20.20.80 31 359 1.0E-107 T 12-10-2018 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 Pfam PF00331 Glycosyl hydrolase family 10 63 354 8.8E-93 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 PRINTS PR00134 Glycosyl hydrolase family 10 signature 159 170 1.6E-11 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 PRINTS PR00134 Glycosyl hydrolase family 10 signature 115 127 1.6E-11 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 PRINTS PR00134 Glycosyl hydrolase family 10 signature 204 215 1.6E-11 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 PRINTS PR00134 Glycosyl hydrolase family 10 signature 233 245 1.6E-11 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_03795 33ec44f2255dbae34bbee86d02a5d7b7 364 SUPERFAMILY SSF51445 32 357 5.37E-103 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_03355 daf3b62b68ab83649595bcb761bf6033 393 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 160 1.0E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_03355 daf3b62b68ab83649595bcb761bf6033 393 SUPERFAMILY SSF88659 100 159 8.94E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_03355 daf3b62b68ab83649595bcb761bf6033 393 Pfam PF04542 Sigma-70 region 2 16 76 2.2E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_03355 daf3b62b68ab83649595bcb761bf6033 393 Gene3D G3DSA:1.10.1740.10 2 80 1.2E-8 T 12-10-2018 AFR_03355 daf3b62b68ab83649595bcb761bf6033 393 Pfam PF08281 Sigma-70, region 4 107 158 1.1E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_03355 daf3b62b68ab83649595bcb761bf6033 393 SUPERFAMILY SSF88946 15 91 4.32E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 PRINTS PR00149 Fumarate lyase superfamily signature 203 221 3.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family AFR_29285 5a85b585119d0a65166df64e972abfd5 501 PRINTS PR00149 Fumarate lyase superfamily signature 340 356 3.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family AFR_29285 5a85b585119d0a65166df64e972abfd5 501 PRINTS PR00149 Fumarate lyase superfamily signature 294 321 3.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family AFR_29285 5a85b585119d0a65166df64e972abfd5 501 PRINTS PR00149 Fumarate lyase superfamily signature 157 175 3.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family AFR_29285 5a85b585119d0a65166df64e972abfd5 501 Pfam PF00206 Lyase 35 365 7.3E-96 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_29285 5a85b585119d0a65166df64e972abfd5 501 SUPERFAMILY SSF48557 27 483 1.73E-134 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 Gene3D G3DSA:1.20.200.10 162 430 6.0E-97 T 12-10-2018 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 PRINTS PR00145 Argininosuccinate lyase family signature 198 218 4.4E-7 T 12-10-2018 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 PRINTS PR00145 Argininosuccinate lyase family signature 156 178 4.4E-7 T 12-10-2018 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 PRINTS PR00145 Argininosuccinate lyase family signature 340 356 4.4E-7 T 12-10-2018 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 Gene3D G3DSA:1.10.275.10 28 161 1.6E-55 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_29285 5a85b585119d0a65166df64e972abfd5 501 Gene3D G3DSA:1.10.40.30 431 484 7.6E-24 T 12-10-2018 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 Pfam PF10415 Fumarase C C-terminus 431 483 7.6E-19 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 Hamap MF_00743 Fumarate hydratase class II [fumC]. 27 484 78.682 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_29285 5a85b585119d0a65166df64e972abfd5 501 ProSitePatterns PS00163 Fumarate lyases signature. 340 349 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFR_12390 d31063c8262c685e60f9072bcccdea9e 255 Pfam PF13490 Putative zinc-finger 15 43 2.7E-6 T 12-10-2018 IPR027383 Putative zinc-finger AFR_12390 d31063c8262c685e60f9072bcccdea9e 255 Gene3D G3DSA:1.10.10.1320 9 141 4.3E-5 T 12-10-2018 AFR_35960 abd5e2fb274a2cfc29b3a464cb85f868 155 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 5 108 7.1E-23 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFR_35960 abd5e2fb274a2cfc29b3a464cb85f868 155 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 95 4.0E-18 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFR_35960 abd5e2fb274a2cfc29b3a464cb85f868 155 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 AFR_35960 abd5e2fb274a2cfc29b3a464cb85f868 155 Gene3D G3DSA:3.30.300.20 1 102 1.5E-27 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_35960 abd5e2fb274a2cfc29b3a464cb85f868 155 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 5 108 24.339 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFR_35960 abd5e2fb274a2cfc29b3a464cb85f868 155 Pfam PF02033 Ribosome-binding factor A 7 108 3.8E-25 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFR_35960 abd5e2fb274a2cfc29b3a464cb85f868 155 SUPERFAMILY SSF89919 2 110 2.35E-28 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Gene3D G3DSA:2.40.50.100 49 220 2.6E-15 T 12-10-2018 AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Pfam PF13437 HlyD family secretion protein 259 357 4.0E-9 T 12-10-2018 AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Gene3D G3DSA:2.40.30.170 278 340 2.9E-8 T 12-10-2018 AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Pfam PF13533 Biotin-lipoyl like 52 93 1.0E-6 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Gene3D G3DSA:2.40.420.20 358 439 7.5E-19 T 12-10-2018 AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Gene3D G3DSA:2.40.30.170 38 48 2.6E-15 T 12-10-2018 AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Gene3D G3DSA:1.10.287.470 83 210 2.6E-15 T 12-10-2018 AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 Gene3D G3DSA:2.40.50.100 256 277 2.9E-8 T 12-10-2018 AFR_25615 5dd76710ff141492cb07025a5ecd5a7f 439 SUPERFAMILY SSF51230 46 88 2.86E-5 T 12-10-2018 IPR011053 Single hybrid motif AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 Gene3D G3DSA:3.30.930.10 104 420 1.7E-113 T 12-10-2018 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 PIRSF PIRSF001529 1 419 1.2E-133 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 Gene3D G3DSA:1.10.287.40 1 103 1.0E-18 T 12-10-2018 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 6.4E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 6.4E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 PRINTS PR00981 Seryl-tRNA synthetase signature 346 362 6.4E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 PRINTS PR00981 Seryl-tRNA synthetase signature 311 324 6.4E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 PRINTS PR00981 Seryl-tRNA synthetase signature 328 344 6.4E-31 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 218 393 1.2E-26 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 410 1.7E-124 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 SUPERFAMILY SSF46589 2 111 2.82E-22 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 5.9E-22 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 SUPERFAMILY SSF55681 116 411 4.15E-84 T 12-10-2018 AFR_42590 a1d316b54230df7a0cc0c8db824e3da7 420 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 37.727 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFR_09455 a20df8c93d2f8db96f49fbb81170fdac 276 SUPERFAMILY SSF53448 6 266 1.51E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_09455 a20df8c93d2f8db96f49fbb81170fdac 276 Pfam PF12804 MobA-like NTP transferase domain 7 116 6.6E-10 T 12-10-2018 IPR025877 MobA-like NTP transferase AFR_09455 a20df8c93d2f8db96f49fbb81170fdac 276 Gene3D G3DSA:3.90.550.10 6 217 6.7E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 Gene3D G3DSA:3.30.428.10 73 199 1.1E-90 T 12-10-2018 IPR036265 HIT-like superfamily AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 43 362 1.4E-43 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 SUPERFAMILY SSF54197 203 362 1.13E-32 T 12-10-2018 IPR036265 HIT-like superfamily AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 43 200 1.7E-36 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 215 360 6.9E-16 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 SUPERFAMILY SSF54197 41 201 3.57E-49 T 12-10-2018 IPR036265 HIT-like superfamily AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 175 192 - T 12-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 Gene3D G3DSA:3.30.428.10 44 360 1.1E-90 T 12-10-2018 IPR036265 HIT-like superfamily AFR_05145 071072fe5483376dd920f0bb8b7bba58 363 PIRSF PIRSF000808 35 363 3.4E-107 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_13270 2a70bb1cb599805295175ad193ecfa46 182 SUPERFAMILY SSF88946 6 92 4.71E-16 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_13270 2a70bb1cb599805295175ad193ecfa46 182 Pfam PF08281 Sigma-70, region 4 107 158 2.6E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_13270 2a70bb1cb599805295175ad193ecfa46 182 SUPERFAMILY SSF88659 102 162 4.49E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_13270 2a70bb1cb599805295175ad193ecfa46 182 Gene3D G3DSA:1.10.10.10 81 165 2.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13270 2a70bb1cb599805295175ad193ecfa46 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 162 3.7E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_13270 2a70bb1cb599805295175ad193ecfa46 182 Gene3D G3DSA:1.10.1740.10 1 75 3.0E-12 T 12-10-2018 AFR_13270 2a70bb1cb599805295175ad193ecfa46 182 Pfam PF04542 Sigma-70 region 2 13 79 2.6E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_18475 766fdc279e685667cf9db26378351d51 357 SUPERFAMILY SSF53686 35 304 3.27E-50 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_18475 766fdc279e685667cf9db26378351d51 357 Gene3D G3DSA:3.40.50.1100 141 291 8.6E-57 T 12-10-2018 AFR_18475 766fdc279e685667cf9db26378351d51 357 Gene3D G3DSA:3.40.50.1100 35 140 8.6E-57 T 12-10-2018 AFR_18475 766fdc279e685667cf9db26378351d51 357 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 273 7.8E-31 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_02185 ccfb0a3089fc5df1c7beaa722ea41568 146 Pfam PF00583 Acetyltransferase (GNAT) family 46 129 4.0E-14 T 12-10-2018 IPR000182 GNAT domain AFR_02185 ccfb0a3089fc5df1c7beaa722ea41568 146 SUPERFAMILY SSF55729 1 137 1.92E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_02185 ccfb0a3089fc5df1c7beaa722ea41568 146 Gene3D G3DSA:3.40.630.30 1 145 1.9E-25 T 12-10-2018 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 Gene3D G3DSA:2.60.40.290 525 631 1.9E-36 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 SUPERFAMILY SSF51445 200 519 3.52E-99 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_17645 d1527a9195ea6531ade2048da3740c36 631 Pfam PF00553 Cellulose binding domain 529 629 3.0E-31 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 Gene3D G3DSA:3.20.20.80 188 524 4.7E-121 T 12-10-2018 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 Gene3D G3DSA:2.60.120.260 30 183 2.2E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_17645 d1527a9195ea6531ade2048da3740c36 631 SMART SM00633 233 520 1.4E-135 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 SUPERFAMILY SSF49384 524 629 6.98E-33 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 SUPERFAMILY SSF49785 37 180 7.14E-34 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_17645 d1527a9195ea6531ade2048da3740c36 631 SMART SM00637 529 629 3.8E-45 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 Pfam PF00331 Glycosyl hydrolase family 10 199 518 7.5E-106 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 Pfam PF02018 Carbohydrate binding domain 38 167 1.4E-24 T 12-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 PRINTS PR00134 Glycosyl hydrolase family 10 signature 264 276 5.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 PRINTS PR00134 Glycosyl hydrolase family 10 signature 363 374 5.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 PRINTS PR00134 Glycosyl hydrolase family 10 signature 317 328 5.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17645 d1527a9195ea6531ade2048da3740c36 631 PRINTS PR00134 Glycosyl hydrolase family 10 signature 391 403 5.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_29390 0e8d201c70213b40231001f967593d64 269 Pfam PF04909 Amidohydrolase 4 235 4.7E-19 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_29390 0e8d201c70213b40231001f967593d64 269 Gene3D G3DSA:3.20.20.140 1 267 1.6E-42 T 12-10-2018 AFR_29390 0e8d201c70213b40231001f967593d64 269 SUPERFAMILY SSF51556 2 262 1.6E-33 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 427 489 8.9E-7 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 Gene3D G3DSA:1.10.1740.10 3 74 9.1E-7 T 12-10-2018 AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 SUPERFAMILY SSF88659 98 158 9.35E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 33 64 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 Pfam PF04542 Sigma-70 region 2 23 77 7.4E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 158 8.9E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 Gene3D G3DSA:1.10.150.130 416 498 2.9E-5 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 SUPERFAMILY SSF88946 12 96 2.59E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 SUPERFAMILY SSF56349 413 592 8.12E-11 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 Gene3D G3DSA:1.10.10.10 109 161 2.6E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_09205 338b53ec9cbdb25cfe6a45943b05faf6 656 Pfam PF08281 Sigma-70, region 4 105 156 1.7E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_13850 8003e484024cb80c0f8e341d6867a987 232 SUPERFAMILY SSF51735 4 230 3.7E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13850 8003e484024cb80c0f8e341d6867a987 232 Gene3D G3DSA:3.40.50.720 2 232 9.0E-62 T 12-10-2018 AFR_13850 8003e484024cb80c0f8e341d6867a987 232 Pfam PF00106 short chain dehydrogenase 4 196 2.3E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 6.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 6.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 6.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 6.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13850 8003e484024cb80c0f8e341d6867a987 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17540 7978c65fa7b074ec69f75e75fde8ddf0 179 SMART SM00458 39 172 1.2E-8 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17540 7978c65fa7b074ec69f75e75fde8ddf0 179 SUPERFAMILY SSF50370 41 169 1.1E-26 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_17540 7978c65fa7b074ec69f75e75fde8ddf0 179 Pfam PF00652 Ricin-type beta-trefoil lectin domain 43 169 9.0E-17 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17540 7978c65fa7b074ec69f75e75fde8ddf0 179 Gene3D G3DSA:2.80.10.50 40 171 3.6E-28 T 12-10-2018 AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 33 366 1.4E-133 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 Gene3D G3DSA:3.90.650.10 199 377 1.6E-60 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 33 374 41.733 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 Gene3D G3DSA:3.30.1330.10 32 197 1.1E-61 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 SUPERFAMILY SSF56042 200 372 1.5E-53 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 Pfam PF00586 AIR synthase related protein, N-terminal domain 88 191 9.9E-17 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 SUPERFAMILY SSF55326 32 196 2.44E-47 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_00745 e348cfde992358dac6e5cc4beb125f41 380 Pfam PF02769 AIR synthase related protein, C-terminal domain 204 369 2.2E-31 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFR_11725 383c311f542bfc9a86cdf55ed688f914 336 Pfam PF13480 Acetyltransferase (GNAT) domain 157 288 2.1E-22 T 12-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AFR_11725 383c311f542bfc9a86cdf55ed688f914 336 SUPERFAMILY SSF55729 145 301 6.67E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_11725 383c311f542bfc9a86cdf55ed688f914 336 Gene3D G3DSA:3.40.630.30 138 297 1.0E-25 T 12-10-2018 AFR_29455 7a9fbb62b5772367b8dac68cfa0c171a 470 SUPERFAMILY SSF56176 11 216 1.17E-44 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_29455 7a9fbb62b5772367b8dac68cfa0c171a 470 Pfam PF08031 Berberine and berberine like 432 467 1.3E-6 T 12-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 AFR_29455 7a9fbb62b5772367b8dac68cfa0c171a 470 Gene3D G3DSA:3.30.465.10 106 455 1.2E-94 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_29455 7a9fbb62b5772367b8dac68cfa0c171a 470 Gene3D G3DSA:3.40.462.20 217 427 1.2E-94 T 12-10-2018 AFR_29455 7a9fbb62b5772367b8dac68cfa0c171a 470 Pfam PF01565 FAD binding domain 51 183 2.1E-25 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_29455 7a9fbb62b5772367b8dac68cfa0c171a 470 Gene3D G3DSA:3.30.43.10 26 102 2.1E-14 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_33015 6e42ca53313f3993608063e3e79dd18d 383 Pfam PF13439 Glycosyltransferase Family 4 77 170 5.6E-8 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_33015 6e42ca53313f3993608063e3e79dd18d 383 Pfam PF13692 Glycosyl transferases group 1 186 337 5.5E-17 T 12-10-2018 AFR_33015 6e42ca53313f3993608063e3e79dd18d 383 SUPERFAMILY SSF53756 9 365 5.23E-41 T 12-10-2018 AFR_33015 6e42ca53313f3993608063e3e79dd18d 383 Gene3D G3DSA:3.40.50.2000 104 364 1.4E-35 T 12-10-2018 AFR_33015 6e42ca53313f3993608063e3e79dd18d 383 Gene3D G3DSA:3.40.50.2000 171 351 1.4E-35 T 12-10-2018 AFR_20080 26d97725a5d74fbf4b91585ddf04e670 318 SUPERFAMILY SSF51679 1 313 2.75E-64 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_20080 26d97725a5d74fbf4b91585ddf04e670 318 Pfam PF00296 Luciferase-like monooxygenase 3 292 7.5E-50 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_20080 26d97725a5d74fbf4b91585ddf04e670 318 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 5 318 7.5E-140 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related AFR_20080 26d97725a5d74fbf4b91585ddf04e670 318 Gene3D G3DSA:3.20.20.30 2 318 4.5E-66 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_14755 1d9142897079958dba1871ccda3d55c9 159 SUPERFAMILY SSF55961 7 151 1.26E-38 T 12-10-2018 AFR_14755 1d9142897079958dba1871ccda3d55c9 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 149 7.2E-23 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_14755 1d9142897079958dba1871ccda3d55c9 159 Gene3D G3DSA:3.30.530.20 1 152 4.6E-41 T 12-10-2018 IPR023393 START-like domain superfamily AFR_30385 22d27758a9afc55b9ebfef643d87f2c6 131 SUPERFAMILY SSF46785 7 81 7.49E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30385 22d27758a9afc55b9ebfef643d87f2c6 131 SMART SM00345 18 77 3.2E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_30385 22d27758a9afc55b9ebfef643d87f2c6 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 6.1E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_30385 22d27758a9afc55b9ebfef643d87f2c6 131 Gene3D G3DSA:1.10.10.10 11 131 2.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16205 a7e47526f2c506b34ad36286f598bded 336 Pfam PF00248 Aldo/keto reductase family 16 316 1.6E-66 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_16205 a7e47526f2c506b34ad36286f598bded 336 SUPERFAMILY SSF51430 1 317 2.36E-85 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_16205 a7e47526f2c506b34ad36286f598bded 336 Gene3D G3DSA:3.20.20.100 3 332 1.1E-107 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_37325 e0f3745f56ee799821b49285f9c8a466 93 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 85 9.2E-26 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37325 e0f3745f56ee799821b49285f9c8a466 93 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 92 11.774 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37325 e0f3745f56ee799821b49285f9c8a466 93 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 85 1.0E-18 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37325 e0f3745f56ee799821b49285f9c8a466 93 Gene3D G3DSA:2.60.15.10 2 89 1.1E-24 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37325 e0f3745f56ee799821b49285f9c8a466 93 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 88 1.7E-21 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37325 e0f3745f56ee799821b49285f9c8a466 93 SUPERFAMILY SSF51344 4 86 6.41E-21 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 Pfam PF00672 HAMP domain 228 276 1.7E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 470 645 3.1E-49 T 12-10-2018 IPR000160 GGDEF domain AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 Pfam PF00990 Diguanylate cyclase, GGDEF domain 474 640 1.6E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 SUPERFAMILY SSF55073 478 645 2.28E-46 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 SUPERFAMILY SSF55781 296 473 2.4E-21 T 12-10-2018 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 Pfam PF01590 GAF domain 305 460 3.4E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 SMART SM00267 462 645 2.6E-50 T 12-10-2018 IPR000160 GGDEF domain AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 Gene3D G3DSA:1.20.1480.50 202 282 8.1E-15 T 12-10-2018 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 SMART SM00304 228 280 6.4E-16 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 SMART SM00065 305 470 5.7E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 Gene3D G3DSA:3.30.70.270 470 648 2.8E-56 T 12-10-2018 AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 Gene3D G3DSA:3.30.450.40 283 469 3.6E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_39905 fc97c8441064524821bc25f2d7cdaef8 691 SUPERFAMILY SSF158472 228 279 7.72E-12 T 12-10-2018 AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 SUPERFAMILY SSF52540 10 251 7.34E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 Gene3D G3DSA:2.40.50.140 295 352 7.2E-10 T 12-10-2018 AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 SUPERFAMILY SSF50331 248 361 2.38E-7 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 Pfam PF00005 ABC transporter 30 171 1.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 Gene3D G3DSA:2.40.50.940 232 359 7.2E-10 T 12-10-2018 AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 Pfam PF08402 TOBE domain 288 360 6.1E-11 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 Gene3D G3DSA:3.40.50.300 10 231 4.4E-64 T 12-10-2018 AFR_24385 e6e8d79f7af8b7487f9b782d5c23adbe 363 SMART SM00382 38 221 1.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 Gene3D G3DSA:3.30.565.10 301 445 3.8E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 SMART SM00387 337 447 5.8E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 SMART SM00304 179 232 1.6E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 293 5.5E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 SMART SM00388 233 294 2.2E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 440 1.3E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 SUPERFAMILY SSF55874 283 445 2.49E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 SUPERFAMILY SSF158472 181 229 7.45E-5 T 12-10-2018 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 Gene3D G3DSA:1.10.287.130 183 295 9.1E-23 T 12-10-2018 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 2.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 2.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 401 2.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13155 33c8d0d35ef51929a2477d1a3430018a 449 SUPERFAMILY SSF47384 216 293 3.53E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 234 2.6E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 Gene3D G3DSA:1.10.10.10 88 141 1.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 PRINTS PR00046 Major sigma-70 factor signature 219 230 8.5E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 PRINTS PR00046 Major sigma-70 factor signature 187 199 8.5E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 PRINTS PR00046 Major sigma-70 factor signature 204 219 8.5E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 PRINTS PR00046 Major sigma-70 factor signature 42 55 8.5E-11 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 Gene3D G3DSA:1.10.10.10 166 235 2.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 SUPERFAMILY SSF88659 91 165 3.27E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 Gene3D G3DSA:1.20.120.1810 7 86 4.4E-17 T 12-10-2018 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 Pfam PF04542 Sigma-70 region 2 19 87 1.5E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 Pfam PF04539 Sigma-70 region 3 98 167 4.9E-15 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 SUPERFAMILY SSF88659 150 234 2.8E-19 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 Pfam PF04545 Sigma-70, region 4 183 231 1.4E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 13 234 5.5E-85 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_17515 6fba4d6ca295c2ca05fb9fd610587281 236 SUPERFAMILY SSF88946 11 87 2.75E-26 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24800 ef395706544c5776d4075539b5379f61 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 1.7E-28 T 12-10-2018 AFR_24800 ef395706544c5776d4075539b5379f61 252 Gene3D G3DSA:3.40.50.720 1 251 4.8E-40 T 12-10-2018 AFR_24800 ef395706544c5776d4075539b5379f61 252 SUPERFAMILY SSF51735 4 246 2.04E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24800 ef395706544c5776d4075539b5379f61 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.7E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24800 ef395706544c5776d4075539b5379f61 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.7E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24800 ef395706544c5776d4075539b5379f61 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.7E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24800 ef395706544c5776d4075539b5379f61 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.7E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24800 ef395706544c5776d4075539b5379f61 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.7E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24800 ef395706544c5776d4075539b5379f61 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 2.7E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 778 1112 4.7E-114 T 12-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 673 771 3.1E-29 T 12-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Gene3D G3DSA:2.60.40.10 207 313 2.1E-34 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 504 635 8.5E-44 T 12-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 1114 1184 4.8E-20 T 12-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain AFR_33310 1ce0818d625677446448179fea27c8e3 1214 PIRSF PIRSF010631 39 143 0.11 T 12-10-2018 IPR016007 Alpha-L-rhamnosidase AFR_33310 1ce0818d625677446448179fea27c8e3 1214 PIRSF PIRSF010631 197 429 8.7E-40 T 12-10-2018 IPR016007 Alpha-L-rhamnosidase AFR_33310 1ce0818d625677446448179fea27c8e3 1214 PIRSF PIRSF010631 442 1214 3.5E-232 T 12-10-2018 IPR016007 Alpha-L-rhamnosidase AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Gene3D G3DSA:2.60.120.260 47 198 3.1E-33 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Gene3D G3DSA:2.60.120.260 332 489 0.0 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33310 1ce0818d625677446448179fea27c8e3 1214 Gene3D G3DSA:1.50.10.10 320 1211 0.0 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_33310 1ce0818d625677446448179fea27c8e3 1214 SUPERFAMILY SSF48208 771 1178 4.22E-45 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_33310 1ce0818d625677446448179fea27c8e3 1214 SUPERFAMILY SSF49785 57 145 8.5E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33310 1ce0818d625677446448179fea27c8e3 1214 SUPERFAMILY SSF49785 326 426 8.36E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_13365 1703c394e0b0f677307e3855aed30f23 272 Gene3D G3DSA:3.40.50.720 2 272 1.4E-65 T 12-10-2018 AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 Pfam PF00106 short chain dehydrogenase 5 183 1.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 SUPERFAMILY SSF51735 3 246 8.38E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13365 1703c394e0b0f677307e3855aed30f23 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12930 df11ab19bf6ba9534051f8c93c9243d0 203 SMART SM00830 33 118 9.0E-15 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_12930 df11ab19bf6ba9534051f8c93c9243d0 203 Pfam PF01817 Chorismate mutase type II 47 115 1.7E-8 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_12930 df11ab19bf6ba9534051f8c93c9243d0 203 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 43 154 1.9E-27 T 12-10-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_12930 df11ab19bf6ba9534051f8c93c9243d0 203 SUPERFAMILY SSF48600 46 201 1.53E-27 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_12930 df11ab19bf6ba9534051f8c93c9243d0 203 Gene3D G3DSA:1.20.1250.110 32 203 1.4E-49 T 12-10-2018 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 SUPERFAMILY SSF68912 33 70 1.57E-5 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 SMART SM00357 360 422 3.8E-6 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 Hamap MF_01884 Transcription termination factor Rho [rho]. 352 729 193.582 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 Gene3D G3DSA:2.40.50.140 305 442 8.7E-30 T 12-10-2018 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 Gene3D G3DSA:3.40.50.300 444 727 7.5E-119 T 12-10-2018 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 SMART SM00959 33 73 8.2E-11 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 Pfam PF07497 Rho termination factor, RNA-binding domain 359 438 1.3E-28 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 TIGRFAM TIGR00767 rho: transcription termination factor Rho 34 727 6.6E-192 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 469 673 4.2E-21 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 SUPERFAMILY SSF50249 359 438 3.26E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 Pfam PF07498 Rho termination factor, N-terminal domain 34 70 2.2E-10 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 SMART SM00382 480 665 5.9E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 SUPERFAMILY SSF52540 399 680 1.02E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37450 20a204bfcb44622bd4b19b2f8ac8de59 733 Gene3D G3DSA:1.10.720.10 32 72 6.6E-6 T 12-10-2018 AFR_16735 8dda3b6a1d21ab2bbef508cf1b5abe97 481 Pfam PF01471 Putative peptidoglycan binding domain 164 199 5.1E-6 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_16735 8dda3b6a1d21ab2bbef508cf1b5abe97 481 SUPERFAMILY SSF47090 150 208 1.73E-9 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_16735 8dda3b6a1d21ab2bbef508cf1b5abe97 481 Gene3D G3DSA:1.10.101.10 150 221 3.5E-8 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_16735 8dda3b6a1d21ab2bbef508cf1b5abe97 481 Gene3D G3DSA:2.40.420.20 401 479 1.7E-7 T 12-10-2018 AFR_00510 2ab13cb328e27f607a9ce6f6be0693d9 559 SUPERFAMILY SSF52540 62 263 2.04E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00510 2ab13cb328e27f607a9ce6f6be0693d9 559 Pfam PF01926 50S ribosome-binding GTPase 68 209 7.0E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_19050 fb54aac36a24832555d6c99489315018 188 SMART SM00903 34 178 8.2E-29 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AFR_19050 fb54aac36a24832555d6c99489315018 188 Gene3D G3DSA:2.30.110.10 25 185 1.9E-34 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_19050 fb54aac36a24832555d6c99489315018 188 SUPERFAMILY SSF50475 27 178 1.18E-31 T 12-10-2018 AFR_19050 fb54aac36a24832555d6c99489315018 188 Pfam PF01613 Flavin reductase like domain 37 177 4.5E-25 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AFR_09595 be9a0ed88101456fdc165c2b1ccf667a 293 Pfam PF01636 Phosphotransferase enzyme family 22 237 7.8E-20 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_09595 be9a0ed88101456fdc165c2b1ccf667a 293 SUPERFAMILY SSF56112 3 271 5.54E-35 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_09595 be9a0ed88101456fdc165c2b1ccf667a 293 Gene3D G3DSA:3.90.1200.10 106 285 1.4E-8 T 12-10-2018 AFR_00105 7e5a2ded6d4fde36b8580f919b309909 121 SMART SM00116 4 51 0.012 T 12-10-2018 IPR000644 CBS domain AFR_00105 7e5a2ded6d4fde36b8580f919b309909 121 SMART SM00116 69 117 4.3E-8 T 12-10-2018 IPR000644 CBS domain AFR_00105 7e5a2ded6d4fde36b8580f919b309909 121 Gene3D G3DSA:3.10.580.10 1 117 2.9E-29 T 12-10-2018 AFR_00105 7e5a2ded6d4fde36b8580f919b309909 121 Pfam PF00571 CBS domain 1 47 5.0E-7 T 12-10-2018 IPR000644 CBS domain AFR_00105 7e5a2ded6d4fde36b8580f919b309909 121 Pfam PF00571 CBS domain 64 113 1.3E-10 T 12-10-2018 IPR000644 CBS domain AFR_00105 7e5a2ded6d4fde36b8580f919b309909 121 SUPERFAMILY SSF54631 1 112 1.26E-24 T 12-10-2018 AFR_24030 76bdaf5fc34aaa84ca02632d62843101 277 Gene3D G3DSA:3.20.20.60 16 276 1.8E-68 T 12-10-2018 AFR_24030 76bdaf5fc34aaa84ca02632d62843101 277 Pfam PF13714 Phosphoenolpyruvate phosphomutase 26 254 8.6E-68 T 12-10-2018 AFR_24030 76bdaf5fc34aaa84ca02632d62843101 277 SUPERFAMILY SSF51621 16 263 8.07E-55 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_23645 e5585f5bc8f8d52a12d01d712a1769d6 355 Pfam PF13847 Methyltransferase domain 177 297 5.2E-15 T 12-10-2018 IPR025714 Methyltransferase domain AFR_23645 e5585f5bc8f8d52a12d01d712a1769d6 355 Gene3D G3DSA:3.40.50.150 154 346 6.7E-28 T 12-10-2018 AFR_23645 e5585f5bc8f8d52a12d01d712a1769d6 355 SUPERFAMILY SSF53335 135 354 7.03E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_23645 e5585f5bc8f8d52a12d01d712a1769d6 355 SUPERFAMILY SSF46785 23 95 1.28E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31445 e429495aa61ddd5eed71f2c9dfe27822 158 Pfam PF12802 MarR family 40 100 4.8E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31445 e429495aa61ddd5eed71f2c9dfe27822 158 SMART SM00347 34 137 1.7E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31445 e429495aa61ddd5eed71f2c9dfe27822 158 Gene3D G3DSA:1.10.10.10 9 153 3.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31445 e429495aa61ddd5eed71f2c9dfe27822 158 SUPERFAMILY SSF46785 11 148 4.85E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10720 1554dc3d24ebbd87bc6930d03ee944ca 238 Gene3D G3DSA:3.30.450.40 73 237 1.8E-47 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_10720 1554dc3d24ebbd87bc6930d03ee944ca 238 Pfam PF01614 Bacterial transcriptional regulator 113 234 6.5E-29 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_10720 1554dc3d24ebbd87bc6930d03ee944ca 238 SUPERFAMILY SSF55781 60 236 7.19E-38 T 12-10-2018 AFR_10720 1554dc3d24ebbd87bc6930d03ee944ca 238 SMART SM00346 1 84 0.0014 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_10720 1554dc3d24ebbd87bc6930d03ee944ca 238 SUPERFAMILY SSF46785 2 66 1.02E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10720 1554dc3d24ebbd87bc6930d03ee944ca 238 Pfam PF09339 IclR helix-turn-helix domain 2 48 4.6E-7 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_10720 1554dc3d24ebbd87bc6930d03ee944ca 238 Gene3D G3DSA:1.10.10.10 1 67 7.1E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15425 264a9f681001f68243191357fa25e332 420 SMART SM00387 316 420 1.0E-35 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_15425 264a9f681001f68243191357fa25e332 420 Gene3D G3DSA:1.10.287.130 160 275 4.2E-28 T 12-10-2018 AFR_15425 264a9f681001f68243191357fa25e332 420 SMART SM00304 156 209 1.6E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_15425 264a9f681001f68243191357fa25e332 420 SUPERFAMILY SSF55874 264 419 2.62E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_15425 264a9f681001f68243191357fa25e332 420 SUPERFAMILY SSF47384 193 275 4.12E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_15425 264a9f681001f68243191357fa25e332 420 SMART SM00388 210 275 8.8E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_15425 264a9f681001f68243191357fa25e332 420 Gene3D G3DSA:3.30.565.10 286 420 4.2E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_15425 264a9f681001f68243191357fa25e332 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 2.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_15425 264a9f681001f68243191357fa25e332 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 2.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_15425 264a9f681001f68243191357fa25e332 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 2.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_15425 264a9f681001f68243191357fa25e332 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 275 9.8E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_15425 264a9f681001f68243191357fa25e332 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 419 8.0E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_15425 264a9f681001f68243191357fa25e332 420 Pfam PF00672 HAMP domain 157 205 2.6E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_15425 264a9f681001f68243191357fa25e332 420 SUPERFAMILY SSF158472 159 206 2.75E-7 T 12-10-2018 AFR_24940 e6839e0451b6ff6df9a0efa0f5c6db02 523 Gene3D G3DSA:1.20.1250.20 279 447 7.4E-10 T 12-10-2018 AFR_24940 e6839e0451b6ff6df9a0efa0f5c6db02 523 SUPERFAMILY SSF103473 2 510 1.44E-54 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_24940 e6839e0451b6ff6df9a0efa0f5c6db02 523 Pfam PF07690 Major Facilitator Superfamily 5 416 1.2E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_24940 e6839e0451b6ff6df9a0efa0f5c6db02 523 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 424 2.5E-75 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_24940 e6839e0451b6ff6df9a0efa0f5c6db02 523 Gene3D G3DSA:1.20.1720.10 1 256 3.2E-46 T 12-10-2018 AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 Gene3D G3DSA:2.60.40.1500 475 596 3.3E-16 T 12-10-2018 AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 SUPERFAMILY SSF51011 452 598 3.34E-12 T 12-10-2018 AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 Gene3D G3DSA:2.60.40.10 34 127 1.4E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 Pfam PF01229 Glycosyl hydrolases family 39 146 361 5.3E-50 T 12-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 Pfam PF01229 Glycosyl hydrolases family 39 375 595 2.0E-11 T 12-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 SUPERFAMILY SSF51445 175 460 2.81E-61 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 Gene3D G3DSA:3.20.20.80 164 460 1.8E-80 T 12-10-2018 AFR_21690 2825fe66dd0e9422a329356d660f81f4 599 ProSitePatterns PS01027 Glycosyl hydrolases family 39 active site. 289 298 - T 12-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 SUPERFAMILY SSF52440 7 100 4.89E-24 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 Gene3D G3DSA:3.40.50.20 2 88 2.6E-22 T 12-10-2018 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 Gene3D G3DSA:3.30.470.20 89 311 7.4E-57 T 12-10-2018 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 Pfam PF01820 D-ala D-ala ligase N-terminus 9 90 6.0E-15 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 PIRSF PIRSF039102 40 318 1.8E-67 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 PIRSF PIRSF039102 5 47 4.5E-6 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 Gene3D G3DSA:3.30.1490.20 115 188 7.4E-57 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 SUPERFAMILY SSF56059 100 310 3.71E-45 T 12-10-2018 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 7 315 29.645 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_42955 47bf2f8cb4632337722bd9d0a5018e20 320 Pfam PF07478 D-ala D-ala ligase C-terminus 108 311 2.0E-45 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 Pfam PF07702 UTRA domain 90 225 5.4E-29 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 1.6E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 SMART SM00345 10 67 1.1E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 Gene3D G3DSA:1.10.10.10 1 72 5.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 SUPERFAMILY SSF64288 55 232 1.88E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 Gene3D G3DSA:3.40.1410.10 74 232 9.1E-37 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 6.7E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 6.7E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 SMART SM00866 88 226 4.1E-28 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_35375 346fc454cec7d2598d7c1b5a2b7847be 241 SUPERFAMILY SSF46785 3 71 3.42E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19570 c8f339820873600aea631a9a47ba7245 108 SUPERFAMILY SSF54909 1 91 3.33E-26 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_19570 c8f339820873600aea631a9a47ba7245 108 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.4E-17 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_19570 c8f339820873600aea631a9a47ba7245 108 Gene3D G3DSA:3.30.70.100 3 99 3.1E-20 T 12-10-2018 AFR_39330 e8a827da7442d1572cc0d794c4c59792 219 Pfam PF13398 Peptidase M50B-like 13 208 1.8E-39 T 12-10-2018 AFR_40425 efdecb14e572930a1937ec89c0432a7c 131 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 83 128 4.7E-8 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFR_32520 f51845994ca23e21a8ac308dfb73f829 398 SMART SM00458 33 157 1.5E-26 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_32520 f51845994ca23e21a8ac308dfb73f829 398 Pfam PF00652 Ricin-type beta-trefoil lectin domain 34 154 2.0E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_32520 f51845994ca23e21a8ac308dfb73f829 398 Pfam PF08787 Alginate lyase 179 397 7.2E-59 T 12-10-2018 IPR014895 Alginate lyase 2 AFR_32520 f51845994ca23e21a8ac308dfb73f829 398 SUPERFAMILY SSF50370 37 156 2.57E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_32520 f51845994ca23e21a8ac308dfb73f829 398 Gene3D G3DSA:2.80.10.50 26 157 5.5E-42 T 12-10-2018 AFR_32520 f51845994ca23e21a8ac308dfb73f829 398 SUPERFAMILY SSF49899 179 397 1.69E-56 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_32520 f51845994ca23e21a8ac308dfb73f829 398 Gene3D G3DSA:2.60.120.200 170 398 1.5E-62 T 12-10-2018 AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.2E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 Gene3D G3DSA:1.10.357.10 61 199 5.7E-31 T 12-10-2018 AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 6.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 6.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 SUPERFAMILY SSF48498 91 174 2.39E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 SUPERFAMILY SSF46689 10 88 3.24E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_00165 81ad0567f1c5576b7b3181a9ad6aa1f8 200 Gene3D G3DSA:1.10.10.60 18 59 7.5E-21 T 12-10-2018 AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Gene3D G3DSA:2.60.120.260 880 1021 4.5E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Pfam PF00754 F5/8 type C domain 1038 1150 2.7E-27 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Pfam PF00754 F5/8 type C domain 1173 1285 2.6E-26 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SMART SM00606 891 1021 8.6E-49 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SUPERFAMILY SSF49785 893 1020 6.97E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SUPERFAMILY SSF50952 267 682 1.07E-16 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SMART SM00089 709 794 6.4E-19 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Gene3D G3DSA:2.60.40.10 700 791 6.5E-24 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Pfam PF00801 PKD domain 713 783 4.8E-11 T 12-10-2018 IPR000601 PKD domain AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Pfam PF06283 Trehalose utilisation 30 240 2.4E-82 T 12-10-2018 IPR029010 ThuA-like domain AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SUPERFAMILY SSF52317 28 243 2.29E-46 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SMART SM00231 1023 1157 0.0045 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SMART SM00231 1159 1290 0.028 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SUPERFAMILY SSF49785 1029 1157 1.56E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SUPERFAMILY SSF49299 705 792 7.72E-20 T 12-10-2018 IPR035986 PKD domain superfamily AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Pfam PF07995 Glucose / Sorbosone dehydrogenase 270 545 1.6E-28 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Gene3D G3DSA:3.40.50.880 15 249 2.9E-89 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 SUPERFAMILY SSF49785 1162 1290 7.8E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Gene3D G3DSA:2.60.120.260 1164 1290 4.7E-41 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Gene3D G3DSA:2.60.120.260 1028 1156 2.0E-42 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Gene3D G3DSA:2.120.10.30 255 686 3.7E-60 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_26165 48ec0cb1e718100746123ad673d42d37 1291 Pfam PF03422 Carbohydrate binding module (family 6) 899 1020 1.4E-36 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_09040 ee2bfb77a5904932360483fd82a50250 587 Pfam PF02540 NAD synthase 312 559 4.7E-68 T 12-10-2018 IPR022310 NAD/GMP synthase AFR_09040 ee2bfb77a5904932360483fd82a50250 587 SUPERFAMILY SSF56317 1 262 3.4E-58 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_09040 ee2bfb77a5904932360483fd82a50250 587 Gene3D G3DSA:3.60.110.10 2 306 3.5E-96 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_09040 ee2bfb77a5904932360483fd82a50250 587 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 12-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 AFR_09040 ee2bfb77a5904932360483fd82a50250 587 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 4 585 29.16 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFR_09040 ee2bfb77a5904932360483fd82a50250 587 PIRSF PIRSF006630 1 586 1.3E-199 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFR_09040 ee2bfb77a5904932360483fd82a50250 587 Gene3D G3DSA:3.40.50.620 309 587 1.7E-109 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_09040 ee2bfb77a5904932360483fd82a50250 587 SUPERFAMILY SSF52402 305 568 3.2E-75 T 12-10-2018 AFR_09040 ee2bfb77a5904932360483fd82a50250 587 Pfam PF00795 Carbon-nitrogen hydrolase 5 265 1.1E-25 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFR_09040 ee2bfb77a5904932360483fd82a50250 587 TIGRFAM TIGR00552 nadE: NAD+ synthetase 318 564 2.0E-56 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 AFR_36530 89ba7dbcea2901636897d9ac70d66650 353 Gene3D G3DSA:3.40.718.10 39 284 4.2E-69 T 12-10-2018 AFR_36530 89ba7dbcea2901636897d9ac70d66650 353 PIRSF PIRSF002465 291 346 0.0018 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFR_36530 89ba7dbcea2901636897d9ac70d66650 353 PIRSF PIRSF002465 39 284 5.5E-63 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFR_36530 89ba7dbcea2901636897d9ac70d66650 353 Hamap MF_00019 Phosphate acyltransferase [plsX]. 41 347 60.997 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFR_36530 89ba7dbcea2901636897d9ac70d66650 353 Pfam PF02504 Fatty acid synthesis protein 41 281 4.6E-58 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 AFR_36530 89ba7dbcea2901636897d9ac70d66650 353 SUPERFAMILY SSF53659 41 342 8.63E-57 T 12-10-2018 AFR_06670 ab2226d48b38cfb3f0f06fca65a7de36 398 SMART SM00382 39 185 0.0024 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_06670 ab2226d48b38cfb3f0f06fca65a7de36 398 Gene3D G3DSA:3.40.50.300 26 186 3.9E-24 T 12-10-2018 AFR_06670 ab2226d48b38cfb3f0f06fca65a7de36 398 Pfam PF07728 AAA domain (dynein-related subfamily) 42 175 4.5E-9 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFR_06670 ab2226d48b38cfb3f0f06fca65a7de36 398 SUPERFAMILY SSF52540 27 229 1.51E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16910 0c3ca55cd99452a90823ec30be9baa53 477 Gene3D G3DSA:3.40.309.10 248 441 6.5E-147 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_16910 0c3ca55cd99452a90823ec30be9baa53 477 SUPERFAMILY SSF53720 3 476 4.97E-141 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_16910 0c3ca55cd99452a90823ec30be9baa53 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_16910 0c3ca55cd99452a90823ec30be9baa53 477 Pfam PF00171 Aldehyde dehydrogenase family 17 474 8.6E-143 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_16910 0c3ca55cd99452a90823ec30be9baa53 477 Gene3D G3DSA:3.40.605.10 21 471 6.5E-147 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_01665 fa5f374ca904202f8ad7acc13c03a12d 230 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 89 209 2.6E-44 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01665 fa5f374ca904202f8ad7acc13c03a12d 230 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 73 218 29.094 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01665 fa5f374ca904202f8ad7acc13c03a12d 230 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 90 210 7.4E-44 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01665 fa5f374ca904202f8ad7acc13c03a12d 230 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 139 199 5.0E-17 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01665 fa5f374ca904202f8ad7acc13c03a12d 230 Gene3D G3DSA:3.30.460.80 43 190 9.0E-48 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01665 fa5f374ca904202f8ad7acc13c03a12d 230 SUPERFAMILY SSF143243 70 226 4.58E-49 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_39055 15a7eed5128917760f1f0676179fa72d 166 SMART SM00347 35 138 8.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_39055 15a7eed5128917760f1f0676179fa72d 166 Gene3D G3DSA:1.10.10.10 9 152 2.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39055 15a7eed5128917760f1f0676179fa72d 166 Pfam PF12802 MarR family 42 101 3.3E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_39055 15a7eed5128917760f1f0676179fa72d 166 SUPERFAMILY SSF46785 9 150 4.7E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF56801 428 970 1.3E-146 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.10 14 379 2.6E-134 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00501 AMP-binding enzyme 4566 4944 3.7E-95 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00501 AMP-binding enzyme 3547 3917 5.5E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00501 AMP-binding enzyme 1504 1873 1.1E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00501 AMP-binding enzyme 467 855 2.3E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00501 AMP-binding enzyme 2524 2902 9.9E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00501 AMP-binding enzyme 5598 5989 7.8E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 6172 6370 1.45E-29 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.10 5132 5500 2.3E-154 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 6490 6653 4.4E-36 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2544 2926 5.1E-126 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4586 4968 1.0E-124 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 488 879 1.3E-122 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3568 3941 5.7E-118 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1525 1897 9.3E-119 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5618 6013 5.2E-131 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 2055 2252 7.0E-46 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 192 431 9.34E-55 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.300.30 5983 6086 2.5E-35 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.300.30 3912 4008 3.4E-34 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.40.50.12780 2511 2896 2.1E-131 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.40.50.12780 4553 4938 1.4E-130 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.40.50.12780 1491 1867 6.3E-129 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.40.50.12780 453 849 1.3E-127 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.40.50.12780 5584 5982 3.3E-139 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.40.50.12780 3534 3911 2.1E-128 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF56801 4524 5059 2.49E-151 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5734 5745 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 5313 5583 6.56E-61 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3671 3682 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1628 1639 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF56801 3507 4032 2.22E-144 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF47336 4012 4085 1.22E-18 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF56801 2482 3017 5.49E-152 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.30 1220 1470 4.5E-160 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.10 1045 1415 4.5E-160 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF47336 1968 2040 4.45E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.10 2061 2431 8.2E-154 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF56801 5557 6109 4.45E-154 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.10 6166 6341 1.0E-45 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 1047 1216 3.34E-51 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF47336 6090 6160 1.07E-18 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF47336 950 1022 6.67E-20 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 7 206 3.11E-43 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 981 996 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SMART SM01294 6097 6160 0.0074 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00550 Phosphopantetheine attachment site 1977 2040 3.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00550 Phosphopantetheine attachment site 6098 6157 5.7E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00550 Phosphopantetheine attachment site 3006 3067 2.3E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00550 Phosphopantetheine attachment site 4021 4084 4.4E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00550 Phosphopantetheine attachment site 5048 5110 9.0E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00550 Phosphopantetheine attachment site 959 1022 8.1E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 1223 1490 3.45E-62 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1999 2014 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.30 6343 6632 3.2E-87 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3028 3043 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4043 4058 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SMART SM00823 Phosphopantetheine attachment site 3004 3073 1.0E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SMART SM00823 Phosphopantetheine attachment site 4019 4088 1.9E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SMART SM00823 Phosphopantetheine attachment site 6096 6164 4.4E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SMART SM00823 Phosphopantetheine attachment site 1975 2044 1.4E-8 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SMART SM00823 Phosphopantetheine attachment site 5046 5115 1.5E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SMART SM00823 Phosphopantetheine attachment site 957 1026 6.9E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 2238 2510 5.34E-59 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF47336 5040 5112 2.09E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.300.30 850 944 2.4E-32 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.300.30 1868 1962 8.2E-34 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.300.30 4939 5034 2.1E-32 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.300.30 2897 2992 2.6E-32 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2654 2665 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 3268 3535 7.0E-63 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.30 192 444 2.6E-134 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF56801 1464 1988 8.77E-147 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 5134 5306 1.33E-48 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 6359 6630 2.22E-36 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 4282 4553 9.34E-62 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4696 4707 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 4106 4276 7.78E-48 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF52777 3090 3262 1.33E-44 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF13193 AMP-binding enzyme C-terminal domain 1881 1950 1.8E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF13193 AMP-binding enzyme C-terminal domain 863 932 8.6E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF13193 AMP-binding enzyme C-terminal domain 5997 6072 2.5E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF13193 AMP-binding enzyme C-terminal domain 4952 5021 1.0E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF13193 AMP-binding enzyme C-terminal domain 2910 2979 1.1E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF13193 AMP-binding enzyme C-terminal domain 3925 3994 1.4E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.30 5310 5563 2.3E-154 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 SUPERFAMILY SSF47336 2997 3068 1.44E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:1.10.1200.10 5035 5116 1.5E-28 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:1.10.1200.10 1963 2045 5.0E-29 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:1.10.1200.10 4009 4089 2.3E-27 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:1.10.1200.10 6087 6165 1.6E-24 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:1.10.1200.10 945 1029 3.0E-29 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:1.10.1200.10 2993 3077 2.0E-29 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.10 3089 3457 3.7E-155 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6120 6135 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5070 5085 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.30 4280 4531 5.9E-156 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.30 2236 2489 8.2E-154 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00668 Condensation domain 1043 1481 1.8E-100 T 12-10-2018 IPR001242 Condensation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00668 Condensation domain 4103 4546 1.6E-97 T 12-10-2018 IPR001242 Condensation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00668 Condensation domain 2060 2503 1.0E-95 T 12-10-2018 IPR001242 Condensation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00668 Condensation domain 6194 6540 5.4E-45 T 12-10-2018 IPR001242 Condensation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00668 Condensation domain 3087 3525 1.0E-95 T 12-10-2018 IPR001242 Condensation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00668 Condensation domain 5131 5578 9.1E-95 T 12-10-2018 IPR001242 Condensation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Pfam PF00668 Condensation domain 9 446 2.6E-81 T 12-10-2018 IPR001242 Condensation domain AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.30 3266 3513 3.7E-155 T 12-10-2018 AFR_18545 eb04097aad35bab5054db850f9cf46cf 6661 Gene3D G3DSA:3.30.559.10 4105 4475 5.9E-156 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_30635 fb102d5c081cd89335d1e8ad3e6ccc39 194 SUPERFAMILY SSF53271 15 180 5.38E-42 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_30635 fb102d5c081cd89335d1e8ad3e6ccc39 194 Gene3D G3DSA:3.40.50.2020 5 192 1.8E-60 T 12-10-2018 AFR_30635 fb102d5c081cd89335d1e8ad3e6ccc39 194 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 15 188 34.205 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 AFR_30635 fb102d5c081cd89335d1e8ad3e6ccc39 194 Pfam PF00156 Phosphoribosyl transferase domain 19 159 2.0E-23 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFR_35355 5588f8d40d94b3d3f565abd4a697343c 327 Pfam PF00294 pfkB family carbohydrate kinase 12 324 7.2E-38 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_35355 5588f8d40d94b3d3f565abd4a697343c 327 SUPERFAMILY SSF53613 11 326 7.79E-54 T 12-10-2018 IPR029056 Ribokinase-like AFR_35355 5588f8d40d94b3d3f565abd4a697343c 327 Gene3D G3DSA:3.40.1190.20 11 327 2.5E-54 T 12-10-2018 IPR029056 Ribokinase-like AFR_35355 5588f8d40d94b3d3f565abd4a697343c 327 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 281 294 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_09530 cf65b09b43f06bbe4d6d0fb6bee5f2f2 137 PIRSF PIRSF030042 9 136 2.0E-12 T 12-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 AFR_09530 cf65b09b43f06bbe4d6d0fb6bee5f2f2 137 Pfam PF14340 Domain of unknown function (DUF4395) 4 131 1.6E-41 T 12-10-2018 IPR025508 Domain of unknown function DUF4395 AFR_10495 bcef5ad7d7027e8daa11d50b3fa5c088 266 Pfam PF01464 Transglycosylase SLT domain 121 241 1.0E-14 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFR_10495 bcef5ad7d7027e8daa11d50b3fa5c088 266 SUPERFAMILY SSF53955 117 256 2.39E-17 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_10495 bcef5ad7d7027e8daa11d50b3fa5c088 266 Gene3D G3DSA:1.10.530.10 101 261 1.1E-23 T 12-10-2018 AFR_39995 2b120ffee5636a868810f1d6757e2003 659 Gene3D G3DSA:3.80.30.30 470 609 2.8E-6 T 12-10-2018 AFR_39995 2b120ffee5636a868810f1d6757e2003 659 SMART SM00305 339 381 1.9E-4 T 12-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_39995 2b120ffee5636a868810f1d6757e2003 659 SMART SM00306 82 178 6.4E-7 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_39995 2b120ffee5636a868810f1d6757e2003 659 Gene3D G3DSA:2.170.16.10 84 187 4.6E-14 T 12-10-2018 AFR_39995 2b120ffee5636a868810f1d6757e2003 659 SUPERFAMILY SSF102114 440 576 2.35E-5 T 12-10-2018 AFR_39995 2b120ffee5636a868810f1d6757e2003 659 SUPERFAMILY SSF51294 84 375 6.41E-19 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_20150 7c62507c1688f97196ffa2796b151055 112 Gene3D G3DSA:1.10.10.10 1 58 8.2E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20150 7c62507c1688f97196ffa2796b151055 112 Pfam PF03965 Penicillinase repressor 1 92 2.9E-23 T 12-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 AFR_20150 7c62507c1688f97196ffa2796b151055 112 SUPERFAMILY SSF46785 1 93 6.0E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_12380 098febb92736bfd159e2dfb8df946248 719 ProSitePatterns PS00436 Peroxidases active site signature. 83 94 - T 12-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 Hamap MF_01961 Catalase-peroxidase [katG]. 2 719 40.721 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00458 Haem peroxidase superfamily signature 246 261 1.3E-19 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00458 Haem peroxidase superfamily signature 305 320 1.3E-19 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00458 Haem peroxidase superfamily signature 83 97 1.3E-19 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00458 Haem peroxidase superfamily signature 161 173 1.3E-19 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00458 Haem peroxidase superfamily signature 143 160 1.3E-19 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 SUPERFAMILY SSF48113 419 718 5.45E-101 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 Gene3D G3DSA:1.10.520.10 422 718 1.3E-134 T 12-10-2018 AFR_12380 098febb92736bfd159e2dfb8df946248 719 Gene3D G3DSA:1.10.420.20 183 386 4.7E-211 T 12-10-2018 AFR_12380 098febb92736bfd159e2dfb8df946248 719 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 246 256 - T 12-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 AFR_12380 098febb92736bfd159e2dfb8df946248 719 Gene3D G3DSA:1.10.520.10 14 419 4.7E-211 T 12-10-2018 AFR_12380 098febb92736bfd159e2dfb8df946248 719 SUPERFAMILY SSF48113 13 418 3.24E-153 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 Gene3D G3DSA:1.10.420.10 571 694 1.3E-134 T 12-10-2018 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 469 495 9.3E-53 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 45 58 9.3E-53 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 19 41 9.3E-53 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 254 277 9.3E-53 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_12380 098febb92736bfd159e2dfb8df946248 719 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 60 85 9.3E-53 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_12380 098febb92736bfd159e2dfb8df946248 719 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 6 718 0.0 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_12380 098febb92736bfd159e2dfb8df946248 719 Pfam PF00141 Peroxidase 391 693 2.3E-32 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_12380 098febb92736bfd159e2dfb8df946248 719 Pfam PF00141 Peroxidase 70 384 1.3E-48 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 SMART SM00354 2 72 2.3E-28 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.7E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 SUPERFAMILY SSF47413 2 60 2.91E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 Pfam PF13377 Periplasmic binding protein-like domain 165 323 1.5E-35 T 12-10-2018 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 Gene3D G3DSA:1.10.260.40 1 55 1.1E-21 T 12-10-2018 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 SUPERFAMILY SSF53822 63 327 1.85E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 Gene3D G3DSA:3.40.50.2300 157 282 2.1E-73 T 12-10-2018 AFR_20535 38f6cabd164fac75ea7fbd8b314a40d2 329 Gene3D G3DSA:3.40.50.2300 56 298 2.1E-73 T 12-10-2018 AFR_20530 8e563d0fa858bee9342bdd1386e5e209 405 Gene3D G3DSA:3.40.190.10 164 298 4.9E-15 T 12-10-2018 AFR_20530 8e563d0fa858bee9342bdd1386e5e209 405 SUPERFAMILY SSF53850 48 394 1.03E-26 T 12-10-2018 AFR_20530 8e563d0fa858bee9342bdd1386e5e209 405 Pfam PF13416 Bacterial extracellular solute-binding protein 65 350 3.6E-26 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_20530 8e563d0fa858bee9342bdd1386e5e209 405 Gene3D G3DSA:3.40.190.10 63 345 4.9E-15 T 12-10-2018 AFR_01330 506d21fc7cba99a83e71f85bccc1e629 187 SUPERFAMILY SSF52833 51 184 3.67E-28 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_01330 506d21fc7cba99a83e71f85bccc1e629 187 Gene3D G3DSA:3.40.30.10 39 184 1.2E-30 T 12-10-2018 AFR_01330 506d21fc7cba99a83e71f85bccc1e629 187 Pfam PF00578 AhpC/TSA family 50 162 1.3E-19 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_38610 1c7c869a390ab75f956e424394f83b8b 398 SUPERFAMILY SSF55931 15 380 9.81E-40 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_38610 1c7c869a390ab75f956e424394f83b8b 398 Gene3D G3DSA:3.30.590.20 5 390 1.5E-100 T 12-10-2018 AFR_38610 1c7c869a390ab75f956e424394f83b8b 398 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 1 394 32.025 T 12-10-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_38610 1c7c869a390ab75f956e424394f83b8b 398 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 53 327 7.4E-52 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_38610 1c7c869a390ab75f956e424394f83b8b 398 PIRSF PIRSF017901 2 395 4.2E-101 T 12-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_38610 1c7c869a390ab75f956e424394f83b8b 398 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 10 386 2.3E-125 T 12-10-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_29660 9a80705c28d37c48a2365489c5ff4b1c 261 SUPERFAMILY SSF53335 16 252 1.53E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_29660 9a80705c28d37c48a2365489c5ff4b1c 261 Pfam PF04672 S-adenosyl methyltransferase 7 260 5.3E-82 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_29660 9a80705c28d37c48a2365489c5ff4b1c 261 Gene3D G3DSA:3.40.50.150 2 260 1.3E-87 T 12-10-2018 AFR_29660 9a80705c28d37c48a2365489c5ff4b1c 261 PIRSF PIRSF017393 1 261 1.0E-90 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_25890 66b54f585785c23c3852e7eacc830907 894 SUPERFAMILY SSF50952 495 891 9.94E-15 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_25890 66b54f585785c23c3852e7eacc830907 894 Pfam PF07995 Glucose / Sorbosone dehydrogenase 589 710 5.9E-5 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_25890 66b54f585785c23c3852e7eacc830907 894 SUPERFAMILY SSF49785 33 193 1.96E-26 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25890 66b54f585785c23c3852e7eacc830907 894 Pfam PF13205 Bacterial Ig-like domain 364 470 1.5E-14 T 12-10-2018 IPR032812 SbsA, Ig-like domain AFR_25890 66b54f585785c23c3852e7eacc830907 894 SUPERFAMILY SSF49785 199 360 2.21E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25890 66b54f585785c23c3852e7eacc830907 894 Gene3D G3DSA:2.120.10.30 483 714 6.0E-16 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_25890 66b54f585785c23c3852e7eacc830907 894 Gene3D G3DSA:2.60.120.430 196 364 7.9E-12 T 12-10-2018 AFR_25890 66b54f585785c23c3852e7eacc830907 894 Gene3D G3DSA:2.60.120.430 18 195 5.9E-14 T 12-10-2018 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 Gene3D G3DSA:3.40.50.12740 5 215 2.4E-65 T 12-10-2018 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 209 5.6E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 SMART SM00448 5 118 3.7E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 Pfam PF00072 Response regulator receiver domain 7 117 8.1E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 SMART SM00421 152 209 1.1E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 SUPERFAMILY SSF46894 151 216 2.75E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_30125 341c49980409d457d486c4cf6881eb6d 217 SUPERFAMILY SSF52172 4 126 9.11E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_09960 9bb006b713d5a53c10cdef14b6f5c4b3 378 Pfam PF08353 Domain of unknown function (DUF1727) 270 367 1.1E-19 T 12-10-2018 IPR013564 Domain of unknown function DUF1727 AFR_09960 9bb006b713d5a53c10cdef14b6f5c4b3 378 Gene3D G3DSA:3.40.1190.10 12 253 4.8E-34 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_09960 9bb006b713d5a53c10cdef14b6f5c4b3 378 SUPERFAMILY SSF53623 12 247 5.65E-31 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_09960 9bb006b713d5a53c10cdef14b6f5c4b3 378 Pfam PF08245 Mur ligase middle domain 27 232 5.8E-15 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 TIGRFAM TIGR00433 bioB: biotin synthase 29 322 5.3E-104 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 Hamap MF_01694 Biotin synthase [bioB]. 15 325 37.464 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 320 2.0E-11 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 SUPERFAMILY SSF102114 19 310 1.96E-64 T 12-10-2018 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 Pfam PF04055 Radical SAM superfamily 64 220 8.8E-13 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 Gene3D G3DSA:3.20.20.70 22 326 2.3E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 SMART SM00876 232 324 3.9E-28 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 SMART SM00729 57 267 1.2E-33 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_34955 b5d9efa771c967d87eae5d5d5133bce7 331 PIRSF PIRSF001619 2 330 1.9E-103 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFR_03205 668aa80fe4e9dcaa8817296193b8971b 740 Pfam PF00754 F5/8 type C domain 55 168 8.6E-27 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_03205 668aa80fe4e9dcaa8817296193b8971b 740 SUPERFAMILY SSF51126 449 712 5.02E-5 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_03205 668aa80fe4e9dcaa8817296193b8971b 740 Gene3D G3DSA:2.60.120.260 47 176 3.3E-38 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_03205 668aa80fe4e9dcaa8817296193b8971b 740 SUPERFAMILY SSF49785 50 174 7.8E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_04530 17db88a2878dd3e92f50de66622883a7 153 ProSitePatterns PS00464 Ribosomal protein L22 signature. 93 117 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04530 17db88a2878dd3e92f50de66622883a7 153 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 11 120 29.671 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04530 17db88a2878dd3e92f50de66622883a7 153 SUPERFAMILY SSF54843 13 119 2.49E-42 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04530 17db88a2878dd3e92f50de66622883a7 153 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 15 117 4.1E-46 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04530 17db88a2878dd3e92f50de66622883a7 153 Pfam PF00237 Ribosomal protein L22p/L17e 15 117 2.0E-37 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AFR_04530 17db88a2878dd3e92f50de66622883a7 153 Gene3D G3DSA:3.90.470.10 12 148 3.3E-48 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SUPERFAMILY SSF47384 392 465 2.16E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SUPERFAMILY SSF55874 457 630 1.57E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 126 249 1.2E-23 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 248 375 2.7E-15 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 127 1.9E-16 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Gene3D G3DSA:3.30.565.10 469 636 2.1E-47 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00086 80 121 30.0 T 12-10-2018 IPR001610 PAC motif AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00086 331 371 1.1 T 12-10-2018 IPR001610 PAC motif AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00086 201 243 10.0 T 12-10-2018 IPR001610 PAC motif AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Gene3D G3DSA:3.40.50.2300 647 768 9.9E-26 T 12-10-2018 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SUPERFAMILY SSF52172 649 767 3.27E-28 T 12-10-2018 IPR011006 CheY-like superfamily AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00387 508 631 1.1E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Pfam PF00512 His Kinase A (phospho-acceptor) domain 402 465 9.4E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 509 630 5.0E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00388 402 467 6.6E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Pfam PF00072 Response regulator receiver domain 653 762 4.8E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Gene3D G3DSA:3.30.450.20 5 121 6.6E-21 T 12-10-2018 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Pfam PF13426 PAS domain 16 117 1.6E-9 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SUPERFAMILY SSF55785 121 241 1.31E-21 T 12-10-2018 IPR035965 PAS domain superfamily AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Pfam PF08448 PAS fold 137 245 1.8E-11 T 12-10-2018 IPR013656 PAS fold-4 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00448 651 762 7.8E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 591 609 1.4E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 588 1.4E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 574 1.4E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 628 1.4E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Gene3D G3DSA:3.30.450.20 122 245 5.9E-24 T 12-10-2018 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00091 129 194 3.0E-9 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00091 336 402 180.0 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00091 248 313 2.3E-8 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SMART SM00091 6 71 2.2E-6 T 12-10-2018 IPR000014 PAS domain AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SUPERFAMILY SSF55785 17 127 1.31E-20 T 12-10-2018 IPR035965 PAS domain superfamily AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Gene3D G3DSA:3.30.450.20 246 369 9.6E-22 T 12-10-2018 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 SUPERFAMILY SSF55785 242 369 1.01E-16 T 12-10-2018 IPR035965 PAS domain superfamily AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Pfam PF00989 PAS fold 249 366 2.3E-9 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_24175 48fcbcbbf804c1ea5c51484215dd3c94 768 Gene3D G3DSA:1.10.287.130 394 465 3.2E-17 T 12-10-2018 AFR_06335 afeaf12ef6f820aef59ff5b70a842b43 286 Gene3D G3DSA:3.20.20.100 1 286 2.5E-78 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_06335 afeaf12ef6f820aef59ff5b70a842b43 286 Pfam PF00248 Aldo/keto reductase family 14 285 3.6E-59 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_06335 afeaf12ef6f820aef59ff5b70a842b43 286 SUPERFAMILY SSF51430 1 286 8.77E-74 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 Gene3D G3DSA:3.40.50.920 510 616 1.1E-18 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 SUPERFAMILY SSF52922 512 615 1.27E-13 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 259 476 1.9E-53 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 22 210 3.1E-23 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 Gene3D G3DSA:3.40.920.10 10 216 7.2E-13 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 SUPERFAMILY SSF52518 234 498 1.05E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 SUPERFAMILY SSF53323 16 253 6.93E-16 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 14 607 1.1E-197 T 12-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 AFR_40125 6ef90d98bdc2597fdb9602cdc0ea60ca 617 Gene3D G3DSA:3.40.50.970 221 426 1.1E-66 T 12-10-2018 AFR_27565 867ffb763f7c2586cef9a6bb3d5f00f0 331 Gene3D G3DSA:3.20.20.30 1 329 7.4E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_27565 867ffb763f7c2586cef9a6bb3d5f00f0 331 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 329 2.0E-175 T 12-10-2018 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 AFR_27565 867ffb763f7c2586cef9a6bb3d5f00f0 331 Pfam PF00296 Luciferase-like monooxygenase 13 305 4.1E-58 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_27565 867ffb763f7c2586cef9a6bb3d5f00f0 331 SUPERFAMILY SSF51679 1 328 4.06E-63 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_21075 fde7efaa8b0c27f364126c8ff9847aa3 395 Pfam PF05949 Bacterial protein of unknown function (DUF881) 252 391 2.4E-29 T 12-10-2018 IPR010273 Protein of unknown function DUF881 AFR_21075 fde7efaa8b0c27f364126c8ff9847aa3 395 Gene3D G3DSA:3.30.70.1880 250 395 2.0E-36 T 12-10-2018 AFR_20655 0f7687883a5044d7f8ca82143759cc72 196 SUPERFAMILY SSF55729 4 194 1.2E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_20655 0f7687883a5044d7f8ca82143759cc72 196 Gene3D G3DSA:3.40.630.30 1 196 1.6E-41 T 12-10-2018 AFR_20655 0f7687883a5044d7f8ca82143759cc72 196 Pfam PF13508 Acetyltransferase (GNAT) domain 122 175 7.4E-9 T 12-10-2018 IPR000182 GNAT domain AFR_32245 273361e728724d71a48517a8d10f3e32 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 5.2E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_32245 273361e728724d71a48517a8d10f3e32 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 5.2E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_32245 273361e728724d71a48517a8d10f3e32 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 5.2E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_32245 273361e728724d71a48517a8d10f3e32 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 212 226 5.2E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_32245 273361e728724d71a48517a8d10f3e32 268 Pfam PF12697 Alpha/beta hydrolase family 22 260 5.2E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_32245 273361e728724d71a48517a8d10f3e32 268 SUPERFAMILY SSF53474 4 266 7.14E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32245 273361e728724d71a48517a8d10f3e32 268 Gene3D G3DSA:3.40.50.1820 3 267 9.4E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32245 273361e728724d71a48517a8d10f3e32 268 PRINTS PR00412 Epoxide hydrolase signature 243 265 1.4E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_32245 273361e728724d71a48517a8d10f3e32 268 PRINTS PR00412 Epoxide hydrolase signature 210 226 1.4E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_32245 273361e728724d71a48517a8d10f3e32 268 PRINTS PR00412 Epoxide hydrolase signature 47 62 1.4E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2075 2299 7.7E-28 T 12-10-2018 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF51735 1896 2046 2.48E-9 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:1.10.1200.10 1766 1862 7.3E-21 T 12-10-2018 IPR036736 ACP-like superfamily AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:1.10.1200.10 1663 1756 5.4E-21 T 12-10-2018 IPR036736 ACP-like superfamily AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF52151 1193 1491 4.19E-48 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF47336 1778 1881 8.06E-10 T 12-10-2018 IPR036736 ACP-like superfamily AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:3.40.47.10 640 1163 5.0E-163 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF51735 2073 2333 1.0E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:3.20.20.70 268 629 7.3E-65 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:3.20.20.70 6 266 1.3E-26 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF51412 10 200 3.94E-13 T 12-10-2018 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 825 841 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Pfam PF00698 Acyl transferase domain 1195 1476 1.8E-21 T 12-10-2018 IPR014043 Acyl transferase AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1047 1128 1.5E-8 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 644 912 3.6E-69 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:3.40.50.720 1931 2350 4.5E-76 T 12-10-2018 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF47336 1675 1768 2.73E-9 T 12-10-2018 IPR036736 ACP-like superfamily AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SMART SM00825 Beta-ketoacyl synthase 645 1090 9.2E-117 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF51412 269 535 1.07E-13 T 12-10-2018 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF55048 1322 1387 6.15E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:3.40.366.10 1194 1477 1.3E-70 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Gene3D G3DSA:3.30.70.250 1318 1388 1.3E-70 T 12-10-2018 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Pfam PF08659 KR domain 2076 2297 6.0E-34 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 920 1037 6.6E-35 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1196 1497 7.2E-20 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain AFR_39765 90f124f1938682dc6322c7d1fbe7a39d 2352 SUPERFAMILY SSF53901 641 1080 1.5E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 192 1.4E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 Gene3D G3DSA:3.10.450.50 204 304 3.5E-14 T 12-10-2018 AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 Pfam PF08281 Sigma-70, region 4 138 189 6.6E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 SUPERFAMILY SSF88659 130 191 2.99E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 15 312 3.2E-90 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 Pfam PF04542 Sigma-70 region 2 25 90 3.0E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 Pfam PF12680 SnoaL-like domain 208 276 3.3E-9 T 12-10-2018 IPR037401 SnoaL-like domain AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 SUPERFAMILY SSF54427 205 300 3.06E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 Gene3D G3DSA:1.10.1740.10 2 107 8.3E-29 T 12-10-2018 AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 SUPERFAMILY SSF88946 6 99 1.22E-26 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24805 7795762a43c3cb9e65f29a03f6d1b48b 314 Gene3D G3DSA:1.10.10.10 119 193 2.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19455 869b59ad589c1a0a46ed2fbf44173630 620 Pfam PF13462 Thioredoxin 451 608 2.9E-26 T 12-10-2018 IPR012336 Thioredoxin-like fold AFR_19455 869b59ad589c1a0a46ed2fbf44173630 620 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 15 429 18.811 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_19455 869b59ad589c1a0a46ed2fbf44173630 620 Gene3D G3DSA:1.20.1530.10 13 424 6.9E-111 T 12-10-2018 IPR023171 Na/H antiporter domain superfamily AFR_19455 869b59ad589c1a0a46ed2fbf44173630 620 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 18 412 5.1E-83 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_19455 869b59ad589c1a0a46ed2fbf44173630 620 Gene3D G3DSA:3.40.30.10 445 612 2.7E-49 T 12-10-2018 AFR_19455 869b59ad589c1a0a46ed2fbf44173630 620 SUPERFAMILY SSF52833 447 608 1.22E-44 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_19455 869b59ad589c1a0a46ed2fbf44173630 620 Pfam PF06965 Na+/H+ antiporter 1 17 417 8.5E-118 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_36700 95d87a83a5a225038c397ffb0326ea71 228 SMART SM00346 4 88 4.6E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_36700 95d87a83a5a225038c397ffb0326ea71 228 Gene3D G3DSA:3.30.450.40 70 228 2.2E-37 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_36700 95d87a83a5a225038c397ffb0326ea71 228 Pfam PF09339 IclR helix-turn-helix domain 13 53 1.4E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_36700 95d87a83a5a225038c397ffb0326ea71 228 Gene3D G3DSA:1.10.10.10 3 69 4.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36700 95d87a83a5a225038c397ffb0326ea71 228 Pfam PF01614 Bacterial transcriptional regulator 120 221 5.4E-17 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_36700 95d87a83a5a225038c397ffb0326ea71 228 SUPERFAMILY SSF55781 75 226 1.31E-34 T 12-10-2018 AFR_36700 95d87a83a5a225038c397ffb0326ea71 228 SUPERFAMILY SSF46785 7 71 7.08E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16160 5f2c7a642da9d8d0249f84251656d887 271 SUPERFAMILY SSF54593 20 176 2.75E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16160 5f2c7a642da9d8d0249f84251656d887 271 Gene3D G3DSA:3.10.180.10 1 127 7.5E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16160 5f2c7a642da9d8d0249f84251656d887 271 Gene3D G3DSA:3.10.180.10 128 269 1.8E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16160 5f2c7a642da9d8d0249f84251656d887 271 SUPERFAMILY SSF54593 139 268 3.44E-15 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_26250 78dbb2804a6975dc47e26f27aacc888e 216 SMART SM00240 128 186 1.1E-6 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFR_26250 78dbb2804a6975dc47e26f27aacc888e 216 SUPERFAMILY SSF49879 118 210 1.57E-18 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 AFR_26250 78dbb2804a6975dc47e26f27aacc888e 216 Gene3D G3DSA:2.60.200.20 105 215 3.1E-18 T 12-10-2018 AFR_26250 78dbb2804a6975dc47e26f27aacc888e 216 Pfam PF00498 FHA domain 129 205 2.4E-11 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFR_05830 bf1355174ebe9eb0e02e27e6bfaa4f8e 542 Gene3D G3DSA:3.40.605.10 14 527 4.9E-195 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_05830 bf1355174ebe9eb0e02e27e6bfaa4f8e 542 SUPERFAMILY SSF53720 8 527 6.81E-124 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_05830 bf1355174ebe9eb0e02e27e6bfaa4f8e 542 Pfam PF00171 Aldehyde dehydrogenase family 55 520 1.2E-100 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_05830 bf1355174ebe9eb0e02e27e6bfaa4f8e 542 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_05830 bf1355174ebe9eb0e02e27e6bfaa4f8e 542 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 541 1.2E-232 T 12-10-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 AFR_05830 bf1355174ebe9eb0e02e27e6bfaa4f8e 542 Gene3D G3DSA:3.40.309.10 297 495 4.9E-195 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_09655 b3e0fbd9bce35a6a74b993f244c2f1f2 339 Gene3D G3DSA:3.40.640.10 1 246 5.0E-78 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_09655 b3e0fbd9bce35a6a74b993f244c2f1f2 339 PIRSF PIRSF017617 1 339 6.8E-118 T 12-10-2018 IPR023603 Threonine aldolase AFR_09655 b3e0fbd9bce35a6a74b993f244c2f1f2 339 SUPERFAMILY SSF53383 2 338 5.18E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_09655 b3e0fbd9bce35a6a74b993f244c2f1f2 339 Gene3D G3DSA:3.90.1150.10 248 339 1.9E-19 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_09655 b3e0fbd9bce35a6a74b993f244c2f1f2 339 Pfam PF01212 Beta-eliminating lyase 3 282 3.3E-79 T 12-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 AFR_16400 aeab852eab1e3eb26923f475a9c91978 244 Pfam PF01738 Dienelactone hydrolase family 18 241 1.3E-30 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFR_16400 aeab852eab1e3eb26923f475a9c91978 244 Gene3D G3DSA:3.40.50.1820 4 242 6.2E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16400 aeab852eab1e3eb26923f475a9c91978 244 SUPERFAMILY SSF53474 7 242 3.6E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_40190 eda0b117b712a9f84cb136a11ef758a5 213 Gene3D G3DSA:3.40.50.1000 7 196 5.4E-18 T 12-10-2018 IPR023214 HAD superfamily AFR_40190 eda0b117b712a9f84cb136a11ef758a5 213 Gene3D G3DSA:1.10.150.240 18 83 5.4E-18 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_40190 eda0b117b712a9f84cb136a11ef758a5 213 SUPERFAMILY SSF56784 5 205 8.55E-23 T 12-10-2018 IPR036412 HAD-like superfamily AFR_40190 eda0b117b712a9f84cb136a11ef758a5 213 Pfam PF13242 HAD-hyrolase-like 148 206 2.8E-6 T 12-10-2018 AFR_41220 6c48aa2f712b6f48982e4de9ecf786f5 384 SUPERFAMILY SSF51182 7 383 7.6E-94 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_41220 6c48aa2f712b6f48982e4de9ecf786f5 384 Pfam PF04209 homogentisate 1,2-dioxygenase 114 382 4.7E-17 T 12-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 AFR_41220 6c48aa2f712b6f48982e4de9ecf786f5 384 Gene3D G3DSA:2.60.120.10 82 171 8.2E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_41220 6c48aa2f712b6f48982e4de9ecf786f5 384 Gene3D G3DSA:2.60.120.10 266 361 3.4E-7 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_19310 b93a0af7e2d4b425eed4991bf8c38c4a 284 Gene3D G3DSA:1.10.3720.10 78 270 1.5E-21 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19310 b93a0af7e2d4b425eed4991bf8c38c4a 284 SUPERFAMILY SSF161098 82 260 1.31E-26 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19310 b93a0af7e2d4b425eed4991bf8c38c4a 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 263 6.9E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_33240 b09ba01fcd903785640384dd30e1118a 244 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 97 168 4.0E-10 T 12-10-2018 AFR_33240 b09ba01fcd903785640384dd30e1118a 244 SUPERFAMILY SSF53335 72 214 5.52E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_33240 b09ba01fcd903785640384dd30e1118a 244 Gene3D G3DSA:3.40.50.150 62 230 4.7E-26 T 12-10-2018 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 SUPERFAMILY SSF55920 6 284 3.4E-88 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 Pfam PF00557 Metallopeptidase family M24 48 276 3.8E-52 T 12-10-2018 IPR000994 Peptidase M24 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 7.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 7.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 7.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 7.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 8.1E-93 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 Gene3D G3DSA:3.90.230.10 4 285 3.1E-117 T 12-10-2018 AFR_36015 92d0d4686e368efc912c41f48f7a8435 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.496 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 302 6.0E-26 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 Gene3D G3DSA:1.10.150.20 226 326 1.4E-28 T 12-10-2018 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 SUPERFAMILY SSF55257 9 220 2.94E-24 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 SMART SM00662 18 225 3.0E-87 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 SUPERFAMILY SSF56553 48 169 1.44E-40 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 322 6.0E-28 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 33.995 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 4.2E-23 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 5.4E-111 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 Gene3D G3DSA:2.170.120.12 48 168 8.5E-81 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.5E-18 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 SUPERFAMILY SSF47789 247 319 1.16E-23 T 12-10-2018 AFR_04655 03eb71696dc5d9a721df0b4bd481ddc3 340 Gene3D G3DSA:3.30.1360.10 13 217 8.5E-81 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_24695 4e1bf4805c7c91f2384c2e36ff12c5f7 153 Gene3D G3DSA:3.30.530.20 2 151 1.2E-41 T 12-10-2018 IPR023393 START-like domain superfamily AFR_24695 4e1bf4805c7c91f2384c2e36ff12c5f7 153 SUPERFAMILY SSF55961 10 149 7.54E-38 T 12-10-2018 AFR_24695 4e1bf4805c7c91f2384c2e36ff12c5f7 153 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 21 149 3.2E-23 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_00085 4c38a670256082fc01e26326909c4e22 183 Pfam PF04073 Aminoacyl-tRNA editing domain 47 165 6.3E-20 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFR_00085 4c38a670256082fc01e26326909c4e22 183 SUPERFAMILY SSF55826 32 176 3.27E-25 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_00085 4c38a670256082fc01e26326909c4e22 183 Gene3D G3DSA:3.90.960.10 38 177 1.0E-25 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_22475 2cd654c607b2ddb32fd5ce3aa84d29ff 652 Pfam PF13646 HEAT repeats 118 197 7.6E-7 T 12-10-2018 AFR_22475 2cd654c607b2ddb32fd5ce3aa84d29ff 652 Pfam PF00534 Glycosyl transferases group 1 452 607 9.7E-19 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_22475 2cd654c607b2ddb32fd5ce3aa84d29ff 652 SUPERFAMILY SSF53756 240 645 7.85E-45 T 12-10-2018 AFR_22475 2cd654c607b2ddb32fd5ce3aa84d29ff 652 SUPERFAMILY SSF48371 28 194 7.14E-8 T 12-10-2018 IPR016024 Armadillo-type fold AFR_22475 2cd654c607b2ddb32fd5ce3aa84d29ff 652 Gene3D G3DSA:3.40.50.2000 444 625 5.2E-26 T 12-10-2018 AFR_22475 2cd654c607b2ddb32fd5ce3aa84d29ff 652 Gene3D G3DSA:3.40.50.2000 219 443 1.8E-18 T 12-10-2018 AFR_22475 2cd654c607b2ddb32fd5ce3aa84d29ff 652 Pfam PF13439 Glycosyltransferase Family 4 243 432 3.0E-11 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_14570 5df7cd6b435b6eed498398c22b5256fb 209 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 207 19.558 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 AFR_14570 5df7cd6b435b6eed498398c22b5256fb 209 Pfam PF02525 Flavodoxin-like fold 1 164 1.0E-20 T 12-10-2018 IPR003680 Flavodoxin-like fold AFR_14570 5df7cd6b435b6eed498398c22b5256fb 209 Gene3D G3DSA:3.40.50.360 1 203 4.3E-31 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_14570 5df7cd6b435b6eed498398c22b5256fb 209 SUPERFAMILY SSF52218 1 186 6.29E-28 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_35125 be25b0407584d7869bb70a219a877d13 134 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 11 131 5.8E-40 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFR_35125 be25b0407584d7869bb70a219a877d13 134 Pfam PF01641 SelR domain 14 132 2.2E-47 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFR_35125 be25b0407584d7869bb70a219a877d13 134 Gene3D G3DSA:2.170.150.20 1 134 5.8E-51 T 12-10-2018 AFR_35125 be25b0407584d7869bb70a219a877d13 134 SUPERFAMILY SSF51316 10 133 2.88E-50 T 12-10-2018 IPR011057 Mss4-like superfamily AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 261 275 3.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 291 303 3.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 275 291 3.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 Pfam PF13191 AAA ATPase domain 5 153 3.4E-15 T 12-10-2018 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 SUPERFAMILY SSF52540 5 240 3.98E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 Gene3D G3DSA:3.40.50.300 1 171 2.4E-6 T 12-10-2018 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 Gene3D G3DSA:1.10.10.10 247 320 4.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 SMART SM00421 258 315 9.9E-27 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 ProSitePatterns PS00622 LuxR-type HTH domain signature. 275 302 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 Pfam PF00196 Bacterial regulatory proteins, luxR family 261 315 7.0E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27150 9fbcbf99b0c9aef93f55cf8158324898 326 SUPERFAMILY SSF46894 252 320 6.8E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_05175 37b7576ec2365bde2acf0d2b58aac43d 332 Gene3D G3DSA:3.20.20.80 55 323 5.9E-50 T 12-10-2018 AFR_05175 37b7576ec2365bde2acf0d2b58aac43d 332 SUPERFAMILY SSF51445 77 302 1.3E-32 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_05175 37b7576ec2365bde2acf0d2b58aac43d 332 Pfam PF02156 Glycosyl hydrolase family 26 124 236 1.0E-5 T 12-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 AFR_11770 1b411dd942771fbfabe4c6302e19b3e4 228 SMART SM00014 89 202 3.6E-22 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_11770 1b411dd942771fbfabe4c6302e19b3e4 228 Pfam PF01569 PAP2 superfamily 90 207 3.7E-21 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_11770 1b411dd942771fbfabe4c6302e19b3e4 228 SUPERFAMILY SSF48317 10 212 4.84E-37 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_11770 1b411dd942771fbfabe4c6302e19b3e4 228 Gene3D G3DSA:1.20.144.10 3 120 1.3E-5 T 12-10-2018 AFR_11770 1b411dd942771fbfabe4c6302e19b3e4 228 Gene3D G3DSA:1.20.144.10 121 219 4.4E-23 T 12-10-2018 AFR_04045 b5e3532ac35a1fd7a9ec455f562e6ab3 200 Pfam PF13649 Methyltransferase domain 46 136 1.2E-15 T 12-10-2018 AFR_04045 b5e3532ac35a1fd7a9ec455f562e6ab3 200 Gene3D G3DSA:3.40.50.150 3 199 1.3E-49 T 12-10-2018 AFR_04045 b5e3532ac35a1fd7a9ec455f562e6ab3 200 SUPERFAMILY SSF53335 4 186 2.99E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 SUPERFAMILY SSF54211 479 603 2.5E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Gene3D G3DSA:3.30.70.240 608 678 1.0E-84 T 12-10-2018 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 SUPERFAMILY SSF54980 607 693 7.67E-30 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Pfam PF00679 Elongation factor G C-terminus 605 690 9.3E-30 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 170 4.6E-34 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 SUPERFAMILY SSF54980 404 481 4.32E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Gene3D G3DSA:2.40.30.10 294 405 2.2E-43 T 12-10-2018 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Hamap MF_00054_B Elongation factor G [fusA]. 6 695 111.109 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Pfam PF00009 Elongation factor Tu GTP binding domain 9 282 1.8E-67 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 SUPERFAMILY SSF52540 8 282 4.58E-107 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Pfam PF14492 Elongation Factor G, domain II 404 478 4.4E-34 T 12-10-2018 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 SMART SM00889 480 602 1.2E-67 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Gene3D G3DSA:3.40.50.300 3 293 2.1E-114 T 12-10-2018 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 TIGRFAM TIGR00484 EF-G: translation elongation factor G 6 695 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Pfam PF03764 Elongation factor G, domain IV 479 601 9.3E-45 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Gene3D G3DSA:3.30.230.10 484 691 1.0E-84 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Pfam PF03144 Elongation factor Tu domain 2 324 390 7.1E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 SUPERFAMILY SSF50447 265 404 1.04E-36 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 SMART SM00838 604 691 9.7E-57 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.1E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.1E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.1E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.1E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.1E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04490 99caf45cbaccd7e656e827ee9b86c61e 698 Gene3D G3DSA:3.30.70.870 406 480 3.0E-32 T 12-10-2018 AFR_27780 249ca777d830cc5680096dfd7917e855 478 Pfam PF00171 Aldehyde dehydrogenase family 24 472 9.5E-157 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_27780 249ca777d830cc5680096dfd7917e855 478 Gene3D G3DSA:3.40.605.10 26 466 5.4E-164 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_27780 249ca777d830cc5680096dfd7917e855 478 SUPERFAMILY SSF53720 6 474 4.97E-155 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_27780 249ca777d830cc5680096dfd7917e855 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_27780 249ca777d830cc5680096dfd7917e855 478 Gene3D G3DSA:3.40.309.10 253 441 5.4E-164 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_27780 249ca777d830cc5680096dfd7917e855 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_34215 1e227e91b89f501aef6d346137d97485 219 SUPERFAMILY SSF52172 4 138 1.57E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_34215 1e227e91b89f501aef6d346137d97485 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.5E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34215 1e227e91b89f501aef6d346137d97485 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.5E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34215 1e227e91b89f501aef6d346137d97485 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.5E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34215 1e227e91b89f501aef6d346137d97485 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34215 1e227e91b89f501aef6d346137d97485 219 SUPERFAMILY SSF46894 152 218 5.1E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_34215 1e227e91b89f501aef6d346137d97485 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.1E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34215 1e227e91b89f501aef6d346137d97485 219 Gene3D G3DSA:3.40.50.12740 5 218 2.6E-68 T 12-10-2018 AFR_34215 1e227e91b89f501aef6d346137d97485 219 Pfam PF00072 Response regulator receiver domain 7 119 5.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34215 1e227e91b89f501aef6d346137d97485 219 SMART SM00421 155 212 4.3E-29 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34215 1e227e91b89f501aef6d346137d97485 219 SMART SM00448 5 120 5.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 Pfam PF00285 Citrate synthase, C-terminal domain 63 382 6.2E-62 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 PRINTS PR00143 Citrate synthase signature 228 256 1.3E-20 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 PRINTS PR00143 Citrate synthase signature 281 301 1.3E-20 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 PRINTS PR00143 Citrate synthase signature 352 366 1.3E-20 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 PRINTS PR00143 Citrate synthase signature 206 221 1.3E-20 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 Gene3D G3DSA:1.10.230.10 254 346 1.0E-60 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFR_16670 9dce071bc9489c078a82a48c0b900853 393 SUPERFAMILY SSF48256 66 391 5.76E-66 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 SUPERFAMILY SSF46955 5 57 9.16E-8 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_16670 9dce071bc9489c078a82a48c0b900853 393 Gene3D G3DSA:1.10.580.10 78 372 1.0E-60 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 Pfam PF12728 Helix-turn-helix domain 6 57 8.6E-8 T 12-10-2018 AFR_16670 9dce071bc9489c078a82a48c0b900853 393 Gene3D G3DSA:1.10.1660.10 5 66 6.0E-7 T 12-10-2018 AFR_21430 5f5d6aba73211d2887adc1603e0e6a97 232 Gene3D G3DSA:3.10.180.10 115 229 2.7E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21430 5f5d6aba73211d2887adc1603e0e6a97 232 Gene3D G3DSA:3.10.180.10 3 114 1.7E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21430 5f5d6aba73211d2887adc1603e0e6a97 232 SUPERFAMILY SSF54593 134 227 1.45E-7 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21430 5f5d6aba73211d2887adc1603e0e6a97 232 SUPERFAMILY SSF54593 15 112 4.3E-8 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_12655 3d28433b493006507e78beb2a463d5d3 153 SUPERFAMILY SSF54593 3 145 3.52E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_12655 3d28433b493006507e78beb2a463d5d3 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 144 3.2E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_12655 3d28433b493006507e78beb2a463d5d3 153 Gene3D G3DSA:3.10.180.10 9 152 1.2E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 Gene3D G3DSA:3.30.70.2010 2 106 6.2E-29 T 12-10-2018 AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 Gene3D G3DSA:3.30.60.70 107 147 1.0E-12 T 12-10-2018 IPR038361 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain superfamily KEGG: 00300+2.3.1.117 AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 10 314 8.5E-138 T 12-10-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 SUPERFAMILY SSF51161 75 293 5.41E-36 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 229 261 2.1E-15 T 12-10-2018 IPR001451 Hexapeptide repeat AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 Gene3D G3DSA:2.160.10.10 148 315 4.8E-67 T 12-10-2018 AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 7 312 42.477 T 12-10-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 AFR_38530 864f74510e4ac5d8941a6c58a8d36cee 315 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 107 147 8.0E-16 T 12-10-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 AFR_00645 ee03acab0c5e7dc9072b2466ecb5d4f3 252 Gene3D G3DSA:3.30.470.30 12 160 2.9E-7 T 12-10-2018 AFR_00645 ee03acab0c5e7dc9072b2466ecb5d4f3 252 Pfam PF09414 RNA ligase 38 237 2.8E-14 T 12-10-2018 IPR021122 RNA ligase domain, REL/Rln2 AFR_00645 ee03acab0c5e7dc9072b2466ecb5d4f3 252 SUPERFAMILY SSF56091 11 158 3.6E-14 T 12-10-2018 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 Pfam PF13416 Bacterial extracellular solute-binding protein 63 357 2.5E-42 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 Gene3D G3DSA:3.40.190.10 57 380 1.7E-102 T 12-10-2018 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 Gene3D G3DSA:3.40.190.10 153 412 1.7E-102 T 12-10-2018 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 PRINTS PR00181 Maltose binding protein signature 380 399 8.3E-9 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 PRINTS PR00181 Maltose binding protein signature 322 343 8.3E-9 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 PRINTS PR00181 Maltose binding protein signature 84 102 8.3E-9 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 PRINTS PR00181 Maltose binding protein signature 165 184 8.3E-9 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 PRINTS PR00181 Maltose binding protein signature 144 163 8.3E-9 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFR_19390 3dd4e4d0bc10506aca25277ea1996c8b 422 SUPERFAMILY SSF53850 42 416 1.19E-71 T 12-10-2018 AFR_15320 a15ba95e67c5b08fafe560fba078cd97 374 ProSitePatterns PS01125 ROK family signature. 187 214 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_15320 a15ba95e67c5b08fafe560fba078cd97 374 SUPERFAMILY SSF46785 2 53 5.34E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15320 a15ba95e67c5b08fafe560fba078cd97 374 Gene3D G3DSA:1.10.10.10 1 60 2.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15320 a15ba95e67c5b08fafe560fba078cd97 374 Gene3D G3DSA:3.30.420.40 71 357 6.3E-60 T 12-10-2018 AFR_15320 a15ba95e67c5b08fafe560fba078cd97 374 Pfam PF00480 ROK family 66 362 4.7E-37 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_15320 a15ba95e67c5b08fafe560fba078cd97 374 SUPERFAMILY SSF53067 66 363 6.98E-41 T 12-10-2018 AFR_15320 a15ba95e67c5b08fafe560fba078cd97 374 Gene3D G3DSA:3.30.420.40 177 347 6.3E-60 T 12-10-2018 AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 Hamap MF_01987 Ribokinase [rbsK]. 4 294 25.229 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 239 252 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 Gene3D G3DSA:3.40.1190.20 1 297 4.2E-89 T 12-10-2018 IPR029056 Ribokinase-like AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 SUPERFAMILY SSF53613 1 290 3.9E-70 T 12-10-2018 IPR029056 Ribokinase-like AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 Pfam PF00294 pfkB family carbohydrate kinase 5 287 1.5E-60 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 PRINTS PR00990 Ribokinase signature 35 54 4.2E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 PRINTS PR00990 Ribokinase signature 173 188 4.2E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 PRINTS PR00990 Ribokinase signature 209 220 4.2E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 PRINTS PR00990 Ribokinase signature 8 29 4.2E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_37085 c7c737316621a3e009daf24ce6d05e64 301 PRINTS PR00990 Ribokinase signature 106 119 4.2E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_38010 4aa97da48e161d116627c1d053c40428 303 Pfam PF12740 Chlorophyllase enzyme 76 205 5.4E-12 T 12-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 AFR_38010 4aa97da48e161d116627c1d053c40428 303 Gene3D G3DSA:3.40.50.1820 44 299 1.2E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_38010 4aa97da48e161d116627c1d053c40428 303 SUPERFAMILY SSF53474 55 293 2.11E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16370 6e3e9c806b11ee71576d055a5ab63a20 293 Gene3D G3DSA:1.10.357.140 23 169 1.3E-8 T 12-10-2018 AFR_16370 6e3e9c806b11ee71576d055a5ab63a20 293 Pfam PF01040 UbiA prenyltransferase family 29 261 4.1E-25 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFR_14750 fea55b02d50032058c0f5a2cf3d0b83f 206 Pfam PF01872 RibD C-terminal domain 5 198 7.2E-19 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_14750 fea55b02d50032058c0f5a2cf3d0b83f 206 SUPERFAMILY SSF53597 5 190 7.46E-24 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_14750 fea55b02d50032058c0f5a2cf3d0b83f 206 Gene3D G3DSA:3.40.430.10 2 203 2.7E-49 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 Gene3D G3DSA:3.30.360.10 151 314 5.3E-134 T 12-10-2018 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.3E-33 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 2.3E-33 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 2.3E-33 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 2.3E-33 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 2.3E-33 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 SUPERFAMILY SSF51735 3 166 4.54E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 PIRSF PIRSF000149 1 331 2.1E-119 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 Gene3D G3DSA:3.40.50.720 3 325 5.3E-134 T 12-10-2018 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 3.7E-120 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 SMART SM00846 2 152 6.5E-81 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 SUPERFAMILY SSF55347 152 313 2.35E-62 T 12-10-2018 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 312 1.9E-58 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_34140 ef9db9f97af66c1d601cd251b73f3d57 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.7E-34 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_39375 d9af2fa5a4cd1a2e028bea077c452249 316 Pfam PF13732 Domain of unknown function (DUF4162) 222 309 1.3E-10 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 AFR_39375 d9af2fa5a4cd1a2e028bea077c452249 316 SMART SM00382 34 217 1.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_39375 d9af2fa5a4cd1a2e028bea077c452249 316 SUPERFAMILY SSF52540 2 229 1.69E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39375 d9af2fa5a4cd1a2e028bea077c452249 316 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_39375 d9af2fa5a4cd1a2e028bea077c452249 316 Pfam PF00005 ABC transporter 26 168 3.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_39375 d9af2fa5a4cd1a2e028bea077c452249 316 Gene3D G3DSA:3.40.50.300 1 238 6.0E-71 T 12-10-2018 AFR_39375 d9af2fa5a4cd1a2e028bea077c452249 316 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 22 310 2.3E-104 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFR_27475 ef88bff1be546508c4904b79fd453165 250 Pfam PF08445 FR47-like protein 182 244 1.2E-8 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_27475 ef88bff1be546508c4904b79fd453165 250 Gene3D G3DSA:3.40.630.30 1 248 4.5E-56 T 12-10-2018 AFR_27475 ef88bff1be546508c4904b79fd453165 250 SUPERFAMILY SSF55729 55 244 9.04E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_01225 9d678bc31bdacd0e76d4ce8eda1576c7 338 SMART SM00331 160 337 4.1E-7 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01225 9d678bc31bdacd0e76d4ce8eda1576c7 338 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 172 337 3.0E-14 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01225 9d678bc31bdacd0e76d4ce8eda1576c7 338 Gene3D G3DSA:3.30.565.10 16 142 1.3E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01225 9d678bc31bdacd0e76d4ce8eda1576c7 338 Gene3D G3DSA:3.60.40.10 149 336 1.8E-40 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01225 9d678bc31bdacd0e76d4ce8eda1576c7 338 Pfam PF13581 Histidine kinase-like ATPase domain 22 115 2.0E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01225 9d678bc31bdacd0e76d4ce8eda1576c7 338 SUPERFAMILY SSF81606 160 336 1.57E-10 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01225 9d678bc31bdacd0e76d4ce8eda1576c7 338 SUPERFAMILY SSF55874 37 137 5.87E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_35255 012b9113223905d9968265a6b3713c33 450 Pfam PF00375 Sodium:dicarboxylate symporter family 18 407 9.8E-99 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFR_35255 012b9113223905d9968265a6b3713c33 450 Gene3D G3DSA:1.10.3860.10 9 424 8.0E-110 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 AFR_35255 012b9113223905d9968265a6b3713c33 450 SUPERFAMILY SSF118215 18 408 7.06E-102 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 AFR_35255 012b9113223905d9968265a6b3713c33 450 PRINTS PR00173 Glutamate-aspartate symporter signature 16 36 9.7E-27 T 12-10-2018 AFR_35255 012b9113223905d9968265a6b3713c33 450 PRINTS PR00173 Glutamate-aspartate symporter signature 198 217 9.7E-27 T 12-10-2018 AFR_35255 012b9113223905d9968265a6b3713c33 450 PRINTS PR00173 Glutamate-aspartate symporter signature 334 353 9.7E-27 T 12-10-2018 AFR_35255 012b9113223905d9968265a6b3713c33 450 PRINTS PR00173 Glutamate-aspartate symporter signature 299 325 9.7E-27 T 12-10-2018 AFR_35255 012b9113223905d9968265a6b3713c33 450 PRINTS PR00173 Glutamate-aspartate symporter signature 225 244 9.7E-27 T 12-10-2018 AFR_35255 012b9113223905d9968265a6b3713c33 450 PRINTS PR00173 Glutamate-aspartate symporter signature 83 108 9.7E-27 T 12-10-2018 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 SUPERFAMILY SSF52374 1 278 8.0E-82 T 12-10-2018 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 Gene3D G3DSA:1.10.10.350 355 453 3.9E-25 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 449 25.549 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 Gene3D G3DSA:3.40.50.620 1 293 1.7E-97 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_08735 25c773305b2eca00a176ea485988ca2e 453 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 1 446 3.8E-112 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 PRINTS PR00987 Glutamyl-tRNA synthetase signature 158 168 3.3E-12 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 PRINTS PR00987 Glutamyl-tRNA synthetase signature 4 15 3.3E-12 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 PRINTS PR00987 Glutamyl-tRNA synthetase signature 174 182 3.3E-12 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 32 3.3E-12 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 SUPERFAMILY SSF48163 279 448 1.05E-35 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFR_08735 25c773305b2eca00a176ea485988ca2e 453 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 1 284 1.3E-65 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 Pfam PF00294 pfkB family carbohydrate kinase 27 261 1.1E-16 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 PIRSF PIRSF000535 185 283 0.0035 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 PIRSF PIRSF000535 1 194 5.5E-29 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 PRINTS PR00990 Ribokinase signature 194 205 1.3E-6 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 PRINTS PR00990 Ribokinase signature 33 52 1.3E-6 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 PRINTS PR00990 Ribokinase signature 169 184 1.3E-6 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 SUPERFAMILY SSF53613 6 272 1.08E-35 T 12-10-2018 IPR029056 Ribokinase-like AFR_33850 3a8a13692e9b74664cb0b19e6c938d2d 285 Gene3D G3DSA:3.40.1190.20 2 285 1.8E-55 T 12-10-2018 IPR029056 Ribokinase-like AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 SUPERFAMILY SSF46548 119 231 1.62E-22 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 Gene3D G3DSA:1.10.1060.10 133 243 3.3E-13 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 Gene3D G3DSA:3.10.20.30 1 116 6.1E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 120 1.1E-24 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 Pfam PF13183 4Fe-4S dicluster domain 156 228 6.1E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 SUPERFAMILY SSF54292 2 116 1.91E-21 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_09790 68c21dcfa99bc494d3c21b1dfe9af435 247 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 159 170 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_10395 da719af24119be1872b4d0c15465e6d8 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 15 299 1.0E-43 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 Pfam PF00245 Alkaline phosphatase 37 396 7.6E-103 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 Pfam PF00245 Alkaline phosphatase 400 438 1.5E-6 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 SMART SM00098 38 440 1.3E-141 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 ProSitePatterns PS00123 Alkaline phosphatase active site. 94 102 - T 12-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 Gene3D G3DSA:3.40.720.10 6 440 1.4E-128 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 PRINTS PR00113 Alkaline phosphatase signature 193 203 4.7E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 PRINTS PR00113 Alkaline phosphatase signature 131 151 4.7E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 PRINTS PR00113 Alkaline phosphatase signature 37 57 4.7E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 PRINTS PR00113 Alkaline phosphatase signature 290 319 4.7E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 PRINTS PR00113 Alkaline phosphatase signature 94 109 4.7E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AFR_33465 3c1d269b95b319b677d05ff9a14f1172 440 SUPERFAMILY SSF53649 24 439 4.03E-118 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_04175 75f1c3c825f17d8352a4a266b932809b 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 5.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04175 75f1c3c825f17d8352a4a266b932809b 227 SUPERFAMILY SSF48498 87 217 1.13E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_04175 75f1c3c825f17d8352a4a266b932809b 227 Gene3D G3DSA:1.10.357.10 1 226 5.7E-71 T 12-10-2018 AFR_04175 75f1c3c825f17d8352a4a266b932809b 227 SUPERFAMILY SSF46689 7 80 6.8E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00387 1156 1281 4.2E-38 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SUPERFAMILY SSF55781 791 964 5.4E-26 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1156 1279 7.6E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:3.30.565.10 1110 1281 3.4E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SUPERFAMILY SSF58104 220 537 2.38E-19 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:3.40.50.12740 1334 1465 4.3E-38 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SUPERFAMILY SSF58104 496 716 3.14E-15 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00448 1335 1449 9.3E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Pfam PF13185 GAF domain 826 963 1.1E-14 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SUPERFAMILY SSF55874 1098 1278 8.51E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00388 1041 1109 9.4E-22 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Pfam PF00072 Response regulator receiver domain 1337 1448 1.2E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:1.10.287.130 1027 1109 2.6E-23 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:1.10.8.500 666 718 7.1E-8 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:1.10.8.500 203 259 4.3E-8 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:1.10.8.500 754 813 6.6E-6 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:3.30.450.40 814 975 2.7E-20 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SUPERFAMILY SSF58104 136 258 4.97E-8 T 12-10-2018 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SUPERFAMILY SSF52172 1327 1454 2.7E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:2.60.120.260 472 563 4.2E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:2.60.120.260 380 471 2.3E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:2.60.120.260 286 379 2.9E-11 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Gene3D G3DSA:2.60.120.260 564 665 7.1E-11 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1042 1109 7.3E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 292 344 4.5E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 200 252 1.1E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 568 620 5.5E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 384 436 9.6E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 476 528 3.8E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 12 62 12.0 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 660 712 1.3E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 752 804 3.2E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00304 103 160 0.037 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SUPERFAMILY SSF47384 1028 1110 1.92E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1224 1234 4.6E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1265 1278 4.6E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1206 1220 4.6E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1241 1259 4.6E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01295 a7cc2a3762a601d839175999a7c674ba 1466 SMART SM00065 828 973 4.0E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31555 123febfd463196c3a82961d496280f5f 769 Pfam PF00563 EAL domain 511 745 5.7E-65 T 12-10-2018 IPR001633 EAL domain AFR_31555 123febfd463196c3a82961d496280f5f 769 SMART SM00267 320 492 3.4E-59 T 12-10-2018 IPR000160 GGDEF domain AFR_31555 123febfd463196c3a82961d496280f5f 769 Pfam PF00990 Diguanylate cyclase, GGDEF domain 331 487 8.4E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_31555 123febfd463196c3a82961d496280f5f 769 Gene3D G3DSA:3.20.20.450 505 759 9.0E-80 T 12-10-2018 IPR035919 EAL domain superfamily AFR_31555 123febfd463196c3a82961d496280f5f 769 SUPERFAMILY SSF55073 336 493 1.73E-44 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_31555 123febfd463196c3a82961d496280f5f 769 Gene3D G3DSA:3.30.70.270 318 492 3.5E-54 T 12-10-2018 AFR_31555 123febfd463196c3a82961d496280f5f 769 SMART SM00052 500 750 2.1E-78 T 12-10-2018 IPR001633 EAL domain AFR_31555 123febfd463196c3a82961d496280f5f 769 SUPERFAMILY SSF141868 516 755 9.94E-69 T 12-10-2018 IPR035919 EAL domain superfamily AFR_31555 123febfd463196c3a82961d496280f5f 769 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 327 489 2.2E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 PIRSF PIRSF039102 4 365 1.4E-108 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 Gene3D G3DSA:3.40.50.20 5 135 2.7E-38 T 12-10-2018 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 302 330 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 SUPERFAMILY SSF52440 6 146 3.07E-35 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 114 125 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 Gene3D G3DSA:3.30.1490.20 162 228 1.1E-75 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 Pfam PF01820 D-ala D-ala ligase N-terminus 8 136 3.4E-30 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 Pfam PF07478 D-ala D-ala ligase C-terminus 155 356 2.7E-67 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 Gene3D G3DSA:3.30.470.20 136 362 1.1E-75 T 12-10-2018 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 SUPERFAMILY SSF56059 147 361 4.24E-57 T 12-10-2018 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 8 359 8.3E-107 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_36615 b533000dc71af8041eaec5fbbc875d0f 367 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 7 360 40.855 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 Gene3D G3DSA:3.40.190.10 162 254 1.6E-34 T 12-10-2018 AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 SUPERFAMILY SSF46785 4 108 1.36E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 Pfam PF03466 LysR substrate binding domain 91 280 2.2E-20 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 2.0E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 SUPERFAMILY SSF53850 92 283 5.07E-20 T 12-10-2018 AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 Gene3D G3DSA:1.10.10.10 4 92 2.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 Gene3D G3DSA:3.40.190.10 96 258 1.6E-34 T 12-10-2018 AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_22235 8c470a3b4409961dbc0d8cb1096d22b7 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23945 511fc267e1f785ad9c2b1620c06084bf 293 Pfam PF13460 NAD(P)H-binding 8 192 1.5E-22 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_23945 511fc267e1f785ad9c2b1620c06084bf 293 Gene3D G3DSA:3.40.50.720 4 202 1.7E-62 T 12-10-2018 AFR_23945 511fc267e1f785ad9c2b1620c06084bf 293 Gene3D G3DSA:3.90.25.10 144 265 1.7E-62 T 12-10-2018 AFR_23945 511fc267e1f785ad9c2b1620c06084bf 293 SUPERFAMILY SSF51735 4 251 1.04E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23845 a0a6bb45b19a25443fa4e5306d0445f6 116 Gene3D G3DSA:1.20.890.50 82 116 4.1E-15 T 12-10-2018 AFR_23845 a0a6bb45b19a25443fa4e5306d0445f6 116 Pfam PF11774 Lsr2 1 113 5.0E-39 T 12-10-2018 IPR024412 Lsr2 AFR_23845 a0a6bb45b19a25443fa4e5306d0445f6 116 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 113 2.0E-19 T 12-10-2018 IPR024412 Lsr2 AFR_23845 a0a6bb45b19a25443fa4e5306d0445f6 116 Gene3D G3DSA:3.30.60.230 1 59 2.0E-22 T 12-10-2018 AFR_41360 86b033abc70ad164ed170c20f0ccdb00 117 Gene3D G3DSA:1.20.890.50 80 115 1.2E-14 T 12-10-2018 AFR_41360 86b033abc70ad164ed170c20f0ccdb00 117 Pfam PF11774 Lsr2 2 112 1.4E-37 T 12-10-2018 IPR024412 Lsr2 AFR_41360 86b033abc70ad164ed170c20f0ccdb00 117 Gene3D G3DSA:3.30.60.230 1 59 4.7E-23 T 12-10-2018 AFR_41360 86b033abc70ad164ed170c20f0ccdb00 117 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 112 8.0E-22 T 12-10-2018 IPR024412 Lsr2 AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 SUPERFAMILY SSF48498 82 205 2.45E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.4E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 Gene3D G3DSA:1.10.10.60 2 57 9.3E-18 T 12-10-2018 AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 SUPERFAMILY SSF46689 6 87 2.77E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 Gene3D G3DSA:1.10.357.10 58 206 7.6E-28 T 12-10-2018 AFR_12995 3018d0822d6fd508b2fd595b7b50f427 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 SUPERFAMILY SSF55136 114 261 2.44E-17 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 SMART SM00422 2 72 2.7E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 Gene3D G3DSA:1.10.1660.10 1 111 6.5E-22 T 12-10-2018 AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 Pfam PF06445 GyrI-like small molecule binding domain 114 260 3.8E-12 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 SMART SM00871 113 261 2.4E-14 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 SUPERFAMILY SSF46955 2 105 8.42E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 Gene3D G3DSA:3.20.80.10 112 261 3.0E-24 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_11350 c6e37bffe96417ee47c3a3636fe735cd 264 Pfam PF13411 MerR HTH family regulatory protein 3 71 1.5E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 SUPERFAMILY SSF158472 111 159 3.14E-8 T 12-10-2018 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 Gene3D G3DSA:3.30.565.10 230 386 6.8E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 163 229 2.5E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 341 1.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 365 1.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 384 1.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 SMART SM00387 276 387 1.8E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 SMART SM00388 163 230 2.0E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 Pfam PF00672 HAMP domain 110 158 5.6E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 SMART SM00304 109 162 1.4E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 SUPERFAMILY SSF47384 146 229 1.24E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 Gene3D G3DSA:1.10.287.130 113 229 5.3E-28 T 12-10-2018 AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 SUPERFAMILY SSF55874 224 385 3.8E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_35225 84e96149e919a3ef628cf627b2bd53a5 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 276 385 9.8E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_20740 5a463c95eab4a81aebc24dd64de448af 257 Gene3D G3DSA:3.20.20.150 1 249 2.9E-49 T 12-10-2018 AFR_20740 5a463c95eab4a81aebc24dd64de448af 257 SUPERFAMILY SSF51658 2 247 6.22E-51 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_20740 5a463c95eab4a81aebc24dd64de448af 257 Pfam PF01261 Xylose isomerase-like TIM barrel 38 211 1.2E-17 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_20740 5a463c95eab4a81aebc24dd64de448af 257 PIRSF PIRSF006241 1 250 4.1E-52 T 12-10-2018 IPR026040 Hydroxypyruvate isomerase-like AFR_01600 0c76ec8611ed8d21f178a1d64eb2a601 315 SUPERFAMILY SSF51430 1 313 2.88E-98 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_01600 0c76ec8611ed8d21f178a1d64eb2a601 315 Pfam PF00248 Aldo/keto reductase family 16 313 2.8E-68 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_01600 0c76ec8611ed8d21f178a1d64eb2a601 315 Gene3D G3DSA:3.20.20.100 1 314 1.1E-112 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 SMART SM00267 357 528 4.3E-61 T 12-10-2018 IPR000160 GGDEF domain AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 Gene3D G3DSA:3.30.70.270 362 528 9.5E-58 T 12-10-2018 AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 SUPERFAMILY SSF55781 208 359 1.0E-13 T 12-10-2018 AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 Gene3D G3DSA:3.30.450.40 180 361 5.9E-13 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 364 522 4.2E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 Pfam PF00990 Diguanylate cyclase, GGDEF domain 368 523 7.5E-48 T 12-10-2018 IPR000160 GGDEF domain AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 SMART SM00065 207 358 5.9E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 SUPERFAMILY SSF55073 373 524 1.33E-48 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_27350 96d8093bd766ecf447fad8da9e58f1b1 530 Pfam PF13185 GAF domain 206 348 5.3E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 Gene3D G3DSA:2.80.10.50 396 521 1.0E-39 T 12-10-2018 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 Pfam PF16499 Alpha galactosidase A 34 301 1.4E-77 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 SMART SM00458 396 523 6.9E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17105 7163dfad7200a9c94915f239b583aa56 523 SUPERFAMILY SSF51011 303 389 2.16E-20 T 12-10-2018 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 ProSitePatterns PS00512 Alpha-galactosidase signature. 72 88 - T 12-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 SUPERFAMILY SSF50370 398 520 4.19E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_17105 7163dfad7200a9c94915f239b583aa56 523 Gene3D G3DSA:2.60.40.1180 304 389 1.1E-21 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_17105 7163dfad7200a9c94915f239b583aa56 523 Gene3D G3DSA:3.20.20.70 27 303 3.0E-126 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 SUPERFAMILY SSF51445 26 302 4.56E-99 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_17105 7163dfad7200a9c94915f239b583aa56 523 Pfam PF00652 Ricin-type beta-trefoil lectin domain 399 520 3.0E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17105 7163dfad7200a9c94915f239b583aa56 523 PRINTS PR00740 Glycosyl hydrolase family 27 signature 144 161 2.9E-59 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 PRINTS PR00740 Glycosyl hydrolase family 27 signature 257 278 2.9E-59 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 PRINTS PR00740 Glycosyl hydrolase family 27 signature 236 255 2.9E-59 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 PRINTS PR00740 Glycosyl hydrolase family 27 signature 108 129 2.9E-59 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 PRINTS PR00740 Glycosyl hydrolase family 27 signature 29 48 2.9E-59 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 PRINTS PR00740 Glycosyl hydrolase family 27 signature 67 82 2.9E-59 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_17105 7163dfad7200a9c94915f239b583aa56 523 PRINTS PR00740 Glycosyl hydrolase family 27 signature 171 189 2.9E-59 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_41540 b55c665ada437683d293af1c43c46a71 677 Pfam PF01434 Peptidase family M41 405 610 6.2E-79 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFR_41540 b55c665ada437683d293af1c43c46a71 677 Gene3D G3DSA:3.40.50.300 159 341 2.5E-67 T 12-10-2018 AFR_41540 b55c665ada437683d293af1c43c46a71 677 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 643 36.722 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFR_41540 b55c665ada437683d293af1c43c46a71 677 SMART SM00382 204 343 2.2E-23 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41540 b55c665ada437683d293af1c43c46a71 677 Gene3D G3DSA:1.10.8.60 342 419 1.9E-27 T 12-10-2018 AFR_41540 b55c665ada437683d293af1c43c46a71 677 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 340 2.4E-43 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_41540 b55c665ada437683d293af1c43c46a71 677 SUPERFAMILY SSF140990 423 619 4.84E-70 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFR_41540 b55c665ada437683d293af1c43c46a71 677 SUPERFAMILY SSF52540 161 411 3.13E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41540 b55c665ada437683d293af1c43c46a71 677 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 121 611 1.1E-230 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFR_41540 b55c665ada437683d293af1c43c46a71 677 ProSitePatterns PS00674 AAA-protein family signature. 311 329 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFR_41540 b55c665ada437683d293af1c43c46a71 677 Gene3D G3DSA:1.20.58.760 422 620 2.4E-70 T 12-10-2018 AFR_13290 5412e09c8a9541057b2db9e0a9f4a110 232 Gene3D G3DSA:1.10.357.10 2 184 3.4E-32 T 12-10-2018 AFR_13290 5412e09c8a9541057b2db9e0a9f4a110 232 SUPERFAMILY SSF48498 80 168 3.81E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13290 5412e09c8a9541057b2db9e0a9f4a110 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.2E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13290 5412e09c8a9541057b2db9e0a9f4a110 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13290 5412e09c8a9541057b2db9e0a9f4a110 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13290 5412e09c8a9541057b2db9e0a9f4a110 232 SUPERFAMILY SSF46689 5 67 2.64E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 3.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 3.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 3.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 3.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 Gene3D G3DSA:1.10.10.10 12 146 2.5E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 SMART SM00347 31 131 9.1E-26 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 Pfam PF01047 MarR family 38 96 6.8E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02135 5cc37c8d8e8c8c18e6551df28acfa462 147 SUPERFAMILY SSF46785 11 143 1.53E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Gene3D G3DSA:2.60.40.10 499 578 1.4E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SMART SM00645 99 312 8.1E-5 T 12-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Gene3D G3DSA:2.60.40.10 414 498 3.5E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Pfam PF00112 Papain family cysteine protease 99 297 1.0E-9 T 12-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SUPERFAMILY SSF81296 666 746 6.38E-8 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SUPERFAMILY SSF54001 91 302 1.09E-27 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SUPERFAMILY SSF81296 499 577 1.87E-9 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SUPERFAMILY SSF81296 584 662 6.02E-12 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Gene3D G3DSA:2.60.40.10 581 665 2.6E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Gene3D G3DSA:2.60.40.10 666 749 8.8E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Gene3D G3DSA:2.60.40.10 326 413 2.1E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Pfam PF01833 IPT/TIG domain 416 488 3.7E-12 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Pfam PF01833 IPT/TIG domain 328 411 1.3E-9 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Pfam PF01833 IPT/TIG domain 500 577 6.0E-5 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Pfam PF01833 IPT/TIG domain 584 662 5.2E-13 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Pfam PF01833 IPT/TIG domain 668 746 2.3E-6 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 Gene3D G3DSA:3.90.70.10 78 317 2.7E-39 T 12-10-2018 AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SUPERFAMILY SSF81296 327 411 2.45E-12 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SUPERFAMILY SSF81296 415 492 1.28E-10 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SMART SM00429 583 663 8.8E-4 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SMART SM00429 499 579 3.9 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SMART SM00429 415 495 8.3E-4 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SMART SM00429 327 412 0.84 T 12-10-2018 IPR002909 IPT domain AFR_31665 6caad3164772cb9003e594b73fa5684f 750 SMART SM00429 667 747 13.0 T 12-10-2018 IPR002909 IPT domain AFR_01695 0ea1e3fead5faf6656a85ec13595d2db 218 SUPERFAMILY SSF54862 27 142 1.51E-25 T 12-10-2018 AFR_01695 0ea1e3fead5faf6656a85ec13595d2db 218 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_01695 0ea1e3fead5faf6656a85ec13595d2db 218 Gene3D G3DSA:3.30.70.3270 27 184 8.9E-46 T 12-10-2018 AFR_01695 0ea1e3fead5faf6656a85ec13595d2db 218 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_01695 0ea1e3fead5faf6656a85ec13595d2db 218 Pfam PF12838 4Fe-4S dicluster domain 53 111 3.6E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_01695 0ea1e3fead5faf6656a85ec13595d2db 218 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 10 137 7.9E-41 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01695 0ea1e3fead5faf6656a85ec13595d2db 218 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 147 28.061 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_23625 24c7a7d40ca6af07ebd5500ee13dd97a 346 Gene3D G3DSA:1.10.3470.10 19 346 1.8E-81 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_23625 24c7a7d40ca6af07ebd5500ee13dd97a 346 SUPERFAMILY SSF81345 17 339 2.62E-66 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_23625 24c7a7d40ca6af07ebd5500ee13dd97a 346 Pfam PF01032 FecCD transport family 36 339 1.0E-73 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_31990 e23e1a8484408e94bf431bc26ef427b9 291 Pfam PF00248 Aldo/keto reductase family 12 289 7.7E-47 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_31990 e23e1a8484408e94bf431bc26ef427b9 291 Gene3D G3DSA:3.20.20.100 5 291 3.0E-62 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_31990 e23e1a8484408e94bf431bc26ef427b9 291 SUPERFAMILY SSF51430 7 289 1.44E-61 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_31990 e23e1a8484408e94bf431bc26ef427b9 291 PRINTS PR00069 Aldo-keto reductase signature 223 247 8.4E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_31990 e23e1a8484408e94bf431bc26ef427b9 291 PRINTS PR00069 Aldo-keto reductase signature 147 164 8.4E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_31990 e23e1a8484408e94bf431bc26ef427b9 291 PRINTS PR00069 Aldo-keto reductase signature 39 63 8.4E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_33685 b49ba1d1a27fc2607112a3585fdf1965 121 SUPERFAMILY SSF54593 8 119 5.81E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_33685 b49ba1d1a27fc2607112a3585fdf1965 121 Gene3D G3DSA:3.10.180.10 1 121 2.3E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_37355 af0480b8b5049066311f89183ec081a9 183 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 155 12.523 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFR_37355 af0480b8b5049066311f89183ec081a9 183 Pfam PF00430 ATP synthase B/B' CF(0) 24 153 3.0E-28 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFR_37355 af0480b8b5049066311f89183ec081a9 183 SUPERFAMILY SSF81573 80 138 1.96E-10 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily AFR_37355 af0480b8b5049066311f89183ec081a9 183 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 28 174 2.3E-29 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 AFR_22450 944deeb8d47b806b29fd717a2e6573c0 371 Pfam PF07721 Tetratricopeptide repeat 199 221 0.15 T 12-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 AFR_22450 944deeb8d47b806b29fd717a2e6573c0 371 Pfam PF07721 Tetratricopeptide repeat 138 157 0.027 T 12-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 AFR_22450 944deeb8d47b806b29fd717a2e6573c0 371 Pfam PF07721 Tetratricopeptide repeat 86 104 0.06 T 12-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 AFR_22450 944deeb8d47b806b29fd717a2e6573c0 371 Pfam PF07721 Tetratricopeptide repeat 339 359 0.008 T 12-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 AFR_22450 944deeb8d47b806b29fd717a2e6573c0 371 SUPERFAMILY SSF48452 85 359 2.2E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_22450 944deeb8d47b806b29fd717a2e6573c0 371 Gene3D G3DSA:1.25.40.10 3 361 2.3E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 PIRSF PIRSF000149 1 341 9.6E-80 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 318 3.6E-24 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 104 5.0E-30 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 Gene3D G3DSA:3.30.360.10 154 321 9.8E-99 T 12-10-2018 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 SMART SM00846 3 155 4.6E-60 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 SUPERFAMILY SSF55347 155 320 1.06E-30 T 12-10-2018 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 SUPERFAMILY SSF51735 4 171 5.37E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_08965 c4f4606d541540ab05f0b91f73701062 353 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 4.4E-11 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 275 290 4.4E-11 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 4.4E-11 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 235 252 4.4E-11 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_08965 c4f4606d541540ab05f0b91f73701062 353 Gene3D G3DSA:3.40.50.720 5 334 9.8E-99 T 12-10-2018 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Pfam PF03764 Elongation factor G, domain IV 500 617 4.3E-41 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 SMART SM00889 500 618 8.7E-60 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Pfam PF03144 Elongation factor Tu domain 2 335 411 6.5E-9 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Pfam PF00009 Elongation factor Tu GTP binding domain 20 292 4.1E-37 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 SUPERFAMILY SSF54211 500 617 1.11E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 SUPERFAMILY SSF54980 623 712 4.12E-20 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 22 158 3.9E-17 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 PRINTS PR00315 GTP-binding elongation factor signature 23 36 3.0E-6 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 PRINTS PR00315 GTP-binding elongation factor signature 105 116 3.0E-6 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 PRINTS PR00315 GTP-binding elongation factor signature 89 99 3.0E-6 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Gene3D G3DSA:3.40.50.300 13 297 9.3E-59 T 12-10-2018 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Gene3D G3DSA:3.30.70.240 624 696 3.0E-76 T 12-10-2018 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 SMART SM00838 620 709 4.1E-20 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Pfam PF00679 Elongation factor G C-terminus 621 707 2.4E-20 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Gene3D G3DSA:2.40.30.10 315 425 5.6E-28 T 12-10-2018 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 SUPERFAMILY SSF50447 260 422 2.2E-25 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 SUPERFAMILY SSF52540 17 293 4.18E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 SUPERFAMILY SSF54980 425 501 2.7E-15 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Pfam PF14492 Elongation Factor G, domain II 425 496 2.6E-21 T 12-10-2018 AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Gene3D G3DSA:3.30.230.10 504 708 3.0E-76 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_31120 119dc43ba1d093218b5fc4fa498431be 716 Gene3D G3DSA:3.30.70.870 426 498 8.1E-18 T 12-10-2018 AFR_31410 dd22f5539a85a2680024091875f646e7 204 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 65 5.3E-10 T 12-10-2018 IPR004176 Clp, N-terminal AFR_31410 dd22f5539a85a2680024091875f646e7 204 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 85 104 0.11 T 12-10-2018 IPR004176 Clp, N-terminal AFR_31410 dd22f5539a85a2680024091875f646e7 204 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 150 199 1.4E-13 T 12-10-2018 IPR004176 Clp, N-terminal AFR_31410 dd22f5539a85a2680024091875f646e7 204 Gene3D G3DSA:1.10.1780.10 1 79 1.5E-19 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_31410 dd22f5539a85a2680024091875f646e7 204 SUPERFAMILY SSF81923 137 201 2.22E-12 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_31410 dd22f5539a85a2680024091875f646e7 204 SUPERFAMILY SSF81923 3 104 1.18E-12 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_31410 dd22f5539a85a2680024091875f646e7 204 Gene3D G3DSA:1.10.1780.10 80 204 1.5E-30 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_36710 22fcff7b3a59100bfa17a97a7d7d92e5 267 SUPERFAMILY SSF51735 2 231 6.27E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36710 22fcff7b3a59100bfa17a97a7d7d92e5 267 Gene3D G3DSA:3.40.50.720 4 248 3.2E-56 T 12-10-2018 AFR_36710 22fcff7b3a59100bfa17a97a7d7d92e5 267 Pfam PF13460 NAD(P)H-binding 7 124 9.0E-13 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_36710 22fcff7b3a59100bfa17a97a7d7d92e5 267 Gene3D G3DSA:3.90.25.10 121 250 3.2E-56 T 12-10-2018 AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 SUPERFAMILY SSF90123 33 355 6.67E-75 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 Pfam PF00664 ABC transporter transmembrane region 47 321 1.0E-41 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 ProSitePatterns PS00211 ABC transporters family signature. 523 537 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 SMART SM00382 411 597 6.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 Gene3D G3DSA:3.40.50.300 357 624 1.2E-86 T 12-10-2018 AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 Gene3D G3DSA:1.20.1560.10 13 353 1.6E-81 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 SUPERFAMILY SSF52540 356 622 2.45E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10795 6d75e0b0a6c247ba5db83af6f88000a1 649 Pfam PF00005 ABC transporter 402 551 2.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01500 6a1b509e845c23c92a18a92d8aa40178 737 SUPERFAMILY SSF55831 434 570 2.36E-12 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_01500 6a1b509e845c23c92a18a92d8aa40178 737 SUPERFAMILY SSF56300 4 321 6.89E-28 T 12-10-2018 AFR_01500 6a1b509e845c23c92a18a92d8aa40178 737 Gene3D G3DSA:3.60.21.10 3 306 1.2E-20 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_01500 6a1b509e845c23c92a18a92d8aa40178 737 Pfam PF00149 Calcineurin-like phosphoesterase 4 288 5.3E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_01500 6a1b509e845c23c92a18a92d8aa40178 737 Gene3D G3DSA:3.30.572.10 434 574 4.7E-10 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_25325 b3561843d5c0c2e708bff9a8df5efe7f 309 SUPERFAMILY SSF56219 95 306 8.9E-23 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_25325 b3561843d5c0c2e708bff9a8df5efe7f 309 Gene3D G3DSA:3.60.10.10 93 308 1.9E-26 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_25325 b3561843d5c0c2e708bff9a8df5efe7f 309 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 108 298 7.3E-12 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_35570 023bfd9093964a312f1a276b0c3080c2 153 Pfam PF01152 Bacterial-like globin 6 103 4.2E-14 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 AFR_35570 023bfd9093964a312f1a276b0c3080c2 153 SUPERFAMILY SSF46458 3 116 9.05E-25 T 12-10-2018 IPR009050 Globin-like superfamily AFR_35570 023bfd9093964a312f1a276b0c3080c2 153 Gene3D G3DSA:1.10.490.10 1 128 2.0E-27 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 PIRSF PIRSF000124 1 416 2.1E-68 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 408 6.1E-20 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 Gene3D G3DSA:3.40.50.720 1 195 1.4E-63 T 12-10-2018 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 SUPERFAMILY SSF52413 305 410 1.15E-26 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 Gene3D G3DSA:3.40.50.720 197 417 8.6E-62 T 12-10-2018 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 PIRSF PIRSF500136 1 417 8.3E-146 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 178 1.3E-38 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 SUPERFAMILY SSF51735 1 192 1.38E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 SMART SM00984 317 412 1.6E-25 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 407 7.3E-124 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 SUPERFAMILY SSF48179 198 296 1.16E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_11625 d25a165fc0f5995aee2218a3cef20439 418 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 290 8.5E-26 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_17855 414d06193ec77811fd4dffde8628dab6 305 SUPERFAMILY SSF103481 45 143 3.92E-12 T 12-10-2018 AFR_17855 414d06193ec77811fd4dffde8628dab6 305 Pfam PF00892 EamA-like transporter family 10 140 5.7E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_17855 414d06193ec77811fd4dffde8628dab6 305 Pfam PF00892 EamA-like transporter family 152 286 2.3E-23 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_17855 414d06193ec77811fd4dffde8628dab6 305 SUPERFAMILY SSF103481 189 287 1.31E-15 T 12-10-2018 AFR_01675 0d4567b1c5427b1030947c9977769b6f 368 SUPERFAMILY SSF52833 17 178 1.12E-47 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_01675 0d4567b1c5427b1030947c9977769b6f 368 Gene3D G3DSA:3.40.30.10 87 191 2.2E-25 T 12-10-2018 AFR_01675 0d4567b1c5427b1030947c9977769b6f 368 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 25 168 1.2E-42 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01675 0d4567b1c5427b1030947c9977769b6f 368 Gene3D G3DSA:1.10.10.1590 16 86 6.0E-22 T 12-10-2018 AFR_01675 0d4567b1c5427b1030947c9977769b6f 368 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 25 169 6.8E-47 T 12-10-2018 AFR_25920 5d10b99bb93820444a0deb3293095a91 729 SUPERFAMILY SSF141868 480 722 1.83E-82 T 12-10-2018 IPR035919 EAL domain superfamily AFR_25920 5d10b99bb93820444a0deb3293095a91 729 Pfam PF00990 Diguanylate cyclase, GGDEF domain 310 459 6.0E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_25920 5d10b99bb93820444a0deb3293095a91 729 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 306 460 7.2E-31 T 12-10-2018 IPR000160 GGDEF domain AFR_25920 5d10b99bb93820444a0deb3293095a91 729 Gene3D G3DSA:3.30.70.270 295 463 2.9E-44 T 12-10-2018 AFR_25920 5d10b99bb93820444a0deb3293095a91 729 Gene3D G3DSA:3.20.20.450 475 726 1.7E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_25920 5d10b99bb93820444a0deb3293095a91 729 Pfam PF00563 EAL domain 480 715 4.8E-72 T 12-10-2018 IPR001633 EAL domain AFR_25920 5d10b99bb93820444a0deb3293095a91 729 SMART SM00052 473 720 1.5E-106 T 12-10-2018 IPR001633 EAL domain AFR_25920 5d10b99bb93820444a0deb3293095a91 729 SUPERFAMILY SSF55073 315 460 7.45E-39 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_25920 5d10b99bb93820444a0deb3293095a91 729 SMART SM00267 299 464 2.4E-44 T 12-10-2018 IPR000160 GGDEF domain AFR_08220 19219fe3337b4a6c5b21c3f8889284d1 394 SUPERFAMILY SSF51735 4 165 4.16E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_08220 19219fe3337b4a6c5b21c3f8889284d1 394 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 145 217 7.5E-10 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_08220 19219fe3337b4a6c5b21c3f8889284d1 394 Gene3D G3DSA:3.40.50.720 2 137 7.9E-44 T 12-10-2018 AFR_08220 19219fe3337b4a6c5b21c3f8889284d1 394 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 124 3.5E-26 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_08220 19219fe3337b4a6c5b21c3f8889284d1 394 SUPERFAMILY SSF55347 139 316 1.1E-36 T 12-10-2018 AFR_08220 19219fe3337b4a6c5b21c3f8889284d1 394 Gene3D G3DSA:3.30.360.10 138 387 3.9E-78 T 12-10-2018 AFR_01735 5629c8befd7eaaf6007e3ee8f257f108 264 SMART SM00346 12 98 0.0031 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_01735 5629c8befd7eaaf6007e3ee8f257f108 264 SUPERFAMILY SSF46785 12 76 1.57E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01735 5629c8befd7eaaf6007e3ee8f257f108 264 SUPERFAMILY SSF55781 92 256 3.99E-22 T 12-10-2018 AFR_01735 5629c8befd7eaaf6007e3ee8f257f108 264 Gene3D G3DSA:3.30.450.40 91 260 1.2E-23 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_01735 5629c8befd7eaaf6007e3ee8f257f108 264 Gene3D G3DSA:1.10.10.10 3 72 7.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01735 5629c8befd7eaaf6007e3ee8f257f108 264 Pfam PF09339 IclR helix-turn-helix domain 14 61 1.9E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_01735 5629c8befd7eaaf6007e3ee8f257f108 264 Pfam PF01614 Bacterial transcriptional regulator 143 258 4.2E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_33070 a88316ce07dc3d55c3fa15b44865ef9c 271 Gene3D G3DSA:3.40.50.720 3 262 1.3E-80 T 12-10-2018 AFR_33070 a88316ce07dc3d55c3fa15b44865ef9c 271 Gene3D G3DSA:3.90.25.10 134 263 1.3E-80 T 12-10-2018 AFR_33070 a88316ce07dc3d55c3fa15b44865ef9c 271 Pfam PF05368 NmrA-like family 2 215 6.8E-26 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 AFR_33070 a88316ce07dc3d55c3fa15b44865ef9c 271 SUPERFAMILY SSF51735 2 243 4.67E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SMART SM00448 623 735 7.5E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Gene3D G3DSA:3.60.40.10 852 1094 3.4E-62 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Gene3D G3DSA:1.10.287.130 336 415 1.1E-22 T 12-10-2018 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Gene3D G3DSA:3.30.565.10 1097 1221 1.6E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SUPERFAMILY SSF52172 620 752 2.56E-38 T 12-10-2018 IPR011006 CheY-like superfamily AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SMART SM00388 349 415 1.6E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Gene3D G3DSA:3.40.50.12740 622 820 2.0E-41 T 12-10-2018 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SMART SM00387 1130 1220 0.64 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SMART SM00387 461 572 5.2E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SUPERFAMILY SSF47384 337 416 4.32E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Pfam PF00072 Response regulator receiver domain 625 735 2.6E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SMART SM00331 880 1094 3.1E-39 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 467 570 5.9E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Pfam PF13581 Histidine kinase-like ATPase domain 1104 1215 5.2E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SUPERFAMILY SSF55781 212 340 2.06E-6 T 12-10-2018 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 909 1093 1.8E-47 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SUPERFAMILY SSF55874 404 570 2.1E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Gene3D G3DSA:3.30.565.10 416 574 1.2E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SUPERFAMILY SSF81606 898 1092 1.12E-7 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 SUPERFAMILY SSF55874 1096 1218 7.73E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 569 3.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 511 3.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 525 3.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 550 3.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Pfam PF00512 His Kinase A (phospho-acceptor) domain 349 415 2.4E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_36025 b0a707442bd4905108db10d1a5f1f240 1221 Gene3D G3DSA:3.30.450.20 60 183 1.7E-17 T 12-10-2018 AFR_16980 38948ab51bbb20e158a334f2715dc50e 365 SUPERFAMILY SSF55347 132 291 8.5E-28 T 12-10-2018 AFR_16980 38948ab51bbb20e158a334f2715dc50e 365 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 119 3.5E-13 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_16980 38948ab51bbb20e158a334f2715dc50e 365 Gene3D G3DSA:3.40.50.720 2 133 7.7E-26 T 12-10-2018 AFR_16980 38948ab51bbb20e158a334f2715dc50e 365 Gene3D G3DSA:3.30.360.10 134 348 1.7E-34 T 12-10-2018 AFR_16980 38948ab51bbb20e158a334f2715dc50e 365 SUPERFAMILY SSF51735 3 154 1.11E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 SUPERFAMILY SSF51735 3 230 2.63E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 Gene3D G3DSA:3.40.50.720 2 234 2.1E-80 T 12-10-2018 AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.6E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.6E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.6E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.6E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.6E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 2.6E-57 T 12-10-2018 AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 6.6E-7 T 12-10-2018 AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11040 7f8a3f9194e55b831f04d809b242ddfd 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23455 7d64d490c33a1ff2941806c52175649a 453 SUPERFAMILY SSF51905 3 212 1.51E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23455 7d64d490c33a1ff2941806c52175649a 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 334 1.4E-38 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_23455 7d64d490c33a1ff2941806c52175649a 453 Gene3D G3DSA:3.50.50.100 2 404 6.7E-98 T 12-10-2018 AFR_23455 7d64d490c33a1ff2941806c52175649a 453 SUPERFAMILY SSF51905 3 350 3.33E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23455 7d64d490c33a1ff2941806c52175649a 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.9E-7 T 12-10-2018 AFR_23455 7d64d490c33a1ff2941806c52175649a 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.9E-7 T 12-10-2018 AFR_23455 7d64d490c33a1ff2941806c52175649a 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 3.9E-7 T 12-10-2018 AFR_13260 7c65ce7264eec8b8dcd84b900ad10d64 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 2.2E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13260 7c65ce7264eec8b8dcd84b900ad10d64 203 SUPERFAMILY SSF48498 84 198 4.79E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13260 7c65ce7264eec8b8dcd84b900ad10d64 203 SUPERFAMILY SSF46689 6 82 4.99E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13260 7c65ce7264eec8b8dcd84b900ad10d64 203 Gene3D G3DSA:1.10.10.60 4 72 1.9E-28 T 12-10-2018 AFR_13260 7c65ce7264eec8b8dcd84b900ad10d64 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 7.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13260 7c65ce7264eec8b8dcd84b900ad10d64 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13260 7c65ce7264eec8b8dcd84b900ad10d64 203 Gene3D G3DSA:1.10.357.10 73 201 1.8E-30 T 12-10-2018 AFR_31525 2219d6d5fec7c76dff9030c87c659d2c 495 SUPERFAMILY SSF49785 49 177 2.38E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31525 2219d6d5fec7c76dff9030c87c659d2c 495 SMART SM00606 47 179 2.4E-37 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_31525 2219d6d5fec7c76dff9030c87c659d2c 495 Gene3D G3DSA:2.60.120.260 48 179 1.4E-36 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31525 2219d6d5fec7c76dff9030c87c659d2c 495 Pfam PF03422 Carbohydrate binding module (family 6) 55 178 4.9E-29 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_31525 2219d6d5fec7c76dff9030c87c659d2c 495 Pfam PF09362 Domain of unknown function (DUF1996) 259 470 1.5E-45 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Pfam PF00754 F5/8 type C domain 44 167 7.9E-19 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Gene3D G3DSA:2.160.20.10 726 1032 2.8E-29 T 12-10-2018 IPR012334 Pectin lyase fold AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Gene3D G3DSA:2.60.120.260 35 177 2.9E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Gene3D G3DSA:2.60.120.260 189 329 6.4E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SUPERFAMILY SSF51126 1041 1122 4.11E-6 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 858 879 1000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 949 972 510.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 973 996 970.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 1093 1115 73.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 1067 1090 1700.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 1040 1062 6.1 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 915 937 5400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00710 891 913 1300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Gene3D G3DSA:2.60.40.10 436 549 2.5E-21 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SUPERFAMILY SSF49785 33 173 6.81E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Gene3D G3DSA:2.60.40.10 330 435 2.9E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SUPERFAMILY SSF49785 184 325 1.49E-16 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SUPERFAMILY SSF51126 707 1024 4.12E-32 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Pfam PF07705 CARDB 443 542 2.3E-18 T 12-10-2018 IPR011635 CARDB domain AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 Pfam PF07705 CARDB 330 430 1.5E-21 T 12-10-2018 IPR011635 CARDB domain AFR_37540 16ae35ad13ef8305cd8564453b9e8e76 1124 SMART SM00231 35 173 1.9E-7 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 Pfam PF01926 50S ribosome-binding GTPase 195 313 1.1E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 Pfam PF01926 50S ribosome-binding GTPase 22 136 5.4E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 20 447 7.9E-152 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 Gene3D G3DSA:3.30.300.20 369 450 1.1E-24 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 PIRSF PIRSF006485 18 453 1.4E-156 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 Gene3D G3DSA:3.40.50.300 19 177 1.5E-43 T 12-10-2018 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 369 447 1.8E-23 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 173 6.6E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 194 356 8.4E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 Gene3D G3DSA:3.40.50.300 193 364 1.3E-38 T 12-10-2018 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 SUPERFAMILY SSF52540 20 189 4.76E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 Hamap MF_00195 GTPase Der [der]. 19 450 34.214 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 SMART SM00382 192 335 7.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 SMART SM00382 18 183 0.28 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 245 260 2.2E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 196 216 2.2E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_29620 c944ed51a344a58c88f6d6b3592f8806 462 SUPERFAMILY SSF52540 154 451 1.3E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13720 d8257ca796fd08a9c40ad93f1e43f08d 258 SMART SM00020 29 232 0.0031 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_13720 d8257ca796fd08a9c40ad93f1e43f08d 258 Pfam PF00089 Trypsin 40 232 1.2E-7 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_13720 d8257ca796fd08a9c40ad93f1e43f08d 258 Gene3D G3DSA:2.40.10.10 44 232 6.7E-9 T 12-10-2018 AFR_13720 d8257ca796fd08a9c40ad93f1e43f08d 258 SUPERFAMILY SSF50494 28 236 4.16E-17 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_13720 d8257ca796fd08a9c40ad93f1e43f08d 258 Gene3D G3DSA:2.40.10.10 43 226 6.7E-9 T 12-10-2018 AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 Pfam PF00106 short chain dehydrogenase 8 191 6.9E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 5.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 Gene3D G3DSA:3.40.50.720 1 260 2.1E-57 T 12-10-2018 AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.4E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.4E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.4E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.4E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.4E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21445 143f135b8cf98d64a82db5031d4d52cd 262 SUPERFAMILY SSF51735 2 259 3.77E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_20705 05b16ed89d7233bb7d9cdfab0ca59a5e 498 Gene3D G3DSA:3.40.309.10 249 450 2.9E-148 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_20705 05b16ed89d7233bb7d9cdfab0ca59a5e 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_20705 05b16ed89d7233bb7d9cdfab0ca59a5e 498 SUPERFAMILY SSF53720 2 484 6.15E-145 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_20705 05b16ed89d7233bb7d9cdfab0ca59a5e 498 Pfam PF00171 Aldehyde dehydrogenase family 19 477 9.8E-138 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_20705 05b16ed89d7233bb7d9cdfab0ca59a5e 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 481 3.9E-214 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 AFR_20705 05b16ed89d7233bb7d9cdfab0ca59a5e 498 Gene3D G3DSA:3.40.605.10 23 458 2.9E-148 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_29010 98c1aea86de1e1546a37624211b6c381 289 PRINTS PR00412 Epoxide hydrolase signature 259 281 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_29010 98c1aea86de1e1546a37624211b6c381 289 PRINTS PR00412 Epoxide hydrolase signature 36 54 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_29010 98c1aea86de1e1546a37624211b6c381 289 SUPERFAMILY SSF53474 4 285 1.01E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29010 98c1aea86de1e1546a37624211b6c381 289 Pfam PF00561 alpha/beta hydrolase fold 31 128 9.4E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_29010 98c1aea86de1e1546a37624211b6c381 289 Gene3D G3DSA:3.40.50.1820 1 285 5.2E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_31145 895f3f6ce36def3ddc73dfd1c5319675 177 SUPERFAMILY SSF54197 36 174 5.26E-40 T 12-10-2018 IPR036265 HIT-like superfamily AFR_31145 895f3f6ce36def3ddc73dfd1c5319675 177 Pfam PF01230 HIT domain 49 141 4.9E-15 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_31145 895f3f6ce36def3ddc73dfd1c5319675 177 Gene3D G3DSA:3.30.428.10 2 176 2.0E-55 T 12-10-2018 IPR036265 HIT-like superfamily AFR_04555 49c518776ec1c2aa1631369989f2f492 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04555 49c518776ec1c2aa1631369989f2f492 122 Gene3D G3DSA:2.40.150.20 1 122 4.9E-52 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04555 49c518776ec1c2aa1631369989f2f492 122 SUPERFAMILY SSF50193 2 121 2.22E-49 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04555 49c518776ec1c2aa1631369989f2f492 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 3.1E-53 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFR_04555 49c518776ec1c2aa1631369989f2f492 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.178 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFR_04555 49c518776ec1c2aa1631369989f2f492 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.9E-56 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 AFR_04555 49c518776ec1c2aa1631369989f2f492 122 SMART SM01374 1 122 8.4E-85 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFR_22970 4ac46d9edc92791a5493e28401fc6d35 481 Gene3D G3DSA:2.60.120.260 32 163 3.0E-33 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_22970 4ac46d9edc92791a5493e28401fc6d35 481 SUPERFAMILY SSF51445 171 477 1.02E-77 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_22970 4ac46d9edc92791a5493e28401fc6d35 481 SUPERFAMILY SSF49785 35 158 8.22E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_22970 4ac46d9edc92791a5493e28401fc6d35 481 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 186 437 1.1E-50 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AFR_22970 4ac46d9edc92791a5493e28401fc6d35 481 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 299 308 - T 12-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 AFR_22970 4ac46d9edc92791a5493e28401fc6d35 481 Gene3D G3DSA:3.20.20.80 169 473 2.9E-92 T 12-10-2018 AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 Gene3D G3DSA:3.40.50.970 8 389 2.0E-56 T 12-10-2018 AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 Gene3D G3DSA:3.40.50.970 418 612 1.6E-56 T 12-10-2018 AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 SUPERFAMILY SSF52518 36 372 1.88E-46 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 Pfam PF02779 Transketolase, pyrimidine binding domain 421 593 1.2E-19 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 SUPERFAMILY SSF52922 628 757 2.71E-21 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 Gene3D G3DSA:3.40.50.920 629 759 4.9E-22 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 SUPERFAMILY SSF52518 411 605 8.84E-42 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 Pfam PF00676 Dehydrogenase E1 component 134 357 5.3E-23 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 SMART SM00861 420 601 2.6E-30 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_08790 3a030c3e7b54f463edf0bde43ed0327e 760 Pfam PF02780 Transketolase, C-terminal domain 640 743 4.3E-19 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 SMART SM00344 6 110 4.7E-32 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.4E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.4E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.4E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 Gene3D G3DSA:1.10.10.10 4 55 8.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 2.0E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 Gene3D G3DSA:3.30.70.920 58 137 8.4E-20 T 12-10-2018 AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 SUPERFAMILY SSF46785 5 64 1.89E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 1.7E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_27795 eca1bc0f049f4cf7aa6580cbb5261add 151 SUPERFAMILY SSF54909 68 147 9.52E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 5.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 5.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 5.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 Pfam PF00106 short chain dehydrogenase 7 181 5.3E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 Gene3D G3DSA:3.40.50.720 1 220 1.1E-50 T 12-10-2018 AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 4.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 4.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 4.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 4.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12805 aa8b951f7e90f738012863c9e2ca93bf 222 SUPERFAMILY SSF51735 5 213 3.54E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12250 9751153a81de42680e47516560198242 136 Gene3D G3DSA:3.40.5.90 79 136 9.0E-7 T 12-10-2018 AFR_12250 9751153a81de42680e47516560198242 136 Pfam PF09360 Iron-binding zinc finger CDGSH type 109 131 5.5E-7 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 AFR_12250 9751153a81de42680e47516560198242 136 Pfam PF06902 Divergent 4Fe-4S mono-cluster 9 72 3.3E-24 T 12-10-2018 IPR010693 Divergent 4Fe-4S mono-cluster AFR_31955 690b665dcc77da8235d26ebb36898513 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 4.0E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_31955 690b665dcc77da8235d26ebb36898513 335 SUPERFAMILY SSF52540 5 257 3.22E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31955 690b665dcc77da8235d26ebb36898513 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 312 6.9E-22 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_31955 690b665dcc77da8235d26ebb36898513 335 Pfam PF00005 ABC transporter 26 187 8.1E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31955 690b665dcc77da8235d26ebb36898513 335 Gene3D G3DSA:3.40.50.300 3 333 4.3E-89 T 12-10-2018 AFR_31955 690b665dcc77da8235d26ebb36898513 335 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_31955 690b665dcc77da8235d26ebb36898513 335 SMART SM00382 34 237 1.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20930 6ba3ee1e5cb0dba810acfb7ddbd80219 365 Pfam PF00144 Beta-lactamase 16 350 6.2E-44 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_20930 6ba3ee1e5cb0dba810acfb7ddbd80219 365 Gene3D G3DSA:3.40.710.30 4 365 3.7E-110 T 12-10-2018 AFR_20930 6ba3ee1e5cb0dba810acfb7ddbd80219 365 SUPERFAMILY SSF56601 9 359 5.38E-52 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_22735 23e8bd4c07426685b808886417e5e31d 419 PIRSF PIRSF001400 1 419 6.6E-179 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 Gene3D G3DSA:3.30.390.10 1 126 1.6E-53 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFR_22735 23e8bd4c07426685b808886417e5e31d 419 SUPERFAMILY SSF54826 4 136 3.01E-52 T 12-10-2018 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 Hamap MF_00318 Enolase [eno]. 2 411 43.232 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 SMART SM01193 4 134 1.1E-87 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 SMART SM01192 139 419 9.4E-198 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 PRINTS PR00148 Enolase signature 161 174 3.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 PRINTS PR00148 Enolase signature 107 123 3.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 PRINTS PR00148 Enolase signature 311 322 3.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 PRINTS PR00148 Enolase signature 334 348 3.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 PRINTS PR00148 Enolase signature 363 380 3.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 PRINTS PR00148 Enolase signature 37 51 3.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 ProSitePatterns PS00164 Enolase signature. 334 347 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 Gene3D G3DSA:3.20.20.120 129 419 5.5E-122 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_22735 23e8bd4c07426685b808886417e5e31d 419 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 417 4.0E-193 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 SUPERFAMILY SSF51604 139 418 5.37E-121 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_22735 23e8bd4c07426685b808886417e5e31d 419 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 417 8.2E-120 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_22735 23e8bd4c07426685b808886417e5e31d 419 Pfam PF03952 Enolase, N-terminal domain 4 134 8.7E-56 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFR_13875 2d11d843a5f67539524a9f66c96a70c9 291 Gene3D G3DSA:3.40.50.720 71 260 1.0E-65 T 12-10-2018 AFR_13875 2d11d843a5f67539524a9f66c96a70c9 291 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 196 212 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFR_13875 2d11d843a5f67539524a9f66c96a70c9 291 Gene3D G3DSA:3.40.50.720 4 282 1.0E-65 T 12-10-2018 AFR_13875 2d11d843a5f67539524a9f66c96a70c9 291 SUPERFAMILY SSF52283 6 101 1.19E-16 T 12-10-2018 AFR_13875 2d11d843a5f67539524a9f66c96a70c9 291 SUPERFAMILY SSF51735 76 259 1.08E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13875 2d11d843a5f67539524a9f66c96a70c9 291 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 83 259 8.7E-38 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFR_13875 2d11d843a5f67539524a9f66c96a70c9 291 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 285 1.2E-18 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 Gene3D G3DSA:2.40.30.10 341 395 3.7E-27 T 12-10-2018 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 SUPERFAMILY SSF50465 305 395 1.09E-35 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 SUPERFAMILY SSF50447 207 304 8.32E-30 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 58.914 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 6.6E-220 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 Pfam PF03143 Elongation factor Tu C-terminal domain 303 395 1.2E-32 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 6.2E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 Gene3D G3DSA:3.40.50.300 1 205 1.1E-67 T 12-10-2018 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 6.4E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 6.4E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.4E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 6.4E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 6.4E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 SUPERFAMILY SSF52540 6 221 2.47E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 8.0E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.4E-56 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 Gene3D G3DSA:2.40.30.10 208 337 5.2E-53 T 12-10-2018 AFR_04495 8c4297dcb931a14b50d97cb8cee301bd 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_20480 ff06324f0fb2435697e73fb26748970b 187 PIRSF PIRSF000709 2 100 1.4E-5 T 12-10-2018 AFR_20480 ff06324f0fb2435697e73fb26748970b 187 SMART SM00855 3 148 1.4E-17 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_20480 ff06324f0fb2435697e73fb26748970b 187 Gene3D G3DSA:3.40.50.1240 1 187 3.1E-52 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_20480 ff06324f0fb2435697e73fb26748970b 187 SUPERFAMILY SSF53254 1 186 6.68E-47 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_20480 ff06324f0fb2435697e73fb26748970b 187 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 186 1.8E-47 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 Pfam PF00990 Diguanylate cyclase, GGDEF domain 343 498 5.6E-46 T 12-10-2018 IPR000160 GGDEF domain AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 Pfam PF00563 EAL domain 519 756 3.7E-72 T 12-10-2018 IPR001633 EAL domain AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 Gene3D G3DSA:3.30.70.270 338 516 1.5E-53 T 12-10-2018 AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 Gene3D G3DSA:3.20.20.450 517 771 4.6E-98 T 12-10-2018 IPR035919 EAL domain superfamily AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 341 502 1.9E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 SMART SM00267 332 503 3.1E-58 T 12-10-2018 IPR000160 GGDEF domain AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 SUPERFAMILY SSF55073 348 504 1.18E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 SUPERFAMILY SSF141868 518 769 4.32E-87 T 12-10-2018 IPR035919 EAL domain superfamily AFR_32930 eedb9668b205f4b8d06340ce3250d9e9 773 SMART SM00052 513 763 2.0E-108 T 12-10-2018 IPR001633 EAL domain AFR_06510 141fbae1988298e7a9136083660e6d44 196 SMART SM00479 4 179 5.5E-26 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFR_06510 141fbae1988298e7a9136083660e6d44 196 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 38.614 T 12-10-2018 IPR022894 Oligoribonuclease GO:0000175 AFR_06510 141fbae1988298e7a9136083660e6d44 196 Pfam PF00929 Exonuclease 6 169 1.4E-30 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFR_06510 141fbae1988298e7a9136083660e6d44 196 Gene3D G3DSA:3.30.420.10 2 180 8.6E-69 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_06510 141fbae1988298e7a9136083660e6d44 196 SUPERFAMILY SSF53098 4 178 4.07E-44 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_32480 9d21041f086fa54e87b3c01e86361d97 315 Pfam PF07470 Glycosyl Hydrolase Family 88 52 283 8.7E-22 T 12-10-2018 IPR010905 Glycosyl hydrolase, family 88 AFR_32480 9d21041f086fa54e87b3c01e86361d97 315 SUPERFAMILY SSF48208 18 277 1.05E-24 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_32480 9d21041f086fa54e87b3c01e86361d97 315 Gene3D G3DSA:1.50.10.10 1 305 2.0E-46 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_24490 24af044e982b38820514f357bf677149 481 Pfam PF07690 Major Facilitator Superfamily 17 417 3.1E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_24490 24af044e982b38820514f357bf677149 481 Gene3D G3DSA:1.20.1720.10 13 224 5.7E-51 T 12-10-2018 AFR_24490 24af044e982b38820514f357bf677149 481 ProSitePatterns PS00217 Sugar transport proteins signature 2. 108 133 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_24490 24af044e982b38820514f357bf677149 481 SUPERFAMILY SSF103473 8 461 6.02E-67 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_24490 24af044e982b38820514f357bf677149 481 Gene3D G3DSA:1.20.1250.20 264 469 8.5E-19 T 12-10-2018 AFR_24490 24af044e982b38820514f357bf677149 481 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 430 3.1E-69 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_24490 24af044e982b38820514f357bf677149 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 2.1E-9 T 12-10-2018 AFR_24490 24af044e982b38820514f357bf677149 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 2.1E-9 T 12-10-2018 AFR_24490 24af044e982b38820514f357bf677149 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 2.1E-9 T 12-10-2018 AFR_24490 24af044e982b38820514f357bf677149 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 2.1E-9 T 12-10-2018 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 PRINTS PR00412 Epoxide hydrolase signature 262 284 2.4E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 PRINTS PR00412 Epoxide hydrolase signature 65 80 2.4E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 PRINTS PR00412 Epoxide hydrolase signature 123 136 2.4E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 Gene3D G3DSA:3.40.50.1820 17 290 1.8E-68 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 SUPERFAMILY SSF53474 17 285 6.83E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 Pfam PF00561 alpha/beta hydrolase fold 42 274 1.2E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 9.3E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 9.3E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 9.3E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23710 b92ab845f66f92796fd8a1d8fc4a3652 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 231 245 9.3E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_05940 a627ca9dd53d9f388466e42395eabdcc 192 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 2.5E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05940 a627ca9dd53d9f388466e42395eabdcc 192 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 2.5E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05940 a627ca9dd53d9f388466e42395eabdcc 192 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 2.5E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05940 a627ca9dd53d9f388466e42395eabdcc 192 Pfam PF13411 MerR HTH family regulatory protein 8 74 3.6E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05940 a627ca9dd53d9f388466e42395eabdcc 192 SMART SM00422 7 76 4.6E-27 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05940 a627ca9dd53d9f388466e42395eabdcc 192 Gene3D G3DSA:1.10.1660.10 9 187 2.2E-32 T 12-10-2018 AFR_05940 a627ca9dd53d9f388466e42395eabdcc 192 SUPERFAMILY SSF46955 7 116 1.14E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_12595 713bedf486ed14e1d091ffd89f3d4ecf 624 Gene3D G3DSA:1.10.3720.10 351 611 2.6E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_12595 713bedf486ed14e1d091ffd89f3d4ecf 624 Gene3D G3DSA:1.10.3720.10 28 280 6.7E-66 T 12-10-2018 IPR035906 MetI-like superfamily AFR_12595 713bedf486ed14e1d091ffd89f3d4ecf 624 SUPERFAMILY SSF161098 356 624 1.01E-69 T 12-10-2018 IPR035906 MetI-like superfamily AFR_12595 713bedf486ed14e1d091ffd89f3d4ecf 624 SUPERFAMILY SSF161098 32 270 2.22E-56 T 12-10-2018 IPR035906 MetI-like superfamily AFR_12595 713bedf486ed14e1d091ffd89f3d4ecf 624 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 438 607 5.0E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_12595 713bedf486ed14e1d091ffd89f3d4ecf 624 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 63 277 1.9E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_09675 9afde04c9ed781c608bd34b28fc02d7e 305 Gene3D G3DSA:3.30.450.180 109 276 3.5E-6 T 12-10-2018 AFR_09675 9afde04c9ed781c608bd34b28fc02d7e 305 Gene3D G3DSA:1.10.260.40 3 83 1.6E-8 T 12-10-2018 AFR_09675 9afde04c9ed781c608bd34b28fc02d7e 305 SUPERFAMILY SSF47413 19 79 8.89E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_09675 9afde04c9ed781c608bd34b28fc02d7e 305 SMART SM00530 9 81 2.1E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_09675 9afde04c9ed781c608bd34b28fc02d7e 305 Pfam PF13560 Helix-turn-helix domain 5 84 3.0E-17 T 12-10-2018 AFR_21585 6d38baf6d7b9b8287c31a4e593aab6e4 343 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 169 305 4.0E-11 T 12-10-2018 AFR_21585 6d38baf6d7b9b8287c31a4e593aab6e4 343 Pfam PF12787 EcsC protein family 102 302 1.3E-22 T 12-10-2018 IPR024787 EcsC protein AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 SUPERFAMILY SSF52172 2 138 1.99E-17 T 12-10-2018 IPR011006 CheY-like superfamily AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 Pfam PF00072 Response regulator receiver domain 5 110 2.1E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 SMART SM00448 3 122 3.7E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 SMART SM00421 150 212 9.3E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 198 7.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 Gene3D G3DSA:3.40.50.12740 3 210 1.1E-43 T 12-10-2018 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26560 d49e1a9947f99beab4d7318f679da47a 216 SUPERFAMILY SSF46894 136 198 2.99E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 SUPERFAMILY SSF47090 3 64 3.66E-15 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 Gene3D G3DSA:1.10.101.10 81 144 1.5E-19 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 Gene3D G3DSA:1.10.101.10 1 68 7.5E-19 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 SUPERFAMILY SSF53187 171 357 7.85E-38 T 12-10-2018 AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 SUPERFAMILY SSF47090 82 142 1.28E-17 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 Gene3D G3DSA:3.40.630.40 171 359 1.6E-37 T 12-10-2018 AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 174 354 1.9E-34 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 SMART SM00646 239 354 1.1E-32 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 Pfam PF01471 Putative peptidoglycan binding domain 86 139 6.0E-16 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_42940 56982645ca491bcbf0adbbc03abe3ff0 383 Pfam PF01471 Putative peptidoglycan binding domain 10 64 2.6E-13 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 SUPERFAMILY SSF50370 810 936 4.33E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Gene3D G3DSA:2.120.10.30 21 483 2.6E-70 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 SUPERFAMILY SSF50952 25 464 7.72E-11 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Pfam PF00652 Ricin-type beta-trefoil lectin domain 814 934 1.0E-25 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 SMART SM00458 812 937 4.6E-30 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Pfam PF03422 Carbohydrate binding module (family 6) 684 805 8.6E-31 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Gene3D G3DSA:2.80.10.50 907 937 1.8E-10 T 12-10-2018 AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Gene3D G3DSA:2.60.120.260 674 807 2.5E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 SUPERFAMILY SSF49785 681 805 1.42E-24 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 SUPERFAMILY SSF49299 485 572 7.72E-25 T 12-10-2018 IPR035986 PKD domain superfamily AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Pfam PF07995 Glucose / Sorbosone dehydrogenase 49 326 1.1E-34 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Gene3D G3DSA:2.60.40.10 484 569 4.7E-28 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Pfam PF00801 PKD domain 493 561 3.8E-11 T 12-10-2018 IPR000601 PKD domain AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 Gene3D G3DSA:2.80.10.50 811 906 1.7E-26 T 12-10-2018 AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 SMART SM00089 489 572 1.1E-20 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_29200 ab5062a9a382b19689e5f45683e4ef86 937 SMART SM00606 676 807 4.6E-39 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 PIRSF PIRSF002599 1 67 1.2E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 SMART SM00357 3 67 1.9E-29 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 SUPERFAMILY SSF50249 1 66 3.43E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 12-10-2018 IPR019844 Cold-shock conserved site AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 PRINTS PR00050 Cold shock protein signature 40 58 2.5E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 PRINTS PR00050 Cold shock protein signature 25 34 2.5E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 PRINTS PR00050 Cold shock protein signature 4 19 2.5E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 Gene3D G3DSA:2.40.50.140 1 65 2.7E-29 T 12-10-2018 AFR_33245 f6eaca914cb65363eb49949e542d5d5d 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 2.8E-30 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_01510 c173fe93b4c02e45bec3ef8cffbad192 179 SUPERFAMILY SSF48498 67 172 1.71E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_01510 c173fe93b4c02e45bec3ef8cffbad192 179 Pfam PF13305 WHG domain 74 149 2.2E-7 T 12-10-2018 IPR025996 WHG domain AFR_01510 c173fe93b4c02e45bec3ef8cffbad192 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 38 9.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01510 c173fe93b4c02e45bec3ef8cffbad192 179 SUPERFAMILY SSF46689 2 59 1.6E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01510 c173fe93b4c02e45bec3ef8cffbad192 179 Gene3D G3DSA:1.10.357.10 45 173 1.8E-27 T 12-10-2018 AFR_01510 c173fe93b4c02e45bec3ef8cffbad192 179 Gene3D G3DSA:1.10.10.60 1 44 1.2E-13 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 ProSitePatterns PS00455 Putative AMP-binding domain signature. 591 602 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SMART SM00823 Phosphopantetheine attachment site 2565 2633 6.6E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SMART SM00823 Phosphopantetheine attachment site 943 1012 9.2E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SMART SM00823 Phosphopantetheine attachment site 1494 1564 0.0026 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 1029 1201 1.89E-50 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF56801 2006 2578 1.7E-146 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.300.30 830 934 4.9E-37 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.30 211 434 6.0E-64 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00668 Condensation domain 1577 2025 4.3E-88 T 12-10-2018 IPR001242 Condensation domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00668 Condensation domain 1026 1465 2.6E-85 T 12-10-2018 IPR001242 Condensation domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00668 Condensation domain 2668 2992 1.2E-37 T 12-10-2018 IPR001242 Condensation domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00668 Condensation domain 10 442 2.1E-45 T 12-10-2018 IPR001242 Condensation domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 ProSitePatterns PS00012 Phosphopantetheine attachment site. 967 982 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 2641 2848 1.01E-30 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 1208 1461 7.45E-55 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.40.50.12780 2033 2447 4.5E-124 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.40.50.1820 935 1032 4.8E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2589 2604 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2195 2206 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 1579 1750 1.89E-48 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 1761 2032 4.56E-60 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF47336 2559 2629 5.5E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 12 183 3.56E-30 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00501 AMP-binding enzyme 2048 2454 9.6E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00501 AMP-binding enzyme 461 836 7.4E-80 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.40.50.12780 448 829 5.6E-124 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.30 1205 1460 5.7E-144 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SMART SM01294 2566 2629 0.0093 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF47336 936 1008 1.7E-18 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2068 2479 9.1E-125 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 482 860 2.6E-119 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.10 1578 1947 2.0E-151 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 2837 3104 2.89E-31 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.300.30 2448 2552 1.2E-34 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:1.10.1200.10 2553 2634 6.0E-25 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:1.10.1200.10 1483 1565 5.7E-26 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2970 3126 5.1E-32 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF52777 190 448 9.89E-42 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.10 11 207 5.2E-48 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF13193 AMP-binding enzyme C-terminal domain 2463 2541 6.8E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF13193 AMP-binding enzyme C-terminal domain 844 918 1.4E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00550 Phosphopantetheine attachment site 946 1006 6.3E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00550 Phosphopantetheine attachment site 2568 2626 3.0E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Pfam PF00550 Phosphopantetheine attachment site 1498 1557 2.2E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF47336 1488 1560 1.44E-18 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.30 2821 3104 1.6E-79 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.30 1759 2013 2.0E-151 T 12-10-2018 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.10 2635 2819 3.7E-43 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 Gene3D G3DSA:3.30.559.10 1033 1398 5.7E-144 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_18540 685408d1cf4bd22a8d33b974346d03be 3143 SUPERFAMILY SSF56801 422 956 9.16E-143 T 12-10-2018 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 SUPERFAMILY SSF53790 1 236 8.64E-48 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 Gene3D G3DSA:3.40.1010.10 2 134 6.9E-33 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 Gene3D G3DSA:3.30.950.10 368 503 5.9E-52 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 Gene3D G3DSA:3.30.950.10 136 251 5.0E-14 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 215 6.6E-48 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 259 466 2.2E-37 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 101 133 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 Gene3D G3DSA:3.40.1010.10 252 367 1.1E-28 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 SUPERFAMILY SSF53790 256 487 2.75E-55 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 259 501 1.2E-86 T 12-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 AFR_33990 0f20f3a0d4d18b88135bf2293cee1685 503 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 234 4.5E-65 T 12-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 AFR_11235 538220ad71702a1dfbb5908da7268747 559 Gene3D G3DSA:1.10.150.20 341 480 2.2E-24 T 12-10-2018 AFR_11235 538220ad71702a1dfbb5908da7268747 559 SMART SM00482 318 518 5.0E-10 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_11235 538220ad71702a1dfbb5908da7268747 559 Gene3D G3DSA:3.30.70.370 304 549 2.2E-24 T 12-10-2018 AFR_11235 538220ad71702a1dfbb5908da7268747 559 Pfam PF00476 DNA polymerase family A 211 550 8.5E-25 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_11235 538220ad71702a1dfbb5908da7268747 559 SUPERFAMILY SSF56672 164 558 1.89E-61 T 12-10-2018 AFR_00285 62179eccd3279d8498cd30e4109f51ab 501 SUPERFAMILY SSF56601 98 496 2.36E-73 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_00285 62179eccd3279d8498cd30e4109f51ab 501 Gene3D G3DSA:3.40.710.10 137 489 2.0E-121 T 12-10-2018 AFR_00285 62179eccd3279d8498cd30e4109f51ab 501 Gene3D G3DSA:3.90.1310.10 57 398 2.0E-121 T 12-10-2018 AFR_00285 62179eccd3279d8498cd30e4109f51ab 501 Pfam PF00905 Penicillin binding protein transpeptidase domain 160 486 3.8E-60 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_34055 9fb696956006fd7b867639896368f51b 699 Gene3D G3DSA:3.30.70.1440 116 165 1.7E-8 T 12-10-2018 AFR_34055 9fb696956006fd7b867639896368f51b 699 SUPERFAMILY SSF82866 454 673 5.89E-27 T 12-10-2018 AFR_34055 9fb696956006fd7b867639896368f51b 699 SUPERFAMILY SSF82866 109 335 2.09E-32 T 12-10-2018 AFR_34055 9fb696956006fd7b867639896368f51b 699 Gene3D G3DSA:1.20.1640.10 166 324 1.7E-8 T 12-10-2018 AFR_34055 9fb696956006fd7b867639896368f51b 699 Pfam PF03176 MMPL family 40 361 5.8E-62 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_34055 9fb696956006fd7b867639896368f51b 699 Pfam PF03176 MMPL family 462 680 2.9E-52 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_34565 344a23a7c057470dd8fc0279fcd72de9 380 Gene3D G3DSA:1.20.1250.20 3 376 1.8E-25 T 12-10-2018 AFR_34565 344a23a7c057470dd8fc0279fcd72de9 380 SUPERFAMILY SSF103473 10 374 2.88E-27 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_34565 344a23a7c057470dd8fc0279fcd72de9 380 Pfam PF07690 Major Facilitator Superfamily 10 339 8.9E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_24410 d9027b24dc98d01f9dd1feb6eaa3ff19 286 Gene3D G3DSA:3.60.130.10 3 286 4.4E-89 T 12-10-2018 AFR_24410 d9027b24dc98d01f9dd1feb6eaa3ff19 286 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 11 275 1.0E-56 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 AFR_24410 d9027b24dc98d01f9dd1feb6eaa3ff19 286 SUPERFAMILY SSF51197 9 282 2.66E-82 T 12-10-2018 AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 SMART SM00458 637 773 0.0013 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 58 574 4.0E-139 T 12-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 Gene3D G3DSA:2.80.10.50 591 721 3.1E-19 T 12-10-2018 AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 Gene3D G3DSA:2.80.10.50 722 775 6.7E-11 T 12-10-2018 AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 SUPERFAMILY SSF48208 112 399 3.66E-12 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 721 775 2.4E-9 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 629 713 3.2E-14 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29175 de1a0afe620da746281dc2d7a2e310e5 776 SUPERFAMILY SSF50370 637 773 6.17E-35 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_23440 187ee715d0e0885a785774369cc1e639 112 Pfam PF13564 DoxX-like family 4 103 5.3E-14 T 12-10-2018 IPR032808 DoxX family AFR_17795 8a9d5d8a859b69c6a318fce7993a560f 305 Gene3D G3DSA:3.40.190.10 149 249 6.3E-60 T 12-10-2018 AFR_17795 8a9d5d8a859b69c6a318fce7993a560f 305 Gene3D G3DSA:3.40.190.10 59 280 6.3E-60 T 12-10-2018 AFR_17795 8a9d5d8a859b69c6a318fce7993a560f 305 SUPERFAMILY SSF53850 15 289 6.42E-51 T 12-10-2018 AFR_17795 8a9d5d8a859b69c6a318fce7993a560f 305 SMART SM00062 62 291 3.1E-40 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_17795 8a9d5d8a859b69c6a318fce7993a560f 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 63 288 4.9E-54 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 Pfam PF07690 Major Facilitator Superfamily 32 419 3.6E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 Gene3D G3DSA:1.20.1720.10 24 257 8.6E-44 T 12-10-2018 AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 SUPERFAMILY SSF103473 7 470 1.44E-70 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 430 1.6E-85 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 1.3E-10 T 12-10-2018 AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.3E-10 T 12-10-2018 AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.3E-10 T 12-10-2018 AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 311 335 1.3E-10 T 12-10-2018 AFR_20010 4ec11d2b14fad88083e3e36b75f556d9 472 Gene3D G3DSA:1.20.1250.20 268 468 1.1E-20 T 12-10-2018 AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 Pfam PF01483 Proprotein convertase P-domain 496 574 1.2E-18 T 12-10-2018 IPR002884 P domain GO:0004252|GO:0006508 AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 208 7.0E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 PRINTS PR00723 Subtilisin serine protease family (S8) signature 348 364 7.0E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 PRINTS PR00723 Subtilisin serine protease family (S8) signature 157 176 7.0E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 SUPERFAMILY SSF52743 135 398 5.37E-77 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 162 173 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 SUPERFAMILY SSF49785 470 574 6.38E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 Gene3D G3DSA:2.60.120.260 460 574 5.5E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 199 209 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 349 359 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 Pfam PF05922 Peptidase inhibitor I9 57 127 3.4E-7 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 Gene3D G3DSA:3.30.70.80 48 127 1.2E-19 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 SUPERFAMILY SSF54897 56 127 1.87E-11 T 12-10-2018 AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 Gene3D G3DSA:3.40.50.200 129 405 1.1E-90 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_40340 c57b2a0c528723e21554de0a52886c0f 574 Pfam PF00082 Subtilase family 163 386 1.2E-37 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_41305 6895f372dee18bdcaf2f3b56dc4c4eaa 239 Gene3D G3DSA:3.40.50.150 7 199 8.3E-35 T 12-10-2018 AFR_41305 6895f372dee18bdcaf2f3b56dc4c4eaa 239 Pfam PF08241 Methyltransferase domain 49 138 4.8E-20 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_41305 6895f372dee18bdcaf2f3b56dc4c4eaa 239 SUPERFAMILY SSF53335 8 203 3.75E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_40165 ae4208715833e93ba82192e23949df30 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 323 7.3E-135 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 PIRSF PIRSF001415 1 328 7.1E-141 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 Gene3D G3DSA:3.20.20.70 1 329 1.0E-133 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_40165 ae4208715833e93ba82192e23949df30 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 124 138 4.3E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 299 318 4.3E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 193 212 4.3E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 244 260 4.3E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 269 284 4.3E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 155 174 4.3E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 SMART SM01004 3 325 4.7E-211 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_40165 ae4208715833e93ba82192e23949df30 329 SUPERFAMILY SSF51569 2 327 2.2E-128 T 12-10-2018 AFR_40165 ae4208715833e93ba82192e23949df30 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 244 256 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFR_27575 95cf18376a321c418761e9314b8881cf 260 Gene3D G3DSA:3.40.50.300 2 254 9.7E-64 T 12-10-2018 AFR_27575 95cf18376a321c418761e9314b8881cf 260 SUPERFAMILY SSF52540 4 226 1.28E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27575 95cf18376a321c418761e9314b8881cf 260 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_27575 95cf18376a321c418761e9314b8881cf 260 SMART SM00382 33 216 3.0E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_27575 95cf18376a321c418761e9314b8881cf 260 Pfam PF00005 ABC transporter 24 165 1.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 SMART SM00382 99 310 6.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 Gene3D G3DSA:1.10.260.30 330 449 2.3E-40 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 Gene3D G3DSA:3.40.50.300 90 287 4.5E-119 T 12-10-2018 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 Pfam PF02978 Signal peptide binding domain 330 428 8.2E-31 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 2.9E-69 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 SUPERFAMILY SSF52540 42 357 2.02E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 SMART SM00963 1 86 8.8E-36 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 438 33.662 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 Gene3D G3DSA:1.20.120.140 5 308 4.5E-119 T 12-10-2018 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 5.6E-176 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 SMART SM00962 100 298 2.0E-104 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.7E-23 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFR_36370 bc5db268b5bf25a841abc0d27630a66d 517 SUPERFAMILY SSF47446 330 432 5.72E-34 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFR_22155 a2c12be349d97dcd5ead96f965cf755b 318 Pfam PF00296 Luciferase-like monooxygenase 8 291 1.9E-41 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_22155 a2c12be349d97dcd5ead96f965cf755b 318 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 5 318 3.2E-79 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related AFR_22155 a2c12be349d97dcd5ead96f965cf755b 318 Gene3D G3DSA:3.20.20.30 1 318 3.4E-54 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22155 a2c12be349d97dcd5ead96f965cf755b 318 TIGRFAM TIGR03885 flavin_revert: probable non-F420 flavinoid oxidoreductase 5 317 3.5E-144 T 12-10-2018 IPR023907 Non-F420 flavinoid oxidoreductase AFR_22155 a2c12be349d97dcd5ead96f965cf755b 318 SUPERFAMILY SSF51679 2 318 8.77E-52 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_01630 cb11741b783c6c617bc0fb4bf72483f1 413 SUPERFAMILY SSF102114 17 365 2.22E-46 T 12-10-2018 AFR_01630 cb11741b783c6c617bc0fb4bf72483f1 413 PIRSF PIRSF004762 1 386 2.5E-101 T 12-10-2018 AFR_01630 cb11741b783c6c617bc0fb4bf72483f1 413 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 54 373 9.3E-103 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AFR_01630 cb11741b783c6c617bc0fb4bf72483f1 413 Gene3D G3DSA:3.20.20.70 2 372 1.9E-56 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_01630 cb11741b783c6c617bc0fb4bf72483f1 413 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 376 50.101 T 12-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFR_01630 cb11741b783c6c617bc0fb4bf72483f1 413 Pfam PF04055 Radical SAM superfamily 63 235 1.7E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_01630 cb11741b783c6c617bc0fb4bf72483f1 413 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 373 5.8E-140 T 12-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFR_23245 7ea62abb4168f72be0f9a2cc757d48b3 125 SMART SM00418 3 81 2.9E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_23245 7ea62abb4168f72be0f9a2cc757d48b3 125 SUPERFAMILY SSF46785 2 85 2.61E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23245 7ea62abb4168f72be0f9a2cc757d48b3 125 Gene3D G3DSA:1.10.10.10 2 114 1.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23245 7ea62abb4168f72be0f9a2cc757d48b3 125 Pfam PF12840 Helix-turn-helix domain 2 61 1.3E-16 T 12-10-2018 AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 SUPERFAMILY SSF46894 289 379 1.56E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 Gene3D G3DSA:1.10.10.10 287 381 9.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 Pfam PF02602 Uroporphyrinogen-III synthase HemD 37 276 7.1E-40 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 Gene3D G3DSA:3.40.50.10090 56 194 2.9E-67 T 12-10-2018 AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 Pfam PF00486 Transcriptional regulatory protein, C terminal 312 377 3.6E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 Gene3D G3DSA:3.40.50.10090 29 275 2.9E-67 T 12-10-2018 AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 SMART SM00862 308 377 1.0E-13 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_18665 2a8bd50c1f3eb360b9502ed2d3f70643 381 SUPERFAMILY SSF69618 25 284 1.83E-54 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_32170 4da0d5c49a128520158d5dddbdfc2a5c 334 SUPERFAMILY SSF52833 20 92 2.46E-5 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_32170 4da0d5c49a128520158d5dddbdfc2a5c 334 SUPERFAMILY SSF47616 167 322 1.81E-34 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFR_32170 4da0d5c49a128520158d5dddbdfc2a5c 334 Gene3D G3DSA:3.40.30.130 1 158 3.5E-57 T 12-10-2018 AFR_32170 4da0d5c49a128520158d5dddbdfc2a5c 334 Pfam PF13409 Glutathione S-transferase, N-terminal domain 43 132 1.7E-11 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFR_32170 4da0d5c49a128520158d5dddbdfc2a5c 334 Pfam PF13410 Glutathione S-transferase, C-terminal domain 184 253 5.6E-11 T 12-10-2018 AFR_32170 4da0d5c49a128520158d5dddbdfc2a5c 334 Gene3D G3DSA:1.20.1050.10 159 333 4.0E-76 T 12-10-2018 AFR_32170 4da0d5c49a128520158d5dddbdfc2a5c 334 PIRSF PIRSF015753 2 304 3.7E-110 T 12-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 AFR_02910 46c95c5c02b98ee0258e9f8b6182bafd 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 81 97 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_02910 46c95c5c02b98ee0258e9f8b6182bafd 409 Pfam PF07690 Major Facilitator Superfamily 34 364 9.2E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_02910 46c95c5c02b98ee0258e9f8b6182bafd 409 SUPERFAMILY SSF103473 24 405 3.79E-38 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_02910 46c95c5c02b98ee0258e9f8b6182bafd 409 Gene3D G3DSA:1.20.1250.20 20 406 3.7E-34 T 12-10-2018 AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 SUPERFAMILY SSF53448 128 550 7.67E-18 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 Gene3D G3DSA:3.90.550.10 349 501 2.9E-21 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 Gene3D G3DSA:3.90.550.10 119 210 1.9E-6 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 SMART SM00052 783 998 4.2E-15 T 12-10-2018 IPR001633 EAL domain AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 SUPERFAMILY SSF141868 789 1000 1.96E-42 T 12-10-2018 IPR035919 EAL domain superfamily AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 Gene3D G3DSA:3.20.20.450 783 1004 1.7E-43 T 12-10-2018 IPR035919 EAL domain superfamily AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 Pfam PF13632 Glycosyl transferase family group 2 363 582 2.4E-25 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_28315 7a311b046349a7cacfa67be7bd3d52d9 1006 Pfam PF00563 EAL domain 787 993 3.3E-41 T 12-10-2018 IPR001633 EAL domain AFR_00015 e12bf110481f7fda57a706621c579fd9 290 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 2.1E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 2.1E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 2.1E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 2.1E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 2.1E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 SUPERFAMILY SSF51735 1 143 1.72E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_00015 e12bf110481f7fda57a706621c579fd9 290 SMART SM01350 160 290 0.0017 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 143 9.1E-38 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 289 8.9E-105 T 12-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 Gene3D G3DSA:1.10.1040.10 159 290 2.1E-46 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 1.2E-20 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 SUPERFAMILY SSF48179 158 289 3.74E-37 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_00015 e12bf110481f7fda57a706621c579fd9 290 Gene3D G3DSA:3.40.50.720 1 158 3.5E-45 T 12-10-2018 AFR_33960 4212fa37dcaa993124177cd1581455af 151 SUPERFAMILY SSF54736 72 137 2.62E-6 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFR_33960 4212fa37dcaa993124177cd1581455af 151 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 73 137 4.0E-4 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07685 c9e5257a024178f87b1860de421233ad 85 SUPERFAMILY SSF110324 2 82 3.84E-30 T 12-10-2018 AFR_07685 c9e5257a024178f87b1860de421233ad 85 Pfam PF01016 Ribosomal L27 protein 2 80 6.4E-35 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07685 c9e5257a024178f87b1860de421233ad 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 5.5E-35 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07685 c9e5257a024178f87b1860de421233ad 85 Gene3D G3DSA:2.40.50.100 20 84 9.6E-26 T 12-10-2018 AFR_07685 c9e5257a024178f87b1860de421233ad 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.528 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07685 c9e5257a024178f87b1860de421233ad 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_07685 c9e5257a024178f87b1860de421233ad 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.5E-34 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07685 c9e5257a024178f87b1860de421233ad 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.5E-34 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07685 c9e5257a024178f87b1860de421233ad 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.5E-34 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_07685 c9e5257a024178f87b1860de421233ad 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 2.0E-13 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 102.419 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 Pfam PF00633 Helix-hairpin-helix motif 2 27 1.1E-5 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 SUPERFAMILY SSF111304 2 196 2.35E-72 T 12-10-2018 IPR023627 Recombination protein RecR AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 Gene3D G3DSA:1.10.8.420 1 51 1.0E-19 T 12-10-2018 AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 Pfam PF02132 RecR protein 38 76 3.6E-12 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 Pfam PF13662 Toprim domain 80 170 5.4E-24 T 12-10-2018 IPR006171 TOPRIM domain AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 SMART SM00493 79 164 1.5E-16 T 12-10-2018 IPR006171 TOPRIM domain AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 1.5E-81 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 Gene3D G3DSA:3.40.1360.10 76 197 4.5E-46 T 12-10-2018 AFR_41800 94ca5de00d295bf12bdba8534d548b7c 197 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 Pfam PF03462 PCRF domain 11 204 4.8E-62 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 SMART SM00937 64 179 1.3E-47 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 SUPERFAMILY SSF75620 9 353 2.75E-120 T 12-10-2018 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 4 354 1.2E-140 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 Pfam PF00472 RF-1 domain 212 321 6.5E-39 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 Gene3D G3DSA:3.30.160.20 223 285 2.8E-31 T 12-10-2018 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 Gene3D G3DSA:1.20.58.410 5 97 1.7E-5 T 12-10-2018 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 Gene3D G3DSA:3.30.70.1660 101 222 1.9E-42 T 12-10-2018 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 Gene3D G3DSA:3.30.70.1660 286 362 7.0E-14 T 12-10-2018 AFR_37420 7af52ba5da4d07ad7fdb886f35d77fb0 363 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 2 357 36.392 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFR_36805 23657620f2686b339f6847b2ff014870 448 SUPERFAMILY SSF63411 247 433 7.17E-36 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_36805 23657620f2686b339f6847b2ff014870 448 Pfam PF00675 Insulinase (Peptidase family M16) 31 138 1.9E-9 T 12-10-2018 IPR011765 Peptidase M16, N-terminal AFR_36805 23657620f2686b339f6847b2ff014870 448 Pfam PF05193 Peptidase M16 inactive domain 185 354 4.8E-14 T 12-10-2018 IPR007863 Peptidase M16, C-terminal AFR_36805 23657620f2686b339f6847b2ff014870 448 SUPERFAMILY SSF63411 19 223 9.67E-30 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_36805 23657620f2686b339f6847b2ff014870 448 Gene3D G3DSA:3.30.830.10 27 229 1.4E-29 T 12-10-2018 AFR_36805 23657620f2686b339f6847b2ff014870 448 Gene3D G3DSA:3.30.830.10 236 435 2.0E-42 T 12-10-2018 AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 Pfam PF00563 EAL domain 505 743 7.9E-70 T 12-10-2018 IPR001633 EAL domain AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 SMART SM00052 499 748 4.0E-99 T 12-10-2018 IPR001633 EAL domain AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 331 487 3.3E-35 T 12-10-2018 IPR000160 GGDEF domain AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 SUPERFAMILY SSF55073 339 490 4.47E-42 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 SMART SM00267 323 489 1.5E-56 T 12-10-2018 IPR000160 GGDEF domain AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 Gene3D G3DSA:3.20.20.450 502 758 1.5E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 SUPERFAMILY SSF141868 505 753 3.4E-80 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 Pfam PF00990 Diguanylate cyclase, GGDEF domain 334 485 1.4E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_17345 410a7e2bb80d4a1c01f76108020caa62 765 Gene3D G3DSA:3.30.70.270 328 501 1.1E-49 T 12-10-2018 AFR_39835 8fe98dfed05a7b5522b352deedab570a 282 SUPERFAMILY SSF53790 2 219 4.19E-71 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_39835 8fe98dfed05a7b5522b352deedab570a 282 Gene3D G3DSA:3.30.950.10 110 225 4.2E-41 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFR_39835 8fe98dfed05a7b5522b352deedab570a 282 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 203 3.2E-31 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_39835 8fe98dfed05a7b5522b352deedab570a 282 PIRSF PIRSF005917 1 276 8.5E-88 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFR_39835 8fe98dfed05a7b5522b352deedab570a 282 Gene3D G3DSA:3.40.1010.10 1 109 1.6E-27 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_39835 8fe98dfed05a7b5522b352deedab570a 282 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 1 221 31.82 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFR_39835 8fe98dfed05a7b5522b352deedab570a 282 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 3 273 2.4E-59 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFR_31725 46ed869d14d645bbc15b63058416084d 641 Pfam PF00664 ABC transporter transmembrane region 83 354 1.3E-38 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_31725 46ed869d14d645bbc15b63058416084d 641 Pfam PF00005 ABC transporter 416 565 2.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31725 46ed869d14d645bbc15b63058416084d 641 SUPERFAMILY SSF90123 70 381 5.23E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_31725 46ed869d14d645bbc15b63058416084d 641 Gene3D G3DSA:3.40.50.300 393 640 5.0E-88 T 12-10-2018 AFR_31725 46ed869d14d645bbc15b63058416084d 641 Gene3D G3DSA:1.20.1560.10 61 384 2.3E-71 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_31725 46ed869d14d645bbc15b63058416084d 641 SUPERFAMILY SSF52540 390 634 6.01E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31725 46ed869d14d645bbc15b63058416084d 641 ProSitePatterns PS00211 ABC transporters family signature. 537 551 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_31725 46ed869d14d645bbc15b63058416084d 641 SMART SM00382 425 617 2.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 Gene3D G3DSA:2.160.10.10 291 409 4.3E-37 T 12-10-2018 AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 SUPERFAMILY SSF53448 4 379 2.14E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 382 6.3E-133 T 12-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 SUPERFAMILY SSF51161 298 402 3.05E-18 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 Pfam PF00483 Nucleotidyl transferase 7 275 1.3E-65 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 96 104 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 195 205 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 Gene3D G3DSA:3.90.550.10 2 290 2.5E-76 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_21020 88cca43f187e66f50cbd9073fb7cdd39 410 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 2 408 46.159 T 12-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 SUPERFAMILY SSF49899 628 860 1.37E-18 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 Gene3D G3DSA:2.60.120.200 973 1152 1.8E-20 T 12-10-2018 AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 Gene3D G3DSA:2.60.120.200 692 903 6.6E-22 T 12-10-2018 AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 SMART SM00560 711 860 1.0E-10 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 SMART SM00560 984 1138 3.0E-4 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 981 1141 2.1E-16 T 12-10-2018 AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 695 860 1.3E-20 T 12-10-2018 AFR_32595 79334f7bc3d64ef25f583a2ec72ac463 1152 SUPERFAMILY SSF49899 968 1146 7.82E-17 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_27495 3e02cc0a0fb40a7f7e252f5f3d398722 382 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 292 309 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AFR_27495 3e02cc0a0fb40a7f7e252f5f3d398722 382 SUPERFAMILY SSF51445 69 380 2.74E-56 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27495 3e02cc0a0fb40a7f7e252f5f3d398722 382 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 372 1.8E-43 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_27495 3e02cc0a0fb40a7f7e252f5f3d398722 382 Gene3D G3DSA:3.20.20.300 48 376 8.4E-84 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_25250 29365b222a044bb762fdf71db0f110f0 376 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 3.8E-16 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_25250 29365b222a044bb762fdf71db0f110f0 376 SUPERFAMILY SSF55347 126 263 1.59E-9 T 12-10-2018 AFR_25250 29365b222a044bb762fdf71db0f110f0 376 Gene3D G3DSA:3.40.50.720 1 131 1.2E-25 T 12-10-2018 AFR_25250 29365b222a044bb762fdf71db0f110f0 376 Gene3D G3DSA:3.30.360.10 132 267 4.4E-18 T 12-10-2018 AFR_25250 29365b222a044bb762fdf71db0f110f0 376 SUPERFAMILY SSF51735 1 147 2.04E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41175 a31437e32908754d7d9247094ad4977c 241 SMART SM00382 31 217 2.7E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41175 a31437e32908754d7d9247094ad4977c 241 SUPERFAMILY SSF52540 5 221 1.7E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41175 a31437e32908754d7d9247094ad4977c 241 Gene3D G3DSA:3.40.50.300 4 237 7.5E-70 T 12-10-2018 AFR_41175 a31437e32908754d7d9247094ad4977c 241 Pfam PF00005 ABC transporter 22 168 4.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_41175 a31437e32908754d7d9247094ad4977c 241 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_08860 2aaebe175328680a95e5759e4df97347 193 SUPERFAMILY SSF51182 77 178 1.04E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_08860 2aaebe175328680a95e5759e4df97347 193 SMART SM00530 15 70 2.1E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_08860 2aaebe175328680a95e5759e4df97347 193 SUPERFAMILY SSF47413 5 77 2.11E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_08860 2aaebe175328680a95e5759e4df97347 193 Gene3D G3DSA:2.60.120.10 88 178 2.2E-13 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_08860 2aaebe175328680a95e5759e4df97347 193 Pfam PF07883 Cupin domain 115 178 9.2E-14 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_08860 2aaebe175328680a95e5759e4df97347 193 Gene3D G3DSA:1.10.260.40 1 76 2.9E-16 T 12-10-2018 AFR_08860 2aaebe175328680a95e5759e4df97347 193 Pfam PF01381 Helix-turn-helix 16 70 1.2E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 SUPERFAMILY SSF46894 833 896 1.16E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 Pfam PF13191 AAA ATPase domain 4 155 1.3E-18 T 12-10-2018 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 Gene3D G3DSA:1.10.10.10 795 903 3.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 Gene3D G3DSA:1.25.40.10 531 755 2.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 ProSitePatterns PS00622 LuxR-type HTH domain signature. 857 884 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 857 873 1.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 873 885 1.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 843 857 1.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 SUPERFAMILY SSF52540 4 220 4.28E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 SUPERFAMILY SSF48452 549 696 9.28E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 Pfam PF00196 Bacterial regulatory proteins, luxR family 842 895 1.6E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33500 b5d8453eefdf22a5cdbca79452260a63 906 SMART SM00421 840 897 1.0E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 143 152 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 SUPERFAMILY SSF53738 303 440 1.88E-26 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 465 521 1.2E-7 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 228 247 8.4E-9 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 295 310 8.4E-9 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 142 156 8.4E-9 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Gene3D G3DSA:3.40.120.10 210 319 2.9E-22 T 12-10-2018 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 SUPERFAMILY SSF55957 430 515 2.22E-10 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Gene3D G3DSA:3.40.120.10 323 439 4.6E-28 T 12-10-2018 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 49 189 3.4E-36 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 214 316 6.8E-26 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 SUPERFAMILY SSF53738 40 235 2.55E-40 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 SUPERFAMILY SSF53738 214 310 3.59E-18 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Gene3D G3DSA:3.30.310.50 446 532 1.1E-6 T 12-10-2018 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 432 5.6E-18 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFR_39470 cd080fe6f094d7b99df70bb07f9f20ec 549 Gene3D G3DSA:3.40.120.10 40 197 1.9E-41 T 12-10-2018 AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 Pfam PF04542 Sigma-70 region 2 5 71 2.6E-23 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 SUPERFAMILY SSF88659 119 178 2.62E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 Gene3D G3DSA:3.10.450.50 186 307 4.3E-16 T 12-10-2018 AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 Gene3D G3DSA:1.10.1740.10 1 73 1.6E-21 T 12-10-2018 AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 SUPERFAMILY SSF88946 9 77 8.37E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 Pfam PF12680 SnoaL-like domain 194 289 1.1E-7 T 12-10-2018 IPR037401 SnoaL-like domain AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 Pfam PF08281 Sigma-70, region 4 124 174 3.2E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 SUPERFAMILY SSF54427 185 298 7.91E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 2 296 8.7E-106 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 Gene3D G3DSA:1.10.10.10 108 180 3.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26280 d21f39d5eefca052948895c7dd8bd793 316 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 178 9.2E-27 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02620 2359747f9128d845b196cbeb911726d3 347 Gene3D G3DSA:3.40.50.10740 4 160 5.1E-38 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal AFR_02620 2359747f9128d845b196cbeb911726d3 347 Gene3D G3DSA:3.50.30.60 162 346 7.4E-34 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_02620 2359747f9128d845b196cbeb911726d3 347 SUPERFAMILY SSF141986 192 340 1.57E-10 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_02620 2359747f9128d845b196cbeb911726d3 347 Pfam PF02016 LD-carboxypeptidase 17 336 8.7E-51 T 12-10-2018 IPR003507 Peptidase family S66 AFR_02620 2359747f9128d845b196cbeb911726d3 347 SUPERFAMILY SSF52317 7 160 4.07E-31 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 Gene3D G3DSA:1.10.1740.10 13 95 2.3E-19 T 12-10-2018 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 Pfam PF04539 Sigma-70 region 3 109 161 5.5E-7 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 SUPERFAMILY SSF88659 167 244 6.17E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 PRINTS PR00046 Major sigma-70 factor signature 195 207 8.9E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 PRINTS PR00046 Major sigma-70 factor signature 53 66 8.9E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 PRINTS PR00046 Major sigma-70 factor signature 212 227 8.9E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 PRINTS PR00046 Major sigma-70 factor signature 227 238 8.9E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 241 8.7E-26 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 SUPERFAMILY SSF88946 17 98 8.01E-19 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 Gene3D G3DSA:1.20.140.160 97 245 6.5E-34 T 12-10-2018 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 Pfam PF04542 Sigma-70 region 2 26 98 3.6E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 Pfam PF04545 Sigma-70, region 4 191 240 7.0E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_30935 289213c6aa142c7dcd4c35faaf2cdd30 300 SUPERFAMILY SSF88659 100 160 1.22E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 SMART SM00421 152 209 5.2E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 Pfam PF00072 Response regulator receiver domain 5 117 9.8E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 SUPERFAMILY SSF52172 3 136 1.57E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 SUPERFAMILY SSF46894 146 211 5.1E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 7.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 7.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 7.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 SMART SM00448 3 118 1.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 8.8E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33335 5ecc65eb4a67aaed7bc6869ebb53006c 217 Gene3D G3DSA:3.40.50.12740 3 213 4.5E-66 T 12-10-2018 AFR_35915 f7803c449046449e474478744a3db0fb 89 SUPERFAMILY SSF47060 3 89 1.09E-34 T 12-10-2018 IPR009068 S15/NS1, RNA-binding AFR_35915 f7803c449046449e474478744a3db0fb 89 SMART SM01387 8 88 1.5E-51 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_35915 f7803c449046449e474478744a3db0fb 89 Gene3D G3DSA:1.10.287.10 1 89 2.3E-34 T 12-10-2018 AFR_35915 f7803c449046449e474478744a3db0fb 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 4.0E-22 T 12-10-2018 AFR_35915 f7803c449046449e474478744a3db0fb 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_35915 f7803c449046449e474478744a3db0fb 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.651 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_35915 f7803c449046449e474478744a3db0fb 89 Pfam PF00312 Ribosomal protein S15 8 88 6.4E-37 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_35915 f7803c449046449e474478744a3db0fb 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.8E-39 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Gene3D G3DSA:1.10.8.280 292 409 1.1E-259 T 12-10-2018 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Gene3D G3DSA:1.20.1580.10 91 498 1.1E-259 T 12-10-2018 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 930 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 SUPERFAMILY SSF52540 9 575 6.45E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10535 b7b48b54516b97ce36110db0257c299b 985 SMART SM00382 638 904 0.0073 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10535 b7b48b54516b97ce36110db0257c299b 985 ProSitePatterns PS00211 ABC transporters family signature. 835 849 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Gene3D G3DSA:1.20.1580.10 697 835 1.1E-143 T 12-10-2018 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 SUPERFAMILY SSF52540 625 914 4.37E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 945 22.755 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Gene3D G3DSA:3.40.50.300 6 601 1.1E-259 T 12-10-2018 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Pfam PF00005 ABC transporter 629 865 2.9E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Gene3D G3DSA:3.40.50.300 622 941 1.1E-143 T 12-10-2018 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 Gene3D G3DSA:3.30.190.20 131 248 1.1E-259 T 12-10-2018 AFR_10535 b7b48b54516b97ce36110db0257c299b 985 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_15440 f6615ec4bb367834ead2ee3de97c7664 418 Gene3D G3DSA:3.40.50.1820 177 418 4.9E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15440 f6615ec4bb367834ead2ee3de97c7664 418 SUPERFAMILY SSF53474 180 372 7.65E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15440 f6615ec4bb367834ead2ee3de97c7664 418 Pfam PF10503 Esterase PHB depolymerase 191 316 7.8E-9 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AFR_15440 f6615ec4bb367834ead2ee3de97c7664 418 Gene3D G3DSA:2.60.40.2180 35 170 1.3E-6 T 12-10-2018 AFR_09825 b225669d3ff9e58cc97a9fbaa1fff545 476 Pfam PF01593 Flavin containing amine oxidoreductase 8 267 1.0E-17 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_09825 b225669d3ff9e58cc97a9fbaa1fff545 476 Gene3D G3DSA:3.50.50.60 1 66 7.9E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09825 b225669d3ff9e58cc97a9fbaa1fff545 476 Gene3D G3DSA:3.50.50.60 190 285 4.5E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09825 b225669d3ff9e58cc97a9fbaa1fff545 476 SUPERFAMILY SSF51905 1 473 5.65E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09825 b225669d3ff9e58cc97a9fbaa1fff545 476 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 1 473 9.0E-89 T 12-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 AFR_08000 e9ab7a083c3b72f01f5c75e78aae788a 259 SUPERFAMILY SSF64005 21 245 5.36E-82 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFR_08000 e9ab7a083c3b72f01f5c75e78aae788a 259 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 22 250 36.698 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFR_08000 e9ab7a083c3b72f01f5c75e78aae788a 259 Gene3D G3DSA:3.40.1180.10 2 244 3.5E-93 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFR_08000 e9ab7a083c3b72f01f5c75e78aae788a 259 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 195 212 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 AFR_08000 e9ab7a083c3b72f01f5c75e78aae788a 259 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 22 249 2.8E-73 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFR_08000 e9ab7a083c3b72f01f5c75e78aae788a 259 Pfam PF01255 Putative undecaprenyl diphosphate synthase 29 249 1.3E-73 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFR_21720 24890375496394e7c9310a776d92cbbf 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 270 286 2.4E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_21720 24890375496394e7c9310a776d92cbbf 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 61 80 2.4E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_21720 24890375496394e7c9310a776d92cbbf 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 100 113 2.4E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_21720 24890375496394e7c9310a776d92cbbf 404 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 104 114 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_21720 24890375496394e7c9310a776d92cbbf 404 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 271 281 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_21720 24890375496394e7c9310a776d92cbbf 404 SUPERFAMILY SSF52743 51 330 1.14E-77 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_21720 24890375496394e7c9310a776d92cbbf 404 Pfam PF00082 Subtilase family 61 320 8.0E-41 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_21720 24890375496394e7c9310a776d92cbbf 404 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 66 77 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_21720 24890375496394e7c9310a776d92cbbf 404 Gene3D G3DSA:3.40.50.200 18 333 3.1E-85 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_21720 24890375496394e7c9310a776d92cbbf 404 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 53 394 9.7E-96 T 12-10-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin AFR_14345 8a186aed6f9b158844c94e0b515e4d8d 406 Pfam PF07690 Major Facilitator Superfamily 25 369 4.8E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_14345 8a186aed6f9b158844c94e0b515e4d8d 406 Gene3D G3DSA:1.20.1720.10 21 401 5.3E-89 T 12-10-2018 AFR_14345 8a186aed6f9b158844c94e0b515e4d8d 406 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 22 401 2.5E-71 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 AFR_14345 8a186aed6f9b158844c94e0b515e4d8d 406 SUPERFAMILY SSF103473 20 403 1.02E-58 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_15200 cbf34b981fcaa3ddd35e5311e61830b2 277 SUPERFAMILY SSF52151 3 207 7.32E-31 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_15200 cbf34b981fcaa3ddd35e5311e61830b2 277 Pfam PF01734 Patatin-like phospholipase 5 196 5.5E-16 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFR_15200 cbf34b981fcaa3ddd35e5311e61830b2 277 Gene3D G3DSA:3.40.1090.10 1 71 4.6E-8 T 12-10-2018 AFR_15200 cbf34b981fcaa3ddd35e5311e61830b2 277 Gene3D G3DSA:3.40.1090.10 116 211 8.5E-15 T 12-10-2018 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 SUPERFAMILY SSF55785 326 458 3.14E-9 T 12-10-2018 IPR035965 PAS domain superfamily AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 SUPERFAMILY SSF47384 450 533 8.04E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 SMART SM01079 57 247 1.6E-4 T 12-10-2018 IPR006189 CHASE domain AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 Pfam PF00512 His Kinase A (phospho-acceptor) domain 470 534 6.9E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 SUPERFAMILY SSF55874 535 693 2.49E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 Gene3D G3DSA:3.30.450.20 326 457 1.5E-13 T 12-10-2018 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 Gene3D G3DSA:3.30.565.10 570 703 1.6E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 SMART SM00388 466 538 5.5E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 PRINTS PR00344 Bacterial sensor protein C-terminal signature 655 673 4.9E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 PRINTS PR00344 Bacterial sensor protein C-terminal signature 679 692 4.9E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 PRINTS PR00344 Bacterial sensor protein C-terminal signature 622 636 4.9E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 PRINTS PR00344 Bacterial sensor protein C-terminal signature 640 650 4.9E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 341 466 4.0E-7 T 12-10-2018 IPR000014 PAS domain AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 Gene3D G3DSA:1.10.287.130 458 533 2.0E-10 T 12-10-2018 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 Pfam PF03924 CHASE domain 61 221 1.4E-16 T 12-10-2018 IPR006189 CHASE domain AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 SMART SM00387 582 695 3.2E-39 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 Gene3D G3DSA:3.30.450.350 77 269 1.7E-5 T 12-10-2018 AFR_27030 209f8f1b14f9cbf6177f12d74417403d 746 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 583 694 1.5E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17880 8becc3cdf4674b142f51c01be2a7059d 371 SMART SM00637 276 367 2.0E-37 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_17880 8becc3cdf4674b142f51c01be2a7059d 371 SUPERFAMILY SSF81296 35 228 5.46E-29 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_17880 8becc3cdf4674b142f51c01be2a7059d 371 Pfam PF00553 Cellulose binding domain 276 366 2.9E-25 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_17880 8becc3cdf4674b142f51c01be2a7059d 371 Gene3D G3DSA:2.60.40.290 271 370 8.9E-28 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_17880 8becc3cdf4674b142f51c01be2a7059d 371 SUPERFAMILY SSF49384 270 367 5.86E-28 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_17880 8becc3cdf4674b142f51c01be2a7059d 371 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 35 225 1.2E-31 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal AFR_17880 8becc3cdf4674b142f51c01be2a7059d 371 Gene3D G3DSA:2.70.50.50 35 228 2.0E-61 T 12-10-2018 AFR_37870 b4d22f09125de73403625d31688c89f2 268 Gene3D G3DSA:3.75.10.10 8 265 4.5E-53 T 12-10-2018 AFR_37870 b4d22f09125de73403625d31688c89f2 268 Pfam PF02274 Amidinotransferase 63 266 1.6E-15 T 12-10-2018 AFR_37870 b4d22f09125de73403625d31688c89f2 268 SUPERFAMILY SSF55909 5 267 4.51E-55 T 12-10-2018 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SUPERFAMILY SSF47807 178 291 3.14E-30 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SMART SM00475 8 268 9.2E-127 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 9 177 2.6E-53 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Pfam PF00476 DNA polymerase family A 518 893 1.9E-145 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Gene3D G3DSA:3.30.420.10 331 510 1.3E-32 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Gene3D G3DSA:1.10.150.20 181 253 9.4E-91 T 12-10-2018 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 781 792 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 622 644 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 722 747 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 668 691 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 698 711 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 759 770 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 813 829 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 645 660 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 PRINTS PR00868 DNA-polymerase family A (pol I) signature 843 856 8.8E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Gene3D G3DSA:3.30.70.370 631 892 9.0E-103 T 12-10-2018 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Gene3D G3DSA:1.20.1060.10 511 625 2.0E-32 T 12-10-2018 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 178 272 1.6E-25 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SUPERFAMILY SSF56672 493 893 4.89E-142 T 12-10-2018 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SMART SM00482 653 860 4.4E-114 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SUPERFAMILY SSF53098 312 484 1.77E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SMART SM00474 309 484 8.4E-6 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 TIGRFAM TIGR00593 pola: DNA polymerase I 10 894 3.4E-299 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Gene3D G3DSA:3.40.50.1010 10 284 9.4E-91 T 12-10-2018 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SMART SM00279 180 215 2.4E-8 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 Gene3D G3DSA:1.10.150.20 677 820 9.0E-103 T 12-10-2018 AFR_10430 f083463882f2ed6d40d7fb95c47a4b82 897 SUPERFAMILY SSF88723 6 177 1.53E-52 T 12-10-2018 IPR029060 PIN-like domain superfamily AFR_10205 47bfa5caa1a1fb4065df02aee03e5cef 134 Gene3D G3DSA:3.10.450.40 63 133 5.5E-14 T 12-10-2018 AFR_10205 47bfa5caa1a1fb4065df02aee03e5cef 134 Pfam PF03413 Peptidase propeptide and YPEB domain 70 127 2.4E-8 T 12-10-2018 IPR025711 PepSY domain AFR_22385 0914aa0564acddc803553a23790286b1 249 Gene3D G3DSA:3.40.50.300 12 246 8.3E-65 T 12-10-2018 AFR_22385 0914aa0564acddc803553a23790286b1 249 SUPERFAMILY SSF52540 15 232 8.5E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22385 0914aa0564acddc803553a23790286b1 249 Pfam PF00005 ABC transporter 34 179 6.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_22385 0914aa0564acddc803553a23790286b1 249 SMART SM00382 42 227 1.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 SUPERFAMILY SSF51735 1 191 6.74E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 420 3.0E-26 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 PIRSF PIRSF500134 1 437 1.3E-152 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 295 4.1E-31 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 Gene3D G3DSA:1.20.5.100 202 231 1.1E-13 T 12-10-2018 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 SMART SM00984 320 421 1.7E-37 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 Gene3D G3DSA:3.40.50.720 1 200 7.2E-69 T 12-10-2018 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 416 2.3E-128 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 Gene3D G3DSA:3.40.50.720 233 437 6.1E-65 T 12-10-2018 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 SUPERFAMILY SSF52413 311 431 1.09E-33 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 1.6E-59 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 SUPERFAMILY SSF48179 202 299 3.74E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_22725 0ba39072c56a368f91f37649c6d26e6d 437 PIRSF PIRSF000124 1 436 4.9E-120 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_41555 31b699042fc163a4c676b0e611cb6198 352 Gene3D G3DSA:1.20.150.30 4 131 2.9E-31 T 12-10-2018 AFR_41555 31b699042fc163a4c676b0e611cb6198 352 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 5 345 1.1E-102 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 AFR_41555 31b699042fc163a4c676b0e611cb6198 352 SUPERFAMILY SSF55486 4 344 5.64E-98 T 12-10-2018 AFR_41555 31b699042fc163a4c676b0e611cb6198 352 Pfam PF10103 Zincin-like metallopeptidase 5 341 2.5E-111 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 AFR_41555 31b699042fc163a4c676b0e611cb6198 352 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 5 345 7.2E-132 T 12-10-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated AFR_34555 4bee17d0bfa833f874625ea9128a8ba4 319 Pfam PF01896 DNA primase small subunit 138 260 2.8E-6 T 12-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 AFR_34555 4bee17d0bfa833f874625ea9128a8ba4 319 Gene3D G3DSA:3.90.920.30 24 302 3.6E-88 T 12-10-2018 AFR_34555 4bee17d0bfa833f874625ea9128a8ba4 319 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 17 264 1.3E-70 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain AFR_34555 4bee17d0bfa833f874625ea9128a8ba4 319 SUPERFAMILY SSF56747 115 204 3.05E-5 T 12-10-2018 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 PRINTS PR00297 10kDa chaperonin signature 9 24 1.3E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 PRINTS PR00297 10kDa chaperonin signature 66 78 1.3E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 PRINTS PR00297 10kDa chaperonin signature 31 52 1.3E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 PRINTS PR00297 10kDa chaperonin signature 87 100 1.3E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 Gene3D G3DSA:2.30.33.40 3 102 1.0E-39 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 SUPERFAMILY SSF50129 8 101 5.56E-35 T 12-10-2018 IPR011032 GroES-like superfamily AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 Pfam PF00166 Chaperonin 10 Kd subunit 9 100 2.0E-36 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 SMART SM00883 8 100 1.8E-55 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 Hamap MF_00580 10 kDa chaperonin [groS]. 8 101 26.133 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_04915 ffdf47aeafa8f43c4a6162ea4190e3c4 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 9 33 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 AFR_29015 8ec056cde23e4af65221d3016efa494c 157 Pfam PF13463 Winged helix DNA-binding domain 48 101 1.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29015 8ec056cde23e4af65221d3016efa494c 157 Gene3D G3DSA:1.10.10.10 8 140 1.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29015 8ec056cde23e4af65221d3016efa494c 157 SMART SM00347 26 128 5.6E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29015 8ec056cde23e4af65221d3016efa494c 157 SUPERFAMILY SSF46785 11 138 8.91E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_21575 be11ce06c91a4d5e25b369780a3f047f 365 Pfam PF07730 Histidine kinase 162 227 1.7E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_21575 be11ce06c91a4d5e25b369780a3f047f 365 Gene3D G3DSA:3.30.565.10 234 356 5.1E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21575 be11ce06c91a4d5e25b369780a3f047f 365 SUPERFAMILY SSF55874 240 355 1.19E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 SUPERFAMILY SSF55021 86 162 2.66E-14 T 12-10-2018 AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 PIRSF PIRSF028103 1 121 3.5E-17 T 12-10-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 PIRSF PIRSF028103 84 166 4.1E-9 T 12-10-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 Gene3D G3DSA:3.30.70.260 84 165 8.4E-19 T 12-10-2018 AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 SUPERFAMILY SSF55021 4 69 1.99E-13 T 12-10-2018 AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 Gene3D G3DSA:3.30.70.260 2 76 1.3E-16 T 12-10-2018 AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 Pfam PF13740 ACT domain 4 61 1.9E-10 T 12-10-2018 AFR_41340 44320f1fd43df1f4dc12874b5adbb65a 167 Pfam PF13740 ACT domain 88 158 2.7E-9 T 12-10-2018 AFR_32275 60ea27b0e8386ac95bbe19b014244dcf 268 Pfam PF00005 ABC transporter 23 168 4.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_32275 60ea27b0e8386ac95bbe19b014244dcf 268 Gene3D G3DSA:3.40.50.300 5 257 1.1E-62 T 12-10-2018 AFR_32275 60ea27b0e8386ac95bbe19b014244dcf 268 SMART SM00382 29 225 4.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_32275 60ea27b0e8386ac95bbe19b014244dcf 268 SUPERFAMILY SSF52540 5 229 5.97E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32275 60ea27b0e8386ac95bbe19b014244dcf 268 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_03675 e5934cf6f837c441a85e555261f478a0 683 Pfam PF00246 Zinc carboxypeptidase 394 659 2.9E-36 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_03675 e5934cf6f837c441a85e555261f478a0 683 Gene3D G3DSA:3.40.630.10 377 682 4.3E-55 T 12-10-2018 AFR_03675 e5934cf6f837c441a85e555261f478a0 683 SUPERFAMILY SSF53187 386 675 2.08E-47 T 12-10-2018 AFR_03675 e5934cf6f837c441a85e555261f478a0 683 SMART SM00631 230 646 3.9E-18 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_04845 6b9c310a3596f0c7153ed2f3f4114c51 160 Gene3D G3DSA:3.40.50.300 2 155 3.5E-31 T 12-10-2018 AFR_04845 6b9c310a3596f0c7153ed2f3f4114c51 160 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 13 144 7.1E-22 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFR_04845 6b9c310a3596f0c7153ed2f3f4114c51 160 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 10 138 2.3E-28 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFR_04845 6b9c310a3596f0c7153ed2f3f4114c51 160 SUPERFAMILY SSF52540 24 140 1.34E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31670 d858503084ae18ad873e10004a090df9 517 SMART SM00283 318 517 7.6E-9 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_31670 d858503084ae18ad873e10004a090df9 517 Pfam PF13185 GAF domain 40 158 3.2E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31670 d858503084ae18ad873e10004a090df9 517 Pfam PF13185 GAF domain 210 348 1.9E-14 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31670 d858503084ae18ad873e10004a090df9 517 SUPERFAMILY SSF55781 26 162 9.38E-12 T 12-10-2018 AFR_31670 d858503084ae18ad873e10004a090df9 517 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 379 512 3.7E-30 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_31670 d858503084ae18ad873e10004a090df9 517 Gene3D G3DSA:3.30.450.40 21 196 5.0E-12 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_31670 d858503084ae18ad873e10004a090df9 517 SMART SM00065 211 362 0.0047 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31670 d858503084ae18ad873e10004a090df9 517 SUPERFAMILY SSF55781 198 354 9.16E-15 T 12-10-2018 AFR_31670 d858503084ae18ad873e10004a090df9 517 Gene3D G3DSA:3.30.450.40 208 325 9.9E-19 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_31670 d858503084ae18ad873e10004a090df9 517 SUPERFAMILY SSF58104 324 510 8.37E-43 T 12-10-2018 AFR_31670 d858503084ae18ad873e10004a090df9 517 Gene3D G3DSA:1.10.287.950 326 517 8.7E-38 T 12-10-2018 AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 Pfam PF00082 Subtilase family 151 499 7.0E-37 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 208 218 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 PRINTS PR00723 Subtilisin serine protease family (S8) signature 150 169 7.6E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 PRINTS PR00723 Subtilisin serine protease family (S8) signature 451 467 7.6E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 PRINTS PR00723 Subtilisin serine protease family (S8) signature 204 217 7.6E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 155 166 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 Gene3D G3DSA:3.40.50.200 118 544 1.5E-74 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 452 462 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_41110 b06a23cb027022c5a6c899dcdf12d131 546 SUPERFAMILY SSF52743 133 543 9.3E-62 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_19120 c48fa8e433737baba7b922491333b3c8 686 SUPERFAMILY SSF55073 258 408 4.55E-21 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_19120 c48fa8e433737baba7b922491333b3c8 686 SMART SM00052 422 665 9.3E-12 T 12-10-2018 IPR001633 EAL domain AFR_19120 c48fa8e433737baba7b922491333b3c8 686 Gene3D G3DSA:3.20.20.450 438 676 1.5E-47 T 12-10-2018 IPR035919 EAL domain superfamily AFR_19120 c48fa8e433737baba7b922491333b3c8 686 Gene3D G3DSA:3.30.70.270 238 414 1.9E-29 T 12-10-2018 AFR_19120 c48fa8e433737baba7b922491333b3c8 686 Pfam PF00563 EAL domain 439 658 7.1E-38 T 12-10-2018 IPR001633 EAL domain AFR_19120 c48fa8e433737baba7b922491333b3c8 686 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 250 406 2.2E-18 T 12-10-2018 IPR000160 GGDEF domain AFR_19120 c48fa8e433737baba7b922491333b3c8 686 Pfam PF00990 Diguanylate cyclase, GGDEF domain 252 406 3.6E-23 T 12-10-2018 IPR000160 GGDEF domain AFR_19120 c48fa8e433737baba7b922491333b3c8 686 SUPERFAMILY SSF141868 439 673 2.48E-38 T 12-10-2018 IPR035919 EAL domain superfamily AFR_19120 c48fa8e433737baba7b922491333b3c8 686 SMART SM00267 241 414 3.7E-24 T 12-10-2018 IPR000160 GGDEF domain AFR_29230 3fb619fb4327f5986de12594d6803578 73 SUPERFAMILY SSF160582 1 69 1.06E-29 T 12-10-2018 IPR038020 MbtH-like domain superfamily AFR_29230 3fb619fb4327f5986de12594d6803578 73 Gene3D G3DSA:3.90.820.10 1 72 1.0E-31 T 12-10-2018 AFR_29230 3fb619fb4327f5986de12594d6803578 73 SMART SM00923 3 53 1.1E-29 T 12-10-2018 IPR005153 MbtH-like domain AFR_29230 3fb619fb4327f5986de12594d6803578 73 Pfam PF03621 MbtH-like protein 1 53 1.4E-27 T 12-10-2018 IPR005153 MbtH-like domain AFR_23140 edb967536b3a36c8761912b7e8412ca7 379 Gene3D G3DSA:3.40.50.1820 32 367 1.6E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23140 edb967536b3a36c8761912b7e8412ca7 379 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 37 162 1.0E-12 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 AFR_23140 edb967536b3a36c8761912b7e8412ca7 379 SUPERFAMILY SSF53474 41 317 1.43E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 433 3.9E-118 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 183 4.3E-52 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 212 305 1.6E-32 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 336 436 8.4E-24 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 Gene3D G3DSA:1.20.5.100 211 240 9.7E-14 T 12-10-2018 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 SUPERFAMILY SSF52413 329 447 3.53E-31 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 SMART SM00984 336 437 6.4E-37 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 SUPERFAMILY SSF48179 211 310 1.97E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 Gene3D G3DSA:3.40.50.720 3 207 9.4E-65 T 12-10-2018 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 SUPERFAMILY SSF51735 7 191 1.97E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 PIRSF PIRSF500134 4 455 4.5E-144 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 Gene3D G3DSA:3.40.50.720 242 462 4.2E-59 T 12-10-2018 AFR_16505 4f0fa89422e687ab8012a6e33d4bc4e2 480 PIRSF PIRSF000124 5 452 1.4E-115 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_30055 770abe5e95a3e898fd54696ff24397e9 201 SUPERFAMILY SSF50486 13 197 2.98E-54 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 AFR_30055 770abe5e95a3e898fd54696ff24397e9 201 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 1 191 29.111 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFR_30055 770abe5e95a3e898fd54696ff24397e9 201 Gene3D G3DSA:3.10.300.10 2 200 6.1E-59 T 12-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFR_30055 770abe5e95a3e898fd54696ff24397e9 201 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 15 191 3.9E-48 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFR_30055 770abe5e95a3e898fd54696ff24397e9 201 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 13 188 2.1E-59 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFR_33130 06b82db93d25c3f9238d26bff0c0b61a 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 293 4.5E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_33130 06b82db93d25c3f9238d26bff0c0b61a 304 SUPERFAMILY SSF161098 68 293 4.58E-59 T 12-10-2018 IPR035906 MetI-like superfamily AFR_33130 06b82db93d25c3f9238d26bff0c0b61a 304 Gene3D G3DSA:1.10.3720.10 64 303 2.2E-67 T 12-10-2018 IPR035906 MetI-like superfamily AFR_07010 bfc98ee1b939ae9b895089ba1fd6bbd6 160 SUPERFAMILY SSF46785 36 148 2.5E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_07010 bfc98ee1b939ae9b895089ba1fd6bbd6 160 Gene3D G3DSA:1.10.10.10 12 147 6.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07010 bfc98ee1b939ae9b895089ba1fd6bbd6 160 SMART SM00347 33 133 5.1E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_07010 bfc98ee1b939ae9b895089ba1fd6bbd6 160 Pfam PF01047 MarR family 40 98 1.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_01305 eb29d48aa6d2ce27448a5b3c07adb710 266 Gene3D G3DSA:3.20.20.30 133 264 6.7E-12 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_01305 eb29d48aa6d2ce27448a5b3c07adb710 266 Pfam PF00296 Luciferase-like monooxygenase 10 130 2.6E-23 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_01305 eb29d48aa6d2ce27448a5b3c07adb710 266 Pfam PF00296 Luciferase-like monooxygenase 126 176 1.4E-5 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_01305 eb29d48aa6d2ce27448a5b3c07adb710 266 SUPERFAMILY SSF51679 4 263 8.24E-42 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_01305 eb29d48aa6d2ce27448a5b3c07adb710 266 Gene3D G3DSA:3.20.20.30 3 132 2.4E-29 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_39615 7d7c007fb1fe0cde3799f0c18679e5d9 312 Pfam PF03631 Virulence factor BrkB 47 283 4.4E-31 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 Hamap MF_01227 CTP synthase [pyrG]. 8 549 50.081 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 SUPERFAMILY SSF52317 300 549 7.37E-76 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 TIGRFAM TIGR00337 PyrG: CTP synthase 8 544 2.9E-231 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 Pfam PF00117 Glutamine amidotransferase class-I 312 544 1.8E-47 T 12-10-2018 IPR017926 Glutamine amidotransferase AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 SUPERFAMILY SSF52540 8 277 7.21E-118 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 Gene3D G3DSA:3.40.50.300 2 296 1.4E-132 T 12-10-2018 AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 Gene3D G3DSA:3.40.50.880 297 551 6.3E-101 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_29895 111f453fa935ebcfd8a57ff8eb0e1d3b 572 Pfam PF06418 CTP synthase N-terminus 9 277 2.9E-121 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFR_39135 734413dd1ba1fbd1941790a6c355a408 197 SUPERFAMILY SSF55729 60 168 1.92E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_39135 734413dd1ba1fbd1941790a6c355a408 197 Pfam PF00583 Acetyltransferase (GNAT) family 67 162 1.9E-11 T 12-10-2018 IPR000182 GNAT domain AFR_39135 734413dd1ba1fbd1941790a6c355a408 197 Gene3D G3DSA:3.40.630.30 1 168 2.9E-19 T 12-10-2018 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 Gene3D G3DSA:3.30.930.10 2 281 6.2E-94 T 12-10-2018 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 102 266 4.5E-15 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 468 39.485 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 7 457 2.5E-147 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 SUPERFAMILY SSF52954 276 398 2.11E-27 T 12-10-2018 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 Gene3D G3DSA:3.40.50.800 282 397 2.3E-25 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 Pfam PF03129 Anticodon binding domain 290 376 2.6E-13 T 12-10-2018 IPR004154 Anticodon-binding AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 SMART SM00946 407 468 0.0075 T 12-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.2E-6 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.2E-6 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 PRINTS PR01046 Prolyl-tRNA synthetase signature 63 81 2.2E-6 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 PRINTS PR01046 Prolyl-tRNA synthetase signature 143 154 2.2E-6 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFR_36345 821ee6c8d24c0cb371a329649a7c58c0 468 SUPERFAMILY SSF55681 10 275 2.84E-71 T 12-10-2018 AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SUPERFAMILY SSF51126 72 690 4.94E-10 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SUPERFAMILY SSF50370 666 792 1.19E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29180 551715a63d657bcc6c32a106782aeb40 793 Gene3D G3DSA:2.160.20.10 27 254 5.4E-13 T 12-10-2018 IPR012334 Pectin lyase fold AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SMART SM00458 664 793 3.7E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29180 551715a63d657bcc6c32a106782aeb40 793 Gene3D G3DSA:2.80.10.50 668 792 3.8E-39 T 12-10-2018 AFR_29180 551715a63d657bcc6c32a106782aeb40 793 Pfam PF00652 Ricin-type beta-trefoil lectin domain 667 790 8.9E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SMART SM00710 410 432 73.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SMART SM00710 447 472 530.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SMART SM00710 375 397 1200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SMART SM00710 304 339 960.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SMART SM00710 475 497 430.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_29180 551715a63d657bcc6c32a106782aeb40 793 SMART SM00710 528 555 2200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 PIRSF PIRSF001112 1 402 2.2E-130 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 Gene3D G3DSA:3.40.50.1820 10 402 7.3E-123 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 SUPERFAMILY SSF53474 5 398 5.68E-89 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 Pfam PF06441 Epoxide hydrolase N terminus 13 118 3.5E-31 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 PRINTS PR00412 Epoxide hydrolase signature 138 153 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 PRINTS PR00412 Epoxide hydrolase signature 109 127 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 PRINTS PR00412 Epoxide hydrolase signature 374 396 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23055 306f5a28596ee477ab121aaf1badcc05 405 PRINTS PR00412 Epoxide hydrolase signature 342 358 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_29735 37a8c301a0165ea849eb5642fe02d0ad 197 SUPERFAMILY SSF48498 88 191 5.82E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_29735 37a8c301a0165ea849eb5642fe02d0ad 197 SUPERFAMILY SSF46689 8 73 4.58E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29735 37a8c301a0165ea849eb5642fe02d0ad 197 Gene3D G3DSA:1.10.357.10 2 196 2.5E-30 T 12-10-2018 AFR_29735 37a8c301a0165ea849eb5642fe02d0ad 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 5.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 Gene3D G3DSA:3.30.70.2740 376 454 6.7E-7 T 12-10-2018 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 Gene3D G3DSA:3.30.465.40 15 185 2.2E-46 T 12-10-2018 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 SUPERFAMILY SSF55103 255 498 1.29E-55 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 593 604 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 Pfam PF02913 FAD linked oxidases, C-terminal domain 254 492 1.9E-51 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 Pfam PF01565 FAD binding domain 33 171 1.1E-40 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 Pfam PF13183 4Fe-4S dicluster domain 530 607 2.9E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 SUPERFAMILY SSF56176 15 249 2.38E-54 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 Gene3D G3DSA:1.10.45.10 455 495 1.1E-5 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 SUPERFAMILY SSF46548 528 611 1.05E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_17915 99ce17167dae2dc1abe7e795111ae955 925 Pfam PF02754 Cysteine-rich domain 707 782 8.5E-6 T 12-10-2018 IPR004017 Cysteine-rich domain AFR_23180 67c236ee8ef55b616da8c38c2efb7440 294 Gene3D G3DSA:1.10.260.40 30 100 7.0E-10 T 12-10-2018 AFR_23180 67c236ee8ef55b616da8c38c2efb7440 294 Gene3D G3DSA:3.30.450.180 111 293 2.3E-13 T 12-10-2018 AFR_23180 67c236ee8ef55b616da8c38c2efb7440 294 SMART SM00530 14 86 2.6E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_23180 67c236ee8ef55b616da8c38c2efb7440 294 Pfam PF13560 Helix-turn-helix domain 10 89 2.2E-17 T 12-10-2018 AFR_23180 67c236ee8ef55b616da8c38c2efb7440 294 SUPERFAMILY SSF47413 34 85 8.44E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_22165 c4d190e9d21b7b427a0d48f143f54567 190 Pfam PF08281 Sigma-70, region 4 121 172 1.3E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_22165 c4d190e9d21b7b427a0d48f143f54567 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 174 7.4E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_22165 c4d190e9d21b7b427a0d48f143f54567 190 SUPERFAMILY SSF88659 112 175 3.05E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_22165 c4d190e9d21b7b427a0d48f143f54567 190 Gene3D G3DSA:1.10.10.10 115 180 6.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22165 c4d190e9d21b7b427a0d48f143f54567 190 SUPERFAMILY SSF88946 5 107 1.18E-19 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_22165 c4d190e9d21b7b427a0d48f143f54567 190 Gene3D G3DSA:1.10.1740.10 4 84 1.2E-17 T 12-10-2018 AFR_22165 c4d190e9d21b7b427a0d48f143f54567 190 Pfam PF04542 Sigma-70 region 2 20 88 2.1E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 8.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 8.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 8.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 8.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 Gene3D G3DSA:3.40.50.720 4 257 7.6E-50 T 12-10-2018 AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 5.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 5.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 5.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 Pfam PF00106 short chain dehydrogenase 3 188 9.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29275 2acd10206bcbe7b2bca7bc6ba844484c 282 SUPERFAMILY SSF51735 3 226 7.45E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38985 d935ee6d62936c572decaad679c61de4 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 3.5E-16 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_38985 d935ee6d62936c572decaad679c61de4 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 5.9E-47 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_38985 d935ee6d62936c572decaad679c61de4 390 Gene3D G3DSA:1.20.140.10 238 383 2.7E-51 T 12-10-2018 AFR_38985 d935ee6d62936c572decaad679c61de4 390 PIRSF PIRSF016578 133 201 0.018 T 12-10-2018 AFR_38985 d935ee6d62936c572decaad679c61de4 390 PIRSF PIRSF016578 8 88 1.9 T 12-10-2018 AFR_38985 d935ee6d62936c572decaad679c61de4 390 PIRSF PIRSF016578 240 380 4.1E-13 T 12-10-2018 AFR_38985 d935ee6d62936c572decaad679c61de4 390 Gene3D G3DSA:1.10.540.10 1 122 1.4E-21 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_38985 d935ee6d62936c572decaad679c61de4 390 SUPERFAMILY SSF56645 2 242 5.89E-62 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_38985 d935ee6d62936c572decaad679c61de4 390 SUPERFAMILY SSF47203 228 382 1.26E-53 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_38985 d935ee6d62936c572decaad679c61de4 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 196 7.6E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_38985 d935ee6d62936c572decaad679c61de4 390 Gene3D G3DSA:2.40.110.10 124 237 4.4E-36 T 12-10-2018 AFR_09865 dcc07410cd69b033f3b337a654941901 269 SUPERFAMILY SSF51735 2 241 1.2E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_09865 dcc07410cd69b033f3b337a654941901 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09865 dcc07410cd69b033f3b337a654941901 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09865 dcc07410cd69b033f3b337a654941901 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09865 dcc07410cd69b033f3b337a654941901 269 Gene3D G3DSA:3.40.50.720 2 268 2.2E-62 T 12-10-2018 AFR_09865 dcc07410cd69b033f3b337a654941901 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09865 dcc07410cd69b033f3b337a654941901 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09865 dcc07410cd69b033f3b337a654941901 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09865 dcc07410cd69b033f3b337a654941901 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 5.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09865 dcc07410cd69b033f3b337a654941901 269 Pfam PF00106 short chain dehydrogenase 4 195 4.9E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Gene3D G3DSA:3.30.365.10 543 679 6.5E-55 T 12-10-2018 AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Gene3D G3DSA:3.30.365.10 156 377 1.0E-60 T 12-10-2018 AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 SUPERFAMILY SSF54665 8 129 1.83E-25 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 SMART SM01008 23 127 1.3E-18 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 153 522 1.9E-87 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 537 627 6.6E-25 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Gene3D G3DSA:3.30.365.10 180 272 1.0E-60 T 12-10-2018 AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 SUPERFAMILY SSF56003 156 686 5.1E-154 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 126 1.5E-13 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Gene3D G3DSA:3.30.365.20 402 524 5.3E-19 T 12-10-2018 AFR_34790 72e2ccd022e097d576592ef1fbc8da67 688 Gene3D G3DSA:3.90.1170.50 1 127 2.5E-20 T 12-10-2018 AFR_13585 d79240556c5dd130a0b1e66c222c746d 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13585 d79240556c5dd130a0b1e66c222c746d 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13585 d79240556c5dd130a0b1e66c222c746d 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_13585 d79240556c5dd130a0b1e66c222c746d 188 SUPERFAMILY SSF46689 3 78 4.0E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13585 d79240556c5dd130a0b1e66c222c746d 188 Gene3D G3DSA:1.10.357.10 1 188 1.8E-44 T 12-10-2018 AFR_13585 d79240556c5dd130a0b1e66c222c746d 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.6E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 SUPERFAMILY SSF51735 6 229 2.58E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 184 0.0067 T 12-10-2018 AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 Pfam PF00106 short chain dehydrogenase 7 191 4.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.0E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.0E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.0E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.0E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.0E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07075 2bccd6cc6ea346eb997e19f7c0ec0c33 230 Gene3D G3DSA:3.40.50.720 3 229 1.1E-56 T 12-10-2018 AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 61 580 1.7E-88 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 Pfam PF03023 MviN-like protein 87 535 4.9E-80 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 PRINTS PR01806 Virulence factor MviN signature 327 353 2.7E-12 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 PRINTS PR01806 Virulence factor MviN signature 481 498 2.7E-12 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 PRINTS PR01806 Virulence factor MviN signature 107 123 2.7E-12 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 PRINTS PR01806 Virulence factor MviN signature 210 231 2.7E-12 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 PRINTS PR01806 Virulence factor MviN signature 425 444 2.7E-12 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_42910 63c33c4b2b65d863fe8ba040af044b55 589 PRINTS PR01806 Virulence factor MviN signature 186 210 2.7E-12 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_18430 b373fa3c0ff87c4e525271ba55579668 383 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFR_18430 b373fa3c0ff87c4e525271ba55579668 383 Pfam PF01266 FAD dependent oxidoreductase 5 360 2.8E-45 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_18430 b373fa3c0ff87c4e525271ba55579668 383 SUPERFAMILY SSF51905 4 378 1.34E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18430 b373fa3c0ff87c4e525271ba55579668 383 Gene3D G3DSA:3.30.9.10 60 325 1.3E-114 T 12-10-2018 AFR_18430 b373fa3c0ff87c4e525271ba55579668 383 Gene3D G3DSA:3.50.50.60 5 374 1.3E-114 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18430 b373fa3c0ff87c4e525271ba55579668 383 SUPERFAMILY SSF54373 217 321 2.39E-21 T 12-10-2018 AFR_26555 51992c66d7cd7cb326655d08ab4f382d 442 Gene3D G3DSA:3.30.565.10 319 441 1.9E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26555 51992c66d7cd7cb326655d08ab4f382d 442 SMART SM00387 352 442 1.9E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_26555 51992c66d7cd7cb326655d08ab4f382d 442 SUPERFAMILY SSF55874 328 440 1.2E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26555 51992c66d7cd7cb326655d08ab4f382d 442 Pfam PF13796 Putative sensor 68 222 3.8E-17 T 12-10-2018 IPR025828 Putative sensor domain AFR_26555 51992c66d7cd7cb326655d08ab4f382d 442 Pfam PF07730 Histidine kinase 250 320 3.8E-8 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Pfam PF13229 Right handed beta helix region 118 254 1.1E-10 T 12-10-2018 IPR039448 Right handed beta helix domain AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Pfam PF13229 Right handed beta helix region 374 494 1.0E-5 T 12-10-2018 IPR039448 Right handed beta helix domain AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Gene3D G3DSA:3.40.50.300 825 1007 1.9E-14 T 12-10-2018 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Gene3D G3DSA:3.40.50.300 528 724 1.4E-55 T 12-10-2018 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 674 686 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 695 712 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 589 604 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 549 563 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 712 731 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 641 660 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 769 781 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 PRINTS PR00819 CbxX/CfqX superfamily signature 627 641 4.0E-51 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SUPERFAMILY SSF51126 3 205 1.54E-24 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00382 876 1074 0.84 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00382 586 727 5.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 591 724 5.8E-16 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SUPERFAMILY SSF52540 854 1048 7.76E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SUPERFAMILY SSF51126 308 494 9.43E-12 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 277 298 550.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 116 138 140.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 231 253 2800.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 139 161 1100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 254 276 5700.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 457 479 19.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 69 93 10000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 368 390 4300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 162 184 2800.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SMART SM00710 411 433 430.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Gene3D G3DSA:2.160.20.10 12 258 3.5E-17 T 12-10-2018 IPR012334 Pectin lyase fold AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SUPERFAMILY SSF51126 215 389 1.39E-7 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Gene3D G3DSA:1.10.8.60 725 812 2.7E-15 T 12-10-2018 AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 Gene3D G3DSA:2.160.20.10 308 503 2.2E-7 T 12-10-2018 IPR012334 Pectin lyase fold AFR_02565 b779853177b9110c3c2c7e5c858fa470 1097 SUPERFAMILY SSF52540 553 791 2.1E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03300 aa7aa60ef239a8cb08e2dc986933cb75 473 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 10 305 3.0E-7 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 AFR_03300 aa7aa60ef239a8cb08e2dc986933cb75 473 SUPERFAMILY SSF50443 330 473 1.75E-21 T 12-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal AFR_03300 aa7aa60ef239a8cb08e2dc986933cb75 473 SUPERFAMILY SSF53743 10 332 1.44E-70 T 12-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 AFR_03300 aa7aa60ef239a8cb08e2dc986933cb75 473 Gene3D G3DSA:3.40.50.10940 29 180 2.9E-5 T 12-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 AFR_03300 aa7aa60ef239a8cb08e2dc986933cb75 473 Pfam PF02610 L-arabinose isomerase 31 342 3.7E-14 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 AFR_21505 c305ca468cf9b9489d21ac5d383a0e41 159 SUPERFAMILY SSF143744 17 156 2.62E-25 T 12-10-2018 IPR038084 GlcG-like domain superfamily AFR_21505 c305ca468cf9b9489d21ac5d383a0e41 159 Pfam PF03928 Haem-degrading 25 153 1.8E-31 T 12-10-2018 IPR005624 Haem-degrading AFR_21505 c305ca468cf9b9489d21ac5d383a0e41 159 PIRSF PIRSF008757 1 159 2.8E-62 T 12-10-2018 IPR010371 Uncharacterised protein family UPF0303 AFR_21505 c305ca468cf9b9489d21ac5d383a0e41 159 Hamap MF_00761 UPF0303 protein . 6 158 34.013 T 12-10-2018 IPR010371 Uncharacterised protein family UPF0303 AFR_21505 c305ca468cf9b9489d21ac5d383a0e41 159 Gene3D G3DSA:3.30.450.150 2 159 1.3E-54 T 12-10-2018 IPR038084 GlcG-like domain superfamily AFR_13910 72e0a1941a8e4951d637a41bdfbe5064 294 SUPERFAMILY SSF56112 16 267 1.28E-32 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_13910 72e0a1941a8e4951d637a41bdfbe5064 294 Pfam PF03881 Fructosamine kinase 25 278 3.6E-39 T 12-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 AFR_13910 72e0a1941a8e4951d637a41bdfbe5064 294 PIRSF PIRSF006221 10 290 9.1E-40 T 12-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 AFR_13910 72e0a1941a8e4951d637a41bdfbe5064 294 Gene3D G3DSA:3.90.1200.10 98 288 1.5E-40 T 12-10-2018 AFR_13910 72e0a1941a8e4951d637a41bdfbe5064 294 Gene3D G3DSA:3.30.200.20 9 91 4.1E-15 T 12-10-2018 AFR_24870 2b2d3f7861e3e8f4b166c5b033153fea 1274 Gene3D G3DSA:1.20.1640.10 157 346 1.0E-6 T 12-10-2018 AFR_24870 2b2d3f7861e3e8f4b166c5b033153fea 1274 SUPERFAMILY SSF82866 147 343 2.22E-30 T 12-10-2018 AFR_24870 2b2d3f7861e3e8f4b166c5b033153fea 1274 SUPERFAMILY SSF82866 469 700 8.63E-25 T 12-10-2018 AFR_24870 2b2d3f7861e3e8f4b166c5b033153fea 1274 Pfam PF03176 MMPL family 55 376 5.9E-45 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_24870 2b2d3f7861e3e8f4b166c5b033153fea 1274 Pfam PF03176 MMPL family 469 706 7.7E-26 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_18720 c17c201c68d655dd9a4e81ad0dafbc30 283 Gene3D G3DSA:3.40.50.1820 3 282 9.0E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18720 c17c201c68d655dd9a4e81ad0dafbc30 283 Pfam PF00561 alpha/beta hydrolase fold 23 264 2.8E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18720 c17c201c68d655dd9a4e81ad0dafbc30 283 SUPERFAMILY SSF53474 4 276 7.65E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18720 c17c201c68d655dd9a4e81ad0dafbc30 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.0E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18720 c17c201c68d655dd9a4e81ad0dafbc30 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 1.0E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18720 c17c201c68d655dd9a4e81ad0dafbc30 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 1.0E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18720 c17c201c68d655dd9a4e81ad0dafbc30 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.0E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15760 c57739b2c39b3549c22d55cbe7b6b833 313 Pfam PF01636 Phosphotransferase enzyme family 51 255 1.9E-25 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_15760 c57739b2c39b3549c22d55cbe7b6b833 313 SUPERFAMILY SSF56112 17 272 4.23E-31 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_15760 c57739b2c39b3549c22d55cbe7b6b833 313 Gene3D G3DSA:3.90.1200.10 118 286 1.3E-7 T 12-10-2018 AFR_08705 8d3030fd30adaa8adfafdc782faf61ab 361 Gene3D G3DSA:1.10.10.2840 233 359 2.2E-41 T 12-10-2018 AFR_08705 8d3030fd30adaa8adfafdc782faf61ab 361 Pfam PF13556 PucR C-terminal helix-turn-helix domain 296 354 2.2E-21 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFR_16095 24c44d62d79b748443af14f5d426c0b0 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.7E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_16095 24c44d62d79b748443af14f5d426c0b0 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.7E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_16095 24c44d62d79b748443af14f5d426c0b0 114 SMART SM00418 8 85 9.8E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_16095 24c44d62d79b748443af14f5d426c0b0 114 Gene3D G3DSA:1.10.10.10 2 109 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16095 24c44d62d79b748443af14f5d426c0b0 114 Pfam PF12840 Helix-turn-helix domain 8 61 2.2E-15 T 12-10-2018 AFR_16095 24c44d62d79b748443af14f5d426c0b0 114 SUPERFAMILY SSF46785 6 99 9.31E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13945 a147e7062db19c52b498aec20598056a 473 Pfam PF00082 Subtilase family 43 309 1.6E-39 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_13945 a147e7062db19c52b498aec20598056a 473 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 48 59 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_13945 a147e7062db19c52b498aec20598056a 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 276 292 3.6E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_13945 a147e7062db19c52b498aec20598056a 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 85 98 3.6E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_13945 a147e7062db19c52b498aec20598056a 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 43 62 3.6E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_13945 a147e7062db19c52b498aec20598056a 473 SUPERFAMILY SSF52743 30 315 1.57E-58 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_13945 a147e7062db19c52b498aec20598056a 473 Gene3D G3DSA:3.40.50.200 17 333 1.4E-64 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_19145 4f319cdb8e0782462fb53c4359e8d5a2 360 Gene3D G3DSA:3.20.20.100 5 332 7.4E-107 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_19145 4f319cdb8e0782462fb53c4359e8d5a2 360 SUPERFAMILY SSF51430 6 319 1.19E-90 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_19145 4f319cdb8e0782462fb53c4359e8d5a2 360 Pfam PF00248 Aldo/keto reductase family 20 317 2.7E-64 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_05930 8e2734b0ccb7703177d3eb97813fb41a 216 Gene3D G3DSA:1.20.120.530 75 208 5.7E-11 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_05930 8e2734b0ccb7703177d3eb97813fb41a 216 SUPERFAMILY SSF46785 7 75 1.55E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_05930 8e2734b0ccb7703177d3eb97813fb41a 216 Gene3D G3DSA:1.10.10.10 8 72 2.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05930 8e2734b0ccb7703177d3eb97813fb41a 216 Pfam PF07729 FCD domain 81 196 1.9E-12 T 12-10-2018 IPR011711 GntR, C-terminal AFR_05930 8e2734b0ccb7703177d3eb97813fb41a 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 67 1.2E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_05930 8e2734b0ccb7703177d3eb97813fb41a 216 SMART SM00345 13 71 2.4E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_05930 8e2734b0ccb7703177d3eb97813fb41a 216 SUPERFAMILY SSF48008 78 207 4.97E-12 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_25470 3c2c544002adb1faf127f9d48708249a 426 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 412 1.8E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_20510 5a0464326658bb2a5a604754f8c27668 402 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 207 238 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 AFR_20510 5a0464326658bb2a5a604754f8c27668 402 SUPERFAMILY SSF54826 9 112 1.93E-31 T 12-10-2018 AFR_20510 5a0464326658bb2a5a604754f8c27668 402 Gene3D G3DSA:3.20.20.120 105 366 2.9E-160 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_20510 5a0464326658bb2a5a604754f8c27668 402 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 3.8E-31 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFR_20510 5a0464326658bb2a5a604754f8c27668 402 Gene3D G3DSA:3.30.390.10 6 398 2.9E-160 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFR_20510 5a0464326658bb2a5a604754f8c27668 402 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 AFR_20510 5a0464326658bb2a5a604754f8c27668 402 SUPERFAMILY SSF51604 98 385 2.1E-76 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_20510 5a0464326658bb2a5a604754f8c27668 402 SMART SM00922 128 257 2.0E-20 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFR_20510 5a0464326658bb2a5a604754f8c27668 402 Pfam PF13378 Enolase C-terminal domain-like 193 377 1.5E-45 T 12-10-2018 IPR029065 Enolase C-terminal domain-like AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 SMART SM00421 147 204 9.5E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 SMART SM00448 2 115 6.4E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 SUPERFAMILY SSF46894 132 206 1.63E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 Gene3D G3DSA:3.40.50.12740 2 207 3.4E-63 T 12-10-2018 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 Pfam PF00072 Response regulator receiver domain 4 116 2.1E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 SUPERFAMILY SSF52172 1 134 9.82E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 5.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 5.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 5.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22175 9704dcf3ff9e6c57c2fbc5d5305ad8c7 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 6.6E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 PIRSF PIRSF036625 1 237 3.2E-59 T 12-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 SUPERFAMILY SSF52172 159 229 1.94E-9 T 12-10-2018 IPR011006 CheY-like superfamily AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 SMART SM00065 25 172 1.8E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 Pfam PF03861 ANTAR domain 177 229 6.9E-22 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 Gene3D G3DSA:3.30.450.40 10 170 4.4E-21 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 Pfam PF13185 GAF domain 24 162 9.9E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 SUPERFAMILY SSF55781 25 174 2.4E-20 T 12-10-2018 AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 Gene3D G3DSA:1.10.10.10 176 235 1.7E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14655 7eed624114994993b788f12dcaa3d4e2 238 SMART SM01012 174 229 1.4E-23 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 Gene3D G3DSA:3.90.105.10 30 165 2.1E-80 T 12-10-2018 AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 Pfam PF03453 MoeA N-terminal region (domain I and II) 12 158 2.3E-35 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 SUPERFAMILY SSF63882 7 167 4.06E-38 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 SUPERFAMILY SSF63867 317 373 3.11E-5 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 Pfam PF00994 Probable molybdopterin binding domain 173 305 1.5E-17 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 Gene3D G3DSA:2.40.340.10 315 370 2.1E-80 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 SUPERFAMILY SSF53218 167 310 3.53E-24 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 Gene3D G3DSA:2.170.190.11 51 132 2.1E-80 T 12-10-2018 AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 Gene3D G3DSA:3.40.980.10 166 314 2.1E-80 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 SMART SM00852 171 307 1.4E-22 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_22745 6392e5d866eee1758ddd9a414568a75b 387 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 241 275 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 Gene3D G3DSA:3.40.50.620 150 286 5.2E-20 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 SUPERFAMILY SSF52402 152 286 8.29E-21 T 12-10-2018 AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 Gene3D G3DSA:3.40.50.620 3 139 2.5E-19 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 SUPERFAMILY SSF52402 4 140 2.43E-22 T 12-10-2018 AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 PRINTS PR01438 Universal stress protein signature 245 257 5.4E-10 T 12-10-2018 IPR006015 Universal stress protein A AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 PRINTS PR01438 Universal stress protein signature 2 20 5.4E-10 T 12-10-2018 IPR006015 Universal stress protein A AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 PRINTS PR01438 Universal stress protein signature 263 285 5.4E-10 T 12-10-2018 IPR006015 Universal stress protein A AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 Pfam PF00582 Universal stress protein family 5 139 3.2E-17 T 12-10-2018 IPR006016 UspA AFR_24965 5f16d591eb3e3bfacc51abdf502ca935 288 Pfam PF00582 Universal stress protein family 152 285 2.8E-18 T 12-10-2018 IPR006016 UspA AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 SUPERFAMILY SSF46785 1 99 2.99E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 SUPERFAMILY SSF53850 78 279 9.42E-34 T 12-10-2018 AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 Gene3D G3DSA:1.10.10.10 1 80 1.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 Gene3D G3DSA:3.40.190.10 150 253 1.1E-50 T 12-10-2018 AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 Gene3D G3DSA:3.40.190.10 81 270 1.1E-50 T 12-10-2018 AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 28 4.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 4.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 7 18 4.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 Pfam PF03466 LysR substrate binding domain 77 273 3.3E-38 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_37665 a0b27ea69b6536bbbdd95f3619db3dec 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 51 1.2E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23020 f934a720affe48442a87a797a3146572 576 Gene3D G3DSA:2.40.33.20 1 215 1.9E-64 T 12-10-2018 AFR_23020 f934a720affe48442a87a797a3146572 576 SUPERFAMILY SSF52343 339 467 1.83E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_23020 f934a720affe48442a87a797a3146572 576 Pfam PF03475 3-alpha domain 171 209 4.6E-11 T 12-10-2018 IPR005163 3-alpha domain AFR_23020 f934a720affe48442a87a797a3146572 576 SUPERFAMILY SSF54292 458 576 9.39E-17 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_23020 f934a720affe48442a87a797a3146572 576 Gene3D G3DSA:3.10.20.30 490 576 4.5E-12 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_23020 f934a720affe48442a87a797a3146572 576 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 503 569 1.3E-5 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_23020 f934a720affe48442a87a797a3146572 576 Gene3D G3DSA:3.40.50.80 336 472 6.4E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_23020 f934a720affe48442a87a797a3146572 576 Pfam PF03473 MOSC domain 52 161 5.1E-17 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 AFR_23020 f934a720affe48442a87a797a3146572 576 SUPERFAMILY SSF63380 231 334 1.89E-24 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_23020 f934a720affe48442a87a797a3146572 576 Gene3D G3DSA:2.40.30.10 231 335 1.1E-25 T 12-10-2018 AFR_23020 f934a720affe48442a87a797a3146572 576 PRINTS PR00409 Phthalate dioxygenase reductase family signature 322 336 2.8E-9 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFR_23020 f934a720affe48442a87a797a3146572 576 PRINTS PR00409 Phthalate dioxygenase reductase family signature 344 363 2.8E-9 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFR_23020 f934a720affe48442a87a797a3146572 576 PRINTS PR00409 Phthalate dioxygenase reductase family signature 259 269 2.8E-9 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFR_23020 f934a720affe48442a87a797a3146572 576 Pfam PF00175 Oxidoreductase NAD-binding domain 345 448 2.1E-11 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_23020 f934a720affe48442a87a797a3146572 576 SUPERFAMILY SSF50800 1 210 2.09E-60 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 Gene3D G3DSA:1.10.10.10 779 859 2.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 SUPERFAMILY SSF46894 794 856 1.22E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 834 846 1.4E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 804 818 1.4E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 818 834 1.4E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 ProSitePatterns PS00622 LuxR-type HTH domain signature. 818 845 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 Pfam PF00196 Bacterial regulatory proteins, luxR family 803 855 2.1E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 SMART SM00421 801 858 9.0E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06320 13868de468fa8a1b1da65fe223cef8be 863 SUPERFAMILY SSF52540 5 211 2.0E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 Gene3D G3DSA:2.40.10.10 241 334 2.9E-66 T 12-10-2018 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 Gene3D G3DSA:2.40.10.10 168 344 2.9E-66 T 12-10-2018 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 Pfam PF02983 Alpha-lytic protease prodomain 94 146 1.8E-10 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 SUPERFAMILY SSF50494 172 341 3.81E-32 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 PIRSF PIRSF001134 21 347 2.4E-108 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 195 200 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 193 207 5.1E-47 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 288 311 5.1E-47 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 269 286 5.1E-47 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 248 268 5.1E-47 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 312 326 5.1E-47 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_32720 7e5edf617ce87fea612842c83e4fa19f 347 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 297 308 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site AFR_22150 2da00caa720cb59b0940417d80f7a5a8 220 SUPERFAMILY SSF69593 14 215 4.32E-46 T 12-10-2018 AFR_22150 2da00caa720cb59b0940417d80f7a5a8 220 Pfam PF01553 Acyltransferase 20 150 4.3E-21 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_22150 2da00caa720cb59b0940417d80f7a5a8 220 SMART SM00563 34 153 1.2E-27 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_13840 ea22b0e14e8fa9740d504b2db9be9fb8 403 Pfam PF07690 Major Facilitator Superfamily 15 268 1.2E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_13840 ea22b0e14e8fa9740d504b2db9be9fb8 403 Gene3D G3DSA:1.20.1250.20 4 387 3.7E-38 T 12-10-2018 AFR_13840 ea22b0e14e8fa9740d504b2db9be9fb8 403 SUPERFAMILY SSF103473 6 396 5.36E-39 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 Gene3D G3DSA:3.40.1190.10 489 732 4.0E-36 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 Pfam PF02875 Mur ligase family, glutamate ligase domain 736 818 4.6E-8 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 Pfam PF08443 RimK-like ATP-grasp domain 220 322 7.4E-6 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 Gene3D G3DSA:3.30.470.20 376 483 3.1E-8 T 12-10-2018 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 SUPERFAMILY SSF53244 736 864 8.42E-19 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 SUPERFAMILY SSF56059 223 483 4.24E-27 T 12-10-2018 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 494 517 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 Pfam PF08245 Mur ligase middle domain 496 652 1.2E-19 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 876 8.6E-264 T 12-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 SMART SM01209 221 351 0.0029 T 12-10-2018 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 Gene3D G3DSA:3.30.1490.20 222 309 3.5E-13 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 Gene3D G3DSA:3.90.190.20 737 868 7.4E-15 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_30950 761d7855c0bc41e2ad75a7bee2d4bc5a 913 SUPERFAMILY SSF53623 455 748 1.57E-39 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_25400 89535cc89140b67153d84e31e0852149 288 SUPERFAMILY SSF161098 18 288 8.97E-56 T 12-10-2018 IPR035906 MetI-like superfamily AFR_25400 89535cc89140b67153d84e31e0852149 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 272 1.0E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_25400 89535cc89140b67153d84e31e0852149 288 Gene3D G3DSA:1.10.3720.10 16 280 1.2E-47 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41430 0a9bcd6344d64251ea4b2e925f72ccb5 240 Gene3D G3DSA:1.10.3720.10 34 230 4.1E-28 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41430 0a9bcd6344d64251ea4b2e925f72ccb5 240 SUPERFAMILY SSF161098 38 223 1.19E-29 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41430 0a9bcd6344d64251ea4b2e925f72ccb5 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 58 236 6.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30450 dd1cba5dc19b6b7ef8d0c38c0fb13b2f 258 Gene3D G3DSA:3.30.1330.30 3 95 9.4E-16 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFR_30450 dd1cba5dc19b6b7ef8d0c38c0fb13b2f 258 Pfam PF00588 SpoU rRNA Methylase family 109 251 2.1E-33 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFR_30450 dd1cba5dc19b6b7ef8d0c38c0fb13b2f 258 SMART SM00967 29 98 1.8E-10 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFR_30450 dd1cba5dc19b6b7ef8d0c38c0fb13b2f 258 Gene3D G3DSA:3.40.1280.10 96 258 7.2E-50 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFR_30450 dd1cba5dc19b6b7ef8d0c38c0fb13b2f 258 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 29 95 1.7E-5 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFR_30450 dd1cba5dc19b6b7ef8d0c38c0fb13b2f 258 SUPERFAMILY SSF75217 86 257 9.16E-38 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFR_30450 dd1cba5dc19b6b7ef8d0c38c0fb13b2f 258 SUPERFAMILY SSF55315 4 95 2.0E-16 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 SUPERFAMILY SSF52172 1 140 3.27E-17 T 12-10-2018 IPR011006 CheY-like superfamily AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 SMART SM00421 145 207 6.5E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 Pfam PF00072 Response regulator receiver domain 3 108 2.3E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 Gene3D G3DSA:3.40.50.12740 1 206 2.0E-42 T 12-10-2018 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 192 5.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 SMART SM00448 1 120 3.0E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 5.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 5.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 5.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34620 eecf7b573334d5cdf64e0f1d5b3afbe1 211 SUPERFAMILY SSF46894 138 192 2.86E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 SMART SM00829 7 338 0.0037 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 SUPERFAMILY SSF51735 146 306 2.02E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 122 1.3E-22 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 Pfam PF00107 Zinc-binding dehydrogenase 175 279 1.4E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 Gene3D G3DSA:3.90.180.10 4 330 2.4E-91 T 12-10-2018 AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 SUPERFAMILY SSF50129 1 165 3.09E-45 T 12-10-2018 IPR011032 GroES-like superfamily AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_14510 be08e1d09b22ce80e88dd061b085227b 340 Gene3D G3DSA:3.40.50.720 155 302 2.4E-91 T 12-10-2018 AFR_21525 329682bdc2266f0ac38b6ed86c527703 285 Pfam PF00296 Luciferase-like monooxygenase 19 213 6.8E-35 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_21525 329682bdc2266f0ac38b6ed86c527703 285 SUPERFAMILY SSF51679 5 254 7.07E-44 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_21525 329682bdc2266f0ac38b6ed86c527703 285 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 8 256 5.4E-106 T 12-10-2018 IPR022480 F420-dependent oxidoreductase, MSMEG2906 AFR_21525 329682bdc2266f0ac38b6ed86c527703 285 Gene3D G3DSA:3.20.20.30 8 280 1.1E-44 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_34695 38bf5d2f7b84005740da5912a56f5469 396 Gene3D G3DSA:2.10.10.20 332 396 4.4E-8 T 12-10-2018 AFR_34695 38bf5d2f7b84005740da5912a56f5469 396 SUPERFAMILY SSF51055 332 396 6.87E-7 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_34695 38bf5d2f7b84005740da5912a56f5469 396 SUPERFAMILY SSF49899 37 268 1.9E-18 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_34695 38bf5d2f7b84005740da5912a56f5469 396 Gene3D G3DSA:2.60.120.200 45 271 1.1E-15 T 12-10-2018 AFR_19995 40055db7520435c36f82d15ec023d0e1 561 Pfam PF00754 F5/8 type C domain 435 549 3.8E-20 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_19995 40055db7520435c36f82d15ec023d0e1 561 SMART SM00231 424 561 5.8E-9 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_19995 40055db7520435c36f82d15ec023d0e1 561 SUPERFAMILY SSF49785 429 548 1.35E-24 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_19995 40055db7520435c36f82d15ec023d0e1 561 Gene3D G3DSA:3.20.20.80 42 396 1.5E-16 T 12-10-2018 AFR_19995 40055db7520435c36f82d15ec023d0e1 561 Gene3D G3DSA:2.60.120.260 426 561 6.7E-33 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_03230 c15d340bb355ca0aba5915286cc122e2 300 Gene3D G3DSA:1.10.10.60 189 296 3.3E-23 T 12-10-2018 AFR_03230 c15d340bb355ca0aba5915286cc122e2 300 Pfam PF12833 Helix-turn-helix domain 211 289 1.1E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_03230 c15d340bb355ca0aba5915286cc122e2 300 Pfam PF02311 AraC-like ligand binding domain 46 108 9.7E-5 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFR_03230 c15d340bb355ca0aba5915286cc122e2 300 SUPERFAMILY SSF46689 244 292 2.87E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03230 c15d340bb355ca0aba5915286cc122e2 300 SMART SM00342 205 288 3.9E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_03230 c15d340bb355ca0aba5915286cc122e2 300 SUPERFAMILY SSF51215 45 169 1.83E-11 T 12-10-2018 IPR037923 Transcription regulator HTH-like AFR_36720 bbcd9a082c1163059e2b68fe6a870b03 267 Pfam PF10370 Domain of unknown function (DUF2437) 2 58 7.2E-16 T 12-10-2018 IPR018833 Domain of unknown function DUF2437 AFR_36720 bbcd9a082c1163059e2b68fe6a870b03 267 Gene3D G3DSA:3.90.850.10 59 266 4.1E-78 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_36720 bbcd9a082c1163059e2b68fe6a870b03 267 SUPERFAMILY SSF56529 55 264 1.44E-72 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_36720 bbcd9a082c1163059e2b68fe6a870b03 267 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 63 264 7.3E-63 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFR_36720 bbcd9a082c1163059e2b68fe6a870b03 267 Gene3D G3DSA:2.30.30.370 1 58 5.9E-14 T 12-10-2018 AFR_08905 4b383f32ec899d9f19befde3ab50c267 429 Pfam PF00704 Glycosyl hydrolases family 18 37 410 8.4E-82 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_08905 4b383f32ec899d9f19befde3ab50c267 429 SUPERFAMILY SSF51445 30 414 4.11E-88 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_08905 4b383f32ec899d9f19befde3ab50c267 429 Gene3D G3DSA:3.10.50.10 326 391 4.2E-133 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily AFR_08905 4b383f32ec899d9f19befde3ab50c267 429 SMART SM00636 34 410 2.5E-108 T 12-10-2018 IPR011583 Chitinase II GO:0008061 AFR_08905 4b383f32ec899d9f19befde3ab50c267 429 ProSitePatterns PS01095 Chitinases family 18 active site. 180 188 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_08905 4b383f32ec899d9f19befde3ab50c267 429 Gene3D G3DSA:3.20.20.80 37 414 4.2E-133 T 12-10-2018 AFR_08905 4b383f32ec899d9f19befde3ab50c267 429 SUPERFAMILY SSF54556 318 382 1.28E-6 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily AFR_21385 2888b26c1320e233b6a712250c66780e 920 SUPERFAMILY SSF46894 837 904 5.44E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21385 2888b26c1320e233b6a712250c66780e 920 SMART SM00421 846 903 1.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21385 2888b26c1320e233b6a712250c66780e 920 Pfam PF00196 Bacterial regulatory proteins, luxR family 848 903 1.3E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21385 2888b26c1320e233b6a712250c66780e 920 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 863 879 4.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21385 2888b26c1320e233b6a712250c66780e 920 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 879 891 4.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21385 2888b26c1320e233b6a712250c66780e 920 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 849 863 4.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21385 2888b26c1320e233b6a712250c66780e 920 Gene3D G3DSA:1.10.10.10 791 918 1.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21385 2888b26c1320e233b6a712250c66780e 920 SMART SM00382 16 146 0.0015 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21385 2888b26c1320e233b6a712250c66780e 920 Gene3D G3DSA:3.40.50.300 1 141 5.0E-6 T 12-10-2018 AFR_21385 2888b26c1320e233b6a712250c66780e 920 SUPERFAMILY SSF52540 12 189 4.28E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 SUPERFAMILY SSF50331 254 371 1.36E-17 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 Gene3D G3DSA:3.40.50.300 10 255 6.5E-72 T 12-10-2018 AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 51 370 6.1E-115 T 12-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 Gene3D G3DSA:2.40.50.100 298 366 5.4E-9 T 12-10-2018 AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 Pfam PF08402 TOBE domain 295 371 8.1E-16 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 SUPERFAMILY SSF52540 17 257 1.4E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 Gene3D G3DSA:2.40.50.140 256 297 5.4E-9 T 12-10-2018 AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 SMART SM00382 45 228 3.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_06655 9c05da798c378ad1728c53a4c7b6c372 377 Pfam PF00005 ABC transporter 37 178 6.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03500 fb9637be8f5c4957f4be72701a3633a9 148 Gene3D G3DSA:1.10.10.10 4 147 3.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03500 fb9637be8f5c4957f4be72701a3633a9 148 SUPERFAMILY SSF46785 17 139 1.81E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_03500 fb9637be8f5c4957f4be72701a3633a9 148 Pfam PF12802 MarR family 34 88 1.2E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_03500 fb9637be8f5c4957f4be72701a3633a9 148 SMART SM00347 28 124 4.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11810 f08e9dd19bacd89dc6706f4eb5cc917f 334 SUPERFAMILY SSF51735 119 291 1.6E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11810 f08e9dd19bacd89dc6706f4eb5cc917f 334 SUPERFAMILY SSF50129 9 145 1.46E-33 T 12-10-2018 IPR011032 GroES-like superfamily AFR_11810 f08e9dd19bacd89dc6706f4eb5cc917f 334 Gene3D G3DSA:3.40.50.720 127 277 3.8E-87 T 12-10-2018 AFR_11810 f08e9dd19bacd89dc6706f4eb5cc917f 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 3.3E-11 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_11810 f08e9dd19bacd89dc6706f4eb5cc917f 334 Gene3D G3DSA:3.90.180.10 12 328 3.8E-87 T 12-10-2018 AFR_11810 f08e9dd19bacd89dc6706f4eb5cc917f 334 SMART SM00829 10 332 2.4E-43 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_11810 f08e9dd19bacd89dc6706f4eb5cc917f 334 Pfam PF00107 Zinc-binding dehydrogenase 156 255 8.1E-28 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_33805 3bbba397289199129913c97ca3fd4341 335 Gene3D G3DSA:3.40.50.2300 53 312 7.8E-65 T 12-10-2018 AFR_33805 3bbba397289199129913c97ca3fd4341 335 Pfam PF13377 Periplasmic binding protein-like domain 176 334 1.3E-32 T 12-10-2018 AFR_33805 3bbba397289199129913c97ca3fd4341 335 SUPERFAMILY SSF53822 79 334 5.89E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_33805 3bbba397289199129913c97ca3fd4341 335 Gene3D G3DSA:3.40.50.2300 168 295 7.8E-65 T 12-10-2018 AFR_33805 3bbba397289199129913c97ca3fd4341 335 Gene3D G3DSA:1.10.260.40 1 52 3.6E-19 T 12-10-2018 AFR_33805 3bbba397289199129913c97ca3fd4341 335 SMART SM00354 1 68 3.7E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_33805 3bbba397289199129913c97ca3fd4341 335 SUPERFAMILY SSF47413 2 57 3.75E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_33805 3bbba397289199129913c97ca3fd4341 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 1.3E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 Pfam PF03704 Bacterial transcriptional activator domain 113 258 2.5E-32 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 SUPERFAMILY SSF48452 108 279 1.26E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 SMART SM00862 26 106 3.7E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 SUPERFAMILY SSF46894 13 106 1.79E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 Pfam PF12836 Helix-hairpin-helix motif 481 525 1.4E-6 T 12-10-2018 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 Gene3D G3DSA:1.25.40.10 112 274 1.4E-41 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 106 2.3E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 Gene3D G3DSA:1.10.10.10 5 109 2.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 Gene3D G3DSA:1.10.150.280 470 543 4.1E-5 T 12-10-2018 AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 SUPERFAMILY SSF47781 478 543 9.56E-8 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_06985 8f8e36c6a6e0af7ce7bc55a463e3c1d9 565 SMART SM01043 113 258 2.7E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 Gene3D G3DSA:1.10.260.40 1 71 3.9E-15 T 12-10-2018 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 Gene3D G3DSA:3.40.50.300 76 235 1.4E-26 T 12-10-2018 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SUPERFAMILY SSF47413 2 56 2.7E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SUPERFAMILY SSF52540 81 349 5.9E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 Gene3D G3DSA:1.25.40.10 465 648 1.3E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 PRINTS PR00364 Disease resistance protein signature 192 206 1.2E-7 T 12-10-2018 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 PRINTS PR00364 Disease resistance protein signature 280 294 1.2E-7 T 12-10-2018 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 PRINTS PR00364 Disease resistance protein signature 113 128 1.2E-7 T 12-10-2018 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 Pfam PF00931 NB-ARC domain 113 295 1.4E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 Pfam PF13560 Helix-turn-helix domain 2 62 4.8E-15 T 12-10-2018 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SMART SM00028 535 568 30.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SMART SM00028 695 728 5.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SMART SM00028 615 648 0.0027 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SMART SM00028 575 608 53.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SMART SM00028 655 688 0.24 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 Pfam PF13424 Tetratricopeptide repeat 616 685 1.2E-7 T 12-10-2018 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SMART SM00530 5 60 1.4E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 Gene3D G3DSA:1.25.40.10 649 744 1.0E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_11590 607af1598de48c00bfd04f7a9cb9f9f6 744 SUPERFAMILY SSF48452 535 728 7.59E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41590 d40606865d29b2557e8bd055fbe0ee25 227 Gene3D G3DSA:3.90.79.10 15 197 2.1E-41 T 12-10-2018 AFR_41590 d40606865d29b2557e8bd055fbe0ee25 227 SUPERFAMILY SSF55811 37 190 2.57E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_41590 d40606865d29b2557e8bd055fbe0ee25 227 Pfam PF00293 NUDIX domain 38 157 2.6E-12 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 188 8.7E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 1.8E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 1.8E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 1.8E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 1.8E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 SUPERFAMILY SSF56784 6 217 1.5E-28 T 12-10-2018 IPR036412 HAD-like superfamily AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 Gene3D G3DSA:3.40.50.1000 6 209 4.5E-27 T 12-10-2018 IPR023214 HAD superfamily AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 198 3.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_30180 7d2f1d4c98194bf9b903a42d409aae4c 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 95 199 2.1E-14 T 12-10-2018 AFR_17485 c605c8efe799a0664ca978fc562665f9 292 Pfam PF00106 short chain dehydrogenase 27 214 1.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17485 c605c8efe799a0664ca978fc562665f9 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_17485 c605c8efe799a0664ca978fc562665f9 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 3.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17485 c605c8efe799a0664ca978fc562665f9 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17485 c605c8efe799a0664ca978fc562665f9 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 3.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17485 c605c8efe799a0664ca978fc562665f9 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 3.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17485 c605c8efe799a0664ca978fc562665f9 292 SUPERFAMILY SSF51735 22 264 5.11E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17485 c605c8efe799a0664ca978fc562665f9 292 Gene3D G3DSA:3.40.50.720 16 292 5.3E-69 T 12-10-2018 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 PRINTS PR00207 Flagellin signature 111 134 8.5E-24 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 PRINTS PR00207 Flagellin signature 76 95 8.5E-24 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 PRINTS PR00207 Flagellin signature 37 54 8.5E-24 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 Gene3D G3DSA:1.20.1330.10 51 231 8.7E-57 T 12-10-2018 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 SUPERFAMILY SSF64518 1 281 6.02E-88 T 12-10-2018 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 Pfam PF00700 Bacterial flagellin C-terminal helical region 196 280 3.8E-27 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 Gene3D G3DSA:1.10.8.410 232 281 5.3E-27 T 12-10-2018 AFR_40400 69e423013a9c16757a0c2ff1b5e34cc0 281 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 2.1E-43 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 Gene3D G3DSA:2.130.10.30 26 297 1.0E-61 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 SMART SM00060 393 471 4.7E-4 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 Gene3D G3DSA:2.130.10.30 298 407 4.4E-17 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 61 77 4.2E-11 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 354 375 4.2E-11 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 146 162 4.2E-11 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 42 55 4.2E-11 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 162 176 4.2E-11 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 SUPERFAMILY SSF50985 184 390 5.62E-37 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 SUPERFAMILY SSF49265 390 470 1.95E-7 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 197 224 6.0E-7 T 12-10-2018 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 146 172 5.5E-9 T 12-10-2018 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 43 71 7.0E-9 T 12-10-2018 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 344 371 9.5E-6 T 12-10-2018 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 92 120 1.4E-6 T 12-10-2018 AFR_03955 bdd34bb28d7d309c3a30c32f32ace5c5 538 SUPERFAMILY SSF50985 43 239 1.44E-47 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_39810 93f30aa907b7a0399b1e07820f80a766 302 Gene3D G3DSA:3.20.20.140 27 295 2.5E-69 T 12-10-2018 AFR_39810 93f30aa907b7a0399b1e07820f80a766 302 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 32 295 7.3E-65 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 AFR_39810 93f30aa907b7a0399b1e07820f80a766 302 Pfam PF01026 TatD related DNase 33 294 2.6E-61 T 12-10-2018 IPR001130 TatD family GO:0016788 AFR_39810 93f30aa907b7a0399b1e07820f80a766 302 PIRSF PIRSF005902 2 299 2.8E-65 T 12-10-2018 IPR001130 TatD family GO:0016788 AFR_39810 93f30aa907b7a0399b1e07820f80a766 302 SUPERFAMILY SSF51556 30 295 1.87E-69 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_21715 376001a81c6464e184d34c0509d5fa93 293 Gene3D G3DSA:2.40.10.500 9 86 4.5E-5 T 12-10-2018 AFR_21715 376001a81c6464e184d34c0509d5fa93 293 Hamap MF_01282 Virginiamycin B lyase [vgb]. 5 291 41.377 T 12-10-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 AFR_21715 376001a81c6464e184d34c0509d5fa93 293 Gene3D G3DSA:2.130.10.10 87 291 2.4E-72 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_21715 376001a81c6464e184d34c0509d5fa93 293 PIRSF PIRSF026412 4 293 4.1E-98 T 12-10-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 AFR_21715 376001a81c6464e184d34c0509d5fa93 293 SUPERFAMILY SSF63829 53 280 3.27E-29 T 12-10-2018 AFR_10840 0f9d1d0b6dfda684eaba429073083d50 182 Pfam PF03167 Uracil DNA glycosylase superfamily 20 177 4.5E-27 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_10840 0f9d1d0b6dfda684eaba429073083d50 182 SUPERFAMILY SSF52141 17 179 1.44E-42 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_10840 0f9d1d0b6dfda684eaba429073083d50 182 SMART SM00986 19 177 2.3E-4 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_10840 0f9d1d0b6dfda684eaba429073083d50 182 Gene3D G3DSA:3.40.470.10 17 181 7.4E-62 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_10840 0f9d1d0b6dfda684eaba429073083d50 182 SMART SM00987 19 177 2.3E-4 T 12-10-2018 AFR_41950 c0d302625c5ccc636d032d624bf363e2 156 Pfam PF03259 Roadblock/LC7 domain 28 118 7.4E-15 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_41950 c0d302625c5ccc636d032d624bf363e2 156 SMART SM00960 28 118 2.5E-21 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_41950 c0d302625c5ccc636d032d624bf363e2 156 SUPERFAMILY SSF103196 23 143 2.96E-25 T 12-10-2018 AFR_41950 c0d302625c5ccc636d032d624bf363e2 156 Gene3D G3DSA:3.30.450.30 24 146 4.1E-33 T 12-10-2018 AFR_14950 34026561b204783a20d6dc507311c0ca 443 Gene3D G3DSA:3.40.190.10 30 443 2.7E-90 T 12-10-2018 AFR_14950 34026561b204783a20d6dc507311c0ca 443 Pfam PF13416 Bacterial extracellular solute-binding protein 53 371 4.0E-32 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_14950 34026561b204783a20d6dc507311c0ca 443 SUPERFAMILY SSF53850 21 442 4.81E-69 T 12-10-2018 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 SUPERFAMILY SSF50692 586 731 7.23E-36 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 Pfam PF01568 Molydopterin dinucleotide binding domain 593 706 2.2E-20 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 Pfam PF00384 Molybdopterin oxidoreductase 48 491 6.6E-51 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 SUPERFAMILY SSF53706 18 593 6.28E-130 T 12-10-2018 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 436 453 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 Gene3D G3DSA:3.40.228.10 132 566 8.8E-154 T 12-10-2018 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 Gene3D G3DSA:3.40.50.740 30 500 8.8E-154 T 12-10-2018 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 Gene3D G3DSA:2.40.40.20 574 728 1.1E-39 T 12-10-2018 AFR_32745 a3d424fb97ad2a550a9a145cfef055f7 735 Gene3D G3DSA:3.90.55.10 6 536 8.8E-154 T 12-10-2018 AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 Pfam PF00206 Lyase 284 353 1.4E-9 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 Pfam PF00206 Lyase 35 205 3.8E-19 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 5.6E-7 T 12-10-2018 IPR000362 Fumarate lyase family AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 5.6E-7 T 12-10-2018 IPR000362 Fumarate lyase family AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 Gene3D G3DSA:1.20.200.10 236 414 5.4E-46 T 12-10-2018 AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 Gene3D G3DSA:1.20.200.10 108 235 2.0E-31 T 12-10-2018 AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 SMART SM00998 417 486 1.1E-4 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 SUPERFAMILY SSF48557 22 488 2.64E-75 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 Gene3D G3DSA:1.10.275.10 8 107 4.6E-21 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_19270 defd3f56c20e742edfd7f2fe6a2e98b7 491 Gene3D G3DSA:1.10.40.30 416 491 1.9E-9 T 12-10-2018 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 SUPERFAMILY SSF55781 326 391 4.42E-5 T 12-10-2018 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 SUPERFAMILY SSF47384 387 468 2.16E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 Gene3D G3DSA:1.20.1440.210 36 156 1.5E-12 T 12-10-2018 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 Pfam PF00512 His Kinase A (phospho-acceptor) domain 403 468 3.4E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 SUPERFAMILY SSF55874 468 625 2.75E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_23995 930d9b65fbea5be505afc4221b34878f 630 Gene3D G3DSA:1.10.287.130 366 468 2.4E-18 T 12-10-2018 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 SMART SM00388 402 470 2.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 Pfam PF05227 CHASE3 domain 32 158 5.8E-17 T 12-10-2018 IPR007891 CHASE3 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 585 603 1.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 609 622 1.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 564 1.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 578 1.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_23995 930d9b65fbea5be505afc4221b34878f 630 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 513 623 2.8E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_23995 930d9b65fbea5be505afc4221b34878f 630 Gene3D G3DSA:3.30.565.10 477 626 2.3E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_23995 930d9b65fbea5be505afc4221b34878f 630 SMART SM00387 513 625 1.1E-35 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_23995 930d9b65fbea5be505afc4221b34878f 630 SMART SM00304 190 242 3.3E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 Pfam PF03167 Uracil DNA glycosylase superfamily 54 208 7.4E-21 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 9 214 5.4E-74 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 SUPERFAMILY SSF52141 6 221 1.02E-79 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 12-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 8 222 37.586 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 SMART SM00987 52 211 2.5E-35 T 12-10-2018 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 Gene3D G3DSA:3.40.470.10 2 225 5.7E-88 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_04850 5f2bc63b2df432fd7cc0000cfa051195 225 SMART SM00986 52 211 2.5E-35 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 Pfam PF00905 Penicillin binding protein transpeptidase domain 332 581 5.1E-23 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 Gene3D G3DSA:1.10.3810.10 61 255 5.2E-65 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 Gene3D G3DSA:3.40.710.10 687 913 1.6E-30 T 12-10-2018 AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 Pfam PF00912 Transglycosylase 70 241 1.5E-58 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 SUPERFAMILY SSF56601 223 630 6.36E-71 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 Gene3D G3DSA:3.40.710.10 271 641 2.5E-85 T 12-10-2018 AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 Pfam PF13354 Beta-lactamase enzyme family 752 888 1.8E-5 T 12-10-2018 AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 SUPERFAMILY SSF56601 697 899 3.76E-25 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_15355 a5df2ad07e037a17258009de4b1c0af8 915 SUPERFAMILY SSF53955 55 255 3.94E-68 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_19495 a875324138662e342a3eaefb21de57a5 220 Gene3D G3DSA:3.40.50.7700 92 220 5.1E-30 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFR_19495 a875324138662e342a3eaefb21de57a5 220 Pfam PF00731 AIR carboxylase 92 218 8.3E-14 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFR_19495 a875324138662e342a3eaefb21de57a5 220 SMART SM01001 90 219 9.0E-18 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFR_19495 a875324138662e342a3eaefb21de57a5 220 SUPERFAMILY SSF52255 91 218 1.83E-25 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 116 133 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 SUPERFAMILY SSF51735 1 119 2.49E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 SUPERFAMILY SSF55347 95 205 7.85E-38 T 12-10-2018 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 94 3.7E-18 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 31 233 2.4E-56 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 Gene3D G3DSA:3.40.50.720 1 223 1.9E-78 T 12-10-2018 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 PIRSF PIRSF000161 1 234 7.9E-57 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 97 224 9.0E-32 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 234 24.928 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35895 63a0b12e3c266508d1ae42d15f24995a 234 Gene3D G3DSA:3.30.360.10 95 203 1.9E-78 T 12-10-2018 AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 Gene3D G3DSA:3.40.50.300 1 192 1.8E-62 T 12-10-2018 AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 Pfam PF04229 GrpB protein 210 373 6.9E-43 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 SUPERFAMILY SSF52540 1 191 8.82E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 Pfam PF01121 Dephospho-CoA kinase 1 176 9.8E-54 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 1 184 4.6E-41 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 189 22.671 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 SUPERFAMILY SSF81301 212 382 1.37E-38 T 12-10-2018 AFR_10460 0b1c91260f9ebd6577eb9ad22e96d517 391 Gene3D G3DSA:3.30.460.10 206 382 9.7E-38 T 12-10-2018 AFR_14395 5271796d9d0659e58546c70115591779 201 Gene3D G3DSA:1.10.357.10 72 198 1.3E-31 T 12-10-2018 AFR_14395 5271796d9d0659e58546c70115591779 201 SUPERFAMILY SSF46689 5 79 5.99E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14395 5271796d9d0659e58546c70115591779 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_14395 5271796d9d0659e58546c70115591779 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14395 5271796d9d0659e58546c70115591779 201 Gene3D G3DSA:1.10.10.60 3 71 7.5E-28 T 12-10-2018 AFR_14395 5271796d9d0659e58546c70115591779 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14395 5271796d9d0659e58546c70115591779 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14395 5271796d9d0659e58546c70115591779 201 SUPERFAMILY SSF48498 82 196 3.14E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 SMART SM00220 14 267 6.6E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 PIRSF PIRSF000654 27 275 1.6E-22 T 12-10-2018 AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 Gene3D G3DSA:1.10.510.10 93 274 8.6E-43 T 12-10-2018 AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 Pfam PF00069 Protein kinase domain 14 264 9.9E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 Gene3D G3DSA:3.30.200.20 7 92 8.9E-20 T 12-10-2018 AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 42 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_05580 d6b7a438c0158f03c6b8fbac5b59abf5 494 SUPERFAMILY SSF56112 10 292 1.32E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_06485 61a0fca96bb959ba0eaa820c7aea1da4 243 Pfam PF13462 Thioredoxin 81 239 4.1E-23 T 12-10-2018 IPR012336 Thioredoxin-like fold AFR_06485 61a0fca96bb959ba0eaa820c7aea1da4 243 SUPERFAMILY SSF52833 70 232 1.94E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_06485 61a0fca96bb959ba0eaa820c7aea1da4 243 Gene3D G3DSA:3.40.30.10 49 243 9.0E-53 T 12-10-2018 AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 Pfam PF03924 CHASE domain 84 251 5.7E-13 T 12-10-2018 IPR006189 CHASE domain AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 SMART SM00267 360 528 4.8E-57 T 12-10-2018 IPR000160 GGDEF domain AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 Pfam PF00563 EAL domain 544 773 2.6E-73 T 12-10-2018 IPR001633 EAL domain AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 Pfam PF00990 Diguanylate cyclase, GGDEF domain 371 521 6.8E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 SUPERFAMILY SSF141868 544 785 7.85E-86 T 12-10-2018 IPR035919 EAL domain superfamily AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 Gene3D G3DSA:3.20.20.450 541 787 8.1E-96 T 12-10-2018 IPR035919 EAL domain superfamily AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 SMART SM00052 538 778 1.2E-112 T 12-10-2018 IPR001633 EAL domain AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 SUPERFAMILY SSF55073 376 530 1.88E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 Gene3D G3DSA:3.30.70.270 357 529 1.7E-52 T 12-10-2018 AFR_35365 8d8584ea0b4a9455766c0b502da1df9e 794 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 367 527 1.0E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 468 7.2E-165 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 SUPERFAMILY SSF50800 73 167 2.09E-26 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 467 7.5E-25 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.3E-65 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.3E-65 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 PRINTS PR01050 Pyruvate kinase family signature 62 78 1.3E-65 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.3E-65 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.3E-65 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.3E-65 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.3E-65 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 SUPERFAMILY SSF52935 344 469 2.09E-35 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 Gene3D G3DSA:3.40.1380.20 336 465 3.7E-170 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 SUPERFAMILY SSF51621 3 337 1.08E-96 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 Gene3D G3DSA:3.20.20.60 5 335 3.7E-170 T 12-10-2018 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 Pfam PF00224 Pyruvate kinase, barrel domain 5 337 1.5E-121 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_10365 f40a18c3f79cf730f7b6f34f70f455f9 482 Gene3D G3DSA:2.40.33.10 73 169 3.7E-170 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFR_15545 a242f85ebf9f826afc2c245822136623 137 Pfam PF12802 MarR family 30 85 5.1E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15545 a242f85ebf9f826afc2c245822136623 137 SMART SM00347 25 123 9.3E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15545 a242f85ebf9f826afc2c245822136623 137 SUPERFAMILY SSF46785 6 135 2.99E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15545 a242f85ebf9f826afc2c245822136623 137 Gene3D G3DSA:1.10.10.10 5 135 3.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36815 adae6cdc5478ae51a87b0ab705595caf 332 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 112 320 5.8E-19 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_36815 adae6cdc5478ae51a87b0ab705595caf 332 SUPERFAMILY SSF56219 109 324 2.09E-24 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_36815 adae6cdc5478ae51a87b0ab705595caf 332 Gene3D G3DSA:3.60.10.10 108 331 1.1E-27 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_11175 39a89aa44407566444719a7790c6ff44 450 SUPERFAMILY SSF53623 110 299 4.71E-34 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_11175 39a89aa44407566444719a7790c6ff44 450 SUPERFAMILY SSF53244 308 448 2.88E-27 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_11175 39a89aa44407566444719a7790c6ff44 450 Gene3D G3DSA:3.40.50.720 4 99 2.4E-12 T 12-10-2018 AFR_11175 39a89aa44407566444719a7790c6ff44 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 9 449 26.067 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFR_11175 39a89aa44407566444719a7790c6ff44 450 Pfam PF08245 Mur ligase middle domain 116 284 7.7E-19 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_11175 39a89aa44407566444719a7790c6ff44 450 Gene3D G3DSA:3.90.190.20 313 448 3.7E-29 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_11175 39a89aa44407566444719a7790c6ff44 450 Gene3D G3DSA:3.40.1190.10 101 308 4.5E-39 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_11175 39a89aa44407566444719a7790c6ff44 450 SUPERFAMILY SSF51984 5 99 9.02E-9 T 12-10-2018 AFR_11175 39a89aa44407566444719a7790c6ff44 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 447 1.7E-86 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFR_12825 e2b56fb8dee454ddbc0462cbf69ba866 204 SUPERFAMILY SSF48498 81 197 7.56E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12825 e2b56fb8dee454ddbc0462cbf69ba866 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 192 1.4E-19 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_12825 e2b56fb8dee454ddbc0462cbf69ba866 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 8.4E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12825 e2b56fb8dee454ddbc0462cbf69ba866 204 SUPERFAMILY SSF46689 10 74 3.49E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12825 e2b56fb8dee454ddbc0462cbf69ba866 204 Gene3D G3DSA:1.10.357.10 61 201 3.6E-18 T 12-10-2018 AFR_12825 e2b56fb8dee454ddbc0462cbf69ba866 204 Gene3D G3DSA:1.10.10.60 6 60 6.0E-13 T 12-10-2018 AFR_35750 eca176278d7e4bcb7d349580377c6b9a 174 Gene3D G3DSA:3.40.630.30 1 162 2.5E-37 T 12-10-2018 AFR_35750 eca176278d7e4bcb7d349580377c6b9a 174 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 1.7E-22 T 12-10-2018 IPR000182 GNAT domain AFR_35750 eca176278d7e4bcb7d349580377c6b9a 174 SUPERFAMILY SSF55729 2 149 3.29E-31 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.6E-37 T 12-10-2018 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 5.6E-37 T 12-10-2018 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 5.6E-37 T 12-10-2018 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 5.6E-37 T 12-10-2018 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 5.6E-37 T 12-10-2018 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 Gene3D G3DSA:3.50.50.60 8 331 1.9E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 Gene3D G3DSA:3.40.30.120 378 467 5.0E-14 T 12-10-2018 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 Pfam PF01494 FAD binding domain 7 332 4.8E-68 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 Gene3D G3DSA:3.30.70.2450 179 258 1.9E-95 T 12-10-2018 AFR_32135 47f1122c07b12787a135f4f51129b4d8 469 SUPERFAMILY SSF51905 7 345 1.79E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_42025 d662ff41ae35e63fda5de37985715dcb 155 Pfam PF01047 MarR family 43 93 7.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_42025 d662ff41ae35e63fda5de37985715dcb 155 Gene3D G3DSA:1.10.10.10 4 144 5.9E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42025 d662ff41ae35e63fda5de37985715dcb 155 SMART SM00347 29 129 3.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_42025 d662ff41ae35e63fda5de37985715dcb 155 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_42025 d662ff41ae35e63fda5de37985715dcb 155 SUPERFAMILY SSF46785 19 144 3.86E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Gene3D G3DSA:1.10.8.60 720 820 4.1E-27 T 12-10-2018 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 1.7E-18 T 12-10-2018 IPR004176 Clp, N-terminal AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.6E-17 T 12-10-2018 IPR004176 Clp, N-terminal AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 SMART SM01086 720 809 2.3E-35 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 SMART SM00382 205 349 2.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 SMART SM00382 542 682 3.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Gene3D G3DSA:3.40.50.300 158 348 1.5E-70 T 12-10-2018 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Gene3D G3DSA:3.40.50.300 349 469 3.7E-38 T 12-10-2018 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 SUPERFAMILY SSF52540 168 469 1.85E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 713 2.1E-51 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 SUPERFAMILY SSF81923 3 144 8.14E-33 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Gene3D G3DSA:3.40.50.300 472 718 1.0E-94 T 12-10-2018 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 720 800 7.6E-25 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 9.4E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 9.4E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 9.4E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 9.4E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Pfam PF02151 UvrB/uvrC motif 422 454 9.1E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 SUPERFAMILY SSF52540 491 802 3.86E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Gene3D G3DSA:1.10.1780.10 1 148 2.6E-64 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_41355 db0968bd1bd162b68812ef4258b5a243 840 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 326 3.6E-12 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_37465 e2081f064f1a710e9e0b985f6b0353e3 447 Gene3D G3DSA:1.20.1250.20 9 392 2.3E-29 T 12-10-2018 AFR_37465 e2081f064f1a710e9e0b985f6b0353e3 447 Pfam PF07690 Major Facilitator Superfamily 26 360 5.8E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_37465 e2081f064f1a710e9e0b985f6b0353e3 447 SUPERFAMILY SSF103473 10 394 3.01E-35 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_33800 3fca0e4635fe55f41d27ff1dfd54f106 423 Gene3D G3DSA:2.60.120.260 34 157 1.7E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33800 3fca0e4635fe55f41d27ff1dfd54f106 423 Pfam PF00754 F5/8 type C domain 40 152 2.7E-25 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33800 3fca0e4635fe55f41d27ff1dfd54f106 423 SUPERFAMILY SSF49785 39 157 1.38E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33800 3fca0e4635fe55f41d27ff1dfd54f106 423 Pfam PF09362 Domain of unknown function (DUF1996) 191 398 7.4E-47 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_33800 3fca0e4635fe55f41d27ff1dfd54f106 423 SMART SM00231 26 158 0.0064 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_21500 0098d4af9d24d6795c71d5731583d52e 263 Gene3D G3DSA:3.60.10.10 1 259 2.6E-43 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_21500 0098d4af9d24d6795c71d5731583d52e 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 7.9E-17 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_21500 0098d4af9d24d6795c71d5731583d52e 263 SUPERFAMILY SSF56219 1 260 3.53E-30 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_11840 7796d7521db41b715e73f2444866d4ee 539 Pfam PF16124 RecQ zinc-binding 427 474 1.5E-9 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain AFR_11840 7796d7521db41b715e73f2444866d4ee 539 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 11 346 1.9E-98 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 AFR_11840 7796d7521db41b715e73f2444866d4ee 539 Pfam PF00271 Helicase conserved C-terminal domain 233 328 2.9E-17 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_11840 7796d7521db41b715e73f2444866d4ee 539 SMART SM00487 12 210 1.3E-21 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_11840 7796d7521db41b715e73f2444866d4ee 539 SUPERFAMILY SSF52540 55 345 1.01E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11840 7796d7521db41b715e73f2444866d4ee 539 SMART SM00490 248 329 7.3E-28 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_11840 7796d7521db41b715e73f2444866d4ee 539 Pfam PF00270 DEAD/DEAH box helicase 18 179 5.6E-13 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_11840 7796d7521db41b715e73f2444866d4ee 539 Gene3D G3DSA:3.40.50.300 2 200 5.6E-64 T 12-10-2018 AFR_30420 d860de0322493d9cb58e178c67bf0bbc 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 6 76 1.7E-12 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_30420 d860de0322493d9cb58e178c67bf0bbc 98 SUPERFAMILY SSF54909 1 96 3.07E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_30420 d860de0322493d9cb58e178c67bf0bbc 98 Gene3D G3DSA:3.30.70.100 1 97 1.1E-16 T 12-10-2018 AFR_10390 ab0c7af22618c3e5ab7c92ddaa8adf1f 331 Gene3D G3DSA:3.40.50.2300 2 299 7.0E-69 T 12-10-2018 AFR_10390 ab0c7af22618c3e5ab7c92ddaa8adf1f 331 SUPERFAMILY SSF53822 3 315 4.71E-56 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_10390 ab0c7af22618c3e5ab7c92ddaa8adf1f 331 Gene3D G3DSA:3.40.50.2300 101 229 7.0E-69 T 12-10-2018 AFR_10390 ab0c7af22618c3e5ab7c92ddaa8adf1f 331 Pfam PF13458 Periplasmic binding protein 4 301 4.9E-36 T 12-10-2018 IPR028081 Leucine-binding protein domain AFR_04565 0f344e2d9ca805c96e7af8ec17c70fa7 189 Pfam PF00673 ribosomal L5P family C-terminus 93 186 1.5E-36 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04565 0f344e2d9ca805c96e7af8ec17c70fa7 189 Pfam PF00281 Ribosomal protein L5 33 89 7.4E-27 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04565 0f344e2d9ca805c96e7af8ec17c70fa7 189 SUPERFAMILY SSF55282 12 187 6.83E-71 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04565 0f344e2d9ca805c96e7af8ec17c70fa7 189 Gene3D G3DSA:3.30.1440.10 9 188 3.9E-73 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04565 0f344e2d9ca805c96e7af8ec17c70fa7 189 PIRSF PIRSF002161 6 189 2.8E-61 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04565 0f344e2d9ca805c96e7af8ec17c70fa7 189 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 10 188 41.917 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_24380 030801c4b39649df540e948fac106518 303 Pfam PF00892 EamA-like transporter family 6 134 3.9E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_24380 030801c4b39649df540e948fac106518 303 Pfam PF00892 EamA-like transporter family 146 279 2.8E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_24380 030801c4b39649df540e948fac106518 303 SUPERFAMILY SSF103481 39 137 1.83E-11 T 12-10-2018 AFR_24380 030801c4b39649df540e948fac106518 303 SUPERFAMILY SSF103481 186 279 1.12E-12 T 12-10-2018 AFR_31550 3396ce6912f389678bc943b7ced22f20 821 SUPERFAMILY SSF52540 22 346 2.09E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31550 3396ce6912f389678bc943b7ced22f20 821 Gene3D G3DSA:1.20.120.1080 383 471 2.6E-9 T 12-10-2018 AFR_31550 3396ce6912f389678bc943b7ced22f20 821 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 11 820 9.4E-237 T 12-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 AFR_31550 3396ce6912f389678bc943b7ced22f20 821 Pfam PF08482 ATP-dependent helicase C-terminal 681 808 2.7E-50 T 12-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal AFR_31550 3396ce6912f389678bc943b7ced22f20 821 SMART SM00487 9 189 7.7E-17 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_31550 3396ce6912f389678bc943b7ced22f20 821 SMART SM00490 239 336 2.6E-12 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_31550 3396ce6912f389678bc943b7ced22f20 821 Pfam PF00271 Helicase conserved C-terminal domain 221 334 6.7E-9 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_31550 3396ce6912f389678bc943b7ced22f20 821 Gene3D G3DSA:3.40.50.300 183 355 1.7E-43 T 12-10-2018 AFR_31550 3396ce6912f389678bc943b7ced22f20 821 SMART SM00847 396 483 1.0E-6 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 AFR_31550 3396ce6912f389678bc943b7ced22f20 821 Pfam PF04408 Helicase associated domain (HA2) 397 453 3.8E-9 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 AFR_31550 3396ce6912f389678bc943b7ced22f20 821 Gene3D G3DSA:3.40.50.300 5 181 1.5E-50 T 12-10-2018 AFR_31550 3396ce6912f389678bc943b7ced22f20 821 PIRSF PIRSF005496 6 821 8.0E-268 T 12-10-2018 AFR_17395 d102128d686d019579bbe04f1c1d4625 195 SUPERFAMILY SSF88946 7 104 3.45E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_17395 d102128d686d019579bbe04f1c1d4625 195 Pfam PF04542 Sigma-70 region 2 29 95 2.4E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_17395 d102128d686d019579bbe04f1c1d4625 195 Gene3D G3DSA:1.10.10.10 110 191 3.0E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17395 d102128d686d019579bbe04f1c1d4625 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 186 4.4E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_17395 d102128d686d019579bbe04f1c1d4625 195 Gene3D G3DSA:1.10.1740.10 4 109 1.1E-19 T 12-10-2018 AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 41 1.0E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 SMART SM00354 1 65 1.5E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 Gene3D G3DSA:3.40.50.2300 49 297 4.0E-56 T 12-10-2018 AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 SUPERFAMILY SSF53822 53 313 6.44E-49 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 Pfam PF13377 Periplasmic binding protein-like domain 161 319 1.0E-32 T 12-10-2018 AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 Gene3D G3DSA:3.40.50.2300 153 280 4.0E-56 T 12-10-2018 AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 Gene3D G3DSA:1.10.260.40 1 48 1.0E-16 T 12-10-2018 AFR_13180 5a60f8c9c2e9b7b889093536c4f8b969 319 SUPERFAMILY SSF47413 1 53 4.22E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 SUPERFAMILY SSF54373 169 264 2.79E-33 T 12-10-2018 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 Gene3D G3DSA:3.50.50.60 2 340 1.2E-161 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.3E-28 T 12-10-2018 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 2.3E-28 T 12-10-2018 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 2.3E-28 T 12-10-2018 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 2.3E-28 T 12-10-2018 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 317 2.3E-28 T 12-10-2018 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 Gene3D G3DSA:3.30.9.10 73 376 1.2E-161 T 12-10-2018 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 Pfam PF01494 FAD binding domain 2 332 1.1E-72 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_19295 e64daccf601d67e4a57c70ecefc6715f 379 SUPERFAMILY SSF51905 1 377 1.17E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 SMART SM00448 4 118 5.3E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 SUPERFAMILY SSF52172 3 150 1.85E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 SMART SM00331 300 510 7.5E-30 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 Gene3D G3DSA:3.40.50.12740 3 211 4.6E-40 T 12-10-2018 AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 Gene3D G3DSA:3.60.40.10 295 511 1.6E-61 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 SUPERFAMILY SSF81606 313 509 1.6E-10 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 329 510 2.1E-44 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_01235 cdda517df35cbd7ffb10741c92bd1fa7 516 Pfam PF00072 Response regulator receiver domain 6 116 3.2E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 Gene3D G3DSA:3.40.50.300 349 592 4.0E-79 T 12-10-2018 AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 Pfam PF00664 ABC transporter transmembrane region 34 305 1.7E-33 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 Pfam PF00005 ABC transporter 368 517 1.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 Gene3D G3DSA:1.20.1560.10 4 338 4.7E-63 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 SUPERFAMILY SSF90123 18 338 1.2E-64 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 SMART SM00382 377 563 4.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10250 cd703e6aa9d4fd3ed446f6ef9931f93c 593 SUPERFAMILY SSF52540 343 588 4.32E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11520 fe240db658309e31a2d758e6fcbae1ed 288 Pfam PF00248 Aldo/keto reductase family 22 286 1.4E-44 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_11520 fe240db658309e31a2d758e6fcbae1ed 288 PRINTS PR00069 Aldo-keto reductase signature 150 167 1.1E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_11520 fe240db658309e31a2d758e6fcbae1ed 288 PRINTS PR00069 Aldo-keto reductase signature 220 244 1.1E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_11520 fe240db658309e31a2d758e6fcbae1ed 288 PRINTS PR00069 Aldo-keto reductase signature 50 74 1.1E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_11520 fe240db658309e31a2d758e6fcbae1ed 288 Gene3D G3DSA:3.20.20.100 11 287 3.0E-64 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_11520 fe240db658309e31a2d758e6fcbae1ed 288 SUPERFAMILY SSF51430 15 286 8.51E-63 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_20420 ab717562ed2c0decda9ec4d5c809eb62 396 Gene3D G3DSA:2.60.120.260 5 162 2.9E-45 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_20420 ab717562ed2c0decda9ec4d5c809eb62 396 SUPERFAMILY SSF52266 166 375 4.37E-25 T 12-10-2018 AFR_20420 ab717562ed2c0decda9ec4d5c809eb62 396 Gene3D G3DSA:3.40.50.1110 168 382 1.5E-66 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_20420 ab717562ed2c0decda9ec4d5c809eb62 396 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 173 272 9.2E-12 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_19175 ef7dd55cb62e18040b6a5b7182145b5f 355 Gene3D G3DSA:1.20.1280.290 1 91 2.3E-12 T 12-10-2018 AFR_19175 ef7dd55cb62e18040b6a5b7182145b5f 355 Pfam PF04193 PQ loop repeat 6 43 2.2E-4 T 12-10-2018 IPR006603 PQ-loop repeat AFR_19175 ef7dd55cb62e18040b6a5b7182145b5f 355 Gene3D G3DSA:1.20.1280.290 121 209 4.3E-8 T 12-10-2018 AFR_16995 da084da48712062dc181225211179b2e 1000 SMART SM00267 551 724 9.6E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_16995 da084da48712062dc181225211179b2e 1000 Pfam PF00563 EAL domain 740 976 2.6E-70 T 12-10-2018 IPR001633 EAL domain AFR_16995 da084da48712062dc181225211179b2e 1000 SUPERFAMILY SSF141868 741 988 3.92E-84 T 12-10-2018 IPR035919 EAL domain superfamily AFR_16995 da084da48712062dc181225211179b2e 1000 SUPERFAMILY SSF55785 461 559 3.02E-7 T 12-10-2018 IPR035965 PAS domain superfamily AFR_16995 da084da48712062dc181225211179b2e 1000 SUPERFAMILY SSF55073 567 718 5.26E-30 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_16995 da084da48712062dc181225211179b2e 1000 SMART SM00052 734 981 1.4E-114 T 12-10-2018 IPR001633 EAL domain AFR_16995 da084da48712062dc181225211179b2e 1000 Gene3D G3DSA:3.20.20.450 735 997 5.8E-96 T 12-10-2018 IPR035919 EAL domain superfamily AFR_16995 da084da48712062dc181225211179b2e 1000 Gene3D G3DSA:3.30.450.20 421 549 2.9E-11 T 12-10-2018 AFR_16995 da084da48712062dc181225211179b2e 1000 Gene3D G3DSA:3.30.70.270 550 724 2.3E-37 T 12-10-2018 AFR_16995 da084da48712062dc181225211179b2e 1000 Pfam PF00990 Diguanylate cyclase, GGDEF domain 562 716 5.9E-29 T 12-10-2018 IPR000160 GGDEF domain AFR_16995 da084da48712062dc181225211179b2e 1000 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 560 716 6.1E-25 T 12-10-2018 IPR000160 GGDEF domain AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 Pfam PF00571 CBS domain 336 389 3.4E-6 T 12-10-2018 IPR000644 CBS domain AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 Pfam PF00571 CBS domain 404 451 0.0055 T 12-10-2018 IPR000644 CBS domain AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 Gene3D G3DSA:3.10.580.10 331 452 1.4E-16 T 12-10-2018 AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 Gene3D G3DSA:3.40.50.1100 41 154 1.6E-121 T 12-10-2018 AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 5 451 2.4E-197 T 12-10-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 SUPERFAMILY SSF53686 2 315 3.4E-97 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 SUPERFAMILY SSF54631 334 451 3.67E-15 T 12-10-2018 AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 SMART SM00116 407 452 4.1 T 12-10-2018 IPR000644 CBS domain AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 SMART SM00116 337 390 2.2E-4 T 12-10-2018 IPR000644 CBS domain AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 Gene3D G3DSA:3.40.50.1100 9 302 1.6E-121 T 12-10-2018 AFR_05430 5ccea7a01992ee4fe5721aa33102c7eb 452 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 294 1.0E-67 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_27285 d616010585c23666f8b906c9796d6f64 560 Gene3D G3DSA:2.130.10.30 67 422 5.5E-73 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_27285 d616010585c23666f8b906c9796d6f64 560 SUPERFAMILY SSF50985 270 415 8.89E-20 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_27285 d616010585c23666f8b906c9796d6f64 560 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 150 191 2.6E-8 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 88 138 1.1E-5 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 199 242 2.4E-8 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 SMART SM00060 428 509 6.6E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_27285 d616010585c23666f8b906c9796d6f64 560 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 284 310 5.2E-6 T 12-10-2018 AFR_27285 d616010585c23666f8b906c9796d6f64 560 SUPERFAMILY SSF49265 422 510 1.1E-9 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_27285 d616010585c23666f8b906c9796d6f64 560 Pfam PF00041 Fibronectin type III domain 432 508 8.9E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_27285 d616010585c23666f8b906c9796d6f64 560 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 197 211 5.2E-14 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 287 305 5.2E-14 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 69 82 5.2E-14 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 88 104 5.2E-14 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 181 197 5.2E-14 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 340 361 5.2E-14 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_27285 d616010585c23666f8b906c9796d6f64 560 Gene3D G3DSA:2.60.40.10 435 515 3.8E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27285 d616010585c23666f8b906c9796d6f64 560 SUPERFAMILY SSF50985 72 275 1.05E-45 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_03120 aea9d42209e9117425765473f4280a2c 394 SUPERFAMILY SSF50129 1 181 1.43E-59 T 12-10-2018 IPR011032 GroES-like superfamily AFR_03120 aea9d42209e9117425765473f4280a2c 394 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_03120 aea9d42209e9117425765473f4280a2c 394 Pfam PF00107 Zinc-binding dehydrogenase 189 258 8.8E-13 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_03120 aea9d42209e9117425765473f4280a2c 394 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 2.2E-12 T 12-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated AFR_03120 aea9d42209e9117425765473f4280a2c 394 Gene3D G3DSA:3.90.180.10 4 381 2.2E-126 T 12-10-2018 AFR_03120 aea9d42209e9117425765473f4280a2c 394 SUPERFAMILY SSF51735 156 352 4.68E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03120 aea9d42209e9117425765473f4280a2c 394 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 9.5E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_03120 aea9d42209e9117425765473f4280a2c 394 Gene3D G3DSA:3.40.50.720 169 352 2.2E-126 T 12-10-2018 AFR_01165 8bd62ea63956d946d83925aea7389658 258 Gene3D G3DSA:1.10.101.10 54 131 1.4E-25 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_01165 8bd62ea63956d946d83925aea7389658 258 Pfam PF01471 Putative peptidoglycan binding domain 70 125 7.2E-16 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_01165 8bd62ea63956d946d83925aea7389658 258 Pfam PF03734 L,D-transpeptidase catalytic domain 139 246 2.4E-12 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_01165 8bd62ea63956d946d83925aea7389658 258 SUPERFAMILY SSF141523 137 257 5.49E-16 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_01165 8bd62ea63956d946d83925aea7389658 258 Gene3D G3DSA:2.40.440.10 132 258 1.3E-31 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_01165 8bd62ea63956d946d83925aea7389658 258 SUPERFAMILY SSF47090 57 126 9.42E-19 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_26795 02497100ac16893dc988da5692da82fd 615 SUPERFAMILY SSF46579 413 500 5.49E-6 T 12-10-2018 AFR_26795 02497100ac16893dc988da5692da82fd 615 SMART SM00091 497 566 2.8E-6 T 12-10-2018 IPR000014 PAS domain AFR_26795 02497100ac16893dc988da5692da82fd 615 SMART SM00091 295 360 14.0 T 12-10-2018 IPR000014 PAS domain AFR_26795 02497100ac16893dc988da5692da82fd 615 PRINTS PR00996 Glutamate methyltransferase family signature 104 124 1.1E-29 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_26795 02497100ac16893dc988da5692da82fd 615 PRINTS PR00996 Glutamate methyltransferase family signature 225 248 1.1E-29 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_26795 02497100ac16893dc988da5692da82fd 615 PRINTS PR00996 Glutamate methyltransferase family signature 64 76 1.1E-29 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_26795 02497100ac16893dc988da5692da82fd 615 PRINTS PR00996 Glutamate methyltransferase family signature 206 220 1.1E-29 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_26795 02497100ac16893dc988da5692da82fd 615 PRINTS PR00996 Glutamate methyltransferase family signature 27 40 1.1E-29 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_26795 02497100ac16893dc988da5692da82fd 615 PRINTS PR00996 Glutamate methyltransferase family signature 140 156 1.1E-29 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_26795 02497100ac16893dc988da5692da82fd 615 SUPERFAMILY SSF53335 71 265 3.52E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_26795 02497100ac16893dc988da5692da82fd 615 Pfam PF08448 PAS fold 302 410 1.5E-8 T 12-10-2018 IPR013656 PAS fold-4 AFR_26795 02497100ac16893dc988da5692da82fd 615 Pfam PF01739 CheR methyltransferase, SAM binding domain 71 261 6.7E-52 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AFR_26795 02497100ac16893dc988da5692da82fd 615 Gene3D G3DSA:3.30.450.20 483 609 5.4E-13 T 12-10-2018 AFR_26795 02497100ac16893dc988da5692da82fd 615 Gene3D G3DSA:3.30.450.20 294 422 2.1E-13 T 12-10-2018 AFR_26795 02497100ac16893dc988da5692da82fd 615 SUPERFAMILY SSF47757 4 73 1.96E-13 T 12-10-2018 AFR_26795 02497100ac16893dc988da5692da82fd 615 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 497 599 2.7E-9 T 12-10-2018 IPR000014 PAS domain AFR_26795 02497100ac16893dc988da5692da82fd 615 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 296 413 1.2E-9 T 12-10-2018 IPR000014 PAS domain AFR_26795 02497100ac16893dc988da5692da82fd 615 SUPERFAMILY SSF55785 485 597 7.09E-15 T 12-10-2018 IPR035965 PAS domain superfamily AFR_26795 02497100ac16893dc988da5692da82fd 615 Pfam PF00989 PAS fold 498 595 1.5E-8 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_26795 02497100ac16893dc988da5692da82fd 615 SUPERFAMILY SSF55785 298 406 1.61E-10 T 12-10-2018 IPR035965 PAS domain superfamily AFR_26795 02497100ac16893dc988da5692da82fd 615 SMART SM00138 5 266 1.9E-77 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_26795 02497100ac16893dc988da5692da82fd 615 Gene3D G3DSA:3.40.50.150 70 268 1.6E-58 T 12-10-2018 AFR_26795 02497100ac16893dc988da5692da82fd 615 Pfam PF03705 CheR methyltransferase, all-alpha domain 7 58 1.3E-16 T 12-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AFR_05730 4d63e1ee023b0e2f98c126899b41fef9 318 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 7 287 1.7E-39 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_05730 4d63e1ee023b0e2f98c126899b41fef9 318 Gene3D G3DSA:1.20.1510.10 7 219 2.9E-32 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_05730 4d63e1ee023b0e2f98c126899b41fef9 318 Gene3D G3DSA:3.30.70.1350 221 301 1.7E-5 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFR_05730 4d63e1ee023b0e2f98c126899b41fef9 318 SUPERFAMILY SSF161111 6 220 4.32E-36 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_05730 4d63e1ee023b0e2f98c126899b41fef9 318 Pfam PF01545 Cation efflux family 10 219 1.4E-33 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_05730 4d63e1ee023b0e2f98c126899b41fef9 318 SUPERFAMILY SSF160240 223 296 8.37E-10 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFR_30390 b1e0243807cdc67ae17bb2d935ef4648 293 Pfam PF00005 ABC transporter 23 162 3.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_30390 b1e0243807cdc67ae17bb2d935ef4648 293 SUPERFAMILY SSF52540 7 225 4.09E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30390 b1e0243807cdc67ae17bb2d935ef4648 293 Gene3D G3DSA:3.40.50.300 4 234 1.1E-59 T 12-10-2018 AFR_30390 b1e0243807cdc67ae17bb2d935ef4648 293 SMART SM00382 32 210 2.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 SUPERFAMILY SSF56091 4 192 8.63E-40 T 12-10-2018 AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 9 310 2.8E-71 T 12-10-2018 IPR014146 DNA ligase D, ligase domain AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 Gene3D G3DSA:3.30.470.30 30 149 2.0E-48 T 12-10-2018 AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 SUPERFAMILY SSF50249 196 313 9.14E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 Pfam PF01068 ATP dependent DNA ligase domain 19 192 1.4E-23 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 Gene3D G3DSA:3.30.1490.70 18 190 2.0E-48 T 12-10-2018 AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 Pfam PF04679 ATP dependent DNA ligase C terminal region 209 304 2.2E-21 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AFR_02060 f02120ef0a17f8a59d1eb3f27bd57520 317 Gene3D G3DSA:2.40.50.140 194 312 7.4E-33 T 12-10-2018 AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 177 5.3E-39 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 Gene3D G3DSA:3.40.50.970 358 580 1.0E-59 T 12-10-2018 AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 SUPERFAMILY SSF52467 191 339 7.06E-39 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 SUPERFAMILY SSF52518 364 547 2.75E-55 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 325 7.3E-29 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 533 4.7E-38 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 Gene3D G3DSA:3.40.50.970 8 182 3.0E-51 T 12-10-2018 AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 SUPERFAMILY SSF52518 8 177 3.83E-39 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_14180 77f4b9a28e09a6dfce889e8dd04c1d75 583 Gene3D G3DSA:3.40.50.1220 188 338 4.8E-42 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PIRSF PIRSF000350 1 460 2.7E-72 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 7.9E-36 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 7.9E-36 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 7.9E-36 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.9E-36 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 7.9E-36 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 SUPERFAMILY SSF51905 3 337 2.79E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 SUPERFAMILY SSF55424 347 461 5.84E-29 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 1.5E-56 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 Gene3D G3DSA:3.30.390.30 341 462 1.1E-36 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 456 5.8E-24 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 Gene3D G3DSA:3.50.50.60 4 331 4.5E-101 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.2E-51 T 12-10-2018 AFR_39420 fb6e6903aa0d6e0d5726e6c9d79f687b 466 Gene3D G3DSA:3.50.50.60 155 273 4.5E-101 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_30505 d7eb31cc3b879c7873affe0897caed0e 157 SUPERFAMILY SSF52121 10 155 2.49E-45 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30505 d7eb31cc3b879c7873affe0897caed0e 157 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 16 149 1.2E-43 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30505 d7eb31cc3b879c7873affe0897caed0e 157 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 24.226 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30505 d7eb31cc3b879c7873affe0897caed0e 157 Gene3D G3DSA:3.40.50.960 2 156 2.1E-48 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30505 d7eb31cc3b879c7873affe0897caed0e 157 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 149 4.7E-36 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PIRSF PIRSF000532 1 339 5.3E-122 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 SUPERFAMILY SSF53784 1 331 1.83E-119 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 Pfam PF00365 Phosphofructokinase 2 296 1.3E-104 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 320 4.4E-151 T 12-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 Gene3D G3DSA:3.40.50.450 3 320 4.0E-113 T 12-10-2018 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 Gene3D G3DSA:3.40.50.460 140 277 4.0E-113 T 12-10-2018 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 44.072 T 12-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_09625 ed28dca0657c42f3ce97239293ca6b47 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.8E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 Gene3D G3DSA:3.30.190.20 24 225 8.8E-81 T 12-10-2018 AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 Pfam PF00687 Ribosomal protein L1p/L10e family 33 220 3.3E-50 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.25 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 Gene3D G3DSA:3.40.50.790 68 159 8.8E-81 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 SUPERFAMILY SSF56808 6 227 9.55E-81 T 12-10-2018 IPR023674 Ribosomal protein L1-like AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 4 227 1.7E-100 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04430 7ace560af4d74cf93bd1b024ad422501 239 PIRSF PIRSF002155 1 227 2.7E-75 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_23175 13ed72ba17ad1d2902bbed89886b280e 306 Gene3D G3DSA:3.40.50.720 1 306 1.9E-68 T 12-10-2018 AFR_23175 13ed72ba17ad1d2902bbed89886b280e 306 SUPERFAMILY SSF51735 9 249 1.21E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23175 13ed72ba17ad1d2902bbed89886b280e 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23175 13ed72ba17ad1d2902bbed89886b280e 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23175 13ed72ba17ad1d2902bbed89886b280e 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23175 13ed72ba17ad1d2902bbed89886b280e 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23175 13ed72ba17ad1d2902bbed89886b280e 306 Pfam PF00106 short chain dehydrogenase 16 220 1.2E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37640 934c9e859bf2ab9935626253a056001e 208 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 1.7E-20 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_37640 934c9e859bf2ab9935626253a056001e 208 SUPERFAMILY SSF51735 1 201 6.61E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37640 934c9e859bf2ab9935626253a056001e 208 Gene3D G3DSA:3.40.50.720 1 194 5.3E-53 T 12-10-2018 AFR_16220 bb0e0273681daa2268d0382bf867a856 277 SUPERFAMILY SSF52540 11 239 1.7E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16220 bb0e0273681daa2268d0382bf867a856 277 Gene3D G3DSA:3.40.50.300 1 249 1.1E-56 T 12-10-2018 AFR_16220 bb0e0273681daa2268d0382bf867a856 277 SMART SM00382 37 227 8.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_16220 bb0e0273681daa2268d0382bf867a856 277 Pfam PF00005 ABC transporter 28 179 1.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 SUPERFAMILY SSF49899 37 277 1.21E-75 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 Gene3D G3DSA:2.80.10.50 288 378 1.0E-27 T 12-10-2018 AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 Gene3D G3DSA:2.80.10.50 379 412 5.1E-8 T 12-10-2018 AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 Pfam PF00652 Ricin-type beta-trefoil lectin domain 289 410 8.8E-25 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 SMART SM00458 287 413 1.8E-25 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 Gene3D G3DSA:2.60.120.200 36 282 3.9E-92 T 12-10-2018 AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 SUPERFAMILY SSF50370 282 411 3.93E-36 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_38190 c3e8c0f4ae84ab84bc9d1601008679ac 413 Pfam PF00722 Glycosyl hydrolases family 16 68 271 1.0E-41 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 Gene3D G3DSA:3.40.50.300 44 191 1.5E-22 T 12-10-2018 AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 SUPERFAMILY SSF52317 251 447 3.3E-26 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 4 439 41.166 T 12-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 Gene3D G3DSA:3.40.50.880 254 407 2.3E-6 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 191 1.1E-21 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 Gene3D G3DSA:3.40.50.300 7 43 1.1E-5 T 12-10-2018 AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 SUPERFAMILY SSF52540 5 197 1.0E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 449 2.2E-118 T 12-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AFR_26915 4422a5bab50bca8d33b9816f2b7dfe9c 452 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 438 2.3E-20 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 SUPERFAMILY SSF56059 6 382 5.53E-128 T 12-10-2018 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Gene3D G3DSA:3.30.470.20 247 344 3.8E-36 T 12-10-2018 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 SUPERFAMILY SSF52009 386 510 1.83E-34 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 7 885 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 PIRSF PIRSF000853 5 893 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 299 356 1.5E-8 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 290 5.8E-39 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Gene3D G3DSA:1.20.80.30 111 205 1.8E-96 T 12-10-2018 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Gene3D G3DSA:1.10.189.10 348 520 3.0E-62 T 12-10-2018 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Pfam PF00391 PEP-utilising enzyme, mobile domain 423 502 1.3E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 533 881 1.5E-83 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 SUPERFAMILY SSF51621 532 884 1.35E-112 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Gene3D G3DSA:3.30.1490.20 19 246 1.8E-96 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Gene3D G3DSA:3.20.20.60 544 885 5.2E-137 T 12-10-2018 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 451 462 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AFR_33180 c4d0e935c0e3290b485bc4cbbf9f4d2b 893 Gene3D G3DSA:3.50.30.10 386 506 3.0E-62 T 12-10-2018 AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 Gene3D G3DSA:3.30.420.10 4 140 6.0E-42 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 Gene3D G3DSA:3.40.50.1240 167 370 1.6E-56 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 SUPERFAMILY SSF53254 168 369 2.63E-54 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 SUPERFAMILY SSF53098 6 130 2.53E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 170 364 2.0E-55 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 Pfam PF13456 Reverse transcriptase-like 10 132 1.3E-27 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 SMART SM00855 169 325 4.0E-20 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_08900 c789be5ec03d3abfb8d86dd6d8b20adf 370 PIRSF PIRSF036922 2 370 5.0E-140 T 12-10-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing AFR_15275 19bb90a21e1b87ac772f192eac085147 266 Gene3D G3DSA:3.40.50.1820 1 265 1.7E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15275 19bb90a21e1b87ac772f192eac085147 266 Pfam PF00561 alpha/beta hydrolase fold 22 170 1.9E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15275 19bb90a21e1b87ac772f192eac085147 266 SUPERFAMILY SSF53474 2 264 1.62E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15275 19bb90a21e1b87ac772f192eac085147 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15275 19bb90a21e1b87ac772f192eac085147 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15275 19bb90a21e1b87ac772f192eac085147 266 PRINTS PR00412 Epoxide hydrolase signature 244 266 7.6E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_15275 19bb90a21e1b87ac772f192eac085147 266 PRINTS PR00412 Epoxide hydrolase signature 28 46 7.6E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_15275 19bb90a21e1b87ac772f192eac085147 266 PRINTS PR00412 Epoxide hydrolase signature 105 118 7.6E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 1.3E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 1.3E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 1.3E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 SMART SM00387 311 415 2.1E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 Gene3D G3DSA:3.30.565.10 276 415 2.2E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 SUPERFAMILY SSF55874 261 413 5.24E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 414 1.5E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 SMART SM00388 208 271 1.6E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 271 4.2E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 Gene3D G3DSA:1.10.287.130 195 270 1.3E-8 T 12-10-2018 AFR_28215 9d2bb8aaf67966273ce0a90eb36c0ccc 415 SUPERFAMILY SSF47384 197 270 1.16E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_14855 ae63764780ef0fa3dde84710c530d2d6 216 Gene3D G3DSA:2.30.110.10 36 167 6.4E-13 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_14855 ae63764780ef0fa3dde84710c530d2d6 216 SUPERFAMILY SSF50475 42 147 2.36E-11 T 12-10-2018 AFR_14855 ae63764780ef0fa3dde84710c530d2d6 216 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 135 3.0E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_12520 1f739eacc547df0498e1445ebc87ee00 268 Pfam PF00561 alpha/beta hydrolase fold 30 136 1.9E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_12520 1f739eacc547df0498e1445ebc87ee00 268 SUPERFAMILY SSF53474 6 200 1.19E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12520 1f739eacc547df0498e1445ebc87ee00 268 Gene3D G3DSA:3.40.50.1820 9 258 1.6E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 ProSitePatterns PS01125 ROK family signature. 216 243 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 Gene3D G3DSA:3.30.420.40 79 210 9.0E-28 T 12-10-2018 AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 SUPERFAMILY SSF46785 10 70 5.35E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 SUPERFAMILY SSF53067 84 354 5.49E-36 T 12-10-2018 AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 Pfam PF00480 ROK family 93 264 5.6E-28 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 Gene3D G3DSA:3.30.420.40 269 355 2.6E-8 T 12-10-2018 AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 Gene3D G3DSA:1.10.10.10 1 77 1.8E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 SMART SM00419 21 70 0.001 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFR_20500 93dd76c0243449800df22230ecb1f1a1 364 Gene3D G3DSA:3.30.420.40 211 268 3.3E-18 T 12-10-2018 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 361 2.2E-130 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 Pfam PF06071 Protein of unknown function (DUF933) 277 360 3.9E-38 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 Pfam PF01926 50S ribosome-binding GTPase 5 124 1.5E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 Gene3D G3DSA:3.10.20.30 48 359 1.4E-137 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 361 42.046 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 SUPERFAMILY SSF52540 3 299 1.94E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 SUPERFAMILY SSF81271 277 361 1.11E-34 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 PIRSF PIRSF006641 1 361 1.5E-137 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 Gene3D G3DSA:1.10.150.300 113 200 1.4E-137 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 8.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 8.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 8.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 8.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_39115 61b1260c5a2d9a551d0d43781d8b746a 361 Gene3D G3DSA:3.40.50.300 3 276 1.4E-137 T 12-10-2018 AFR_30435 2a62d56e23e48b26c25c0ac786a4d939 255 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 3 180 2.8E-8 T 12-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase AFR_30435 2a62d56e23e48b26c25c0ac786a4d939 255 SUPERFAMILY SSF102522 2 145 2.62E-6 T 12-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AFR_41390 bda6c3d44a19c5228092da46c3f651d8 277 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 69 1.6E-8 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_41390 bda6c3d44a19c5228092da46c3f651d8 277 Hamap MF_00158 Pantothenate synthetase [panC]. 3 271 37.919 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFR_41390 bda6c3d44a19c5228092da46c3f651d8 277 Gene3D G3DSA:3.30.1300.10 176 277 6.5E-36 T 12-10-2018 AFR_41390 bda6c3d44a19c5228092da46c3f651d8 277 Pfam PF02569 Pantoate-beta-alanine ligase 6 269 2.3E-93 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFR_41390 bda6c3d44a19c5228092da46c3f651d8 277 SUPERFAMILY SSF52374 7 273 6.7E-96 T 12-10-2018 AFR_41390 bda6c3d44a19c5228092da46c3f651d8 277 Gene3D G3DSA:3.40.50.620 1 175 5.0E-69 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_41390 bda6c3d44a19c5228092da46c3f651d8 277 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 17 269 3.9E-79 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFR_17475 006ed21a05fea5293de18486f3a74863 556 Pfam PF00266 Aminotransferase class-V 29 404 1.5E-32 T 12-10-2018 IPR000192 Aminotransferase class V domain AFR_17475 006ed21a05fea5293de18486f3a74863 556 Gene3D G3DSA:3.40.640.10 45 277 2.2E-40 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_17475 006ed21a05fea5293de18486f3a74863 556 SUPERFAMILY SSF53383 19 453 1.73E-61 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_17475 006ed21a05fea5293de18486f3a74863 556 Gene3D G3DSA:3.90.1150.10 297 459 4.2E-20 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_37345 909b79898d2931edfb57668506bf7227 550 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 48.427 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37345 909b79898d2931edfb57668506bf7227 550 SUPERFAMILY SSF50615 15 97 7.32E-24 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37345 909b79898d2931edfb57668506bf7227 550 SUPERFAMILY SSF52540 99 381 6.58E-96 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37345 909b79898d2931edfb57668506bf7227 550 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 4.1E-44 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37345 909b79898d2931edfb57668506bf7227 550 Gene3D G3DSA:3.40.50.300 97 382 3.5E-118 T 12-10-2018 AFR_37345 909b79898d2931edfb57668506bf7227 550 Gene3D G3DSA:1.20.150.20 383 513 3.6E-45 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37345 909b79898d2931edfb57668506bf7227 550 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 511 2.1E-238 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37345 909b79898d2931edfb57668506bf7227 550 Gene3D G3DSA:2.40.30.20 4 96 1.4E-27 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37345 909b79898d2931edfb57668506bf7227 550 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37345 909b79898d2931edfb57668506bf7227 550 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 4.9E-67 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_37345 909b79898d2931edfb57668506bf7227 550 SUPERFAMILY SSF47917 384 511 2.41E-44 T 12-10-2018 AFR_37345 909b79898d2931edfb57668506bf7227 550 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 1.1E-14 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF56801 471 1030 1.96E-155 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:1.10.1200.10 3559 3638 7.5E-25 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 1725 1991 6.11E-56 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF47336 5061 5132 4.84E-20 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00550 Phosphopantetheine attachment site 5071 5130 3.4E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00550 Phosphopantetheine attachment site 6116 6176 3.3E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00550 Phosphopantetheine attachment site 1021 1079 6.5E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00550 Phosphopantetheine attachment site 2521 2581 1.0E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00550 Phosphopantetheine attachment site 3573 3633 4.0E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 5153 5324 1.33E-49 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 6381 6633 5.56E-38 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:1.10.1200.10 2506 2589 1.1E-23 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:1.10.1200.10 5055 5138 2.6E-27 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 4123 4300 4.11E-41 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00455 Putative AMP-binding domain signature. 653 664 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 2788 3027 5.34E-66 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 4302 4554 2.5E-128 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 4302 4545 6.45E-57 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 1541 1740 6.37E-41 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.40.50.12780 4568 4952 2.3E-145 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.40.50.12780 3053 3455 1.9E-123 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.40.50.12780 1994 2401 1.4E-127 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.40.50.12780 499 901 1.8E-133 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.40.50.12780 5595 5995 6.6E-134 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 1094 1253 2.89E-31 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 2606 2780 4.78E-50 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 236 499 1.07E-61 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 5332 5571 8.12E-68 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 3820 4087 1.3E-78 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 1249 1511 1.8E-79 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 6365 6636 4.3E-75 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 1547 1916 1.0E-127 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5628 6025 2.4E-128 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4602 4982 2.0E-129 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 532 932 3.3E-123 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3084 3485 1.6E-114 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2025 2431 1.2E-111 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4702 4713 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.300.30 3456 3556 1.4E-33 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.300.30 902 1011 1.0E-37 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.300.30 4953 5054 2.3E-37 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2542 2557 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 1726 1981 1.0E-127 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3201 3212 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2149 2160 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF47336 3564 3635 2.22E-18 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 2605 2973 1.1E-155 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF56801 4540 5081 2.49E-163 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 57 421 3.8E-147 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:1.10.1200.10 1012 1086 1.3E-23 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 1265 1510 1.78E-44 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 2604 3042 1.3E-103 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 56 489 1.9E-100 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 5150 5588 1.2E-104 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 1541 1980 5.6E-84 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 3651 4089 8.1E-70 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 6193 6634 2.9E-66 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 1098 1511 3.9E-57 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00668 Condensation domain 4117 4553 9.0E-83 T 12-10-2018 IPR001242 Condensation domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3595 3610 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00501 AMP-binding enzyme 5607 6001 2.6E-91 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00501 AMP-binding enzyme 512 908 8.9E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00501 AMP-binding enzyme 3064 3461 1.7E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00501 AMP-binding enzyme 4582 4957 4.9E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF00501 AMP-binding enzyme 2004 2407 2.5E-89 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 5328 5573 1.1E-158 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF47336 2512 2583 1.16E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1384 1533 3.8E-35 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3958 4110 1.3E-39 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 6504 6635 1.5E-25 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF56801 3024 3583 3.79E-139 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 6197 6373 2.78E-39 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF47336 1011 1082 7.33E-18 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SMART SM00823 Phosphopantetheine attachment site 6114 6182 0.014 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SMART SM00823 Phosphopantetheine attachment site 1018 1086 0.0039 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SMART SM00823 Phosphopantetheine attachment site 5068 5137 2.1E-10 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SMART SM00823 Phosphopantetheine attachment site 3571 3639 0.0019 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SMART SM00823 Phosphopantetheine attachment site 2518 2587 1.4E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.300.30 5996 6098 1.6E-36 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.300.30 2402 2505 1.6E-30 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF56801 5566 6127 2.75E-154 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 5152 5517 1.1E-158 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 232 477 3.8E-147 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 6184 6363 6.2E-56 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 3639 3816 2.3E-52 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 1087 1248 2.1E-43 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 3836 4086 6.11E-42 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF47336 6107 6178 1.57E-18 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.30 2784 3029 1.1E-155 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF13193 AMP-binding enzyme C-terminal domain 4966 5041 7.5E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF13193 AMP-binding enzyme C-terminal domain 3469 3544 2.6E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF13193 AMP-binding enzyme C-terminal domain 916 991 8.7E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF13193 AMP-binding enzyme C-terminal domain 2415 2491 1.1E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Pfam PF13193 AMP-binding enzyme C-terminal domain 6009 6085 9.3E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 54 248 5.34E-50 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5754 5765 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF56801 1963 2530 2.62E-140 T 12-10-2018 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:3.30.559.10 4123 4493 2.5E-128 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5092 5107 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1042 1057 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 Gene3D G3DSA:1.10.1200.10 6100 6183 1.5E-24 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12415 5a18a67514cc7ba131311fe297b3d063 6637 SUPERFAMILY SSF52777 3649 3848 1.09E-38 T 12-10-2018 AFR_38685 c238d72234def1ba3f8797f8b1b4df14 240 ProSitePatterns PS00307 Legume lectins beta-chain signature. 127 133 - T 12-10-2018 IPR019825 Legume lectin, beta chain, Mn/Ca-binding site Reactome: R-HSA-196791|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-975634 AFR_38685 c238d72234def1ba3f8797f8b1b4df14 240 Gene3D G3DSA:2.60.120.200 32 240 1.1E-47 T 12-10-2018 AFR_38685 c238d72234def1ba3f8797f8b1b4df14 240 Pfam PF00139 Legume lectin domain 34 237 2.3E-26 T 12-10-2018 IPR001220 Legume lectin domain GO:0030246 AFR_38685 c238d72234def1ba3f8797f8b1b4df14 240 SUPERFAMILY SSF49899 36 237 2.66E-39 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_05275 1da49df157b600c4e3af9c09bb7d4383 643 SUPERFAMILY SSF81296 544 642 2.66E-19 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_05275 1da49df157b600c4e3af9c09bb7d4383 643 Pfam PF09118 Domain of unknown function (DUF1929) 548 642 5.2E-21 T 12-10-2018 IPR015202 Galactose oxidase-like, Early set domain AFR_05275 1da49df157b600c4e3af9c09bb7d4383 643 Gene3D G3DSA:2.60.40.10 549 643 2.5E-24 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_05275 1da49df157b600c4e3af9c09bb7d4383 643 SUPERFAMILY SSF50965 257 545 4.84E-31 T 12-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller AFR_05275 1da49df157b600c4e3af9c09bb7d4383 643 Gene3D G3DSA:2.130.10.80 184 548 2.8E-56 T 12-10-2018 IPR037293 Galactose oxidase, central domain superfamily AFR_05275 1da49df157b600c4e3af9c09bb7d4383 643 Gene3D G3DSA:2.130.10.80 46 181 1.9E-14 T 12-10-2018 IPR037293 Galactose oxidase, central domain superfamily AFR_05275 1da49df157b600c4e3af9c09bb7d4383 643 SUPERFAMILY SSF50965 15 136 1.09E-5 T 12-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller AFR_37410 77fc9351397bc22d6ef32955a54a5d63 501 SMART SM00267 344 501 1.1E-12 T 12-10-2018 IPR000160 GGDEF domain AFR_37410 77fc9351397bc22d6ef32955a54a5d63 501 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 354 463 6.8E-21 T 12-10-2018 IPR000160 GGDEF domain AFR_37410 77fc9351397bc22d6ef32955a54a5d63 501 Gene3D G3DSA:1.25.40.10 11 202 8.4E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_37410 77fc9351397bc22d6ef32955a54a5d63 501 Gene3D G3DSA:3.30.70.270 349 498 1.1E-31 T 12-10-2018 AFR_37410 77fc9351397bc22d6ef32955a54a5d63 501 Pfam PF00990 Diguanylate cyclase, GGDEF domain 356 487 1.9E-24 T 12-10-2018 IPR000160 GGDEF domain AFR_37410 77fc9351397bc22d6ef32955a54a5d63 501 SUPERFAMILY SSF55073 360 494 4.32E-26 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_05030 c72d633748443b6a31a7db2037132a49 536 Gene3D G3DSA:3.40.190.10 38 521 7.7E-105 T 12-10-2018 AFR_05030 c72d633748443b6a31a7db2037132a49 536 SUPERFAMILY SSF53850 33 532 2.35E-99 T 12-10-2018 AFR_05030 c72d633748443b6a31a7db2037132a49 536 Gene3D G3DSA:3.10.105.10 297 508 7.7E-105 T 12-10-2018 AFR_05030 c72d633748443b6a31a7db2037132a49 536 PIRSF PIRSF002741 1 534 3.1E-78 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFR_05030 c72d633748443b6a31a7db2037132a49 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 457 9.8E-60 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFR_05030 c72d633748443b6a31a7db2037132a49 536 Gene3D G3DSA:3.90.76.10 59 193 7.7E-105 T 12-10-2018 AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 Pfam PF03704 Bacterial transcriptional activator domain 94 236 1.5E-24 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 Gene3D G3DSA:1.25.40.10 91 264 1.1E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 SUPERFAMILY SSF48452 91 257 9.48E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 Gene3D G3DSA:1.10.10.10 1 89 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 SMART SM00862 11 87 1.7E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 Pfam PF00722 Glycosyl hydrolases family 16 380 524 2.6E-6 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 SMART SM01043 94 236 2.2E-31 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 SUPERFAMILY SSF49899 303 525 2.16E-14 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 Pfam PF00486 Transcriptional regulatory protein, C terminal 16 87 4.3E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 Gene3D G3DSA:2.60.120.200 310 527 2.2E-17 T 12-10-2018 AFR_13795 f5f2a880dc49a09494d0c8f02aafeaa1 527 SUPERFAMILY SSF46894 2 87 3.4E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_11620 18263c25cdd87f522a0e1565924d15db 668 Gene3D G3DSA:3.40.50.720 168 293 1.2E-28 T 12-10-2018 AFR_11620 18263c25cdd87f522a0e1565924d15db 668 SUPERFAMILY SSF51735 169 299 3.94E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11620 18263c25cdd87f522a0e1565924d15db 668 Pfam PF02719 Polysaccharide biosynthesis protein 312 588 4.7E-100 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain AFR_11620 18263c25cdd87f522a0e1565924d15db 668 Pfam PF13727 CoA-binding domain 92 267 1.3E-16 T 12-10-2018 AFR_11620 18263c25cdd87f522a0e1565924d15db 668 Gene3D G3DSA:3.40.50.720 307 591 2.0E-100 T 12-10-2018 AFR_11620 18263c25cdd87f522a0e1565924d15db 668 SUPERFAMILY SSF51735 309 568 1.43E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 Pfam PF00072 Response regulator receiver domain 3 112 6.6E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 Gene3D G3DSA:3.40.50.2300 1 122 4.6E-30 T 12-10-2018 AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 SUPERFAMILY SSF46894 121 217 9.92E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 SMART SM00862 145 217 2.3E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 SMART SM00448 1 112 2.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 Gene3D G3DSA:1.10.10.10 123 219 3.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 SUPERFAMILY SSF52172 2 118 1.71E-29 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28220 dd4415e82440ce2b3a344955e5d59423 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 217 1.7E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_19775 41a047e822c02fa93a7993b72a9194f1 459 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 351 371 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFR_19775 41a047e822c02fa93a7993b72a9194f1 459 TIGRFAM TIGR03173 pbuX: xanthine permease 28 436 2.2E-147 T 12-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 AFR_19775 41a047e822c02fa93a7993b72a9194f1 459 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 21 433 5.8E-110 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFR_19775 41a047e822c02fa93a7993b72a9194f1 459 Pfam PF00860 Permease family 25 402 1.3E-99 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 AFR_17015 9f484c5c6f67e829cf6e2ab0e828e0ed 423 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_17015 9f484c5c6f67e829cf6e2ab0e828e0ed 423 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 130 142 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AFR_17015 9f484c5c6f67e829cf6e2ab0e828e0ed 423 SUPERFAMILY SSF56112 8 227 5.93E-51 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_17015 9f484c5c6f67e829cf6e2ab0e828e0ed 423 Gene3D G3DSA:1.10.510.10 2 232 4.3E-51 T 12-10-2018 AFR_17015 9f484c5c6f67e829cf6e2ab0e828e0ed 423 Pfam PF00069 Protein kinase domain 11 202 3.6E-30 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_38570 94071f6315698e0cf1e8f4fc126bceb8 353 Gene3D G3DSA:3.40.640.10 22 249 9.2E-65 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_38570 94071f6315698e0cf1e8f4fc126bceb8 353 Pfam PF01212 Beta-eliminating lyase 37 284 1.7E-28 T 12-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 AFR_38570 94071f6315698e0cf1e8f4fc126bceb8 353 SUPERFAMILY SSF53383 35 316 1.98E-61 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_38570 94071f6315698e0cf1e8f4fc126bceb8 353 Gene3D G3DSA:3.90.1150.10 253 351 3.1E-6 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_11160 05057c896321292a5de2c6bce4027772 375 Gene3D G3DSA:2.40.30.10 144 242 1.4E-16 T 12-10-2018 AFR_11160 05057c896321292a5de2c6bce4027772 375 PRINTS PR00410 Phenol hydroxylase reductase family signature 254 273 4.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_11160 05057c896321292a5de2c6bce4027772 375 PRINTS PR00410 Phenol hydroxylase reductase family signature 279 288 4.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_11160 05057c896321292a5de2c6bce4027772 375 PRINTS PR00410 Phenol hydroxylase reductase family signature 177 189 4.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_11160 05057c896321292a5de2c6bce4027772 375 PRINTS PR00410 Phenol hydroxylase reductase family signature 342 350 4.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_11160 05057c896321292a5de2c6bce4027772 375 Pfam PF00970 Oxidoreductase FAD-binding domain 175 242 1.2E-5 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFR_11160 05057c896321292a5de2c6bce4027772 375 Gene3D G3DSA:3.40.50.80 247 374 6.4E-23 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_11160 05057c896321292a5de2c6bce4027772 375 SUPERFAMILY SSF52343 247 373 4.71E-25 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_11160 05057c896321292a5de2c6bce4027772 375 Gene3D G3DSA:1.10.490.10 19 143 5.6E-12 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFR_11160 05057c896321292a5de2c6bce4027772 375 SUPERFAMILY SSF63380 150 239 1.97E-18 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_11160 05057c896321292a5de2c6bce4027772 375 Pfam PF00175 Oxidoreductase NAD-binding domain 255 355 2.1E-10 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_11160 05057c896321292a5de2c6bce4027772 375 SUPERFAMILY SSF46458 29 144 1.65E-10 T 12-10-2018 IPR009050 Globin-like superfamily AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 Gene3D G3DSA:3.30.70.270 352 519 8.9E-47 T 12-10-2018 AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 Pfam PF00990 Diguanylate cyclase, GGDEF domain 367 516 1.5E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 517 1.8E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 SMART SM00267 355 519 1.9E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 SUPERFAMILY SSF48452 185 360 8.35E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 SUPERFAMILY SSF55073 371 517 1.78E-37 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 Gene3D G3DSA:1.25.40.10 19 328 1.0E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02340 88853775b2c75d842f5e868642dd4fdb 519 SUPERFAMILY SSF48452 31 214 2.9E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 Pfam PF00106 short chain dehydrogenase 6 204 4.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 Gene3D G3DSA:3.40.50.720 1 243 1.0E-67 T 12-10-2018 AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20035 efa1c89b6f7cb945e84762a8fd2b2dbe 243 SUPERFAMILY SSF51735 5 235 2.7E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_39620 1563f9dc8e2bf17bf6ba3d60106b802d 177 SUPERFAMILY SSF55144 7 175 5.62E-26 T 12-10-2018 IPR009097 Cyclic phosphodiesterase AFR_39620 1563f9dc8e2bf17bf6ba3d60106b802d 177 Gene3D G3DSA:3.90.1140.10 7 175 1.0E-26 T 12-10-2018 AFR_39620 1563f9dc8e2bf17bf6ba3d60106b802d 177 Pfam PF13563 2'-5' RNA ligase superfamily 17 159 3.6E-20 T 12-10-2018 AFR_26445 19320b19f393a6549c3857ea606bcf01 313 Pfam PF12705 PD-(D/E)XK nuclease superfamily 23 280 2.4E-35 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AFR_26445 19320b19f393a6549c3857ea606bcf01 313 Gene3D G3DSA:3.90.320.10 131 282 1.8E-5 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFR_26445 19320b19f393a6549c3857ea606bcf01 313 SUPERFAMILY SSF52980 50 213 1.13E-6 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_15730 2d490cdc68341c77474e61f9059c3777 487 SUPERFAMILY SSF51905 7 250 7.56E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_15730 2d490cdc68341c77474e61f9059c3777 487 Gene3D G3DSA:3.50.50.60 311 484 3.3E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_15730 2d490cdc68341c77474e61f9059c3777 487 Gene3D G3DSA:3.50.50.60 2 181 1.1E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_15730 2d490cdc68341c77474e61f9059c3777 487 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 212 3.0E-15 T 12-10-2018 AFR_15730 2d490cdc68341c77474e61f9059c3777 487 SUPERFAMILY SSF51905 278 454 1.88E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_15730 2d490cdc68341c77474e61f9059c3777 487 PRINTS PR00419 Adrenodoxin reductase family signature 9 31 2.5E-5 T 12-10-2018 AFR_15730 2d490cdc68341c77474e61f9059c3777 487 PRINTS PR00419 Adrenodoxin reductase family signature 174 188 2.5E-5 T 12-10-2018 AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 SUPERFAMILY SSF46785 541 582 5.85E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 Pfam PF09106 Elongation factor SelB, winged helix 416 451 5.3E-6 T 12-10-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 3 341 1.9E-73 T 12-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 SUPERFAMILY SSF52540 3 190 2.44E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 Gene3D G3DSA:1.10.10.10 528 584 1.1E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 Gene3D G3DSA:3.40.50.300 3 169 3.6E-36 T 12-10-2018 AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 Pfam PF09107 Elongation factor SelB, winged helix 538 581 4.9E-13 T 12-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 Pfam PF00009 Elongation factor Tu GTP binding domain 4 162 1.2E-18 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 Gene3D G3DSA:2.40.30.10 170 278 3.1E-24 T 12-10-2018 AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 SUPERFAMILY SSF50447 170 262 8.64E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_27945 852c1a1a1a249163ec5beee1b94eebd7 589 Pfam PF03144 Elongation factor Tu domain 2 189 257 4.8E-8 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFR_01170 c379b4c6f0c8006479b5b1fea7d3149e 149 Gene3D G3DSA:1.10.10.60 1 67 1.5E-22 T 12-10-2018 AFR_01170 c379b4c6f0c8006479b5b1fea7d3149e 149 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 2.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01170 c379b4c6f0c8006479b5b1fea7d3149e 149 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01170 c379b4c6f0c8006479b5b1fea7d3149e 149 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 7.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01170 c379b4c6f0c8006479b5b1fea7d3149e 149 SUPERFAMILY SSF46689 2 81 2.99E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_34275 cc787e399c508f057a3e5e41af042539 543 Gene3D G3DSA:2.130.10.130 316 488 3.7E-18 T 12-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 Gene3D G3DSA:2.130.10.130 38 161 1.4E-6 T 12-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 Gene3D G3DSA:2.130.10.130 162 315 5.0E-18 T 12-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SUPERFAMILY SSF69318 317 488 3.14E-19 T 12-10-2018 AFR_34275 cc787e399c508f057a3e5e41af042539 543 Pfam PF01839 FG-GAP repeat 386 410 2.4E-5 T 12-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 Pfam PF01839 FG-GAP repeat 173 197 5.4E-6 T 12-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SUPERFAMILY SSF69318 49 268 8.37E-25 T 12-10-2018 AFR_34275 cc787e399c508f057a3e5e41af042539 543 PRINTS PR01185 Integrin alpha subunit signature 166 186 6.5E-5 T 12-10-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 PRINTS PR01185 Integrin alpha subunit signature 241 265 6.5E-5 T 12-10-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SMART SM00191 314 370 4.2 T 12-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SMART SM00191 382 447 0.0015 T 12-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SMART SM00191 98 157 0.3 T 12-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SMART SM00191 239 299 0.066 T 12-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SMART SM00191 169 227 0.17 T 12-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 AFR_34275 cc787e399c508f057a3e5e41af042539 543 SMART SM00191 460 525 24.0 T 12-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 Pfam PF03719 Ribosomal protein S5, C-terminal domain 113 184 2.8E-29 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 4 190 34.129 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 39 190 6.0E-66 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 ProSitePatterns PS00585 Ribosomal protein S5 signature. 55 87 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 SUPERFAMILY SSF54211 107 185 2.3E-25 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 Gene3D G3DSA:3.30.230.10 104 193 1.3E-34 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 Pfam PF00333 Ribosomal protein S5, N-terminal domain 40 102 5.7E-27 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 SUPERFAMILY SSF54768 37 103 1.15E-21 T 12-10-2018 AFR_04590 3984e95a2a861e20e72fbb678dc5a302 206 Gene3D G3DSA:3.30.160.20 32 99 3.3E-28 T 12-10-2018 AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 Gene3D G3DSA:1.25.40.10 94 252 4.9E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 Gene3D G3DSA:1.10.10.10 1 91 9.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 SUPERFAMILY SSF48452 93 249 1.37E-29 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 SUPERFAMILY SSF46894 2 78 1.84E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 SMART SM01043 96 241 5.2E-41 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 78 2.7E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 SMART SM00862 16 89 2.6E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_18400 a95232c9ce78b83410750ab1ec1a74b8 253 Pfam PF03704 Bacterial transcriptional activator domain 96 241 3.1E-35 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 305 6.4E-138 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 Gene3D G3DSA:3.40.50.720 5 305 1.8E-126 T 12-10-2018 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 118 1.2E-11 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 SUPERFAMILY SSF51735 3 153 4.16E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 SMART SM00859 5 121 3.0E-11 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 306 140.391 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 SUPERFAMILY SSF55347 129 286 2.62E-62 T 12-10-2018 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 PIRSF PIRSF015689 1 306 2.6E-128 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 129 286 2.2E-63 T 12-10-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFR_23750 5bf3219bb8f888bc2ae2998a8dd436ec 306 Gene3D G3DSA:3.30.360.10 129 286 1.8E-126 T 12-10-2018 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 PIRSF PIRSF005719 1 1193 9.4E-248 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 Gene3D G3DSA:3.40.50.300 1036 1192 1.1E-44 T 12-10-2018 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 629 9.0E-18 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 Gene3D G3DSA:3.30.70.1620 572 657 2.8E-19 T 12-10-2018 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 SUPERFAMILY SSF75553 495 671 1.57E-23 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1187 1.6E-277 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 SMART SM00968 512 630 4.2E-21 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 Gene3D G3DSA:1.20.1060.20 500 659 2.8E-19 T 12-10-2018 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 SUPERFAMILY SSF52540 2 1182 6.96E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1179 7.8E-71 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1189 22.002 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFR_36485 d40d4381894ff161c44fc6b8a99e8239 1193 Gene3D G3DSA:3.40.50.300 1 237 4.9E-55 T 12-10-2018 AFR_01270 56042e430212304c46e6153d3d7cb55e 187 SUPERFAMILY SSF53597 2 182 8.51E-33 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_01270 56042e430212304c46e6153d3d7cb55e 187 Gene3D G3DSA:3.40.430.10 2 186 1.9E-44 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_01270 56042e430212304c46e6153d3d7cb55e 187 Pfam PF01872 RibD C-terminal domain 5 174 1.3E-13 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 PIRSF PIRSF004640 13 373 2.1E-145 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 SUPERFAMILY SSF51717 27 220 4.47E-10 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 Pfam PF04551 GcpE protein 23 362 5.8E-133 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 368 33.507 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 Gene3D G3DSA:3.30.413.10 273 372 1.8E-35 T 12-10-2018 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 361 4.7E-129 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 SUPERFAMILY SSF56014 278 355 1.96E-12 T 12-10-2018 AFR_36140 6e32d5feaceb8e1fed7f9c7485850ad2 390 Gene3D G3DSA:3.20.20.20 14 272 1.1E-105 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 SUPERFAMILY SSF47384 225 314 7.26E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 463 4.5E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 SMART SM00387 356 466 9.7E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 SUPERFAMILY SSF55874 307 464 5.76E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 SUPERFAMILY SSF158472 191 238 6.93E-5 T 12-10-2018 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 SMART SM00304 188 241 5.3E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 Pfam PF00672 HAMP domain 188 238 6.1E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 Gene3D G3DSA:1.10.287.130 192 316 1.4E-18 T 12-10-2018 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 314 5.8E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 Gene3D G3DSA:3.30.565.10 319 468 4.5E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34120 74b0fc9b01fcb83676f601580e64a2d9 470 SMART SM00388 242 316 0.0028 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 Pfam PF13377 Periplasmic binding protein-like domain 170 324 1.1E-32 T 12-10-2018 AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 SMART SM00354 6 76 8.6E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 Gene3D G3DSA:1.10.260.40 2 64 5.6E-20 T 12-10-2018 AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 SUPERFAMILY SSF47413 6 64 6.82E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 Gene3D G3DSA:3.40.50.2300 74 316 1.1E-68 T 12-10-2018 AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 SUPERFAMILY SSF53822 69 327 3.34E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 Gene3D G3DSA:3.40.50.2300 162 322 1.1E-68 T 12-10-2018 AFR_20750 f6f26de4d1fcd64f807bfd451457607e 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 2.8E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 Pfam PF00072 Response regulator receiver domain 7 118 1.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 SUPERFAMILY SSF46894 144 217 7.14E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 SMART SM00421 154 211 1.2E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 Gene3D G3DSA:3.40.50.12740 5 217 6.8E-66 T 12-10-2018 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 4.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 4.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 4.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 SUPERFAMILY SSF52172 4 135 6.26E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 211 1.7E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21580 900cb4798e58988a77e07bb0d412bdbb 226 SMART SM00448 5 118 2.0E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_08605 1172f03f7cc4ad42e3363099bcc60981 360 Gene3D G3DSA:3.50.50.60 1 353 2.6E-102 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_08605 1172f03f7cc4ad42e3363099bcc60981 360 Pfam PF01494 FAD binding domain 3 311 3.7E-17 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_08605 1172f03f7cc4ad42e3363099bcc60981 360 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 8.7E-17 T 12-10-2018 AFR_08605 1172f03f7cc4ad42e3363099bcc60981 360 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 8.7E-17 T 12-10-2018 AFR_08605 1172f03f7cc4ad42e3363099bcc60981 360 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 8.7E-17 T 12-10-2018 AFR_08605 1172f03f7cc4ad42e3363099bcc60981 360 SUPERFAMILY SSF51905 1 352 1.5E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 SUPERFAMILY SSF141868 310 556 3.27E-84 T 12-10-2018 IPR035919 EAL domain superfamily AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 Gene3D G3DSA:3.20.20.450 309 561 3.8E-97 T 12-10-2018 IPR035919 EAL domain superfamily AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 SMART SM00267 125 295 6.6E-54 T 12-10-2018 IPR000160 GGDEF domain AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 Gene3D G3DSA:3.30.70.270 130 308 2.5E-53 T 12-10-2018 AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 Pfam PF00563 EAL domain 311 544 1.3E-74 T 12-10-2018 IPR001633 EAL domain AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 SUPERFAMILY SSF55073 141 296 4.55E-44 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 291 2.8E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 SMART SM00052 305 549 7.1E-108 T 12-10-2018 IPR001633 EAL domain AFR_06055 7d82ae9f84cf3fc343e9a9e1a1c48d59 562 Pfam PF00990 Diguanylate cyclase, GGDEF domain 136 289 2.4E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_00710 a4483135d7cbd8175c106448729d42d8 227 SUPERFAMILY SSF50494 16 225 2.85E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_00710 a4483135d7cbd8175c106448729d42d8 227 Gene3D G3DSA:2.40.10.10 102 225 1.7E-14 T 12-10-2018 AFR_00710 a4483135d7cbd8175c106448729d42d8 227 Gene3D G3DSA:2.40.10.10 34 101 7.9E-15 T 12-10-2018 AFR_00710 a4483135d7cbd8175c106448729d42d8 227 SMART SM00020 33 221 2.1E-12 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_00710 a4483135d7cbd8175c106448729d42d8 227 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 100 114 6.3E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_00710 a4483135d7cbd8175c106448729d42d8 227 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 179 191 6.3E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_00710 a4483135d7cbd8175c106448729d42d8 227 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 58 73 6.3E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_00710 a4483135d7cbd8175c106448729d42d8 227 Pfam PF00089 Trypsin 38 215 6.0E-27 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 60 65 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 Gene3D G3DSA:2.40.10.10 40 242 1.4E-65 T 12-10-2018 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 SMART SM00020 27 246 2.4E-58 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 Pfam PF00089 Trypsin 28 244 2.0E-48 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 Gene3D G3DSA:2.40.10.10 34 240 1.4E-65 T 12-10-2018 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 196 207 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 SUPERFAMILY SSF50494 25 251 6.34E-61 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 195 207 3.0E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 50 65 3.0E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_39240 2efe6eddda5b3bb368169fe78aa98b11 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 107 121 3.0E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_03540 2babe784fd37252e1c957144359ffa91 117 SMART SM00418 9 87 1.3E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_03540 2babe784fd37252e1c957144359ffa91 117 Pfam PF12840 Helix-turn-helix domain 8 67 2.3E-14 T 12-10-2018 AFR_03540 2babe784fd37252e1c957144359ffa91 117 Gene3D G3DSA:1.10.10.10 1 106 1.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03540 2babe784fd37252e1c957144359ffa91 117 SUPERFAMILY SSF46785 7 100 3.46E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 9.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 9.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 9.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15455 5df289de3818848b6f989eab698977b6 243 Gene3D G3DSA:3.40.50.720 1 243 2.2E-73 T 12-10-2018 AFR_15455 5df289de3818848b6f989eab698977b6 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 183 3.7E-5 T 12-10-2018 AFR_15455 5df289de3818848b6f989eab698977b6 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 4.4E-59 T 12-10-2018 AFR_15455 5df289de3818848b6f989eab698977b6 243 SUPERFAMILY SSF51735 4 242 2.28E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_05625 cedd1f027be15486b973e215a1366cb3 241 Gene3D G3DSA:3.40.50.12780 2 241 1.4E-8 T 12-10-2018 AFR_05625 cedd1f027be15486b973e215a1366cb3 241 Pfam PF00501 AMP-binding enzyme 12 86 1.2E-6 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_05625 cedd1f027be15486b973e215a1366cb3 241 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 9 237 3.9E-59 T 12-10-2018 IPR017523 Conserved hypothetical protein CHP03089 AFR_05625 cedd1f027be15486b973e215a1366cb3 241 SUPERFAMILY SSF56801 4 240 6.02E-20 T 12-10-2018 AFR_34845 f16499bd38e8abce050f9df6b1bca543 398 SUPERFAMILY SSF50891 287 395 1.37E-13 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_34845 f16499bd38e8abce050f9df6b1bca543 398 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 394 1.5E-80 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFR_34845 f16499bd38e8abce050f9df6b1bca543 398 SMART SM00797 24 398 3.5E-84 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFR_34845 f16499bd38e8abce050f9df6b1bca543 398 Gene3D G3DSA:2.40.100.10 284 397 4.2E-41 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 Pfam PF00072 Response regulator receiver domain 6 101 9.2E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 SMART SM00448 4 124 2.6E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 Gene3D G3DSA:3.40.50.2300 3 146 9.9E-22 T 12-10-2018 AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 198 4.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 SMART SM00421 150 213 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 Gene3D G3DSA:1.10.10.10 147 217 4.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 SUPERFAMILY SSF52172 2 178 7.35E-20 T 12-10-2018 IPR011006 CheY-like superfamily AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 5.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 5.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24195 8ea2bad917ab703a413f27995f7afbf6 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 5.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 SUPERFAMILY SSF52540 38 173 2.31E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 SMART SM00421 776 833 4.6E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 ProSitePatterns PS00622 LuxR-type HTH domain signature. 793 820 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 Pfam PF00196 Bacterial regulatory proteins, luxR family 778 830 8.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 779 793 5.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 793 809 5.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 809 821 5.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 SUPERFAMILY SSF46894 774 834 9.86E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 Gene3D G3DSA:1.10.10.10 753 837 2.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12480 511878a8d346ee5e60c78e5994075b9c 853 Gene3D G3DSA:1.25.40.10 344 589 5.5E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_36540 630faf76fac2bf38fcb0080f19d82a32 185 Pfam PF02620 Uncharacterized ACR, COG1399 70 182 1.0E-31 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD AFR_39680 dc11785093f701cfa862ee9f39517c6e 503 Gene3D G3DSA:3.20.20.80 18 381 8.8E-210 T 12-10-2018 AFR_39680 dc11785093f701cfa862ee9f39517c6e 503 SUPERFAMILY SSF51445 17 380 7.2E-109 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_39680 dc11785093f701cfa862ee9f39517c6e 503 SUPERFAMILY SSF51011 369 496 7.19E-31 T 12-10-2018 AFR_39680 dc11785093f701cfa862ee9f39517c6e 503 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 291 491 7.2E-37 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_39680 dc11785093f701cfa862ee9f39517c6e 503 SMART SM00813 291 491 1.4E-63 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_39680 dc11785093f701cfa862ee9f39517c6e 503 Gene3D G3DSA:2.60.40.1180 6 495 8.8E-210 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_34000 6f267370477209b416fca62f9840bcf2 247 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_34000 6f267370477209b416fca62f9840bcf2 247 SUPERFAMILY SSF53790 2 232 1.09E-60 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_34000 6f267370477209b416fca62f9840bcf2 247 Gene3D G3DSA:3.40.1010.10 1 110 6.3E-26 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_34000 6f267370477209b416fca62f9840bcf2 247 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 8.5E-40 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_34000 6f267370477209b416fca62f9840bcf2 247 Gene3D G3DSA:3.30.950.10 111 231 4.9E-41 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFR_34000 6f267370477209b416fca62f9840bcf2 247 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 243 2.1E-87 T 12-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 AFR_34000 6f267370477209b416fca62f9840bcf2 247 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_12340 90f59617f29e9e25af02b288537a7de9 245 Gene3D G3DSA:1.10.1660.10 6 244 6.5E-26 T 12-10-2018 AFR_12340 90f59617f29e9e25af02b288537a7de9 245 SMART SM00422 3 72 2.6E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_12340 90f59617f29e9e25af02b288537a7de9 245 Pfam PF13411 MerR HTH family regulatory protein 4 68 8.0E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_12340 90f59617f29e9e25af02b288537a7de9 245 SUPERFAMILY SSF46955 4 102 2.53E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_10235 459bae1888079864147a27bae0b314f1 429 Pfam PF13520 Amino acid permease 9 312 3.4E-37 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_10235 459bae1888079864147a27bae0b314f1 429 PIRSF PIRSF006060 3 411 3.9E-53 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_10235 459bae1888079864147a27bae0b314f1 429 Gene3D G3DSA:1.20.1740.10 5 411 4.0E-68 T 12-10-2018 AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 SUPERFAMILY SSF52172 154 229 1.14E-9 T 12-10-2018 IPR011006 CheY-like superfamily AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 SUPERFAMILY SSF55781 25 172 4.36E-21 T 12-10-2018 AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 SMART SM00065 25 172 3.8E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 Gene3D G3DSA:3.30.450.40 8 176 9.3E-25 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 Pfam PF03861 ANTAR domain 177 229 3.7E-21 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 SMART SM01012 174 229 1.3E-23 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 PIRSF PIRSF036625 1 234 1.6E-53 T 12-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 Gene3D G3DSA:1.10.10.10 177 233 3.6E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14490 68ef4e214a0a4a7d25c1459108bf6774 235 Pfam PF13185 GAF domain 24 162 9.6E-13 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_19350 72a75947c302b7323c18744ffef13db3 920 SUPERFAMILY SSF48208 403 818 6.24E-53 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_19350 72a75947c302b7323c18744ffef13db3 920 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 135 293 1.8E-44 T 12-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal AFR_19350 72a75947c302b7323c18744ffef13db3 920 Gene3D G3DSA:2.60.40.10 2 101 1.8E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_19350 72a75947c302b7323c18744ffef13db3 920 Gene3D G3DSA:1.50.10.10 102 845 1.1E-272 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_19350 72a75947c302b7323c18744ffef13db3 920 PIRSF PIRSF010631 1 852 2.9E-225 T 12-10-2018 IPR016007 Alpha-L-rhamnosidase AFR_19350 72a75947c302b7323c18744ffef13db3 920 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 755 831 2.4E-22 T 12-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain AFR_19350 72a75947c302b7323c18744ffef13db3 920 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 306 400 2.9E-21 T 12-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain AFR_19350 72a75947c302b7323c18744ffef13db3 920 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 406 753 8.4E-124 T 12-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain AFR_06170 9c4ca20340452922a1807d9e05ae7614 249 Pfam PF01061 ABC-2 type transporter 7 211 2.6E-24 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_06170 9c4ca20340452922a1807d9e05ae7614 249 PIRSF PIRSF006648 1 248 7.1E-63 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_22040 32ea2d6c5c68011724ba9fe8d0d9c42a 202 Pfam PF05401 Nodulation protein S (NodS) 14 141 1.4E-17 T 12-10-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 AFR_22040 32ea2d6c5c68011724ba9fe8d0d9c42a 202 SUPERFAMILY SSF53335 6 155 3.63E-22 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_22040 32ea2d6c5c68011724ba9fe8d0d9c42a 202 Gene3D G3DSA:3.40.50.150 24 187 1.6E-41 T 12-10-2018 AFR_26910 328adfc99692a8018f561f8fed50d083 213 Gene3D G3DSA:1.10.357.10 9 209 2.2E-25 T 12-10-2018 AFR_26910 328adfc99692a8018f561f8fed50d083 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 2.9E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_26910 328adfc99692a8018f561f8fed50d083 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 6.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_26910 328adfc99692a8018f561f8fed50d083 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 6.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_26910 328adfc99692a8018f561f8fed50d083 213 SUPERFAMILY SSF46689 11 73 1.05E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_26910 328adfc99692a8018f561f8fed50d083 213 SUPERFAMILY SSF48498 99 209 6.3E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 Gene3D G3DSA:2.60.40.10 657 770 1.1E-32 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 SMART SM01217 687 756 1.3E-26 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 PRINTS PR00133 Glycosyl hydrolase family 3 signature 183 199 1.5E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 PRINTS PR00133 Glycosyl hydrolase family 3 signature 114 130 1.5E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 PRINTS PR00133 Glycosyl hydrolase family 3 signature 214 230 1.5E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 PRINTS PR00133 Glycosyl hydrolase family 3 signature 285 303 1.5E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 PRINTS PR00133 Glycosyl hydrolase family 3 signature 137 156 1.5E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 SUPERFAMILY SSF52279 408 653 4.05E-40 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 408 650 1.9E-39 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 SUPERFAMILY SSF51445 4 407 4.21E-99 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 Pfam PF14310 Fibronectin type III-like domain 687 755 1.1E-19 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 25 365 2.1E-77 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 Gene3D G3DSA:3.20.20.300 14 384 2.4E-104 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 Gene3D G3DSA:3.40.50.1700 393 652 3.6E-54 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_17980 dbf8c68a2884bc964b8545d5c29e76e5 791 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 285 302 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AFR_26985 61cc2d097884271b90a281974da93afa 347 SUPERFAMILY SSF52242 98 214 9.58E-20 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_26985 61cc2d097884271b90a281974da93afa 347 Pfam PF02607 B12 binding domain 19 89 2.6E-12 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_26985 61cc2d097884271b90a281974da93afa 347 Gene3D G3DSA:3.40.50.280 97 216 4.5E-25 T 12-10-2018 AFR_26985 61cc2d097884271b90a281974da93afa 347 Pfam PF02310 B12 binding domain 102 207 3.2E-16 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_26985 61cc2d097884271b90a281974da93afa 347 Gene3D G3DSA:1.10.1240.10 16 92 5.0E-10 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 SUPERFAMILY SSF55729 293 381 2.61E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 Gene3D G3DSA:3.40.50.10330 20 277 3.8E-63 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 SUPERFAMILY SSF111331 17 277 3.4E-59 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 Hamap MF_00361 NAD kinase [nadK]. 3 278 25.168 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 Pfam PF14542 GCN5-related N-acetyl-transferase 302 379 1.3E-21 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 Gene3D G3DSA:3.40.630.30 297 382 5.7E-22 T 12-10-2018 AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 Pfam PF01513 ATP-NAD kinase 53 262 1.7E-42 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_33235 5fc7a2042569db33bda886bcfb02b917 387 Gene3D G3DSA:2.60.200.30 123 255 3.8E-63 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_01570 4d183cf8ad6259622c85f0218faabd84 416 Gene3D G3DSA:1.20.1250.20 204 395 2.4E-23 T 12-10-2018 AFR_01570 4d183cf8ad6259622c85f0218faabd84 416 Gene3D G3DSA:1.20.1250.20 11 192 1.1E-19 T 12-10-2018 AFR_01570 4d183cf8ad6259622c85f0218faabd84 416 SUPERFAMILY SSF103473 8 393 8.76E-49 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_01570 4d183cf8ad6259622c85f0218faabd84 416 Pfam PF07690 Major Facilitator Superfamily 28 201 1.7E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_01570 4d183cf8ad6259622c85f0218faabd84 416 Pfam PF07690 Major Facilitator Superfamily 221 399 4.6E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_39030 70ead87f0448bb75f751424c6ee77085 277 SUPERFAMILY SSF81301 7 62 1.9E-9 T 12-10-2018 AFR_39030 70ead87f0448bb75f751424c6ee77085 277 Pfam PF01909 Nucleotidyltransferase domain 19 51 8.1E-8 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFR_39030 70ead87f0448bb75f751424c6ee77085 277 Gene3D G3DSA:3.30.460.10 1 68 2.5E-7 T 12-10-2018 AFR_12245 ef8563147ca70690302e2a7bc401f122 339 Gene3D G3DSA:3.20.20.100 1 327 6.0E-110 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_12245 ef8563147ca70690302e2a7bc401f122 339 Pfam PF00248 Aldo/keto reductase family 16 313 3.9E-68 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_12245 ef8563147ca70690302e2a7bc401f122 339 PRINTS PR00069 Aldo-keto reductase signature 136 153 6.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_12245 ef8563147ca70690302e2a7bc401f122 339 PRINTS PR00069 Aldo-keto reductase signature 105 123 6.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_12245 ef8563147ca70690302e2a7bc401f122 339 PRINTS PR00069 Aldo-keto reductase signature 41 65 6.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_12245 ef8563147ca70690302e2a7bc401f122 339 SUPERFAMILY SSF51430 1 313 2.1E-93 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_01285 00fa281d358790d4267a056326a163d2 256 SUPERFAMILY SSF53448 14 223 3.0E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_01285 00fa281d358790d4267a056326a163d2 256 Pfam PF00535 Glycosyl transferase family 2 16 142 6.1E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_01285 00fa281d358790d4267a056326a163d2 256 Gene3D G3DSA:3.90.550.10 6 251 4.7E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23975 3391ad8b1c08efacb9002eefc363afb4 297 Gene3D G3DSA:1.10.3720.10 14 284 9.6E-56 T 12-10-2018 IPR035906 MetI-like superfamily AFR_23975 3391ad8b1c08efacb9002eefc363afb4 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 2.2E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_23975 3391ad8b1c08efacb9002eefc363afb4 297 SUPERFAMILY SSF161098 18 297 1.12E-65 T 12-10-2018 IPR035906 MetI-like superfamily AFR_28765 ef9f75d4f4570e3c6b2ed755d6faccf0 365 Pfam PF01757 Acyltransferase family 19 340 6.5E-22 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_17960 915c9b3831e730c4c6528d4a44366da9 514 Pfam PF17103 Stealth protein CR4, conserved region 4 468 514 1.1E-11 T 12-10-2018 IPR031356 Stealth protein CR4, conserved region 4 AFR_17960 915c9b3831e730c4c6528d4a44366da9 514 Pfam PF17101 Stealth protein CR1, conserved region 1 205 231 8.0E-15 T 12-10-2018 IPR031358 Stealth protein CR1, conserved region 1 AFR_17960 915c9b3831e730c4c6528d4a44366da9 514 Pfam PF11380 Stealth protein CR2, conserved region 2 242 347 7.9E-46 T 12-10-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 AFR_17960 915c9b3831e730c4c6528d4a44366da9 514 Pfam PF17102 Stealth protein CR3, conserved region 3 393 440 1.9E-18 T 12-10-2018 IPR031357 Stealth protein CR3, conserved region 3 AFR_01390 5c970402cff6f463451da81614448b35 168 SUPERFAMILY SSF88946 7 67 3.37E-8 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_01390 5c970402cff6f463451da81614448b35 168 Gene3D G3DSA:1.10.1740.10 2 79 2.1E-5 T 12-10-2018 AFR_01390 5c970402cff6f463451da81614448b35 168 Gene3D G3DSA:1.10.10.10 96 158 1.1E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01390 5c970402cff6f463451da81614448b35 168 Pfam PF08281 Sigma-70, region 4 100 151 9.5E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_01390 5c970402cff6f463451da81614448b35 168 SUPERFAMILY SSF88659 98 155 5.89E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_01390 5c970402cff6f463451da81614448b35 168 Pfam PF04542 Sigma-70 region 2 12 70 1.2E-5 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_35555 46f047aa7596351efaf6e2fb727d675b 303 SUPERFAMILY SSF52540 8 149 2.14E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35555 46f047aa7596351efaf6e2fb727d675b 303 Gene3D G3DSA:1.10.20.140 114 182 9.0E-90 T 12-10-2018 AFR_35555 46f047aa7596351efaf6e2fb727d675b 303 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 7 296 27.108 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFR_35555 46f047aa7596351efaf6e2fb727d675b 303 Pfam PF01715 IPP transferase 40 280 2.8E-74 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFR_35555 46f047aa7596351efaf6e2fb727d675b 303 Gene3D G3DSA:3.40.50.300 11 284 9.0E-90 T 12-10-2018 AFR_35555 46f047aa7596351efaf6e2fb727d675b 303 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 285 4.2E-75 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1242 1282 6.6E-4 T 12-10-2018 IPR006530 YD repeat AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1639 1677 0.0021 T 12-10-2018 IPR006530 YD repeat AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 SMART SM00306 1996 2091 8.7E-9 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 Pfam PF07591 Pretoxin HINT domain 2012 2135 6.0E-18 T 12-10-2018 AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 SUPERFAMILY SSF51294 1998 2135 6.02E-18 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1742 1818 1.5E-15 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 Gene3D G3DSA:2.170.16.10 1995 2134 8.9E-33 T 12-10-2018 AFR_39165 63cbdb53d008a9419e47588ca692cc74 2240 Gene3D G3DSA:2.180.10.10 1409 1818 5.8E-38 T 12-10-2018 AFR_40385 5ed923d1dbe800d0590aaadca9b2b8d4 304 Pfam PF00700 Bacterial flagellin C-terminal helical region 223 303 1.8E-5 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFR_40385 5ed923d1dbe800d0590aaadca9b2b8d4 304 Gene3D G3DSA:1.20.1330.10 43 250 1.5E-34 T 12-10-2018 AFR_40385 5ed923d1dbe800d0590aaadca9b2b8d4 304 Pfam PF00669 Bacterial flagellin N-terminal helical region 10 134 4.4E-15 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFR_40385 5ed923d1dbe800d0590aaadca9b2b8d4 304 SUPERFAMILY SSF64518 5 304 6.93E-56 T 12-10-2018 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 PRINTS PR00127 Clp protease catalytic subunit P signature 34 49 2.5E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 PRINTS PR00127 Clp protease catalytic subunit P signature 184 203 2.5E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 PRINTS PR00127 Clp protease catalytic subunit P signature 105 122 2.5E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 PRINTS PR00127 Clp protease catalytic subunit P signature 74 94 2.5E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 PRINTS PR00127 Clp protease catalytic subunit P signature 126 145 2.5E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 Gene3D G3DSA:3.90.226.10 11 216 8.5E-76 T 12-10-2018 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 SUPERFAMILY SSF52096 26 209 3.98E-62 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 Pfam PF00574 Clp protease 33 208 9.4E-76 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 18 209 39.929 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07545 33ba6c1c1af4a869c4d79e6ced260cfb 218 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 105 116 - T 12-10-2018 IPR018215 ClpP, Ser active site AFR_27230 a71f84a852c6a9908b0b9a72dba40c0f 585 Gene3D G3DSA:1.10.510.10 100 278 7.8E-43 T 12-10-2018 AFR_27230 a71f84a852c6a9908b0b9a72dba40c0f 585 Pfam PF00069 Protein kinase domain 25 271 6.5E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_27230 a71f84a852c6a9908b0b9a72dba40c0f 585 Gene3D G3DSA:3.30.200.20 12 99 3.0E-17 T 12-10-2018 AFR_27230 a71f84a852c6a9908b0b9a72dba40c0f 585 SUPERFAMILY SSF56112 15 296 2.13E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_27230 a71f84a852c6a9908b0b9a72dba40c0f 585 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 27 49 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_27230 a71f84a852c6a9908b0b9a72dba40c0f 585 SMART SM00220 21 273 3.7E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_27230 a71f84a852c6a9908b0b9a72dba40c0f 585 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_19405 7acb5901547fdc8bab853e18c536370a 321 Gene3D G3DSA:3.90.180.10 8 318 9.3E-89 T 12-10-2018 AFR_19405 7acb5901547fdc8bab853e18c536370a 321 SUPERFAMILY SSF50129 1 153 2.74E-34 T 12-10-2018 IPR011032 GroES-like superfamily AFR_19405 7acb5901547fdc8bab853e18c536370a 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 94 1.4E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_19405 7acb5901547fdc8bab853e18c536370a 321 Gene3D G3DSA:3.40.50.720 130 270 9.3E-89 T 12-10-2018 AFR_19405 7acb5901547fdc8bab853e18c536370a 321 SMART SM00829 10 319 3.8E-14 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_19405 7acb5901547fdc8bab853e18c536370a 321 Pfam PF13602 Zinc-binding dehydrogenase 188 319 9.6E-23 T 12-10-2018 AFR_19405 7acb5901547fdc8bab853e18c536370a 321 SUPERFAMILY SSF51735 119 294 2.93E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40135 365a7ff0bdbb6995aff838565658c03d 338 Gene3D G3DSA:1.10.287.70 12 116 1.9E-15 T 12-10-2018 AFR_40135 365a7ff0bdbb6995aff838565658c03d 338 Pfam PF02254 TrkA-N domain 124 242 1.1E-27 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFR_40135 365a7ff0bdbb6995aff838565658c03d 338 SUPERFAMILY SSF81324 13 145 9.94E-23 T 12-10-2018 AFR_40135 365a7ff0bdbb6995aff838565658c03d 338 SUPERFAMILY SSF51735 119 265 4.32E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40135 365a7ff0bdbb6995aff838565658c03d 338 Gene3D G3DSA:3.40.50.720 117 258 1.0E-38 T 12-10-2018 AFR_40135 365a7ff0bdbb6995aff838565658c03d 338 Pfam PF07885 Ion channel 23 104 1.7E-13 T 12-10-2018 IPR013099 Potassium channel domain AFR_35765 2e04cd6f614a9abfcb3a3c610d754a3c 245 Gene3D G3DSA:3.40.630.30 38 205 2.1E-26 T 12-10-2018 AFR_35765 2e04cd6f614a9abfcb3a3c610d754a3c 245 SUPERFAMILY SSF55729 3 148 3.36E-5 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 SMART SM00354 2 69 2.3E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 SUPERFAMILY SSF53822 59 335 9.23E-62 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 Pfam PF13377 Periplasmic binding protein-like domain 173 329 1.4E-35 T 12-10-2018 AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 SUPERFAMILY SSF47413 5 48 8.85E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 2.4E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 Gene3D G3DSA:1.10.260.40 2 56 1.6E-15 T 12-10-2018 AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 Gene3D G3DSA:3.40.50.2300 163 326 6.4E-67 T 12-10-2018 AFR_33120 e46b5a93fd869682fcaef37bb2ca860b 340 Gene3D G3DSA:3.40.50.2300 60 321 6.4E-67 T 12-10-2018 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 SUPERFAMILY SSF47413 1 31 4.22E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 30 1.5E-7 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 Gene3D G3DSA:3.40.50.2300 54 295 1.8E-60 T 12-10-2018 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 SMART SM00354 1 70 0.0038 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 Gene3D G3DSA:3.40.50.2300 147 276 1.8E-60 T 12-10-2018 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 Gene3D G3DSA:1.10.260.40 1 36 1.7E-8 T 12-10-2018 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 Pfam PF13377 Periplasmic binding protein-like domain 156 316 1.6E-38 T 12-10-2018 AFR_24510 0f9ef86b1846f384e7022cf29dea3bc2 322 SUPERFAMILY SSF53822 54 319 4.91E-60 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 102 130 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 115 134 2.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 103 2.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 40 51 2.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 Gene3D G3DSA:3.40.50.720 2 204 3.1E-62 T 12-10-2018 AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 187 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 105 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 152 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 40 51 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 134 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 SUPERFAMILY SSF51735 6 203 3.66E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24655 87d2801ff2ba6b8c8c07d4eb8acfa3b2 204 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 202 2.6E-49 T 12-10-2018 AFR_04410 aec54b2b296281058502f134a0fec826 148 Gene3D G3DSA:3.10.129.10 2 148 1.2E-47 T 12-10-2018 AFR_04410 aec54b2b296281058502f134a0fec826 148 PIRSF PIRSF018072 1 148 5.3E-58 T 12-10-2018 IPR016709 Uncharacterised protein family UPF0336 AFR_04410 aec54b2b296281058502f134a0fec826 148 Pfam PF13452 N-terminal half of MaoC dehydratase 9 137 6.9E-37 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 AFR_04410 aec54b2b296281058502f134a0fec826 148 SUPERFAMILY SSF54637 9 147 1.32E-39 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_04410 aec54b2b296281058502f134a0fec826 148 Hamap MF_00799 UPF0336 protein . 1 148 33.324 T 12-10-2018 IPR016709 Uncharacterised protein family UPF0336 AFR_37260 92ac1dec75bcb1a6bfa8e3c41c2ac236 219 Pfam PF01939 Endonuclease NucS 1 219 3.9E-81 T 12-10-2018 IPR002793 Endonuclease NucS GO:0004519 AFR_37260 92ac1dec75bcb1a6bfa8e3c41c2ac236 219 Gene3D G3DSA:2.70.180.20 1 90 1.7E-20 T 12-10-2018 AFR_37260 92ac1dec75bcb1a6bfa8e3c41c2ac236 219 Gene3D G3DSA:3.40.1350.10 94 205 3.6E-24 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFR_37260 92ac1dec75bcb1a6bfa8e3c41c2ac236 219 Hamap MF_00722 Endonuclease NucS [nucS]. 1 211 31.251 T 12-10-2018 IPR002793 Endonuclease NucS GO:0004519 AFR_33055 6320dbc7f388aad20fc7e769dafa1adf 482 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 311 472 2.1E-30 T 12-10-2018 IPR000160 GGDEF domain AFR_33055 6320dbc7f388aad20fc7e769dafa1adf 482 SUPERFAMILY SSF55073 320 473 1.26E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_33055 6320dbc7f388aad20fc7e769dafa1adf 482 SMART SM00267 304 473 1.0E-55 T 12-10-2018 IPR000160 GGDEF domain AFR_33055 6320dbc7f388aad20fc7e769dafa1adf 482 Gene3D G3DSA:3.30.70.270 313 477 6.9E-48 T 12-10-2018 AFR_33055 6320dbc7f388aad20fc7e769dafa1adf 482 Pfam PF00990 Diguanylate cyclase, GGDEF domain 315 468 3.4E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 Gene3D G3DSA:3.40.1160.10 1 249 4.0E-91 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 PIRSF PIRSF000726 1 62 1.6E-20 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 PIRSF PIRSF000726 59 414 1.4E-131 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 SUPERFAMILY SSF53633 4 244 7.59E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 407 2.1E-126 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 Pfam PF00696 Amino acid kinase family 3 231 1.8E-56 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 Pfam PF01842 ACT domain 268 329 6.6E-10 T 12-10-2018 IPR002912 ACT domain AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 2 406 7.0E-136 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 SUPERFAMILY SSF55021 332 413 5.44E-23 T 12-10-2018 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 SUPERFAMILY SSF55021 251 331 2.51E-19 T 12-10-2018 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 Gene3D G3DSA:3.30.2130.10 250 421 2.0E-66 T 12-10-2018 AFR_41745 afe97e2d19bdf04f45414f0ab1ffc654 421 Pfam PF13840 ACT domain 341 403 1.6E-11 T 12-10-2018 IPR027795 CASTOR, ACT domain AFR_01855 da00e98e5de1208e563f5dd717c7aab0 215 Pfam PF00482 Type II secretion system (T2SS), protein F 82 201 2.2E-20 T 12-10-2018 IPR018076 Type II secretion system F domain AFR_01855 da00e98e5de1208e563f5dd717c7aab0 215 Gene3D G3DSA:1.20.81.30 75 179 8.9E-7 T 12-10-2018 AFR_32585 42f7d08c51c218ababf75612883379ed 419 Gene3D G3DSA:1.20.1250.20 27 408 2.6E-25 T 12-10-2018 AFR_32585 42f7d08c51c218ababf75612883379ed 419 SUPERFAMILY SSF103473 10 409 1.83E-32 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_32585 42f7d08c51c218ababf75612883379ed 419 Pfam PF05977 Transmembrane secretion effector 22 333 4.8E-22 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 Gene3D G3DSA:3.40.50.12740 2 218 2.4E-65 T 12-10-2018 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 SMART SM00421 155 212 1.2E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.3E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 5.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 5.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 5.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 Pfam PF00072 Response regulator receiver domain 4 117 5.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 SUPERFAMILY SSF52172 1 133 4.27E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 SUPERFAMILY SSF46894 148 218 2.65E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_12440 afc0a4a13679b62dc0a6928fa0d8ae40 233 SMART SM00448 2 116 1.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 Gene3D G3DSA:3.30.70.270 445 617 7.3E-42 T 12-10-2018 AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 SUPERFAMILY SSF55785 307 435 2.84E-14 T 12-10-2018 IPR035965 PAS domain superfamily AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 Pfam PF00563 EAL domain 621 855 3.2E-63 T 12-10-2018 IPR001633 EAL domain AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 SMART SM00267 439 605 4.7E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 Gene3D G3DSA:3.20.20.450 618 870 5.5E-83 T 12-10-2018 IPR035919 EAL domain superfamily AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 Gene3D G3DSA:3.30.450.20 310 444 1.4E-14 T 12-10-2018 AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 SMART SM00052 615 860 2.8E-84 T 12-10-2018 IPR001633 EAL domain AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 446 604 3.8E-26 T 12-10-2018 IPR000160 GGDEF domain AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 SUPERFAMILY SSF55073 455 607 1.96E-34 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 SUPERFAMILY SSF141868 620 867 2.22E-73 T 12-10-2018 IPR035919 EAL domain superfamily AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 Pfam PF00990 Diguanylate cyclase, GGDEF domain 451 601 2.1E-29 T 12-10-2018 IPR000160 GGDEF domain AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 SMART SM00091 322 388 3.0E-9 T 12-10-2018 IPR000014 PAS domain AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 446 5.9E-11 T 12-10-2018 IPR000014 PAS domain AFR_36935 9278e76391ca38447ec149a8a895d3f0 870 Pfam PF00989 PAS fold 323 390 3.5E-8 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_42760 28e117912811d830a45455712b7b6cef 410 Pfam PF14433 SUKH-3 immunity protein 252 397 1.1E-32 T 12-10-2018 IPR025850 SUKH-3 immunity protein AFR_42760 28e117912811d830a45455712b7b6cef 410 Pfam PF14431 YwqJ-like deaminase 103 226 2.0E-15 T 12-10-2018 IPR025968 YwqJ-like deaminase AFR_22035 1e8210d3a0947fbb9d14adc5189006ff 224 Pfam PF00535 Glycosyl transferase family 2 7 142 4.1E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_22035 1e8210d3a0947fbb9d14adc5189006ff 224 Gene3D G3DSA:3.90.550.10 1 206 2.9E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_22035 1e8210d3a0947fbb9d14adc5189006ff 224 SUPERFAMILY SSF53448 5 205 4.45E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_12840 5f8baf7a5790152e34444ef71210a731 848 SUPERFAMILY SSF50370 704 844 1.31E-38 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_12840 5f8baf7a5790152e34444ef71210a731 848 Pfam PF00754 F5/8 type C domain 586 697 2.3E-10 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_12840 5f8baf7a5790152e34444ef71210a731 848 Gene3D G3DSA:2.60.120.260 553 706 4.2E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_12840 5f8baf7a5790152e34444ef71210a731 848 SMART SM00458 706 843 1.9E-8 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_12840 5f8baf7a5790152e34444ef71210a731 848 Gene3D G3DSA:2.80.10.50 707 842 3.1E-37 T 12-10-2018 AFR_12840 5f8baf7a5790152e34444ef71210a731 848 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 796 844 2.9E-10 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_12840 5f8baf7a5790152e34444ef71210a731 848 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 705 783 1.2E-16 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_12840 5f8baf7a5790152e34444ef71210a731 848 Gene3D G3DSA:1.50.10.10 134 459 1.7E-27 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_12840 5f8baf7a5790152e34444ef71210a731 848 SUPERFAMILY SSF48208 136 528 5.35E-37 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_12840 5f8baf7a5790152e34444ef71210a731 848 SUPERFAMILY SSF49785 598 704 1.98E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_39370 d276ec456447cd6aec258baf683a1094 251 Pfam PF01061 ABC-2 type transporter 9 214 2.1E-30 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_39370 d276ec456447cd6aec258baf683a1094 251 PIRSF PIRSF006648 1 251 4.4E-48 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_21590 c344ab4ab9a852cbbde1a49d0fba7a36 250 Pfam PF08241 Methyltransferase domain 42 131 3.9E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_21590 c344ab4ab9a852cbbde1a49d0fba7a36 250 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AFR_21590 c344ab4ab9a852cbbde1a49d0fba7a36 250 Gene3D G3DSA:3.40.50.150 8 205 1.4E-34 T 12-10-2018 AFR_21590 c344ab4ab9a852cbbde1a49d0fba7a36 250 SUPERFAMILY SSF53335 9 204 8.97E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_17430 5f383a1cefa2785a3fcce2bea8f491a4 153 Gene3D G3DSA:3.40.630.30 3 149 3.8E-28 T 12-10-2018 AFR_17430 5f383a1cefa2785a3fcce2bea8f491a4 153 Pfam PF00583 Acetyltransferase (GNAT) family 16 128 9.3E-15 T 12-10-2018 IPR000182 GNAT domain AFR_17430 5f383a1cefa2785a3fcce2bea8f491a4 153 SUPERFAMILY SSF55729 1 146 6.0E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40885 43481047d66ab5968fc82063432a98c5 540 Gene3D G3DSA:1.10.560.10 7 519 2.1E-221 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFR_40885 43481047d66ab5968fc82063432a98c5 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_40885 43481047d66ab5968fc82063432a98c5 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 4.1E-93 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AFR_40885 43481047d66ab5968fc82063432a98c5 540 Gene3D G3DSA:3.30.260.10 135 408 2.1E-221 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFR_40885 43481047d66ab5968fc82063432a98c5 540 Gene3D G3DSA:3.50.7.10 190 370 2.1E-221 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily AFR_40885 43481047d66ab5968fc82063432a98c5 540 SUPERFAMILY SSF48592 6 519 4.58E-73 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFR_40885 43481047d66ab5968fc82063432a98c5 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.112 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_40885 43481047d66ab5968fc82063432a98c5 540 SUPERFAMILY SSF54849 137 203 1.05E-26 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFR_40885 43481047d66ab5968fc82063432a98c5 540 SUPERFAMILY SSF52029 184 374 2.39E-81 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily AFR_40885 43481047d66ab5968fc82063432a98c5 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 1.5E-247 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_40885 43481047d66ab5968fc82063432a98c5 540 PRINTS PR00298 60kDa chaperonin signature 266 289 3.7E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_40885 43481047d66ab5968fc82063432a98c5 540 PRINTS PR00298 60kDa chaperonin signature 26 52 3.7E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_40885 43481047d66ab5968fc82063432a98c5 540 PRINTS PR00298 60kDa chaperonin signature 82 109 3.7E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_40885 43481047d66ab5968fc82063432a98c5 540 PRINTS PR00298 60kDa chaperonin signature 348 373 3.7E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_40885 43481047d66ab5968fc82063432a98c5 540 PRINTS PR00298 60kDa chaperonin signature 396 417 3.7E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Gene3D G3DSA:1.10.10.10 446 523 1.9E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Gene3D G3DSA:1.10.601.10 219 263 6.9E-10 T 12-10-2018 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Gene3D G3DSA:1.10.601.10 264 362 2.8E-51 T 12-10-2018 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Pfam PF04542 Sigma-70 region 2 290 359 2.0E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 314 327 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 483 509 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 124 523 32.714 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Gene3D G3DSA:1.10.10.10 363 438 3.4E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 SUPERFAMILY SSF88659 363 436 2.43E-22 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 286 522 4.4E-114 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 SUPERFAMILY SSF88946 218 360 8.37E-55 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Pfam PF04545 Sigma-70, region 4 458 511 1.6E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Pfam PF04539 Sigma-70 region 3 369 444 1.9E-28 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 PRINTS PR00046 Major sigma-70 factor signature 483 498 4.5E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 PRINTS PR00046 Major sigma-70 factor signature 498 509 4.5E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 PRINTS PR00046 Major sigma-70 factor signature 314 327 4.5E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 PRINTS PR00046 Major sigma-70 factor signature 338 346 4.5E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 PRINTS PR00046 Major sigma-70 factor signature 462 474 4.5E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 SUPERFAMILY SSF88659 422 522 1.57E-26 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 Pfam PF00140 Sigma-70 factor, region 1.2 221 254 5.0E-17 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_35325 b7095e14b8c1869f76c204a483d6775f 523 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 286 511 1.7E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_19525 157ed0fe334f50252db573f21e752557 246 SUPERFAMILY SSF52540 3 227 1.14E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19525 157ed0fe334f50252db573f21e752557 246 SMART SM00382 28 220 2.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_19525 157ed0fe334f50252db573f21e752557 246 Gene3D G3DSA:3.40.50.300 1 238 1.1E-68 T 12-10-2018 AFR_19525 157ed0fe334f50252db573f21e752557 246 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 12 196 1.4E-66 T 12-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 AFR_19525 157ed0fe334f50252db573f21e752557 246 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_19525 157ed0fe334f50252db573f21e752557 246 Pfam PF00005 ABC transporter 19 167 3.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_00500 c598f4c093eb768b877c8d052a74739a 192 Pfam PF05685 Putative restriction endonuclease 10 145 2.5E-24 T 12-10-2018 IPR008538 Domain of unknown function DUF820 AFR_00500 c598f4c093eb768b877c8d052a74739a 192 SUPERFAMILY SSF52980 5 135 8.04E-22 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_00500 c598f4c093eb768b877c8d052a74739a 192 Gene3D G3DSA:3.90.1570.10 3 150 3.7E-21 T 12-10-2018 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 SUPERFAMILY SSF52016 662 921 8.04E-87 T 12-10-2018 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 Gene3D G3DSA:3.30.499.20 8 364 3.0E-156 T 12-10-2018 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 Gene3D G3DSA:3.20.19.10 685 922 5.5E-105 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 Pfam PF00330 Aconitase family (aconitate hydratase) 74 593 7.2E-177 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 Pfam PF00694 Aconitase C-terminal domain 723 849 2.1E-44 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 ProSitePatterns PS01244 Aconitase family signature 2. 524 537 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 Gene3D G3DSA:1.10.1440.20 622 683 1.3E-17 T 12-10-2018 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 SUPERFAMILY SSF53732 5 658 3.79E-218 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 ProSitePatterns PS00450 Aconitase family signature 1. 458 474 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 166 174 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 209 224 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 271 284 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 364 378 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 195 208 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 524 537 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 285 298 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 462 473 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 PRINTS PR00415 Aconitase family signature 142 155 2.4E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_10930 511e73dbca495cd473fecb051ac9373e 924 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 27 921 0.0 T 12-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 AFR_38580 415727fbdf979ccade770f927a206ed4 286 SUPERFAMILY SSF88659 109 165 3.49E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_38580 415727fbdf979ccade770f927a206ed4 286 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 5 281 3.3E-91 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria AFR_38580 415727fbdf979ccade770f927a206ed4 286 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 165 2.4E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_38580 415727fbdf979ccade770f927a206ed4 286 Gene3D G3DSA:1.10.10.10 107 167 2.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38580 415727fbdf979ccade770f927a206ed4 286 SUPERFAMILY SSF54427 180 280 4.7E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_38580 415727fbdf979ccade770f927a206ed4 286 Pfam PF04542 Sigma-70 region 2 5 69 3.3E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_38580 415727fbdf979ccade770f927a206ed4 286 Pfam PF08281 Sigma-70, region 4 111 163 1.1E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_38580 415727fbdf979ccade770f927a206ed4 286 Gene3D G3DSA:3.10.450.50 174 285 2.7E-13 T 12-10-2018 AFR_38580 415727fbdf979ccade770f927a206ed4 286 SUPERFAMILY SSF88946 5 72 3.69E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_38580 415727fbdf979ccade770f927a206ed4 286 Gene3D G3DSA:1.10.1740.10 1 71 4.9E-17 T 12-10-2018 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 SUPERFAMILY SSF53822 62 337 1.28E-71 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 Gene3D G3DSA:3.40.50.2300 166 333 6.9E-78 T 12-10-2018 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 SMART SM00354 5 72 6.0E-21 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 SUPERFAMILY SSF47413 5 51 3.75E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 Pfam PF13377 Periplasmic binding protein-like domain 174 336 2.6E-38 T 12-10-2018 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 50 1.0E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 Gene3D G3DSA:1.10.260.40 4 60 7.5E-16 T 12-10-2018 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 Gene3D G3DSA:3.40.50.2300 63 328 6.9E-78 T 12-10-2018 AFR_19385 dae5d0a515d9becfb00fc4ae3638cb0b 353 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 12-10-2018 AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 79 2.4E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 Pfam PF00155 Aminotransferase class I and II 141 414 8.1E-24 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 Gene3D G3DSA:1.10.10.10 17 99 4.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 SUPERFAMILY SSF53383 114 465 9.43E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 4.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 4.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 SUPERFAMILY SSF46785 13 91 7.86E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 Gene3D G3DSA:3.40.640.10 110 458 1.3E-111 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_10230 7306ed0fd2405bc5064f6578d81e7be0 467 SMART SM00345 20 79 1.2E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_22645 78177e3c174276c4ab30b20e0308b248 383 Gene3D G3DSA:3.20.20.150 41 289 6.1E-19 T 12-10-2018 AFR_22645 78177e3c174276c4ab30b20e0308b248 383 SUPERFAMILY SSF51658 41 245 3.67E-27 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_22645 78177e3c174276c4ab30b20e0308b248 383 Pfam PF01261 Xylose isomerase-like TIM barrel 43 240 3.0E-13 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_42145 7df1f0b8986ac9e1856ef006d270ff47 338 Pfam PF12679 ABC-2 family transporter protein 75 224 2.1E-8 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Pfam PF11852 Domain of unknown function (DUF3372) 1647 1800 7.9E-49 T 12-10-2018 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Pfam PF00128 Alpha amylase, catalytic domain 93 461 1.8E-77 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:2.60.40.1180 516 605 1.2E-11 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF51011 1708 1800 1.27E-20 T 12-10-2018 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:2.60.40.10 1059 1165 1.4E-27 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF81296 1065 1168 8.8E-20 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:3.20.20.80 1166 1737 2.2E-211 T 12-10-2018 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:2.60.40.1180 1738 1801 2.9E-18 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 1066 1151 9.7E-13 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:2.60.40.1110 712 813 1.8E-27 T 12-10-2018 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF49452 714 818 3.92E-30 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SMART SM00642 55 513 1.3E-90 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:3.20.20.80 44 482 6.7E-104 T 12-10-2018 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:2.60.40.1110 814 916 1.9E-27 T 12-10-2018 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF51445 50 522 3.07E-85 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF51445 1165 1704 1.14E-111 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:2.60.40.1130 930 1058 1.3E-25 T 12-10-2018 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF81296 927 1058 5.74E-25 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Gene3D G3DSA:2.60.40.10 614 709 2.4E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF51011 527 603 1.64E-6 T 12-10-2018 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 SUPERFAMILY SSF49452 816 915 3.92E-31 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Pfam PF03714 Bacterial pullanase-associated domain 824 914 1.2E-18 T 12-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 Pfam PF03714 Bacterial pullanase-associated domain 717 811 5.8E-22 T 12-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 AFR_27730 5f8644226073a1ea38dac183a5800b44 1801 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 930 1800 9.6E-302 T 12-10-2018 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 AFR_39195 1877b95cfdc51e7936d27f58f767d816 353 Gene3D G3DSA:3.40.50.11270 40 124 1.5E-105 T 12-10-2018 AFR_39195 1877b95cfdc51e7936d27f58f767d816 353 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 31 309 3.4E-97 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFR_39195 1877b95cfdc51e7936d27f58f767d816 353 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 29 312 35.963 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFR_39195 1877b95cfdc51e7936d27f58f767d816 353 Gene3D G3DSA:3.40.1010.20 34 307 1.5E-105 T 12-10-2018 AFR_39195 1877b95cfdc51e7936d27f58f767d816 353 Gene3D G3DSA:3.40.1010.20 125 221 1.5E-105 T 12-10-2018 AFR_39195 1877b95cfdc51e7936d27f58f767d816 353 Pfam PF02401 LytB protein 31 308 9.5E-87 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 187 333 9.8E-50 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 Gene3D G3DSA:3.10.170.10 186 337 4.0E-51 T 12-10-2018 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 324 340 3.2E-24 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 290 310 3.2E-24 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 412 428 3.2E-24 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 345 356 3.2E-24 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 Gene3D G3DSA:1.10.390.10 338 507 3.4E-53 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 49 93 1.5E-14 T 12-10-2018 IPR011096 FTP domain AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 SUPERFAMILY SSF55486 185 507 7.51E-84 T 12-10-2018 AFR_37175 9c1f70e0b4bc8f911ddde203f5e77775 514 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 336 507 3.9E-52 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 AFR_00260 f8d5f3ea66caae7cd25c90ee2df1f87a 357 Gene3D G3DSA:3.40.50.720 5 278 1.8E-58 T 12-10-2018 AFR_00260 f8d5f3ea66caae7cd25c90ee2df1f87a 357 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 278 7.9E-33 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_00260 f8d5f3ea66caae7cd25c90ee2df1f87a 357 SUPERFAMILY SSF51735 3 347 3.04E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_00260 f8d5f3ea66caae7cd25c90ee2df1f87a 357 Gene3D G3DSA:3.90.25.10 214 346 1.8E-58 T 12-10-2018 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1 503 3.7E-167 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 Pfam PF01808 AICARFT/IMPCHase bienzyme 125 436 2.3E-111 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 SUPERFAMILY SSF53927 199 503 1.3E-117 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 Gene3D G3DSA:3.40.50.1380 1 188 1.3E-74 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 Gene3D G3DSA:3.40.140.20 373 503 1.9E-50 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 Gene3D G3DSA:3.40.140.20 195 346 7.5E-60 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 SMART SM00798 125 437 1.9E-176 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 SMART SM00851 6 120 4.6E-47 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 PIRSF PIRSF000414 1 503 3.5E-190 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 SUPERFAMILY SSF52335 1 182 9.61E-56 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 Pfam PF02142 MGS-like domain 6 119 1.6E-23 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFR_05115 87f5a556a2229f662d715ad2cd4c3e1d 503 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 503 39.846 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_41105 09c785aa00cb6849f6e8f3087fd15dc1 303 SUPERFAMILY SSF52980 186 291 2.04E-9 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_41105 09c785aa00cb6849f6e8f3087fd15dc1 303 Gene3D G3DSA:3.40.960.10 192 293 4.0E-11 T 12-10-2018 AFR_41105 09c785aa00cb6849f6e8f3087fd15dc1 303 Pfam PF04480 Protein of unknown function (DUF559) 233 290 3.2E-6 T 12-10-2018 IPR007569 Protein of unknown function DUF559 AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 468 8.6E-44 T 12-10-2018 IPR000160 GGDEF domain AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 Gene3D G3DSA:3.30.70.270 308 476 3.2E-55 T 12-10-2018 AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 SUPERFAMILY SSF55073 314 470 5.1E-47 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 SMART SM00091 183 249 2.3E-10 T 12-10-2018 IPR000014 PAS domain AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 Pfam PF08447 PAS fold 206 277 1.9E-11 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 Gene3D G3DSA:3.30.450.20 179 307 3.3E-23 T 12-10-2018 AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 180 303 1.0E-20 T 12-10-2018 IPR000014 PAS domain AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 SMART SM00267 298 470 1.4E-66 T 12-10-2018 IPR000160 GGDEF domain AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 Pfam PF00990 Diguanylate cyclase, GGDEF domain 309 465 1.2E-47 T 12-10-2018 IPR000160 GGDEF domain AFR_20180 dd3c3bb86daf3c3746b62018ec173e0f 480 SUPERFAMILY SSF55785 170 296 8.83E-22 T 12-10-2018 IPR035965 PAS domain superfamily AFR_22280 a5d2a3165031d5378f12699a98424c62 441 Pfam PF01565 FAD binding domain 39 177 1.7E-44 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_22280 a5d2a3165031d5378f12699a98424c62 441 SUPERFAMILY SSF56176 24 215 7.94E-66 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_22280 a5d2a3165031d5378f12699a98424c62 441 Gene3D G3DSA:1.10.45.10 401 441 1.7E-13 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFR_22280 a5d2a3165031d5378f12699a98424c62 441 Gene3D G3DSA:3.30.465.40 17 232 4.0E-72 T 12-10-2018 AFR_22280 a5d2a3165031d5378f12699a98424c62 441 SUPERFAMILY SSF55103 188 440 1.96E-49 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFR_22280 a5d2a3165031d5378f12699a98424c62 441 Gene3D G3DSA:3.30.70.2740 323 400 3.5E-11 T 12-10-2018 AFR_22280 a5d2a3165031d5378f12699a98424c62 441 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 439 2.7E-51 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFR_25880 41609d88150d3edfcdddfd56ebe25972 337 Gene3D G3DSA:3.40.50.720 144 283 1.4E-74 T 12-10-2018 AFR_25880 41609d88150d3edfcdddfd56ebe25972 337 Gene3D G3DSA:3.90.180.10 19 321 1.4E-74 T 12-10-2018 AFR_25880 41609d88150d3edfcdddfd56ebe25972 337 Pfam PF00107 Zinc-binding dehydrogenase 173 297 9.9E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_25880 41609d88150d3edfcdddfd56ebe25972 337 SMART SM00829 11 333 3.3E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_25880 41609d88150d3edfcdddfd56ebe25972 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 129 1.2E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_25880 41609d88150d3edfcdddfd56ebe25972 337 SUPERFAMILY SSF51735 135 306 2.79E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_25880 41609d88150d3edfcdddfd56ebe25972 337 SUPERFAMILY SSF50129 9 157 6.09E-33 T 12-10-2018 IPR011032 GroES-like superfamily AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 Pfam PF00108 Thiolase, N-terminal domain 6 273 1.5E-71 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 Gene3D G3DSA:3.40.47.10 140 401 1.2E-149 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 Gene3D G3DSA:3.40.47.10 7 287 1.2E-149 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 3.2E-138 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 SUPERFAMILY SSF53901 3 281 9.77E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 PIRSF PIRSF000429 1 404 1.7E-131 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 SUPERFAMILY SSF53901 282 403 3.3E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_20795 5d1c1cdedb5e80bd30f5690502cacb4c 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 7.9E-47 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFR_24100 ee786644df052d11a487fa18069988fe 251 SMART SM01134 71 232 5.6E-54 T 12-10-2018 AFR_24100 ee786644df052d11a487fa18069988fe 251 SMART SM00420 6 58 1.3E-6 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_24100 ee786644df052d11a487fa18069988fe 251 SUPERFAMILY SSF100950 74 231 1.36E-25 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_24100 ee786644df052d11a487fa18069988fe 251 Pfam PF00455 DeoR C terminal sensor domain 74 230 1.8E-41 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain AFR_24100 ee786644df052d11a487fa18069988fe 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 2.6E-11 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_24100 ee786644df052d11a487fa18069988fe 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 8.4E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_24100 ee786644df052d11a487fa18069988fe 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 8.4E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_24100 ee786644df052d11a487fa18069988fe 251 SUPERFAMILY SSF46785 1 55 6.52E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24100 ee786644df052d11a487fa18069988fe 251 Gene3D G3DSA:1.10.10.10 2 56 2.1E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02570 9a1875452888c63a0b7b8fade60cd3e5 99 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 4 88 3.4E-16 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_02570 9a1875452888c63a0b7b8fade60cd3e5 99 SUPERFAMILY SSF82607 5 93 9.55E-19 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_02570 9a1875452888c63a0b7b8fade60cd3e5 99 Gene3D G3DSA:3.30.1310.10 1 99 9.3E-20 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_02570 9a1875452888c63a0b7b8fade60cd3e5 99 PIRSF PIRSF004555 2 98 6.9E-19 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_02570 9a1875452888c63a0b7b8fade60cd3e5 99 Pfam PF02575 YbaB/EbfC DNA-binding family 11 94 1.6E-20 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 Gene3D G3DSA:1.10.8.60 183 257 2.6E-30 T 12-10-2018 AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 Gene3D G3DSA:1.10.10.10 258 336 8.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 271 327 6.0E-19 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 2.8E-30 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 SUPERFAMILY SSF46785 257 331 2.29E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 3.5E-132 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 SUPERFAMILY SSF52540 21 251 1.01E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 6 236 3.3E-105 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 SMART SM00382 52 183 7.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 Gene3D G3DSA:3.40.50.300 21 182 2.7E-35 T 12-10-2018 AFR_31060 7aa8508a083d5e8a659a344b9157a798 352 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 352 157.945 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFR_22555 97282290fbeafe99afa88f697bc33645 258 Pfam PF08220 DeoR-like helix-turn-helix domain 11 64 1.1E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_22555 97282290fbeafe99afa88f697bc33645 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFR_22555 97282290fbeafe99afa88f697bc33645 258 SMART SM00420 11 63 2.0E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_22555 97282290fbeafe99afa88f697bc33645 258 SUPERFAMILY SSF46785 10 71 1.23E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_22555 97282290fbeafe99afa88f697bc33645 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 1.1E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_22555 97282290fbeafe99afa88f697bc33645 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 1.1E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_22555 97282290fbeafe99afa88f697bc33645 258 SMART SM01134 77 239 1.9E-53 T 12-10-2018 AFR_22555 97282290fbeafe99afa88f697bc33645 258 Pfam PF00455 DeoR C terminal sensor domain 79 238 2.9E-46 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain AFR_22555 97282290fbeafe99afa88f697bc33645 258 SUPERFAMILY SSF100950 79 239 4.19E-26 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_22555 97282290fbeafe99afa88f697bc33645 258 Gene3D G3DSA:1.10.10.10 8 96 1.2E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36590 2ce122b614ba737039120c2ffc41c97a 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 2.4E-22 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36590 2ce122b614ba737039120c2ffc41c97a 63 SUPERFAMILY SSF143800 2 62 3.53E-24 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36590 2ce122b614ba737039120c2ffc41c97a 63 Gene3D G3DSA:2.30.170.40 3 62 7.4E-20 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36590 2ce122b614ba737039120c2ffc41c97a 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 18.349 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36590 2ce122b614ba737039120c2ffc41c97a 63 Pfam PF00830 Ribosomal L28 family 4 59 3.6E-23 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_23655 935e1694cbfc5aac7079e78a7572bc94 294 Pfam PF00296 Luciferase-like monooxygenase 15 201 1.1E-35 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_23655 935e1694cbfc5aac7079e78a7572bc94 294 SUPERFAMILY SSF51679 2 291 1.83E-47 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_23655 935e1694cbfc5aac7079e78a7572bc94 294 Gene3D G3DSA:3.20.20.30 18 292 5.6E-51 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 186 1.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 202 1.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 214 1.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 Gene3D G3DSA:3.40.50.12740 18 232 6.6E-67 T 12-10-2018 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 SMART SM00421 169 226 7.7E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 ProSitePatterns PS00622 LuxR-type HTH domain signature. 186 213 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 SUPERFAMILY SSF52172 16 202 7.7E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_26450 008367290a28545ec3ff5dc4c9125649 236 SMART SM00448 18 131 1.1E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 Pfam PF00196 Bacterial regulatory proteins, luxR family 170 226 9.6E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26450 008367290a28545ec3ff5dc4c9125649 236 Pfam PF00072 Response regulator receiver domain 20 132 6.2E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Gene3D G3DSA:3.30.300.30 614 711 2.0E-26 T 12-10-2018 AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 SUPERFAMILY SSF47336 719 790 6.41E-14 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Pfam PF13193 AMP-binding enzyme C-terminal domain 627 699 1.1E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Gene3D G3DSA:3.40.50.12780 200 613 2.7E-112 T 12-10-2018 AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 234 643 2.6E-111 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Pfam PF00975 Thioesterase domain 816 1047 2.6E-21 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Gene3D G3DSA:3.40.50.1820 807 1052 6.2E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Gene3D G3DSA:3.30.559.30 3 198 8.4E-9 T 12-10-2018 AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Pfam PF00501 AMP-binding enzyme 213 619 3.6E-86 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 SUPERFAMILY SSF53474 797 1049 1.71E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Pfam PF00550 Phosphopantetheine attachment site 728 788 1.2E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 SUPERFAMILY SSF56801 171 740 7.98E-139 T 12-10-2018 AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 ProSitePatterns PS00455 Putative AMP-binding domain signature. 359 370 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 Gene3D G3DSA:1.10.1200.10 716 798 1.9E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18490 c6cf493e591887a573f6f2511b48467c 1062 SUPERFAMILY SSF52777 17 183 4.11E-8 T 12-10-2018 AFR_03725 785980457c05a84feaae406387195fb1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03725 785980457c05a84feaae406387195fb1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03725 785980457c05a84feaae406387195fb1 200 SUPERFAMILY SSF48498 105 198 6.43E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_03725 785980457c05a84feaae406387195fb1 200 SUPERFAMILY SSF46689 6 81 9.75E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03725 785980457c05a84feaae406387195fb1 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 9.0E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03725 785980457c05a84feaae406387195fb1 200 Gene3D G3DSA:1.10.357.10 3 200 8.7E-44 T 12-10-2018 AFR_35565 18f0124f218e74dff1d443b3727ef3d1 315 Gene3D G3DSA:3.40.50.1100 51 147 8.2E-89 T 12-10-2018 AFR_35565 18f0124f218e74dff1d443b3727ef3d1 315 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 303 2.4E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_35565 18f0124f218e74dff1d443b3727ef3d1 315 SUPERFAMILY SSF53686 4 307 3.8E-75 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_35565 18f0124f218e74dff1d443b3727ef3d1 315 Gene3D G3DSA:3.40.50.1100 17 306 8.2E-89 T 12-10-2018 AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 Pfam PF07731 Multicopper oxidase 398 506 3.0E-20 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 Pfam PF07732 Multicopper oxidase 81 207 6.1E-18 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 SUPERFAMILY SSF49503 45 208 2.63E-28 T 12-10-2018 IPR008972 Cupredoxin AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 SUPERFAMILY SSF49503 393 506 9.12E-28 T 12-10-2018 IPR008972 Cupredoxin AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 SUPERFAMILY SSF49503 211 338 2.13E-23 T 12-10-2018 IPR008972 Cupredoxin AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 ProSitePatterns PS00080 Multicopper oxidases signature 2. 489 500 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 Gene3D G3DSA:2.60.40.420 377 507 9.8E-43 T 12-10-2018 IPR008972 Cupredoxin AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 Gene3D G3DSA:2.60.40.420 41 119 2.8E-16 T 12-10-2018 IPR008972 Cupredoxin AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 Gene3D G3DSA:2.60.40.420 120 204 6.1E-26 T 12-10-2018 IPR008972 Cupredoxin AFR_33550 a40ebb804fe0171d77347c218a8915cb 507 Gene3D G3DSA:2.60.40.420 205 376 2.5E-52 T 12-10-2018 IPR008972 Cupredoxin AFR_02395 64f6c4c152a40a43b46732513b71126d 517 SMART SM00220 12 269 8.9E-59 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_02395 64f6c4c152a40a43b46732513b71126d 517 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_02395 64f6c4c152a40a43b46732513b71126d 517 Gene3D G3DSA:3.30.200.20 2 90 2.9E-25 T 12-10-2018 AFR_02395 64f6c4c152a40a43b46732513b71126d 517 Pfam PF00069 Protein kinase domain 12 261 6.6E-49 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_02395 64f6c4c152a40a43b46732513b71126d 517 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_02395 64f6c4c152a40a43b46732513b71126d 517 Gene3D G3DSA:1.10.510.10 91 271 8.7E-42 T 12-10-2018 AFR_02395 64f6c4c152a40a43b46732513b71126d 517 SUPERFAMILY SSF56112 9 268 1.24E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_17690 b1012a7fd74380ccd79db327799f2c13 465 SUPERFAMILY SSF53383 47 457 7.03E-82 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_17690 b1012a7fd74380ccd79db327799f2c13 465 Gene3D G3DSA:3.40.640.10 96 352 1.5E-117 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_17690 b1012a7fd74380ccd79db327799f2c13 465 Pfam PF00202 Aminotransferase class-III 59 438 1.1E-43 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_17690 b1012a7fd74380ccd79db327799f2c13 465 Gene3D G3DSA:3.90.1150.10 30 443 1.5E-117 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_22400 e511c13a39dc4fce0d0cc536a3c4fc55 135 Gene3D G3DSA:3.40.50.620 1 132 5.6E-20 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_22400 e511c13a39dc4fce0d0cc536a3c4fc55 135 Pfam PF00582 Universal stress protein family 2 132 7.5E-16 T 12-10-2018 IPR006016 UspA AFR_22400 e511c13a39dc4fce0d0cc536a3c4fc55 135 SUPERFAMILY SSF52402 2 132 1.34E-20 T 12-10-2018 AFR_22400 e511c13a39dc4fce0d0cc536a3c4fc55 135 PRINTS PR01438 Universal stress protein signature 93 105 8.5E-7 T 12-10-2018 IPR006015 Universal stress protein A AFR_22400 e511c13a39dc4fce0d0cc536a3c4fc55 135 PRINTS PR01438 Universal stress protein signature 111 133 8.5E-7 T 12-10-2018 IPR006015 Universal stress protein A AFR_05400 e0e2c0bea3f0be99ebe5924b261baf9f 277 Pfam PF12811 Bax inhibitor 1 like 5 274 4.6E-85 T 12-10-2018 IPR010539 Protein of unknown function UCP009160 AFR_05400 e0e2c0bea3f0be99ebe5924b261baf9f 277 PIRSF PIRSF009160 1 277 2.4E-78 T 12-10-2018 IPR010539 Protein of unknown function UCP009160 AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 243 6.2E-54 T 12-10-2018 AFR_18120 62174788e2b9914009e5ab60f00b0113 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_18120 62174788e2b9914009e5ab60f00b0113 250 Gene3D G3DSA:3.40.50.720 1 247 4.2E-77 T 12-10-2018 AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.3E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.3E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.3E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.3E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.3E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.3E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18120 62174788e2b9914009e5ab60f00b0113 250 SUPERFAMILY SSF51735 3 246 5.27E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40755 05f57c7015eef05d732fa816399a45ed 151 Gene3D G3DSA:3.40.50.620 14 151 1.7E-20 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_40755 05f57c7015eef05d732fa816399a45ed 151 SUPERFAMILY SSF52402 15 151 2.09E-22 T 12-10-2018 AFR_40755 05f57c7015eef05d732fa816399a45ed 151 PRINTS PR01438 Universal stress protein signature 12 30 3.6E-5 T 12-10-2018 IPR006015 Universal stress protein A AFR_40755 05f57c7015eef05d732fa816399a45ed 151 PRINTS PR01438 Universal stress protein signature 129 151 3.6E-5 T 12-10-2018 IPR006015 Universal stress protein A AFR_40755 05f57c7015eef05d732fa816399a45ed 151 Pfam PF00582 Universal stress protein family 15 151 7.8E-20 T 12-10-2018 IPR006016 UspA AFR_22025 ad7e78c49574e0a06dae99d2f3fc08dc 240 Gene3D G3DSA:1.10.287.130 41 94 3.8E-18 T 12-10-2018 AFR_22025 ad7e78c49574e0a06dae99d2f3fc08dc 240 Gene3D G3DSA:3.30.565.10 95 235 3.8E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_22025 ad7e78c49574e0a06dae99d2f3fc08dc 240 SUPERFAMILY SSF55874 110 237 2.36E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_22025 ad7e78c49574e0a06dae99d2f3fc08dc 240 SMART SM00387 137 238 3.9E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36310 9fb86114dec3dc21535729af7fee5412 119 Gene3D G3DSA:2.30.30.790 2 116 7.1E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 2.0E-47 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 PIRSF PIRSF002191 1 119 9.1E-50 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.176 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 Pfam PF01245 Ribosomal protein L19 4 111 1.0E-47 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 SUPERFAMILY SSF50104 1 115 9.73E-46 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFR_36310 9fb86114dec3dc21535729af7fee5412 119 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.2E-40 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.2E-40 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36310 9fb86114dec3dc21535729af7fee5412 119 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.2E-40 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_11280 736dff465d8240f97a8d65b6a0e2a20c 506 Gene3D G3DSA:3.40.50.410 320 493 2.9E-6 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_11280 736dff465d8240f97a8d65b6a0e2a20c 506 SUPERFAMILY SSF140864 10 332 7.19E-38 T 12-10-2018 IPR037214 TROVE domain superfamily AFR_11280 736dff465d8240f97a8d65b6a0e2a20c 506 Pfam PF05731 TROVE domain 214 311 7.8E-15 T 12-10-2018 IPR008858 TROVE domain GO:0003723 AFR_11280 736dff465d8240f97a8d65b6a0e2a20c 506 SUPERFAMILY SSF53300 334 494 3.34E-12 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 SMART SM00490 571 652 4.1E-11 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 Gene3D G3DSA:3.40.50.300 312 486 7.9E-39 T 12-10-2018 AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 Pfam PF13091 PLD-like domain 156 277 3.2E-10 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 SMART SM00487 318 507 4.6E-11 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 Pfam PF11907 Domain of unknown function (DUF3427) 849 1018 4.3E-23 T 12-10-2018 IPR021835 Protein of unknown function DUF3427 AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 Pfam PF04851 Type III restriction enzyme, res subunit 321 472 7.5E-32 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 Gene3D G3DSA:3.40.50.300 521 683 1.1E-31 T 12-10-2018 AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 Gene3D G3DSA:3.30.870.10 139 299 1.8E-27 T 12-10-2018 AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 Pfam PF00271 Helicase conserved C-terminal domain 555 650 4.3E-11 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 SUPERFAMILY SSF52540 375 666 2.84E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42115 a6ba1c3dec4d36f213346567e89c1971 1025 SUPERFAMILY SSF56024 143 279 1.76E-6 T 12-10-2018 AFR_08825 978625ee88780ab158a2fb06c3ff5158 283 Gene3D G3DSA:3.40.50.150 32 269 9.7E-35 T 12-10-2018 AFR_08825 978625ee88780ab158a2fb06c3ff5158 283 SUPERFAMILY SSF53335 13 220 1.44E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_08825 978625ee88780ab158a2fb06c3ff5158 283 Pfam PF08241 Methyltransferase domain 51 141 2.2E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_07945 c26480e6b62777df076d6f7650b85641 116 SUPERFAMILY SSF54197 2 111 4.25E-34 T 12-10-2018 IPR036265 HIT-like superfamily AFR_07945 c26480e6b62777df076d6f7650b85641 116 PRINTS PR00332 Histidine triad family signature 27 45 5.1E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_07945 c26480e6b62777df076d6f7650b85641 116 PRINTS PR00332 Histidine triad family signature 6 22 5.1E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_07945 c26480e6b62777df076d6f7650b85641 116 PRINTS PR00332 Histidine triad family signature 95 105 5.1E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_07945 c26480e6b62777df076d6f7650b85641 116 Pfam PF01230 HIT domain 13 108 6.2E-25 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_07945 c26480e6b62777df076d6f7650b85641 116 Gene3D G3DSA:3.30.428.10 1 116 5.3E-36 T 12-10-2018 IPR036265 HIT-like superfamily AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 SUPERFAMILY SSF54427 175 283 3.64E-11 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 Pfam PF04542 Sigma-70 region 2 11 74 5.2E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 SUPERFAMILY SSF88659 98 160 2.8E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 159 1.6E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 Gene3D G3DSA:3.10.450.50 173 288 7.4E-12 T 12-10-2018 AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 Pfam PF12680 SnoaL-like domain 182 275 2.8E-6 T 12-10-2018 IPR037401 SnoaL-like domain AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 Gene3D G3DSA:1.10.1740.10 2 95 3.3E-23 T 12-10-2018 AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 Gene3D G3DSA:1.10.10.10 99 160 2.9E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 SUPERFAMILY SSF88946 4 77 2.75E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_25140 64fc2ed9cf5270a7e9673314c457ec51 298 Pfam PF08281 Sigma-70, region 4 104 156 4.3E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_13065 a18afd48b677db70999d4885bf9b6e79 370 Pfam PF13407 Periplasmic binding protein domain 74 325 3.9E-14 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_13065 a18afd48b677db70999d4885bf9b6e79 370 SUPERFAMILY SSF53822 75 332 4.99E-23 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_13065 a18afd48b677db70999d4885bf9b6e79 370 Gene3D G3DSA:3.40.50.2300 179 341 3.3E-11 T 12-10-2018 AFR_13065 a18afd48b677db70999d4885bf9b6e79 370 Gene3D G3DSA:3.40.50.2300 72 178 8.7E-9 T 12-10-2018 AFR_20745 6d5080d28939c5571cb46c33be5a2e0a 327 Gene3D G3DSA:3.40.50.720 4 314 4.6E-92 T 12-10-2018 AFR_20745 6d5080d28939c5571cb46c33be5a2e0a 327 SUPERFAMILY SSF51735 3 146 3.94E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_20745 6d5080d28939c5571cb46c33be5a2e0a 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 118 4.7E-27 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_20745 6d5080d28939c5571cb46c33be5a2e0a 327 SUPERFAMILY SSF55347 124 273 1.55E-22 T 12-10-2018 AFR_20745 6d5080d28939c5571cb46c33be5a2e0a 327 Gene3D G3DSA:3.30.360.10 137 265 4.6E-92 T 12-10-2018 AFR_04240 1cad5846206851a56b6fcdc66aa731c9 365 Pfam PF00144 Beta-lactamase 31 353 6.6E-60 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_04240 1cad5846206851a56b6fcdc66aa731c9 365 Gene3D G3DSA:3.40.710.10 27 361 3.1E-98 T 12-10-2018 AFR_04240 1cad5846206851a56b6fcdc66aa731c9 365 SUPERFAMILY SSF56601 28 346 1.18E-74 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Pfam PF04561 RNA polymerase Rpb2, domain 2 161 347 6.4E-29 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Pfam PF04565 RNA polymerase Rpb2, domain 3 406 474 4.8E-28 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 21 1107 12.264 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Pfam PF00562 RNA polymerase Rpb2, domain 6 611 1029 3.4E-159 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 ProSitePatterns PS01166 RNA polymerases beta chain signature. 850 862 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Gene3D G3DSA:2.30.150.10 487 554 0.0 T 12-10-2018 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Gene3D G3DSA:2.40.270.10 24 1007 0.0 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Pfam PF04563 RNA polymerase beta subunit 35 391 2.6E-21 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 SUPERFAMILY SSF64484 20 1115 0.0 T 12-10-2018 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Gene3D G3DSA:3.90.1110.10 166 341 0.0 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Gene3D G3DSA:2.40.50.150 722 848 0.0 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Gene3D G3DSA:3.90.1800.10 1016 1070 2.3E-10 T 12-10-2018 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Pfam PF10385 RNA polymerase beta subunit external 1 domain 484 550 3.6E-24 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 234 824 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Gene3D G3DSA:2.40.50.100 612 686 0.0 T 12-10-2018 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Gene3D G3DSA:3.90.1100.10 26 611 0.0 T 12-10-2018 AFR_04460 3ff7fdbf0576a1eec06518261a48179b 1146 Pfam PF04560 RNA polymerase Rpb2, domain 7 1031 1105 2.7E-26 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 6.5E-20 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 SUPERFAMILY SSF55666 159 240 1.96E-20 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 Gene3D G3DSA:3.30.230.70 11 242 4.8E-54 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 Hamap MF_00564 Ribonuclease PH [rph]. 12 241 42.082 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 SUPERFAMILY SSF54211 3 184 2.38E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 Pfam PF03725 3' exoribonuclease family, domain 2 165 225 1.5E-9 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFR_06370 d426398b81c08cbbe77a65c78ac2bbec 242 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 240 1.1E-109 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 SUPERFAMILY SSF50249 44 111 1.23E-6 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 Gene3D G3DSA:3.40.50.300 118 400 9.8E-116 T 12-10-2018 AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 TIGRFAM TIGR00767 rho: transcription termination factor Rho 40 399 3.7E-160 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 SMART SM00382 154 339 1.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 Pfam PF07497 Rho termination factor, RNA-binding domain 46 111 8.2E-14 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 403 168.152 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 Gene3D G3DSA:2.40.50.140 12 115 1.1E-14 T 12-10-2018 AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 SUPERFAMILY SSF52540 105 354 1.18E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01140 84bbd15f826bc475f1840f7e6e02a51c 405 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 143 347 6.3E-22 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_27060 452eb4d5c3ae8aa747fd2249900ea879 534 PRINTS PR00723 Subtilisin serine protease family (S8) signature 330 346 5.5E-11 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_27060 452eb4d5c3ae8aa747fd2249900ea879 534 PRINTS PR00723 Subtilisin serine protease family (S8) signature 86 105 5.5E-11 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_27060 452eb4d5c3ae8aa747fd2249900ea879 534 PRINTS PR00723 Subtilisin serine protease family (S8) signature 129 142 5.5E-11 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_27060 452eb4d5c3ae8aa747fd2249900ea879 534 Gene3D G3DSA:3.40.50.200 73 392 1.3E-71 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_27060 452eb4d5c3ae8aa747fd2249900ea879 534 Pfam PF00082 Subtilase family 86 375 5.1E-41 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_27060 452eb4d5c3ae8aa747fd2249900ea879 534 SUPERFAMILY SSF52743 83 389 3.8E-65 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 Gene3D G3DSA:1.10.10.10 829 908 7.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 SMART SM00382 28 208 1.3E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 SMART SM00421 851 908 4.0E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 SUPERFAMILY SSF46894 849 905 1.73E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 Pfam PF13191 AAA ATPase domain 8 157 3.0E-17 T 12-10-2018 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 854 868 5.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 884 896 5.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 868 884 5.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 ProSitePatterns PS00622 LuxR-type HTH domain signature. 868 895 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 Pfam PF00196 Bacterial regulatory proteins, luxR family 853 904 2.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12325 2601091ae0e3de9e63f4d300f4af8f76 914 SUPERFAMILY SSF52540 8 230 3.07E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32195 96609b0684c513a643abf628b9806c8d 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.6E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32195 96609b0684c513a643abf628b9806c8d 189 Gene3D G3DSA:1.10.357.10 1 188 3.5E-52 T 12-10-2018 AFR_32195 96609b0684c513a643abf628b9806c8d 189 SUPERFAMILY SSF48498 75 184 1.78E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_32195 96609b0684c513a643abf628b9806c8d 189 SUPERFAMILY SSF46689 3 79 4.21E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_32195 96609b0684c513a643abf628b9806c8d 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32195 96609b0684c513a643abf628b9806c8d 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 Gene3D G3DSA:1.10.10.10 1 94 2.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 83 3.3E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 SMART SM01043 98 236 6.8E-30 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 Pfam PF03704 Bacterial transcriptional activator domain 99 233 1.1E-24 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 SUPERFAMILY SSF48452 93 241 1.83E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 Gene3D G3DSA:1.25.40.10 96 250 5.0E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 SUPERFAMILY SSF46894 21 85 4.82E-9 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 PRINTS PR00364 Disease resistance protein signature 412 426 2.2E-6 T 12-10-2018 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 PRINTS PR00364 Disease resistance protein signature 265 280 2.2E-6 T 12-10-2018 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 PRINTS PR00364 Disease resistance protein signature 333 347 2.2E-6 T 12-10-2018 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 SMART SM00862 12 91 6.4E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 Pfam PF00931 NB-ARC domain 256 429 1.4E-6 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_28225 153e61e27cdbdc3b6514b339c950529d 543 SUPERFAMILY SSF52540 242 444 2.09E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12680 5be49fc46347e853ab357e10d3ef97de 304 Pfam PF04072 Leucine carboxyl methyltransferase 31 205 3.1E-41 T 12-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 AFR_12680 5be49fc46347e853ab357e10d3ef97de 304 SUPERFAMILY SSF53335 27 288 6.09E-53 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_12680 5be49fc46347e853ab357e10d3ef97de 304 Gene3D G3DSA:3.40.50.150 20 288 9.3E-63 T 12-10-2018 AFR_12680 5be49fc46347e853ab357e10d3ef97de 304 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 29 278 8.4E-62 T 12-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 SMART SM00052 640 886 1.4E-124 T 12-10-2018 IPR001633 EAL domain AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 SMART SM00091 346 412 8.7E-5 T 12-10-2018 IPR000014 PAS domain AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 Pfam PF08448 PAS fold 354 459 1.7E-5 T 12-10-2018 IPR013656 PAS fold-4 AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 Gene3D G3DSA:3.30.450.20 334 457 3.7E-16 T 12-10-2018 AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 Gene3D G3DSA:3.20.20.450 643 895 3.0E-103 T 12-10-2018 IPR035919 EAL domain superfamily AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 SUPERFAMILY SSF55073 476 632 6.28E-44 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 342 467 6.9E-14 T 12-10-2018 IPR000014 PAS domain AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 SUPERFAMILY SSF55785 337 457 5.5E-16 T 12-10-2018 IPR035965 PAS domain superfamily AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 SMART SM00267 460 630 2.0E-58 T 12-10-2018 IPR000160 GGDEF domain AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 SUPERFAMILY SSF141868 646 894 1.29E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 Pfam PF00990 Diguanylate cyclase, GGDEF domain 471 623 3.5E-44 T 12-10-2018 IPR000160 GGDEF domain AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 Pfam PF00563 EAL domain 646 881 2.6E-72 T 12-10-2018 IPR001633 EAL domain AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 Gene3D G3DSA:3.30.70.270 465 642 1.4E-54 T 12-10-2018 AFR_21870 72c010535e0ccb2b25a7dc13495ef972 905 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 468 624 7.7E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 31 190 4.5E-30 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 Gene3D G3DSA:1.10.1040.10 287 493 6.5E-62 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 221 446 8.3E-64 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 Gene3D G3DSA:3.40.50.720 13 286 2.1E-86 T 12-10-2018 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 223 235 - T 12-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 SUPERFAMILY SSF51735 16 286 1.14E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 PRINTS PR00084 Mannitol dehydrogenase signature 253 268 7.0E-18 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 PRINTS PR00084 Mannitol dehydrogenase signature 181 194 7.0E-18 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 PRINTS PR00084 Mannitol dehydrogenase signature 223 236 7.0E-18 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 PRINTS PR00084 Mannitol dehydrogenase signature 32 42 7.0E-18 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25255 f9f92bc34501d75848c7d467c67d79f9 494 SUPERFAMILY SSF48179 290 492 5.44E-48 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 ProSitePatterns PS00517 Ribonuclease III family signature. 48 56 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 SUPERFAMILY SSF54768 123 235 6.91E-25 T 12-10-2018 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 Pfam PF00035 Double-stranded RNA binding motif 169 234 2.6E-14 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 21 233 8.2E-67 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 SUPERFAMILY SSF69065 8 171 2.96E-45 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 Pfam PF14622 Ribonuclease-III-like 25 153 6.3E-36 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 Hamap MF_00104 Ribonuclease 3 [rnc]. 15 231 28.631 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 Gene3D G3DSA:3.30.160.20 168 237 2.8E-20 T 12-10-2018 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 Gene3D G3DSA:1.10.1520.10 9 161 5.0E-48 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 SMART SM00535 26 162 1.5E-51 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFR_36525 936ef5873ab90a621f461069ecf64e8d 261 SMART SM00358 169 235 2.3E-17 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain AFR_02385 d3bf7746f8a87de7114f1093545d5680 136 Gene3D G3DSA:3.40.250.10 11 136 3.8E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_02385 d3bf7746f8a87de7114f1093545d5680 136 Pfam PF00581 Rhodanese-like domain 34 131 3.3E-12 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_02385 d3bf7746f8a87de7114f1093545d5680 136 SUPERFAMILY SSF52821 21 135 3.93E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_02385 d3bf7746f8a87de7114f1093545d5680 136 SMART SM00450 31 134 9.8E-17 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_37155 ed7eb5384abecb936e80934dcba6fd2e 309 Gene3D G3DSA:3.40.50.720 2 301 9.3E-71 T 12-10-2018 AFR_37155 ed7eb5384abecb936e80934dcba6fd2e 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 4.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37155 ed7eb5384abecb936e80934dcba6fd2e 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 4.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37155 ed7eb5384abecb936e80934dcba6fd2e 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 4.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37155 ed7eb5384abecb936e80934dcba6fd2e 309 SUPERFAMILY SSF51735 10 251 2.06E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37155 ed7eb5384abecb936e80934dcba6fd2e 309 Pfam PF00106 short chain dehydrogenase 17 215 5.0E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SUPERFAMILY SSF55874 362 527 1.57E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Gene3D G3DSA:3.30.565.10 380 532 3.2E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Pfam PF01590 GAF domain 17 149 3.3E-13 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Gene3D G3DSA:1.10.287.130 295 374 1.0E-20 T 12-10-2018 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Gene3D G3DSA:3.30.450.40 2 158 1.2E-22 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SMART SM00091 163 230 2.0E-10 T 12-10-2018 IPR000014 PAS domain AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SMART SM00387 417 529 3.5E-41 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Gene3D G3DSA:3.30.450.20 160 282 1.3E-25 T 12-10-2018 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SMART SM00065 13 159 1.5E-18 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SUPERFAMILY SSF55785 174 288 2.09E-23 T 12-10-2018 IPR035965 PAS domain superfamily AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Pfam PF00989 PAS fold 164 277 3.4E-16 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 418 527 1.2E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 Pfam PF00512 His Kinase A (phospho-acceptor) domain 307 373 9.9E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SMART SM00388 307 373 8.0E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SUPERFAMILY SSF47384 295 374 3.14E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 SUPERFAMILY SSF55781 16 157 1.05E-25 T 12-10-2018 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 162 284 1.3E-20 T 12-10-2018 IPR000014 PAS domain AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 507 4.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 482 4.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 4.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_12515 f3a57982ebc31e65559ffd1484f14488 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 526 4.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20470 a69e191d61ffe39a596a8cc7ba6e3315 367 SUPERFAMILY SSF51679 1 333 2.88E-69 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_20470 a69e191d61ffe39a596a8cc7ba6e3315 367 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 1.0E-215 T 12-10-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative AFR_20470 a69e191d61ffe39a596a8cc7ba6e3315 367 Pfam PF00296 Luciferase-like monooxygenase 1 293 1.6E-54 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_20470 a69e191d61ffe39a596a8cc7ba6e3315 367 Gene3D G3DSA:3.20.20.30 1 340 5.1E-66 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 PRINTS PR00133 Glycosyl hydrolase family 3 signature 159 175 3.9E-8 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 PRINTS PR00133 Glycosyl hydrolase family 3 signature 70 89 3.9E-8 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 349 692 3.2E-53 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Gene3D G3DSA:2.60.120.260 810 943 8.6E-24 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Gene3D G3DSA:2.60.40.10 696 809 7.7E-30 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 SUPERFAMILY SSF50405 435 535 4.58E-9 T 12-10-2018 IPR008999 Actin-crosslinking AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Gene3D G3DSA:3.20.20.300 22 695 4.3E-197 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Gene3D G3DSA:2.60.120.380 425 545 4.3E-197 T 12-10-2018 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Pfam PF03422 Carbohydrate binding module (family 6) 831 933 1.6E-17 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Gene3D G3DSA:3.40.50.1700 342 659 4.3E-197 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 SMART SM01217 729 799 3.6E-25 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Pfam PF14310 Fibronectin type III-like domain 729 798 5.4E-20 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 50 308 6.8E-40 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 SUPERFAMILY SSF51445 8 348 6.32E-81 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 SUPERFAMILY SSF52279 349 695 3.27E-44 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 SUPERFAMILY SSF49785 820 942 8.84E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_17600 3cc6c09804a2137ae6dd2eb62e16b62b 944 SMART SM00606 817 944 9.7E-22 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 SUPERFAMILY SSF46894 142 211 6.46E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 Pfam PF00072 Response regulator receiver domain 1 113 3.8E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 SMART SM00448 1 112 2.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 SMART SM00421 147 204 6.7E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 1.2E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 Gene3D G3DSA:3.40.50.12740 1 210 1.1E-70 T 12-10-2018 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24600 6a47d0199f247f695b46b94509b854d1 219 SUPERFAMILY SSF52172 1 132 9.96E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Gene3D G3DSA:3.40.50.300 326 482 1.8E-26 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Gene3D G3DSA:1.25.40.10 166 325 6.1E-33 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Gene3D G3DSA:1.25.40.10 747 840 1.3E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SUPERFAMILY SSF48452 166 329 1.08E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SMART SM00862 86 163 3.1E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SMART SM00028 816 849 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SMART SM00028 776 809 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SMART SM00028 896 929 1.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SMART SM00028 936 969 170.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Pfam PF13560 Helix-turn-helix domain 4 61 8.7E-14 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SUPERFAMILY SSF48452 769 964 4.86E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SUPERFAMILY SSF47413 3 60 1.42E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 PRINTS PR00364 Disease resistance protein signature 438 452 2.7E-7 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 PRINTS PR00364 Disease resistance protein signature 360 375 2.7E-7 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 PRINTS PR00364 Disease resistance protein signature 526 540 2.7E-7 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Gene3D G3DSA:1.10.10.10 64 165 1.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Pfam PF00486 Transcriptional regulatory protein, C terminal 95 163 2.1E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SMART SM00530 7 63 2.2E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SUPERFAMILY SSF46894 71 163 8.79E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SUPERFAMILY SSF52540 344 593 7.65E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 SMART SM01043 169 314 2.5E-32 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Pfam PF13424 Tetratricopeptide repeat 901 966 3.5E-9 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Pfam PF13424 Tetratricopeptide repeat 776 843 2.5E-9 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Gene3D G3DSA:1.10.260.40 2 63 7.2E-12 T 12-10-2018 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Pfam PF03704 Bacterial transcriptional activator domain 169 314 1.5E-27 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Gene3D G3DSA:1.25.40.10 841 982 3.3E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25950 794b862f6a0cb94944f3b09fd55da9cd 985 Pfam PF00931 NB-ARC domain 344 538 5.7E-12 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_41270 4b2b6a1ee5d2bee2478c5a81b94278cf 163 Pfam PF02542 YgbB family 7 156 2.6E-46 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFR_41270 4b2b6a1ee5d2bee2478c5a81b94278cf 163 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 40 55 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFR_41270 4b2b6a1ee5d2bee2478c5a81b94278cf 163 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 6 158 30.313 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFR_41270 4b2b6a1ee5d2bee2478c5a81b94278cf 163 SUPERFAMILY SSF69765 6 158 2.88E-50 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFR_41270 4b2b6a1ee5d2bee2478c5a81b94278cf 163 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 7 157 1.6E-46 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFR_41270 4b2b6a1ee5d2bee2478c5a81b94278cf 163 Gene3D G3DSA:3.30.1330.50 2 163 8.8E-57 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFR_06005 ee639bf2899f4bbf9e2ecf2bac8d7901 447 Pfam PF07690 Major Facilitator Superfamily 245 417 2.0E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_06005 ee639bf2899f4bbf9e2ecf2bac8d7901 447 Pfam PF07690 Major Facilitator Superfamily 17 244 3.1E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_06005 ee639bf2899f4bbf9e2ecf2bac8d7901 447 Gene3D G3DSA:1.20.1250.20 223 419 3.9E-19 T 12-10-2018 AFR_06005 ee639bf2899f4bbf9e2ecf2bac8d7901 447 Gene3D G3DSA:1.20.1250.20 5 199 3.9E-25 T 12-10-2018 AFR_06005 ee639bf2899f4bbf9e2ecf2bac8d7901 447 SUPERFAMILY SSF103473 7 418 1.83E-58 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_11635 03347b64cd18895ef36744c8b64f90f1 392 Gene3D G3DSA:3.90.1150.10 239 360 1.9E-5 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 121 7.7E-10 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 472 493 2.6E-5 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 2.6E-5 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 352 374 2.6E-5 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 Pfam PF00361 Proton-conducting membrane transporter 135 401 1.3E-76 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 2.4E-45 T 12-10-2018 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 2.4E-45 T 12-10-2018 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 2.4E-45 T 12-10-2018 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 2.4E-45 T 12-10-2018 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 2.4E-45 T 12-10-2018 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 2.4E-45 T 12-10-2018 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 268 2.4E-45 T 12-10-2018 AFR_04265 528864beb1fb4142ee22ee6154c06860 633 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 15 622 2.8E-147 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 SMART SM00437 286 555 4.1E-115 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 323 337 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Pfam PF13368 Topoisomerase C-terminal repeat 702 755 1.1E-17 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Pfam PF13368 Topoisomerase C-terminal repeat 756 809 3.5E-17 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Pfam PF13368 Topoisomerase C-terminal repeat 821 873 3.4E-19 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Pfam PF13368 Topoisomerase C-terminal repeat 638 689 2.4E-7 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Gene3D G3DSA:1.10.290.10 294 422 2.4E-170 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Pfam PF01751 Toprim domain 12 133 8.6E-27 T 12-10-2018 IPR006171 TOPRIM domain AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Hamap MF_00952 DNA topoisomerase 1 [topA]. 10 776 53.027 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Pfam PF01131 DNA topoisomerase 147 592 3.2E-118 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 SMART SM00436 124 212 2.7E-45 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 12 662 5.5E-241 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Gene3D G3DSA:2.70.20.10 204 502 2.4E-170 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 328 337 9.6E-34 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 518 532 9.6E-34 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 98 111 9.6E-34 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 407 423 9.6E-34 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 182 200 9.6E-34 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 SMART SM00493 10 124 1.0E-35 T 12-10-2018 IPR006171 TOPRIM domain AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Gene3D G3DSA:3.40.50.140 9 154 9.2E-59 T 12-10-2018 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 Gene3D G3DSA:1.10.460.10 155 595 2.4E-170 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFR_01905 98e623e19bea6a8a9295c00b8d808f3d 940 SUPERFAMILY SSF56712 10 596 9.29E-177 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFR_36080 0643ab92a3277928c9cb8693250ae064 174 SUPERFAMILY SSF46785 87 155 7.13E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_36080 0643ab92a3277928c9cb8693250ae064 174 Pfam PF12840 Helix-turn-helix domain 96 149 1.9E-6 T 12-10-2018 AFR_36080 0643ab92a3277928c9cb8693250ae064 174 Gene3D G3DSA:1.10.10.10 79 170 6.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07340 22eb7b983162f5eb9454e75083f7a22e 533 SUPERFAMILY SSF52317 272 451 2.44E-13 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_07340 22eb7b983162f5eb9454e75083f7a22e 533 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 183 3.5E-13 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFR_07340 22eb7b983162f5eb9454e75083f7a22e 533 SUPERFAMILY SSF52540 6 183 7.09E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07340 22eb7b983162f5eb9454e75083f7a22e 533 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 278 436 1.5E-7 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFR_07340 22eb7b983162f5eb9454e75083f7a22e 533 Gene3D G3DSA:3.40.50.300 6 186 2.1E-22 T 12-10-2018 AFR_35240 c1341b691a5e50d43665504a4af4d028 443 Pfam PF13360 PQQ-like domain 194 334 2.3E-9 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_35240 c1341b691a5e50d43665504a4af4d028 443 SUPERFAMILY SSF50998 86 339 1.7E-12 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_35240 c1341b691a5e50d43665504a4af4d028 443 Gene3D G3DSA:2.130.10.10 50 375 5.9E-17 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 Gene3D G3DSA:1.10.340.30 49 160 1.3E-68 T 12-10-2018 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 PIRSF PIRSF001435 29 239 4.5E-43 T 12-10-2018 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 SMART SM00525 214 234 8.6E-5 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 Pfam PF00633 Helix-hairpin-helix motif 127 154 9.0E-8 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 Hamap MF_00942 Endonuclease III [nth]. 28 237 34.653 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 ProSitePatterns PS01155 Endonuclease III family signature. 130 159 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 TIGRFAM TIGR01083 nth: endonuclease III 32 222 1.3E-71 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 215 231 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 SMART SM00478 66 213 8.3E-49 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 62 196 6.8E-18 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 SUPERFAMILY SSF48150 34 243 9.11E-61 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_41600 2581ebe8da5d2665f93cc5d42f94758e 278 Gene3D G3DSA:1.10.1670.10 43 231 1.3E-68 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFR_20790 fc9104637aec443dde15cefe9554609b 562 Gene3D G3DSA:3.40.605.10 92 317 2.4E-26 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_20790 fc9104637aec443dde15cefe9554609b 562 SUPERFAMILY SSF53720 84 525 1.11E-54 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_20790 fc9104637aec443dde15cefe9554609b 562 Pfam PF00171 Aldehyde dehydrogenase family 94 496 1.0E-33 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_20790 fc9104637aec443dde15cefe9554609b 562 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 5 555 5.9E-248 T 12-10-2018 IPR011975 Phenylacetic acid degradation protein PaaN2 AFR_20790 fc9104637aec443dde15cefe9554609b 562 Gene3D G3DSA:3.40.309.10 318 520 3.2E-21 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 Hamap MF_00015 LexA repressor [lexA]. 11 214 30.706 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 SUPERFAMILY SSF46785 11 76 8.97E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 Pfam PF00717 Peptidase S24-like 133 197 2.9E-14 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 Gene3D G3DSA:2.10.109.10 99 214 1.4E-38 T 12-10-2018 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 141 152 2.5E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 130 140 2.5E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 169 181 2.5E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 SUPERFAMILY SSF51306 93 212 2.96E-34 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 TIGRFAM TIGR00498 lexA: repressor LexA 10 214 7.4E-61 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 Pfam PF01726 LexA DNA binding domain 10 67 3.6E-16 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 AFR_34250 14f3f9a99e74c8cc9ba442c2521b65f4 214 Gene3D G3DSA:1.10.10.10 10 77 3.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00860 4f258a06de11fde103eca4db222e8762 142 Pfam PF13474 SnoaL-like domain 7 128 2.1E-15 T 12-10-2018 IPR037401 SnoaL-like domain AFR_00860 4f258a06de11fde103eca4db222e8762 142 Gene3D G3DSA:3.10.450.50 1 142 5.1E-26 T 12-10-2018 AFR_00860 4f258a06de11fde103eca4db222e8762 142 SUPERFAMILY SSF54427 2 125 1.54E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_30640 d017358fbc377aed1c8382f13223a5bf 162 SMART SM00530 87 142 90.0 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_30640 d017358fbc377aed1c8382f13223a5bf 162 SMART SM00530 12 69 6.8E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_30640 d017358fbc377aed1c8382f13223a5bf 162 Gene3D G3DSA:1.10.260.40 1 71 2.8E-33 T 12-10-2018 AFR_30640 d017358fbc377aed1c8382f13223a5bf 162 Gene3D G3DSA:1.10.10.1930 75 162 1.0E-31 T 12-10-2018 IPR038099 BldD-like, C-terminal domain superfamily AFR_30640 d017358fbc377aed1c8382f13223a5bf 162 Pfam PF01381 Helix-turn-helix 13 69 9.4E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_30640 d017358fbc377aed1c8382f13223a5bf 162 SUPERFAMILY SSF47413 3 71 1.52E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 SMART SM00421 851 908 1.6E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 SUPERFAMILY SSF46894 844 904 3.74E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 884 896 2.1E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 868 884 2.1E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 854 868 2.1E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 Gene3D G3DSA:1.25.40.10 527 808 2.4E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 SUPERFAMILY SSF52540 8 226 2.87E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 Gene3D G3DSA:1.10.10.10 809 915 6.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 Pfam PF13191 AAA ATPase domain 10 165 1.9E-19 T 12-10-2018 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 ProSitePatterns PS00622 LuxR-type HTH domain signature. 868 895 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 SUPERFAMILY SSF48452 551 696 5.69E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_11855 73c9a0a714ef2c4f1354fd8319707d68 916 Pfam PF00196 Bacterial regulatory proteins, luxR family 853 904 7.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33940 c3a7be16c54133f584b17d07be55d3f2 731 Pfam PF07730 Histidine kinase 550 615 2.2E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_33940 c3a7be16c54133f584b17d07be55d3f2 731 Gene3D G3DSA:3.30.565.10 612 731 1.0E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33940 c3a7be16c54133f584b17d07be55d3f2 731 SUPERFAMILY SSF55874 631 730 1.78E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33940 c3a7be16c54133f584b17d07be55d3f2 731 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 655 728 5.6E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_05630 ddbe2972778b46943a7eb472747beaf2 381 SUPERFAMILY SSF53756 8 378 2.72E-57 T 12-10-2018 AFR_05630 ddbe2972778b46943a7eb472747beaf2 381 Pfam PF13439 Glycosyltransferase Family 4 21 181 8.1E-16 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_05630 ddbe2972778b46943a7eb472747beaf2 381 Pfam PF00534 Glycosyl transferases group 1 204 356 6.6E-19 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_05630 ddbe2972778b46943a7eb472747beaf2 381 Gene3D G3DSA:3.40.50.2000 19 370 3.2E-50 T 12-10-2018 AFR_05630 ddbe2972778b46943a7eb472747beaf2 381 Gene3D G3DSA:3.40.50.2000 180 360 3.2E-50 T 12-10-2018 AFR_14545 f23920944b3a673ca969f77d7c89f430 311 Pfam PF14525 AraC-binding-like domain 20 191 1.7E-20 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_14545 f23920944b3a673ca969f77d7c89f430 311 Pfam PF12833 Helix-turn-helix domain 233 311 1.2E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14545 f23920944b3a673ca969f77d7c89f430 311 Gene3D G3DSA:1.10.10.60 206 311 1.3E-27 T 12-10-2018 AFR_14545 f23920944b3a673ca969f77d7c89f430 311 SMART SM00342 227 309 3.2E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14545 f23920944b3a673ca969f77d7c89f430 311 SUPERFAMILY SSF46689 262 310 1.97E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14545 f23920944b3a673ca969f77d7c89f430 311 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 293 5.9E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_14545 f23920944b3a673ca969f77d7c89f430 311 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 309 5.9E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 Gene3D G3DSA:1.10.8.10 1 78 9.7E-19 T 12-10-2018 AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 SUPERFAMILY SSF53335 2 268 2.33E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 176 182 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 Gene3D G3DSA:3.40.50.150 79 272 1.4E-45 T 12-10-2018 AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 Pfam PF05175 Methyltransferase small domain 104 185 2.5E-10 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 4 270 5.6E-44 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 271 36.949 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFR_37405 13e8cc9d396b04261aa0160322f1293c 272 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 20 267 2.1E-63 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFR_03565 7be56908b7001b68dc330664e69e6f83 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 6.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03565 7be56908b7001b68dc330664e69e6f83 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 6.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03565 7be56908b7001b68dc330664e69e6f83 226 Gene3D G3DSA:1.10.357.10 1 179 6.6E-29 T 12-10-2018 AFR_03565 7be56908b7001b68dc330664e69e6f83 226 SUPERFAMILY SSF46689 4 77 4.39E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03565 7be56908b7001b68dc330664e69e6f83 226 Pfam PF13305 WHG domain 89 149 1.1E-6 T 12-10-2018 IPR025996 WHG domain AFR_03565 7be56908b7001b68dc330664e69e6f83 226 SUPERFAMILY SSF48498 79 149 1.42E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_03565 7be56908b7001b68dc330664e69e6f83 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 2.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 SUPERFAMILY SSF51055 28 73 1.16E-12 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 ProSitePatterns PS01095 Chitinases family 18 active site. 242 250 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 SUPERFAMILY SSF51445 127 424 8.65E-41 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 SMART SM00636 128 417 0.0042 T 12-10-2018 IPR011583 Chitinase II GO:0008061 AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 Pfam PF00704 Glycosyl hydrolases family 18 130 332 2.7E-19 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 Gene3D G3DSA:2.10.10.20 25 77 4.7E-18 T 12-10-2018 AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 SMART SM00495 26 74 5.1E-14 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_20460 61ee37957f31c1eae948f003fd5cb41b 434 Gene3D G3DSA:3.20.20.80 125 433 1.0E-54 T 12-10-2018 AFR_41925 6d819dc1cd5da0d285f1273726087d2c 320 Pfam PF01008 Initiation factor 2 subunit family 43 309 4.5E-48 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 AFR_41925 6d819dc1cd5da0d285f1273726087d2c 320 SUPERFAMILY SSF100950 2 313 1.4E-83 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_41925 6d819dc1cd5da0d285f1273726087d2c 320 Gene3D G3DSA:3.40.50.10470 175 318 2.4E-41 T 12-10-2018 AFR_41925 6d819dc1cd5da0d285f1273726087d2c 320 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 2 313 6.8E-97 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFR_41925 6d819dc1cd5da0d285f1273726087d2c 320 Gene3D G3DSA:1.20.120.1840 1 174 1.1E-40 T 12-10-2018 AFR_41925 6d819dc1cd5da0d285f1273726087d2c 320 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 29 312 2.4E-76 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 SUPERFAMILY SSF53218 202 351 1.31E-31 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 270 283 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 SMART SM00852 205 348 8.1E-22 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 Pfam PF00994 Probable molybdopterin binding domain 206 346 1.4E-20 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 SUPERFAMILY SSF63867 358 433 6.28E-13 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 Gene3D G3DSA:2.40.340.10 358 433 5.8E-11 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 Gene3D G3DSA:3.40.980.10 200 346 4.5E-84 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 Gene3D G3DSA:3.90.105.10 36 199 4.5E-84 T 12-10-2018 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 Gene3D G3DSA:2.170.190.11 57 166 4.5E-84 T 12-10-2018 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 Pfam PF03454 MoeA C-terminal region (domain IV) 361 432 7.2E-13 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 Pfam PF03453 MoeA N-terminal region (domain I and II) 16 192 8.9E-33 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_39895 ef14e7aa3a29b1e7ba8a33901685ce2d 436 SUPERFAMILY SSF63882 14 199 3.4E-38 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 161 176 4.5E-11 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 333 4.5E-11 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 337 349 4.5E-11 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 210 225 4.5E-11 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 Gene3D G3DSA:2.60.40.1730 44 227 6.0E-27 T 12-10-2018 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 SUPERFAMILY SSF63737 34 226 3.92E-35 T 12-10-2018 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 Pfam PF01433 Peptidase family M1 domain 314 456 3.4E-28 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 SUPERFAMILY SSF55486 249 465 2.93E-53 T 12-10-2018 AFR_26080 60f312c9be419b387af3d63246fe5e94 494 Gene3D G3DSA:1.10.390.60 242 460 5.1E-38 T 12-10-2018 AFR_03730 a7b11f200d08f2c44aca810ee7ecf97d 309 Gene3D G3DSA:3.40.50.1820 1 279 1.1E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_03730 a7b11f200d08f2c44aca810ee7ecf97d 309 Pfam PF12697 Alpha/beta hydrolase family 26 272 3.7E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_03730 a7b11f200d08f2c44aca810ee7ecf97d 309 SUPERFAMILY SSF53474 3 276 5.21E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_38445 a846f17071b9d1a5208942e59ec6ed48 260 Pfam PF00005 ABC transporter 36 168 7.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_38445 a846f17071b9d1a5208942e59ec6ed48 260 SMART SM00382 45 228 7.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_38445 a846f17071b9d1a5208942e59ec6ed48 260 SUPERFAMILY SSF52540 17 236 1.5E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38445 a846f17071b9d1a5208942e59ec6ed48 260 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_38445 a846f17071b9d1a5208942e59ec6ed48 260 Gene3D G3DSA:3.40.50.300 14 258 2.9E-62 T 12-10-2018 AFR_16470 8b2042a8bf0a266f7133f337b31b94e6 271 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 231 9.4E-14 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFR_16470 8b2042a8bf0a266f7133f337b31b94e6 271 Gene3D G3DSA:3.60.21.10 1 258 8.6E-29 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_16470 8b2042a8bf0a266f7133f337b31b94e6 271 SUPERFAMILY SSF56300 1 251 2.25E-42 T 12-10-2018 AFR_34470 9e01407a20fa5559911ac7540cef4221 556 Pfam PF03098 Animal haem peroxidase 108 307 3.9E-17 T 12-10-2018 IPR019791 Haem peroxidase, animal type AFR_34470 9e01407a20fa5559911ac7540cef4221 556 Gene3D G3DSA:1.10.640.10 65 325 1.2E-16 T 12-10-2018 IPR037120 Haem peroxidase domain superfamily, animal type AFR_34470 9e01407a20fa5559911ac7540cef4221 556 SUPERFAMILY SSF48113 73 538 6.95E-65 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_25350 816334a84b2d4cae0e4b440212b1f297 504 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_25350 816334a84b2d4cae0e4b440212b1f297 504 SMART SM00220 12 273 3.9E-62 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_25350 816334a84b2d4cae0e4b440212b1f297 504 SUPERFAMILY SSF56112 8 339 8.09E-69 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_25350 816334a84b2d4cae0e4b440212b1f297 504 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_25350 816334a84b2d4cae0e4b440212b1f297 504 Pfam PF00069 Protein kinase domain 12 261 3.4E-47 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_25350 816334a84b2d4cae0e4b440212b1f297 504 Gene3D G3DSA:3.30.200.20 2 95 4.1E-30 T 12-10-2018 AFR_25350 816334a84b2d4cae0e4b440212b1f297 504 Gene3D G3DSA:1.10.510.10 98 281 1.3E-37 T 12-10-2018 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 232 41.572 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 SUPERFAMILY SSF52313 6 226 3.66E-90 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 7.5E-105 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 PRINTS PR00395 Ribosomal protein S2 signature 6 24 5.0E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 PRINTS PR00395 Ribosomal protein S2 signature 37 46 5.0E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 PRINTS PR00395 Ribosomal protein S2 signature 87 104 5.0E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 PRINTS PR00395 Ribosomal protein S2 signature 159 176 5.0E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 PRINTS PR00395 Ribosomal protein S2 signature 197 211 5.0E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 PRINTS PR00395 Ribosomal protein S2 signature 176 187 5.0E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 Pfam PF00318 Ribosomal protein S2 9 225 5.0E-95 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 Gene3D G3DSA:3.40.50.10490 10 215 3.4E-88 T 12-10-2018 AFR_36220 cf14cdfc0ab782de0c843af83542e342 315 Gene3D G3DSA:1.10.287.610 97 153 3.4E-88 T 12-10-2018 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 SUPERFAMILY SSF55874 405 555 2.36E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 SMART SM00387 444 557 6.8E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 Pfam PF00512 His Kinase A (phospho-acceptor) domain 338 400 2.0E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 554 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 498 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 535 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 512 1.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 Gene3D G3DSA:1.10.287.130 293 400 1.3E-11 T 12-10-2018 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 445 555 3.8E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 SUPERFAMILY SSF47384 321 399 7.06E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 Gene3D G3DSA:3.30.565.10 428 558 2.7E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11565 5c2360d885787c01d9ab398a49c0845b 572 SMART SM00388 336 403 3.2E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_03280 750203c60c3ee757af671bd783c30d10 561 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 436 518 2.7E-18 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_03280 750203c60c3ee757af671bd783c30d10 561 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 244 334 6.1E-6 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_03280 750203c60c3ee757af671bd783c30d10 561 SUPERFAMILY SSF53067 4 237 6.76E-45 T 12-10-2018 AFR_03280 750203c60c3ee757af671bd783c30d10 561 SUPERFAMILY SSF53067 436 553 2.27E-22 T 12-10-2018 AFR_03280 750203c60c3ee757af671bd783c30d10 561 Gene3D G3DSA:3.30.420.40 1 227 2.0E-78 T 12-10-2018 AFR_03280 750203c60c3ee757af671bd783c30d10 561 SUPERFAMILY SSF53067 241 332 4.01E-10 T 12-10-2018 AFR_03280 750203c60c3ee757af671bd783c30d10 561 Gene3D G3DSA:3.30.420.40 228 358 2.4E-46 T 12-10-2018 AFR_03280 750203c60c3ee757af671bd783c30d10 561 Gene3D G3DSA:3.30.420.40 431 559 1.5E-40 T 12-10-2018 AFR_03280 750203c60c3ee757af671bd783c30d10 561 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 65 235 6.5E-25 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 SMART SM00478 36 188 1.6E-33 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 ProSitePatterns PS01155 Endonuclease III family signature. 99 128 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 SUPERFAMILY SSF48150 4 216 1.49E-64 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 Gene3D G3DSA:1.10.340.30 17 129 3.5E-68 T 12-10-2018 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 SMART SM00525 189 209 2.6E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 Pfam PF00633 Helix-hairpin-helix motif 96 123 8.2E-8 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 Gene3D G3DSA:1.10.1670.10 7 210 3.5E-68 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 190 206 2.4E-5 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFR_41345 d0700206580ca6b34823f720c61dfc21 300 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 32 161 1.4E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_05975 4c1162c40521cbfed10040208370c6b7 260 Pfam PF01478 Type IV leader peptidase family 106 213 2.9E-11 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFR_05975 4c1162c40521cbfed10040208370c6b7 260 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 12 95 7.5E-35 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal AFR_00340 1237e29c858bc2c0be8272552af40826 350 SMART SM00116 294 341 0.18 T 12-10-2018 IPR000644 CBS domain AFR_00340 1237e29c858bc2c0be8272552af40826 350 SMART SM00116 231 280 0.12 T 12-10-2018 IPR000644 CBS domain AFR_00340 1237e29c858bc2c0be8272552af40826 350 Pfam PF00571 CBS domain 232 278 0.0021 T 12-10-2018 IPR000644 CBS domain AFR_00340 1237e29c858bc2c0be8272552af40826 350 Pfam PF00571 CBS domain 293 341 4.8E-6 T 12-10-2018 IPR000644 CBS domain AFR_00340 1237e29c858bc2c0be8272552af40826 350 Gene3D G3DSA:3.10.580.10 205 345 5.0E-24 T 12-10-2018 AFR_00340 1237e29c858bc2c0be8272552af40826 350 Pfam PF01595 Domain of unknown function DUF21 14 205 3.2E-32 T 12-10-2018 IPR002550 CNNM, transmembrane domain AFR_00340 1237e29c858bc2c0be8272552af40826 350 SUPERFAMILY SSF54631 213 343 3.54E-20 T 12-10-2018 AFR_21815 1147c86d73bdfab4d5bb23ac6c790227 508 Pfam PF07969 Amidohydrolase family 41 505 4.5E-74 T 12-10-2018 IPR013108 Amidohydrolase 3 AFR_21815 1147c86d73bdfab4d5bb23ac6c790227 508 Gene3D G3DSA:3.20.20.140 52 455 7.9E-84 T 12-10-2018 AFR_21815 1147c86d73bdfab4d5bb23ac6c790227 508 SUPERFAMILY SSF51338 4 471 4.32E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_21815 1147c86d73bdfab4d5bb23ac6c790227 508 SUPERFAMILY SSF51556 51 453 3.94E-35 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_21815 1147c86d73bdfab4d5bb23ac6c790227 508 Gene3D G3DSA:2.30.40.10 11 469 7.9E-84 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_21815 1147c86d73bdfab4d5bb23ac6c790227 508 Gene3D G3DSA:3.10.310.70 70 179 7.9E-84 T 12-10-2018 AFR_34990 696b47e90eb59d09a07d55d2d1335814 192 SMART SM00065 38 181 7.8E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_34990 696b47e90eb59d09a07d55d2d1335814 192 Gene3D G3DSA:3.30.450.40 21 185 1.4E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_34990 696b47e90eb59d09a07d55d2d1335814 192 Pfam PF01590 GAF domain 40 170 1.5E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_34990 696b47e90eb59d09a07d55d2d1335814 192 SUPERFAMILY SSF55781 40 176 3.92E-22 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 Gene3D G3DSA:3.50.50.60 6 342 1.1E-103 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 SUPERFAMILY SSF51905 5 358 3.85E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 Gene3D G3DSA:3.40.30.120 363 492 4.6E-12 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 Gene3D G3DSA:3.30.70.2450 186 269 1.1E-103 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 330 346 4.9E-38 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 4.9E-38 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 4.9E-38 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 4.9E-38 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.9E-38 T 12-10-2018 AFR_29370 e729c311ff625b4a28f76d8b3f364bc7 499 Pfam PF01494 FAD binding domain 5 342 2.4E-77 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_09855 3933d3e979cf48afec87d81d917b8767 449 SUPERFAMILY SSF63380 213 311 2.69E-13 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_09855 3933d3e979cf48afec87d81d917b8767 449 Pfam PF01794 Ferric reductase like transmembrane component 53 171 4.1E-16 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain AFR_09855 3933d3e979cf48afec87d81d917b8767 449 SUPERFAMILY SSF52343 303 445 5.37E-25 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_09855 3933d3e979cf48afec87d81d917b8767 449 Pfam PF00175 Oxidoreductase NAD-binding domain 324 429 1.6E-6 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_09855 3933d3e979cf48afec87d81d917b8767 449 PRINTS PR00410 Phenol hydroxylase reductase family signature 307 316 5.9E-5 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_09855 3933d3e979cf48afec87d81d917b8767 449 PRINTS PR00410 Phenol hydroxylase reductase family signature 323 342 5.9E-5 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_09855 3933d3e979cf48afec87d81d917b8767 449 PRINTS PR00410 Phenol hydroxylase reductase family signature 415 423 5.9E-5 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_09855 3933d3e979cf48afec87d81d917b8767 449 Gene3D G3DSA:3.40.50.80 316 449 8.0E-22 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_09855 3933d3e979cf48afec87d81d917b8767 449 Gene3D G3DSA:2.40.30.10 213 311 5.8E-11 T 12-10-2018 AFR_06030 d3c039dc19cd648edd1fbf8afcffd5fb 124 Gene3D G3DSA:3.40.50.12740 2 123 1.4E-33 T 12-10-2018 AFR_06030 d3c039dc19cd648edd1fbf8afcffd5fb 124 SMART SM00448 2 115 4.9E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_06030 d3c039dc19cd648edd1fbf8afcffd5fb 124 SUPERFAMILY SSF52172 4 121 1.42E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_06030 d3c039dc19cd648edd1fbf8afcffd5fb 124 Pfam PF00072 Response regulator receiver domain 4 115 3.6E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13810 200d278814881f0091d9ed550109551e 548 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 2 548 5.6E-209 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFR_13810 200d278814881f0091d9ed550109551e 548 PIRSF PIRSF001294 1 548 4.3E-218 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFR_13810 200d278814881f0091d9ed550109551e 548 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 548 31.948 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFR_13810 200d278814881f0091d9ed550109551e 548 Pfam PF03814 Potassium-transporting ATPase A subunit 9 547 7.3E-232 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFR_12615 be4b42e483dccbde8f67b13fadaa2566 350 Pfam PF00107 Zinc-binding dehydrogenase 182 300 8.0E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_12615 be4b42e483dccbde8f67b13fadaa2566 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 93 1.4E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_12615 be4b42e483dccbde8f67b13fadaa2566 350 SUPERFAMILY SSF50129 12 161 4.11E-33 T 12-10-2018 IPR011032 GroES-like superfamily AFR_12615 be4b42e483dccbde8f67b13fadaa2566 350 Gene3D G3DSA:3.40.50.720 148 293 4.4E-88 T 12-10-2018 AFR_12615 be4b42e483dccbde8f67b13fadaa2566 350 SMART SM00829 18 343 5.0E-15 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_12615 be4b42e483dccbde8f67b13fadaa2566 350 Gene3D G3DSA:3.90.180.10 24 332 4.4E-88 T 12-10-2018 AFR_12615 be4b42e483dccbde8f67b13fadaa2566 350 SUPERFAMILY SSF51735 143 318 1.08E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11685 a412de36d17365a62ff8a301b2644b0c 343 Gene3D G3DSA:3.40.630.30 142 303 1.1E-16 T 12-10-2018 AFR_11685 a412de36d17365a62ff8a301b2644b0c 343 Pfam PF13480 Acetyltransferase (GNAT) domain 156 286 2.4E-11 T 12-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AFR_11685 a412de36d17365a62ff8a301b2644b0c 343 SUPERFAMILY SSF55729 149 322 8.48E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SUPERFAMILY SSF48452 212 416 9.1E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 Gene3D G3DSA:1.25.40.10 320 432 9.1E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 Pfam PF07719 Tetratricopeptide repeat 382 414 2.7E-5 T 12-10-2018 IPR013105 Tetratricopeptide repeat 2 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SMART SM00028 382 415 0.0013 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SMART SM00028 73 106 82.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SMART SM00028 108 141 46.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SMART SM00028 142 175 20.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SMART SM00028 246 279 50.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SMART SM00028 212 245 96.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 Gene3D G3DSA:1.25.40.10 47 311 1.3E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 SUPERFAMILY SSF48452 67 203 1.04E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 Pfam PF13432 Tetratricopeptide repeat 79 138 0.0074 T 12-10-2018 AFR_33420 a4bb09eecc57d9d4108bfc5562e799cf 434 Pfam PF13432 Tetratricopeptide repeat 150 204 0.0074 T 12-10-2018 AFR_22860 7df085f45c8aa90e20241f2c343fbeb3 196 Gene3D G3DSA:1.20.120.1760 5 187 8.8E-12 T 12-10-2018 AFR_22860 7df085f45c8aa90e20241f2c343fbeb3 196 Pfam PF01066 CDP-alcohol phosphatidyltransferase 14 79 6.4E-10 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_22860 7df085f45c8aa90e20241f2c343fbeb3 196 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 57 79 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_34890 d41b0ff352c905c0f02382a94f8050a5 162 Gene3D G3DSA:1.10.10.10 94 162 1.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34890 d41b0ff352c905c0f02382a94f8050a5 162 Pfam PF04545 Sigma-70, region 4 104 152 3.4E-11 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_34890 d41b0ff352c905c0f02382a94f8050a5 162 SUPERFAMILY SSF88659 92 156 2.43E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_34890 d41b0ff352c905c0f02382a94f8050a5 162 SUPERFAMILY SSF88946 2 85 2.67E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34890 d41b0ff352c905c0f02382a94f8050a5 162 Gene3D G3DSA:1.10.1740.10 1 93 7.3E-16 T 12-10-2018 AFR_34890 d41b0ff352c905c0f02382a94f8050a5 162 Pfam PF04542 Sigma-70 region 2 2 69 7.5E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34890 d41b0ff352c905c0f02382a94f8050a5 162 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 155 5.2E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 PIRSF PIRSF036289 1 766 8.5E-219 T 12-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 700 752 8.0E-15 T 12-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 Gene3D G3DSA:2.60.420.10 682 755 7.9E-20 T 12-10-2018 AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 696 4.4E-137 T 12-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 SUPERFAMILY SSF48208 280 749 8.5E-123 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 4.6E-61 T 12-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 Gene3D G3DSA:1.50.10.10 321 681 4.2E-126 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 SUPERFAMILY SSF74650 4 271 2.57E-66 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_02270 3c307d530f84e4338b5ea11e7095b4f1 788 Gene3D G3DSA:2.70.98.40 4 273 6.5E-62 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily AFR_10020 242ca040596b8575a71137cb870d7517 245 Pfam PF08478 POTRA domain, FtsQ-type 56 122 2.0E-15 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type AFR_10020 242ca040596b8575a71137cb870d7517 245 Gene3D G3DSA:3.10.20.310 54 121 2.9E-8 T 12-10-2018 AFR_10020 242ca040596b8575a71137cb870d7517 245 Pfam PF03799 Cell division protein FtsQ 130 235 3.0E-6 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB AFR_28490 84024251e818fcb49798b259f70bf2c9 690 Gene3D G3DSA:2.120.10.30 349 689 6.9E-106 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_28490 84024251e818fcb49798b259f70bf2c9 690 SMART SM00458 35 161 2.0E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_28490 84024251e818fcb49798b259f70bf2c9 690 Pfam PF00652 Ricin-type beta-trefoil lectin domain 37 158 6.2E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_28490 84024251e818fcb49798b259f70bf2c9 690 SUPERFAMILY SSF49265 258 356 1.87E-8 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_28490 84024251e818fcb49798b259f70bf2c9 690 Gene3D G3DSA:2.60.40.10 270 348 5.2E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_28490 84024251e818fcb49798b259f70bf2c9 690 Gene3D G3DSA:2.60.40.10 168 254 8.7E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_28490 84024251e818fcb49798b259f70bf2c9 690 SUPERFAMILY SSF50952 366 670 9.94E-37 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_28490 84024251e818fcb49798b259f70bf2c9 690 Pfam PF07995 Glucose / Sorbosone dehydrogenase 374 668 6.1E-65 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_28490 84024251e818fcb49798b259f70bf2c9 690 SUPERFAMILY SSF49265 165 255 2.49E-5 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_28490 84024251e818fcb49798b259f70bf2c9 690 SMART SM00060 170 244 120.0 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_28490 84024251e818fcb49798b259f70bf2c9 690 SMART SM00060 265 345 0.0025 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_28490 84024251e818fcb49798b259f70bf2c9 690 SUPERFAMILY SSF50370 33 159 7.97E-36 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_28490 84024251e818fcb49798b259f70bf2c9 690 Gene3D G3DSA:2.80.10.50 35 160 4.1E-37 T 12-10-2018 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 SMART SM00387 25 177 3.4E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 162 5.2E-13 T 12-10-2018 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 SUPERFAMILY SSF54211 216 468 2.96E-90 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 Gene3D G3DSA:3.30.230.80 218 385 1.6E-62 T 12-10-2018 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PIRSF PIRSF002583 1 607 1.3E-209 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 Gene3D G3DSA:3.30.565.10 1 217 1.2E-73 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 Pfam PF00183 Hsp90 protein 211 605 6.7E-127 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 605 29.625 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 Gene3D G3DSA:3.40.50.11260 386 473 4.5E-32 T 12-10-2018 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 23 32 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 SUPERFAMILY SSF110942 488 604 1.7E-33 T 12-10-2018 IPR037196 HSP90, C-terminal domain AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 Gene3D G3DSA:1.20.120.790 474 605 1.3E-39 T 12-10-2018 IPR037196 HSP90, C-terminal domain AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PRINTS PR00775 90kDa heat shock protein signature 89 106 5.4E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PRINTS PR00775 90kDa heat shock protein signature 3 23 5.4E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PRINTS PR00775 90kDa heat shock protein signature 115 137 5.4E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PRINTS PR00775 90kDa heat shock protein signature 188 206 5.4E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PRINTS PR00775 90kDa heat shock protein signature 165 182 5.4E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PRINTS PR00775 90kDa heat shock protein signature 24 46 5.4E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 PRINTS PR00775 90kDa heat shock protein signature 71 88 5.4E-57 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_19820 5b9e99dd9b047f8f2d2f8b2627fcb4ac 608 SUPERFAMILY SSF55874 2 213 5.76E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_23315 7c9823e49b35958fafd0da9127163df6 381 Gene3D G3DSA:3.40.50.2000 188 339 8.8E-31 T 12-10-2018 AFR_23315 7c9823e49b35958fafd0da9127163df6 381 Pfam PF00534 Glycosyl transferases group 1 191 339 4.5E-18 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_23315 7c9823e49b35958fafd0da9127163df6 381 Pfam PF13439 Glycosyltransferase Family 4 23 180 7.5E-16 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_23315 7c9823e49b35958fafd0da9127163df6 381 Gene3D G3DSA:3.40.50.2000 1 167 1.7E-19 T 12-10-2018 AFR_23315 7c9823e49b35958fafd0da9127163df6 381 SUPERFAMILY SSF53756 21 359 5.42E-55 T 12-10-2018 AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 SUPERFAMILY SSF46955 6 74 3.2E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 SUPERFAMILY SSF52242 227 288 1.73E-5 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 Pfam PF13411 MerR HTH family regulatory protein 7 70 1.7E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 Pfam PF02607 B12 binding domain 148 215 3.5E-7 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 SMART SM00422 6 75 1.0E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 Gene3D G3DSA:3.40.50.280 225 326 1.7E-14 T 12-10-2018 AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 Gene3D G3DSA:1.10.1240.10 147 220 9.8E-8 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_00875 8bc76a242cc0583ab6268cf131a3b3f5 352 Gene3D G3DSA:1.10.1660.10 2 74 1.2E-19 T 12-10-2018 AFR_05130 e0a9e8b12b6045bf3560827363d9cb3e 269 SMART SM00849 60 259 2.0E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_05130 e0a9e8b12b6045bf3560827363d9cb3e 269 Pfam PF00753 Metallo-beta-lactamase superfamily 62 259 1.4E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_05130 e0a9e8b12b6045bf3560827363d9cb3e 269 Gene3D G3DSA:3.60.15.10 3 267 9.2E-59 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_05130 e0a9e8b12b6045bf3560827363d9cb3e 269 SUPERFAMILY SSF56281 56 264 6.16E-30 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_08215 acab5f858401e2c0fb7c78ece5b9a3d7 347 Gene3D G3DSA:3.40.50.2300 157 342 3.6E-75 T 12-10-2018 AFR_08215 acab5f858401e2c0fb7c78ece5b9a3d7 347 Gene3D G3DSA:3.40.50.2300 55 330 3.6E-75 T 12-10-2018 AFR_08215 acab5f858401e2c0fb7c78ece5b9a3d7 347 SUPERFAMILY SSF53822 52 343 4.04E-53 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_08215 acab5f858401e2c0fb7c78ece5b9a3d7 347 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 3 27 2.2E-5 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFR_08215 acab5f858401e2c0fb7c78ece5b9a3d7 347 Pfam PF13407 Periplasmic binding protein domain 55 311 3.7E-38 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_15430 5cf1ce419385e242b9a4ee944f85f044 225 SMART SM00448 1 112 3.1E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_15430 5cf1ce419385e242b9a4ee944f85f044 225 SMART SM00862 145 220 6.9E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_15430 5cf1ce419385e242b9a4ee944f85f044 225 SUPERFAMILY SSF52172 1 168 8.75E-39 T 12-10-2018 IPR011006 CheY-like superfamily AFR_15430 5cf1ce419385e242b9a4ee944f85f044 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 1.6E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_15430 5cf1ce419385e242b9a4ee944f85f044 225 Gene3D G3DSA:3.40.50.2300 1 121 9.0E-38 T 12-10-2018 AFR_15430 5cf1ce419385e242b9a4ee944f85f044 225 Gene3D G3DSA:1.10.10.10 123 224 3.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15430 5cf1ce419385e242b9a4ee944f85f044 225 Pfam PF00072 Response regulator receiver domain 3 112 1.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 SUPERFAMILY SSF47781 317 388 6.67E-12 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 Gene3D G3DSA:3.40.1700.10 42 177 1.4E-52 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 60 173 1.3E-24 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 Gene3D G3DSA:1.10.150.20 327 390 2.7E-21 T 12-10-2018 AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 Pfam PF12826 Helix-hairpin-helix motif 343 379 1.5E-6 T 12-10-2018 AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 40 391 43.482 T 12-10-2018 IPR023763 DNA integrity scanning protein, DisA AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 SUPERFAMILY SSF143597 53 176 5.1E-28 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 Gene3D G3DSA:1.20.1260.110 178 326 2.5E-45 T 12-10-2018 IPR038331 DisA, linker domain superfamily AFR_41325 8874c16593ad99f8ce1fdab983cc3fc9 394 Pfam PF10635 DisA bacterial checkpoint controller linker region 177 317 5.7E-50 T 12-10-2018 IPR018906 DNA integrity scanning, DisA, linker region AFR_04195 f540c48646acb5175307c2f9fccececf 307 Gene3D G3DSA:3.90.1200.10 149 286 1.5E-6 T 12-10-2018 AFR_04195 f540c48646acb5175307c2f9fccececf 307 Gene3D G3DSA:3.30.200.20 13 97 1.4E-5 T 12-10-2018 AFR_04195 f540c48646acb5175307c2f9fccececf 307 SUPERFAMILY SSF56112 34 257 1.28E-15 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_04195 f540c48646acb5175307c2f9fccececf 307 Pfam PF01636 Phosphotransferase enzyme family 53 235 2.9E-8 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_21300 2ea602e6f446120fbe70508153b834f8 530 SUPERFAMILY SSF52540 343 528 1.89E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21300 2ea602e6f446120fbe70508153b834f8 530 SMART SM00382 26 228 1.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21300 2ea602e6f446120fbe70508153b834f8 530 SMART SM00382 371 528 1.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21300 2ea602e6f446120fbe70508153b834f8 530 Pfam PF00005 ABC transporter 362 480 1.2E-12 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_21300 2ea602e6f446120fbe70508153b834f8 530 Gene3D G3DSA:3.40.50.300 4 281 3.7E-60 T 12-10-2018 AFR_21300 2ea602e6f446120fbe70508153b834f8 530 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_21300 2ea602e6f446120fbe70508153b834f8 530 SUPERFAMILY SSF52540 14 224 6.53E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21300 2ea602e6f446120fbe70508153b834f8 530 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_21300 2ea602e6f446120fbe70508153b834f8 530 Pfam PF00005 ABC transporter 19 183 1.2E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_21300 2ea602e6f446120fbe70508153b834f8 530 Gene3D G3DSA:3.40.50.300 338 530 9.1E-38 T 12-10-2018 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 5 146 1.4E-24 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 Gene3D G3DSA:3.40.50.720 3 130 2.1E-32 T 12-10-2018 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 PIRSF PIRSF036426 1 152 1.8E-32 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 PIRSF PIRSF036426 147 396 2.3E-95 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 Gene3D G3DSA:3.30.950.10 275 397 1.4E-46 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 Pfam PF13241 Putative NAD(P)-binding 6 115 2.1E-21 T 12-10-2018 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 164 178 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 SUPERFAMILY SSF51735 2 106 8.56E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 Gene3D G3DSA:3.40.1010.10 157 274 1.7E-38 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 161 373 8.4E-47 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 SUPERFAMILY SSF53790 155 394 1.96E-74 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_07370 3077643eee45c5a7636a0b59faa36e9c 397 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 159 395 1.1E-84 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFR_25460 50792db68aac792bcac3b686f139d5c0 362 Gene3D G3DSA:3.40.50.2300 41 322 2.8E-73 T 12-10-2018 AFR_25460 50792db68aac792bcac3b686f139d5c0 362 SUPERFAMILY SSF53822 37 333 4.17E-52 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_25460 50792db68aac792bcac3b686f139d5c0 362 Gene3D G3DSA:3.40.50.2300 144 338 2.8E-73 T 12-10-2018 AFR_25460 50792db68aac792bcac3b686f139d5c0 362 Pfam PF13407 Periplasmic binding protein domain 44 300 4.9E-44 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_32545 05aecef07aa7e16d4aae1c87b04fe37d 365 Pfam PF07584 Aerotolerance regulator N-terminal 1 69 9.6E-11 T 12-10-2018 IPR024163 Aerotolerance regulator, N-terminal AFR_32545 05aecef07aa7e16d4aae1c87b04fe37d 365 SUPERFAMILY SSF53300 84 310 3.76E-30 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_32545 05aecef07aa7e16d4aae1c87b04fe37d 365 Pfam PF00092 von Willebrand factor type A domain 88 306 6.7E-18 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_32545 05aecef07aa7e16d4aae1c87b04fe37d 365 Gene3D G3DSA:3.40.50.410 78 313 3.9E-46 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_32545 05aecef07aa7e16d4aae1c87b04fe37d 365 SMART SM00327 85 270 5.6E-13 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 SUPERFAMILY SSF52540 246 450 3.54E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 Hamap MF_00900 GTPase HflX [hflX]. 67 435 50.207 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 Pfam PF01926 50S ribosome-binding GTPase 247 365 6.1E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 Pfam PF13167 GTP-binding GTPase N-terminal 64 152 1.4E-32 T 12-10-2018 IPR025121 GTPase HflX, N-terminal AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 Gene3D G3DSA:3.40.50.11060 57 179 5.8E-42 T 12-10-2018 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 Gene3D G3DSA:3.40.50.300 244 409 1.2E-40 T 12-10-2018 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 247 267 3.4E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 314 332 3.4E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 PIRSF PIRSF006809 12 45 120.0 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 PIRSF PIRSF006809 39 462 1.7E-159 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 48 406 1.0E-136 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFR_35535 f0c878efa4efc3ce49d12717627b7c23 463 Pfam PF16360 GTP-binding GTPase Middle Region 154 239 1.7E-31 T 12-10-2018 IPR032305 GTP-binding protein, middle domain AFR_18560 50bfb2e233fda5374a99b2e937414055 268 Gene3D G3DSA:3.40.50.1820 3 267 2.2E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18560 50bfb2e233fda5374a99b2e937414055 268 PRINTS PR00412 Epoxide hydrolase signature 105 118 7.9E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_18560 50bfb2e233fda5374a99b2e937414055 268 PRINTS PR00412 Epoxide hydrolase signature 241 263 7.9E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_18560 50bfb2e233fda5374a99b2e937414055 268 PRINTS PR00412 Epoxide hydrolase signature 47 62 7.9E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_18560 50bfb2e233fda5374a99b2e937414055 268 SUPERFAMILY SSF53474 2 265 2.98E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18560 50bfb2e233fda5374a99b2e937414055 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 3.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18560 50bfb2e233fda5374a99b2e937414055 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 3.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18560 50bfb2e233fda5374a99b2e937414055 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 3.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18560 50bfb2e233fda5374a99b2e937414055 268 Pfam PF12697 Alpha/beta hydrolase family 22 255 1.6E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 234 355 1.2E-32 T 12-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 Gene3D G3DSA:3.40.50.150 229 404 9.1E-69 T 12-10-2018 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 10 206 6.2E-44 T 12-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 SUPERFAMILY SSF53790 8 209 2.49E-40 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 196 1.2E-20 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 Gene3D G3DSA:3.40.1010.10 6 109 6.0E-17 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 PIRSF PIRSF036428 5 404 7.3E-138 T 12-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 AFR_34005 9605bfea3177ddcd031bf632b8d72c43 404 SUPERFAMILY SSF53335 221 390 7.09E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_31070 f52a18562c58763b953330055aecfbf7 179 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 12-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 AFR_31070 f52a18562c58763b953330055aecfbf7 179 Gene3D G3DSA:3.30.420.10 1 160 1.0E-44 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_31070 f52a18562c58763b953330055aecfbf7 179 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 2.4E-32 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_31070 f52a18562c58763b953330055aecfbf7 179 SUPERFAMILY SSF53098 2 157 9.36E-42 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_31070 f52a18562c58763b953330055aecfbf7 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 2.2E-35 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_31070 f52a18562c58763b953330055aecfbf7 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 2.2E-35 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_31070 f52a18562c58763b953330055aecfbf7 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 2.2E-35 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_31070 f52a18562c58763b953330055aecfbf7 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 2.2E-35 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_31070 f52a18562c58763b953330055aecfbf7 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.2E-35 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_31070 f52a18562c58763b953330055aecfbf7 179 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 41.806 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_31070 f52a18562c58763b953330055aecfbf7 179 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.4E-47 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 SUPERFAMILY SSF48452 94 258 1.14E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 SMART SM00862 17 88 2.7E-4 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 Gene3D G3DSA:1.25.40.10 94 264 4.6E-46 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 Gene3D G3DSA:1.10.10.10 1 89 4.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 Pfam PF00931 NB-ARC domain 274 467 8.3E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 SMART SM01043 95 239 2.5E-44 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 SUPERFAMILY SSF52540 261 484 1.41E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 SUPERFAMILY SSF46894 2 88 5.61E-9 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 Pfam PF03704 Bacterial transcriptional activator domain 95 239 5.7E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 PRINTS PR00364 Disease resistance protein signature 291 306 1.0E-6 T 12-10-2018 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 PRINTS PR00364 Disease resistance protein signature 449 463 1.0E-6 T 12-10-2018 AFR_29450 7efcfee9fa26776c7353f488a59b2384 600 PRINTS PR00364 Disease resistance protein signature 367 381 1.0E-6 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Gene3D G3DSA:3.30.70.870 352 422 2.1E-5 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Pfam PF00009 Elongation factor Tu GTP binding domain 5 242 5.9E-51 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Gene3D G3DSA:3.40.50.300 2 253 1.3E-68 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 507 524 6.0E-27 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 111 134 6.0E-27 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 218 240 6.0E-27 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 458 472 6.0E-27 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 273 299 6.0E-27 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 473 495 6.0E-27 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Gene3D G3DSA:2.40.30.10 254 344 1.6E-5 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Pfam PF03764 Elongation factor G, domain IV 444 534 9.0E-16 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 SUPERFAMILY SSF54980 347 417 5.76E-8 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Pfam PF00679 Elongation factor G C-terminus 538 606 4.5E-9 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 SUPERFAMILY SSF54211 422 535 2.2E-15 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 SUPERFAMILY SSF52540 5 240 1.35E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 SUPERFAMILY SSF50447 228 336 9.89E-9 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Gene3D G3DSA:3.30.70.240 541 605 4.6E-26 T 12-10-2018 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 SMART SM00889 419 535 1.5E-5 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 SUPERFAMILY SSF54980 538 607 4.8E-8 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 141 3.3E-26 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR00315 GTP-binding elongation factor signature 53 61 7.3E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR00315 GTP-binding elongation factor signature 125 134 7.3E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR00315 GTP-binding elongation factor signature 7 20 7.3E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR00315 GTP-binding elongation factor signature 89 100 7.3E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 PRINTS PR00315 GTP-binding elongation factor signature 73 83 7.3E-17 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_24525 6c011180532b77a0f048978d3ef7f29c 650 Gene3D G3DSA:3.30.230.10 445 540 4.6E-26 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_11250 ac500c99a6c8cfc829abc080009faa93 177 SUPERFAMILY SSF55781 37 174 2.18E-24 T 12-10-2018 AFR_11250 ac500c99a6c8cfc829abc080009faa93 177 Pfam PF01590 GAF domain 38 166 1.2E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_11250 ac500c99a6c8cfc829abc080009faa93 177 SMART SM00065 33 172 0.0031 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_11250 ac500c99a6c8cfc829abc080009faa93 177 Gene3D G3DSA:3.30.450.40 25 176 1.8E-18 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_17440 dbea53bcb598bf564104f9865a983a9c 699 SUPERFAMILY SSF63829 349 666 4.84E-7 T 12-10-2018 AFR_17440 dbea53bcb598bf564104f9865a983a9c 699 Pfam PF05787 Bacterial protein of unknown function (DUF839) 104 662 2.6E-158 T 12-10-2018 IPR008557 Protein of unknown function DUF839 AFR_26720 130da9c5dae97e29ea8dc1015a83fb52 415 SMART SM00558 113 256 0.0013 T 12-10-2018 IPR003347 JmjC domain AFR_26720 130da9c5dae97e29ea8dc1015a83fb52 415 Pfam PF08007 Cupin superfamily protein 24 300 2.8E-41 T 12-10-2018 IPR003347 JmjC domain AFR_26720 130da9c5dae97e29ea8dc1015a83fb52 415 Gene3D G3DSA:2.60.120.650 13 246 1.0E-61 T 12-10-2018 AFR_26720 130da9c5dae97e29ea8dc1015a83fb52 415 SUPERFAMILY SSF51197 21 301 1.03E-47 T 12-10-2018 AFR_09215 1d03ffe429003dc54ae80667c4e3bc7f 195 SUPERFAMILY SSF46689 6 79 1.33E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_09215 1d03ffe429003dc54ae80667c4e3bc7f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09215 1d03ffe429003dc54ae80667c4e3bc7f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09215 1d03ffe429003dc54ae80667c4e3bc7f 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 2.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09215 1d03ffe429003dc54ae80667c4e3bc7f 195 Pfam PF13305 WHG domain 92 173 2.8E-13 T 12-10-2018 IPR025996 WHG domain AFR_09215 1d03ffe429003dc54ae80667c4e3bc7f 195 Gene3D G3DSA:1.10.357.10 2 191 6.3E-43 T 12-10-2018 AFR_09215 1d03ffe429003dc54ae80667c4e3bc7f 195 SUPERFAMILY SSF48498 85 188 1.24E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_36750 6d3786d88d05a03d62ee75077db623d6 193 Gene3D G3DSA:3.40.430.10 1 191 1.1E-31 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_36750 6d3786d88d05a03d62ee75077db623d6 193 SUPERFAMILY SSF53597 1 191 7.57E-19 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_36750 6d3786d88d05a03d62ee75077db623d6 193 Pfam PF01872 RibD C-terminal domain 111 170 1.0E-7 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 Gene3D G3DSA:3.20.20.450 498 760 2.5E-87 T 12-10-2018 IPR035919 EAL domain superfamily AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 Pfam PF00990 Diguanylate cyclase, GGDEF domain 322 478 1.5E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 SUPERFAMILY SSF55073 327 486 4.16E-38 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 Gene3D G3DSA:3.30.70.270 317 497 8.5E-49 T 12-10-2018 AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 SMART SM00052 495 743 3.6E-97 T 12-10-2018 IPR001633 EAL domain AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 319 483 3.0E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 Pfam PF00563 EAL domain 501 737 4.8E-65 T 12-10-2018 IPR001633 EAL domain AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 SUPERFAMILY SSF141868 500 750 3.79E-77 T 12-10-2018 IPR035919 EAL domain superfamily AFR_26970 866a9de50ee168a7deebbc44237fc9e9 765 SMART SM00267 309 485 9.4E-49 T 12-10-2018 IPR000160 GGDEF domain AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 502 2.7E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 SUPERFAMILY SSF55874 338 501 3.67E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 482 1.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 457 1.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 1.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 500 1.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 Pfam PF00672 HAMP domain 212 268 1.1E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 SUPERFAMILY SSF47384 269 350 3.73E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 Gene3D G3DSA:3.30.565.10 358 508 4.0E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 SMART SM00387 392 503 5.2E-40 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 Gene3D G3DSA:1.10.287.130 216 349 1.5E-24 T 12-10-2018 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 SMART SM00304 212 274 3.2E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 SMART SM00388 282 349 5.2E-22 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_03940 98e49bf0452059f8c1c51896f2a43c66 514 Pfam PF00512 His Kinase A (phospho-acceptor) domain 284 349 3.0E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 SMART SM00862 11 91 1.4E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 Pfam PF03704 Bacterial transcriptional activator domain 99 236 7.0E-22 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 Gene3D G3DSA:1.25.40.10 96 262 1.1E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 SUPERFAMILY SSF48452 93 244 3.26E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 SUPERFAMILY SSF46894 2 72 2.72E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 SMART SM01043 98 236 9.4E-29 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 Gene3D G3DSA:1.10.10.10 1 94 1.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11955 06e9801edd36d0b5017ad27dc8bd1f41 266 Pfam PF00486 Transcriptional regulatory protein, C terminal 16 71 1.5E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Gene3D G3DSA:2.150.10.10 144 210 2.0E-6 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 102 119 1.1 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 121 136 0.49 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 51 68 0.12 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 138 154 0.1 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 70 86 0.0037 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 166 181 0.38 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 SUPERFAMILY SSF51120 47 184 4.81E-18 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Gene3D G3DSA:2.150.10.10 40 94 8.8E-8 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_08370 8a6536303a14d074cc799c6006627ff6 211 PRINTS PR00313 NodO calcium binding signature 148 156 2.3E-9 T 12-10-2018 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 PRINTS PR00313 NodO calcium binding signature 139 147 2.3E-9 T 12-10-2018 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 PRINTS PR00313 NodO calcium binding signature 76 87 2.3E-9 T 12-10-2018 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 PRINTS PR00313 NodO calcium binding signature 166 175 2.3E-9 T 12-10-2018 AFR_08370 8a6536303a14d074cc799c6006627ff6 211 Gene3D G3DSA:2.150.10.10 95 143 2.7E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_08370 8a6536303a14d074cc799c6006627ff6 211 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 66 84 - T 12-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site AFR_05040 3d21d48c7486d7feeb1f0ecdd62dc9e5 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 313 2.8E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_05040 3d21d48c7486d7feeb1f0ecdd62dc9e5 313 Gene3D G3DSA:1.10.3720.10 96 313 1.9E-24 T 12-10-2018 IPR035906 MetI-like superfamily AFR_05040 3d21d48c7486d7feeb1f0ecdd62dc9e5 313 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 68 2.6E-6 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFR_05040 3d21d48c7486d7feeb1f0ecdd62dc9e5 313 SUPERFAMILY SSF161098 104 295 4.58E-26 T 12-10-2018 IPR035906 MetI-like superfamily AFR_25725 a51f2bdd56f54fa49c48f94402014b4e 262 Pfam PF00005 ABC transporter 43 189 2.4E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_25725 a51f2bdd56f54fa49c48f94402014b4e 262 Gene3D G3DSA:3.40.50.300 23 261 2.2E-64 T 12-10-2018 AFR_25725 a51f2bdd56f54fa49c48f94402014b4e 262 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_25725 a51f2bdd56f54fa49c48f94402014b4e 262 SUPERFAMILY SSF52540 27 242 9.65E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25725 a51f2bdd56f54fa49c48f94402014b4e 262 SMART SM00382 52 238 6.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_12275 e501de278bce80b0b86f4cabefd76970 250 SUPERFAMILY SSF46955 4 101 4.76E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_12275 e501de278bce80b0b86f4cabefd76970 250 Gene3D G3DSA:1.10.1660.10 6 194 9.0E-28 T 12-10-2018 AFR_12275 e501de278bce80b0b86f4cabefd76970 250 Pfam PF13411 MerR HTH family regulatory protein 4 68 1.4E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_12275 e501de278bce80b0b86f4cabefd76970 250 SMART SM00422 3 72 5.6E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_12275 e501de278bce80b0b86f4cabefd76970 250 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 6.0E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_12275 e501de278bce80b0b86f4cabefd76970 250 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 6.0E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_12275 e501de278bce80b0b86f4cabefd76970 250 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 6.0E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_20050 a8047dbf18d81b1d6e0ee30edf7658aa 577 SUPERFAMILY SSF52540 335 575 2.87E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20050 a8047dbf18d81b1d6e0ee30edf7658aa 577 Gene3D G3DSA:1.20.1560.10 7 328 1.0E-50 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20050 a8047dbf18d81b1d6e0ee30edf7658aa 577 Pfam PF00005 ABC transporter 357 505 2.5E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20050 a8047dbf18d81b1d6e0ee30edf7658aa 577 SMART SM00382 366 551 6.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20050 a8047dbf18d81b1d6e0ee30edf7658aa 577 Gene3D G3DSA:3.40.50.300 336 576 3.2E-71 T 12-10-2018 AFR_20050 a8047dbf18d81b1d6e0ee30edf7658aa 577 SUPERFAMILY SSF90123 18 326 9.94E-53 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20050 a8047dbf18d81b1d6e0ee30edf7658aa 577 Pfam PF00664 ABC transporter transmembrane region 28 298 7.9E-29 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_34590 308848b5b2751faf1906485e55d5526f 391 ProSitePatterns PS01053 Arginase family signature. 306 327 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 AFR_34590 308848b5b2751faf1906485e55d5526f 391 PIRSF PIRSF036979 78 382 8.0E-71 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_34590 308848b5b2751faf1906485e55d5526f 391 PRINTS PR00116 Arginase signature 338 352 5.6E-14 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_34590 308848b5b2751faf1906485e55d5526f 391 PRINTS PR00116 Arginase signature 188 203 5.6E-14 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_34590 308848b5b2751faf1906485e55d5526f 391 PRINTS PR00116 Arginase signature 303 332 5.6E-14 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_34590 308848b5b2751faf1906485e55d5526f 391 Gene3D G3DSA:3.40.800.10 66 388 4.0E-92 T 12-10-2018 AFR_34590 308848b5b2751faf1906485e55d5526f 391 SUPERFAMILY SSF52768 69 380 4.14E-86 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily AFR_34590 308848b5b2751faf1906485e55d5526f 391 Pfam PF00491 Arginase family 102 374 1.1E-78 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 SMART SM00421 150 207 1.6E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 Pfam PF00072 Response regulator receiver domain 8 114 4.7E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 SUPERFAMILY SSF46894 143 212 9.52E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 SUPERFAMILY SSF52172 6 137 6.4E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_30315 346c3902895ba16336fae7cda76f0b57 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 204 3.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 7.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 7.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 7.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 SMART SM00448 6 122 1.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30315 346c3902895ba16336fae7cda76f0b57 219 Gene3D G3DSA:3.40.50.12740 6 213 6.8E-58 T 12-10-2018 AFR_13060 9fce5720e4112e50da575d2f76e15f9b 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 4.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13060 9fce5720e4112e50da575d2f76e15f9b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13060 9fce5720e4112e50da575d2f76e15f9b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13060 9fce5720e4112e50da575d2f76e15f9b 205 Gene3D G3DSA:1.10.357.10 3 202 4.0E-30 T 12-10-2018 AFR_13060 9fce5720e4112e50da575d2f76e15f9b 205 SUPERFAMILY SSF46689 9 72 2.57E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 PIRSF PIRSF000429 3 392 2.0E-118 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 SUPERFAMILY SSF53901 269 389 2.38E-36 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 Gene3D G3DSA:3.40.47.10 8 271 1.8E-118 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 Pfam PF02803 Thiolase, C-terminal domain 268 389 7.5E-35 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 SUPERFAMILY SSF53901 7 265 5.01E-56 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 Pfam PF00108 Thiolase, N-terminal domain 8 258 1.1E-55 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 389 3.0E-121 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFR_35200 7799ddfa32b881c6126854d275e1a317 398 Gene3D G3DSA:3.40.47.10 135 383 1.8E-118 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 SUPERFAMILY SSF46894 148 218 4.76E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 Pfam PF00072 Response regulator receiver domain 6 118 7.5E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 8.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 8.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 8.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 SMART SM00421 155 212 1.7E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 SUPERFAMILY SSF52172 4 136 4.98E-31 T 12-10-2018 IPR011006 CheY-like superfamily AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.5E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 SMART SM00448 4 117 8.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21560 2c896dec97df1a421cbae3c71a6400e2 218 Gene3D G3DSA:3.40.50.12740 4 218 3.8E-68 T 12-10-2018 AFR_41805 367495f3b5dd243216666d23d8e60a7f 110 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 5 95 4.5E-27 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_41805 367495f3b5dd243216666d23d8e60a7f 110 Gene3D G3DSA:3.30.1310.10 4 109 2.6E-37 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_41805 367495f3b5dd243216666d23d8e60a7f 110 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 7 101 21.64 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_41805 367495f3b5dd243216666d23d8e60a7f 110 SUPERFAMILY SSF82607 9 101 3.79E-30 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_41805 367495f3b5dd243216666d23d8e60a7f 110 Pfam PF02575 YbaB/EbfC DNA-binding family 13 102 7.8E-35 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_41805 367495f3b5dd243216666d23d8e60a7f 110 PIRSF PIRSF004555 5 110 5.0E-35 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 SUPERFAMILY SSF52518 399 607 7.68E-69 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 36 200 6.6E-57 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 458 477 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 574 8.3E-50 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 SUPERFAMILY SSF52467 217 389 9.05E-63 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 Gene3D G3DSA:3.40.50.970 393 606 6.5E-72 T 12-10-2018 AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 Gene3D G3DSA:3.40.50.970 28 205 1.1E-69 T 12-10-2018 AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 Gene3D G3DSA:3.40.50.1220 219 387 4.7E-64 T 12-10-2018 AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 36 596 2.5E-234 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 SUPERFAMILY SSF52518 31 214 5.5E-61 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_36895 f4109889104ab08c69e6825d9ffd61a8 610 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 224 359 4.5E-49 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 4 142 1.4E-63 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 SUPERFAMILY SSF46955 4 126 1.03E-30 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 Pfam PF09278 MerR, DNA binding 46 111 3.6E-18 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 SMART SM00422 4 72 2.3E-26 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 6.0E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 6.0E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 6.0E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 Gene3D G3DSA:1.10.1660.10 1 127 1.1E-36 T 12-10-2018 AFR_42330 4d967cabdefbbc4a5e4afaab76480cf9 146 Pfam PF00376 MerR family regulatory protein 5 41 1.3E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_12935 79e528b8e9eaddc38d9bed438866cfcf 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 177 3.5E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_12935 79e528b8e9eaddc38d9bed438866cfcf 184 Gene3D G3DSA:1.10.10.10 113 183 2.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12935 79e528b8e9eaddc38d9bed438866cfcf 184 Pfam PF04542 Sigma-70 region 2 27 93 2.5E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_12935 79e528b8e9eaddc38d9bed438866cfcf 184 Pfam PF04545 Sigma-70, region 4 127 176 4.0E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_12935 79e528b8e9eaddc38d9bed438866cfcf 184 Gene3D G3DSA:1.10.1740.10 10 91 9.7E-16 T 12-10-2018 AFR_12935 79e528b8e9eaddc38d9bed438866cfcf 184 SUPERFAMILY SSF88946 20 109 1.92E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_12935 79e528b8e9eaddc38d9bed438866cfcf 184 SUPERFAMILY SSF88659 105 180 1.38E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_28910 e239157bb859b9e0aa1e4dde16f72ad8 196 Gene3D G3DSA:1.10.357.10 73 194 2.9E-31 T 12-10-2018 AFR_28910 e239157bb859b9e0aa1e4dde16f72ad8 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 2.8E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28910 e239157bb859b9e0aa1e4dde16f72ad8 196 Gene3D G3DSA:1.10.10.60 1 67 1.1E-27 T 12-10-2018 AFR_28910 e239157bb859b9e0aa1e4dde16f72ad8 196 SUPERFAMILY SSF48498 81 192 3.89E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_28910 e239157bb859b9e0aa1e4dde16f72ad8 196 SUPERFAMILY SSF46689 2 66 7.7E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_28910 e239157bb859b9e0aa1e4dde16f72ad8 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28910 e239157bb859b9e0aa1e4dde16f72ad8 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_07420 19bb95081b059b60370a29d648d7931f 451 Pfam PF07690 Major Facilitator Superfamily 36 349 2.2E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_07420 19bb95081b059b60370a29d648d7931f 451 SUPERFAMILY SSF103473 31 417 1.57E-34 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_07420 19bb95081b059b60370a29d648d7931f 451 Gene3D G3DSA:1.20.1250.20 28 413 5.5E-29 T 12-10-2018 AFR_03525 c978f0d4fe4fd94a4325db371eefa545 322 Gene3D G3DSA:3.40.50.720 123 290 1.2E-69 T 12-10-2018 AFR_03525 c978f0d4fe4fd94a4325db371eefa545 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 85 4.2E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_03525 c978f0d4fe4fd94a4325db371eefa545 322 SUPERFAMILY SSF50129 1 148 3.8E-33 T 12-10-2018 IPR011032 GroES-like superfamily AFR_03525 c978f0d4fe4fd94a4325db371eefa545 322 Gene3D G3DSA:3.90.180.10 8 317 1.2E-69 T 12-10-2018 AFR_03525 c978f0d4fe4fd94a4325db371eefa545 322 Pfam PF13602 Zinc-binding dehydrogenase 186 320 3.5E-15 T 12-10-2018 AFR_03525 c978f0d4fe4fd94a4325db371eefa545 322 SMART SM00829 10 320 1.9E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_03525 c978f0d4fe4fd94a4325db371eefa545 322 SUPERFAMILY SSF51735 115 264 2.06E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 SUPERFAMILY SSF51735 4 181 5.64E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 182 1.0E-66 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 SUPERFAMILY SSF48179 186 282 5.7E-29 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 PIRSF PIRSF000105 1 282 1.3E-89 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 1.2E-30 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 12-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 Gene3D G3DSA:3.40.50.720 2 182 2.3E-67 T 12-10-2018 AFR_37295 cf78c4959527593f0c8543366bb36c5c 282 Gene3D G3DSA:1.10.1040.10 188 282 1.3E-32 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_16835 5e00f760f8fb7beb51fd3f0a30715a80 275 SUPERFAMILY SSF51658 14 248 1.8E-37 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_16835 5e00f760f8fb7beb51fd3f0a30715a80 275 Pfam PF01261 Xylose isomerase-like TIM barrel 21 216 3.6E-26 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_16835 5e00f760f8fb7beb51fd3f0a30715a80 275 Gene3D G3DSA:3.20.20.150 6 248 3.2E-49 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 SMART SM00929 94 134 1.5E-17 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Gene3D G3DSA:2.40.40.20 707 810 5.2E-7 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Gene3D G3DSA:3.30.70.20 137 234 3.0E-5 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 109 121 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Gene3D G3DSA:3.10.20.740 10 133 7.9E-35 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 96 129 1.1E-15 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Pfam PF00384 Molybdopterin oxidoreductase 303 446 4.9E-14 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01685 a31b5bd97180737d21d3884343b24574 824 SUPERFAMILY SSF54862 87 242 1.67E-27 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Gene3D G3DSA:2.20.25.90 248 299 3.1E-9 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Gene3D G3DSA:3.40.50.740 512 694 5.1E-26 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 SUPERFAMILY SSF50692 714 791 2.66E-12 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFR_01685 a31b5bd97180737d21d3884343b24574 824 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 9 84 1.9E-18 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 SUPERFAMILY SSF54292 10 83 2.0E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Gene3D G3DSA:3.40.50.740 305 493 1.6E-13 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 SUPERFAMILY SSF53706 237 690 3.59E-77 T 12-10-2018 AFR_01685 a31b5bd97180737d21d3884343b24574 824 Pfam PF01568 Molydopterin dinucleotide binding domain 737 792 1.9E-8 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFR_01685 a31b5bd97180737d21d3884343b24574 824 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 13 656 2.5E-158 T 12-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01685 a31b5bd97180737d21d3884343b24574 824 SMART SM00926 246 300 1.9E-5 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01685 a31b5bd97180737d21d3884343b24574 824 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 40 57 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01685 a31b5bd97180737d21d3884343b24574 824 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 157 167 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_42245 e359f28d0021424f8ce13156ceb8b026 251 PIRSF PIRSF014899 1 251 5.9E-93 T 12-10-2018 IPR012664 Conserved hypothetical protein CHP02452 AFR_42245 e359f28d0021424f8ce13156ceb8b026 251 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 5 143 8.9E-48 T 12-10-2018 IPR019261 Domain of unknown function DUF2263 AFR_42245 e359f28d0021424f8ce13156ceb8b026 251 SUPERFAMILY SSF52949 180 243 5.18E-6 T 12-10-2018 AFR_42245 e359f28d0021424f8ce13156ceb8b026 251 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 3 247 4.7E-81 T 12-10-2018 IPR012664 Conserved hypothetical protein CHP02452 AFR_42245 e359f28d0021424f8ce13156ceb8b026 251 Gene3D G3DSA:3.40.220.10 1 251 2.0E-79 T 12-10-2018 AFR_06445 125606dcc7b3c4e8d9261bd9752cd3b8 172 Gene3D G3DSA:3.40.630.30 8 171 8.2E-28 T 12-10-2018 AFR_06445 125606dcc7b3c4e8d9261bd9752cd3b8 172 SUPERFAMILY SSF55729 17 171 5.49E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_06445 125606dcc7b3c4e8d9261bd9752cd3b8 172 Pfam PF13673 Acetyltransferase (GNAT) domain 59 149 6.6E-7 T 12-10-2018 IPR000182 GNAT domain AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 SUPERFAMILY SSF51905 1 204 1.96E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 45 63 1.4E-11 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 128 144 1.4E-11 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 1 13 1.4E-11 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 187 202 1.4E-11 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 Pfam PF00743 Flavin-binding monooxygenase-like 2 232 4.5E-31 T 12-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 SUPERFAMILY SSF51905 295 496 1.0E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 PIRSF PIRSF000332 1 239 1.4E-34 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_23685 c858f9851a0b7bbeb8be5fdd0ae2be0e 507 PIRSF PIRSF000332 300 503 2.5E-4 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SUPERFAMILY SSF51126 194 531 1.4E-29 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 Gene3D G3DSA:2.60.120.260 768 905 3.3E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 Gene3D G3DSA:2.60.120.260 621 755 3.5E-29 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 Gene3D G3DSA:2.60.120.260 37 186 1.6E-8 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 Pfam PF12708 Pectate lyase superfamily protein 201 414 7.4E-17 T 12-10-2018 IPR024535 Pectate lyase superfamily protein AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SMART SM00231 767 905 0.0057 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SMART SM00231 620 752 0.082 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SMART SM00710 366 388 1400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SMART SM00710 319 340 5100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SMART SM00710 342 363 6000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SMART SM00710 417 441 450.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SMART SM00710 516 538 530.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 Gene3D G3DSA:2.160.20.10 202 580 2.5E-32 T 12-10-2018 IPR012334 Pectin lyase fold AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SUPERFAMILY SSF49785 622 751 2.69E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 Pfam PF00754 F5/8 type C domain 776 900 6.5E-18 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 Pfam PF00754 F5/8 type C domain 629 746 4.4E-15 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33145 155e0ccfa7beb70b242097fcf943cce2 905 SUPERFAMILY SSF49785 759 903 1.84E-24 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_34050 03af07316d57a49c3ce078518c938e0b 388 SUPERFAMILY SSF49742 280 379 9.94E-12 T 12-10-2018 IPR008977 PHM/PNGase F domain superfamily GO:0003824 AFR_34050 03af07316d57a49c3ce078518c938e0b 388 SUPERFAMILY SSF49742 43 205 1.67E-24 T 12-10-2018 IPR008977 PHM/PNGase F domain superfamily GO:0003824 AFR_34050 03af07316d57a49c3ce078518c938e0b 388 Gene3D G3DSA:2.60.120.310 36 208 6.6E-11 T 12-10-2018 IPR036939 Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily GO:0004497|GO:0005507|GO:0016715|GO:0055114 AFR_34050 03af07316d57a49c3ce078518c938e0b 388 Gene3D G3DSA:2.60.120.230 265 388 2.9E-7 T 12-10-2018 IPR014784 Copper type II, ascorbate-dependent monooxygenase-like, C-terminal GO:0016715|GO:0055114 AFR_34050 03af07316d57a49c3ce078518c938e0b 388 Pfam PF03712 Copper type II ascorbate-dependent monooxygenase, C-terminal domain 281 378 4.6E-5 T 12-10-2018 IPR024548 Copper type II ascorbate-dependent monooxygenase, C-terminal AFR_31745 7b3c3ae3b6d3d93242f362e019a1aa71 339 SUPERFAMILY SSF50952 27 322 1.27E-50 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_31745 7b3c3ae3b6d3d93242f362e019a1aa71 339 Gene3D G3DSA:2.120.10.30 3 337 3.7E-122 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_31745 7b3c3ae3b6d3d93242f362e019a1aa71 339 Pfam PF07995 Glucose / Sorbosone dehydrogenase 34 322 2.7E-75 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_16595 36f8110a17a7f16f31f67d405a10778d 397 Gene3D G3DSA:3.40.50.2000 1 379 1.9E-119 T 12-10-2018 AFR_16595 36f8110a17a7f16f31f67d405a10778d 397 Gene3D G3DSA:3.40.50.2000 189 362 1.9E-119 T 12-10-2018 AFR_16595 36f8110a17a7f16f31f67d405a10778d 397 SUPERFAMILY SSF53756 16 382 7.22E-90 T 12-10-2018 AFR_16595 36f8110a17a7f16f31f67d405a10778d 397 Pfam PF00534 Glycosyl transferases group 1 205 356 3.8E-35 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_16595 36f8110a17a7f16f31f67d405a10778d 397 Pfam PF13439 Glycosyltransferase Family 4 17 193 1.9E-33 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_25700 0c76b70269b3d5a37dc49288c5f2bab5 714 Gene3D G3DSA:2.60.40.10 420 510 4.2E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_25700 0c76b70269b3d5a37dc49288c5f2bab5 714 SUPERFAMILY SSF55846 222 408 2.45E-40 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_25700 0c76b70269b3d5a37dc49288c5f2bab5 714 SMART SM00701 222 370 7.9E-34 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_25700 0c76b70269b3d5a37dc49288c5f2bab5 714 Gene3D G3DSA:3.40.80.10 212 414 1.6E-49 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_25700 0c76b70269b3d5a37dc49288c5f2bab5 714 Gene3D G3DSA:2.60.120.260 601 711 5.6E-8 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25700 0c76b70269b3d5a37dc49288c5f2bab5 714 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 244 397 4.4E-12 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_17165 68b570438168c380ae7a64833fe7a9dd 216 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 27 179 1.7E-9 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 AFR_17165 68b570438168c380ae7a64833fe7a9dd 216 SUPERFAMILY SSF52540 23 208 5.01E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_17165 68b570438168c380ae7a64833fe7a9dd 216 Gene3D G3DSA:3.40.50.300 53 215 2.8E-41 T 12-10-2018 AFR_17165 68b570438168c380ae7a64833fe7a9dd 216 Gene3D G3DSA:3.40.50.300 7 52 6.7E-7 T 12-10-2018 AFR_25025 e3427552088fc144450e9ceba2917879 289 Gene3D G3DSA:3.40.50.720 11 264 2.2E-89 T 12-10-2018 AFR_25025 e3427552088fc144450e9ceba2917879 289 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 10 124 1.3E-31 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 SUPERFAMILY SSF51735 126 286 4.2E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_25025 e3427552088fc144450e9ceba2917879 289 Hamap MF_01576 Bifunctional protein FolD [folD]. 7 288 31.768 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 SUPERFAMILY SSF53223 7 125 2.21E-32 T 12-10-2018 AFR_25025 e3427552088fc144450e9ceba2917879 289 Gene3D G3DSA:3.40.50.10860 12 281 2.2E-89 T 12-10-2018 AFR_25025 e3427552088fc144450e9ceba2917879 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 78 105 3.6E-58 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 158 178 3.6E-58 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 37 59 3.6E-58 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 113 134 3.6E-58 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 261 279 3.6E-58 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 211 240 3.6E-58 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_25025 e3427552088fc144450e9ceba2917879 289 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 127 286 7.6E-48 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFR_24565 67edd3396d0a2515bb5e3cff5619d2b9 687 SUPERFAMILY SSF63829 337 654 6.54E-8 T 12-10-2018 AFR_24565 67edd3396d0a2515bb5e3cff5619d2b9 687 Pfam PF05787 Bacterial protein of unknown function (DUF839) 91 650 3.3E-163 T 12-10-2018 IPR008557 Protein of unknown function DUF839 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 Pfam PF01433 Peptidase family M1 domain 236 448 8.6E-59 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 265 275 2.5E-20 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 331 2.5E-20 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 138 153 2.5E-20 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 186 201 2.5E-20 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 300 315 2.5E-20 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 SUPERFAMILY SSF55486 210 457 4.54E-68 T 12-10-2018 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 SUPERFAMILY SSF63737 6 203 2.62E-37 T 12-10-2018 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 6 846 5.7E-292 T 12-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 Gene3D G3DSA:1.10.390.60 208 465 2.6E-70 T 12-10-2018 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 Gene3D G3DSA:2.60.40.1730 16 204 2.6E-27 T 12-10-2018 AFR_07465 68512d67d32a38db413d91f2c879eb18 852 Pfam PF11838 ERAP1-like C-terminal domain 531 838 5.6E-51 T 12-10-2018 IPR024571 ERAP1-like C-terminal domain AFR_25205 b792dc204499e79de7950f38c8aa7a68 333 SUPERFAMILY SSF75005 28 331 2.88E-62 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_25205 b792dc204499e79de7950f38c8aa7a68 333 Gene3D G3DSA:2.115.10.20 23 331 1.2E-89 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_25205 b792dc204499e79de7950f38c8aa7a68 333 PIRSF PIRSF025414 4 332 3.0E-132 T 12-10-2018 IPR016828 Alpha-L-arabinofuranosidase KEGG: 00520+3.2.1.55 AFR_25205 b792dc204499e79de7950f38c8aa7a68 333 Pfam PF04616 Glycosyl hydrolases family 43 28 325 1.1E-60 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_27480 90a6692f95be33f77e1577ee3140fc2e 378 Gene3D G3DSA:2.60.40.10 177 267 6.6E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27480 90a6692f95be33f77e1577ee3140fc2e 378 Gene3D G3DSA:2.60.40.10 280 367 6.0E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27480 90a6692f95be33f77e1577ee3140fc2e 378 SUPERFAMILY SSF49265 178 366 1.48E-8 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_27480 90a6692f95be33f77e1577ee3140fc2e 378 Gene3D G3DSA:2.60.120.560 3 168 1.3E-28 T 12-10-2018 AFR_27480 90a6692f95be33f77e1577ee3140fc2e 378 SMART SM00060 283 360 11.0 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_27480 90a6692f95be33f77e1577ee3140fc2e 378 SMART SM00060 179 258 0.0023 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_25280 9bf92679c6dc19897ce9275aaed215fb 443 Gene3D G3DSA:3.40.190.10 164 434 1.6E-108 T 12-10-2018 AFR_25280 9bf92679c6dc19897ce9275aaed215fb 443 SUPERFAMILY SSF53850 39 441 2.38E-56 T 12-10-2018 AFR_25280 9bf92679c6dc19897ce9275aaed215fb 443 Pfam PF01547 Bacterial extracellular solute-binding protein 65 347 5.8E-22 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_25280 9bf92679c6dc19897ce9275aaed215fb 443 Gene3D G3DSA:3.40.190.10 54 387 1.6E-108 T 12-10-2018 AFR_37100 fc1b9261c5d05a6cd4d2970c691bf510 485 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 31 323 2.1E-71 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_37100 fc1b9261c5d05a6cd4d2970c691bf510 485 PRINTS PR00133 Glycosyl hydrolase family 3 signature 242 260 7.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_37100 fc1b9261c5d05a6cd4d2970c691bf510 485 PRINTS PR00133 Glycosyl hydrolase family 3 signature 88 107 7.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_37100 fc1b9261c5d05a6cd4d2970c691bf510 485 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 7.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_37100 fc1b9261c5d05a6cd4d2970c691bf510 485 Gene3D G3DSA:3.20.20.300 11 342 7.5E-99 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_37100 fc1b9261c5d05a6cd4d2970c691bf510 485 SUPERFAMILY SSF51445 16 328 1.79E-75 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_13570 88914fb813c81d148785574bd31cd998 265 Pfam PF00571 CBS domain 6 60 2.8E-9 T 12-10-2018 IPR000644 CBS domain AFR_13570 88914fb813c81d148785574bd31cd998 265 Pfam PF00571 CBS domain 90 140 1.8E-11 T 12-10-2018 IPR000644 CBS domain AFR_13570 88914fb813c81d148785574bd31cd998 265 Pfam PF04972 BON domain 146 210 2.1E-9 T 12-10-2018 IPR007055 BON domain AFR_13570 88914fb813c81d148785574bd31cd998 265 Gene3D G3DSA:3.10.580.10 2 155 2.2E-30 T 12-10-2018 AFR_13570 88914fb813c81d148785574bd31cd998 265 SMART SM00116 95 143 8.2E-9 T 12-10-2018 IPR000644 CBS domain AFR_13570 88914fb813c81d148785574bd31cd998 265 SMART SM00116 13 61 1.1E-5 T 12-10-2018 IPR000644 CBS domain AFR_13570 88914fb813c81d148785574bd31cd998 265 SUPERFAMILY SSF54631 4 140 2.27E-29 T 12-10-2018 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 Gene3D G3DSA:3.40.50.720 4 165 4.2E-56 T 12-10-2018 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 SUPERFAMILY SSF51735 7 166 3.79E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 7 293 3.5E-112 T 12-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 SUPERFAMILY SSF48179 166 293 3.4E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 PIRSF PIRSF000103 2 297 6.0E-77 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 285 8.8E-34 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 165 3.8E-50 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 Gene3D G3DSA:1.10.1040.10 166 295 4.6E-36 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_26145 107062a879c3dcc77b0a688adcc9b5a9 297 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFR_05410 8df1ca83c16deb614f1b8a6cf58c9412 413 SUPERFAMILY SSF53901 291 412 4.61E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_05410 8df1ca83c16deb614f1b8a6cf58c9412 413 Pfam PF02803 Thiolase, C-terminal domain 290 412 5.4E-47 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFR_05410 8df1ca83c16deb614f1b8a6cf58c9412 413 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 411 2.4E-133 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_05410 8df1ca83c16deb614f1b8a6cf58c9412 413 ProSitePatterns PS00737 Thiolases signature 2. 359 375 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFR_05410 8df1ca83c16deb614f1b8a6cf58c9412 413 SUPERFAMILY SSF53901 3 290 4.51E-66 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_05410 8df1ca83c16deb614f1b8a6cf58c9412 413 Pfam PF00108 Thiolase, N-terminal domain 5 282 4.1E-61 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFR_05410 8df1ca83c16deb614f1b8a6cf58c9412 413 PIRSF PIRSF000429 1 413 2.0E-125 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 182 192 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 Pfam PF00082 Subtilase family 148 374 3.9E-35 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 146 157 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 Gene3D G3DSA:3.40.50.200 112 393 1.2E-83 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 Gene3D G3DSA:3.30.70.80 35 102 1.3E-17 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 SUPERFAMILY SSF54897 40 108 3.68E-11 T 12-10-2018 AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 337 347 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 Pfam PF05922 Peptidase inhibitor I9 43 107 6.5E-8 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 PRINTS PR00723 Subtilisin serine protease family (S8) signature 141 160 3.2E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 PRINTS PR00723 Subtilisin serine protease family (S8) signature 336 352 3.2E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 PRINTS PR00723 Subtilisin serine protease family (S8) signature 178 191 3.2E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34540 d40ff86e8aaed8783b8a6f0828b4310a 394 SUPERFAMILY SSF52743 116 386 1.44E-70 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_29640 12426a7173fa91c4917f98d051b8f885 695 Pfam PF02616 Segregation and condensation protein ScpA 37 259 3.2E-49 T 12-10-2018 IPR003768 Segregation and condensation protein A AFR_34960 abb37e844c755755fb947f5907f70d9a 378 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFR_34960 abb37e844c755755fb947f5907f70d9a 378 Pfam PF00155 Aminotransferase class I and II 33 373 8.0E-60 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_34960 abb37e844c755755fb947f5907f70d9a 378 SUPERFAMILY SSF53383 28 376 6.86E-94 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_34960 abb37e844c755755fb947f5907f70d9a 378 Gene3D G3DSA:3.90.1150.10 35 365 2.5E-111 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_34960 abb37e844c755755fb947f5907f70d9a 378 Gene3D G3DSA:3.40.640.10 49 279 2.5E-111 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_14155 3083a46a4fbb855e049271bcb3e3de15 231 SUPERFAMILY SSF53474 6 222 7.25E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14155 3083a46a4fbb855e049271bcb3e3de15 231 Gene3D G3DSA:3.40.50.1820 2 227 8.1E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14155 3083a46a4fbb855e049271bcb3e3de15 231 Pfam PF12697 Alpha/beta hydrolase family 7 218 7.0E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 Gene3D G3DSA:3.50.50.60 3 233 5.3E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.5E-5 T 12-10-2018 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 332 339 3.5E-5 T 12-10-2018 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 181 3.5E-5 T 12-10-2018 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 SUPERFAMILY SSF46977 400 513 3.27E-16 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 Gene3D G3DSA:1.20.58.100 390 485 1.1E-7 T 12-10-2018 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 SUPERFAMILY SSF51905 5 372 7.13E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 Pfam PF00890 FAD binding domain 103 210 2.1E-12 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 Pfam PF00890 FAD binding domain 10 66 3.8E-6 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 198 216 1.2E-8 T 12-10-2018 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 317 339 1.2E-8 T 12-10-2018 AFR_22335 a598806ef071f099bc4ea316a3ade24b 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.2E-8 T 12-10-2018 AFR_19740 8049d4a032e20d0cb409fea7318637ec 132 Gene3D G3DSA:3.30.479.10 1 132 1.9E-24 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 AFR_19740 8049d4a032e20d0cb409fea7318637ec 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 2.3E-19 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AFR_19740 8049d4a032e20d0cb409fea7318637ec 132 SUPERFAMILY SSF55620 1 129 1.33E-25 T 12-10-2018 AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 PIRSF PIRSF001549 1 442 3.4E-91 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 424 7.7E-100 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 SUPERFAMILY SSF55681 5 338 1.15E-62 T 12-10-2018 AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 Pfam PF03129 Anticodon binding domain 350 408 7.9E-7 T 12-10-2018 IPR004154 Anticodon-binding AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 SUPERFAMILY SSF52954 347 427 2.11E-12 T 12-10-2018 AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 Pfam PF13393 Histidyl-tRNA synthetase 9 329 5.9E-23 T 12-10-2018 AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 Gene3D G3DSA:3.30.930.10 1 341 1.2E-81 T 12-10-2018 AFR_31015 110999d01f3ffefe3ee159eba74b11b4 443 Gene3D G3DSA:3.40.50.800 345 430 3.4E-13 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 Gene3D G3DSA:3.40.50.2300 1 113 5.3E-35 T 12-10-2018 AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 Pfam PF00072 Response regulator receiver domain 1 110 4.2E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 2.9E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 SMART SM00862 145 221 1.5E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 SUPERFAMILY SSF52172 1 120 4.84E-40 T 12-10-2018 IPR011006 CheY-like superfamily AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 SUPERFAMILY SSF46894 120 221 1.22E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 SMART SM00448 1 109 1.1E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_27670 3c436f56c9f6d8c5675cd11baf4275b1 223 Gene3D G3DSA:1.10.10.10 114 223 3.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29965 2038f34cf483225b1d19720431b0cb12 296 Pfam PF00005 ABC transporter 21 155 2.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_29965 2038f34cf483225b1d19720431b0cb12 296 Gene3D G3DSA:3.40.50.300 2 224 2.4E-53 T 12-10-2018 AFR_29965 2038f34cf483225b1d19720431b0cb12 296 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_29965 2038f34cf483225b1d19720431b0cb12 296 SUPERFAMILY SSF52540 4 217 5.73E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29965 2038f34cf483225b1d19720431b0cb12 296 SMART SM00382 29 202 5.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10005 0a9b9eeec9bb4be03771b6aafb7e028a 484 Pfam PF01098 Cell cycle protein 53 426 3.4E-79 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10005 0a9b9eeec9bb4be03771b6aafb7e028a 484 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 386 410 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 SMART SM00304 216 268 6.2E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 SMART SM00304 475 527 76.0 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 66 81 1.1E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 293 322 1.1E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 374 401 1.1E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 403 432 1.1E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 451 480 1.1E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 10 35 1.1E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 Pfam PF12729 Four helix bundle sensory module for signal transduction 10 182 3.5E-14 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 335 497 4.3E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 SMART SM00283 276 530 2.3E-51 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 SUPERFAMILY SSF58104 236 529 2.22E-63 T 12-10-2018 AFR_18210 a949087c6efb8b793c0c68948f9a5445 531 Gene3D G3DSA:1.10.287.950 215 531 4.4E-64 T 12-10-2018 AFR_29080 1b837bcfa6cf70fdba40acee60138a41 283 SUPERFAMILY SSF53613 2 277 2.49E-66 T 12-10-2018 IPR029056 Ribokinase-like AFR_29080 1b837bcfa6cf70fdba40acee60138a41 283 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 2 282 8.3E-96 T 12-10-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFR_29080 1b837bcfa6cf70fdba40acee60138a41 283 Pfam PF08543 Phosphomethylpyrimidine kinase 91 257 5.0E-15 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFR_29080 1b837bcfa6cf70fdba40acee60138a41 283 Gene3D G3DSA:3.40.1190.20 1 283 1.8E-81 T 12-10-2018 IPR029056 Ribokinase-like AFR_15390 548979ebb1a8aab0780c22c89cf2272b 491 SMART SM00267 322 490 3.2E-55 T 12-10-2018 IPR000160 GGDEF domain AFR_15390 548979ebb1a8aab0780c22c89cf2272b 491 Gene3D G3DSA:3.30.70.270 326 491 5.5E-52 T 12-10-2018 AFR_15390 548979ebb1a8aab0780c22c89cf2272b 491 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 330 486 2.7E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_15390 548979ebb1a8aab0780c22c89cf2272b 491 Pfam PF00990 Diguanylate cyclase, GGDEF domain 332 486 4.3E-45 T 12-10-2018 IPR000160 GGDEF domain AFR_15390 548979ebb1a8aab0780c22c89cf2272b 491 SUPERFAMILY SSF55073 337 486 1.18E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.5E-79 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.9E-46 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 SMART SM01003 4 137 2.3E-77 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 SUPERFAMILY SSF52283 1 360 5.44E-66 T 12-10-2018 AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 369 1.0E-167 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 Gene3D G3DSA:3.40.50.720 130 305 3.0E-136 T 12-10-2018 AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 Gene3D G3DSA:3.40.50.720 3 351 3.0E-136 T 12-10-2018 AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 SMART SM01002 149 297 2.2E-79 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 PIRSF PIRSF000183 1 371 6.9E-165 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 12-10-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 AFR_29880 bfde561c2e78f04f7b00c571f554742b 371 SUPERFAMILY SSF51735 137 303 6.81E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 Gene3D G3DSA:1.10.10.10 1 134 6.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 SUPERFAMILY SSF46785 7 133 1.27E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 SMART SM00347 21 121 2.9E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 Pfam PF01047 MarR family 32 86 2.3E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09820 c5c5418c73c7f43727ba7b24bc65f954 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_24295 5668c245b0bb530b3fb7a3e838afa18e 141 Pfam PF13466 STAS domain 31 111 1.9E-14 T 12-10-2018 IPR002645 STAS domain AFR_24295 5668c245b0bb530b3fb7a3e838afa18e 141 SUPERFAMILY SSF52091 26 116 2.55E-17 T 12-10-2018 IPR036513 STAS domain superfamily AFR_24295 5668c245b0bb530b3fb7a3e838afa18e 141 Gene3D G3DSA:3.30.750.24 21 117 6.0E-20 T 12-10-2018 IPR036513 STAS domain superfamily AFR_18110 8442b57ec6ad818ed72a487aea01d489 602 Gene3D G3DSA:3.30.200.20 9 95 3.7E-16 T 12-10-2018 AFR_18110 8442b57ec6ad818ed72a487aea01d489 602 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 45 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_18110 8442b57ec6ad818ed72a487aea01d489 602 SUPERFAMILY SSF56112 13 304 3.06E-63 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_18110 8442b57ec6ad818ed72a487aea01d489 602 Gene3D G3DSA:1.10.510.10 96 274 1.1E-41 T 12-10-2018 AFR_18110 8442b57ec6ad818ed72a487aea01d489 602 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_18110 8442b57ec6ad818ed72a487aea01d489 602 SMART SM00220 17 271 7.3E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_18110 8442b57ec6ad818ed72a487aea01d489 602 Pfam PF00069 Protein kinase domain 17 266 1.6E-39 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 Pfam PF16499 Alpha galactosidase A 32 316 3.6E-79 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 SMART SM00458 416 538 5.6E-24 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 SUPERFAMILY SSF51445 24 316 3.86E-86 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 Gene3D G3DSA:2.80.10.50 412 502 1.4E-25 T 12-10-2018 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 SUPERFAMILY SSF51011 318 403 5.76E-15 T 12-10-2018 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 Gene3D G3DSA:2.60.40.1180 318 405 6.5E-19 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 PRINTS PR00740 Glycosyl hydrolase family 27 signature 63 78 1.2E-47 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 PRINTS PR00740 Glycosyl hydrolase family 27 signature 145 162 1.2E-47 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 PRINTS PR00740 Glycosyl hydrolase family 27 signature 174 192 1.2E-47 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 PRINTS PR00740 Glycosyl hydrolase family 27 signature 27 46 1.2E-47 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 PRINTS PR00740 Glycosyl hydrolase family 27 signature 251 270 1.2E-47 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 PRINTS PR00740 Glycosyl hydrolase family 27 signature 272 293 1.2E-47 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 Gene3D G3DSA:2.80.10.50 503 538 2.8E-9 T 12-10-2018 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 Gene3D G3DSA:3.20.20.70 25 317 3.4E-118 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 SUPERFAMILY SSF50370 410 536 5.94E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 Pfam PF00652 Ricin-type beta-trefoil lectin domain 415 535 1.1E-25 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29165 71db2e0f2cb6557d9fd69eded985f37a 538 ProSitePatterns PS00512 Alpha-galactosidase signature. 68 84 - T 12-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 SUPERFAMILY SSF56425 250 366 1.45E-35 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 26 48 3.1E-5 T 12-10-2018 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 391 3.1E-5 T 12-10-2018 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 SUPERFAMILY SSF51905 11 424 8.77E-69 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 SUPERFAMILY SSF46977 444 538 2.62E-23 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 27 46 1.4E-10 T 12-10-2018 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 369 391 1.4E-10 T 12-10-2018 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 Gene3D G3DSA:1.20.58.100 439 536 3.5E-17 T 12-10-2018 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 24 520 3.7E-163 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 Pfam PF00890 FAD binding domain 26 406 1.2E-96 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 Pfam PF02910 Fumarate reductase flavoprotein C-term 446 535 1.4E-11 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 Gene3D G3DSA:3.90.700.10 259 361 6.4E-148 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_41380 f88c10400735b7ca76f33cf38284db1b 548 Gene3D G3DSA:3.50.50.60 26 416 6.4E-148 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_42745 c086d96f20d4d12d062fa256d2ec22c3 411 Pfam PF09594 Glycosyltransferase family 87 143 367 6.8E-14 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 AFR_25825 f8fdb717d71a449eae40c4f591596936 739 Gene3D G3DSA:2.60.40.10 179 268 2.5E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_25825 f8fdb717d71a449eae40c4f591596936 739 Gene3D G3DSA:1.50.10.10 271 739 1.3E-184 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_25825 f8fdb717d71a449eae40c4f591596936 739 Pfam PF00759 Glycosyl hydrolase family 9 272 731 2.6E-100 T 12-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 AFR_25825 f8fdb717d71a449eae40c4f591596936 739 SUPERFAMILY SSF81296 172 267 4.13E-22 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_25825 f8fdb717d71a449eae40c4f591596936 739 SUPERFAMILY SSF49785 29 167 5.61E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25825 f8fdb717d71a449eae40c4f591596936 739 Gene3D G3DSA:2.60.120.260 29 167 6.2E-27 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25825 f8fdb717d71a449eae40c4f591596936 739 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 708 726 - T 12-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 AFR_25825 f8fdb717d71a449eae40c4f591596936 739 SUPERFAMILY SSF48208 272 737 4.57E-126 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_25825 f8fdb717d71a449eae40c4f591596936 739 Pfam PF02927 Cellulase N-terminal ig-like domain 179 261 3.1E-24 T 12-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 AFR_25825 f8fdb717d71a449eae40c4f591596936 739 Pfam PF02018 Carbohydrate binding domain 30 153 3.4E-11 T 12-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 AFR_20690 d0ae204c7b052aae61f13ac61a0659f4 289 Gene3D G3DSA:3.20.20.70 2 289 2.4E-79 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_20690 d0ae204c7b052aae61f13ac61a0659f4 289 SUPERFAMILY SSF51569 31 285 2.67E-34 T 12-10-2018 AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 SMART SM00267 303 476 2.7E-51 T 12-10-2018 IPR000160 GGDEF domain AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 Pfam PF00563 EAL domain 491 720 8.4E-68 T 12-10-2018 IPR001633 EAL domain AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 Gene3D G3DSA:3.20.20.450 487 733 4.1E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 Gene3D G3DSA:3.30.70.270 309 476 6.5E-50 T 12-10-2018 AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 313 469 7.3E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 Pfam PF00990 Diguanylate cyclase, GGDEF domain 314 469 8.1E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 SMART SM00052 485 725 4.3E-97 T 12-10-2018 IPR001633 EAL domain AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 SUPERFAMILY SSF141868 490 730 2.48E-78 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02655 f31b19d733a9f4428f4d6dd80ec845a9 735 SUPERFAMILY SSF55073 319 470 9.42E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_03840 1a0ac4967f9824494b1059510940b535 120 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 24 111 2.1E-15 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_03840 1a0ac4967f9824494b1059510940b535 120 Gene3D G3DSA:3.30.750.24 9 118 1.1E-21 T 12-10-2018 IPR036513 STAS domain superfamily AFR_03840 1a0ac4967f9824494b1059510940b535 120 SUPERFAMILY SSF52091 24 112 3.92E-18 T 12-10-2018 IPR036513 STAS domain superfamily AFR_03840 1a0ac4967f9824494b1059510940b535 120 Pfam PF13466 STAS domain 26 103 2.1E-11 T 12-10-2018 IPR002645 STAS domain AFR_20725 5031c650acb63705e2794459028b3b23 271 Gene3D G3DSA:3.40.50.300 4 258 5.2E-52 T 12-10-2018 AFR_20725 5031c650acb63705e2794459028b3b23 271 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_20725 5031c650acb63705e2794459028b3b23 271 Pfam PF00005 ABC transporter 35 189 1.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20725 5031c650acb63705e2794459028b3b23 271 SUPERFAMILY SSF52540 17 247 8.1E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20725 5031c650acb63705e2794459028b3b23 271 SMART SM00382 44 237 5.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_16540 1378bffdedc28c7fac3888bcea0a5acf 394 Pfam PF07690 Major Facilitator Superfamily 23 271 5.6E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_16540 1378bffdedc28c7fac3888bcea0a5acf 394 Gene3D G3DSA:1.20.1250.20 4 385 2.6E-28 T 12-10-2018 AFR_16540 1378bffdedc28c7fac3888bcea0a5acf 394 SUPERFAMILY SSF103473 14 388 1.44E-30 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_28195 a8e57efe398083ca4b258734d21f6227 689 SMART SM00460 430 501 1.5E-11 T 12-10-2018 IPR002931 Transglutaminase-like AFR_28195 a8e57efe398083ca4b258734d21f6227 689 SUPERFAMILY SSF54001 376 508 3.92E-23 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_28195 a8e57efe398083ca4b258734d21f6227 689 Gene3D G3DSA:3.10.620.30 372 514 6.7E-18 T 12-10-2018 AFR_28195 a8e57efe398083ca4b258734d21f6227 689 Pfam PF01841 Transglutaminase-like superfamily 382 499 3.6E-21 T 12-10-2018 IPR002931 Transglutaminase-like AFR_39870 ce4a008f5cd36f0e1141fb3339f3d502 118 SUPERFAMILY SSF54593 2 116 5.21E-12 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_39870 ce4a008f5cd36f0e1141fb3339f3d502 118 Gene3D G3DSA:3.10.180.10 1 117 1.6E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 Pfam PF00107 Zinc-binding dehydrogenase 190 313 8.8E-29 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 SUPERFAMILY SSF50129 5 186 1.51E-53 T 12-10-2018 IPR011032 GroES-like superfamily AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 Gene3D G3DSA:3.40.50.720 167 304 3.4E-115 T 12-10-2018 AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 SUPERFAMILY SSF50129 310 361 2.45E-7 T 12-10-2018 IPR011032 GroES-like superfamily AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 8.2E-27 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 Gene3D G3DSA:3.90.180.10 10 358 3.4E-115 T 12-10-2018 AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 SUPERFAMILY SSF51735 155 326 1.83E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 360 2.4E-207 T 12-10-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase MetaCyc: PWY-7908 AFR_06250 dae5e4452a400231a5064bd172dce0bf 361 SMART SM00829 14 359 0.006 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_41665 09127d1e7e6d42ff805d693b668a1674 98 Pfam PF02467 Transcription factor WhiB 5 67 1.2E-23 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain AFR_41665 09127d1e7e6d42ff805d693b668a1674 98 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 72 18.022 T 12-10-2018 IPR003482 Transcription factor WhiB AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 Pfam PF00384 Molybdopterin oxidoreductase 96 521 3.5E-57 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 471 488 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 Pfam PF01568 Molydopterin dinucleotide binding domain 642 756 2.4E-30 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 SUPERFAMILY SSF53706 40 598 1.09E-148 T 12-10-2018 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 SMART SM00926 39 93 0.0032 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 Gene3D G3DSA:2.40.40.20 633 763 1.9E-42 T 12-10-2018 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 Gene3D G3DSA:3.40.228.10 175 376 1.6E-153 T 12-10-2018 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 SUPERFAMILY SSF50692 616 762 4.75E-40 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 Gene3D G3DSA:3.40.50.740 101 577 1.6E-153 T 12-10-2018 AFR_34065 024de35ff89cb9a70c97fb72af6ccb6a 768 Gene3D G3DSA:2.20.25.90 35 95 8.5E-6 T 12-10-2018 AFR_25605 0609dcfdf2600691683f5b91b1eb7542 394 Pfam PF12704 MacB-like periplasmic core domain 21 236 3.1E-29 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_25605 0609dcfdf2600691683f5b91b1eb7542 394 Pfam PF02687 FtsX-like permease family 300 387 1.8E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 Gene3D G3DSA:1.10.260.40 5 65 1.8E-20 T 12-10-2018 AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 Pfam PF13377 Periplasmic binding protein-like domain 183 337 2.8E-34 T 12-10-2018 AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 SUPERFAMILY SSF47413 11 69 7.74E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 SUPERFAMILY SSF53822 84 337 6.39E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 Gene3D G3DSA:3.40.50.2300 175 298 6.3E-71 T 12-10-2018 AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 Gene3D G3DSA:3.40.50.2300 66 315 6.3E-71 T 12-10-2018 AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 1.3E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_34935 126f0d95075d69800f1dc1b963b10f2f 338 SMART SM00354 11 81 4.0E-25 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SMART SM00645 67 280 5.0E-4 T 12-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Gene3D G3DSA:2.60.40.10 295 379 7.4E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SUPERFAMILY SSF81296 382 464 2.29E-10 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SUPERFAMILY SSF81296 466 549 1.11E-11 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SUPERFAMILY SSF54001 63 271 1.26E-22 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Pfam PF01833 IPT/TIG domain 555 636 1.8E-10 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Pfam PF01833 IPT/TIG domain 642 721 1.5E-8 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Pfam PF01833 IPT/TIG domain 383 462 2.2E-9 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Pfam PF01833 IPT/TIG domain 468 549 2.2E-10 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Pfam PF01833 IPT/TIG domain 296 378 6.6E-9 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Gene3D G3DSA:2.60.40.10 554 639 2.4E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Gene3D G3DSA:2.60.40.10 466 553 1.4E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Gene3D G3DSA:2.60.40.10 640 723 3.9E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SUPERFAMILY SSF81296 554 628 5.13E-13 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SMART SM00429 554 637 3.6 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SMART SM00429 382 463 0.0011 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SMART SM00429 641 722 0.58 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SMART SM00429 467 550 0.088 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SMART SM00429 295 379 0.044 T 12-10-2018 IPR002909 IPT domain AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Gene3D G3DSA:3.90.70.10 48 283 1.9E-31 T 12-10-2018 AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Gene3D G3DSA:2.60.40.10 380 465 1.7E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SUPERFAMILY SSF81296 295 380 9.92E-12 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 Pfam PF00112 Papain family cysteine protease 67 263 1.3E-8 T 12-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFR_34395 11c68058f2d9b1d07c4b681652fe7aa0 725 SUPERFAMILY SSF81296 640 720 1.75E-9 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 Pfam PF00072 Response regulator receiver domain 6 120 5.6E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 Gene3D G3DSA:3.40.50.12740 4 215 8.7E-68 T 12-10-2018 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 1.6E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 SMART SM00448 4 119 2.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 SUPERFAMILY SSF52172 3 129 8.97E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 SUPERFAMILY SSF46894 139 216 3.74E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 SMART SM00421 152 209 1.9E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20905 1aff446c501666cfcb65d6cf466370d1 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26335 551713c2b11b11683c6021c398c953b9 299 SMART SM00046 5 131 4.2E-4 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFR_26335 551713c2b11b11683c6021c398c953b9 299 Gene3D G3DSA:2.60.200.40 136 292 5.2E-38 T 12-10-2018 AFR_26335 551713c2b11b11683c6021c398c953b9 299 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 8 297 5.2E-35 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase AFR_26335 551713c2b11b11683c6021c398c953b9 299 SUPERFAMILY SSF111331 5 299 8.72E-68 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_26335 551713c2b11b11683c6021c398c953b9 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 129 8.4E-24 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFR_26335 551713c2b11b11683c6021c398c953b9 299 Gene3D G3DSA:3.40.50.10330 2 135 2.8E-27 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_16155 281ec1267c4cdb7a0349e8304e6bf700 707 SUPERFAMILY SSF82866 460 692 2.09E-21 T 12-10-2018 AFR_16155 281ec1267c4cdb7a0349e8304e6bf700 707 SUPERFAMILY SSF82866 114 340 7.19E-22 T 12-10-2018 AFR_16155 281ec1267c4cdb7a0349e8304e6bf700 707 Gene3D G3DSA:1.20.1640.10 177 349 1.2E-8 T 12-10-2018 AFR_16155 281ec1267c4cdb7a0349e8304e6bf700 707 Pfam PF03176 MMPL family 462 699 2.2E-25 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_16155 281ec1267c4cdb7a0349e8304e6bf700 707 Pfam PF03176 MMPL family 45 366 1.0E-43 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_18520 09fcc59cc9f8d3b776797fd8730aa0ee 588 Gene3D G3DSA:3.40.50.12780 8 449 2.9E-140 T 12-10-2018 AFR_18520 09fcc59cc9f8d3b776797fd8730aa0ee 588 Pfam PF00501 AMP-binding enzyme 15 457 3.0E-78 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_18520 09fcc59cc9f8d3b776797fd8730aa0ee 588 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_18520 09fcc59cc9f8d3b776797fd8730aa0ee 588 Gene3D G3DSA:3.30.300.30 451 578 5.5E-32 T 12-10-2018 AFR_18520 09fcc59cc9f8d3b776797fd8730aa0ee 588 SUPERFAMILY SSF56801 9 565 4.97E-100 T 12-10-2018 AFR_06375 e9f7cd8b220630c916af83a4559a7269 204 SUPERFAMILY SSF52972 3 198 2.88E-61 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFR_06375 e9f7cd8b220630c916af83a4559a7269 204 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 5 197 5.8E-47 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFR_06375 e9f7cd8b220630c916af83a4559a7269 204 Hamap MF_01405 dITP/XTP pyrophosphatase. 3 200 45.983 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 AFR_06375 e9f7cd8b220630c916af83a4559a7269 204 Pfam PF01725 Ham1 family 5 196 7.0E-53 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFR_06375 e9f7cd8b220630c916af83a4559a7269 204 Gene3D G3DSA:3.90.950.10 1 202 7.5E-68 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFR_26275 3ef650b6b84b4e8041963d72138c5032 115 Gene3D G3DSA:3.10.180.10 3 114 1.5E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_26275 3ef650b6b84b4e8041963d72138c5032 115 SUPERFAMILY SSF54593 4 112 2.01E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_26275 3ef650b6b84b4e8041963d72138c5032 115 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 110 1.6E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_06225 7f64fe983f43456e345b133156685ef2 565 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 56 132 6.6E-8 T 12-10-2018 IPR000014 PAS domain AFR_06225 7f64fe983f43456e345b133156685ef2 565 Pfam PF08447 PAS fold 33 119 5.3E-8 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_06225 7f64fe983f43456e345b133156685ef2 565 SMART SM00052 311 552 2.0E-66 T 12-10-2018 IPR001633 EAL domain AFR_06225 7f64fe983f43456e345b133156685ef2 565 SMART SM00267 136 303 3.6E-5 T 12-10-2018 IPR000160 GGDEF domain AFR_06225 7f64fe983f43456e345b133156685ef2 565 Pfam PF00563 EAL domain 318 547 2.6E-65 T 12-10-2018 IPR001633 EAL domain AFR_06225 7f64fe983f43456e345b133156685ef2 565 SUPERFAMILY SSF55785 22 128 3.14E-13 T 12-10-2018 IPR035965 PAS domain superfamily AFR_06225 7f64fe983f43456e345b133156685ef2 565 Gene3D G3DSA:3.30.70.270 145 304 2.2E-16 T 12-10-2018 AFR_06225 7f64fe983f43456e345b133156685ef2 565 SMART SM00086 84 126 9.6E-6 T 12-10-2018 IPR001610 PAC motif AFR_06225 7f64fe983f43456e345b133156685ef2 565 Pfam PF00990 Diguanylate cyclase, GGDEF domain 151 297 3.4E-5 T 12-10-2018 IPR000160 GGDEF domain AFR_06225 7f64fe983f43456e345b133156685ef2 565 SUPERFAMILY SSF141868 318 554 1.57E-73 T 12-10-2018 IPR035919 EAL domain superfamily AFR_06225 7f64fe983f43456e345b133156685ef2 565 Gene3D G3DSA:3.20.20.450 310 561 1.2E-78 T 12-10-2018 IPR035919 EAL domain superfamily AFR_06225 7f64fe983f43456e345b133156685ef2 565 Gene3D G3DSA:3.30.450.20 20 131 1.7E-14 T 12-10-2018 AFR_06225 7f64fe983f43456e345b133156685ef2 565 SUPERFAMILY SSF55073 154 302 4.47E-14 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_27355 b9beea36ec504834f142432eb5fda904 337 Pfam PF13377 Periplasmic binding protein-like domain 171 334 2.7E-17 T 12-10-2018 AFR_27355 b9beea36ec504834f142432eb5fda904 337 Gene3D G3DSA:3.40.50.2300 160 292 2.2E-31 T 12-10-2018 AFR_27355 b9beea36ec504834f142432eb5fda904 337 SUPERFAMILY SSF47413 1 59 2.23E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_27355 b9beea36ec504834f142432eb5fda904 337 SMART SM00354 1 76 1.9E-26 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_27355 b9beea36ec504834f142432eb5fda904 337 Gene3D G3DSA:1.10.260.40 1 55 7.9E-23 T 12-10-2018 AFR_27355 b9beea36ec504834f142432eb5fda904 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 48 1.6E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_27355 b9beea36ec504834f142432eb5fda904 337 Gene3D G3DSA:3.40.50.2300 56 309 2.2E-31 T 12-10-2018 AFR_27355 b9beea36ec504834f142432eb5fda904 337 SUPERFAMILY SSF53822 58 314 3.77E-25 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_35515 d3b51350d8e4400c7e687d8f9697dc24 102 Pfam PF01476 LysM domain 52 99 1.2E-8 T 12-10-2018 IPR018392 LysM domain AFR_35515 d3b51350d8e4400c7e687d8f9697dc24 102 SMART SM00257 50 99 1.3E-7 T 12-10-2018 IPR018392 LysM domain AFR_35515 d3b51350d8e4400c7e687d8f9697dc24 102 Gene3D G3DSA:3.10.350.10 48 99 2.6E-12 T 12-10-2018 IPR036779 LysM domain superfamily AFR_35515 d3b51350d8e4400c7e687d8f9697dc24 102 SUPERFAMILY SSF54106 52 99 1.83E-6 T 12-10-2018 AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 416 426 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 PRINTS PR00723 Subtilisin serine protease family (S8) signature 239 252 3.1E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 221 3.1E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 PRINTS PR00723 Subtilisin serine protease family (S8) signature 415 431 3.1E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 Gene3D G3DSA:3.40.50.200 177 476 1.9E-100 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 SUPERFAMILY SSF52743 183 474 1.57E-84 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 Pfam PF00082 Subtilase family 202 465 4.4E-60 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_34550 56a5a3b5f3640199bb2b9710289774e4 1168 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 207 218 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_35175 640610d0caae5941421ced17060f887a 334 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 2 332 5.9E-125 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFR_35175 640610d0caae5941421ced17060f887a 334 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 1 334 45.61 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFR_35175 640610d0caae5941421ced17060f887a 334 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 132 148 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFR_35175 640610d0caae5941421ced17060f887a 334 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 2 333 1.1E-124 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFR_35175 640610d0caae5941421ced17060f887a 334 SUPERFAMILY SSF51726 2 333 3.31E-104 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFR_35175 640610d0caae5941421ced17060f887a 334 Gene3D G3DSA:3.20.20.210 1 334 7.6E-144 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFR_35175 640610d0caae5941421ced17060f887a 334 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 15 24 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 SUPERFAMILY SSF54427 200 316 1.52E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 Gene3D G3DSA:3.10.450.50 196 317 2.2E-15 T 12-10-2018 AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 SUPERFAMILY SSF88946 7 95 1.57E-27 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 Gene3D G3DSA:1.10.1740.10 2 103 1.9E-28 T 12-10-2018 AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 16 318 8.2E-90 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 189 8.8E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 SUPERFAMILY SSF88659 136 189 1.87E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 Pfam PF08281 Sigma-70, region 4 141 188 8.6E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 Pfam PF04542 Sigma-70 region 2 23 90 1.9E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 Pfam PF12680 SnoaL-like domain 205 301 5.0E-7 T 12-10-2018 IPR037401 SnoaL-like domain AFR_03650 c79fe757a0a37848bf9c73af3b77d41e 319 Gene3D G3DSA:1.10.10.10 137 195 2.4E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19830 3261a9331271af39a22faf80217d824e 336 Pfam PF16884 N-terminal domain of oxidoreductase 8 113 4.3E-37 T 12-10-2018 AFR_19830 3261a9331271af39a22faf80217d824e 336 Gene3D G3DSA:3.40.50.720 126 303 6.0E-130 T 12-10-2018 AFR_19830 3261a9331271af39a22faf80217d824e 336 SUPERFAMILY SSF50129 5 140 6.06E-36 T 12-10-2018 IPR011032 GroES-like superfamily AFR_19830 3261a9331271af39a22faf80217d824e 336 Gene3D G3DSA:3.90.180.10 20 331 6.0E-130 T 12-10-2018 AFR_19830 3261a9331271af39a22faf80217d824e 336 SUPERFAMILY SSF51735 123 299 2.2E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19830 3261a9331271af39a22faf80217d824e 336 Pfam PF00107 Zinc-binding dehydrogenase 158 286 1.7E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_19830 3261a9331271af39a22faf80217d824e 336 SMART SM00829 19 332 1.6E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_36115 8a5735e362aa5f60c259d3d8f33a8b3a 714 Pfam PF12698 ABC-2 family transporter protein 501 694 6.0E-16 T 12-10-2018 AFR_36115 8a5735e362aa5f60c259d3d8f33a8b3a 714 SUPERFAMILY SSF58104 228 452 3.01E-7 T 12-10-2018 AFR_36115 8a5735e362aa5f60c259d3d8f33a8b3a 714 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 496 701 3.2E-65 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal AFR_36115 8a5735e362aa5f60c259d3d8f33a8b3a 714 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 13 178 1.6E-46 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal AFR_34795 d02fa5c2571ca9f18129ad62590a682f 327 SMART SM01092 224 322 4.7E-27 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_34795 d02fa5c2571ca9f18129ad62590a682f 327 Gene3D G3DSA:3.30.390.50 221 324 6.4E-25 T 12-10-2018 AFR_34795 d02fa5c2571ca9f18129ad62590a682f 327 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 217 1.2E-49 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFR_34795 d02fa5c2571ca9f18129ad62590a682f 327 SUPERFAMILY SSF56176 1 217 1.03E-57 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_34795 d02fa5c2571ca9f18129ad62590a682f 327 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 224 320 3.4E-17 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_34795 d02fa5c2571ca9f18129ad62590a682f 327 SUPERFAMILY SSF55447 222 323 1.7E-26 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily AFR_34795 d02fa5c2571ca9f18129ad62590a682f 327 Gene3D G3DSA:3.30.465.10 1 218 5.2E-83 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_30080 546879a39a710d718862d9a47e0ca249 281 Gene3D G3DSA:3.40.1190.20 14 281 1.1E-60 T 12-10-2018 IPR029056 Ribokinase-like AFR_30080 546879a39a710d718862d9a47e0ca249 281 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 11 279 17.821 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFR_30080 546879a39a710d718862d9a47e0ca249 281 SUPERFAMILY SSF53613 10 275 6.55E-49 T 12-10-2018 IPR029056 Ribokinase-like AFR_30080 546879a39a710d718862d9a47e0ca249 281 Pfam PF01256 Carbohydrate kinase 34 273 1.5E-43 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFR_30080 546879a39a710d718862d9a47e0ca249 281 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 13 277 3.4E-46 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFR_09965 b8e73f56cac06e89c809817b64a35b5d 257 Gene3D G3DSA:3.90.1720.10 88 255 1.9E-30 T 12-10-2018 AFR_09965 b8e73f56cac06e89c809817b64a35b5d 257 SUPERFAMILY SSF54001 136 249 5.4E-28 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_09965 b8e73f56cac06e89c809817b64a35b5d 257 Pfam PF00877 NlpC/P60 family 154 251 6.7E-20 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 Pfam PF04542 Sigma-70 region 2 13 73 8.8E-5 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 Gene3D G3DSA:1.10.10.10 75 160 5.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 Pfam PF08281 Sigma-70, region 4 99 150 1.0E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 Gene3D G3DSA:1.10.1740.10 1 74 1.2E-7 T 12-10-2018 AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 SUPERFAMILY SSF88946 3 83 2.94E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 152 2.1E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 SUPERFAMILY SSF88659 92 152 2.99E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_34105 20b0e42e286a3552e19be38ad3f10bf6 166 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 156 8.5E-52 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Gene3D G3DSA:1.10.1790.20 1018 1197 2.4E-65 T 12-10-2018 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Gene3D G3DSA:1.10.132.30 725 859 7.1E-51 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Gene3D G3DSA:1.10.274.100 565 724 1.2E-41 T 12-10-2018 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Gene3D G3DSA:1.10.40.90 449 491 2.3E-23 T 12-10-2018 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Gene3D G3DSA:1.10.150.390 1199 1262 6.6E-28 T 12-10-2018 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Pfam PF00623 RNA polymerase Rpb1, domain 2 467 560 2.4E-28 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 462 4.1E-8 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Pfam PF04998 RNA polymerase Rpb1, domain 5 835 1197 3.7E-64 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Gene3D G3DSA:2.40.50.100 1034 1098 2.4E-65 T 12-10-2018 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 SUPERFAMILY SSF64484 5 1251 0.0 T 12-10-2018 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Pfam PF05000 RNA polymerase Rpb1, domain 4 759 823 2.2E-10 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1260 17.579 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 SMART SM00663 310 589 1.2E-177 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 2.6E-81 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 728 4.1E-24 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_04465 77fa9f2f753fccce6906d30049b209ff 1296 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1250 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_40610 76de3c30c02f67a2a31816555cdd50cb 169 SUPERFAMILY SSF55797 48 167 1.33E-19 T 12-10-2018 IPR035940 CAP superfamily AFR_40610 76de3c30c02f67a2a31816555cdd50cb 169 Pfam PF00188 Cysteine-rich secretory protein family 52 166 4.0E-16 T 12-10-2018 IPR014044 CAP domain AFR_40610 76de3c30c02f67a2a31816555cdd50cb 169 Gene3D G3DSA:3.40.33.10 21 167 2.5E-38 T 12-10-2018 IPR035940 CAP superfamily AFR_36360 7e538d9a68e2a5c88c1727b65bd04b51 358 Pfam PF01979 Amidohydrolase family 41 342 4.0E-15 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_36360 7e538d9a68e2a5c88c1727b65bd04b51 358 Gene3D G3DSA:2.30.40.10 31 356 5.1E-50 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_36360 7e538d9a68e2a5c88c1727b65bd04b51 358 SUPERFAMILY SSF51556 45 321 1.94E-56 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_36360 7e538d9a68e2a5c88c1727b65bd04b51 358 Gene3D G3DSA:3.20.20.140 47 320 5.1E-50 T 12-10-2018 AFR_09770 14f44cbd9b2b8809da1fd9533d11feec 205 SUPERFAMILY SSF46689 8 72 9.75E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_09770 14f44cbd9b2b8809da1fd9533d11feec 205 Gene3D G3DSA:1.10.10.60 3 60 2.2E-14 T 12-10-2018 AFR_09770 14f44cbd9b2b8809da1fd9533d11feec 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 2.6E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09770 14f44cbd9b2b8809da1fd9533d11feec 205 Gene3D G3DSA:1.10.357.10 61 205 6.2E-19 T 12-10-2018 AFR_09770 14f44cbd9b2b8809da1fd9533d11feec 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09770 14f44cbd9b2b8809da1fd9533d11feec 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09770 14f44cbd9b2b8809da1fd9533d11feec 205 SUPERFAMILY SSF48498 86 203 3.67E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_35950 bd8f2c1a76af433fc7b5a1bda76baf73 439 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 409 1.5E-88 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_35950 bd8f2c1a76af433fc7b5a1bda76baf73 439 PIRSF PIRSF006603 5 439 4.1E-54 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_35950 bd8f2c1a76af433fc7b5a1bda76baf73 439 Pfam PF01554 MatE 251 394 4.1E-16 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_35950 bd8f2c1a76af433fc7b5a1bda76baf73 439 Pfam PF01554 MatE 22 182 2.6E-28 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_13375 7f92474da731426f2f6719eb929849e0 201 Gene3D G3DSA:1.10.357.10 9 200 1.5E-31 T 12-10-2018 AFR_13375 7f92474da731426f2f6719eb929849e0 201 SUPERFAMILY SSF48498 83 195 2.45E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13375 7f92474da731426f2f6719eb929849e0 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 8.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13375 7f92474da731426f2f6719eb929849e0 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 8.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13375 7f92474da731426f2f6719eb929849e0 201 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 87 179 8.0E-10 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_13375 7f92474da731426f2f6719eb929849e0 201 SUPERFAMILY SSF46689 8 75 2.15E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13375 7f92474da731426f2f6719eb929849e0 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 1.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33365 70f2157ae0412744cfb383af0ced8697 152 Gene3D G3DSA:2.40.50.140 93 151 4.0E-6 T 12-10-2018 AFR_33365 70f2157ae0412744cfb383af0ced8697 152 Pfam PF00575 S1 RNA binding domain 6 78 7.6E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_33365 70f2157ae0412744cfb383af0ced8697 152 Pfam PF00575 S1 RNA binding domain 93 122 2.5E-4 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_33365 70f2157ae0412744cfb383af0ced8697 152 SMART SM00316 7 78 9.0E-15 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_33365 70f2157ae0412744cfb383af0ced8697 152 SMART SM00316 92 151 4.3E-4 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_33365 70f2157ae0412744cfb383af0ced8697 152 SUPERFAMILY SSF50249 76 148 4.55E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_33365 70f2157ae0412744cfb383af0ced8697 152 Gene3D G3DSA:2.40.50.140 3 92 1.5E-20 T 12-10-2018 AFR_33365 70f2157ae0412744cfb383af0ced8697 152 SUPERFAMILY SSF50249 3 84 1.42E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_24735 9cb3f14b8295b7358ddfef5bc2f0147b 147 SUPERFAMILY SSF46458 1 122 8.84E-22 T 12-10-2018 IPR009050 Globin-like superfamily AFR_24735 9cb3f14b8295b7358ddfef5bc2f0147b 147 Pfam PF01152 Bacterial-like globin 2 101 5.7E-14 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 AFR_24735 9cb3f14b8295b7358ddfef5bc2f0147b 147 Gene3D G3DSA:1.10.490.10 1 124 8.0E-24 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFR_20780 15cdfcdfb761f1839645406581bc1108 215 Gene3D G3DSA:1.10.357.10 86 213 5.1E-34 T 12-10-2018 AFR_20780 15cdfcdfb761f1839645406581bc1108 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 80 4.6E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_20780 15cdfcdfb761f1839645406581bc1108 215 SUPERFAMILY SSF48498 102 213 2.36E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_20780 15cdfcdfb761f1839645406581bc1108 215 Gene3D G3DSA:1.10.10.60 17 85 9.4E-21 T 12-10-2018 AFR_20780 15cdfcdfb761f1839645406581bc1108 215 SUPERFAMILY SSF46689 22 107 6.8E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_20780 15cdfcdfb761f1839645406581bc1108 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 1.4E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_20780 15cdfcdfb761f1839645406581bc1108 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 1.4E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 SUPERFAMILY SSF51735 3 249 7.25E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 186 2.0E-4 T 12-10-2018 AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 Gene3D G3DSA:3.40.50.720 2 252 2.1E-69 T 12-10-2018 AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 5.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 5.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 2.1E-51 T 12-10-2018 AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 5.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 5.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03375 f8b7060e392f4862c0cf1351c13a4e25 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.3E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33540 78ff6dfbccf96250b6d798b580238af3 146 Hamap MF_00042 Ribonuclease H [rnhA]. 1 146 30.458 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 AFR_33540 78ff6dfbccf96250b6d798b580238af3 146 Gene3D G3DSA:3.30.420.10 1 144 6.9E-54 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_33540 78ff6dfbccf96250b6d798b580238af3 146 SUPERFAMILY SSF53098 1 140 1.9E-53 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_33540 78ff6dfbccf96250b6d798b580238af3 146 Pfam PF00075 RNase H 1 139 2.4E-47 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AFR_05385 a0ab6aeb860d76059ff0df5e65fe2362 456 Pfam PF01882 Protein of unknown function DUF58 218 306 7.1E-18 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_35630 f57e0a399c48c02d392696269257248d 274 Gene3D G3DSA:1.10.260.40 4 84 1.0E-6 T 12-10-2018 AFR_35630 f57e0a399c48c02d392696269257248d 274 SUPERFAMILY SSF47413 29 80 3.1E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_35630 f57e0a399c48c02d392696269257248d 274 Pfam PF13560 Helix-turn-helix domain 5 84 8.7E-17 T 12-10-2018 AFR_35630 f57e0a399c48c02d392696269257248d 274 SMART SM00530 9 81 3.9E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_21255 703c1b4cb58d9c6486394af9de3d3dd3 326 Gene3D G3DSA:3.40.50.720 1 296 7.9E-31 T 12-10-2018 AFR_21255 703c1b4cb58d9c6486394af9de3d3dd3 326 SUPERFAMILY SSF51735 2 250 3.48E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_21255 703c1b4cb58d9c6486394af9de3d3dd3 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 89 201 1.4E-5 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_08815 593a59c6d0ba062011ab0f831afb989c 97 Pfam PF01337 Barstar (barnase inhibitor) 5 84 3.2E-11 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) AFR_08815 593a59c6d0ba062011ab0f831afb989c 97 Gene3D G3DSA:3.30.370.10 1 87 1.4E-8 T 12-10-2018 IPR035905 Barstar-like superfamily AFR_08815 593a59c6d0ba062011ab0f831afb989c 97 SUPERFAMILY SSF52038 3 85 1.31E-10 T 12-10-2018 IPR035905 Barstar-like superfamily AFR_21670 f10b05ae203cc9412809215e4f4accb3 411 Gene3D G3DSA:3.40.190.10 49 367 5.8E-107 T 12-10-2018 AFR_21670 f10b05ae203cc9412809215e4f4accb3 411 Gene3D G3DSA:3.40.190.10 143 403 5.8E-107 T 12-10-2018 AFR_21670 f10b05ae203cc9412809215e4f4accb3 411 Pfam PF13416 Bacterial extracellular solute-binding protein 50 351 3.9E-43 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_21670 f10b05ae203cc9412809215e4f4accb3 411 SUPERFAMILY SSF53850 34 403 1.32E-87 T 12-10-2018 AFR_07825 6dbd78ab665a5c1018519565a37de52c 258 SUPERFAMILY SSF52096 2 252 1.78E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_07825 6dbd78ab665a5c1018519565a37de52c 258 Gene3D G3DSA:3.90.226.10 2 179 3.7E-51 T 12-10-2018 AFR_07825 6dbd78ab665a5c1018519565a37de52c 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 252 4.8E-44 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_07825 6dbd78ab665a5c1018519565a37de52c 258 Gene3D G3DSA:1.10.12.10 199 253 1.4E-17 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFR_19010 5470a262cdbc473a7cccaf00d60c7422 389 Pfam PF07728 AAA domain (dynein-related subfamily) 39 172 1.5E-7 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFR_19010 5470a262cdbc473a7cccaf00d60c7422 389 SUPERFAMILY SSF52540 24 181 1.32E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19010 5470a262cdbc473a7cccaf00d60c7422 389 Gene3D G3DSA:3.40.50.300 23 184 6.2E-22 T 12-10-2018 AFR_19010 5470a262cdbc473a7cccaf00d60c7422 389 SMART SM00382 36 182 1.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41335 3eb434af207cee492b16617fa06c57e4 183 Hamap MF_00163 Peptide deformylase [def]. 18 180 21.666 T 12-10-2018 IPR023635 Peptide deformylase AFR_41335 3eb434af207cee492b16617fa06c57e4 183 Gene3D G3DSA:3.90.45.10 12 181 1.0E-40 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_41335 3eb434af207cee492b16617fa06c57e4 183 Pfam PF01327 Polypeptide deformylase 20 171 8.0E-36 T 12-10-2018 IPR023635 Peptide deformylase AFR_41335 3eb434af207cee492b16617fa06c57e4 183 SUPERFAMILY SSF56420 19 178 3.27E-39 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_41335 3eb434af207cee492b16617fa06c57e4 183 PIRSF PIRSF004749 7 180 1.4E-40 T 12-10-2018 IPR023635 Peptide deformylase AFR_41335 3eb434af207cee492b16617fa06c57e4 183 PRINTS PR01576 Peptide deformylase signature 111 122 3.7E-19 T 12-10-2018 IPR023635 Peptide deformylase AFR_41335 3eb434af207cee492b16617fa06c57e4 183 PRINTS PR01576 Peptide deformylase signature 50 79 3.7E-19 T 12-10-2018 IPR023635 Peptide deformylase AFR_41335 3eb434af207cee492b16617fa06c57e4 183 PRINTS PR01576 Peptide deformylase signature 143 172 3.7E-19 T 12-10-2018 IPR023635 Peptide deformylase AFR_24850 356776bbeb80a33707c65966a7e92c8c 121 Pfam PF13466 STAS domain 22 101 4.2E-14 T 12-10-2018 IPR002645 STAS domain AFR_24850 356776bbeb80a33707c65966a7e92c8c 121 Gene3D G3DSA:3.30.750.24 7 120 7.3E-28 T 12-10-2018 IPR036513 STAS domain superfamily AFR_24850 356776bbeb80a33707c65966a7e92c8c 121 SUPERFAMILY SSF52091 16 116 1.41E-22 T 12-10-2018 IPR036513 STAS domain superfamily AFR_39065 f231abf9f25c36052b471a258320c4a1 200 Gene3D G3DSA:2.40.380.10 1 185 1.1E-43 T 12-10-2018 IPR035930 FomD-like superfamily AFR_39065 f231abf9f25c36052b471a258320c4a1 200 SUPERFAMILY SSF159234 78 186 7.98E-17 T 12-10-2018 IPR035930 FomD-like superfamily AFR_39065 f231abf9f25c36052b471a258320c4a1 200 Pfam PF04167 Protein of unknown function (DUF402) 83 147 1.7E-12 T 12-10-2018 IPR007295 Domain of unknown function DUF402 AFR_34855 4d182cd14e9d369a3321e94070e45847 242 Gene3D G3DSA:3.40.50.1000 82 240 1.4E-32 T 12-10-2018 IPR023214 HAD superfamily AFR_34855 4d182cd14e9d369a3321e94070e45847 242 SUPERFAMILY SSF56784 6 240 1.68E-34 T 12-10-2018 IPR036412 HAD-like superfamily AFR_34855 4d182cd14e9d369a3321e94070e45847 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 120 202 6.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_34855 4d182cd14e9d369a3321e94070e45847 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 107 204 4.3E-16 T 12-10-2018 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 SUPERFAMILY SSF47384 200 264 9.22E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 415 1.3E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 SMART SM00388 216 274 4.4E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 267 1.6E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 Pfam PF00672 HAMP domain 163 212 3.3E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 SMART SM00304 163 215 8.5E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 SMART SM00387 317 419 1.8E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 SUPERFAMILY SSF55874 274 415 6.42E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 Gene3D G3DSA:1.10.287.130 160 269 6.7E-17 T 12-10-2018 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 Gene3D G3DSA:3.30.565.10 275 421 6.3E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 2.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 2.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_10215 3f40be44283517f092f56ba928d9f9e2 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 2.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31620 aa93b2799f615dd6e078fa700b9060f3 483 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_31620 aa93b2799f615dd6e078fa700b9060f3 483 Gene3D G3DSA:3.40.50.12780 7 383 9.9E-40 T 12-10-2018 AFR_31620 aa93b2799f615dd6e078fa700b9060f3 483 SUPERFAMILY SSF56801 8 482 7.85E-56 T 12-10-2018 AFR_31620 aa93b2799f615dd6e078fa700b9060f3 483 Pfam PF00501 AMP-binding enzyme 14 386 4.6E-35 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_31620 aa93b2799f615dd6e078fa700b9060f3 483 Gene3D G3DSA:3.30.300.30 384 461 8.0E-9 T 12-10-2018 AFR_03010 bf00882af01706258bea0bc7c36ebe91 401 Gene3D G3DSA:3.10.50.10 300 360 7.6E-123 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily AFR_03010 bf00882af01706258bea0bc7c36ebe91 401 SUPERFAMILY SSF54556 297 356 3.51E-11 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily AFR_03010 bf00882af01706258bea0bc7c36ebe91 401 SUPERFAMILY SSF51445 27 399 3.22E-80 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_03010 bf00882af01706258bea0bc7c36ebe91 401 SMART SM00636 34 385 3.8E-105 T 12-10-2018 IPR011583 Chitinase II GO:0008061 AFR_03010 bf00882af01706258bea0bc7c36ebe91 401 Pfam PF00704 Glycosyl hydrolases family 18 35 385 2.1E-69 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_03010 bf00882af01706258bea0bc7c36ebe91 401 ProSitePatterns PS01095 Chitinases family 18 active site. 168 176 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_03010 bf00882af01706258bea0bc7c36ebe91 401 Gene3D G3DSA:3.20.20.80 38 386 7.6E-123 T 12-10-2018 AFR_38805 a47c7c8598abf6fb4555f7b2971d318b 458 Gene3D G3DSA:3.30.2290.10 1 210 2.9E-8 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal AFR_38805 a47c7c8598abf6fb4555f7b2971d318b 458 Pfam PF01523 Putative modulator of DNA gyrase 24 295 1.0E-38 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFR_38805 a47c7c8598abf6fb4555f7b2971d318b 458 SUPERFAMILY SSF111283 7 454 1.57E-61 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 SUPERFAMILY SSF52172 1 127 9.08E-13 T 12-10-2018 IPR011006 CheY-like superfamily AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 Gene3D G3DSA:3.40.50.12740 2 199 5.9E-37 T 12-10-2018 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 4.9E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 SMART SM00421 138 195 1.1E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 SUPERFAMILY SSF46894 124 201 2.14E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_03780 2ed1d4cd8865f06e9d339ae5692561bb 202 Pfam PF00072 Response regulator receiver domain 4 111 2.1E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_05725 7e61ee032d542ed599f1ca2e5fa835bc 407 Gene3D G3DSA:3.40.50.10490 322 399 2.3E-5 T 12-10-2018 AFR_05725 7e61ee032d542ed599f1ca2e5fa835bc 407 SUPERFAMILY SSF53697 77 392 7.79E-68 T 12-10-2018 AFR_05725 7e61ee032d542ed599f1ca2e5fa835bc 407 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 221 397 2.5E-48 T 12-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 AFR_05725 7e61ee032d542ed599f1ca2e5fa835bc 407 Gene3D G3DSA:3.40.50.10490 44 200 1.7E-20 T 12-10-2018 AFR_22405 d0e68147c6a2017b72a577d0dc7b7ad5 454 Pfam PF13520 Amino acid permease 28 413 3.8E-46 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_22405 d0e68147c6a2017b72a577d0dc7b7ad5 454 PIRSF PIRSF006060 4 453 6.5E-80 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_22405 d0e68147c6a2017b72a577d0dc7b7ad5 454 Gene3D G3DSA:1.20.1740.10 17 454 4.3E-84 T 12-10-2018 AFR_14280 d28166c094c0703a845d0c6b5e3334c7 350 Gene3D G3DSA:3.90.180.10 16 346 7.8E-102 T 12-10-2018 AFR_14280 d28166c094c0703a845d0c6b5e3334c7 350 Pfam PF16912 Glucose dehydrogenase C-terminus 145 348 4.7E-65 T 12-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 AFR_14280 d28166c094c0703a845d0c6b5e3334c7 350 SUPERFAMILY SSF50129 13 191 1.0E-29 T 12-10-2018 IPR011032 GroES-like superfamily AFR_14280 d28166c094c0703a845d0c6b5e3334c7 350 SUPERFAMILY SSF51735 143 300 4.55E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14280 d28166c094c0703a845d0c6b5e3334c7 350 Gene3D G3DSA:3.40.50.720 147 322 7.8E-102 T 12-10-2018 AFR_14280 d28166c094c0703a845d0c6b5e3334c7 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 2.7E-12 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_29990 e553df91f35c0d6a423b50393ee94d39 307 SUPERFAMILY SSF48452 70 175 1.01E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_29990 e553df91f35c0d6a423b50393ee94d39 307 Gene3D G3DSA:1.25.40.10 5 226 2.1E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 PIRSF PIRSF000728 8 287 3.0E-99 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 TIGRFAM TIGR00761 argB: acetylglutamate kinase 24 262 4.0E-76 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 Hamap MF_00082 Acetylglutamate kinase [argB]. 22 280 46.658 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 SUPERFAMILY SSF53633 3 287 1.17E-85 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 Pfam PF00696 Amino acid kinase family 24 263 3.4E-45 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 PRINTS PR00474 Glutamate 5-kinase family signature 54 68 1.9E-8 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 PRINTS PR00474 Glutamate 5-kinase family signature 186 213 1.9E-8 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 PRINTS PR00474 Glutamate 5-kinase family signature 237 257 1.9E-8 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFR_30235 471eb2ba373ad65a34cef369119fa4a3 288 Gene3D G3DSA:3.40.1160.10 1 288 3.2E-101 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_18170 e1e83bd8f29074b33b37979838c150b2 527 SUPERFAMILY SSF54373 365 473 2.62E-22 T 12-10-2018 AFR_18170 e1e83bd8f29074b33b37979838c150b2 527 Gene3D G3DSA:3.50.50.60 61 518 4.1E-166 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18170 e1e83bd8f29074b33b37979838c150b2 527 Pfam PF01593 Flavin containing amine oxidoreductase 68 520 1.3E-37 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_18170 e1e83bd8f29074b33b37979838c150b2 527 SUPERFAMILY SSF51905 57 523 1.11E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18170 e1e83bd8f29074b33b37979838c150b2 527 Gene3D G3DSA:1.20.1440.240 171 275 4.1E-166 T 12-10-2018 AFR_18170 e1e83bd8f29074b33b37979838c150b2 527 Gene3D G3DSA:3.90.660.10 98 468 4.1E-166 T 12-10-2018 AFR_31440 cf444a9261ef5e0f09f22ba523fea617 366 Gene3D G3DSA:1.20.1250.20 7 173 9.4E-11 T 12-10-2018 AFR_31440 cf444a9261ef5e0f09f22ba523fea617 366 Gene3D G3DSA:1.20.1250.20 202 365 1.5E-9 T 12-10-2018 AFR_31440 cf444a9261ef5e0f09f22ba523fea617 366 SUPERFAMILY SSF103473 9 363 4.58E-23 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_04970 318060502d532db0e0948ffd0af63fca 592 Gene3D G3DSA:3.40.50.200 117 410 4.0E-72 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_04970 318060502d532db0e0948ffd0af63fca 592 Gene3D G3DSA:2.60.40.10 505 591 5.0E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_04970 318060502d532db0e0948ffd0af63fca 592 Gene3D G3DSA:2.60.40.10 413 503 1.3E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_04970 318060502d532db0e0948ffd0af63fca 592 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 350 360 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_04970 318060502d532db0e0948ffd0af63fca 592 Gene3D G3DSA:3.30.70.80 34 116 1.0E-6 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 AFR_04970 318060502d532db0e0948ffd0af63fca 592 SUPERFAMILY SSF52743 133 406 3.27E-64 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_04970 318060502d532db0e0948ffd0af63fca 592 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 189 199 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_04970 318060502d532db0e0948ffd0af63fca 592 Pfam PF00082 Subtilase family 149 391 1.7E-37 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_04970 318060502d532db0e0948ffd0af63fca 592 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 167 1.5E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_04970 318060502d532db0e0948ffd0af63fca 592 PRINTS PR00723 Subtilisin serine protease family (S8) signature 349 365 1.5E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_04970 318060502d532db0e0948ffd0af63fca 592 PRINTS PR00723 Subtilisin serine protease family (S8) signature 185 198 1.5E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 SUPERFAMILY SSF52540 35 254 3.15E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 Gene3D G3DSA:1.10.8.60 187 254 1.7E-12 T 12-10-2018 AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 SUPERFAMILY SSF48019 271 454 1.93E-73 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 Gene3D G3DSA:1.10.3710.10 364 458 9.3E-25 T 12-10-2018 AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 SMART SM00382 70 187 2.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 Gene3D G3DSA:3.40.50.300 29 186 1.1E-38 T 12-10-2018 AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 74 179 6.6E-17 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 Pfam PF16193 AAA C-terminal domain 209 285 6.2E-26 T 12-10-2018 IPR032423 AAA C-terminal domain AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 Gene3D G3DSA:1.20.272.10 259 363 7.4E-47 T 12-10-2018 AFR_30740 db5f5c583e929422b7b8799ba639bd84 585 Pfam PF12002 MgsA AAA+ ATPase C terminal 286 451 6.5E-70 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal AFR_16230 266676fa49fae212e5a41cf988adaab5 404 SUPERFAMILY SSF53067 215 397 8.05E-39 T 12-10-2018 AFR_16230 266676fa49fae212e5a41cf988adaab5 404 SUPERFAMILY SSF46785 21 85 1.31E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16230 266676fa49fae212e5a41cf988adaab5 404 Gene3D G3DSA:1.10.10.10 15 87 3.9E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16230 266676fa49fae212e5a41cf988adaab5 404 Gene3D G3DSA:3.30.420.40 214 374 4.6E-58 T 12-10-2018 AFR_16230 266676fa49fae212e5a41cf988adaab5 404 Pfam PF00480 ROK family 100 387 1.2E-38 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_16230 266676fa49fae212e5a41cf988adaab5 404 SUPERFAMILY SSF53067 93 213 4.7E-9 T 12-10-2018 AFR_16230 266676fa49fae212e5a41cf988adaab5 404 Gene3D G3DSA:3.30.420.40 102 384 4.6E-58 T 12-10-2018 AFR_05120 1657d56620f870ba455aeebc85a7bc07 197 Pfam PF13599 Pentapeptide repeats (9 copies) 18 92 1.3E-12 T 12-10-2018 IPR001646 Pentapeptide repeat AFR_05120 1657d56620f870ba455aeebc85a7bc07 197 Pfam PF00805 Pentapeptide repeats (8 copies) 109 145 1.4E-11 T 12-10-2018 IPR001646 Pentapeptide repeat AFR_05120 1657d56620f870ba455aeebc85a7bc07 197 Gene3D G3DSA:2.160.20.100 15 197 5.7E-49 T 12-10-2018 AFR_05120 1657d56620f870ba455aeebc85a7bc07 197 SUPERFAMILY SSF141571 20 194 9.12E-42 T 12-10-2018 AFR_22620 ad5e6776d2adfe7c2f8598d8310dbfa9 266 SUPERFAMILY SSF46955 5 108 3.66E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_22620 ad5e6776d2adfe7c2f8598d8310dbfa9 266 Pfam PF00376 MerR family regulatory protein 6 43 2.0E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22620 ad5e6776d2adfe7c2f8598d8310dbfa9 266 SMART SM00422 5 74 6.5E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22620 ad5e6776d2adfe7c2f8598d8310dbfa9 266 Gene3D G3DSA:1.10.1660.10 1 112 1.4E-24 T 12-10-2018 AFR_22620 ad5e6776d2adfe7c2f8598d8310dbfa9 266 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22620 ad5e6776d2adfe7c2f8598d8310dbfa9 266 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22620 ad5e6776d2adfe7c2f8598d8310dbfa9 266 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_07670 dc180ed910a0b49374375bf68c31ced8 961 SMART SM00316 394 473 3.1E-5 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_07670 dc180ed910a0b49374375bf68c31ced8 961 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 371 770 2.6E-147 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 AFR_07670 dc180ed910a0b49374375bf68c31ced8 961 Gene3D G3DSA:2.40.50.140 389 479 9.1E-26 T 12-10-2018 AFR_07670 dc180ed910a0b49374375bf68c31ced8 961 SUPERFAMILY SSF50249 396 479 4.43E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_07670 dc180ed910a0b49374375bf68c31ced8 961 Pfam PF10150 Ribonuclease E/G family 476 744 3.6E-101 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 AFR_32315 23ef23b389925493208810315d2daab1 207 Pfam PF13460 NAD(P)H-binding 7 196 1.0E-40 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_32315 23ef23b389925493208810315d2daab1 207 SUPERFAMILY SSF51735 2 206 4.08E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_32315 23ef23b389925493208810315d2daab1 207 Gene3D G3DSA:3.40.50.720 1 206 8.0E-42 T 12-10-2018 AFR_11675 69a9f85d072e8b50f98a7eea7c94caa5 150 Gene3D G3DSA:3.40.630.30 1 149 1.0E-16 T 12-10-2018 AFR_11675 69a9f85d072e8b50f98a7eea7c94caa5 150 SUPERFAMILY SSF55729 5 145 3.54E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_11675 69a9f85d072e8b50f98a7eea7c94caa5 150 Pfam PF00583 Acetyltransferase (GNAT) family 12 128 2.9E-9 T 12-10-2018 IPR000182 GNAT domain AFR_08310 07bd845c50eba4733a62032f30f87a2a 304 Pfam PF07690 Major Facilitator Superfamily 2 254 1.8E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_08310 07bd845c50eba4733a62032f30f87a2a 304 Gene3D G3DSA:1.20.1250.20 1 259 4.4E-24 T 12-10-2018 AFR_08310 07bd845c50eba4733a62032f30f87a2a 304 SUPERFAMILY SSF103473 2 256 3.01E-26 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_41990 3676f834cfac19e83fbff500b8fd0efb 398 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 6 368 7.1E-116 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 AFR_41990 3676f834cfac19e83fbff500b8fd0efb 398 Gene3D G3DSA:3.40.50.2000 6 366 6.6E-122 T 12-10-2018 AFR_41990 3676f834cfac19e83fbff500b8fd0efb 398 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 32 368 1.0E-98 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_41990 3676f834cfac19e83fbff500b8fd0efb 398 Gene3D G3DSA:3.40.50.2000 188 356 6.6E-122 T 12-10-2018 AFR_41990 3676f834cfac19e83fbff500b8fd0efb 398 SUPERFAMILY SSF53756 6 369 5.38E-103 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2841 2852 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.300.30 1603 1706 4.2E-35 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.300.30 3091 3190 7.0E-34 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.559.10 2260 2629 1.9E-133 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.559.10 1786 1964 2.8E-50 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1361 1372 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.559.30 943 1178 2.9E-118 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SMART SM00823 Phosphopantetheine attachment site 3202 3271 0.0017 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SMART SM00823 Phosphopantetheine attachment site 1718 1786 0.0024 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SMART SM00823 Phosphopantetheine attachment site 682 751 1.6E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:1.10.1200.10 3191 3274 7.8E-24 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:1.10.1200.10 1707 1784 3.2E-23 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12410 714ba84727142eec349450e7f0c9a814 3293 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1742 1757 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:1.10.1200.10 669 755 5.9E-26 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF47336 676 747 2.09E-19 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF52777 946 1196 1.05E-50 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.559.30 1965 2224 3.9E-77 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF47336 3195 3267 5.23E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_12410 714ba84727142eec349450e7f0c9a814 3293 ProSitePatterns PS00455 Putative AMP-binding domain signature. 326 337 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF52777 762 958 1.06E-46 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.559.30 2439 2693 1.9E-133 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF52777 2440 2686 2.95E-56 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.300.30 568 668 7.6E-35 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00550 Phosphopantetheine attachment site 1720 1780 6.2E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00550 Phosphopantetheine attachment site 684 747 2.6E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00550 Phosphopantetheine attachment site 3204 3264 1.7E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF56801 2677 3214 2.49E-161 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF56801 1173 1731 6.15E-156 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.559.30 74 167 4.1E-8 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.30.559.10 768 1123 2.9E-118 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF52777 1981 2223 9.78E-40 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF13193 AMP-binding enzyme C-terminal domain 1617 1692 4.8E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF13193 AMP-binding enzyme C-terminal domain 581 656 2.2E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF13193 AMP-binding enzyme C-terminal domain 3105 3175 3.3E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00668 Condensation domain 2255 2696 1.6E-78 T 12-10-2018 IPR001242 Condensation domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00668 Condensation domain 767 1193 1.3E-83 T 12-10-2018 IPR001242 Condensation domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00668 Condensation domain 1799 2233 1.1E-67 T 12-10-2018 IPR001242 Condensation domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF52777 1795 1992 3.89E-38 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.40.50.12780 2704 3090 4.8E-146 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.40.50.12780 1199 1602 3.4E-137 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Gene3D G3DSA:3.40.50.12780 173 567 1.9E-136 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2100 2247 2.3E-36 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF52777 2253 2453 1.56E-39 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF56801 142 695 4.32E-153 T 12-10-2018 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00501 AMP-binding enzyme 183 573 1.3E-92 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00501 AMP-binding enzyme 1214 1609 9.1E-93 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 Pfam PF00501 AMP-binding enzyme 2719 3097 4.6E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_12410 714ba84727142eec349450e7f0c9a814 3293 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2738 3121 3.9E-132 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 203 597 4.7E-132 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1234 1633 4.1E-127 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_12410 714ba84727142eec349450e7f0c9a814 3293 ProSitePatterns PS00012 Phosphopantetheine attachment site. 706 721 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFR_12410 714ba84727142eec349450e7f0c9a814 3293 SUPERFAMILY SSF47336 1710 1780 1.7E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_29480 a0d9f43379c201ca3a0d81766169abd3 332 Gene3D G3DSA:2.60.120.10 180 290 7.2E-72 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_29480 a0d9f43379c201ca3a0d81766169abd3 332 Pfam PF02678 Pirin 86 158 1.8E-25 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFR_29480 a0d9f43379c201ca3a0d81766169abd3 332 PIRSF PIRSF006232 49 328 3.9E-72 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFR_29480 a0d9f43379c201ca3a0d81766169abd3 332 Pfam PF05726 Pirin C-terminal cupin domain 213 321 4.1E-19 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 AFR_29480 a0d9f43379c201ca3a0d81766169abd3 332 Gene3D G3DSA:2.60.120.10 74 316 7.2E-72 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_29480 a0d9f43379c201ca3a0d81766169abd3 332 SUPERFAMILY SSF51182 71 325 4.45E-70 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 1.2E-60 T 12-10-2018 AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 186 3.9E-4 T 12-10-2018 AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 SUPERFAMILY SSF51735 6 249 2.65E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.0E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.0E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.0E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.0E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.0E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 Gene3D G3DSA:3.40.50.720 2 250 5.3E-76 T 12-10-2018 AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15750 cca0a198408b3ed10c0cba9aba15a860 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18585 8e09d5e8a0f40fa53a818413951470c4 206 Gene3D G3DSA:3.40.50.1000 39 203 3.1E-31 T 12-10-2018 IPR023214 HAD superfamily AFR_18585 8e09d5e8a0f40fa53a818413951470c4 206 SUPERFAMILY SSF56784 78 192 5.36E-8 T 12-10-2018 IPR036412 HAD-like superfamily AFR_18585 8e09d5e8a0f40fa53a818413951470c4 206 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 99 202 3.4E-14 T 12-10-2018 IPR005519 Acid phosphatase, class B-like AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 Gene3D G3DSA:2.40.30.10 229 322 5.0E-26 T 12-10-2018 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 72 87 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 SUPERFAMILY SSF50465 325 429 4.27E-32 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 10 432 46.467 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 SUPERFAMILY SSF50447 234 322 9.77E-21 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 Gene3D G3DSA:3.40.50.300 2 228 1.5E-65 T 12-10-2018 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 Gene3D G3DSA:2.40.30.10 323 430 4.8E-36 T 12-10-2018 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 Pfam PF00009 Elongation factor Tu GTP binding domain 19 202 7.3E-41 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 19 428 5.6E-172 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 SUPERFAMILY SSF52540 18 224 9.26E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 PRINTS PR00315 GTP-binding elongation factor signature 99 109 2.9E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 PRINTS PR00315 GTP-binding elongation factor signature 79 87 2.9E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 PRINTS PR00315 GTP-binding elongation factor signature 115 126 2.9E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 PRINTS PR00315 GTP-binding elongation factor signature 152 161 2.9E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_39690 08d84d12215cb6d6572f22fcc357e755 432 PRINTS PR00315 GTP-binding elongation factor signature 20 33 2.9E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_01470 5b1541a17c1bfb6eeaabb409909366c3 389 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 7 371 47.259 T 12-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFR_01470 5b1541a17c1bfb6eeaabb409909366c3 389 Pfam PF04055 Radical SAM superfamily 61 229 6.2E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_01470 5b1541a17c1bfb6eeaabb409909366c3 389 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 368 3.4E-156 T 12-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFR_01470 5b1541a17c1bfb6eeaabb409909366c3 389 PIRSF PIRSF004762 2 379 1.5E-98 T 12-10-2018 AFR_01470 5b1541a17c1bfb6eeaabb409909366c3 389 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 6.0E-95 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AFR_01470 5b1541a17c1bfb6eeaabb409909366c3 389 Gene3D G3DSA:3.20.20.70 3 366 5.0E-49 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_01470 5b1541a17c1bfb6eeaabb409909366c3 389 SUPERFAMILY SSF102114 16 361 6.41E-41 T 12-10-2018 AFR_09605 135d8c223db64821e7ab89070a25b254 78 Pfam PF13396 Phospholipase_D-nuclease N-terminal 33 74 1.9E-7 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 SMART SM01016 1 82 1.4E-18 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 SUPERFAMILY SSF52374 105 432 1.8E-75 T 12-10-2018 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 SUPERFAMILY SSF47323 437 552 1.57E-26 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 SMART SM00836 442 552 3.3E-29 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 Gene3D G3DSA:3.30.1360.70 1 101 3.8E-17 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 SUPERFAMILY SSF55190 1 93 1.15E-11 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 Gene3D G3DSA:1.10.730.10 435 552 5.4E-27 T 12-10-2018 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 294 315 4.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 141 4.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 149 162 4.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 110 125 4.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 24 552 8.0E-122 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 Pfam PF05746 DALR anticodon binding domain 442 552 4.0E-25 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 Hamap MF_00123 Arginine--tRNA ligase [argS]. 1 552 23.325 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 118 129 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 82 9.8E-13 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 Pfam PF00750 tRNA synthetases class I (R) 105 427 3.4E-96 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AFR_08510 de2e6d1f1080fc0e730dd604f8ce50f0 552 Gene3D G3DSA:3.40.50.620 105 434 8.9E-90 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_28310 75e584fcd79c1a3223f7730bd391cb0c 536 Gene3D G3DSA:2.10.10.20 478 524 3.4E-7 T 12-10-2018 AFR_28310 75e584fcd79c1a3223f7730bd391cb0c 536 SUPERFAMILY SSF51055 477 526 2.09E-9 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_28310 75e584fcd79c1a3223f7730bd391cb0c 536 Gene3D G3DSA:2.10.10.20 394 464 1.9E-6 T 12-10-2018 AFR_28310 75e584fcd79c1a3223f7730bd391cb0c 536 SUPERFAMILY SSF51445 72 350 7.26E-20 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_28310 75e584fcd79c1a3223f7730bd391cb0c 536 Gene3D G3DSA:3.20.20.80 62 393 4.0E-91 T 12-10-2018 AFR_28310 75e584fcd79c1a3223f7730bd391cb0c 536 Pfam PF00704 Glycosyl hydrolases family 18 90 267 1.3E-8 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_28310 75e584fcd79c1a3223f7730bd391cb0c 536 SUPERFAMILY SSF51055 407 459 1.03E-7 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 Gene3D G3DSA:3.40.47.10 6 259 1.2E-136 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 Pfam PF00108 Thiolase, N-terminal domain 5 244 4.8E-68 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 SUPERFAMILY SSF53901 3 253 1.35E-72 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 374 7.6E-130 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 ProSitePatterns PS00737 Thiolases signature 2. 322 338 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 PIRSF PIRSF000429 1 376 2.1E-120 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 Gene3D G3DSA:3.40.47.10 127 373 1.2E-136 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 Pfam PF02803 Thiolase, C-terminal domain 254 374 1.9E-40 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFR_42355 49b65939049d859a513a99ecdffdcd94 376 SUPERFAMILY SSF53901 254 375 1.68E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_10635 3b94ea79208e62470c676139cbb5cc54 379 SUPERFAMILY SSF51569 7 362 7.57E-73 T 12-10-2018 AFR_10635 3b94ea79208e62470c676139cbb5cc54 379 Hamap MF_00493 Transaldolase [tal]. 1 370 154.865 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFR_10635 3b94ea79208e62470c676139cbb5cc54 379 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFR_10635 3b94ea79208e62470c676139cbb5cc54 379 Gene3D G3DSA:3.20.20.70 2 365 5.7E-154 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10635 3b94ea79208e62470c676139cbb5cc54 379 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 15 359 2.8E-78 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFR_10635 3b94ea79208e62470c676139cbb5cc54 379 TIGRFAM TIGR00876 tal_mycobact: transaldolase 11 358 2.5E-134 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFR_10635 3b94ea79208e62470c676139cbb5cc54 379 PIRSF PIRSF036915 1 371 3.0E-165 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFR_02610 5bfb36d9cfd0c57943a810a2c6437643 627 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 37 140 4.0E-5 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal AFR_02610 5bfb36d9cfd0c57943a810a2c6437643 627 SUPERFAMILY SSF53448 242 481 1.5E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02610 5bfb36d9cfd0c57943a810a2c6437643 627 Pfam PF13641 Glycosyltransferase like family 2 239 465 2.3E-25 T 12-10-2018 AFR_02610 5bfb36d9cfd0c57943a810a2c6437643 627 Gene3D G3DSA:3.90.550.10 230 447 3.9E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02610 5bfb36d9cfd0c57943a810a2c6437643 627 SUPERFAMILY SSF160246 3 137 1.52E-14 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily AFR_08335 ff39436b15e7e0b6c3f15877a89832f5 126 SMART SM00226 1 124 1.2E-51 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFR_08335 ff39436b15e7e0b6c3f15877a89832f5 126 Gene3D G3DSA:3.40.50.2300 1 126 8.0E-53 T 12-10-2018 AFR_08335 ff39436b15e7e0b6c3f15877a89832f5 126 SUPERFAMILY SSF52788 1 122 4.45E-38 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFR_08335 ff39436b15e7e0b6c3f15877a89832f5 126 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 1 122 7.7E-26 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFR_00195 108d436f880a2db6e9c7fb535216290e 385 PIRSF PIRSF016578 243 383 2.2E-7 T 12-10-2018 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 PIRSF PIRSF016578 131 239 0.2 T 12-10-2018 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 PIRSF PIRSF016578 5 98 0.0024 T 12-10-2018 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 Gene3D G3DSA:1.20.140.10 240 383 1.8E-49 T 12-10-2018 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 Gene3D G3DSA:1.10.540.10 1 120 5.3E-40 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 7.6E-48 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 2.6E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 Gene3D G3DSA:2.40.110.10 122 239 9.6E-35 T 12-10-2018 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 223 9.0E-21 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 SUPERFAMILY SSF47203 233 383 2.9E-51 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 SUPERFAMILY SSF56645 2 248 1.26E-78 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_00195 108d436f880a2db6e9c7fb535216290e 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 Gene3D G3DSA:3.40.50.720 1 199 3.9E-68 T 12-10-2018 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 SUPERFAMILY SSF52413 324 449 1.96E-35 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 SUPERFAMILY SSF48179 221 315 1.97E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 337 439 3.7E-30 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 187 7.3E-58 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 SUPERFAMILY SSF51735 1 198 1.14E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 PIRSF PIRSF500134 1 455 1.2E-155 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 222 313 3.7E-35 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 SMART SM00984 336 439 1.4E-45 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 Gene3D G3DSA:1.20.5.100 220 251 2.2E-14 T 12-10-2018 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 434 3.3E-128 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 Gene3D G3DSA:3.40.50.720 252 455 6.1E-70 T 12-10-2018 AFR_27345 b3926b04ab89e929f03ff92da30665c5 455 PIRSF PIRSF000124 1 454 1.3E-127 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_17355 5b2808f0a4e40c82310d763c0482e679 331 Pfam PF00535 Glycosyl transferase family 2 38 157 8.6E-14 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_17355 5b2808f0a4e40c82310d763c0482e679 331 SUPERFAMILY SSF53448 37 283 5.63E-58 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_17355 5b2808f0a4e40c82310d763c0482e679 331 Gene3D G3DSA:3.90.550.10 4 325 2.9E-109 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05530 5c56a0c624e58c0a4567eb629a1489ba 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 286 3.2E-149 T 12-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 AFR_05530 5c56a0c624e58c0a4567eb629a1489ba 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 153 1.7E-23 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 AFR_05530 5c56a0c624e58c0a4567eb629a1489ba 293 Gene3D G3DSA:3.40.50.10320 1 292 9.7E-77 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_05530 5c56a0c624e58c0a4567eb629a1489ba 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 287 53.91 T 12-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 AFR_05530 5c56a0c624e58c0a4567eb629a1489ba 293 SUPERFAMILY SSF102588 4 287 3.79E-74 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 Pfam PF00990 Diguanylate cyclase, GGDEF domain 570 729 2.9E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 Gene3D G3DSA:3.20.20.450 748 998 5.4E-100 T 12-10-2018 IPR035919 EAL domain superfamily AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 SMART SM00091 447 511 3.8E-6 T 12-10-2018 IPR000014 PAS domain AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 SMART SM00052 745 993 7.6E-116 T 12-10-2018 IPR001633 EAL domain AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 Gene3D G3DSA:3.30.70.270 569 747 6.4E-51 T 12-10-2018 AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 SUPERFAMILY SSF55073 575 736 4.94E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 566 731 3.4E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 445 566 1.1E-13 T 12-10-2018 IPR000014 PAS domain AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 SMART SM00267 559 735 2.9E-54 T 12-10-2018 IPR000160 GGDEF domain AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 Pfam PF00563 EAL domain 752 988 3.4E-78 T 12-10-2018 IPR001633 EAL domain AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 Pfam PF00989 PAS fold 449 556 2.0E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 SUPERFAMILY SSF141868 752 997 5.23E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 Gene3D G3DSA:3.30.450.20 446 568 4.6E-15 T 12-10-2018 AFR_24520 e26c0666e2dee2aba0c8901fde39b4e0 1005 SUPERFAMILY SSF55785 442 557 9.07E-14 T 12-10-2018 IPR035965 PAS domain superfamily AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.2E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.2E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.2E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.2E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.2E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.2E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 Gene3D G3DSA:3.40.50.720 1 251 1.5E-67 T 12-10-2018 AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 249 1.7E-47 T 12-10-2018 AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 SUPERFAMILY SSF51735 3 249 2.97E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 4.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 4.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11940 f52e2cfd79dfda0b30e833f260f4369d 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_25895 79e3878322ae86d142e98f9a732e7262 528 Gene3D G3DSA:1.10.150.20 310 360 1.4E-7 T 12-10-2018 AFR_25895 79e3878322ae86d142e98f9a732e7262 528 SMART SM00278 315 334 0.029 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_25895 79e3878322ae86d142e98f9a732e7262 528 SMART SM00278 460 479 0.1 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_25895 79e3878322ae86d142e98f9a732e7262 528 Gene3D G3DSA:1.10.150.20 459 519 9.8E-9 T 12-10-2018 AFR_25895 79e3878322ae86d142e98f9a732e7262 528 Pfam PF14520 Helix-hairpin-helix domain 316 352 5.9E-7 T 12-10-2018 AFR_25895 79e3878322ae86d142e98f9a732e7262 528 Pfam PF14520 Helix-hairpin-helix domain 460 497 5.1E-8 T 12-10-2018 AFR_19755 1f81c0097cf18bf06378d2a17653b1b4 294 Pfam PF01497 Periplasmic binding protein 4 249 1.4E-12 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFR_19755 1f81c0097cf18bf06378d2a17653b1b4 294 SUPERFAMILY SSF53807 2 279 1.96E-39 T 12-10-2018 AFR_19755 1f81c0097cf18bf06378d2a17653b1b4 294 Gene3D G3DSA:3.40.50.1980 1 150 1.6E-24 T 12-10-2018 AFR_19755 1f81c0097cf18bf06378d2a17653b1b4 294 Gene3D G3DSA:3.40.50.1980 153 278 1.1E-24 T 12-10-2018 AFR_39295 35d992a6eb2d13098e04ecd8c7eef4eb 263 Pfam PF13490 Putative zinc-finger 192 226 4.5E-6 T 12-10-2018 IPR027383 Putative zinc-finger AFR_39295 35d992a6eb2d13098e04ecd8c7eef4eb 263 SUPERFAMILY SSF88946 6 110 2.71E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_39295 35d992a6eb2d13098e04ecd8c7eef4eb 263 Gene3D G3DSA:1.10.10.10 125 181 2.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39295 35d992a6eb2d13098e04ecd8c7eef4eb 263 Pfam PF04542 Sigma-70 region 2 28 96 1.2E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_39295 35d992a6eb2d13098e04ecd8c7eef4eb 263 SUPERFAMILY SSF88659 115 178 6.35E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_39295 35d992a6eb2d13098e04ecd8c7eef4eb 263 Gene3D G3DSA:1.10.1740.10 5 121 1.7E-18 T 12-10-2018 AFR_39295 35d992a6eb2d13098e04ecd8c7eef4eb 263 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 177 8.9E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_22610 fb65225c91ded247d1acad990c39c285 369 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 74 269 3.8E-31 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_22610 fb65225c91ded247d1acad990c39c285 369 Gene3D G3DSA:1.10.260.150 38 356 1.2E-56 T 12-10-2018 AFR_34445 42284649d732f0d9276894e5d633fcec 311 SUPERFAMILY SSF52540 32 249 2.08E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34445 42284649d732f0d9276894e5d633fcec 311 Gene3D G3DSA:3.40.50.300 32 276 1.9E-55 T 12-10-2018 AFR_34445 42284649d732f0d9276894e5d633fcec 311 Pfam PF00005 ABC transporter 50 197 1.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_34445 42284649d732f0d9276894e5d633fcec 311 SMART SM00382 59 246 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41260 c6aee8701399dba1999554948e04b531 358 SMART SM00028 151 184 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_41260 c6aee8701399dba1999554948e04b531 358 SMART SM00028 15 48 87.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_41260 c6aee8701399dba1999554948e04b531 358 SMART SM00028 49 82 120.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_41260 c6aee8701399dba1999554948e04b531 358 SUPERFAMILY SSF48452 15 186 1.52E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41260 c6aee8701399dba1999554948e04b531 358 Gene3D G3DSA:1.25.40.10 6 221 2.1E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_36125 30cb53cd5fe28bda1141cb4a810049b7 344 Gene3D G3DSA:3.20.20.30 22 334 3.8E-58 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_36125 30cb53cd5fe28bda1141cb4a810049b7 344 SUPERFAMILY SSF51679 24 321 2.88E-49 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_36125 30cb53cd5fe28bda1141cb4a810049b7 344 TIGRFAM TIGR03841 F420_Rv3093c: probable F420-dependent oxidoreductase, Rv3093c family 28 321 1.8E-99 T 12-10-2018 IPR022526 F420-dependent oxidoreductase, Rv3093c AFR_36125 30cb53cd5fe28bda1141cb4a810049b7 344 Pfam PF00296 Luciferase-like monooxygenase 21 313 1.0E-50 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_19890 ddc65ac1253a6ed00afaed7158755381 192 SUPERFAMILY SSF48498 84 183 2.08E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_19890 ddc65ac1253a6ed00afaed7158755381 192 Gene3D G3DSA:1.10.10.60 6 52 3.4E-20 T 12-10-2018 AFR_19890 ddc65ac1253a6ed00afaed7158755381 192 Gene3D G3DSA:1.10.357.10 53 183 7.2E-34 T 12-10-2018 AFR_19890 ddc65ac1253a6ed00afaed7158755381 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 6.9E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19890 ddc65ac1253a6ed00afaed7158755381 192 SUPERFAMILY SSF46689 2 75 8.21E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19890 ddc65ac1253a6ed00afaed7158755381 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19890 ddc65ac1253a6ed00afaed7158755381 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 SMART SM00866 82 221 3.6E-36 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 Pfam PF07702 UTRA domain 86 221 1.9E-38 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 SMART SM00345 7 64 1.0E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 Gene3D G3DSA:3.40.1410.10 82 227 1.7E-41 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 2.7E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 2.7E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 Gene3D G3DSA:1.10.10.10 3 73 1.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 SUPERFAMILY SSF46785 6 72 2.42E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 SUPERFAMILY SSF64288 52 227 2.67E-42 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_04295 eb31cabeac4369d6b91161ffa1f558e4 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 63 1.8E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_41780 24d41fc8dd403a0a4c5aae0daa06c9d3 354 SUPERFAMILY SSF52540 21 270 1.97E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41780 24d41fc8dd403a0a4c5aae0daa06c9d3 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 337 3.1E-21 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_41780 24d41fc8dd403a0a4c5aae0daa06c9d3 354 Gene3D G3DSA:3.40.50.300 19 351 9.2E-95 T 12-10-2018 AFR_41780 24d41fc8dd403a0a4c5aae0daa06c9d3 354 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_41780 24d41fc8dd403a0a4c5aae0daa06c9d3 354 Pfam PF00005 ABC transporter 41 199 6.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_41780 24d41fc8dd403a0a4c5aae0daa06c9d3 354 SMART SM00382 49 249 3.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41780 24d41fc8dd403a0a4c5aae0daa06c9d3 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 312 1.1E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_42015 b93ec4f1255a3cfd9bf964e541b704d3 471 Pfam PF00553 Cellulose binding domain 40 136 5.6E-26 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_42015 b93ec4f1255a3cfd9bf964e541b704d3 471 Pfam PF00704 Glycosyl hydrolases family 18 232 409 1.3E-10 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_42015 b93ec4f1255a3cfd9bf964e541b704d3 471 SUPERFAMILY SSF49384 35 136 1.33E-28 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_42015 b93ec4f1255a3cfd9bf964e541b704d3 471 Gene3D G3DSA:2.60.40.290 37 140 1.9E-30 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_42015 b93ec4f1255a3cfd9bf964e541b704d3 471 SUPERFAMILY SSF51445 183 443 1.01E-23 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_42015 b93ec4f1255a3cfd9bf964e541b704d3 471 Gene3D G3DSA:3.20.20.80 176 471 9.6E-99 T 12-10-2018 AFR_42015 b93ec4f1255a3cfd9bf964e541b704d3 471 SMART SM00637 39 136 1.3E-35 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Gene3D G3DSA:2.130.10.30 3 173 1.2E-43 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Gene3D G3DSA:2.130.10.30 328 371 1.5E-7 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 89 135 1.2E-10 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 341 368 1.2E-5 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 335 356 9.7E-13 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 41 57 9.7E-13 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 92 108 9.7E-13 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 177 193 9.7E-13 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 140 156 9.7E-13 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 193 207 9.7E-13 T 12-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 227 253 3.8E-7 T 12-10-2018 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 276 302 1.7E-5 T 12-10-2018 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 174 203 3.8E-9 T 12-10-2018 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 23 51 4.9E-9 T 12-10-2018 AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 SUPERFAMILY SSF50985 22 160 6.28E-40 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 Gene3D G3DSA:2.130.10.30 174 327 5.6E-37 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_14925 59d50ef15eb76e7ce8de92e39b620839 371 SUPERFAMILY SSF50985 120 369 6.02E-61 T 12-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II AFR_02740 abe8ea6a1608dba81ef6cf04a6ba8ac9 171 Gene3D G3DSA:2.60.120.10 6 168 7.8E-43 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_02740 abe8ea6a1608dba81ef6cf04a6ba8ac9 171 SUPERFAMILY SSF51182 8 141 1.17E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_02740 abe8ea6a1608dba81ef6cf04a6ba8ac9 171 Pfam PF07883 Cupin domain 51 116 2.4E-18 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_07220 9f01870704fac8576a9154f7a55ef7c7 346 Pfam PF01471 Putative peptidoglycan binding domain 118 168 3.0E-10 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_07220 9f01870704fac8576a9154f7a55ef7c7 346 Pfam PF13437 HlyD family secretion protein 170 259 6.3E-7 T 12-10-2018 AFR_07220 9f01870704fac8576a9154f7a55ef7c7 346 Gene3D G3DSA:2.40.420.20 270 344 6.2E-10 T 12-10-2018 AFR_07220 9f01870704fac8576a9154f7a55ef7c7 346 Gene3D G3DSA:1.10.101.10 104 172 1.8E-9 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_07220 9f01870704fac8576a9154f7a55ef7c7 346 SUPERFAMILY SSF47090 106 168 3.3E-13 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_34645 45123470e815f1b2f7923ada43d0ab44 242 SMART SM00849 14 217 1.5E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_34645 45123470e815f1b2f7923ada43d0ab44 242 Gene3D G3DSA:3.60.15.10 1 234 5.0E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_34645 45123470e815f1b2f7923ada43d0ab44 242 Pfam PF00753 Metallo-beta-lactamase superfamily 12 217 3.5E-26 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_34645 45123470e815f1b2f7923ada43d0ab44 242 SUPERFAMILY SSF56281 2 233 1.29E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 Gene3D G3DSA:1.10.287.950 205 520 1.5E-62 T 12-10-2018 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 SUPERFAMILY SSF58104 226 518 1.83E-60 T 12-10-2018 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 491 6.1E-31 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 SMART SM00283 265 519 2.8E-47 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 6.4E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 6.4E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 6.4E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 9 34 6.4E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 282 311 6.4E-23 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 SMART SM00304 205 257 5.9E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 Pfam PF00672 HAMP domain 205 253 9.9E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_06470 8b9e9649b58c1b8d0f53ebf0efd262f5 520 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 177 9.0E-25 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_10180 81210ecc3caee9a6830612ab114e83b6 155 Gene3D G3DSA:2.30.110.10 8 152 1.9E-24 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_10180 81210ecc3caee9a6830612ab114e83b6 155 SUPERFAMILY SSF50475 28 137 6.17E-9 T 12-10-2018 AFR_10180 81210ecc3caee9a6830612ab114e83b6 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 28 87 1.8E-4 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 67 594 5.2E-31 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 62 347 1.3E-66 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 SUPERFAMILY SSF49785 434 611 2.89E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 SMART SM00939 362 610 1.5E-36 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 375 600 6.6E-33 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 Gene3D G3DSA:3.40.50.1820 46 264 1.5E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 Gene3D G3DSA:3.40.50.1820 283 422 3.6E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 SUPERFAMILY SSF53474 39 386 1.94E-75 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 66 75 6.3E-14 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 80 96 6.3E-14 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 48 58 6.3E-14 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_18185 ce6a920d0eaa72a8c1c934eea207d151 612 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 576 591 6.3E-14 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.40.10.500 235 331 1.8E-14 T 12-10-2018 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 3278 3449 3.0E-19 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 861 1049 3.02E-27 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF63829 134 381 7.19E-20 T 12-10-2018 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 1780 1897 3.24E-15 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2310 2383 4.4E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2039 2112 1.3E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1687 1762 4.3E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 864 945 2.0E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 482 564 1.1E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3102 3183 5.6E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2129 2201 4.2E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1245 1320 1.1E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1775 1850 1.2E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2662 2735 3.2E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2487 2560 1.3E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1055 1138 4.4E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3455 3530 4.6E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2216 2297 2.8E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 672 754 5.5E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3014 3089 5.2E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1333 1407 1.8E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1951 2026 6.5E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2575 2649 3.7E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 387 469 2.4E-13 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3811 3882 1.0E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3367 3442 1.1E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3196 3268 5.2E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1599 1674 3.6E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2843 2913 1.8E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 960 1041 1.8E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1151 1232 2.4E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1864 1937 7.1E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3720 3798 1.7E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1510 1583 3.4E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2926 2999 6.5E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 769 849 3.8E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2399 2472 3.0E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 578 659 1.4E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 2747 2828 3.0E-13 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 1422 1496 1.1E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Pfam PF00041 Fibronectin type III domain 3634 3707 4.9E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 1241 1415 3.33E-26 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3807 3894 3.5E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 2839 2961 8.18E-14 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3191 3276 5.5E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 3625 3805 1.91E-25 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 2659 2838 3.18E-28 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 3452 3622 4.95E-22 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 386 466 2.0E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2840 2910 2.6E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3100 3180 9.4E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3453 3527 3.6E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1685 1759 5.5E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3718 3795 5.1E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3626 3706 2.0E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2214 2294 1.7E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3809 3884 3.6E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1332 1406 3.1E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1420 1494 1.9E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2126 2200 1.9E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2308 2382 9.5E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2746 2825 1.4E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3195 3265 6.9E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1597 1671 1.7E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2573 2646 5.1E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 480 562 5.6E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2924 2998 6.9E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1773 1847 2.7E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 767 847 1.4E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1053 1135 6.9E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2037 2111 1.8E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2397 2471 1.4E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 958 1038 2.7E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3012 3086 3.7E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1149 1229 4.3E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1861 1934 7.2E-10 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 862 944 9.2E-13 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 576 656 7.8E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1508 1582 2.3E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3279 3352 1.6E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2485 2559 2.1E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1949 2023 2.2E-13 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 1243 1317 1.9E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 671 753 1.4E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3542 3612 6.1E-8 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 2660 2732 1.4E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SMART SM00060 3365 3439 5.4E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 1596 1770 2.65E-27 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 760 853 1.95E-14 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 381 480 2.7E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2395 2484 2.2E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 481 576 3.2E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3453 3542 5.2E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3543 3627 9.0E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2485 2571 1.1E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2661 2746 1.7E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1333 1420 1.4E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1241 1332 5.9E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1685 1776 1.0E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2925 3011 1.1E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1777 1860 2.5E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2572 2660 9.5E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 669 766 2.5E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 859 958 1.4E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3362 3452 2.2E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3717 3806 3.5E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2841 2924 2.9E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1050 1150 1.3E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2312 2394 6.5E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1421 1508 9.2E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1947 2036 7.1E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1861 1946 5.8E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2747 2840 9.4E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2217 2311 3.0E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1598 1684 3.0E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3628 3716 4.1E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1509 1597 1.4E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2037 2123 1.9E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3012 3100 1.0E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 2124 2216 6.9E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 2393 2480 1.97E-12 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3277 3361 5.4E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 1151 1240 6.2E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 959 1049 5.8E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 767 858 2.7E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 577 668 3.1E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.60.40.10 3101 3190 4.5E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 3793 3905 2.67E-14 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 2484 2656 6.81E-28 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 1053 1238 3.72E-26 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 2923 3096 1.11E-25 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 Gene3D G3DSA:2.120.10.30 63 206 3.2E-20 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 385 571 4.49E-26 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 2223 2397 6.01E-27 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 1419 1597 3.75E-27 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 3099 3274 1.44E-21 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 575 756 1.15E-26 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 1860 2033 9.02E-30 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_22960 02e2c8c55b0af8d09c052855f36ae0b2 4050 SUPERFAMILY SSF49265 2036 2208 8.11E-25 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_07485 9b937c1a8fb461046ddd6b6a2e1163d2 305 SUPERFAMILY SSF53474 51 301 3.21E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_07485 9b937c1a8fb461046ddd6b6a2e1163d2 305 Gene3D G3DSA:3.40.50.1820 8 301 8.8E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_07485 9b937c1a8fb461046ddd6b6a2e1163d2 305 Pfam PF07859 alpha/beta hydrolase fold 75 279 1.4E-69 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 SUPERFAMILY SSF47323 618 825 3.55E-35 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 Gene3D G3DSA:1.10.730.10 10 775 2.5E-187 T 12-10-2018 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 Hamap MF_02005 Valine--tRNA ligase [valS]. 1 819 27.005 T 12-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 SUPERFAMILY SSF52374 1 609 1.96E-108 T 12-10-2018 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 55 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 SUPERFAMILY SSF50677 212 352 1.83E-27 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 Gene3D G3DSA:3.40.50.620 21 567 2.5E-187 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 PRINTS PR00986 Valyl-tRNA synthetase signature 487 508 1.5E-11 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 PRINTS PR00986 Valyl-tRNA synthetase signature 367 380 1.5E-11 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 PRINTS PR00986 Valyl-tRNA synthetase signature 518 536 1.5E-11 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 PRINTS PR00986 Valyl-tRNA synthetase signature 37 48 1.5E-11 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 Pfam PF08264 Anticodon-binding domain of tRNA 644 786 6.3E-24 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 Gene3D G3DSA:3.90.740.10 193 363 2.5E-187 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 248 3.9E-35 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_39175 4d668b90f77f2e9c72e4eb9048f0b0a6 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 251 604 1.3E-57 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 SUPERFAMILY SSF51120 270 376 1.92E-15 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Gene3D G3DSA:2.150.10.10 252 296 2.6E-11 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Gene3D G3DSA:2.150.10.10 30 164 1.0E-11 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Gene3D G3DSA:2.150.10.10 297 420 2.0E-11 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 SUPERFAMILY SSF51120 168 291 1.47E-25 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Gene3D G3DSA:2.150.10.10 205 251 5.6E-11 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Gene3D G3DSA:2.150.10.10 165 204 1.2E-8 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 PRINTS PR00313 NodO calcium binding signature 142 150 2.0E-10 T 12-10-2018 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 PRINTS PR00313 NodO calcium binding signature 250 259 2.0E-10 T 12-10-2018 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 PRINTS PR00313 NodO calcium binding signature 205 213 2.0E-10 T 12-10-2018 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 PRINTS PR00313 NodO calcium binding signature 121 132 2.0E-10 T 12-10-2018 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 204 221 0.017 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 321 338 0.14 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 124 140 0.21 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 222 239 0.0011 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 304 320 0.0072 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 168 183 0.017 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 142 158 0.016 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 276 293 0.022 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 258 274 0.041 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 241 257 0.039 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 186 202 0.0039 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_01010 d9b75b0c49dae9063d187d504e8dc46b 422 SUPERFAMILY SSF51120 104 166 1.23E-12 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 Gene3D G3DSA:1.10.230.10 208 308 2.2E-68 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 Gene3D G3DSA:1.10.580.10 1 62 3.2E-10 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 Gene3D G3DSA:1.10.580.10 109 334 2.2E-68 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 PRINTS PR00143 Citrate synthase signature 182 210 1.0E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 PRINTS PR00143 Citrate synthase signature 314 328 1.0E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 PRINTS PR00143 Citrate synthase signature 235 255 1.0E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 PRINTS PR00143 Citrate synthase signature 294 310 1.0E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 PRINTS PR00143 Citrate synthase signature 160 175 1.0E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 5.6E-85 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_16665 310bcd4be996ecac7e6f592f0f3279b5 370 SUPERFAMILY SSF48256 2 354 7.46E-93 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFR_31980 b1eac155b385535bbf82ab2972e18660 503 Pfam PF00990 Diguanylate cyclase, GGDEF domain 345 495 8.1E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_31980 b1eac155b385535bbf82ab2972e18660 503 SMART SM00267 334 501 1.0E-60 T 12-10-2018 IPR000160 GGDEF domain AFR_31980 b1eac155b385535bbf82ab2972e18660 503 Gene3D G3DSA:3.30.70.270 339 501 3.8E-55 T 12-10-2018 AFR_31980 b1eac155b385535bbf82ab2972e18660 503 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 341 500 8.1E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_31980 b1eac155b385535bbf82ab2972e18660 503 SUPERFAMILY SSF55073 350 500 2.12E-46 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_37145 10c092a844c9b40e41c80b43217eed5e 949 SUPERFAMILY SSF52768 3 296 3.42E-48 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily AFR_37145 10c092a844c9b40e41c80b43217eed5e 949 Pfam PF00491 Arginase family 4 296 6.3E-30 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_37145 10c092a844c9b40e41c80b43217eed5e 949 Gene3D G3DSA:3.40.800.10 2 300 7.7E-59 T 12-10-2018 AFR_37145 10c092a844c9b40e41c80b43217eed5e 949 PRINTS PR00116 Arginase signature 225 254 1.2E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_37145 10c092a844c9b40e41c80b43217eed5e 949 PRINTS PR00116 Arginase signature 96 111 1.2E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_05370 6fe1c4f223367718ec3389aa7b2232f1 231 Pfam PF13559 Domain of unknown function (DUF4129) 150 219 7.4E-10 T 12-10-2018 IPR025403 Domain of unknown function DUF4129 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 Gene3D G3DSA:3.40.50.1980 27 198 1.2E-39 T 12-10-2018 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 Gene3D G3DSA:3.40.50.1980 199 309 1.9E-38 T 12-10-2018 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00691 Adhesin B signature 35 56 6.0E-8 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00691 Adhesin B signature 285 303 6.0E-8 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00691 Adhesin B signature 140 159 6.0E-8 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00691 Adhesin B signature 196 213 6.0E-8 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00691 Adhesin B signature 60 78 6.0E-8 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 Pfam PF01297 Zinc-uptake complex component A periplasmic 38 304 7.0E-69 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00690 Adhesin family signature 35 53 3.2E-8 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00690 Adhesin family signature 196 217 3.2E-8 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00690 Adhesin family signature 66 79 3.2E-8 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 PRINTS PR00690 Adhesin family signature 249 267 3.2E-8 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_08090 21555ddc1efde0ea2717822471a7efcc 310 SUPERFAMILY SSF53807 31 307 1.52E-71 T 12-10-2018 AFR_41020 8333baecb2672bb50d140f7888694f15 307 SUPERFAMILY SSF53697 21 304 1.87E-37 T 12-10-2018 AFR_41020 8333baecb2672bb50d140f7888694f15 307 Gene3D G3DSA:3.40.50.10490 4 151 1.1E-18 T 12-10-2018 AFR_41020 8333baecb2672bb50d140f7888694f15 307 Gene3D G3DSA:3.40.50.10490 264 306 3.0E-5 T 12-10-2018 AFR_41020 8333baecb2672bb50d140f7888694f15 307 Gene3D G3DSA:3.40.50.10490 170 247 6.6E-13 T 12-10-2018 AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 SUPERFAMILY SSF55073 343 494 3.37E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 Gene3D G3DSA:3.20.20.450 507 766 1.4E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 Gene3D G3DSA:3.30.70.270 332 506 1.2E-50 T 12-10-2018 AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 Pfam PF00990 Diguanylate cyclase, GGDEF domain 338 487 3.6E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 SMART SM00052 503 752 1.2E-97 T 12-10-2018 IPR001633 EAL domain AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 SUPERFAMILY SSF141868 509 759 2.35E-79 T 12-10-2018 IPR035919 EAL domain superfamily AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 Pfam PF00563 EAL domain 510 747 9.0E-69 T 12-10-2018 IPR001633 EAL domain AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 334 489 3.7E-32 T 12-10-2018 IPR000160 GGDEF domain AFR_24825 96177ff70a2ec85275e4c753ce7590be 767 SMART SM00267 327 493 1.7E-48 T 12-10-2018 IPR000160 GGDEF domain AFR_35270 b1566f4762d783376cb55e3cf92961f3 219 SUPERFAMILY SSF116726 128 207 1.83E-5 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_35270 b1566f4762d783376cb55e3cf92961f3 219 Pfam PF02254 TrkA-N domain 1 114 2.3E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFR_35270 b1566f4762d783376cb55e3cf92961f3 219 Pfam PF02080 TrkA-C domain 152 209 9.6E-7 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFR_35270 b1566f4762d783376cb55e3cf92961f3 219 SUPERFAMILY SSF51735 1 138 7.58E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35270 b1566f4762d783376cb55e3cf92961f3 219 Gene3D G3DSA:3.30.70.1450 132 211 2.2E-5 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_35270 b1566f4762d783376cb55e3cf92961f3 219 Gene3D G3DSA:3.40.50.720 1 131 2.7E-33 T 12-10-2018 AFR_41170 10ed9ad8317f4eee257aeec7b6691d60 743 Pfam PF02687 FtsX-like permease family 651 740 1.4E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_41170 10ed9ad8317f4eee257aeec7b6691d60 743 Pfam PF02687 FtsX-like permease family 249 343 1.4E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 Gene3D G3DSA:2.40.30.10 276 372 3.3E-11 T 12-10-2018 AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 SUPERFAMILY SSF63380 279 375 1.42E-15 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 Pfam PF08022 FAD-binding domain 285 358 1.1E-8 T 12-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 Gene3D G3DSA:3.40.50.80 375 502 6.8E-24 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 Pfam PF01794 Ferric reductase like transmembrane component 112 234 6.6E-15 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 PRINTS PR00410 Phenol hydroxylase reductase family signature 369 378 3.4E-11 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 PRINTS PR00410 Phenol hydroxylase reductase family signature 468 476 3.4E-11 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 PRINTS PR00410 Phenol hydroxylase reductase family signature 385 404 3.4E-11 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 SUPERFAMILY SSF52343 365 498 1.07E-27 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_34010 638db60d82fdf7ebf15145e61d83f0ae 502 Pfam PF00175 Oxidoreductase NAD-binding domain 386 481 3.4E-8 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 SMART SM00421 847 904 5.2E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 Pfam PF00196 Bacterial regulatory proteins, luxR family 849 901 5.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 880 892 1.9E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 850 864 1.9E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 864 880 1.9E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 SUPERFAMILY SSF46894 842 902 5.78E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 Pfam PF14559 Tetratricopeptide repeat 683 746 8.8E-6 T 12-10-2018 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 Gene3D G3DSA:1.25.40.10 518 823 1.9E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 Gene3D G3DSA:1.10.10.10 824 905 8.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 Pfam PF13191 AAA ATPase domain 3 146 1.3E-18 T 12-10-2018 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 Gene3D G3DSA:3.40.50.300 1 177 7.6E-7 T 12-10-2018 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 SUPERFAMILY SSF48452 555 735 7.59E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25105 19233f4d5f82cf5d191fdc498aadb374 905 SUPERFAMILY SSF52540 4 209 2.84E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19445 8fd780c8e76781bf380c1316ad295771 284 SUPERFAMILY SSF51430 8 282 1.96E-65 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_19445 8fd780c8e76781bf380c1316ad295771 284 Pfam PF00248 Aldo/keto reductase family 16 282 1.5E-49 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_19445 8fd780c8e76781bf380c1316ad295771 284 Gene3D G3DSA:3.20.20.100 9 283 4.0E-66 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_19445 8fd780c8e76781bf380c1316ad295771 284 PRINTS PR00069 Aldo-keto reductase signature 146 163 1.5E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_19445 8fd780c8e76781bf380c1316ad295771 284 PRINTS PR00069 Aldo-keto reductase signature 216 240 1.5E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_19445 8fd780c8e76781bf380c1316ad295771 284 PRINTS PR00069 Aldo-keto reductase signature 111 129 1.5E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_19445 8fd780c8e76781bf380c1316ad295771 284 PRINTS PR00069 Aldo-keto reductase signature 46 70 1.5E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_19335 d78e53eb137f3803145e000716987b57 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 266 8.7E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_19335 d78e53eb137f3803145e000716987b57 275 Gene3D G3DSA:1.10.3720.10 3 262 1.7E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19335 d78e53eb137f3803145e000716987b57 275 SUPERFAMILY SSF161098 4 275 8.5E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 498 517 5.5E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 587 595 5.5E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 439 446 5.5E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 524 533 5.5E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Gene3D G3DSA:3.40.50.80 483 614 5.0E-32 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00410 Phenol hydroxylase reductase family signature 439 446 4.9E-8 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00410 Phenol hydroxylase reductase family signature 498 517 4.9E-8 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00410 Phenol hydroxylase reductase family signature 482 491 4.9E-8 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 PRINTS PR00410 Phenol hydroxylase reductase family signature 587 595 4.9E-8 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 SUPERFAMILY SSF63380 389 487 5.96E-24 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Gene3D G3DSA:2.40.30.10 383 482 3.1E-23 T 12-10-2018 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 SUPERFAMILY SSF54292 610 720 5.51E-23 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Gene3D G3DSA:2.30.110.10 171 300 7.4E-14 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 173 261 2.1E-5 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Pfam PF00175 Oxidoreductase NAD-binding domain 499 601 3.0E-16 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 SUPERFAMILY SSF50475 173 288 3.6E-11 T 12-10-2018 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 SUPERFAMILY SSF52343 478 617 5.11E-36 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Pfam PF00970 Oxidoreductase FAD-binding domain 396 488 1.7E-9 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 647 709 1.5E-10 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_29435 d3fbe297b164b0301eda24133ed83972 723 Gene3D G3DSA:3.10.20.30 615 722 1.4E-23 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_01720 37ae2e41515dd5fbdd4d430b17c6db17 510 Pfam PF00361 Proton-conducting membrane transporter 151 446 8.9E-73 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01720 37ae2e41515dd5fbdd4d430b17c6db17 510 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 9 499 17.377 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFR_01720 37ae2e41515dd5fbdd4d430b17c6db17 510 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 128 498 1.3E-109 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFR_23595 d71001c7d59f58ffd88f9c95582c2150 271 Gene3D G3DSA:3.20.20.370 75 271 4.4E-59 T 12-10-2018 AFR_23595 d71001c7d59f58ffd88f9c95582c2150 271 Pfam PF01522 Polysaccharide deacetylase 87 205 3.9E-29 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_23595 d71001c7d59f58ffd88f9c95582c2150 271 SUPERFAMILY SSF88713 81 270 1.56E-54 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_16235 36af53dfe0a0de5784213d2ca3171bac 83 Pfam PF11239 Protein of unknown function (DUF3040) 2 70 5.6E-8 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 AFR_36825 373c205f1c53fc6bfbdfb63425fe30bb 289 SUPERFAMILY SSF52540 2 238 4.18E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36825 373c205f1c53fc6bfbdfb63425fe30bb 289 SMART SM00382 27 210 2.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36825 373c205f1c53fc6bfbdfb63425fe30bb 289 Gene3D G3DSA:3.40.50.300 1 230 9.6E-57 T 12-10-2018 AFR_36825 373c205f1c53fc6bfbdfb63425fe30bb 289 Pfam PF00005 ABC transporter 19 162 1.7E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03470 a344a719fd6c01aa5d9130e2babbb538 206 SUPERFAMILY SSF55821 2 204 6.41E-61 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFR_03470 a344a719fd6c01aa5d9130e2babbb538 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 8.0E-56 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFR_03470 a344a719fd6c01aa5d9130e2babbb538 206 Pfam PF01300 Telomere recombination 23 198 6.1E-43 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFR_03470 a344a719fd6c01aa5d9130e2babbb538 206 Gene3D G3DSA:3.90.870.10 1 206 2.7E-61 T 12-10-2018 AFR_22520 4684eedccf25b2ef6594b9edf9135fa7 261 SUPERFAMILY SSF55729 61 254 4.8E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_22520 4684eedccf25b2ef6594b9edf9135fa7 261 Gene3D G3DSA:3.40.630.30 8 256 2.4E-31 T 12-10-2018 AFR_00205 b9bb128060507093321cc109be65214e 164 Gene3D G3DSA:1.10.10.10 5 147 1.5E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00205 b9bb128060507093321cc109be65214e 164 SMART SM00347 29 131 5.9E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_00205 b9bb128060507093321cc109be65214e 164 SUPERFAMILY SSF46785 11 146 7.21E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_00205 b9bb128060507093321cc109be65214e 164 Pfam PF12802 MarR family 36 95 1.6E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_30105 687efc7076aeab33618a1b71af3785d4 280 Gene3D G3DSA:1.10.3720.10 6 271 4.1E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30105 687efc7076aeab33618a1b71af3785d4 280 SUPERFAMILY SSF161098 15 280 2.62E-67 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30105 687efc7076aeab33618a1b71af3785d4 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 270 5.5E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_12625 4ef852bf8baafc97b3aa6159f3916f63 268 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 8 250 1.9E-59 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_12625 4ef852bf8baafc97b3aa6159f3916f63 268 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 253 6.0E-43 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_12625 4ef852bf8baafc97b3aa6159f3916f63 268 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 3 257 15.018 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_12625 4ef852bf8baafc97b3aa6159f3916f63 268 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 135 147 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 SUPERFAMILY SSF52374 119 418 4.56E-75 T 12-10-2018 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 SMART SM01016 4 93 6.3E-30 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 SMART SM00836 430 554 8.8E-49 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 Pfam PF00750 tRNA synthetases class I (R) 262 392 9.2E-10 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 33 554 5.1E-117 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 Gene3D G3DSA:3.30.1360.70 5 107 1.9E-20 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 Pfam PF05746 DALR anticodon binding domain 430 554 8.0E-34 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 SUPERFAMILY SSF55190 22 113 1.06E-19 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 5.3E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 5.3E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 5.3E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 5.3E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 SUPERFAMILY SSF47323 424 554 5.62E-34 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 Gene3D G3DSA:3.40.50.620 122 424 4.9E-143 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 29 93 2.4E-21 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 554 25.054 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFR_37495 afb287ba2cd45bbd5f17c7f0a7fd58e2 554 Gene3D G3DSA:1.10.730.10 425 554 4.9E-143 T 12-10-2018 AFR_26205 431e4a37088b947b63eebd452cb90e15 248 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_26205 431e4a37088b947b63eebd452cb90e15 248 SUPERFAMILY SSF52540 10 228 1.74E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26205 431e4a37088b947b63eebd452cb90e15 248 Pfam PF00005 ABC transporter 29 175 4.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_26205 431e4a37088b947b63eebd452cb90e15 248 SMART SM00382 38 224 8.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_26205 431e4a37088b947b63eebd452cb90e15 248 Gene3D G3DSA:3.40.50.300 8 245 4.4E-68 T 12-10-2018 AFR_28325 7effd05bcd02f521e3d0145e5ff9f541 303 Pfam PF00144 Beta-lactamase 45 296 3.7E-40 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_28325 7effd05bcd02f521e3d0145e5ff9f541 303 SUPERFAMILY SSF56601 43 282 3.18E-53 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_28325 7effd05bcd02f521e3d0145e5ff9f541 303 Gene3D G3DSA:3.40.710.10 39 302 5.8E-60 T 12-10-2018 AFR_13555 5707912684faa2d4e2250a911551fb51 250 Pfam PF00571 CBS domain 5 57 2.5E-11 T 12-10-2018 IPR000644 CBS domain AFR_13555 5707912684faa2d4e2250a911551fb51 250 Pfam PF00571 CBS domain 81 133 9.5E-11 T 12-10-2018 IPR000644 CBS domain AFR_13555 5707912684faa2d4e2250a911551fb51 250 PIRSF PIRSF036990 3 218 4.6E-45 T 12-10-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON AFR_13555 5707912684faa2d4e2250a911551fb51 250 SUPERFAMILY SSF54631 3 135 1.04E-30 T 12-10-2018 AFR_13555 5707912684faa2d4e2250a911551fb51 250 Gene3D G3DSA:3.10.580.10 1 152 3.2E-33 T 12-10-2018 AFR_13555 5707912684faa2d4e2250a911551fb51 250 SMART SM00116 12 60 1.5E-5 T 12-10-2018 IPR000644 CBS domain AFR_13555 5707912684faa2d4e2250a911551fb51 250 SMART SM00116 88 136 2.2E-4 T 12-10-2018 IPR000644 CBS domain AFR_13555 5707912684faa2d4e2250a911551fb51 250 Pfam PF04972 BON domain 138 204 1.3E-12 T 12-10-2018 IPR007055 BON domain AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 83 301 9.3E-45 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 17 315 23.834 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 Pfam PF02355 Protein export membrane protein 122 313 8.3E-53 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 PRINTS PR01755 Bacterial translocase SecF protein signature 164 178 3.0E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 PRINTS PR01755 Bacterial translocase SecF protein signature 212 230 3.0E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 PRINTS PR01755 Bacterial translocase SecF protein signature 247 262 3.0E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 PRINTS PR01755 Bacterial translocase SecF protein signature 44 59 3.0E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 Gene3D G3DSA:1.20.1640.10 114 324 7.2E-8 T 12-10-2018 AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 Pfam PF07549 SecD/SecF GG Motif 40 63 1.5E-5 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 SUPERFAMILY SSF82866 106 316 2.49E-31 T 12-10-2018 AFR_31045 a873e508f3206bbdf2c34511cee45a99 391 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 304 1.9E-58 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFR_01425 d0ec7fb9808726c47a3063e9602e65ca 91 SUPERFAMILY SSF46955 6 54 3.16E-10 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_01425 d0ec7fb9808726c47a3063e9602e65ca 91 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 55 2.5E-11 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_01425 d0ec7fb9808726c47a3063e9602e65ca 91 Pfam PF12728 Helix-turn-helix domain 7 57 9.7E-12 T 12-10-2018 AFR_01425 d0ec7fb9808726c47a3063e9602e65ca 91 Gene3D G3DSA:1.10.1660.10 7 64 9.2E-11 T 12-10-2018 AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Gene3D G3DSA:1.20.1610.10 809 983 2.1E-228 T 12-10-2018 AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Gene3D G3DSA:1.20.1050.60 714 808 2.1E-228 T 12-10-2018 AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Gene3D G3DSA:2.60.120.260 1140 1263 1.1E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Gene3D G3DSA:2.60.40.10 1562 1650 1.8E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 377 1112 6.6E-129 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Gene3D G3DSA:3.30.2080.10 644 1112 2.1E-228 T 12-10-2018 AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Gene3D G3DSA:2.70.98.10 383 713 2.1E-228 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 SUPERFAMILY SSF48208 608 1092 1.36E-17 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Pfam PF07971 Glycosyl hydrolase family 92 586 1109 6.0E-142 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 SUPERFAMILY SSF49785 73 184 4.0E-11 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 Gene3D G3DSA:2.60.120.260 65 199 3.1E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_14325 a2c7b3f766eb83b123a5b6fd7ac7e223 1650 SUPERFAMILY SSF49299 1563 1649 2.09E-7 T 12-10-2018 IPR035986 PKD domain superfamily AFR_31640 c236aa8c24c4029207b08db68270216c 199 Gene3D G3DSA:2.60.40.10 81 189 3.6E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31640 c236aa8c24c4029207b08db68270216c 199 SUPERFAMILY SSF49265 89 176 8.96E-7 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_31640 c236aa8c24c4029207b08db68270216c 199 Pfam PF00041 Fibronectin type III domain 98 177 8.1E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_33535 0a70c9d8040b0b983c506659edfde0d2 304 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_33535 0a70c9d8040b0b983c506659edfde0d2 304 SMART SM00382 30 208 3.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33535 0a70c9d8040b0b983c506659edfde0d2 304 SUPERFAMILY SSF52540 4 223 1.78E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33535 0a70c9d8040b0b983c506659edfde0d2 304 Gene3D G3DSA:3.40.50.300 1 228 7.9E-59 T 12-10-2018 AFR_33535 0a70c9d8040b0b983c506659edfde0d2 304 Pfam PF00005 ABC transporter 22 160 1.2E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18175 29497724128e8631830dbd8c1b41098e 881 Gene3D G3DSA:2.60.120.380 781 881 5.2E-7 T 12-10-2018 AFR_39565 303c2353566170df322a17f0c22bea8a 425 Gene3D G3DSA:3.90.1170.30 322 411 4.5E-132 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 336 410 1.6E-19 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 Gene3D G3DSA:3.40.1030.10 80 321 4.5E-132 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 Pfam PF00591 Glycosyl transferase family, a/b domain 80 304 1.7E-33 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 SUPERFAMILY SSF52418 72 318 1.31E-81 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 69 9.8E-20 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 SUPERFAMILY SSF54680 323 424 2.35E-23 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 113 128 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 PIRSF PIRSF000478 3 425 1.1E-152 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 SMART SM00941 336 410 2.4E-27 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 7 405 1.4E-167 T 12-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 SUPERFAMILY SSF47648 5 72 2.62E-21 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_39565 303c2353566170df322a17f0c22bea8a 425 Gene3D G3DSA:1.20.970.10 5 70 2.5E-23 T 12-10-2018 AFR_11285 c7f6954e6f957155f9d85283d2c4f3f5 128 Gene3D G3DSA:3.10.450.50 1 127 3.9E-30 T 12-10-2018 AFR_11285 c7f6954e6f957155f9d85283d2c4f3f5 128 SUPERFAMILY SSF54427 2 127 1.07E-26 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_11285 c7f6954e6f957155f9d85283d2c4f3f5 128 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 5 124 1.0E-22 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 AFR_11285 c7f6954e6f957155f9d85283d2c4f3f5 128 Pfam PF14534 Domain of unknown function (DUF4440) 6 116 9.1E-14 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 AFR_21905 348f74b9547f5fa148ec749f4a579246 566 SUPERFAMILY SSF51445 283 535 8.33E-23 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_21905 348f74b9547f5fa148ec749f4a579246 566 Gene3D G3DSA:3.20.20.80 264 557 4.3E-50 T 12-10-2018 AFR_06715 f4a91a912f411e48c706cd5515408136 407 SUPERFAMILY SSF55781 146 202 2.94E-7 T 12-10-2018 AFR_06715 f4a91a912f411e48c706cd5515408136 407 SUPERFAMILY SSF55874 296 403 8.91E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_06715 f4a91a912f411e48c706cd5515408136 407 Gene3D G3DSA:3.30.565.10 284 403 4.9E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_06715 f4a91a912f411e48c706cd5515408136 407 SMART SM00387 314 405 7.6E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_06715 f4a91a912f411e48c706cd5515408136 407 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 402 4.1E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_06715 f4a91a912f411e48c706cd5515408136 407 Gene3D G3DSA:3.30.450.40 84 203 9.3E-7 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_06715 f4a91a912f411e48c706cd5515408136 407 Pfam PF07730 Histidine kinase 213 279 1.8E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_31335 43c776fb9b8a9c3e183178acfa1ac6b7 529 Gene3D G3DSA:3.50.50.60 2 124 9.7E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_31335 43c776fb9b8a9c3e183178acfa1ac6b7 529 Gene3D G3DSA:3.50.50.60 213 309 9.5E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_31335 43c776fb9b8a9c3e183178acfa1ac6b7 529 SUPERFAMILY SSF51905 4 502 1.11E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_31335 43c776fb9b8a9c3e183178acfa1ac6b7 529 Pfam PF01593 Flavin containing amine oxidoreductase 15 283 1.3E-12 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_31335 43c776fb9b8a9c3e183178acfa1ac6b7 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.6E-5 T 12-10-2018 AFR_31335 43c776fb9b8a9c3e183178acfa1ac6b7 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 182 3.6E-5 T 12-10-2018 AFR_31335 43c776fb9b8a9c3e183178acfa1ac6b7 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 3.6E-5 T 12-10-2018 AFR_10315 075fc52c28aaf9d0a8a41e01fb65dc6c 267 Gene3D G3DSA:3.20.20.70 2 266 8.6E-86 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10315 075fc52c28aaf9d0a8a41e01fb65dc6c 267 SUPERFAMILY SSF51366 3 241 3.3E-73 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_10315 075fc52c28aaf9d0a8a41e01fb65dc6c 267 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 13 261 30.796 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_10315 075fc52c28aaf9d0a8a41e01fb65dc6c 267 Pfam PF00290 Tryptophan synthase alpha chain 7 255 2.2E-69 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_10315 075fc52c28aaf9d0a8a41e01fb65dc6c 267 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 10 257 4.6E-61 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 SUPERFAMILY SSF90123 20 335 7.46E-71 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 Gene3D G3DSA:1.20.1560.10 6 335 6.9E-79 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 SUPERFAMILY SSF52540 340 579 8.88E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 Gene3D G3DSA:3.40.50.300 338 585 4.7E-87 T 12-10-2018 AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 Pfam PF00005 ABC transporter 363 512 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 SMART SM00382 372 558 2.4E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_31730 c8b0110368981e7ad470aa159bfe385f 586 Pfam PF00664 ABC transporter transmembrane region 33 299 4.3E-36 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_38725 4d29e77af89c28321072b83e811136fb 334 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 11 331 2.4E-84 T 12-10-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin AFR_38725 4d29e77af89c28321072b83e811136fb 334 SUPERFAMILY SSF52743 5 274 6.55E-78 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_38725 4d29e77af89c28321072b83e811136fb 334 Gene3D G3DSA:3.40.50.200 1 276 4.2E-80 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_38725 4d29e77af89c28321072b83e811136fb 334 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 27 38 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_38725 4d29e77af89c28321072b83e811136fb 334 PRINTS PR00723 Subtilisin serine protease family (S8) signature 213 229 1.1E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_38725 4d29e77af89c28321072b83e811136fb 334 PRINTS PR00723 Subtilisin serine protease family (S8) signature 22 41 1.1E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_38725 4d29e77af89c28321072b83e811136fb 334 PRINTS PR00723 Subtilisin serine protease family (S8) signature 61 74 1.1E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_38725 4d29e77af89c28321072b83e811136fb 334 Pfam PF00082 Subtilase family 22 264 1.2E-42 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_12255 37d092eeed54c495ca1b1e2d56e413fa 108 Gene3D G3DSA:3.40.630.30 6 99 2.9E-25 T 12-10-2018 AFR_12255 37d092eeed54c495ca1b1e2d56e413fa 108 Pfam PF14542 GCN5-related N-acetyl-transferase 15 92 1.3E-24 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase AFR_12255 37d092eeed54c495ca1b1e2d56e413fa 108 SUPERFAMILY SSF55729 5 93 2.49E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 Gene3D G3DSA:3.20.20.80 4 456 5.5E-181 T 12-10-2018 AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 Gene3D G3DSA:3.90.400.10 103 172 5.5E-181 T 12-10-2018 AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 SUPERFAMILY SSF51445 4 457 5.37E-109 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 Pfam PF00128 Alpha amylase, catalytic domain 28 385 8.2E-71 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 SMART SM00642 13 396 8.1E-89 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 PRINTS PR00110 Alpha-amylase signature 302 314 7.1E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 PRINTS PR00110 Alpha-amylase signature 194 205 7.1E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_37790 d4e62e30639b5de86db1895dedd7adbf 548 PRINTS PR00110 Alpha-amylase signature 92 103 7.1E-5 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AFR_09405 f436556d50ea44314d700890b8866f27 354 Gene3D G3DSA:3.40.1030.10 80 352 9.5E-94 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_09405 f436556d50ea44314d700890b8866f27 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 11 343 2.7E-104 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFR_09405 f436556d50ea44314d700890b8866f27 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 9 68 1.5E-17 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_09405 f436556d50ea44314d700890b8866f27 354 SUPERFAMILY SSF52418 82 345 5.89E-79 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_09405 f436556d50ea44314d700890b8866f27 354 Pfam PF00591 Glycosyl transferase family, a/b domain 81 334 2.0E-79 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_09405 f436556d50ea44314d700890b8866f27 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 8 344 33.228 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFR_09405 f436556d50ea44314d700890b8866f27 354 Gene3D G3DSA:1.20.970.10 4 69 8.7E-27 T 12-10-2018 AFR_09405 f436556d50ea44314d700890b8866f27 354 SUPERFAMILY SSF47648 6 73 2.75E-17 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_26680 68ee2febc3df644978c30e4db50b1ede 436 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 78 87 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFR_26680 68ee2febc3df644978c30e4db50b1ede 436 Pfam PF01546 Peptidase family M20/M25/M40 79 434 1.2E-36 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_26680 68ee2febc3df644978c30e4db50b1ede 436 Gene3D G3DSA:3.40.630.10 4 202 5.2E-48 T 12-10-2018 AFR_26680 68ee2febc3df644978c30e4db50b1ede 436 SUPERFAMILY SSF53187 7 434 1.49E-54 T 12-10-2018 AFR_26680 68ee2febc3df644978c30e4db50b1ede 436 SUPERFAMILY SSF55031 199 320 3.98E-11 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFR_26680 68ee2febc3df644978c30e4db50b1ede 436 Pfam PF07687 Peptidase dimerisation domain 196 320 1.8E-14 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 1.7E-162 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 Pfam PF00709 Adenylosuccinate synthetase 4 421 1.4E-174 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 Gene3D G3DSA:3.40.440.10 5 258 1.0E-94 T 12-10-2018 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 Gene3D G3DSA:1.10.300.10 100 199 1.0E-94 T 12-10-2018 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 193.391 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 SMART SM00788 3 422 2.4E-273 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 SUPERFAMILY SSF52540 2 426 9.24E-168 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00680 01269d2e18072de9fc63c2934d62faf4 430 Gene3D G3DSA:3.90.170.10 265 428 2.5E-67 T 12-10-2018 AFR_36195 4c1f0835e18ec3865fae6464818f3efa 392 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 30 376 2.2E-93 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 AFR_36195 4c1f0835e18ec3865fae6464818f3efa 392 Gene3D G3DSA:3.20.20.70 92 362 5.9E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_36195 4c1f0835e18ec3865fae6464818f3efa 392 PIRSF PIRSF006004 21 387 4.3E-118 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 AFR_36195 4c1f0835e18ec3865fae6464818f3efa 392 Pfam PF04055 Radical SAM superfamily 132 305 2.3E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_36195 4c1f0835e18ec3865fae6464818f3efa 392 Gene3D G3DSA:1.10.150.530 28 85 1.0E-7 T 12-10-2018 AFR_36195 4c1f0835e18ec3865fae6464818f3efa 392 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 27 377 67.477 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 AFR_36195 4c1f0835e18ec3865fae6464818f3efa 392 SUPERFAMILY SSF102114 123 347 4.58E-15 T 12-10-2018 AFR_12900 1dda9af4d30d567db884d84254f60f4c 277 SMART SM00530 9 81 3.3E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_12900 1dda9af4d30d567db884d84254f60f4c 277 Pfam PF13560 Helix-turn-helix domain 5 84 3.8E-15 T 12-10-2018 AFR_12900 1dda9af4d30d567db884d84254f60f4c 277 SUPERFAMILY SSF47413 29 77 2.09E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_12900 1dda9af4d30d567db884d84254f60f4c 277 Gene3D G3DSA:3.30.450.180 103 274 3.2E-10 T 12-10-2018 AFR_12900 1dda9af4d30d567db884d84254f60f4c 277 Gene3D G3DSA:1.10.260.40 3 80 1.3E-6 T 12-10-2018 AFR_31050 da913cefb290259edbfd54a8ceebcb74 624 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 39 592 9.8E-96 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFR_31050 da913cefb290259edbfd54a8ceebcb74 624 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 374 585 6.2E-54 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFR_31050 da913cefb290259edbfd54a8ceebcb74 624 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 608 36.322 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFR_31050 da913cefb290259edbfd54a8ceebcb74 624 SUPERFAMILY SSF82866 399 598 1.44E-35 T 12-10-2018 AFR_31050 da913cefb290259edbfd54a8ceebcb74 624 Gene3D G3DSA:3.30.70.3400 39 126 7.1E-18 T 12-10-2018 AFR_31050 da913cefb290259edbfd54a8ceebcb74 624 Pfam PF02355 Protein export membrane protein 424 597 4.2E-9 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFR_31050 da913cefb290259edbfd54a8ceebcb74 624 Gene3D G3DSA:3.30.1360.200 271 418 1.7E-22 T 12-10-2018 AFR_34640 41579653f7ca15d3468609661c446dd5 267 Gene3D G3DSA:3.40.50.150 2 267 9.8E-99 T 12-10-2018 AFR_34640 41579653f7ca15d3468609661c446dd5 267 PIRSF PIRSF017393 1 267 6.3E-89 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_34640 41579653f7ca15d3468609661c446dd5 267 SUPERFAMILY SSF53335 17 245 2.13E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_34640 41579653f7ca15d3468609661c446dd5 267 Pfam PF04672 S-adenosyl methyltransferase 8 267 2.1E-81 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 SUPERFAMILY SSF54427 175 263 1.34E-10 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 Pfam PF08281 Sigma-70, region 4 107 157 3.8E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 Gene3D G3DSA:1.10.1740.10 2 86 7.8E-20 T 12-10-2018 AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 Gene3D G3DSA:1.10.10.10 90 162 2.7E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 159 1.8E-16 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 Pfam PF04542 Sigma-70 region 2 7 73 5.8E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 SUPERFAMILY SSF88946 5 89 4.71E-20 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 SUPERFAMILY SSF88659 101 159 1.25E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 Gene3D G3DSA:3.10.450.50 169 280 3.9E-9 T 12-10-2018 AFR_22845 2285d7b11e6c106544f1bfb19002bf7f 287 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 28 59 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_08695 6b28c626a46e3e93a35a8543d6987602 316 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 314 2.2E-97 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_08695 6b28c626a46e3e93a35a8543d6987602 316 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 225 314 5.7E-28 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_08695 6b28c626a46e3e93a35a8543d6987602 316 Gene3D G3DSA:3.40.47.10 2 316 6.1E-104 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_08695 6b28c626a46e3e93a35a8543d6987602 316 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 315 59.657 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_08695 6b28c626a46e3e93a35a8543d6987602 316 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 9.2E-28 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_08695 6b28c626a46e3e93a35a8543d6987602 316 SUPERFAMILY SSF53901 5 315 3.59E-64 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_22650 7421ca1fd5c40f36df5018d03fd691ab 282 PIRSF PIRSF005295 2 259 2.8E-102 T 12-10-2018 IPR012022 Protein of unknown function UCP005295 AFR_22650 7421ca1fd5c40f36df5018d03fd691ab 282 SUPERFAMILY SSF51556 2 256 4.77E-46 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_22650 7421ca1fd5c40f36df5018d03fd691ab 282 Pfam PF01026 TatD related DNase 4 225 1.2E-10 T 12-10-2018 IPR001130 TatD family GO:0016788 AFR_22650 7421ca1fd5c40f36df5018d03fd691ab 282 Gene3D G3DSA:3.20.20.140 2 262 4.1E-45 T 12-10-2018 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 PIRSF PIRSF002133 1 124 1.2E-53 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.5E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.5E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.5E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.5E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.5E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.5E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 Gene3D G3DSA:2.40.50.140 1 124 1.2E-61 T 12-10-2018 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 1.9E-42 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 SUPERFAMILY SSF50249 2 123 4.8E-52 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.821 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04480 2db5858f44b9b0e6f8ce1ac1845325fd 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 1.1E-66 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42415 80341e50f6154779f7f772ec353dc0f8 425 Pfam PF13692 Glycosyl transferases group 1 245 378 2.1E-18 T 12-10-2018 AFR_42415 80341e50f6154779f7f772ec353dc0f8 425 Pfam PF13579 Glycosyl transferase 4-like domain 57 231 2.6E-20 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_42415 80341e50f6154779f7f772ec353dc0f8 425 SUPERFAMILY SSF53756 44 416 2.09E-48 T 12-10-2018 AFR_42415 80341e50f6154779f7f772ec353dc0f8 425 Gene3D G3DSA:3.40.50.2000 239 389 4.2E-26 T 12-10-2018 AFR_36280 0b9e7eca305fd289fdaf6bdcdddf7279 124 SUPERFAMILY SSF51261 10 114 7.85E-17 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_36280 0b9e7eca305fd289fdaf6bdcdddf7279 124 Pfam PF01551 Peptidase family M23 15 110 6.1E-16 T 12-10-2018 IPR016047 Peptidase M23 AFR_36280 0b9e7eca305fd289fdaf6bdcdddf7279 124 Gene3D G3DSA:2.70.70.10 1 115 1.1E-18 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_14780 9e2be2ce4d74f2a59068f2da7ed61ded 293 SUPERFAMILY SSF161098 43 269 1.31E-59 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14780 9e2be2ce4d74f2a59068f2da7ed61ded 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 277 5.5E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_14780 9e2be2ce4d74f2a59068f2da7ed61ded 293 Gene3D G3DSA:1.10.3720.10 39 281 8.2E-70 T 12-10-2018 IPR035906 MetI-like superfamily AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 SUPERFAMILY SSF52540 309 518 6.2E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 Gene3D G3DSA:3.40.50.300 293 525 4.5E-51 T 12-10-2018 AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 SUPERFAMILY SSF52540 3 232 2.76E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 Pfam PF00005 ABC transporter 345 473 3.0E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 Pfam PF00005 ABC transporter 20 189 3.8E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 SMART SM00382 26 234 5.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 SMART SM00382 352 519 2.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10780 6ab287d3f42fcf689fe3bbbd434df0a6 534 Pfam PF12848 ABC transporter 232 306 1.8E-8 T 12-10-2018 IPR032781 ABC-transporter extension domain AFR_24770 17881e19f1f55e8d78b001bbb5209a28 298 Gene3D G3DSA:3.40.50.1820 32 298 1.7E-80 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_24770 17881e19f1f55e8d78b001bbb5209a28 298 Pfam PF12695 Alpha/beta hydrolase family 151 223 2.0E-7 T 12-10-2018 IPR029059 Alpha/beta hydrolase fold-5 AFR_24770 17881e19f1f55e8d78b001bbb5209a28 298 SUPERFAMILY SSF53474 43 281 1.86E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32325 5c0b15284a41931ab7b662ebcecdd322 407 Pfam PF05977 Transmembrane secretion effector 4 382 4.0E-20 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_32325 5c0b15284a41931ab7b662ebcecdd322 407 SUPERFAMILY SSF103473 4 384 2.75E-34 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_32325 5c0b15284a41931ab7b662ebcecdd322 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 135 156 5.4E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32325 5c0b15284a41931ab7b662ebcecdd322 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 246 263 5.4E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32325 5c0b15284a41931ab7b662ebcecdd322 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 6 28 5.4E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32325 5c0b15284a41931ab7b662ebcecdd322 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 69 87 5.4E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32325 5c0b15284a41931ab7b662ebcecdd322 407 Gene3D G3DSA:1.20.1250.20 2 380 2.9E-30 T 12-10-2018 AFR_36315 dd50b5351289e0666865fe4157f224d7 254 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 254 97.956 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFR_36315 dd50b5351289e0666865fe4157f224d7 254 PIRSF PIRSF000386 1 247 5.0E-89 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFR_36315 dd50b5351289e0666865fe4157f224d7 254 SUPERFAMILY SSF75217 2 235 6.34E-87 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFR_36315 dd50b5351289e0666865fe4157f224d7 254 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 1.1E-71 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFR_36315 dd50b5351289e0666865fe4157f224d7 254 Gene3D G3DSA:1.10.1270.20 164 248 8.6E-28 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFR_36315 dd50b5351289e0666865fe4157f224d7 254 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 221 2.4E-62 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFR_36315 dd50b5351289e0666865fe4157f224d7 254 Gene3D G3DSA:3.40.1280.10 1 163 3.2E-64 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFR_27450 b2695fe498af56277c60569bda8c38f9 235 SMART SM00346 1 79 1.6E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_27450 b2695fe498af56277c60569bda8c38f9 235 Gene3D G3DSA:1.10.10.10 1 59 9.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27450 b2695fe498af56277c60569bda8c38f9 235 Pfam PF01614 Bacterial transcriptional regulator 109 228 9.4E-28 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_27450 b2695fe498af56277c60569bda8c38f9 235 SUPERFAMILY SSF46785 2 61 1.79E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27450 b2695fe498af56277c60569bda8c38f9 235 Gene3D G3DSA:3.30.450.40 60 235 2.1E-35 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_27450 b2695fe498af56277c60569bda8c38f9 235 SUPERFAMILY SSF55781 55 231 1.44E-34 T 12-10-2018 AFR_27450 b2695fe498af56277c60569bda8c38f9 235 Pfam PF09339 IclR helix-turn-helix domain 2 41 4.1E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_34630 8b5f9ca0d5afb0b153d215400e7dae61 344 PIRSF PIRSF015921 2 344 8.6E-74 T 12-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 AFR_34630 8b5f9ca0d5afb0b153d215400e7dae61 344 Pfam PF00487 Fatty acid desaturase 60 315 3.9E-40 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 AFR_40105 7c2bef6801d776125893f79a08885d9b 208 Pfam PF03352 Methyladenine glycosylase 25 195 1.1E-62 T 12-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 AFR_40105 7c2bef6801d776125893f79a08885d9b 208 Gene3D G3DSA:1.10.340.30 20 201 3.1E-68 T 12-10-2018 AFR_40105 7c2bef6801d776125893f79a08885d9b 208 SUPERFAMILY SSF48150 21 197 2.72E-64 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_03080 05e125f89706a942aee187962b7eeb63 952 Pfam PF00754 F5/8 type C domain 579 701 2.0E-14 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_03080 05e125f89706a942aee187962b7eeb63 952 Gene3D G3DSA:2.70.98.10 28 332 5.9E-83 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_03080 05e125f89706a942aee187962b7eeb63 952 Gene3D G3DSA:3.30.2080.10 811 938 4.0E-78 T 12-10-2018 AFR_03080 05e125f89706a942aee187962b7eeb63 952 Gene3D G3DSA:3.30.2080.10 333 578 1.3E-52 T 12-10-2018 AFR_03080 05e125f89706a942aee187962b7eeb63 952 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 31 563 2.0E-92 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_03080 05e125f89706a942aee187962b7eeb63 952 Gene3D G3DSA:2.60.120.260 579 706 1.3E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_03080 05e125f89706a942aee187962b7eeb63 952 Gene3D G3DSA:1.20.1610.10 719 810 4.0E-78 T 12-10-2018 AFR_03080 05e125f89706a942aee187962b7eeb63 952 Pfam PF07971 Glycosyl hydrolase family 92 279 934 3.0E-178 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_03080 05e125f89706a942aee187962b7eeb63 952 SUPERFAMILY SSF48208 306 560 1.02E-11 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_03080 05e125f89706a942aee187962b7eeb63 952 SUPERFAMILY SSF49785 578 703 1.28E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 PIRSF PIRSF000077 1 104 5.9E-26 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 Pfam PF00085 Thioredoxin 4 102 1.0E-25 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 PRINTS PR00421 Thioredoxin family signature 21 29 6.5E-6 T 12-10-2018 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 PRINTS PR00421 Thioredoxin family signature 68 79 6.5E-6 T 12-10-2018 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 PRINTS PR00421 Thioredoxin family signature 29 38 6.5E-6 T 12-10-2018 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 Gene3D G3DSA:3.40.30.10 1 116 2.6E-30 T 12-10-2018 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 2.1E-29 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFR_39990 4d21896fa8ba4b397b62ac10428578da 120 SUPERFAMILY SSF52833 4 102 3.03E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_08180 cb3c56dc751ee3a746f19069052a053e 306 Gene3D G3DSA:3.40.50.300 2 240 7.4E-70 T 12-10-2018 AFR_08180 cb3c56dc751ee3a746f19069052a053e 306 SUPERFAMILY SSF52540 4 227 3.59E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08180 cb3c56dc751ee3a746f19069052a053e 306 Pfam PF00005 ABC transporter 20 162 7.2E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_08180 cb3c56dc751ee3a746f19069052a053e 306 SMART SM00382 28 219 2.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08180 cb3c56dc751ee3a746f19069052a053e 306 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 SUPERFAMILY SSF53244 314 444 1.03E-31 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 Pfam PF01225 Mur ligase family, catalytic domain 26 90 7.8E-9 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 SUPERFAMILY SSF53623 99 307 1.96E-50 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 Gene3D G3DSA:3.40.1190.10 79 308 1.7E-67 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 Gene3D G3DSA:3.40.1390.10 1 78 4.9E-19 T 12-10-2018 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 30 442 1.5E-117 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 SUPERFAMILY SSF63418 1 93 2.09E-20 T 12-10-2018 IPR035911 MurE/MurF, N-terminal AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 394 2.8E-19 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 Pfam PF08245 Mur ligase middle domain 105 291 5.6E-42 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 453 31.221 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_09995 8c477da22e3a65f002af3fdf45ea98b9 462 Gene3D G3DSA:3.90.190.20 311 459 7.7E-35 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.8E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 SMART SM00345 15 74 4.5E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 Gene3D G3DSA:1.10.10.10 9 74 3.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 SUPERFAMILY SSF48008 93 217 1.41E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 Pfam PF07729 FCD domain 95 216 7.4E-20 T 12-10-2018 IPR011711 GntR, C-terminal AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 Gene3D G3DSA:1.20.120.530 92 221 6.3E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 SUPERFAMILY SSF46785 8 78 7.21E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13455 899b6da619f78fb1b5238328fcca35cb 227 SMART SM00895 95 217 1.4E-16 T 12-10-2018 IPR011711 GntR, C-terminal AFR_11080 0487d1aaf85be13c99f1ccb6fd9c2883 271 SUPERFAMILY SSF47413 28 78 1.27E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_11080 0487d1aaf85be13c99f1ccb6fd9c2883 271 Gene3D G3DSA:3.30.450.180 101 270 1.6E-13 T 12-10-2018 AFR_11080 0487d1aaf85be13c99f1ccb6fd9c2883 271 Pfam PF13560 Helix-turn-helix domain 4 81 1.3E-15 T 12-10-2018 AFR_11080 0487d1aaf85be13c99f1ccb6fd9c2883 271 Gene3D G3DSA:1.10.260.40 1 87 9.0E-8 T 12-10-2018 AFR_11080 0487d1aaf85be13c99f1ccb6fd9c2883 271 SMART SM00530 8 81 1.7E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_18925 38083f1275ec79924fed20042999a6a7 974 Gene3D G3DSA:2.170.160.10 429 657 1.9E-298 T 12-10-2018 IPR023309 Endoglucanase F, domain 2 AFR_18925 38083f1275ec79924fed20042999a6a7 974 SMART SM00637 40 140 1.7E-37 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18925 38083f1275ec79924fed20042999a6a7 974 Pfam PF02011 Glycosyl hydrolase family 48 347 971 0.0 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 Gene3D G3DSA:2.60.40.290 34 142 6.4E-32 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_18925 38083f1275ec79924fed20042999a6a7 974 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 105 118 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 AFR_18925 38083f1275ec79924fed20042999a6a7 974 Gene3D G3DSA:4.10.870.10 883 954 1.9E-298 T 12-10-2018 IPR027390 Endoglucanase F, domain 3 AFR_18925 38083f1275ec79924fed20042999a6a7 974 SUPERFAMILY SSF48208 342 973 3.29E-280 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_18925 38083f1275ec79924fed20042999a6a7 974 SUPERFAMILY SSF49384 36 141 3.07E-27 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_18925 38083f1275ec79924fed20042999a6a7 974 Gene3D G3DSA:2.60.40.10 148 243 3.0E-21 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 625 644 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 394 411 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 695 718 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 554 581 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 795 815 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 741 767 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 509 533 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 904 932 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 368 393 6.3E-103 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 AFR_18925 38083f1275ec79924fed20042999a6a7 974 Pfam PF00553 Cellulose binding domain 40 140 2.2E-27 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18925 38083f1275ec79924fed20042999a6a7 974 Gene3D G3DSA:1.50.10.10 347 971 1.9E-298 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 Pfam PF03413 Peptidase propeptide and YPEB domain 121 189 1.4E-5 T 12-10-2018 IPR025711 PepSY domain AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 Gene3D G3DSA:3.10.170.10 196 348 3.7E-47 T 12-10-2018 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 70 107 2.9E-7 T 12-10-2018 IPR011096 FTP domain AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 421 437 8.5E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 335 351 8.5E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 298 318 8.5E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 356 367 8.5E-20 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 Gene3D G3DSA:1.10.390.10 349 519 8.0E-52 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 347 519 1.8E-51 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 197 344 6.4E-45 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 AFR_19635 e9412b9be9b36ba7e7f1a3c6bcc3ae38 520 SUPERFAMILY SSF55486 194 519 2.56E-80 T 12-10-2018 AFR_22490 4bb9db62aeecb9fa6551a227808c39a8 283 SUPERFAMILY SSF51569 4 276 2.05E-75 T 12-10-2018 AFR_22490 4bb9db62aeecb9fa6551a227808c39a8 283 PIRSF PIRSF001359 1 281 1.6E-66 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_22490 4bb9db62aeecb9fa6551a227808c39a8 283 Gene3D G3DSA:3.20.20.70 1 280 4.5E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_22490 4bb9db62aeecb9fa6551a227808c39a8 283 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 275 7.7E-77 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_22490 4bb9db62aeecb9fa6551a227808c39a8 283 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 2 276 1.3E-66 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_36870 6c570384919e00f9deed914cc3949b73 533 SUPERFAMILY SSF55021 455 519 8.81E-15 T 12-10-2018 AFR_36870 6c570384919e00f9deed914cc3949b73 533 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 143 170 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFR_36870 6c570384919e00f9deed914cc3949b73 533 Gene3D G3DSA:3.40.50.720 97 278 2.5E-118 T 12-10-2018 AFR_36870 6c570384919e00f9deed914cc3949b73 533 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 5 519 1.3E-180 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 AFR_36870 6c570384919e00f9deed914cc3949b73 533 Gene3D G3DSA:3.30.70.260 456 530 1.6E-24 T 12-10-2018 AFR_36870 6c570384919e00f9deed914cc3949b73 533 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 280 1.8E-60 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFR_36870 6c570384919e00f9deed914cc3949b73 533 Gene3D G3DSA:3.40.50.720 6 304 2.5E-118 T 12-10-2018 AFR_36870 6c570384919e00f9deed914cc3949b73 533 SUPERFAMILY SSF52283 1 134 7.37E-37 T 12-10-2018 AFR_36870 6c570384919e00f9deed914cc3949b73 533 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 312 6.3E-32 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFR_36870 6c570384919e00f9deed914cc3949b73 533 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFR_36870 6c570384919e00f9deed914cc3949b73 533 SUPERFAMILY SSF51735 100 280 2.47E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36870 6c570384919e00f9deed914cc3949b73 533 SUPERFAMILY SSF143548 321 451 5.23E-29 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFR_36870 6c570384919e00f9deed914cc3949b73 533 Pfam PF01842 ACT domain 457 518 2.4E-10 T 12-10-2018 IPR002912 ACT domain AFR_36870 6c570384919e00f9deed914cc3949b73 533 Gene3D G3DSA:3.30.1330.90 315 455 1.1E-37 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFR_36870 6c570384919e00f9deed914cc3949b73 533 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 SUPERFAMILY SSF46785 7 151 1.88E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 Pfam PF12802 MarR family 38 100 3.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 1.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 1.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 1.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 127 147 1.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 SMART SM00347 33 137 9.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20900 e09213eddfbe3e0ee7e33e892faff10d 164 Gene3D G3DSA:1.10.10.10 2 152 1.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_18325 8723f08beb8b576e1cc435c29a5ac970 242 SUPERFAMILY SSF52540 3 239 2.21E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18325 8723f08beb8b576e1cc435c29a5ac970 242 SMART SM00382 27 219 6.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18325 8723f08beb8b576e1cc435c29a5ac970 242 Gene3D G3DSA:3.40.50.300 2 238 5.1E-55 T 12-10-2018 AFR_18325 8723f08beb8b576e1cc435c29a5ac970 242 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 219 241 1.0E-5 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFR_18325 8723f08beb8b576e1cc435c29a5ac970 242 Pfam PF00005 ABC transporter 18 170 1.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_27540 cd5517f09d4012709c868ccaf910c5e8 433 Pfam PF00202 Aminotransferase class-III 27 425 2.1E-87 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27540 cd5517f09d4012709c868ccaf910c5e8 433 SUPERFAMILY SSF53383 8 425 4.08E-106 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_27540 cd5517f09d4012709c868ccaf910c5e8 433 Gene3D G3DSA:3.40.640.10 60 324 2.3E-123 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_27540 cd5517f09d4012709c868ccaf910c5e8 433 Gene3D G3DSA:3.90.1150.10 4 421 2.3E-123 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_27540 cd5517f09d4012709c868ccaf910c5e8 433 PIRSF PIRSF000521 121 428 2.6E-41 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27540 cd5517f09d4012709c868ccaf910c5e8 433 PIRSF PIRSF000521 15 130 1.3E-5 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27070 5e77e7de4bac4b89283ce183a0ea5fc2 153 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 3.9E-40 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_27070 5e77e7de4bac4b89283ce183a0ea5fc2 153 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 98 7.9E-16 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_27070 5e77e7de4bac4b89283ce183a0ea5fc2 153 Gene3D G3DSA:2.30.110.10 10 143 1.9E-38 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_27070 5e77e7de4bac4b89283ce183a0ea5fc2 153 SUPERFAMILY SSF50475 13 149 4.61E-33 T 12-10-2018 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 Gene3D G3DSA:3.30.300.20 17 106 1.7E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 1.4E-34 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 Pfam PF07650 KH domain 37 109 3.1E-19 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 Gene3D G3DSA:3.30.1140.32 107 208 2.0E-37 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 SMART SM00322 59 124 2.8E-7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 SUPERFAMILY SSF54821 106 206 5.23E-35 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 4.0E-91 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 SUPERFAMILY SSF54814 2 105 3.66E-35 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFR_04535 13a19122d14adfdb99827e5c33868f9f 291 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.542 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFR_38015 02920cbf8abb6f7dcbb3a9d8e55c9020 299 SUPERFAMILY SSF50129 2 130 1.36E-27 T 12-10-2018 IPR011032 GroES-like superfamily AFR_38015 02920cbf8abb6f7dcbb3a9d8e55c9020 299 SUPERFAMILY SSF51735 109 272 7.9E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38015 02920cbf8abb6f7dcbb3a9d8e55c9020 299 Gene3D G3DSA:3.90.180.10 1 297 3.5E-65 T 12-10-2018 AFR_38015 02920cbf8abb6f7dcbb3a9d8e55c9020 299 Pfam PF00107 Zinc-binding dehydrogenase 144 260 6.1E-17 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_38015 02920cbf8abb6f7dcbb3a9d8e55c9020 299 SMART SM00829 1 295 2.1E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_17530 ac6ee619816f41f9fb3183774f630909 443 SUPERFAMILY SSF56112 3 332 7.69E-60 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_17530 ac6ee619816f41f9fb3183774f630909 443 Gene3D G3DSA:1.10.510.10 91 273 2.5E-44 T 12-10-2018 AFR_17530 ac6ee619816f41f9fb3183774f630909 443 Gene3D G3DSA:3.30.200.20 1 89 3.7E-20 T 12-10-2018 AFR_17530 ac6ee619816f41f9fb3183774f630909 443 PIRSF PIRSF000654 46 265 2.0E-18 T 12-10-2018 AFR_17530 ac6ee619816f41f9fb3183774f630909 443 Pfam PF00069 Protein kinase domain 10 256 3.3E-37 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_17530 ac6ee619816f41f9fb3183774f630909 443 SMART SM00220 5 266 4.2E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_17530 ac6ee619816f41f9fb3183774f630909 443 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 128 140 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 Pfam PF01467 Cytidylyltransferase-like 6 131 1.2E-20 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 59 8.1E-19 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 Gene3D G3DSA:3.40.50.620 1 158 2.7E-53 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 SUPERFAMILY SSF52374 1 153 9.98E-43 T 12-10-2018 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 74 0.007 T 12-10-2018 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 5.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 5.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 5.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 5.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 5.5E-50 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 34.008 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_36550 b914bd7b35f0100f3585452eab9cea7b 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 153 6.3E-57 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_03125 c73635b18317c93568eaabb60a80d491 281 SUPERFAMILY SSF51735 20 263 1.11E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03125 c73635b18317c93568eaabb60a80d491 281 PIRSF PIRSF000126 6 278 7.8E-51 T 12-10-2018 AFR_03125 c73635b18317c93568eaabb60a80d491 281 Pfam PF00106 short chain dehydrogenase 24 211 4.7E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03125 c73635b18317c93568eaabb60a80d491 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_03125 c73635b18317c93568eaabb60a80d491 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 22 206 0.0061 T 12-10-2018 AFR_03125 c73635b18317c93568eaabb60a80d491 281 Gene3D G3DSA:3.40.50.720 18 277 5.8E-56 T 12-10-2018 AFR_03125 c73635b18317c93568eaabb60a80d491 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 6.0E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03125 c73635b18317c93568eaabb60a80d491 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 6.0E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03125 c73635b18317c93568eaabb60a80d491 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 6.0E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03125 c73635b18317c93568eaabb60a80d491 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 6.0E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03125 c73635b18317c93568eaabb60a80d491 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 6.0E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_09685 385134fc4bc5ba514c95620367976c3e 287 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 219 235 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 AFR_09685 385134fc4bc5ba514c95620367976c3e 287 Hamap MF_00152 Probable endonuclease 4 [nfo]. 5 285 34.484 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 AFR_09685 385134fc4bc5ba514c95620367976c3e 287 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 179 186 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 AFR_09685 385134fc4bc5ba514c95620367976c3e 287 SMART SM00518 6 285 2.9E-65 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 AFR_09685 385134fc4bc5ba514c95620367976c3e 287 SUPERFAMILY SSF51658 7 283 5.5E-65 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_09685 385134fc4bc5ba514c95620367976c3e 287 Pfam PF01261 Xylose isomerase-like TIM barrel 27 243 4.9E-26 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_09685 385134fc4bc5ba514c95620367976c3e 287 Gene3D G3DSA:3.20.20.150 5 285 9.4E-70 T 12-10-2018 AFR_09685 385134fc4bc5ba514c95620367976c3e 287 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 7 282 2.3E-53 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 ProSitePatterns PS00756 Protein secY signature 2. 187 204 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 Gene3D G3DSA:1.10.3370.10 1 443 3.4E-163 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 447 29.025 T 12-10-2018 IPR026593 Protein translocase subunit SecY AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 443 3.0E-130 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 SUPERFAMILY SSF103491 2 438 1.12E-123 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 168 193 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 281 300 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 325 347 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 416 434 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 194 217 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 380 398 2.3E-85 T 12-10-2018 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 Pfam PF00344 SecY translocase 76 431 9.2E-118 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04605 cb1d345fcd9367bfda53a91b7e43333d 448 PIRSF PIRSF004557 1 448 2.1E-119 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 361 5.7E-117 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 Gene3D G3DSA:1.20.1050.90 120 317 3.8E-95 T 12-10-2018 AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 375 93.027 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 351 1.6E-20 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 ProSitePatterns PS00618 RecF protein signature 2. 318 336 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 Gene3D G3DSA:3.40.50.300 7 350 3.8E-95 T 12-10-2018 AFR_00020 659e57dd305a3bfdb3cceb173e60ef5c 375 SUPERFAMILY SSF52540 1 350 8.96E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09505 2aade94629b56019fe20ab9247388634 170 Pfam PF08281 Sigma-70, region 4 113 165 1.6E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_09505 2aade94629b56019fe20ab9247388634 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 169 4.9E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_09505 2aade94629b56019fe20ab9247388634 170 SUPERFAMILY SSF88946 1 102 1.02E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_09505 2aade94629b56019fe20ab9247388634 170 SUPERFAMILY SSF88659 106 169 7.85E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_09505 2aade94629b56019fe20ab9247388634 170 Pfam PF04542 Sigma-70 region 2 15 85 2.0E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_09505 2aade94629b56019fe20ab9247388634 170 Gene3D G3DSA:1.10.1740.10 1 81 9.4E-24 T 12-10-2018 AFR_09505 2aade94629b56019fe20ab9247388634 170 Gene3D G3DSA:1.10.10.10 104 170 2.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07770 f5035ae584490c4684f92ebc99ca0a60 805 SUPERFAMILY SSF48208 315 769 1.87E-8 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_07770 f5035ae584490c4684f92ebc99ca0a60 805 Gene3D G3DSA:1.20.1050.60 406 511 8.7E-225 T 12-10-2018 AFR_07770 f5035ae584490c4684f92ebc99ca0a60 805 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 39 791 1.7E-140 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_07770 f5035ae584490c4684f92ebc99ca0a60 805 Gene3D G3DSA:1.20.1610.10 512 666 8.7E-225 T 12-10-2018 AFR_07770 f5035ae584490c4684f92ebc99ca0a60 805 Gene3D G3DSA:2.70.98.10 44 405 8.7E-225 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_07770 f5035ae584490c4684f92ebc99ca0a60 805 Gene3D G3DSA:3.30.2080.10 351 790 8.7E-225 T 12-10-2018 AFR_07770 f5035ae584490c4684f92ebc99ca0a60 805 Pfam PF07971 Glycosyl hydrolase family 92 292 787 8.3E-155 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_13845 2c6ebe4f0f6f2cbe37244fb866098546 171 Gene3D G3DSA:1.10.10.60 1 41 4.5E-10 T 12-10-2018 AFR_13845 2c6ebe4f0f6f2cbe37244fb866098546 171 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 49 1.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13845 2c6ebe4f0f6f2cbe37244fb866098546 171 Pfam PF16859 Bacterial transcriptional repressor C-terminal 62 166 4.0E-18 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_13845 2c6ebe4f0f6f2cbe37244fb866098546 171 SUPERFAMILY SSF48498 63 170 2.2E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13845 2c6ebe4f0f6f2cbe37244fb866098546 171 Gene3D G3DSA:1.10.357.10 44 171 1.3E-18 T 12-10-2018 AFR_13845 2c6ebe4f0f6f2cbe37244fb866098546 171 SUPERFAMILY SSF46689 7 58 9.23E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_24350 f9c2a32b4e37fe384dfada68a2cc36a0 343 Pfam PF12872 OST-HTH/LOTUS domain 197 238 1.3E-4 T 12-10-2018 IPR025605 OST-HTH/LOTUS domain AFR_24350 f9c2a32b4e37fe384dfada68a2cc36a0 343 Pfam PF12872 OST-HTH/LOTUS domain 282 318 4.6E-4 T 12-10-2018 IPR025605 OST-HTH/LOTUS domain AFR_24350 f9c2a32b4e37fe384dfada68a2cc36a0 343 Gene3D G3DSA:3.40.50.1010 1 155 7.4E-34 T 12-10-2018 AFR_24350 f9c2a32b4e37fe384dfada68a2cc36a0 343 Pfam PF01936 NYN domain 6 152 3.5E-33 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Pfam PF00754 F5/8 type C domain 1010 1126 3.8E-23 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Pfam PF00754 F5/8 type C domain 173 285 3.8E-26 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Pfam PF00754 F5/8 type C domain 34 146 1.5E-27 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SUPERFAMILY SSF49785 31 151 3.69E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Gene3D G3DSA:2.60.120.260 1000 1130 6.5E-35 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Gene3D G3DSA:2.60.120.200 304 576 3.3E-60 T 12-10-2018 AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SUPERFAMILY SSF49899 303 574 1.19E-30 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Gene3D G3DSA:2.60.120.260 162 289 1.0E-38 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Gene3D G3DSA:2.60.120.260 25 151 6.0E-38 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 Gene3D G3DSA:3.20.20.80 595 896 1.1E-29 T 12-10-2018 AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SUPERFAMILY SSF51445 595 887 1.13E-34 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SUPERFAMILY SSF49785 167 289 4.11E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SUPERFAMILY SSF49785 995 1131 6.59E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SMART SM00231 161 286 0.19 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SMART SM00231 1001 1130 0.12 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32085 16e2f1b3f1feb06721d61076a416bf77 1132 SMART SM00231 20 152 0.013 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_34350 ac840500f55595cd324d0a0a4e764cf3 539 Gene3D G3DSA:1.20.58.1700 257 330 2.8E-138 T 12-10-2018 AFR_34350 ac840500f55595cd324d0a0a4e764cf3 539 Gene3D G3DSA:3.10.490.10 409 539 6.5E-44 T 12-10-2018 AFR_34350 ac840500f55595cd324d0a0a4e764cf3 539 SUPERFAMILY SSF75304 6 404 1.57E-99 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_34350 ac840500f55595cd324d0a0a4e764cf3 539 Pfam PF01425 Amidase 32 400 2.1E-70 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_34350 ac840500f55595cd324d0a0a4e764cf3 539 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 15 413 1.9E-155 T 12-10-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 AFR_34350 ac840500f55595cd324d0a0a4e764cf3 539 Gene3D G3DSA:3.90.1300.10 16 404 2.8E-138 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 Pfam PF00072 Response regulator receiver domain 11 119 6.8E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 SUPERFAMILY SSF46894 137 232 3.68E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 Gene3D G3DSA:1.10.10.10 138 235 3.7E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 231 2.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 SMART SM00862 160 231 3.2E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 SUPERFAMILY SSF52172 8 129 2.28E-41 T 12-10-2018 IPR011006 CheY-like superfamily AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 Gene3D G3DSA:3.40.50.2300 5 134 9.5E-38 T 12-10-2018 AFR_42440 f5fb6fd704d988491b196cf7a7c9eaeb 235 SMART SM00448 9 119 1.4E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_32795 e131e9ba3fa2202b54837eb89c7d1989 238 SUPERFAMILY SSF103473 37 231 1.94E-5 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 Pfam PF04539 Sigma-70 region 3 136 203 3.9E-9 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 SUPERFAMILY SSF88659 126 200 4.1E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 PRINTS PR00046 Major sigma-70 factor signature 222 234 8.6E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 PRINTS PR00046 Major sigma-70 factor signature 254 265 8.6E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 PRINTS PR00046 Major sigma-70 factor signature 77 90 8.6E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 PRINTS PR00046 Major sigma-70 factor signature 239 254 8.6E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 SUPERFAMILY SSF88946 36 122 1.37E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 48 269 1.3E-80 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 SUPERFAMILY SSF88659 194 269 7.29E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 Pfam PF04545 Sigma-70, region 4 218 266 1.7E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 Gene3D G3DSA:1.20.120.1810 8 121 1.5E-11 T 12-10-2018 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 Gene3D G3DSA:1.10.10.10 123 176 2.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 Gene3D G3DSA:1.10.10.10 193 271 1.2E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 Pfam PF04542 Sigma-70 region 2 54 122 2.8E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_16635 0cd4c5c1bb66f849b32158d676b9603f 272 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 269 5.3E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_29985 6a30a5e7f4cafed663ba1491bcd0dadf 327 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 10 234 7.1E-35 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFR_29985 6a30a5e7f4cafed663ba1491bcd0dadf 327 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 110 2.3E-22 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFR_29985 6a30a5e7f4cafed663ba1491bcd0dadf 327 Gene3D G3DSA:3.40.50.1000 8 237 3.7E-75 T 12-10-2018 IPR023214 HAD superfamily AFR_29985 6a30a5e7f4cafed663ba1491bcd0dadf 327 Gene3D G3DSA:3.40.50.1000 75 187 3.7E-75 T 12-10-2018 IPR023214 HAD superfamily AFR_29985 6a30a5e7f4cafed663ba1491bcd0dadf 327 SUPERFAMILY SSF56784 7 260 8.67E-55 T 12-10-2018 IPR036412 HAD-like superfamily AFR_29985 6a30a5e7f4cafed663ba1491bcd0dadf 327 PIRSF PIRSF000915 1 264 4.3E-57 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFR_29985 6a30a5e7f4cafed663ba1491bcd0dadf 327 Pfam PF13242 HAD-hyrolase-like 187 258 2.8E-17 T 12-10-2018 AFR_41370 67dd9a99acd06a0bf3ca6a8dcb4b45b8 253 Gene3D G3DSA:3.30.420.40 87 253 1.6E-53 T 12-10-2018 AFR_41370 67dd9a99acd06a0bf3ca6a8dcb4b45b8 253 Gene3D G3DSA:3.30.420.40 1 85 1.8E-23 T 12-10-2018 AFR_41370 67dd9a99acd06a0bf3ca6a8dcb4b45b8 253 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 253 32.687 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFR_41370 67dd9a99acd06a0bf3ca6a8dcb4b45b8 253 Pfam PF03309 Type III pantothenate kinase 2 203 9.0E-66 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFR_41370 67dd9a99acd06a0bf3ca6a8dcb4b45b8 253 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 248 8.3E-68 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFR_41370 67dd9a99acd06a0bf3ca6a8dcb4b45b8 253 SUPERFAMILY SSF53067 2 120 2.05E-32 T 12-10-2018 AFR_41370 67dd9a99acd06a0bf3ca6a8dcb4b45b8 253 SUPERFAMILY SSF53067 122 252 7.18E-33 T 12-10-2018 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 Gene3D G3DSA:1.10.287.130 105 175 7.4E-20 T 12-10-2018 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 SUPERFAMILY SSF55874 168 340 4.19E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 261 275 5.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 321 5.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 339 5.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 Pfam PF00512 His Kinase A (phospho-acceptor) domain 113 179 1.2E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 Gene3D G3DSA:3.30.565.10 176 341 1.0E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 SMART SM00388 112 179 1.7E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 SMART SM00387 224 342 1.9E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 SUPERFAMILY SSF47384 101 179 2.16E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_23470 0f7a32165b7d6a1a24e9d41792457ab1 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 226 340 1.2E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 82 1.9E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 SUPERFAMILY SSF46785 14 91 1.43E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 Pfam PF07729 FCD domain 111 232 4.2E-23 T 12-10-2018 IPR011711 GntR, C-terminal AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 Gene3D G3DSA:1.20.120.530 107 240 3.4E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 1.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 1.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 Gene3D G3DSA:1.10.10.10 13 87 2.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 SMART SM00895 111 234 6.8E-18 T 12-10-2018 IPR011711 GntR, C-terminal AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 SUPERFAMILY SSF48008 110 238 4.18E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_29085 8da040fd9668ee2dbb328f7b2e2dc6a4 251 SMART SM00345 23 82 2.5E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_00315 8f873a4ab08bece5baf1a9ecbdaf62ec 231 Pfam PF05949 Bacterial protein of unknown function (DUF881) 77 227 4.2E-39 T 12-10-2018 IPR010273 Protein of unknown function DUF881 AFR_00315 8f873a4ab08bece5baf1a9ecbdaf62ec 231 Gene3D G3DSA:3.30.70.1880 74 231 2.5E-28 T 12-10-2018 AFR_27930 022b0ca7bfbb9f938a2b3a144230265b 579 SUPERFAMILY SSF56112 26 300 8.7E-74 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_27930 022b0ca7bfbb9f938a2b3a144230265b 579 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 148 160 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_27930 022b0ca7bfbb9f938a2b3a144230265b 579 SMART SM00220 29 289 2.1E-74 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_27930 022b0ca7bfbb9f938a2b3a144230265b 579 Gene3D G3DSA:1.10.510.10 23 287 1.9E-69 T 12-10-2018 AFR_27930 022b0ca7bfbb9f938a2b3a144230265b 579 Pfam PF00069 Protein kinase domain 34 277 8.3E-52 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_27930 022b0ca7bfbb9f938a2b3a144230265b 579 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 35 58 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_32075 00d4ff42809de1a92de18de07f54517e 413 Pfam PF04542 Sigma-70 region 2 11 77 3.9E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_32075 00d4ff42809de1a92de18de07f54517e 413 SUPERFAMILY SSF88659 101 160 6.54E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_32075 00d4ff42809de1a92de18de07f54517e 413 Pfam PF08281 Sigma-70, region 4 108 157 1.1E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_32075 00d4ff42809de1a92de18de07f54517e 413 Gene3D G3DSA:1.10.1740.10 2 81 1.1E-5 T 12-10-2018 AFR_32075 00d4ff42809de1a92de18de07f54517e 413 Gene3D G3DSA:1.10.10.10 114 162 8.2E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32075 00d4ff42809de1a92de18de07f54517e 413 SUPERFAMILY SSF88946 4 74 9.42E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_37550 cdedc11807221f5c624ded54275bb0aa 258 SUPERFAMILY SSF47413 28 78 6.52E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_37550 cdedc11807221f5c624ded54275bb0aa 258 Gene3D G3DSA:3.30.450.180 98 251 1.0E-13 T 12-10-2018 AFR_37550 cdedc11807221f5c624ded54275bb0aa 258 Gene3D G3DSA:1.10.260.40 4 83 6.3E-9 T 12-10-2018 AFR_37550 cdedc11807221f5c624ded54275bb0aa 258 Pfam PF13560 Helix-turn-helix domain 5 83 1.2E-16 T 12-10-2018 AFR_37550 cdedc11807221f5c624ded54275bb0aa 258 SMART SM00530 8 80 1.3E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 SUPERFAMILY SSF58104 96 389 1.31E-60 T 12-10-2018 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 Gene3D G3DSA:1.10.287.950 76 391 5.9E-60 T 12-10-2018 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 209 357 4.1E-30 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 234 261 7.1E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 263 292 7.1E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 55 75 7.1E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 SMART SM00283 136 390 8.6E-43 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 SMART SM00304 76 128 4.1E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_11075 0ceafcfbe98730015a0f50c77010f3fa 391 Pfam PF00672 HAMP domain 90 124 2.4E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 100 120 1.3E-11 T 12-10-2018 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 393 412 1.3E-11 T 12-10-2018 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 155 179 1.3E-11 T 12-10-2018 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 154 1.3E-11 T 12-10-2018 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 1.3E-11 T 12-10-2018 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 Gene3D G3DSA:1.20.1720.10 7 211 1.9E-48 T 12-10-2018 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 8 418 2.2E-81 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_30830 656cf4280bde94512e2685a31e56a97b 509 SUPERFAMILY SSF103473 2 492 2.75E-64 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_30830 656cf4280bde94512e2685a31e56a97b 509 Pfam PF07690 Major Facilitator Superfamily 10 402 3.0E-54 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 37 92 2.9E-12 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 SUPERFAMILY SSF56801 36 616 9.29E-121 T 12-10-2018 AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 5 640 1.7E-234 T 12-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 Gene3D G3DSA:3.40.50.12780 68 508 4.0E-61 T 12-10-2018 AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 ProSitePatterns PS00455 Putative AMP-binding domain signature. 260 271 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 Pfam PF00501 AMP-binding enzyme 103 513 6.5E-50 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 Gene3D G3DSA:3.30.300.30 511 635 2.4E-12 T 12-10-2018 AFR_05620 90f6fded24e2f26fa0abfc97f2209a0d 641 Pfam PF13193 AMP-binding enzyme C-terminal domain 526 600 4.6E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_40460 1d190b48704f41b09d3565f22259f2ad 315 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 214 242 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 AFR_40460 1d190b48704f41b09d3565f22259f2ad 315 Gene3D G3DSA:1.10.530.10 160 314 3.5E-43 T 12-10-2018 AFR_40460 1d190b48704f41b09d3565f22259f2ad 315 Pfam PF00877 NlpC/P60 family 59 153 4.5E-21 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_40460 1d190b48704f41b09d3565f22259f2ad 315 Pfam PF01464 Transglycosylase SLT domain 196 301 2.2E-30 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFR_40460 1d190b48704f41b09d3565f22259f2ad 315 Gene3D G3DSA:3.90.1720.10 7 159 6.8E-43 T 12-10-2018 AFR_40460 1d190b48704f41b09d3565f22259f2ad 315 SUPERFAMILY SSF54001 41 159 5.4E-35 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_40460 1d190b48704f41b09d3565f22259f2ad 315 SUPERFAMILY SSF53955 190 311 7.32E-43 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_15160 b60dcfa92edfa0840f38a2e061331688 359 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 158 338 8.9E-13 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_15160 b60dcfa92edfa0840f38a2e061331688 359 SUPERFAMILY SSF55846 133 350 1.28E-25 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_15160 b60dcfa92edfa0840f38a2e061331688 359 Gene3D G3DSA:3.40.80.10 129 354 7.5E-37 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_15160 b60dcfa92edfa0840f38a2e061331688 359 SMART SM00701 133 293 7.3E-6 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_41945 879ee49664f53702e0d1c99aeac279e2 925 Pfam PF00672 HAMP domain 320 386 7.5E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_41945 879ee49664f53702e0d1c99aeac279e2 925 SUPERFAMILY SSF55874 489 609 3.01E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41945 879ee49664f53702e0d1c99aeac279e2 925 SMART SM00304 320 390 0.0041 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_41945 879ee49664f53702e0d1c99aeac279e2 925 Gene3D G3DSA:3.30.565.10 470 612 7.2E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41945 879ee49664f53702e0d1c99aeac279e2 925 Pfam PF08376 Nitrate and nitrite sensing 58 222 6.2E-12 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein AFR_41945 879ee49664f53702e0d1c99aeac279e2 925 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 507 608 8.8E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_41945 879ee49664f53702e0d1c99aeac279e2 925 SMART SM00387 502 612 9.3E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 46 63 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 43 64 1.5E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 136 153 1.5E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 97 1.5E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 111 127 1.5E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 8 293 55.648 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 12 287 4.1E-76 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 141 171 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 SMART SM01130 8 295 4.7E-114 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 Pfam PF00701 Dihydrodipicolinate synthetase family 9 290 6.1E-81 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 PIRSF PIRSF001365 6 300 2.2E-75 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 Gene3D G3DSA:3.20.20.70 1 296 1.2E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_35845 cb04f3eaf4009a2cf50540021633d46e 301 SUPERFAMILY SSF51569 8 294 2.51E-89 T 12-10-2018 AFR_41775 e854d1697f62dc66a177395876e3da83 345 SUPERFAMILY SSF52540 5 254 2.83E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41775 e854d1697f62dc66a177395876e3da83 345 SMART SM00382 41 233 2.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41775 e854d1697f62dc66a177395876e3da83 345 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_41775 e854d1697f62dc66a177395876e3da83 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 327 1.2E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_41775 e854d1697f62dc66a177395876e3da83 345 Pfam PF00005 ABC transporter 33 183 8.6E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_41775 e854d1697f62dc66a177395876e3da83 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 304 3.0E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_41775 e854d1697f62dc66a177395876e3da83 345 Gene3D G3DSA:3.40.50.300 3 339 9.0E-100 T 12-10-2018 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 Gene3D G3DSA:3.30.70.20 423 486 4.9E-11 T 12-10-2018 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 SUPERFAMILY SSF54862 427 485 5.02E-8 T 12-10-2018 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 321 398 1.3E-15 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 Pfam PF13459 4Fe-4S single cluster domain 428 483 1.6E-10 T 12-10-2018 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 53 210 5.9E-28 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 SUPERFAMILY SSF140490 313 409 6.41E-15 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 Gene3D G3DSA:3.40.50.11540 56 223 3.9E-36 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 SMART SM00928 317 362 2.7E-4 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 SUPERFAMILY SSF142984 235 308 5.89E-7 T 12-10-2018 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 Gene3D G3DSA:1.20.1440.230 313 410 1.3E-7 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 SUPERFAMILY SSF142019 35 232 6.93E-35 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27245 6117785035a15584c3d66f40efe38ecb 490 Gene3D G3DSA:3.10.20.600 224 312 2.0E-7 T 12-10-2018 AFR_22665 51d979b13bf7bcec814cc4e176e32a25 282 Pfam PF01040 UbiA prenyltransferase family 26 200 1.1E-12 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFR_22665 51d979b13bf7bcec814cc4e176e32a25 282 Gene3D G3DSA:1.10.357.140 17 163 1.1E-11 T 12-10-2018 AFR_18225 9b7d4574ffa151b222f22383176d6de8 297 SUPERFAMILY SSF161098 64 281 1.7E-44 T 12-10-2018 IPR035906 MetI-like superfamily AFR_18225 9b7d4574ffa151b222f22383176d6de8 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 289 4.5E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_18225 9b7d4574ffa151b222f22383176d6de8 297 Gene3D G3DSA:1.10.3720.10 60 295 1.6E-47 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13110 b362effbc0edae41beac25b84703ba3e 423 Pfam PF13347 MFS/sugar transport protein 64 365 1.3E-23 T 12-10-2018 AFR_13110 b362effbc0edae41beac25b84703ba3e 423 Gene3D G3DSA:1.20.1250.20 22 217 2.0E-16 T 12-10-2018 AFR_13110 b362effbc0edae41beac25b84703ba3e 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 298 315 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_13110 b362effbc0edae41beac25b84703ba3e 423 Gene3D G3DSA:1.20.1250.20 236 422 1.5E-26 T 12-10-2018 AFR_13110 b362effbc0edae41beac25b84703ba3e 423 SUPERFAMILY SSF103473 15 421 1.22E-48 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_32165 888e30fb2ce706e8d2fa62dadb8c0263 140 ProDom PD011053 BIOSYNTHESIS PHENAZINE PROBABLE PHZA PHZB ANTIBIOTIC VIRULENCE A/B EHPA PHZ1 42 133 1.0E-6 T 12-10-2018 IPR004964 Phenazine biosynthesis protein A/B GO:0017000 AFR_32165 888e30fb2ce706e8d2fa62dadb8c0263 140 Gene3D G3DSA:3.10.450.50 2 133 2.3E-38 T 12-10-2018 AFR_32165 888e30fb2ce706e8d2fa62dadb8c0263 140 SUPERFAMILY SSF54427 4 132 1.78E-31 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_32165 888e30fb2ce706e8d2fa62dadb8c0263 140 Pfam PF12680 SnoaL-like domain 9 116 6.6E-13 T 12-10-2018 IPR037401 SnoaL-like domain AFR_12400 c4f6a533ef406cf08c7899918493fc9d 525 SMART SM00637 425 524 1.9E-36 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_12400 c4f6a533ef406cf08c7899918493fc9d 525 Gene3D G3DSA:2.60.40.290 419 525 4.8E-30 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_12400 c4f6a533ef406cf08c7899918493fc9d 525 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 61 364 3.8E-65 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AFR_12400 c4f6a533ef406cf08c7899918493fc9d 525 Gene3D G3DSA:3.20.20.80 37 395 1.6E-119 T 12-10-2018 AFR_12400 c4f6a533ef406cf08c7899918493fc9d 525 SUPERFAMILY SSF49384 420 524 8.37E-27 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_12400 c4f6a533ef406cf08c7899918493fc9d 525 Pfam PF00553 Cellulose binding domain 430 524 5.7E-25 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_12400 c4f6a533ef406cf08c7899918493fc9d 525 SUPERFAMILY SSF51445 1 395 4.7E-79 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 SMART SM00267 439 604 5.5E-56 T 12-10-2018 IPR000160 GGDEF domain AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 SMART SM00091 337 403 3.1E-12 T 12-10-2018 IPR000014 PAS domain AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 SUPERFAMILY SSF55785 329 437 4.05E-21 T 12-10-2018 IPR035965 PAS domain superfamily AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 Pfam PF00990 Diguanylate cyclase, GGDEF domain 450 599 1.2E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 Pfam PF00989 PAS fold 338 390 4.3E-9 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 334 446 1.7E-16 T 12-10-2018 IPR000014 PAS domain AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 448 602 2.7E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 SUPERFAMILY SSF55073 455 602 4.79E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 Gene3D G3DSA:3.30.70.270 451 604 1.6E-48 T 12-10-2018 AFR_21895 b968be1ec32b27627fb6b55ac8ee5414 605 Gene3D G3DSA:3.30.450.20 334 450 1.5E-20 T 12-10-2018 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 205 2.7E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 SMART SM00448 2 112 3.8E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 SUPERFAMILY SSF46894 143 213 5.78E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 SUPERFAMILY SSF52172 1 131 1.99E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 Pfam PF00072 Response regulator receiver domain 1 113 1.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 Gene3D G3DSA:3.40.50.12740 1 212 1.1E-68 T 12-10-2018 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 SMART SM00421 149 206 7.6E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24835 4c383489e13b65ff5701186671cfcd8c 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 SUPERFAMILY SSF50952 13 369 4.84E-23 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 Gene3D G3DSA:2.60.40.1220 886 980 3.0E-11 T 12-10-2018 AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 Gene3D G3DSA:2.120.10.30 7 391 6.6E-64 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 Pfam PF13205 Bacterial Ig-like domain 875 980 5.8E-27 T 12-10-2018 IPR032812 SbsA, Ig-like domain AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 Gene3D G3DSA:2.60.40.10 441 534 1.4E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 SUPERFAMILY SSF49299 433 531 8.89E-17 T 12-10-2018 IPR035986 PKD domain superfamily AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 Pfam PF00801 PKD domain 454 524 2.4E-11 T 12-10-2018 IPR000601 PKD domain AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 SMART SM00089 449 535 3.3E-15 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_13925 f947f04d1d9cc451b1004c5a019c65e5 1133 Pfam PF07995 Glucose / Sorbosone dehydrogenase 29 342 5.1E-30 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_10455 577b66863962fb5d8b02004614492d8b 506 SUPERFAMILY SSF50249 280 368 1.0E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_10455 577b66863962fb5d8b02004614492d8b 506 Gene3D G3DSA:2.40.50.140 287 371 6.7E-29 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 Gene3D G3DSA:2.40.50.140 121 202 1.5E-9 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 Gene3D G3DSA:2.40.50.140 26 120 4.9E-23 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 SUPERFAMILY SSF50249 31 133 4.4E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_10455 577b66863962fb5d8b02004614492d8b 506 SUPERFAMILY SSF50249 210 293 1.24E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_10455 577b66863962fb5d8b02004614492d8b 506 Pfam PF00575 S1 RNA binding domain 294 366 5.1E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_10455 577b66863962fb5d8b02004614492d8b 506 Pfam PF00575 S1 RNA binding domain 126 191 4.0E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_10455 577b66863962fb5d8b02004614492d8b 506 Pfam PF00575 S1 RNA binding domain 36 108 8.5E-15 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_10455 577b66863962fb5d8b02004614492d8b 506 Pfam PF00575 S1 RNA binding domain 208 280 5.6E-26 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_10455 577b66863962fb5d8b02004614492d8b 506 Gene3D G3DSA:2.40.50.140 207 286 1.7E-30 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 SUPERFAMILY SSF50249 111 194 1.07E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 232 253 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 105 124 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 129 145 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 39 57 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 146 163 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 349 367 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 310 329 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 175 195 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 PRINTS PR00681 Ribosomal protein S1 signature 57 71 1.8E-86 T 12-10-2018 AFR_10455 577b66863962fb5d8b02004614492d8b 506 SMART SM00316 124 191 4.2E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_10455 577b66863962fb5d8b02004614492d8b 506 SMART SM00316 37 108 1.8E-16 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_10455 577b66863962fb5d8b02004614492d8b 506 SMART SM00316 210 280 4.8E-28 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_10455 577b66863962fb5d8b02004614492d8b 506 SMART SM00316 295 366 3.0E-24 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 Gene3D G3DSA:3.30.499.20 10 302 1.4E-98 T 12-10-2018 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 SUPERFAMILY SSF53732 7 479 6.28E-166 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 ProSitePatterns PS01244 Aconitase family signature 2. 415 428 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 Pfam PF00330 Aconitase family (aconitate hydratase) 13 473 5.2E-161 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 8 476 1.5E-226 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 ProSitePatterns PS00450 Aconitase family signature 1. 355 371 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 225 238 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 415 428 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 359 370 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 98 111 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 211 224 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 302 316 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 135 148 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 149 164 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 PRINTS PR00415 Aconitase family signature 124 132 1.2E-47 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 7 481 57.687 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFR_36695 36009f2ca955912a87b74ed47448e74a 481 Gene3D G3DSA:3.30.499.10 344 481 2.6E-48 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AFR_17110 34879a5ecdaf27fc4dd0a4f3582efdeb 261 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 12 234 6.1E-24 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_17110 34879a5ecdaf27fc4dd0a4f3582efdeb 261 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 147 1.6E-15 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_17110 34879a5ecdaf27fc4dd0a4f3582efdeb 261 SUPERFAMILY SSF109854 6 152 2.98E-17 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_17110 34879a5ecdaf27fc4dd0a4f3582efdeb 261 Gene3D G3DSA:1.20.120.450 2 152 6.8E-19 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_35085 14e8a468cf0bf66db291e2e0fdc90743 413 Gene3D G3DSA:3.30.565.10 288 410 1.5E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_35085 14e8a468cf0bf66db291e2e0fdc90743 413 Pfam PF07730 Histidine kinase 212 277 2.8E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_35085 14e8a468cf0bf66db291e2e0fdc90743 413 SUPERFAMILY SSF55874 291 410 6.25E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 Gene3D G3DSA:3.40.50.720 1 259 4.8E-78 T 12-10-2018 AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 257 6.2E-60 T 12-10-2018 AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 186 0.0012 T 12-10-2018 AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 SUPERFAMILY SSF51735 15 258 6.54E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 4.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 4.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 4.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 4.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 4.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13515 a081dfa04b87215f93bda8c79ccf1e24 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 4.1E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 16 420 3.0E-181 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 338 418 2.7E-30 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 174 189 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 SUPERFAMILY SSF142019 12 246 1.1E-88 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 348 359 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 SUPERFAMILY SSF140490 332 425 2.48E-35 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 Gene3D G3DSA:3.10.20.600 239 331 1.1E-26 T 12-10-2018 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 SUPERFAMILY SSF142984 249 330 8.63E-21 T 12-10-2018 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 Pfam PF10531 SLBB domain 251 297 1.1E-6 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 Gene3D G3DSA:1.20.1440.230 335 432 2.9E-30 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 SMART SM00928 335 380 3.2E-24 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 Gene3D G3DSA:3.40.50.11540 60 238 6.9E-79 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01680 785022fa133bb44cf6cb6fdd84b82687 438 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 55 226 1.5E-47 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_22810 3b981f0000f0b67767c6920c407c5f77 214 SUPERFAMILY SSF52172 1 163 3.98E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_22810 3b981f0000f0b67767c6920c407c5f77 214 SMART SM00448 1 108 6.2E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_22810 3b981f0000f0b67767c6920c407c5f77 214 Pfam PF00486 Transcriptional regulatory protein, C terminal 142 209 2.8E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_22810 3b981f0000f0b67767c6920c407c5f77 214 SMART SM00862 142 209 2.0E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_22810 3b981f0000f0b67767c6920c407c5f77 214 Pfam PF00072 Response regulator receiver domain 1 108 1.9E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_22810 3b981f0000f0b67767c6920c407c5f77 214 Gene3D G3DSA:1.10.10.10 118 211 3.5E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22810 3b981f0000f0b67767c6920c407c5f77 214 Gene3D G3DSA:3.40.50.2300 1 117 7.1E-30 T 12-10-2018 AFR_30485 1bfd6e1dbad12b138e9c3e92b8891503 291 SUPERFAMILY SSF53850 35 281 2.48E-46 T 12-10-2018 AFR_30485 1bfd6e1dbad12b138e9c3e92b8891503 291 SMART SM00062 56 284 1.4E-24 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_30485 1bfd6e1dbad12b138e9c3e92b8891503 291 SMART SM00079 56 283 0.0011 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AFR_30485 1bfd6e1dbad12b138e9c3e92b8891503 291 Gene3D G3DSA:3.40.190.10 146 243 1.8E-41 T 12-10-2018 AFR_30485 1bfd6e1dbad12b138e9c3e92b8891503 291 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 57 281 5.7E-42 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_30485 1bfd6e1dbad12b138e9c3e92b8891503 291 Gene3D G3DSA:3.40.190.10 54 273 1.8E-41 T 12-10-2018 AFR_33875 7143c77990447d4f711a6a1990f2979c 255 Gene3D G3DSA:3.40.50.300 2 246 1.0E-54 T 12-10-2018 AFR_33875 7143c77990447d4f711a6a1990f2979c 255 SMART SM00382 31 226 9.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33875 7143c77990447d4f711a6a1990f2979c 255 Pfam PF00005 ABC transporter 23 178 1.3E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_33875 7143c77990447d4f711a6a1990f2979c 255 SUPERFAMILY SSF52540 6 230 1.18E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25475 c646779b245e22c029deea73f273ee9d 463 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 310 373 2.6E-7 T 12-10-2018 AFR_25475 c646779b245e22c029deea73f273ee9d 463 SUPERFAMILY SSF69318 190 439 6.15E-26 T 12-10-2018 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 1.0E-189 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 Gene3D G3DSA:2.40.30.10 209 302 4.1E-31 T 12-10-2018 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 Gene3D G3DSA:3.40.50.300 1 205 1.8E-64 T 12-10-2018 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 Pfam PF03143 Elongation factor Tu C-terminal domain 300 393 2.6E-23 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 4.5E-55 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 Gene3D G3DSA:2.40.30.10 303 393 8.2E-33 T 12-10-2018 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 147 9.8E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.3E-22 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 PRINTS PR00315 GTP-binding elongation factor signature 133 142 3.3E-22 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.3E-22 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 PRINTS PR00315 GTP-binding elongation factor signature 80 90 3.3E-22 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 PRINTS PR00315 GTP-binding elongation factor signature 96 107 3.3E-22 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 SUPERFAMILY SSF50465 300 394 3.45E-26 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 SUPERFAMILY SSF52540 6 220 1.18E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.7E-12 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 55.069 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 SUPERFAMILY SSF50447 207 303 1.1E-25 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_32430 a934ce630601fdbdb138d78b78bcae19 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_42070 b6185411c88f6174fc7cb08cbacc015c 78 Pfam PF04149 Domain of unknown function (DUF397) 17 69 2.1E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_23230 149c3d2d9578de14b45779e8b783d079 216 SMART SM01120 33 207 9.6E-61 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_23230 149c3d2d9578de14b45779e8b783d079 216 Pfam PF02734 DAK2 domain 34 205 3.4E-50 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_23230 149c3d2d9578de14b45779e8b783d079 216 SUPERFAMILY SSF101473 13 207 1.19E-49 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_23230 149c3d2d9578de14b45779e8b783d079 216 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 13 205 5.1E-53 T 12-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 AFR_23230 149c3d2d9578de14b45779e8b783d079 216 Gene3D G3DSA:1.25.40.340 8 210 1.4E-59 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_33485 9effa7d6e9663f6617fd15654cddbef7 194 Pfam PF01794 Ferric reductase like transmembrane component 15 137 6.5E-12 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain AFR_41500 42fa1534b3541d818a0fdecb906d134b 371 Gene3D G3DSA:2.70.70.10 201 368 1.1E-35 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_41500 42fa1534b3541d818a0fdecb906d134b 371 Pfam PF01551 Peptidase family M23 239 347 6.6E-23 T 12-10-2018 IPR016047 Peptidase M23 AFR_41500 42fa1534b3541d818a0fdecb906d134b 371 SUPERFAMILY SSF51261 224 360 4.5E-33 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_18790 347cc675775763c39c8a8e655cb8211a 110 Pfam PF07883 Cupin domain 28 89 3.5E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_18790 347cc675775763c39c8a8e655cb8211a 110 SUPERFAMILY SSF51182 10 98 6.82E-17 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_18790 347cc675775763c39c8a8e655cb8211a 110 Gene3D G3DSA:2.60.120.10 2 105 6.0E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_09490 a2f1b8b92d6b3a99a0c112c42d6965a6 375 Pfam PF00534 Glycosyl transferases group 1 189 354 1.4E-37 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_09490 a2f1b8b92d6b3a99a0c112c42d6965a6 375 Gene3D G3DSA:3.40.50.2000 5 362 5.3E-115 T 12-10-2018 AFR_09490 a2f1b8b92d6b3a99a0c112c42d6965a6 375 SUPERFAMILY SSF53756 5 372 4.71E-68 T 12-10-2018 AFR_09490 a2f1b8b92d6b3a99a0c112c42d6965a6 375 Gene3D G3DSA:3.40.50.2000 169 361 5.3E-115 T 12-10-2018 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 SMART SM00418 23 103 2.4E-30 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 Gene3D G3DSA:1.10.10.10 7 106 5.9E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08325 d08037684f5deaf08830b7867a7a3898 110 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 49 67 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 Pfam PF01022 Bacterial regulatory protein, arsR family 30 78 2.8E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 58 1.4E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.4E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.4E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 25 40 1.4E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08325 d08037684f5deaf08830b7867a7a3898 110 SUPERFAMILY SSF46785 4 102 1.12E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 305 72.167 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 2.0E-25 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 2.0E-25 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 2.0E-25 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 2.0E-25 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 6.5E-24 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 6.5E-24 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 6.5E-24 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 6.5E-24 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 6.5E-24 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 304 6.9E-105 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 141 8.8E-40 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 Gene3D G3DSA:3.40.50.1370 131 291 6.5E-112 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 302 3.4E-52 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 SUPERFAMILY SSF53671 2 304 3.01E-95 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFR_30225 1aa01e93cf2da4ae7f675ac271591479 309 Gene3D G3DSA:3.40.50.1370 9 300 6.5E-112 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFR_04030 d82a0b1b229a19e69060b60dd09afe12 240 Pfam PF02254 TrkA-N domain 29 144 1.9E-22 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFR_04030 d82a0b1b229a19e69060b60dd09afe12 240 SUPERFAMILY SSF51735 27 157 4.04E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_04030 d82a0b1b229a19e69060b60dd09afe12 240 SUPERFAMILY SSF116726 154 237 2.35E-14 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_04030 d82a0b1b229a19e69060b60dd09afe12 240 Pfam PF02080 TrkA-C domain 173 239 6.2E-11 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFR_04030 d82a0b1b229a19e69060b60dd09afe12 240 Gene3D G3DSA:3.40.50.720 25 160 8.6E-32 T 12-10-2018 AFR_04030 d82a0b1b229a19e69060b60dd09afe12 240 Gene3D G3DSA:3.30.70.1450 161 238 5.5E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_24085 e549e32c55b919e7a093e3290d0b78ca 249 Pfam PF00501 AMP-binding enzyme 18 89 3.8E-6 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_24085 e549e32c55b919e7a093e3290d0b78ca 249 Gene3D G3DSA:3.40.50.12780 22 249 1.0E-8 T 12-10-2018 AFR_24085 e549e32c55b919e7a093e3290d0b78ca 249 SUPERFAMILY SSF56801 17 247 1.26E-15 T 12-10-2018 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 Gene3D G3DSA:3.40.50.2300 1 105 5.2E-17 T 12-10-2018 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 SUPERFAMILY SSF52172 1 133 1.24E-22 T 12-10-2018 IPR011006 CheY-like superfamily AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 Pfam PF00072 Response regulator receiver domain 3 106 1.7E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 SUPERFAMILY SSF46894 133 195 1.67E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 SMART SM00421 146 203 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 Gene3D G3DSA:1.10.10.10 106 212 2.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 194 8.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33945 d43fcc3b9016b4d66379b60ff255f729 213 SMART SM00448 1 118 4.3E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40120 4d1598e6cbdcac3b4f450713deefba85 125 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 25 124 4.3E-29 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_40120 4d1598e6cbdcac3b4f450713deefba85 125 Gene3D G3DSA:1.20.58.1610 3 125 3.0E-32 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 26 302 3.6E-47 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 25 306 8.5E-77 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 Gene3D G3DSA:3.30.590.20 20 381 2.7E-105 T 12-10-2018 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 SUPERFAMILY SSF55931 22 379 2.35E-89 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 Pfam PF14403 Circularly permuted ATP-grasp type 2 468 842 2.1E-128 T 12-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 Gene3D G3DSA:3.30.1490.270 739 798 6.7E-17 T 12-10-2018 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 SUPERFAMILY SSF56059 443 855 1.27E-40 T 12-10-2018 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 434 71.578 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_33185 68efdb97cc04d5a30979fb3111f7056e 864 Gene3D G3DSA:3.40.50.11290 606 702 3.4E-21 T 12-10-2018 AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 Gene3D G3DSA:3.30.70.270 298 463 3.1E-45 T 12-10-2018 AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 Pfam PF00990 Diguanylate cyclase, GGDEF domain 304 454 1.0E-35 T 12-10-2018 IPR000160 GGDEF domain AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 302 456 6.4E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 SMART SM00267 293 458 2.3E-49 T 12-10-2018 IPR000160 GGDEF domain AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 Gene3D G3DSA:3.20.20.450 470 733 1.2E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 SUPERFAMILY SSF141868 473 721 1.14E-78 T 12-10-2018 IPR035919 EAL domain superfamily AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 SMART SM00052 468 714 6.6E-91 T 12-10-2018 IPR001633 EAL domain AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 Pfam PF00563 EAL domain 474 707 1.6E-68 T 12-10-2018 IPR001633 EAL domain AFR_36900 018746829d2dc55f470d7ddf42caec8b 794 SUPERFAMILY SSF55073 309 459 8.63E-39 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_35815 5c5be9e9516b1d1cfc49e1b2b8ac122f 471 Pfam PF09594 Glycosyltransferase family 87 60 293 5.0E-7 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 AFR_01030 35cd8aefa4fafb786141462b1b05bcc5 196 Gene3D G3DSA:1.10.357.10 6 194 9.0E-36 T 12-10-2018 AFR_01030 35cd8aefa4fafb786141462b1b05bcc5 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 93 191 1.2E-6 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_01030 35cd8aefa4fafb786141462b1b05bcc5 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01030 35cd8aefa4fafb786141462b1b05bcc5 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01030 35cd8aefa4fafb786141462b1b05bcc5 196 SUPERFAMILY SSF48498 78 191 9.27E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_01030 35cd8aefa4fafb786141462b1b05bcc5 196 SUPERFAMILY SSF46689 7 80 1.69E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01030 35cd8aefa4fafb786141462b1b05bcc5 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.7E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12425 00b41eaaf0750a11e6251bd76beb9a12 70 SUPERFAMILY SSF160582 4 66 1.83E-26 T 12-10-2018 IPR038020 MbtH-like domain superfamily AFR_12425 00b41eaaf0750a11e6251bd76beb9a12 70 Pfam PF03621 MbtH-like protein 4 50 9.4E-22 T 12-10-2018 IPR005153 MbtH-like domain AFR_12425 00b41eaaf0750a11e6251bd76beb9a12 70 SMART SM00923 1 50 1.3E-19 T 12-10-2018 IPR005153 MbtH-like domain AFR_12425 00b41eaaf0750a11e6251bd76beb9a12 70 Gene3D G3DSA:3.90.820.10 1 68 7.2E-29 T 12-10-2018 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 Pfam PF00553 Cellulose binding domain 783 876 7.4E-22 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 Gene3D G3DSA:2.130.10.10 51 457 3.0E-297 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 SMART SM00637 783 878 6.3E-29 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 SUPERFAMILY SSF110296 42 441 2.62E-81 T 12-10-2018 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 SUPERFAMILY SSF49384 778 877 4.53E-25 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 SUPERFAMILY SSF110296 449 755 1.46E-43 T 12-10-2018 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 Gene3D G3DSA:2.60.40.290 777 882 1.2E-26 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_18920 78fcff9191677947dc4a58fc3d222fb6 882 Gene3D G3DSA:2.130.10.10 42 751 3.0E-297 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_24445 80a1d752f294e9b4876f70397f5f5f70 266 SUPERFAMILY SSF53335 8 199 2.25E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_24445 80a1d752f294e9b4876f70397f5f5f70 266 Gene3D G3DSA:3.40.50.150 23 232 1.5E-24 T 12-10-2018 AFR_24445 80a1d752f294e9b4876f70397f5f5f70 266 Pfam PF08241 Methyltransferase domain 49 139 3.6E-11 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_04275 aade8fbb5036a8eb96eaf4e9e30659cb 488 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 5 483 14.306 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFR_04275 aade8fbb5036a8eb96eaf4e9e30659cb 488 Pfam PF00361 Proton-conducting membrane transporter 123 412 3.9E-48 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 SUPERFAMILY SSF51735 3 231 1.97E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 1.7E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 1.7E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.7E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.7E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.7E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 Pfam PF00106 short chain dehydrogenase 3 183 6.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 Gene3D G3DSA:3.40.50.720 2 240 6.4E-61 T 12-10-2018 AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34780 2f014270c59ddb5e3cb05dc4db28c23c 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10685 9800ff25bdba567d0312333c7ee0041f 409 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 7 408 4.3E-175 T 12-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFR_10685 9800ff25bdba567d0312333c7ee0041f 409 Gene3D G3DSA:3.90.1150.10 8 400 5.6E-170 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_10685 9800ff25bdba567d0312333c7ee0041f 409 SUPERFAMILY SSF53383 3 405 8.11E-130 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_10685 9800ff25bdba567d0312333c7ee0041f 409 Gene3D G3DSA:3.40.640.10 36 297 5.6E-170 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_10685 9800ff25bdba567d0312333c7ee0041f 409 Pfam PF00266 Aminotransferase class-V 25 397 1.9E-144 T 12-10-2018 IPR000192 Aminotransferase class V domain AFR_40355 2c6f35fc1511408f6b940e243bb56750 270 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 8 109 1.5E-10 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 AFR_40355 2c6f35fc1511408f6b940e243bb56750 270 Gene3D G3DSA:3.30.530.20 1 141 8.3E-26 T 12-10-2018 IPR023393 START-like domain superfamily AFR_40355 2c6f35fc1511408f6b940e243bb56750 270 SUPERFAMILY SSF55961 3 134 5.5E-17 T 12-10-2018 AFR_40820 7ce02bc7f22099481742f0974a4f5863 684 SMART SM00491 521 650 1.1E-34 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFR_40820 7ce02bc7f22099481742f0974a4f5863 684 SMART SM00487 35 331 0.0024 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_40820 7ce02bc7f22099481742f0974a4f5863 684 SUPERFAMILY SSF52540 51 644 9.25E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40820 7ce02bc7f22099481742f0974a4f5863 684 Pfam PF13307 Helicase C-terminal domain 503 662 5.7E-30 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFR_40820 7ce02bc7f22099481742f0974a4f5863 684 Gene3D G3DSA:3.40.50.300 38 301 9.0E-43 T 12-10-2018 AFR_40820 7ce02bc7f22099481742f0974a4f5863 684 Gene3D G3DSA:3.40.50.300 493 675 4.4E-32 T 12-10-2018 AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 Pfam PF13229 Right handed beta helix region 238 345 8.3E-7 T 12-10-2018 IPR039448 Right handed beta helix domain AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 Gene3D G3DSA:2.60.40.290 32 134 2.3E-28 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 Gene3D G3DSA:2.160.20.10 157 477 1.2E-25 T 12-10-2018 IPR012334 Pectin lyase fold AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 Pfam PF00553 Cellulose binding domain 34 130 6.4E-26 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 SUPERFAMILY SSF51126 164 469 3.31E-22 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 SMART SM00637 33 130 5.4E-33 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 98 111 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 SMART SM00710 268 290 22.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 SMART SM00710 292 320 240.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 SMART SM00710 246 267 3100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 SMART SM00710 391 412 3000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_40250 9ebe8e56a863e9931db4836d74dbb924 478 SUPERFAMILY SSF49384 33 131 1.81E-25 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_01655 365f3ec49ed8120194c29fe1df8618d0 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 121 19.09 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 AFR_01655 365f3ec49ed8120194c29fe1df8618d0 121 Gene3D G3DSA:1.20.58.1610 1 121 3.8E-40 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01655 365f3ec49ed8120194c29fe1df8618d0 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 120 4.8E-35 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_26075 7a8354ccfd21ead02daaa43837854c1b 414 SUPERFAMILY SSF53850 33 392 8.15E-49 T 12-10-2018 AFR_26075 7a8354ccfd21ead02daaa43837854c1b 414 Gene3D G3DSA:3.40.190.10 151 396 1.9E-57 T 12-10-2018 AFR_26075 7a8354ccfd21ead02daaa43837854c1b 414 Gene3D G3DSA:3.40.190.10 55 367 1.9E-57 T 12-10-2018 AFR_26075 7a8354ccfd21ead02daaa43837854c1b 414 Pfam PF13416 Bacterial extracellular solute-binding protein 70 354 2.4E-20 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_38400 7618b80129ed7f62a5cacaec8fe163e3 437 SUPERFAMILY SSF63411 12 221 4.82E-46 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_38400 7618b80129ed7f62a5cacaec8fe163e3 437 SUPERFAMILY SSF63411 237 432 1.08E-19 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_38400 7618b80129ed7f62a5cacaec8fe163e3 437 Gene3D G3DSA:3.30.830.10 236 437 3.4E-30 T 12-10-2018 AFR_38400 7618b80129ed7f62a5cacaec8fe163e3 437 Pfam PF00675 Insulinase (Peptidase family M16) 27 143 6.0E-18 T 12-10-2018 IPR011765 Peptidase M16, N-terminal AFR_38400 7618b80129ed7f62a5cacaec8fe163e3 437 Pfam PF05193 Peptidase M16 inactive domain 183 366 5.1E-22 T 12-10-2018 IPR007863 Peptidase M16, C-terminal AFR_38400 7618b80129ed7f62a5cacaec8fe163e3 437 Gene3D G3DSA:3.30.830.10 11 232 4.8E-57 T 12-10-2018 AFR_41165 8366f64afd53e8b25fe409056aecd933 360 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 355 2.1E-93 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFR_41165 8366f64afd53e8b25fe409056aecd933 360 Gene3D G3DSA:3.90.1150.10 10 351 1.1E-122 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_41165 8366f64afd53e8b25fe409056aecd933 360 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 359 46.718 T 12-10-2018 IPR024892 Putative phenylalanine aminotransferase AFR_41165 8366f64afd53e8b25fe409056aecd933 360 SUPERFAMILY SSF53383 15 353 2.15E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_41165 8366f64afd53e8b25fe409056aecd933 360 Gene3D G3DSA:3.40.640.10 45 270 1.1E-122 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_41165 8366f64afd53e8b25fe409056aecd933 360 Pfam PF00155 Aminotransferase class I and II 33 351 6.4E-52 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_41165 8366f64afd53e8b25fe409056aecd933 360 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 358 51.798 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFR_41165 8366f64afd53e8b25fe409056aecd933 360 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 222 231 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFR_28550 1576238848e52799f781384d6bb6b115 317 Pfam PF14525 AraC-binding-like domain 24 176 3.7E-20 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_28550 1576238848e52799f781384d6bb6b115 317 SMART SM00342 210 292 3.9E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_28550 1576238848e52799f781384d6bb6b115 317 SUPERFAMILY SSF46689 245 292 1.25E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_28550 1576238848e52799f781384d6bb6b115 317 Gene3D G3DSA:1.10.10.60 190 305 6.5E-23 T 12-10-2018 AFR_28550 1576238848e52799f781384d6bb6b115 317 Pfam PF12833 Helix-turn-helix domain 216 290 3.0E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_00970 4ee8e736e8344225bb0f0e83696a8fe7 257 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 103 238 9.4E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_00970 4ee8e736e8344225bb0f0e83696a8fe7 257 Gene3D G3DSA:1.10.10.60 28 91 3.2E-20 T 12-10-2018 AFR_00970 4ee8e736e8344225bb0f0e83696a8fe7 257 SUPERFAMILY SSF46689 33 92 1.59E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_00970 4ee8e736e8344225bb0f0e83696a8fe7 257 SUPERFAMILY SSF48498 101 247 3.11E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_00970 4ee8e736e8344225bb0f0e83696a8fe7 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 2.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_00970 4ee8e736e8344225bb0f0e83696a8fe7 257 Gene3D G3DSA:1.10.357.10 100 244 7.5E-28 T 12-10-2018 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 SUPERFAMILY SSF55785 17 128 3.49E-18 T 12-10-2018 IPR035965 PAS domain superfamily AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 SMART SM00091 6 71 1.0E-4 T 12-10-2018 IPR000014 PAS domain AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 Gene3D G3DSA:3.40.50.2300 394 515 4.5E-25 T 12-10-2018 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 4 128 1.2E-15 T 12-10-2018 IPR000014 PAS domain AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 Pfam PF00989 PAS fold 11 118 2.5E-10 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 SMART SM00387 257 377 1.1E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 SUPERFAMILY SSF47384 137 214 1.96E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 258 375 1.6E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 Gene3D G3DSA:3.30.450.20 4 124 2.1E-22 T 12-10-2018 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 Gene3D G3DSA:3.30.565.10 219 382 8.3E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 SMART SM00448 396 509 3.3E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 SUPERFAMILY SSF55874 206 375 2.23E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 SUPERFAMILY SSF52172 395 514 3.13E-26 T 12-10-2018 IPR011006 CheY-like superfamily AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 374 1.8E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 334 1.8E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 320 1.8E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 355 1.8E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 Gene3D G3DSA:1.10.287.130 139 214 1.7E-16 T 12-10-2018 AFR_07715 77907dd9d7a7c032ec304674e545e6b7 515 Pfam PF00072 Response regulator receiver domain 399 509 1.0E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_29220 f895a3e9a386ca04186c4677f6198051 584 Gene3D G3DSA:3.40.50.300 345 584 4.7E-88 T 12-10-2018 AFR_29220 f895a3e9a386ca04186c4677f6198051 584 Pfam PF00005 ABC transporter 369 516 9.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_29220 f895a3e9a386ca04186c4677f6198051 584 Pfam PF00664 ABC transporter transmembrane region 31 303 2.7E-41 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_29220 f895a3e9a386ca04186c4677f6198051 584 SMART SM00382 376 562 2.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_29220 f895a3e9a386ca04186c4677f6198051 584 SUPERFAMILY SSF52540 342 582 3.35E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29220 f895a3e9a386ca04186c4677f6198051 584 SUPERFAMILY SSF90123 11 336 5.1E-69 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_29220 f895a3e9a386ca04186c4677f6198051 584 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_29220 f895a3e9a386ca04186c4677f6198051 584 Gene3D G3DSA:1.20.1560.10 3 336 1.5E-78 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 SUPERFAMILY SSF55073 384 531 2.67E-33 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 Pfam PF00563 EAL domain 553 787 1.1E-71 T 12-10-2018 IPR001633 EAL domain AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 SMART SM00267 368 537 2.0E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 Gene3D G3DSA:3.30.70.270 376 533 6.6E-41 T 12-10-2018 AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 Pfam PF01590 GAF domain 233 366 6.1E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 SMART SM00065 230 376 2.5E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 SUPERFAMILY SSF55781 210 375 5.89E-15 T 12-10-2018 AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 SMART SM00052 547 792 5.9E-100 T 12-10-2018 IPR001633 EAL domain AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 SUPERFAMILY SSF141868 554 799 7.06E-83 T 12-10-2018 IPR035919 EAL domain superfamily AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 Gene3D G3DSA:3.20.20.450 548 810 1.2E-93 T 12-10-2018 IPR035919 EAL domain superfamily AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 Pfam PF00990 Diguanylate cyclase, GGDEF domain 379 529 1.8E-31 T 12-10-2018 IPR000160 GGDEF domain AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 Gene3D G3DSA:3.30.450.40 207 375 5.9E-18 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_04400 a5cbb51bc055265a16b4dda24f343b3c 818 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 377 529 8.2E-26 T 12-10-2018 IPR000160 GGDEF domain AFR_21735 628423c2a5620f7b6fa118a48b4df6c0 186 Gene3D G3DSA:3.40.50.1240 11 182 2.3E-25 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_21735 628423c2a5620f7b6fa118a48b4df6c0 186 PIRSF PIRSF000709 16 182 6.5E-4 T 12-10-2018 AFR_21735 628423c2a5620f7b6fa118a48b4df6c0 186 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 22 180 3.1E-25 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_21735 628423c2a5620f7b6fa118a48b4df6c0 186 SUPERFAMILY SSF53254 17 180 1.01E-28 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 SUPERFAMILY SSF49899 323 567 7.55E-72 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 Gene3D G3DSA:2.60.120.200 327 567 1.6E-87 T 12-10-2018 AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 SUPERFAMILY SSF49785 175 308 1.35E-24 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 Gene3D G3DSA:2.60.120.260 29 160 8.8E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 SUPERFAMILY SSF49785 35 155 9.22E-27 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 Pfam PF00754 F5/8 type C domain 185 302 4.5E-20 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 Pfam PF00754 F5/8 type C domain 38 142 1.1E-21 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 Gene3D G3DSA:2.60.120.260 175 308 1.3E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33795 8712a01711ab9022f89cc7372a747e5b 567 Pfam PF00722 Glycosyl hydrolases family 16 361 564 1.2E-33 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_23380 60814dbfa155074e363d742c6ca005f7 121 SUPERFAMILY SSF52091 33 118 1.94E-9 T 12-10-2018 IPR036513 STAS domain superfamily AFR_23380 60814dbfa155074e363d742c6ca005f7 121 Pfam PF13466 STAS domain 40 114 2.4E-10 T 12-10-2018 IPR002645 STAS domain AFR_23380 60814dbfa155074e363d742c6ca005f7 121 Gene3D G3DSA:3.30.750.24 22 121 2.6E-13 T 12-10-2018 IPR036513 STAS domain superfamily AFR_11825 ce63ac797ddd51b02b09568b66cb0aa2 210 Pfam PF13302 Acetyltransferase (GNAT) domain 16 165 1.5E-14 T 12-10-2018 IPR000182 GNAT domain AFR_11825 ce63ac797ddd51b02b09568b66cb0aa2 210 Gene3D G3DSA:3.40.630.30 5 209 1.7E-47 T 12-10-2018 AFR_11825 ce63ac797ddd51b02b09568b66cb0aa2 210 SUPERFAMILY SSF55729 7 191 9.07E-37 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 SMART SM00344 3 110 1.5E-37 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 Gene3D G3DSA:3.30.70.920 55 147 9.7E-16 T 12-10-2018 AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 SUPERFAMILY SSF46785 2 63 1.45E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 SUPERFAMILY SSF54909 64 143 6.57E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 6.0E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 Gene3D G3DSA:1.10.10.10 4 54 2.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 Pfam PF01037 Lrp/AsnC ligand binding domain 82 140 1.9E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_42615 b3c668b3e0b8084eba9d6a0e8e532b62 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 74 748 9.6E-252 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 SUPERFAMILY SSF56024 571 751 6.5E-63 T 12-10-2018 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 SUPERFAMILY SSF56024 384 567 3.11E-57 T 12-10-2018 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 PIRSF PIRSF015589 54 755 7.4E-275 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 Gene3D G3DSA:3.30.1840.10 67 378 2.5E-113 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 SUPERFAMILY SSF140356 72 175 1.83E-34 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 Pfam PF13090 Polyphosphate kinase C-terminal domain 400 747 2.9E-150 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 Pfam PF02503 Polyphosphate kinase middle domain 190 389 2.9E-69 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 SUPERFAMILY SSF143724 178 379 2.94E-64 T 12-10-2018 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 Pfam PF13089 Polyphosphate kinase N-terminal domain 75 181 1.8E-35 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 Gene3D G3DSA:3.30.870.10 385 570 1.2E-73 T 12-10-2018 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 Hamap MF_00347 Polyphosphate kinase [ppk]. 72 753 28.619 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFR_36670 52d9e57eac2beb1f52cfbac0a31c9519 756 Gene3D G3DSA:3.30.870.10 571 754 2.7E-60 T 12-10-2018 AFR_08700 e9810d9e22a21359b30cb84bc4591e8a 319 SUPERFAMILY SSF52151 2 303 1.23E-57 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_08700 e9810d9e22a21359b30cb84bc4591e8a 319 Gene3D G3DSA:3.30.70.250 122 185 4.0E-76 T 12-10-2018 AFR_08700 e9810d9e22a21359b30cb84bc4591e8a 319 SUPERFAMILY SSF55048 124 176 3.27E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding AFR_08700 e9810d9e22a21359b30cb84bc4591e8a 319 Pfam PF00698 Acyl transferase domain 37 276 3.4E-14 T 12-10-2018 IPR014043 Acyl transferase AFR_08700 e9810d9e22a21359b30cb84bc4591e8a 319 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 293 1.2E-13 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain AFR_08700 e9810d9e22a21359b30cb84bc4591e8a 319 Gene3D G3DSA:3.40.366.10 3 275 4.0E-76 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 SUPERFAMILY SSF52540 11 152 2.78E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 Gene3D G3DSA:1.25.40.10 583 819 1.1E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 Pfam PF13191 AAA ATPase domain 3 138 1.1E-16 T 12-10-2018 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 SUPERFAMILY SSF46894 824 883 4.08E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 846 862 5.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 862 874 5.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 832 846 5.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 Pfam PF00196 Bacterial regulatory proteins, luxR family 831 882 1.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 SUPERFAMILY SSF48452 357 795 7.59E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 SMART SM00421 829 886 3.4E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23050 edf7c783f4f064244d54f0bedcac70ab 890 Gene3D G3DSA:1.10.10.10 824 888 6.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08150 981184a31d5f8a77ea09b1b576417aa8 166 Pfam PF14332 Domain of unknown function (DUF4388) 3 143 7.0E-6 T 12-10-2018 IPR025497 Domain of unknown function DUF4388 AFR_27605 e32c12ca879428f9ecc57b555ee008c3 308 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 7 35 5.4E-5 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFR_27605 e32c12ca879428f9ecc57b555ee008c3 308 SUPERFAMILY SSF51658 50 292 1.61E-35 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_27605 e32c12ca879428f9ecc57b555ee008c3 308 Pfam PF01261 Xylose isomerase-like TIM barrel 71 246 8.8E-15 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_27605 e32c12ca879428f9ecc57b555ee008c3 308 Gene3D G3DSA:3.20.20.150 42 308 7.8E-66 T 12-10-2018 AFR_14290 6b815a3a48e4e40fbfe4a9e23e9b8856 445 Pfam PF06965 Na+/H+ antiporter 1 26 405 2.5E-131 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_14290 6b815a3a48e4e40fbfe4a9e23e9b8856 445 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 23 414 20.689 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_14290 6b815a3a48e4e40fbfe4a9e23e9b8856 445 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 27 404 2.1E-94 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_14290 6b815a3a48e4e40fbfe4a9e23e9b8856 445 Gene3D G3DSA:1.20.1530.10 20 413 9.6E-138 T 12-10-2018 IPR023171 Na/H antiporter domain superfamily AFR_22515 a2b9ecbb0a03f13e1d58825c320463b4 251 SUPERFAMILY SSF53335 21 218 9.05E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_22515 a2b9ecbb0a03f13e1d58825c320463b4 251 Pfam PF08241 Methyltransferase domain 44 136 7.6E-19 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_22515 a2b9ecbb0a03f13e1d58825c320463b4 251 Gene3D G3DSA:3.40.50.150 13 249 2.4E-39 T 12-10-2018 AFR_05060 210254d771cea1ddc57f4f63009634fd 96 SMART SM00830 25 86 1.9E-8 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_05060 210254d771cea1ddc57f4f63009634fd 96 SUPERFAMILY SSF48600 20 79 5.49E-13 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_05060 210254d771cea1ddc57f4f63009634fd 96 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 20 94 2.1E-21 T 12-10-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal AFR_05060 210254d771cea1ddc57f4f63009634fd 96 Pfam PF01817 Chorismate mutase type II 25 80 3.9E-10 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_05060 210254d771cea1ddc57f4f63009634fd 96 Gene3D G3DSA:1.20.59.10 12 96 5.6E-23 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFR_25780 806903cee45775dddc7168b4f22c7789 272 Gene3D G3DSA:3.20.20.370 84 269 3.5E-27 T 12-10-2018 AFR_25780 806903cee45775dddc7168b4f22c7789 272 SUPERFAMILY SSF88713 73 266 1.81E-29 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_25780 806903cee45775dddc7168b4f22c7789 272 Pfam PF01522 Polysaccharide deacetylase 89 208 7.2E-23 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 Gene3D G3DSA:1.10.10.60 205 314 3.2E-24 T 12-10-2018 AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 Pfam PF12833 Helix-turn-helix domain 232 309 6.4E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 Pfam PF14525 AraC-binding-like domain 20 191 2.1E-7 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 SUPERFAMILY SSF46689 262 312 3.45E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 305 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 SMART SM00342 226 309 3.7E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 309 3.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_11850 2e20d3592bdb028d09c928b84e6d92f0 326 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 293 3.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 253 6.9E-64 T 12-10-2018 AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 193 0.0075 T 12-10-2018 AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 SUPERFAMILY SSF51735 10 254 4.54E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 Gene3D G3DSA:3.40.50.720 1 254 2.1E-84 T 12-10-2018 AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.5E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.5E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.5E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.5E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.5E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.5E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.5E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.5E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.5E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17170 bbee700680d7a9c0db9cb31767e6e149 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_34835 13127bbfc95e1830d87d762f789e9084 230 PIRSF PIRSF029755 1 230 1.0E-113 T 12-10-2018 IPR016938 Uncharacterised protein family UPF0317 AFR_34835 13127bbfc95e1830d87d762f789e9084 230 SUPERFAMILY SSF160920 2 223 1.44E-105 T 12-10-2018 IPR038021 Putative hydro-lyase AFR_34835 13127bbfc95e1830d87d762f789e9084 230 Hamap MF_01830 Putative hydro-lyase . 1 230 48.907 T 12-10-2018 IPR016938 Uncharacterised protein family UPF0317 AFR_34835 13127bbfc95e1830d87d762f789e9084 230 Pfam PF07286 Protein of unknown function (DUF1445) 80 222 9.2E-68 T 12-10-2018 IPR009906 D-glutamate cyclase AFR_34835 13127bbfc95e1830d87d762f789e9084 230 Gene3D G3DSA:3.40.1640.10 2 218 2.4E-91 T 12-10-2018 AFR_34835 13127bbfc95e1830d87d762f789e9084 230 Gene3D G3DSA:3.30.2040.10 90 202 2.4E-91 T 12-10-2018 AFR_25285 7deda406a746d6d5ff6c914844600a57 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 309 1.4E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_25285 7deda406a746d6d5ff6c914844600a57 325 SUPERFAMILY SSF160964 34 92 3.27E-6 T 12-10-2018 AFR_25285 7deda406a746d6d5ff6c914844600a57 325 SUPERFAMILY SSF161098 79 307 2.75E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_25285 7deda406a746d6d5ff6c914844600a57 325 Gene3D G3DSA:1.10.3720.10 75 315 2.8E-63 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 1.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 1.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 1.2E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 SUPERFAMILY SSF55874 290 448 2.23E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 SUPERFAMILY SSF158472 181 230 2.62E-7 T 12-10-2018 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 SUPERFAMILY SSF47384 219 301 6.08E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 439 2.0E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 301 1.9E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 SMART SM00304 181 234 3.5E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 SMART SM00388 235 301 5.2E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 SMART SM00387 345 452 1.7E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 Gene3D G3DSA:1.10.287.130 185 301 1.3E-25 T 12-10-2018 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 Pfam PF00672 HAMP domain 183 230 2.8E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_11445 e4ba85ca7f8160dd0df4669440e016d8 452 Gene3D G3DSA:3.30.565.10 311 451 1.5E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28205 c5cbda6a40f8f6b1fab71ff5845114cd 318 Gene3D G3DSA:3.40.50.300 6 203 1.8E-43 T 12-10-2018 AFR_28205 c5cbda6a40f8f6b1fab71ff5845114cd 318 SUPERFAMILY SSF52540 23 284 4.37E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28205 c5cbda6a40f8f6b1fab71ff5845114cd 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 1.3E-61 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_28205 c5cbda6a40f8f6b1fab71ff5845114cd 318 Gene3D G3DSA:1.10.8.300 204 308 2.4E-30 T 12-10-2018 AFR_28205 c5cbda6a40f8f6b1fab71ff5845114cd 318 PIRSF PIRSF002849 2 314 2.3E-125 T 12-10-2018 AFR_13560 139b064bba31338292c0ed90271f4b7c 414 Gene3D G3DSA:1.10.10.2840 274 402 8.5E-31 T 12-10-2018 AFR_13560 139b064bba31338292c0ed90271f4b7c 414 Pfam PF13556 PucR C-terminal helix-turn-helix domain 341 397 1.8E-18 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 573 3.3E-275 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 SUPERFAMILY SSF100920 356 512 3.14E-58 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 SUPERFAMILY SSF53067 3 159 4.86E-58 T 12-10-2018 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 441 457 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 360 379 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 337 357 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 306 322 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 174 184 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 PRINTS PR00301 70kDa heat shock protein signature 114 134 3.7E-78 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 Gene3D G3DSA:3.90.640.10 200 287 9.3E-144 T 12-10-2018 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 309 323 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 Gene3D G3DSA:3.30.420.40 5 348 9.3E-144 T 12-10-2018 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 Gene3D G3DSA:2.60.34.10 349 476 1.3E-57 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 Gene3D G3DSA:1.20.1270.10 479 579 1.6E-26 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 629 35.922 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 SUPERFAMILY SSF53067 162 354 7.66E-65 T 12-10-2018 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 Gene3D G3DSA:3.30.420.40 162 337 9.3E-144 T 12-10-2018 AFR_00520 0be2342cb77eb12154ea26c073aadedb 632 Pfam PF00012 Hsp70 protein 78 574 6.3E-215 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_41785 34e9915c38aa3b6edbab0eb0c094f423 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 330 2.4E-37 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_41785 34e9915c38aa3b6edbab0eb0c094f423 332 SUPERFAMILY SSF161098 107 316 4.03E-17 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41785 34e9915c38aa3b6edbab0eb0c094f423 332 Gene3D G3DSA:1.10.3720.10 102 324 6.1E-21 T 12-10-2018 IPR035906 MetI-like superfamily AFR_06325 1494c89f772584ec69c6f7cf76027428 96 Gene3D G3DSA:3.30.1390.10 5 92 7.5E-18 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFR_06325 1494c89f772584ec69c6f7cf76027428 96 SUPERFAMILY SSF54736 19 94 1.62E-24 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFR_06325 1494c89f772584ec69c6f7cf76027428 96 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 10 96 15.577 T 12-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS AFR_06325 1494c89f772584ec69c6f7cf76027428 96 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 21 91 5.6E-21 T 12-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 AFR_10000 6df3ac7251087e2a36be67b9fc6dc598 367 Pfam PF00953 Glycosyl transferase family 4 91 284 7.9E-33 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 AFR_10000 6df3ac7251087e2a36be67b9fc6dc598 367 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10000 6df3ac7251087e2a36be67b9fc6dc598 367 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 1.5E-5 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10000 6df3ac7251087e2a36be67b9fc6dc598 367 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 16 355 3.4E-86 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10000 6df3ac7251087e2a36be67b9fc6dc598 367 ProSitePatterns PS01348 MraY family signature 2. 184 195 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10000 6df3ac7251087e2a36be67b9fc6dc598 367 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 359 21.999 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 SUPERFAMILY SSF54211 229 400 1.9E-53 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 196 209 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 321 337 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 181 196 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 228 250 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 252 270 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 383 403 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 603 615 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 369 383 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 479 488 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR01159 DNA gyrase subunit B signature 619 635 1.7E-72 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 SUPERFAMILY SSF55874 8 211 4.06E-67 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Pfam PF00204 DNA gyrase B 229 399 2.3E-60 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 650 2.1E-284 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 SMART SM00433 37 643 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Gene3D G3DSA:3.30.565.10 4 217 1.1E-79 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Gene3D G3DSA:3.40.50.670 407 650 2.7E-98 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 SUPERFAMILY SSF56719 403 645 3.92E-84 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 175 4.0E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 ProSitePatterns PS00177 DNA topoisomerase II signature. 431 439 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 495 511 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 429 443 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 513 530 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 533 545 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 72 85 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 278 291 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 115 129 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 582 598 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 PRINTS PR00418 DNA topoisomerase II family signature 37 52 3.1E-68 T 12-10-2018 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Gene3D G3DSA:3.30.230.10 227 406 3.0E-68 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Pfam PF01751 Toprim domain 428 536 2.1E-16 T 12-10-2018 IPR006171 TOPRIM domain AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 650 87.733 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 581 639 3.3E-26 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_00040 3b9b85f2af965b4461c0fd69508db388 650 SMART SM00387 33 176 2.8E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_39235 fd293063c964d293731245d59069ad5c 220 SUPERFAMILY SSF144091 28 205 1.7E-26 T 12-10-2018 AFR_39235 fd293063c964d293731245d59069ad5c 220 Pfam PF01694 Rhomboid family 69 202 9.5E-23 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AFR_39235 fd293063c964d293731245d59069ad5c 220 Gene3D G3DSA:1.20.1540.10 69 206 3.7E-19 T 12-10-2018 IPR035952 Rhomboid-like superfamily AFR_27715 b470e08fc930c96efc13fbb61f759c7a 117 Gene3D G3DSA:1.10.10.10 1 76 2.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27715 b470e08fc930c96efc13fbb61f759c7a 117 SMART SM00345 16 75 3.2E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_27715 b470e08fc930c96efc13fbb61f759c7a 117 SUPERFAMILY SSF46785 4 79 8.81E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27715 b470e08fc930c96efc13fbb61f759c7a 117 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 1.9E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_22445 a1ebfb2c47d95ed9d7435f902dee31aa 430 Pfam PF13416 Bacterial extracellular solute-binding protein 54 355 6.8E-29 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_22445 a1ebfb2c47d95ed9d7435f902dee31aa 430 SUPERFAMILY SSF53850 17 426 2.28E-70 T 12-10-2018 AFR_22445 a1ebfb2c47d95ed9d7435f902dee31aa 430 Gene3D G3DSA:3.40.190.10 62 385 1.3E-69 T 12-10-2018 AFR_22445 a1ebfb2c47d95ed9d7435f902dee31aa 430 Gene3D G3DSA:3.40.190.10 157 412 1.3E-69 T 12-10-2018 AFR_31830 1ae33e1c6ff879bfafe1a37ae13364b8 116 Pfam PF11774 Lsr2 1 113 7.4E-39 T 12-10-2018 IPR024412 Lsr2 AFR_31830 1ae33e1c6ff879bfafe1a37ae13364b8 116 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 114 8.0E-23 T 12-10-2018 IPR024412 Lsr2 AFR_31830 1ae33e1c6ff879bfafe1a37ae13364b8 116 Gene3D G3DSA:1.20.890.50 80 116 4.0E-13 T 12-10-2018 AFR_31830 1ae33e1c6ff879bfafe1a37ae13364b8 116 Gene3D G3DSA:3.30.60.230 1 59 7.1E-25 T 12-10-2018 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 1.1E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 Gene3D G3DSA:3.40.50.2300 61 312 2.2E-73 T 12-10-2018 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 Gene3D G3DSA:1.10.260.40 2 60 8.7E-20 T 12-10-2018 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 SUPERFAMILY SSF47413 4 60 8.94E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 SMART SM00354 2 72 9.9E-22 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 Gene3D G3DSA:3.40.50.2300 159 293 2.2E-73 T 12-10-2018 AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 SUPERFAMILY SSF53822 63 330 5.3E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_26310 8ca270063f4346fc5339c30693c8b5b0 331 Pfam PF13377 Periplasmic binding protein-like domain 169 329 6.6E-33 T 12-10-2018 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Pfam PF00391 PEP-utilising enzyme, mobile domain 799 870 4.4E-19 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Gene3D G3DSA:3.30.1490.20 65 152 8.2E-32 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Gene3D G3DSA:3.30.1490.20 19 64 7.2E-9 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 SUPERFAMILY SSF52009 769 874 5.36E-25 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Gene3D G3DSA:3.30.470.20 203 253 6.0E-7 T 12-10-2018 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Gene3D G3DSA:3.30.470.20 153 202 5.5E-12 T 12-10-2018 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 SUPERFAMILY SSF56059 26 256 2.12E-67 T 12-10-2018 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 66 200 1.9E-43 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 28 60 4.1E-6 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFR_16715 465ec59da31a3045a70ed2d4f6fdfd35 886 Gene3D G3DSA:3.50.30.10 772 877 4.1E-29 T 12-10-2018 AFR_37585 9a155f8cda54fffede977ac36eb1273b 417 Pfam PF00999 Sodium/hydrogen exchanger family 13 400 4.0E-44 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_37585 9a155f8cda54fffede977ac36eb1273b 417 Gene3D G3DSA:1.20.1530.20 7 407 7.9E-86 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFR_05000 6b56938558ea44c894126e0254b4e855 291 Gene3D G3DSA:1.20.120.1760 79 248 8.2E-12 T 12-10-2018 AFR_05000 6b56938558ea44c894126e0254b4e855 291 Pfam PF01066 CDP-alcohol phosphatidyltransferase 81 143 2.3E-11 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_05000 6b56938558ea44c894126e0254b4e855 291 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 121 143 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 Pfam PF00989 PAS fold 186 294 1.4E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 SUPERFAMILY SSF141868 480 726 1.96E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 181 304 7.8E-14 T 12-10-2018 IPR000014 PAS domain AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 SMART SM00091 183 249 2.3E-6 T 12-10-2018 IPR000014 PAS domain AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 SMART SM00052 472 720 1.7E-116 T 12-10-2018 IPR001633 EAL domain AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 Gene3D G3DSA:3.20.20.450 477 733 4.1E-101 T 12-10-2018 IPR035919 EAL domain superfamily AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 SMART SM00267 297 462 3.7E-58 T 12-10-2018 IPR000160 GGDEF domain AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 Pfam PF00990 Diguanylate cyclase, GGDEF domain 308 457 3.1E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 Pfam PF00563 EAL domain 480 715 1.8E-74 T 12-10-2018 IPR001633 EAL domain AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 305 461 5.7E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 Gene3D G3DSA:3.30.70.270 302 476 4.0E-55 T 12-10-2018 AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 Gene3D G3DSA:3.30.450.20 169 294 3.5E-17 T 12-10-2018 AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 SUPERFAMILY SSF55785 171 294 5.15E-17 T 12-10-2018 IPR035965 PAS domain superfamily AFR_20850 6a897ea9e161a3e0cfbc1729aab96b1d 736 SUPERFAMILY SSF55073 313 464 2.83E-46 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_26735 f15c7ff2075d96e829d140d1f3b17a09 262 SUPERFAMILY SSF56752 15 243 1.31E-32 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFR_26735 f15c7ff2075d96e829d140d1f3b17a09 262 Gene3D G3DSA:3.30.470.10 7 105 2.4E-6 T 12-10-2018 AFR_26735 f15c7ff2075d96e829d140d1f3b17a09 262 Pfam PF01063 Amino-transferase class IV 25 235 2.7E-21 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFR_26735 f15c7ff2075d96e829d140d1f3b17a09 262 Gene3D G3DSA:3.20.10.10 113 258 6.3E-19 T 12-10-2018 AFR_36295 385ed4bcd580b52a499f221f393b7e23 148 Pfam PF00293 NUDIX domain 6 129 2.0E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_36295 385ed4bcd580b52a499f221f393b7e23 148 PRINTS PR00502 NUDIX hydrolase family signature 50 65 7.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_36295 385ed4bcd580b52a499f221f393b7e23 148 PRINTS PR00502 NUDIX hydrolase family signature 36 50 7.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_36295 385ed4bcd580b52a499f221f393b7e23 148 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_36295 385ed4bcd580b52a499f221f393b7e23 148 SUPERFAMILY SSF55811 6 130 2.57E-21 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_36295 385ed4bcd580b52a499f221f393b7e23 148 Gene3D G3DSA:3.90.79.10 2 137 2.4E-24 T 12-10-2018 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Gene3D G3DSA:3.40.50.261 503 604 4.1E-8 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Gene3D G3DSA:3.40.50.261 311 468 1.9E-47 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Pfam PF13549 ATP-grasp domain 629 825 1.3E-53 T 12-10-2018 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Gene3D G3DSA:3.30.1490.20 640 709 1.6E-61 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Gene3D G3DSA:3.30.470.20 629 822 1.6E-61 T 12-10-2018 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 SUPERFAMILY SSF51735 178 316 4.38E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Gene3D G3DSA:3.40.630.30 1 183 2.3E-53 T 12-10-2018 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 SUPERFAMILY SSF52210 464 596 1.44E-13 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Pfam PF00583 Acetyltransferase (GNAT) family 38 143 6.6E-12 T 12-10-2018 IPR000182 GNAT domain AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 SUPERFAMILY SSF52210 309 470 4.19E-36 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 SUPERFAMILY SSF56059 629 819 1.15E-30 T 12-10-2018 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 SUPERFAMILY SSF55729 7 149 5.83E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 333 462 8.0E-40 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Gene3D G3DSA:3.40.50.720 184 309 5.7E-34 T 12-10-2018 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 Pfam PF13380 CoA binding domain 189 315 4.7E-18 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_35425 1a62763f20121b131d5216dcfc1a23d6 842 SMART SM00881 185 280 5.7E-22 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_23640 8e9c140a60e32339875ea1842d2d43c0 573 Gene3D G3DSA:3.40.50.300 337 573 3.8E-62 T 12-10-2018 AFR_23640 8e9c140a60e32339875ea1842d2d43c0 573 Pfam PF00005 ABC transporter 359 496 5.8E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_23640 8e9c140a60e32339875ea1842d2d43c0 573 Gene3D G3DSA:1.20.1560.10 8 331 1.5E-56 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_23640 8e9c140a60e32339875ea1842d2d43c0 573 SUPERFAMILY SSF90123 19 331 2.22E-57 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_23640 8e9c140a60e32339875ea1842d2d43c0 573 SUPERFAMILY SSF52540 338 565 6.61E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_23640 8e9c140a60e32339875ea1842d2d43c0 573 SMART SM00382 368 542 1.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_23640 8e9c140a60e32339875ea1842d2d43c0 573 Pfam PF00664 ABC transporter transmembrane region 31 298 1.1E-29 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_20785 a8c8aaef2d768a25f899045c32119d13 100 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 1 93 1.0E-37 T 12-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 AFR_20785 a8c8aaef2d768a25f899045c32119d13 100 Gene3D G3DSA:3.10.129.10 1 98 7.5E-38 T 12-10-2018 AFR_20785 a8c8aaef2d768a25f899045c32119d13 100 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 1 89 1.1E-17 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFR_20785 a8c8aaef2d768a25f899045c32119d13 100 SUPERFAMILY SSF54637 1 95 7.62E-24 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_20785 a8c8aaef2d768a25f899045c32119d13 100 Pfam PF03061 Thioesterase superfamily 11 84 4.0E-14 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00385 P450 superfamily signature 274 285 4.8E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00385 P450 superfamily signature 342 351 4.8E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00385 P450 superfamily signature 239 256 4.8E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00385 P450 superfamily signature 351 362 4.8E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 SUPERFAMILY SSF48264 20 402 1.18E-104 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 Gene3D G3DSA:1.10.630.10 5 402 2.7E-139 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 Pfam PF00067 Cytochrome P450 189 371 2.5E-26 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 321 336 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 342 351 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 293 320 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 90 101 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 351 362 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 192 214 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 274 285 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 137 153 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 PRINTS PR00359 B-class P450 signature 154 169 1.9E-64 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_28005 9026a1bd6a148bae3b68fda5c7252b2f 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 554 569 1.1E-6 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 83 99 1.1E-6 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 67 76 1.1E-6 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 49 59 1.1E-6 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 SUPERFAMILY SSF49785 418 590 1.28E-27 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 63 332 2.2E-54 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 SUPERFAMILY SSF53474 32 369 2.32E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 359 590 5.2E-29 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 63 251 9.4E-20 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 Gene3D G3DSA:3.40.50.1820 257 420 7.7E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 Gene3D G3DSA:3.40.50.1820 47 238 7.8E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_31765 b618990bc129ccb0aae08bc766343f0d 624 SMART SM00939 347 586 3.4E-32 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 SUPERFAMILY SSF51905 3 351 2.82E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 Gene3D G3DSA:3.50.50.60 4 326 4.8E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 Gene3D G3DSA:3.40.30.120 373 467 2.4E-27 T 12-10-2018 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 262 277 1.0E-43 T 12-10-2018 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 293 1.0E-43 T 12-10-2018 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.0E-43 T 12-10-2018 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 313 1.0E-43 T 12-10-2018 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 1.0E-43 T 12-10-2018 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.0E-43 T 12-10-2018 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 Pfam PF01494 FAD binding domain 4 328 8.3E-84 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_14665 98a6061f3b69c50a058dd37b6898bb8f 472 Gene3D G3DSA:3.30.70.2450 173 251 4.8E-117 T 12-10-2018 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 SMART SM00421 157 214 1.5E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 Pfam PF00072 Response regulator receiver domain 7 121 4.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 Gene3D G3DSA:3.40.50.12740 5 220 4.2E-66 T 12-10-2018 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 SUPERFAMILY SSF52172 3 131 1.08E-31 T 12-10-2018 IPR011006 CheY-like superfamily AFR_14810 d4a88a4867c049ce1360d132392da1db 227 SUPERFAMILY SSF46894 143 221 5.1E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 SMART SM00448 5 120 1.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_14810 d4a88a4867c049ce1360d132392da1db 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 214 5.1E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 SMART SM00387 411 515 3.6E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 SUPERFAMILY SSF55785 208 305 9.71E-6 T 12-10-2018 IPR035965 PAS domain superfamily AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 Gene3D G3DSA:3.30.450.20 194 307 3.7E-22 T 12-10-2018 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 Gene3D G3DSA:3.30.565.10 386 517 9.4E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 Gene3D G3DSA:3.30.450.20 32 165 2.2E-10 T 12-10-2018 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 319 361 5.6E-10 T 12-10-2018 IPR039506 SpoOB, alpha-helical domain AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 Pfam PF17203 Single cache domain 3 35 165 1.9E-15 T 12-10-2018 IPR033463 Single cache domain 3 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 SUPERFAMILY SSF103190 39 162 1.29E-11 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 SUPERFAMILY SSF55890 323 361 4.84E-10 T 12-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 Pfam PF00989 PAS fold 208 255 2.5E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 415 514 3.1E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 SMART SM00091 208 273 0.0092 T 12-10-2018 IPR000014 PAS domain AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 476 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 462 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_15875 52b7bd5f24b5e76672cc9a49bb13adfd 519 SUPERFAMILY SSF55874 386 513 7.2E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28190 6539172e3e7d810e0b70f9982eb9c686 423 Gene3D G3DSA:1.10.510.10 7 256 1.9E-30 T 12-10-2018 AFR_28190 6539172e3e7d810e0b70f9982eb9c686 423 SUPERFAMILY SSF56112 10 253 1.58E-36 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_28190 6539172e3e7d810e0b70f9982eb9c686 423 Pfam PF00069 Protein kinase domain 9 248 1.4E-19 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_28190 6539172e3e7d810e0b70f9982eb9c686 423 SMART SM00220 4 255 8.0E-12 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_25225 78fd63266ea1721de79095c6a9a93406 260 Gene3D G3DSA:2.60.120.620 3 229 1.0E-12 T 12-10-2018 AFR_25225 78fd63266ea1721de79095c6a9a93406 260 SUPERFAMILY SSF51197 2 234 1.83E-21 T 12-10-2018 AFR_25225 78fd63266ea1721de79095c6a9a93406 260 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 66 220 3.7E-6 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase AFR_15685 d614752f35cdaeec62e2e3dd6ea11bd1 571 SUPERFAMILY SSF161098 24 290 2.71E-46 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15685 d614752f35cdaeec62e2e3dd6ea11bd1 571 Gene3D G3DSA:1.10.3720.10 29 292 1.4E-45 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15685 d614752f35cdaeec62e2e3dd6ea11bd1 571 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 285 2.7E-9 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_15685 d614752f35cdaeec62e2e3dd6ea11bd1 571 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 385 559 8.4E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_15685 d614752f35cdaeec62e2e3dd6ea11bd1 571 Gene3D G3DSA:1.10.3720.10 313 569 1.9E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15685 d614752f35cdaeec62e2e3dd6ea11bd1 571 SUPERFAMILY SSF161098 313 564 2.83E-55 T 12-10-2018 IPR035906 MetI-like superfamily AFR_27170 403003731ca1c9600110ebddd84164ad 318 Gene3D G3DSA:1.10.10.10 1 83 1.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27170 403003731ca1c9600110ebddd84164ad 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_27170 403003731ca1c9600110ebddd84164ad 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_27170 403003731ca1c9600110ebddd84164ad 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_27170 403003731ca1c9600110ebddd84164ad 318 Pfam PF03466 LysR substrate binding domain 87 282 1.0E-24 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_27170 403003731ca1c9600110ebddd84164ad 318 SUPERFAMILY SSF53850 87 266 6.27E-26 T 12-10-2018 AFR_27170 403003731ca1c9600110ebddd84164ad 318 Gene3D G3DSA:3.40.190.10 92 282 9.9E-19 T 12-10-2018 AFR_27170 403003731ca1c9600110ebddd84164ad 318 SUPERFAMILY SSF46785 4 78 2.11E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27170 403003731ca1c9600110ebddd84164ad 318 Gene3D G3DSA:3.40.190.10 164 264 9.9E-19 T 12-10-2018 AFR_27170 403003731ca1c9600110ebddd84164ad 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.4E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_01205 ed9b4a5940edf0b57e4d9902d9a214f4 117 Gene3D G3DSA:3.30.750.24 1 113 6.7E-36 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01205 ed9b4a5940edf0b57e4d9902d9a214f4 117 Pfam PF01740 STAS domain 5 108 1.5E-19 T 12-10-2018 IPR002645 STAS domain AFR_01205 ed9b4a5940edf0b57e4d9902d9a214f4 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 107 8.0E-30 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_01205 ed9b4a5940edf0b57e4d9902d9a214f4 117 SUPERFAMILY SSF52091 3 109 2.35E-28 T 12-10-2018 IPR036513 STAS domain superfamily AFR_25345 7d87c6ea245fff44f4feee3e4e78ab55 289 SUPERFAMILY SSF46689 239 287 3.36E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_25345 7d87c6ea245fff44f4feee3e4e78ab55 289 Pfam PF12833 Helix-turn-helix domain 209 287 9.6E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_25345 7d87c6ea245fff44f4feee3e4e78ab55 289 Gene3D G3DSA:1.10.10.60 184 244 1.4E-14 T 12-10-2018 AFR_25345 7d87c6ea245fff44f4feee3e4e78ab55 289 Gene3D G3DSA:1.10.10.60 245 289 1.0E-10 T 12-10-2018 AFR_25345 7d87c6ea245fff44f4feee3e4e78ab55 289 SMART SM00342 203 286 7.7E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_25345 7d87c6ea245fff44f4feee3e4e78ab55 289 SUPERFAMILY SSF46689 187 237 2.24E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 SUPERFAMILY SSF47807 176 267 6.43E-14 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 SMART SM00279 179 214 5.8E-6 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 SUPERFAMILY SSF88723 7 158 9.42E-31 T 12-10-2018 IPR029060 PIN-like domain superfamily AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 Gene3D G3DSA:1.10.150.20 180 263 6.2E-58 T 12-10-2018 AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 Gene3D G3DSA:3.40.50.1010 8 269 6.2E-58 T 12-10-2018 AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 8 160 4.5E-33 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 178 272 2.4E-14 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 AFR_17675 a1c0f7743433f2c852836ab3660e09cc 340 SMART SM00475 5 277 4.3E-47 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFR_11145 deed929aa629bdd4b6dae59fe2f7f13c 180 Gene3D G3DSA:3.40.630.30 1 177 3.3E-43 T 12-10-2018 AFR_11145 deed929aa629bdd4b6dae59fe2f7f13c 180 SUPERFAMILY SSF55729 4 153 8.26E-38 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_11145 deed929aa629bdd4b6dae59fe2f7f13c 180 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 5.4E-30 T 12-10-2018 IPR000182 GNAT domain AFR_36120 fe53bb0614b35778893e1b36958ffc36 235 Gene3D G3DSA:3.40.50.300 1 201 4.4E-27 T 12-10-2018 AFR_36120 fe53bb0614b35778893e1b36958ffc36 235 Pfam PF00005 ABC transporter 20 140 9.2E-9 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_36120 fe53bb0614b35778893e1b36958ffc36 235 SMART SM00382 28 190 1.7E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36120 fe53bb0614b35778893e1b36958ffc36 235 SUPERFAMILY SSF52540 3 176 4.77E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 Gene3D G3DSA:3.20.20.80 79 407 1.1E-144 T 12-10-2018 AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 Gene3D G3DSA:2.80.10.50 477 567 1.7E-27 T 12-10-2018 AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 SUPERFAMILY SSF50370 480 603 7.18E-40 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 SMART SM00458 479 605 3.7E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 83 403 6.4E-37 T 12-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 Pfam PF00652 Ricin-type beta-trefoil lectin domain 481 602 4.8E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 406 466 1.4E-15 T 12-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 SUPERFAMILY SSF51445 81 407 9.7E-71 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 Gene3D G3DSA:2.60.40.1180 66 468 1.1E-144 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 Gene3D G3DSA:2.80.10.50 568 604 2.3E-12 T 12-10-2018 AFR_23400 0b3273c8f23bae8e147be31246f15e87 606 SUPERFAMILY SSF51011 402 468 1.17E-9 T 12-10-2018 AFR_23720 ed9efbf5287f0016f2f9cc3ca4f700d1 315 SUPERFAMILY SSF53850 89 293 9.72E-32 T 12-10-2018 AFR_23720 ed9efbf5287f0016f2f9cc3ca4f700d1 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.3E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23720 ed9efbf5287f0016f2f9cc3ca4f700d1 315 Gene3D G3DSA:1.10.10.10 2 87 1.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23720 ed9efbf5287f0016f2f9cc3ca4f700d1 315 Gene3D G3DSA:3.40.190.10 93 276 3.2E-37 T 12-10-2018 AFR_23720 ed9efbf5287f0016f2f9cc3ca4f700d1 315 Gene3D G3DSA:3.40.190.10 170 269 3.2E-37 T 12-10-2018 AFR_23720 ed9efbf5287f0016f2f9cc3ca4f700d1 315 Pfam PF03466 LysR substrate binding domain 89 292 4.6E-36 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_23720 ed9efbf5287f0016f2f9cc3ca4f700d1 315 SUPERFAMILY SSF46785 3 112 5.22E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19395 fe2f57bc7b55e79432e0cebd79c0c7f8 529 SUPERFAMILY SSF161098 279 515 2.22E-55 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19395 fe2f57bc7b55e79432e0cebd79c0c7f8 529 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 315 513 1.3E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_19395 fe2f57bc7b55e79432e0cebd79c0c7f8 529 Gene3D G3DSA:1.20.58.370 22 107 2.2E-7 T 12-10-2018 IPR035277 MalF, N-terminal AFR_19395 fe2f57bc7b55e79432e0cebd79c0c7f8 529 Gene3D G3DSA:1.10.3720.10 289 525 2.6E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19395 fe2f57bc7b55e79432e0cebd79c0c7f8 529 Pfam PF16296 N-terminal of TM subunit in PBP-dependent ABC transporters 85 167 9.9E-35 T 12-10-2018 IPR032550 PBP-dependent ABC transporters TM subunit, N-terminal AFR_19395 fe2f57bc7b55e79432e0cebd79c0c7f8 529 SUPERFAMILY SSF160964 26 278 3.53E-60 T 12-10-2018 AFR_35965 657027f4562b059fd6d7572e62a85ade 97 SUPERFAMILY SSF103007 5 93 2.48E-23 T 12-10-2018 IPR036746 TT1725-like superfamily AFR_35965 657027f4562b059fd6d7572e62a85ade 97 Gene3D G3DSA:3.30.70.1120 2 96 2.3E-17 T 12-10-2018 IPR036746 TT1725-like superfamily AFR_35965 657027f4562b059fd6d7572e62a85ade 97 Pfam PF04456 Protein of unknown function (DUF503) 14 89 4.4E-25 T 12-10-2018 IPR007546 Protein of unknown function DUF503 AFR_15710 3b14b2fb46076c62e9835e1b32ec0264 155 Pfam PF02627 Carboxymuconolactone decarboxylase family 55 136 3.7E-24 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_15710 3b14b2fb46076c62e9835e1b32ec0264 155 Gene3D G3DSA:1.20.1290.10 22 145 1.7E-38 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_15710 3b14b2fb46076c62e9835e1b32ec0264 155 SUPERFAMILY SSF69118 22 138 8.97E-36 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_04760 414b606ca57e3402c0b8829d1101cb89 1083 SUPERFAMILY SSF55874 547 665 2.62E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_04760 414b606ca57e3402c0b8829d1101cb89 1083 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 563 666 3.1E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_04760 414b606ca57e3402c0b8829d1101cb89 1083 Gene3D G3DSA:3.30.565.10 524 668 5.1E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_04760 414b606ca57e3402c0b8829d1101cb89 1083 Pfam PF00672 HAMP domain 368 442 6.7E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_04760 414b606ca57e3402c0b8829d1101cb89 1083 Pfam PF08376 Nitrate and nitrite sensing 98 329 3.1E-29 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein AFR_04760 414b606ca57e3402c0b8829d1101cb89 1083 SMART SM00387 558 668 3.3E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_25115 0b36f16b75152e2dbcd7bfe7b8835435 338 PIRSF PIRSF028757 35 336 6.8E-76 T 12-10-2018 IPR003507 Peptidase family S66 AFR_25115 0b36f16b75152e2dbcd7bfe7b8835435 338 SUPERFAMILY SSF141986 200 329 3.66E-37 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_25115 0b36f16b75152e2dbcd7bfe7b8835435 338 Gene3D G3DSA:3.50.30.60 186 332 1.4E-38 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_25115 0b36f16b75152e2dbcd7bfe7b8835435 338 Pfam PF02016 LD-carboxypeptidase 47 323 3.7E-74 T 12-10-2018 IPR003507 Peptidase family S66 AFR_25115 0b36f16b75152e2dbcd7bfe7b8835435 338 Gene3D G3DSA:3.40.50.10740 32 185 1.4E-45 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal AFR_25115 0b36f16b75152e2dbcd7bfe7b8835435 338 SUPERFAMILY SSF52317 36 192 5.49E-41 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_18535 a14fdf5fdf97881a568214a82bd18d02 88 Pfam PF00550 Phosphopantetheine attachment site 16 80 1.7E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_18535 a14fdf5fdf97881a568214a82bd18d02 88 SUPERFAMILY SSF47336 9 85 1.57E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_18535 a14fdf5fdf97881a568214a82bd18d02 88 SMART SM01294 15 81 6.5E-4 T 12-10-2018 AFR_18535 a14fdf5fdf97881a568214a82bd18d02 88 SMART SM00823 Phosphopantetheine attachment site 14 85 2.5E-14 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_18535 a14fdf5fdf97881a568214a82bd18d02 88 Gene3D G3DSA:1.10.1200.10 1 88 2.0E-35 T 12-10-2018 IPR036736 ACP-like superfamily AFR_20145 7fc83bd8a0c8460874e3946f5039690d 463 PIRSF PIRSF006446 1 460 2.9E-122 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFR_20145 7fc83bd8a0c8460874e3946f5039690d 463 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 444 6.5E-141 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFR_33985 ac0bbcfce8f2ccfa06277db9068067ff 205 Pfam PF02570 Precorrin-8X methylmutase 9 202 3.7E-73 T 12-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 AFR_33985 ac0bbcfce8f2ccfa06277db9068067ff 205 Gene3D G3DSA:3.40.50.10230 1 205 3.3E-81 T 12-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AFR_33985 ac0bbcfce8f2ccfa06277db9068067ff 205 SUPERFAMILY SSF63965 2 202 3.79E-72 T 12-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 SMART SM00924 179 282 3.9E-32 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 Pfam PF00571 CBS domain 359 403 7.5E-5 T 12-10-2018 IPR000644 CBS domain AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 Pfam PF00571 CBS domain 282 344 1.5E-5 T 12-10-2018 IPR000644 CBS domain AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 Pfam PF03448 MgtE intracellular N domain 179 279 1.2E-24 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 SUPERFAMILY SSF54631 281 414 3.42E-22 T 12-10-2018 AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 Gene3D G3DSA:3.10.580.10 279 406 1.1E-27 T 12-10-2018 AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 Gene3D G3DSA:1.25.60.10 150 277 8.9E-27 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 SUPERFAMILY SSF158791 163 278 3.66E-29 T 12-10-2018 AFR_40045 2bc3804bd29d192cb9211ecf11e48d40 429 SUPERFAMILY SSF50346 6 87 4.71E-6 T 12-10-2018 IPR011033 PRC-barrel-like superfamily AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 SMART SM00304 107 160 5.1E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 3.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 382 3.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 320 3.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 SUPERFAMILY SSF55874 218 384 6.29E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 SUPERFAMILY SSF158472 109 157 3.27E-7 T 12-10-2018 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 Pfam PF00512 His Kinase A (phospho-acceptor) domain 162 227 4.3E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 SMART SM00387 269 385 1.1E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 Pfam PF00672 HAMP domain 108 156 6.2E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 Gene3D G3DSA:1.10.287.130 111 229 2.8E-27 T 12-10-2018 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 Gene3D G3DSA:3.30.565.10 239 390 8.1E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 269 383 2.6E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 SMART SM00388 161 228 3.3E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_36770 3a67be2d2022057fe851f528d118b1b9 399 SUPERFAMILY SSF47384 144 229 4.32E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_34570 70a0cb839da87749b2c6cfc35890e9f3 197 Gene3D G3DSA:3.30.70.100 8 101 3.7E-5 T 12-10-2018 AFR_34570 70a0cb839da87749b2c6cfc35890e9f3 197 Pfam PF03992 Antibiotic biosynthesis monooxygenase 11 80 2.7E-6 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_34570 70a0cb839da87749b2c6cfc35890e9f3 197 SUPERFAMILY SSF54909 7 109 8.23E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_35495 9f1f73c4d438308d7e8b94874a058700 554 Gene3D G3DSA:3.40.50.1110 226 554 1.1E-54 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_35495 9f1f73c4d438308d7e8b94874a058700 554 SUPERFAMILY SSF52266 230 554 6.77E-37 T 12-10-2018 AFR_35495 9f1f73c4d438308d7e8b94874a058700 554 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 232 542 2.4E-8 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 152 3.4E-45 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 149 4.1E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 Pfam PF08281 Sigma-70, region 4 94 146 3.4E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 Gene3D G3DSA:1.10.1740.10 1 74 1.8E-10 T 12-10-2018 AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 Pfam PF04542 Sigma-70 region 2 9 72 1.4E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 SUPERFAMILY SSF88659 90 151 9.72E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 Gene3D G3DSA:1.10.10.10 78 153 4.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31155 360300d0b2f701ce00c55d704766b7b9 161 SUPERFAMILY SSF88946 3 83 2.43E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_19430 6a88b1eefcba27c724dc8950e73780ba 138 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 134 1.3E-21 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_19430 6a88b1eefcba27c724dc8950e73780ba 138 Gene3D G3DSA:2.30.110.10 1 136 3.5E-41 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_19430 6a88b1eefcba27c724dc8950e73780ba 138 Pfam PF04075 F420H(2)-dependent quinone reductase 10 132 1.6E-29 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_08460 4608e4b0aff48a14468752e5d861cd73 273 Pfam PF00588 SpoU rRNA Methylase family 119 264 3.0E-35 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFR_08460 4608e4b0aff48a14468752e5d861cd73 273 Gene3D G3DSA:3.30.1330.30 10 108 4.1E-23 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFR_08460 4608e4b0aff48a14468752e5d861cd73 273 Gene3D G3DSA:3.40.1280.10 110 273 1.5E-59 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFR_08460 4608e4b0aff48a14468752e5d861cd73 273 SUPERFAMILY SSF75217 119 270 3.2E-41 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFR_08460 4608e4b0aff48a14468752e5d861cd73 273 SUPERFAMILY SSF55315 8 105 2.59E-9 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFR_09345 4dbbd9e909910afc4ff73afc52699a9f 451 Gene3D G3DSA:3.65.10.10 8 447 2.2E-131 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_09345 4dbbd9e909910afc4ff73afc52699a9f 451 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 5 450 1.1E-125 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_09345 4dbbd9e909910afc4ff73afc52699a9f 451 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 3 451 34.767 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_09345 4dbbd9e909910afc4ff73afc52699a9f 451 Gene3D G3DSA:3.65.10.10 23 236 2.2E-131 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_09345 4dbbd9e909910afc4ff73afc52699a9f 451 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 441 3.8E-55 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFR_09345 4dbbd9e909910afc4ff73afc52699a9f 451 SUPERFAMILY SSF55205 5 450 2.29E-108 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 Gene3D G3DSA:2.60.40.290 25 133 3.8E-33 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 SUPERFAMILY SSF49384 28 132 1.19E-28 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 SMART SM00637 32 131 9.2E-41 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 Pfam PF01341 Glycosyl hydrolases family 6 191 529 9.2E-90 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PIRSF PIRSF001100 5 580 5.2E-114 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 246 262 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 SUPERFAMILY SSF51989 171 580 1.44E-101 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 Pfam PF00553 Cellulose binding domain 32 131 6.7E-27 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PRINTS PR00733 Glycosyl hydrolase family 6 signature 189 208 4.8E-35 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PRINTS PR00733 Glycosyl hydrolase family 6 signature 483 503 4.8E-35 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PRINTS PR00733 Glycosyl hydrolase family 6 signature 340 353 4.8E-35 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PRINTS PR00733 Glycosyl hydrolase family 6 signature 506 520 4.8E-35 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PRINTS PR00733 Glycosyl hydrolase family 6 signature 379 389 4.8E-35 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PRINTS PR00733 Glycosyl hydrolase family 6 signature 241 254 4.8E-35 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 PRINTS PR00733 Glycosyl hydrolase family 6 signature 442 455 4.8E-35 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_27300 8a928a8986fdc23a09f96726c8f7fec7 581 Gene3D G3DSA:3.20.20.40 169 580 4.0E-164 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 SUPERFAMILY SSF52949 32 125 5.53E-6 T 12-10-2018 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 156 463 6.5E-111 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 PRINTS PR00481 Cytosol aminopeptidase signature 291 312 2.9E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 PRINTS PR00481 Cytosol aminopeptidase signature 342 357 2.9E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 PRINTS PR00481 Cytosol aminopeptidase signature 254 275 2.9E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 PRINTS PR00481 Cytosol aminopeptidase signature 232 249 2.9E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 PRINTS PR00481 Cytosol aminopeptidase signature 313 333 2.9E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 Gene3D G3DSA:3.40.630.10 138 470 1.3E-120 T 12-10-2018 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 Gene3D G3DSA:3.40.220.10 24 134 2.4E-8 T 12-10-2018 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 35 120 5.1E-6 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 317 324 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFR_40075 9e80d11d203c03b189f4c5bd829a5240 470 SUPERFAMILY SSF53187 151 468 6.28E-103 T 12-10-2018 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 Gene3D G3DSA:1.25.40.10 90 240 2.1E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 Gene3D G3DSA:3.40.50.300 241 384 1.0E-11 T 12-10-2018 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 Gene3D G3DSA:1.25.40.10 658 863 5.2E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 SUPERFAMILY SSF52540 245 509 7.62E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 SUPERFAMILY SSF46894 3 86 1.02E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 SMART SM00862 16 86 2.6E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 SUPERFAMILY SSF48452 89 242 6.2E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 Gene3D G3DSA:1.10.10.10 1 89 8.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 PRINTS PR00364 Disease resistance protein signature 267 282 2.1E-5 T 12-10-2018 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 PRINTS PR00364 Disease resistance protein signature 445 459 2.1E-5 T 12-10-2018 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 PRINTS PR00364 Disease resistance protein signature 339 353 2.1E-5 T 12-10-2018 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 SMART SM01043 93 228 1.5E-33 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 Pfam PF03704 Bacterial transcriptional activator domain 94 228 1.9E-26 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 Pfam PF00486 Transcriptional regulatory protein, C terminal 17 76 2.8E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_05910 d50d7f4075de911b4162b78795ef07f3 930 SUPERFAMILY SSF48452 683 822 1.52E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06425 88febdc085171fd35599118cbbdfa485 548 Gene3D G3DSA:3.40.50.10730 138 344 3.4E-241 T 12-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 TIGRFAM TIGR01228 hutU: urocanate hydratase 7 537 1.4E-269 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 Pfam PF17392 Urocanase C-terminal domain 347 538 4.7E-91 T 12-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 Hamap MF_00577 Urocanate hydratase [hutU]. 3 547 48.771 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 Gene3D G3DSA:3.40.1770.10 17 536 3.4E-241 T 12-10-2018 AFR_06425 88febdc085171fd35599118cbbdfa485 548 SUPERFAMILY SSF111326 4 538 2.22E-241 T 12-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 Pfam PF17391 Urocanase N-terminal domain 8 134 2.0E-57 T 12-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 ProSitePatterns PS01233 Urocanase signature. 437 452 - T 12-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 PIRSF PIRSF001423 1 546 8.3E-270 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06425 88febdc085171fd35599118cbbdfa485 548 Pfam PF01175 Urocanase Rossmann-like domain 137 344 1.8E-82 T 12-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_35350 650954bdab67b5a0c61ee07e3b4f6a18 315 Gene3D G3DSA:3.40.1790.10 3 304 6.8E-110 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 AFR_35350 650954bdab67b5a0c61ee07e3b4f6a18 315 SUPERFAMILY SSF110581 6 302 1.31E-97 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 AFR_35350 650954bdab67b5a0c61ee07e3b4f6a18 315 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 10 304 39.45 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 AFR_35350 650954bdab67b5a0c61ee07e3b4f6a18 315 Pfam PF04227 Indigoidine synthase A like protein 12 300 1.9E-111 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 AFR_17210 855a6891abd98a5f6a0c41254e79d97c 75 SUPERFAMILY SSF47413 1 69 3.44E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_17210 855a6891abd98a5f6a0c41254e79d97c 75 SMART SM00530 6 62 2.2E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_17210 855a6891abd98a5f6a0c41254e79d97c 75 Gene3D G3DSA:1.10.260.40 5 68 1.6E-8 T 12-10-2018 AFR_17210 855a6891abd98a5f6a0c41254e79d97c 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 2.0E-19 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_04125 37f97bdf45e174670c0afe10a7e026a0 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.6E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_04125 37f97bdf45e174670c0afe10a7e026a0 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 72 87 1.6E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_04125 37f97bdf45e174670c0afe10a7e026a0 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 129 142 1.6E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_04125 37f97bdf45e174670c0afe10a7e026a0 319 Pfam PF12697 Alpha/beta hydrolase family 50 305 6.7E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_04125 37f97bdf45e174670c0afe10a7e026a0 319 SUPERFAMILY SSF53474 19 312 5.04E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_04125 37f97bdf45e174670c0afe10a7e026a0 319 Gene3D G3DSA:3.40.50.1820 18 313 2.2E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_37685 b40f5a2cc2a1189003b0b5cb8e99e28d 118 Gene3D G3DSA:3.30.750.24 4 107 3.0E-21 T 12-10-2018 IPR036513 STAS domain superfamily AFR_37685 b40f5a2cc2a1189003b0b5cb8e99e28d 118 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 11 101 1.3E-16 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_37685 b40f5a2cc2a1189003b0b5cb8e99e28d 118 SUPERFAMILY SSF52091 9 103 2.94E-17 T 12-10-2018 IPR036513 STAS domain superfamily AFR_37685 b40f5a2cc2a1189003b0b5cb8e99e28d 118 Pfam PF13466 STAS domain 20 97 1.5E-11 T 12-10-2018 IPR002645 STAS domain AFR_26405 ff6c35f15d143dc5f98c9d3f5d29f743 279 Pfam PF00227 Proteasome subunit 52 234 9.1E-35 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFR_26405 ff6c35f15d143dc5f98c9d3f5d29f743 279 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 273 6.9E-109 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 AFR_26405 ff6c35f15d143dc5f98c9d3f5d29f743 279 SUPERFAMILY SSF56235 47 267 9.16E-55 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_26405 ff6c35f15d143dc5f98c9d3f5d29f743 279 Gene3D G3DSA:3.60.20.10 54 279 4.4E-84 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_26405 ff6c35f15d143dc5f98c9d3f5d29f743 279 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 279 49.027 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 AFR_41300 c5333243ebea09b560742fbe042416f7 385 SUPERFAMILY SSF47203 229 373 1.21E-21 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_41300 c5333243ebea09b560742fbe042416f7 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 211 1.0E-16 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_41300 c5333243ebea09b560742fbe042416f7 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 84 2.6E-12 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_41300 c5333243ebea09b560742fbe042416f7 385 Gene3D G3DSA:2.40.110.10 121 225 8.3E-23 T 12-10-2018 AFR_41300 c5333243ebea09b560742fbe042416f7 385 Gene3D G3DSA:1.10.540.10 1 119 3.7E-28 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_41300 c5333243ebea09b560742fbe042416f7 385 SUPERFAMILY SSF56645 6 223 6.81E-47 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_41300 c5333243ebea09b560742fbe042416f7 385 Gene3D G3DSA:1.20.140.10 227 379 2.0E-27 T 12-10-2018 AFR_41300 c5333243ebea09b560742fbe042416f7 385 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 353 3.3E-15 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFR_41300 c5333243ebea09b560742fbe042416f7 385 PIRSF PIRSF016578 1 97 7.1E-11 T 12-10-2018 AFR_41300 c5333243ebea09b560742fbe042416f7 385 PIRSF PIRSF016578 127 381 2.6E-32 T 12-10-2018 AFR_08830 23de88906bbd9ec408e51f5d4e442fc8 269 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 5 238 1.2E-42 T 12-10-2018 IPR013402 Conserved hypothetical protein CHP02569 AFR_08830 23de88906bbd9ec408e51f5d4e442fc8 269 SUPERFAMILY SSF56112 15 241 1.5E-12 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_08830 23de88906bbd9ec408e51f5d4e442fc8 269 Gene3D G3DSA:3.90.1200.10 78 189 4.7E-6 T 12-10-2018 AFR_32415 8e66ce07963f3c511075f32871239415 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 2.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32415 8e66ce07963f3c511075f32871239415 220 SUPERFAMILY SSF46689 8 79 4.99E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_32415 8e66ce07963f3c511075f32871239415 220 Gene3D G3DSA:1.10.357.10 10 219 2.7E-53 T 12-10-2018 AFR_08720 884824fd065a369bbcfe603c8dd9e817 152 Gene3D G3DSA:1.20.140.160 6 135 4.8E-10 T 12-10-2018 AFR_08720 884824fd065a369bbcfe603c8dd9e817 152 SUPERFAMILY SSF88659 85 143 9.53E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_26620 0245ddfba62fc01f104474da3180d706 167 SUPERFAMILY SSF46785 30 161 1.89E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26620 0245ddfba62fc01f104474da3180d706 167 SMART SM00347 46 146 3.7E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_26620 0245ddfba62fc01f104474da3180d706 167 Pfam PF01047 MarR family 56 110 6.9E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_26620 0245ddfba62fc01f104474da3180d706 167 Gene3D G3DSA:1.10.10.10 27 163 1.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26620 0245ddfba62fc01f104474da3180d706 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 4.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_26620 0245ddfba62fc01f104474da3180d706 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 4.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 Gene3D G3DSA:1.10.357.10 40 172 2.5E-27 T 12-10-2018 AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 7.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 7.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 Pfam PF16859 Bacterial transcriptional repressor C-terminal 68 167 5.1E-23 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 SUPERFAMILY SSF48498 65 172 8.35E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 Gene3D G3DSA:1.10.10.60 1 39 1.5E-20 T 12-10-2018 AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 SUPERFAMILY SSF46689 2 58 2.29E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13010 8022e3d1b17a4446b211c66bbdf1603d 173 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 45 1.3E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02675 464611fff834aa1014018c8de8fb4e3a 469 SUPERFAMILY SSF53335 71 184 4.46E-8 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_02675 464611fff834aa1014018c8de8fb4e3a 469 Gene3D G3DSA:3.40.50.150 44 184 4.3E-7 T 12-10-2018 AFR_20540 20639fefad10b44af2a3b040359bfa85 314 Gene3D G3DSA:3.40.50.2300 56 291 1.8E-24 T 12-10-2018 AFR_20540 20639fefad10b44af2a3b040359bfa85 314 SMART SM00354 1 72 7.9E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_20540 20639fefad10b44af2a3b040359bfa85 314 SUPERFAMILY SSF47413 1 60 6.75E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_20540 20639fefad10b44af2a3b040359bfa85 314 Gene3D G3DSA:1.10.260.40 1 55 9.5E-21 T 12-10-2018 AFR_20540 20639fefad10b44af2a3b040359bfa85 314 SUPERFAMILY SSF53822 82 313 1.65E-24 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_20540 20639fefad10b44af2a3b040359bfa85 314 Pfam PF13377 Periplasmic binding protein-like domain 161 313 2.9E-25 T 12-10-2018 AFR_20540 20639fefad10b44af2a3b040359bfa85 314 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 6.3E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_20540 20639fefad10b44af2a3b040359bfa85 314 Gene3D G3DSA:3.40.50.2300 152 274 1.8E-24 T 12-10-2018 AFR_37385 f9fb3c96a412ee9d05a837109825d6b7 504 SUPERFAMILY SSF51735 1 290 2.78E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37385 f9fb3c96a412ee9d05a837109825d6b7 504 Gene3D G3DSA:3.40.50.720 4 281 2.5E-48 T 12-10-2018 AFR_37385 f9fb3c96a412ee9d05a837109825d6b7 504 SUPERFAMILY SSF55961 336 476 7.64E-8 T 12-10-2018 AFR_37385 f9fb3c96a412ee9d05a837109825d6b7 504 Pfam PF13460 NAD(P)H-binding 7 111 4.1E-21 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_37385 f9fb3c96a412ee9d05a837109825d6b7 504 Pfam PF11066 Protein of unknown function (DUF2867) 327 472 4.8E-39 T 12-10-2018 IPR021295 Protein of unknown function DUF2867 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 120 133 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 148 163 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 265 278 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 309 323 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 285 305 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 235 245 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 205 218 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PRINTS PR00733 Glycosyl hydrolase family 6 signature 78 97 7.1E-38 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 Gene3D G3DSA:3.20.20.40 57 346 2.5E-100 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 SUPERFAMILY SSF51989 48 344 6.41E-87 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 Pfam PF01341 Glycosyl hydrolases family 6 65 332 8.4E-80 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 165 174 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 AFR_05270 ee9747e54a512d2dc848b50002800bad 348 PIRSF PIRSF001100 13 346 3.5E-91 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 1.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 1.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 192 2.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 191 8.0E-20 T 12-10-2018 AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 Gene3D G3DSA:1.10.150.240 12 91 1.5E-40 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 SUPERFAMILY SSF56784 1 215 9.55E-44 T 12-10-2018 IPR036412 HAD-like superfamily AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 Gene3D G3DSA:3.40.50.1000 1 197 1.5E-40 T 12-10-2018 IPR023214 HAD superfamily AFR_32875 89fb1107ffddc6221e6cc704bf39905c 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 187 2.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 SUPERFAMILY SSF141868 12 203 4.97E-26 T 12-10-2018 IPR035919 EAL domain superfamily AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 Gene3D G3DSA:3.20.20.450 8 208 1.7E-16 T 12-10-2018 IPR035919 EAL domain superfamily AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 SUPERFAMILY SSF109604 192 392 4.71E-31 T 12-10-2018 AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 PIRSF PIRSF003180 8 405 9.6E-94 T 12-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 Pfam PF00563 EAL domain 87 199 2.7E-8 T 12-10-2018 IPR001633 EAL domain AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 Pfam PF08668 HDOD domain 215 328 1.0E-18 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 Gene3D G3DSA:1.10.3210.10 209 356 1.4E-23 T 12-10-2018 AFR_19670 d8977829cbe314dabb11b7b80e3e0cb2 407 SMART SM00052 2 204 3.9E-4 T 12-10-2018 IPR001633 EAL domain AFR_42035 863e3dcdfa7cd3fc0ccc774f0865b223 157 Pfam PF13671 AAA domain 6 142 3.9E-20 T 12-10-2018 AFR_42035 863e3dcdfa7cd3fc0ccc774f0865b223 157 SUPERFAMILY SSF52540 5 138 4.1E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42035 863e3dcdfa7cd3fc0ccc774f0865b223 157 Gene3D G3DSA:3.40.50.300 3 152 2.1E-26 T 12-10-2018 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 SMART SM00342 26 109 1.0E-31 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 SUPERFAMILY SSF46689 62 116 8.96E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 Pfam PF12833 Helix-turn-helix domain 32 110 6.5E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 SUPERFAMILY SSF46689 9 60 1.15E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 63 105 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 Gene3D G3DSA:1.10.10.60 5 113 4.3E-32 T 12-10-2018 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 78 93 2.0E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_01055 afec6a9152e35448a27e082947bc33d8 144 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 93 109 2.0E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_37840 a31d04eee82108bde3611383e4050e2b 372 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 13 290 1.3E-46 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_37840 a31d04eee82108bde3611383e4050e2b 372 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 12 293 8.1E-78 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_37840 a31d04eee82108bde3611383e4050e2b 372 SUPERFAMILY SSF55931 9 368 1.13E-87 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_37840 a31d04eee82108bde3611383e4050e2b 372 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 372 73.855 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_37840 a31d04eee82108bde3611383e4050e2b 372 Gene3D G3DSA:3.30.590.20 6 370 1.1E-112 T 12-10-2018 AFR_29770 068ab37aa45bc91345b3d5078eda312b 156 Pfam PF01047 MarR family 38 90 4.7E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29770 068ab37aa45bc91345b3d5078eda312b 156 Gene3D G3DSA:1.10.10.10 7 149 2.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29770 068ab37aa45bc91345b3d5078eda312b 156 SUPERFAMILY SSF46785 11 147 5.1E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29770 068ab37aa45bc91345b3d5078eda312b 156 SMART SM00347 31 131 1.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_41210 49f36f3796391629b7d8cbd3f6a909d5 374 Gene3D G3DSA:2.30.30.230 2 82 7.9E-18 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFR_41210 49f36f3796391629b7d8cbd3f6a909d5 374 Pfam PF09298 Fumarylacetoacetase N-terminal 8 91 3.0E-15 T 12-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFR_41210 49f36f3796391629b7d8cbd3f6a909d5 374 Gene3D G3DSA:3.90.850.10 90 374 6.4E-103 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_41210 49f36f3796391629b7d8cbd3f6a909d5 374 SUPERFAMILY SSF56529 94 372 1.96E-83 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_41210 49f36f3796391629b7d8cbd3f6a909d5 374 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 4 372 3.9E-116 T 12-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFR_41210 49f36f3796391629b7d8cbd3f6a909d5 374 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 98 372 2.2E-56 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFR_41210 49f36f3796391629b7d8cbd3f6a909d5 374 SUPERFAMILY SSF63433 4 92 1.83E-18 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFR_17230 2573ccc424d51e7101cb62beee20c003 409 SMART SM00065 20 166 6.8E-15 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_17230 2573ccc424d51e7101cb62beee20c003 409 Gene3D G3DSA:3.60.40.10 168 408 1.2E-40 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_17230 2573ccc424d51e7101cb62beee20c003 409 SUPERFAMILY SSF55781 22 159 2.4E-26 T 12-10-2018 AFR_17230 2573ccc424d51e7101cb62beee20c003 409 SUPERFAMILY SSF81606 204 407 7.32E-6 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_17230 2573ccc424d51e7101cb62beee20c003 409 Gene3D G3DSA:3.30.450.40 13 167 4.1E-23 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_17230 2573ccc424d51e7101cb62beee20c003 409 SMART SM00331 198 408 1.7E-18 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_17230 2573ccc424d51e7101cb62beee20c003 409 Pfam PF01590 GAF domain 22 154 6.0E-13 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_17230 2573ccc424d51e7101cb62beee20c003 409 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 226 408 4.2E-28 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_06175 870d85dc8094089f4e265599ec9d2434 237 Gene3D G3DSA:1.10.10.10 7 85 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06175 870d85dc8094089f4e265599ec9d2434 237 SMART SM00345 26 84 1.3E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_06175 870d85dc8094089f4e265599ec9d2434 237 Pfam PF07729 FCD domain 94 215 7.0E-16 T 12-10-2018 IPR011711 GntR, C-terminal AFR_06175 870d85dc8094089f4e265599ec9d2434 237 SUPERFAMILY SSF46785 23 108 3.31E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06175 870d85dc8094089f4e265599ec9d2434 237 SMART SM00895 94 218 5.8E-11 T 12-10-2018 IPR011711 GntR, C-terminal AFR_06175 870d85dc8094089f4e265599ec9d2434 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 84 8.5E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_06175 870d85dc8094089f4e265599ec9d2434 237 Gene3D G3DSA:1.20.120.530 87 229 8.8E-18 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_06175 870d85dc8094089f4e265599ec9d2434 237 SUPERFAMILY SSF48008 91 222 2.88E-19 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_35065 feeb5822560be796d83eb9c185f5cbbf 160 Gene3D G3DSA:1.10.287.70 19 148 2.1E-21 T 12-10-2018 AFR_35065 feeb5822560be796d83eb9c185f5cbbf 160 SUPERFAMILY SSF81324 31 111 3.92E-22 T 12-10-2018 AFR_35065 feeb5822560be796d83eb9c185f5cbbf 160 Pfam PF07885 Ion channel 39 103 2.8E-15 T 12-10-2018 IPR013099 Potassium channel domain AFR_31135 94a3e59416ae00b57af97164db1030d8 643 SUPERFAMILY SSF141868 392 637 3.14E-58 T 12-10-2018 IPR035919 EAL domain superfamily AFR_31135 94a3e59416ae00b57af97164db1030d8 643 SUPERFAMILY SSF55073 220 370 1.23E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_31135 94a3e59416ae00b57af97164db1030d8 643 Gene3D G3DSA:3.20.20.450 388 642 3.0E-65 T 12-10-2018 IPR035919 EAL domain superfamily AFR_31135 94a3e59416ae00b57af97164db1030d8 643 Gene3D G3DSA:3.30.70.270 200 372 2.8E-51 T 12-10-2018 AFR_31135 94a3e59416ae00b57af97164db1030d8 643 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 213 368 1.0E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_31135 94a3e59416ae00b57af97164db1030d8 643 SMART SM00052 385 629 7.4E-55 T 12-10-2018 IPR001633 EAL domain AFR_31135 94a3e59416ae00b57af97164db1030d8 643 Pfam PF00563 EAL domain 391 624 1.3E-50 T 12-10-2018 IPR001633 EAL domain AFR_31135 94a3e59416ae00b57af97164db1030d8 643 Pfam PF00990 Diguanylate cyclase, GGDEF domain 215 368 4.0E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_31135 94a3e59416ae00b57af97164db1030d8 643 SMART SM00267 204 373 8.1E-50 T 12-10-2018 IPR000160 GGDEF domain AFR_26390 bb7f1c1ff2747294f77faded363fe967 452 PIRSF PIRSF018077 1 452 1.2E-182 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 AFR_26390 bb7f1c1ff2747294f77faded363fe967 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 2.9E-230 T 12-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 AFR_26390 bb7f1c1ff2747294f77faded363fe967 452 Pfam PF03136 Pup-ligase protein 4 422 4.1E-158 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 AFR_26390 bb7f1c1ff2747294f77faded363fe967 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.719 T 12-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 SMART SM00267 346 513 6.8E-53 T 12-10-2018 IPR000160 GGDEF domain AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 Gene3D G3DSA:3.20.20.450 527 778 5.5E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 353 512 2.6E-35 T 12-10-2018 IPR000160 GGDEF domain AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 Gene3D G3DSA:3.30.70.270 351 526 2.7E-52 T 12-10-2018 AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 Pfam PF00563 EAL domain 529 765 1.8E-64 T 12-10-2018 IPR001633 EAL domain AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 SUPERFAMILY SSF141868 530 777 1.11E-80 T 12-10-2018 IPR035919 EAL domain superfamily AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 SUPERFAMILY SSF55073 362 515 2.04E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 Pfam PF00990 Diguanylate cyclase, GGDEF domain 357 508 6.2E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_11910 d8b05f4f361fd8e6ec0c64b2d6824533 786 SMART SM00052 523 770 5.9E-106 T 12-10-2018 IPR001633 EAL domain AFR_23410 48766125dd4ea4d499c02deba31c423b 267 Gene3D G3DSA:3.20.20.60 3 266 3.0E-45 T 12-10-2018 AFR_23410 48766125dd4ea4d499c02deba31c423b 267 SUPERFAMILY SSF51621 6 243 3.27E-34 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_23410 48766125dd4ea4d499c02deba31c423b 267 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 233 4.2E-24 T 12-10-2018 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 PRINTS PR00086 L-lactate dehydrogenase signature 123 143 9.6E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 PRINTS PR00086 L-lactate dehydrogenase signature 177 190 9.6E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 PRINTS PR00086 L-lactate dehydrogenase signature 147 165 9.6E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 PRINTS PR00086 L-lactate dehydrogenase signature 4 28 9.6E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 PRINTS PR00086 L-lactate dehydrogenase signature 29 53 9.6E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 3 309 2.7E-109 T 12-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 4 149 1.1E-36 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 Gene3D G3DSA:3.90.110.10 152 315 3.6E-51 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 SUPERFAMILY SSF51735 4 149 2.59E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 PIRSF PIRSF000102 1 316 6.9E-95 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 154 313 5.4E-19 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 Gene3D G3DSA:3.40.50.720 1 151 4.9E-49 T 12-10-2018 AFR_05125 3daed8b9ae1dcd64a31027709e3a5c8d 316 SUPERFAMILY SSF56327 151 309 5.04E-45 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFR_11090 36cc94bd5051423dd03cd89734832574 163 SUPERFAMILY SSF55811 6 141 9.34E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_11090 36cc94bd5051423dd03cd89734832574 163 PRINTS PR00502 NUDIX hydrolase family signature 64 78 3.8E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_11090 36cc94bd5051423dd03cd89734832574 163 PRINTS PR00502 NUDIX hydrolase family signature 78 93 3.8E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_11090 36cc94bd5051423dd03cd89734832574 163 Gene3D G3DSA:3.90.79.10 37 157 5.2E-17 T 12-10-2018 AFR_11090 36cc94bd5051423dd03cd89734832574 163 ProSitePatterns PS00893 Nudix box signature. 69 90 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_11090 36cc94bd5051423dd03cd89734832574 163 Pfam PF00293 NUDIX domain 39 103 2.5E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_22685 a4c7c5a78857389c1a28b073f4fb4b7e 556 Pfam PF06259 Alpha/beta hydrolase 326 492 2.1E-31 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 AFR_22685 a4c7c5a78857389c1a28b073f4fb4b7e 556 SUPERFAMILY SSF53474 337 490 2.05E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_08030 a9e9b0099aa9d60707c971f08c779ebe 571 SMART SM00481 92 167 1.1E-4 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFR_08030 a9e9b0099aa9d60707c971f08c779ebe 571 Gene3D G3DSA:3.20.20.140 82 409 2.4E-18 T 12-10-2018 AFR_08030 a9e9b0099aa9d60707c971f08c779ebe 571 SUPERFAMILY SSF89550 88 409 4.9E-16 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_29440 c8412a66e0ab53d719e8175975fedee0 206 SUPERFAMILY SSF48498 93 200 7.79E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_29440 c8412a66e0ab53d719e8175975fedee0 206 SUPERFAMILY SSF46689 11 81 3.89E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29440 c8412a66e0ab53d719e8175975fedee0 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 4.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29440 c8412a66e0ab53d719e8175975fedee0 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 4.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29440 c8412a66e0ab53d719e8175975fedee0 206 Gene3D G3DSA:1.10.357.10 22 205 7.6E-39 T 12-10-2018 AFR_29440 c8412a66e0ab53d719e8175975fedee0 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 70 1.4E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29440 c8412a66e0ab53d719e8175975fedee0 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 69 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_08575 81ab1b7259479ade89b43140b92ac80e 502 SUPERFAMILY SSF56112 9 278 3.91E-71 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_08575 81ab1b7259479ade89b43140b92ac80e 502 Gene3D G3DSA:1.10.510.10 98 276 1.8E-46 T 12-10-2018 AFR_08575 81ab1b7259479ade89b43140b92ac80e 502 Gene3D G3DSA:3.30.200.20 2 96 9.5E-29 T 12-10-2018 AFR_08575 81ab1b7259479ade89b43140b92ac80e 502 Pfam PF00069 Protein kinase domain 12 262 1.4E-40 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_08575 81ab1b7259479ade89b43140b92ac80e 502 SMART SM00220 12 272 1.0E-50 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_07950 a61f5d70c3a80347c074649b64969166 457 Pfam PF00144 Beta-lactamase 8 319 4.5E-52 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_07950 a61f5d70c3a80347c074649b64969166 457 SUPERFAMILY SSF56601 5 302 5.93E-64 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_07950 a61f5d70c3a80347c074649b64969166 457 Gene3D G3DSA:3.40.710.10 2 335 1.6E-64 T 12-10-2018 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 333 4.0E-109 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 154 302 4.4E-17 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 SUPERFAMILY SSF55347 145 301 8.72E-44 T 12-10-2018 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 SUPERFAMILY SSF51735 1 164 3.4E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 SMART SM00859 4 135 1.0E-43 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 133 2.0E-28 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 Gene3D G3DSA:3.40.50.720 5 319 6.1E-110 T 12-10-2018 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 327 38.881 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_30245 cf3b4c0051300aa49302b301a56c0ccf 333 Gene3D G3DSA:3.30.360.10 149 306 6.1E-110 T 12-10-2018 AFR_22310 f1aa614834039bf29ce4112ecfee39ae 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 262 1.3E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_22310 f1aa614834039bf29ce4112ecfee39ae 272 Gene3D G3DSA:1.10.3720.10 70 262 2.6E-26 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22310 f1aa614834039bf29ce4112ecfee39ae 272 SUPERFAMILY SSF161098 69 255 1.96E-31 T 12-10-2018 IPR035906 MetI-like superfamily AFR_38230 641c037bbdf42a2e8a522fb60868bd43 317 SUPERFAMILY SSF55874 204 304 1.37E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38230 641c037bbdf42a2e8a522fb60868bd43 317 Gene3D G3DSA:3.30.565.10 195 316 8.0E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38230 641c037bbdf42a2e8a522fb60868bd43 317 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 15 156 1.7E-23 T 12-10-2018 IPR025847 MEDS domain AFR_38230 641c037bbdf42a2e8a522fb60868bd43 317 Pfam PF13581 Histidine kinase-like ATPase domain 204 304 3.0E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00096 Glutamine amidotransferase superfamily signature 455 464 2.2E-11 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00096 Glutamine amidotransferase superfamily signature 566 579 2.2E-11 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00096 Glutamine amidotransferase superfamily signature 487 498 2.2E-11 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00097 Anthranilate synthase component II signature 415 429 6.2E-11 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00097 Anthranilate synthase component II signature 566 579 6.2E-11 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00097 Anthranilate synthase component II signature 487 498 6.2E-11 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 452 466 3.8E-7 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 487 503 3.8E-7 T 12-10-2018 AFR_11460 8738967ffec02b6053c403263e9642eb 601 Pfam PF00425 chorismate binding enzyme 102 356 1.7E-40 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFR_11460 8738967ffec02b6053c403263e9642eb 601 Pfam PF00117 Glutamine amidotransferase class-I 417 584 4.6E-22 T 12-10-2018 IPR017926 Glutamine amidotransferase AFR_11460 8738967ffec02b6053c403263e9642eb 601 Gene3D G3DSA:3.60.120.10 1 366 5.6E-117 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFR_11460 8738967ffec02b6053c403263e9642eb 601 SUPERFAMILY SSF52317 413 585 5.62E-28 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_11460 8738967ffec02b6053c403263e9642eb 601 SUPERFAMILY SSF56322 56 365 3.27E-58 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFR_11460 8738967ffec02b6053c403263e9642eb 601 Gene3D G3DSA:3.40.50.880 414 596 1.9E-41 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_15100 82042d62b358384fb98faf7442f88f4a 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 252 6.1E-52 T 12-10-2018 AFR_15100 82042d62b358384fb98faf7442f88f4a 256 SUPERFAMILY SSF51735 3 253 1.76E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15100 82042d62b358384fb98faf7442f88f4a 256 Gene3D G3DSA:3.40.50.720 2 254 4.6E-69 T 12-10-2018 AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.2E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.2E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.2E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.2E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15100 82042d62b358384fb98faf7442f88f4a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.2E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27485 b239897d96640dbcc3fba758f81b0ef5 169 SUPERFAMILY SSF46689 2 70 9.48E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_27485 b239897d96640dbcc3fba758f81b0ef5 169 Gene3D G3DSA:1.10.357.10 1 169 2.7E-43 T 12-10-2018 AFR_27485 b239897d96640dbcc3fba758f81b0ef5 169 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 2.7E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27485 b239897d96640dbcc3fba758f81b0ef5 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 9.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27485 b239897d96640dbcc3fba758f81b0ef5 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27485 b239897d96640dbcc3fba758f81b0ef5 169 SUPERFAMILY SSF48498 76 169 1.56E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_10510 bffc2c1be7044c8968b5d3004274f97f 204 Pfam PF00857 Isochorismatase family 12 193 2.5E-45 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_10510 bffc2c1be7044c8968b5d3004274f97f 204 Gene3D G3DSA:3.40.50.850 6 204 1.5E-58 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_10510 bffc2c1be7044c8968b5d3004274f97f 204 SUPERFAMILY SSF52499 5 204 3.01E-51 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SMART SM00388 391 460 1.1E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 505 613 6.8E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Gene3D G3DSA:3.30.565.10 459 614 8.2E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Gene3D G3DSA:1.10.287.130 376 458 9.2E-24 T 12-10-2018 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SUPERFAMILY SSF47384 374 461 2.75E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Gene3D G3DSA:3.40.50.12740 626 745 1.8E-35 T 12-10-2018 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Gene3D G3DSA:3.40.50.12740 746 837 5.6E-22 T 12-10-2018 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SUPERFAMILY SSF55874 449 613 1.83E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Pfam PF00072 Response regulator receiver domain 749 830 2.1E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Pfam PF00072 Response regulator receiver domain 629 737 1.1E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SUPERFAMILY SSF52172 744 833 3.7E-19 T 12-10-2018 IPR011006 CheY-like superfamily AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SUPERFAMILY SSF55781 233 374 3.07E-10 T 12-10-2018 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 555 3.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 593 3.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 612 3.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 569 3.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SUPERFAMILY SSF52172 626 744 1.42E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Gene3D G3DSA:3.30.450.40 211 375 8.1E-8 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 Pfam PF00512 His Kinase A (phospho-acceptor) domain 391 460 8.0E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SMART SM00448 627 737 1.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SMART SM00448 747 846 7.2E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35925 d56c93cac4813f4057dbf93b146873a5 883 SMART SM00387 504 615 9.4E-40 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_15610 c685f2e1e2f3efe528c47e2e3c01000c 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 5.9E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15610 c685f2e1e2f3efe528c47e2e3c01000c 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_15610 c685f2e1e2f3efe528c47e2e3c01000c 206 SUPERFAMILY SSF46689 11 78 7.09E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15610 c685f2e1e2f3efe528c47e2e3c01000c 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15610 c685f2e1e2f3efe528c47e2e3c01000c 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15610 c685f2e1e2f3efe528c47e2e3c01000c 206 Gene3D G3DSA:1.10.10.60 17 57 1.6E-15 T 12-10-2018 AFR_15610 c685f2e1e2f3efe528c47e2e3c01000c 206 Gene3D G3DSA:1.10.357.10 59 198 1.7E-27 T 12-10-2018 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 Pfam PF00005 ABC transporter 308 441 9.6E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 SUPERFAMILY SSF52540 4 209 3.55E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 SUPERFAMILY SSF52540 281 500 1.98E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 Pfam PF16326 ABC transporter C-terminal domain 536 596 7.9E-8 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 Gene3D G3DSA:3.40.50.300 267 506 2.4E-55 T 12-10-2018 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 Gene3D G3DSA:3.40.50.300 2 240 5.3E-55 T 12-10-2018 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 Pfam PF00005 ABC transporter 21 160 3.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 SMART SM00382 30 212 1.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_39785 7e63bce97bea33a43214d99d586ed0e8 601 SMART SM00382 316 494 9.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_28305 58b0cbe3eafbf497c3d0e5e6763f5c82 450 Gene3D G3DSA:1.20.1250.20 187 390 8.6E-12 T 12-10-2018 AFR_28305 58b0cbe3eafbf497c3d0e5e6763f5c82 450 SUPERFAMILY SSF103473 3 371 6.02E-32 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_28305 58b0cbe3eafbf497c3d0e5e6763f5c82 450 Gene3D G3DSA:1.20.1250.20 2 183 6.6E-18 T 12-10-2018 AFR_28305 58b0cbe3eafbf497c3d0e5e6763f5c82 450 Pfam PF07690 Major Facilitator Superfamily 6 194 4.2E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_28305 58b0cbe3eafbf497c3d0e5e6763f5c82 450 Pfam PF07690 Major Facilitator Superfamily 199 375 1.8E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 Pfam PF08448 PAS fold 183 291 2.0E-5 T 12-10-2018 IPR013656 PAS fold-4 AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 SUPERFAMILY SSF55874 362 512 5.76E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 Pfam PF12282 Signal transduction histidine kinase 4 156 1.1E-52 T 12-10-2018 IPR022066 Signal transduction histidine kinase, N-terminal AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 Pfam PF07568 Histidine kinase 305 375 1.8E-23 T 12-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 403 513 1.9E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 SMART SM00387 399 514 7.9E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 Gene3D G3DSA:3.30.450.280 1 141 5.8E-36 T 12-10-2018 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 Gene3D G3DSA:3.30.565.10 361 515 3.5E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38095 bcf7b54a08601a8e2bfc275053c1a677 515 Gene3D G3DSA:3.30.450.20 142 291 5.4E-42 T 12-10-2018 AFR_01115 d0ed9c19b03541793fd33c27de18160c 354 Pfam PF01471 Putative peptidoglycan binding domain 119 158 1.3E-4 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_01115 d0ed9c19b03541793fd33c27de18160c 354 Gene3D G3DSA:2.40.420.20 292 352 4.2E-9 T 12-10-2018 AFR_01115 d0ed9c19b03541793fd33c27de18160c 354 Gene3D G3DSA:2.40.50.100 65 204 4.2E-9 T 12-10-2018 AFR_01115 d0ed9c19b03541793fd33c27de18160c 354 Gene3D G3DSA:1.10.287.470 97 160 4.2E-9 T 12-10-2018 AFR_01115 d0ed9c19b03541793fd33c27de18160c 354 Gene3D G3DSA:2.40.30.170 205 291 4.2E-9 T 12-10-2018 AFR_31430 cbd6bf72c8ec483235e77ed68dcac4cb 387 SUPERFAMILY SSF46785 12 73 4.36E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31430 cbd6bf72c8ec483235e77ed68dcac4cb 387 SUPERFAMILY SSF53067 83 374 1.03E-33 T 12-10-2018 AFR_31430 cbd6bf72c8ec483235e77ed68dcac4cb 387 Gene3D G3DSA:3.30.420.40 182 375 3.6E-35 T 12-10-2018 AFR_31430 cbd6bf72c8ec483235e77ed68dcac4cb 387 Gene3D G3DSA:1.10.10.10 10 77 1.5E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31430 cbd6bf72c8ec483235e77ed68dcac4cb 387 ProSitePatterns PS01125 ROK family signature. 207 234 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_31430 cbd6bf72c8ec483235e77ed68dcac4cb 387 Pfam PF00480 ROK family 99 371 1.4E-36 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_31430 cbd6bf72c8ec483235e77ed68dcac4cb 387 Gene3D G3DSA:3.30.420.40 78 181 1.0E-7 T 12-10-2018 AFR_16450 aacd3b34beabbe691303afb947c5ac42 190 SUPERFAMILY SSF55729 1 180 8.68E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_16450 aacd3b34beabbe691303afb947c5ac42 190 Gene3D G3DSA:3.40.630.30 1 176 1.4E-34 T 12-10-2018 AFR_16450 aacd3b34beabbe691303afb947c5ac42 190 Pfam PF13527 Acetyltransferase (GNAT) domain 2 127 6.4E-11 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 582 598 2.5E-49 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 690 709 2.5E-49 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 348 367 2.5E-49 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 713 731 2.5E-49 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 660 679 2.5E-49 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 PIRSF PIRSF001174 1 761 2.2E-246 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Gene3D G3DSA:1.20.58.1480 108 230 2.7E-25 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 344 479 9.3E-20 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 SUPERFAMILY SSF54211 582 756 4.93E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 663 671 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 557 759 1.1E-81 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Gene3D G3DSA:3.40.50.300 296 483 2.8E-60 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Gene3D G3DSA:1.10.8.60 484 571 5.0E-23 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Gene3D G3DSA:3.30.230.10 581 763 4.3E-74 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 SMART SM00464 5 187 2.4E-25 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 TIGRFAM TIGR00763 lon: endopeptidase La 8 757 7.9E-241 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Gene3D G3DSA:2.30.130.40 1 105 1.8E-7 T 12-10-2018 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 185 3.1E-16 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 Hamap MF_01973 Lon protease [lon]. 6 759 59.109 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 SMART SM00382 340 485 1.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 SUPERFAMILY SSF88697 5 185 7.95E-17 T 12-10-2018 IPR015947 PUA-like superfamily AFR_13465 d97c2a8466de4ca3f8c853751b0f0526 769 SUPERFAMILY SSF52540 290 567 1.8E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16990 019bfa786f7724476b180ff61f6774ef 251 Gene3D G3DSA:3.40.630.30 12 200 1.0E-24 T 12-10-2018 AFR_16990 019bfa786f7724476b180ff61f6774ef 251 SUPERFAMILY SSF55729 35 149 4.65E-5 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05210 936adcfc524558ef7050b240d380e29a 507 Pfam PF01583 Adenylylsulphate kinase 326 482 2.9E-55 T 12-10-2018 AFR_05210 936adcfc524558ef7050b240d380e29a 507 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 321 495 5.9E-52 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFR_05210 936adcfc524558ef7050b240d380e29a 507 SUPERFAMILY SSF52540 325 498 2.54E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05210 936adcfc524558ef7050b240d380e29a 507 SUPERFAMILY SSF52374 132 321 4.5E-14 T 12-10-2018 AFR_05210 936adcfc524558ef7050b240d380e29a 507 SUPERFAMILY SSF88697 13 114 8.45E-15 T 12-10-2018 IPR015947 PUA-like superfamily AFR_05210 936adcfc524558ef7050b240d380e29a 507 Gene3D G3DSA:3.10.400.10 8 129 1.1E-20 T 12-10-2018 AFR_05210 936adcfc524558ef7050b240d380e29a 507 Gene3D G3DSA:3.40.50.300 320 506 1.8E-64 T 12-10-2018 AFR_05210 936adcfc524558ef7050b240d380e29a 507 Pfam PF01747 ATP-sulfurylase 134 246 7.5E-11 T 12-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFR_05210 936adcfc524558ef7050b240d380e29a 507 Pfam PF14306 PUA-like domain 16 110 2.9E-13 T 12-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFR_05210 936adcfc524558ef7050b240d380e29a 507 Gene3D G3DSA:3.40.50.620 132 319 1.6E-19 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_41735 706fe29df50de9f9ae6e6d14d1b261e2 245 Gene3D G3DSA:2.60.40.1240 109 234 1.5E-33 T 12-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily AFR_41735 706fe29df50de9f9ae6e6d14d1b261e2 245 Pfam PF11611 Domain of unknown function (DUF4352) 116 239 7.1E-32 T 12-10-2018 IPR029051 Domain of unknown function DUF4352 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 Pfam PF01197 Ribosomal protein L31 1 79 1.0E-27 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 Gene3D G3DSA:2.30.170.50 1 83 3.6E-23 T 12-10-2018 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 SUPERFAMILY SSF143800 1 79 1.69E-21 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.0E-16 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 PRINTS PR01249 Ribosomal protein L31 signature 45 60 3.0E-16 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 PRINTS PR01249 Ribosomal protein L31 signature 60 78 3.0E-16 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 1.8E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_18995 2f8838a3ff7a932c828d9dd7b577f8e1 85 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 24.242 T 12-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_35865 b2af9d31056830679e30d6b4e1bfb88f 184 Gene3D G3DSA:3.40.630.30 6 183 5.0E-29 T 12-10-2018 AFR_35865 b2af9d31056830679e30d6b4e1bfb88f 184 SUPERFAMILY SSF55729 6 173 3.14E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35865 b2af9d31056830679e30d6b4e1bfb88f 184 Pfam PF00583 Acetyltransferase (GNAT) family 60 153 2.3E-4 T 12-10-2018 IPR000182 GNAT domain AFR_14460 1551faa4d4595a588341686b9fb763d4 334 Gene3D G3DSA:1.10.10.10 1 88 5.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14460 1551faa4d4595a588341686b9fb763d4 334 Gene3D G3DSA:3.40.190.10 173 269 1.3E-47 T 12-10-2018 AFR_14460 1551faa4d4595a588341686b9fb763d4 334 Gene3D G3DSA:3.40.190.10 90 294 1.3E-47 T 12-10-2018 AFR_14460 1551faa4d4595a588341686b9fb763d4 334 SUPERFAMILY SSF46785 3 85 1.0E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_14460 1551faa4d4595a588341686b9fb763d4 334 Pfam PF03466 LysR substrate binding domain 99 298 6.5E-13 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_14460 1551faa4d4595a588341686b9fb763d4 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_14460 1551faa4d4595a588341686b9fb763d4 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_14460 1551faa4d4595a588341686b9fb763d4 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_14460 1551faa4d4595a588341686b9fb763d4 334 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_14460 1551faa4d4595a588341686b9fb763d4 334 SUPERFAMILY SSF53850 90 295 1.65E-25 T 12-10-2018 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SMART SM00873 218 391 7.5E-89 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Gene3D G3DSA:3.30.56.10 7 184 1.8E-56 T 12-10-2018 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Pfam PF03484 tRNA synthetase B5 domain 417 474 1.1E-14 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Pfam PF01588 Putative tRNA binding domain 48 146 1.1E-17 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Gene3D G3DSA:3.50.40.10 204 400 3.8E-78 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Pfam PF03483 B3/4 domain 218 391 1.9E-70 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Gene3D G3DSA:3.30.70.380 731 823 2.4E-24 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 823 1.0E-185 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SUPERFAMILY SSF56037 206 403 7.85E-71 T 12-10-2018 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SUPERFAMILY SSF50249 40 200 6.37E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SUPERFAMILY SSF54991 726 823 1.02E-24 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Pfam PF03147 Ferredoxin-fold anticodon binding domain 730 823 1.5E-22 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SUPERFAMILY SSF55681 470 718 6.46E-44 T 12-10-2018 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SUPERFAMILY SSF46955 409 478 2.01E-13 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Gene3D G3DSA:2.40.50.140 41 159 1.8E-56 T 12-10-2018 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SMART SM00896 730 823 8.8E-38 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 SMART SM00874 407 474 4.2E-20 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Gene3D G3DSA:3.30.56.10 407 478 6.7E-17 T 12-10-2018 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 817 39.895 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFR_30440 8d7f48e3ee1cfdbd771a88bbf8d7960a 825 Gene3D G3DSA:3.30.930.10 489 719 5.5E-56 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 SUPERFAMILY SSF51905 1 335 2.33E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.5E-37 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 1.5E-37 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 1.5E-37 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 1.5E-37 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.5E-37 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 326 5.0E-66 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 1.2E-34 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 Gene3D G3DSA:3.50.50.60 148 269 5.8E-123 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 SUPERFAMILY SSF55424 343 465 2.06E-38 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 Gene3D G3DSA:3.50.50.60 5 331 5.8E-123 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PIRSF PIRSF000350 1 461 9.3E-89 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 465 2.7E-167 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 2.4E-66 T 12-10-2018 AFR_25210 491be99a1490e4c403a9f06aba739a5b 466 Gene3D G3DSA:3.30.390.30 345 466 4.4E-45 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_28020 126f1578abc3136c37f15159485c7001 373 Gene3D G3DSA:3.30.9.30 32 254 8.2E-82 T 12-10-2018 AFR_28020 126f1578abc3136c37f15159485c7001 373 SUPERFAMILY SSF51905 1 357 2.45E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_28020 126f1578abc3136c37f15159485c7001 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 6.7E-10 T 12-10-2018 AFR_28020 126f1578abc3136c37f15159485c7001 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 294 6.7E-10 T 12-10-2018 AFR_28020 126f1578abc3136c37f15159485c7001 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 263 278 6.7E-10 T 12-10-2018 AFR_28020 126f1578abc3136c37f15159485c7001 373 Pfam PF01494 FAD binding domain 1 325 9.8E-24 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_28020 126f1578abc3136c37f15159485c7001 373 Gene3D G3DSA:3.50.50.60 1 325 8.2E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_03645 c491da9c112559308f1a625c9550e57e 167 Gene3D G3DSA:3.30.1060.10 2 167 1.7E-70 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_03645 c491da9c112559308f1a625c9550e57e 167 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 4 152 2.3E-49 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_03645 c491da9c112559308f1a625c9550e57e 167 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 158 33.768 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_03645 c491da9c112559308f1a625c9550e57e 167 Pfam PF01625 Peptide methionine sulfoxide reductase 5 152 1.9E-55 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_03645 c491da9c112559308f1a625c9550e57e 167 SUPERFAMILY SSF55068 3 161 5.36E-64 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_06870 ba1c8aa008c5162d0cbdadc6b809960c 294 Gene3D G3DSA:3.30.460.20 1 105 6.7E-15 T 12-10-2018 AFR_06870 ba1c8aa008c5162d0cbdadc6b809960c 294 Gene3D G3DSA:1.20.58.340 217 294 1.2E-22 T 12-10-2018 AFR_06870 ba1c8aa008c5162d0cbdadc6b809960c 294 Pfam PF01544 CorA-like Mg2+ transporter protein 1 286 9.3E-48 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFR_06870 ba1c8aa008c5162d0cbdadc6b809960c 294 Gene3D G3DSA:1.20.58.340 106 216 9.3E-22 T 12-10-2018 AFR_06870 ba1c8aa008c5162d0cbdadc6b809960c 294 SUPERFAMILY SSF143865 1 227 3.66E-43 T 12-10-2018 AFR_06870 ba1c8aa008c5162d0cbdadc6b809960c 294 SUPERFAMILY SSF144083 229 290 6.8E-18 T 12-10-2018 AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 SUPERFAMILY SSF55781 26 171 9.38E-21 T 12-10-2018 AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 SUPERFAMILY SSF52172 160 230 8.95E-9 T 12-10-2018 IPR011006 CheY-like superfamily AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 Gene3D G3DSA:1.10.10.10 177 236 1.0E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 SMART SM00065 26 173 1.2E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 Pfam PF03861 ANTAR domain 178 230 8.4E-19 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 PIRSF PIRSF036625 1 239 1.7E-54 T 12-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 Pfam PF13185 GAF domain 25 163 3.6E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 Gene3D G3DSA:3.30.450.40 10 174 2.7E-23 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_27980 072cd98fc1593e9ef78eb67a9c047f96 239 SMART SM01012 175 230 3.4E-20 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_20475 ce26cb33280f68f78f9c357c0525eec7 204 SUPERFAMILY SSF52218 5 179 7.68E-31 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_20475 ce26cb33280f68f78f9c357c0525eec7 204 Pfam PF03358 NADPH-dependent FMN reductase 6 155 1.4E-37 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_20475 ce26cb33280f68f78f9c357c0525eec7 204 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 6 201 1.7E-81 T 12-10-2018 IPR023932 Uncharacterised protein family, CE1759 AFR_20475 ce26cb33280f68f78f9c357c0525eec7 204 Gene3D G3DSA:3.40.50.360 1 181 4.2E-53 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 PRINTS PR00143 Citrate synthase signature 239 267 6.5E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 PRINTS PR00143 Citrate synthase signature 378 392 6.5E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 PRINTS PR00143 Citrate synthase signature 217 232 6.5E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 PRINTS PR00143 Citrate synthase signature 295 315 6.5E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 PRINTS PR00143 Citrate synthase signature 358 374 6.5E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 PRINTS PR00143 Citrate synthase signature 163 176 6.5E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 Gene3D G3DSA:1.10.230.10 266 375 2.8E-136 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 ProSitePatterns PS00480 Citrate synthase signature. 302 314 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 PIRSF PIRSF001369 35 427 4.9E-153 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 Gene3D G3DSA:2.20.28.60 2 48 3.2E-14 T 12-10-2018 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 13 420 7.0E-178 T 12-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 SUPERFAMILY SSF48256 9 427 5.23E-153 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 Pfam PF00285 Citrate synthase, C-terminal domain 44 410 4.5E-131 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_26960 7b644bb4269fe55dbde5aeef088df4ed 427 Gene3D G3DSA:1.10.580.10 55 410 2.8E-136 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_33260 b79a9ff5779db4138b52c3140a00949a 427 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 27 407 1.9E-92 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 AFR_33260 b79a9ff5779db4138b52c3140a00949a 427 Pfam PF07690 Major Facilitator Superfamily 35 376 3.3E-35 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_33260 b79a9ff5779db4138b52c3140a00949a 427 Gene3D G3DSA:1.20.1720.10 29 409 2.7E-99 T 12-10-2018 AFR_33260 b79a9ff5779db4138b52c3140a00949a 427 SUPERFAMILY SSF103473 15 417 1.19E-57 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_33260 b79a9ff5779db4138b52c3140a00949a 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 99 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_12395 7e79ad80b695b76e22b3e19ab6337c53 135 Pfam PF08281 Sigma-70, region 4 74 123 2.4E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_12395 7e79ad80b695b76e22b3e19ab6337c53 135 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 1 128 3.5E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_12395 7e79ad80b695b76e22b3e19ab6337c53 135 SUPERFAMILY SSF88946 1 59 2.47E-8 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_12395 7e79ad80b695b76e22b3e19ab6337c53 135 Gene3D G3DSA:1.10.1740.10 1 45 9.4E-7 T 12-10-2018 AFR_12395 7e79ad80b695b76e22b3e19ab6337c53 135 SUPERFAMILY SSF88659 69 128 4.8E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_12395 7e79ad80b695b76e22b3e19ab6337c53 135 Gene3D G3DSA:1.10.10.10 69 132 4.0E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37210 288b19006d88f048f72e0c256061f051 394 SUPERFAMILY SSF53901 5 269 6.48E-81 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_37210 288b19006d88f048f72e0c256061f051 394 SUPERFAMILY SSF53901 271 390 8.86E-34 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_37210 288b19006d88f048f72e0c256061f051 394 Pfam PF00108 Thiolase, N-terminal domain 5 261 1.8E-92 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFR_37210 288b19006d88f048f72e0c256061f051 394 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 AFR_37210 288b19006d88f048f72e0c256061f051 394 Gene3D G3DSA:3.40.47.10 5 275 3.3E-139 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_37210 288b19006d88f048f72e0c256061f051 394 Pfam PF02803 Thiolase, C-terminal domain 270 390 1.7E-42 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFR_37210 288b19006d88f048f72e0c256061f051 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 1.4E-131 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_37210 288b19006d88f048f72e0c256061f051 394 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFR_37210 288b19006d88f048f72e0c256061f051 394 Gene3D G3DSA:3.40.47.10 126 389 3.3E-139 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_37210 288b19006d88f048f72e0c256061f051 394 PIRSF PIRSF000429 2 393 1.4E-118 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_37210 288b19006d88f048f72e0c256061f051 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Gene3D G3DSA:3.40.50.300 257 432 6.1E-56 T 12-10-2018 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 SMART SM00487 72 263 1.4E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 629 706 1.4E-19 T 12-10-2018 IPR011709 Domain of unknown function DUF1605 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Gene3D G3DSA:3.40.50.300 31 256 5.2E-76 T 12-10-2018 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 SUPERFAMILY SSF52540 74 606 2.52E-107 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Pfam PF04408 Helicase associated domain (HA2) 477 561 3.0E-18 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Pfam PF00270 DEAD/DEAH box helicase 87 233 2.1E-6 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 SMART SM00847 475 564 7.7E-37 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Pfam PF11898 Domain of unknown function (DUF3418) 720 1304 9.6E-229 T 12-10-2018 IPR024590 RNA helicase HrpA, C-terminal AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 SMART SM00490 315 415 6.4E-15 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Gene3D G3DSA:1.20.120.1080 460 554 4.9E-19 T 12-10-2018 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 Pfam PF00271 Helicase conserved C-terminal domain 298 414 1.4E-11 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 19 1304 0.0 T 12-10-2018 IPR010222 RNA helicase HrpA GO:0004004 AFR_27015 4162e4c0168bf80bfff2957e13543169 1307 SMART SM00382 92 395 6.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22670 4969199d6dd6b0c1b60388d6c79c5550 378 PIRSF PIRSF015578 1 376 1.4E-79 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFR_22670 4969199d6dd6b0c1b60388d6c79c5550 378 SUPERFAMILY SSF55347 213 317 9.81E-28 T 12-10-2018 AFR_22670 4969199d6dd6b0c1b60388d6c79c5550 378 Pfam PF01658 Myo-inositol-1-phosphate synthase 214 318 9.7E-25 T 12-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFR_22670 4969199d6dd6b0c1b60388d6c79c5550 378 Gene3D G3DSA:3.40.50.720 6 366 2.2E-115 T 12-10-2018 AFR_22670 4969199d6dd6b0c1b60388d6c79c5550 378 Gene3D G3DSA:3.30.360.10 214 314 2.2E-115 T 12-10-2018 AFR_22670 4969199d6dd6b0c1b60388d6c79c5550 378 Pfam PF07994 Myo-inositol-1-phosphate synthase 3 367 2.2E-38 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFR_22670 4969199d6dd6b0c1b60388d6c79c5550 378 SUPERFAMILY SSF51735 4 372 1.81E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_27515 352f0eb250060d190afaee46ad18367d 584 SUPERFAMILY SSF51905 303 490 7.77E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27515 352f0eb250060d190afaee46ad18367d 584 Gene3D G3DSA:3.50.50.60 141 408 2.1E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27515 352f0eb250060d190afaee46ad18367d 584 Gene3D G3DSA:3.50.50.60 428 526 5.9E-6 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27515 352f0eb250060d190afaee46ad18367d 584 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 154 349 2.6E-18 T 12-10-2018 AFR_27515 352f0eb250060d190afaee46ad18367d 584 SUPERFAMILY SSF51905 153 352 6.65E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27515 352f0eb250060d190afaee46ad18367d 584 Gene3D G3DSA:3.10.450.50 1 127 3.2E-5 T 12-10-2018 AFR_27515 352f0eb250060d190afaee46ad18367d 584 SUPERFAMILY SSF54427 2 107 3.29E-7 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_27515 352f0eb250060d190afaee46ad18367d 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 285 5.6E-9 T 12-10-2018 AFR_27515 352f0eb250060d190afaee46ad18367d 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 174 5.6E-9 T 12-10-2018 AFR_27515 352f0eb250060d190afaee46ad18367d 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 342 5.6E-9 T 12-10-2018 AFR_28395 30d64fec913c427537af6fd9409c92bf 197 SUPERFAMILY SSF46689 2 83 6.16E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_28395 30d64fec913c427537af6fd9409c92bf 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28395 30d64fec913c427537af6fd9409c92bf 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28395 30d64fec913c427537af6fd9409c92bf 197 Gene3D G3DSA:1.10.357.10 2 196 8.0E-28 T 12-10-2018 AFR_28395 30d64fec913c427537af6fd9409c92bf 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.4E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_41760 2f1978cefd72eae1226b4ef26e8b2ac2 220 Pfam PF07510 Protein of unknown function (DUF1524) 103 215 2.9E-11 T 12-10-2018 IPR011089 Domain of unknown function DUF1524 AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 2.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 127 2.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 2.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 Gene3D G3DSA:3.40.50.720 1 220 6.8E-47 T 12-10-2018 AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 5.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 5.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 5.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 5.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 SUPERFAMILY SSF51735 1 182 9.2E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_05250 ab7205cb2e947aa1c12dba05e80f4008 230 Pfam PF00106 short chain dehydrogenase 7 178 4.7E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 Gene3D G3DSA:1.20.1270.50 535 631 4.3E-26 T 12-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 268 518 9.0E-80 T 12-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 Gene3D G3DSA:2.70.98.30 725 899 1.2E-7 T 12-10-2018 AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 SUPERFAMILY SSF88688 531 638 3.04E-28 T 12-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 SUPERFAMILY SSF74650 672 1013 1.73E-52 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 Gene3D G3DSA:3.20.110.10 263 533 1.2E-54 T 12-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 670 1010 8.6E-48 T 12-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 SUPERFAMILY SSF88713 261 530 1.78E-72 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 SMART SM00872 532 610 7.0E-38 T 12-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 AFR_13120 0eb69c375ad9d705e492032314d24d94 1018 Pfam PF09261 Alpha mannosidase middle domain 532 610 1.0E-26 T 12-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 Pfam PF02910 Fumarate reductase flavoprotein C-term 488 601 2.6E-22 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 Gene3D G3DSA:1.20.58.100 460 573 1.0E-30 T 12-10-2018 AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 SUPERFAMILY SSF51905 3 471 2.72E-68 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 SUPERFAMILY SSF46977 478 629 9.94E-41 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 PIRSF PIRSF000171 1 607 4.9E-36 T 12-10-2018 AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 Gene3D G3DSA:3.50.50.60 11 444 1.1E-144 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 Gene3D G3DSA:3.90.700.10 254 396 1.1E-144 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 Pfam PF00890 FAD binding domain 11 432 3.9E-90 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_38820 9125cf0728a27479096bcf3e14bcb6da 636 SUPERFAMILY SSF56425 244 390 5.83E-33 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_31200 871baa73ab10c2dfaa2c1ce7d834009c 261 SUPERFAMILY SSF53335 20 233 3.34E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_31200 871baa73ab10c2dfaa2c1ce7d834009c 261 Pfam PF13649 Methyltransferase domain 33 121 7.3E-16 T 12-10-2018 AFR_31200 871baa73ab10c2dfaa2c1ce7d834009c 261 Gene3D G3DSA:3.40.50.150 7 253 4.3E-80 T 12-10-2018 AFR_31200 871baa73ab10c2dfaa2c1ce7d834009c 261 Gene3D G3DSA:1.10.150.290 130 237 4.3E-80 T 12-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 AFR_35945 f89bd0693026cb7a1268ec47c7803de7 298 Pfam PF12802 MarR family 191 244 2.9E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_35945 f89bd0693026cb7a1268ec47c7803de7 298 Gene3D G3DSA:1.10.10.10 181 295 2.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35945 f89bd0693026cb7a1268ec47c7803de7 298 SMART SM00347 183 280 3.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_35945 f89bd0693026cb7a1268ec47c7803de7 298 SUPERFAMILY SSF46785 188 294 4.25E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 SUPERFAMILY SSF51735 6 252 3.57E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 Gene3D G3DSA:3.40.50.720 1 259 2.2E-74 T 12-10-2018 AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 7.9E-59 T 12-10-2018 AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15700 ee33d9e5dc40fdac68bbabe41fa63ce8 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02490 119101dd26059e62dde8f7bde46193a6 6085 SUPERFAMILY SSF56399 5039 5273 1.25E-11 T 12-10-2018 AFR_02490 119101dd26059e62dde8f7bde46193a6 6085 Gene3D G3DSA:3.90.176.10 5921 6058 9.4E-18 T 12-10-2018 AFR_02490 119101dd26059e62dde8f7bde46193a6 6085 SUPERFAMILY SSF56399 5812 6058 1.53E-11 T 12-10-2018 AFR_02490 119101dd26059e62dde8f7bde46193a6 6085 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 146 243 2.1E-13 T 12-10-2018 IPR028908 Tox-PL domain AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 SUPERFAMILY SSF55073 460 610 5.57E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 Pfam PF00990 Diguanylate cyclase, GGDEF domain 455 608 8.9E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 Gene3D G3DSA:3.30.450.40 302 450 4.9E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 Pfam PF00563 EAL domain 630 864 1.3E-71 T 12-10-2018 IPR001633 EAL domain AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 SMART SM00267 444 614 1.9E-51 T 12-10-2018 IPR000160 GGDEF domain AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 SUPERFAMILY SSF55781 302 452 1.14E-7 T 12-10-2018 AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 Gene3D G3DSA:3.20.20.450 625 885 1.5E-98 T 12-10-2018 IPR035919 EAL domain superfamily AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 SUPERFAMILY SSF141868 630 876 1.12E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 452 608 4.2E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 SMART SM00052 624 869 5.0E-113 T 12-10-2018 IPR001633 EAL domain AFR_27055 5364f7bad9c731e0e3b7c66fc24af116 886 Gene3D G3DSA:3.30.70.270 451 617 5.1E-50 T 12-10-2018 AFR_37690 25f340a49e68ac43e552a30ef84714ab 334 SUPERFAMILY SSF46689 280 331 1.93E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37690 25f340a49e68ac43e552a30ef84714ab 334 SUPERFAMILY SSF46689 228 278 1.15E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37690 25f340a49e68ac43e552a30ef84714ab 334 SMART SM00342 244 330 3.9E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_37690 25f340a49e68ac43e552a30ef84714ab 334 Pfam PF12833 Helix-turn-helix domain 250 331 2.2E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_37690 25f340a49e68ac43e552a30ef84714ab 334 Pfam PF14525 AraC-binding-like domain 30 208 1.4E-33 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_37690 25f340a49e68ac43e552a30ef84714ab 334 Gene3D G3DSA:1.10.10.60 228 334 8.0E-32 T 12-10-2018 AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 5 496 2.3E-141 T 12-10-2018 IPR004482 Mg chelatase-related protein AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 SMART SM00382 205 388 1.7E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 Gene3D G3DSA:3.30.230.10 29 165 4.5E-15 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 Pfam PF13541 Subunit ChlI of Mg-chelatase 16 138 2.0E-39 T 12-10-2018 AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 400 496 2.3E-21 T 12-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 Pfam PF01078 Magnesium chelatase, subunit ChlI 185 391 2.2E-83 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 SUPERFAMILY SSF54211 3 165 4.93E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 Gene3D G3DSA:3.40.50.300 187 419 1.7E-38 T 12-10-2018 AFR_36235 403caf93d5a95591c23e9348ecf1af7d 505 SUPERFAMILY SSF52540 185 499 4.89E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 Pfam PF00072 Response regulator receiver domain 4 116 4.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 SUPERFAMILY SSF46894 141 218 7.82E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 5.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 5.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 5.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 SUPERFAMILY SSF52172 2 134 4.7E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 SMART SM00421 155 212 1.5E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 SMART SM00448 2 115 2.0E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 5.8E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25645 f9b685b3e6252d36270eb72549f72ec3 222 Gene3D G3DSA:3.40.50.12740 2 218 2.9E-70 T 12-10-2018 AFR_22305 5889c6e34b2f969ebc380c4004f0433b 315 Gene3D G3DSA:1.10.8.450 237 269 5.5E-85 T 12-10-2018 AFR_22305 5889c6e34b2f969ebc380c4004f0433b 315 Gene3D G3DSA:3.40.190.10 36 301 5.5E-85 T 12-10-2018 AFR_22305 5889c6e34b2f969ebc380c4004f0433b 315 Pfam PF09084 NMT1/THI5 like 70 245 2.7E-12 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_22305 5889c6e34b2f969ebc380c4004f0433b 315 SUPERFAMILY SSF53850 38 258 2.12E-39 T 12-10-2018 AFR_22305 5889c6e34b2f969ebc380c4004f0433b 315 SMART SM00062 35 248 8.6E-5 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_22305 5889c6e34b2f969ebc380c4004f0433b 315 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 58 311 6.4E-59 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 AFR_22305 5889c6e34b2f969ebc380c4004f0433b 315 Gene3D G3DSA:3.40.190.10 107 205 5.5E-85 T 12-10-2018 AFR_03140 c34d9ae18d1066990bb4235c6f14a540 987 SUPERFAMILY SSF49785 897 977 4.82E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_03140 c34d9ae18d1066990bb4235c6f14a540 987 Pfam PF00754 F5/8 type C domain 611 688 1.7E-16 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_03140 c34d9ae18d1066990bb4235c6f14a540 987 Gene3D G3DSA:2.60.120.260 604 722 3.1E-20 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_03140 c34d9ae18d1066990bb4235c6f14a540 987 Gene3D G3DSA:2.60.120.260 888 972 1.5E-8 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_03140 c34d9ae18d1066990bb4235c6f14a540 987 SUPERFAMILY SSF49785 602 698 6.31E-19 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32090 795bbed7c6d645e83b54376307f07ad8 442 SUPERFAMILY SSF50998 56 328 5.1E-16 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_32090 795bbed7c6d645e83b54376307f07ad8 442 SMART SM00564 70 104 2.5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFR_32090 795bbed7c6d645e83b54376307f07ad8 442 SMART SM00564 165 203 47.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFR_32090 795bbed7c6d645e83b54376307f07ad8 442 Pfam PF13360 PQQ-like domain 136 326 3.1E-11 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_32090 795bbed7c6d645e83b54376307f07ad8 442 Gene3D G3DSA:2.130.10.10 37 305 1.6E-19 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_11485 1688e372714a576ded704d8b06b5c07a 267 Gene3D G3DSA:3.40.710.10 1 264 7.7E-58 T 12-10-2018 AFR_11485 1688e372714a576ded704d8b06b5c07a 267 Pfam PF00144 Beta-lactamase 1 251 2.1E-45 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_11485 1688e372714a576ded704d8b06b5c07a 267 SUPERFAMILY SSF56601 1 259 7.24E-57 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_23045 798cfb05478c0087021cb4719fab1b0a 205 Gene3D G3DSA:3.10.180.10 2 139 1.5E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_23045 798cfb05478c0087021cb4719fab1b0a 205 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 135 6.4E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_23045 798cfb05478c0087021cb4719fab1b0a 205 SUPERFAMILY SSF54593 3 143 9.93E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 SUPERFAMILY SSF49785 134 261 3.04E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 Gene3D G3DSA:2.60.120.260 283 420 2.5E-34 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 SUPERFAMILY SSF51011 835 917 1.29E-18 T 12-10-2018 AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 SMART SM00606 128 263 9.1E-4 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 SUPERFAMILY SSF49785 283 413 4.5E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 Gene3D G3DSA:2.60.120.260 135 261 2.2E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 Pfam PF16990 Carbohydrate binding module (family 35) 284 397 2.9E-8 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 Pfam PF16990 Carbohydrate binding module (family 35) 135 261 7.4E-11 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 Gene3D G3DSA:2.60.40.1180 867 918 1.1E-14 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 Gene3D G3DSA:3.20.20.80 492 866 2.7E-75 T 12-10-2018 AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 Pfam PF01055 Glycosyl hydrolases family 31 485 918 3.8E-79 T 12-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 AFR_28450 a1ac2cd9426668f7dd370dc2aa7f85c6 923 SUPERFAMILY SSF51445 495 834 4.81E-41 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 Pfam PF03924 CHASE domain 83 256 4.5E-15 T 12-10-2018 IPR006189 CHASE domain AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 SUPERFAMILY SSF141868 543 777 2.09E-85 T 12-10-2018 IPR035919 EAL domain superfamily AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 Pfam PF00990 Diguanylate cyclase, GGDEF domain 369 520 2.7E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 365 525 5.8E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 SMART SM01079 76 264 0.004 T 12-10-2018 IPR006189 CHASE domain AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 SMART SM00052 536 776 2.8E-117 T 12-10-2018 IPR001633 EAL domain AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 Pfam PF00563 EAL domain 544 771 3.3E-75 T 12-10-2018 IPR001633 EAL domain AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 Gene3D G3DSA:3.20.20.450 536 782 1.7E-95 T 12-10-2018 IPR035919 EAL domain superfamily AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 SUPERFAMILY SSF55073 374 528 4.45E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 Gene3D G3DSA:3.30.70.270 363 530 6.5E-53 T 12-10-2018 AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 SMART SM00267 358 526 3.1E-59 T 12-10-2018 IPR000160 GGDEF domain AFR_35390 6769e7f11b4eec8b27e94b455d42c0ac 793 Gene3D G3DSA:3.30.450.350 82 290 4.2E-6 T 12-10-2018 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 Gene3D G3DSA:2.40.30.10 1 93 3.1E-20 T 12-10-2018 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 Pfam PF00970 Oxidoreductase FAD-binding domain 23 94 9.3E-14 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 SUPERFAMILY SSF52343 85 228 3.54E-33 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 PRINTS PR00410 Phenol hydroxylase reductase family signature 89 98 4.3E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 PRINTS PR00410 Phenol hydroxylase reductase family signature 198 206 4.3E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 PRINTS PR00410 Phenol hydroxylase reductase family signature 105 124 4.3E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 PRINTS PR00410 Phenol hydroxylase reductase family signature 24 36 4.3E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 44 51 5.5E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 24 34 5.5E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 105 124 5.5E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 SUPERFAMILY SSF63380 1 98 1.7E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 Gene3D G3DSA:3.40.50.80 99 233 7.7E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_32390 070c4f68e73662b4a3ec38f1bf7249e0 234 Pfam PF00175 Oxidoreductase NAD-binding domain 106 212 1.8E-11 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 307 319 9.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 291 307 9.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 277 291 9.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 Gene3D G3DSA:1.10.10.10 267 334 5.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23600 3533858734f42950ddcb2769fc3891ff 336 Pfam PF12697 Alpha/beta hydrolase family 40 259 6.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 5.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 5.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 5.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 5.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 SUPERFAMILY SSF46894 264 332 4.08E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 Pfam PF00196 Bacterial regulatory proteins, luxR family 277 330 1.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23600 3533858734f42950ddcb2769fc3891ff 336 SUPERFAMILY SSF53474 7 265 4.74E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23600 3533858734f42950ddcb2769fc3891ff 336 Gene3D G3DSA:3.40.50.1820 2 266 5.2E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23600 3533858734f42950ddcb2769fc3891ff 336 SMART SM00421 274 331 8.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16085 74ba2561209ed7607c2fe920fc892499 318 Pfam PF03466 LysR substrate binding domain 108 299 3.4E-18 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_16085 74ba2561209ed7607c2fe920fc892499 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 8.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_16085 74ba2561209ed7607c2fe920fc892499 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 8.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_16085 74ba2561209ed7607c2fe920fc892499 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 8.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_16085 74ba2561209ed7607c2fe920fc892499 318 Gene3D G3DSA:1.10.10.10 6 92 5.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16085 74ba2561209ed7607c2fe920fc892499 318 Gene3D G3DSA:3.40.190.10 108 286 2.3E-17 T 12-10-2018 AFR_16085 74ba2561209ed7607c2fe920fc892499 318 SUPERFAMILY SSF46785 8 88 6.49E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16085 74ba2561209ed7607c2fe920fc892499 318 Gene3D G3DSA:3.40.190.10 170 274 2.3E-17 T 12-10-2018 AFR_16085 74ba2561209ed7607c2fe920fc892499 318 SUPERFAMILY SSF53850 108 301 3.1E-21 T 12-10-2018 AFR_16085 74ba2561209ed7607c2fe920fc892499 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.3E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11630 168553155554e3ea1e9216fee7a5c2bb 214 Pfam PF02397 Bacterial sugar transferase 10 189 3.3E-59 T 12-10-2018 IPR003362 Bacterial sugar transferase AFR_17930 9216f9c22d8dbda1ef50c600c2c7f2dc 157 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 1.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_17930 9216f9c22d8dbda1ef50c600c2c7f2dc 157 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 1.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_17930 9216f9c22d8dbda1ef50c600c2c7f2dc 157 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 1.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_17930 9216f9c22d8dbda1ef50c600c2c7f2dc 157 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 57 1.3E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_17930 9216f9c22d8dbda1ef50c600c2c7f2dc 157 SUPERFAMILY SSF46785 1 79 1.01E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17930 9216f9c22d8dbda1ef50c600c2c7f2dc 157 Gene3D G3DSA:1.10.10.10 1 80 6.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1975 2055 5.9E-16 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 SUPERFAMILY SSF50370 1754 1877 4.55E-19 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 Gene3D G3DSA:2.180.10.10 1439 1754 2.7E-11 T 12-10-2018 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 Gene3D G3DSA:2.180.10.10 1874 2055 1.3E-13 T 12-10-2018 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 Pfam PF07591 Pretoxin HINT domain 2285 2423 9.4E-15 T 12-10-2018 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 Gene3D G3DSA:2.170.16.10 2274 2423 2.5E-39 T 12-10-2018 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 SMART SM00306 2275 2380 7.0E-14 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 SUPERFAMILY SSF51294 2278 2422 9.55E-18 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1319 1362 0.001 T 12-10-2018 IPR006530 YD repeat AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 Gene3D G3DSA:2.80.10.50 1755 1873 5.6E-22 T 12-10-2018 AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 SMART SM00458 1747 1880 1.3E-10 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_03705 739d8dc8cb3b9cb2cfcb9408a200d9ea 2557 Pfam PF00652 Ricin-type beta-trefoil lectin domain 1754 1877 1.9E-15 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 Gene3D G3DSA:1.25.40.10 542 664 6.6E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 SUPERFAMILY SSF52200 8 117 2.75E-16 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 Gene3D G3DSA:3.40.50.10140 9 121 6.3E-15 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 Pfam PF13424 Tetratricopeptide repeat 589 654 2.0E-12 T 12-10-2018 AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 SUPERFAMILY SSF48452 556 655 1.21E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 SMART SM00255 9 141 0.0089 T 12-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 Gene3D G3DSA:3.40.50.300 172 320 9.2E-21 T 12-10-2018 AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 SUPERFAMILY SSF52540 170 414 6.88E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09155 cbcebf0a1daf83fafdfc485c474ad49a 664 Pfam PF13676 TIR domain 12 120 7.1E-24 T 12-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 AFR_25500 666b0036e268f9f9919defeb989eb850 348 Pfam PF00480 ROK family 16 341 1.8E-41 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_25500 666b0036e268f9f9919defeb989eb850 348 SUPERFAMILY SSF53067 15 343 3.24E-38 T 12-10-2018 AFR_25500 666b0036e268f9f9919defeb989eb850 348 ProSitePatterns PS01125 ROK family signature. 156 183 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_25500 666b0036e268f9f9919defeb989eb850 348 Gene3D G3DSA:3.30.420.40 148 317 2.0E-49 T 12-10-2018 AFR_25500 666b0036e268f9f9919defeb989eb850 348 Gene3D G3DSA:3.30.420.40 16 147 2.0E-49 T 12-10-2018 AFR_09570 3049d71175f6864ed72896713771f581 259 SUPERFAMILY SSF53474 23 256 4.65E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_09570 3049d71175f6864ed72896713771f581 259 Gene3D G3DSA:3.40.50.1820 22 256 2.2E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_09570 3049d71175f6864ed72896713771f581 259 Pfam PF12697 Alpha/beta hydrolase family 37 239 4.0E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18395 5cbfedb7c3590ced7541342771711ffb 874 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 632 854 7.4E-28 T 12-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain AFR_18395 5cbfedb7c3590ced7541342771711ffb 874 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 632 854 2.5E-20 T 12-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain AFR_18395 5cbfedb7c3590ced7541342771711ffb 874 Pfam PF04738 Lantibiotic dehydratase, C terminus 49 221 2.3E-19 T 12-10-2018 IPR006827 Lantibiotic dehydratase, N-terminal AFR_18395 5cbfedb7c3590ced7541342771711ffb 874 Pfam PF04738 Lantibiotic dehydratase, C terminus 235 569 1.6E-49 T 12-10-2018 IPR006827 Lantibiotic dehydratase, N-terminal AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 Pfam PF13377 Periplasmic binding protein-like domain 169 330 3.7E-28 T 12-10-2018 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 9.3E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 9.3E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 Gene3D G3DSA:3.40.50.2300 85 322 2.8E-36 T 12-10-2018 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 SUPERFAMILY SSF53822 58 323 4.07E-33 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 SMART SM00354 1 71 3.7E-24 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 8.4E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 SUPERFAMILY SSF47413 1 59 2.38E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 Gene3D G3DSA:3.40.50.2300 160 327 2.8E-36 T 12-10-2018 AFR_22460 a2d0854cd2460f742f9b6ca36346742b 335 Gene3D G3DSA:1.10.260.40 1 58 9.4E-23 T 12-10-2018 AFR_27185 fe819c5546162a097db59025de33ea65 299 SUPERFAMILY SSF52540 29 268 7.29E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27185 fe819c5546162a097db59025de33ea65 299 SMART SM00382 37 207 2.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_27185 fe819c5546162a097db59025de33ea65 299 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 41 192 9.8E-10 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_27185 fe819c5546162a097db59025de33ea65 299 Gene3D G3DSA:3.40.50.300 25 210 1.6E-27 T 12-10-2018 AFR_09240 c098ebdd1facc3de88679c820a202997 211 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFR_09240 c098ebdd1facc3de88679c820a202997 211 Gene3D G3DSA:3.30.930.10 2 210 1.3E-74 T 12-10-2018 AFR_09240 c098ebdd1facc3de88679c820a202997 211 Hamap MF_00013 Octanoyltransferase [lipB]. 7 210 30.81 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFR_09240 c098ebdd1facc3de88679c820a202997 211 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 129 1.0E-17 T 12-10-2018 AFR_09240 c098ebdd1facc3de88679c820a202997 211 SUPERFAMILY SSF55681 6 208 2.73E-64 T 12-10-2018 AFR_09240 c098ebdd1facc3de88679c820a202997 211 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 164 3.0E-9 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFR_09240 c098ebdd1facc3de88679c820a202997 211 PIRSF PIRSF016262 3 211 3.0E-57 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFR_09240 c098ebdd1facc3de88679c820a202997 211 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 37 197 1.4E-35 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFR_19825 147baf3e14c6c431e87b2e31d8d16545 168 Pfam PF13305 WHG domain 80 145 3.8E-10 T 12-10-2018 IPR025996 WHG domain AFR_19825 147baf3e14c6c431e87b2e31d8d16545 168 SUPERFAMILY SSF48498 76 162 1.16E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_19825 147baf3e14c6c431e87b2e31d8d16545 168 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19825 147baf3e14c6c431e87b2e31d8d16545 168 SUPERFAMILY SSF46689 5 75 3.91E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19825 147baf3e14c6c431e87b2e31d8d16545 168 Gene3D G3DSA:1.10.357.10 2 166 1.4E-43 T 12-10-2018 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 Gene3D G3DSA:1.10.260.40 3 64 3.1E-18 T 12-10-2018 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 54 3.8E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 Gene3D G3DSA:3.40.50.2300 67 316 3.2E-69 T 12-10-2018 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 Gene3D G3DSA:3.40.50.2300 172 301 3.2E-69 T 12-10-2018 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 10 28 - T 12-10-2018 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 SUPERFAMILY SSF47413 8 65 3.54E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 SMART SM00354 7 77 1.9E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 Pfam PF13377 Periplasmic binding protein-like domain 181 338 1.2E-32 T 12-10-2018 AFR_18305 2ccd48a5c610780c3a384a8fcdcb83f8 344 SUPERFAMILY SSF53822 67 341 3.87E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_35800 b9fd21d10ade28d7ae6cbc309f83b579 153 Gene3D G3DSA:3.90.950.20 1 153 4.7E-57 T 12-10-2018 IPR036653 CinA-like, C-terminal AFR_35800 b9fd21d10ade28d7ae6cbc309f83b579 153 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 8 152 5.0E-35 T 12-10-2018 IPR008136 CinA, C-terminal AFR_35800 b9fd21d10ade28d7ae6cbc309f83b579 153 SUPERFAMILY SSF142433 3 151 1.83E-48 T 12-10-2018 IPR036653 CinA-like, C-terminal AFR_35800 b9fd21d10ade28d7ae6cbc309f83b579 153 Pfam PF02464 Competence-damaged protein 3 151 1.7E-51 T 12-10-2018 IPR008136 CinA, C-terminal AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 257 418 1.9E-32 T 12-10-2018 IPR000160 GGDEF domain AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 Gene3D G3DSA:3.20.20.450 434 694 2.0E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 SUPERFAMILY SSF55073 265 419 1.49E-37 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 Pfam PF00563 EAL domain 453 679 1.0E-68 T 12-10-2018 IPR001633 EAL domain AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 Gene3D G3DSA:3.30.70.270 262 431 3.2E-46 T 12-10-2018 AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 Pfam PF00990 Diguanylate cyclase, GGDEF domain 261 417 3.1E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 SUPERFAMILY SSF141868 454 693 7.06E-80 T 12-10-2018 IPR035919 EAL domain superfamily AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 SMART SM00052 431 684 2.9E-99 T 12-10-2018 IPR001633 EAL domain AFR_36985 e64c4ca56129d62d675cda784fcbf8f8 709 SMART SM00267 249 422 1.4E-47 T 12-10-2018 IPR000160 GGDEF domain AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 66 5.4E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 Gene3D G3DSA:1.10.10.10 7 76 2.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 SUPERFAMILY SSF53383 90 467 4.68E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 Gene3D G3DSA:3.90.1150.10 102 465 1.4E-81 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 3.7E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 3.7E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 SUPERFAMILY SSF46785 16 74 3.1E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 SMART SM00345 9 66 4.6E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 Gene3D G3DSA:3.40.640.10 138 359 1.4E-81 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_23835 15f33b2d18707df743963e524a3b9fb2 472 Pfam PF00155 Aminotransferase class I and II 104 413 7.3E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_39950 38e6ce4dcb3fffaf03b7126ac61fb191 260 Pfam PF13359 DDE superfamily endonuclease 102 251 3.3E-30 T 12-10-2018 IPR027806 Harbinger transposase-derived nuclease domain AFR_39950 38e6ce4dcb3fffaf03b7126ac61fb191 260 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 85 7.5E-15 T 12-10-2018 IPR027805 Transposase, Helix-turn-helix domain AFR_32755 292f67c8dcd05a28046d694fa7ff272d 303 Gene3D G3DSA:3.40.190.10 96 196 1.6E-63 T 12-10-2018 AFR_32755 292f67c8dcd05a28046d694fa7ff272d 303 Gene3D G3DSA:1.10.8.450 230 263 1.6E-63 T 12-10-2018 AFR_32755 292f67c8dcd05a28046d694fa7ff272d 303 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 27 298 3.2E-53 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 AFR_32755 292f67c8dcd05a28046d694fa7ff272d 303 Gene3D G3DSA:3.40.190.10 27 296 1.6E-63 T 12-10-2018 AFR_32755 292f67c8dcd05a28046d694fa7ff272d 303 SUPERFAMILY SSF53850 20 243 1.17E-40 T 12-10-2018 AFR_32755 292f67c8dcd05a28046d694fa7ff272d 303 Pfam PF09084 NMT1/THI5 like 39 239 9.7E-24 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_07645 7370e3ecd0e064f2e6acb75a9d42b278 263 Gene3D G3DSA:3.40.50.1820 1 263 2.0E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_07645 7370e3ecd0e064f2e6acb75a9d42b278 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 1.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_07645 7370e3ecd0e064f2e6acb75a9d42b278 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_07645 7370e3ecd0e064f2e6acb75a9d42b278 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_07645 7370e3ecd0e064f2e6acb75a9d42b278 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 43 58 1.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_07645 7370e3ecd0e064f2e6acb75a9d42b278 263 SUPERFAMILY SSF53474 6 263 1.1E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_07645 7370e3ecd0e064f2e6acb75a9d42b278 263 Pfam PF12697 Alpha/beta hydrolase family 21 258 2.4E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15655 b079d9be909aeb3ae78f9a7f943ced46 289 PIRSF PIRSF000103 1 289 7.3E-71 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFR_15655 b079d9be909aeb3ae78f9a7f943ced46 289 Gene3D G3DSA:3.40.50.720 1 160 2.8E-47 T 12-10-2018 AFR_15655 b079d9be909aeb3ae78f9a7f943ced46 289 SUPERFAMILY SSF48179 161 285 2.49E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_15655 b079d9be909aeb3ae78f9a7f943ced46 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 154 2.8E-42 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_15655 b079d9be909aeb3ae78f9a7f943ced46 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 282 2.7E-38 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFR_15655 b079d9be909aeb3ae78f9a7f943ced46 289 SUPERFAMILY SSF51735 4 155 3.09E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15655 b079d9be909aeb3ae78f9a7f943ced46 289 Gene3D G3DSA:1.10.1040.10 161 288 8.7E-35 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_35080 cc6f1476e1f53cc555094c52fdb6e8a2 224 Pfam PF00005 ABC transporter 22 170 8.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_35080 cc6f1476e1f53cc555094c52fdb6e8a2 224 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_35080 cc6f1476e1f53cc555094c52fdb6e8a2 224 Gene3D G3DSA:3.40.50.300 3 224 3.9E-68 T 12-10-2018 AFR_35080 cc6f1476e1f53cc555094c52fdb6e8a2 224 SUPERFAMILY SSF52540 5 222 1.73E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35080 cc6f1476e1f53cc555094c52fdb6e8a2 224 SMART SM00382 31 219 1.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_34595 524389e109adbd2c24d7c9385fa6ba8e 169 Pfam PF12680 SnoaL-like domain 7 102 3.3E-9 T 12-10-2018 IPR037401 SnoaL-like domain AFR_34595 524389e109adbd2c24d7c9385fa6ba8e 169 Gene3D G3DSA:3.10.450.50 2 129 9.6E-29 T 12-10-2018 AFR_34595 524389e109adbd2c24d7c9385fa6ba8e 169 SUPERFAMILY SSF54427 4 120 3.09E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_37350 df9ebc7401d0450f27cf6b0633469187 272 PRINTS PR00125 ATP synthase delta subunit signature 245 263 6.9E-8 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37350 df9ebc7401d0450f27cf6b0633469187 272 PRINTS PR00125 ATP synthase delta subunit signature 230 245 6.9E-8 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37350 df9ebc7401d0450f27cf6b0633469187 272 Pfam PF00213 ATP synthase delta (OSCP) subunit 109 268 3.8E-28 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37350 df9ebc7401d0450f27cf6b0633469187 272 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 110 266 4.0E-18 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37350 df9ebc7401d0450f27cf6b0633469187 272 Hamap MF_01416 ATP synthase subunit delta [atpD]. 96 272 13.266 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 SUPERFAMILY SSF46894 10 87 2.75E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 SUPERFAMILY SSF48452 828 923 3.21E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 SUPERFAMILY SSF52540 287 514 5.32E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 Pfam PF13191 AAA ATPase domain 288 441 4.4E-22 T 12-10-2018 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 102 1.8E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 Gene3D G3DSA:1.10.10.10 2 106 1.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 SMART SM01043 110 253 1.4E-44 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 Gene3D G3DSA:1.25.40.10 108 281 6.8E-47 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 SUPERFAMILY SSF48452 731 875 4.86E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 SUPERFAMILY SSF48452 105 275 1.54E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 SMART SM00862 23 103 2.6E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_02575 ba131ef44312a313427e7065b1ef4d69 1152 Pfam PF03704 Bacterial transcriptional activator domain 110 253 9.5E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_03910 b28737c0c8e90c1a61b23558e9b3b793 190 SUPERFAMILY SSF48498 77 188 4.0E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_03910 b28737c0c8e90c1a61b23558e9b3b793 190 Gene3D G3DSA:1.10.357.10 53 190 1.5E-21 T 12-10-2018 AFR_03910 b28737c0c8e90c1a61b23558e9b3b793 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 73 182 6.4E-19 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_03910 b28737c0c8e90c1a61b23558e9b3b793 190 SUPERFAMILY SSF46689 3 65 1.49E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03910 b28737c0c8e90c1a61b23558e9b3b793 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03910 b28737c0c8e90c1a61b23558e9b3b793 190 Gene3D G3DSA:1.10.10.60 1 51 4.2E-13 T 12-10-2018 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Pfam PF16450 Proteasomal ATPase OB/ID domain 58 193 7.7E-51 T 12-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 ProSitePatterns PS00674 AAA-protein family signature. 354 372 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Gene3D G3DSA:2.40.50.140 115 194 4.0E-21 T 12-10-2018 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Gene3D G3DSA:1.20.5.170 4 54 3.2E-15 T 12-10-2018 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 SMART SM00382 232 386 1.4E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Gene3D G3DSA:2.40.50.140 55 114 1.2E-28 T 12-10-2018 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 SUPERFAMILY SSF52540 194 410 2.94E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 16 533 49.954 T 12-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Gene3D G3DSA:3.40.50.300 195 384 9.4E-63 T 12-10-2018 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Gene3D G3DSA:1.10.8.60 385 435 9.4E-63 T 12-10-2018 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 236 384 1.5E-48 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_26420 a7b86168011db2f7cc9440e5598b1ca1 555 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 14 532 4.2E-250 T 12-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 AFR_36055 e9dfc1731f6f1a69398e159d57e7c47c 448 Pfam PF00120 Glutamine synthetase, catalytic domain 114 443 7.9E-95 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_36055 e9dfc1731f6f1a69398e159d57e7c47c 448 Gene3D G3DSA:3.30.590.10 116 447 1.7E-92 T 12-10-2018 AFR_36055 e9dfc1731f6f1a69398e159d57e7c47c 448 SUPERFAMILY SSF55931 115 446 5.2E-95 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_36055 e9dfc1731f6f1a69398e159d57e7c47c 448 SMART SM01230 113 365 6.2E-93 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_36055 e9dfc1731f6f1a69398e159d57e7c47c 448 SUPERFAMILY SSF54368 9 111 6.67E-16 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_36055 e9dfc1731f6f1a69398e159d57e7c47c 448 Gene3D G3DSA:3.10.20.70 3 114 3.1E-6 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 Pfam PF00206 Lyase 98 302 1.5E-39 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 SUPERFAMILY SSF48557 37 410 1.56E-86 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 Gene3D G3DSA:1.10.40.30 364 403 2.3E-106 T 12-10-2018 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 1.9E-20 T 12-10-2018 IPR000362 Fumarate lyase family AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 1.9E-20 T 12-10-2018 IPR000362 Fumarate lyase family AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 1.9E-20 T 12-10-2018 IPR000362 Fumarate lyase family AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 1.9E-20 T 12-10-2018 IPR000362 Fumarate lyase family AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 TIGRFAM TIGR00838 argH: argininosuccinate lyase 38 404 3.0E-84 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 Gene3D G3DSA:1.10.275.10 38 231 2.3E-106 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 Pfam PF14698 Argininosuccinate lyase C-terminal 366 403 3.2E-11 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 4.0E-30 T 12-10-2018 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 4.0E-30 T 12-10-2018 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 4.0E-30 T 12-10-2018 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 4.0E-30 T 12-10-2018 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 4.0E-30 T 12-10-2018 AFR_18480 99a2cc4a03fc32c5439d6def80f7a85c 480 Gene3D G3DSA:1.20.200.10 121 362 2.3E-106 T 12-10-2018 AFR_02625 9344c51695ead15414d3a34f85198754 495 Gene3D G3DSA:1.20.1250.20 248 449 2.0E-14 T 12-10-2018 AFR_02625 9344c51695ead15414d3a34f85198754 495 SUPERFAMILY SSF103473 2 451 8.63E-66 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_02625 9344c51695ead15414d3a34f85198754 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 400 5.1E-82 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_02625 9344c51695ead15414d3a34f85198754 495 Pfam PF07690 Major Facilitator Superfamily 6 398 3.2E-50 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_02625 9344c51695ead15414d3a34f85198754 495 Gene3D G3DSA:1.20.1720.10 1 209 1.0E-55 T 12-10-2018 AFR_02625 9344c51695ead15414d3a34f85198754 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 4 28 5.3E-5 T 12-10-2018 AFR_02625 9344c51695ead15414d3a34f85198754 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 290 314 5.3E-5 T 12-10-2018 AFR_02625 9344c51695ead15414d3a34f85198754 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 115 5.3E-5 T 12-10-2018 AFR_02625 9344c51695ead15414d3a34f85198754 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 149 5.3E-5 T 12-10-2018 AFR_24580 fa239edbff854773affea853d9ff07bf 559 SUPERFAMILY SSF52540 80 369 5.03E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24580 fa239edbff854773affea853d9ff07bf 559 Gene3D G3DSA:3.40.50.300 2 217 8.1E-79 T 12-10-2018 AFR_24580 fa239edbff854773affea853d9ff07bf 559 Pfam PF00270 DEAD/DEAH box helicase 35 198 1.1E-51 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_24580 fa239edbff854773affea853d9ff07bf 559 Pfam PF03880 DbpA RNA binding domain 483 553 1.2E-24 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain AFR_24580 fa239edbff854773affea853d9ff07bf 559 Pfam PF00271 Helicase conserved C-terminal domain 247 348 1.7E-27 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_24580 fa239edbff854773affea853d9ff07bf 559 Gene3D G3DSA:3.40.50.300 228 448 1.2E-48 T 12-10-2018 AFR_24580 fa239edbff854773affea853d9ff07bf 559 SMART SM00490 267 348 3.8E-31 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_24580 fa239edbff854773affea853d9ff07bf 559 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 159 167 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFR_24580 fa239edbff854773affea853d9ff07bf 559 Gene3D G3DSA:3.30.70.330 482 556 1.0E-20 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFR_24580 fa239edbff854773affea853d9ff07bf 559 SMART SM00487 30 228 1.0E-66 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_20320 325111c8014549cc66691e80748c975a 453 SMART SM00388 236 301 5.4E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_20320 325111c8014549cc66691e80748c975a 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 300 6.6E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_20320 325111c8014549cc66691e80748c975a 453 SUPERFAMILY SSF47384 219 300 1.79E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_20320 325111c8014549cc66691e80748c975a 453 SMART SM00387 342 453 9.1E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_20320 325111c8014549cc66691e80748c975a 453 SMART SM00304 182 235 3.5E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_20320 325111c8014549cc66691e80748c975a 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20320 325111c8014549cc66691e80748c975a 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20320 325111c8014549cc66691e80748c975a 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20320 325111c8014549cc66691e80748c975a 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20320 325111c8014549cc66691e80748c975a 453 SUPERFAMILY SSF55874 291 451 2.62E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20320 325111c8014549cc66691e80748c975a 453 Pfam PF00672 HAMP domain 184 231 2.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_20320 325111c8014549cc66691e80748c975a 453 SUPERFAMILY SSF158472 185 231 4.58E-6 T 12-10-2018 AFR_20320 325111c8014549cc66691e80748c975a 453 Gene3D G3DSA:1.10.287.130 186 303 2.0E-27 T 12-10-2018 AFR_20320 325111c8014549cc66691e80748c975a 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 450 3.6E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_20320 325111c8014549cc66691e80748c975a 453 Gene3D G3DSA:3.30.565.10 311 452 6.4E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24420 47aecf18fb5fa38125ae333032b28e7b 343 Gene3D G3DSA:3.40.190.10 116 213 2.9E-53 T 12-10-2018 AFR_24420 47aecf18fb5fa38125ae333032b28e7b 343 SMART SM00062 35 244 0.0021 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_24420 47aecf18fb5fa38125ae333032b28e7b 343 Gene3D G3DSA:1.10.8.450 249 280 2.9E-53 T 12-10-2018 AFR_24420 47aecf18fb5fa38125ae333032b28e7b 343 SUPERFAMILY SSF53850 34 258 6.08E-36 T 12-10-2018 AFR_24420 47aecf18fb5fa38125ae333032b28e7b 343 Gene3D G3DSA:3.40.190.10 36 248 2.9E-53 T 12-10-2018 AFR_24420 47aecf18fb5fa38125ae333032b28e7b 343 Pfam PF09084 NMT1/THI5 like 119 258 7.4E-13 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_02975 c0db5dbd8d8ca076f5f534e46fbcee47 143 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 45 61 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain AFR_02975 c0db5dbd8d8ca076f5f534e46fbcee47 143 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 2 136 3.4E-28 T 12-10-2018 IPR002178 PTS EIIA type-2 domain AFR_02975 c0db5dbd8d8ca076f5f534e46fbcee47 143 Gene3D G3DSA:3.40.930.10 1 138 3.1E-27 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFR_02975 c0db5dbd8d8ca076f5f534e46fbcee47 143 SUPERFAMILY SSF55804 3 137 6.41E-32 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 Pfam PF00875 DNA photolyase 4 163 2.2E-46 T 12-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 PRINTS PR00147 DNA photolyase signature 363 377 3.7E-25 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 PRINTS PR00147 DNA photolyase signature 304 320 3.7E-25 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 PRINTS PR00147 DNA photolyase signature 324 342 3.7E-25 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 PRINTS PR00147 DNA photolyase signature 138 154 3.7E-25 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 SUPERFAMILY SSF48173 189 436 3.27E-90 T 12-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 304 316 - T 12-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 SUPERFAMILY SSF52425 3 183 2.49E-44 T 12-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 Gene3D G3DSA:1.25.40.80 126 269 9.8E-70 T 12-10-2018 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 Gene3D G3DSA:3.40.50.620 5 193 9.8E-70 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 324 343 - T 12-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 Pfam PF03441 FAD binding domain of DNA photolyase 256 435 9.8E-70 T 12-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 AFR_00900 19f6860ca626aeddeffd4b7c953b7de8 444 Gene3D G3DSA:1.10.579.10 275 441 4.5E-67 T 12-10-2018 AFR_22800 bedef86324291f700c693cfe560e2889 312 Pfam PF00561 alpha/beta hydrolase fold 4 293 8.3E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_22800 bedef86324291f700c693cfe560e2889 312 PRINTS PR00412 Epoxide hydrolase signature 28 43 6.2E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_22800 bedef86324291f700c693cfe560e2889 312 PRINTS PR00412 Epoxide hydrolase signature 88 101 6.2E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_22800 bedef86324291f700c693cfe560e2889 312 PRINTS PR00412 Epoxide hydrolase signature 74 87 6.2E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_22800 bedef86324291f700c693cfe560e2889 312 PRINTS PR00412 Epoxide hydrolase signature 282 304 6.2E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_22800 bedef86324291f700c693cfe560e2889 312 PRINTS PR00412 Epoxide hydrolase signature 8 26 6.2E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_22800 bedef86324291f700c693cfe560e2889 312 Gene3D G3DSA:3.40.50.1820 2 307 1.2E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22800 bedef86324291f700c693cfe560e2889 312 SUPERFAMILY SSF53474 4 306 1.53E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_26500 cdc0c516a5a94f73182e99e4e7b19a5b 149 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 148 1.0E-20 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_26500 cdc0c516a5a94f73182e99e4e7b19a5b 149 SUPERFAMILY SSF55961 1 149 1.53E-33 T 12-10-2018 AFR_26500 cdc0c516a5a94f73182e99e4e7b19a5b 149 Gene3D G3DSA:3.30.530.20 1 149 3.2E-37 T 12-10-2018 IPR023393 START-like domain superfamily AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 Gene3D G3DSA:3.40.50.150 12 315 1.8E-88 T 12-10-2018 AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 12 319 34.672 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 Pfam PF01795 MraW methylase family 11 319 1.3E-101 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 11 318 1.8E-84 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 SUPERFAMILY SSF81799 123 224 3.01E-31 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 PIRSF PIRSF004486 7 320 3.2E-92 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 Gene3D G3DSA:1.10.150.170 121 226 1.8E-88 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 AFR_09975 309e3dd8d4a0b7cb54c11b0511a7b1e9 321 SUPERFAMILY SSF53335 12 319 1.54E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 171 8.4E-44 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 525 1.4E-28 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 SUPERFAMILY SSF52467 158 337 2.62E-32 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 Gene3D G3DSA:3.40.50.1220 185 336 4.0E-35 T 12-10-2018 AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 Gene3D G3DSA:3.40.50.970 337 538 2.2E-51 T 12-10-2018 AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 317 2.5E-22 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 Gene3D G3DSA:3.40.50.970 1 177 1.2E-49 T 12-10-2018 AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 SUPERFAMILY SSF52518 354 534 5.9E-48 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_37050 6a9f12857750e25efbd488e1fcfc1ae4 540 SUPERFAMILY SSF52518 6 186 5.47E-41 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_04105 395b214535b73d575e95eb91c0643681 604 Gene3D G3DSA:3.40.50.300 247 412 5.7E-48 T 12-10-2018 AFR_04105 395b214535b73d575e95eb91c0643681 604 Gene3D G3DSA:3.40.50.300 10 235 7.8E-71 T 12-10-2018 AFR_04105 395b214535b73d575e95eb91c0643681 604 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 178 186 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFR_04105 395b214535b73d575e95eb91c0643681 604 SUPERFAMILY SSF52540 99 384 1.58E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04105 395b214535b73d575e95eb91c0643681 604 SMART SM00490 285 366 7.0E-35 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_04105 395b214535b73d575e95eb91c0643681 604 SMART SM00487 46 249 6.7E-53 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_04105 395b214535b73d575e95eb91c0643681 604 Pfam PF00270 DEAD/DEAH box helicase 52 217 2.0E-46 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_04105 395b214535b73d575e95eb91c0643681 604 Pfam PF00271 Helicase conserved C-terminal domain 258 366 4.5E-30 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_42205 c33c2caaa4d96915fbb66e2b2e85ec4d 237 Pfam PF13489 Methyltransferase domain 39 173 2.7E-11 T 12-10-2018 AFR_42205 c33c2caaa4d96915fbb66e2b2e85ec4d 237 Gene3D G3DSA:3.40.50.150 24 189 7.3E-27 T 12-10-2018 AFR_42205 c33c2caaa4d96915fbb66e2b2e85ec4d 237 SUPERFAMILY SSF53335 25 185 2.63E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_36240 474b34805def04012c2100d0dca59c96 391 Gene3D G3DSA:3.40.50.450 3 316 1.0E-85 T 12-10-2018 AFR_36240 474b34805def04012c2100d0dca59c96 391 SUPERFAMILY SSF102405 119 320 5.19E-32 T 12-10-2018 AFR_36240 474b34805def04012c2100d0dca59c96 391 SUPERFAMILY SSF46785 333 387 2.77E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_36240 474b34805def04012c2100d0dca59c96 391 Pfam PF02481 DNA recombination-mediator protein A 81 297 1.8E-66 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFR_36240 474b34805def04012c2100d0dca59c96 391 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 81 296 3.5E-58 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFR_22415 73f91114e09717719aeed98947d8945b 255 Gene3D G3DSA:3.20.20.70 3 245 2.1E-48 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_22415 73f91114e09717719aeed98947d8945b 255 SMART SM01130 6 255 8.0E-34 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_22415 73f91114e09717719aeed98947d8945b 255 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 2.2E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_22415 73f91114e09717719aeed98947d8945b 255 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 2.2E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_22415 73f91114e09717719aeed98947d8945b 255 PIRSF PIRSF001365 4 252 3.1E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_22415 73f91114e09717719aeed98947d8945b 255 SUPERFAMILY SSF51569 2 244 9.0E-45 T 12-10-2018 AFR_22415 73f91114e09717719aeed98947d8945b 255 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 43 60 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFR_22415 73f91114e09717719aeed98947d8945b 255 Pfam PF00701 Dihydrodipicolinate synthetase family 11 210 6.2E-24 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SUPERFAMILY SSF52113 633 707 6.71E-18 T 12-10-2018 IPR036420 BRCT domain superfamily AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SMART SM00278 551 570 1900.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SMART SM00278 587 606 0.058 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SMART SM00278 479 498 640.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SMART SM00292 635 712 2.7E-11 T 12-10-2018 IPR001357 BRCT domain AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 635 704 1.3E-11 T 12-10-2018 IPR001357 BRCT domain AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 PIRSF PIRSF001604 32 713 2.1E-238 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 148 177 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Gene3D G3DSA:1.10.287.610 29 102 1.9E-27 T 12-10-2018 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 38 350 1.3E-125 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 363 378 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SUPERFAMILY SSF56091 38 350 1.15E-114 T 12-10-2018 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 46 704 1.0E-238 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SUPERFAMILY SSF50249 349 433 1.15E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Gene3D G3DSA:1.10.150.20 465 543 2.4E-12 T 12-10-2018 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Gene3D G3DSA:2.20.70.80 423 462 8.2E-6 T 12-10-2018 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Gene3D G3DSA:3.30.470.90 103 349 5.9E-103 T 12-10-2018 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SUPERFAMILY SSF47781 435 626 2.67E-50 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Gene3D G3DSA:3.40.50.10190 632 717 3.1E-22 T 12-10-2018 IPR036420 BRCT domain superfamily AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Hamap MF_01588 DNA ligase [ligA]. 37 709 51.285 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Pfam PF12826 Helix-hairpin-helix motif 549 616 3.5E-18 T 12-10-2018 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 353 430 4.4E-31 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Gene3D G3DSA:2.40.50.140 350 421 9.7E-28 T 12-10-2018 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 SMART SM00532 38 481 2.2E-263 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 AFR_36995 1a050182f94d642b7891ff9ed8b711f4 744 Gene3D G3DSA:1.10.150.20 544 628 6.6E-27 T 12-10-2018 AFR_38125 d5085b6ba70e8c5d6b2537f8b71b6719 200 Gene3D G3DSA:3.40.50.1820 26 195 2.9E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_38125 d5085b6ba70e8c5d6b2537f8b71b6719 200 SUPERFAMILY SSF53474 3 193 1.92E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_42120 b13388d076ea72a0f94afa0812a3e951 368 SUPERFAMILY SSF50998 233 364 1.88E-11 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_42120 b13388d076ea72a0f94afa0812a3e951 368 SUPERFAMILY SSF50998 5 262 1.96E-22 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_42120 b13388d076ea72a0f94afa0812a3e951 368 Pfam PF13360 PQQ-like domain 171 366 9.1E-13 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_42120 b13388d076ea72a0f94afa0812a3e951 368 Gene3D G3DSA:2.140.10.10 3 192 2.0E-16 T 12-10-2018 AFR_42120 b13388d076ea72a0f94afa0812a3e951 368 Gene3D G3DSA:2.130.10.10 193 368 6.1E-17 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_05445 b3193c2730cddac95675dbaac7ca662a 477 SUPERFAMILY SSF55073 318 462 4.71E-42 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_05445 b3193c2730cddac95675dbaac7ca662a 477 Gene3D G3DSA:3.30.70.270 300 462 2.2E-47 T 12-10-2018 AFR_05445 b3193c2730cddac95675dbaac7ca662a 477 SMART SM00267 302 463 3.9E-49 T 12-10-2018 IPR000160 GGDEF domain AFR_05445 b3193c2730cddac95675dbaac7ca662a 477 Pfam PF00990 Diguanylate cyclase, GGDEF domain 315 459 4.3E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_05445 b3193c2730cddac95675dbaac7ca662a 477 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 312 461 9.2E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_05310 f1a8fa27adbd0bc897cd01fcb99d6f33 352 PIRSF PIRSF038925 2 352 4.5E-84 T 12-10-2018 IPR026287 Adenosine monophosphate-protein transferase AFR_05310 f1a8fa27adbd0bc897cd01fcb99d6f33 352 Pfam PF02661 Fic/DOC family 97 204 2.3E-17 T 12-10-2018 IPR003812 Fido domain AFR_05310 f1a8fa27adbd0bc897cd01fcb99d6f33 352 Pfam PF13784 Fic/DOC family N-terminal 13 91 5.2E-20 T 12-10-2018 IPR025758 Fic/DOC N-terminal AFR_05310 f1a8fa27adbd0bc897cd01fcb99d6f33 352 SUPERFAMILY SSF140931 77 271 8.37E-35 T 12-10-2018 IPR036597 Fido-like domain superfamily AFR_05310 f1a8fa27adbd0bc897cd01fcb99d6f33 352 Gene3D G3DSA:1.10.3290.10 35 272 1.7E-42 T 12-10-2018 IPR036597 Fido-like domain superfamily AFR_03505 b62de3055a6a1e694da081003702dd7c 739 Gene3D G3DSA:3.20.20.30 7 274 9.4E-57 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 SUPERFAMILY SSF51679 5 275 4.71E-59 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 Gene3D G3DSA:3.40.462.20 503 695 7.5E-79 T 12-10-2018 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 Gene3D G3DSA:3.30.43.10 313 389 2.4E-16 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 Pfam PF08031 Berberine and berberine like 704 734 2.5E-5 T 12-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 Gene3D G3DSA:3.30.465.10 403 723 7.5E-79 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 Pfam PF00296 Luciferase-like monooxygenase 8 231 3.3E-48 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 Pfam PF01565 FAD binding domain 335 472 1.5E-29 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_03505 b62de3055a6a1e694da081003702dd7c 739 SUPERFAMILY SSF56176 318 500 4.09E-51 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_26365 6df44423a5c4dc3779553c85d348b97a 331 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 25 315 2.0E-50 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_26365 6df44423a5c4dc3779553c85d348b97a 331 SUPERFAMILY SSF161111 24 236 9.94E-35 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_26365 6df44423a5c4dc3779553c85d348b97a 331 SUPERFAMILY SSF160240 239 313 5.49E-9 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFR_26365 6df44423a5c4dc3779553c85d348b97a 331 Gene3D G3DSA:1.20.1510.10 23 235 6.9E-31 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_26365 6df44423a5c4dc3779553c85d348b97a 331 Pfam PF01545 Cation efflux family 26 235 9.5E-32 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_19950 e8734954287c33d7570c56b78020ffaf 227 SUPERFAMILY SSF46785 170 217 3.0E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19950 e8734954287c33d7570c56b78020ffaf 227 PIRSF PIRSF006171 2 227 1.0E-68 T 12-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 AFR_19950 e8734954287c33d7570c56b78020ffaf 227 SUPERFAMILY SSF52172 3 180 3.56E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_19950 e8734954287c33d7570c56b78020ffaf 227 Pfam PF00072 Response regulator receiver domain 6 117 3.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19950 e8734954287c33d7570c56b78020ffaf 227 SMART SM00448 4 117 1.1E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19950 e8734954287c33d7570c56b78020ffaf 227 Gene3D G3DSA:1.10.10.10 160 217 8.2E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19950 e8734954287c33d7570c56b78020ffaf 227 Gene3D G3DSA:3.40.50.2300 1 145 1.7E-30 T 12-10-2018 AFR_36200 5903d54abb2cf2aeee49227135068c27 387 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 341 367 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 AFR_36200 5903d54abb2cf2aeee49227135068c27 387 Pfam PF01148 Cytidylyltransferase family 129 382 1.0E-55 T 12-10-2018 AFR_22350 24c2dd924b99e2f4fb84f328ccdf2254 435 Gene3D G3DSA:3.20.20.30 2 435 5.5E-125 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22350 24c2dd924b99e2f4fb84f328ccdf2254 435 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 15 431 2.5E-124 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFR_22350 24c2dd924b99e2f4fb84f328ccdf2254 435 Pfam PF00296 Luciferase-like monooxygenase 25 385 2.3E-56 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_22350 24c2dd924b99e2f4fb84f328ccdf2254 435 SUPERFAMILY SSF51679 3 434 2.49E-105 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22350 24c2dd924b99e2f4fb84f328ccdf2254 435 PIRSF PIRSF000337 1 435 2.4E-141 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFR_08655 69024da244b34743d56fbb7270478533 212 Pfam PF00484 Carbonic anhydrase 61 208 1.0E-32 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_08655 69024da244b34743d56fbb7270478533 212 SMART SM00947 54 212 1.1E-33 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_08655 69024da244b34743d56fbb7270478533 212 Gene3D G3DSA:3.40.1050.10 12 212 5.0E-54 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_08655 69024da244b34743d56fbb7270478533 212 SUPERFAMILY SSF53056 17 211 2.75E-42 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 SUPERFAMILY SSF47413 2 58 5.49E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 Gene3D G3DSA:1.10.260.40 1 59 2.6E-22 T 12-10-2018 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 12-10-2018 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 SUPERFAMILY SSF53822 78 317 4.32E-51 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 1.8E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 Gene3D G3DSA:3.40.50.2300 167 294 2.5E-61 T 12-10-2018 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 Gene3D G3DSA:3.40.50.2300 80 316 2.5E-61 T 12-10-2018 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 SMART SM00354 3 73 8.7E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_36930 c9d19e0e10e8b0590bd1a0defd020386 339 Pfam PF13377 Periplasmic binding protein-like domain 175 333 1.3E-33 T 12-10-2018 AFR_33115 b2b665707dd8ee8023cf4c380875bf31 260 Gene3D G3DSA:1.10.260.40 1 45 1.6E-6 T 12-10-2018 AFR_33115 b2b665707dd8ee8023cf4c380875bf31 260 Pfam PF13560 Helix-turn-helix domain 2 40 1.2E-8 T 12-10-2018 AFR_33115 b2b665707dd8ee8023cf4c380875bf31 260 SUPERFAMILY SSF47413 2 35 5.04E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_40145 7389f6bce7c785b4a59ea9a3cbe6566c 780 Gene3D G3DSA:3.40.50.300 109 249 5.2E-11 T 12-10-2018 AFR_40145 7389f6bce7c785b4a59ea9a3cbe6566c 780 Gene3D G3DSA:1.25.40.10 508 761 1.0E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_40145 7389f6bce7c785b4a59ea9a3cbe6566c 780 SUPERFAMILY SSF52540 111 360 2.21E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40145 7389f6bce7c785b4a59ea9a3cbe6566c 780 Gene3D G3DSA:3.30.70.1230 1 108 4.5E-13 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_40145 7389f6bce7c785b4a59ea9a3cbe6566c 780 SUPERFAMILY SSF55073 1 101 1.18E-10 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_25665 1f976fd7ba7f0e740028f3f00e17479d 157 SUPERFAMILY SSF50341 13 146 3.53E-17 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_25665 1f976fd7ba7f0e740028f3f00e17479d 157 Pfam PF01584 CheW-like domain 14 142 7.7E-13 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_25665 1f976fd7ba7f0e740028f3f00e17479d 157 SMART SM00260 8 142 3.7E-5 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_25665 1f976fd7ba7f0e740028f3f00e17479d 157 Gene3D G3DSA:2.30.30.40 15 136 8.8E-10 T 12-10-2018 AFR_25665 1f976fd7ba7f0e740028f3f00e17479d 157 Gene3D G3DSA:2.40.50.180 31 94 8.8E-10 T 12-10-2018 AFR_21955 62191bf3a9f04d9ef2b742474ddb121f 234 SUPERFAMILY SSF102198 3 225 6.54E-40 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_21955 62191bf3a9f04d9ef2b742474ddb121f 234 Gene3D G3DSA:3.50.30.50 1 232 7.1E-56 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_21955 62191bf3a9f04d9ef2b742474ddb121f 234 Pfam PF04199 Putative cyclase 5 173 3.3E-29 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_41975 67adaf342876d61ba2b2fed21fec6e06 679 SUPERFAMILY SSF117892 57 202 3.53E-10 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily AFR_41975 67adaf342876d61ba2b2fed21fec6e06 679 Pfam PF01145 SPFH domain / Band 7 family 32 176 1.8E-6 T 12-10-2018 IPR001107 Band 7 domain AFR_41975 67adaf342876d61ba2b2fed21fec6e06 679 Gene3D G3DSA:3.30.479.30 66 182 7.2E-9 T 12-10-2018 AFR_31270 d207da2953a709adc6122efdadc28531 548 SUPERFAMILY SSF52540 63 352 3.25E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31270 d207da2953a709adc6122efdadc28531 548 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 13 350 4.1E-98 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 AFR_31270 d207da2953a709adc6122efdadc28531 548 SMART SM00487 19 218 5.2E-28 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_31270 d207da2953a709adc6122efdadc28531 548 Pfam PF00271 Helicase conserved C-terminal domain 228 332 1.4E-16 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_31270 d207da2953a709adc6122efdadc28531 548 Pfam PF00270 DEAD/DEAH box helicase 27 188 8.8E-14 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_31270 d207da2953a709adc6122efdadc28531 548 SMART SM00490 252 333 2.0E-24 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_31270 d207da2953a709adc6122efdadc28531 548 Gene3D G3DSA:3.40.50.300 5 208 2.4E-65 T 12-10-2018 AFR_31270 d207da2953a709adc6122efdadc28531 548 Pfam PF16124 RecQ zinc-binding 433 479 7.0E-11 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain AFR_11070 91303b863b2c8d17047a62810c93f4e3 164 PRINTS PR00502 NUDIX hydrolase family signature 50 64 1.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_11070 91303b863b2c8d17047a62810c93f4e3 164 PRINTS PR00502 NUDIX hydrolase family signature 64 79 1.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_11070 91303b863b2c8d17047a62810c93f4e3 164 Pfam PF00293 NUDIX domain 30 137 5.2E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_11070 91303b863b2c8d17047a62810c93f4e3 164 Gene3D G3DSA:3.90.79.10 6 141 1.8E-28 T 12-10-2018 AFR_11070 91303b863b2c8d17047a62810c93f4e3 164 ProSitePatterns PS00893 Nudix box signature. 55 76 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_11070 91303b863b2c8d17047a62810c93f4e3 164 SUPERFAMILY SSF55811 23 139 1.49E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_05340 b3543643baf0608f65ee209a4c9b582a 168 Pfam PF00583 Acetyltransferase (GNAT) family 39 121 1.3E-12 T 12-10-2018 IPR000182 GNAT domain AFR_05340 b3543643baf0608f65ee209a4c9b582a 168 SUPERFAMILY SSF55729 1 133 1.38E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05340 b3543643baf0608f65ee209a4c9b582a 168 Gene3D G3DSA:3.40.630.30 3 144 2.4E-30 T 12-10-2018 AFR_15755 f50c847f669b4c8cd98677cecc05fdc7 475 Pfam PF00171 Aldehyde dehydrogenase family 13 470 8.4E-150 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_15755 f50c847f669b4c8cd98677cecc05fdc7 475 Gene3D G3DSA:3.40.309.10 256 443 3.2E-157 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_15755 f50c847f669b4c8cd98677cecc05fdc7 475 SUPERFAMILY SSF53720 3 473 2.09E-149 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_15755 f50c847f669b4c8cd98677cecc05fdc7 475 Gene3D G3DSA:3.40.605.10 18 466 3.2E-157 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_15755 f50c847f669b4c8cd98677cecc05fdc7 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 SMART SM00871 147 299 2.3E-23 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 SUPERFAMILY SSF46689 8 56 4.93E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 Pfam PF06445 GyrI-like small molecule binding domain 149 298 1.9E-13 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 57 101 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 Pfam PF12833 Helix-turn-helix domain 28 106 2.4E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 Gene3D G3DSA:1.10.10.60 7 63 1.7E-9 T 12-10-2018 AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 Gene3D G3DSA:3.20.80.10 145 300 1.0E-42 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 SMART SM00342 22 105 6.3E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 SUPERFAMILY SSF55136 148 299 1.74E-20 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 SUPERFAMILY SSF46689 58 108 1.43E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14235 6f5e76efb6b1195a537f3165fe66e25c 303 Gene3D G3DSA:1.10.10.60 64 111 8.9E-10 T 12-10-2018 AFR_14595 1af2c28e258ab559aceb7d0b08f5ffd0 325 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_14595 1af2c28e258ab559aceb7d0b08f5ffd0 325 SUPERFAMILY SSF52540 1 251 6.23E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14595 1af2c28e258ab559aceb7d0b08f5ffd0 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 315 1.5E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_14595 1af2c28e258ab559aceb7d0b08f5ffd0 325 Gene3D G3DSA:3.40.50.300 1 322 9.3E-92 T 12-10-2018 AFR_14595 1af2c28e258ab559aceb7d0b08f5ffd0 325 Pfam PF00005 ABC transporter 23 180 1.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_14595 1af2c28e258ab559aceb7d0b08f5ffd0 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 297 3.8E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_14595 1af2c28e258ab559aceb7d0b08f5ffd0 325 SMART SM00382 31 229 5.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_24045 31c72e29f443d98b1321c02d2aaa126f 273 SMART SM00530 10 81 4.2E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_24045 31c72e29f443d98b1321c02d2aaa126f 273 Pfam PF13560 Helix-turn-helix domain 6 84 2.5E-17 T 12-10-2018 AFR_24045 31c72e29f443d98b1321c02d2aaa126f 273 SUPERFAMILY SSF47413 29 78 1.27E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_24045 31c72e29f443d98b1321c02d2aaa126f 273 Gene3D G3DSA:1.10.260.40 25 94 1.1E-9 T 12-10-2018 AFR_10110 86ef2e530448f4f15e26a0694917182c 354 Pfam PF00155 Aminotransferase class I and II 28 352 4.9E-57 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_10110 86ef2e530448f4f15e26a0694917182c 354 SUPERFAMILY SSF53383 27 354 1.28E-73 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_10110 86ef2e530448f4f15e26a0694917182c 354 Gene3D G3DSA:3.90.1150.10 13 351 1.5E-123 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_10110 86ef2e530448f4f15e26a0694917182c 354 Gene3D G3DSA:3.40.640.10 50 270 1.5E-123 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_10110 86ef2e530448f4f15e26a0694917182c 354 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFR_10110 86ef2e530448f4f15e26a0694917182c 354 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 354 52.787 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFR_10110 86ef2e530448f4f15e26a0694917182c 354 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 354 1.5E-95 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFR_00385 948131ea16f731beaed5f40e76dde2c9 192 Gene3D G3DSA:2.70.40.10 1 186 1.3E-57 T 12-10-2018 IPR036157 dUTPase-like superfamily AFR_00385 948131ea16f731beaed5f40e76dde2c9 192 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 6.1E-63 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 AFR_00385 948131ea16f731beaed5f40e76dde2c9 192 SUPERFAMILY SSF51283 1 183 1.23E-52 T 12-10-2018 IPR036157 dUTPase-like superfamily AFR_00385 948131ea16f731beaed5f40e76dde2c9 192 Pfam PF00692 dUTPase 60 180 5.6E-11 T 12-10-2018 IPR029054 dUTPase-like AFR_00385 948131ea16f731beaed5f40e76dde2c9 192 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 33.214 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 AFR_12960 159fb0f3164c762154ec3d30939c1e14 288 SMART SM00530 14 87 1.7E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_12960 159fb0f3164c762154ec3d30939c1e14 288 Gene3D G3DSA:1.10.260.40 35 98 7.8E-8 T 12-10-2018 AFR_12960 159fb0f3164c762154ec3d30939c1e14 288 SUPERFAMILY SSF47413 36 83 1.81E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_12960 159fb0f3164c762154ec3d30939c1e14 288 Gene3D G3DSA:3.30.450.180 111 284 8.2E-12 T 12-10-2018 AFR_12960 159fb0f3164c762154ec3d30939c1e14 288 Pfam PF13560 Helix-turn-helix domain 10 90 6.5E-17 T 12-10-2018 AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 Gene3D G3DSA:3.20.80.10 119 277 1.9E-25 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 SUPERFAMILY SSF46955 2 117 1.72E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 SMART SM00422 2 72 1.0E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 SMART SM00871 119 277 6.1E-16 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 SUPERFAMILY SSF55136 120 277 2.17E-17 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 Gene3D G3DSA:1.10.1660.10 1 118 1.0E-21 T 12-10-2018 AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 Pfam PF13411 MerR HTH family regulatory protein 2 71 8.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_08570 60e0ffb6608c79f2f8c0ff1f6e79abc8 280 Pfam PF06445 GyrI-like small molecule binding domain 121 276 1.3E-10 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain AFR_25455 a1f282ba7c24ff044876a3a4d9455de1 169 Gene3D G3DSA:1.10.10.10 81 151 1.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25455 a1f282ba7c24ff044876a3a4d9455de1 169 SUPERFAMILY SSF55811 2 80 2.18E-7 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_25455 a1f282ba7c24ff044876a3a4d9455de1 169 SUPERFAMILY SSF46785 85 154 5.98E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_25455 a1f282ba7c24ff044876a3a4d9455de1 169 Gene3D G3DSA:3.90.79.10 1 80 1.7E-18 T 12-10-2018 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 Pfam PF00072 Response regulator receiver domain 5 115 3.0E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 SUPERFAMILY SSF52172 2 132 7.12E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 Gene3D G3DSA:3.40.50.12740 2 214 7.4E-63 T 12-10-2018 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 SMART SM00448 2 115 9.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 9.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 9.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 9.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 SUPERFAMILY SSF46894 147 213 1.8E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 SMART SM00421 151 208 1.7E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33155 bdb9d088f85f7398e50e52df6e2df268 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 206 4.3E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_36395 0c770c0171e656cf0ab36b543aeccf40 162 Gene3D G3DSA:3.40.33.10 24 160 1.1E-40 T 12-10-2018 IPR035940 CAP superfamily AFR_36395 0c770c0171e656cf0ab36b543aeccf40 162 Pfam PF00188 Cysteine-rich secretory protein family 47 159 2.5E-15 T 12-10-2018 IPR014044 CAP domain AFR_36395 0c770c0171e656cf0ab36b543aeccf40 162 SUPERFAMILY SSF55797 38 160 6.54E-22 T 12-10-2018 IPR035940 CAP superfamily AFR_10115 e5320dc43a4ca6558583c3d0c0e1a487 203 Gene3D G3DSA:3.30.230.40 91 203 1.1E-31 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFR_10115 e5320dc43a4ca6558583c3d0c0e1a487 203 Gene3D G3DSA:3.30.230.40 1 90 1.4E-36 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFR_10115 e5320dc43a4ca6558583c3d0c0e1a487 203 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFR_10115 e5320dc43a4ca6558583c3d0c0e1a487 203 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 182 9.1E-58 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFR_10115 e5320dc43a4ca6558583c3d0c0e1a487 203 SUPERFAMILY SSF54211 88 187 1.39E-25 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_10115 e5320dc43a4ca6558583c3d0c0e1a487 203 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 203 40.647 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFR_10115 e5320dc43a4ca6558583c3d0c0e1a487 203 SUPERFAMILY SSF54211 3 86 1.04E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_30710 c51f213a004500fffeb9236c792d757a 894 Gene3D G3DSA:3.30.54.20 641 694 6.2E-42 T 12-10-2018 AFR_30710 c51f213a004500fffeb9236c792d757a 894 SUPERFAMILY SSF101353 249 451 6.02E-54 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 Gene3D G3DSA:2.40.30.130 492 563 1.7E-11 T 12-10-2018 AFR_30710 c51f213a004500fffeb9236c792d757a 894 SUPERFAMILY SSF55186 569 729 2.75E-44 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AFR_30710 c51f213a004500fffeb9236c792d757a 894 Pfam PF02272 DHHA1 domain 751 890 5.4E-15 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFR_30710 c51f213a004500fffeb9236c792d757a 894 Gene3D G3DSA:3.30.980.10 579 714 6.2E-42 T 12-10-2018 AFR_30710 c51f213a004500fffeb9236c792d757a 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 3.6E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 287 303 3.6E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 311 324 3.6E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 70 81 3.6E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 3.6E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 Pfam PF01411 tRNA synthetases class II (A) 5 571 3.5E-183 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 Gene3D G3DSA:3.30.930.10 1 245 7.2E-92 T 12-10-2018 AFR_30710 c51f213a004500fffeb9236c792d757a 894 SUPERFAMILY SSF55681 2 248 4.72E-85 T 12-10-2018 AFR_30710 c51f213a004500fffeb9236c792d757a 894 SUPERFAMILY SSF50447 471 564 7.77E-15 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_30710 c51f213a004500fffeb9236c792d757a 894 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 894 157.428 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 AFR_30710 c51f213a004500fffeb9236c792d757a 894 Gene3D G3DSA:3.10.310.40 786 891 1.8E-12 T 12-10-2018 AFR_30710 c51f213a004500fffeb9236c792d757a 894 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 670 713 3.6E-15 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFR_30710 c51f213a004500fffeb9236c792d757a 894 SMART SM00863 670 713 4.0E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFR_30710 c51f213a004500fffeb9236c792d757a 894 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 873 5.2E-239 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFR_21000 87722ec3b070b22783c915f5c6ebb993 341 Pfam PF14525 AraC-binding-like domain 43 213 1.9E-31 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_21000 87722ec3b070b22783c915f5c6ebb993 341 SMART SM00342 251 337 7.3E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_21000 87722ec3b070b22783c915f5c6ebb993 341 Gene3D G3DSA:1.10.10.60 235 341 9.7E-31 T 12-10-2018 AFR_21000 87722ec3b070b22783c915f5c6ebb993 341 SUPERFAMILY SSF46689 303 338 1.97E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21000 87722ec3b070b22783c915f5c6ebb993 341 Pfam PF12833 Helix-turn-helix domain 257 338 7.6E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_21000 87722ec3b070b22783c915f5c6ebb993 341 SUPERFAMILY SSF46689 235 285 2.99E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21000 87722ec3b070b22783c915f5c6ebb993 341 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 288 333 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 SMART SM00829 11 334 1.2E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 134 8.0E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 SUPERFAMILY SSF50129 1 171 5.93E-48 T 12-10-2018 IPR011032 GroES-like superfamily AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 SUPERFAMILY SSF51735 139 301 2.48E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 Gene3D G3DSA:3.40.50.720 149 285 9.7E-101 T 12-10-2018 AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 Pfam PF00107 Zinc-binding dehydrogenase 176 292 8.1E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_08615 dc9366d758f6a9d3521873cd77a49372 338 Gene3D G3DSA:3.90.180.10 16 331 9.7E-101 T 12-10-2018 AFR_03570 4a564686851cf350b88c1af196969972 245 SUPERFAMILY SSF51735 6 244 1.71E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 1.4E-55 T 12-10-2018 AFR_03570 4a564686851cf350b88c1af196969972 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.4E-4 T 12-10-2018 AFR_03570 4a564686851cf350b88c1af196969972 245 Gene3D G3DSA:3.40.50.720 1 244 8.7E-73 T 12-10-2018 AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03570 4a564686851cf350b88c1af196969972 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14215 f4930471c6639031591efcfca5c46a30 389 SMART SM00564 288 319 0.079 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFR_14215 f4930471c6639031591efcfca5c46a30 389 SMART SM00564 208 239 41.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFR_14215 f4930471c6639031591efcfca5c46a30 389 SMART SM00564 81 111 13.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFR_14215 f4930471c6639031591efcfca5c46a30 389 Gene3D G3DSA:2.130.10.10 42 243 4.0E-17 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_14215 f4930471c6639031591efcfca5c46a30 389 Pfam PF01011 PQQ enzyme repeat 295 317 1.5E-4 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_14215 f4930471c6639031591efcfca5c46a30 389 Gene3D G3DSA:2.130.10.10 244 389 4.3E-14 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_14215 f4930471c6639031591efcfca5c46a30 389 Pfam PF13360 PQQ-like domain 95 237 1.4E-10 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_14215 f4930471c6639031591efcfca5c46a30 389 SUPERFAMILY SSF50998 258 381 2.67E-12 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_14215 f4930471c6639031591efcfca5c46a30 389 SUPERFAMILY SSF50998 18 283 2.16E-22 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_19260 15c2042c1eb9c36e0771a0b9711c9371 126 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 117 4.0E-27 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_19260 15c2042c1eb9c36e0771a0b9711c9371 126 Gene3D G3DSA:1.20.1290.10 3 125 2.4E-39 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_19260 15c2042c1eb9c36e0771a0b9711c9371 126 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 3 121 2.7E-54 T 12-10-2018 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 AFR_19260 15c2042c1eb9c36e0771a0b9711c9371 126 SUPERFAMILY SSF69118 3 119 1.28E-36 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_27375 a4d4fa23c47477f4cad08259c71a8b45 254 SUPERFAMILY SSF52317 3 232 1.33E-59 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_27375 a4d4fa23c47477f4cad08259c71a8b45 254 Gene3D G3DSA:3.40.50.880 1 241 4.8E-104 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_27375 a4d4fa23c47477f4cad08259c71a8b45 254 PIRSF PIRSF030013 1 241 5.6E-107 T 12-10-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote AFR_27375 a4d4fa23c47477f4cad08259c71a8b45 254 Pfam PF06283 Trehalose utilisation 5 223 3.4E-36 T 12-10-2018 IPR029010 ThuA-like domain AFR_10690 c8fa7b2a6b1654e8c041d3738cc88d1c 151 Pfam PF01592 NifU-like N terminal domain 6 126 1.5E-25 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFR_10690 c8fa7b2a6b1654e8c041d3738cc88d1c 151 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 137 1.8E-45 T 12-10-2018 AFR_10690 c8fa7b2a6b1654e8c041d3738cc88d1c 151 Gene3D G3DSA:3.90.1010.10 1 138 7.0E-45 T 12-10-2018 AFR_10690 c8fa7b2a6b1654e8c041d3738cc88d1c 151 SUPERFAMILY SSF82649 1 137 6.8E-43 T 12-10-2018 AFR_37575 341d0186b4e859739cdf0d0978fd058b 341 SUPERFAMILY SSF51395 5 334 3.36E-90 T 12-10-2018 AFR_37575 341d0186b4e859739cdf0d0978fd058b 341 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 234 240 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AFR_37575 341d0186b4e859739cdf0d0978fd058b 341 Pfam PF01070 FMN-dependent dehydrogenase 7 336 9.4E-126 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AFR_37575 341d0186b4e859739cdf0d0978fd058b 341 Gene3D G3DSA:3.20.20.70 3 340 1.7E-132 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_37575 341d0186b4e859739cdf0d0978fd058b 341 PIRSF PIRSF000138 3 340 1.2E-124 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AFR_20440 3170202b356f5be77de671b6d5cc8a2a 154 SUPERFAMILY SSF46785 5 151 1.42E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20440 3170202b356f5be77de671b6d5cc8a2a 154 SMART SM00347 33 136 2.1E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20440 3170202b356f5be77de671b6d5cc8a2a 154 Pfam PF01047 MarR family 44 98 2.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20440 3170202b356f5be77de671b6d5cc8a2a 154 Gene3D G3DSA:1.10.10.10 7 153 1.0E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01105 f483d0517019719908a2868f7402603f 224 Pfam PF00072 Response regulator receiver domain 3 112 9.7E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_01105 f483d0517019719908a2868f7402603f 224 Gene3D G3DSA:3.40.50.2300 1 123 5.1E-42 T 12-10-2018 AFR_01105 f483d0517019719908a2868f7402603f 224 SMART SM00862 145 220 2.2E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_01105 f483d0517019719908a2868f7402603f 224 SMART SM00448 1 112 2.3E-46 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_01105 f483d0517019719908a2868f7402603f 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 2.8E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_01105 f483d0517019719908a2868f7402603f 224 SUPERFAMILY SSF52172 1 179 4.7E-47 T 12-10-2018 IPR011006 CheY-like superfamily AFR_01105 f483d0517019719908a2868f7402603f 224 Gene3D G3DSA:1.10.10.10 124 223 1.8E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30600 0503099eaef7c7735492522d6e07cd55 276 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 263 1.1E-83 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30600 0503099eaef7c7735492522d6e07cd55 276 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 259 6.0E-32 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30600 0503099eaef7c7735492522d6e07cd55 276 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 91 104 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30600 0503099eaef7c7735492522d6e07cd55 276 SUPERFAMILY SSF51366 4 269 5.18E-60 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_30600 0503099eaef7c7735492522d6e07cd55 276 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 276 33.281 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30600 0503099eaef7c7735492522d6e07cd55 276 Gene3D G3DSA:3.20.20.70 3 275 5.7E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_30600 0503099eaef7c7735492522d6e07cd55 276 SMART SM00934 17 263 1.8E-32 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_27710 ac333c22198e830825b9caef42abff1f 268 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 76 81 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_27710 ac333c22198e830825b9caef42abff1f 268 Gene3D G3DSA:2.40.10.10 65 267 4.7E-19 T 12-10-2018 AFR_27710 ac333c22198e830825b9caef42abff1f 268 Pfam PF00089 Trypsin 62 255 2.6E-15 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_27710 ac333c22198e830825b9caef42abff1f 268 SMART SM00020 43 263 1.5E-5 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_27710 ac333c22198e830825b9caef42abff1f 268 SUPERFAMILY SSF50494 59 255 1.71E-21 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_05565 745d5902278937093216eba947d93e2e 479 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 358 458 7.6E-29 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_05565 745d5902278937093216eba947d93e2e 479 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 234 326 1.3E-30 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_05565 745d5902278937093216eba947d93e2e 479 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 27 202 4.7E-56 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_05565 745d5902278937093216eba947d93e2e 479 SUPERFAMILY SSF52413 350 469 1.27E-32 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFR_05565 745d5902278937093216eba947d93e2e 479 PIRSF PIRSF000124 27 474 1.5E-116 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_05565 745d5902278937093216eba947d93e2e 479 PIRSF PIRSF500134 26 477 5.3E-148 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFR_05565 745d5902278937093216eba947d93e2e 479 Gene3D G3DSA:3.40.50.720 23 219 2.2E-66 T 12-10-2018 AFR_05565 745d5902278937093216eba947d93e2e 479 SMART SM00984 358 459 3.1E-41 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_05565 745d5902278937093216eba947d93e2e 479 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 27 455 5.9E-123 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_05565 745d5902278937093216eba947d93e2e 479 Gene3D G3DSA:1.20.5.100 233 262 5.3E-14 T 12-10-2018 AFR_05565 745d5902278937093216eba947d93e2e 479 SUPERFAMILY SSF48179 233 331 1.62E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_05565 745d5902278937093216eba947d93e2e 479 SUPERFAMILY SSF51735 29 210 4.13E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_05565 745d5902278937093216eba947d93e2e 479 Gene3D G3DSA:3.40.50.720 264 478 2.3E-61 T 12-10-2018 AFR_07995 95158f19d2ef2f40760b115ab9f3dd31 261 Pfam PF02565 Recombination protein O C terminal 99 251 1.5E-32 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFR_07995 95158f19d2ef2f40760b115ab9f3dd31 261 Pfam PF11967 Recombination protein O N terminal 12 91 2.6E-23 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal AFR_07995 95158f19d2ef2f40760b115ab9f3dd31 261 SUPERFAMILY SSF57863 98 247 1.02E-38 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger AFR_07995 95158f19d2ef2f40760b115ab9f3dd31 261 TIGRFAM TIGR00613 reco: DNA repair protein RecO 14 215 2.1E-32 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFR_07995 95158f19d2ef2f40760b115ab9f3dd31 261 Hamap MF_00201 DNA repair protein RecO [recO]. 11 257 26.321 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFR_07995 95158f19d2ef2f40760b115ab9f3dd31 261 Gene3D G3DSA:2.40.50.140 8 95 3.8E-23 T 12-10-2018 AFR_07995 95158f19d2ef2f40760b115ab9f3dd31 261 SUPERFAMILY SSF50249 11 92 7.88E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_05690 6b6120f61e4472e9ddbf865f5445ec2c 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_05690 6b6120f61e4472e9ddbf865f5445ec2c 478 Pfam PF00171 Aldehyde dehydrogenase family 17 469 1.1E-130 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_05690 6b6120f61e4472e9ddbf865f5445ec2c 478 Gene3D G3DSA:3.40.605.10 26 460 1.2E-141 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_05690 6b6120f61e4472e9ddbf865f5445ec2c 478 Gene3D G3DSA:3.40.309.10 250 441 1.2E-141 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_05690 6b6120f61e4472e9ddbf865f5445ec2c 478 SUPERFAMILY SSF53720 4 473 5.76E-129 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_21600 15d139e013e6691efe71045f703cd829 497 SUPERFAMILY SSF51905 2 351 3.92E-65 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_21600 15d139e013e6691efe71045f703cd829 497 Gene3D G3DSA:3.30.70.2450 172 258 1.4E-124 T 12-10-2018 AFR_21600 15d139e013e6691efe71045f703cd829 497 Gene3D G3DSA:3.50.50.60 3 332 1.4E-124 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_21600 15d139e013e6691efe71045f703cd829 497 Pfam PF01494 FAD binding domain 2 334 2.2E-90 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_21600 15d139e013e6691efe71045f703cd829 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 1.2E-45 T 12-10-2018 AFR_21600 15d139e013e6691efe71045f703cd829 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 320 1.2E-45 T 12-10-2018 AFR_21600 15d139e013e6691efe71045f703cd829 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 1.2E-45 T 12-10-2018 AFR_21600 15d139e013e6691efe71045f703cd829 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 1.2E-45 T 12-10-2018 AFR_21600 15d139e013e6691efe71045f703cd829 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 1.2E-45 T 12-10-2018 AFR_21600 15d139e013e6691efe71045f703cd829 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.2E-45 T 12-10-2018 AFR_21600 15d139e013e6691efe71045f703cd829 497 Gene3D G3DSA:3.40.30.120 380 473 6.4E-30 T 12-10-2018 AFR_08565 a6b69ded554f5af32294770d9ca82e99 423 SUPERFAMILY SSF51306 34 121 1.46E-7 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFR_08565 a6b69ded554f5af32294770d9ca82e99 423 Gene3D G3DSA:2.60.120.200 211 420 5.7E-25 T 12-10-2018 AFR_08565 a6b69ded554f5af32294770d9ca82e99 423 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 11 151 7.0E-15 T 12-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFR_08565 a6b69ded554f5af32294770d9ca82e99 423 SMART SM00560 281 412 3.1E-4 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_08565 a6b69ded554f5af32294770d9ca82e99 423 SUPERFAMILY SSF49899 207 420 8.13E-23 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_08565 a6b69ded554f5af32294770d9ca82e99 423 Pfam PF00717 Peptidase S24-like 38 105 1.6E-6 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFR_08565 a6b69ded554f5af32294770d9ca82e99 423 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 269 415 1.9E-20 T 12-10-2018 AFR_19005 a18bf1dfc5ded6e3eb2a58bf42022c77 386 Pfam PF13203 Putative metallopeptidase domain 9 252 2.0E-28 T 12-10-2018 IPR025154 Putative metallopeptidase domain AFR_19005 a18bf1dfc5ded6e3eb2a58bf42022c77 386 Pfam PF09967 VWA-like domain (DUF2201) 258 375 4.4E-17 T 12-10-2018 IPR018698 VWA-like domain AFR_19005 a18bf1dfc5ded6e3eb2a58bf42022c77 386 Gene3D G3DSA:3.40.50.410 252 363 1.5E-6 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_19005 a18bf1dfc5ded6e3eb2a58bf42022c77 386 SUPERFAMILY SSF53300 258 355 9.85E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_20620 d90781b6bae05a013eab3f425b38957a 231 Gene3D G3DSA:3.30.1360.20 15 103 2.5E-8 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_20620 d90781b6bae05a013eab3f425b38957a 231 Gene3D G3DSA:3.10.180.10 110 231 2.3E-7 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_20620 d90781b6bae05a013eab3f425b38957a 231 SUPERFAMILY SSF55248 13 102 9.81E-11 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_20620 d90781b6bae05a013eab3f425b38957a 231 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 8 100 2.0E-10 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_30560 68884db088a3364d7c6993246c88c245 405 SUPERFAMILY SSF48264 17 401 6.55E-97 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 153 168 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 196 218 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 278 289 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 353 364 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 344 353 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 136 152 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 90 101 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 295 322 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00359 B-class P450 signature 323 338 2.3E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 Gene3D G3DSA:1.10.630.10 4 404 2.5E-131 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 Pfam PF00067 Cytochrome P450 180 375 2.5E-32 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00385 P450 superfamily signature 353 364 6.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00385 P450 superfamily signature 344 353 6.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00385 P450 superfamily signature 278 289 6.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30560 68884db088a3364d7c6993246c88c245 405 PRINTS PR00385 P450 superfamily signature 243 260 6.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 1.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 Gene3D G3DSA:1.10.10.10 13 145 9.8E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 Pfam PF13463 Winged helix DNA-binding domain 46 106 1.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 SUPERFAMILY SSF46785 13 148 1.24E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23150 ebfd829bbe82e8de914d5287a3903d6d 167 SMART SM00347 33 133 1.3E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_03100 f3f3c0f256cd9462941081514483f6d9 438 SUPERFAMILY SSF51445 3 362 5.02E-87 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_03100 f3f3c0f256cd9462941081514483f6d9 438 Pfam PF00128 Alpha amylase, catalytic domain 31 316 5.8E-47 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_03100 f3f3c0f256cd9462941081514483f6d9 438 SMART SM00642 14 355 2.3E-53 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_03100 f3f3c0f256cd9462941081514483f6d9 438 Pfam PF11941 Domain of unknown function (DUF3459) 347 429 4.6E-6 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) AFR_03100 f3f3c0f256cd9462941081514483f6d9 438 Gene3D G3DSA:3.20.20.80 2 361 1.9E-83 T 12-10-2018 AFR_12375 f419e707b6c1efed57d0db8e24e875bf 155 Pfam PF00578 AhpC/TSA family 24 137 2.8E-13 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_12375 f419e707b6c1efed57d0db8e24e875bf 155 Gene3D G3DSA:3.40.30.10 21 154 1.1E-28 T 12-10-2018 AFR_12375 f419e707b6c1efed57d0db8e24e875bf 155 SUPERFAMILY SSF52833 24 154 1.45E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_30905 5bacd45e73d5eed625827f6883abebdd 100 PIRSF PIRSF001223 1 100 5.0E-49 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30905 5bacd45e73d5eed625827f6883abebdd 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 3 100 1.9E-46 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30905 5bacd45e73d5eed625827f6883abebdd 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 5.0E-33 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30905 5bacd45e73d5eed625827f6883abebdd 100 SUPERFAMILY SSF54111 2 99 6.93E-44 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30905 5bacd45e73d5eed625827f6883abebdd 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.278 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30905 5bacd45e73d5eed625827f6883abebdd 100 Pfam PF00547 Urease, gamma subunit 3 99 7.9E-45 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30905 5bacd45e73d5eed625827f6883abebdd 100 Gene3D G3DSA:3.30.280.10 2 100 1.7E-45 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_10265 d75ac2b163b3b873511bd46c0be31bcf 200 Gene3D G3DSA:1.10.10.60 5 65 5.8E-26 T 12-10-2018 AFR_10265 d75ac2b163b3b873511bd46c0be31bcf 200 SUPERFAMILY SSF46689 4 70 1.23E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_10265 d75ac2b163b3b873511bd46c0be31bcf 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10265 d75ac2b163b3b873511bd46c0be31bcf 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10265 d75ac2b163b3b873511bd46c0be31bcf 200 Gene3D G3DSA:1.10.357.10 66 195 2.7E-43 T 12-10-2018 AFR_10265 d75ac2b163b3b873511bd46c0be31bcf 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.0E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10265 d75ac2b163b3b873511bd46c0be31bcf 200 SUPERFAMILY SSF48498 84 194 4.0E-29 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 Pfam PF00106 short chain dehydrogenase 16 205 1.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 2.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 SUPERFAMILY SSF51735 14 242 3.56E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 9.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 9.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 9.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 9.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 9.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17945 7294f0c94c4965fb5a5ca32fa2b04bcd 244 Gene3D G3DSA:3.40.50.720 7 244 1.4E-60 T 12-10-2018 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 SUPERFAMILY SSF46894 151 200 2.64E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 SUPERFAMILY SSF52172 6 167 3.53E-22 T 12-10-2018 IPR011006 CheY-like superfamily AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 Gene3D G3DSA:1.10.10.10 107 217 6.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 SMART SM00448 5 125 1.4E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 198 1.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 5.8E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 5.8E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 5.8E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 Gene3D G3DSA:3.40.50.2300 4 102 2.5E-16 T 12-10-2018 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 Pfam PF00072 Response regulator receiver domain 7 102 1.1E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_31480 ff8ea94ed1c62f124dfbe9fdfb2041d7 217 SMART SM00421 151 213 1.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 Gene3D G3DSA:2.40.50.140 1 65 3.7E-31 T 12-10-2018 AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 PIRSF PIRSF002599 1 74 9.8E-27 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 12-10-2018 IPR019844 Cold-shock conserved site AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 SMART SM00357 3 67 2.4E-33 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 SUPERFAMILY SSF50249 1 67 8.43E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 PRINTS PR00050 Cold shock protein signature 25 34 2.0E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 PRINTS PR00050 Cold shock protein signature 40 58 2.0E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 PRINTS PR00050 Cold shock protein signature 4 19 2.0E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_12125 b98cf8e6ed9504de9fe2965397e04272 74 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.5E-32 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 SUPERFAMILY SSF50129 6 185 4.57E-49 T 12-10-2018 IPR011032 GroES-like superfamily AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 149 1.3E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 Gene3D G3DSA:3.90.180.10 16 358 4.8E-110 T 12-10-2018 AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 SMART SM00829 14 359 7.8E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 SUPERFAMILY SSF51735 153 326 6.36E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 SUPERFAMILY SSF50129 314 361 1.18E-5 T 12-10-2018 IPR011032 GroES-like superfamily AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 Pfam PF00107 Zinc-binding dehydrogenase 191 310 4.0E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_38970 fded589af48d7b84cf54d3e2064e08f4 361 Gene3D G3DSA:3.40.50.720 168 304 4.8E-110 T 12-10-2018 AFR_33640 d9a42095374bf790edf62456c85a8536 340 Gene3D G3DSA:1.10.260.40 4 69 3.1E-19 T 12-10-2018 AFR_33640 d9a42095374bf790edf62456c85a8536 340 SUPERFAMILY SSF53822 71 326 1.68E-56 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_33640 d9a42095374bf790edf62456c85a8536 340 Gene3D G3DSA:3.40.50.2300 170 296 1.0E-63 T 12-10-2018 AFR_33640 d9a42095374bf790edf62456c85a8536 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 3.4E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_33640 d9a42095374bf790edf62456c85a8536 340 SMART SM00354 12 83 9.7E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_33640 d9a42095374bf790edf62456c85a8536 340 Pfam PF13377 Periplasmic binding protein-like domain 180 334 3.0E-23 T 12-10-2018 AFR_33640 d9a42095374bf790edf62456c85a8536 340 SUPERFAMILY SSF47413 11 70 3.78E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_33640 d9a42095374bf790edf62456c85a8536 340 Gene3D G3DSA:3.40.50.2300 74 316 1.0E-63 T 12-10-2018 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 SUPERFAMILY SSF50952 204 524 8.24E-13 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Gene3D G3DSA:2.60.120.560 907 1125 1.3E-61 T 12-10-2018 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Pfam PF16990 Carbohydrate binding module (family 35) 672 794 1.1E-12 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Gene3D G3DSA:2.60.120.380 68 170 7.4E-11 T 12-10-2018 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Pfam PF00652 Ricin-type beta-trefoil lectin domain 809 928 3.8E-22 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Gene3D G3DSA:2.60.120.260 670 804 3.9E-35 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_14980 e56793fbe2654186cee440f0795ae504 1126 SMART SM00758 37 177 7.1E-22 T 12-10-2018 IPR011658 PA14 domain AFR_14980 e56793fbe2654186cee440f0795ae504 1126 SUPERFAMILY SSF56988 93 202 1.31E-10 T 12-10-2018 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Gene3D G3DSA:2.80.10.50 805 906 6.8E-28 T 12-10-2018 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Pfam PF06439 Domain of Unknown Function (DUF1080) 936 1124 2.2E-28 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 AFR_14980 e56793fbe2654186cee440f0795ae504 1126 Pfam PF07691 PA14 domain 58 175 1.1E-13 T 12-10-2018 IPR011658 PA14 domain AFR_14980 e56793fbe2654186cee440f0795ae504 1126 SUPERFAMILY SSF50370 808 929 9.44E-31 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_14980 e56793fbe2654186cee440f0795ae504 1126 SMART SM00458 808 931 2.1E-19 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_14980 e56793fbe2654186cee440f0795ae504 1126 SUPERFAMILY SSF49785 670 796 1.42E-22 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25865 f171b4e09b0450f5a213211a541d871f 582 Gene3D G3DSA:3.40.50.300 42 269 1.5E-29 T 12-10-2018 AFR_25865 f171b4e09b0450f5a213211a541d871f 582 Pfam PF00350 Dynamin family 42 201 9.7E-24 T 12-10-2018 IPR022812 Dynamin superfamily AFR_25865 f171b4e09b0450f5a213211a541d871f 582 SUPERFAMILY SSF52540 18 235 4.98E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20280 17526271fc7baad6a0bb8de43839d529 225 SUPERFAMILY SSF46894 154 224 6.12E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 7.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 7.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 7.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 Pfam PF00072 Response regulator receiver domain 14 125 4.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 SUPERFAMILY SSF52172 10 143 7.4E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_20280 17526271fc7baad6a0bb8de43839d529 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 SMART SM00421 162 219 2.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 218 3.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 SMART SM00448 11 124 1.2E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20280 17526271fc7baad6a0bb8de43839d529 225 Gene3D G3DSA:3.40.50.12740 11 225 3.3E-63 T 12-10-2018 AFR_12585 cde26a2cde7e6297e07eb739c42d7656 256 Pfam PF01614 Bacterial transcriptional regulator 123 247 1.7E-34 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_12585 cde26a2cde7e6297e07eb739c42d7656 256 SUPERFAMILY SSF55781 70 251 1.44E-51 T 12-10-2018 AFR_12585 cde26a2cde7e6297e07eb739c42d7656 256 SMART SM00346 5 95 1.2E-17 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_12585 cde26a2cde7e6297e07eb739c42d7656 256 Pfam PF09339 IclR helix-turn-helix domain 7 53 7.9E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_12585 cde26a2cde7e6297e07eb739c42d7656 256 Gene3D G3DSA:1.10.10.10 1 76 4.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12585 cde26a2cde7e6297e07eb739c42d7656 256 Gene3D G3DSA:3.30.450.40 77 253 5.0E-60 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_12585 cde26a2cde7e6297e07eb739c42d7656 256 SUPERFAMILY SSF46785 5 77 6.34E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_25555 b972530d38837c34b70db83ebef6066b 327 SUPERFAMILY SSF47413 1 56 5.63E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_25555 b972530d38837c34b70db83ebef6066b 327 SMART SM00354 1 68 3.9E-30 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_25555 b972530d38837c34b70db83ebef6066b 327 Pfam PF13377 Periplasmic binding protein-like domain 165 323 2.1E-37 T 12-10-2018 AFR_25555 b972530d38837c34b70db83ebef6066b 327 Gene3D G3DSA:3.40.50.2300 74 314 8.8E-73 T 12-10-2018 AFR_25555 b972530d38837c34b70db83ebef6066b 327 Gene3D G3DSA:1.10.260.40 1 54 1.9E-24 T 12-10-2018 AFR_25555 b972530d38837c34b70db83ebef6066b 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 2.7E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_25555 b972530d38837c34b70db83ebef6066b 327 SUPERFAMILY SSF53822 58 326 4.53E-58 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_25555 b972530d38837c34b70db83ebef6066b 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 12-10-2018 AFR_25555 b972530d38837c34b70db83ebef6066b 327 Gene3D G3DSA:3.40.50.2300 156 318 8.8E-73 T 12-10-2018 AFR_05860 86b049980058569e9fbaef6c9069349f 158 Gene3D G3DSA:2.40.280.10 3 130 1.1E-48 T 12-10-2018 IPR023620 Small protein B AFR_05860 86b049980058569e9fbaef6c9069349f 158 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 6.0E-47 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_05860 86b049980058569e9fbaef6c9069349f 158 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 73.117 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_05860 86b049980058569e9fbaef6c9069349f 158 Pfam PF01668 SmpB protein 10 150 1.8E-59 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_05860 86b049980058569e9fbaef6c9069349f 158 SUPERFAMILY SSF74982 4 133 3.92E-52 T 12-10-2018 IPR023620 Small protein B AFR_05860 86b049980058569e9fbaef6c9069349f 158 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site AFR_05860 86b049980058569e9fbaef6c9069349f 158 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 5.0E-57 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_33105 ab5e8b10c11399587de00e85a06fb1ee 155 SMART SM00283 14 146 0.0011 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_33105 ab5e8b10c11399587de00e85a06fb1ee 155 Gene3D G3DSA:1.10.287.950 10 154 1.8E-42 T 12-10-2018 AFR_33105 ab5e8b10c11399587de00e85a06fb1ee 155 SUPERFAMILY SSF58104 14 151 1.31E-43 T 12-10-2018 AFR_33105 ab5e8b10c11399587de00e85a06fb1ee 155 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 20 137 1.5E-31 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 131 214 4.5E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 189 209 6.7E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 20 31 6.7E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 171 187 6.7E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 154 6.7E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 Gene3D G3DSA:3.40.50.1000 19 235 2.9E-31 T 12-10-2018 IPR023214 HAD superfamily AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 143 217 6.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 SUPERFAMILY SSF56784 21 227 8.13E-33 T 12-10-2018 IPR036412 HAD-like superfamily AFR_26325 1ac8a46942bfe42986426e9fe36a0269 248 Pfam PF00702 haloacid dehalogenase-like hydrolase 20 219 2.5E-16 T 12-10-2018 AFR_32490 6ac8f1521bacc5c7da8fe64fd548c8e7 275 Pfam PF00005 ABC transporter 26 176 1.5E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_32490 6ac8f1521bacc5c7da8fe64fd548c8e7 275 SUPERFAMILY SSF52540 8 230 5.23E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32490 6ac8f1521bacc5c7da8fe64fd548c8e7 275 SMART SM00382 34 224 1.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_32490 6ac8f1521bacc5c7da8fe64fd548c8e7 275 Gene3D G3DSA:3.40.50.300 5 242 3.3E-50 T 12-10-2018 AFR_33585 0c3c29bcb046ffd6b2a4b0cdcb2684f3 117 Pfam PF04237 YjbR 13 99 1.1E-8 T 12-10-2018 IPR007351 Uncharacterised protein YjbR AFR_33585 0c3c29bcb046ffd6b2a4b0cdcb2684f3 117 SUPERFAMILY SSF142906 1 110 6.93E-8 T 12-10-2018 IPR038056 YjbR-like superfamily AFR_17710 ffcbcfbf8b9a3985a7fe795f3ebd3657 174 Gene3D G3DSA:1.10.10.10 101 162 9.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17710 ffcbcfbf8b9a3985a7fe795f3ebd3657 174 SUPERFAMILY SSF88946 3 85 7.85E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_17710 ffcbcfbf8b9a3985a7fe795f3ebd3657 174 Pfam PF04542 Sigma-70 region 2 10 74 2.2E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_17710 ffcbcfbf8b9a3985a7fe795f3ebd3657 174 Pfam PF08281 Sigma-70, region 4 103 153 8.2E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_17710 ffcbcfbf8b9a3985a7fe795f3ebd3657 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 155 1.7E-16 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_17710 ffcbcfbf8b9a3985a7fe795f3ebd3657 174 Gene3D G3DSA:1.10.1740.10 1 87 5.0E-12 T 12-10-2018 AFR_17710 ffcbcfbf8b9a3985a7fe795f3ebd3657 174 SUPERFAMILY SSF88659 99 158 4.86E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_33680 7fbfb72d0826df8b76cf0ba03e86f8ee 145 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 15 142 1.7E-28 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_33680 7fbfb72d0826df8b76cf0ba03e86f8ee 145 SUPERFAMILY SSF50475 9 143 8.79E-26 T 12-10-2018 AFR_33680 7fbfb72d0826df8b76cf0ba03e86f8ee 145 Gene3D G3DSA:2.30.110.10 5 144 1.4E-32 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_33680 7fbfb72d0826df8b76cf0ba03e86f8ee 145 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 88 6.1E-11 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_31055 bd700b27392bde6690f913ccd8b5aa82 112 Pfam PF02699 Preprotein translocase subunit 3 78 3.6E-28 T 12-10-2018 IPR003849 Preprotein translocase YajC AFR_31055 bd700b27392bde6690f913ccd8b5aa82 112 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 2 80 4.8E-25 T 12-10-2018 IPR003849 Preprotein translocase YajC AFR_31055 bd700b27392bde6690f913ccd8b5aa82 112 SMART SM01323 1 80 7.2E-38 T 12-10-2018 IPR003849 Preprotein translocase YajC AFR_31055 bd700b27392bde6690f913ccd8b5aa82 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 1 19 2.9E-6 T 12-10-2018 IPR003849 Preprotein translocase YajC AFR_31055 bd700b27392bde6690f913ccd8b5aa82 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 38 56 2.9E-6 T 12-10-2018 IPR003849 Preprotein translocase YajC AFR_14845 72d45a086c4b7be3d11b51d77b04665b 311 Gene3D G3DSA:3.90.180.10 8 308 2.7E-81 T 12-10-2018 AFR_14845 72d45a086c4b7be3d11b51d77b04665b 311 SUPERFAMILY SSF51735 117 282 2.51E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14845 72d45a086c4b7be3d11b51d77b04665b 311 SUPERFAMILY SSF50129 1 149 8.22E-38 T 12-10-2018 IPR011032 GroES-like superfamily AFR_14845 72d45a086c4b7be3d11b51d77b04665b 311 Gene3D G3DSA:3.40.50.720 128 260 2.7E-81 T 12-10-2018 AFR_14845 72d45a086c4b7be3d11b51d77b04665b 311 SMART SM00829 10 309 3.3E-14 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_14845 72d45a086c4b7be3d11b51d77b04665b 311 Pfam PF13602 Zinc-binding dehydrogenase 188 309 1.3E-19 T 12-10-2018 AFR_14845 72d45a086c4b7be3d11b51d77b04665b 311 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 5.6E-8 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_17100 56ffd6deeaeb2a86b3fb44b9d535aad5 133 SUPERFAMILY SSF54427 2 122 4.27E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_17100 56ffd6deeaeb2a86b3fb44b9d535aad5 133 Gene3D G3DSA:3.10.450.50 1 130 2.0E-13 T 12-10-2018 AFR_17100 56ffd6deeaeb2a86b3fb44b9d535aad5 133 Pfam PF13474 SnoaL-like domain 4 125 4.8E-17 T 12-10-2018 IPR037401 SnoaL-like domain AFR_11135 579cf63f38b1a2cb1e38507ac3d6053f 200 Gene3D G3DSA:3.40.430.10 2 199 3.8E-44 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_11135 579cf63f38b1a2cb1e38507ac3d6053f 200 Pfam PF01872 RibD C-terminal domain 7 193 3.2E-19 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_11135 579cf63f38b1a2cb1e38507ac3d6053f 200 SUPERFAMILY SSF53597 7 197 1.57E-25 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_26155 fa43745c029fe618f9d45801db383cd7 845 Gene3D G3DSA:3.40.50.1460 3 247 1.8E-24 T 12-10-2018 AFR_26155 fa43745c029fe618f9d45801db383cd7 845 Pfam PF00656 Caspase domain 4 220 1.8E-12 T 12-10-2018 AFR_26155 fa43745c029fe618f9d45801db383cd7 845 ProSitePatterns PS00018 EF-hand calcium-binding domain. 200 212 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site AFR_26155 fa43745c029fe618f9d45801db383cd7 845 SUPERFAMILY SSF52129 4 201 6.28E-14 T 12-10-2018 IPR029030 Caspase-like domain superfamily AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Gene3D G3DSA:2.115.10.20 193 479 1.0E-68 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Gene3D G3DSA:2.60.120.200 486 685 1.0E-66 T 12-10-2018 AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 132 189 3.7E-12 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 48 126 3.4E-22 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Gene3D G3DSA:2.80.10.50 140 192 5.4E-12 T 12-10-2018 AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 SUPERFAMILY SSF50370 47 186 3.9E-45 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Gene3D G3DSA:2.80.10.50 36 88 2.1E-11 T 12-10-2018 AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Gene3D G3DSA:2.80.10.50 89 139 4.6E-15 T 12-10-2018 AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 SMART SM00458 50 185 2.4E-9 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 Pfam PF04616 Glycosyl hydrolases family 43 196 461 2.0E-34 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 SUPERFAMILY SSF49899 490 684 6.33E-30 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_29190 2992e562024fd5720a5982fd2a88b5fa 689 SUPERFAMILY SSF75005 196 483 2.43E-62 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_22710 a1500d0e2530537f7d89288f31436221 425 SUPERFAMILY SSF53448 49 313 1.41E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_22710 a1500d0e2530537f7d89288f31436221 425 Pfam PF13641 Glycosyltransferase like family 2 58 285 7.5E-33 T 12-10-2018 AFR_22710 a1500d0e2530537f7d89288f31436221 425 Gene3D G3DSA:3.90.550.10 52 274 3.6E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_00735 8af8a86012ee0fef7ddf5350f182b761 110 Gene3D G3DSA:3.30.1050.40 1 110 1.9E-45 T 12-10-2018 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Gene3D G3DSA:3.50.30.10 243 460 3.3E-57 T 12-10-2018 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Gene3D G3DSA:1.10.274.10 260 376 3.3E-57 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Pfam PF03610 PTS system fructose IIA component 3 118 6.9E-23 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 671 689 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Gene3D G3DSA:3.40.50.510 1 129 9.8E-44 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 688 703 2.3E-20 T 12-10-2018 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 723 735 2.3E-20 T 12-10-2018 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 520 539 2.3E-20 T 12-10-2018 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 671 686 2.3E-20 T 12-10-2018 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Gene3D G3DSA:3.20.20.60 461 789 9.8E-100 T 12-10-2018 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Pfam PF00381 PTS HPr component phosphorylation site 150 230 4.0E-20 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 479 763 6.8E-88 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 149 229 1.5E-14 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 2 122 1.5E-34 T 12-10-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Pfam PF00391 PEP-utilising enzyme, mobile domain 380 452 1.7E-17 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 SUPERFAMILY SSF55594 149 232 3.27E-18 T 12-10-2018 IPR035895 HPr-like superfamily AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 SUPERFAMILY SSF53062 1 123 9.29E-29 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Pfam PF05524 PEP-utilising enzyme, N-terminal 243 356 8.7E-26 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 SUPERFAMILY SSF47831 264 373 7.59E-25 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 SUPERFAMILY SSF52009 356 470 2.09E-26 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 243 788 6.0E-126 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 159 166 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 SUPERFAMILY SSF51621 479 765 9.42E-86 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_16385 396e54934d4c4019fee20b45cf1c9239 789 Gene3D G3DSA:3.30.1340.10 148 231 1.5E-22 T 12-10-2018 IPR035895 HPr-like superfamily AFR_33775 30e2e6a7a702790eb6fbd16f2fdebf8f 412 SUPERFAMILY SSF53335 144 407 1.98E-67 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_33775 30e2e6a7a702790eb6fbd16f2fdebf8f 412 PIRSF PIRSF003085 31 412 7.9E-111 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AFR_33775 30e2e6a7a702790eb6fbd16f2fdebf8f 412 Pfam PF02353 Mycolic acid cyclopropane synthetase 139 406 8.8E-79 T 12-10-2018 AFR_33775 30e2e6a7a702790eb6fbd16f2fdebf8f 412 Gene3D G3DSA:3.40.50.150 142 412 1.3E-88 T 12-10-2018 AFR_25290 542a988741293e59520222ab4bd84acd 276 SUPERFAMILY SSF161098 5 276 6.07E-69 T 12-10-2018 IPR035906 MetI-like superfamily AFR_25290 542a988741293e59520222ab4bd84acd 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 267 1.5E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_25290 542a988741293e59520222ab4bd84acd 276 Gene3D G3DSA:1.10.3720.10 2 263 3.9E-63 T 12-10-2018 IPR035906 MetI-like superfamily AFR_16845 f176cab08a35d362db3c21be1d283c0b 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 278 1.1E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_16845 f176cab08a35d362db3c21be1d283c0b 287 Gene3D G3DSA:1.10.3720.10 8 275 3.0E-53 T 12-10-2018 IPR035906 MetI-like superfamily AFR_16845 f176cab08a35d362db3c21be1d283c0b 287 SUPERFAMILY SSF161098 9 287 7.94E-61 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 Gene3D G3DSA:3.40.50.720 1 249 1.8E-71 T 12-10-2018 AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 8 248 1.5E-92 T 12-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 SUPERFAMILY SSF51735 7 248 1.61E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 4.8E-50 T 12-10-2018 AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13055 a2fb8ced12062dab42919d3fa611d80c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35620 f99c17dd1a086f229275301b02d2fe08 292 Gene3D G3DSA:1.10.3720.10 53 270 6.5E-47 T 12-10-2018 IPR035906 MetI-like superfamily AFR_35620 f99c17dd1a086f229275301b02d2fe08 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 268 7.6E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_35620 f99c17dd1a086f229275301b02d2fe08 292 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 65 160 2.6E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFR_35620 f99c17dd1a086f229275301b02d2fe08 292 SUPERFAMILY SSF161098 63 268 1.14E-38 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30975 e94c6bb73d218b94a145b0f6a9b5fab9 230 Pfam PF00005 ABC transporter 20 160 1.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_30975 e94c6bb73d218b94a145b0f6a9b5fab9 230 Gene3D G3DSA:3.40.50.300 1 228 5.6E-62 T 12-10-2018 AFR_30975 e94c6bb73d218b94a145b0f6a9b5fab9 230 SUPERFAMILY SSF52540 1 221 6.63E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30975 e94c6bb73d218b94a145b0f6a9b5fab9 230 SMART SM00382 26 208 8.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_30975 e94c6bb73d218b94a145b0f6a9b5fab9 230 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 230 2.0E-94 T 12-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE AFR_30660 f6007d6106ae96fc024bb962e3e2b8bb 358 SUPERFAMILY SSF56796 10 354 1.03E-95 T 12-10-2018 AFR_30660 f6007d6106ae96fc024bb962e3e2b8bb 358 Pfam PF01761 3-dehydroquinate synthase 66 322 5.2E-88 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFR_30660 f6007d6106ae96fc024bb962e3e2b8bb 358 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 4 358 60.321 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFR_30660 f6007d6106ae96fc024bb962e3e2b8bb 358 Gene3D G3DSA:1.20.1090.10 172 358 7.3E-64 T 12-10-2018 AFR_30660 f6007d6106ae96fc024bb962e3e2b8bb 358 Gene3D G3DSA:3.40.50.1970 1 171 1.2E-52 T 12-10-2018 AFR_30660 f6007d6106ae96fc024bb962e3e2b8bb 358 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 341 3.8E-98 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFR_30660 f6007d6106ae96fc024bb962e3e2b8bb 358 PIRSF PIRSF001455 15 357 1.3E-86 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFR_06275 d8d4e68c3a4b3996c00ed060093b2e08 221 Gene3D G3DSA:1.10.10.60 131 219 2.8E-15 T 12-10-2018 AFR_06275 d8d4e68c3a4b3996c00ed060093b2e08 221 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 175 216 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_06275 d8d4e68c3a4b3996c00ed060093b2e08 221 Pfam PF12833 Helix-turn-helix domain 144 218 1.9E-15 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_06275 d8d4e68c3a4b3996c00ed060093b2e08 221 SMART SM00342 138 220 8.6E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 SUPERFAMILY SSF55424 331 452 7.22E-34 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 6.8E-15 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 292 6.8E-15 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 6.8E-15 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 6.8E-15 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 Gene3D G3DSA:3.50.50.60 2 348 4.5E-157 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 2.0E-14 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 2.0E-14 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.0E-14 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.0E-14 T 12-10-2018 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 315 3.6E-49 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 Gene3D G3DSA:3.50.50.60 115 448 4.5E-157 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 SUPERFAMILY SSF51905 2 323 6.05E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37845 d2c8c74fde484aac40704f5a27e32f46 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 439 2.3E-21 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_23390 db10c3dfeadaf940ecedcb8b60f3107d 280 SUPERFAMILY SSF53448 14 230 6.94E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23390 db10c3dfeadaf940ecedcb8b60f3107d 280 Gene3D G3DSA:3.90.550.10 9 214 2.5E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23390 db10c3dfeadaf940ecedcb8b60f3107d 280 Pfam PF00535 Glycosyl transferase family 2 17 131 8.2E-15 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 Pfam PF00561 alpha/beta hydrolase fold 26 268 5.3E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 229 243 5.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 5.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 Gene3D G3DSA:3.40.50.1820 1 283 6.0E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 PRINTS PR00412 Epoxide hydrolase signature 32 50 2.0E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 PRINTS PR00412 Epoxide hydrolase signature 259 281 2.0E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 PRINTS PR00412 Epoxide hydrolase signature 98 111 2.0E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20195 608751522d78c7b22c0508e69d8f3c62 286 SUPERFAMILY SSF53474 2 283 4.24E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_36800 5207fb09d37b489906f9c193f8776cea 438 SUPERFAMILY SSF63411 16 224 4.89E-59 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_36800 5207fb09d37b489906f9c193f8776cea 438 Pfam PF00675 Insulinase (Peptidase family M16) 27 145 1.3E-20 T 12-10-2018 IPR011765 Peptidase M16, N-terminal AFR_36800 5207fb09d37b489906f9c193f8776cea 438 Gene3D G3DSA:3.30.830.10 14 236 9.5E-73 T 12-10-2018 AFR_36800 5207fb09d37b489906f9c193f8776cea 438 Gene3D G3DSA:3.30.830.10 244 438 1.5E-32 T 12-10-2018 AFR_36800 5207fb09d37b489906f9c193f8776cea 438 Pfam PF05193 Peptidase M16 inactive domain 186 366 7.1E-25 T 12-10-2018 IPR007863 Peptidase M16, C-terminal AFR_36800 5207fb09d37b489906f9c193f8776cea 438 SUPERFAMILY SSF63411 253 435 5.67E-25 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_14985 80a85ec7b6fbf63aa49ce6b50fbfcfa1 410 SUPERFAMILY SSF141868 4 191 1.83E-9 T 12-10-2018 IPR035919 EAL domain superfamily AFR_14985 80a85ec7b6fbf63aa49ce6b50fbfcfa1 410 PIRSF PIRSF003180 8 394 2.2E-65 T 12-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing AFR_14985 80a85ec7b6fbf63aa49ce6b50fbfcfa1 410 Gene3D G3DSA:1.10.3210.10 192 372 4.0E-23 T 12-10-2018 AFR_14985 80a85ec7b6fbf63aa49ce6b50fbfcfa1 410 Pfam PF08668 HDOD domain 204 321 1.4E-15 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD AFR_14985 80a85ec7b6fbf63aa49ce6b50fbfcfa1 410 SUPERFAMILY SSF109604 179 373 6.59E-30 T 12-10-2018 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 2.6E-26 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 SUPERFAMILY SSF47203 238 382 4.67E-30 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 3.3E-25 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 Gene3D G3DSA:2.40.110.10 122 234 2.1E-31 T 12-10-2018 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 Gene3D G3DSA:1.10.540.10 3 119 4.0E-30 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 SUPERFAMILY SSF56645 5 234 1.44E-62 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 215 8.1E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_11245 7e7221fd9d653c4141bf512813336cbe 398 Gene3D G3DSA:1.20.140.10 235 392 2.9E-26 T 12-10-2018 AFR_05890 159bce3ddd8b91809fd34bdbeca3ae44 268 Pfam PF01048 Phosphorylase superfamily 10 239 3.5E-41 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFR_05890 159bce3ddd8b91809fd34bdbeca3ae44 268 SUPERFAMILY SSF53167 9 261 1.38E-82 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFR_05890 159bce3ddd8b91809fd34bdbeca3ae44 268 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 10 244 1.4E-94 T 12-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AFR_05890 159bce3ddd8b91809fd34bdbeca3ae44 268 Gene3D G3DSA:3.40.50.1580 2 263 1.2E-88 T 12-10-2018 AFR_05890 159bce3ddd8b91809fd34bdbeca3ae44 268 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 8 263 42.867 T 12-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AFR_30100 7dd72f88c410b5d021c965eb75333fbb 312 SUPERFAMILY SSF161098 73 299 2.75E-63 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30100 7dd72f88c410b5d021c965eb75333fbb 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 302 5.3E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30100 7dd72f88c410b5d021c965eb75333fbb 312 Gene3D G3DSA:1.10.3720.10 69 311 8.7E-73 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41195 698b76ebc31e3115028eeed2da54b826 370 Gene3D G3DSA:3.30.420.40 71 166 1.0E-8 T 12-10-2018 AFR_41195 698b76ebc31e3115028eeed2da54b826 370 Gene3D G3DSA:1.10.10.10 6 66 2.3E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_41195 698b76ebc31e3115028eeed2da54b826 370 SUPERFAMILY SSF53067 195 366 4.26E-26 T 12-10-2018 AFR_41195 698b76ebc31e3115028eeed2da54b826 370 SUPERFAMILY SSF46785 8 65 3.52E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41195 698b76ebc31e3115028eeed2da54b826 370 ProSitePatterns PS01125 ROK family signature. 199 226 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_41195 698b76ebc31e3115028eeed2da54b826 370 SUPERFAMILY SSF53067 72 187 3.89E-11 T 12-10-2018 AFR_41195 698b76ebc31e3115028eeed2da54b826 370 Gene3D G3DSA:3.30.420.40 173 364 3.9E-30 T 12-10-2018 AFR_41195 698b76ebc31e3115028eeed2da54b826 370 Pfam PF00480 ROK family 106 358 1.1E-30 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_12635 7230033c17fc3119f19e951c3f12b770 194 SUPERFAMILY SSF48498 85 175 3.2E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12635 7230033c17fc3119f19e951c3f12b770 194 Gene3D G3DSA:1.10.10.60 1 59 4.5E-17 T 12-10-2018 AFR_12635 7230033c17fc3119f19e951c3f12b770 194 SUPERFAMILY SSF46689 5 85 6.16E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12635 7230033c17fc3119f19e951c3f12b770 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12635 7230033c17fc3119f19e951c3f12b770 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12635 7230033c17fc3119f19e951c3f12b770 194 Gene3D G3DSA:1.10.357.10 60 189 1.8E-15 T 12-10-2018 AFR_12635 7230033c17fc3119f19e951c3f12b770 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 7.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_30895 bec44567a8974c85bee737e9afd16e0a 125 SUPERFAMILY SSF55298 2 124 1.08E-33 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_30895 bec44567a8974c85bee737e9afd16e0a 125 Pfam PF01042 Endoribonuclease L-PSP 11 122 1.5E-25 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_30895 bec44567a8974c85bee737e9afd16e0a 125 Gene3D G3DSA:3.30.1330.40 2 124 1.0E-34 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_33170 b3a9497e2b20b74bca31337eeca52e31 704 Pfam PF00916 Sulfate permease family 5 353 1.0E-67 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFR_33170 b3a9497e2b20b74bca31337eeca52e31 704 Gene3D G3DSA:3.40.1050.10 504 702 9.6E-57 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_33170 b3a9497e2b20b74bca31337eeca52e31 704 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 550 557 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_33170 b3a9497e2b20b74bca31337eeca52e31 704 Pfam PF00484 Carbonic anhydrase 546 689 7.8E-41 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_33170 b3a9497e2b20b74bca31337eeca52e31 704 SUPERFAMILY SSF53056 504 694 3.53E-50 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_33170 b3a9497e2b20b74bca31337eeca52e31 704 SMART SM00947 538 694 1.7E-56 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_16335 067c24b02b0e017c12fb915d68fab35b 467 Gene3D G3DSA:1.10.510.10 198 350 1.3E-5 T 12-10-2018 AFR_16335 067c24b02b0e017c12fb915d68fab35b 467 SUPERFAMILY SSF56112 204 335 3.84E-9 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_03740 2891c4d51547662d54a75ff2f596c7e3 251 Pfam PF05368 NmrA-like family 87 186 1.4E-4 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 AFR_03740 2891c4d51547662d54a75ff2f596c7e3 251 SUPERFAMILY SSF51735 1 235 6.38E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03740 2891c4d51547662d54a75ff2f596c7e3 251 Gene3D G3DSA:3.40.50.720 22 229 1.3E-44 T 12-10-2018 AFR_03740 2891c4d51547662d54a75ff2f596c7e3 251 Gene3D G3DSA:3.90.25.10 102 230 1.3E-44 T 12-10-2018 AFR_12650 7dff25794fb6f677aa245a9454d8a3ea 320 SUPERFAMILY SSF46785 5 63 2.4E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_12650 7dff25794fb6f677aa245a9454d8a3ea 320 Pfam PF08279 HTH domain 7 62 6.2E-15 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_12650 7dff25794fb6f677aa245a9454d8a3ea 320 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFR_12650 7dff25794fb6f677aa245a9454d8a3ea 320 Pfam PF13280 WYL domain 143 315 3.4E-28 T 12-10-2018 IPR026881 WYL domain AFR_12650 7dff25794fb6f677aa245a9454d8a3ea 320 Gene3D G3DSA:1.10.10.10 4 65 5.9E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12650 7dff25794fb6f677aa245a9454d8a3ea 320 PIRSF PIRSF016838 2 318 2.0E-22 T 12-10-2018 IPR028349 Protein PafC AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 547 557 6.3E-27 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 421 435 6.3E-27 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 619 6.3E-27 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 536 6.3E-27 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 635 6.3E-27 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 271 285 6.3E-27 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 SUPERFAMILY SSF55008 3 68 1.7E-16 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 423 429 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 199 680 2.3E-81 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 Gene3D G3DSA:3.40.1110.10 432 532 6.5E-77 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 37 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 Gene3D G3DSA:2.70.150.20 212 325 3.8E-36 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 SUPERFAMILY SSF81665 205 413 3.14E-6 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 SUPERFAMILY SSF81653 236 321 6.41E-23 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00943 Copper-transporting ATPase signature 577 594 5.6E-5 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00943 Copper-transporting ATPase signature 130 149 5.6E-5 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00943 Copper-transporting ATPase signature 634 648 5.6E-5 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00943 Copper-transporting ATPase signature 404 419 5.6E-5 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 PRINTS PR00943 Copper-transporting ATPase signature 344 358 5.6E-5 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 192 703 4.6E-121 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 SUPERFAMILY SSF56784 419 700 5.5E-56 T 12-10-2018 IPR036412 HAD-like superfamily AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 Pfam PF00403 Heavy-metal-associated domain 8 65 1.8E-10 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 Pfam PF00702 haloacid dehalogenase-like hydrolase 417 614 6.4E-41 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 Pfam PF00122 E1-E2 ATPase 235 399 1.5E-52 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 Gene3D G3DSA:3.30.70.100 1 69 7.8E-18 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 189 703 3.4E-154 T 12-10-2018 AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 Gene3D G3DSA:3.40.50.1000 402 652 6.5E-77 T 12-10-2018 IPR023214 HAD superfamily AFR_37120 05be0c2097d3308bdbf81fd8f30e9241 712 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 145 702 3.0E-168 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 193 304 3.9E-9 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Gene3D G3DSA:3.40.250.10 330 480 7.6E-43 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 SUPERFAMILY SSF52821 498 610 7.33E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 SUPERFAMILY SSF52821 337 477 6.16E-36 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 SUPERFAMILY SSF51735 2 159 3.04E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Gene3D G3DSA:3.40.250.10 489 609 2.0E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Gene3D G3DSA:1.10.1040.10 193 310 1.7E-11 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Pfam PF00581 Rhodanese-like domain 341 462 1.2E-15 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Pfam PF00581 Rhodanese-like domain 498 599 1.5E-8 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 164 6.5E-24 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 SUPERFAMILY SSF48179 191 305 2.04E-10 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 SMART SM00450 341 466 2.8E-21 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 SMART SM00450 485 603 2.6E-10 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_22245 b69d1d446f337a8ac5ccae709db6861d 614 Gene3D G3DSA:3.40.50.720 2 190 6.0E-38 T 12-10-2018 AFR_21635 38cdef9cefed22dd9ae934e477d728b7 355 Pfam PF00701 Dihydrodipicolinate synthetase family 12 281 1.0E-43 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_21635 38cdef9cefed22dd9ae934e477d728b7 355 SMART SM01130 11 289 1.0E-62 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFR_21635 38cdef9cefed22dd9ae934e477d728b7 355 Gene3D G3DSA:3.20.20.70 9 292 3.4E-62 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_21635 38cdef9cefed22dd9ae934e477d728b7 355 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 AFR_21635 38cdef9cefed22dd9ae934e477d728b7 355 SUPERFAMILY SSF51569 12 287 2.72E-59 T 12-10-2018 AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 7.6E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 SUPERFAMILY SSF46689 78 137 3.89E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 Gene3D G3DSA:1.10.10.10 5 79 7.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 SMART SM00345 9 68 1.2E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 Pfam PF00440 Bacterial regulatory proteins, tetR family 85 128 2.1E-4 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 Gene3D G3DSA:1.10.357.10 138 296 5.3E-38 T 12-10-2018 AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 146 291 4.1E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 SUPERFAMILY SSF48498 149 296 5.56E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 SUPERFAMILY SSF46785 3 72 7.39E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26600 a40a4ad938586e93ac2dd83a78860998 296 Gene3D G3DSA:1.10.10.60 80 137 1.3E-22 T 12-10-2018 AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 Gene3D G3DSA:1.10.10.60 1 66 3.2E-25 T 12-10-2018 AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 Gene3D G3DSA:1.10.357.10 70 190 1.9E-17 T 12-10-2018 AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 2.0E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 SUPERFAMILY SSF48498 83 188 6.04E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 SUPERFAMILY SSF46689 1 66 1.5E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11965 25fab885ebbc0c98e384d88c6dd4712f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_42720 11fe3487fd16e7fb4d1551fd91ea6e9e 143 Gene3D G3DSA:3.90.1170.40 2 141 2.5E-42 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFR_42720 11fe3487fd16e7fb4d1551fd91ea6e9e 143 Pfam PF02391 MoaE protein 12 123 5.9E-33 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFR_42720 11fe3487fd16e7fb4d1551fd91ea6e9e 143 SUPERFAMILY SSF54690 12 141 4.84E-38 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFR_17050 57303b5a4b85105d7d092c6fe8824600 200 Gene3D G3DSA:1.10.357.10 1 199 1.6E-13 T 12-10-2018 AFR_17050 57303b5a4b85105d7d092c6fe8824600 200 SUPERFAMILY SSF46689 1 63 4.77E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_17050 57303b5a4b85105d7d092c6fe8824600 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 52 2.0E-4 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_05925 4ecf1afcda2199277a19e6d503f852db 302 SUPERFAMILY SSF51679 12 298 3.39E-45 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_05925 4ecf1afcda2199277a19e6d503f852db 302 Pfam PF00296 Luciferase-like monooxygenase 11 209 9.8E-34 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_05925 4ecf1afcda2199277a19e6d503f852db 302 Gene3D G3DSA:3.20.20.30 3 300 8.0E-50 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_36065 19f41893816054c9de99e314247ccfb7 132 SUPERFAMILY SSF46955 13 81 5.49E-10 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_36065 19f41893816054c9de99e314247ccfb7 132 Gene3D G3DSA:1.10.1660.10 8 81 6.9E-15 T 12-10-2018 AFR_36065 19f41893816054c9de99e314247ccfb7 132 Pfam PF13411 MerR HTH family regulatory protein 13 74 2.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_36065 19f41893816054c9de99e314247ccfb7 132 SMART SM00422 13 81 4.5E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_08755 a94b31fd8faff294cfdbf0335723498a 198 Gene3D G3DSA:1.10.3300.10 52 196 1.2E-23 T 12-10-2018 IPR023286 ABATE domain superfamily AFR_08755 a94b31fd8faff294cfdbf0335723498a 198 Pfam PF11706 CGNR zinc finger 152 194 1.6E-19 T 12-10-2018 IPR021005 Zinc finger, CGNR AFR_08755 a94b31fd8faff294cfdbf0335723498a 198 Pfam PF07336 Putative stress-induced transcription regulator 16 146 5.7E-14 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator AFR_08755 a94b31fd8faff294cfdbf0335723498a 198 SUPERFAMILY SSF160904 12 194 2.48E-35 T 12-10-2018 AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 Gene3D G3DSA:3.40.190.10 109 284 7.7E-23 T 12-10-2018 AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 SUPERFAMILY SSF53850 106 301 6.15E-19 T 12-10-2018 AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 Gene3D G3DSA:1.10.10.10 2 90 1.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 Gene3D G3DSA:3.40.190.10 174 272 7.7E-23 T 12-10-2018 AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 SUPERFAMILY SSF46785 3 84 2.94E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.9E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 Pfam PF03466 LysR substrate binding domain 102 296 8.3E-21 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_26690 6350062a1c677bb526d6a24ff1f3eca0 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13215 81ca9fde6eb1b22c6ffee2f242bb26ec 310 SMART SM00829 10 307 1.0E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_13215 81ca9fde6eb1b22c6ffee2f242bb26ec 310 Gene3D G3DSA:3.90.180.10 8 306 2.8E-65 T 12-10-2018 AFR_13215 81ca9fde6eb1b22c6ffee2f242bb26ec 310 Gene3D G3DSA:3.40.50.720 128 258 2.8E-65 T 12-10-2018 AFR_13215 81ca9fde6eb1b22c6ffee2f242bb26ec 310 SUPERFAMILY SSF51735 117 280 4.23E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13215 81ca9fde6eb1b22c6ffee2f242bb26ec 310 Pfam PF13602 Zinc-binding dehydrogenase 204 307 7.1E-9 T 12-10-2018 AFR_13215 81ca9fde6eb1b22c6ffee2f242bb26ec 310 SUPERFAMILY SSF50129 1 154 6.39E-37 T 12-10-2018 IPR011032 GroES-like superfamily AFR_13215 81ca9fde6eb1b22c6ffee2f242bb26ec 310 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 2.6E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_06450 73d8003f545ba71994e061b714abc153 296 SUPERFAMILY SSF46689 171 276 6.63E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06450 73d8003f545ba71994e061b714abc153 296 SMART SM00507 89 145 0.0032 T 12-10-2018 IPR003615 HNH nuclease AFR_12405 c90e01770626597dbedeb0b359105b2a 427 SUPERFAMILY SSF56601 6 301 1.05E-54 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_12405 c90e01770626597dbedeb0b359105b2a 427 Gene3D G3DSA:3.40.710.10 2 300 6.5E-56 T 12-10-2018 AFR_12405 c90e01770626597dbedeb0b359105b2a 427 Pfam PF00144 Beta-lactamase 6 289 2.2E-42 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_05700 10c3553fc1600ab3161145d43f65f6a8 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_05700 10c3553fc1600ab3161145d43f65f6a8 507 Pfam PF00171 Aldehyde dehydrogenase family 31 494 3.8E-159 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_05700 10c3553fc1600ab3161145d43f65f6a8 507 SUPERFAMILY SSF53720 16 499 1.31E-157 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_05700 10c3553fc1600ab3161145d43f65f6a8 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_05700 10c3553fc1600ab3161145d43f65f6a8 507 Gene3D G3DSA:3.40.605.10 24 493 4.3E-158 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_05700 10c3553fc1600ab3161145d43f65f6a8 507 Gene3D G3DSA:3.40.309.10 267 465 4.3E-158 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_04810 ead367f063fba2243c8590d045245818 627 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 627 40.302 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFR_04810 ead367f063fba2243c8590d045245818 627 Pfam PF13522 Glutamine amidotransferase domain 71 201 1.8E-19 T 12-10-2018 AFR_04810 ead367f063fba2243c8590d045245818 627 Pfam PF01380 SIS domain 476 606 1.8E-21 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_04810 ead367f063fba2243c8590d045245818 627 Pfam PF01380 SIS domain 304 428 4.1E-34 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_04810 ead367f063fba2243c8590d045245818 627 SUPERFAMILY SSF53697 259 627 7.89E-112 T 12-10-2018 AFR_04810 ead367f063fba2243c8590d045245818 627 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 627 1.1E-241 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFR_04810 ead367f063fba2243c8590d045245818 627 SUPERFAMILY SSF56235 2 244 1.46E-63 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_04810 ead367f063fba2243c8590d045245818 627 Gene3D G3DSA:3.40.50.10490 461 612 1.9E-140 T 12-10-2018 AFR_04810 ead367f063fba2243c8590d045245818 627 Gene3D G3DSA:3.40.50.10490 261 626 1.9E-140 T 12-10-2018 AFR_04810 ead367f063fba2243c8590d045245818 627 Gene3D G3DSA:3.60.20.10 2 253 5.8E-71 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_10240 0a73c7fa0845d1dbe92c7a4ff526983f 209 SUPERFAMILY SSF109854 3 113 8.7E-6 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_10240 0a73c7fa0845d1dbe92c7a4ff526983f 209 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 184 9.9E-29 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_10240 0a73c7fa0845d1dbe92c7a4ff526983f 209 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 202 4.9E-64 T 12-10-2018 IPR017519 Conserved hypothetical protein CHP03085 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Gene3D G3DSA:3.40.50.12780 27 409 7.7E-91 T 12-10-2018 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 SMART SM00823 Phosphopantetheine attachment site 521 589 0.0017 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 SUPERFAMILY SSF51161 1180 1293 3.88E-18 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 SUPERFAMILY SSF56801 29 534 7.98E-107 T 12-10-2018 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 SUPERFAMILY SSF51161 724 821 2.08E-19 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Gene3D G3DSA:2.160.10.10 1194 1298 1.9E-11 T 12-10-2018 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 SUPERFAMILY SSF51161 890 1058 6.24E-12 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Gene3D G3DSA:1.10.1200.10 507 591 1.7E-14 T 12-10-2018 IPR036736 ACP-like superfamily AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 608 1293 1.7E-213 T 12-10-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 780 808 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Gene3D G3DSA:3.30.300.30 410 506 8.0E-21 T 12-10-2018 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Pfam PF00550 Phosphopantetheine attachment site 523 583 9.3E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 61 438 2.9E-96 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Gene3D G3DSA:2.160.10.10 707 828 3.0E-14 T 12-10-2018 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Pfam PF00501 AMP-binding enzyme 47 414 1.2E-64 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 SUPERFAMILY SSF47336 517 585 2.02E-11 T 12-10-2018 IPR036736 ACP-like superfamily AFR_15525 fb245afbc4f4bc1a67220e36ce3b8889 1303 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 772 806 5.4E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFR_32440 5f173be2fb0ce3d0d6020c4830051600 590 SUPERFAMILY SSF56112 40 347 1.45E-83 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_32440 5f173be2fb0ce3d0d6020c4830051600 590 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 161 173 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_32440 5f173be2fb0ce3d0d6020c4830051600 590 Pfam PF00069 Protein kinase domain 44 293 2.4E-57 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_32440 5f173be2fb0ce3d0d6020c4830051600 590 Gene3D G3DSA:1.10.510.10 37 303 8.7E-77 T 12-10-2018 AFR_32440 5f173be2fb0ce3d0d6020c4830051600 590 SMART SM00220 42 300 5.0E-80 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_32440 5f173be2fb0ce3d0d6020c4830051600 590 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 48 71 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_01480 24fd14128ce572cb7daa37dbd7df1b08 131 Pfam PF14012 Protein of unknown function (DUF4229) 6 66 1.4E-14 T 12-10-2018 IPR025323 Protein of unknown function DUF4229 AFR_22995 ee06f266734837685782cc8f8d516507 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 100 1.0E-17 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_22995 ee06f266734837685782cc8f8d516507 107 SUPERFAMILY SSF52091 4 100 5.89E-19 T 12-10-2018 IPR036513 STAS domain superfamily AFR_22995 ee06f266734837685782cc8f8d516507 107 Pfam PF13466 STAS domain 20 97 5.7E-15 T 12-10-2018 IPR002645 STAS domain AFR_22995 ee06f266734837685782cc8f8d516507 107 Gene3D G3DSA:3.30.750.24 7 107 2.4E-22 T 12-10-2018 IPR036513 STAS domain superfamily AFR_08200 79b1fd7611292fc911fceed385a232b7 392 Gene3D G3DSA:3.30.420.40 197 370 8.0E-86 T 12-10-2018 AFR_08200 79b1fd7611292fc911fceed385a232b7 392 Gene3D G3DSA:1.10.10.10 8 69 6.8E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08200 79b1fd7611292fc911fceed385a232b7 392 Gene3D G3DSA:3.30.420.40 80 380 8.0E-86 T 12-10-2018 AFR_08200 79b1fd7611292fc911fceed385a232b7 392 SUPERFAMILY SSF53067 75 387 1.01E-53 T 12-10-2018 AFR_08200 79b1fd7611292fc911fceed385a232b7 392 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 50 3.1E-6 T 12-10-2018 AFR_08200 79b1fd7611292fc911fceed385a232b7 392 SUPERFAMILY SSF46785 3 68 4.4E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_08200 79b1fd7611292fc911fceed385a232b7 392 ProSitePatterns PS01125 ROK family signature. 207 234 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_08200 79b1fd7611292fc911fceed385a232b7 392 Pfam PF00480 ROK family 76 385 1.6E-54 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 Pfam PF00072 Response regulator receiver domain 4 115 7.8E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 SUPERFAMILY SSF46894 151 223 4.08E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 SMART SM00421 159 216 3.1E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 SMART SM00448 2 117 1.7E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 1.6E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 Gene3D G3DSA:3.40.50.12740 2 222 2.6E-69 T 12-10-2018 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 SUPERFAMILY SSF52172 1 135 1.27E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 3.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 3.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11305 246c5db73ec5ef1ced5ae3ecd0a65f9d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 3.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_37140 21a7db439274693961ea1fc8d6cc4e8b 642 SUPERFAMILY SSF56601 292 640 4.27E-62 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_37140 21a7db439274693961ea1fc8d6cc4e8b 642 SUPERFAMILY SSF56519 156 343 5.36E-18 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFR_37140 21a7db439274693961ea1fc8d6cc4e8b 642 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 33 146 9.8E-11 T 12-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 AFR_37140 21a7db439274693961ea1fc8d6cc4e8b 642 Gene3D G3DSA:3.90.1310.30 153 339 9.9E-16 T 12-10-2018 AFR_37140 21a7db439274693961ea1fc8d6cc4e8b 642 Gene3D G3DSA:3.40.710.10 340 642 6.9E-62 T 12-10-2018 AFR_37140 21a7db439274693961ea1fc8d6cc4e8b 642 Pfam PF00905 Penicillin binding protein transpeptidase domain 366 637 7.5E-47 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_37140 21a7db439274693961ea1fc8d6cc4e8b 642 Pfam PF03717 Penicillin-binding Protein dimerisation domain 155 316 4.0E-16 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 SUPERFAMILY SSF48452 104 265 2.4E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 Gene3D G3DSA:1.25.40.10 107 272 2.0E-46 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 Gene3D G3DSA:1.10.10.10 1 105 3.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 SMART SM00862 22 102 1.5E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 Pfam PF03704 Bacterial transcriptional activator domain 109 252 1.4E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 Pfam PF13191 AAA ATPase domain 268 406 1.3E-13 T 12-10-2018 AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 SMART SM01043 109 253 2.5E-45 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 83 2.3E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 SUPERFAMILY SSF46894 8 84 1.62E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_02580 bf83d5b4336e10083d7fa9c4f370bdcc 767 SUPERFAMILY SSF52540 261 476 5.41E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03250 558d40914e84a085022a1a7525ade13e 357 Gene3D G3DSA:3.40.50.2300 157 357 7.8E-129 T 12-10-2018 AFR_03250 558d40914e84a085022a1a7525ade13e 357 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 57 357 2.3E-119 T 12-10-2018 IPR013459 Rhamnose ABC transporter, substrate-binding protein RhaS GO:0015762 AFR_03250 558d40914e84a085022a1a7525ade13e 357 Pfam PF13407 Periplasmic binding protein domain 57 314 6.7E-54 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_03250 558d40914e84a085022a1a7525ade13e 357 SUPERFAMILY SSF53822 54 357 9.03E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_03250 558d40914e84a085022a1a7525ade13e 357 Gene3D G3DSA:3.40.50.2300 56 341 7.8E-129 T 12-10-2018 AFR_40890 3877149ad27905064a0a3f1e2d031b20 174 SUPERFAMILY SSF55729 7 162 8.75E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40890 3877149ad27905064a0a3f1e2d031b20 174 Pfam PF00583 Acetyltransferase (GNAT) family 57 148 8.0E-13 T 12-10-2018 IPR000182 GNAT domain AFR_40890 3877149ad27905064a0a3f1e2d031b20 174 Gene3D G3DSA:3.40.630.30 9 161 9.5E-24 T 12-10-2018 AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 SMART SM00342 226 309 4.8E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 SUPERFAMILY SSF46689 263 312 9.73E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 Gene3D G3DSA:1.10.10.60 210 316 2.9E-24 T 12-10-2018 AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 Pfam PF12833 Helix-turn-helix domain 232 310 1.2E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 Pfam PF01965 DJ-1/PfpI family 5 171 6.2E-19 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 SUPERFAMILY SSF46689 212 259 4.3E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 Gene3D G3DSA:3.40.50.880 2 205 3.7E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 SUPERFAMILY SSF52317 3 192 1.49E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_19095 5670b316035120ae53c65f3a1ecd5cee 317 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 263 305 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_19760 a15fc6e4447c32582007de47c4f2fd52 275 Pfam PF00561 alpha/beta hydrolase fold 22 136 1.2E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19760 a15fc6e4447c32582007de47c4f2fd52 275 Pfam PF08386 TAP-like protein 198 256 2.1E-4 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal AFR_19760 a15fc6e4447c32582007de47c4f2fd52 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 2.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19760 a15fc6e4447c32582007de47c4f2fd52 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19760 a15fc6e4447c32582007de47c4f2fd52 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19760 a15fc6e4447c32582007de47c4f2fd52 275 Gene3D G3DSA:3.40.50.1820 1 275 3.6E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19760 a15fc6e4447c32582007de47c4f2fd52 275 SUPERFAMILY SSF53474 2 272 7.92E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_07430 bf1c4f53e6e3e75c4a61edb5f71a0a8e 147 SMART SM00507 45 94 1.2E-11 T 12-10-2018 IPR003615 HNH nuclease AFR_07430 bf1c4f53e6e3e75c4a61edb5f71a0a8e 147 Pfam PF14279 HNH endonuclease 58 105 4.7E-14 T 12-10-2018 IPR029471 HNH endonuclease 5 AFR_07430 bf1c4f53e6e3e75c4a61edb5f71a0a8e 147 Gene3D G3DSA:3.30.40.60 35 120 3.1E-20 T 12-10-2018 AFR_11450 357fdf71fad5b44a45d6c7e5229a3750 217 Gene3D G3DSA:1.10.10.10 120 217 3.6E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11450 357fdf71fad5b44a45d6c7e5229a3750 217 SMART SM00448 1 110 3.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11450 357fdf71fad5b44a45d6c7e5229a3750 217 Gene3D G3DSA:3.40.50.2300 1 119 5.0E-28 T 12-10-2018 AFR_11450 357fdf71fad5b44a45d6c7e5229a3750 217 SMART SM00862 142 215 2.6E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_11450 357fdf71fad5b44a45d6c7e5229a3750 217 SUPERFAMILY SSF52172 1 171 3.15E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_11450 357fdf71fad5b44a45d6c7e5229a3750 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 8.5E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_11450 357fdf71fad5b44a45d6c7e5229a3750 217 Pfam PF00072 Response regulator receiver domain 1 110 3.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_04010 97d0f0802c88c0852627aef701d2f349 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 193 1.2E-4 T 12-10-2018 AFR_04010 97d0f0802c88c0852627aef701d2f349 257 SUPERFAMILY SSF51735 13 256 4.26E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 255 2.5E-58 T 12-10-2018 AFR_04010 97d0f0802c88c0852627aef701d2f349 257 Gene3D G3DSA:3.40.50.720 2 257 2.1E-79 T 12-10-2018 AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04010 97d0f0802c88c0852627aef701d2f349 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_21045 49fe43ee4e73092f776c1fa43ea6560a 276 Gene3D G3DSA:3.10.310.10 6 272 2.1E-68 T 12-10-2018 AFR_21045 49fe43ee4e73092f776c1fa43ea6560a 276 PIRSF PIRSF016184 1 275 1.8E-62 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFR_21045 49fe43ee4e73092f776c1fa43ea6560a 276 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 272 2.4E-50 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFR_21045 49fe43ee4e73092f776c1fa43ea6560a 276 Pfam PF02567 Phenazine biosynthesis-like protein 6 273 3.1E-64 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFR_21045 49fe43ee4e73092f776c1fa43ea6560a 276 Gene3D G3DSA:3.10.310.10 116 270 2.1E-68 T 12-10-2018 AFR_21045 49fe43ee4e73092f776c1fa43ea6560a 276 SUPERFAMILY SSF54506 2 273 1.7E-57 T 12-10-2018 AFR_32140 4b41929b1b976413b6f520944c7901e5 390 SUPERFAMILY SSF52266 180 388 1.45E-39 T 12-10-2018 AFR_32140 4b41929b1b976413b6f520944c7901e5 390 Gene3D G3DSA:3.40.50.1110 171 387 4.1E-28 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_32140 4b41929b1b976413b6f520944c7901e5 390 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 183 378 6.5E-23 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_27630 c4632d69a57ecbdc071b7de596fb46bd 366 Gene3D G3DSA:3.40.50.2300 150 354 9.8E-110 T 12-10-2018 AFR_27630 c4632d69a57ecbdc071b7de596fb46bd 366 Gene3D G3DSA:3.40.50.2300 46 341 9.8E-110 T 12-10-2018 AFR_27630 c4632d69a57ecbdc071b7de596fb46bd 366 Pfam PF13407 Periplasmic binding protein domain 46 318 2.0E-57 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_27630 c4632d69a57ecbdc071b7de596fb46bd 366 SUPERFAMILY SSF53822 45 354 2.88E-55 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_34575 c64520ec283a1e0fde860d0200ec64e6 256 SMART SM00382 31 210 8.0E-21 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_34575 c64520ec283a1e0fde860d0200ec64e6 256 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_34575 c64520ec283a1e0fde860d0200ec64e6 256 SUPERFAMILY SSF52540 6 230 4.41E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34575 c64520ec283a1e0fde860d0200ec64e6 256 Gene3D G3DSA:3.40.50.300 2 229 7.6E-64 T 12-10-2018 AFR_34575 c64520ec283a1e0fde860d0200ec64e6 256 Pfam PF00005 ABC transporter 22 161 2.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 SUPERFAMILY SSF52266 27 228 6.06E-33 T 12-10-2018 AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 Pfam PF00652 Ricin-type beta-trefoil lectin domain 244 364 1.5E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 Gene3D G3DSA:3.40.50.1110 33 238 2.4E-69 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 SUPERFAMILY SSF50370 242 365 6.26E-38 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 Gene3D G3DSA:2.80.10.50 288 366 2.8E-24 T 12-10-2018 AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 Gene3D G3DSA:2.80.10.50 239 287 1.0E-11 T 12-10-2018 AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 42 218 5.1E-20 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_29170 e48f29de1e0b5cc953215b5ff6379f3d 367 SMART SM00458 242 367 1.7E-26 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_36385 fac5f471d2881cf85048437db93f6743 420 SUPERFAMILY SSF52413 307 413 3.01E-21 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFR_36385 fac5f471d2881cf85048437db93f6743 420 PIRSF PIRSF500136 1 420 3.9E-144 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 AFR_36385 fac5f471d2881cf85048437db93f6743 420 PIRSF PIRSF000124 3 419 3.7E-59 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_36385 fac5f471d2881cf85048437db93f6743 420 SUPERFAMILY SSF48179 200 298 7.82E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_36385 fac5f471d2881cf85048437db93f6743 420 Gene3D G3DSA:3.40.50.720 199 420 1.8E-62 T 12-10-2018 AFR_36385 fac5f471d2881cf85048437db93f6743 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 180 2.2E-36 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_36385 fac5f471d2881cf85048437db93f6743 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 412 1.1E-16 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_36385 fac5f471d2881cf85048437db93f6743 420 Gene3D G3DSA:3.40.50.720 1 197 5.5E-60 T 12-10-2018 AFR_36385 fac5f471d2881cf85048437db93f6743 420 SMART SM00984 319 414 5.1E-23 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_36385 fac5f471d2881cf85048437db93f6743 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 396 2.5E-125 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_36385 fac5f471d2881cf85048437db93f6743 420 SUPERFAMILY SSF51735 5 194 1.35E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36385 fac5f471d2881cf85048437db93f6743 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 200 292 4.1E-29 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_14090 fe36aca8e5eec7d750bf09222950d08c 79 Gene3D G3DSA:3.40.50.720 2 72 6.9E-13 T 12-10-2018 AFR_14090 fe36aca8e5eec7d750bf09222950d08c 79 SUPERFAMILY SSF51735 10 65 1.34E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_26170 26622cf3514c844de7ad51847c70c971 140 SMART SM00347 23 125 1.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_26170 26622cf3514c844de7ad51847c70c971 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 8.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_26170 26622cf3514c844de7ad51847c70c971 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 8.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_26170 26622cf3514c844de7ad51847c70c971 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 8.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_26170 26622cf3514c844de7ad51847c70c971 140 Gene3D G3DSA:1.10.10.10 2 135 1.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26170 26622cf3514c844de7ad51847c70c971 140 SUPERFAMILY SSF46785 3 136 3.6E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26170 26622cf3514c844de7ad51847c70c971 140 Pfam PF12802 MarR family 29 86 4.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_18005 c4231d09af331702616dad06d0f5cce8 360 SMART SM00633 87 355 1.0E-90 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18005 c4231d09af331702616dad06d0f5cce8 360 SUPERFAMILY SSF51445 43 355 2.18E-107 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_18005 c4231d09af331702616dad06d0f5cce8 360 PRINTS PR00134 Glycosyl hydrolase family 10 signature 118 130 2.1E-15 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18005 c4231d09af331702616dad06d0f5cce8 360 PRINTS PR00134 Glycosyl hydrolase family 10 signature 162 173 2.1E-15 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18005 c4231d09af331702616dad06d0f5cce8 360 PRINTS PR00134 Glycosyl hydrolase family 10 signature 206 217 2.1E-15 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18005 c4231d09af331702616dad06d0f5cce8 360 PRINTS PR00134 Glycosyl hydrolase family 10 signature 235 247 2.1E-15 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18005 c4231d09af331702616dad06d0f5cce8 360 Pfam PF00331 Glycosyl hydrolase family 10 44 353 3.1E-97 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18005 c4231d09af331702616dad06d0f5cce8 360 Gene3D G3DSA:3.20.20.80 27 357 9.2E-112 T 12-10-2018 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 SUPERFAMILY SSF53244 312 441 4.76E-31 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 SUPERFAMILY SSF53623 102 306 9.42E-42 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 Pfam PF08245 Mur ligase middle domain 107 290 3.5E-31 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 Pfam PF01225 Mur ligase family, catalytic domain 32 105 1.4E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 Gene3D G3DSA:3.40.1390.10 1 81 3.1E-16 T 12-10-2018 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 440 9.8E-101 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 395 3.3E-17 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 Gene3D G3DSA:3.90.190.20 310 444 1.1E-33 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 SUPERFAMILY SSF63418 1 96 3.27E-17 T 12-10-2018 IPR035911 MurE/MurF, N-terminal AFR_10845 72143836a2c37a49941db8df5fd5ed62 460 Gene3D G3DSA:3.40.1190.10 82 307 6.9E-55 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_41190 63dab21115248dac78b5e5b43d81ba5d 398 Pfam PF07690 Major Facilitator Superfamily 17 349 1.8E-35 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_41190 63dab21115248dac78b5e5b43d81ba5d 398 SUPERFAMILY SSF103473 5 386 1.19E-49 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_41190 63dab21115248dac78b5e5b43d81ba5d 398 Gene3D G3DSA:1.20.1250.20 2 386 7.5E-44 T 12-10-2018 AFR_28745 69f7cf57250f507cd7f07e5ee0972256 382 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_28745 69f7cf57250f507cd7f07e5ee0972256 382 Gene3D G3DSA:3.40.50.720 168 339 1.1E-119 T 12-10-2018 AFR_28745 69f7cf57250f507cd7f07e5ee0972256 382 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 3.6E-29 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_28745 69f7cf57250f507cd7f07e5ee0972256 382 SUPERFAMILY SSF51735 154 340 2.12E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_28745 69f7cf57250f507cd7f07e5ee0972256 382 Gene3D G3DSA:3.90.180.10 4 366 1.1E-119 T 12-10-2018 AFR_28745 69f7cf57250f507cd7f07e5ee0972256 382 SUPERFAMILY SSF50129 2 187 1.67E-57 T 12-10-2018 IPR011032 GroES-like superfamily AFR_28745 69f7cf57250f507cd7f07e5ee0972256 382 Pfam PF00107 Zinc-binding dehydrogenase 188 259 5.4E-9 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_31505 a6f39fa48728a04eca24fb1c859d0faa 437 Gene3D G3DSA:3.20.20.140 1 425 9.9E-139 T 12-10-2018 AFR_31505 a6f39fa48728a04eca24fb1c859d0faa 437 SUPERFAMILY SSF51338 1 425 1.23E-26 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_31505 a6f39fa48728a04eca24fb1c859d0faa 437 TIGRFAM TIGR03178 allantoinase: allantoinase 3 425 9.6E-170 T 12-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 AFR_31505 a6f39fa48728a04eca24fb1c859d0faa 437 Pfam PF01979 Amidohydrolase family 52 422 6.0E-28 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_31505 a6f39fa48728a04eca24fb1c859d0faa 437 SUPERFAMILY SSF51556 55 369 7.57E-95 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_30520 444170a714a05d75f7edf24da4967566 351 Gene3D G3DSA:3.40.430.10 143 350 1.1E-65 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_30520 444170a714a05d75f7edf24da4967566 351 Pfam PF01872 RibD C-terminal domain 148 340 3.4E-53 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_30520 444170a714a05d75f7edf24da4967566 351 SUPERFAMILY SSF53927 4 145 4.85E-41 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFR_30520 444170a714a05d75f7edf24da4967566 351 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 1.2E-16 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFR_30520 444170a714a05d75f7edf24da4967566 351 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 90 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFR_30520 444170a714a05d75f7edf24da4967566 351 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 345 1.0E-55 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 AFR_30520 444170a714a05d75f7edf24da4967566 351 PIRSF PIRSF006769 1 349 2.0E-120 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 AFR_30520 444170a714a05d75f7edf24da4967566 351 SUPERFAMILY SSF53597 146 343 2.94E-57 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_30520 444170a714a05d75f7edf24da4967566 351 Gene3D G3DSA:3.40.140.10 1 142 2.4E-39 T 12-10-2018 AFR_30520 444170a714a05d75f7edf24da4967566 351 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 342 2.2E-111 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 AFR_32500 04777e633c63be9143ea612c142363d7 216 SMART SM00382 29 211 9.0E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_32500 04777e633c63be9143ea612c142363d7 216 SUPERFAMILY SSF52540 15 210 5.08E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32500 04777e633c63be9143ea612c142363d7 216 Gene3D G3DSA:3.40.50.300 2 214 8.6E-56 T 12-10-2018 AFR_32500 04777e633c63be9143ea612c142363d7 216 Pfam PF00005 ABC transporter 20 164 1.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_32500 04777e633c63be9143ea612c142363d7 216 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 Pfam PF01580 FtsK/SpoIIIE family 804 1039 3.8E-51 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 Pfam PF01580 FtsK/SpoIIIE family 433 569 2.3E-25 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 SUPERFAMILY SSF52540 767 1014 2.02E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 SUPERFAMILY SSF52540 441 688 3.97E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 Gene3D G3DSA:3.40.50.300 771 1076 5.1E-87 T 12-10-2018 AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 Gene3D G3DSA:3.40.50.300 225 334 9.7E-6 T 12-10-2018 AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 SUPERFAMILY SSF52540 1073 1258 6.48E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 748 1314 3.7E-224 T 12-10-2018 IPR023837 EccCb-like, Actinobacteria AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 Gene3D G3DSA:3.40.50.300 1082 1317 3.9E-46 T 12-10-2018 AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 690 4.5E-261 T 12-10-2018 IPR023836 EccCa-like, Actinobacteria AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 SMART SM00382 467 646 0.0021 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 SMART SM00382 828 999 0.46 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02545 d1da189c4841f1725ecd53cc7600f937 1323 SMART SM00382 1110 1275 0.13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_42500 c21b4896ee3c02ebd9d3f4638b3d2aa8 321 Gene3D G3DSA:3.40.50.720 12 306 1.1E-91 T 12-10-2018 AFR_42500 c21b4896ee3c02ebd9d3f4638b3d2aa8 321 Gene3D G3DSA:3.90.25.10 198 319 1.1E-91 T 12-10-2018 AFR_42500 c21b4896ee3c02ebd9d3f4638b3d2aa8 321 Pfam PF16363 GDP-mannose 4,6 dehydratase 14 315 9.6E-45 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_42500 c21b4896ee3c02ebd9d3f4638b3d2aa8 321 SUPERFAMILY SSF51735 8 320 9.04E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_06950 1ed0267ba89b57af6543cda0804ae0b5 329 Gene3D G3DSA:1.10.10.10 1 64 1.1E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06950 1ed0267ba89b57af6543cda0804ae0b5 329 SUPERFAMILY SSF46785 3 55 1.39E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06950 1ed0267ba89b57af6543cda0804ae0b5 329 PIRSF PIRSF016838 1 56 0.003 T 12-10-2018 IPR028349 Protein PafC AFR_06950 1ed0267ba89b57af6543cda0804ae0b5 329 PIRSF PIRSF016838 70 327 3.0E-15 T 12-10-2018 IPR028349 Protein PafC AFR_06950 1ed0267ba89b57af6543cda0804ae0b5 329 Pfam PF13280 WYL domain 139 319 6.5E-42 T 12-10-2018 IPR026881 WYL domain AFR_06950 1ed0267ba89b57af6543cda0804ae0b5 329 Pfam PF08279 HTH domain 9 60 4.4E-16 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Pfam PF00009 Elongation factor Tu GTP binding domain 7 180 3.5E-50 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 SUPERFAMILY SSF52540 4 219 2.51E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Gene3D G3DSA:2.40.50.250 497 612 1.2E-118 T 12-10-2018 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Pfam PF00679 Elongation factor G C-terminus 411 493 7.8E-22 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Gene3D G3DSA:3.30.70.240 404 496 1.2E-118 T 12-10-2018 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Pfam PF03144 Elongation factor Tu domain 2 233 303 1.8E-10 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 SUPERFAMILY SSF50447 160 313 1.3E-29 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 SUPERFAMILY SSF54980 316 402 8.15E-11 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Gene3D G3DSA:3.40.50.300 5 212 1.0E-58 T 12-10-2018 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 612 3.9E-277 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 SMART SM00838 410 498 0.0077 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 161 6.5E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 SUPERFAMILY SSF54980 413 527 2.64E-28 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 PRINTS PR00315 GTP-binding elongation factor signature 53 61 3.0E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.0E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 PRINTS PR00315 GTP-binding elongation factor signature 9 22 3.0E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.0E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.0E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Gene3D G3DSA:2.40.30.10 214 313 9.1E-29 T 12-10-2018 AFR_10490 e42cf75605d56e77b0ede231544ab5f9 622 Gene3D G3DSA:3.30.70.870 321 604 1.2E-118 T 12-10-2018 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 493 5.2E-209 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 SUPERFAMILY SSF53067 251 494 3.52E-77 T 12-10-2018 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 SUPERFAMILY SSF53067 5 251 8.64E-88 T 12-10-2018 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 Gene3D G3DSA:3.30.420.40 250 496 3.3E-89 T 12-10-2018 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 Hamap MF_00186 Glycerol kinase [glpK]. 3 494 52.546 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 248 6.0E-72 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 447 7.2E-60 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 Gene3D G3DSA:3.30.420.40 3 249 4.7E-103 T 12-10-2018 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 359 379 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_27445 074724fa04ae854d7118d703a8638fd0 497 PIRSF PIRSF000538 3 497 1.0E-162 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_17145 659d870a8ff416db4127915e9582cec5 404 SUPERFAMILY SSF53067 82 386 2.35E-51 T 12-10-2018 AFR_17145 659d870a8ff416db4127915e9582cec5 404 Gene3D G3DSA:1.10.10.10 17 78 3.5E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17145 659d870a8ff416db4127915e9582cec5 404 Gene3D G3DSA:3.30.420.40 89 376 7.4E-80 T 12-10-2018 AFR_17145 659d870a8ff416db4127915e9582cec5 404 Gene3D G3DSA:3.30.420.40 207 367 7.4E-80 T 12-10-2018 AFR_17145 659d870a8ff416db4127915e9582cec5 404 Pfam PF00480 ROK family 85 382 5.3E-49 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_17145 659d870a8ff416db4127915e9582cec5 404 SUPERFAMILY SSF46785 18 78 1.63E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 SUPERFAMILY SSF51905 6 229 6.29E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 SUPERFAMILY SSF51905 150 382 4.02E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 Gene3D G3DSA:3.50.50.60 340 536 1.5E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 Gene3D G3DSA:3.50.50.60 4 312 1.0E-69 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 2.0E-5 T 12-10-2018 AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 2.0E-5 T 12-10-2018 AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.0E-5 T 12-10-2018 AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 SUPERFAMILY SSF51905 319 534 1.94E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17805 00b72eab5df21d309cf40ff617ef6f4d 536 Pfam PF00743 Flavin-binding monooxygenase-like 12 211 1.0E-19 T 12-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 SUPERFAMILY SSF55073 147 320 8.63E-20 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 SMART SM00448 18 131 1.6E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 SMART SM00267 137 322 1.3E-4 T 12-10-2018 IPR000160 GGDEF domain AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 SUPERFAMILY SSF52172 18 146 3.13E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 Gene3D G3DSA:3.40.50.2300 3 145 4.1E-39 T 12-10-2018 AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 Pfam PF00990 Diguanylate cyclase, GGDEF domain 146 231 4.6E-11 T 12-10-2018 IPR000160 GGDEF domain AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 Gene3D G3DSA:3.30.70.270 146 326 1.7E-22 T 12-10-2018 AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 Pfam PF00072 Response regulator receiver domain 20 131 2.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30525 1e76673c5fc71e0f2d5f4e334f877e39 341 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 155 293 4.6E-12 T 12-10-2018 IPR000160 GGDEF domain AFR_16010 bda05f3b428046d092c234e742f6c73e 310 Pfam PF00535 Glycosyl transferase family 2 10 127 2.7E-13 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_16010 bda05f3b428046d092c234e742f6c73e 310 Gene3D G3DSA:3.90.550.10 3 238 2.0E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16010 bda05f3b428046d092c234e742f6c73e 310 SUPERFAMILY SSF53448 7 259 1.69E-37 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 464 46.007 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 Pfam PF00156 Phosphoribosyl transferase domain 287 394 1.4E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 Pfam PF13522 Glutamine amidotransferase domain 85 218 8.7E-19 T 12-10-2018 AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 PIRSF PIRSF000485 19 477 2.6E-164 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 SUPERFAMILY SSF56235 23 277 1.54E-66 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 465 1.7E-159 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 Gene3D G3DSA:3.60.20.10 23 466 3.0E-153 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 Gene3D G3DSA:3.40.50.2020 283 447 3.0E-153 T 12-10-2018 AFR_00740 bcd3df4f0c74829cee3e17a5a185af09 536 SUPERFAMILY SSF53271 259 471 5.77E-68 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 ProSitePatterns PS01008 DnaA protein signature. 582 601 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 SUPERFAMILY SSF48295 519 624 2.88E-34 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 8 623 32.562 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 534 601 1.4E-29 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 Gene3D G3DSA:3.40.50.300 283 452 8.7E-51 T 12-10-2018 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 SMART SM00382 320 448 1.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 237 622 2.3E-150 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 Gene3D G3DSA:1.10.8.60 454 524 2.6E-25 T 12-10-2018 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 Gene3D G3DSA:1.10.1750.10 528 626 2.6E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 Gene3D G3DSA:3.30.300.180 5 84 1.2E-7 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 582 601 3.2E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 321 341 3.2E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 385 399 3.2E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 353 367 3.2E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 419 446 3.2E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 Pfam PF00308 Bacterial dnaA protein 288 505 1.2E-98 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 SMART SM00760 532 601 4.9E-37 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFR_00005 b7890d932ae4c245ecb3bee17655d797 626 SUPERFAMILY SSF52540 287 499 6.15E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 Gene3D G3DSA:2.60.40.10 630 715 5.5E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 115 126 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 SMART SM00060 382 452 0.022 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 SMART SM00060 548 619 0.38 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 SMART SM00060 464 536 0.034 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 SMART SM00060 631 706 2.1E-4 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 Pfam PF00082 Subtilase family 112 361 2.0E-40 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 158 168 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 311 321 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 Gene3D G3DSA:2.60.40.10 551 629 3.5E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 Gene3D G3DSA:2.60.40.10 385 462 2.0E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 Gene3D G3DSA:2.60.40.10 466 546 1.5E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 SUPERFAMILY SSF52743 84 370 1.96E-71 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 SUPERFAMILY SSF49265 384 551 5.5E-10 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 SUPERFAMILY SSF49265 548 712 3.83E-14 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 Gene3D G3DSA:3.40.50.200 54 375 3.0E-79 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 PRINTS PR00723 Subtilisin serine protease family (S8) signature 310 326 2.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 167 2.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_06745 4f22a86a57a32b96a8b14641375252d0 825 PRINTS PR00723 Subtilisin serine protease family (S8) signature 110 129 2.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 SUPERFAMILY SSF56112 16 241 2.66E-33 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 SUPERFAMILY SSF52540 258 516 1.55E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Pfam PF01590 GAF domain 1245 1368 9.5E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1400 1558 3.7E-48 T 12-10-2018 IPR000160 GGDEF domain AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 SUPERFAMILY SSF55073 1404 1560 7.61E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Gene3D G3DSA:1.10.510.10 70 247 1.9E-36 T 12-10-2018 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Pfam PF13191 AAA ATPase domain 265 444 9.5E-28 T 12-10-2018 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Gene3D G3DSA:3.30.450.40 1229 1386 1.9E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Pfam PF00069 Protein kinase domain 82 236 1.2E-19 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 SMART SM00065 1244 1378 5.3E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 SMART SM00267 1388 1562 7.4E-65 T 12-10-2018 IPR000160 GGDEF domain AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 SUPERFAMILY SSF55781 1231 1384 9.38E-23 T 12-10-2018 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Gene3D G3DSA:3.30.70.270 1387 1561 5.3E-57 T 12-10-2018 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1395 1560 9.4E-50 T 12-10-2018 IPR000160 GGDEF domain AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 Gene3D G3DSA:3.40.50.300 260 446 2.3E-5 T 12-10-2018 AFR_28480 5bf098c9323f1cbfebf1c4c67762ac02 1564 SMART SM00220 3 242 2.4E-12 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_11615 87e84d957a5ea6c2c973d8f3927d17e1 385 Pfam PF13692 Glycosyl transferases group 1 185 317 1.9E-20 T 12-10-2018 AFR_11615 87e84d957a5ea6c2c973d8f3927d17e1 385 Pfam PF13439 Glycosyltransferase Family 4 14 162 2.9E-19 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_11615 87e84d957a5ea6c2c973d8f3927d17e1 385 SUPERFAMILY SSF53756 2 357 1.33E-62 T 12-10-2018 AFR_11615 87e84d957a5ea6c2c973d8f3927d17e1 385 Gene3D G3DSA:3.40.50.2000 168 336 1.8E-32 T 12-10-2018 AFR_11615 87e84d957a5ea6c2c973d8f3927d17e1 385 Gene3D G3DSA:3.40.50.2000 1 167 7.5E-15 T 12-10-2018 AFR_26255 4aaefbc2059ed22e331d85be67f5eb59 188 Gene3D G3DSA:1.20.120.450 4 159 1.6E-29 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_26255 4aaefbc2059ed22e331d85be67f5eb59 188 SUPERFAMILY SSF109854 8 155 3.36E-35 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_26255 4aaefbc2059ed22e331d85be67f5eb59 188 Pfam PF04978 Protein of unknown function (DUF664) 10 156 2.1E-42 T 12-10-2018 IPR007061 Protein of unknown function DUF664 AFR_12915 72e6d0691f7cce63f5243656a5175b64 514 Gene3D G3DSA:1.20.1720.10 26 245 2.7E-43 T 12-10-2018 AFR_12915 72e6d0691f7cce63f5243656a5175b64 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 8.4E-12 T 12-10-2018 AFR_12915 72e6d0691f7cce63f5243656a5175b64 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 8.4E-12 T 12-10-2018 AFR_12915 72e6d0691f7cce63f5243656a5175b64 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 414 433 8.4E-12 T 12-10-2018 AFR_12915 72e6d0691f7cce63f5243656a5175b64 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 8.4E-12 T 12-10-2018 AFR_12915 72e6d0691f7cce63f5243656a5175b64 514 Pfam PF07690 Major Facilitator Superfamily 28 423 2.0E-41 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_12915 72e6d0691f7cce63f5243656a5175b64 514 SUPERFAMILY SSF103473 22 503 1.44E-63 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 407 516 3.7E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 SUPERFAMILY SSF47384 283 364 9.81E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Pfam PF00512 His Kinase A (phospho-acceptor) domain 299 364 3.0E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 SMART SM00387 406 518 5.6E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Gene3D G3DSA:1.20.1440.210 54 176 3.5E-9 T 12-10-2018 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Pfam PF05227 CHASE3 domain 49 174 1.0E-19 T 12-10-2018 IPR007891 CHASE3 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Gene3D G3DSA:3.30.565.10 369 519 1.0E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Pfam PF00672 HAMP domain 217 264 2.5E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Gene3D G3DSA:1.20.1480.50 178 276 1.5E-9 T 12-10-2018 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 Gene3D G3DSA:1.10.287.130 284 366 9.2E-15 T 12-10-2018 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 SUPERFAMILY SSF158472 217 265 2.75E-7 T 12-10-2018 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 3.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 515 3.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 496 3.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 SUPERFAMILY SSF55874 355 516 6.16E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 SMART SM00304 217 269 1.3E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_03990 5fc8e7ff8e1624c18d460cb34e4f7899 531 SMART SM00388 298 366 3.3E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_01640 b6cda854387a5131ec3acb45fcd97e8d 231 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 230 1.5E-54 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFR_01640 b6cda854387a5131ec3acb45fcd97e8d 231 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 230 32.854 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFR_01640 b6cda854387a5131ec3acb45fcd97e8d 231 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFR_01640 b6cda854387a5131ec3acb45fcd97e8d 231 SUPERFAMILY SSF53335 3 226 5.11E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_01640 b6cda854387a5131ec3acb45fcd97e8d 231 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 230 3.0E-64 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFR_01640 b6cda854387a5131ec3acb45fcd97e8d 231 Gene3D G3DSA:3.40.50.150 19 231 3.8E-55 T 12-10-2018 AFR_01640 b6cda854387a5131ec3acb45fcd97e8d 231 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFR_18145 de45892422b92bd2dbcfc657c9d23344 292 SUPERFAMILY SSF53474 2 280 1.08E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18145 de45892422b92bd2dbcfc657c9d23344 292 Gene3D G3DSA:3.40.50.1820 1 283 5.3E-68 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18145 de45892422b92bd2dbcfc657c9d23344 292 Pfam PF12146 Serine aminopeptidase, S33 32 270 5.3E-15 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFR_26940 04635992e61126564f989eed6643148d 165 SUPERFAMILY SSF88946 4 87 1.45E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_26940 04635992e61126564f989eed6643148d 165 SUPERFAMILY SSF88659 90 153 3.55E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_26940 04635992e61126564f989eed6643148d 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 152 5.8E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_26940 04635992e61126564f989eed6643148d 165 Gene3D G3DSA:1.10.10.10 75 155 1.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26940 04635992e61126564f989eed6643148d 165 Pfam PF04542 Sigma-70 region 2 16 74 5.1E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_26940 04635992e61126564f989eed6643148d 165 Pfam PF08281 Sigma-70, region 4 96 149 1.7E-18 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_26940 04635992e61126564f989eed6643148d 165 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 153 1.3E-48 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_26940 04635992e61126564f989eed6643148d 165 Gene3D G3DSA:1.10.1740.10 2 74 1.9E-10 T 12-10-2018 AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 Gene3D G3DSA:3.30.450.40 9 185 2.6E-19 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 SUPERFAMILY SSF55781 7 181 2.62E-16 T 12-10-2018 AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 Pfam PF00990 Diguanylate cyclase, GGDEF domain 196 346 1.2E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 Pfam PF13185 GAF domain 25 177 6.8E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 SUPERFAMILY SSF55073 201 347 1.8E-35 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 SMART SM00065 26 186 0.0085 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 Gene3D G3DSA:3.30.70.270 186 350 2.9E-44 T 12-10-2018 AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 SMART SM00267 185 351 6.7E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_19250 6a416db6ff081bdb14dcb182d9ee5301 351 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 193 347 4.8E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 Pfam PF02674 Colicin V production protein 2 143 3.8E-19 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 PRINTS PR00834 HtrA/DegQ protease family signature 321 338 6.3E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 PRINTS PR00834 HtrA/DegQ protease family signature 222 234 6.3E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 PRINTS PR00834 HtrA/DegQ protease family signature 343 360 6.3E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 PRINTS PR00834 HtrA/DegQ protease family signature 242 262 6.3E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 SUPERFAMILY SSF50494 204 369 1.87E-32 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 Gene3D G3DSA:2.40.10.10 274 375 1.5E-19 T 12-10-2018 AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 Pfam PF13365 Trypsin-like peptidase domain 214 350 2.1E-20 T 12-10-2018 AFR_41585 b78b50670cb786e6c0a99a9db17d0579 390 Gene3D G3DSA:2.40.10.10 181 270 1.7E-20 T 12-10-2018 AFR_00215 0da1a4c5f6217d802c7d4350960924b4 491 PIRSF PIRSF012666 1 491 5.4E-205 T 12-10-2018 IPR016602 Uncharacterised conserved protein UCP012666 AFR_00215 0da1a4c5f6217d802c7d4350960924b4 491 SUPERFAMILY SSF55931 37 467 3.92E-48 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_00215 0da1a4c5f6217d802c7d4350960924b4 491 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 186 244 1.1E-4 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_42645 d1c514a812b5aa0573695bd60ab06c96 549 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 44 142 7.9E-32 T 12-10-2018 IPR032093 Phospholipase D, N-terminal AFR_42645 d1c514a812b5aa0573695bd60ab06c96 549 SUPERFAMILY SSF56300 157 491 4.17E-30 T 12-10-2018 AFR_42645 d1c514a812b5aa0573695bd60ab06c96 549 Pfam PF09423 PhoD-like phosphatase 156 489 2.7E-110 T 12-10-2018 IPR018946 Alkaline phosphatase D-related AFR_42645 d1c514a812b5aa0573695bd60ab06c96 549 Gene3D G3DSA:3.60.21.70 148 546 2.4E-139 T 12-10-2018 IPR038607 PhoD-like superfamily AFR_42645 d1c514a812b5aa0573695bd60ab06c96 549 Gene3D G3DSA:2.60.40.380 36 145 7.5E-37 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 AFR_33790 ebaeea7d43e13e42884966b396a90e03 204 Pfam PF12146 Serine aminopeptidase, S33 67 133 8.7E-9 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFR_33790 ebaeea7d43e13e42884966b396a90e03 204 Gene3D G3DSA:3.40.50.1820 5 184 2.1E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33790 ebaeea7d43e13e42884966b396a90e03 204 SUPERFAMILY SSF53474 15 196 1.91E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11230 a67e20861beb43387e82025f2001da20 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11230 a67e20861beb43387e82025f2001da20 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 5.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11230 a67e20861beb43387e82025f2001da20 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 5.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11230 a67e20861beb43387e82025f2001da20 198 SUPERFAMILY SSF48498 89 196 2.97E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_11230 a67e20861beb43387e82025f2001da20 198 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 131 196 1.4E-6 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_11230 a67e20861beb43387e82025f2001da20 198 SUPERFAMILY SSF46689 13 80 4.89E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_11230 a67e20861beb43387e82025f2001da20 198 Gene3D G3DSA:1.10.357.10 15 196 2.0E-37 T 12-10-2018 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 Gene3D G3DSA:1.20.140.10 235 380 9.3E-55 T 12-10-2018 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.4E-47 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 SUPERFAMILY SSF47203 227 379 5.48E-58 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 118 4.6E-17 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 PIRSF PIRSF016578 2 110 0.3 T 12-10-2018 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 PIRSF PIRSF016578 130 378 1.3E-10 T 12-10-2018 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 216 3.4E-23 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 Gene3D G3DSA:2.40.110.10 122 234 6.1E-36 T 12-10-2018 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 Gene3D G3DSA:1.10.540.10 2 121 2.3E-22 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_21860 0957b2f316f7ab0b1a6cda57f48b3086 380 SUPERFAMILY SSF56645 7 241 9.03E-65 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_41660 53d1bfeab9afdfe4ab1e5b26bafabe63 379 Gene3D G3DSA:3.40.50.300 7 379 2.3E-78 T 12-10-2018 AFR_41660 53d1bfeab9afdfe4ab1e5b26bafabe63 379 Pfam PF02374 Anion-transporting ATPase 21 293 6.9E-25 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 AFR_41660 53d1bfeab9afdfe4ab1e5b26bafabe63 379 SUPERFAMILY SSF52540 20 295 2.54E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 SMART SM00862 144 216 5.1E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 SUPERFAMILY SSF46894 119 216 3.4E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 216 3.1E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 Pfam PF00072 Response regulator receiver domain 3 111 2.2E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 Gene3D G3DSA:1.10.10.10 118 217 8.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 SMART SM00448 1 111 1.2E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 SUPERFAMILY SSF52172 2 117 1.57E-25 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28235 a863c7b809a5a79a7338636c551b3aa8 217 Gene3D G3DSA:3.40.50.2300 1 117 4.7E-25 T 12-10-2018 AFR_24070 61292b377206982aaf264c381cb19b7a 737 Gene3D G3DSA:2.60.120.260 604 736 1.1E-33 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_24070 61292b377206982aaf264c381cb19b7a 737 SUPERFAMILY SSF49313 516 601 5.34E-7 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 AFR_24070 61292b377206982aaf264c381cb19b7a 737 SUPERFAMILY SSF51445 81 441 1.99E-49 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_24070 61292b377206982aaf264c381cb19b7a 737 Gene3D G3DSA:2.60.40.10 514 599 4.4E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_24070 61292b377206982aaf264c381cb19b7a 737 SMART SM00606 602 737 7.5E-21 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_24070 61292b377206982aaf264c381cb19b7a 737 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 82 257 4.3E-20 T 12-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_24070 61292b377206982aaf264c381cb19b7a 737 Gene3D G3DSA:3.20.20.80 78 442 2.5E-77 T 12-10-2018 AFR_24070 61292b377206982aaf264c381cb19b7a 737 Pfam PF03422 Carbohydrate binding module (family 6) 611 736 3.3E-21 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_24070 61292b377206982aaf264c381cb19b7a 737 SUPERFAMILY SSF49785 604 736 1.12E-27 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_12360 278616e6acce223a1e65fc3b1289925c 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 SUPERFAMILY SSF52172 1 132 2.13E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_12360 278616e6acce223a1e65fc3b1289925c 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 SUPERFAMILY SSF46894 154 217 2.14E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 SMART SM00448 2 116 1.7E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 Pfam PF00072 Response regulator receiver domain 4 117 4.7E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 SMART SM00421 155 212 1.3E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12360 278616e6acce223a1e65fc3b1289925c 221 Gene3D G3DSA:3.40.50.12740 2 218 1.0E-64 T 12-10-2018 AFR_07035 73cb81b4b74789f143a728aaaa91dc5c 543 Gene3D G3DSA:3.90.400.10 108 180 3.7E-149 T 12-10-2018 AFR_07035 73cb81b4b74789f143a728aaaa91dc5c 543 Pfam PF00128 Alpha amylase, catalytic domain 31 392 1.5E-74 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_07035 73cb81b4b74789f143a728aaaa91dc5c 543 SMART SM00642 16 420 8.6E-117 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_07035 73cb81b4b74789f143a728aaaa91dc5c 543 Gene3D G3DSA:3.20.20.80 8 475 3.7E-149 T 12-10-2018 AFR_07035 73cb81b4b74789f143a728aaaa91dc5c 543 SUPERFAMILY SSF51445 7 475 6.86E-123 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_08885 8ac335e2a768d80c6a19771eb144898d 194 Gene3D G3DSA:3.40.50.1950 9 168 1.0E-26 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFR_08885 8ac335e2a768d80c6a19771eb144898d 194 Pfam PF02441 Flavoprotein 12 151 1.7E-17 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFR_08885 8ac335e2a768d80c6a19771eb144898d 194 SUPERFAMILY SSF52507 10 149 2.22E-28 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFR_34115 6f315e29422a49188c21f1c13013b051 243 Gene3D G3DSA:1.10.10.10 143 242 7.6E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34115 6f315e29422a49188c21f1c13013b051 243 SMART SM00448 14 128 3.6E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34115 6f315e29422a49188c21f1c13013b051 243 SMART SM00862 163 238 3.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_34115 6f315e29422a49188c21f1c13013b051 243 SUPERFAMILY SSF46894 139 239 7.09E-28 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_34115 6f315e29422a49188c21f1c13013b051 243 SUPERFAMILY SSF52172 12 140 7.68E-39 T 12-10-2018 IPR011006 CheY-like superfamily AFR_34115 6f315e29422a49188c21f1c13013b051 243 Gene3D G3DSA:3.40.50.2300 12 142 5.6E-36 T 12-10-2018 AFR_34115 6f315e29422a49188c21f1c13013b051 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 238 4.8E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_34115 6f315e29422a49188c21f1c13013b051 243 Pfam PF00072 Response regulator receiver domain 16 129 1.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 SUPERFAMILY SSF46894 135 213 1.77E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 Pfam PF00072 Response regulator receiver domain 10 123 2.9E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 SMART SM00448 8 122 1.1E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 Gene3D G3DSA:3.40.50.12740 8 213 1.1E-66 T 12-10-2018 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.0E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 SMART SM00421 150 207 2.4E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20375 8898f1ccafc04530bbe97ec7180c9acb 216 SUPERFAMILY SSF52172 7 131 1.99E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_14400 284916e82cb7c40ebb316ef043fec121 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.9E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14400 284916e82cb7c40ebb316ef043fec121 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 9.9E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14400 284916e82cb7c40ebb316ef043fec121 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 9.9E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14400 284916e82cb7c40ebb316ef043fec121 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 9.9E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14400 284916e82cb7c40ebb316ef043fec121 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 7.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14400 284916e82cb7c40ebb316ef043fec121 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 7.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14400 284916e82cb7c40ebb316ef043fec121 238 SUPERFAMILY SSF51735 3 235 5.26E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14400 284916e82cb7c40ebb316ef043fec121 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 181 2.4E-4 T 12-10-2018 AFR_14400 284916e82cb7c40ebb316ef043fec121 238 Gene3D G3DSA:3.40.50.720 2 228 5.5E-51 T 12-10-2018 AFR_14400 284916e82cb7c40ebb316ef043fec121 238 Pfam PF00106 short chain dehydrogenase 3 186 7.6E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13725 79a4bdef4f9af5158590f892b67587d7 263 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 74 249 1.6E-19 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_13725 79a4bdef4f9af5158590f892b67587d7 263 SUPERFAMILY SSF52266 60 262 1.34E-31 T 12-10-2018 AFR_13725 79a4bdef4f9af5158590f892b67587d7 263 Gene3D G3DSA:3.40.50.1110 48 262 1.7E-30 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 Gene3D G3DSA:3.20.20.80 224 548 1.6E-79 T 12-10-2018 AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 SUPERFAMILY SSF51011 719 832 1.58E-5 T 12-10-2018 AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 SUPERFAMILY SSF49899 646 736 1.05E-8 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 475 826 1.7E-40 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 SMART SM00813 475 826 8.6E-50 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 Gene3D G3DSA:2.60.120.260 66 223 4.5E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 SUPERFAMILY SSF51445 202 553 1.3E-65 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 Gene3D G3DSA:2.60.120.560 597 755 1.2E-17 T 12-10-2018 AFR_25200 6b92d3677acfd6124e18be5213f9bc70 835 SUPERFAMILY SSF49785 63 225 3.74E-11 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_18295 9715aa314774313c12b5e2448e1c42dd 267 SUPERFAMILY SSF51658 3 245 1.2E-49 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_18295 9715aa314774313c12b5e2448e1c42dd 267 Pfam PF01261 Xylose isomerase-like TIM barrel 24 206 4.9E-26 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_18295 9715aa314774313c12b5e2448e1c42dd 267 Gene3D G3DSA:3.20.20.150 1 265 1.2E-63 T 12-10-2018 AFR_02865 52f715b8a1ab5cef8dea350a3b9d34ec 453 Gene3D G3DSA:3.40.190.10 59 413 5.9E-132 T 12-10-2018 AFR_02865 52f715b8a1ab5cef8dea350a3b9d34ec 453 SUPERFAMILY SSF53850 23 448 8.26E-70 T 12-10-2018 AFR_02865 52f715b8a1ab5cef8dea350a3b9d34ec 453 Gene3D G3DSA:3.40.190.10 157 440 5.9E-132 T 12-10-2018 AFR_02865 52f715b8a1ab5cef8dea350a3b9d34ec 453 Pfam PF01547 Bacterial extracellular solute-binding protein 52 346 3.7E-42 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_13150 07b157960b035511887f1dd9d6b96355 225 Gene3D G3DSA:3.40.50.2300 1 121 1.3E-36 T 12-10-2018 AFR_13150 07b157960b035511887f1dd9d6b96355 225 SUPERFAMILY SSF52172 2 181 6.26E-37 T 12-10-2018 IPR011006 CheY-like superfamily AFR_13150 07b157960b035511887f1dd9d6b96355 225 Gene3D G3DSA:1.10.10.10 123 224 2.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13150 07b157960b035511887f1dd9d6b96355 225 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13150 07b157960b035511887f1dd9d6b96355 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 1.3E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_13150 07b157960b035511887f1dd9d6b96355 225 SMART SM00448 1 112 4.9E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13150 07b157960b035511887f1dd9d6b96355 225 SMART SM00862 145 220 1.1E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_11830 4a8d50fc5721ab4ddefdec4b1568645e 100 Pfam PF08922 Domain of unknown function (DUF1905) 5 95 1.2E-26 T 12-10-2018 IPR015018 Protein of unknown function DUF1905 AFR_11830 4a8d50fc5721ab4ddefdec4b1568645e 100 Gene3D G3DSA:2.40.30.100 2 98 2.9E-6 T 12-10-2018 IPR037079 AF2212/PG0164-like superfamily AFR_11830 4a8d50fc5721ab4ddefdec4b1568645e 100 SUPERFAMILY SSF141694 2 96 1.41E-17 T 12-10-2018 AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 Pfam PF01374 Glycosyl hydrolase family 46 194 399 8.1E-95 T 12-10-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 Pfam PF00652 Ricin-type beta-trefoil lectin domain 38 158 2.0E-26 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 SUPERFAMILY SSF50370 42 160 3.9E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 Gene3D G3DSA:2.80.10.50 30 163 1.6E-40 T 12-10-2018 AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 SUPERFAMILY SSF53955 181 410 2.81E-83 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 SMART SM00458 37 161 1.4E-25 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 Gene3D G3DSA:1.20.141.10 189 408 1.2E-92 T 12-10-2018 AFR_41225 ab47ff8ee4dd6674c482a10890b522a1 411 Gene3D G3DSA:3.30.386.10 205 299 1.2E-92 T 12-10-2018 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 AFR_40215 c46c8876bb5167d513e837bca6e800e2 352 Pfam PF01553 Acyltransferase 126 255 3.3E-16 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_40215 c46c8876bb5167d513e837bca6e800e2 352 SMART SM00563 139 258 8.6E-17 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_40215 c46c8876bb5167d513e837bca6e800e2 352 PIRSF PIRSF016753 63 351 8.4E-92 T 12-10-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted AFR_40215 c46c8876bb5167d513e837bca6e800e2 352 SUPERFAMILY SSF69593 112 343 5.36E-32 T 12-10-2018 AFR_10470 14dfe535667a5e37696034ba3a248085 129 SUPERFAMILY SSF54427 5 128 1.7E-29 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_10470 14dfe535667a5e37696034ba3a248085 129 Gene3D G3DSA:3.10.450.50 4 128 7.7E-38 T 12-10-2018 AFR_10470 14dfe535667a5e37696034ba3a248085 129 Pfam PF07366 SnoaL-like polyketide cyclase 10 128 2.6E-31 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 AFR_19290 825fe04bf49176e978c68072196f7e5d 267 Gene3D G3DSA:3.40.1080.10 5 264 5.6E-64 T 12-10-2018 AFR_19290 825fe04bf49176e978c68072196f7e5d 267 Gene3D G3DSA:3.30.30.40 119 155 5.6E-64 T 12-10-2018 AFR_19290 825fe04bf49176e978c68072196f7e5d 267 SMART SM00882 5 225 9.3E-44 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFR_19290 825fe04bf49176e978c68072196f7e5d 267 SUPERFAMILY SSF100950 4 264 2.81E-74 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_19290 825fe04bf49176e978c68072196f7e5d 267 Pfam PF01144 Coenzyme A transferase 7 222 1.1E-25 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFR_41460 8656450bc1aa4ec61e7b678acbd6b40d 175 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 137 4.5E-35 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFR_41460 8656450bc1aa4ec61e7b678acbd6b40d 175 SUPERFAMILY SSF55083 1 147 2.22E-38 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFR_41460 8656450bc1aa4ec61e7b678acbd6b40d 175 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 87 98 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFR_41460 8656450bc1aa4ec61e7b678acbd6b40d 175 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 137 1.4E-32 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFR_41460 8656450bc1aa4ec61e7b678acbd6b40d 175 Gene3D G3DSA:3.30.70.560 1 160 2.7E-41 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFR_19835 4f08973fa10cd9f5e2e0291a3d623377 287 SUPERFAMILY SSF53474 35 271 1.39E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19835 4f08973fa10cd9f5e2e0291a3d623377 287 Pfam PF12695 Alpha/beta hydrolase family 146 214 2.3E-6 T 12-10-2018 IPR029059 Alpha/beta hydrolase fold-5 AFR_19835 4f08973fa10cd9f5e2e0291a3d623377 287 Gene3D G3DSA:3.40.50.1820 24 287 1.9E-78 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 292 477 5.2E-38 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 SUPERFAMILY SSF53067 285 524 1.42E-56 T 12-10-2018 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 Gene3D G3DSA:3.30.420.40 5 282 1.1E-63 T 12-10-2018 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 Hamap MF_00520 Ribulokinase [araB]. 7 535 44.715 T 12-10-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 9 525 5.0E-233 T 12-10-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 Gene3D G3DSA:3.30.420.40 285 538 1.1E-70 T 12-10-2018 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 PIRSF PIRSF000538 7 523 2.1E-57 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 9 279 8.1E-11 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFR_25550 47f4fae0f822a43838dd6940a9bc3b96 544 SUPERFAMILY SSF53067 9 282 3.08E-36 T 12-10-2018 AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 SUPERFAMILY SSF51735 7 247 9.03E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.7E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 7.5E-5 T 12-10-2018 AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 244 2.3E-63 T 12-10-2018 AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 Gene3D G3DSA:3.40.50.720 1 247 2.2E-86 T 12-10-2018 AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11915 19cc3bba8110c93d78177b2a7d045db3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Gene3D G3DSA:2.60.120.260 866 993 1.7E-35 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Gene3D G3DSA:2.60.40.1180 627 707 4.4E-14 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Gene3D G3DSA:3.20.20.80 262 626 6.2E-52 T 12-10-2018 AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 SUPERFAMILY SSF49785 868 991 3.74E-22 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 SUPERFAMILY SSF51011 623 706 3.31E-12 T 12-10-2018 AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 SUPERFAMILY SSF74650 36 259 9.73E-18 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Pfam PF03422 Carbohydrate binding module (family 6) 872 991 5.6E-11 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Gene3D G3DSA:2.60.40.1180 708 818 6.9E-21 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Gene3D G3DSA:2.60.40.1760 33 244 2.4E-25 T 12-10-2018 AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 SUPERFAMILY SSF51445 264 622 3.72E-31 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Pfam PF01055 Glycosyl hydrolases family 31 254 711 1.1E-81 T 12-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 AFR_34175 5836a745ca5c70a8bb0b1bfe7497b1e3 993 Pfam PF17137 Domain of unknown function (DUF5110) 727 796 9.8E-16 T 12-10-2018 IPR033403 Domain of unknown function DUF5110 AFR_42485 4a706fbc93b2448829c945bb05acbc25 176 SUPERFAMILY SSF50475 22 174 7.29E-19 T 12-10-2018 AFR_42485 4a706fbc93b2448829c945bb05acbc25 176 Gene3D G3DSA:2.30.110.10 7 176 2.0E-21 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_42485 4a706fbc93b2448829c945bb05acbc25 176 SMART SM00903 30 173 1.2E-14 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AFR_42485 4a706fbc93b2448829c945bb05acbc25 176 Pfam PF01613 Flavin reductase like domain 31 174 1.8E-15 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AFR_38285 9db896d835eeb87089e25c177fb1d9ff 282 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 11 122 3.6E-8 T 12-10-2018 IPR018697 Protein of unknown function DUF2199 AFR_08995 476159792e60a027e970a629f8afd248 204 SUPERFAMILY SSF142695 21 176 8.76E-52 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_08995 476159792e60a027e970a629f8afd248 204 Pfam PF00925 GTP cyclohydrolase II 21 174 5.8E-57 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_08995 476159792e60a027e970a629f8afd248 204 Gene3D G3DSA:3.40.50.10990 7 178 1.2E-61 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_38045 8fad72732cb3daffe32632f7354f184d 231 SUPERFAMILY SSF46785 7 79 6.82E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_38045 8fad72732cb3daffe32632f7354f184d 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.9E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_38045 8fad72732cb3daffe32632f7354f184d 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.9E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_38045 8fad72732cb3daffe32632f7354f184d 231 Gene3D G3DSA:1.10.10.10 4 83 1.8E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38045 8fad72732cb3daffe32632f7354f184d 231 SMART SM00345 14 75 1.3E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_38045 8fad72732cb3daffe32632f7354f184d 231 SUPERFAMILY SSF48008 102 226 3.92E-19 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_38045 8fad72732cb3daffe32632f7354f184d 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 69 2.1E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_38045 8fad72732cb3daffe32632f7354f184d 231 Pfam PF07729 FCD domain 104 223 3.6E-17 T 12-10-2018 IPR011711 GntR, C-terminal AFR_38045 8fad72732cb3daffe32632f7354f184d 231 Gene3D G3DSA:1.20.120.530 84 229 1.6E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_38045 8fad72732cb3daffe32632f7354f184d 231 SMART SM00895 104 224 1.0E-16 T 12-10-2018 IPR011711 GntR, C-terminal AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 SUPERFAMILY SSF56176 1 140 1.8E-27 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 Gene3D G3DSA:3.90.78.10 186 305 1.5E-34 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 Pfam PF01565 FAD binding domain 1 106 1.7E-14 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 SUPERFAMILY SSF56194 166 303 7.46E-31 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 168 301 4.6E-35 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 2 297 3.1E-44 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 Gene3D G3DSA:3.30.465.10 28 180 9.0E-46 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_40615 483882a99ca891f5bf567cae00b7d6fa 305 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 305 66.347 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 SUPERFAMILY SSF51445 133 573 9.39E-129 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 SUPERFAMILY SSF81296 5 147 2.24E-45 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 SMART SM00642 132 566 3.3E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 Gene3D G3DSA:2.60.40.10 1 136 6.9E-48 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 Gene3D G3DSA:2.60.40.1180 592 701 3.1E-16 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 Pfam PF00128 Alpha amylase, catalytic domain 189 530 1.7E-14 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 3.0E-21 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 699 2.8E-303 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 Gene3D G3DSA:3.20.20.80 138 580 1.6E-181 T 12-10-2018 AFR_31595 5ec4e1ab93d2f67ab1a6652e80e4125f 703 SUPERFAMILY SSF51011 592 699 2.45E-23 T 12-10-2018 AFR_10560 5dca64f36bb73c2131b5b573d6645c72 326 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 104 1.3E-28 T 12-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain AFR_10560 5dca64f36bb73c2131b5b573d6645c72 326 Pfam PF14527 WhiA LAGLIDADG-like domain 128 218 6.0E-25 T 12-10-2018 IPR039518 WhiA, LAGLIDADG-like domain AFR_10560 5dca64f36bb73c2131b5b573d6645c72 326 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 30.359 T 12-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 AFR_10560 5dca64f36bb73c2131b5b573d6645c72 326 Gene3D G3DSA:1.10.10.10 216 307 7.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10560 5dca64f36bb73c2131b5b573d6645c72 326 Gene3D G3DSA:3.10.28.10 1 214 2.0E-24 T 12-10-2018 IPR027434 Homing endonuclease AFR_10560 5dca64f36bb73c2131b5b573d6645c72 326 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.7E-18 T 12-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal AFR_10560 5dca64f36bb73c2131b5b573d6645c72 326 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 2.2E-104 T 12-10-2018 IPR033981 Sporulation regulator WhiA-like AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 SUPERFAMILY SSF51445 43 345 3.29E-109 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 115 127 3.3E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 232 244 3.3E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 202 213 3.3E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 PRINTS PR00134 Glycosyl hydrolase family 10 signature 157 168 3.3E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 SMART SM00637 369 459 2.4E-31 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 Pfam PF00553 Cellulose binding domain 373 458 2.8E-20 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 Gene3D G3DSA:2.60.40.290 364 462 2.4E-24 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 Pfam PF00331 Glycosyl hydrolase family 10 44 338 1.4E-109 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 Gene3D G3DSA:3.20.20.80 38 350 4.6E-122 T 12-10-2018 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 266 276 - T 12-10-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 SUPERFAMILY SSF49384 364 459 2.02E-24 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_18030 34162f2c4719b170de043b38c73a5d8c 463 SMART SM00633 84 340 6.0E-134 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17180 83a58c79016d4f70a237a358485f3a3a 312 SUPERFAMILY SSF51445 64 286 5.52E-8 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_17180 83a58c79016d4f70a237a358485f3a3a 312 Gene3D G3DSA:3.20.20.80 34 309 8.1E-9 T 12-10-2018 AFR_01540 e53dfa42e7d71e962199cb18ebb3da43 288 SUPERFAMILY SSF52540 8 217 5.53E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01540 e53dfa42e7d71e962199cb18ebb3da43 288 Pfam PF00005 ABC transporter 20 155 3.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01540 e53dfa42e7d71e962199cb18ebb3da43 288 SMART SM00382 28 204 2.0E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01540 e53dfa42e7d71e962199cb18ebb3da43 288 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_01540 e53dfa42e7d71e962199cb18ebb3da43 288 Gene3D G3DSA:3.40.50.300 3 224 2.1E-59 T 12-10-2018 AFR_20950 2aa1ce430a8f8101d164a9ca52531548 340 SUPERFAMILY SSF52540 6 239 3.17E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20950 2aa1ce430a8f8101d164a9ca52531548 340 SUPERFAMILY SSF50331 237 332 1.48E-11 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_20950 2aa1ce430a8f8101d164a9ca52531548 340 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_20950 2aa1ce430a8f8101d164a9ca52531548 340 SMART SM00382 30 210 4.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20950 2aa1ce430a8f8101d164a9ca52531548 340 Pfam PF08402 TOBE domain 270 333 1.9E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFR_20950 2aa1ce430a8f8101d164a9ca52531548 340 Pfam PF00005 ABC transporter 21 160 4.8E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20950 2aa1ce430a8f8101d164a9ca52531548 340 Gene3D G3DSA:3.40.50.300 5 246 3.5E-75 T 12-10-2018 AFR_02950 e08841618953034b6356196862df52bc 385 SUPERFAMILY SSF82171 128 363 5.1E-20 T 12-10-2018 AFR_02950 e08841618953034b6356196862df52bc 385 Pfam PF07676 WD40-like Beta Propeller Repeat 198 222 0.0019 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_02950 e08841618953034b6356196862df52bc 385 Pfam PF07676 WD40-like Beta Propeller Repeat 158 176 0.13 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_02950 e08841618953034b6356196862df52bc 385 Gene3D G3DSA:2.120.10.30 123 374 2.4E-18 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_28945 a879302263606d4fce6505c80c84582a 145 Pfam PF15956 Domain of unknown function (DUF4760) 14 114 3.5E-7 T 12-10-2018 IPR031876 Protein of unknown function DUF4760 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Gene3D G3DSA:3.30.300.20 258 337 4.5E-27 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 76 322 5.8E-97 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Pfam PF13184 NusA-like KH domain 210 278 1.0E-24 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 SUPERFAMILY SSF54814 260 324 6.47E-15 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 SMART SM00322 282 338 1.3 T 12-10-2018 IPR004087 K Homology domain GO:0003676 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 SMART SM00322 210 269 1.7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Gene3D G3DSA:2.40.50.140 105 178 3.4E-27 T 12-10-2018 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Pfam PF08529 NusA N-terminal domain 6 60 6.7E-10 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Pfam PF08529 NusA N-terminal domain 66 99 1.9E-7 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Gene3D G3DSA:3.30.1480.10 1 99 1.6E-35 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 333 25.561 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 SUPERFAMILY SSF54814 180 258 1.44E-27 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 Gene3D G3DSA:3.30.300.20 179 257 1.7E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 SUPERFAMILY SSF69705 2 98 9.55E-30 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 AFR_35985 48875720e7bbdd4124c2c3a80d986543 338 SUPERFAMILY SSF50249 110 179 2.57E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 SUPERFAMILY SSF52743 33 300 2.09E-45 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 Pfam PF00082 Subtilase family 53 279 2.6E-15 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 SUPERFAMILY SSF52743 322 571 4.19E-20 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 Gene3D G3DSA:3.40.50.200 21 305 1.4E-50 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 Gene3D G3DSA:3.40.50.200 308 575 7.7E-24 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 PRINTS PR00723 Subtilisin serine protease family (S8) signature 53 72 1.3E-7 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 PRINTS PR00723 Subtilisin serine protease family (S8) signature 88 101 1.3E-7 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_23195 ab4d229e2846f4a1f8829c8383223205 645 PRINTS PR00723 Subtilisin serine protease family (S8) signature 245 261 1.3E-7 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_02880 2bacbad9a8e602635b21cc878860083e 329 SUPERFAMILY SSF51735 138 299 3.16E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_02880 2bacbad9a8e602635b21cc878860083e 329 Gene3D G3DSA:3.90.180.10 14 309 2.6E-96 T 12-10-2018 AFR_02880 2bacbad9a8e602635b21cc878860083e 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_02880 2bacbad9a8e602635b21cc878860083e 329 SUPERFAMILY SSF50129 2 169 3.65E-49 T 12-10-2018 IPR011032 GroES-like superfamily AFR_02880 2bacbad9a8e602635b21cc878860083e 329 SMART SM00829 10 326 7.1E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_02880 2bacbad9a8e602635b21cc878860083e 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 130 3.1E-32 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_02880 2bacbad9a8e602635b21cc878860083e 329 Pfam PF00107 Zinc-binding dehydrogenase 171 280 1.2E-17 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_02880 2bacbad9a8e602635b21cc878860083e 329 Gene3D G3DSA:3.40.50.720 148 276 2.6E-96 T 12-10-2018 AFR_41295 7c02971f29c9c8dda6f20b5874f92d80 353 SUPERFAMILY SSF53901 7 351 2.04E-48 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_41295 7c02971f29c9c8dda6f20b5874f92d80 353 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 225 351 2.5E-23 T 12-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal AFR_41295 7c02971f29c9c8dda6f20b5874f92d80 353 Gene3D G3DSA:3.40.47.10 213 352 1.0E-44 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_41295 7c02971f29c9c8dda6f20b5874f92d80 353 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 3 203 9.7E-21 T 12-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal AFR_41295 7c02971f29c9c8dda6f20b5874f92d80 353 PIRSF PIRSF000451 2 353 3.6E-97 T 12-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 AFR_41295 7c02971f29c9c8dda6f20b5874f92d80 353 Gene3D G3DSA:3.40.47.10 1 211 3.6E-54 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_09365 840d1a9a2a4e7d10a7b336ab7435a094 124 Gene3D G3DSA:2.60.300.12 20 124 1.0E-29 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFR_09365 840d1a9a2a4e7d10a7b336ab7435a094 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 22 121 4.8E-18 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFR_09365 840d1a9a2a4e7d10a7b336ab7435a094 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 124 3.4E-35 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFR_09365 840d1a9a2a4e7d10a7b336ab7435a094 124 SUPERFAMILY SSF89360 20 114 5.1E-27 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFR_09365 840d1a9a2a4e7d10a7b336ab7435a094 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 106 123 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 AFR_27100 d8da713b6b4ea24fcee207392161f709 591 SMART SM00642 54 456 9.8E-117 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27100 d8da713b6b4ea24fcee207392161f709 591 Gene3D G3DSA:3.90.400.10 144 213 9.8E-227 T 12-10-2018 AFR_27100 d8da713b6b4ea24fcee207392161f709 591 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 46 584 1.8E-286 T 12-10-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622|MetaCyc: PWY-7900 AFR_27100 d8da713b6b4ea24fcee207392161f709 591 Pfam PF16657 Maltogenic Amylase, C-terminal domain 504 581 1.9E-25 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal AFR_27100 d8da713b6b4ea24fcee207392161f709 591 Gene3D G3DSA:3.20.20.80 45 498 9.8E-227 T 12-10-2018 AFR_27100 d8da713b6b4ea24fcee207392161f709 591 SUPERFAMILY SSF51011 509 584 4.89E-17 T 12-10-2018 AFR_27100 d8da713b6b4ea24fcee207392161f709 591 SUPERFAMILY SSF51445 57 504 6.94E-132 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27100 d8da713b6b4ea24fcee207392161f709 591 Pfam PF00128 Alpha amylase, catalytic domain 69 425 1.4E-76 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27100 d8da713b6b4ea24fcee207392161f709 591 Gene3D G3DSA:2.60.40.1180 504 591 1.8E-35 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 SUPERFAMILY SSF55874 187 341 1.31E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 Gene3D G3DSA:1.10.287.130 74 187 4.2E-25 T 12-10-2018 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 Pfam PF00672 HAMP domain 71 119 1.4E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 338 4.7E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 265 279 4.7E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 319 4.7E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 Pfam PF00512 His Kinase A (phospho-acceptor) domain 125 184 1.7E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 231 339 1.0E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 SMART SM00388 124 188 3.5E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 SMART SM00387 227 341 1.7E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 SUPERFAMILY SSF158472 72 121 4.05E-8 T 12-10-2018 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 Gene3D G3DSA:3.30.565.10 188 344 1.8E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 SUPERFAMILY SSF47384 107 184 2.75E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_19475 9082e9dc2b95e5ad8d9e24cdc154d367 351 SMART SM00304 70 123 3.8E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_25990 88efa489c5f688aacc7eeb786c1b842d 440 SUPERFAMILY SSF51905 171 395 7.78E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25990 88efa489c5f688aacc7eeb786c1b842d 440 SUPERFAMILY SSF51905 8 238 2.27E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25990 88efa489c5f688aacc7eeb786c1b842d 440 TIGRFAM TIGR04046 MSMEG_0569_nitr: flavin-dependent oxidoreductase, MSMEG_0569 family 8 405 4.4E-194 T 12-10-2018 IPR024000 Conserved hypothetical protein CHP04046, FMN-dependent AFR_25990 88efa489c5f688aacc7eeb786c1b842d 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.9E-6 T 12-10-2018 AFR_25990 88efa489c5f688aacc7eeb786c1b842d 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 1.9E-6 T 12-10-2018 AFR_25990 88efa489c5f688aacc7eeb786c1b842d 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 138 1.9E-6 T 12-10-2018 AFR_25990 88efa489c5f688aacc7eeb786c1b842d 440 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 207 1.7E-21 T 12-10-2018 AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 SMART SM00450 4 128 4.9E-17 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 SMART SM00450 145 264 1.1E-12 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 Gene3D G3DSA:3.40.250.10 1 143 3.3E-38 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 SUPERFAMILY SSF52821 156 268 1.27E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 SUPERFAMILY SSF52821 3 134 2.88E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 Pfam PF00581 Rhodanese-like domain 158 260 1.5E-8 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 Pfam PF00581 Rhodanese-like domain 9 123 1.6E-11 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 Gene3D G3DSA:3.40.250.10 152 267 9.8E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_04390 3bfbc670a5e78d97875718ee96573ffa 269 ProSitePatterns PS00380 Rhodanese signature 1. 36 47 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFR_09660 50b86b934cd7bac2dcfe74e6e70ed65f 189 Gene3D G3DSA:1.10.357.10 1 186 4.4E-41 T 12-10-2018 AFR_09660 50b86b934cd7bac2dcfe74e6e70ed65f 189 SUPERFAMILY SSF48498 80 180 3.25E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_09660 50b86b934cd7bac2dcfe74e6e70ed65f 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 5.2E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09660 50b86b934cd7bac2dcfe74e6e70ed65f 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09660 50b86b934cd7bac2dcfe74e6e70ed65f 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09660 50b86b934cd7bac2dcfe74e6e70ed65f 189 SUPERFAMILY SSF46689 3 84 3.64E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_36915 44d9a3e30f4d3a0a3c45bd4266ff8ac0 295 SUPERFAMILY SSF161098 22 294 8.11E-56 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36915 44d9a3e30f4d3a0a3c45bd4266ff8ac0 295 Gene3D G3DSA:1.10.3720.10 18 286 2.6E-50 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36915 44d9a3e30f4d3a0a3c45bd4266ff8ac0 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 279 4.9E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_41860 94fd2d4fec5b881ec6f8809c6478d479 408 Pfam PF02040 Arsenical pump membrane protein 5 396 5.4E-30 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFR_41860 94fd2d4fec5b881ec6f8809c6478d479 408 PRINTS PR00758 Arsenical pump membrane protein signature 375 399 1.3E-12 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFR_41860 94fd2d4fec5b881ec6f8809c6478d479 408 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 1.3E-12 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFR_41860 94fd2d4fec5b881ec6f8809c6478d479 408 PRINTS PR00758 Arsenical pump membrane protein signature 342 367 1.3E-12 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 Gene3D G3DSA:1.10.260.40 1 59 1.8E-21 T 12-10-2018 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 2.4E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 Gene3D G3DSA:3.40.50.2300 80 318 3.2E-61 T 12-10-2018 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 SUPERFAMILY SSF53822 78 339 4.91E-52 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 12-10-2018 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 Gene3D G3DSA:3.40.50.2300 169 296 3.2E-61 T 12-10-2018 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 SMART SM00354 3 73 2.0E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 SUPERFAMILY SSF47413 2 58 4.5E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_34740 7aacb84da40be5da643467faa5a0ad8d 341 Pfam PF13377 Periplasmic binding protein-like domain 177 335 7.1E-35 T 12-10-2018 AFR_09300 ad6b9cf6255de2c31820ce31ceb380ef 332 SUPERFAMILY SSF51430 1 315 1.57E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_09300 ad6b9cf6255de2c31820ce31ceb380ef 332 Pfam PF00248 Aldo/keto reductase family 15 313 1.0E-71 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_09300 ad6b9cf6255de2c31820ce31ceb380ef 332 Gene3D G3DSA:3.20.20.100 1 327 1.9E-109 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_09300 ad6b9cf6255de2c31820ce31ceb380ef 332 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 203 209 1.2E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 AFR_09300 ad6b9cf6255de2c31820ce31ceb380ef 332 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 270 283 1.2E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 AFR_09300 ad6b9cf6255de2c31820ce31ceb380ef 332 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 257 269 1.2E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 AFR_09300 ad6b9cf6255de2c31820ce31ceb380ef 332 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 1.2E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 AFR_30690 f7ba1a5747fef92cc47abed5dc84405b 403 Pfam PF07690 Major Facilitator Superfamily 27 367 3.2E-50 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_30690 f7ba1a5747fef92cc47abed5dc84405b 403 SUPERFAMILY SSF103473 14 401 9.68E-68 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_30690 f7ba1a5747fef92cc47abed5dc84405b 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 21 398 8.1E-92 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 AFR_30690 f7ba1a5747fef92cc47abed5dc84405b 403 Gene3D G3DSA:1.20.1720.10 21 399 9.7E-105 T 12-10-2018 AFR_17260 53dde06fa8ea39b7c48275f02b22d819 448 Pfam PF03069 Acetamidase/Formamidase family 145 179 1.9E-5 T 12-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 AFR_17260 53dde06fa8ea39b7c48275f02b22d819 448 Pfam PF03069 Acetamidase/Formamidase family 283 434 2.8E-20 T 12-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 AFR_17260 53dde06fa8ea39b7c48275f02b22d819 448 Gene3D G3DSA:3.10.28.20 361 448 1.9E-14 T 12-10-2018 AFR_17260 53dde06fa8ea39b7c48275f02b22d819 448 SUPERFAMILY SSF141130 68 448 2.35E-70 T 12-10-2018 AFR_17260 53dde06fa8ea39b7c48275f02b22d819 448 Gene3D G3DSA:2.60.120.580 255 351 7.5E-26 T 12-10-2018 AFR_17260 53dde06fa8ea39b7c48275f02b22d819 448 Gene3D G3DSA:2.60.120.580 64 219 9.5E-10 T 12-10-2018 AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 Pfam PF01022 Bacterial regulatory protein, arsR family 22 65 3.2E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 Gene3D G3DSA:1.10.10.10 3 98 1.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 SMART SM00418 14 92 4.3E-26 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 SUPERFAMILY SSF46785 6 92 5.45E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 2.5E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 2.5E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 2.5E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_08075 48f22e4bb794cac480c9d0849cba55cb 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 2.5E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_41705 fd81b14f0e7bb38405f952ef2e4d7ae4 159 Pfam PF00156 Phosphoribosyl transferase domain 45 140 2.7E-10 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFR_41705 fd81b14f0e7bb38405f952ef2e4d7ae4 159 Gene3D G3DSA:3.40.50.2020 2 159 3.6E-42 T 12-10-2018 AFR_41705 fd81b14f0e7bb38405f952ef2e4d7ae4 159 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 5 157 8.8E-32 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_41705 fd81b14f0e7bb38405f952ef2e4d7ae4 159 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 159 21.665 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_41705 fd81b14f0e7bb38405f952ef2e4d7ae4 159 SUPERFAMILY SSF53271 4 157 1.84E-34 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 Gene3D G3DSA:3.40.50.150 203 504 1.5E-55 T 12-10-2018 AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 SUPERFAMILY SSF53335 197 504 3.14E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 487 504 1.3E-22 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 315 325 1.3E-22 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 449 1.3E-22 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 282 296 1.3E-22 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 383 395 1.3E-22 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 Pfam PF01029 NusB family 58 179 7.3E-25 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 Pfam PF01189 16S rRNA methyltransferase RsmB/F 310 503 7.0E-44 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 Gene3D G3DSA:1.10.940.10 55 194 1.0E-37 T 12-10-2018 IPR035926 NusB-like superfamily AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 382 393 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 AFR_30545 8f4cabb38c0adf7ac24bcbd6bf488c9a 506 SUPERFAMILY SSF48013 58 212 8.34E-33 T 12-10-2018 IPR035926 NusB-like superfamily AFR_25925 9a560032dc4a3581ee35bd70e29276a6 497 Pfam PF13676 TIR domain 5 112 4.0E-28 T 12-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 AFR_25925 9a560032dc4a3581ee35bd70e29276a6 497 Gene3D G3DSA:3.40.50.300 158 311 5.5E-28 T 12-10-2018 AFR_25925 9a560032dc4a3581ee35bd70e29276a6 497 SUPERFAMILY SSF52540 163 405 1.38E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25925 9a560032dc4a3581ee35bd70e29276a6 497 Pfam PF00931 NB-ARC domain 190 367 2.3E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_25925 9a560032dc4a3581ee35bd70e29276a6 497 Gene3D G3DSA:3.40.50.10140 2 131 1.9E-20 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_25925 9a560032dc4a3581ee35bd70e29276a6 497 SMART SM00255 2 132 0.0044 T 12-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 AFR_25925 9a560032dc4a3581ee35bd70e29276a6 497 SUPERFAMILY SSF52200 4 122 1.96E-24 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_03370 44a78c8bb32ea4ea92ebed095f5596ae 333 Gene3D G3DSA:3.40.50.720 2 315 1.9E-83 T 12-10-2018 AFR_03370 44a78c8bb32ea4ea92ebed095f5596ae 333 SUPERFAMILY SSF55347 121 262 2.13E-26 T 12-10-2018 AFR_03370 44a78c8bb32ea4ea92ebed095f5596ae 333 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 115 4.4E-16 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_03370 44a78c8bb32ea4ea92ebed095f5596ae 333 Gene3D G3DSA:3.30.360.10 135 266 1.9E-83 T 12-10-2018 AFR_03370 44a78c8bb32ea4ea92ebed095f5596ae 333 SUPERFAMILY SSF51735 2 146 1.56E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03370 44a78c8bb32ea4ea92ebed095f5596ae 333 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 128 193 6.2E-8 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_28775 52b370204b94a12d88f0f1ab3a4bbe94 389 SUPERFAMILY SSF55874 272 375 1.29E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28775 52b370204b94a12d88f0f1ab3a4bbe94 389 Gene3D G3DSA:3.30.565.10 264 388 5.3E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28775 52b370204b94a12d88f0f1ab3a4bbe94 389 Pfam PF07730 Histidine kinase 202 263 8.4E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_07830 1c20741b5f3ec2a4cbd32d1a2d2f60a3 403 SUPERFAMILY SSF102114 26 402 2.22E-110 T 12-10-2018 AFR_07830 1c20741b5f3ec2a4cbd32d1a2d2f60a3 403 Gene3D G3DSA:3.80.30.20 14 329 4.2E-97 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFR_07830 1c20741b5f3ec2a4cbd32d1a2d2f60a3 403 Pfam PF04055 Radical SAM superfamily 34 206 4.1E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_07830 1c20741b5f3ec2a4cbd32d1a2d2f60a3 403 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 359 3.0E-77 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 AFR_07830 1c20741b5f3ec2a4cbd32d1a2d2f60a3 403 SMART SM00729 29 252 3.3E-55 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 SUPERFAMILY SSF53474 124 330 1.06E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 42 252 2.6E-39 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 SUPERFAMILY SSF49384 326 430 1.12E-29 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 Gene3D G3DSA:3.40.50.1820 16 311 7.6E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 SMART SM00637 331 429 2.4E-41 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 SUPERFAMILY SSF53474 14 100 5.59E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 Gene3D G3DSA:2.60.40.290 326 431 1.9E-32 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 Pfam PF00553 Cellulose binding domain 331 429 1.4E-26 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18035 b0155d11cf97e2ba9a43f0152113471d 432 Pfam PF10503 Esterase PHB depolymerase 42 231 2.1E-22 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AFR_11795 33b982c85cb08573d20aed255c5afddd 278 SUPERFAMILY SSF55729 62 256 3.09E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_11795 33b982c85cb08573d20aed255c5afddd 278 Pfam PF13480 Acetyltransferase (GNAT) domain 123 229 1.0E-5 T 12-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AFR_11795 33b982c85cb08573d20aed255c5afddd 278 Gene3D G3DSA:3.40.630.30 39 259 5.7E-29 T 12-10-2018 AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 Pfam PF12833 Helix-turn-helix domain 207 280 2.7E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 Pfam PF06719 AraC-type transcriptional regulator N-terminus 22 171 5.9E-46 T 12-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 237 279 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 SUPERFAMILY SSF51215 41 139 9.15E-5 T 12-10-2018 IPR037923 Transcription regulator HTH-like AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 SMART SM00342 199 283 2.9E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 SUPERFAMILY SSF46689 185 234 3.17E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 SUPERFAMILY SSF46689 236 281 1.43E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19140 5407dc28fcd0db9dc6afd1102b89fbb7 295 Gene3D G3DSA:1.10.10.60 184 287 3.1E-26 T 12-10-2018 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 SUPERFAMILY SSF47384 114 197 5.49E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 Gene3D G3DSA:1.10.287.130 81 197 3.0E-18 T 12-10-2018 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 Gene3D G3DSA:3.30.565.10 204 347 1.2E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 SMART SM00388 131 197 8.1E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 SMART SM00387 239 349 2.0E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 SUPERFAMILY SSF158472 77 125 1.44E-6 T 12-10-2018 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 239 347 1.0E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 SMART SM00304 77 130 1.0E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 346 1.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 327 1.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 288 1.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 302 1.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 SUPERFAMILY SSF55874 203 347 2.1E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28620 f9b96ccc034eb4ceb1238b83d635c240 350 Pfam PF00512 His Kinase A (phospho-acceptor) domain 133 197 3.7E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13380 e015759691b97429fdf2c2a915f80f08 252 PRINTS PR00412 Epoxide hydrolase signature 223 245 2.0E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13380 e015759691b97429fdf2c2a915f80f08 252 PRINTS PR00412 Epoxide hydrolase signature 68 81 2.0E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13380 e015759691b97429fdf2c2a915f80f08 252 PRINTS PR00412 Epoxide hydrolase signature 82 95 2.0E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13380 e015759691b97429fdf2c2a915f80f08 252 PRINTS PR00412 Epoxide hydrolase signature 7 25 2.0E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13380 e015759691b97429fdf2c2a915f80f08 252 Pfam PF12697 Alpha/beta hydrolase family 3 239 6.6E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13380 e015759691b97429fdf2c2a915f80f08 252 Gene3D G3DSA:3.40.50.1820 2 247 8.0E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13380 e015759691b97429fdf2c2a915f80f08 252 SUPERFAMILY SSF53474 3 248 7.12E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21285 248b44aa1cc82167629db50d4b79792a 286 Gene3D G3DSA:1.10.1740.10 2 85 8.8E-20 T 12-10-2018 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 Gene3D G3DSA:1.20.140.160 86 234 1.1E-33 T 12-10-2018 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 SUPERFAMILY SSF88946 12 87 2.55E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 PIRSF PIRSF000770 1 251 2.1E-54 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 Pfam PF04545 Sigma-70, region 4 181 228 3.5E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 SUPERFAMILY SSF88659 154 232 4.67E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_21285 248b44aa1cc82167629db50d4b79792a 286 Pfam PF04542 Sigma-70 region 2 15 87 1.2E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 Pfam PF04539 Sigma-70 region 3 101 166 1.9E-6 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 SUPERFAMILY SSF88659 89 156 2.18E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_21285 248b44aa1cc82167629db50d4b79792a 286 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 229 7.4E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 PRINTS PR00046 Major sigma-70 factor signature 201 216 3.7E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 PRINTS PR00046 Major sigma-70 factor signature 42 55 3.7E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 PRINTS PR00046 Major sigma-70 factor signature 184 196 3.7E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_21285 248b44aa1cc82167629db50d4b79792a 286 PRINTS PR00046 Major sigma-70 factor signature 216 227 3.7E-5 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_29060 b8a8ee48f26671c52e465d4ff82cd44d 441 Gene3D G3DSA:2.120.10.10 108 280 1.4E-5 T 12-10-2018 AFR_29060 b8a8ee48f26671c52e465d4ff82cd44d 441 Pfam PF15892 BNR repeat-containing family member 58 345 4.1E-82 T 12-10-2018 IPR039469 BNR repeat-containing family member AFR_12890 658f5bfeb8a7c09b894218951c15140b 453 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 48 81 - T 12-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 AFR_12890 658f5bfeb8a7c09b894218951c15140b 453 SUPERFAMILY SSF56176 9 211 5.14E-44 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_12890 658f5bfeb8a7c09b894218951c15140b 453 Pfam PF01565 FAD binding domain 48 182 9.6E-23 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_12890 658f5bfeb8a7c09b894218951c15140b 453 Gene3D G3DSA:3.30.465.10 114 441 7.7E-86 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_12890 658f5bfeb8a7c09b894218951c15140b 453 Gene3D G3DSA:3.30.43.10 24 101 4.0E-18 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_12890 658f5bfeb8a7c09b894218951c15140b 453 Gene3D G3DSA:3.40.462.20 210 414 7.7E-86 T 12-10-2018 AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 195 1.8E-4 T 12-10-2018 AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 SUPERFAMILY SSF51735 5 260 1.02E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 Gene3D G3DSA:3.40.50.720 2 263 1.9E-58 T 12-10-2018 AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 Pfam PF00106 short chain dehydrogenase 9 198 2.7E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13030 5de6c11716c5f822ee6b1823a6189de6 271 PIRSF PIRSF000126 3 267 1.8E-69 T 12-10-2018 AFR_07740 c11d833a76e51139cceca902e71081f1 283 Gene3D G3DSA:3.40.50.10170 1 151 5.2E-44 T 12-10-2018 AFR_07740 c11d833a76e51139cceca902e71081f1 283 SUPERFAMILY SSF82549 1 280 3.66E-74 T 12-10-2018 AFR_07740 c11d833a76e51139cceca902e71081f1 283 Gene3D G3DSA:3.30.1180.10 154 281 3.3E-37 T 12-10-2018 AFR_07740 c11d833a76e51139cceca902e71081f1 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 1.2E-82 T 12-10-2018 IPR003797 DegV AFR_07740 c11d833a76e51139cceca902e71081f1 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 278 2.9E-76 T 12-10-2018 IPR003797 DegV AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 Pfam PF00849 RNA pseudouridylate synthase 71 201 2.2E-20 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 SMART SM00363 10 73 8.8E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 Pfam PF01479 S4 domain 11 51 8.6E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 108 122 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 Gene3D G3DSA:3.10.290.10 4 65 1.1E-22 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 Gene3D G3DSA:3.30.70.580 71 237 7.9E-52 T 12-10-2018 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 SUPERFAMILY SSF55120 71 237 4.14E-42 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 Gene3D G3DSA:3.30.70.1560 137 220 7.9E-52 T 12-10-2018 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 75 233 7.6E-45 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFR_29630 c9a3e5e0afc89e67a65a73d774fb362b 246 SUPERFAMILY SSF55174 10 63 5.69E-11 T 12-10-2018 AFR_10295 9fd477c77fa9e2f2615a6bf9de7a2d5f 173 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 5 171 3.8E-34 T 12-10-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 Pfam PF00072 Response regulator receiver domain 9 116 1.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 9.4E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 SMART SM00421 146 203 4.7E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 Gene3D G3DSA:3.40.50.12740 6 209 4.8E-70 T 12-10-2018 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 SUPERFAMILY SSF52172 5 138 3.13E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 SUPERFAMILY SSF46894 138 209 2.69E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_34195 89f5ffa08fdcf1530d7a49fc66d5720c 217 SMART SM00448 6 119 1.0E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11500 cff732a5d5c53920ffae2060171da8b7 363 Gene3D G3DSA:3.40.50.300 3 168 2.4E-25 T 12-10-2018 AFR_11500 cff732a5d5c53920ffae2060171da8b7 363 Gene3D G3DSA:3.40.50.300 202 362 9.0E-15 T 12-10-2018 AFR_11500 cff732a5d5c53920ffae2060171da8b7 363 SUPERFAMILY SSF52540 204 357 4.48E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11500 cff732a5d5c53920ffae2060171da8b7 363 SUPERFAMILY SSF52540 4 155 1.3E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09050 1a1cf787cfa1416f11de90fe0941961e 141 Pfam PF03994 Domain of Unknown Function (DUF350) 15 69 4.2E-17 T 12-10-2018 IPR007140 Protein of unknown function DUF350 AFR_09050 1a1cf787cfa1416f11de90fe0941961e 141 Pfam PF03994 Domain of Unknown Function (DUF350) 86 140 5.0E-14 T 12-10-2018 IPR007140 Protein of unknown function DUF350 AFR_33880 a14f047ce103bb32b4a36f9d9abc8c85 464 Gene3D G3DSA:3.40.462.40 270 415 1.8E-25 T 12-10-2018 AFR_33880 a14f047ce103bb32b4a36f9d9abc8c85 464 Gene3D G3DSA:3.30.465.10 105 220 2.6E-39 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_33880 a14f047ce103bb32b4a36f9d9abc8c85 464 SUPERFAMILY SSF55103 227 461 1.24E-34 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFR_33880 a14f047ce103bb32b4a36f9d9abc8c85 464 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 459 5.2E-39 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFR_33880 a14f047ce103bb32b4a36f9d9abc8c85 464 Pfam PF01565 FAD binding domain 47 185 2.5E-35 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_33880 a14f047ce103bb32b4a36f9d9abc8c85 464 SUPERFAMILY SSF56176 3 221 5.61E-53 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_33880 a14f047ce103bb32b4a36f9d9abc8c85 464 Gene3D G3DSA:3.30.43.10 1 98 2.7E-18 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_18865 c9587a60b9cba624449104a37aed39ed 181 Gene3D G3DSA:3.10.350.10 131 180 2.5E-11 T 12-10-2018 IPR036779 LysM domain superfamily AFR_18865 c9587a60b9cba624449104a37aed39ed 181 Pfam PF01476 LysM domain 134 179 1.1E-7 T 12-10-2018 IPR018392 LysM domain AFR_18865 c9587a60b9cba624449104a37aed39ed 181 SUPERFAMILY SSF53955 36 113 5.63E-33 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_18865 c9587a60b9cba624449104a37aed39ed 181 Pfam PF06737 Transglycosylase-like domain 37 110 3.7E-36 T 12-10-2018 IPR010618 Transglycosylase-like AFR_18865 c9587a60b9cba624449104a37aed39ed 181 SUPERFAMILY SSF54106 133 181 3.14E-6 T 12-10-2018 AFR_18865 c9587a60b9cba624449104a37aed39ed 181 Gene3D G3DSA:1.10.530.10 15 117 2.8E-37 T 12-10-2018 AFR_19320 8db1272ccaf869bf7f62e94d3e040060 486 Pfam PF00171 Aldehyde dehydrogenase family 18 475 3.7E-148 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_19320 8db1272ccaf869bf7f62e94d3e040060 486 SUPERFAMILY SSF53720 4 480 1.57E-146 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_19320 8db1272ccaf869bf7f62e94d3e040060 486 Gene3D G3DSA:3.40.605.10 9 472 4.9E-155 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_19320 8db1272ccaf869bf7f62e94d3e040060 486 Gene3D G3DSA:3.40.309.10 257 445 4.9E-155 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_19340 2b2203deadfb4a5eba71174310ba6d08 288 SUPERFAMILY SSF161098 50 274 4.45E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19340 2b2203deadfb4a5eba71174310ba6d08 288 Gene3D G3DSA:1.10.3720.10 46 286 1.4E-67 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19340 2b2203deadfb4a5eba71174310ba6d08 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 279 1.8E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_13020 66bdee8465a4a843351cd92429f561d1 282 Gene3D G3DSA:3.90.25.10 120 255 3.1E-47 T 12-10-2018 AFR_13020 66bdee8465a4a843351cd92429f561d1 282 Gene3D G3DSA:3.40.50.720 5 253 3.1E-47 T 12-10-2018 AFR_13020 66bdee8465a4a843351cd92429f561d1 282 Pfam PF13460 NAD(P)H-binding 9 100 8.0E-7 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_13020 66bdee8465a4a843351cd92429f561d1 282 SUPERFAMILY SSF51735 3 263 5.6E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_21085 21ed0c41f9044e3b689ab11510738cbb 150 SMART SM00240 67 117 1.6E-15 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFR_21085 21ed0c41f9044e3b689ab11510738cbb 150 Pfam PF00498 FHA domain 69 131 4.7E-21 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFR_21085 21ed0c41f9044e3b689ab11510738cbb 150 SUPERFAMILY SSF49879 41 140 1.82E-33 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 AFR_21085 21ed0c41f9044e3b689ab11510738cbb 150 Gene3D G3DSA:2.60.200.20 29 144 1.2E-38 T 12-10-2018 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 SUPERFAMILY SSF46894 151 215 8.84E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 SMART SM00421 160 217 3.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 SMART SM00448 5 130 6.5E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 SUPERFAMILY SSF52172 4 147 1.99E-23 T 12-10-2018 IPR011006 CheY-like superfamily AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 Gene3D G3DSA:3.40.50.12740 5 226 1.1E-47 T 12-10-2018 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 213 2.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 Pfam PF00072 Response regulator receiver domain 8 118 8.4E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 1.7E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 1.7E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26875 6c7dbfa3e26fc555861d682a463ce0c9 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 1.7E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_19710 690cd5d35992e83796d48518968663fe 655 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 193 388 3.6E-43 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_19710 690cd5d35992e83796d48518968663fe 655 Gene3D G3DSA:3.30.450.20 3 140 9.8E-29 T 12-10-2018 AFR_19710 690cd5d35992e83796d48518968663fe 655 Gene3D G3DSA:3.30.565.10 390 526 3.4E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19710 690cd5d35992e83796d48518968663fe 655 SUPERFAMILY SSF52091 551 625 3.73E-9 T 12-10-2018 IPR036513 STAS domain superfamily AFR_19710 690cd5d35992e83796d48518968663fe 655 SUPERFAMILY SSF55874 424 516 8.32E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19710 690cd5d35992e83796d48518968663fe 655 Gene3D G3DSA:3.30.750.24 548 642 6.6E-12 T 12-10-2018 IPR036513 STAS domain superfamily AFR_19710 690cd5d35992e83796d48518968663fe 655 SMART SM00331 164 388 1.3E-32 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_19710 690cd5d35992e83796d48518968663fe 655 Pfam PF08448 PAS fold 13 123 1.5E-13 T 12-10-2018 IPR013656 PAS fold-4 AFR_19710 690cd5d35992e83796d48518968663fe 655 SUPERFAMILY SSF81606 174 386 3.14E-11 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_19710 690cd5d35992e83796d48518968663fe 655 Pfam PF01740 STAS domain 551 629 1.8E-6 T 12-10-2018 IPR002645 STAS domain AFR_19710 690cd5d35992e83796d48518968663fe 655 SUPERFAMILY SSF55785 9 122 2.79E-7 T 12-10-2018 IPR035965 PAS domain superfamily AFR_19710 690cd5d35992e83796d48518968663fe 655 Gene3D G3DSA:3.60.40.10 160 389 9.9E-56 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_19710 690cd5d35992e83796d48518968663fe 655 Pfam PF13581 Histidine kinase-like ATPase domain 399 512 2.2E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_10705 c189ef6ea038d6cb998ecccf3a7bc88c 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 5.6E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_10705 c189ef6ea038d6cb998ecccf3a7bc88c 335 Gene3D G3DSA:3.90.180.10 8 315 7.2E-69 T 12-10-2018 AFR_10705 c189ef6ea038d6cb998ecccf3a7bc88c 335 SUPERFAMILY SSF51735 145 302 2.32E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_10705 c189ef6ea038d6cb998ecccf3a7bc88c 335 SUPERFAMILY SSF50129 1 177 7.86E-43 T 12-10-2018 IPR011032 GroES-like superfamily AFR_10705 c189ef6ea038d6cb998ecccf3a7bc88c 335 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_10705 c189ef6ea038d6cb998ecccf3a7bc88c 335 Pfam PF00107 Zinc-binding dehydrogenase 178 284 1.4E-7 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_10705 c189ef6ea038d6cb998ecccf3a7bc88c 335 Gene3D G3DSA:3.40.50.720 155 280 7.2E-69 T 12-10-2018 AFR_13900 bb242b7bb5b3b4d702862d21e1576625 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13900 bb242b7bb5b3b4d702862d21e1576625 186 SUPERFAMILY SSF46689 3 69 4.57E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13900 bb242b7bb5b3b4d702862d21e1576625 186 SUPERFAMILY SSF48498 73 180 6.82E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13900 bb242b7bb5b3b4d702862d21e1576625 186 Gene3D G3DSA:1.10.357.10 6 185 3.5E-44 T 12-10-2018 AFR_29155 44f3f2ed1402b2224f8e7d2443e68e5b 312 SUPERFAMILY SSF46689 251 302 1.86E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29155 44f3f2ed1402b2224f8e7d2443e68e5b 312 SMART SM00342 215 298 1.1E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_29155 44f3f2ed1402b2224f8e7d2443e68e5b 312 Pfam PF12833 Helix-turn-helix domain 221 298 5.1E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_29155 44f3f2ed1402b2224f8e7d2443e68e5b 312 SUPERFAMILY SSF51215 42 179 7.98E-6 T 12-10-2018 IPR037923 Transcription regulator HTH-like AFR_29155 44f3f2ed1402b2224f8e7d2443e68e5b 312 Gene3D G3DSA:1.10.10.60 195 307 1.1E-25 T 12-10-2018 AFR_29155 44f3f2ed1402b2224f8e7d2443e68e5b 312 SUPERFAMILY SSF46689 198 249 6.72E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29155 44f3f2ed1402b2224f8e7d2443e68e5b 312 Pfam PF12852 Cupin 2 183 4.5E-35 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 Pfam PF00106 short chain dehydrogenase 13 204 4.1E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 SUPERFAMILY SSF51735 8 271 1.95E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 196 1.2E-4 T 12-10-2018 AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 Gene3D G3DSA:3.40.50.720 2 275 1.1E-65 T 12-10-2018 AFR_18725 145a0d144a1ea85dce46f126d7fc812b 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13005 a18c31552f4f3678bd1547861d384fd9 919 SUPERFAMILY SSF56601 526 912 2.25E-87 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_13005 a18c31552f4f3678bd1547861d384fd9 919 Gene3D G3DSA:3.40.710.10 510 918 2.0E-120 T 12-10-2018 AFR_13005 a18c31552f4f3678bd1547861d384fd9 919 Pfam PF00561 alpha/beta hydrolase fold 75 232 1.1E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13005 a18c31552f4f3678bd1547861d384fd9 919 SUPERFAMILY SSF53474 74 278 4.28E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13005 a18c31552f4f3678bd1547861d384fd9 919 Pfam PF00144 Beta-lactamase 531 899 1.7E-67 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_04885 c0f83fdd836e8fae9a75b3eebea0d9f8 391 Gene3D G3DSA:1.10.10.10 3 76 3.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04885 c0f83fdd836e8fae9a75b3eebea0d9f8 391 Gene3D G3DSA:3.30.420.40 91 378 6.2E-65 T 12-10-2018 AFR_04885 c0f83fdd836e8fae9a75b3eebea0d9f8 391 Gene3D G3DSA:3.30.420.40 208 368 6.2E-65 T 12-10-2018 AFR_04885 c0f83fdd836e8fae9a75b3eebea0d9f8 391 SUPERFAMILY SSF53067 209 388 1.11E-41 T 12-10-2018 AFR_04885 c0f83fdd836e8fae9a75b3eebea0d9f8 391 Pfam PF00480 ROK family 91 381 4.9E-46 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_04885 c0f83fdd836e8fae9a75b3eebea0d9f8 391 SUPERFAMILY SSF46785 10 74 8.19E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_04885 c0f83fdd836e8fae9a75b3eebea0d9f8 391 SUPERFAMILY SSF53067 82 207 2.3E-12 T 12-10-2018 AFR_27965 e8924418beb651b28d68fc9cf12fe60b 343 Gene3D G3DSA:3.30.70.20 20 284 3.6E-56 T 12-10-2018 AFR_27965 e8924418beb651b28d68fc9cf12fe60b 343 PIRSF PIRSF036298 17 91 3.6E-14 T 12-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 AFR_27965 e8924418beb651b28d68fc9cf12fe60b 343 PIRSF PIRSF036298 142 340 3.8E-49 T 12-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 AFR_27965 e8924418beb651b28d68fc9cf12fe60b 343 SUPERFAMILY SSF54862 25 271 4.08E-52 T 12-10-2018 AFR_27965 e8924418beb651b28d68fc9cf12fe60b 343 Pfam PF13247 4Fe-4S dicluster domain 158 253 1.2E-23 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_27965 e8924418beb651b28d68fc9cf12fe60b 343 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 198 209 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_35690 a41b7e4e31628e4beebd6f518d08e673 412 SUPERFAMILY SSF50475 4 188 3.37E-47 T 12-10-2018 AFR_35690 a41b7e4e31628e4beebd6f518d08e673 412 SUPERFAMILY SSF55729 224 394 1.11E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35690 a41b7e4e31628e4beebd6f518d08e673 412 Gene3D G3DSA:3.40.630.30 216 412 7.1E-48 T 12-10-2018 AFR_35690 a41b7e4e31628e4beebd6f518d08e673 412 Pfam PF13302 Acetyltransferase (GNAT) domain 230 368 3.3E-20 T 12-10-2018 IPR000182 GNAT domain AFR_35690 a41b7e4e31628e4beebd6f518d08e673 412 Gene3D G3DSA:2.30.110.10 5 215 1.6E-56 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_35690 a41b7e4e31628e4beebd6f518d08e673 412 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 23 167 6.5E-36 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related AFR_11905 a22ba12524ca4e74b2d6a9360f583ed7 125 SUPERFAMILY SSF55874 27 123 1.83E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11905 a22ba12524ca4e74b2d6a9360f583ed7 125 Gene3D G3DSA:3.30.565.10 7 125 2.0E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11905 a22ba12524ca4e74b2d6a9360f583ed7 125 Pfam PF13581 Histidine kinase-like ATPase domain 12 122 5.6E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_04880 3323eface4b4402cf9e8d59c686973f7 585 Pfam PF00005 ABC transporter 351 500 1.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04880 3323eface4b4402cf9e8d59c686973f7 585 Gene3D G3DSA:1.20.1560.10 2 322 3.5E-56 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_04880 3323eface4b4402cf9e8d59c686973f7 585 SMART SM00382 360 546 3.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_04880 3323eface4b4402cf9e8d59c686973f7 585 SUPERFAMILY SSF90123 12 313 2.22E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_04880 3323eface4b4402cf9e8d59c686973f7 585 Gene3D G3DSA:3.40.50.300 333 573 2.1E-74 T 12-10-2018 AFR_04880 3323eface4b4402cf9e8d59c686973f7 585 Pfam PF00664 ABC transporter transmembrane region 24 292 7.2E-29 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_04880 3323eface4b4402cf9e8d59c686973f7 585 SUPERFAMILY SSF52540 332 569 1.44E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29700 49a15a21879eaa275341b7e95d56487c 151 SMART SM00116 22 69 0.0077 T 12-10-2018 IPR000644 CBS domain AFR_29700 49a15a21879eaa275341b7e95d56487c 151 Pfam PF00571 CBS domain 22 65 4.2E-5 T 12-10-2018 IPR000644 CBS domain AFR_29700 49a15a21879eaa275341b7e95d56487c 151 Gene3D G3DSA:3.10.580.10 9 113 7.3E-11 T 12-10-2018 AFR_29700 49a15a21879eaa275341b7e95d56487c 151 SUPERFAMILY SSF54631 12 118 1.2E-11 T 12-10-2018 AFR_03265 502756fd41d08a04d449b56b158abc82 507 SUPERFAMILY SSF52540 14 235 1.3E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03265 502756fd41d08a04d449b56b158abc82 507 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_03265 502756fd41d08a04d449b56b158abc82 507 Gene3D G3DSA:3.40.50.300 13 251 3.8E-55 T 12-10-2018 AFR_03265 502756fd41d08a04d449b56b158abc82 507 Pfam PF00005 ABC transporter 31 180 1.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03265 502756fd41d08a04d449b56b158abc82 507 Pfam PF00005 ABC transporter 280 433 1.7E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03265 502756fd41d08a04d449b56b158abc82 507 Gene3D G3DSA:3.40.50.300 265 505 1.7E-46 T 12-10-2018 AFR_03265 502756fd41d08a04d449b56b158abc82 507 SMART SM00382 288 482 7.5E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03265 502756fd41d08a04d449b56b158abc82 507 SMART SM00382 39 222 3.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03265 502756fd41d08a04d449b56b158abc82 507 SUPERFAMILY SSF52540 276 495 1.54E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 SUPERFAMILY SSF47413 6 64 1.18E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 Gene3D G3DSA:3.40.50.2300 61 313 2.0E-71 T 12-10-2018 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 Pfam PF13377 Periplasmic binding protein-like domain 180 337 1.7E-39 T 12-10-2018 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 9.2E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 9.2E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 Gene3D G3DSA:1.10.260.40 1 60 7.3E-21 T 12-10-2018 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 SUPERFAMILY SSF53822 67 337 6.16E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 SMART SM00354 6 76 1.3E-29 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 2.9E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_40630 acd33d9bdd50502c7bd2222189b90f17 338 Gene3D G3DSA:3.40.50.2300 172 298 2.0E-71 T 12-10-2018 AFR_00225 7af3fa7e46fd2cceab052493288e60f8 279 SMART SM00740 190 255 4.7E-12 T 12-10-2018 IPR005543 PASTA domain AFR_00225 7af3fa7e46fd2cceab052493288e60f8 279 Gene3D G3DSA:3.30.10.20 190 255 1.3E-13 T 12-10-2018 AFR_00225 7af3fa7e46fd2cceab052493288e60f8 279 Pfam PF03793 PASTA domain 194 253 3.5E-12 T 12-10-2018 IPR005543 PASTA domain AFR_00750 70b72ab4c402e50a4747df2708c3fac9 367 SUPERFAMILY SSF102114 7 323 9.94E-30 T 12-10-2018 AFR_00750 70b72ab4c402e50a4747df2708c3fac9 367 Pfam PF04055 Radical SAM superfamily 14 159 2.0E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_00750 70b72ab4c402e50a4747df2708c3fac9 367 Gene3D G3DSA:3.20.20.70 7 359 3.0E-56 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 Gene3D G3DSA:3.40.225.10 5 215 1.6E-49 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 Gene3D G3DSA:3.40.50.720 398 673 9.0E-62 T 12-10-2018 AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 SUPERFAMILY SSF51735 406 673 5.25E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 209 2.7E-22 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 7 676 0.0 T 12-10-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 SMART SM01007 8 210 4.6E-32 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 SUPERFAMILY SSF53639 7 214 4.12E-30 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 427 670 2.1E-45 T 12-10-2018 AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 587 604 2.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 634 654 2.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 540 556 2.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 492 503 2.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 419 436 2.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03275 a1253f2406ed0a4d9fbb254f5221f329 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 566 585 2.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 Gene3D G3DSA:2.80.10.50 440 469 1.5E-8 T 12-10-2018 AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 Pfam PF04616 Glycosyl hydrolases family 43 30 317 8.2E-49 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 Pfam PF00652 Ricin-type beta-trefoil lectin domain 347 466 4.1E-22 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 SUPERFAMILY SSF75005 27 318 1.33E-44 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 SMART SM00458 341 469 8.4E-21 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 SUPERFAMILY SSF50370 338 467 1.13E-32 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 Gene3D G3DSA:2.80.10.50 340 439 5.6E-25 T 12-10-2018 AFR_12835 2c13a6e8239e1d203ea4e44a8537004e 469 Gene3D G3DSA:2.115.10.20 20 326 2.8E-62 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_26610 bf7be8c6fd8c65e3596ed282d508f4cc 270 Gene3D G3DSA:3.40.50.150 18 269 9.9E-37 T 12-10-2018 AFR_26610 bf7be8c6fd8c65e3596ed282d508f4cc 270 Pfam PF08241 Methyltransferase domain 50 142 4.4E-14 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_26610 bf7be8c6fd8c65e3596ed282d508f4cc 270 SUPERFAMILY SSF53335 28 268 2.19E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_11190 ec69cc9fdceed5a191c20470c4d8008e 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 320 1.1E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_11190 ec69cc9fdceed5a191c20470c4d8008e 327 SUPERFAMILY SSF161098 84 314 3.4E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11190 ec69cc9fdceed5a191c20470c4d8008e 327 Gene3D G3DSA:1.10.3720.10 81 324 3.8E-57 T 12-10-2018 IPR035906 MetI-like superfamily AFR_10585 857c608d90abb1fcd78323081d41ca9f 115 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 113 23.445 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 AFR_10585 857c608d90abb1fcd78323081d41ca9f 115 Gene3D G3DSA:2.20.28.270 3 79 1.2E-14 T 12-10-2018 IPR038638 RbpA superfamily AFR_10585 857c608d90abb1fcd78323081d41ca9f 115 Pfam PF13397 RNA polymerase-binding protein 6 108 9.0E-39 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 AFR_20835 416bfc89128842de6ff01dc12f2aea99 216 SUPERFAMILY SSF53474 20 205 2.32E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20835 416bfc89128842de6ff01dc12f2aea99 216 SMART SM01110 18 215 9.6E-51 T 12-10-2018 IPR000675 Cutinase/acetylxylan esterase GO:0016787 AFR_20835 416bfc89128842de6ff01dc12f2aea99 216 Gene3D G3DSA:3.40.50.1820 19 216 4.7E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20835 416bfc89128842de6ff01dc12f2aea99 216 Pfam PF01083 Cutinase 19 213 3.8E-39 T 12-10-2018 IPR000675 Cutinase/acetylxylan esterase GO:0016787 AFR_01705 5f83199870fce9d498e2529a3b7f5f2e 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 7.7E-23 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like AFR_01705 5f83199870fce9d498e2529a3b7f5f2e 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 20.17 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AFR_14815 5e49a4414dac09671f90c3f2202e5497 338 Pfam PF00801 PKD domain 159 214 1.4E-8 T 12-10-2018 IPR000601 PKD domain AFR_14815 5e49a4414dac09671f90c3f2202e5497 338 SUPERFAMILY SSF49299 154 224 1.7E-18 T 12-10-2018 IPR035986 PKD domain superfamily AFR_14815 5e49a4414dac09671f90c3f2202e5497 338 SMART SM00089 147 226 2.6E-11 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_14815 5e49a4414dac09671f90c3f2202e5497 338 Gene3D G3DSA:2.60.40.10 136 224 5.2E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 SUPERFAMILY SSF88713 352 536 1.66E-54 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 Gene3D G3DSA:3.20.20.370 354 545 7.9E-58 T 12-10-2018 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 267 277 - T 12-10-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 SUPERFAMILY SSF49384 567 656 1.33E-17 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 SUPERFAMILY SSF51445 44 342 8.1E-108 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 Gene3D G3DSA:2.60.40.290 567 656 8.9E-22 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 Pfam PF00331 Glycosyl hydrolase family 10 45 339 2.7E-108 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 SMART SM00637 570 653 3.6E-14 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 Pfam PF01522 Polysaccharide deacetylase 361 477 2.0E-30 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 Gene3D G3DSA:3.20.20.80 39 351 1.3E-119 T 12-10-2018 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 PRINTS PR00134 Glycosyl hydrolase family 10 signature 233 245 1.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 PRINTS PR00134 Glycosyl hydrolase family 10 signature 203 214 1.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 PRINTS PR00134 Glycosyl hydrolase family 10 signature 116 128 1.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 PRINTS PR00134 Glycosyl hydrolase family 10 signature 158 169 1.0E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_17715 b6c57ae1f745032f76f86b6f46d6f216 656 SMART SM00633 85 341 2.3E-130 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 Gene3D G3DSA:3.40.190.10 5 214 3.0E-70 T 12-10-2018 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 299 33.419 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 298 2.1E-87 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 Gene3D G3DSA:3.30.160.40 219 307 2.4E-25 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 SUPERFAMILY SSF54782 218 306 1.7E-22 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 Gene3D G3DSA:3.40.190.10 96 197 3.0E-70 T 12-10-2018 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 PRINTS PR00151 Porphobilinogen deaminase signature 72 91 4.4E-20 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 PRINTS PR00151 Porphobilinogen deaminase signature 120 137 4.4E-20 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 PRINTS PR00151 Porphobilinogen deaminase signature 139 156 4.4E-20 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 4.4E-20 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 210 1.0E-62 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 297 7.4E-20 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 PIRSF PIRSF001438 1 309 6.4E-107 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40175 cd9b7d05f7ce9ccc2fc9b9c93bb7c5cb 309 SUPERFAMILY SSF53850 4 217 1.09E-60 T 12-10-2018 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 PIRSF PIRSF000106 70 467 5.4E-79 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 Gene3D G3DSA:3.40.50.10380 52 236 1.6E-69 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 SUPERFAMILY SSF51735 239 460 4.89E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35540 3cdd81012ed671f23e81f27e03346779 485 SMART SM01274 94 227 4.0E-81 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 SUPERFAMILY SSF53223 88 237 3.88E-54 T 12-10-2018 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 SMART SM00919 239 461 4.0E-109 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 Pfam PF00390 Malic enzyme, N-terminal domain 96 227 1.3E-28 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 Pfam PF03949 Malic enzyme, NAD binding domain 241 455 3.6E-23 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFR_35540 3cdd81012ed671f23e81f27e03346779 485 Gene3D G3DSA:3.40.50.720 237 463 5.0E-71 T 12-10-2018 AFR_24995 56ff702db1a738374ba1dc4be7c4a08a 311 Pfam PF00685 Sulfotransferase domain 4 211 2.0E-21 T 12-10-2018 IPR000863 Sulfotransferase domain GO:0008146 AFR_24995 56ff702db1a738374ba1dc4be7c4a08a 311 SUPERFAMILY SSF52540 2 301 5.69E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24995 56ff702db1a738374ba1dc4be7c4a08a 311 Gene3D G3DSA:3.40.50.300 1 237 6.8E-66 T 12-10-2018 AFR_41625 7977d8b8efab78d18e0e5382d4d02d35 487 SMART SM00220 1 253 2.1E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_41625 7977d8b8efab78d18e0e5382d4d02d35 487 Gene3D G3DSA:1.10.510.10 83 259 1.4E-34 T 12-10-2018 AFR_41625 7977d8b8efab78d18e0e5382d4d02d35 487 Pfam PF00069 Protein kinase domain 8 250 9.2E-41 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_41625 7977d8b8efab78d18e0e5382d4d02d35 487 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 119 131 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_41625 7977d8b8efab78d18e0e5382d4d02d35 487 Gene3D G3DSA:3.30.200.20 3 81 3.2E-17 T 12-10-2018 AFR_41625 7977d8b8efab78d18e0e5382d4d02d35 487 SUPERFAMILY SSF56112 6 289 5.97E-58 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_00090 a55849af5b073afc9498e09f09565f52 173 Gene3D G3DSA:3.40.630.30 2 166 1.6E-20 T 12-10-2018 AFR_00090 a55849af5b073afc9498e09f09565f52 173 SUPERFAMILY SSF55729 4 136 5.23E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_00090 a55849af5b073afc9498e09f09565f52 173 Pfam PF00583 Acetyltransferase (GNAT) family 48 133 5.2E-12 T 12-10-2018 IPR000182 GNAT domain AFR_25545 a6ac7fc7d646eff770d3e8bc93e1840e 224 Gene3D G3DSA:3.40.225.10 4 222 1.6E-66 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFR_25545 a6ac7fc7d646eff770d3e8bc93e1840e 224 SUPERFAMILY SSF53639 5 215 1.96E-63 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFR_25545 a6ac7fc7d646eff770d3e8bc93e1840e 224 SMART SM01007 12 191 1.3E-62 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFR_25545 a6ac7fc7d646eff770d3e8bc93e1840e 224 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 189 2.4E-48 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFR_30765 4ec8c4a3fc26d97b90a000aeb4dc6107 227 Pfam PF07077 Protein of unknown function (DUF1345) 53 220 4.5E-10 T 12-10-2018 IPR009781 Protein of unknown function DUF1345 AFR_15470 de8087e7c10fc27004fe03283c602f04 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 6.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15470 de8087e7c10fc27004fe03283c602f04 201 Gene3D G3DSA:1.10.10.60 2 57 8.4E-13 T 12-10-2018 AFR_15470 de8087e7c10fc27004fe03283c602f04 201 Gene3D G3DSA:1.10.357.10 58 192 5.5E-19 T 12-10-2018 AFR_15470 de8087e7c10fc27004fe03283c602f04 201 SUPERFAMILY SSF46689 6 86 6.67E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15470 de8087e7c10fc27004fe03283c602f04 201 SUPERFAMILY SSF48498 81 193 1.46E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 SMART SM00642 247 620 1.8E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 SUPERFAMILY SSF51445 177 610 1.51E-111 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 Pfam PF00128 Alpha amylase, catalytic domain 267 340 1.1E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 101 719 43.097 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 125 204 1.6E-16 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 109 717 2.5E-272 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 SUPERFAMILY SSF81296 23 114 1.66E-16 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 621 718 2.6E-20 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 Gene3D G3DSA:2.60.40.10 11 218 5.4E-63 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 PIRSF PIRSF000463 15 720 1.5E-284 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 SUPERFAMILY SSF81296 131 198 3.64E-7 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 SUPERFAMILY SSF51011 617 718 4.46E-33 T 12-10-2018 AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 Gene3D G3DSA:2.60.40.1180 616 720 3.9E-38 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_27110 4114480c857a5c3ffa161c9a3adaa69e 720 Gene3D G3DSA:3.20.20.80 220 615 3.2E-178 T 12-10-2018 AFR_20045 f3d5c539575dab647c236d0557c5e1b2 557 Pfam PF00664 ABC transporter transmembrane region 36 288 1.2E-20 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_20045 f3d5c539575dab647c236d0557c5e1b2 557 Gene3D G3DSA:3.40.50.300 332 553 1.3E-37 T 12-10-2018 AFR_20045 f3d5c539575dab647c236d0557c5e1b2 557 SUPERFAMILY SSF90123 7 321 1.7E-49 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20045 f3d5c539575dab647c236d0557c5e1b2 557 Pfam PF00005 ABC transporter 426 476 1.5E-7 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20045 f3d5c539575dab647c236d0557c5e1b2 557 SUPERFAMILY SSF52540 383 544 4.05E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20045 f3d5c539575dab647c236d0557c5e1b2 557 Gene3D G3DSA:1.20.1560.10 2 319 4.9E-45 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20045 f3d5c539575dab647c236d0557c5e1b2 557 ProSitePatterns PS00211 ABC transporters family signature. 448 462 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07285 536a880ad12dab72da8775e9c827fdc5 288 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 285 87.823 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFR_07285 536a880ad12dab72da8775e9c827fdc5 288 Pfam PF03186 CobD/Cbib protein 1 263 1.9E-84 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFR_07285 536a880ad12dab72da8775e9c827fdc5 288 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 29 236 3.3E-50 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 SUPERFAMILY SSF69618 248 498 5.23E-69 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 Gene3D G3DSA:3.40.50.10090 251 489 9.1E-53 T 12-10-2018 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 12 210 6.1E-30 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 SUPERFAMILY SSF53790 9 251 4.06E-36 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 Gene3D G3DSA:3.40.50.10090 280 420 9.1E-53 T 12-10-2018 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 Pfam PF02602 Uroporphyrinogen-III synthase HemD 262 493 4.4E-65 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 Gene3D G3DSA:3.40.1010.10 1 122 2.9E-23 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_40170 46da21eb9ce8313fd6da5806b26ced95 528 Gene3D G3DSA:3.30.950.10 124 244 1.8E-9 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFR_09985 f128c55af98f796c6cca448d5834ebcd 799 SUPERFAMILY SSF56519 266 444 4.84E-33 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFR_09985 f128c55af98f796c6cca448d5834ebcd 799 Gene3D G3DSA:3.90.1310.30 261 444 2.4E-37 T 12-10-2018 AFR_09985 f128c55af98f796c6cca448d5834ebcd 799 Pfam PF03717 Penicillin-binding Protein dimerisation domain 268 412 3.6E-14 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFR_09985 f128c55af98f796c6cca448d5834ebcd 799 Gene3D G3DSA:3.30.450.330 446 781 1.9E-90 T 12-10-2018 AFR_09985 f128c55af98f796c6cca448d5834ebcd 799 Gene3D G3DSA:3.40.710.10 506 701 1.9E-90 T 12-10-2018 AFR_09985 f128c55af98f796c6cca448d5834ebcd 799 SUPERFAMILY SSF56601 389 788 2.36E-85 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_09985 f128c55af98f796c6cca448d5834ebcd 799 Pfam PF00905 Penicillin binding protein transpeptidase domain 470 776 4.0E-70 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_00060 ef48c9431e6b21a89da175f040a541cc 162 SUPERFAMILY SSF55729 3 144 8.27E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_00060 ef48c9431e6b21a89da175f040a541cc 162 Gene3D G3DSA:3.40.630.30 2 152 1.3E-22 T 12-10-2018 AFR_00060 ef48c9431e6b21a89da175f040a541cc 162 Pfam PF13302 Acetyltransferase (GNAT) domain 4 139 4.4E-12 T 12-10-2018 IPR000182 GNAT domain AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Gene3D G3DSA:3.30.450.20 165 290 6.8E-13 T 12-10-2018 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Pfam PF00989 PAS fold 176 291 1.6E-6 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Gene3D G3DSA:1.10.287.130 463 544 3.8E-17 T 12-10-2018 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Gene3D G3DSA:3.30.450.40 291 462 3.8E-22 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SMART SM00065 27 164 0.034 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SMART SM00065 317 470 7.4E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Gene3D G3DSA:3.30.565.10 548 702 7.1E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SUPERFAMILY SSF55874 532 699 3.41E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SUPERFAMILY SSF55781 30 151 1.65E-11 T 12-10-2018 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Pfam PF13185 GAF domain 325 457 1.3E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Pfam PF00512 His Kinase A (phospho-acceptor) domain 475 542 9.5E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SUPERFAMILY SSF55785 166 293 2.27E-10 T 12-10-2018 IPR035965 PAS domain superfamily AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 642 652 2.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 677 2.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 696 2.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 638 2.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SUPERFAMILY SSF55781 318 470 1.66E-17 T 12-10-2018 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 588 698 1.7E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SMART SM00387 587 699 3.3E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 Gene3D G3DSA:3.30.450.40 7 153 5.7E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SMART SM00388 475 542 3.4E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_06035 a79991712f904fd72e2b343f8c24b73c 705 SUPERFAMILY SSF47384 459 543 9.81E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_18915 6071e203b538de218aa625f85b02c270 454 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 42 287 2.3E-37 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AFR_18915 6071e203b538de218aa625f85b02c270 454 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 151 160 - T 12-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 AFR_18915 6071e203b538de218aa625f85b02c270 454 Gene3D G3DSA:3.20.20.80 19 329 5.1E-89 T 12-10-2018 AFR_18915 6071e203b538de218aa625f85b02c270 454 Pfam PF00553 Cellulose binding domain 358 449 1.7E-23 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_18915 6071e203b538de218aa625f85b02c270 454 SUPERFAMILY SSF51445 33 328 2.6E-78 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_18915 6071e203b538de218aa625f85b02c270 454 Gene3D G3DSA:2.60.40.290 353 453 4.0E-26 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_18915 6071e203b538de218aa625f85b02c270 454 SUPERFAMILY SSF49384 352 450 1.74E-26 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_18915 6071e203b538de218aa625f85b02c270 454 SMART SM00637 358 451 1.6E-35 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_41400 c026fc47cdf00a45fc748480bbbcff27 339 SUPERFAMILY SSF53335 8 329 5.15E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_41400 c026fc47cdf00a45fc748480bbbcff27 339 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 118 267 8.8E-13 T 12-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 AFR_41400 c026fc47cdf00a45fc748480bbbcff27 339 Gene3D G3DSA:3.40.50.12710 3 334 1.2E-33 T 12-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 AFR_32330 9d10a661470f60afc396c53b6bd8df84 399 Gene3D G3DSA:3.40.440.10 5 236 1.8E-63 T 12-10-2018 AFR_32330 9d10a661470f60afc396c53b6bd8df84 399 SUPERFAMILY SSF52540 3 392 1.38E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32330 9d10a661470f60afc396c53b6bd8df84 399 SMART SM00788 3 394 7.1E-22 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_32330 9d10a661470f60afc396c53b6bd8df84 399 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 399 46.903 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_32330 9d10a661470f60afc396c53b6bd8df84 399 Gene3D G3DSA:3.90.170.10 249 347 2.9E-16 T 12-10-2018 AFR_32330 9d10a661470f60afc396c53b6bd8df84 399 Gene3D G3DSA:1.10.300.10 99 189 1.8E-63 T 12-10-2018 AFR_32330 9d10a661470f60afc396c53b6bd8df84 399 Pfam PF00709 Adenylosuccinate synthetase 4 341 1.7E-74 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFR_41810 40834704db0924b2a742a002d4c51e71 1182 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 239 363 7.7E-15 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 AFR_41810 40834704db0924b2a742a002d4c51e71 1182 Gene3D G3DSA:1.10.8.60 7 229 6.5E-94 T 12-10-2018 AFR_41810 40834704db0924b2a742a002d4c51e71 1182 SUPERFAMILY SSF48019 246 363 6.38E-22 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFR_41810 40834704db0924b2a742a002d4c51e71 1182 SMART SM00382 36 198 7.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41810 40834704db0924b2a742a002d4c51e71 1182 Pfam PF13177 DNA polymerase III, delta subunit 19 177 5.0E-39 T 12-10-2018 AFR_41810 40834704db0924b2a742a002d4c51e71 1182 SUPERFAMILY SSF52540 32 221 4.03E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41810 40834704db0924b2a742a002d4c51e71 1182 Gene3D G3DSA:3.40.50.300 12 178 6.5E-94 T 12-10-2018 AFR_41810 40834704db0924b2a742a002d4c51e71 1182 Gene3D G3DSA:1.20.272.10 244 365 2.0E-6 T 12-10-2018 AFR_41810 40834704db0924b2a742a002d4c51e71 1182 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 4 362 7.7E-115 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 AFR_35615 0a616758924bb649dcf46fd01650d8b3 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 206 9.5E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_35615 0a616758924bb649dcf46fd01650d8b3 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 114 3.3E-20 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFR_35615 0a616758924bb649dcf46fd01650d8b3 224 SUPERFAMILY SSF161098 13 205 1.57E-34 T 12-10-2018 IPR035906 MetI-like superfamily AFR_35615 0a616758924bb649dcf46fd01650d8b3 224 Gene3D G3DSA:1.10.3720.10 8 222 1.7E-38 T 12-10-2018 IPR035906 MetI-like superfamily AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 SUPERFAMILY SSF88659 133 190 1.16E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 Gene3D G3DSA:1.10.10.10 126 194 1.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 189 4.7E-28 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 Pfam PF08281 Sigma-70, region 4 135 185 1.8E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 48 79 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 14 201 1.2E-106 T 12-10-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 Gene3D G3DSA:1.10.1740.10 10 96 8.2E-36 T 12-10-2018 AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 Pfam PF04542 Sigma-70 region 2 31 93 3.0E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_38120 f2df27193204a5905f2c854f3f754d8b 210 SUPERFAMILY SSF88946 19 109 1.02E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 Gene3D G3DSA:3.40.50.300 730 932 8.3E-82 T 12-10-2018 AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 SMART SM00487 511 699 3.0E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 Gene3D G3DSA:3.40.50.10810 516 722 2.1E-66 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 SMART SM00490 834 918 1.7E-19 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 Pfam PF12419 SNF2 Helicase protein 336 468 9.5E-36 T 12-10-2018 IPR022138 Helicase SWF/SNF-related AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 Pfam PF00271 Helicase conserved C-terminal domain 806 918 6.6E-13 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 Gene3D G3DSA:1.20.120.850 745 968 8.3E-82 T 12-10-2018 AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 SUPERFAMILY SSF52540 503 721 3.55E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 SUPERFAMILY SSF52540 727 976 1.31E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24910 b86c791ad5352e6dae307da64c4e151c 981 Pfam PF00176 SNF2 family N-terminal domain 534 790 4.6E-60 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 Gene3D G3DSA:3.40.50.720 4 262 1.8E-63 T 12-10-2018 AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 257 3.8E-43 T 12-10-2018 AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 SUPERFAMILY SSF51735 10 258 8.44E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11340 b46d35a21743390d18bb0bbe467b6c81 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12475 571065a7fd668b7f03752f7a558aa747 351 SUPERFAMILY SSF53067 3 290 1.45E-7 T 12-10-2018 AFR_12475 571065a7fd668b7f03752f7a558aa747 351 Gene3D G3DSA:3.30.420.40 166 205 1.5E-19 T 12-10-2018 AFR_12475 571065a7fd668b7f03752f7a558aa747 351 Gene3D G3DSA:3.30.420.40 5 162 1.5E-19 T 12-10-2018 AFR_12475 571065a7fd668b7f03752f7a558aa747 351 SUPERFAMILY SSF53067 4 153 2.46E-8 T 12-10-2018 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 SUPERFAMILY SSF55979 241 344 4.13E-5 T 12-10-2018 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 Pfam PF02767 DNA polymerase III beta subunit, central domain 119 231 2.9E-18 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 SMART SM00480 48 341 2.0E-6 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 Gene3D G3DSA:1.10.1660.10 1 115 8.1E-20 T 12-10-2018 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 SUPERFAMILY SSF46955 2 105 4.76E-21 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 Pfam PF13411 MerR HTH family regulatory protein 2 69 5.0E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 Gene3D G3DSA:3.10.150.10 116 235 6.2E-24 T 12-10-2018 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 SMART SM00422 2 72 2.6E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 Gene3D G3DSA:3.10.150.10 240 345 1.1E-5 T 12-10-2018 AFR_38565 46ad6edf54645e72ac8276f9d7b24f66 345 SUPERFAMILY SSF55979 116 234 1.05E-14 T 12-10-2018 AFR_03170 3a013b6943aedd8f1fb1672cbb6e8e72 250 SUPERFAMILY SSF53335 17 237 2.39E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_03170 3a013b6943aedd8f1fb1672cbb6e8e72 250 Gene3D G3DSA:2.20.25.570 152 208 2.0E-75 T 12-10-2018 AFR_03170 3a013b6943aedd8f1fb1672cbb6e8e72 250 Gene3D G3DSA:3.40.50.150 17 247 2.0E-75 T 12-10-2018 AFR_03170 3a013b6943aedd8f1fb1672cbb6e8e72 250 Pfam PF13649 Methyltransferase domain 51 144 3.1E-10 T 12-10-2018 AFR_16920 c879104345fd984ff083e2765ff0b139 356 SUPERFAMILY SSF52518 26 346 1.3E-91 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_16920 c879104345fd984ff083e2765ff0b139 356 Pfam PF00676 Dehydrogenase E1 component 40 300 1.8E-71 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFR_16920 c879104345fd984ff083e2765ff0b139 356 Gene3D G3DSA:3.40.50.970 2 344 1.1E-106 T 12-10-2018 AFR_16920 c879104345fd984ff083e2765ff0b139 356 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 8 343 5.5E-125 T 12-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AFR_21785 dee29b1f190b09baa0b6bef2618a0ae6 269 Gene3D G3DSA:3.90.550.10 16 257 1.8E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_21785 dee29b1f190b09baa0b6bef2618a0ae6 269 SUPERFAMILY SSF53448 19 232 8.44E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_21785 dee29b1f190b09baa0b6bef2618a0ae6 269 Pfam PF00535 Glycosyl transferase family 2 22 184 9.2E-30 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 Pfam PF13424 Tetratricopeptide repeat 154 228 1.3E-19 T 12-10-2018 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 Pfam PF13424 Tetratricopeptide repeat 75 144 3.5E-14 T 12-10-2018 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 SUPERFAMILY SSF48452 25 189 2.05E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 Gene3D G3DSA:1.25.40.10 2 153 8.4E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 SMART SM00028 113 146 1.5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 SMART SM00028 197 230 400.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 SMART SM00028 155 188 6.3E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 SUPERFAMILY SSF48452 151 268 7.32E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 Pfam PF13176 Tetratricopeptide repeat 241 269 0.022 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 PRINTS PR00381 Kinesin light chain signature 86 104 4.8E-5 T 12-10-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 PRINTS PR00381 Kinesin light chain signature 230 251 4.8E-5 T 12-10-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 PRINTS PR00381 Kinesin light chain signature 195 215 4.8E-5 T 12-10-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 PRINTS PR00381 Kinesin light chain signature 151 168 4.8E-5 T 12-10-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 Pfam PF13374 Tetratricopeptide repeat 36 68 0.0013 T 12-10-2018 AFR_25935 fbc109de067406cc89760a85e5ea1fc6 271 Gene3D G3DSA:1.25.40.10 154 271 3.4E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_29505 f4f41f5a618e9f3cea58d138439c00f1 261 SUPERFAMILY SSF53474 7 260 1.27E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29505 f4f41f5a618e9f3cea58d138439c00f1 261 Pfam PF07859 alpha/beta hydrolase fold 31 241 7.0E-25 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 SUPERFAMILY SSF46785 6 84 4.46E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 Pfam PF03466 LysR substrate binding domain 93 288 7.9E-27 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 SUPERFAMILY SSF53850 93 289 4.1E-26 T 12-10-2018 AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 Gene3D G3DSA:3.40.190.10 97 279 7.6E-25 T 12-10-2018 AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 Gene3D G3DSA:1.10.10.10 6 92 6.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 7.0E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 Gene3D G3DSA:3.40.190.10 166 262 7.6E-25 T 12-10-2018 AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_15775 bd6b4d5c142c37ba126d8a60999ab0e2 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_29720 60c7b1da47e83d9301a293f86210042e 301 Gene3D G3DSA:2.60.260.20 199 300 3.1E-29 T 12-10-2018 AFR_29720 60c7b1da47e83d9301a293f86210042e 301 SUPERFAMILY SSF49493 204 290 1.7E-21 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFR_29720 60c7b1da47e83d9301a293f86210042e 301 Gene3D G3DSA:2.60.260.20 70 194 6.7E-22 T 12-10-2018 AFR_29720 60c7b1da47e83d9301a293f86210042e 301 SUPERFAMILY SSF57938 87 154 7.06E-11 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily AFR_29720 60c7b1da47e83d9301a293f86210042e 301 Gene3D G3DSA:2.10.230.10 100 152 6.7E-22 T 12-10-2018 AFR_29720 60c7b1da47e83d9301a293f86210042e 301 Pfam PF01556 DnaJ C terminal domain 76 279 5.6E-33 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal AFR_29720 60c7b1da47e83d9301a293f86210042e 301 SUPERFAMILY SSF49493 68 211 1.83E-16 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 116 456 1.7E-103 T 12-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 Gene3D G3DSA:3.30.379.10 1 112 2.6E-23 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 1 112 8.5E-18 T 12-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 Gene3D G3DSA:3.20.20.80 115 456 1.9E-125 T 12-10-2018 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 SUPERFAMILY SSF51445 116 469 6.58E-109 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 SUPERFAMILY SSF55545 1 115 7.07E-22 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 PRINTS PR00738 Glycosyl hydrolase family 20 signature 278 291 9.2E-43 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 PRINTS PR00738 Glycosyl hydrolase family 20 signature 439 456 9.2E-43 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 PRINTS PR00738 Glycosyl hydrolase family 20 signature 139 160 9.2E-43 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 PRINTS PR00738 Glycosyl hydrolase family 20 signature 110 127 9.2E-43 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 PRINTS PR00738 Glycosyl hydrolase family 20 signature 421 437 9.2E-43 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 PRINTS PR00738 Glycosyl hydrolase family 20 signature 210 227 9.2E-43 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_30860 4a6f70cf2b5263f69707c86a0fbe57d0 522 PRINTS PR00738 Glycosyl hydrolase family 20 signature 67 87 9.2E-43 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_34830 97dc844c5533b62ef7ac2a4321d981f4 253 Gene3D G3DSA:3.20.20.370 1 248 1.7E-96 T 12-10-2018 AFR_34830 97dc844c5533b62ef7ac2a4321d981f4 253 SUPERFAMILY SSF88713 1 248 8.15E-96 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_34830 97dc844c5533b62ef7ac2a4321d981f4 253 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 243 42.455 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 AFR_34830 97dc844c5533b62ef7ac2a4321d981f4 253 Pfam PF03746 LamB/YcsF family 1 238 5.2E-98 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 AFR_28690 477f4fa4cc0ffaea7fbfceb8a375baa6 428 Pfam PF01936 NYN domain 5 172 1.5E-18 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type AFR_28690 477f4fa4cc0ffaea7fbfceb8a375baa6 428 Gene3D G3DSA:3.40.50.1010 3 177 1.3E-12 T 12-10-2018 AFR_20895 2e34235c7eacdf1c43c5d384ed2fa802 668 SUPERFAMILY SSF82866 98 322 4.84E-32 T 12-10-2018 AFR_20895 2e34235c7eacdf1c43c5d384ed2fa802 668 Gene3D G3DSA:1.20.1640.10 141 319 1.8E-8 T 12-10-2018 AFR_20895 2e34235c7eacdf1c43c5d384ed2fa802 668 SUPERFAMILY SSF82866 459 658 3.27E-24 T 12-10-2018 AFR_20895 2e34235c7eacdf1c43c5d384ed2fa802 668 Pfam PF03176 MMPL family 446 659 9.2E-42 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_20895 2e34235c7eacdf1c43c5d384ed2fa802 668 Pfam PF03176 MMPL family 38 353 3.7E-60 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_29840 040fd8cfb12f13809240a34a70572fa4 260 SUPERFAMILY SSF54001 73 147 2.66E-12 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_29840 040fd8cfb12f13809240a34a70572fa4 260 Pfam PF01841 Transglutaminase-like superfamily 80 135 1.3E-7 T 12-10-2018 IPR002931 Transglutaminase-like AFR_29840 040fd8cfb12f13809240a34a70572fa4 260 Gene3D G3DSA:3.10.620.30 67 144 4.1E-8 T 12-10-2018 AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 SMART SM00421 198 255 7.3E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 Pfam PF00196 Bacterial regulatory proteins, luxR family 200 253 1.1E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 SUPERFAMILY SSF46894 192 254 1.43E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 Gene3D G3DSA:1.10.10.10 132 261 1.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 215 8.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 231 8.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 231 243 8.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05880 9a7ce87b0d647d7a66e8683e673b62a1 263 ProSitePatterns PS00622 LuxR-type HTH domain signature. 215 242 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 Gene3D G3DSA:1.10.1660.10 1 116 1.6E-27 T 12-10-2018 AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 SUPERFAMILY SSF46955 4 102 2.49E-26 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 9.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 9.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 9.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 SMART SM00422 2 71 2.2E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33840 2b81e5310ac8740ee96bc2b5ce658e27 121 Pfam PF13411 MerR HTH family regulatory protein 3 67 5.2E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_18245 f4d19258627fa41c38ff0e8ade818fac 688 Gene3D G3DSA:1.10.390.60 455 661 1.1E-31 T 12-10-2018 AFR_18245 f4d19258627fa41c38ff0e8ade818fac 688 Gene3D G3DSA:2.60.40.1730 37 220 5.2E-24 T 12-10-2018 AFR_18245 f4d19258627fa41c38ff0e8ade818fac 688 Pfam PF05547 Immune inhibitor A peptidase M6 247 423 4.5E-8 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_18245 f4d19258627fa41c38ff0e8ade818fac 688 SUPERFAMILY SSF63737 26 220 1.09E-35 T 12-10-2018 AFR_18245 f4d19258627fa41c38ff0e8ade818fac 688 SUPERFAMILY SSF55486 455 668 8.06E-46 T 12-10-2018 AFR_18245 f4d19258627fa41c38ff0e8ade818fac 688 Pfam PF01433 Peptidase family M1 domain 515 657 1.6E-23 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_08450 aef66183ae4b861aef415dcb5fc01533 131 SUPERFAMILY SSF69754 22 114 1.44E-7 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFR_08450 aef66183ae4b861aef415dcb5fc01533 131 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 25 106 8.4E-6 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 AFR_08450 aef66183ae4b861aef415dcb5fc01533 131 Gene3D G3DSA:3.30.160.100 21 119 1.0E-6 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFR_40360 be7c425c35c1efa5b71ff3829c4541dc 243 Gene3D G3DSA:3.20.20.140 12 243 3.1E-17 T 12-10-2018 AFR_40360 be7c425c35c1efa5b71ff3829c4541dc 243 SUPERFAMILY SSF89550 17 240 1.57E-10 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 Pfam PF13424 Tetratricopeptide repeat 557 626 6.4E-15 T 12-10-2018 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 Pfam PF13424 Tetratricopeptide repeat 637 708 1.1E-15 T 12-10-2018 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SUPERFAMILY SSF52540 114 371 6.97E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SUPERFAMILY SSF48452 631 750 3.6E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 Gene3D G3DSA:1.25.40.10 484 768 1.3E-64 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 PRINTS PR00364 Disease resistance protein signature 308 322 2.4E-8 T 12-10-2018 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 PRINTS PR00364 Disease resistance protein signature 224 238 2.4E-8 T 12-10-2018 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 PRINTS PR00364 Disease resistance protein signature 142 157 2.4E-8 T 12-10-2018 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 Gene3D G3DSA:3.40.50.300 109 266 3.8E-22 T 12-10-2018 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SUPERFAMILY SSF48452 517 670 2.45E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SMART SM00028 677 710 1.1E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SMART SM00028 637 670 12.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SMART SM00028 597 630 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SMART SM00028 557 590 4.6E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 SMART SM00028 717 750 12.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 Pfam PF00931 NB-ARC domain 133 366 2.5E-10 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_15885 3584dd9fa4189d156c095d46ea82f739 768 Pfam PF13176 Tetratricopeptide repeat 720 753 0.0072 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 SMART SM00020 7 225 1.2E-32 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 171 183 2.8E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 31 46 2.8E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 84 98 2.8E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 Gene3D G3DSA:2.40.10.10 10 219 7.5E-44 T 12-10-2018 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 Pfam PF00089 Trypsin 8 204 1.2E-32 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 Gene3D G3DSA:2.40.10.10 20 220 7.5E-44 T 12-10-2018 AFR_13280 bb0cd82e4dd83610775492922d4fca92 237 SUPERFAMILY SSF50494 6 205 2.04E-43 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 69 250 23.021 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 PRINTS PR00338 Transcription termination factor NUSG signature 226 242 4.7E-18 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 PRINTS PR00338 Transcription termination factor NUSG signature 208 223 4.7E-18 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 PRINTS PR00338 Transcription termination factor NUSG signature 124 136 4.7E-18 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 SUPERFAMILY SSF82679 71 173 1.96E-33 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 Gene3D G3DSA:2.30.30.30 190 250 4.1E-24 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 Gene3D G3DSA:3.30.70.940 67 189 1.2E-37 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 SUPERFAMILY SSF50104 195 250 2.41E-16 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 SMART SM00738 69 180 3.5E-44 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 Pfam PF02357 Transcription termination factor nusG 71 174 2.8E-21 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 72 250 1.0E-59 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFR_04425 b1c3e880928af27fd8051cf32712cb3a 250 ProSitePatterns PS01014 Transcription termination factor nusG signature. 233 242 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site AFR_32210 dc19d0a77905e22474aa9659a80176e0 353 SUPERFAMILY SSF52540 51 317 4.14E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32210 dc19d0a77905e22474aa9659a80176e0 353 Gene3D G3DSA:3.40.50.300 54 230 7.7E-22 T 12-10-2018 AFR_32210 dc19d0a77905e22474aa9659a80176e0 353 Pfam PF07728 AAA domain (dynein-related subfamily) 73 211 1.3E-37 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFR_34825 f30b4370ff70727357297c4c0622aafd 407 Pfam PF01566 Natural resistance-associated macrophage protein 42 366 6.3E-17 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_13220 3db758f6d344cf967e62ce5a51972699 225 Gene3D G3DSA:1.10.357.10 5 219 4.2E-47 T 12-10-2018 AFR_13220 3db758f6d344cf967e62ce5a51972699 225 SUPERFAMILY SSF46689 10 83 9.75E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13220 3db758f6d344cf967e62ce5a51972699 225 Pfam PF13305 WHG domain 105 192 2.7E-15 T 12-10-2018 IPR025996 WHG domain AFR_13220 3db758f6d344cf967e62ce5a51972699 225 SUPERFAMILY SSF48498 102 211 4.56E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 SMART SM00448 5 118 6.5E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 Pfam PF00072 Response regulator receiver domain 7 118 6.0E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 SUPERFAMILY SSF52172 4 135 9.39E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 Gene3D G3DSA:3.40.50.12740 5 208 4.8E-69 T 12-10-2018 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 SUPERFAMILY SSF46894 132 209 4.42E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 1.9E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16790 e3eb7e9043246ec3085390abff345cf0 210 SMART SM00421 145 202 1.5E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16140 ae87f7f04bcdcbf95b6cdaf337475206 226 Pfam PF04234 CopC domain 26 142 3.7E-12 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 AFR_16140 ae87f7f04bcdcbf95b6cdaf337475206 226 Gene3D G3DSA:2.60.40.1220 25 143 2.8E-7 T 12-10-2018 AFR_16140 ae87f7f04bcdcbf95b6cdaf337475206 226 SUPERFAMILY SSF81296 25 143 6.16E-8 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 SUPERFAMILY SSF51735 2 223 1.12E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 118 146 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 2 222 2.5E-44 T 12-10-2018 AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 Gene3D G3DSA:3.40.50.720 9 223 7.7E-56 T 12-10-2018 AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 169 6.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 58 69 6.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 150 6.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 121 6.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 206 6.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 150 3.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 58 69 3.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07905 e91bd8468fb6400e0f98c524cd1871e6 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 119 3.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_41265 fbe836f13252bafc169166bd48005d3d 129 SUPERFAMILY SSF50475 5 127 1.96E-28 T 12-10-2018 AFR_41265 fbe836f13252bafc169166bd48005d3d 129 Gene3D G3DSA:2.30.110.10 2 128 1.8E-34 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_41265 fbe836f13252bafc169166bd48005d3d 129 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 127 1.5E-35 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_41265 fbe836f13252bafc169166bd48005d3d 129 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 90 5.0E-19 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_07365 d6e444c3cdb199d7f695e291244d90ab 350 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 14 347 3.0E-125 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFR_07365 d6e444c3cdb199d7f695e291244d90ab 350 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 12 349 35.376 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFR_07365 d6e444c3cdb199d7f695e291244d90ab 350 Pfam PF02277 Phosphoribosyltransferase 10 347 6.5E-127 T 12-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFR_07365 d6e444c3cdb199d7f695e291244d90ab 350 Gene3D G3DSA:1.10.1610.10 11 337 3.1E-127 T 12-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFR_07365 d6e444c3cdb199d7f695e291244d90ab 350 Gene3D G3DSA:3.40.50.10210 57 330 3.1E-127 T 12-10-2018 AFR_07365 d6e444c3cdb199d7f695e291244d90ab 350 SUPERFAMILY SSF52733 4 348 2.75E-113 T 12-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFR_06740 6b7ccff87821e5277c36f105b070f520 279 Gene3D G3DSA:1.10.1660.10 4 211 9.0E-21 T 12-10-2018 AFR_06740 6b7ccff87821e5277c36f105b070f520 279 Pfam PF13411 MerR HTH family regulatory protein 3 71 9.3E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_06740 6b7ccff87821e5277c36f105b070f520 279 SUPERFAMILY SSF46955 2 99 6.59E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_06740 6b7ccff87821e5277c36f105b070f520 279 SMART SM00422 2 72 3.8E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13050 9aa2b003cde2f1c1802cf22eb6aaa28c 289 Gene3D G3DSA:3.10.180.10 1 129 7.9E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_13050 9aa2b003cde2f1c1802cf22eb6aaa28c 289 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 141 251 2.0E-15 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_13050 9aa2b003cde2f1c1802cf22eb6aaa28c 289 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 2.1E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_13050 9aa2b003cde2f1c1802cf22eb6aaa28c 289 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 229 250 - T 12-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 AFR_13050 9aa2b003cde2f1c1802cf22eb6aaa28c 289 SUPERFAMILY SSF54593 2 129 1.51E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_13050 9aa2b003cde2f1c1802cf22eb6aaa28c 289 Gene3D G3DSA:3.10.180.10 136 283 1.0E-40 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_13050 9aa2b003cde2f1c1802cf22eb6aaa28c 289 SUPERFAMILY SSF54593 136 276 7.25E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 Gene3D G3DSA:1.10.10.1600 448 535 4.2E-23 T 12-10-2018 AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 Gene3D G3DSA:3.20.20.140 2 291 7.7E-90 T 12-10-2018 AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1057 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 Pfam PF02811 PHP domain 7 193 1.2E-44 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 315 755 2.5E-166 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 SMART SM00481 6 73 1.4E-30 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 Pfam PF14579 Helix-hairpin-helix motif 828 915 5.9E-25 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_10090 2b7afa01cf965fa9d3d9a8a44f1f0408 1178 SUPERFAMILY SSF89550 5 246 1.83E-29 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_33085 2c8879eba7d1b2e59e0d7011359a8411 285 SUPERFAMILY SSF140959 21 280 2.35E-97 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFR_33085 2c8879eba7d1b2e59e0d7011359a8411 285 Gene3D G3DSA:1.20.58.480 19 285 9.7E-98 T 12-10-2018 AFR_33085 2c8879eba7d1b2e59e0d7011359a8411 285 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 15 280 1.9E-119 T 12-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 AFR_33085 2c8879eba7d1b2e59e0d7011359a8411 285 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 15 280 38.756 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFR_33085 2c8879eba7d1b2e59e0d7011359a8411 285 Pfam PF03301 Tryptophan 2,3-dioxygenase 204 278 2.1E-21 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFR_33085 2c8879eba7d1b2e59e0d7011359a8411 285 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 143 5.8E-40 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 Gene3D G3DSA:2.60.120.10 10 277 9.5E-122 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 392 2.3E-66 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 SUPERFAMILY SSF51182 4 378 2.26E-87 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 Pfam PF01238 Phosphomannose isomerase type I 4 356 1.5E-62 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 Gene3D G3DSA:2.60.120.10 303 387 9.5E-122 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PIRSF PIRSF001480 1 395 6.3E-90 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 257 276 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 35 50 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 84 105 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 222 237 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 238 257 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 7 25 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 PRINTS PR00714 Phosphomannose isomerase type I signature 276 295 5.4E-59 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFR_05735 1edcf2f1e1a90fecf82a425ce312335c 396 Gene3D G3DSA:1.10.441.10 149 302 9.5E-122 T 12-10-2018 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 SMART SM00421 157 220 1.8E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 SUPERFAMILY SSF46894 142 205 2.14E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 SMART SM00448 10 129 8.9E-6 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 SUPERFAMILY SSF52172 8 140 7.54E-15 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28960 d244fcd6837f14780452deb3691c08e2 228 Gene3D G3DSA:3.40.50.12740 10 224 7.7E-39 T 12-10-2018 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 Pfam PF00072 Response regulator receiver domain 12 116 1.8E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 204 5.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 3.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 3.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28960 d244fcd6837f14780452deb3691c08e2 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 3.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 SUPERFAMILY SSF52540 144 345 5.69E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 Gene3D G3DSA:3.40.50.300 171 353 7.1E-36 T 12-10-2018 AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 SMART SM00490 423 500 1.7E-10 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 5.9E-12 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 540 1.5E-47 T 12-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 SUPERFAMILY SSF52540 290 513 8.36E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 Pfam PF13625 Helicase conserved C-terminal domain 6 134 8.4E-43 T 12-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 Gene3D G3DSA:3.40.50.300 354 545 1.2E-48 T 12-10-2018 AFR_02080 259c37c7fbd8db3afe8b6ba0d4089461 553 SMART SM00487 178 353 3.1E-20 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_13885 ea8502faa83c9b67e0ff8902730d1b5e 1048 Pfam PF05729 NACHT domain 254 420 2.1E-17 T 12-10-2018 IPR007111 NACHT nucleoside triphosphatase AFR_13885 ea8502faa83c9b67e0ff8902730d1b5e 1048 Gene3D G3DSA:3.90.1580.10 726 1048 2.3E-43 T 12-10-2018 AFR_13885 ea8502faa83c9b67e0ff8902730d1b5e 1048 Pfam PF13271 Domain of unknown function (DUF4062) 2 88 4.9E-11 T 12-10-2018 IPR025139 Domain of unknown function DUF4062 AFR_13885 ea8502faa83c9b67e0ff8902730d1b5e 1048 SUPERFAMILY SSF52540 237 411 4.86E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13885 ea8502faa83c9b67e0ff8902730d1b5e 1048 Pfam PF03781 Sulfatase-modifying factor enzyme 1 770 1043 1.3E-37 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFR_13885 ea8502faa83c9b67e0ff8902730d1b5e 1048 Gene3D G3DSA:3.40.50.300 229 385 1.3E-11 T 12-10-2018 AFR_13885 ea8502faa83c9b67e0ff8902730d1b5e 1048 SUPERFAMILY SSF56436 741 1044 5.42E-43 T 12-10-2018 IPR016187 C-type lectin fold AFR_34705 23ef3914eeca4ca291d7c55a66d8e7f1 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 288 5.7E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_34705 23ef3914eeca4ca291d7c55a66d8e7f1 302 Gene3D G3DSA:1.10.3720.10 47 298 7.1E-61 T 12-10-2018 IPR035906 MetI-like superfamily AFR_34705 23ef3914eeca4ca291d7c55a66d8e7f1 302 SUPERFAMILY SSF161098 53 288 1.13E-49 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 PRINTS PR00134 Glycosyl hydrolase family 10 signature 187 198 1.2E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 PRINTS PR00134 Glycosyl hydrolase family 10 signature 216 228 1.2E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 PRINTS PR00134 Glycosyl hydrolase family 10 signature 100 112 1.2E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 PRINTS PR00134 Glycosyl hydrolase family 10 signature 142 153 1.2E-16 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 SUPERFAMILY SSF51445 30 322 1.52E-107 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 Gene3D G3DSA:3.20.20.80 23 331 6.4E-115 T 12-10-2018 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 Pfam PF00553 Cellulose binding domain 351 440 1.0E-19 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 Pfam PF00331 Glycosyl hydrolase family 10 29 319 1.1E-103 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 SMART SM00633 69 321 4.8E-129 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 248 258 - T 12-10-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 SMART SM00637 351 441 9.6E-27 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 Gene3D G3DSA:2.60.40.290 346 444 8.2E-24 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_14910 32ee5435a6395eef7bbf675ea8fb5cec 444 SUPERFAMILY SSF49384 345 441 4.26E-23 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 Pfam PF14310 Fibronectin type III-like domain 708 775 1.4E-14 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 Gene3D G3DSA:2.60.120.260 374 519 1.1E-201 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 Gene3D G3DSA:3.40.50.1700 291 618 1.1E-201 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 Gene3D G3DSA:3.20.20.300 2 663 1.1E-201 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 32 271 2.4E-47 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 SMART SM01217 708 779 7.7E-14 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 SUPERFAMILY SSF51445 2 289 3.47E-88 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 Gene3D G3DSA:2.60.40.10 678 790 3.9E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 PRINTS PR00133 Glycosyl hydrolase family 3 signature 59 78 2.1E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 PRINTS PR00133 Glycosyl hydrolase family 3 signature 136 152 2.1E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 PRINTS PR00133 Glycosyl hydrolase family 3 signature 30 46 2.1E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 PRINTS PR00133 Glycosyl hydrolase family 3 signature 205 223 2.1E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 PRINTS PR00133 Glycosyl hydrolase family 3 signature 105 121 2.1E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 SUPERFAMILY SSF52279 309 682 1.44E-50 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_07935 8ee0d755c9196b03ed77645d6cb4733e 790 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 309 679 1.0E-57 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AFR_38525 ef857a443c339e4b79744590aec3a6bf 134 Pfam PF09394 Chagasin family peptidase inhibitor I42 33 118 1.4E-7 T 12-10-2018 IPR018990 Proteinase inhibitor I42, chagasin AFR_38525 ef857a443c339e4b79744590aec3a6bf 134 Gene3D G3DSA:2.60.40.2020 30 133 1.1E-6 T 12-10-2018 IPR036331 Chagasin-like superfamily AFR_38525 ef857a443c339e4b79744590aec3a6bf 134 SUPERFAMILY SSF141066 24 109 9.29E-6 T 12-10-2018 IPR036331 Chagasin-like superfamily AFR_22375 ae58caa24021163d2bacc82997346236 533 Gene3D G3DSA:3.10.105.10 281 500 2.9E-46 T 12-10-2018 AFR_22375 ae58caa24021163d2bacc82997346236 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 430 8.5E-83 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFR_22375 ae58caa24021163d2bacc82997346236 533 SUPERFAMILY SSF53850 31 531 3.38E-121 T 12-10-2018 AFR_22375 ae58caa24021163d2bacc82997346236 533 PIRSF PIRSF002741 2 533 1.1E-98 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFR_22375 ae58caa24021163d2bacc82997346236 533 Gene3D G3DSA:3.40.190.10 18 280 6.8E-65 T 12-10-2018 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Gene3D G3DSA:3.30.70.260 717 798 4.4E-17 T 12-10-2018 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 SUPERFAMILY SSF81271 449 520 2.4E-21 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Pfam PF13328 HD domain 98 245 1.7E-47 T 12-10-2018 IPR003607 HD/PDEase domain AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Gene3D G3DSA:1.10.3210.10 69 260 1.2E-76 T 12-10-2018 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 SMART SM00471 113 223 4.4E-10 T 12-10-2018 IPR003607 HD/PDEase domain AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Pfam PF13291 ACT domain 718 794 1.6E-16 T 12-10-2018 IPR002912 ACT domain AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Gene3D G3DSA:3.30.460.10 263 394 4.0E-49 T 12-10-2018 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 SUPERFAMILY SSF55021 719 796 6.66E-14 T 12-10-2018 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Pfam PF02824 TGS domain 461 520 5.1E-23 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 SUPERFAMILY SSF81301 250 465 7.68E-65 T 12-10-2018 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 98 793 1.7E-258 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Gene3D G3DSA:3.10.20.30 454 527 3.9E-31 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 SUPERFAMILY SSF109604 75 260 1.51E-69 T 12-10-2018 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 SMART SM00954 305 415 3.0E-68 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 AFR_31035 2f9ce5c9f8caf54bb8bea5352753ce4d 799 Pfam PF04607 Region found in RelA / SpoT proteins 305 415 1.7E-38 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 AFR_38590 7183e6eb54afcca7afa2a5aa08e2500e 96 SUPERFAMILY SSF46785 1 87 2.53E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_38590 7183e6eb54afcca7afa2a5aa08e2500e 96 Gene3D G3DSA:1.10.10.10 1 95 2.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38590 7183e6eb54afcca7afa2a5aa08e2500e 96 Pfam PF01022 Bacterial regulatory protein, arsR family 4 49 1.4E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_38590 7183e6eb54afcca7afa2a5aa08e2500e 96 SMART SM00418 1 75 2.2E-18 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Gene3D G3DSA:3.30.300.30 796 894 1.9E-12 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Gene3D G3DSA:1.10.1200.10 895 977 2.0E-23 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 SMART SM00823 Phosphopantetheine attachment site 907 975 8.4E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 SUPERFAMILY SSF52777 982 1186 7.67E-26 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Gene3D G3DSA:3.30.559.10 978 1156 2.1E-39 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 SUPERFAMILY SSF53335 510 663 2.03E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 SUPERFAMILY SSF52777 1172 1443 3.56E-32 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 56 456 2.2E-129 T 12-10-2018 IPR010071 Amino acid adenylation domain AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1310 1466 3.4E-39 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 SUPERFAMILY SSF47336 901 971 3.27E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Pfam PF00668 Condensation domain 1004 1446 6.4E-38 T 12-10-2018 IPR001242 Condensation domain AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Pfam PF00550 Phosphopantetheine attachment site 909 971 2.9E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Gene3D G3DSA:3.30.300.30 425 502 4.5E-18 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Gene3D G3DSA:3.40.50.12780 26 424 1.1E-140 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Gene3D G3DSA:3.30.559.30 1157 1444 9.8E-81 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Pfam PF13649 Methyltransferase domain 547 646 2.5E-11 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Pfam PF00501 AMP-binding enzyme 35 432 4.0E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 SUPERFAMILY SSF56801 26 920 2.62E-155 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Gene3D G3DSA:3.40.50.150 518 693 5.2E-34 T 12-10-2018 AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 484 1.3E-5 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_23680 8406d79fdf82cd27013085fb57dd8b37 1474 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 PRINTS PR00046 Major sigma-70 factor signature 49 62 2.9E-7 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 PRINTS PR00046 Major sigma-70 factor signature 211 226 2.9E-7 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 PRINTS PR00046 Major sigma-70 factor signature 194 206 2.9E-7 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Gene3D G3DSA:1.10.10.10 94 146 4.1E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 241 8.0E-33 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 SUPERFAMILY SSF88659 97 171 2.96E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Pfam PF13466 STAS domain 272 352 2.1E-13 T 12-10-2018 IPR002645 STAS domain AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 SUPERFAMILY SSF88946 16 93 6.15E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 259 357 8.5E-17 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 SUPERFAMILY SSF88659 160 243 2.24E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Pfam PF04542 Sigma-70 region 2 30 93 2.4E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Gene3D G3DSA:1.20.120.1810 4 92 1.5E-12 T 12-10-2018 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Gene3D G3DSA:3.30.750.24 258 358 1.6E-20 T 12-10-2018 IPR036513 STAS domain superfamily AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 SUPERFAMILY SSF52091 260 356 3.14E-18 T 12-10-2018 IPR036513 STAS domain superfamily AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Gene3D G3DSA:1.10.10.10 172 243 3.0E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Pfam PF04539 Sigma-70 region 3 111 170 7.0E-9 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_26805 b80d53e76ad648b67de8ec2b481e1b72 359 Pfam PF04545 Sigma-70, region 4 191 239 4.8E-15 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 SMART SM00448 1 116 7.4E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 Gene3D G3DSA:3.40.50.12740 1 213 4.5E-61 T 12-10-2018 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 Pfam PF00072 Response regulator receiver domain 1 117 2.6E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 SUPERFAMILY SSF46894 141 212 5.1E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.2E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 SUPERFAMILY SSF52172 1 126 2.42E-29 T 12-10-2018 IPR011006 CheY-like superfamily AFR_27215 0cc062818eadd2c4c89a54e70b19423d 227 SMART SM00421 150 207 9.0E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_37200 b32c448d99e0f8812d0f6d84d4e5e0d1 198 Gene3D G3DSA:1.10.10.10 3 103 3.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37200 b32c448d99e0f8812d0f6d84d4e5e0d1 198 SUPERFAMILY SSF46785 11 179 3.54E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_37200 b32c448d99e0f8812d0f6d84d4e5e0d1 198 Pfam PF03551 Transcriptional regulator PadR-like family 15 91 7.6E-11 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_31115 f0caac3f03150508a5d8c6b930cff0eb 210 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 72 94 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_31115 f0caac3f03150508a5d8c6b930cff0eb 210 Pfam PF01066 CDP-alcohol phosphatidyltransferase 29 94 3.7E-10 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_31115 f0caac3f03150508a5d8c6b930cff0eb 210 Gene3D G3DSA:1.20.120.1760 10 203 5.3E-56 T 12-10-2018 AFR_41435 81345618becbcef8b664f60200e7e031 338 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_41435 81345618becbcef8b664f60200e7e031 338 Pfam PF00005 ABC transporter 36 180 1.9E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_41435 81345618becbcef8b664f60200e7e031 338 SUPERFAMILY SSF52540 18 256 4.32E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41435 81345618becbcef8b664f60200e7e031 338 SMART SM00382 43 229 2.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41435 81345618becbcef8b664f60200e7e031 338 Gene3D G3DSA:3.40.50.300 16 273 5.8E-74 T 12-10-2018 AFR_41435 81345618becbcef8b664f60200e7e031 338 SUPERFAMILY SSF54631 257 331 6.68E-7 T 12-10-2018 AFR_31865 f4391d048067edda52f50a0fb4dbdf4c 761 Pfam PF13538 UvrD-like helicase C-terminal domain 700 746 2.6E-9 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain AFR_31865 f4391d048067edda52f50a0fb4dbdf4c 761 Gene3D G3DSA:3.40.50.300 600 761 5.1E-15 T 12-10-2018 AFR_31865 f4391d048067edda52f50a0fb4dbdf4c 761 SUPERFAMILY SSF52540 173 751 4.71E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31865 f4391d048067edda52f50a0fb4dbdf4c 761 Gene3D G3DSA:3.40.50.300 412 599 1.1E-6 T 12-10-2018 AFR_31865 f4391d048067edda52f50a0fb4dbdf4c 761 Pfam PF13245 AAA domain 186 570 1.1E-11 T 12-10-2018 AFR_31865 f4391d048067edda52f50a0fb4dbdf4c 761 Gene3D G3DSA:3.40.50.300 173 399 2.6E-9 T 12-10-2018 AFR_01255 376a480fa108d744aa753b52635b9171 695 Pfam PF00326 Prolyl oligopeptidase family 477 692 3.2E-63 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AFR_01255 376a480fa108d744aa753b52635b9171 695 SUPERFAMILY SSF50993 5 425 7.06E-95 T 12-10-2018 AFR_01255 376a480fa108d744aa753b52635b9171 695 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 523 553 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 AFR_01255 376a480fa108d744aa753b52635b9171 695 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 10 417 1.5E-107 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 AFR_01255 376a480fa108d744aa753b52635b9171 695 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 546 566 1.1E-52 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_01255 376a480fa108d744aa753b52635b9171 695 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 488 512 1.1E-52 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_01255 376a480fa108d744aa753b52635b9171 695 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 462 480 1.1E-52 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_01255 376a480fa108d744aa753b52635b9171 695 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 605 620 1.1E-52 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_01255 376a480fa108d744aa753b52635b9171 695 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 516 535 1.1E-52 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_01255 376a480fa108d744aa753b52635b9171 695 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 623 645 1.1E-52 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_01255 376a480fa108d744aa753b52635b9171 695 Gene3D G3DSA:2.130.10.120 77 420 2.5E-271 T 12-10-2018 AFR_01255 376a480fa108d744aa753b52635b9171 695 SUPERFAMILY SSF53474 434 672 2.82E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01255 376a480fa108d744aa753b52635b9171 695 Gene3D G3DSA:3.40.50.1820 28 688 2.5E-271 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 169 0.0098 T 12-10-2018 AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 SUPERFAMILY SSF51735 1 241 1.1E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 Pfam PF00106 short chain dehydrogenase 4 183 1.5E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 1.8E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 Gene3D G3DSA:3.40.50.720 1 247 9.8E-67 T 12-10-2018 AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 3.3E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 3.3E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 3.3E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.3E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23860 2d735b4b9ce85c5c74800b9898fe506c 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 3.3E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_26595 f0c8f8bd3a226aa81de54efb8f0e80c5 246 Pfam PF00005 ABC transporter 24 170 5.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_26595 f0c8f8bd3a226aa81de54efb8f0e80c5 246 Gene3D G3DSA:3.40.50.300 6 242 3.5E-71 T 12-10-2018 AFR_26595 f0c8f8bd3a226aa81de54efb8f0e80c5 246 SUPERFAMILY SSF52540 7 222 2.37E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26595 f0c8f8bd3a226aa81de54efb8f0e80c5 246 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_26595 f0c8f8bd3a226aa81de54efb8f0e80c5 246 SMART SM00382 33 219 1.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_12550 119936f7d2977be8248f69f2a1814225 665 SUPERFAMILY SSF53474 93 469 5.46E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12550 119936f7d2977be8248f69f2a1814225 665 Pfam PF00561 alpha/beta hydrolase fold 105 242 9.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 9.7E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 Pfam PF00072 Response regulator receiver domain 14 125 9.8E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 SMART SM00448 12 125 1.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 SMART SM00421 163 220 1.4E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 Gene3D G3DSA:3.40.50.12740 12 223 1.4E-65 T 12-10-2018 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 SUPERFAMILY SSF52172 11 189 3.7E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 5.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 5.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33030 7a5132d2a5fbf4d63677086551814a74 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 5.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02850 5f5ff8a28c39c1ddae7bf37b07529982 241 Pfam PF13828 Domain of unknown function (DUF4190) 54 105 1.5E-12 T 12-10-2018 IPR025241 Domain of unknown function DUF4190 AFR_02850 5f5ff8a28c39c1ddae7bf37b07529982 241 Pfam PF13845 Septum formation 134 204 5.1E-8 T 12-10-2018 IPR026004 Septum formation-related domain AFR_31085 0a57f57dfb3139c99d5ad09306d12bea 205 Gene3D G3DSA:3.40.50.880 2 204 1.8E-73 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_31085 0a57f57dfb3139c99d5ad09306d12bea 205 SUPERFAMILY SSF52317 5 199 1.45E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_31085 0a57f57dfb3139c99d5ad09306d12bea 205 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 6 195 4.1E-72 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31085 0a57f57dfb3139c99d5ad09306d12bea 205 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 6 196 37.788 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31085 0a57f57dfb3139c99d5ad09306d12bea 205 Pfam PF01174 SNO glutamine amidotransferase family 8 197 2.0E-57 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31085 0a57f57dfb3139c99d5ad09306d12bea 205 PIRSF PIRSF005639 1 201 7.3E-72 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31085 0a57f57dfb3139c99d5ad09306d12bea 205 ProSitePatterns PS01236 PdxT/SNO family family signature. 43 53 - T 12-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_37785 1fac09aebbdb32917318931fb99fd141 252 SUPERFAMILY SSF51735 6 249 1.17E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37785 1fac09aebbdb32917318931fb99fd141 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 184 3.7E-6 T 12-10-2018 AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37785 1fac09aebbdb32917318931fb99fd141 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_37785 1fac09aebbdb32917318931fb99fd141 252 Gene3D G3DSA:3.40.50.720 4 251 2.7E-76 T 12-10-2018 AFR_37785 1fac09aebbdb32917318931fb99fd141 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 2.6E-60 T 12-10-2018 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Pfam PF01627 Hpt domain 6 96 1.9E-11 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Gene3D G3DSA:1.20.120.160 3 139 1.3E-18 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Gene3D G3DSA:3.30.565.10 266 453 3.1E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SUPERFAMILY SSF55874 270 452 1.19E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SMART SM00448 606 720 2.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SMART SM00260 446 586 6.1E-5 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Gene3D G3DSA:2.40.50.180 477 541 7.7E-14 T 12-10-2018 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 453 6.3E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SUPERFAMILY SSF50341 457 586 2.35E-15 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SUPERFAMILY SSF47226 3 109 1.44E-17 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Gene3D G3DSA:2.30.30.40 457 581 7.7E-14 T 12-10-2018 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SMART SM00073 1 98 5.8E-12 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Pfam PF00072 Response regulator receiver domain 608 720 1.6E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Gene3D G3DSA:3.40.50.12740 606 726 2.2E-35 T 12-10-2018 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 6.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 6.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 6.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 Pfam PF01584 CheW-like domain 459 588 1.6E-11 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SUPERFAMILY SSF52172 605 724 1.39E-31 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25685 ecc1fa89e2bccb2aba42fc9472a49ec0 726 SMART SM00387 312 454 4.9E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11865 e113acd3ef67f5014b2503668480a2fd 317 SMART SM00342 225 310 6.9E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_11865 e113acd3ef67f5014b2503668480a2fd 317 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 306 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_11865 e113acd3ef67f5014b2503668480a2fd 317 Pfam PF12833 Helix-turn-helix domain 231 311 1.8E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_11865 e113acd3ef67f5014b2503668480a2fd 317 SUPERFAMILY SSF46689 259 310 7.17E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_11865 e113acd3ef67f5014b2503668480a2fd 317 Gene3D G3DSA:1.10.10.60 203 314 1.6E-24 T 12-10-2018 AFR_05515 25d14938277569eb7575a985d90a11db 407 Gene3D G3DSA:3.40.50.1100 53 149 2.9E-114 T 12-10-2018 AFR_05515 25d14938277569eb7575a985d90a11db 407 Gene3D G3DSA:3.40.50.1100 10 309 2.9E-114 T 12-10-2018 AFR_05515 25d14938277569eb7575a985d90a11db 407 SUPERFAMILY SSF53686 6 312 9.95E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_05515 25d14938277569eb7575a985d90a11db 407 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 305 1.5E-86 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_05515 25d14938277569eb7575a985d90a11db 407 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 24 401 5.1E-135 T 12-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFR_30075 05f414d37e4e506b4770af24f1296cc7 121 SUPERFAMILY SSF54427 10 117 6.59E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_30075 05f414d37e4e506b4770af24f1296cc7 121 Gene3D G3DSA:3.10.450.50 6 119 4.4E-16 T 12-10-2018 AFR_30075 05f414d37e4e506b4770af24f1296cc7 121 Pfam PF12680 SnoaL-like domain 14 115 3.0E-13 T 12-10-2018 IPR037401 SnoaL-like domain AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 22 193 1.7E-24 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 Gene3D G3DSA:3.40.1440.10 213 311 6.3E-22 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 SUPERFAMILY SSF53098 22 206 2.94E-52 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 SMART SM00479 26 194 8.3E-47 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 SMART SM00465 227 308 1.1E-7 T 12-10-2018 IPR000305 GIY-YIG endonuclease AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 Pfam PF00929 Exonuclease 28 185 7.1E-31 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 Gene3D G3DSA:3.30.420.10 19 193 8.8E-50 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_09470 6dc023a29dc17b3c8051930c7ecf16b0 593 SUPERFAMILY SSF82771 227 305 2.75E-11 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFR_42075 b101c0192b49162c208c5aa83506ec94 296 SUPERFAMILY SSF47413 17 75 6.82E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_42075 b101c0192b49162c208c5aa83506ec94 296 SMART SM00530 24 79 0.0078 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_42075 b101c0192b49162c208c5aa83506ec94 296 Gene3D G3DSA:1.10.260.40 17 77 1.5E-5 T 12-10-2018 AFR_42075 b101c0192b49162c208c5aa83506ec94 296 Pfam PF13560 Helix-turn-helix domain 21 83 1.2E-12 T 12-10-2018 AFR_17120 6a9fba8b629abe1d94e4d795d87d716d 297 SUPERFAMILY SSF51735 7 245 3.74E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17120 6a9fba8b629abe1d94e4d795d87d716d 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17120 6a9fba8b629abe1d94e4d795d87d716d 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17120 6a9fba8b629abe1d94e4d795d87d716d 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17120 6a9fba8b629abe1d94e4d795d87d716d 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17120 6a9fba8b629abe1d94e4d795d87d716d 297 Gene3D G3DSA:3.40.50.720 4 295 3.9E-68 T 12-10-2018 AFR_17120 6a9fba8b629abe1d94e4d795d87d716d 297 Pfam PF00106 short chain dehydrogenase 8 207 3.6E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 3.8E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 3.8E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 3.8E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 3.8E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 Gene3D G3DSA:1.10.287.130 254 327 6.9E-14 T 12-10-2018 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 SMART SM00388 261 329 5.0E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 SUPERFAMILY SSF47384 249 323 1.04E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 176 221 2.3E-6 T 12-10-2018 IPR000014 PAS domain AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 Gene3D G3DSA:3.30.565.10 336 483 1.4E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 SUPERFAMILY SSF55785 171 218 1.26E-9 T 12-10-2018 IPR035965 PAS domain superfamily AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 SUPERFAMILY SSF55874 332 483 2.75E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 Pfam PF00989 PAS fold 171 210 6.4E-6 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 SMART SM00387 373 484 4.2E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 483 6.5E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 328 2.1E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 SMART SM00091 165 230 0.004 T 12-10-2018 IPR000014 PAS domain AFR_42525 49e8b1e124450ccde3584aef3a185e0e 484 Gene3D G3DSA:3.30.450.20 167 225 1.7E-7 T 12-10-2018 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 SMART SM00387 337 448 1.4E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 446 6.3E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 SMART SM00388 224 292 1.1E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 SUPERFAMILY SSF55874 281 446 6.68E-47 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 292 4.4E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 Gene3D G3DSA:3.30.565.10 291 447 1.9E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 SUPERFAMILY SSF47384 207 293 7.85E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 445 1.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 401 1.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 1.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 1.0E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01230 655dc346fb9fa3245d42ed6c2fd023f4 448 Gene3D G3DSA:1.10.287.130 188 290 1.5E-23 T 12-10-2018 AFR_06145 71d633825dbc4cd68a0325712dc42ada 269 Gene3D G3DSA:3.40.50.200 1 226 1.4E-55 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_06145 71d633825dbc4cd68a0325712dc42ada 269 Pfam PF00082 Subtilase family 1 199 3.3E-33 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_06145 71d633825dbc4cd68a0325712dc42ada 269 SUPERFAMILY SSF52743 1 213 4.45E-54 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_42575 ca5b8ce4bbf8ce73d6083008b72420c0 117 Gene3D G3DSA:3.30.2010.20 2 116 6.2E-40 T 12-10-2018 IPR038555 Zincin-like metallopeptidase superfamily AFR_42575 ca5b8ce4bbf8ce73d6083008b72420c0 117 Pfam PF06262 Zincin-like metallopeptidase 29 116 2.4E-30 T 12-10-2018 IPR010428 Zincin-like metallopeptidase AFR_42575 ca5b8ce4bbf8ce73d6083008b72420c0 117 SUPERFAMILY SSF55486 4 116 4.4E-38 T 12-10-2018 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 Gene3D G3DSA:1.20.140.10 238 384 3.3E-54 T 12-10-2018 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 SUPERFAMILY SSF47203 230 383 2.74E-57 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 382 2.4E-48 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 Gene3D G3DSA:2.40.110.10 125 237 1.4E-42 T 12-10-2018 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 220 1.2E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 Gene3D G3DSA:1.10.540.10 12 123 1.4E-35 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 121 2.3E-28 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 SUPERFAMILY SSF56645 8 244 1.27E-79 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 PIRSF PIRSF016578 5 384 1.0E-20 T 12-10-2018 AFR_05570 0622df64add9894f0dd5f6870a223cd2 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_16035 57c4283b9aea172659cd9f3b1d322d6d 324 Gene3D G3DSA:3.40.50.720 3 304 2.2E-116 T 12-10-2018 AFR_16035 57c4283b9aea172659cd9f3b1d322d6d 324 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 5.1E-78 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_16035 57c4283b9aea172659cd9f3b1d322d6d 324 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_16035 57c4283b9aea172659cd9f3b1d322d6d 324 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 319 4.2E-124 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AFR_16035 57c4283b9aea172659cd9f3b1d322d6d 324 Gene3D G3DSA:3.90.25.10 191 312 2.2E-116 T 12-10-2018 AFR_16035 57c4283b9aea172659cd9f3b1d322d6d 324 SUPERFAMILY SSF51735 3 319 8.82E-98 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_34030 e11b25741cd353375deec530ff1165c3 118 SUPERFAMILY SSF56349 49 98 6.47E-12 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_34030 e11b25741cd353375deec530ff1165c3 118 Pfam PF00589 Phage integrase family 51 95 1.5E-8 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_34030 e11b25741cd353375deec530ff1165c3 118 Gene3D G3DSA:1.10.443.10 12 104 2.6E-11 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_38450 304113f5fa88e4b8bf8c42ba7afa150d 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 306 1.1E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_38450 304113f5fa88e4b8bf8c42ba7afa150d 314 SUPERFAMILY SSF161098 109 298 1.96E-24 T 12-10-2018 IPR035906 MetI-like superfamily AFR_38450 304113f5fa88e4b8bf8c42ba7afa150d 314 Gene3D G3DSA:1.10.3720.10 107 305 6.0E-19 T 12-10-2018 IPR035906 MetI-like superfamily AFR_31775 b93af0492c5a11d0198b6556ab59c133 226 Gene3D G3DSA:1.10.357.10 8 225 4.7E-55 T 12-10-2018 AFR_31775 b93af0492c5a11d0198b6556ab59c133 226 SUPERFAMILY SSF46689 15 79 2.44E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_31775 b93af0492c5a11d0198b6556ab59c133 226 SUPERFAMILY SSF48498 87 225 8.89E-20 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_31775 b93af0492c5a11d0198b6556ab59c133 226 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 81 221 2.0E-16 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_31775 b93af0492c5a11d0198b6556ab59c133 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 70 4.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 SUPERFAMILY SSF56420 1 141 1.2E-47 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 Pfam PF01327 Polypeptide deformylase 3 136 1.6E-40 T 12-10-2018 IPR023635 Peptide deformylase AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 PIRSF PIRSF004749 1 147 1.4E-41 T 12-10-2018 IPR023635 Peptide deformylase AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 1 142 2.0E-39 T 12-10-2018 IPR023635 Peptide deformylase AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 Gene3D G3DSA:3.90.45.10 1 151 9.3E-49 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 PRINTS PR01576 Peptide deformylase signature 85 103 9.1E-34 T 12-10-2018 IPR023635 Peptide deformylase AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 PRINTS PR01576 Peptide deformylase signature 73 84 9.1E-34 T 12-10-2018 IPR023635 Peptide deformylase AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 PRINTS PR01576 Peptide deformylase signature 13 42 9.1E-34 T 12-10-2018 IPR023635 Peptide deformylase AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 PRINTS PR01576 Peptide deformylase signature 104 133 9.1E-34 T 12-10-2018 IPR023635 Peptide deformylase AFR_03385 0b157224bfd38fbb8a5876f50565532f 154 Hamap MF_00163 Peptide deformylase [def]. 2 146 21.954 T 12-10-2018 IPR023635 Peptide deformylase AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 932 25.102 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 SUPERFAMILY SSF53383 457 927 1.07E-97 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 Gene3D G3DSA:3.90.1150.10 741 879 1.1E-38 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 6 926 0.0 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 Gene3D G3DSA:3.40.640.10 503 729 5.2E-58 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 Gene3D G3DSA:3.40.640.10 84 344 3.3E-104 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 Pfam PF02347 Glycine cleavage system P-protein 457 714 9.5E-11 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 Pfam PF02347 Glycine cleavage system P-protein 6 430 1.0E-178 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFR_21195 c8ec4aa6685a6dd36d82077d3e1ae56c 934 SUPERFAMILY SSF53383 6 431 8.69E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_40245 cee8169c2c5fea1cc390e54e5630a7e8 281 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 11 245 3.0E-79 T 12-10-2018 AFR_05455 99cdeb8efd9646fecff26584571d431b 324 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 68 292 4.0E-101 T 12-10-2018 IPR022488 Polyphosphate kinase-2-related AFR_05455 99cdeb8efd9646fecff26584571d431b 324 SUPERFAMILY SSF52540 97 285 1.31E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05455 99cdeb8efd9646fecff26584571d431b 324 Gene3D G3DSA:3.40.50.300 31 314 1.9E-99 T 12-10-2018 AFR_05455 99cdeb8efd9646fecff26584571d431b 324 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 66 292 1.4E-113 T 12-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 AFR_05455 99cdeb8efd9646fecff26584571d431b 324 PIRSF PIRSF028756 39 318 2.9E-117 T 12-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 AFR_30345 0b47878c2ac1b689e74389797206c599 235 Pfam PF08445 FR47-like protein 155 226 4.6E-10 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_30345 0b47878c2ac1b689e74389797206c599 235 Gene3D G3DSA:3.40.630.30 17 234 1.2E-22 T 12-10-2018 AFR_30345 0b47878c2ac1b689e74389797206c599 235 SUPERFAMILY SSF55729 114 227 1.17E-13 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 Gene3D G3DSA:3.40.50.300 3 287 4.4E-41 T 12-10-2018 AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 Pfam PF00005 ABC transporter 348 493 2.8E-12 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 SUPERFAMILY SSF52540 338 544 1.66E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 Pfam PF00005 ABC transporter 22 192 1.9E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 SMART SM00382 29 237 5.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 SMART SM00382 353 539 5.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 SUPERFAMILY SSF52540 11 240 6.45E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04680 75f17444b656b15d7ca798ff6a159ead 551 Gene3D G3DSA:3.40.50.300 327 550 1.4E-30 T 12-10-2018 AFR_24475 11d5c3a55b373d828da8308e74c3ada7 377 Pfam PF13556 PucR C-terminal helix-turn-helix domain 320 375 4.0E-19 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFR_24475 11d5c3a55b373d828da8308e74c3ada7 377 Gene3D G3DSA:1.10.10.2840 254 377 1.1E-17 T 12-10-2018 AFR_05500 73ffda287e152d36ac84d1af3f07f5d6 137 Pfam PF01230 HIT domain 14 105 2.0E-18 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_05500 73ffda287e152d36ac84d1af3f07f5d6 137 Gene3D G3DSA:3.30.428.10 1 136 4.8E-32 T 12-10-2018 IPR036265 HIT-like superfamily AFR_05500 73ffda287e152d36ac84d1af3f07f5d6 137 PRINTS PR00332 Histidine triad family signature 91 101 7.0E-12 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_05500 73ffda287e152d36ac84d1af3f07f5d6 137 PRINTS PR00332 Histidine triad family signature 26 44 7.0E-12 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_05500 73ffda287e152d36ac84d1af3f07f5d6 137 PRINTS PR00332 Histidine triad family signature 5 21 7.0E-12 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFR_05500 73ffda287e152d36ac84d1af3f07f5d6 137 SUPERFAMILY SSF54197 2 124 6.81E-32 T 12-10-2018 IPR036265 HIT-like superfamily AFR_31065 7276ec644f34363ef92624e77492aa8f 200 SUPERFAMILY SSF50249 1 62 6.28E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_31065 7276ec644f34363ef92624e77492aa8f 200 SUPERFAMILY SSF47781 65 131 6.39E-19 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_31065 7276ec644f34363ef92624e77492aa8f 200 Gene3D G3DSA:2.40.50.140 1 65 2.3E-23 T 12-10-2018 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 Gene3D G3DSA:1.10.150.20 66 140 5.0E-22 T 12-10-2018 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 SUPERFAMILY SSF46929 148 198 1.7E-7 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily AFR_31065 7276ec644f34363ef92624e77492aa8f 200 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.1E-15 T 12-10-2018 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 SMART SM00278 72 91 27.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 SMART SM00278 107 126 0.59 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 181 1.8E-36 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 197 26.939 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 Pfam PF07499 RuvA, C-terminal domain 149 197 3.2E-8 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 Pfam PF01330 RuvA N terminal domain 1 61 7.3E-18 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFR_31065 7276ec644f34363ef92624e77492aa8f 200 Gene3D G3DSA:1.10.8.10 141 200 2.3E-13 T 12-10-2018 AFR_18525 fad96e52d37c464704d49c18031cfdea 512 Gene3D G3DSA:2.40.110.10 110 224 1.6E-26 T 12-10-2018 AFR_18525 fad96e52d37c464704d49c18031cfdea 512 Gene3D G3DSA:1.20.140.10 225 373 9.9E-26 T 12-10-2018 AFR_18525 fad96e52d37c464704d49c18031cfdea 512 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 220 369 3.3E-20 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_18525 fad96e52d37c464704d49c18031cfdea 512 SUPERFAMILY SSF47203 220 374 4.03E-23 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_18525 fad96e52d37c464704d49c18031cfdea 512 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 111 207 4.6E-16 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_18525 fad96e52d37c464704d49c18031cfdea 512 SUPERFAMILY SSF56645 16 229 2.36E-41 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_18525 fad96e52d37c464704d49c18031cfdea 512 Gene3D G3DSA:1.10.540.10 11 107 9.8E-11 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 Gene3D G3DSA:1.25.40.10 635 973 1.1E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 90 3.9E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 SUPERFAMILY SSF46894 4 90 7.09E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 SUPERFAMILY SSF52540 267 528 1.98E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 SUPERFAMILY SSF48452 724 843 7.59E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 SMART SM01043 95 240 1.4E-41 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 Gene3D G3DSA:1.10.10.10 1 91 3.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 Gene3D G3DSA:1.25.40.10 94 260 5.0E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 SMART SM00862 16 90 2.2E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 SUPERFAMILY SSF48452 94 261 1.85E-37 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_35775 0ef890320b692eb8c0536f62fbc98032 974 Pfam PF03704 Bacterial transcriptional activator domain 95 240 7.9E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_40780 9fcabd5608a33f53e79e4237795d47a6 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 2.5E-114 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 AFR_40780 9fcabd5608a33f53e79e4237795d47a6 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_40780 9fcabd5608a33f53e79e4237795d47a6 258 SMART SM00382 29 245 1.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_40780 9fcabd5608a33f53e79e4237795d47a6 258 Pfam PF00005 ABC transporter 21 176 5.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_40780 9fcabd5608a33f53e79e4237795d47a6 258 SUPERFAMILY SSF52540 5 245 2.3E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40780 9fcabd5608a33f53e79e4237795d47a6 258 Gene3D G3DSA:3.40.50.300 2 256 5.2E-62 T 12-10-2018 AFR_20695 fe406b4fc2f20513b951bbfe4ebcfe6c 291 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 17 268 3.5E-93 T 12-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 AFR_20695 fe406b4fc2f20513b951bbfe4ebcfe6c 291 Gene3D G3DSA:2.60.120.10 124 267 2.7E-85 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_20695 fe406b4fc2f20513b951bbfe4ebcfe6c 291 PIRSF PIRSF036628 6 273 4.5E-91 T 12-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 AFR_20695 fe406b4fc2f20513b951bbfe4ebcfe6c 291 Gene3D G3DSA:2.60.120.10 18 123 2.7E-85 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_20695 fe406b4fc2f20513b951bbfe4ebcfe6c 291 SUPERFAMILY SSF51182 10 256 7.33E-61 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_20695 fe406b4fc2f20513b951bbfe4ebcfe6c 291 Pfam PF04962 KduI/IolB family 14 267 4.5E-89 T 12-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 AFR_39855 39ac2d412609203965214f02b8985b61 407 Pfam PF01590 GAF domain 30 155 3.3E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_39855 39ac2d412609203965214f02b8985b61 407 SUPERFAMILY SSF55781 28 166 1.98E-26 T 12-10-2018 AFR_39855 39ac2d412609203965214f02b8985b61 407 SUPERFAMILY SSF55874 237 399 1.24E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_39855 39ac2d412609203965214f02b8985b61 407 SMART SM00387 292 401 9.2E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_39855 39ac2d412609203965214f02b8985b61 407 Gene3D G3DSA:3.30.450.40 8 168 5.5E-19 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_39855 39ac2d412609203965214f02b8985b61 407 Gene3D G3DSA:3.30.565.10 224 396 2.8E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_39855 39ac2d412609203965214f02b8985b61 407 SMART SM00065 25 167 1.5E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 Gene3D G3DSA:3.40.50.620 378 524 3.4E-11 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 Pfam PF00582 Universal stress protein family 389 524 2.0E-7 T 12-10-2018 IPR006016 UspA AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 Pfam PF07690 Major Facilitator Superfamily 2 215 2.1E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 Pfam PF07690 Major Facilitator Superfamily 221 360 5.0E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 PRINTS PR01035 Tetracycline resistance protein signature 7 23 9.2E-11 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 PRINTS PR01035 Tetracycline resistance protein signature 149 169 9.2E-11 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 PRINTS PR01035 Tetracycline resistance protein signature 121 143 9.2E-11 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 SUPERFAMILY SSF52402 389 525 1.17E-10 T 12-10-2018 AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 SUPERFAMILY SSF103473 2 362 1.96E-54 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_40760 cfd3afadb13f3305a58e0888175bffc0 544 Gene3D G3DSA:1.20.1250.20 1 363 5.0E-51 T 12-10-2018 AFR_42300 f69e256c523a02c586de378660ae40be 617 Gene3D G3DSA:2.60.40.1180 58 478 1.1E-123 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_42300 f69e256c523a02c586de378660ae40be 617 Pfam PF00652 Ricin-type beta-trefoil lectin domain 493 613 7.1E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_42300 f69e256c523a02c586de378660ae40be 617 Gene3D G3DSA:2.80.10.50 486 583 8.4E-30 T 12-10-2018 AFR_42300 f69e256c523a02c586de378660ae40be 617 SUPERFAMILY SSF51011 412 478 2.37E-6 T 12-10-2018 AFR_42300 f69e256c523a02c586de378660ae40be 617 SMART SM00458 487 616 7.0E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_42300 f69e256c523a02c586de378660ae40be 617 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 417 476 5.4E-14 T 12-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_42300 f69e256c523a02c586de378660ae40be 617 Gene3D G3DSA:2.80.10.50 584 617 6.8E-11 T 12-10-2018 AFR_42300 f69e256c523a02c586de378660ae40be 617 PRINTS PR00843 Glycosyl hydrolase family 30 signature 270 292 5.2E-7 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_42300 f69e256c523a02c586de378660ae40be 617 PRINTS PR00843 Glycosyl hydrolase family 30 signature 73 93 5.2E-7 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_42300 f69e256c523a02c586de378660ae40be 617 PRINTS PR00843 Glycosyl hydrolase family 30 signature 202 219 5.2E-7 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_42300 f69e256c523a02c586de378660ae40be 617 SUPERFAMILY SSF50370 490 615 7.26E-39 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_42300 f69e256c523a02c586de378660ae40be 617 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 84 375 2.2E-31 T 12-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_42300 f69e256c523a02c586de378660ae40be 617 Gene3D G3DSA:3.20.20.80 81 418 1.1E-123 T 12-10-2018 AFR_42300 f69e256c523a02c586de378660ae40be 617 SUPERFAMILY SSF51445 83 418 8.73E-63 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 334 488 1.2E-23 T 12-10-2018 IPR000160 GGDEF domain AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 SUPERFAMILY SSF141868 505 753 2.48E-82 T 12-10-2018 IPR035919 EAL domain superfamily AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 Pfam PF00563 EAL domain 505 742 2.6E-69 T 12-10-2018 IPR001633 EAL domain AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 SUPERFAMILY SSF55073 340 491 1.8E-34 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 SMART SM00052 499 747 2.5E-105 T 12-10-2018 IPR001633 EAL domain AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 SMART SM00267 324 489 9.3E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 Pfam PF00990 Diguanylate cyclase, GGDEF domain 336 485 1.9E-30 T 12-10-2018 IPR000160 GGDEF domain AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 Gene3D G3DSA:3.20.20.450 504 756 1.1E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_34155 84b1fdfb29fd57b3c97d1069a865c7a8 762 Gene3D G3DSA:3.30.70.270 332 503 1.0E-41 T 12-10-2018 AFR_30780 73f233f4368b83700b074bb79b6eb4d3 220 SUPERFAMILY SSF52172 1 173 9.53E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_30780 73f233f4368b83700b074bb79b6eb4d3 220 Pfam PF00072 Response regulator receiver domain 3 113 4.6E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30780 73f233f4368b83700b074bb79b6eb4d3 220 Gene3D G3DSA:3.40.50.2300 1 120 1.8E-30 T 12-10-2018 AFR_30780 73f233f4368b83700b074bb79b6eb4d3 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 1.8E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_30780 73f233f4368b83700b074bb79b6eb4d3 220 Gene3D G3DSA:1.10.10.10 121 218 8.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30780 73f233f4368b83700b074bb79b6eb4d3 220 SMART SM00448 1 112 3.0E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30780 73f233f4368b83700b074bb79b6eb4d3 220 SMART SM00862 145 217 1.9E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_24390 4dad1006715fcdb68f7a4d45c21eba09 581 Gene3D G3DSA:1.10.3720.10 303 568 3.8E-45 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24390 4dad1006715fcdb68f7a4d45c21eba09 581 Gene3D G3DSA:1.10.3720.10 25 287 8.5E-47 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24390 4dad1006715fcdb68f7a4d45c21eba09 581 SUPERFAMILY SSF161098 300 562 7.01E-40 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24390 4dad1006715fcdb68f7a4d45c21eba09 581 SUPERFAMILY SSF161098 23 283 1.83E-40 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24390 4dad1006715fcdb68f7a4d45c21eba09 581 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 371 561 2.9E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_24390 4dad1006715fcdb68f7a4d45c21eba09 581 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 276 7.2E-9 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_38990 f6362202b85074f278cd1f5a7eb8b418 511 Gene3D G3DSA:3.30.300.310 412 511 2.0E-31 T 12-10-2018 AFR_38990 f6362202b85074f278cd1f5a7eb8b418 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 499 2.7E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_38990 f6362202b85074f278cd1f5a7eb8b418 511 Pfam PF00501 AMP-binding enzyme 12 416 1.0E-107 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_38990 f6362202b85074f278cd1f5a7eb8b418 511 SUPERFAMILY SSF56801 4 509 2.22E-152 T 12-10-2018 AFR_38990 f6362202b85074f278cd1f5a7eb8b418 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_38990 f6362202b85074f278cd1f5a7eb8b418 511 Gene3D G3DSA:3.40.50.12780 2 409 6.6E-118 T 12-10-2018 AFR_42000 d1fdc4953ed6959d88f331080ac1e210 121 SUPERFAMILY SSF54427 5 112 8.15E-9 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_42000 d1fdc4953ed6959d88f331080ac1e210 121 Gene3D G3DSA:3.10.450.50 2 111 1.3E-15 T 12-10-2018 AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 Gene3D G3DSA:1.10.10.10 3 133 5.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 74 1.8E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 1.8E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 128 1.8E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 42 58 1.8E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 SMART SM00347 19 118 8.6E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 SUPERFAMILY SSF46785 33 133 2.48E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23930 f227dd3b475f5e47fa4509cfffd3dca1 168 Pfam PF01047 MarR family 34 83 1.4E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_40235 0a929ec88cf6fe7dd547990b2095f2d9 178 Pfam PF07336 Putative stress-induced transcription regulator 10 102 1.2E-5 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator AFR_40235 0a929ec88cf6fe7dd547990b2095f2d9 178 SUPERFAMILY SSF160904 8 169 8.24E-34 T 12-10-2018 AFR_40235 0a929ec88cf6fe7dd547990b2095f2d9 178 Gene3D G3DSA:1.10.3300.10 1 172 2.4E-44 T 12-10-2018 IPR023286 ABATE domain superfamily AFR_40235 0a929ec88cf6fe7dd547990b2095f2d9 178 Pfam PF11706 CGNR zinc finger 128 170 4.5E-13 T 12-10-2018 IPR021005 Zinc finger, CGNR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 SUPERFAMILY SSF51735 67 308 9.95E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 151 1.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 199 207 1.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 220 239 1.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 Gene3D G3DSA:3.40.50.720 64 312 2.7E-70 T 12-10-2018 AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 77 305 2.2E-55 T 12-10-2018 AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 87 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 151 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 270 290 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 209 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 258 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40010 e4e87ca9b164105513d8dacadf832f13 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 239 1.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04510 9785f8ecc23e245932b56a953bff84b9 216 SUPERFAMILY SSF52166 3 205 1.44E-74 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04510 9785f8ecc23e245932b56a953bff84b9 216 Pfam PF00573 Ribosomal protein L4/L1 family 17 203 1.9E-62 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 AFR_04510 9785f8ecc23e245932b56a953bff84b9 216 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 203 8.8E-69 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04510 9785f8ecc23e245932b56a953bff84b9 216 Gene3D G3DSA:3.40.1370.10 2 207 4.1E-72 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04510 9785f8ecc23e245932b56a953bff84b9 216 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 208 33.092 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 Gene3D G3DSA:3.20.20.450 484 734 2.2E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 Pfam PF00563 EAL domain 487 722 6.5E-71 T 12-10-2018 IPR001633 EAL domain AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 SUPERFAMILY SSF55073 321 471 2.12E-42 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 312 466 3.2E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 SMART SM00267 305 470 3.9E-52 T 12-10-2018 IPR000160 GGDEF domain AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 Gene3D G3DSA:3.30.70.270 310 483 3.2E-50 T 12-10-2018 AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 SUPERFAMILY SSF141868 487 730 1.44E-82 T 12-10-2018 IPR035919 EAL domain superfamily AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 Pfam PF00990 Diguanylate cyclase, GGDEF domain 316 464 1.1E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_25915 3e2a08d19a319f07abd3425a51728d81 737 SMART SM00052 480 727 1.2E-107 T 12-10-2018 IPR001633 EAL domain AFR_16445 b7f4c472b61d269d89ca2ebefa637025 473 SMART SM00458 338 473 1.3E-13 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_16445 b7f4c472b61d269d89ca2ebefa637025 473 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 373 460 2.6E-20 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_16445 b7f4c472b61d269d89ca2ebefa637025 473 SUPERFAMILY SSF50370 341 471 3.71E-36 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_16445 b7f4c472b61d269d89ca2ebefa637025 473 SUPERFAMILY SSF75005 30 336 3.3E-50 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_16445 b7f4c472b61d269d89ca2ebefa637025 473 Pfam PF04616 Glycosyl hydrolases family 43 29 326 3.7E-50 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_16445 b7f4c472b61d269d89ca2ebefa637025 473 Gene3D G3DSA:2.80.10.50 340 472 3.7E-37 T 12-10-2018 AFR_16445 b7f4c472b61d269d89ca2ebefa637025 473 Gene3D G3DSA:2.115.10.20 23 334 1.2E-76 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 Gene3D G3DSA:3.40.50.300 112 362 1.3E-69 T 12-10-2018 AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 SUPERFAMILY SSF52540 117 364 3.22E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 Hamap MF_02040 Iron-sulfur cluster carrier protein. 109 364 33.858 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 ProSitePatterns PS01215 Mrp family signature. 222 238 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 Gene3D G3DSA:3.30.300.130 5 95 5.1E-19 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 119 363 6.2E-89 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 SUPERFAMILY SSF117916 7 93 4.9E-20 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFR_40055 63dfec86ae02b9b27ae9a363556ec517 383 Pfam PF01883 Iron-sulfur cluster assembly protein 9 79 7.2E-18 T 12-10-2018 IPR002744 MIP18 family-like AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 97 155 7.2E-12 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 14 91 1.7E-20 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 Gene3D G3DSA:2.115.10.20 161 467 9.2E-142 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 Pfam PF03664 Glycosyl hydrolase family 62 166 436 2.3E-152 T 12-10-2018 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 SUPERFAMILY SSF75005 186 451 1.27E-29 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 Gene3D G3DSA:2.80.10.50 5 54 8.0E-11 T 12-10-2018 AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 SUPERFAMILY SSF50370 13 150 5.66E-44 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 SMART SM00458 15 150 5.4E-8 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 Gene3D G3DSA:2.80.10.50 55 106 6.0E-17 T 12-10-2018 AFR_14770 30a66d31d3ccc7d9f8819937fc9bee21 467 Gene3D G3DSA:2.80.10.50 107 160 1.5E-11 T 12-10-2018 AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 SUPERFAMILY SSF49299 356 449 7.32E-14 T 12-10-2018 IPR035986 PKD domain superfamily AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 SUPERFAMILY SSF50952 27 305 6.28E-12 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 SUPERFAMILY SSF49785 661 775 6.59E-35 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 Pfam PF00754 F5/8 type C domain 800 917 2.9E-20 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 Pfam PF00754 F5/8 type C domain 654 773 1.3E-23 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 Gene3D G3DSA:2.60.40.10 353 446 2.2E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 Gene3D G3DSA:2.120.10.30 20 352 2.2E-43 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 Pfam PF07995 Glucose / Sorbosone dehydrogenase 128 341 4.1E-13 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 Gene3D G3DSA:2.60.120.260 633 776 1.9E-46 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 Gene3D G3DSA:2.60.120.260 777 921 9.5E-41 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 SUPERFAMILY SSF49785 789 921 3.26E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_16710 02cd9d9c849e80e3e20737f4decb6b38 922 SMART SM00089 360 446 6.4E-7 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_40305 709ef3cc5e54e8df380b30b2f6023f87 414 Pfam PF07690 Major Facilitator Superfamily 225 394 8.7E-14 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_40305 709ef3cc5e54e8df380b30b2f6023f87 414 Pfam PF07690 Major Facilitator Superfamily 32 219 1.6E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_40305 709ef3cc5e54e8df380b30b2f6023f87 414 Gene3D G3DSA:1.20.1250.20 15 389 5.4E-54 T 12-10-2018 AFR_40305 709ef3cc5e54e8df380b30b2f6023f87 414 SUPERFAMILY SSF103473 18 394 2.09E-57 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_35595 49fae2b39e164a4982976661d3999983 496 Pfam PF04055 Radical SAM superfamily 157 328 2.3E-28 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_35595 49fae2b39e164a4982976661d3999983 496 Gene3D G3DSA:3.40.50.12160 11 140 4.8E-33 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AFR_35595 49fae2b39e164a4982976661d3999983 496 SUPERFAMILY SSF102114 138 376 3.27E-58 T 12-10-2018 AFR_35595 49fae2b39e164a4982976661d3999983 496 Gene3D G3DSA:3.80.30.20 150 385 2.3E-88 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFR_35595 49fae2b39e164a4982976661d3999983 496 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 11 446 6.0E-149 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFR_35595 49fae2b39e164a4982976661d3999983 496 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 157 177 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFR_35595 49fae2b39e164a4982976661d3999983 496 SMART SM00729 153 371 2.4E-57 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_35595 49fae2b39e164a4982976661d3999983 496 Pfam PF00919 Uncharacterized protein family UPF0004 13 110 1.6E-27 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFR_35595 49fae2b39e164a4982976661d3999983 496 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 10 451 67.361 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 AFR_35595 49fae2b39e164a4982976661d3999983 496 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 12 447 1.6E-145 T 12-10-2018 AFR_27590 ee9d637055f1ce099f6f136c090ccefd 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 40 133 1.3E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_27590 ee9d637055f1ce099f6f136c090ccefd 144 Gene3D G3DSA:3.10.180.10 4 140 1.3E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_27590 ee9d637055f1ce099f6f136c090ccefd 144 SUPERFAMILY SSF54593 10 141 1.7E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_23105 33b30e24803839bedb249a69173f520b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23105 33b30e24803839bedb249a69173f520b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23105 33b30e24803839bedb249a69173f520b 189 SUPERFAMILY SSF48498 87 168 1.99E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_23105 33b30e24803839bedb249a69173f520b 189 Gene3D G3DSA:1.10.357.10 3 189 3.5E-45 T 12-10-2018 AFR_23105 33b30e24803839bedb249a69173f520b 189 SUPERFAMILY SSF46689 9 90 3.94E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_23105 33b30e24803839bedb249a69173f520b 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 5.1E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12240 ec3618b7c51f9b51c3e769ada6a15e1a 134 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 93 1.8E-18 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_12240 ec3618b7c51f9b51c3e769ada6a15e1a 134 Gene3D G3DSA:2.30.110.10 7 132 8.6E-39 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_12240 ec3618b7c51f9b51c3e769ada6a15e1a 134 SUPERFAMILY SSF50475 8 130 4.82E-28 T 12-10-2018 AFR_12240 ec3618b7c51f9b51c3e769ada6a15e1a 134 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 13 131 1.9E-34 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_42095 134e762e737e8bb0aeb01982bf86244b 244 Gene3D G3DSA:1.10.1040.10 137 243 1.1E-11 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_42095 134e762e737e8bb0aeb01982bf86244b 244 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 132 1.0E-26 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_42095 134e762e737e8bb0aeb01982bf86244b 244 SUPERFAMILY SSF51735 1 133 2.49E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_42095 134e762e737e8bb0aeb01982bf86244b 244 Gene3D G3DSA:3.40.50.720 1 136 2.1E-34 T 12-10-2018 AFR_42095 134e762e737e8bb0aeb01982bf86244b 244 SUPERFAMILY SSF48179 138 234 6.91E-14 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_42095 134e762e737e8bb0aeb01982bf86244b 244 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 140 229 9.1E-9 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SUPERFAMILY SSF56059 680 956 9.19E-96 T 12-10-2018 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SUPERFAMILY SSF52335 961 1098 1.03E-30 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Pfam PF02142 MGS-like domain 979 1067 2.4E-17 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Gene3D G3DSA:3.30.470.20 119 402 5.5E-119 T 12-10-2018 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SUPERFAMILY SSF52440 554 681 4.32E-44 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 544 2.4E-36 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1076 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Gene3D G3DSA:1.10.1030.10 404 550 6.5E-38 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SUPERFAMILY SSF56059 128 400 2.12E-102 T 12-10-2018 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 846 853 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.9E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.9E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.9E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.9E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.9E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.9E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 3.9E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 883 2.1E-36 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.7E-65 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Gene3D G3DSA:3.30.470.20 672 958 1.4E-105 T 12-10-2018 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SUPERFAMILY SSF52440 1 127 5.47E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SMART SM01096 420 544 5.2E-60 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Gene3D G3DSA:3.40.50.1380 959 1100 1.5E-36 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SUPERFAMILY SSF48108 396 550 2.62E-42 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Gene3D G3DSA:3.40.50.20 551 669 2.2E-45 T 12-10-2018 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1088 12.907 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 Gene3D G3DSA:3.40.50.20 1 116 4.9E-47 T 12-10-2018 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 716 730 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_30615 4b89042831211f5e6148d810d40ae4b8 1103 SMART SM00851 978 1067 3.7E-23 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFR_13755 9c3f10533e9b186931d36768bb5e0769 307 SUPERFAMILY SSF50129 4 150 1.83E-34 T 12-10-2018 IPR011032 GroES-like superfamily AFR_13755 9c3f10533e9b186931d36768bb5e0769 307 SMART SM00829 11 304 3.4E-12 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_13755 9c3f10533e9b186931d36768bb5e0769 307 Gene3D G3DSA:3.90.180.10 9 303 1.0E-71 T 12-10-2018 AFR_13755 9c3f10533e9b186931d36768bb5e0769 307 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 1.1E-8 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_13755 9c3f10533e9b186931d36768bb5e0769 307 Pfam PF13602 Zinc-binding dehydrogenase 191 304 3.4E-15 T 12-10-2018 AFR_13755 9c3f10533e9b186931d36768bb5e0769 307 Gene3D G3DSA:3.40.50.720 129 255 1.0E-71 T 12-10-2018 AFR_13755 9c3f10533e9b186931d36768bb5e0769 307 SUPERFAMILY SSF51735 118 303 2.34E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_00885 929835847906409d66796ce2a9598fe8 492 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 8 490 8.6E-155 T 12-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 AFR_00885 929835847906409d66796ce2a9598fe8 492 PRINTS PR00419 Adrenodoxin reductase family signature 7 29 5.1E-5 T 12-10-2018 AFR_00885 929835847906409d66796ce2a9598fe8 492 PRINTS PR00419 Adrenodoxin reductase family signature 30 43 5.1E-5 T 12-10-2018 AFR_00885 929835847906409d66796ce2a9598fe8 492 Gene3D G3DSA:3.50.50.60 5 117 3.6E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_00885 929835847906409d66796ce2a9598fe8 492 Gene3D G3DSA:3.50.50.60 200 325 5.3E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_00885 929835847906409d66796ce2a9598fe8 492 Pfam PF01593 Flavin containing amine oxidoreductase 15 486 3.7E-37 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_00885 929835847906409d66796ce2a9598fe8 492 SUPERFAMILY SSF51905 7 486 4.53E-69 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_35480 a3d5dc477eb03c490edccbf40897d641 184 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 122 1.1E-9 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_35480 a3d5dc477eb03c490edccbf40897d641 184 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 178 1.4E-20 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_35480 a3d5dc477eb03c490edccbf40897d641 184 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 13 178 4.9E-40 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 AFR_35480 a3d5dc477eb03c490edccbf40897d641 184 SUPERFAMILY SSF109854 11 127 1.1E-15 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_35480 a3d5dc477eb03c490edccbf40897d641 184 Gene3D G3DSA:1.20.120.450 54 125 1.5E-5 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_30955 b38e8c952129db075e643b40862d574a 277 TIGRFAM TIGR02069 cyanophycinase: cyanophycinase 10 254 7.5E-71 T 12-10-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 AFR_30955 b38e8c952129db075e643b40862d574a 277 PIRSF PIRSF032067 1 270 1.3E-60 T 12-10-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 AFR_30955 b38e8c952129db075e643b40862d574a 277 Pfam PF03575 Peptidase family S51 10 215 2.8E-22 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 AFR_30955 b38e8c952129db075e643b40862d574a 277 Gene3D G3DSA:3.40.50.880 6 264 1.2E-72 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_30955 b38e8c952129db075e643b40862d574a 277 SUPERFAMILY SSF52317 11 224 4.58E-23 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_33430 087fc5090b49c41397bcebb831dd4010 1036 SUPERFAMILY SSF52540 339 481 4.0E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_23560 701b971da3ef2a236f0386dc11c39108 258 SUPERFAMILY SSF49899 26 257 8.89E-53 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_23560 701b971da3ef2a236f0386dc11c39108 258 PRINTS PR00737 Glycosyl hydrolase family 16 signature 120 136 3.5E-41 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 PRINTS PR00737 Glycosyl hydrolase family 16 signature 141 156 3.5E-41 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 PRINTS PR00737 Glycosyl hydrolase family 16 signature 219 241 3.5E-41 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 PRINTS PR00737 Glycosyl hydrolase family 16 signature 244 256 3.5E-41 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 PRINTS PR00737 Glycosyl hydrolase family 16 signature 101 119 3.5E-41 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 PRINTS PR00737 Glycosyl hydrolase family 16 signature 157 170 3.5E-41 T 12-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 Gene3D G3DSA:2.60.120.200 24 122 1.2E-15 T 12-10-2018 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 Gene3D G3DSA:2.60.120.200 123 258 3.4E-43 T 12-10-2018 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 Pfam PF00722 Glycosyl hydrolases family 16 63 235 4.8E-39 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_23560 701b971da3ef2a236f0386dc11c39108 258 ProSitePatterns PS01034 Glycosyl hydrolases family 16 active sites. 144 154 - T 12-10-2018 IPR008263 Glycoside hydrolase, family 16, active site GO:0004553|GO:0005975 AFR_19280 2221fa5068a08b2a356ef0be81b8aecc 223 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 3 30 1.8E-10 T 12-10-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 AFR_19280 2221fa5068a08b2a356ef0be81b8aecc 223 SUPERFAMILY SSF49482 3 221 1.05E-69 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_19280 2221fa5068a08b2a356ef0be81b8aecc 223 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 4 221 1.2E-103 T 12-10-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 AFR_19280 2221fa5068a08b2a356ef0be81b8aecc 223 Gene3D G3DSA:2.60.130.10 1 222 1.1E-80 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_19280 2221fa5068a08b2a356ef0be81b8aecc 223 Pfam PF00775 Dioxygenase 35 213 7.7E-53 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 AFR_19280 2221fa5068a08b2a356ef0be81b8aecc 223 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 66 94 - T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 AFR_03235 a267b5660d1258a2ada1cad6557e9983 252 SUPERFAMILY SSF54427 130 237 5.85E-17 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_03235 a267b5660d1258a2ada1cad6557e9983 252 SUPERFAMILY SSF54427 1 102 4.1E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_03235 a267b5660d1258a2ada1cad6557e9983 252 Pfam PF12680 SnoaL-like domain 140 234 1.2E-8 T 12-10-2018 IPR037401 SnoaL-like domain AFR_03235 a267b5660d1258a2ada1cad6557e9983 252 Pfam PF12680 SnoaL-like domain 15 100 1.3E-11 T 12-10-2018 IPR037401 SnoaL-like domain AFR_03235 a267b5660d1258a2ada1cad6557e9983 252 Gene3D G3DSA:3.10.450.50 127 252 9.6E-26 T 12-10-2018 AFR_03235 a267b5660d1258a2ada1cad6557e9983 252 Gene3D G3DSA:3.10.450.50 2 116 5.3E-27 T 12-10-2018 AFR_10135 dd863080687336860880cabf40d8f15f 241 Pfam PF00977 Histidine biosynthesis protein 5 230 1.0E-65 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AFR_10135 dd863080687336860880cabf40d8f15f 241 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 237 1.4E-114 T 12-10-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 AFR_10135 dd863080687336860880cabf40d8f15f 241 SUPERFAMILY SSF51366 3 237 1.02E-64 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_10135 dd863080687336860880cabf40d8f15f 241 Gene3D G3DSA:3.20.20.70 1 240 3.5E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10135 dd863080687336860880cabf40d8f15f 241 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 237 32.689 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SUPERFAMILY SSF49464 1365 1445 7.06E-8 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:2.60.40.1120 1364 1444 2.7E-8 T 12-10-2018 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:2.60.40.1120 472 548 1.8E-18 T 12-10-2018 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:2.60.40.1120 820 905 1.8E-11 T 12-10-2018 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SUPERFAMILY SSF52743 147 464 6.81E-57 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Pfam PF13620 Carboxypeptidase regulatory-like domain 471 547 8.6E-16 T 12-10-2018 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 PRINTS PR00723 Subtilisin serine protease family (S8) signature 172 191 8.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 PRINTS PR00723 Subtilisin serine protease family (S8) signature 223 236 8.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 PRINTS PR00723 Subtilisin serine protease family (S8) signature 394 410 8.7E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Pfam PF01344 Kelch motif 1212 1250 2.9E-5 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Pfam PF01344 Kelch motif 1022 1061 9.5E-6 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Pfam PF01344 Kelch motif 1063 1106 6.2E-6 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Pfam PF01344 Kelch motif 1110 1156 2.0E-6 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SUPERFAMILY SSF49899 656 807 5.86E-5 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:2.120.10.80 1000 1136 1.7E-32 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Pfam PF00082 Subtilase family 172 435 2.1E-38 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SUPERFAMILY SSF49464 820 904 3.92E-7 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:2.60.40.1120 555 646 9.9E-8 T 12-10-2018 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SMART SM00612 1219 1265 0.063 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SMART SM00612 1122 1171 0.0045 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SMART SM00612 1028 1074 9.6E-8 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SMART SM00612 1075 1121 1.0E-7 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SMART SM00612 1172 1218 0.92 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SUPERFAMILY SSF49464 471 547 1.29E-15 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:3.40.50.200 155 466 4.4E-62 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SUPERFAMILY SSF117281 1005 1259 2.09E-53 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 SUPERFAMILY SSF49464 554 633 5.62E-9 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:2.120.10.80 1137 1284 4.6E-25 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFR_16965 c0097e8857d06f80f5bcc874dfa66543 1448 Gene3D G3DSA:2.60.120.200 649 809 1.3E-7 T 12-10-2018 AFR_29730 b6cc449f034e4717f20792954640955a 407 Pfam PF09594 Glycosyltransferase family 87 80 308 2.3E-43 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 Pfam PF00216 Bacterial DNA-binding protein 1 88 2.4E-24 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 SMART SM00411 1 89 5.5E-33 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 2.8E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 2.8E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 2.8E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 Gene3D G3DSA:4.10.520.10 1 99 7.1E-29 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFR_36685 f92facf986de7163e9769b1ebc3cc738 296 SUPERFAMILY SSF47729 1 92 1.35E-23 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 24 126 4.4E-14 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 SUPERFAMILY SSF51735 136 327 4.45E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 Gene3D G3DSA:3.40.50.10860 7 336 1.6E-95 T 12-10-2018 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 SMART SM00839 137 336 5.2E-15 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 SUPERFAMILY SSF53223 6 139 5.12E-29 T 12-10-2018 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 280 291 3.5E-13 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 171 191 3.5E-13 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 61 75 3.5E-13 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 127 149 3.5E-13 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 PIRSF PIRSF000188 1 341 5.3E-93 T 12-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 AFR_16115 30b16b92a43cae76a02e8f72ec3ed06b 343 Gene3D G3DSA:3.40.50.720 129 331 1.6E-95 T 12-10-2018 AFR_35150 4932c501f0723fda2cbf8e7286e044c9 201 Gene3D G3DSA:3.40.50.360 2 201 2.2E-57 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_35150 4932c501f0723fda2cbf8e7286e044c9 201 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 173 2.9E-39 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AFR_35150 4932c501f0723fda2cbf8e7286e044c9 201 Pfam PF03358 NADPH-dependent FMN reductase 15 131 5.9E-16 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_35150 4932c501f0723fda2cbf8e7286e044c9 201 SUPERFAMILY SSF52218 5 195 1.31E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_22220 2eb5f944ede15a3bb2feba66ec033000 210 Gene3D G3DSA:1.10.510.10 90 190 1.7E-9 T 12-10-2018 AFR_22220 2eb5f944ede15a3bb2feba66ec033000 210 SUPERFAMILY SSF56112 3 175 1.12E-15 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_22220 2eb5f944ede15a3bb2feba66ec033000 210 Gene3D G3DSA:3.30.200.20 1 87 5.7E-11 T 12-10-2018 AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 Gene3D G3DSA:1.20.120.530 76 207 2.1E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 60 2.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 Gene3D G3DSA:1.10.10.10 1 64 4.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 SMART SM00895 81 204 4.1E-17 T 12-10-2018 IPR011711 GntR, C-terminal AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 Pfam PF07729 FCD domain 82 201 1.5E-19 T 12-10-2018 IPR011711 GntR, C-terminal AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 20 34 8.4E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 50 8.4E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 SUPERFAMILY SSF48008 78 204 3.92E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 SUPERFAMILY SSF46785 1 64 3.59E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_02150 b925f220a101fb2f8a5155dce8c63d4c 209 SMART SM00345 1 60 2.0E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_41615 aa9e3ce59e1d758b326f00cab64d5046 483 Pfam PF01039 Carboxyl transferase domain 48 432 8.3E-63 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFR_41615 aa9e3ce59e1d758b326f00cab64d5046 483 Gene3D G3DSA:3.90.226.10 5 482 4.1E-184 T 12-10-2018 AFR_41615 aa9e3ce59e1d758b326f00cab64d5046 483 SUPERFAMILY SSF52096 22 261 4.98E-47 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_41615 aa9e3ce59e1d758b326f00cab64d5046 483 SUPERFAMILY SSF52096 233 464 4.26E-36 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_41615 aa9e3ce59e1d758b326f00cab64d5046 483 Gene3D G3DSA:3.90.226.10 37 265 4.1E-184 T 12-10-2018 AFR_03460 eaa7d67ce7779cd80d255225c0e49471 338 SUPERFAMILY SSF50939 277 336 8.34E-7 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 AFR_03460 eaa7d67ce7779cd80d255225c0e49471 338 SUPERFAMILY SSF50939 160 314 1.14E-5 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 AFR_03460 eaa7d67ce7779cd80d255225c0e49471 338 SUPERFAMILY SSF50939 24 121 2.55E-6 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 AFR_26105 99e8188b94a2bf41b1657bb6b0c3b3b3 250 SUPERFAMILY SSF51658 42 247 1.11E-22 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_26105 99e8188b94a2bf41b1657bb6b0c3b3b3 250 Pfam PF01261 Xylose isomerase-like TIM barrel 22 185 2.6E-8 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_26105 99e8188b94a2bf41b1657bb6b0c3b3b3 250 Gene3D G3DSA:3.20.20.150 1 246 1.8E-29 T 12-10-2018 AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 SUPERFAMILY SSF51735 1 224 3.51E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 Gene3D G3DSA:3.40.50.720 1 290 1.1E-65 T 12-10-2018 AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.3E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 7.3E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 7.3E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.3E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.3E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15450 d4bfaf64817860d9be50127216acf7ea 290 Pfam PF00106 short chain dehydrogenase 4 193 4.4E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36030 df9d23a6199192f2ff3b50ecc6c7d963 189 SUPERFAMILY SSF109604 35 137 3.49E-9 T 12-10-2018 AFR_36030 df9d23a6199192f2ff3b50ecc6c7d963 189 Pfam PF01966 HD domain 37 136 1.5E-6 T 12-10-2018 IPR006674 HD domain AFR_08230 a65367dcedf98b9c8b379424f9926d6f 335 Pfam PF01261 Xylose isomerase-like TIM barrel 22 251 4.3E-40 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_08230 a65367dcedf98b9c8b379424f9926d6f 335 Gene3D G3DSA:3.20.20.150 2 324 2.7E-100 T 12-10-2018 AFR_08230 a65367dcedf98b9c8b379424f9926d6f 335 Pfam PF07582 AP endonuclease family 2 C terminus 276 330 1.1E-23 T 12-10-2018 IPR011418 AP endonuclease, family 2, C-terminal AFR_08230 a65367dcedf98b9c8b379424f9926d6f 335 SUPERFAMILY SSF51658 7 319 1.07E-58 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_05245 c141c04223e93c74971fd994b67dc2f5 120 SUPERFAMILY SSF46955 1 111 3.55E-25 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_05245 c141c04223e93c74971fd994b67dc2f5 120 SMART SM00422 1 69 9.6E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05245 c141c04223e93c74971fd994b67dc2f5 120 Gene3D G3DSA:1.10.1660.10 1 119 1.9E-28 T 12-10-2018 AFR_05245 c141c04223e93c74971fd994b67dc2f5 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05245 c141c04223e93c74971fd994b67dc2f5 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05245 c141c04223e93c74971fd994b67dc2f5 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_05245 c141c04223e93c74971fd994b67dc2f5 120 Pfam PF13411 MerR HTH family regulatory protein 1 66 7.5E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_16830 b7933d20eb76aed61960487c71eb665b 348 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 122 1.0E-25 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_16830 b7933d20eb76aed61960487c71eb665b 348 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 249 1.4E-11 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_16830 b7933d20eb76aed61960487c71eb665b 348 SUPERFAMILY SSF51735 5 158 1.21E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16830 b7933d20eb76aed61960487c71eb665b 348 SUPERFAMILY SSF55347 129 261 8.01E-36 T 12-10-2018 AFR_20435 24ceb887e69bb891acde62f216256664 272 Gene3D G3DSA:3.40.190.10 117 221 1.9E-99 T 12-10-2018 AFR_20435 24ceb887e69bb891acde62f216256664 272 SUPERFAMILY SSF53850 34 272 1.71E-78 T 12-10-2018 AFR_20435 24ceb887e69bb891acde62f216256664 272 PIRSF PIRSF002854 1 272 9.2E-107 T 12-10-2018 IPR004872 Lipoprotein NlpA family AFR_20435 24ceb887e69bb891acde62f216256664 272 Gene3D G3DSA:3.40.190.10 34 268 1.9E-99 T 12-10-2018 AFR_20435 24ceb887e69bb891acde62f216256664 272 Pfam PF03180 NLPA lipoprotein 35 271 1.5E-90 T 12-10-2018 IPR004872 Lipoprotein NlpA family AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 SUPERFAMILY SSF53850 98 284 5.61E-21 T 12-10-2018 AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 Gene3D G3DSA:3.40.190.10 122 266 6.1E-10 T 12-10-2018 AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 Gene3D G3DSA:1.10.10.10 9 89 9.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 SUPERFAMILY SSF46785 9 86 3.75E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 Gene3D G3DSA:3.40.190.10 167 259 6.1E-10 T 12-10-2018 AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 4.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 4.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 4.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 1.9E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_20235 cfdc9b8d8c3ef4fff3548867c3812d14 288 Pfam PF03466 LysR substrate binding domain 103 282 1.0E-16 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 Pfam PF00437 Type II/IV secretion system protein 179 444 1.0E-78 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 SUPERFAMILY SSF160246 5 140 1.7E-27 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 SMART SM00382 305 428 2.6E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 SUPERFAMILY SSF52540 153 552 1.1E-98 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 Gene3D G3DSA:3.30.450.90 142 277 1.5E-46 T 12-10-2018 AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 Gene3D G3DSA:3.30.300.160 63 141 4.3E-10 T 12-10-2018 AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 Gene3D G3DSA:3.40.50.300 280 554 9.1E-106 T 12-10-2018 AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 372 386 - T 12-10-2018 IPR001482 Type II/IV secretion system protein AFR_05995 0a54cc9d84d7ca00bdc5333ae783721c 554 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 40 144 3.6E-20 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 SUPERFAMILY SSF53822 69 329 5.72E-60 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 Gene3D G3DSA:1.10.260.40 1 57 2.3E-22 T 12-10-2018 AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 SUPERFAMILY SSF47413 1 56 7.29E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 Pfam PF13377 Periplasmic binding protein-like domain 166 326 3.7E-38 T 12-10-2018 AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 Gene3D G3DSA:3.40.50.2300 157 321 5.3E-74 T 12-10-2018 AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 3.1E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 12-10-2018 AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 Gene3D G3DSA:3.40.50.2300 74 317 5.3E-74 T 12-10-2018 AFR_18935 66f2b74ecc7b01445e1c56272d0ce47f 330 SMART SM00354 1 68 4.0E-25 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_01125 434f696de02498fb86ed8d05ac9cffae 402 Pfam PF12704 MacB-like periplasmic core domain 33 244 2.1E-16 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_01125 434f696de02498fb86ed8d05ac9cffae 402 Pfam PF02687 FtsX-like permease family 307 395 1.7E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_40565 914f1606d82958f5397579569ca28b59 159 Gene3D G3DSA:3.40.1550.10 13 149 5.4E-15 T 12-10-2018 IPR028976 CheC-like superfamily AFR_40565 914f1606d82958f5397579569ca28b59 159 Pfam PF13690 Chemotaxis phosphatase CheX 46 123 3.8E-14 T 12-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain AFR_40565 914f1606d82958f5397579569ca28b59 159 SUPERFAMILY SSF103039 42 145 7.46E-14 T 12-10-2018 IPR028976 CheC-like superfamily AFR_15940 7dc01098f2781b66c833d449baa92c02 408 Gene3D G3DSA:2.40.37.10 33 407 3.8E-96 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 SUPERFAMILY SSF51419 34 293 8.83E-60 T 12-10-2018 IPR029066 PLP-binding barrel AFR_15940 7dc01098f2781b66c833d449baa92c02 408 SUPERFAMILY SSF50621 271 408 5.86E-36 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01182 Ornithine decarboxylase signature 353 363 4.7E-8 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01182 Ornithine decarboxylase signature 373 386 4.7E-8 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01182 Ornithine decarboxylase signature 105 129 4.7E-8 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01182 Ornithine decarboxylase signature 61 88 4.7E-8 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 Gene3D G3DSA:3.20.20.10 41 293 3.8E-96 T 12-10-2018 IPR029066 PLP-binding barrel AFR_15940 7dc01098f2781b66c833d449baa92c02 408 TIGRFAM TIGR03099 dCO2ase_PEP1: pyridoxal-dependent decarboxylase, exosortase A system-associated 11 408 6.2E-174 T 12-10-2018 IPR017530 Pyridoxal-dependent decarboxylase, exosortase system type 1 associated AFR_15940 7dc01098f2781b66c833d449baa92c02 408 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 52 291 1.7E-34 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 1.4E-9 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 281 300 1.4E-9 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 1.4E-9 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 193 206 1.4E-9 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_15940 7dc01098f2781b66c833d449baa92c02 408 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 292 386 6.3E-17 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFR_33615 39dc26df789bb49010a2b8cf93b12bc8 183 SMART SM00418 8 107 9.6E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33615 39dc26df789bb49010a2b8cf93b12bc8 183 Pfam PF12840 Helix-turn-helix domain 8 64 3.9E-15 T 12-10-2018 AFR_33615 39dc26df789bb49010a2b8cf93b12bc8 183 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 3.0E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33615 39dc26df789bb49010a2b8cf93b12bc8 183 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 3.0E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33615 39dc26df789bb49010a2b8cf93b12bc8 183 SUPERFAMILY SSF46785 2 89 1.17E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_33615 39dc26df789bb49010a2b8cf93b12bc8 183 Gene3D G3DSA:1.10.10.10 5 104 2.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27265 4f557078c27c564450c85f82c0f4d8af 195 Pfam PF11937 Protein of unknown function (DUF3455) 59 193 5.8E-21 T 12-10-2018 IPR021851 Protein of unknown function DUF3455 AFR_03520 b67f52fabdf9170f046ab70ad4cf25f6 438 Gene3D G3DSA:1.10.10.10 332 438 9.3E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03520 b67f52fabdf9170f046ab70ad4cf25f6 438 SUPERFAMILY SSF46894 373 436 7.48E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_03520 b67f52fabdf9170f046ab70ad4cf25f6 438 SMART SM00421 377 434 1.3E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03520 b67f52fabdf9170f046ab70ad4cf25f6 438 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 394 410 9.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03520 b67f52fabdf9170f046ab70ad4cf25f6 438 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 380 394 9.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03520 b67f52fabdf9170f046ab70ad4cf25f6 438 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 410 422 9.7E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03520 b67f52fabdf9170f046ab70ad4cf25f6 438 Pfam PF00196 Bacterial regulatory proteins, luxR family 380 432 2.6E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Pfam PF00873 AcrB/AcrD/AcrF family 6 1010 3.2E-220 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 SUPERFAMILY SSF82693 42 129 1.1E-23 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 SUPERFAMILY SSF82693 134 308 3.24E-12 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:1.20.1640.10 503 1008 2.5E-278 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:3.30.2090.10 706 793 2.5E-278 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 SUPERFAMILY SSF82714 707 790 2.62E-11 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:3.30.2090.10 178 267 2.5E-278 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:3.30.70.1430 41 801 2.5E-278 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 PRINTS PR00702 Acriflavin resistance protein family signature 381 405 4.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 PRINTS PR00702 Acriflavin resistance protein family signature 434 457 4.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 PRINTS PR00702 Acriflavin resistance protein family signature 326 349 4.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 4.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 PRINTS PR00702 Acriflavin resistance protein family signature 353 374 4.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 PRINTS PR00702 Acriflavin resistance protein family signature 459 482 4.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:3.30.70.1430 560 657 2.5E-278 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:3.30.70.1440 658 850 2.5E-278 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:1.20.1640.10 14 502 2.5E-278 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 Gene3D G3DSA:3.30.70.1320 132 322 2.5E-278 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 SUPERFAMILY SSF82866 790 1014 2.35E-49 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 SUPERFAMILY SSF82714 183 262 3.92E-10 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 SUPERFAMILY SSF82866 290 486 5.49E-43 T 12-10-2018 AFR_37470 41fbb69749ab0485cc6aa8f78f150bf6 1111 SUPERFAMILY SSF82693 560 648 3.71E-7 T 12-10-2018 AFR_38975 c51d7b8bc934cdb91895fca7dbdc22e1 466 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_38975 c51d7b8bc934cdb91895fca7dbdc22e1 466 SUPERFAMILY SSF53720 6 464 7.72E-154 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_38975 c51d7b8bc934cdb91895fca7dbdc22e1 466 Pfam PF00171 Aldehyde dehydrogenase family 14 464 1.3E-161 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_38975 c51d7b8bc934cdb91895fca7dbdc22e1 466 Gene3D G3DSA:3.40.605.10 10 462 4.0E-167 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_38975 c51d7b8bc934cdb91895fca7dbdc22e1 466 Gene3D G3DSA:3.40.309.10 250 434 4.0E-167 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_38975 c51d7b8bc934cdb91895fca7dbdc22e1 466 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 Gene3D G3DSA:2.60.40.1180 52 499 3.8E-152 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 Pfam PF00754 F5/8 type C domain 516 629 2.3E-18 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 SUPERFAMILY SSF51445 74 433 1.53E-73 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 PRINTS PR00843 Glycosyl hydrolase family 30 signature 100 126 2.9E-11 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 PRINTS PR00843 Glycosyl hydrolase family 30 signature 64 84 2.9E-11 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 PRINTS PR00843 Glycosyl hydrolase family 30 signature 200 217 2.9E-11 T 12-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 Gene3D G3DSA:3.20.20.80 72 433 3.8E-152 T 12-10-2018 AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 SUPERFAMILY SSF49785 513 634 3.01E-25 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 SUPERFAMILY SSF51011 428 499 7.91E-6 T 12-10-2018 AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 Gene3D G3DSA:2.60.120.260 510 635 7.4E-26 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 75 429 8.8E-41 T 12-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_24505 49a6863794fed4e632f9ac8d45ad7611 635 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 432 497 3.3E-14 T 12-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 AFR_07940 7080e136035e2d00772cbb9aae56d238 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_07940 7080e136035e2d00772cbb9aae56d238 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 247 1.4E-55 T 12-10-2018 AFR_07940 7080e136035e2d00772cbb9aae56d238 253 Gene3D G3DSA:3.40.50.720 1 250 6.0E-76 T 12-10-2018 AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 SUPERFAMILY SSF51735 3 248 5.3E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.8E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.8E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.8E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.8E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.8E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07940 7080e136035e2d00772cbb9aae56d238 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.8E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40515 ed215d5715ce1277ff4600300beef445 283 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 87 282 1.6E-74 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 259 271 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 Pfam PF00813 FliP family 87 278 2.0E-73 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 211 231 4.3E-59 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 103 123 4.3E-59 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 256 281 4.3E-59 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 232 253 4.3E-59 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 123 142 4.3E-59 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_40515 ed215d5715ce1277ff4600300beef445 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 84 103 4.3E-59 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 TIGRFAM TIGR00277 HDIG: HDIG domain 386 463 7.2E-21 T 12-10-2018 IPR006675 HDIG domain AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 SUPERFAMILY SSF54791 262 353 3.56E-13 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 Gene3D G3DSA:1.10.3210.10 379 533 4.7E-13 T 12-10-2018 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 SUPERFAMILY SSF109604 379 502 9.87E-26 T 12-10-2018 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 Pfam PF01966 HD domain 391 481 4.3E-16 T 12-10-2018 IPR006674 HD domain AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 Hamap MF_00335 Ribonuclease Y [rny]. 6 574 23.955 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 74 574 1.5E-186 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 Pfam PF12072 Domain of unknown function (DUF3552) 80 258 4.7E-24 T 12-10-2018 IPR022711 Ribonuclease Y, N-terminal AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 SMART SM00471 386 492 1.2E-8 T 12-10-2018 IPR003607 HD/PDEase domain AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 Pfam PF00013 KH domain 268 305 4.1E-6 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 SMART SM00322 262 357 4.9E-4 T 12-10-2018 IPR004087 K Homology domain GO:0003676 AFR_35635 c02bdffb3376f0cf463d970ad6908494 574 Gene3D G3DSA:3.30.1370.10 270 362 5.7E-6 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFR_09795 59efaba464dd37304769be96772a633c 642 SUPERFAMILY SSF51905 40 459 9.94E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09795 59efaba464dd37304769be96772a633c 642 Pfam PF00890 FAD binding domain 44 449 1.2E-56 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09795 59efaba464dd37304769be96772a633c 642 SUPERFAMILY SSF46977 501 641 3.14E-37 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09795 59efaba464dd37304769be96772a633c 642 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 63 6.3E-6 T 12-10-2018 AFR_09795 59efaba464dd37304769be96772a633c 642 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 413 435 6.3E-6 T 12-10-2018 AFR_09795 59efaba464dd37304769be96772a633c 642 SUPERFAMILY SSF56425 269 411 4.88E-33 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09795 59efaba464dd37304769be96772a633c 642 Gene3D G3DSA:1.20.58.100 481 598 2.6E-21 T 12-10-2018 AFR_09795 59efaba464dd37304769be96772a633c 642 Pfam PF02910 Fumarate reductase flavoprotein C-term 510 641 2.2E-33 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09795 59efaba464dd37304769be96772a633c 642 Gene3D G3DSA:3.50.50.60 44 458 9.3E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09795 59efaba464dd37304769be96772a633c 642 Gene3D G3DSA:3.90.700.10 300 424 9.3E-100 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09795 59efaba464dd37304769be96772a633c 642 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 44 641 4.5E-298 T 12-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 Gene3D G3DSA:1.10.10.10 77 160 1.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 SUPERFAMILY SSF88946 3 74 5.1E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 Gene3D G3DSA:1.10.1740.10 1 75 2.3E-10 T 12-10-2018 AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 157 6.6E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 Pfam PF08281 Sigma-70, region 4 101 153 7.4E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 159 5.8E-46 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 Pfam PF04542 Sigma-70 region 2 11 74 2.4E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24080 e1da83a91ad62591702c64c34f3720ad 165 SUPERFAMILY SSF88659 85 157 1.42E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 Gene3D G3DSA:3.30.70.2530 178 263 1.6E-88 T 12-10-2018 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 SUPERFAMILY SSF56176 5 175 1.58E-29 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 Pfam PF01565 FAD binding domain 35 146 7.1E-19 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 Gene3D G3DSA:3.30.70.2520 282 375 3.3E-34 T 12-10-2018 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 Pfam PF04030 D-arabinono-1,4-lactone oxidase 284 409 2.2E-22 T 12-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 Gene3D G3DSA:3.30.465.10 71 280 1.6E-88 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 Gene3D G3DSA:3.30.43.10 2 65 3.9E-17 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 PIRSF PIRSF000136 278 413 2.1E-9 T 12-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 PIRSF PIRSF000136 2 204 1.8E-39 T 12-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 AFR_25135 01750bb3c7dad6430ebadaa38226ff84 413 Gene3D G3DSA:1.10.45.10 377 413 1.3E-10 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFR_31880 7f6188a06ddc34767275c58571057ee4 507 SUPERFAMILY SSF52540 76 358 4.42E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31880 7f6188a06ddc34767275c58571057ee4 507 Pfam PF00270 DEAD/DEAH box helicase 26 191 6.8E-42 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_31880 7f6188a06ddc34767275c58571057ee4 507 SMART SM00490 257 338 9.7E-24 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_31880 7f6188a06ddc34767275c58571057ee4 507 Gene3D G3DSA:3.40.50.300 222 380 3.8E-40 T 12-10-2018 AFR_31880 7f6188a06ddc34767275c58571057ee4 507 SMART SM00487 21 223 4.8E-47 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_31880 7f6188a06ddc34767275c58571057ee4 507 Gene3D G3DSA:3.40.50.300 1 211 4.1E-65 T 12-10-2018 AFR_31880 7f6188a06ddc34767275c58571057ee4 507 Pfam PF00271 Helicase conserved C-terminal domain 237 338 1.4E-22 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_02790 1f89176f080c51b88686b391cd1afced 775 Pfam PF00990 Diguanylate cyclase, GGDEF domain 336 484 3.5E-45 T 12-10-2018 IPR000160 GGDEF domain AFR_02790 1f89176f080c51b88686b391cd1afced 775 SMART SM00267 325 493 2.9E-57 T 12-10-2018 IPR000160 GGDEF domain AFR_02790 1f89176f080c51b88686b391cd1afced 775 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 332 484 2.3E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_02790 1f89176f080c51b88686b391cd1afced 775 Pfam PF00563 EAL domain 510 743 7.0E-67 T 12-10-2018 IPR001633 EAL domain AFR_02790 1f89176f080c51b88686b391cd1afced 775 SMART SM00052 503 748 2.8E-97 T 12-10-2018 IPR001633 EAL domain AFR_02790 1f89176f080c51b88686b391cd1afced 775 Gene3D G3DSA:3.20.20.450 507 764 4.2E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02790 1f89176f080c51b88686b391cd1afced 775 Gene3D G3DSA:3.30.70.270 330 506 4.1E-56 T 12-10-2018 AFR_02790 1f89176f080c51b88686b391cd1afced 775 SUPERFAMILY SSF55073 341 494 3.92E-47 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_02790 1f89176f080c51b88686b391cd1afced 775 SUPERFAMILY SSF141868 510 755 2.48E-79 T 12-10-2018 IPR035919 EAL domain superfamily AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 Gene3D G3DSA:4.10.1250.10 239 278 1.3E-11 T 12-10-2018 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 PIRSF PIRSF006487 1 366 8.7E-86 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 358 4.4E-22 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 13 259 4.7E-82 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 Gene3D G3DSA:2.40.30.110 282 366 9.9E-25 T 12-10-2018 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 7 363 40.684 T 12-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 Gene3D G3DSA:3.30.1360.120 11 235 1.3E-75 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 11 363 8.6E-96 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 SUPERFAMILY SSF101790 273 363 1.03E-24 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 SUPERFAMILY SSF103025 10 280 3.3E-89 T 12-10-2018 AFR_09275 e0f0d492881a3ca3fd60ec9cf338f2d4 366 Gene3D G3DSA:3.30.70.1400 59 144 1.3E-75 T 12-10-2018 AFR_00380 707f125d39b68652ba04cca6e7b85a7d 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 17 100 2.1E-6 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_00380 707f125d39b68652ba04cca6e7b85a7d 170 SUPERFAMILY SSF50475 16 128 2.55E-15 T 12-10-2018 AFR_00380 707f125d39b68652ba04cca6e7b85a7d 170 Gene3D G3DSA:2.30.110.10 7 132 2.4E-14 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_36980 88e6d1a466dcf5cc37f9ac6506e37a7a 99 SUPERFAMILY SSF141000 4 94 7.19E-26 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 AFR_36980 88e6d1a466dcf5cc37f9ac6506e37a7a 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 5.2E-14 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFR_36980 88e6d1a466dcf5cc37f9ac6506e37a7a 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 22.241 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFR_36980 88e6d1a466dcf5cc37f9ac6506e37a7a 99 Gene3D G3DSA:1.10.20.60 1 94 5.4E-22 T 12-10-2018 AFR_36980 88e6d1a466dcf5cc37f9ac6506e37a7a 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 8.7E-23 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFR_13170 2f523249538d972941dd60522d3fc68b 250 Gene3D G3DSA:3.40.50.720 3 240 2.2E-48 T 12-10-2018 AFR_13170 2f523249538d972941dd60522d3fc68b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13170 2f523249538d972941dd60522d3fc68b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13170 2f523249538d972941dd60522d3fc68b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13170 2f523249538d972941dd60522d3fc68b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13170 2f523249538d972941dd60522d3fc68b 250 SUPERFAMILY SSF51735 2 207 4.57E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13170 2f523249538d972941dd60522d3fc68b 250 Pfam PF00106 short chain dehydrogenase 7 195 5.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13170 2f523249538d972941dd60522d3fc68b 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 SUPERFAMILY SSF46894 262 335 2.18E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 Pfam PF00196 Bacterial regulatory proteins, luxR family 274 329 3.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 SMART SM00421 272 329 1.3E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 SMART SM00065 21 165 1.3E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 Gene3D G3DSA:3.30.450.40 8 158 4.7E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 289 305 3.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 275 289 3.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 305 317 3.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 SUPERFAMILY SSF55781 9 155 1.02E-17 T 12-10-2018 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 Pfam PF13185 GAF domain 22 155 5.7E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_23215 fc4da2d26d34b4950e4eb7fbfd32c1d4 348 Gene3D G3DSA:1.10.10.10 270 335 1.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06040 3657e36a0c2efd97094dc215bb4380bf 140 Pfam PF00072 Response regulator receiver domain 4 114 4.9E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_06040 3657e36a0c2efd97094dc215bb4380bf 140 SUPERFAMILY SSF52172 3 120 6.12E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_06040 3657e36a0c2efd97094dc215bb4380bf 140 SMART SM00448 2 114 1.5E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_06040 3657e36a0c2efd97094dc215bb4380bf 140 Gene3D G3DSA:3.40.50.12740 2 136 4.1E-29 T 12-10-2018 AFR_26515 6b4012f11312193287888e7062299135 237 SUPERFAMILY SSF53335 8 223 1.44E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_26515 6b4012f11312193287888e7062299135 237 Gene3D G3DSA:3.40.50.150 53 237 5.5E-22 T 12-10-2018 AFR_24570 fb980ea2d3e19b67de9f81602de60de5 309 Gene3D G3DSA:3.30.9.10 80 266 2.7E-88 T 12-10-2018 AFR_24570 fb980ea2d3e19b67de9f81602de60de5 309 ProSitePatterns PS00677 D-amino acid oxidases signature. 283 301 - T 12-10-2018 IPR006181 D-amino acid oxidase, conserved site GO:0003884|GO:0055114 Reactome: R-HSA-389661|Reactome: R-HSA-9033241 AFR_24570 fb980ea2d3e19b67de9f81602de60de5 309 PIRSF PIRSF000189 1 309 3.8E-80 T 12-10-2018 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 Reactome: R-HSA-389661|Reactome: R-HSA-9033241 AFR_24570 fb980ea2d3e19b67de9f81602de60de5 309 Pfam PF01266 FAD dependent oxidoreductase 3 307 1.5E-37 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_24570 fb980ea2d3e19b67de9f81602de60de5 309 Gene3D G3DSA:3.40.50.720 4 307 2.7E-88 T 12-10-2018 AFR_24570 fb980ea2d3e19b67de9f81602de60de5 309 SUPERFAMILY SSF54373 181 267 2.35E-20 T 12-10-2018 AFR_24570 fb980ea2d3e19b67de9f81602de60de5 309 SUPERFAMILY SSF51971 1 308 8.0E-32 T 12-10-2018 AFR_21615 61de1181f201eb9f673aecbe2b3ca77b 119 Gene3D G3DSA:3.10.450.50 2 116 1.2E-22 T 12-10-2018 AFR_21615 61de1181f201eb9f673aecbe2b3ca77b 119 SUPERFAMILY SSF54427 3 115 2.92E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_21615 61de1181f201eb9f673aecbe2b3ca77b 119 Pfam PF14534 Domain of unknown function (DUF4440) 5 109 3.3E-12 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 AFR_42435 3c550cc0588140047ec4a2e91a594705 247 SMART SM00448 3 114 7.8E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_42435 3c550cc0588140047ec4a2e91a594705 247 Pfam PF00072 Response regulator receiver domain 5 114 1.6E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_42435 3c550cc0588140047ec4a2e91a594705 247 SMART SM00850 143 238 4.8E-27 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 AFR_42435 3c550cc0588140047ec4a2e91a594705 247 SUPERFAMILY SSF52172 4 132 7.68E-31 T 12-10-2018 IPR011006 CheY-like superfamily AFR_42435 3c550cc0588140047ec4a2e91a594705 247 Gene3D G3DSA:3.40.50.2300 2 122 1.0E-30 T 12-10-2018 AFR_42435 3c550cc0588140047ec4a2e91a594705 247 Pfam PF04397 LytTr DNA-binding domain 145 237 1.5E-21 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 AFR_42435 3c550cc0588140047ec4a2e91a594705 247 Gene3D G3DSA:2.40.50.1020 141 245 7.0E-9 T 12-10-2018 AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 Gene3D G3DSA:3.40.50.300 349 544 9.9E-35 T 12-10-2018 AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 SMART SM00382 374 541 1.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 SMART SM00382 29 232 5.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 SUPERFAMILY SSF52540 364 542 5.58E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 SUPERFAMILY SSF52540 6 229 8.68E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 Gene3D G3DSA:3.40.50.300 10 323 1.3E-50 T 12-10-2018 AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 Pfam PF00005 ABC transporter 367 495 2.9E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_21040 9e64ba54ea0f4649e9908c4f1f62d405 544 Pfam PF00005 ABC transporter 22 187 1.1E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_17680 15b38770c0fd9cfe467b782dd3c6b607 318 Pfam PF13280 WYL domain 137 307 2.8E-32 T 12-10-2018 IPR026881 WYL domain AFR_17680 15b38770c0fd9cfe467b782dd3c6b607 318 Gene3D G3DSA:1.10.10.10 1 63 2.6E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17680 15b38770c0fd9cfe467b782dd3c6b607 318 PIRSF PIRSF016838 68 315 1.2E-17 T 12-10-2018 IPR028349 Protein PafC AFR_17680 15b38770c0fd9cfe467b782dd3c6b607 318 PIRSF PIRSF016838 1 54 0.007 T 12-10-2018 IPR028349 Protein PafC AFR_17680 15b38770c0fd9cfe467b782dd3c6b607 318 SUPERFAMILY SSF46785 2 59 3.64E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17680 15b38770c0fd9cfe467b782dd3c6b607 318 Pfam PF08279 HTH domain 11 56 6.9E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 Gene3D G3DSA:3.30.450.20 172 295 1.9E-13 T 12-10-2018 AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 Pfam PF08447 PAS fold 207 284 5.4E-7 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 Gene3D G3DSA:3.30.70.270 303 487 7.0E-55 T 12-10-2018 AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 Gene3D G3DSA:3.20.20.450 488 745 1.6E-102 T 12-10-2018 IPR035919 EAL domain superfamily AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 305 472 2.6E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 SMART SM00267 298 473 6.3E-58 T 12-10-2018 IPR000160 GGDEF domain AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 SUPERFAMILY SSF55785 179 296 8.05E-13 T 12-10-2018 IPR035965 PAS domain superfamily AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 Pfam PF00990 Diguanylate cyclase, GGDEF domain 310 469 2.5E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 SMART SM00052 483 731 5.2E-120 T 12-10-2018 IPR001633 EAL domain AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 SUPERFAMILY SSF55073 314 475 9.42E-46 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 SUPERFAMILY SSF141868 491 738 2.88E-91 T 12-10-2018 IPR035919 EAL domain superfamily AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 Pfam PF00563 EAL domain 490 726 1.0E-74 T 12-10-2018 IPR001633 EAL domain AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 SMART SM00091 184 249 4.9E-4 T 12-10-2018 IPR000014 PAS domain AFR_28035 a7d32d9a62e7707e6acaea328664616d 750 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 183 305 1.2E-8 T 12-10-2018 IPR000014 PAS domain AFR_27790 705c593d9b701233f1893a4d0fd6e8ec 401 Gene3D G3DSA:3.40.50.720 4 396 1.2E-140 T 12-10-2018 AFR_27790 705c593d9b701233f1893a4d0fd6e8ec 401 SUPERFAMILY SSF51735 1 165 1.82E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_27790 705c593d9b701233f1893a4d0fd6e8ec 401 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 139 1.1E-13 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AFR_27790 705c593d9b701233f1893a4d0fd6e8ec 401 Gene3D G3DSA:3.30.360.10 154 353 1.2E-140 T 12-10-2018 AFR_27790 705c593d9b701233f1893a4d0fd6e8ec 401 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 144 393 4.7E-20 T 12-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 AFR_09800 84eb7846a6c4aa8ce1897b4ca0eec1d4 210 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 78 195 1.3E-6 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09800 84eb7846a6c4aa8ce1897b4ca0eec1d4 210 SUPERFAMILY SSF81343 1 209 2.78E-43 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_09800 84eb7846a6c4aa8ce1897b4ca0eec1d4 210 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 1 209 9.8E-55 T 12-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit AFR_09800 84eb7846a6c4aa8ce1897b4ca0eec1d4 210 Gene3D G3DSA:1.20.1300.10 1 210 1.1E-45 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 Gene3D G3DSA:1.20.58.760 456 651 1.5E-64 T 12-10-2018 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 SUPERFAMILY SSF140990 460 641 5.62E-60 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 ProSitePatterns PS00674 AAA-protein family signature. 349 367 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 Gene3D G3DSA:3.40.50.300 198 380 1.6E-63 T 12-10-2018 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 156 639 9.8E-195 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 245 377 4.6E-43 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 Pfam PF01434 Peptidase family M41 440 639 9.3E-66 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 690 34.126 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 SMART SM00382 241 381 9.7E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 SUPERFAMILY SSF52540 202 450 7.59E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12850 f6d46d2db1f9ff756643f467e7d4993f 694 Gene3D G3DSA:1.10.8.60 381 455 2.5E-27 T 12-10-2018 AFR_39245 05b9da8c58a3db174b1866cdc0ae7825 239 SUPERFAMILY SSF53955 166 231 5.06E-8 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 207 224 0.0017 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 241 251 67.0 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 174 188 0.025 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 309 325 0.016 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 193 206 0.016 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 114 128 49.0 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 150 166 0.09 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 131 148 0.0043 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 290 306 0.97 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 340 354 0.0061 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 SUPERFAMILY SSF51120 241 327 1.15E-11 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_03680 fefdbdf068594d21a34efe685763fabe 392 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 204 222 - T 12-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site AFR_03680 fefdbdf068594d21a34efe685763fabe 392 SUPERFAMILY SSF51120 89 171 3.53E-15 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_03680 fefdbdf068594d21a34efe685763fabe 392 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 186 204 - T 12-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Gene3D G3DSA:2.150.10.10 234 340 1.2E-14 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_03680 fefdbdf068594d21a34efe685763fabe 392 PRINTS PR00313 NodO calcium binding signature 196 207 1.3E-9 T 12-10-2018 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 PRINTS PR00313 NodO calcium binding signature 217 225 1.3E-9 T 12-10-2018 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 PRINTS PR00313 NodO calcium binding signature 318 327 1.3E-9 T 12-10-2018 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 PRINTS PR00313 NodO calcium binding signature 291 299 1.3E-9 T 12-10-2018 AFR_03680 fefdbdf068594d21a34efe685763fabe 392 SUPERFAMILY SSF51120 173 230 8.5E-14 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_03680 fefdbdf068594d21a34efe685763fabe 392 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 195 213 - T 12-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Gene3D G3DSA:2.150.10.10 82 169 3.5E-13 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_03680 fefdbdf068594d21a34efe685763fabe 392 Gene3D G3DSA:2.150.10.10 170 233 6.2E-14 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFR_21060 9d1e2cf7a987a2abc6b9c04949c0731e 214 PIRSF PIRSF000847 20 208 1.9E-41 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFR_21060 9d1e2cf7a987a2abc6b9c04949c0731e 214 Pfam PF01066 CDP-alcohol phosphatidyltransferase 25 89 1.7E-15 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_21060 9d1e2cf7a987a2abc6b9c04949c0731e 214 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 67 89 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_21060 9d1e2cf7a987a2abc6b9c04949c0731e 214 Gene3D G3DSA:1.20.120.1760 15 159 3.0E-12 T 12-10-2018 AFR_21455 a6afcb70cea7aaa34ac84d20bb681a67 470 Gene3D G3DSA:3.90.1200.10 288 447 3.4E-9 T 12-10-2018 AFR_21455 a6afcb70cea7aaa34ac84d20bb681a67 470 SUPERFAMILY SSF53335 2 168 6.94E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_21455 a6afcb70cea7aaa34ac84d20bb681a67 470 SUPERFAMILY SSF56112 253 408 8.42E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_21455 a6afcb70cea7aaa34ac84d20bb681a67 470 Gene3D G3DSA:3.40.50.150 4 211 7.2E-29 T 12-10-2018 AFR_21455 a6afcb70cea7aaa34ac84d20bb681a67 470 Pfam PF01636 Phosphotransferase enzyme family 218 395 9.4E-11 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_21455 a6afcb70cea7aaa34ac84d20bb681a67 470 Pfam PF08241 Methyltransferase domain 37 125 3.6E-13 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_37775 98a2bf77fc68c8d65f4091b94f7cb2c8 487 SUPERFAMILY SSF52440 249 364 6.62E-21 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_37775 98a2bf77fc68c8d65f4091b94f7cb2c8 487 SUPERFAMILY SSF56059 35 481 1.24E-45 T 12-10-2018 AFR_37775 98a2bf77fc68c8d65f4091b94f7cb2c8 487 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 16 75 1.8E-7 T 12-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain AFR_37775 98a2bf77fc68c8d65f4091b94f7cb2c8 487 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 144 483 9.5E-84 T 12-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain AFR_37775 98a2bf77fc68c8d65f4091b94f7cb2c8 487 Gene3D G3DSA:3.30.1490.330 349 435 5.8E-16 T 12-10-2018 AFR_27010 0b29fa14906fe761b8347375af95af22 769 SUPERFAMILY SSF55073 347 498 2.28E-37 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_27010 0b29fa14906fe761b8347375af95af22 769 SUPERFAMILY SSF141868 513 762 1.83E-82 T 12-10-2018 IPR035919 EAL domain superfamily AFR_27010 0b29fa14906fe761b8347375af95af22 769 SMART SM00052 507 755 1.6E-106 T 12-10-2018 IPR001633 EAL domain AFR_27010 0b29fa14906fe761b8347375af95af22 769 Gene3D G3DSA:3.30.70.270 336 510 1.3E-44 T 12-10-2018 AFR_27010 0b29fa14906fe761b8347375af95af22 769 Pfam PF00990 Diguanylate cyclase, GGDEF domain 342 493 4.2E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_27010 0b29fa14906fe761b8347375af95af22 769 Gene3D G3DSA:3.20.20.450 511 768 4.8E-93 T 12-10-2018 IPR035919 EAL domain superfamily AFR_27010 0b29fa14906fe761b8347375af95af22 769 SMART SM00267 331 497 6.3E-46 T 12-10-2018 IPR000160 GGDEF domain AFR_27010 0b29fa14906fe761b8347375af95af22 769 Pfam PF00563 EAL domain 513 750 1.0E-71 T 12-10-2018 IPR001633 EAL domain AFR_27010 0b29fa14906fe761b8347375af95af22 769 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 339 495 5.6E-25 T 12-10-2018 IPR000160 GGDEF domain AFR_03655 3a6923f59f813fd9337530cc3d692684 123 Gene3D G3DSA:3.10.450.50 3 123 1.5E-31 T 12-10-2018 AFR_03655 3a6923f59f813fd9337530cc3d692684 123 SUPERFAMILY SSF54427 7 117 3.29E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_03655 3a6923f59f813fd9337530cc3d692684 123 Pfam PF12680 SnoaL-like domain 14 104 1.5E-8 T 12-10-2018 IPR037401 SnoaL-like domain AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 281 6.7E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 297 6.7E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 Pfam PF12852 Cupin 2 181 2.3E-36 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 Gene3D G3DSA:1.10.10.60 194 303 2.8E-25 T 12-10-2018 AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 SMART SM00342 214 297 2.1E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 Pfam PF12833 Helix-turn-helix domain 220 298 2.9E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 SUPERFAMILY SSF46689 250 299 6.27E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 SUPERFAMILY SSF46689 197 248 4.3E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 SUPERFAMILY SSF51215 35 104 5.89E-6 T 12-10-2018 IPR037923 Transcription regulator HTH-like AFR_12715 8e8911339e9c60a958309ad71c28a7b2 306 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 251 293 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_19590 42c38187035e09177d9b1a7d414c29df 178 SUPERFAMILY SSF48498 74 177 3.56E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_19590 42c38187035e09177d9b1a7d414c29df 178 SUPERFAMILY SSF46689 5 74 3.64E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19590 42c38187035e09177d9b1a7d414c29df 178 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 76 176 7.2E-18 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_19590 42c38187035e09177d9b1a7d414c29df 178 Gene3D G3DSA:1.10.357.10 5 177 1.7E-43 T 12-10-2018 AFR_19590 42c38187035e09177d9b1a7d414c29df 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 3.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_35310 5a7d6c47c62eab63c85bfe8b1b896c2e 98 Pfam PF13834 Domain of unknown function (DUF4193) 1 98 1.1E-40 T 12-10-2018 IPR025242 Protein of unknown function DUF4193 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 SUPERFAMILY SSF47413 4 48 5.89E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 Gene3D G3DSA:3.40.50.2300 60 321 3.4E-67 T 12-10-2018 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 Pfam PF13377 Periplasmic binding protein-like domain 173 329 2.1E-37 T 12-10-2018 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 Gene3D G3DSA:1.10.260.40 2 57 4.3E-16 T 12-10-2018 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 4.7E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 Gene3D G3DSA:3.40.50.2300 163 326 3.4E-67 T 12-10-2018 AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 SUPERFAMILY SSF53822 59 331 2.75E-60 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_01385 6ee1148095a5329e441a6a7c1565efbf 341 SMART SM00354 2 69 2.1E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_30310 e7fb0b1382024dbe275ce377b5b5cc35 394 Gene3D G3DSA:3.30.565.10 260 389 1.9E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30310 e7fb0b1382024dbe275ce377b5b5cc35 394 SUPERFAMILY SSF55874 267 387 1.32E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30310 e7fb0b1382024dbe275ce377b5b5cc35 394 Pfam PF07730 Histidine kinase 198 259 4.6E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_00595 b5c05661554c000a92b8c6873d14fcd1 222 Gene3D G3DSA:3.40.225.10 6 215 2.9E-44 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFR_00595 b5c05661554c000a92b8c6873d14fcd1 222 SUPERFAMILY SSF53639 7 201 1.16E-39 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFR_00595 b5c05661554c000a92b8c6873d14fcd1 222 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 191 1.3E-34 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFR_00595 b5c05661554c000a92b8c6873d14fcd1 222 SMART SM01007 10 194 5.4E-35 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFR_20965 ab399b34ee91d498add392a803de332d 407 Pfam PF05977 Transmembrane secretion effector 4 396 1.8E-27 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_20965 ab399b34ee91d498add392a803de332d 407 SUPERFAMILY SSF103473 9 396 7.85E-41 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_20965 ab399b34ee91d498add392a803de332d 407 Gene3D G3DSA:1.20.1250.20 8 394 1.0E-34 T 12-10-2018 AFR_12115 42576ef9441ff7d1ff86f5714f13832a 161 SUPERFAMILY SSF48371 19 151 2.17E-24 T 12-10-2018 IPR016024 Armadillo-type fold AFR_12115 42576ef9441ff7d1ff86f5714f13832a 161 Pfam PF13646 HEAT repeats 21 98 1.3E-13 T 12-10-2018 AFR_12115 42576ef9441ff7d1ff86f5714f13832a 161 SMART SM00567 E-Z type HEAT repeats 56 85 34.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_12115 42576ef9441ff7d1ff86f5714f13832a 161 SMART SM00567 E-Z type HEAT repeats 87 116 0.12 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_12115 42576ef9441ff7d1ff86f5714f13832a 161 SMART SM00567 E-Z type HEAT repeats 118 147 0.097 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_12115 42576ef9441ff7d1ff86f5714f13832a 161 SMART SM00567 E-Z type HEAT repeats 25 54 0.0038 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_12115 42576ef9441ff7d1ff86f5714f13832a 161 Gene3D G3DSA:1.25.10.10 3 160 9.1E-29 T 12-10-2018 IPR011989 Armadillo-like helical AFR_31450 45ddde416c5669b71da61589fa56bdb4 323 Gene3D G3DSA:2.60.120.10 170 281 4.1E-86 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_31450 45ddde416c5669b71da61589fa56bdb4 323 PIRSF PIRSF006232 24 319 1.3E-89 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFR_31450 45ddde416c5669b71da61589fa56bdb4 323 SUPERFAMILY SSF51182 26 317 2.66E-79 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_31450 45ddde416c5669b71da61589fa56bdb4 323 Gene3D G3DSA:2.60.120.10 39 307 4.1E-86 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_31450 45ddde416c5669b71da61589fa56bdb4 323 Pfam PF05726 Pirin C-terminal cupin domain 204 311 2.2E-30 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 AFR_31450 45ddde416c5669b71da61589fa56bdb4 323 Pfam PF02678 Pirin 44 148 1.2E-30 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFR_23285 ab61a56209ac787f5fcce79d48e69f8f 537 SUPERFAMILY SSF56024 311 460 4.49E-20 T 12-10-2018 AFR_23285 ab61a56209ac787f5fcce79d48e69f8f 537 Gene3D G3DSA:3.30.870.10 305 468 6.3E-16 T 12-10-2018 AFR_23285 ab61a56209ac787f5fcce79d48e69f8f 537 SUPERFAMILY SSF56024 22 234 2.54E-16 T 12-10-2018 AFR_23285 ab61a56209ac787f5fcce79d48e69f8f 537 Pfam PF13091 PLD-like domain 319 441 6.8E-10 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFR_23285 ab61a56209ac787f5fcce79d48e69f8f 537 Gene3D G3DSA:3.30.870.10 54 243 7.5E-14 T 12-10-2018 AFR_23285 ab61a56209ac787f5fcce79d48e69f8f 537 SMART SM00155 155 185 1.0 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFR_23285 ab61a56209ac787f5fcce79d48e69f8f 537 SMART SM00155 411 438 3.2E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFR_07785 8feb1475b99baadf51a11b1e99abb379 88 SUPERFAMILY SSF46992 3 86 3.92E-27 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_07785 8feb1475b99baadf51a11b1e99abb379 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 3.0E-25 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_07785 8feb1475b99baadf51a11b1e99abb379 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.119 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_07785 8feb1475b99baadf51a11b1e99abb379 88 Pfam PF01649 Ribosomal protein S20 2 83 6.1E-27 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_07785 8feb1475b99baadf51a11b1e99abb379 88 Gene3D G3DSA:1.20.58.110 1 87 2.6E-28 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_07785 8feb1475b99baadf51a11b1e99abb379 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 1.3E-23 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 Gene3D G3DSA:3.40.50.20 1 98 2.5E-27 T 12-10-2018 AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 Gene3D G3DSA:3.30.470.20 99 349 5.7E-90 T 12-10-2018 AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 SUPERFAMILY SSF56059 95 291 6.01E-61 T 12-10-2018 AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 SUPERFAMILY SSF51246 297 368 1.41E-16 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 SUPERFAMILY SSF52440 2 90 4.03E-22 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 Gene3D G3DSA:3.30.1490.20 110 171 5.7E-90 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 1 352 38.361 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 Pfam PF02222 ATP-grasp domain 104 271 4.1E-51 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AFR_05550 882a342fe83cc1786f60ac9ad803d024 371 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 1 356 1.3E-117 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 54 68 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 Pfam PF00107 Zinc-binding dehydrogenase 179 306 3.5E-20 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 172 200 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 Gene3D G3DSA:3.90.180.10 1 334 2.4E-96 T 12-10-2018 AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 SUPERFAMILY SSF51735 148 312 5.49E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 22 126 1.2E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 SUPERFAMILY SSF50129 2 169 4.41E-46 T 12-10-2018 IPR011032 GroES-like superfamily AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 SMART SM00829 3 343 0.004 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_27155 64d8d030406e91a3c8af4e41ba06a88b 345 Gene3D G3DSA:3.40.50.720 159 307 2.4E-96 T 12-10-2018 AFR_08395 97eb753943c8ed0f0ad978e7ee35229a 1046 Gene3D G3DSA:3.40.50.300 627 735 6.6E-10 T 12-10-2018 AFR_08395 97eb753943c8ed0f0ad978e7ee35229a 1046 Gene3D G3DSA:3.40.50.300 859 1023 1.5E-16 T 12-10-2018 AFR_08395 97eb753943c8ed0f0ad978e7ee35229a 1046 SUPERFAMILY SSF52540 47 284 2.05E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08395 97eb753943c8ed0f0ad978e7ee35229a 1046 SUPERFAMILY SSF52540 621 1011 7.32E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08395 97eb753943c8ed0f0ad978e7ee35229a 1046 SMART SM00382 655 982 6.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08395 97eb753943c8ed0f0ad978e7ee35229a 1046 Pfam PF01935 Domain of unknown function DUF87 638 700 2.7E-8 T 12-10-2018 IPR002789 Helicase HerA, central domain AFR_10325 2226bd350514f40284e70a34959d48fb 400 SUPERFAMILY SSF51905 4 376 7.77E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_10325 2226bd350514f40284e70a34959d48fb 400 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 36 4.5E-7 T 12-10-2018 AFR_10325 2226bd350514f40284e70a34959d48fb 400 Gene3D G3DSA:3.30.9.30 36 273 8.5E-65 T 12-10-2018 AFR_10325 2226bd350514f40284e70a34959d48fb 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 5.0E-17 T 12-10-2018 AFR_10325 2226bd350514f40284e70a34959d48fb 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 5.0E-17 T 12-10-2018 AFR_10325 2226bd350514f40284e70a34959d48fb 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 353 5.0E-17 T 12-10-2018 AFR_10325 2226bd350514f40284e70a34959d48fb 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 5.0E-17 T 12-10-2018 AFR_10325 2226bd350514f40284e70a34959d48fb 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 5.0E-17 T 12-10-2018 AFR_10325 2226bd350514f40284e70a34959d48fb 400 Pfam PF01494 FAD binding domain 137 351 9.1E-13 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_10325 2226bd350514f40284e70a34959d48fb 400 Gene3D G3DSA:3.50.50.60 5 353 8.5E-65 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 Gene3D G3DSA:3.40.50.720 3 290 3.3E-48 T 12-10-2018 AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.1E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.1E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 1.1E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 1.1E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 SUPERFAMILY SSF51735 8 269 3.13E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13605 93f1609899fc8b64595d896eb99a1c98 291 Pfam PF00106 short chain dehydrogenase 11 135 2.8E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_42970 0d54385c178d9752417b094c15db3c83 283 SUPERFAMILY SSF52540 24 272 2.66E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42970 0d54385c178d9752417b094c15db3c83 283 Gene3D G3DSA:3.40.50.300 20 277 1.1E-77 T 12-10-2018 AFR_42970 0d54385c178d9752417b094c15db3c83 283 Pfam PF13614 AAA domain 25 201 3.0E-59 T 12-10-2018 IPR025669 AAA domain AFR_01355 a48fcbfa034e6b8605f4f4b5d074a8ef 570 Gene3D G3DSA:3.40.50.300 306 570 3.6E-67 T 12-10-2018 AFR_01355 a48fcbfa034e6b8605f4f4b5d074a8ef 570 SUPERFAMILY SSF52540 305 565 1.59E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01355 a48fcbfa034e6b8605f4f4b5d074a8ef 570 Pfam PF00005 ABC transporter 331 490 3.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01355 a48fcbfa034e6b8605f4f4b5d074a8ef 570 SUPERFAMILY SSF90123 2 279 3.79E-15 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_01355 a48fcbfa034e6b8605f4f4b5d074a8ef 570 Gene3D G3DSA:1.20.1560.10 1 290 1.2E-12 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_01355 a48fcbfa034e6b8605f4f4b5d074a8ef 570 SMART SM00382 340 541 9.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41395 4a1838660b5d4dff1ca6d3ff8a575b43 295 Gene3D G3DSA:3.40.50.720 12 171 6.6E-31 T 12-10-2018 AFR_41395 4a1838660b5d4dff1ca6d3ff8a575b43 295 SUPERFAMILY SSF51735 16 171 1.46E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41395 4a1838660b5d4dff1ca6d3ff8a575b43 295 Pfam PF10727 Rossmann-like domain 9 117 1.1E-35 T 12-10-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain AFR_41395 4a1838660b5d4dff1ca6d3ff8a575b43 295 Pfam PF10728 Domain of unknown function (DUF2520) 146 264 9.1E-38 T 12-10-2018 IPR018931 Domain of unknown function DUF2520 AFR_41395 4a1838660b5d4dff1ca6d3ff8a575b43 295 Gene3D G3DSA:1.10.1040.20 173 268 7.7E-17 T 12-10-2018 IPR037108 TM1727-like, C-terminal domain superfamily AFR_41395 4a1838660b5d4dff1ca6d3ff8a575b43 295 SUPERFAMILY SSF48179 174 270 1.87E-24 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_13890 879a5030e0c48cb6ac989bd2a71898b7 262 SUPERFAMILY SSF53335 1 147 4.37E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_13890 879a5030e0c48cb6ac989bd2a71898b7 262 Pfam PF13649 Methyltransferase domain 26 110 5.8E-13 T 12-10-2018 AFR_13890 879a5030e0c48cb6ac989bd2a71898b7 262 Gene3D G3DSA:3.40.50.150 1 128 3.2E-23 T 12-10-2018 AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 SUPERFAMILY SSF46894 128 201 2.35E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 SMART SM00448 2 115 1.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 6.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 SMART SM00421 138 195 6.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 SUPERFAMILY SSF52172 2 129 1.71E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17650 e38df9a9b62dad0ddddb11369625b369 206 Gene3D G3DSA:3.40.50.12740 2 201 3.8E-54 T 12-10-2018 AFR_41970 75185dcbbe13c8dd1822981d05b86e45 1623 Pfam PF07728 AAA domain (dynein-related subfamily) 1260 1385 1.4E-5 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFR_41970 75185dcbbe13c8dd1822981d05b86e45 1623 Pfam PF12458 ATPase involved in DNA repair 28 475 2.0E-219 T 12-10-2018 IPR020958 Domain of unknown function DUF3686 AFR_41970 75185dcbbe13c8dd1822981d05b86e45 1623 SUPERFAMILY SSF52540 1253 1405 2.57E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41970 75185dcbbe13c8dd1822981d05b86e45 1623 Gene3D G3DSA:3.40.50.300 1250 1408 2.8E-13 T 12-10-2018 AFR_36975 64383f00bb1fe4ca77bff38d0a425cfe 497 Gene3D G3DSA:3.90.1300.10 3 486 1.1E-185 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_36975 64383f00bb1fe4ca77bff38d0a425cfe 497 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 484 90.574 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_36975 64383f00bb1fe4ca77bff38d0a425cfe 497 SUPERFAMILY SSF75304 3 489 1.96E-160 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_36975 64383f00bb1fe4ca77bff38d0a425cfe 497 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 483 1.6E-181 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_36975 64383f00bb1fe4ca77bff38d0a425cfe 497 Pfam PF01425 Amidase 25 471 3.2E-152 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_36975 64383f00bb1fe4ca77bff38d0a425cfe 497 ProSitePatterns PS00571 Amidases signature. 153 184 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 Gene3D G3DSA:1.10.1740.10 2 100 1.5E-18 T 12-10-2018 AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 33 65 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 161 1.3E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 SUPERFAMILY SSF88946 4 95 2.75E-24 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 Gene3D G3DSA:1.10.10.10 101 169 4.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 SUPERFAMILY SSF88659 100 163 2.06E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 Pfam PF04545 Sigma-70, region 4 111 160 5.9E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_02410 bf15bf30ac91fe61153710fc234317b4 169 Pfam PF04542 Sigma-70 region 2 11 80 2.1E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_17605 08d681ad0e539cab2df76332e0147ddd 408 Gene3D G3DSA:3.30.420.40 215 381 1.5E-69 T 12-10-2018 AFR_17605 08d681ad0e539cab2df76332e0147ddd 408 SUPERFAMILY SSF46785 16 79 2.34E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17605 08d681ad0e539cab2df76332e0147ddd 408 Pfam PF09339 IclR helix-turn-helix domain 23 65 1.3E-5 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_17605 08d681ad0e539cab2df76332e0147ddd 408 SUPERFAMILY SSF53067 89 398 8.65E-43 T 12-10-2018 AFR_17605 08d681ad0e539cab2df76332e0147ddd 408 Pfam PF00480 ROK family 90 396 3.7E-41 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_17605 08d681ad0e539cab2df76332e0147ddd 408 Gene3D G3DSA:3.30.420.40 96 390 1.5E-69 T 12-10-2018 AFR_17605 08d681ad0e539cab2df76332e0147ddd 408 Gene3D G3DSA:1.10.10.10 6 84 2.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28610 b4d20575221238007e627f34653a32a5 225 SMART SM00862 143 219 3.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28610 b4d20575221238007e627f34653a32a5 225 SUPERFAMILY SSF46894 121 220 9.07E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28610 b4d20575221238007e627f34653a32a5 225 SMART SM00448 1 108 1.7E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28610 b4d20575221238007e627f34653a32a5 225 SUPERFAMILY SSF52172 1 119 5.98E-39 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28610 b4d20575221238007e627f34653a32a5 225 Gene3D G3DSA:3.40.50.2300 1 112 2.6E-34 T 12-10-2018 AFR_28610 b4d20575221238007e627f34653a32a5 225 Pfam PF00072 Response regulator receiver domain 1 109 1.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28610 b4d20575221238007e627f34653a32a5 225 Gene3D G3DSA:1.10.10.10 113 223 1.5E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28610 b4d20575221238007e627f34653a32a5 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 1.5E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40550 7583980c97893e0664f6a3b324fcaca1 329 Pfam PF13469 Sulfotransferase family 1 193 2.3E-32 T 12-10-2018 AFR_40550 7583980c97893e0664f6a3b324fcaca1 329 SUPERFAMILY SSF52540 1 255 4.25E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40550 7583980c97893e0664f6a3b324fcaca1 329 Gene3D G3DSA:3.40.50.300 1 263 3.8E-53 T 12-10-2018 AFR_34720 45693ce5ed6ed06a98f4e6edd4dad535 305 Gene3D G3DSA:1.10.10.10 3 84 2.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34720 45693ce5ed6ed06a98f4e6edd4dad535 305 Pfam PF01380 SIS domain 135 263 6.7E-21 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_34720 45693ce5ed6ed06a98f4e6edd4dad535 305 SUPERFAMILY SSF46689 8 79 6.63E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_34720 45693ce5ed6ed06a98f4e6edd4dad535 305 Gene3D G3DSA:3.40.50.10490 103 287 2.2E-43 T 12-10-2018 AFR_34720 45693ce5ed6ed06a98f4e6edd4dad535 305 SUPERFAMILY SSF53697 111 291 8.34E-39 T 12-10-2018 AFR_34720 45693ce5ed6ed06a98f4e6edd4dad535 305 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 78 4.6E-17 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AFR_38890 a53a943aa1a9258c646006738b207f7c 258 Gene3D G3DSA:3.40.50.720 2 249 3.0E-58 T 12-10-2018 AFR_38890 a53a943aa1a9258c646006738b207f7c 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_38890 a53a943aa1a9258c646006738b207f7c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.6E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38890 a53a943aa1a9258c646006738b207f7c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.6E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38890 a53a943aa1a9258c646006738b207f7c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.6E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38890 a53a943aa1a9258c646006738b207f7c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.6E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38890 a53a943aa1a9258c646006738b207f7c 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.6E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38890 a53a943aa1a9258c646006738b207f7c 258 Pfam PF00106 short chain dehydrogenase 5 186 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38890 a53a943aa1a9258c646006738b207f7c 258 SUPERFAMILY SSF51735 5 244 9.74E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16280 0d7f7d58cdbce853387a37a87175d7aa 272 Gene3D G3DSA:3.90.1580.10 45 267 1.4E-16 T 12-10-2018 AFR_16280 0d7f7d58cdbce853387a37a87175d7aa 272 Pfam PF03781 Sulfatase-modifying factor enzyme 1 156 184 8.9E-6 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFR_16280 0d7f7d58cdbce853387a37a87175d7aa 272 SUPERFAMILY SSF56436 56 266 3.06E-24 T 12-10-2018 IPR016187 C-type lectin fold AFR_07720 ccf625ed61cd1cd1bddd9c88c9dfb27c 201 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 5 194 29.792 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFR_07720 ccf625ed61cd1cd1bddd9c88c9dfb27c 201 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 9 193 5.5E-51 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFR_07720 ccf625ed61cd1cd1bddd9c88c9dfb27c 201 Pfam PF01467 Cytidylyltransferase-like 9 168 4.8E-27 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_07720 ccf625ed61cd1cd1bddd9c88c9dfb27c 201 Gene3D G3DSA:3.40.50.620 3 198 2.0E-60 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_07720 ccf625ed61cd1cd1bddd9c88c9dfb27c 201 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 7 69 1.6E-12 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_07720 ccf625ed61cd1cd1bddd9c88c9dfb27c 201 SUPERFAMILY SSF52374 3 194 2.0E-52 T 12-10-2018 AFR_02020 b44de6179d7e7386fcccc926299c57dc 297 SUPERFAMILY SSF47413 13 73 7.6E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_02020 b44de6179d7e7386fcccc926299c57dc 297 SMART SM00530 17 72 1.2E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_02020 b44de6179d7e7386fcccc926299c57dc 297 Pfam PF13560 Helix-turn-helix domain 17 75 2.6E-11 T 12-10-2018 AFR_02020 b44de6179d7e7386fcccc926299c57dc 297 Gene3D G3DSA:1.10.260.40 2 77 3.8E-10 T 12-10-2018 AFR_27725 8d0ac8e69887bde530988250eb022945 625 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 58 2.0E-20 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFR_27725 8d0ac8e69887bde530988250eb022945 625 Gene3D G3DSA:3.40.50.12780 38 494 3.3E-107 T 12-10-2018 AFR_27725 8d0ac8e69887bde530988250eb022945 625 Pfam PF00501 AMP-binding enzyme 64 501 6.0E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_27725 8d0ac8e69887bde530988250eb022945 625 Gene3D G3DSA:3.30.300.30 497 621 8.6E-24 T 12-10-2018 AFR_27725 8d0ac8e69887bde530988250eb022945 625 SUPERFAMILY SSF56801 3 619 1.22E-164 T 12-10-2018 AFR_27725 8d0ac8e69887bde530988250eb022945 625 Pfam PF13193 AMP-binding enzyme C-terminal domain 511 589 1.2E-24 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_27725 8d0ac8e69887bde530988250eb022945 625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Gene3D G3DSA:3.10.129.110 1178 1430 7.4E-17 T 12-10-2018 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 555 822 2.3E-12 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain AFR_39760 7f9243706e825a41302fd014f0843e35 1669 SUPERFAMILY SSF56214 1567 1633 4.53E-12 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 417 469 1.0E-7 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Gene3D G3DSA:3.30.70.250 648 715 1.8E-40 T 12-10-2018 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Gene3D G3DSA:3.90.470.20 1460 1563 3.9E-7 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Pfam PF14765 Polyketide synthase dehydratase 1176 1433 5.2E-18 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1568 1622 7.9E-8 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Gene3D G3DSA:3.40.366.10 587 799 1.8E-40 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site AFR_39760 7f9243706e825a41302fd014f0843e35 1669 SUPERFAMILY SSF53901 2 457 1.47E-70 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 SMART SM00825 Beta-ketoacyl synthase 4 461 1.4E-99 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFR_39760 7f9243706e825a41302fd014f0843e35 1669 SUPERFAMILY SSF52151 551 817 2.51E-28 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 411 4.4E-31 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Gene3D G3DSA:3.90.470.20 1568 1651 3.6E-11 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 284 2.1E-62 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFR_39760 7f9243706e825a41302fd014f0843e35 1669 SUPERFAMILY SSF55048 653 713 2.35E-5 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Pfam PF00698 Acyl transferase domain 608 796 6.4E-17 T 12-10-2018 IPR014043 Acyl transferase AFR_39760 7f9243706e825a41302fd014f0843e35 1669 Gene3D G3DSA:3.40.47.10 1 503 5.9E-149 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_30210 f608d67601e86522a9867dabbf207a2b 417 SUPERFAMILY SSF69864 174 408 5.49E-44 T 12-10-2018 AFR_30210 f608d67601e86522a9867dabbf207a2b 417 Pfam PF00764 Arginosuccinate synthase 7 374 6.3E-79 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_30210 f608d67601e86522a9867dabbf207a2b 417 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 373 3.2E-80 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_30210 f608d67601e86522a9867dabbf207a2b 417 SUPERFAMILY SSF52402 3 202 1.63E-36 T 12-10-2018 AFR_30210 f608d67601e86522a9867dabbf207a2b 417 Gene3D G3DSA:3.40.50.620 1 174 4.2E-47 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_30210 f608d67601e86522a9867dabbf207a2b 417 Gene3D G3DSA:3.90.1260.10 175 411 1.5E-51 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_30210 f608d67601e86522a9867dabbf207a2b 417 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFR_21190 3c049c9be33c45122d6df8c76eecb16f 331 SUPERFAMILY SSF51430 13 327 3.8E-88 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_21190 3c049c9be33c45122d6df8c76eecb16f 331 Gene3D G3DSA:3.20.20.100 15 330 3.3E-111 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_21190 3c049c9be33c45122d6df8c76eecb16f 331 Pfam PF00248 Aldo/keto reductase family 28 326 6.2E-68 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.2E-8 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.2E-8 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 Gene3D G3DSA:3.40.50.880 1 189 2.1E-63 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 4.2E-14 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 4.2E-14 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 4.2E-14 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00097 Anthranilate synthase component II signature 75 86 2.9E-35 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.9E-35 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00097 Anthranilate synthase component II signature 48 57 2.9E-35 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00097 Anthranilate synthase component II signature 100 108 2.9E-35 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00097 Anthranilate synthase component II signature 165 178 2.9E-35 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 PRINTS PR00097 Anthranilate synthase component II signature 120 132 2.9E-35 T 12-10-2018 AFR_00300 f9bacecb78d0af74164d937a7d373426 216 SUPERFAMILY SSF52317 2 188 7.58E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_00300 f9bacecb78d0af74164d937a7d373426 216 Pfam PF00117 Glutamine amidotransferase class-I 4 186 9.4E-54 T 12-10-2018 IPR017926 Glutamine amidotransferase AFR_00300 f9bacecb78d0af74164d937a7d373426 216 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 186 2.3E-70 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_18160 8fe086ad875a8322c4a93b92bbec4880 707 SUPERFAMILY SSF81296 608 706 3.78E-24 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_18160 8fe086ad875a8322c4a93b92bbec4880 707 Pfam PF09118 Domain of unknown function (DUF1929) 612 706 3.0E-22 T 12-10-2018 IPR015202 Galactose oxidase-like, Early set domain AFR_18160 8fe086ad875a8322c4a93b92bbec4880 707 Gene3D G3DSA:2.60.40.10 612 707 6.7E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_18160 8fe086ad875a8322c4a93b92bbec4880 707 SUPERFAMILY SSF50965 399 608 3.4E-15 T 12-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller AFR_18160 8fe086ad875a8322c4a93b92bbec4880 707 Gene3D G3DSA:2.130.10.80 219 611 2.5E-77 T 12-10-2018 IPR037293 Galactose oxidase, central domain superfamily AFR_18160 8fe086ad875a8322c4a93b92bbec4880 707 Gene3D G3DSA:2.60.120.260 48 210 1.1E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_18160 8fe086ad875a8322c4a93b92bbec4880 707 SUPERFAMILY SSF117281 224 438 1.28E-17 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFR_03430 bcdd01110a31836eaaed364e65cf3caf 403 SUPERFAMILY SSF55874 287 394 7.02E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03430 bcdd01110a31836eaaed364e65cf3caf 403 Pfam PF07730 Histidine kinase 194 259 3.6E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_03430 bcdd01110a31836eaaed364e65cf3caf 403 Gene3D G3DSA:3.30.565.10 273 395 3.3E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_29670 b5dde72d524fe6a0126489573ba49bb4 148 PRINTS PR00502 NUDIX hydrolase family signature 34 48 3.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_29670 b5dde72d524fe6a0126489573ba49bb4 148 PRINTS PR00502 NUDIX hydrolase family signature 49 64 3.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_29670 b5dde72d524fe6a0126489573ba49bb4 148 SUPERFAMILY SSF55811 3 127 3.93E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_29670 b5dde72d524fe6a0126489573ba49bb4 148 Pfam PF00293 NUDIX domain 6 122 1.2E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_29670 b5dde72d524fe6a0126489573ba49bb4 148 Gene3D G3DSA:3.90.79.10 1 138 3.2E-23 T 12-10-2018 AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 Pfam PF06441 Epoxide hydrolase N terminus 2 104 4.8E-32 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 PRINTS PR00412 Epoxide hydrolase signature 337 359 4.9E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 PRINTS PR00412 Epoxide hydrolase signature 159 172 4.9E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 PRINTS PR00412 Epoxide hydrolase signature 173 186 4.9E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 PRINTS PR00412 Epoxide hydrolase signature 95 113 4.9E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 PIRSF PIRSF001112 1 365 2.1E-113 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 SUPERFAMILY SSF53474 2 361 1.62E-97 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33570 a20faf258c7c25e1525b869858bfa1a5 365 Gene3D G3DSA:3.40.50.1820 1 365 1.3E-133 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29825 718b5db9268a4ae927f82209d7be7731 122 Pfam PF14078 Domain of unknown function (DUF4259) 2 35 6.0E-5 T 12-10-2018 IPR025355 Protein of unknown function DUF4259 AFR_22870 e364b222f22c89231870f6d26d12682b 117 SMART SM00418 15 105 2.5E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_22870 e364b222f22c89231870f6d26d12682b 117 SUPERFAMILY SSF46785 11 96 2.54E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_22870 e364b222f22c89231870f6d26d12682b 117 Gene3D G3DSA:1.10.10.10 10 104 1.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22870 e364b222f22c89231870f6d26d12682b 117 Pfam PF01022 Bacterial regulatory protein, arsR family 22 67 9.9E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_36355 de0406d0912e381717597c19b2473cb4 468 Gene3D G3DSA:2.130.10.10 52 299 3.0E-15 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_36355 de0406d0912e381717597c19b2473cb4 468 Pfam PF13360 PQQ-like domain 199 427 2.8E-9 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_36355 de0406d0912e381717597c19b2473cb4 468 SUPERFAMILY SSF50998 113 396 7.22E-13 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_02660 d235443805b3edf3578ce1226a255634 101 Gene3D G3DSA:1.10.287.1080 5 99 2.8E-17 T 12-10-2018 AFR_02660 d235443805b3edf3578ce1226a255634 101 SUPERFAMILY SSF101386 15 96 1.96E-15 T 12-10-2018 AFR_02660 d235443805b3edf3578ce1226a255634 101 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 31 88 1.0E-4 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFR_36595 54e3482b03d54e039c421951cb5616bc 155 Gene3D G3DSA:3.40.630.30 7 155 1.6E-36 T 12-10-2018 AFR_36595 54e3482b03d54e039c421951cb5616bc 155 Pfam PF00583 Acetyltransferase (GNAT) family 38 133 3.4E-16 T 12-10-2018 IPR000182 GNAT domain AFR_36595 54e3482b03d54e039c421951cb5616bc 155 SUPERFAMILY SSF55729 12 144 3.77E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05545 14f6f181b0faa33fee1fae055d1bc584 662 PIRSF PIRSF006402 1 662 4.4E-191 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 AFR_05545 14f6f181b0faa33fee1fae055d1bc584 662 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 466 502 0.05 T 12-10-2018 AFR_05545 14f6f181b0faa33fee1fae055d1bc584 662 Pfam PF03190 Protein of unknown function, DUF255 3 157 5.4E-69 T 12-10-2018 IPR004879 Domain of unknown function DUF255 AFR_05545 14f6f181b0faa33fee1fae055d1bc584 662 Gene3D G3DSA:1.50.10.10 205 331 1.4E-5 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_05545 14f6f181b0faa33fee1fae055d1bc584 662 SUPERFAMILY SSF52833 2 134 1.59E-28 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_05545 14f6f181b0faa33fee1fae055d1bc584 662 SUPERFAMILY SSF48208 181 524 8.5E-60 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_05545 14f6f181b0faa33fee1fae055d1bc584 662 Gene3D G3DSA:3.40.30.10 1 161 1.7E-62 T 12-10-2018 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 SUPERFAMILY SSF52172 1 115 1.99E-27 T 12-10-2018 IPR011006 CheY-like superfamily AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 Pfam PF00072 Response regulator receiver domain 1 110 4.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 SUPERFAMILY SSF46894 132 208 2.35E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 SMART SM00448 1 110 7.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 Gene3D G3DSA:3.40.50.12740 1 208 4.4E-58 T 12-10-2018 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 SMART SM00421 146 203 3.2E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 2.3E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38170 0dd928807f2cd8fe7309fd1e55123ff8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_15845 248cc2b508bdc7a47100c415ed393ddf 334 Pfam PF00248 Aldo/keto reductase family 18 305 8.4E-66 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_15845 248cc2b508bdc7a47100c415ed393ddf 334 PRINTS PR00069 Aldo-keto reductase signature 104 122 6.5E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_15845 248cc2b508bdc7a47100c415ed393ddf 334 PRINTS PR00069 Aldo-keto reductase signature 42 66 6.5E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_15845 248cc2b508bdc7a47100c415ed393ddf 334 PRINTS PR00069 Aldo-keto reductase signature 135 152 6.5E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_15845 248cc2b508bdc7a47100c415ed393ddf 334 SUPERFAMILY SSF51430 1 307 5.63E-91 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_15845 248cc2b508bdc7a47100c415ed393ddf 334 Gene3D G3DSA:3.20.20.100 1 318 4.5E-107 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_08640 e588cbdf2603d0714715ff205191facf 306 SUPERFAMILY SSF101898 38 282 3.66E-20 T 12-10-2018 AFR_08640 e588cbdf2603d0714715ff205191facf 306 Gene3D G3DSA:2.130.10.10 17 283 1.7E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_01360 06bcd5b397d126d99afaab3a40b35793 182 SUPERFAMILY SSF47413 52 119 1.36E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_01360 06bcd5b397d126d99afaab3a40b35793 182 Pfam PF13560 Helix-turn-helix domain 78 118 2.4E-6 T 12-10-2018 AFR_09535 e47cabc594eadd55608507cb37481975 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 1.3E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_09535 e47cabc594eadd55608507cb37481975 222 SUPERFAMILY SSF46894 145 215 9.52E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_09535 e47cabc594eadd55608507cb37481975 222 Pfam PF00072 Response regulator receiver domain 13 124 1.7E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_09535 e47cabc594eadd55608507cb37481975 222 SUPERFAMILY SSF52172 10 132 2.56E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_09535 e47cabc594eadd55608507cb37481975 222 SMART SM00448 11 124 2.2E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_09535 e47cabc594eadd55608507cb37481975 222 SMART SM00421 151 208 7.8E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_09535 e47cabc594eadd55608507cb37481975 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_09535 e47cabc594eadd55608507cb37481975 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_09535 e47cabc594eadd55608507cb37481975 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_09535 e47cabc594eadd55608507cb37481975 222 Gene3D G3DSA:3.40.50.12740 11 214 5.7E-62 T 12-10-2018 AFR_33410 d40a9f99027f19f9c5742f890c326e00 250 Pfam PF12697 Alpha/beta hydrolase family 39 231 2.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_33410 d40a9f99027f19f9c5742f890c326e00 250 Gene3D G3DSA:3.40.50.1820 2 243 7.3E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33410 d40a9f99027f19f9c5742f890c326e00 250 SUPERFAMILY SSF53474 6 244 7.94E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_06980 837afb7c124ccd2c2e8bb5c199f6c83b 199 SUPERFAMILY SSF52540 18 190 3.13E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06980 837afb7c124ccd2c2e8bb5c199f6c83b 199 Gene3D G3DSA:3.40.50.300 12 193 1.3E-17 T 12-10-2018 AFR_06980 837afb7c124ccd2c2e8bb5c199f6c83b 199 Pfam PF03029 Conserved hypothetical ATP binding protein 23 185 2.5E-24 T 12-10-2018 IPR004130 GPN-loop GTPase AFR_28245 26b5ae7a06c9a8858c308b7ee4eb0e6a 208 Pfam PF07690 Major Facilitator Superfamily 28 199 1.0E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_28245 26b5ae7a06c9a8858c308b7ee4eb0e6a 208 SUPERFAMILY SSF103473 5 199 1.96E-22 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_28245 26b5ae7a06c9a8858c308b7ee4eb0e6a 208 Gene3D G3DSA:1.20.1250.20 15 206 8.2E-18 T 12-10-2018 AFR_10895 7f444ef15419608a821167f1690131dc 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 8.4E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10895 7f444ef15419608a821167f1690131dc 192 SUPERFAMILY SSF46689 3 74 4.05E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_10895 7f444ef15419608a821167f1690131dc 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10895 7f444ef15419608a821167f1690131dc 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10895 7f444ef15419608a821167f1690131dc 192 Gene3D G3DSA:1.10.357.10 2 192 1.0E-54 T 12-10-2018 AFR_10895 7f444ef15419608a821167f1690131dc 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_10895 7f444ef15419608a821167f1690131dc 192 SUPERFAMILY SSF48498 81 191 7.95E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 Pfam PF13365 Trypsin-like peptidase domain 70 230 1.2E-32 T 12-10-2018 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 Pfam PF13180 PDZ domain 271 351 8.2E-22 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 PRINTS PR00834 HtrA/DegQ protease family signature 201 218 1.2E-35 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 PRINTS PR00834 HtrA/DegQ protease family signature 300 312 1.2E-35 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 PRINTS PR00834 HtrA/DegQ protease family signature 102 122 1.2E-35 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 PRINTS PR00834 HtrA/DegQ protease family signature 79 91 1.2E-35 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 PRINTS PR00834 HtrA/DegQ protease family signature 223 240 1.2E-35 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 SUPERFAMILY SSF50156 255 351 8.81E-23 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 SMART SM00228 271 342 1.1E-15 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 SUPERFAMILY SSF50494 48 267 2.38E-55 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 Gene3D G3DSA:2.40.10.10 43 132 5.2E-25 T 12-10-2018 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 Gene3D G3DSA:2.40.10.10 133 267 4.7E-39 T 12-10-2018 AFR_37935 749ba4e44895bc1ca2b914e7c4900403 355 Gene3D G3DSA:2.30.42.10 268 355 1.9E-24 T 12-10-2018 AFR_18745 95549833d6324fa2f12c07f8f75af49a 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 8.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18745 95549833d6324fa2f12c07f8f75af49a 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 8.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18745 95549833d6324fa2f12c07f8f75af49a 223 SUPERFAMILY SSF48498 96 207 1.02E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_18745 95549833d6324fa2f12c07f8f75af49a 223 SUPERFAMILY SSF46689 16 93 1.16E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_18745 95549833d6324fa2f12c07f8f75af49a 223 Gene3D G3DSA:1.10.357.10 13 213 1.9E-32 T 12-10-2018 AFR_18745 95549833d6324fa2f12c07f8f75af49a 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 74 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29605 4dc368e4843d7283210ad1d4f5436a07 1193 SUPERFAMILY SSF53335 56 471 2.99E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_29605 4dc368e4843d7283210ad1d4f5436a07 1193 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 359 365 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFR_29605 4dc368e4843d7283210ad1d4f5436a07 1193 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 199 215 3.3E-6 T 12-10-2018 AFR_29605 4dc368e4843d7283210ad1d4f5436a07 1193 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 356 368 3.3E-6 T 12-10-2018 AFR_29605 4dc368e4843d7283210ad1d4f5436a07 1193 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 230 244 3.3E-6 T 12-10-2018 AFR_29605 4dc368e4843d7283210ad1d4f5436a07 1193 Gene3D G3DSA:3.40.50.150 178 483 2.1E-38 T 12-10-2018 AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 Pfam PF08281 Sigma-70, region 4 103 153 2.0E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 SUPERFAMILY SSF88659 98 157 7.85E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 Pfam PF04542 Sigma-70 region 2 13 77 1.5E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 6 158 6.9E-44 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 155 4.8E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 Gene3D G3DSA:1.10.1740.10 3 75 3.5E-6 T 12-10-2018 AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 Gene3D G3DSA:1.10.10.10 76 160 7.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16755 f46abf6e4d41e853a8b14d8b3cbe5eb8 172 SUPERFAMILY SSF88946 9 94 1.92E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_31325 b41a881e43089103fb6e90ef497dc9ee 106 SUPERFAMILY SSF55961 2 97 1.28E-9 T 12-10-2018 AFR_31325 b41a881e43089103fb6e90ef497dc9ee 106 Gene3D G3DSA:3.30.530.20 1 104 1.3E-6 T 12-10-2018 IPR023393 START-like domain superfamily AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 Gene3D G3DSA:1.10.10.10 103 162 1.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 Pfam PF08281 Sigma-70, region 4 106 156 4.9E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 SUPERFAMILY SSF88659 103 160 6.54E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 Gene3D G3DSA:1.10.1740.10 1 86 3.8E-10 T 12-10-2018 AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 8.5E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 SUPERFAMILY SSF88946 5 85 3.14E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 Pfam PF04542 Sigma-70 region 2 13 80 1.6E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_18900 4cc2d7909de249b2cae15069cf186a4b 175 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 160 4.7E-43 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_27295 8cc4f2e5205884cf5d04e9501c6a47ad 282 Gene3D G3DSA:3.40.50.150 31 221 6.5E-35 T 12-10-2018 AFR_27295 8cc4f2e5205884cf5d04e9501c6a47ad 282 Pfam PF08241 Methyltransferase domain 49 145 8.9E-16 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_27295 8cc4f2e5205884cf5d04e9501c6a47ad 282 SUPERFAMILY SSF53335 25 243 5.58E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_06205 54ff048da40f5072d851e29a8a280040 1413 SMART SM00382 340 540 4.0E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_06205 54ff048da40f5072d851e29a8a280040 1413 Pfam PF13087 AAA domain 1065 1249 1.8E-17 T 12-10-2018 AFR_06205 54ff048da40f5072d851e29a8a280040 1413 Pfam PF13604 AAA domain 328 390 2.2E-7 T 12-10-2018 AFR_06205 54ff048da40f5072d851e29a8a280040 1413 SUPERFAMILY SSF52980 1287 1361 6.43E-6 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_06205 54ff048da40f5072d851e29a8a280040 1413 SUPERFAMILY SSF52540 326 1249 6.36E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06205 54ff048da40f5072d851e29a8a280040 1413 Gene3D G3DSA:3.40.50.300 1084 1275 1.7E-28 T 12-10-2018 AFR_06205 54ff048da40f5072d851e29a8a280040 1413 Gene3D G3DSA:3.40.50.300 904 1080 1.6E-10 T 12-10-2018 AFR_06205 54ff048da40f5072d851e29a8a280040 1413 Gene3D G3DSA:3.40.50.300 277 472 4.3E-16 T 12-10-2018 AFR_06205 54ff048da40f5072d851e29a8a280040 1413 Gene3D G3DSA:3.40.960.10 1287 1389 1.1E-15 T 12-10-2018 AFR_37555 3c6a8500d840758dc211259689d201ad 463 ProSitePatterns PS00455 Putative AMP-binding domain signature. 133 144 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_37555 3c6a8500d840758dc211259689d201ad 463 SUPERFAMILY SSF56801 10 461 1.83E-95 T 12-10-2018 AFR_37555 3c6a8500d840758dc211259689d201ad 463 Pfam PF13193 AMP-binding enzyme C-terminal domain 381 455 2.1E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_37555 3c6a8500d840758dc211259689d201ad 463 Gene3D G3DSA:3.30.300.30 366 463 4.2E-21 T 12-10-2018 AFR_37555 3c6a8500d840758dc211259689d201ad 463 Gene3D G3DSA:3.40.50.12780 6 364 9.3E-66 T 12-10-2018 AFR_37555 3c6a8500d840758dc211259689d201ad 463 Pfam PF00501 AMP-binding enzyme 122 371 1.2E-43 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_37555 3c6a8500d840758dc211259689d201ad 463 Pfam PF00501 AMP-binding enzyme 19 99 8.6E-10 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_04775 d1379c5c0decf9657afa93b71b76d480 206 Gene3D G3DSA:3.40.50.300 11 196 3.7E-15 T 12-10-2018 AFR_04775 d1379c5c0decf9657afa93b71b76d480 206 SUPERFAMILY SSF52540 19 190 3.06E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04775 d1379c5c0decf9657afa93b71b76d480 206 Pfam PF03029 Conserved hypothetical ATP binding protein 23 191 7.6E-25 T 12-10-2018 IPR004130 GPN-loop GTPase AFR_36330 b96df7dc424086447aad9858f9e0b4de 187 Pfam PF00886 Ribosomal protein S16 9 67 3.1E-23 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36330 b96df7dc424086447aad9858f9e0b4de 187 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.181 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36330 b96df7dc424086447aad9858f9e0b4de 187 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.9E-31 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36330 b96df7dc424086447aad9858f9e0b4de 187 SUPERFAMILY SSF54565 2 87 5.36E-32 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36330 b96df7dc424086447aad9858f9e0b4de 187 Gene3D G3DSA:3.30.1320.10 1 115 2.1E-30 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 SUPERFAMILY SSF50249 3 100 5.33E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 SUPERFAMILY SSF55681 111 578 2.7E-101 T 12-10-2018 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 Gene3D G3DSA:3.30.1360.30 269 415 3.2E-180 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 Gene3D G3DSA:3.30.930.10 115 570 3.2E-180 T 12-10-2018 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 Pfam PF01336 OB-fold nucleic acid binding domain 19 96 1.6E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 513 527 1.7E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 1.7E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 1.7E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 469 485 1.7E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 Pfam PF02938 GAD domain 305 397 5.1E-14 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 SUPERFAMILY SSF55261 286 415 4.58E-31 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 574 1.6E-216 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 579 32.079 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 Gene3D G3DSA:2.40.50.140 1 101 2.1E-32 T 12-10-2018 AFR_30805 db672bde334d6badf6c3bd8a4ff009fd 600 Pfam PF00152 tRNA synthetases class II (D, K and N) 115 552 7.4E-101 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_26800 d7dd1503dd6a5100462a88aebaeda482 246 Gene3D G3DSA:3.30.750.24 2 112 4.5E-11 T 12-10-2018 IPR036513 STAS domain superfamily AFR_26800 d7dd1503dd6a5100462a88aebaeda482 246 SUPERFAMILY SSF52091 5 108 9.22E-9 T 12-10-2018 IPR036513 STAS domain superfamily AFR_26800 d7dd1503dd6a5100462a88aebaeda482 246 Pfam PF13581 Histidine kinase-like ATPase domain 133 237 1.5E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_26800 d7dd1503dd6a5100462a88aebaeda482 246 SUPERFAMILY SSF55874 153 232 6.35E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26800 d7dd1503dd6a5100462a88aebaeda482 246 Pfam PF13466 STAS domain 17 90 7.0E-7 T 12-10-2018 IPR002645 STAS domain AFR_26800 d7dd1503dd6a5100462a88aebaeda482 246 Gene3D G3DSA:3.30.565.10 128 244 1.7E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12660 19060f0b8a8c65abef14c9de70e04538 421 SUPERFAMILY SSF50998 159 351 4.45E-19 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_12660 19060f0b8a8c65abef14c9de70e04538 421 Pfam PF13360 PQQ-like domain 84 264 4.4E-12 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_12660 19060f0b8a8c65abef14c9de70e04538 421 SUPERFAMILY SSF50998 66 177 1.31E-8 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_12660 19060f0b8a8c65abef14c9de70e04538 421 Gene3D G3DSA:2.130.10.10 24 225 2.5E-16 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_12660 19060f0b8a8c65abef14c9de70e04538 421 Gene3D G3DSA:2.130.10.10 226 421 2.4E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Pfam PF02983 Alpha-lytic protease prodomain 125 182 5.4E-17 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 SUPERFAMILY SSF50494 206 376 5.98E-33 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Gene3D G3DSA:3.30.300.50 42 123 3.1E-15 T 12-10-2018 IPR035070 Streptogrisin prodomain AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Gene3D G3DSA:2.80.10.50 380 432 1.0E-8 T 12-10-2018 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Pfam PF00652 Ricin-type beta-trefoil lectin domain 393 512 2.2E-20 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Gene3D G3DSA:2.40.10.10 202 379 3.6E-71 T 12-10-2018 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 SUPERFAMILY SSF50370 388 513 1.37E-30 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 SMART SM00458 388 515 2.7E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Gene3D G3DSA:3.30.300.50 125 191 1.1E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Gene3D G3DSA:2.40.10.10 271 369 3.6E-71 T 12-10-2018 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 303 7.6E-39 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 347 361 7.6E-39 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 346 7.6E-39 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 304 321 7.6E-39 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 223 237 7.6E-39 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_33250 be6dd0fd076edcc7cc124e9c27750b4c 515 Gene3D G3DSA:2.80.10.50 433 515 3.1E-20 T 12-10-2018 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 PIRSF PIRSF000157 2 1246 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Gene3D G3DSA:3.40.50.12470 861 1117 3.0E-160 T 12-10-2018 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Pfam PF02779 Transketolase, pyrimidine binding domain 902 1096 3.0E-55 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Gene3D G3DSA:1.10.287.1150 396 477 2.0E-27 T 12-10-2018 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 132 364 4.4E-50 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 15 48 1.1E-10 T 12-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 SMART SM00861 902 1095 1.4E-47 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Gene3D G3DSA:3.30.559.10 114 372 8.8E-52 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 SUPERFAMILY SSF52518 432 837 4.95E-86 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 398 1243 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Gene3D G3DSA:3.40.50.11610 1038 1242 3.0E-160 T 12-10-2018 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1100 1244 3.1E-47 T 12-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Gene3D G3DSA:3.40.50.970 478 842 4.4E-147 T 12-10-2018 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 SUPERFAMILY SSF52777 119 364 1.96E-53 T 12-10-2018 AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 SUPERFAMILY SSF52518 889 1101 1.37E-43 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_37970 b68a62cbe03df4d10326da8477ec7014 1247 Pfam PF00676 Dehydrogenase E1 component 518 837 1.8E-55 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 Gene3D G3DSA:1.25.40.10 19 107 1.1E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 Pfam PF12770 CHAT domain 662 841 2.4E-20 T 12-10-2018 IPR024983 CHAT domain AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 SMART SM00028 115 148 47.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 SMART SM00028 273 306 69.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 SMART SM00028 195 228 0.44 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 SMART SM00028 39 72 270.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 SMART SM00028 155 188 1.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 Gene3D G3DSA:1.25.40.10 108 425 1.3E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 SUPERFAMILY SSF48452 195 309 3.67E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 Pfam PF13424 Tetratricopeptide repeat 153 224 1.8E-9 T 12-10-2018 AFR_08345 99d64ea7bae9c0e58c60108a4f56bbea 864 SUPERFAMILY SSF48452 23 222 1.06E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00555 a12f050fb4e393a9ed3e28e28a20c832 404 SUPERFAMILY SSF103473 18 400 1.44E-45 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_00555 a12f050fb4e393a9ed3e28e28a20c832 404 Pfam PF07690 Major Facilitator Superfamily 25 301 7.0E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_00555 a12f050fb4e393a9ed3e28e28a20c832 404 Gene3D G3DSA:1.20.1250.20 13 221 1.8E-19 T 12-10-2018 AFR_00555 a12f050fb4e393a9ed3e28e28a20c832 404 Gene3D G3DSA:1.20.1250.20 222 403 7.2E-18 T 12-10-2018 AFR_41420 9734c298d130e352fb37e970ac0c77f7 333 Gene3D G3DSA:3.40.190.10 46 123 1.3E-7 T 12-10-2018 AFR_41420 9734c298d130e352fb37e970ac0c77f7 333 SUPERFAMILY SSF53850 133 331 2.17E-22 T 12-10-2018 AFR_41420 9734c298d130e352fb37e970ac0c77f7 333 SUPERFAMILY SSF53850 49 121 3.22E-9 T 12-10-2018 AFR_41420 9734c298d130e352fb37e970ac0c77f7 333 Gene3D G3DSA:3.40.190.10 130 270 1.5E-16 T 12-10-2018 AFR_41420 9734c298d130e352fb37e970ac0c77f7 333 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 133 331 2.4E-27 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 AFR_41420 9734c298d130e352fb37e970ac0c77f7 333 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 49 117 5.3E-10 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 Gene3D G3DSA:3.30.9.30 37 260 7.6E-73 T 12-10-2018 AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 Gene3D G3DSA:3.50.50.60 6 333 7.6E-73 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 2.6E-19 T 12-10-2018 AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 2.6E-19 T 12-10-2018 AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.6E-19 T 12-10-2018 AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 2.6E-19 T 12-10-2018 AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 Pfam PF01494 FAD binding domain 4 330 4.7E-23 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_06280 eda3770d610b7372e3f6c3bf6fda9d61 369 SUPERFAMILY SSF51905 4 337 3.18E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_11540 38f96a559c3aaf5d9feca89435987d9d 229 Gene3D G3DSA:3.40.50.300 1 228 2.6E-64 T 12-10-2018 AFR_11540 38f96a559c3aaf5d9feca89435987d9d 229 Pfam PF00005 ABC transporter 24 174 3.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_11540 38f96a559c3aaf5d9feca89435987d9d 229 SUPERFAMILY SSF52540 4 225 1.86E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11540 38f96a559c3aaf5d9feca89435987d9d 229 SMART SM00382 33 224 6.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_11540 38f96a559c3aaf5d9feca89435987d9d 229 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_33560 c1d1468f840fdcf4229a2dd62976f0d2 166 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 2 108 2.7E-8 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_33560 c1d1468f840fdcf4229a2dd62976f0d2 166 SUPERFAMILY SSF109854 1 114 2.38E-12 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_33560 c1d1468f840fdcf4229a2dd62976f0d2 166 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 1 160 1.5E-30 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 AFR_33560 c1d1468f840fdcf4229a2dd62976f0d2 166 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 2 145 2.5E-21 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_04170 e045a483a58372ec66a14ce04f180ff7 266 Gene3D G3DSA:3.40.50.150 2 260 6.8E-53 T 12-10-2018 AFR_04170 e045a483a58372ec66a14ce04f180ff7 266 Pfam PF04072 Leucine carboxyl methyltransferase 12 170 1.8E-37 T 12-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 AFR_04170 e045a483a58372ec66a14ce04f180ff7 266 SUPERFAMILY SSF53335 6 254 1.1E-52 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_04170 e045a483a58372ec66a14ce04f180ff7 266 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 246 2.4E-49 T 12-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 AFR_01920 4093499a0cadf087660f4412f87222f0 401 Gene3D G3DSA:3.20.20.10 29 273 1.6E-48 T 12-10-2018 IPR029066 PLP-binding barrel AFR_01920 4093499a0cadf087660f4412f87222f0 401 SUPERFAMILY SSF51419 27 278 6.05E-18 T 12-10-2018 IPR029066 PLP-binding barrel AFR_01920 4093499a0cadf087660f4412f87222f0 401 Pfam PF01168 Alanine racemase, N-terminal domain 26 275 6.5E-13 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_33475 77271684cd6e7ef66b9dacb0818db968 73 Gene3D G3DSA:3.30.70.20 3 69 9.7E-13 T 12-10-2018 AFR_33475 77271684cd6e7ef66b9dacb0818db968 73 SUPERFAMILY SSF54862 5 68 1.12E-6 T 12-10-2018 AFR_33475 77271684cd6e7ef66b9dacb0818db968 73 Pfam PF13459 4Fe-4S single cluster domain 7 67 5.3E-13 T 12-10-2018 AFR_41065 35f517a1511282bb85296816d41cce33 1069 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 177 188 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_41065 35f517a1511282bb85296816d41cce33 1069 SUPERFAMILY SSF52743 165 618 1.76E-50 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_41065 35f517a1511282bb85296816d41cce33 1069 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 552 562 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_41065 35f517a1511282bb85296816d41cce33 1069 Gene3D G3DSA:3.40.50.200 156 242 1.7E-7 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_41065 35f517a1511282bb85296816d41cce33 1069 Gene3D G3DSA:3.40.50.200 307 623 3.8E-62 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_41065 35f517a1511282bb85296816d41cce33 1069 Gene3D G3DSA:2.60.120.380 912 1002 9.7E-6 T 12-10-2018 AFR_41065 35f517a1511282bb85296816d41cce33 1069 PRINTS PR00723 Subtilisin serine protease family (S8) signature 551 567 2.3E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41065 35f517a1511282bb85296816d41cce33 1069 PRINTS PR00723 Subtilisin serine protease family (S8) signature 172 191 2.3E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41065 35f517a1511282bb85296816d41cce33 1069 PRINTS PR00723 Subtilisin serine protease family (S8) signature 353 366 2.3E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41065 35f517a1511282bb85296816d41cce33 1069 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 922 986 1.3E-7 T 12-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial AFR_41065 35f517a1511282bb85296816d41cce33 1069 Pfam PF00082 Subtilase family 172 605 2.8E-55 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 SUPERFAMILY SSF51445 162 421 2.6E-19 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 Pfam PF00704 Glycosyl hydrolases family 18 168 359 4.5E-9 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 SUPERFAMILY SSF50370 18 140 4.95E-38 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 Gene3D G3DSA:3.20.20.80 159 450 5.3E-80 T 12-10-2018 AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 Gene3D G3DSA:2.80.10.50 109 157 2.7E-11 T 12-10-2018 AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 Pfam PF00652 Ricin-type beta-trefoil lectin domain 18 139 9.5E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 Gene3D G3DSA:2.80.10.50 12 108 3.5E-28 T 12-10-2018 AFR_42305 9dfd3ea00ea3f38b6a59c2dfdbd7f78b 450 SMART SM00458 18 142 2.0E-26 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_42920 4969a51fbcc62e6b98c47aa9a19cab79 243 SUPERFAMILY SSF88659 134 193 2.62E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_42920 4969a51fbcc62e6b98c47aa9a19cab79 243 Gene3D G3DSA:1.10.1740.10 15 121 1.2E-29 T 12-10-2018 AFR_42920 4969a51fbcc62e6b98c47aa9a19cab79 243 Pfam PF04542 Sigma-70 region 2 39 105 1.6E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_42920 4969a51fbcc62e6b98c47aa9a19cab79 243 Gene3D G3DSA:1.10.10.10 136 196 1.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42920 4969a51fbcc62e6b98c47aa9a19cab79 243 SUPERFAMILY SSF88946 16 114 5.81E-29 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_42920 4969a51fbcc62e6b98c47aa9a19cab79 243 Pfam PF08281 Sigma-70, region 4 141 191 1.0E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_42920 4969a51fbcc62e6b98c47aa9a19cab79 243 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 193 4.3E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 SMART SM00228 301 378 1.8E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 Gene3D G3DSA:2.40.10.10 83 178 2.3E-26 T 12-10-2018 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 4.0E-47 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 PRINTS PR00834 HtrA/DegQ protease family signature 336 348 4.0E-47 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 4.0E-47 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 PRINTS PR00834 HtrA/DegQ protease family signature 148 168 4.0E-47 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 PRINTS PR00834 HtrA/DegQ protease family signature 228 245 4.0E-47 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 PRINTS PR00834 HtrA/DegQ protease family signature 250 267 4.0E-47 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 SUPERFAMILY SSF50156 282 387 3.02E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 Gene3D G3DSA:2.40.10.10 179 298 1.6E-41 T 12-10-2018 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 Gene3D G3DSA:2.30.42.10 300 392 3.0E-18 T 12-10-2018 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 Pfam PF13365 Trypsin-like peptidase domain 117 257 2.8E-32 T 12-10-2018 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 Pfam PF13180 PDZ domain 317 387 2.2E-15 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_40065 9b7c7b0f83034f5a85a70d37b686f8c8 392 SUPERFAMILY SSF50494 93 293 4.47E-54 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 Gene3D G3DSA:3.40.220.10 7 172 7.0E-30 T 12-10-2018 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 SUPERFAMILY SSF52949 20 172 2.12E-24 T 12-10-2018 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 8 514 31.608 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 196 505 1.4E-110 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 24 157 1.6E-22 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 358 365 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 SUPERFAMILY SSF53187 191 511 3.77E-102 T 12-10-2018 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 PRINTS PR00481 Cytosol aminopeptidase signature 382 397 7.9E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 PRINTS PR00481 Cytosol aminopeptidase signature 273 290 7.9E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 PRINTS PR00481 Cytosol aminopeptidase signature 332 353 7.9E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 PRINTS PR00481 Cytosol aminopeptidase signature 295 316 7.9E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 PRINTS PR00481 Cytosol aminopeptidase signature 354 374 7.9E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFR_09270 791e0aef227fc858906ba8a5e3b6a7e0 516 Gene3D G3DSA:3.40.630.10 176 515 1.2E-120 T 12-10-2018 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 SMART SM00283 274 528 2.5E-54 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 178 1.2E-17 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_01980 0bb7c720014baf96cdd045f380a23440 529 Gene3D G3DSA:1.10.287.950 214 529 3.0E-65 T 12-10-2018 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 SMART SM00304 214 266 0.0011 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 495 1.5E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 SUPERFAMILY SSF58104 234 527 1.44E-64 T 12-10-2018 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 295 324 1.8E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 430 1.8E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 449 478 1.8E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_01980 0bb7c720014baf96cdd045f380a23440 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 372 399 1.8E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_15690 2eb4756807c3cdc891310ea30e8cf72e 351 Pfam PF13416 Bacterial extracellular solute-binding protein 55 305 4.8E-23 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_15690 2eb4756807c3cdc891310ea30e8cf72e 351 Gene3D G3DSA:3.40.190.10 40 348 8.7E-88 T 12-10-2018 AFR_15690 2eb4756807c3cdc891310ea30e8cf72e 351 Gene3D G3DSA:3.40.190.10 134 256 8.7E-88 T 12-10-2018 AFR_15690 2eb4756807c3cdc891310ea30e8cf72e 351 SUPERFAMILY SSF53850 33 351 9.83E-42 T 12-10-2018 AFR_32640 a83d3345c66e94d28592beb179a5ad62 704 Gene3D G3DSA:2.60.40.10 626 702 8.5E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_32640 a83d3345c66e94d28592beb179a5ad62 704 SUPERFAMILY SSF48452 8 114 3.16E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32640 a83d3345c66e94d28592beb179a5ad62 704 Gene3D G3DSA:1.25.40.10 4 207 1.9E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32640 a83d3345c66e94d28592beb179a5ad62 704 SUPERFAMILY SSF49265 618 696 1.89E-6 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_18470 db34fd29d2941556d15df7326bd8fcec 317 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 306 1.1E-95 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFR_18470 db34fd29d2941556d15df7326bd8fcec 317 Pfam PF00005 ABC transporter 21 164 4.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18470 db34fd29d2941556d15df7326bd8fcec 317 SUPERFAMILY SSF52540 11 228 4.87E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18470 db34fd29d2941556d15df7326bd8fcec 317 Gene3D G3DSA:3.40.50.300 3 238 9.6E-63 T 12-10-2018 AFR_18470 db34fd29d2941556d15df7326bd8fcec 317 Pfam PF13732 Domain of unknown function (DUF4162) 218 308 6.8E-7 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 AFR_18470 db34fd29d2941556d15df7326bd8fcec 317 SMART SM00382 30 212 5.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_19285 0b1af8900a4831c66a601729d5c27acc 252 SMART SM00882 7 217 3.1E-29 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFR_19285 0b1af8900a4831c66a601729d5c27acc 252 SUPERFAMILY SSF100950 1 245 3.14E-67 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_19285 0b1af8900a4831c66a601729d5c27acc 252 Gene3D G3DSA:3.40.1080.10 1 248 1.3E-78 T 12-10-2018 AFR_19285 0b1af8900a4831c66a601729d5c27acc 252 Pfam PF01144 Coenzyme A transferase 7 216 1.1E-35 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFR_14935 662ac30b65eb32d1c37fba3cbf248308 535 Gene3D G3DSA:3.30.200.20 8 102 1.7E-30 T 12-10-2018 AFR_14935 662ac30b65eb32d1c37fba3cbf248308 535 Gene3D G3DSA:1.10.510.10 104 288 6.6E-44 T 12-10-2018 AFR_14935 662ac30b65eb32d1c37fba3cbf248308 535 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_14935 662ac30b65eb32d1c37fba3cbf248308 535 Pfam PF00069 Protein kinase domain 19 273 8.6E-47 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_14935 662ac30b65eb32d1c37fba3cbf248308 535 SUPERFAMILY SSF56112 16 282 1.75E-67 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_14935 662ac30b65eb32d1c37fba3cbf248308 535 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 48 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_14935 662ac30b65eb32d1c37fba3cbf248308 535 SMART SM00220 19 281 1.1E-56 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_25830 7c229a979cb959db56c6cce3878dec67 191 Pfam PF13302 Acetyltransferase (GNAT) domain 12 154 3.7E-28 T 12-10-2018 IPR000182 GNAT domain AFR_25830 7c229a979cb959db56c6cce3878dec67 191 Gene3D G3DSA:3.40.630.30 5 189 7.6E-51 T 12-10-2018 AFR_25830 7c229a979cb959db56c6cce3878dec67 191 SUPERFAMILY SSF55729 7 178 1.95E-46 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 Gene3D G3DSA:1.10.150.240 15 97 7.4E-72 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 SUPERFAMILY SSF56784 2 209 4.28E-33 T 12-10-2018 IPR036412 HAD-like superfamily AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 5.6E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 5.6E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 5.6E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 130 197 4.2E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 197 3.9E-15 T 12-10-2018 AFR_23225 d1da878af9eb09bff87435cab1d8b35c 255 Gene3D G3DSA:3.40.50.1000 3 216 7.4E-72 T 12-10-2018 IPR023214 HAD superfamily AFR_39365 66b6f0c21db715380a1ce320b4b9e22d 186 Hamap MF_00528 Septum formation protein Maf [maf]. 1 178 22.138 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFR_39365 66b6f0c21db715380a1ce320b4b9e22d 186 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 171 1.7E-45 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFR_39365 66b6f0c21db715380a1ce320b4b9e22d 186 Pfam PF02545 Maf-like protein 1 172 6.3E-41 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFR_39365 66b6f0c21db715380a1ce320b4b9e22d 186 PIRSF PIRSF006305 1 178 2.4E-39 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFR_39365 66b6f0c21db715380a1ce320b4b9e22d 186 Gene3D G3DSA:3.90.950.10 1 178 2.6E-55 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFR_39365 66b6f0c21db715380a1ce320b4b9e22d 186 SUPERFAMILY SSF52972 1 172 1.31E-48 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFR_19730 77fd7674a47128d81141eb8cf71f9f97 267 Gene3D G3DSA:3.40.50.150 10 142 1.0E-12 T 12-10-2018 AFR_19730 77fd7674a47128d81141eb8cf71f9f97 267 Pfam PF13649 Methyltransferase domain 41 133 2.9E-8 T 12-10-2018 AFR_19730 77fd7674a47128d81141eb8cf71f9f97 267 SUPERFAMILY SSF53335 25 133 1.53E-12 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_33530 f4dbccbea69fa7c465cc3987bd9529f0 255 Pfam PF01061 ABC-2 type transporter 32 223 4.9E-13 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_33530 f4dbccbea69fa7c465cc3987bd9529f0 255 PIRSF PIRSF006648 2 253 2.7E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_01880 ac5f104c9ecae2fcf8585f136a7da12d 123 Pfam PF01740 STAS domain 7 108 3.0E-17 T 12-10-2018 IPR002645 STAS domain AFR_01880 ac5f104c9ecae2fcf8585f136a7da12d 123 SUPERFAMILY SSF52091 3 110 1.0E-28 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01880 ac5f104c9ecae2fcf8585f136a7da12d 123 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 3.6E-28 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_01880 ac5f104c9ecae2fcf8585f136a7da12d 123 Gene3D G3DSA:3.30.750.24 1 113 1.3E-34 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01620 7ca581a2eaf3a3b6ae2b24f257376364 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 119 3.1E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_01620 7ca581a2eaf3a3b6ae2b24f257376364 126 SUPERFAMILY SSF54593 7 122 8.99E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_01620 7ca581a2eaf3a3b6ae2b24f257376364 126 Gene3D G3DSA:3.10.180.10 2 126 1.1E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 Gene3D G3DSA:1.10.10.10 124 222 1.3E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 Gene3D G3DSA:3.40.50.2300 1 123 2.7E-33 T 12-10-2018 AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 SMART SM00862 145 220 5.2E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 1.7E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 Pfam PF00072 Response regulator receiver domain 1 109 6.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 SMART SM00448 1 109 6.6E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 SUPERFAMILY SSF46894 126 220 2.15E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_19235 6bacf03aa3f02ea990938623f2f988cd 222 SUPERFAMILY SSF52172 1 121 1.71E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_09260 dd3275176f2200e3376dc718f419b857 461 SUPERFAMILY SSF51905 7 364 9.26E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09260 dd3275176f2200e3376dc718f419b857 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 320 6.4E-67 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_09260 dd3275176f2200e3376dc718f419b857 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 448 6.6E-26 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_09260 dd3275176f2200e3376dc718f419b857 461 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 8 458 1.2E-141 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFR_09260 dd3275176f2200e3376dc718f419b857 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFR_09260 dd3275176f2200e3376dc718f419b857 461 Gene3D G3DSA:3.50.50.60 146 264 1.1E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09260 dd3275176f2200e3376dc718f419b857 461 SUPERFAMILY SSF55424 339 458 1.89E-30 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 2.1E-35 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 2.1E-35 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 2.1E-35 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 2.1E-35 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.1E-35 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 Gene3D G3DSA:3.50.50.60 8 322 1.1E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 4.5E-67 T 12-10-2018 AFR_09260 dd3275176f2200e3376dc718f419b857 461 PIRSF PIRSF000350 1 445 5.1E-75 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_09260 dd3275176f2200e3376dc718f419b857 461 Gene3D G3DSA:3.30.390.30 339 459 4.8E-33 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 388 6.0E-135 T 12-10-2018 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 390 133.043 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 Gene3D G3DSA:3.30.2330.10 186 264 1.5E-25 T 12-10-2018 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 Pfam PF01960 ArgJ family 11 390 1.5E-127 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 SUPERFAMILY SSF56266 6 386 4.05E-125 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 Gene3D G3DSA:3.10.20.340 265 390 4.3E-42 T 12-10-2018 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 Gene3D G3DSA:3.60.70.12 1 185 2.0E-59 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFR_30240 76a49b4604514bf2c71787e751014b0b 390 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 389 2.5E-104 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFR_24765 6189f874b1f01fd5f8e087b37808d9bf 454 SUPERFAMILY SSF53474 70 415 1.93E-18 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 Pfam PF01327 Polypeptide deformylase 341 494 9.0E-30 T 12-10-2018 IPR023635 Peptide deformylase AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 Hamap MF_00163 Peptide deformylase [def]. 335 507 20.539 T 12-10-2018 IPR023635 Peptide deformylase AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 SUPERFAMILY SSF56420 334 503 1.57E-34 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 SMART SM00530 16 71 2.6E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 Gene3D G3DSA:1.10.260.40 5 86 7.9E-9 T 12-10-2018 AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 Pfam PF13560 Helix-turn-helix domain 15 69 6.2E-8 T 12-10-2018 AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 Gene3D G3DSA:3.90.45.10 328 507 8.2E-36 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 SUPERFAMILY SSF47413 17 84 3.66E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 PRINTS PR01576 Peptide deformylase signature 465 494 2.5E-17 T 12-10-2018 IPR023635 Peptide deformylase AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 PRINTS PR01576 Peptide deformylase signature 377 406 2.5E-17 T 12-10-2018 IPR023635 Peptide deformylase AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 PRINTS PR01576 Peptide deformylase signature 434 445 2.5E-17 T 12-10-2018 IPR023635 Peptide deformylase AFR_42190 cbc00b056daaacb071e9b0a232090e97 513 PRINTS PR01576 Peptide deformylase signature 446 464 2.5E-17 T 12-10-2018 IPR023635 Peptide deformylase AFR_29875 edd804bf0cdb48204bf34d53d5d0d944 303 SUPERFAMILY SSF56349 4 294 4.12E-56 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_29875 edd804bf0cdb48204bf34d53d5d0d944 303 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 2 302 52.877 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFR_29875 edd804bf0cdb48204bf34d53d5d0d944 303 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 4 302 52.736 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD AFR_29875 edd804bf0cdb48204bf34d53d5d0d944 303 Gene3D G3DSA:1.10.150.130 3 103 2.4E-18 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_29875 edd804bf0cdb48204bf34d53d5d0d944 303 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 94 2.3E-19 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFR_29875 edd804bf0cdb48204bf34d53d5d0d944 303 Pfam PF00589 Phage integrase family 116 286 1.9E-44 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_29875 edd804bf0cdb48204bf34d53d5d0d944 303 Gene3D G3DSA:1.10.443.10 115 296 3.0E-58 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_13750 bb1ad6dd58bad0cae8eaa601721a8481 532 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 8 522 3.0E-112 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 AFR_13750 bb1ad6dd58bad0cae8eaa601721a8481 532 Pfam PF00999 Sodium/hydrogen exchanger family 8 403 2.0E-52 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_18450 544f6c6fbc0836ec7ee838d2246a244d 344 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_18450 544f6c6fbc0836ec7ee838d2246a244d 344 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 331 6.0E-105 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 AFR_18450 544f6c6fbc0836ec7ee838d2246a244d 344 Gene3D G3DSA:3.40.50.300 28 307 8.6E-83 T 12-10-2018 AFR_18450 544f6c6fbc0836ec7ee838d2246a244d 344 SUPERFAMILY SSF52540 39 269 1.4E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18450 544f6c6fbc0836ec7ee838d2246a244d 344 SMART SM00382 53 250 2.8E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18450 544f6c6fbc0836ec7ee838d2246a244d 344 Pfam PF00005 ABC transporter 44 192 7.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 SUPERFAMILY SSF51735 3 250 1.96E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 Gene3D G3DSA:3.40.50.720 3 251 1.3E-86 T 12-10-2018 AFR_03185 e72cab34e78898c15ee495fd6a37ba38 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 249 6.9E-61 T 12-10-2018 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 6.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 6.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 6.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 Pfam PF00072 Response regulator receiver domain 5 113 3.4E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 SMART SM00421 158 215 3.2E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 SUPERFAMILY SSF46894 146 215 6.46E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 SMART SM00448 2 113 8.8E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 SUPERFAMILY SSF52172 1 131 3.98E-24 T 12-10-2018 IPR011006 CheY-like superfamily AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 213 2.9E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38370 99f95ad49ca5ac8bf10fe1c23987cef9 217 Gene3D G3DSA:3.40.50.12740 2 216 2.5E-53 T 12-10-2018 AFR_11930 ee8ef3363c33307918b730daa6e61c61 144 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 3 129 1.7E-20 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 AFR_11930 ee8ef3363c33307918b730daa6e61c61 144 SUPERFAMILY SSF54427 2 133 4.3E-29 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_11930 ee8ef3363c33307918b730daa6e61c61 144 Pfam PF14534 Domain of unknown function (DUF4440) 11 121 8.3E-10 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 AFR_11930 ee8ef3363c33307918b730daa6e61c61 144 Gene3D G3DSA:3.10.450.50 2 139 1.6E-35 T 12-10-2018 AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 PIRSF PIRSF016578 1 347 3.4E-71 T 12-10-2018 AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 79 1.9E-5 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 207 333 5.5E-21 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 SUPERFAMILY SSF47203 197 336 1.21E-12 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 Gene3D G3DSA:2.40.110.10 99 186 1.1E-20 T 12-10-2018 AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 SUPERFAMILY SSF56645 5 185 5.37E-23 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 Gene3D G3DSA:1.10.540.10 1 98 4.6E-18 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_14585 c37bc743ba28b895a0647dfefe4b4404 347 Gene3D G3DSA:1.20.140.10 195 347 1.1E-28 T 12-10-2018 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 Gene3D G3DSA:3.40.50.12740 1 203 2.9E-45 T 12-10-2018 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 Pfam PF00072 Response regulator receiver domain 1 109 1.6E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 SUPERFAMILY SSF46894 130 202 2.18E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 SUPERFAMILY SSF52172 1 123 1.57E-22 T 12-10-2018 IPR011006 CheY-like superfamily AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 SMART SM00448 1 112 9.1E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 1.7E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 1.7E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 1.7E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 SMART SM00421 140 197 6.7E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_22020 3a6575c5dae163fa1c1bcc51ec88b19a 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 197 5.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24880 caaae11bc495e0c1f8c4424c9a4e43c0 120 Gene3D G3DSA:1.10.10.10 4 120 8.5E-40 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24880 caaae11bc495e0c1f8c4424c9a4e43c0 120 SUPERFAMILY SSF46785 9 116 5.2E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24880 caaae11bc495e0c1f8c4424c9a4e43c0 120 Pfam PF01638 HxlR-like helix-turn-helix 22 110 4.3E-26 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_13635 a27004f798e3d41c79a57cb7d8481969 296 Gene3D G3DSA:3.30.450.180 111 282 1.8E-13 T 12-10-2018 AFR_13635 a27004f798e3d41c79a57cb7d8481969 296 SUPERFAMILY SSF47413 32 80 4.3E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_13635 a27004f798e3d41c79a57cb7d8481969 296 Gene3D G3DSA:1.10.260.40 28 104 1.2E-5 T 12-10-2018 AFR_13635 a27004f798e3d41c79a57cb7d8481969 296 SMART SM00530 10 83 0.0012 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_13635 a27004f798e3d41c79a57cb7d8481969 296 Pfam PF13560 Helix-turn-helix domain 10 86 7.7E-15 T 12-10-2018 AFR_25405 a66d80b82e16764c30d783483914eb2f 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 269 1.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_25405 a66d80b82e16764c30d783483914eb2f 285 Gene3D G3DSA:1.10.3720.10 36 279 3.5E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_25405 a66d80b82e16764c30d783483914eb2f 285 SUPERFAMILY SSF161098 41 268 4.84E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Pfam PF04898 Glutamate synthase central domain 450 738 1.2E-112 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Pfam PF01645 Conserved region in glutamate synthase 802 1165 1.0E-151 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Pfam PF00310 Glutamine amidotransferases class-II 1 424 1.6E-170 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 SUPERFAMILY SSF51395 438 1201 2.28E-260 T 12-10-2018 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Gene3D G3DSA:3.20.20.70 433 787 2.3E-133 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 SUPERFAMILY SSF69336 1214 1476 1.57E-88 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Gene3D G3DSA:3.60.20.10 1 432 6.4E-170 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Gene3D G3DSA:2.160.20.60 1217 1484 1.4E-105 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Gene3D G3DSA:3.20.20.70 788 1210 1.1E-185 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 Pfam PF01493 GXGXG motif 1245 1429 3.3E-76 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AFR_10335 dbcb0ecc03f06ffacc46e7fb0c9fb7f9 1496 SUPERFAMILY SSF56235 1 426 1.0E-141 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_12910 8bdbc7992515daa65153723761e78640 473 PIRSF PIRSF000350 1 470 1.4E-76 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 3.8E-21 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.8E-21 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.8E-21 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 3.8E-21 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 Gene3D G3DSA:3.30.390.30 356 472 2.4E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_12910 8bdbc7992515daa65153723761e78640 473 Gene3D G3DSA:3.50.50.60 157 275 1.8E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_12910 8bdbc7992515daa65153723761e78640 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 318 5.7E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_12910 8bdbc7992515daa65153723761e78640 473 Gene3D G3DSA:3.50.50.60 6 330 1.8E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_12910 8bdbc7992515daa65153723761e78640 473 SUPERFAMILY SSF55424 354 470 2.75E-29 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_12910 8bdbc7992515daa65153723761e78640 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 358 463 9.5E-23 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 462 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 354 375 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 435 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 4.4E-53 T 12-10-2018 AFR_12910 8bdbc7992515daa65153723761e78640 473 SUPERFAMILY SSF51905 2 335 6.76E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23965 e254e382e08a0a2a37ede90295b0d2a0 454 Pfam PF01547 Bacterial extracellular solute-binding protein 76 339 2.2E-15 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_23965 e254e382e08a0a2a37ede90295b0d2a0 454 Gene3D G3DSA:3.40.190.10 172 433 3.2E-41 T 12-10-2018 AFR_23965 e254e382e08a0a2a37ede90295b0d2a0 454 Gene3D G3DSA:3.40.190.10 87 400 3.2E-41 T 12-10-2018 AFR_23965 e254e382e08a0a2a37ede90295b0d2a0 454 SUPERFAMILY SSF53850 58 452 3.51E-40 T 12-10-2018 AFR_35295 a7d9b4a2b4232d9f4a3db31d6ff78a5e 170 Gene3D G3DSA:2.70.40.10 8 162 3.0E-51 T 12-10-2018 IPR036157 dUTPase-like superfamily AFR_35295 a7d9b4a2b4232d9f4a3db31d6ff78a5e 170 SUPERFAMILY SSF51283 17 158 1.7E-46 T 12-10-2018 IPR036157 dUTPase-like superfamily AFR_35295 a7d9b4a2b4232d9f4a3db31d6ff78a5e 170 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 17 159 30.719 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 AFR_35295 a7d9b4a2b4232d9f4a3db31d6ff78a5e 170 TIGRFAM TIGR00576 dut: dUTP diphosphatase 20 158 1.2E-50 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 AFR_35295 a7d9b4a2b4232d9f4a3db31d6ff78a5e 170 Pfam PF00692 dUTPase 29 158 3.0E-29 T 12-10-2018 IPR029054 dUTPase-like AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 122 134 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 SUPERFAMILY SSF55724 500 628 6.8E-5 T 12-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 Pfam PF01789 PsbP 498 628 2.1E-6 T 12-10-2018 IPR002683 PsbP family GO:0005509|GO:0009523|GO:0009654|GO:0015979|GO:0019898 AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 Gene3D G3DSA:3.30.200.20 1 82 7.7E-25 T 12-10-2018 AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 5 28 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 Pfam PF00069 Protein kinase domain 4 246 6.5E-41 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 SUPERFAMILY SSF56112 5 298 3.91E-63 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 SMART SM00220 1 257 4.9E-50 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 Gene3D G3DSA:1.10.510.10 83 271 5.6E-39 T 12-10-2018 AFR_39465 2f311f5ed736b39431ce5e80e89a18da 632 Gene3D G3DSA:3.40.1000.10 494 632 3.1E-7 T 12-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich AFR_30585 412d87d6c7a6db7e3322fe937cfd4fc6 87 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 10 79 3.5E-23 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_30585 412d87d6c7a6db7e3322fe937cfd4fc6 87 Pfam PF01192 RNA polymerase Rpb6 17 79 3.7E-13 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFR_30585 412d87d6c7a6db7e3322fe937cfd4fc6 87 SMART SM01409 17 81 1.9E-13 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFR_30585 412d87d6c7a6db7e3322fe937cfd4fc6 87 SUPERFAMILY SSF63562 10 85 3.49E-24 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFR_30585 412d87d6c7a6db7e3322fe937cfd4fc6 87 Gene3D G3DSA:3.90.940.10 10 87 1.4E-20 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFR_30585 412d87d6c7a6db7e3322fe937cfd4fc6 87 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 10 82 14.882 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFR_38250 3ae51df6ba1f78592fdb798831154bb4 285 Pfam PF01564 Spermine/spermidine synthase domain 71 180 6.2E-7 T 12-10-2018 AFR_38250 3ae51df6ba1f78592fdb798831154bb4 285 SUPERFAMILY SSF53335 7 236 3.79E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_38250 3ae51df6ba1f78592fdb798831154bb4 285 Gene3D G3DSA:3.40.50.150 9 269 1.6E-72 T 12-10-2018 AFR_05670 1e59771912592907da2fa60c1fdb41ad 121 Pfam PF06262 Zincin-like metallopeptidase 34 120 2.8E-13 T 12-10-2018 IPR010428 Zincin-like metallopeptidase AFR_05670 1e59771912592907da2fa60c1fdb41ad 121 SUPERFAMILY SSF55486 9 120 3.66E-28 T 12-10-2018 AFR_05670 1e59771912592907da2fa60c1fdb41ad 121 Gene3D G3DSA:3.30.2010.20 7 121 6.2E-14 T 12-10-2018 IPR038555 Zincin-like metallopeptidase superfamily AFR_32350 e457f1a2b6a20b3b1a8b2519c006273f 96 Pfam PF07561 Domain of Unknown Function (DUF1540) 61 93 3.8E-4 T 12-10-2018 IPR011437 Domain of unknown function DUF1540 AFR_32350 e457f1a2b6a20b3b1a8b2519c006273f 96 Pfam PF07561 Domain of Unknown Function (DUF1540) 13 42 0.0013 T 12-10-2018 IPR011437 Domain of unknown function DUF1540 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 3.4E-47 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 3.4E-47 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 3.4E-47 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 3.4E-47 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 3.4E-47 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 Pfam PF00574 Clp protease 23 196 9.8E-77 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 8 198 39.694 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 Gene3D G3DSA:3.90.226.10 7 199 1.9E-73 T 12-10-2018 AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 12-10-2018 IPR033135 ClpP, histidine active site AFR_07540 53ae9b1e5977e3956caefbe2ac19e263 209 SUPERFAMILY SSF52096 24 196 5.8E-67 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_22660 3509bfd291fda8189e2a9b1ac0f7031d 280 Pfam PF01261 Xylose isomerase-like TIM barrel 22 232 1.2E-27 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_22660 3509bfd291fda8189e2a9b1ac0f7031d 280 SUPERFAMILY SSF51658 4 274 7.46E-50 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_22660 3509bfd291fda8189e2a9b1ac0f7031d 280 Gene3D G3DSA:3.20.20.150 4 277 5.5E-52 T 12-10-2018 AFR_02250 c31d778341be413ec915f512656596a4 724 Pfam PF00535 Glycosyl transferase family 2 5 132 1.7E-36 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_02250 c31d778341be413ec915f512656596a4 724 Gene3D G3DSA:3.40.50.12580 531 705 1.0E-94 T 12-10-2018 AFR_02250 c31d778341be413ec915f512656596a4 724 Gene3D G3DSA:3.90.550.10 1 200 1.6E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02250 c31d778341be413ec915f512656596a4 724 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 355 718 4.4E-110 T 12-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 AFR_02250 c31d778341be413ec915f512656596a4 724 Gene3D G3DSA:3.40.50.11820 362 712 1.0E-94 T 12-10-2018 AFR_02250 c31d778341be413ec915f512656596a4 724 SUPERFAMILY SSF53756 518 717 4.71E-8 T 12-10-2018 AFR_02250 c31d778341be413ec915f512656596a4 724 SUPERFAMILY SSF53448 2 225 1.79E-53 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_12140 55f7786934ec9fee3d022bfc2d661d71 112 Pfam PF04956 TrbC/VIRB2 family 7 104 3.7E-7 T 12-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 AFR_12140 55f7786934ec9fee3d022bfc2d661d71 112 PIRSF PIRSF000178 1 108 2.8E-5 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_07710 af641af61204669de66245064f8b2b2f 836 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 3 835 4.9E-281 T 12-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 AFR_07710 af641af61204669de66245064f8b2b2f 836 SUPERFAMILY SSF63737 2 189 2.22E-37 T 12-10-2018 AFR_07710 af641af61204669de66245064f8b2b2f 836 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 128 143 9.1E-25 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07710 af641af61204669de66245064f8b2b2f 836 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 253 263 9.1E-25 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07710 af641af61204669de66245064f8b2b2f 836 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 306 318 9.1E-25 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07710 af641af61204669de66245064f8b2b2f 836 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 172 187 9.1E-25 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07710 af641af61204669de66245064f8b2b2f 836 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 287 302 9.1E-25 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07710 af641af61204669de66245064f8b2b2f 836 SUPERFAMILY SSF55486 196 446 4.54E-71 T 12-10-2018 AFR_07710 af641af61204669de66245064f8b2b2f 836 Gene3D G3DSA:2.60.40.1730 16 190 2.7E-22 T 12-10-2018 AFR_07710 af641af61204669de66245064f8b2b2f 836 Gene3D G3DSA:1.10.390.60 192 440 9.0E-70 T 12-10-2018 AFR_07710 af641af61204669de66245064f8b2b2f 836 Pfam PF01433 Peptidase family M1 domain 203 436 3.8E-59 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_07710 af641af61204669de66245064f8b2b2f 836 Pfam PF11838 ERAP1-like C-terminal domain 523 830 2.4E-42 T 12-10-2018 IPR024571 ERAP1-like C-terminal domain AFR_12555 c1358886550e8893833af2f1995d2c2f 522 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 329 352 9.4E-35 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 353 367 9.4E-35 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 289 309 9.4E-35 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 229 243 9.4E-35 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 310 327 9.4E-35 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Gene3D G3DSA:2.80.10.50 397 520 1.4E-35 T 12-10-2018 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Gene3D G3DSA:2.40.10.10 204 387 6.5E-63 T 12-10-2018 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 SUPERFAMILY SSF50494 208 382 9.25E-34 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Pfam PF02983 Alpha-lytic protease prodomain 128 185 3.9E-13 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 SUPERFAMILY SSF50370 396 520 5.3E-34 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Gene3D G3DSA:2.40.10.10 277 376 6.5E-63 T 12-10-2018 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Gene3D G3DSA:3.30.300.50 125 195 3.8E-8 T 12-10-2018 IPR035070 Streptogrisin prodomain AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Pfam PF00652 Ricin-type beta-trefoil lectin domain 398 519 4.4E-25 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Gene3D G3DSA:3.30.300.50 46 124 4.7E-13 T 12-10-2018 IPR035070 Streptogrisin prodomain AFR_12555 c1358886550e8893833af2f1995d2c2f 522 Pfam PF00089 Trypsin 261 381 1.5E-5 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_12555 c1358886550e8893833af2f1995d2c2f 522 SMART SM00458 397 522 5.6E-31 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 4.5E-36 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 Gene3D G3DSA:3.30.360.10 152 315 5.5E-152 T 12-10-2018 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 PIRSF PIRSF000149 1 330 1.3E-133 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 SUPERFAMILY SSF51735 3 168 1.25E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 4.8E-134 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 8.2E-69 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 SUPERFAMILY SSF55347 153 314 2.62E-71 T 12-10-2018 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.0E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.0E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.0E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.0E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.0E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 SMART SM00846 3 153 4.4E-90 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10565 de5c60f3f80a2fa1e5d45472b715323a 331 Gene3D G3DSA:3.40.50.720 4 327 5.5E-152 T 12-10-2018 AFR_27365 7f2f761e6910bf217475cda4cecc77ee 313 Gene3D G3DSA:1.10.3720.10 70 313 5.0E-73 T 12-10-2018 IPR035906 MetI-like superfamily AFR_27365 7f2f761e6910bf217475cda4cecc77ee 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 304 9.8E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_27365 7f2f761e6910bf217475cda4cecc77ee 313 SUPERFAMILY SSF161098 74 301 3.66E-63 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36840 ca2bb318f814d7384970bd3688b6f237 245 Gene3D G3DSA:3.90.190.10 12 243 1.0E-59 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFR_36840 ca2bb318f814d7384970bd3688b6f237 245 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 139 149 - T 12-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 AFR_36840 ca2bb318f814d7384970bd3688b6f237 245 Pfam PF13350 Tyrosine phosphatase family 11 242 3.7E-59 T 12-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type AFR_36840 ca2bb318f814d7384970bd3688b6f237 245 SUPERFAMILY SSF52799 11 242 6.12E-51 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 SUPERFAMILY SSF88946 3 90 5.1E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 Pfam PF04542 Sigma-70 region 2 6 70 2.1E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 153 9.8E-44 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 Gene3D G3DSA:1.10.1740.10 1 75 1.2E-13 T 12-10-2018 AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 Pfam PF08281 Sigma-70, region 4 97 145 1.8E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 149 1.6E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 SUPERFAMILY SSF88659 92 152 2.4E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 Gene3D G3DSA:1.10.10.10 91 157 2.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36350 94bf39229fce464133aa3ae23bf1ace3 167 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 28 59 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_17065 7cb1acf0d7b7f4bff3745ac87613084c 155 SUPERFAMILY SSF55961 11 153 1.98E-29 T 12-10-2018 AFR_17065 7cb1acf0d7b7f4bff3745ac87613084c 155 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 152 2.5E-16 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_17065 7cb1acf0d7b7f4bff3745ac87613084c 155 Gene3D G3DSA:3.30.530.20 2 154 8.8E-38 T 12-10-2018 IPR023393 START-like domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Pfam PF02769 AIR synthase related protein, C-terminal domain 253 402 1.4E-34 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Pfam PF02769 AIR synthase related protein, C-terminal domain 638 780 1.5E-20 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 SUPERFAMILY SSF55326 456 626 1.27E-54 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Gene3D G3DSA:3.30.1330.10 448 622 1.1E-59 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Gene3D G3DSA:3.90.650.10 77 401 1.5E-123 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Gene3D G3DSA:3.90.650.10 636 805 1.4E-37 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Gene3D G3DSA:3.30.1330.10 93 243 1.5E-123 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 SUPERFAMILY SSF56042 249 487 8.52E-53 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 SUPERFAMILY SSF56042 637 804 1.94E-36 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 SUPERFAMILY SSF55326 61 247 4.34E-46 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 812 292.769 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 66 802 1.3E-251 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Pfam PF00586 AIR synthase related protein, N-terminal domain 137 239 1.1E-21 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFR_00725 22e9f0b91f4bed334bbe35c674394e4e 915 Pfam PF00586 AIR synthase related protein, N-terminal domain 502 619 2.2E-24 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFR_19930 dadb593df527274464ea9a298560c472 252 SUPERFAMILY SSF51679 6 208 3.53E-48 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_19930 dadb593df527274464ea9a298560c472 252 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 2 248 1.7E-119 T 12-10-2018 IPR022480 F420-dependent oxidoreductase, MSMEG2906 AFR_19930 dadb593df527274464ea9a298560c472 252 Gene3D G3DSA:3.20.20.30 1 249 3.6E-50 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_19930 dadb593df527274464ea9a298560c472 252 Pfam PF00296 Luciferase-like monooxygenase 8 208 7.8E-37 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_12970 bcfa4072b898a0a9615ef79ebe6e8ead 203 SUPERFAMILY SSF48498 85 169 4.25E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12970 bcfa4072b898a0a9615ef79ebe6e8ead 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 7.4E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12970 bcfa4072b898a0a9615ef79ebe6e8ead 203 SUPERFAMILY SSF46689 8 77 1.1E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12970 bcfa4072b898a0a9615ef79ebe6e8ead 203 Gene3D G3DSA:1.10.357.10 1 195 4.1E-70 T 12-10-2018 AFR_12970 bcfa4072b898a0a9615ef79ebe6e8ead 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12970 bcfa4072b898a0a9615ef79ebe6e8ead 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04645 ccea9de4aa4a3540d915697bc8b197b3 135 ProSitePatterns PS00054 Ribosomal protein S11 signature. 103 125 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site AFR_04645 ccea9de4aa4a3540d915697bc8b197b3 135 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 135 33.671 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFR_04645 ccea9de4aa4a3540d915697bc8b197b3 135 SUPERFAMILY SSF53137 20 135 4.86E-49 T 12-10-2018 AFR_04645 ccea9de4aa4a3540d915697bc8b197b3 135 PIRSF PIRSF002131 6 135 1.1E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFR_04645 ccea9de4aa4a3540d915697bc8b197b3 135 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 16 132 4.1E-58 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04645 ccea9de4aa4a3540d915697bc8b197b3 135 Gene3D G3DSA:3.30.420.80 9 135 5.5E-54 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04645 ccea9de4aa4a3540d915697bc8b197b3 135 Pfam PF00411 Ribosomal protein S11 25 134 1.4E-48 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFR_13865 1b0cd5a8dc27dd0bdc4943e48905787a 263 SUPERFAMILY SSF48613 56 255 4.89E-10 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_13865 1b0cd5a8dc27dd0bdc4943e48905787a 263 Pfam PF14518 Iron-containing redox enzyme 76 248 9.2E-18 T 12-10-2018 AFR_13865 1b0cd5a8dc27dd0bdc4943e48905787a 263 Gene3D G3DSA:1.20.910.10 47 261 3.0E-21 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_28720 645acefad4c5e9458252b8bb727d2841 291 SMART SM00530 6 83 5.1E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_28720 645acefad4c5e9458252b8bb727d2841 291 Gene3D G3DSA:3.30.450.180 110 284 1.5E-16 T 12-10-2018 AFR_28720 645acefad4c5e9458252b8bb727d2841 291 Gene3D G3DSA:1.10.260.40 21 96 6.3E-8 T 12-10-2018 AFR_28720 645acefad4c5e9458252b8bb727d2841 291 Pfam PF13560 Helix-turn-helix domain 30 86 1.3E-11 T 12-10-2018 AFR_28720 645acefad4c5e9458252b8bb727d2841 291 SUPERFAMILY SSF47413 29 81 1.93E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Gene3D G3DSA:3.40.50.300 2 171 4.4E-44 T 12-10-2018 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 463 769 2.6E-127 T 12-10-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 SUPERFAMILY SSF56091 510 737 7.55E-13 T 12-10-2018 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Pfam PF13671 AAA domain 11 138 4.5E-23 T 12-10-2018 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Gene3D G3DSA:3.30.470.30 625 832 1.8E-68 T 12-10-2018 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 SUPERFAMILY SSF52540 11 129 4.92E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Pfam PF00149 Calcineurin-like phosphoesterase 182 377 5.9E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Gene3D G3DSA:3.60.21.10 172 425 6.3E-75 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Gene3D G3DSA:3.30.470.30 435 600 1.3E-50 T 12-10-2018 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 SUPERFAMILY SSF56300 163 419 7.25E-44 T 12-10-2018 AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 3 832 0.0 T 12-10-2018 IPR024028 Polynucleotide kinase-phosphatase, bacterial AFR_00605 43760d8157bc04f1982dfc49d680fa20 832 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 773 832 2.1E-28 T 12-10-2018 IPR032390 Polynucleotide kinase-phosphatase, C-terminal AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 Gene3D G3DSA:3.30.470.30 193 386 9.6E-48 T 12-10-2018 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 79 511 1.8E-78 T 12-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 Gene3D G3DSA:1.10.3260.10 7 192 7.3E-38 T 12-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 Pfam PF04675 DNA ligase N terminus 68 148 1.1E-8 T 12-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 SUPERFAMILY SSF117018 9 199 7.45E-26 T 12-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 219 227 - T 12-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 Pfam PF01068 ATP dependent DNA ligase domain 196 386 3.8E-39 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 Pfam PF04679 ATP dependent DNA ligase C terminal region 405 497 1.3E-13 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 SUPERFAMILY SSF56091 191 386 1.87E-39 T 12-10-2018 AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 SUPERFAMILY SSF50249 389 510 5.23E-33 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_07325 4b98658a43fa23f1adec85e90a6ddb38 517 Gene3D G3DSA:2.40.50.140 387 515 2.5E-34 T 12-10-2018 AFR_39660 1f9ff8e5c676ed9ad6b5ba9d0b961c40 711 SUPERFAMILY SSF75005 9 333 3.27E-64 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_39660 1f9ff8e5c676ed9ad6b5ba9d0b961c40 711 SUPERFAMILY SSF49899 513 708 3.64E-13 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_39660 1f9ff8e5c676ed9ad6b5ba9d0b961c40 711 Gene3D G3DSA:2.115.10.20 27 334 1.0E-72 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_39660 1f9ff8e5c676ed9ad6b5ba9d0b961c40 711 Pfam PF04616 Glycosyl hydrolases family 43 23 332 8.1E-48 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_39660 1f9ff8e5c676ed9ad6b5ba9d0b961c40 711 Gene3D G3DSA:2.60.120.200 512 710 1.5E-18 T 12-10-2018 AFR_03590 03db8c1e49fb28b75197547cf195cd1f 479 SUPERFAMILY SSF75011 153 446 8.89E-6 T 12-10-2018 AFR_03590 03db8c1e49fb28b75197547cf195cd1f 479 Pfam PF08309 LVIVD repeat 77 106 7.1E-4 T 12-10-2018 IPR013211 LVIVD AFR_03590 03db8c1e49fb28b75197547cf195cd1f 479 Pfam PF08309 LVIVD repeat 148 173 0.087 T 12-10-2018 IPR013211 LVIVD AFR_04345 f53fb13f09c2078231103971112e546d 116 Pfam PF03795 YCII-related domain 1 115 2.7E-15 T 12-10-2018 IPR005545 YCII-related AFR_04345 f53fb13f09c2078231103971112e546d 116 Gene3D G3DSA:3.30.70.1060 1 116 1.2E-32 T 12-10-2018 AFR_04345 f53fb13f09c2078231103971112e546d 116 SUPERFAMILY SSF54909 1 115 2.5E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_03435 522dfec4e7cd2db586e83cc865290072 225 SUPERFAMILY SSF46894 143 219 2.58E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 SMART SM00421 155 212 7.0E-29 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 SUPERFAMILY SSF52172 2 133 2.28E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_03435 522dfec4e7cd2db586e83cc865290072 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 1.1E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 Gene3D G3DSA:3.40.50.12740 3 218 2.1E-71 T 12-10-2018 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 Pfam PF00072 Response regulator receiver domain 5 119 1.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03435 522dfec4e7cd2db586e83cc865290072 225 SMART SM00448 3 118 2.4E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 Gene3D G3DSA:3.40.50.720 48 183 1.4E-29 T 12-10-2018 AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 105 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 136 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 SUPERFAMILY SSF51735 50 187 3.48E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 136 2.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 107 2.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 Pfam PF00106 short chain dehydrogenase 49 158 1.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12205 550eebc7d3315a22840d3fcaf7048b02 194 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 104 132 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_38500 3edc8beff432acfe300b0b7bec9315c3 223 SUPERFAMILY SSF102405 7 211 1.53E-64 T 12-10-2018 AFR_38500 3edc8beff432acfe300b0b7bec9315c3 223 Gene3D G3DSA:3.40.50.450 15 214 3.7E-68 T 12-10-2018 AFR_38500 3edc8beff432acfe300b0b7bec9315c3 223 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 38 209 1.7E-44 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG AFR_38500 3edc8beff432acfe300b0b7bec9315c3 223 Pfam PF03641 Possible lysine decarboxylase 80 209 2.5E-34 T 12-10-2018 IPR031100 LOG family AFR_22595 1ec4780d1c8543da31cd9c19d6229f01 128 SUPERFAMILY SSF54593 4 122 1.88E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_22595 1ec4780d1c8543da31cd9c19d6229f01 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 69 115 1.1E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_22595 1ec4780d1c8543da31cd9c19d6229f01 128 Gene3D G3DSA:3.10.180.10 9 120 9.8E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_24305 45ed826629e43192f316f1eea1a64efb 325 SUPERFAMILY SSF53335 108 293 9.11E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_24305 45ed826629e43192f316f1eea1a64efb 325 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 215 221 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFR_24305 45ed826629e43192f316f1eea1a64efb 325 Gene3D G3DSA:3.40.50.150 112 282 6.1E-34 T 12-10-2018 AFR_24305 45ed826629e43192f316f1eea1a64efb 325 Pfam PF05175 Methyltransferase small domain 138 261 9.1E-18 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFR_10990 7cff418dbdd7d9cb27b8f70ee8c4a53f 612 Pfam PF03703 Bacterial PH domain 64 143 5.9E-16 T 12-10-2018 IPR005182 Domain of unknown function DUF304 AFR_10990 7cff418dbdd7d9cb27b8f70ee8c4a53f 612 Pfam PF03703 Bacterial PH domain 355 424 9.1E-13 T 12-10-2018 IPR005182 Domain of unknown function DUF304 AFR_10990 7cff418dbdd7d9cb27b8f70ee8c4a53f 612 Pfam PF03703 Bacterial PH domain 246 296 8.9E-7 T 12-10-2018 IPR005182 Domain of unknown function DUF304 AFR_35475 50ca64b76c2401420b92d054e3ffa869 261 SMART SM00342 170 255 6.7E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_35475 50ca64b76c2401420b92d054e3ffa869 261 Gene3D G3DSA:1.10.10.60 154 260 4.9E-22 T 12-10-2018 AFR_35475 50ca64b76c2401420b92d054e3ffa869 261 SUPERFAMILY SSF46689 208 258 8.06E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_35475 50ca64b76c2401420b92d054e3ffa869 261 Pfam PF12833 Helix-turn-helix domain 177 257 6.5E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_40000 d23e89db1761e9b60f1b1614bf0727b1 119 SUPERFAMILY SSF51735 1 111 5.45E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40000 d23e89db1761e9b60f1b1614bf0727b1 119 SMART SM00881 1 84 9.0E-13 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_40000 d23e89db1761e9b60f1b1614bf0727b1 119 Gene3D G3DSA:3.40.50.720 1 117 2.3E-37 T 12-10-2018 AFR_40000 d23e89db1761e9b60f1b1614bf0727b1 119 Pfam PF13380 CoA binding domain 1 109 9.0E-36 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFR_40775 dbc7caa262b9ed3199f02ac34ff839bc 348 SUPERFAMILY SSF161098 80 336 2.62E-40 T 12-10-2018 IPR035906 MetI-like superfamily AFR_40775 dbc7caa262b9ed3199f02ac34ff839bc 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 343 1.0E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_40775 dbc7caa262b9ed3199f02ac34ff839bc 348 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 71 345 1.4E-82 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AFR_40775 dbc7caa262b9ed3199f02ac34ff839bc 348 Gene3D G3DSA:1.10.3720.10 121 346 3.7E-34 T 12-10-2018 IPR035906 MetI-like superfamily AFR_12630 56cc250f213703ede5a3609144398777 439 SUPERFAMILY SSF63380 219 312 4.48E-19 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_12630 56cc250f213703ede5a3609144398777 439 Pfam PF08022 FAD-binding domain 224 298 3.1E-10 T 12-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 AFR_12630 56cc250f213703ede5a3609144398777 439 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 259 2.9E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_12630 56cc250f213703ede5a3609144398777 439 PRINTS PR00410 Phenol hydroxylase reductase family signature 307 316 2.9E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_12630 56cc250f213703ede5a3609144398777 439 PRINTS PR00410 Phenol hydroxylase reductase family signature 322 341 2.9E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_12630 56cc250f213703ede5a3609144398777 439 PRINTS PR00410 Phenol hydroxylase reductase family signature 404 412 2.9E-9 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_12630 56cc250f213703ede5a3609144398777 439 Gene3D G3DSA:3.40.50.80 314 439 3.2E-21 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_12630 56cc250f213703ede5a3609144398777 439 SUPERFAMILY SSF52343 317 436 6.16E-20 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_12630 56cc250f213703ede5a3609144398777 439 Gene3D G3DSA:2.40.30.10 216 310 2.9E-14 T 12-10-2018 AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 Gene3D G3DSA:3.50.50.60 3 336 2.4E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 Gene3D G3DSA:3.30.9.20 40 252 2.4E-116 T 12-10-2018 AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 Pfam PF01494 FAD binding domain 107 319 6.2E-15 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 SUPERFAMILY SSF51905 5 342 1.88E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 7.3E-12 T 12-10-2018 AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 128 143 7.3E-12 T 12-10-2018 AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 263 278 7.3E-12 T 12-10-2018 AFR_11680 ba650cd7596de8ab10bfa63549a6072a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 294 7.3E-12 T 12-10-2018 AFR_07900 4c6bcb89443991f08a02ddab7c32184b 225 SUPERFAMILY SSF81301 79 224 1.37E-10 T 12-10-2018 AFR_07900 4c6bcb89443991f08a02ddab7c32184b 225 Gene3D G3DSA:3.30.460.40 77 225 3.0E-26 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Gene3D G3DSA:3.30.70.870 332 400 6.6E-7 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Pfam PF00679 Elongation factor G C-terminus 527 608 1.5E-14 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 SMART SM00889 402 524 5.9E-9 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 SUPERFAMILY SSF54980 332 400 1.08E-9 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 SUPERFAMILY SSF54211 396 524 8.72E-12 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Gene3D G3DSA:2.40.30.10 244 328 4.1E-8 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Gene3D G3DSA:3.40.50.300 3 243 9.6E-64 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Pfam PF00009 Elongation factor Tu GTP binding domain 4 236 2.4E-50 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Pfam PF03764 Elongation factor G, domain IV 396 523 3.9E-11 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR00315 GTP-binding elongation factor signature 123 132 3.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR00315 GTP-binding elongation factor signature 87 98 3.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR00315 GTP-binding elongation factor signature 51 59 3.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR00315 GTP-binding elongation factor signature 71 81 3.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR00315 GTP-binding elongation factor signature 5 18 3.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 SUPERFAMILY SSF50447 220 323 1.57E-14 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 SUPERFAMILY SSF54980 527 610 2.69E-14 T 12-10-2018 IPR035647 EF-G domain III/V-like AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 SUPERFAMILY SSF52540 4 236 3.28E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Gene3D G3DSA:3.30.70.240 530 600 3.7E-21 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 Gene3D G3DSA:3.30.230.10 428 606 3.7E-21 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 144 3.3E-26 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 264 290 1.4E-20 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 1.4E-20 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 210 232 1.4E-20 T 12-10-2018 AFR_21510 3d87ac2d949efb541fa539fb7d4848b2 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 450 472 1.4E-20 T 12-10-2018 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.4E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.4E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.4E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 SMART SM00422 1 69 1.0E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 Pfam PF13411 MerR HTH family regulatory protein 1 61 8.1E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 Pfam PF08534 Redoxin 134 280 3.8E-9 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 Gene3D G3DSA:3.40.30.10 133 297 6.4E-15 T 12-10-2018 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 Gene3D G3DSA:1.10.1660.10 1 120 1.3E-24 T 12-10-2018 AFR_22740 751d7221614e2c42e2df493605c4f46a 307 SUPERFAMILY SSF46955 1 114 5.13E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_22740 751d7221614e2c42e2df493605c4f46a 307 SUPERFAMILY SSF52833 132 292 8.57E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_21485 1b292c9f05d8ca462d265c843a0ddc99 139 Gene3D G3DSA:2.20.25.10 1 44 8.3E-20 T 12-10-2018 AFR_21485 1b292c9f05d8ca462d265c843a0ddc99 139 SUPERFAMILY SSF82784 1 138 4.84E-43 T 12-10-2018 IPR036102 OsmC/Ohr superfamily AFR_21485 1b292c9f05d8ca462d265c843a0ddc99 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 138 1.1E-53 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 AFR_21485 1b292c9f05d8ca462d265c843a0ddc99 139 Gene3D G3DSA:3.30.300.20 46 139 1.9E-34 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_21485 1b292c9f05d8ca462d265c843a0ddc99 139 Pfam PF02566 OsmC-like protein 43 136 6.8E-20 T 12-10-2018 IPR003718 OsmC/Ohr family AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Pfam PF06439 Domain of Unknown Function (DUF1080) 1075 1288 3.4E-31 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Gene3D G3DSA:2.60.120.560 1067 1290 2.0E-34 T 12-10-2018 AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 SUPERFAMILY SSF50952 411 719 2.62E-13 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 SUPERFAMILY SSF49299 919 987 2.62E-16 T 12-10-2018 IPR035986 PKD domain superfamily AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Gene3D G3DSA:2.60.40.10 909 989 6.2E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Pfam PF00801 PKD domain 917 977 1.9E-9 T 12-10-2018 IPR000601 PKD domain AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Pfam PF06283 Trehalose utilisation 23 379 2.7E-74 T 12-10-2018 IPR029010 ThuA-like domain AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 SUPERFAMILY SSF52317 20 148 1.56E-12 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Pfam PF07995 Glucose / Sorbosone dehydrogenase 482 706 1.8E-19 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Gene3D G3DSA:3.40.50.880 262 390 3.0E-32 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Gene3D G3DSA:3.40.50.880 7 170 2.1E-25 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 SUPERFAMILY SSF52317 279 386 6.87E-17 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Pfam PF00754 F5/8 type C domain 140 250 5.5E-12 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 Gene3D G3DSA:2.120.10.30 393 757 1.5E-53 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 SUPERFAMILY SSF49785 129 265 2.84E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15620 4a86101586d92c33df186bda56c0fb73 1290 SMART SM00089 910 990 2.0E-11 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_40265 2d96efbe02b5a997f260d82f8840bb8c 297 Pfam PF00106 short chain dehydrogenase 4 132 1.7E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40265 2d96efbe02b5a997f260d82f8840bb8c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40265 2d96efbe02b5a997f260d82f8840bb8c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40265 2d96efbe02b5a997f260d82f8840bb8c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 3.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40265 2d96efbe02b5a997f260d82f8840bb8c 297 Gene3D G3DSA:3.40.50.720 2 294 6.2E-46 T 12-10-2018 AFR_40265 2d96efbe02b5a997f260d82f8840bb8c 297 SUPERFAMILY SSF51735 3 267 1.1E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41620 905d5532611fc7ef78a434f7af949a77 668 Pfam PF00364 Biotin-requiring enzyme 605 665 8.7E-14 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_41620 905d5532611fc7ef78a434f7af949a77 668 SUPERFAMILY SSF51230 594 665 1.7E-17 T 12-10-2018 IPR011053 Single hybrid motif AFR_41620 905d5532611fc7ef78a434f7af949a77 668 Gene3D G3DSA:3.30.470.130 1 443 3.6E-154 T 12-10-2018 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 Pfam PF02785 Biotin carboxylase C-terminal domain 320 436 6.6E-27 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 SUPERFAMILY SSF56059 84 316 2.83E-51 T 12-10-2018 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 4.6E-36 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 622 639 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 141 307 4.2E-50 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 SMART SM00878 320 435 4.4E-38 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 SUPERFAMILY SSF51246 315 441 5.23E-32 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 143 157 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 Gene3D G3DSA:2.40.50.100 592 666 2.4E-19 T 12-10-2018 AFR_41620 905d5532611fc7ef78a434f7af949a77 668 SUPERFAMILY SSF52440 2 112 6.19E-39 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 Gene3D G3DSA:3.40.50.1460 5 203 2.2E-11 T 12-10-2018 AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 Pfam PF13531 Bacterial extracellular solute-binding protein 269 558 5.4E-12 T 12-10-2018 AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 SUPERFAMILY SSF53300 609 770 5.25E-20 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 Pfam PF13519 von Willebrand factor type A domain 610 722 2.1E-10 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 ProSitePatterns PS00018 EF-hand calcium-binding domain. 156 168 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 SMART SM00327 606 778 1.0E-15 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 Pfam PF00656 Caspase domain 7 193 3.3E-5 T 12-10-2018 AFR_26070 c9680329ed8ab4fc3eb4b91e3ea40427 790 Gene3D G3DSA:3.40.50.410 609 780 2.5E-28 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_23015 a485f8704f06352a7441895cf3438d2b 232 Gene3D G3DSA:3.40.50.1820 1 231 5.1E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23015 a485f8704f06352a7441895cf3438d2b 232 SUPERFAMILY SSF53474 3 230 3.92E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23015 a485f8704f06352a7441895cf3438d2b 232 Pfam PF12697 Alpha/beta hydrolase family 3 228 3.2E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_31635 c1e3d988fa2dc9c118c3d757fca8afea 258 SUPERFAMILY SSF51735 22 254 4.0E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_31635 c1e3d988fa2dc9c118c3d757fca8afea 258 Gene3D G3DSA:3.40.50.720 1 251 6.9E-38 T 12-10-2018 AFR_31635 c1e3d988fa2dc9c118c3d757fca8afea 258 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 179 1.0E-16 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_20815 b40956acc181113fc9a1dcb5dabb0014 98 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 9 98 1.5E-43 T 12-10-2018 IPR009359 Phenylacetic acid degradation B AFR_20815 b40956acc181113fc9a1dcb5dabb0014 98 PIRSF PIRSF030200 1 98 2.8E-42 T 12-10-2018 IPR009359 Phenylacetic acid degradation B AFR_20815 b40956acc181113fc9a1dcb5dabb0014 98 Gene3D G3DSA:3.10.20.520 4 68 2.6E-30 T 12-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B AFR_20815 b40956acc181113fc9a1dcb5dabb0014 98 Pfam PF06243 Phenylacetic acid degradation B 8 94 1.3E-38 T 12-10-2018 IPR009359 Phenylacetic acid degradation B AFR_23115 5482955fe5c650d100fe5f3fa08b8f54 282 Gene3D G3DSA:3.20.20.30 1 281 1.9E-58 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_23115 5482955fe5c650d100fe5f3fa08b8f54 282 SUPERFAMILY SSF51679 4 271 1.7E-55 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_23115 5482955fe5c650d100fe5f3fa08b8f54 282 Pfam PF00296 Luciferase-like monooxygenase 25 236 1.8E-41 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 236 7.5E-28 T 12-10-2018 AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 8.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 8.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 8.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 8.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 Gene3D G3DSA:3.40.50.720 1 239 5.6E-39 T 12-10-2018 AFR_23025 fb8eccae0e70ef40c064be3c3992d30f 240 SUPERFAMILY SSF51735 1 239 9.54E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_01035 30c97d8f2866983fcf8e37cf42802d5e 426 Gene3D G3DSA:1.10.10.10 122 171 3.4E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01035 30c97d8f2866983fcf8e37cf42802d5e 426 SUPERFAMILY SSF88659 110 169 1.74E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_01035 30c97d8f2866983fcf8e37cf42802d5e 426 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 169 7.8E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_01035 30c97d8f2866983fcf8e37cf42802d5e 426 Gene3D G3DSA:1.10.1740.10 1 75 4.3E-8 T 12-10-2018 AFR_01035 30c97d8f2866983fcf8e37cf42802d5e 426 SUPERFAMILY SSF88946 5 93 5.49E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_01035 30c97d8f2866983fcf8e37cf42802d5e 426 Pfam PF08281 Sigma-70, region 4 118 167 1.1E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_01035 30c97d8f2866983fcf8e37cf42802d5e 426 Pfam PF04542 Sigma-70 region 2 18 78 1.9E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_06440 f3b476935dc928b474e2201be6c7f7f3 307 Gene3D G3DSA:2.40.40.10 42 141 1.8E-27 T 12-10-2018 IPR036908 RlpA-like domain superfamily AFR_06440 f3b476935dc928b474e2201be6c7f7f3 307 SUPERFAMILY SSF50685 38 142 9.07E-22 T 12-10-2018 IPR036908 RlpA-like domain superfamily AFR_06440 f3b476935dc928b474e2201be6c7f7f3 307 Pfam PF03330 Lytic transglycolase 85 137 9.8E-10 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFR_06440 f3b476935dc928b474e2201be6c7f7f3 307 SUPERFAMILY SSF49590 149 224 3.66E-10 T 12-10-2018 IPR036749 Expansin, cellulose-binding-like domain superfamily AFR_06440 f3b476935dc928b474e2201be6c7f7f3 307 Gene3D G3DSA:2.60.40.760 145 234 2.6E-22 T 12-10-2018 IPR036749 Expansin, cellulose-binding-like domain superfamily AFR_02665 dbd7775ff72394624d0cabc4c35fd8aa 349 SUPERFAMILY SSF53756 17 345 6.51E-11 T 12-10-2018 AFR_02665 dbd7775ff72394624d0cabc4c35fd8aa 349 Gene3D G3DSA:3.40.50.11190 3 148 3.1E-16 T 12-10-2018 AFR_02665 dbd7775ff72394624d0cabc4c35fd8aa 349 Gene3D G3DSA:3.40.50.2000 149 285 1.2E-15 T 12-10-2018 AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 26 34 - T 12-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 Gene3D G3DSA:3.30.1490.70 19 193 1.8E-52 T 12-10-2018 AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 Gene3D G3DSA:3.30.470.30 31 150 1.8E-52 T 12-10-2018 AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 Pfam PF01068 ATP dependent DNA ligase domain 20 194 1.9E-29 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 Gene3D G3DSA:2.40.50.140 197 316 1.1E-35 T 12-10-2018 AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 SUPERFAMILY SSF50249 198 317 2.23E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 9 314 2.2E-79 T 12-10-2018 IPR014146 DNA ligase D, ligase domain AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 Pfam PF04679 ATP dependent DNA ligase C terminal region 214 309 1.6E-22 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AFR_28570 2bc62e5a63071b11addb364f7df78c9e 389 SUPERFAMILY SSF56091 7 194 1.3E-44 T 12-10-2018 AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 SUPERFAMILY SSF50104 2 100 3.5E-28 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 SMART SM00739 2 29 1.2E-4 T 12-10-2018 IPR005824 KOW AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 Pfam PF00467 KOW motif 5 36 2.9E-7 T 12-10-2018 IPR005824 KOW AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 98 20.598 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 Gene3D G3DSA:2.30.30.30 1 103 9.2E-34 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 103 7.2E-36 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04560 1dcea6d2eb8e0b22042bc9f7fd75c093 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 103 1.1E-21 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_09005 f75fe8c0095118ea91e442bd4b035449 266 Pfam PF13847 Methyltransferase domain 34 147 3.0E-26 T 12-10-2018 IPR025714 Methyltransferase domain AFR_09005 f75fe8c0095118ea91e442bd4b035449 266 SUPERFAMILY SSF53335 5 248 6.14E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_09005 f75fe8c0095118ea91e442bd4b035449 266 Gene3D G3DSA:3.40.50.150 2 254 2.9E-43 T 12-10-2018 AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 6.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 6.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 179 0.0048 T 12-10-2018 AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 Pfam PF00106 short chain dehydrogenase 3 185 1.4E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 Gene3D G3DSA:3.40.50.720 2 265 9.1E-70 T 12-10-2018 AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 4.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 4.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 4.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16360 b0e0c6281cdfbae21c86f159681f864b 267 SUPERFAMILY SSF51735 2 242 8.06E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29345 6b9df70c97161a5d5776e43377edefba 178 Gene3D G3DSA:1.10.357.10 4 178 3.7E-29 T 12-10-2018 AFR_29345 6b9df70c97161a5d5776e43377edefba 178 SUPERFAMILY SSF46689 5 83 1.39E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29345 6b9df70c97161a5d5776e43377edefba 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.7E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29345 6b9df70c97161a5d5776e43377edefba 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29345 6b9df70c97161a5d5776e43377edefba 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 SMART SM00304 79 132 5.2E-5 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 SMART SM00388 133 199 7.8E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 Gene3D G3DSA:1.10.287.130 83 199 3.8E-19 T 12-10-2018 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 SUPERFAMILY SSF158472 79 127 1.83E-5 T 12-10-2018 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 328 1.3E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 275 289 1.3E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 303 1.3E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 SUPERFAMILY SSF47384 116 198 5.49E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 243 347 8.3E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 SUPERFAMILY SSF55874 202 347 1.44E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 SMART SM00387 241 350 4.9E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 Gene3D G3DSA:3.30.565.10 204 349 8.8E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28500 ba21a6f7b6dd0c67ab98835faae40c98 359 Pfam PF00512 His Kinase A (phospho-acceptor) domain 133 198 1.7E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_20775 a50997c990b09e89023044185acd3fce 435 Gene3D G3DSA:3.40.50.12780 3 330 4.1E-136 T 12-10-2018 AFR_20775 a50997c990b09e89023044185acd3fce 435 PIRSF PIRSF006444 4 434 8.7E-201 T 12-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AFR_20775 a50997c990b09e89023044185acd3fce 435 SUPERFAMILY SSF56801 24 391 4.32E-60 T 12-10-2018 AFR_20775 a50997c990b09e89023044185acd3fce 435 Gene3D G3DSA:3.30.300.30 331 433 1.8E-27 T 12-10-2018 AFR_20775 a50997c990b09e89023044185acd3fce 435 Pfam PF00501 AMP-binding enzyme 97 294 1.5E-14 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_20775 a50997c990b09e89023044185acd3fce 435 Pfam PF14535 AMP-binding enzyme C-terminal domain 339 432 5.0E-24 T 12-10-2018 IPR028154 AMP-dependent ligase, C-terminal AFR_20775 a50997c990b09e89023044185acd3fce 435 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 15 432 2.0E-211 T 12-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AFR_08920 fced636d94276517d74998c6ab62c2a2 153 Pfam PF01047 MarR family 38 92 6.0E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_08920 fced636d94276517d74998c6ab62c2a2 153 Gene3D G3DSA:1.10.10.10 6 144 4.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08920 fced636d94276517d74998c6ab62c2a2 153 SUPERFAMILY SSF46785 23 143 1.03E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_08920 fced636d94276517d74998c6ab62c2a2 153 SMART SM00347 31 129 1.3E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_08920 fced636d94276517d74998c6ab62c2a2 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.9E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_08920 fced636d94276517d74998c6ab62c2a2 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.9E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_08920 fced636d94276517d74998c6ab62c2a2 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.9E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_08920 fced636d94276517d74998c6ab62c2a2 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.9E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_35360 9e975d944f3eb51f74dd8a5305659637 113 Pfam PF11298 Protein of unknown function (DUF3099) 7 80 1.5E-24 T 12-10-2018 IPR021449 Protein of unknown function DUF3099 AFR_15815 56b9b0ec52c9b3166e17ad18733e892b 1055 SUPERFAMILY SSF69318 738 1040 4.97E-18 T 12-10-2018 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 SUPERFAMILY SSF51338 414 484 1.23E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 572 1.8E-264 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 Hamap MF_01953 Urease subunit alpha [ureC]. 2 572 54.774 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 Pfam PF01979 Amidohydrolase family 131 459 7.0E-67 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 ProSitePatterns PS00145 Urease active site. 323 339 - T 12-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 Gene3D G3DSA:2.30.40.10 5 485 1.7E-284 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 125 1.1E-53 T 12-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 SUPERFAMILY SSF51556 135 572 4.77E-180 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 Gene3D G3DSA:3.20.20.140 135 572 1.7E-284 T 12-10-2018 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 ProSitePatterns PS01120 Urease nickel ligands signature. 133 146 - T 12-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 432 445 2.1E-31 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 406 421 2.1E-31 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 301 318 2.1E-31 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 340 356 2.1E-31 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30915 a5db504a9bb21b45553b8dfcb8cded60 572 SUPERFAMILY SSF51338 3 182 2.38E-57 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_15010 7342c8c60182a70223e843e55be85d6e 130 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 117 4.8E-7 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_15010 7342c8c60182a70223e843e55be85d6e 130 SUPERFAMILY SSF69118 4 117 3.45E-12 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_15010 7342c8c60182a70223e843e55be85d6e 130 Gene3D G3DSA:1.20.1290.10 2 121 7.2E-12 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_25375 17fcce177e2f0316ec87bd7ecf8a8707 321 SUPERFAMILY SSF51445 12 318 2.42E-59 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_25375 17fcce177e2f0316ec87bd7ecf8a8707 321 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 231 248 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AFR_25375 17fcce177e2f0316ec87bd7ecf8a8707 321 Gene3D G3DSA:3.20.20.300 1 315 1.2E-84 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_25375 17fcce177e2f0316ec87bd7ecf8a8707 321 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 12 311 2.3E-47 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 9.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 Gene3D G3DSA:3.40.50.12740 8 216 9.2E-64 T 12-10-2018 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 SUPERFAMILY SSF52172 7 135 2.42E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 SMART SM00448 8 121 1.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 SMART SM00421 154 211 1.2E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 SUPERFAMILY SSF46894 147 216 1.84E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_14065 2756f5da7d9de6cabce65e90007c37db 222 Pfam PF00072 Response regulator receiver domain 10 121 2.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_09350 21a6d11a3af3e321a7a3f3bd4045f7a2 389 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 56 388 2.6E-97 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFR_09350 21a6d11a3af3e321a7a3f3bd4045f7a2 389 SUPERFAMILY SSF142754 51 388 4.45E-95 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFR_09350 21a6d11a3af3e321a7a3f3bd4045f7a2 389 Pfam PF02445 Quinolinate synthetase A protein 57 387 1.4E-104 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFR_09350 21a6d11a3af3e321a7a3f3bd4045f7a2 389 Gene3D G3DSA:3.40.50.10800 130 386 3.7E-78 T 12-10-2018 AFR_09350 21a6d11a3af3e321a7a3f3bd4045f7a2 389 Hamap MF_00569 Quinolinate synthase A [nadA]. 40 388 54.633 T 12-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFR_09350 21a6d11a3af3e321a7a3f3bd4045f7a2 389 Gene3D G3DSA:3.40.50.10800 58 369 3.7E-78 T 12-10-2018 AFR_09350 21a6d11a3af3e321a7a3f3bd4045f7a2 389 Gene3D G3DSA:3.40.50.10800 251 339 3.7E-78 T 12-10-2018 AFR_15055 91203b4bce7968645938b793a2520f1f 249 SMART SM00382 28 215 7.7E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_15055 91203b4bce7968645938b793a2520f1f 249 Pfam PF00005 ABC transporter 19 158 5.0E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_15055 91203b4bce7968645938b793a2520f1f 249 SUPERFAMILY SSF52540 4 222 4.05E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15055 91203b4bce7968645938b793a2520f1f 249 Gene3D G3DSA:3.40.50.300 1 233 4.3E-52 T 12-10-2018 AFR_15055 91203b4bce7968645938b793a2520f1f 249 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_34300 82b4f3222b7fe124ed05dbab5549f62a 440 Gene3D G3DSA:1.10.510.10 92 265 4.5E-36 T 12-10-2018 AFR_34300 82b4f3222b7fe124ed05dbab5549f62a 440 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_34300 82b4f3222b7fe124ed05dbab5549f62a 440 SMART SM00220 10 254 6.2E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_34300 82b4f3222b7fe124ed05dbab5549f62a 440 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_34300 82b4f3222b7fe124ed05dbab5549f62a 440 Pfam PF00069 Protein kinase domain 10 226 9.8E-37 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_34300 82b4f3222b7fe124ed05dbab5549f62a 440 Gene3D G3DSA:3.30.200.20 2 90 5.8E-23 T 12-10-2018 AFR_34300 82b4f3222b7fe124ed05dbab5549f62a 440 SUPERFAMILY SSF56112 7 252 2.29E-59 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 Gene3D G3DSA:1.20.120.530 79 218 6.9E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 SMART SM00895 85 209 3.2E-21 T 12-10-2018 IPR011711 GntR, C-terminal AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 SUPERFAMILY SSF46785 10 105 1.09E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 Pfam PF07729 FCD domain 86 208 2.3E-26 T 12-10-2018 IPR011711 GntR, C-terminal AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 SUPERFAMILY SSF48008 81 215 3.66E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 SMART SM00345 17 75 7.7E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 Gene3D G3DSA:1.10.10.10 6 76 2.4E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17910 ff6c36134aea043cd8e51cdeaac43d37 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 5.9E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_06495 5135825764b1de288537ad98c5e1551f 179 SUPERFAMILY SSF88946 6 106 4.71E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_06495 5135825764b1de288537ad98c5e1551f 179 Gene3D G3DSA:1.10.10.10 115 175 9.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06495 5135825764b1de288537ad98c5e1551f 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 171 8.3E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_06495 5135825764b1de288537ad98c5e1551f 179 Pfam PF04542 Sigma-70 region 2 32 88 2.0E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_06495 5135825764b1de288537ad98c5e1551f 179 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 77 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_06495 5135825764b1de288537ad98c5e1551f 179 Pfam PF08281 Sigma-70, region 4 120 169 6.9E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_06495 5135825764b1de288537ad98c5e1551f 179 Gene3D G3DSA:1.10.1740.10 2 87 7.0E-29 T 12-10-2018 AFR_06495 5135825764b1de288537ad98c5e1551f 179 SUPERFAMILY SSF88659 117 170 7.85E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_00465 6af188828e7c48818ff080f5ffae155e 594 Gene3D G3DSA:3.40.30.10 4 146 7.5E-34 T 12-10-2018 AFR_00465 6af188828e7c48818ff080f5ffae155e 594 SUPERFAMILY SSF101898 162 460 1.78E-27 T 12-10-2018 AFR_00465 6af188828e7c48818ff080f5ffae155e 594 Gene3D G3DSA:2.120.10.30 303 490 8.8E-16 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_00465 6af188828e7c48818ff080f5ffae155e 594 Pfam PF13905 Thioredoxin-like 30 123 5.6E-9 T 12-10-2018 IPR012336 Thioredoxin-like fold AFR_00465 6af188828e7c48818ff080f5ffae155e 594 SUPERFAMILY SSF52833 15 160 2.15E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_00465 6af188828e7c48818ff080f5ffae155e 594 Gene3D G3DSA:2.120.10.30 147 302 5.2E-20 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_35725 558704b731b03a40a2b1781aae30237a 584 Pfam PF00069 Protein kinase domain 12 263 2.6E-46 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_35725 558704b731b03a40a2b1781aae30237a 584 Gene3D G3DSA:3.30.200.20 2 95 3.1E-29 T 12-10-2018 AFR_35725 558704b731b03a40a2b1781aae30237a 584 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_35725 558704b731b03a40a2b1781aae30237a 584 SUPERFAMILY SSF56112 8 265 6.2E-67 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_35725 558704b731b03a40a2b1781aae30237a 584 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_35725 558704b731b03a40a2b1781aae30237a 584 Gene3D G3DSA:1.10.510.10 98 281 3.8E-40 T 12-10-2018 AFR_35725 558704b731b03a40a2b1781aae30237a 584 SMART SM00220 12 269 1.4E-59 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 Gene3D G3DSA:3.40.50.300 263 429 1.4E-5 T 12-10-2018 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 99 6.3E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 Pfam PF13191 AAA ATPase domain 266 423 7.5E-26 T 12-10-2018 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 SUPERFAMILY SSF46894 7 100 2.64E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 SUPERFAMILY SSF48452 107 262 7.05E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 SMART SM01043 107 249 6.0E-33 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_14865 1b79542926bc9223fd49068a84bef307 1040 Gene3D G3DSA:1.25.40.10 106 261 6.2E-33 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 Gene3D G3DSA:1.10.10.10 2 102 1.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14865 1b79542926bc9223fd49068a84bef307 1040 SUPERFAMILY SSF52540 264 524 1.87E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14865 1b79542926bc9223fd49068a84bef307 1040 SMART SM00862 21 100 9.9E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_14865 1b79542926bc9223fd49068a84bef307 1040 Pfam PF03704 Bacterial transcriptional activator domain 108 249 3.0E-27 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_15185 0de5ecf406515dec26c0a75d6d0d570e 318 Gene3D G3DSA:1.10.10.10 3 65 1.0E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15185 0de5ecf406515dec26c0a75d6d0d570e 318 PIRSF PIRSF016838 2 55 0.86 T 12-10-2018 IPR028349 Protein PafC AFR_15185 0de5ecf406515dec26c0a75d6d0d570e 318 PIRSF PIRSF016838 63 317 9.3E-16 T 12-10-2018 IPR028349 Protein PafC AFR_15185 0de5ecf406515dec26c0a75d6d0d570e 318 Pfam PF13280 WYL domain 144 310 4.2E-31 T 12-10-2018 IPR026881 WYL domain AFR_15185 0de5ecf406515dec26c0a75d6d0d570e 318 SUPERFAMILY SSF46785 8 65 1.08E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15185 0de5ecf406515dec26c0a75d6d0d570e 318 Pfam PF08279 HTH domain 9 62 4.1E-8 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_01625 22f742e8b058234e9f283981de022a47 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 75 1.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01625 22f742e8b058234e9f283981de022a47 251 SUPERFAMILY SSF46689 19 85 3.89E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01625 22f742e8b058234e9f283981de022a47 251 SUPERFAMILY SSF48498 94 245 1.11E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_01625 22f742e8b058234e9f283981de022a47 251 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 91 240 9.2E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_01625 22f742e8b058234e9f283981de022a47 251 Gene3D G3DSA:1.10.357.10 85 245 1.3E-33 T 12-10-2018 AFR_01625 22f742e8b058234e9f283981de022a47 251 Gene3D G3DSA:1.10.10.60 5 81 1.7E-26 T 12-10-2018 AFR_38620 742d8692082ae166d63675d6c7fe7090 248 SUPERFAMILY SSF56235 2 240 5.98E-16 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_38620 742d8692082ae166d63675d6c7fe7090 248 Gene3D G3DSA:3.60.20.10 2 247 5.3E-83 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_38620 742d8692082ae166d63675d6c7fe7090 248 Pfam PF13522 Glutamine amidotransferase domain 76 216 2.4E-14 T 12-10-2018 AFR_38620 742d8692082ae166d63675d6c7fe7090 248 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 245 41.158 T 12-10-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 AFR_38620 742d8692082ae166d63675d6c7fe7090 248 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 244 1.7E-82 T 12-10-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 AFR_02425 40dcb96b86d33b2d828b6d27f476237a 339 SUPERFAMILY SSF50969 108 323 4.97E-12 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFR_35870 e980ab5030a7a6565ae3b3a94c8a230e 276 Gene3D G3DSA:1.10.3720.10 2 267 5.0E-63 T 12-10-2018 IPR035906 MetI-like superfamily AFR_35870 e980ab5030a7a6565ae3b3a94c8a230e 276 SUPERFAMILY SSF161098 3 276 1.4E-66 T 12-10-2018 IPR035906 MetI-like superfamily AFR_35870 e980ab5030a7a6565ae3b3a94c8a230e 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 268 2.2E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_00235 148bf1a728f4d7ed221cdbf8dd60f027 267 Gene3D G3DSA:1.10.260.40 1 58 1.2E-5 T 12-10-2018 AFR_00235 148bf1a728f4d7ed221cdbf8dd60f027 267 SUPERFAMILY SSF47413 2 42 3.22E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_00235 148bf1a728f4d7ed221cdbf8dd60f027 267 Pfam PF13560 Helix-turn-helix domain 2 49 6.9E-10 T 12-10-2018 AFR_25180 f4c905c726f279cdd78961fa42293627 865 Gene3D G3DSA:1.25.40.10 482 625 2.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25180 f4c905c726f279cdd78961fa42293627 865 Gene3D G3DSA:3.40.50.300 47 163 1.8E-6 T 12-10-2018 AFR_25180 f4c905c726f279cdd78961fa42293627 865 SUPERFAMILY SSF48452 486 632 1.08E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25180 f4c905c726f279cdd78961fa42293627 865 SUPERFAMILY SSF52540 61 196 1.67E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 Pfam PF00196 Bacterial regulatory proteins, luxR family 102 156 5.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 SUPERFAMILY SSF46894 89 162 3.4E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 ProSitePatterns PS00622 LuxR-type HTH domain signature. 116 143 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 SMART SM00421 99 156 6.7E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 Gene3D G3DSA:1.10.10.10 62 162 6.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 116 132 8.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 132 144 8.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11605 01a7eeb9d049a323a12ebd6fffcb602e 163 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 102 116 8.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34750 d4fae2e2010aedd398bc112827f448af 331 Gene3D G3DSA:1.10.260.40 1 54 1.2E-15 T 12-10-2018 AFR_34750 d4fae2e2010aedd398bc112827f448af 331 Gene3D G3DSA:3.40.50.2300 161 287 6.6E-55 T 12-10-2018 AFR_34750 d4fae2e2010aedd398bc112827f448af 331 Pfam PF13377 Periplasmic binding protein-like domain 169 326 3.8E-28 T 12-10-2018 AFR_34750 d4fae2e2010aedd398bc112827f448af 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 5.4E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_34750 d4fae2e2010aedd398bc112827f448af 331 SUPERFAMILY SSF47413 1 52 5.01E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_34750 d4fae2e2010aedd398bc112827f448af 331 Gene3D G3DSA:3.40.50.2300 80 310 6.6E-55 T 12-10-2018 AFR_34750 d4fae2e2010aedd398bc112827f448af 331 SUPERFAMILY SSF53822 73 311 8.25E-45 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_34750 d4fae2e2010aedd398bc112827f448af 331 SMART SM00354 1 68 9.4E-10 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_09575 716a613555c649120dc6a393905a8f7e 470 Gene3D G3DSA:3.40.50.2000 236 444 6.3E-159 T 12-10-2018 AFR_09575 716a613555c649120dc6a393905a8f7e 470 Pfam PF00982 Glycosyltransferase family 20 5 458 2.7E-140 T 12-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 AFR_09575 716a613555c649120dc6a393905a8f7e 470 SUPERFAMILY SSF53756 4 460 8.79E-139 T 12-10-2018 AFR_09575 716a613555c649120dc6a393905a8f7e 470 Gene3D G3DSA:3.40.50.2000 29 455 6.3E-159 T 12-10-2018 AFR_32560 f65626c7bd780e2cc22f38a5c62765df 331 Gene3D G3DSA:3.40.50.300 10 201 6.5E-49 T 12-10-2018 AFR_32560 f65626c7bd780e2cc22f38a5c62765df 331 PIRSF PIRSF002849 2 326 3.4E-127 T 12-10-2018 AFR_32560 f65626c7bd780e2cc22f38a5c62765df 331 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 175 2.5E-64 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_32560 f65626c7bd780e2cc22f38a5c62765df 331 Gene3D G3DSA:1.10.8.300 204 321 1.3E-33 T 12-10-2018 AFR_32560 f65626c7bd780e2cc22f38a5c62765df 331 SUPERFAMILY SSF52540 20 296 2.13E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31470 bbee265e630d0db316d1a8314f72d116 525 SMART SM00155 370 397 0.0054 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFR_31470 bbee265e630d0db316d1a8314f72d116 525 SMART SM00155 130 163 160.0 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFR_31470 bbee265e630d0db316d1a8314f72d116 525 Pfam PF13091 PLD-like domain 286 411 1.2E-6 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFR_31470 bbee265e630d0db316d1a8314f72d116 525 SUPERFAMILY SSF56024 274 410 1.92E-20 T 12-10-2018 AFR_31470 bbee265e630d0db316d1a8314f72d116 525 SUPERFAMILY SSF56024 19 262 1.35E-17 T 12-10-2018 AFR_31470 bbee265e630d0db316d1a8314f72d116 525 Gene3D G3DSA:3.30.870.10 270 417 3.1E-14 T 12-10-2018 AFR_31470 bbee265e630d0db316d1a8314f72d116 525 Gene3D G3DSA:3.30.870.10 19 234 1.8E-13 T 12-10-2018 AFR_26965 48840016afbe9686db4a29562d356c81 285 Gene3D G3DSA:3.40.50.12370 148 281 3.6E-23 T 12-10-2018 AFR_26965 48840016afbe9686db4a29562d356c81 285 Pfam PF00582 Universal stress protein family 150 264 1.7E-12 T 12-10-2018 IPR006016 UspA AFR_26965 48840016afbe9686db4a29562d356c81 285 Pfam PF00582 Universal stress protein family 9 140 6.1E-9 T 12-10-2018 IPR006016 UspA AFR_26965 48840016afbe9686db4a29562d356c81 285 SUPERFAMILY SSF52402 149 265 1.59E-19 T 12-10-2018 AFR_26965 48840016afbe9686db4a29562d356c81 285 PRINTS PR01438 Universal stress protein signature 242 264 8.3E-5 T 12-10-2018 IPR006015 Universal stress protein A AFR_26965 48840016afbe9686db4a29562d356c81 285 PRINTS PR01438 Universal stress protein signature 146 164 8.3E-5 T 12-10-2018 IPR006015 Universal stress protein A AFR_26965 48840016afbe9686db4a29562d356c81 285 Gene3D G3DSA:3.40.50.620 1 144 2.5E-26 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_26965 48840016afbe9686db4a29562d356c81 285 SUPERFAMILY SSF52402 8 140 1.42E-16 T 12-10-2018 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 Gene3D G3DSA:3.50.50.60 6 359 2.4E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 6 325 1.0E-57 T 12-10-2018 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 1.2E-8 T 12-10-2018 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 1.2E-8 T 12-10-2018 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.2E-8 T 12-10-2018 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.2E-8 T 12-10-2018 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 SUPERFAMILY SSF51905 137 357 2.37E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 29 51 5.8E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 316 334 5.8E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 176 200 5.8E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 149 5.8E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 SUPERFAMILY SSF51905 4 233 2.36E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37570 962f90a4a0e23c882275be4e59d54d49 521 Gene3D G3DSA:3.50.50.60 152 283 2.4E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_34775 76bff07f0219a104d83d5a5dfb1db050 116 Gene3D G3DSA:1.20.890.50 82 116 3.5E-16 T 12-10-2018 AFR_34775 76bff07f0219a104d83d5a5dfb1db050 116 Pfam PF11774 Lsr2 1 114 1.3E-41 T 12-10-2018 IPR024412 Lsr2 AFR_34775 76bff07f0219a104d83d5a5dfb1db050 116 Gene3D G3DSA:3.30.60.230 1 59 1.1E-23 T 12-10-2018 AFR_34775 76bff07f0219a104d83d5a5dfb1db050 116 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 112 7.0E-20 T 12-10-2018 IPR024412 Lsr2 AFR_33505 e1100e94dca914480ac9bd80c4194d0b 287 Pfam PF12697 Alpha/beta hydrolase family 28 274 5.1E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_33505 e1100e94dca914480ac9bd80c4194d0b 287 Gene3D G3DSA:3.40.50.1820 16 284 1.4E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33505 e1100e94dca914480ac9bd80c4194d0b 287 SUPERFAMILY SSF53474 24 281 9.26E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_10030 b9705852f2b278b887c111d78356e2e1 237 Gene3D G3DSA:3.20.20.10 1 236 6.4E-71 T 12-10-2018 IPR029066 PLP-binding barrel AFR_10030 b9705852f2b278b887c111d78356e2e1 237 SUPERFAMILY SSF51419 4 231 1.01E-61 T 12-10-2018 IPR029066 PLP-binding barrel AFR_10030 b9705852f2b278b887c111d78356e2e1 237 Pfam PF01168 Alanine racemase, N-terminal domain 11 233 2.5E-18 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_10030 b9705852f2b278b887c111d78356e2e1 237 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 79 93 - T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFR_10030 b9705852f2b278b887c111d78356e2e1 237 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 10 232 26.018 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFR_10030 b9705852f2b278b887c111d78356e2e1 237 PIRSF PIRSF004848 2 237 8.5E-62 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFR_10030 b9705852f2b278b887c111d78356e2e1 237 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 10 233 1.3E-40 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 Gene3D G3DSA:3.40.50.300 282 646 3.9E-124 T 12-10-2018 AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 Gene3D G3DSA:1.10.10.160 109 183 2.7E-99 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 1 768 7.3E-291 T 12-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 Pfam PF13361 UvrD-like helicase C-terminal domain 279 628 1.5E-64 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 Gene3D G3DSA:1.10.486.10 385 561 3.9E-124 T 12-10-2018 AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 SUPERFAMILY SSF52540 2 655 2.41E-178 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 Gene3D G3DSA:3.40.50.300 5 276 2.7E-99 T 12-10-2018 AFR_05070 3935d7b4a53f996d3ab33fb6aa8b4189 770 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 273 1.7E-77 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 SUPERFAMILY SSF51445 3 671 2.28E-123 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 Gene3D G3DSA:3.20.20.80 5 671 5.5E-175 T 12-10-2018 AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 SMART SM00642 3 659 2.4E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 Gene3D G3DSA:1.10.10.470 490 580 5.5E-175 T 12-10-2018 AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 Gene3D G3DSA:1.10.150.200 314 446 5.5E-175 T 12-10-2018 AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 Pfam PF00128 Alpha amylase, catalytic domain 25 234 7.0E-16 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 Gene3D G3DSA:3.30.1590.10 89 208 5.5E-175 T 12-10-2018 AFR_31590 2279897f7c6eb75609cd16a76c9b02f6 756 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 3 754 2.2E-256 T 12-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 Gene3D G3DSA:3.40.50.12740 12 221 6.2E-63 T 12-10-2018 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 SUPERFAMILY SSF52172 11 141 1.29E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 3.6E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 SUPERFAMILY SSF46894 151 220 8.84E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 SMART SM00421 158 215 7.4E-27 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.7E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.7E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.7E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 Pfam PF00072 Response regulator receiver domain 14 124 1.1E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_05025 18f9ddbd5d2ecbf3d927a1fa40d17754 221 SMART SM00448 12 123 2.0E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_10070 980a6e5bdc282b1d9a2c158c181e7583 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 131 147 2.9E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFR_10070 980a6e5bdc282b1d9a2c158c181e7583 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 88 103 2.9E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFR_10070 980a6e5bdc282b1d9a2c158c181e7583 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 46 54 2.9E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFR_10070 980a6e5bdc282b1d9a2c158c181e7583 169 ProSitePatterns PS00855 Signal peptidases II signature. 91 103 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFR_10070 980a6e5bdc282b1d9a2c158c181e7583 169 TIGRFAM TIGR00077 lspA: signal peptidase II 3 151 1.7E-26 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFR_10070 980a6e5bdc282b1d9a2c158c181e7583 169 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 156 14.716 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFR_10070 980a6e5bdc282b1d9a2c158c181e7583 169 Pfam PF01252 Signal peptidase (SPase) II 8 148 6.0E-29 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 Pfam PF00175 Oxidoreductase NAD-binding domain 116 223 7.6E-18 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 269 342 3.4E-15 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 57 64 2.8E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 139 148 2.8E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 115 134 2.8E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 151 162 2.8E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 SUPERFAMILY SSF63380 4 106 1.24E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 Pfam PF00970 Oxidoreductase FAD-binding domain 9 104 1.0E-8 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 Gene3D G3DSA:3.40.50.80 109 245 3.9E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 Gene3D G3DSA:2.40.30.10 3 102 2.5E-19 T 12-10-2018 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 6 351 1.9E-138 T 12-10-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 Gene3D G3DSA:3.10.20.30 253 352 2.6E-28 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 PRINTS PR00406 Cytochrome B5 reductase signature 115 134 1.4E-5 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 PRINTS PR00406 Cytochrome B5 reductase signature 92 106 1.4E-5 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 PRINTS PR00406 Cytochrome B5 reductase signature 151 162 1.4E-5 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 SUPERFAMILY SSF54292 233 350 2.36E-28 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 299 307 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_20830 b0a5d4da0bbdd1879953ea270c608c53 352 SUPERFAMILY SSF52343 95 240 7.07E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_18085 22675ecf0d02a33dee534b9369f49721 251 Gene3D G3DSA:1.10.357.10 87 248 4.0E-39 T 12-10-2018 AFR_18085 22675ecf0d02a33dee534b9369f49721 251 SUPERFAMILY SSF46689 25 89 4.99E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_18085 22675ecf0d02a33dee534b9369f49721 251 Gene3D G3DSA:1.10.10.60 7 86 1.5E-23 T 12-10-2018 AFR_18085 22675ecf0d02a33dee534b9369f49721 251 SUPERFAMILY SSF48498 100 249 6.78E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_18085 22675ecf0d02a33dee534b9369f49721 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 79 3.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18085 22675ecf0d02a33dee534b9369f49721 251 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 99 245 6.7E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_26435 d1ed85340d5038790441b27b3d1efb04 315 PIRSF PIRSF017269 14 283 1.6E-84 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 AFR_26435 d1ed85340d5038790441b27b3d1efb04 315 Gene3D G3DSA:3.40.50.150 82 276 4.1E-57 T 12-10-2018 AFR_26435 d1ed85340d5038790441b27b3d1efb04 315 SUPERFAMILY SSF53335 19 271 3.02E-67 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_26435 d1ed85340d5038790441b27b3d1efb04 315 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 85 249 5.5E-20 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 AFR_26435 d1ed85340d5038790441b27b3d1efb04 315 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 17 67 8.9E-29 T 12-10-2018 AFR_26435 d1ed85340d5038790441b27b3d1efb04 315 Gene3D G3DSA:3.10.330.20 15 80 1.5E-24 T 12-10-2018 AFR_40865 304ae0535099fcc01540142f7675fcaa 293 Gene3D G3DSA:3.40.30.10 139 276 5.5E-20 T 12-10-2018 AFR_40865 304ae0535099fcc01540142f7675fcaa 293 SUPERFAMILY SSF52833 141 275 4.66E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_40865 304ae0535099fcc01540142f7675fcaa 293 Pfam PF01638 HxlR-like helix-turn-helix 21 105 1.6E-20 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_40865 304ae0535099fcc01540142f7675fcaa 293 Pfam PF00578 AhpC/TSA family 169 232 1.5E-10 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_40865 304ae0535099fcc01540142f7675fcaa 293 Gene3D G3DSA:1.10.10.10 4 132 1.0E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40865 304ae0535099fcc01540142f7675fcaa 293 SUPERFAMILY SSF46785 9 110 4.09E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16295 2632fff79a04f11372c0184ada5bce49 432 Pfam PF05762 VWA domain containing CoxE-like protein 208 415 1.1E-27 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like AFR_16295 2632fff79a04f11372c0184ada5bce49 432 Gene3D G3DSA:3.40.50.410 262 415 3.7E-5 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_16295 2632fff79a04f11372c0184ada5bce49 432 SUPERFAMILY SSF53300 268 405 1.09E-10 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_27650 1b48c4da21666725a4cf1ec4f395c074 181 SUPERFAMILY SSF46689 3 71 1.32E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_27650 1b48c4da21666725a4cf1ec4f395c074 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27650 1b48c4da21666725a4cf1ec4f395c074 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27650 1b48c4da21666725a4cf1ec4f395c074 181 Gene3D G3DSA:1.10.357.10 1 174 1.2E-24 T 12-10-2018 AFR_27650 1b48c4da21666725a4cf1ec4f395c074 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 8.7E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04215 8e501fd6aaa51b4150b0718ec0ceb281 434 SUPERFAMILY SSF56112 31 146 1.33E-7 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_04215 8e501fd6aaa51b4150b0718ec0ceb281 434 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 25 423 5.5E-110 T 12-10-2018 IPR018721 Protein of unknown function DUF2252 AFR_33855 19ef55b6598cea95d7f3810278a0eaf1 280 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 232 245 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_33855 19ef55b6598cea95d7f3810278a0eaf1 280 SUPERFAMILY SSF53613 3 278 5.14E-55 T 12-10-2018 IPR029056 Ribokinase-like AFR_33855 19ef55b6598cea95d7f3810278a0eaf1 280 Pfam PF00294 pfkB family carbohydrate kinase 27 276 3.2E-35 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_33855 19ef55b6598cea95d7f3810278a0eaf1 280 Gene3D G3DSA:3.40.1190.20 2 280 3.0E-55 T 12-10-2018 IPR029056 Ribokinase-like AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 162 6.4E-58 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 70 3.1E-30 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 78 161 2.7E-33 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 SUPERFAMILY SSF54364 1 72 8.76E-26 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 164 27.421 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 Gene3D G3DSA:3.10.20.80 1 69 2.4E-29 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 Gene3D G3DSA:3.30.110.10 70 164 1.1E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 AFR_30465 cf42ba08d968e881166dbc7b1bc4bc8e 201 SUPERFAMILY SSF55200 79 162 9.55E-31 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 AFR_15595 c090bf58a255454161cd93c31d10f0ac 384 Pfam PF13360 PQQ-like domain 212 308 1.5E-7 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_15595 c090bf58a255454161cd93c31d10f0ac 384 SUPERFAMILY SSF50998 98 368 8.24E-15 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_15595 c090bf58a255454161cd93c31d10f0ac 384 Gene3D G3DSA:2.130.10.10 27 282 2.4E-18 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 SUPERFAMILY SSF64153 4 226 2.75E-43 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 212 458 2.1E-45 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 PIRSF PIRSF017184 1 465 6.3E-93 T 12-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 SUPERFAMILY SSF53613 206 463 1.26E-53 T 12-10-2018 IPR029056 Ribokinase-like AFR_04830 8d213ae30586e69ab2009b941577a03d 465 Pfam PF01256 Carbohydrate kinase 228 445 1.3E-51 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 Gene3D G3DSA:3.40.1190.20 204 464 6.3E-71 T 12-10-2018 IPR029056 Ribokinase-like AFR_04830 8d213ae30586e69ab2009b941577a03d 465 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 404 414 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site AFR_04830 8d213ae30586e69ab2009b941577a03d 465 Gene3D G3DSA:3.40.50.10260 2 197 3.7E-44 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 Pfam PF03853 YjeF-related protein N-terminus 8 171 4.7E-36 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 205 462 17.718 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFR_04830 8d213ae30586e69ab2009b941577a03d 465 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 7 191 5.9E-27 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFR_19315 c070b981dc5ee9ed12901a0a7754a382 265 SMART SM00382 30 206 3.7E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_19315 c070b981dc5ee9ed12901a0a7754a382 265 Pfam PF00005 ABC transporter 21 157 6.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_19315 c070b981dc5ee9ed12901a0a7754a382 265 SUPERFAMILY SSF52540 1 224 5.58E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19315 c070b981dc5ee9ed12901a0a7754a382 265 Gene3D G3DSA:3.40.50.300 1 253 1.2E-66 T 12-10-2018 AFR_19315 c070b981dc5ee9ed12901a0a7754a382 265 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_34335 281ce2bce523581c775ad440caa89695 180 Pfam PF08281 Sigma-70, region 4 121 169 5.6E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_34335 281ce2bce523581c775ad440caa89695 180 SUPERFAMILY SSF88659 112 174 1.16E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_34335 281ce2bce523581c775ad440caa89695 180 SUPERFAMILY SSF88946 11 94 1.53E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34335 281ce2bce523581c775ad440caa89695 180 Pfam PF04542 Sigma-70 region 2 20 85 6.6E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34335 281ce2bce523581c775ad440caa89695 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 173 5.9E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_34335 281ce2bce523581c775ad440caa89695 180 Gene3D G3DSA:1.10.10.10 113 177 3.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34335 281ce2bce523581c775ad440caa89695 180 Gene3D G3DSA:1.10.1740.10 6 82 7.3E-16 T 12-10-2018 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 SUPERFAMILY SSF88659 158 231 1.31E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Gene3D G3DSA:1.10.10.10 158 233 1.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Pfam PF04542 Sigma-70 region 2 85 154 1.6E-21 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 82 306 7.1E-33 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Pfam PF04539 Sigma-70 region 3 164 239 6.9E-22 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 PRINTS PR00046 Major sigma-70 factor signature 257 269 5.1E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 PRINTS PR00046 Major sigma-70 factor signature 109 122 5.1E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 PRINTS PR00046 Major sigma-70 factor signature 133 141 5.1E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 PRINTS PR00046 Major sigma-70 factor signature 278 293 5.1E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 PRINTS PR00046 Major sigma-70 factor signature 293 304 5.1E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Gene3D G3DSA:1.20.120.1810 16 61 3.4E-5 T 12-10-2018 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Gene3D G3DSA:1.20.120.1810 62 154 4.2E-42 T 12-10-2018 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Gene3D G3DSA:1.10.10.10 235 313 4.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 SUPERFAMILY SSF88659 215 310 3.74E-24 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Pfam PF00140 Sigma-70 factor, region 1.2 20 53 9.0E-11 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 Pfam PF04545 Sigma-70, region 4 253 306 9.8E-13 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 278 304 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_07080 43b9f6e92fa7aec5bd701ccec030563a 316 SUPERFAMILY SSF88946 20 155 2.75E-48 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Gene3D G3DSA:3.30.2080.10 646 1118 2.6E-256 T 12-10-2018 AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Pfam PF00754 F5/8 type C domain 74 188 9.2E-11 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 374 1117 4.6E-146 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Pfam PF07971 Glycosyl hydrolase family 92 586 1114 1.5E-155 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Gene3D G3DSA:2.70.98.10 378 715 2.6E-256 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 SUPERFAMILY SSF48208 612 1096 7.48E-18 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Gene3D G3DSA:2.60.120.260 60 197 3.8E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 SUPERFAMILY SSF49785 67 181 1.35E-14 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Gene3D G3DSA:2.60.120.260 1148 1273 3.0E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Gene3D G3DSA:1.20.1050.60 716 809 2.6E-256 T 12-10-2018 AFR_33675 4e7ed0c97848e8b41be5ffbc5fd9163a 1410 Gene3D G3DSA:1.20.1610.10 810 988 2.6E-256 T 12-10-2018 AFR_29855 33c75262afbed888dedf8cadabeeebbd 233 Pfam PF00535 Glycosyl transferase family 2 5 127 3.3E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_29855 33c75262afbed888dedf8cadabeeebbd 233 Gene3D G3DSA:3.90.550.10 1 230 2.5E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_29855 33c75262afbed888dedf8cadabeeebbd 233 SUPERFAMILY SSF53448 4 163 5.06E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 Pfam PF00652 Ricin-type beta-trefoil lectin domain 1783 1906 1.6E-15 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 Gene3D G3DSA:2.80.10.50 1781 1873 1.4E-9 T 12-10-2018 AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 SMART SM00306 2312 2417 5.7E-5 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 SMART SM00458 1776 1909 7.5E-10 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 Gene3D G3DSA:2.180.10.10 1895 2084 7.1E-17 T 12-10-2018 AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 Gene3D G3DSA:2.180.10.10 1453 1780 1.8E-11 T 12-10-2018 AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 SUPERFAMILY SSF51294 2315 2459 1.7E-17 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2003 2084 1.8E-16 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 Gene3D G3DSA:2.170.16.10 2311 2460 2.5E-40 T 12-10-2018 AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 SUPERFAMILY SSF50370 1784 1906 6.3E-21 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1348 1390 0.0021 T 12-10-2018 IPR006530 YD repeat AFR_15820 6b3a30423cf24b101dd51373965d8e37 2583 Pfam PF07591 Pretoxin HINT domain 2323 2460 4.7E-15 T 12-10-2018 AFR_15615 b79a6d48d091bce0693ef6b3db5a8498 314 Gene3D G3DSA:2.60.40.420 21 167 4.6E-36 T 12-10-2018 IPR008972 Cupredoxin AFR_15615 b79a6d48d091bce0693ef6b3db5a8498 314 Gene3D G3DSA:2.60.40.420 170 312 2.2E-38 T 12-10-2018 IPR008972 Cupredoxin AFR_15615 b79a6d48d091bce0693ef6b3db5a8498 314 ProSitePatterns PS00080 Multicopper oxidases signature 2. 269 280 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 AFR_15615 b79a6d48d091bce0693ef6b3db5a8498 314 Pfam PF07732 Multicopper oxidase 55 164 1.7E-11 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 AFR_15615 b79a6d48d091bce0693ef6b3db5a8498 314 SUPERFAMILY SSF49503 175 288 6.11E-22 T 12-10-2018 IPR008972 Cupredoxin AFR_15615 b79a6d48d091bce0693ef6b3db5a8498 314 SUPERFAMILY SSF49503 52 182 1.01E-17 T 12-10-2018 IPR008972 Cupredoxin AFR_15615 b79a6d48d091bce0693ef6b3db5a8498 314 Pfam PF07731 Multicopper oxidase 181 289 2.9E-14 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 AFR_04995 c847827176692ea7951460321c6018ef 301 Pfam PF00293 NUDIX domain 4 120 2.8E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_04995 c847827176692ea7951460321c6018ef 301 Pfam PF00293 NUDIX domain 156 278 5.5E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_04995 c847827176692ea7951460321c6018ef 301 SUPERFAMILY SSF55811 4 126 2.03E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_04995 c847827176692ea7951460321c6018ef 301 Gene3D G3DSA:3.90.79.10 147 299 3.8E-22 T 12-10-2018 AFR_04995 c847827176692ea7951460321c6018ef 301 PRINTS PR00502 NUDIX hydrolase family signature 34 48 1.5E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_04995 c847827176692ea7951460321c6018ef 301 PRINTS PR00502 NUDIX hydrolase family signature 48 63 1.5E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_04995 c847827176692ea7951460321c6018ef 301 ProSitePatterns PS00893 Nudix box signature. 190 211 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_04995 c847827176692ea7951460321c6018ef 301 SUPERFAMILY SSF55811 153 296 9.48E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_04995 c847827176692ea7951460321c6018ef 301 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_04995 c847827176692ea7951460321c6018ef 301 Gene3D G3DSA:3.90.79.10 2 129 1.5E-23 T 12-10-2018 AFR_19135 814549294944707b2536212029b8fc5f 344 Gene3D G3DSA:3.20.20.30 3 343 1.7E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_19135 814549294944707b2536212029b8fc5f 344 Pfam PF00296 Luciferase-like monooxygenase 20 298 5.6E-47 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_19135 814549294944707b2536212029b8fc5f 344 SUPERFAMILY SSF51679 6 339 4.19E-76 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_19135 814549294944707b2536212029b8fc5f 344 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 5 338 4.1E-154 T 12-10-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative AFR_42430 1ba5882ea303a6f3e24f62e755abfa65 403 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 396 2.3E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42430 1ba5882ea303a6f3e24f62e755abfa65 403 Pfam PF06580 Histidine kinase 194 272 1.0E-23 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 AFR_42430 1ba5882ea303a6f3e24f62e755abfa65 403 Gene3D G3DSA:3.30.565.10 250 397 2.7E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_42430 1ba5882ea303a6f3e24f62e755abfa65 403 SMART SM00387 283 398 3.2E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42430 1ba5882ea303a6f3e24f62e755abfa65 403 SUPERFAMILY SSF55874 249 395 2.1E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_04210 217cb0c4b71429cb18b3dfd1d99e8c46 186 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 12 149 8.8E-67 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04210 217cb0c4b71429cb18b3dfd1d99e8c46 186 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 2 148 40.313 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04210 217cb0c4b71429cb18b3dfd1d99e8c46 186 SUPERFAMILY SSF56770 6 150 5.1E-61 T 12-10-2018 AFR_04210 217cb0c4b71429cb18b3dfd1d99e8c46 186 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 34 142 3.0E-23 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04210 217cb0c4b71429cb18b3dfd1d99e8c46 186 Gene3D G3DSA:3.40.50.12280 5 162 2.6E-69 T 12-10-2018 AFR_29070 31f96444395b985ce266746e463c0040 504 Pfam PF00069 Protein kinase domain 2 239 3.0E-41 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_29070 31f96444395b985ce266746e463c0040 504 Gene3D G3DSA:3.30.200.20 1 68 3.3E-10 T 12-10-2018 AFR_29070 31f96444395b985ce266746e463c0040 504 SUPERFAMILY SSF56112 1 240 6.07E-58 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_29070 31f96444395b985ce266746e463c0040 504 Gene3D G3DSA:1.10.510.10 69 266 4.5E-44 T 12-10-2018 AFR_29070 31f96444395b985ce266746e463c0040 504 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 108 120 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_29070 31f96444395b985ce266746e463c0040 504 SMART SM00220 1 243 2.8E-35 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_29070 31f96444395b985ce266746e463c0040 504 PIRSF PIRSF000654 9 246 3.6E-20 T 12-10-2018 AFR_29070 31f96444395b985ce266746e463c0040 504 Gene3D G3DSA:2.60.120.560 350 500 1.1E-6 T 12-10-2018 AFR_03745 864702ad74c037d50941a73a244e572e 540 Gene3D G3DSA:3.40.50.300 323 531 1.2E-34 T 12-10-2018 AFR_03745 864702ad74c037d50941a73a244e572e 540 Pfam PF00664 ABC transporter transmembrane region 24 277 5.4E-17 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_03745 864702ad74c037d50941a73a244e572e 540 Gene3D G3DSA:1.20.1560.10 1 310 5.2E-43 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_03745 864702ad74c037d50941a73a244e572e 540 SUPERFAMILY SSF52540 332 532 5.73E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03745 864702ad74c037d50941a73a244e572e 540 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_03745 864702ad74c037d50941a73a244e572e 540 Pfam PF00005 ABC transporter 364 464 2.3E-9 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03745 864702ad74c037d50941a73a244e572e 540 SUPERFAMILY SSF90123 2 308 9.29E-46 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_14000 a0796dff6a09ee69bc7c8b4b2fe15ebf 220 Gene3D G3DSA:3.40.50.300 1 218 3.4E-60 T 12-10-2018 AFR_14000 a0796dff6a09ee69bc7c8b4b2fe15ebf 220 SMART SM00382 26 215 2.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_14000 a0796dff6a09ee69bc7c8b4b2fe15ebf 220 Pfam PF00005 ABC transporter 17 165 2.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_14000 a0796dff6a09ee69bc7c8b4b2fe15ebf 220 SUPERFAMILY SSF52540 2 212 3.99E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25860 a69a25459ef34212f724aee80c017260 472 Gene3D G3DSA:3.40.50.300 38 237 1.3E-18 T 12-10-2018 AFR_25860 a69a25459ef34212f724aee80c017260 472 Pfam PF00350 Dynamin family 38 144 2.5E-10 T 12-10-2018 IPR022812 Dynamin superfamily AFR_25860 a69a25459ef34212f724aee80c017260 472 SUPERFAMILY SSF52540 31 220 7.55E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15490 7b1e60917fc10ba801ca502e43866fe1 957 SUPERFAMILY SSF48208 268 738 5.61E-21 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_15490 7b1e60917fc10ba801ca502e43866fe1 957 Pfam PF07971 Glycosyl hydrolase family 92 234 752 1.5E-148 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_15490 7b1e60917fc10ba801ca502e43866fe1 957 Gene3D G3DSA:3.30.2080.10 294 754 6.3E-241 T 12-10-2018 AFR_15490 7b1e60917fc10ba801ca502e43866fe1 957 Gene3D G3DSA:1.20.1610.10 444 624 6.3E-241 T 12-10-2018 AFR_15490 7b1e60917fc10ba801ca502e43866fe1 957 Gene3D G3DSA:2.70.98.10 26 346 6.3E-241 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_15490 7b1e60917fc10ba801ca502e43866fe1 957 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 16 753 5.9E-158 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_15490 7b1e60917fc10ba801ca502e43866fe1 957 Gene3D G3DSA:1.20.1050.60 347 443 6.3E-241 T 12-10-2018 AFR_40695 f89fd1d71d06b36f4538b7126aaa771d 246 Pfam PF01063 Amino-transferase class IV 10 223 6.6E-44 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFR_40695 f89fd1d71d06b36f4538b7126aaa771d 246 Gene3D G3DSA:3.30.470.10 1 86 1.4E-21 T 12-10-2018 AFR_40695 f89fd1d71d06b36f4538b7126aaa771d 246 Gene3D G3DSA:3.20.10.10 90 243 5.0E-43 T 12-10-2018 AFR_40695 f89fd1d71d06b36f4538b7126aaa771d 246 SUPERFAMILY SSF56752 2 242 5.62E-54 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFR_19605 757d8d268aef97809519389b64be6221 482 SUPERFAMILY SSF55103 220 466 3.27E-69 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFR_19605 757d8d268aef97809519389b64be6221 482 Gene3D G3DSA:1.10.45.10 418 458 1.2E-8 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFR_19605 757d8d268aef97809519389b64be6221 482 Gene3D G3DSA:3.30.465.40 15 236 5.0E-62 T 12-10-2018 AFR_19605 757d8d268aef97809519389b64be6221 482 SUPERFAMILY SSF56176 6 217 1.03E-65 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_19605 757d8d268aef97809519389b64be6221 482 Gene3D G3DSA:3.30.70.2740 336 417 3.5E-10 T 12-10-2018 AFR_19605 757d8d268aef97809519389b64be6221 482 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 457 1.4E-67 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFR_19605 757d8d268aef97809519389b64be6221 482 Pfam PF01565 FAD binding domain 42 180 8.0E-36 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_03060 14f75595c562962dcec21f9bda662e27 463 Gene3D G3DSA:3.50.50.60 139 221 1.2E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_03060 14f75595c562962dcec21f9bda662e27 463 SUPERFAMILY SSF51905 1 363 2.59E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_03060 14f75595c562962dcec21f9bda662e27 463 Gene3D G3DSA:3.50.50.60 288 441 5.4E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_03060 14f75595c562962dcec21f9bda662e27 463 Pfam PF00743 Flavin-binding monooxygenase-like 66 203 7.7E-12 T 12-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 AFR_03060 14f75595c562962dcec21f9bda662e27 463 Gene3D G3DSA:3.50.50.60 1 138 3.9E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_35370 8cc77c826fe6448d0695a98b55e42887 188 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 3 187 2.3E-81 T 12-10-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD AFR_35370 8cc77c826fe6448d0695a98b55e42887 188 SUPERFAMILY SSF48150 13 139 3.49E-11 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_35370 8cc77c826fe6448d0695a98b55e42887 188 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 24 181 6.4E-12 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_25560 9a84d620045ef77c9000de2da62fd7d2 462 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 64 450 4.3E-138 T 12-10-2018 IPR018721 Protein of unknown function DUF2252 AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 SUPERFAMILY SSF111369 64 231 9.29E-12 T 12-10-2018 AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 Gene3D G3DSA:2.40.50.100 72 105 6.1E-15 T 12-10-2018 AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 Gene3D G3DSA:2.40.420.20 291 358 3.0E-7 T 12-10-2018 AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 48 353 4.9E-33 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 256 1.3E-9 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 Gene3D G3DSA:2.40.30.170 182 290 3.4E-19 T 12-10-2018 AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 Gene3D G3DSA:2.40.30.170 61 71 6.1E-15 T 12-10-2018 AFR_20575 3e54ae5ddd3cc15797dc581b332bac97 390 Gene3D G3DSA:1.10.287.470 106 133 6.1E-15 T 12-10-2018 AFR_14965 4042498cc3384d21155044d78640a2cf 643 Pfam PF16116 Domain of unknown function (DUF4832) 369 501 3.8E-9 T 12-10-2018 IPR032267 Domain of unknown function DUF4832 AFR_14965 4042498cc3384d21155044d78640a2cf 643 Gene3D G3DSA:2.60.120.260 519 643 3.1E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_14965 4042498cc3384d21155044d78640a2cf 643 SUPERFAMILY SSF49785 530 642 5.95E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_14965 4042498cc3384d21155044d78640a2cf 643 Gene3D G3DSA:3.20.20.80 91 242 8.7E-9 T 12-10-2018 AFR_00880 22941b5e18c08516140aeb3adc932ea6 196 PIRSF PIRSF018427 2 191 1.4E-45 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 AFR_00880 22941b5e18c08516140aeb3adc932ea6 196 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 8 183 29.841 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 AFR_00880 22941b5e18c08516140aeb3adc932ea6 196 Pfam PF00293 NUDIX domain 35 168 2.1E-24 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_00880 22941b5e18c08516140aeb3adc932ea6 196 SUPERFAMILY SSF55811 10 176 3.79E-39 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_00880 22941b5e18c08516140aeb3adc932ea6 196 Gene3D G3DSA:3.90.79.10 2 187 7.6E-44 T 12-10-2018 AFR_00880 22941b5e18c08516140aeb3adc932ea6 196 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 12 168 3.5E-33 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 AFR_07665 009ead1061994125cf6cb9640a57a740 244 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 217 2.9E-56 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 AFR_07665 009ead1061994125cf6cb9640a57a740 244 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 193 1.1E-49 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 AFR_25955 758470530cb9ff81f219e0cbd9bfe234 348 Pfam PF00534 Glycosyl transferases group 1 176 322 4.2E-21 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_25955 758470530cb9ff81f219e0cbd9bfe234 348 Gene3D G3DSA:3.40.50.2000 12 345 2.8E-56 T 12-10-2018 AFR_25955 758470530cb9ff81f219e0cbd9bfe234 348 TIGRFAM TIGR04047 MSMEG_0565_glyc: glycosyltransferase, MSMEG_0565 family 2 346 4.6E-136 T 12-10-2018 IPR023986 Glycosyltransferase, putative, MSMEG0565 family AFR_25955 758470530cb9ff81f219e0cbd9bfe234 348 SUPERFAMILY SSF53756 3 348 5.83E-60 T 12-10-2018 AFR_25955 758470530cb9ff81f219e0cbd9bfe234 348 Pfam PF13439 Glycosyltransferase Family 4 14 163 4.7E-21 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_25955 758470530cb9ff81f219e0cbd9bfe234 348 Gene3D G3DSA:3.40.50.2000 160 332 2.8E-56 T 12-10-2018 AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 Pfam PF01047 MarR family 36 94 2.1E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 SUPERFAMILY SSF46785 9 141 3.76E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 7.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 7.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 7.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 7.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 Gene3D G3DSA:1.10.10.10 3 142 4.0E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 SMART SM00347 29 129 7.5E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29745 dadd3696bcb90b03c0b30ba0de6190cd 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_36765 a551eea730a74ede2a3ca532bbaa1f4d 298 Gene3D G3DSA:1.10.10.10 1 90 3.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36765 a551eea730a74ede2a3ca532bbaa1f4d 298 Gene3D G3DSA:3.40.190.10 92 280 5.2E-29 T 12-10-2018 AFR_36765 a551eea730a74ede2a3ca532bbaa1f4d 298 SUPERFAMILY SSF53850 89 295 1.1E-28 T 12-10-2018 AFR_36765 a551eea730a74ede2a3ca532bbaa1f4d 298 SUPERFAMILY SSF46785 1 111 5.84E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_36765 a551eea730a74ede2a3ca532bbaa1f4d 298 Gene3D G3DSA:3.40.190.10 170 268 5.2E-29 T 12-10-2018 AFR_36765 a551eea730a74ede2a3ca532bbaa1f4d 298 Pfam PF03466 LysR substrate binding domain 89 293 6.9E-31 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_36765 a551eea730a74ede2a3ca532bbaa1f4d 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.4E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 60 93 0.0073 T 12-10-2018 IPR004176 Clp, N-terminal AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 123 166 3.8E-5 T 12-10-2018 IPR004176 Clp, N-terminal AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 233 366 1.2E-12 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 SMART SM01086 740 829 2.9E-36 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Gene3D G3DSA:3.40.50.300 375 490 2.7E-39 T 12-10-2018 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Gene3D G3DSA:1.10.1780.10 19 170 2.1E-20 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 740 820 2.2E-25 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 SUPERFAMILY SSF52540 189 459 1.17E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Gene3D G3DSA:1.10.8.60 740 834 7.6E-28 T 12-10-2018 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Gene3D G3DSA:3.40.50.300 180 374 4.6E-69 T 12-10-2018 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 612 630 5.9E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 641 659 5.9E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 567 585 5.9E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 674 688 5.9E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 597 615 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 SUPERFAMILY SSF52540 512 829 3.85E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 SUPERFAMILY SSF81923 32 165 6.02E-12 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Gene3D G3DSA:3.40.50.300 494 738 5.6E-97 T 12-10-2018 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 SMART SM00382 563 741 2.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 SMART SM00382 228 375 3.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Pfam PF02151 UvrB/uvrC motif 448 483 4.4E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 Pfam PF07724 AAA domain (Cdc48 subfamily) 562 734 2.7E-54 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_26695 7e193a389f7b394e7bd54b0496aa6760 839 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 326 338 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 Gene3D G3DSA:3.10.450.50 188 303 8.2E-18 T 12-10-2018 AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 14 308 3.2E-90 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 Gene3D G3DSA:1.10.1740.10 1 102 1.2E-26 T 12-10-2018 AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 Gene3D G3DSA:1.10.10.10 128 184 5.0E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 SUPERFAMILY SSF88946 1 93 9.16E-25 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 SUPERFAMILY SSF88659 128 182 2.06E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 SUPERFAMILY SSF54427 190 299 5.66E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 Pfam PF04542 Sigma-70 region 2 21 87 8.5E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 Pfam PF12680 SnoaL-like domain 199 294 3.7E-12 T 12-10-2018 IPR037401 SnoaL-like domain AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 Pfam PF08281 Sigma-70, region 4 129 178 1.3E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_38635 e70b925660f9928d358df7a30dd52e3f 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 182 2.7E-16 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_12875 c306d951576c816c721466a16c96aa02 366 SUPERFAMILY SSF47203 209 362 5.33E-11 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_12875 c306d951576c816c721466a16c96aa02 366 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 219 339 3.3E-12 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFR_12875 c306d951576c816c721466a16c96aa02 366 Gene3D G3DSA:2.40.110.10 107 196 2.3E-24 T 12-10-2018 AFR_12875 c306d951576c816c721466a16c96aa02 366 PIRSF PIRSF016578 3 366 7.4E-68 T 12-10-2018 AFR_12875 c306d951576c816c721466a16c96aa02 366 SUPERFAMILY SSF56645 8 193 3.93E-30 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_12875 c306d951576c816c721466a16c96aa02 366 Gene3D G3DSA:1.20.140.10 197 362 8.5E-22 T 12-10-2018 AFR_12875 c306d951576c816c721466a16c96aa02 366 Gene3D G3DSA:1.10.540.10 3 102 2.1E-17 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 Gene3D G3DSA:2.170.120.20 100 188 7.7E-14 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 SUPERFAMILY SSF50715 4 187 2.09E-46 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 Gene3D G3DSA:2.40.240.10 2 97 1.5E-25 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 182 24.249 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 179 1.1E-40 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 102 181 1.3E-15 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 Pfam PF01386 Ribosomal L25p family 6 94 1.3E-25 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFR_39715 c743a4a3d245f31249fe788124ea15a1 210 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 97 2.0E-15 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 Gene3D G3DSA:1.10.10.10 2 162 2.4E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 SUPERFAMILY SSF46785 7 160 7.04E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 7.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 89 7.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 7.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 7.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 SMART SM00347 46 149 1.5E-24 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32180 ae06e7b93094bc9d0e093fa3f5a9adce 163 Pfam PF12802 MarR family 52 113 9.5E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_14135 6e04d27283f78a17530f0062042d2edc 401 Gene3D G3DSA:3.60.40.10 166 392 7.0E-42 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_14135 6e04d27283f78a17530f0062042d2edc 401 SUPERFAMILY SSF81606 184 389 1.96E-13 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_14135 6e04d27283f78a17530f0062042d2edc 401 SUPERFAMILY SSF55781 20 139 4.58E-7 T 12-10-2018 AFR_14135 6e04d27283f78a17530f0062042d2edc 401 Gene3D G3DSA:3.30.450.40 21 148 3.3E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_14135 6e04d27283f78a17530f0062042d2edc 401 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 390 9.5E-35 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_14135 6e04d27283f78a17530f0062042d2edc 401 SMART SM00331 170 390 4.8E-23 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 SMART SM00895 94 220 2.7E-14 T 12-10-2018 IPR011711 GntR, C-terminal AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 Pfam PF07729 FCD domain 94 217 4.5E-22 T 12-10-2018 IPR011711 GntR, C-terminal AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 Gene3D G3DSA:1.20.120.530 88 225 8.5E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 SMART SM00345 8 69 1.5E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 Gene3D G3DSA:1.10.10.10 2 73 4.8E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 SUPERFAMILY SSF48008 91 223 1.46E-19 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 SUPERFAMILY SSF46785 3 73 2.31E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_28675 5457d010edcb5e6a6fbc9a87e103fb2b 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 63 9.2E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_20845 257aaf3f1a027fdcddb9f97c3d28ecd6 326 SUPERFAMILY SSF51430 1 313 1.96E-94 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_20845 257aaf3f1a027fdcddb9f97c3d28ecd6 326 Pfam PF00248 Aldo/keto reductase family 15 310 7.8E-71 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_20845 257aaf3f1a027fdcddb9f97c3d28ecd6 326 Gene3D G3DSA:3.20.20.100 1 316 2.2E-105 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_11650 667e835735e50adb76922e1a45f879dd 205 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 93 6.5E-14 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_11650 667e835735e50adb76922e1a45f879dd 205 SUPERFAMILY SSF51735 4 187 5.55E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11650 667e835735e50adb76922e1a45f879dd 205 Gene3D G3DSA:3.40.50.720 1 191 1.2E-40 T 12-10-2018 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 Gene3D G3DSA:1.10.10.10 783 902 6.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 SUPERFAMILY SSF46894 836 895 1.53E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 Pfam PF00196 Bacterial regulatory proteins, luxR family 844 896 2.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 845 859 1.6E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 887 1.6E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 875 1.6E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 SMART SM00421 842 899 5.1E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 Pfam PF13191 AAA ATPase domain 3 139 2.3E-16 T 12-10-2018 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 Gene3D G3DSA:1.25.40.10 469 771 1.0E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 Gene3D G3DSA:3.40.50.300 1 157 5.5E-7 T 12-10-2018 AFR_34165 e88c3298020d8a35ead0f86f0ecbaf7e 902 SUPERFAMILY SSF52540 2 222 1.68E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32065 51fc265f68c678777ad45472f97c113e 449 SMART SM00304 170 222 1.3E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_32065 51fc265f68c678777ad45472f97c113e 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 446 6.4E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_32065 51fc265f68c678777ad45472f97c113e 449 SUPERFAMILY SSF158472 170 217 1.96E-5 T 12-10-2018 AFR_32065 51fc265f68c678777ad45472f97c113e 449 SUPERFAMILY SSF47384 207 289 5.49E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_32065 51fc265f68c678777ad45472f97c113e 449 SUPERFAMILY SSF55874 278 445 3.01E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32065 51fc265f68c678777ad45472f97c113e 449 Gene3D G3DSA:1.10.287.130 174 290 1.8E-24 T 12-10-2018 AFR_32065 51fc265f68c678777ad45472f97c113e 449 Gene3D G3DSA:3.30.565.10 294 448 1.6E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32065 51fc265f68c678777ad45472f97c113e 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 288 3.3E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_32065 51fc265f68c678777ad45472f97c113e 449 SMART SM00388 223 289 6.6E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_32065 51fc265f68c678777ad45472f97c113e 449 SMART SM00387 335 447 7.9E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_05650 802cae8106b977769f174201e10e5fd7 319 SUPERFAMILY SSF142338 3 316 1.83E-76 T 12-10-2018 AFR_05650 802cae8106b977769f174201e10e5fd7 319 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 311 4.4E-116 T 12-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 AFR_05650 802cae8106b977769f174201e10e5fd7 319 Gene3D G3DSA:1.10.8.240 39 127 2.6E-93 T 12-10-2018 AFR_05650 802cae8106b977769f174201e10e5fd7 319 Pfam PF01933 Uncharacterised protein family UPF0052 3 283 1.4E-61 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 AFR_05650 802cae8106b977769f174201e10e5fd7 319 Gene3D G3DSA:3.40.50.10680 7 284 2.6E-93 T 12-10-2018 AFR_05650 802cae8106b977769f174201e10e5fd7 319 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 319 127.054 T 12-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 SUPERFAMILY SSF46785 5 88 2.39E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 Pfam PF03466 LysR substrate binding domain 89 276 2.7E-17 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 Gene3D G3DSA:1.10.10.10 1 89 2.8E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 SUPERFAMILY SSF53850 90 282 1.71E-21 T 12-10-2018 AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.6E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 Gene3D G3DSA:3.40.190.10 166 253 4.8E-21 T 12-10-2018 AFR_35580 573d73ea3d4757c0107c65aaa42f16d2 300 Gene3D G3DSA:3.40.190.10 106 273 4.8E-21 T 12-10-2018 AFR_42270 0dbdf323c1fcf6003ed5d2edbbe992bd 105 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 1.7E-21 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_42270 0dbdf323c1fcf6003ed5d2edbbe992bd 105 SUPERFAMILY SSF46785 6 92 7.89E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_42270 0dbdf323c1fcf6003ed5d2edbbe992bd 105 Gene3D G3DSA:1.10.10.10 2 96 6.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 Pfam PF03704 Bacterial transcriptional activator domain 100 245 3.8E-41 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 Gene3D G3DSA:1.10.10.10 1 97 9.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 Gene3D G3DSA:1.25.40.10 98 262 1.1E-47 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 SUPERFAMILY SSF46894 6 95 3.97E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 95 1.6E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 SUPERFAMILY SSF48452 97 264 7.15E-37 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 SUPERFAMILY SSF52540 254 468 1.16E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 SMART SM01043 100 245 1.1E-47 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 SMART SM00862 18 95 1.3E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 Gene3D G3DSA:3.40.50.300 266 452 9.7E-7 T 12-10-2018 AFR_06620 3de2ee989f5692f3875176a858b0089f 1013 Pfam PF13191 AAA ATPase domain 263 323 8.6E-11 T 12-10-2018 AFR_42975 9547601220de93ff8731668191615e92 236 Gene3D G3DSA:3.40.50.150 2 215 1.7E-53 T 12-10-2018 AFR_42975 9547601220de93ff8731668191615e92 236 Pfam PF02527 rRNA small subunit methyltransferase G 8 179 7.8E-45 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFR_42975 9547601220de93ff8731668191615e92 236 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 11 176 1.1E-33 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFR_42975 9547601220de93ff8731668191615e92 236 SUPERFAMILY SSF53335 9 198 1.99E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_42975 9547601220de93ff8731668191615e92 236 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 1 204 23.231 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 4 143 38.416 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 Gene3D G3DSA:1.10.10.10 61 144 1.8E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 64 142 4.3E-32 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 Gene3D G3DSA:3.30.160.70 3 57 3.4E-7 T 12-10-2018 AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 64 142 5.8E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 SUPERFAMILY SSF53155 3 62 5.1E-8 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 113 119 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFR_42885 00b3bcdecf08826d97435de8925fbfe1 152 SUPERFAMILY SSF46767 62 142 6.28E-31 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AFR_05155 34c1ccfc08cc41f6734b50bc8b4b311b 304 SUPERFAMILY SSF53448 1 215 6.38E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05155 34c1ccfc08cc41f6734b50bc8b4b311b 304 Pfam PF00535 Glycosyl transferase family 2 8 162 4.5E-21 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_05155 34c1ccfc08cc41f6734b50bc8b4b311b 304 Gene3D G3DSA:3.90.550.10 1 212 1.3E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_13345 f924c9a45dfc02f685e1134b4861bc30 271 Pfam PF13560 Helix-turn-helix domain 9 88 2.3E-17 T 12-10-2018 AFR_13345 f924c9a45dfc02f685e1134b4861bc30 271 SMART SM00530 13 85 8.8E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_13345 f924c9a45dfc02f685e1134b4861bc30 271 SUPERFAMILY SSF47413 32 83 4.74E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_13345 f924c9a45dfc02f685e1134b4861bc30 271 Gene3D G3DSA:3.30.450.180 104 261 5.3E-8 T 12-10-2018 AFR_13345 f924c9a45dfc02f685e1134b4861bc30 271 Gene3D G3DSA:1.10.260.40 6 90 2.8E-9 T 12-10-2018 AFR_42895 5b9a5b58316f16590576f275cbd0630b 358 Pfam PF07676 WD40-like Beta Propeller Repeat 173 184 0.078 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_42895 5b9a5b58316f16590576f275cbd0630b 358 SUPERFAMILY SSF82171 135 343 1.96E-18 T 12-10-2018 AFR_42895 5b9a5b58316f16590576f275cbd0630b 358 Gene3D G3DSA:2.120.10.30 169 322 6.5E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_16265 5885017ba70482aeb631ba1a82c71d9d 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 73 2.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_16265 5885017ba70482aeb631ba1a82c71d9d 236 Gene3D G3DSA:1.10.357.10 9 236 8.7E-64 T 12-10-2018 AFR_16265 5885017ba70482aeb631ba1a82c71d9d 236 SUPERFAMILY SSF46689 24 85 1.74E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_16265 5885017ba70482aeb631ba1a82c71d9d 236 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 91 229 6.4E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_16265 5885017ba70482aeb631ba1a82c71d9d 236 SUPERFAMILY SSF48498 94 231 5.67E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 SMART SM00382 286 480 2.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 SMART SM00382 28 225 9.9E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 Gene3D G3DSA:3.40.50.300 1 243 2.6E-58 T 12-10-2018 AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 Gene3D G3DSA:3.40.50.300 253 504 4.8E-51 T 12-10-2018 AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 Pfam PF00005 ABC transporter 19 169 1.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 SUPERFAMILY SSF52540 3 227 1.07E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 SUPERFAMILY SSF52540 272 485 9.92E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02445 feda24c3a9192ab0f8025d8cf78b1bd2 511 Pfam PF00005 ABC transporter 277 431 1.1E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 PRINTS PR00142 RecA protein signature 212 240 5.6E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 PRINTS PR00142 RecA protein signature 299 316 5.6E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 PRINTS PR00142 RecA protein signature 95 124 5.6E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 PRINTS PR00142 RecA protein signature 129 158 5.6E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 PRINTS PR00142 RecA protein signature 167 196 5.6E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 PRINTS PR00142 RecA protein signature 245 274 5.6E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 ProSitePatterns PS00321 recA signature. 215 223 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 SMART SM00382 59 230 6.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_35655 06d4d78b1490e541be58e6d50e311688 348 Pfam PF00154 recA bacterial DNA recombination protein 9 270 2.9E-143 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 Gene3D G3DSA:3.30.250.10 270 348 1.2E-29 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFR_35655 06d4d78b1490e541be58e6d50e311688 348 SUPERFAMILY SSF54752 270 328 6.67E-21 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFR_35655 06d4d78b1490e541be58e6d50e311688 348 Gene3D G3DSA:3.40.50.300 28 269 1.1E-82 T 12-10-2018 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 Hamap MF_00268 Protein RecA [recA]. 7 331 52.856 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 325 8.5E-174 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFR_35655 06d4d78b1490e541be58e6d50e311688 348 SUPERFAMILY SSF52540 6 269 1.11E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40410 35ec483a42f0d5e3dcd12a70d7f54e4f 123 TIGRFAM TIGR00208 fliS: flagellar protein FliS 5 115 2.2E-22 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 AFR_40410 35ec483a42f0d5e3dcd12a70d7f54e4f 123 Pfam PF02561 Flagellar protein FliS 4 114 8.2E-32 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 AFR_40410 35ec483a42f0d5e3dcd12a70d7f54e4f 123 Gene3D G3DSA:1.20.120.340 1 118 3.2E-30 T 12-10-2018 AFR_40410 35ec483a42f0d5e3dcd12a70d7f54e4f 123 PIRSF PIRSF039090 2 122 2.3E-24 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 AFR_40410 35ec483a42f0d5e3dcd12a70d7f54e4f 123 SUPERFAMILY SSF101116 3 114 9.94E-29 T 12-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 AFR_19415 c03c31ef4b18c702ef018a1a139fabcb 111 Gene3D G3DSA:1.10.10.10 3 110 1.5E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19415 c03c31ef4b18c702ef018a1a139fabcb 111 SUPERFAMILY SSF46785 11 100 2.37E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19415 c03c31ef4b18c702ef018a1a139fabcb 111 Pfam PF03551 Transcriptional regulator PadR-like family 25 88 1.1E-16 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_13835 185366a1c7608104ec222008f8954c81 338 Gene3D G3DSA:3.40.50.1820 14 336 1.8E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13835 185366a1c7608104ec222008f8954c81 338 SUPERFAMILY SSF53474 14 334 4.09E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13835 185366a1c7608104ec222008f8954c81 338 Pfam PF00561 alpha/beta hydrolase fold 29 321 1.4E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13835 185366a1c7608104ec222008f8954c81 338 PRINTS PR00412 Epoxide hydrolase signature 55 70 6.6E-18 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13835 185366a1c7608104ec222008f8954c81 338 PRINTS PR00412 Epoxide hydrolase signature 310 332 6.6E-18 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13835 185366a1c7608104ec222008f8954c81 338 PRINTS PR00412 Epoxide hydrolase signature 35 53 6.6E-18 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13835 185366a1c7608104ec222008f8954c81 338 PRINTS PR00412 Epoxide hydrolase signature 101 114 6.6E-18 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13835 185366a1c7608104ec222008f8954c81 338 PRINTS PR00412 Epoxide hydrolase signature 275 291 6.6E-18 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_13835 185366a1c7608104ec222008f8954c81 338 PRINTS PR00412 Epoxide hydrolase signature 115 128 6.6E-18 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_27190 937030f17a39708d9f15ddc09f68de4c 196 Pfam PF12804 MobA-like NTP transferase domain 5 161 1.8E-26 T 12-10-2018 IPR025877 MobA-like NTP transferase AFR_27190 937030f17a39708d9f15ddc09f68de4c 196 SUPERFAMILY SSF53448 3 186 7.98E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_27190 937030f17a39708d9f15ddc09f68de4c 196 Gene3D G3DSA:3.90.550.10 2 191 3.5E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 SUPERFAMILY SSF46955 10 113 7.69E-21 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 SUPERFAMILY SSF55136 123 270 1.64E-11 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 SMART SM00871 121 270 1.1E-13 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 Gene3D G3DSA:3.20.80.10 122 270 1.2E-23 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 Pfam PF06445 GyrI-like small molecule binding domain 123 269 1.8E-10 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 SMART SM00422 10 80 4.7E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 Gene3D G3DSA:1.10.1660.10 7 121 9.6E-22 T 12-10-2018 AFR_14170 402bf13868f613dcb89703e239e4f0e4 275 Pfam PF13411 MerR HTH family regulatory protein 11 77 5.3E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 19 435 1.6E-188 T 12-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 PIRSF PIRSF500824 7 442 1.0E-196 T 12-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 27 433 39.03 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 83 420 3.8E-41 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 Gene3D G3DSA:3.40.50.1100 20 244 1.8E-168 T 12-10-2018 AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 SUPERFAMILY SSF53686 33 431 9.56E-106 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 Gene3D G3DSA:3.40.50.1100 19 426 1.8E-168 T 12-10-2018 AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 111 125 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_16135 e6cddca0a522453eccf01b79e00f89a2 459 PIRSF PIRSF001413 15 439 5.4E-116 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_04115 590cf6317705b8922a3c960fd9247500 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 38 1.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04115 590cf6317705b8922a3c960fd9247500 186 SUPERFAMILY SSF48498 58 170 1.82E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_04115 590cf6317705b8922a3c960fd9247500 186 SUPERFAMILY SSF46689 2 62 2.54E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_04115 590cf6317705b8922a3c960fd9247500 186 Gene3D G3DSA:1.10.357.10 1 176 3.2E-40 T 12-10-2018 AFR_07855 87f1e9df77542faf379831211142feb0 314 Gene3D G3DSA:1.10.3470.10 1 313 5.8E-89 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_07855 87f1e9df77542faf379831211142feb0 314 SUPERFAMILY SSF81345 2 308 2.22E-73 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_07855 87f1e9df77542faf379831211142feb0 314 Pfam PF01032 FecCD transport family 2 308 2.5E-88 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_14705 98ac3d46268998c1946790e931cc63e4 210 SUPERFAMILY SSF48498 95 196 3.26E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_14705 98ac3d46268998c1946790e931cc63e4 210 Gene3D G3DSA:1.10.357.10 9 208 8.1E-44 T 12-10-2018 AFR_14705 98ac3d46268998c1946790e931cc63e4 210 Pfam PF13305 WHG domain 99 183 1.1E-12 T 12-10-2018 IPR025996 WHG domain AFR_14705 98ac3d46268998c1946790e931cc63e4 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 4.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14705 98ac3d46268998c1946790e931cc63e4 210 SUPERFAMILY SSF46689 11 91 2.89E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_05185 743776435e9ec496b001da481179b701 521 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 366 502 6.2E-11 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AFR_05185 743776435e9ec496b001da481179b701 521 Pfam PF01943 Polysaccharide biosynthesis protein 20 312 6.2E-7 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFR_33595 87563ba0d313753bf7863154ed893de8 924 Pfam PF13191 AAA ATPase domain 8 159 3.4E-16 T 12-10-2018 AFR_33595 87563ba0d313753bf7863154ed893de8 924 Gene3D G3DSA:1.10.10.10 836 914 1.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33595 87563ba0d313753bf7863154ed893de8 924 SUPERFAMILY SSF46894 851 913 6.46E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_33595 87563ba0d313753bf7863154ed893de8 924 SMART SM00421 855 912 1.7E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33595 87563ba0d313753bf7863154ed893de8 924 SUPERFAMILY SSF52540 8 175 7.54E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33595 87563ba0d313753bf7863154ed893de8 924 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 900 3.1E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33595 87563ba0d313753bf7863154ed893de8 924 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 872 888 3.1E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33595 87563ba0d313753bf7863154ed893de8 924 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 858 872 3.1E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33595 87563ba0d313753bf7863154ed893de8 924 SUPERFAMILY SSF48452 539 719 6.17E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33595 87563ba0d313753bf7863154ed893de8 924 Gene3D G3DSA:1.25.40.10 528 835 1.5E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33595 87563ba0d313753bf7863154ed893de8 924 Pfam PF00196 Bacterial regulatory proteins, luxR family 857 912 2.5E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_08195 b674d84ed90fbb44b42a7491a10a5ff8 371 Pfam PF03631 Virulence factor BrkB 82 336 1.1E-67 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_08195 b674d84ed90fbb44b42a7491a10a5ff8 371 PIRSF PIRSF035875 57 357 1.6E-89 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_08195 b674d84ed90fbb44b42a7491a10a5ff8 371 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 74 334 3.4E-37 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 SMART SM00421 151 208 1.1E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 Pfam PF00072 Response regulator receiver domain 7 118 3.9E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 SUPERFAMILY SSF46894 138 213 3.27E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 SUPERFAMILY SSF52172 4 135 3.13E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 4.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 4.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 4.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 4.1E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 SMART SM00448 5 118 1.2E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_06710 88f26fa0da09f6740f28ac95c3b5eb94 214 Gene3D G3DSA:3.40.50.12740 5 213 2.5E-67 T 12-10-2018 AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 48 307 49.366 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 80 107 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 49 304 1.3E-73 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 Gene3D G3DSA:3.40.50.150 25 240 5.6E-60 T 12-10-2018 AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 Gene3D G3DSA:1.10.8.100 243 308 1.1E-18 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 SUPERFAMILY SSF53335 48 305 1.76E-64 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 SMART SM00650 64 237 6.1E-67 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AFR_39800 91d24c4bdc960a00a8c330b725d3c2d0 327 Pfam PF00398 Ribosomal RNA adenine dimethylase 52 303 2.0E-42 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AFR_33860 44fc9d34193fe77c04b0bed253895a0b 281 SUPERFAMILY SSF51569 6 270 5.49E-40 T 12-10-2018 AFR_33860 44fc9d34193fe77c04b0bed253895a0b 281 SMART SM01133 22 254 1.8E-6 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_33860 44fc9d34193fe77c04b0bed253895a0b 281 Gene3D G3DSA:3.20.20.70 2 281 3.0E-60 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_33860 44fc9d34193fe77c04b0bed253895a0b 281 PIRSF PIRSF038992 2 281 3.1E-55 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_33860 44fc9d34193fe77c04b0bed253895a0b 281 Pfam PF01791 DeoC/LacD family aldolase 53 253 9.9E-20 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 Gene3D G3DSA:1.10.10.10 2 67 3.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 SMART SM00895 76 205 2.8E-16 T 12-10-2018 IPR011711 GntR, C-terminal AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 Gene3D G3DSA:1.20.120.530 74 215 1.4E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 SMART SM00345 8 66 7.0E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 SUPERFAMILY SSF48008 74 211 1.05E-19 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 SUPERFAMILY SSF46785 4 70 8.37E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 1.6E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_15180 9f8c371acd2e91c95eef2c2461016e13 221 Pfam PF07729 FCD domain 76 204 9.1E-25 T 12-10-2018 IPR011711 GntR, C-terminal AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 5.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 5.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 5.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 5.3E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 Gene3D G3DSA:3.40.50.720 1 255 3.2E-66 T 12-10-2018 AFR_02630 245babe02f606e995e6d7f22bc33b757 256 SUPERFAMILY SSF51735 7 252 1.32E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_02630 245babe02f606e995e6d7f22bc33b757 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02630 245babe02f606e995e6d7f22bc33b757 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 1.1E-45 T 12-10-2018 AFR_19225 24c06c8b19ed424ba4629af305d8f7c7 184 Pfam PF10646 Sporulation and spore germination 54 158 3.3E-8 T 12-10-2018 IPR019606 GerMN domain AFR_04735 56fb48ec3bdc71da63c3a652fd0641e0 309 SUPERFAMILY SSF51679 8 308 1.07E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_04735 56fb48ec3bdc71da63c3a652fd0641e0 309 Gene3D G3DSA:3.20.20.30 5 308 6.5E-71 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_04735 56fb48ec3bdc71da63c3a652fd0641e0 309 Pfam PF00296 Luciferase-like monooxygenase 8 248 1.5E-52 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_04735 56fb48ec3bdc71da63c3a652fd0641e0 309 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 5 223 3.3E-84 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c AFR_40195 f2cd7812c996d438d4850f9db9ed74b8 82 Pfam PF05768 Glutaredoxin-like domain (DUF836) 3 73 2.8E-14 T 12-10-2018 IPR008554 Glutaredoxin-like AFR_40195 f2cd7812c996d438d4850f9db9ed74b8 82 SUPERFAMILY SSF52833 2 75 1.37E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_40195 f2cd7812c996d438d4850f9db9ed74b8 82 Gene3D G3DSA:3.40.30.10 2 78 9.5E-20 T 12-10-2018 AFR_09390 7744220b83d9b69503781f774693ca22 311 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 139 246 3.9E-18 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09390 7744220b83d9b69503781f774693ca22 311 PRINTS PR01166 Cytochrome c oxidase subunit II signature 233 250 4.1E-12 T 12-10-2018 AFR_09390 7744220b83d9b69503781f774693ca22 311 PRINTS PR01166 Cytochrome c oxidase subunit II signature 135 154 4.1E-12 T 12-10-2018 AFR_09390 7744220b83d9b69503781f774693ca22 311 PRINTS PR01166 Cytochrome c oxidase subunit II signature 100 112 4.1E-12 T 12-10-2018 AFR_09390 7744220b83d9b69503781f774693ca22 311 PRINTS PR01166 Cytochrome c oxidase subunit II signature 194 214 4.1E-12 T 12-10-2018 AFR_09390 7744220b83d9b69503781f774693ca22 311 Gene3D G3DSA:2.60.40.2600 135 285 1.9E-42 T 12-10-2018 AFR_09390 7744220b83d9b69503781f774693ca22 311 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 55 119 1.3E-5 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09390 7744220b83d9b69503781f774693ca22 311 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 195 244 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09390 7744220b83d9b69503781f774693ca22 311 SUPERFAMILY SSF49503 136 265 2.32E-40 T 12-10-2018 IPR008972 Cupredoxin AFR_09390 7744220b83d9b69503781f774693ca22 311 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 56 260 2.7E-48 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09390 7744220b83d9b69503781f774693ca22 311 Gene3D G3DSA:1.10.287.90 54 129 1.5E-15 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09390 7744220b83d9b69503781f774693ca22 311 SUPERFAMILY SSF81464 44 131 2.62E-18 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 Pfam PF01047 MarR family 35 91 1.4E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 SUPERFAMILY SSF46785 31 134 2.92E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 SMART SM00347 26 126 1.5E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 Gene3D G3DSA:1.10.10.10 1 141 1.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 8.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 8.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31820 6cd732b13da90fdeb0cedeec0223572b 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 8.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_28870 c687a891b3b7efc27901afc2c2095cb3 300 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_28870 c687a891b3b7efc27901afc2c2095cb3 300 Pfam PF00005 ABC transporter 22 158 6.8E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_28870 c687a891b3b7efc27901afc2c2095cb3 300 SMART SM00382 30 216 2.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_28870 c687a891b3b7efc27901afc2c2095cb3 300 SUPERFAMILY SSF52540 3 219 3.61E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28870 c687a891b3b7efc27901afc2c2095cb3 300 Gene3D G3DSA:3.40.50.300 2 224 2.5E-59 T 12-10-2018 AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 SMART SM00347 36 136 1.3E-18 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 75 109 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 Gene3D G3DSA:1.10.10.10 3 149 1.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 Pfam PF01047 MarR family 43 99 6.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 9.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 9.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 9.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 9.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_15020 53f13bb0cc23d83a316ae3a8f1581f5c 157 SUPERFAMILY SSF46785 14 148 7.63E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10600 244e4988a9c85efd66df444b8d0ec458 194 Pfam PF04542 Sigma-70 region 2 42 108 1.0E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_10600 244e4988a9c85efd66df444b8d0ec458 194 SUPERFAMILY SSF88946 26 113 2.71E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_10600 244e4988a9c85efd66df444b8d0ec458 194 SUPERFAMILY SSF88659 139 190 8.22E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_10600 244e4988a9c85efd66df444b8d0ec458 194 Gene3D G3DSA:1.10.10.10 117 194 8.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10600 244e4988a9c85efd66df444b8d0ec458 194 Pfam PF08281 Sigma-70, region 4 134 184 1.6E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_10600 244e4988a9c85efd66df444b8d0ec458 194 Gene3D G3DSA:1.10.1740.10 21 107 2.7E-9 T 12-10-2018 AFR_10600 244e4988a9c85efd66df444b8d0ec458 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 189 2.9E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_21660 5c5faf52d9745526f5dc94dc2b2607cf 178 SUPERFAMILY SSF46689 4 77 6.16E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21660 5c5faf52d9745526f5dc94dc2b2607cf 178 Gene3D G3DSA:1.10.357.10 2 178 9.2E-49 T 12-10-2018 AFR_21660 5c5faf52d9745526f5dc94dc2b2607cf 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 6.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11580 a9662f619ec3f49a031ee6141b6dadbd 486 Pfam PF00535 Glycosyl transferase family 2 64 206 2.3E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_11580 a9662f619ec3f49a031ee6141b6dadbd 486 SUPERFAMILY SSF53448 62 364 5.34E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_11580 a9662f619ec3f49a031ee6141b6dadbd 486 Gene3D G3DSA:3.90.550.10 56 325 1.6E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_42515 bc871a3a0d33300aa5cbc38be0aca239 111 SMART SM00450 4 99 2.3E-19 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_42515 bc871a3a0d33300aa5cbc38be0aca239 111 Gene3D G3DSA:3.40.250.10 12 109 5.1E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_42515 bc871a3a0d33300aa5cbc38be0aca239 111 Pfam PF00581 Rhodanese-like domain 18 94 1.2E-16 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_42515 bc871a3a0d33300aa5cbc38be0aca239 111 SUPERFAMILY SSF52821 5 106 1.7E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_07015 a0f617d11bc7cbad1a04e2444a55eb30 338 Gene3D G3DSA:3.30.420.40 45 319 1.8E-70 T 12-10-2018 AFR_07015 a0f617d11bc7cbad1a04e2444a55eb30 338 SUPERFAMILY SSF53067 38 153 1.23E-17 T 12-10-2018 AFR_07015 a0f617d11bc7cbad1a04e2444a55eb30 338 Gene3D G3DSA:3.30.420.40 155 309 1.8E-70 T 12-10-2018 AFR_07015 a0f617d11bc7cbad1a04e2444a55eb30 338 Pfam PF00480 ROK family 39 319 7.2E-42 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_07015 a0f617d11bc7cbad1a04e2444a55eb30 338 SUPERFAMILY SSF53067 158 330 1.14E-43 T 12-10-2018 AFR_41730 ea5be7ab17e82a8cba9be42a86ee07a9 433 SMART SM00283 207 433 3.0E-6 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_41730 ea5be7ab17e82a8cba9be42a86ee07a9 433 Gene3D G3DSA:1.10.287.950 179 433 6.0E-36 T 12-10-2018 AFR_41730 ea5be7ab17e82a8cba9be42a86ee07a9 433 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 272 431 1.5E-27 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_41730 ea5be7ab17e82a8cba9be42a86ee07a9 433 SUPERFAMILY SSF58104 220 424 7.72E-40 T 12-10-2018 AFR_03515 187d0ee411e78369ff9b46e498afaf5b 375 Gene3D G3DSA:3.40.47.10 21 370 1.8E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_03515 187d0ee411e78369ff9b46e498afaf5b 375 SUPERFAMILY SSF53901 70 360 1.44E-20 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_03515 187d0ee411e78369ff9b46e498afaf5b 375 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 281 360 1.0E-10 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_15205 27756c7c52a2edb39df44724aa0c040b 689 Pfam PF05506 Domain of unknown function (DUF756) 599 672 6.4E-11 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFR_15205 27756c7c52a2edb39df44724aa0c040b 689 Pfam PF05506 Domain of unknown function (DUF756) 507 588 2.7E-20 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFR_15205 27756c7c52a2edb39df44724aa0c040b 689 Gene3D G3DSA:3.40.720.10 33 208 7.3E-30 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_15205 27756c7c52a2edb39df44724aa0c040b 689 Gene3D G3DSA:3.40.720.10 295 487 1.8E-45 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_15205 27756c7c52a2edb39df44724aa0c040b 689 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 686 8.4E-241 T 12-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFR_15205 27756c7c52a2edb39df44724aa0c040b 689 Pfam PF04185 Phosphoesterase family 44 432 4.9E-112 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 Gene3D G3DSA:3.40.50.720 3 221 1.3E-52 T 12-10-2018 AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 SUPERFAMILY SSF51735 2 220 4.78E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16780 4aa31a7a8c00aeda91705a84b29c1653 236 Pfam PF00106 short chain dehydrogenase 7 194 4.7E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 SUPERFAMILY SSF52172 19 66 7.47E-6 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 SMART SM00421 85 142 1.2E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 Pfam PF00196 Bacterial regulatory proteins, luxR family 87 142 2.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 118 130 6.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 102 118 6.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 88 102 6.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 Gene3D G3DSA:1.10.10.10 32 151 2.8E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 ProSitePatterns PS00622 LuxR-type HTH domain signature. 102 129 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28800 ba1aba9b12b97b0d4cd23ef93dfb0b2f 151 SUPERFAMILY SSF46894 81 148 2.01E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_14645 983a4f5db5a4b54a9c03bcd59f4ce30f 626 Gene3D G3DSA:2.60.40.10 42 134 1.3E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_14645 983a4f5db5a4b54a9c03bcd59f4ce30f 626 SUPERFAMILY SSF48208 138 621 1.17E-50 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_14645 983a4f5db5a4b54a9c03bcd59f4ce30f 626 Pfam PF02927 Cellulase N-terminal ig-like domain 43 123 1.4E-12 T 12-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 AFR_14645 983a4f5db5a4b54a9c03bcd59f4ce30f 626 Gene3D G3DSA:1.50.10.10 140 625 9.5E-52 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_14645 983a4f5db5a4b54a9c03bcd59f4ce30f 626 SUPERFAMILY SSF81296 34 133 4.83E-13 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_14645 983a4f5db5a4b54a9c03bcd59f4ce30f 626 Pfam PF00759 Glycosyl hydrolase family 9 143 614 4.9E-68 T 12-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 AFR_39840 8aa695b0165e6c1484c7d9f17517244e 529 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 108 207 2.2E-12 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFR_39840 8aa695b0165e6c1484c7d9f17517244e 529 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 333 524 1.0E-19 T 12-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 AFR_12610 2ed12bbc074d4e64974cb7809527fee3 306 SMART SM00829 6 304 1.1E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_12610 2ed12bbc074d4e64974cb7809527fee3 306 SUPERFAMILY SSF51735 117 265 4.67E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12610 2ed12bbc074d4e64974cb7809527fee3 306 Pfam PF13602 Zinc-binding dehydrogenase 192 304 7.2E-13 T 12-10-2018 AFR_12610 2ed12bbc074d4e64974cb7809527fee3 306 SUPERFAMILY SSF50129 1 151 1.02E-31 T 12-10-2018 IPR011032 GroES-like superfamily AFR_12610 2ed12bbc074d4e64974cb7809527fee3 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 23 87 1.0E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_12610 2ed12bbc074d4e64974cb7809527fee3 306 Gene3D G3DSA:3.40.50.720 128 255 8.3E-69 T 12-10-2018 AFR_12610 2ed12bbc074d4e64974cb7809527fee3 306 Gene3D G3DSA:3.90.180.10 4 303 8.3E-69 T 12-10-2018 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 Gene3D G3DSA:3.90.15.10 106 230 1.0E-69 T 12-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 Gene3D G3DSA:3.30.66.10 4 81 9.0E-32 T 12-10-2018 IPR035447 DNA topoisomerase I, N-terminal AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 SUPERFAMILY SSF56349 71 299 5.59E-60 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 161 177 9.5E-9 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 229 243 9.5E-9 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 115 134 9.5E-9 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 280 291 9.5E-9 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 SUPERFAMILY SSF55869 15 76 2.62E-20 T 12-10-2018 IPR035447 DNA topoisomerase I, N-terminal AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 76 284 1.6E-30 T 12-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 AFR_17495 6b36300abf98e2756e3c655bf6876e9b 314 Gene3D G3DSA:1.10.132.120 83 305 1.0E-69 T 12-10-2018 AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 SUPERFAMILY SSF51905 5 222 2.39E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 6 349 1.8E-109 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 Gene3D G3DSA:3.50.50.60 1 431 1.4E-141 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 2.0E-7 T 12-10-2018 AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.0E-7 T 12-10-2018 AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 220 2.0E-7 T 12-10-2018 AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 SUPERFAMILY SSF51905 181 348 3.7E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 202 227 6.2E-6 T 12-10-2018 AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 6.2E-6 T 12-10-2018 AFR_07915 2bfaa934c9f751a3f1b899b0e4943258 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 171 6.2E-6 T 12-10-2018 AFR_21065 8b964336e6dc82795fee2ba34f6a3b38 296 Pfam PF05949 Bacterial protein of unknown function (DUF881) 128 271 6.9E-35 T 12-10-2018 IPR010273 Protein of unknown function DUF881 AFR_21065 8b964336e6dc82795fee2ba34f6a3b38 296 Gene3D G3DSA:3.30.70.1880 126 280 9.1E-25 T 12-10-2018 AFR_20020 e9ebb3e57e592959877bfbc44826cf6f 174 Pfam PF08281 Sigma-70, region 4 107 158 8.8E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_20020 e9ebb3e57e592959877bfbc44826cf6f 174 Pfam PF04542 Sigma-70 region 2 13 72 1.6E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_20020 e9ebb3e57e592959877bfbc44826cf6f 174 Gene3D G3DSA:1.10.10.10 87 166 4.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20020 e9ebb3e57e592959877bfbc44826cf6f 174 SUPERFAMILY SSF88946 4 71 2.28E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_20020 e9ebb3e57e592959877bfbc44826cf6f 174 Gene3D G3DSA:1.10.1740.10 2 77 4.7E-11 T 12-10-2018 AFR_20020 e9ebb3e57e592959877bfbc44826cf6f 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 159 3.1E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_20020 e9ebb3e57e592959877bfbc44826cf6f 174 SUPERFAMILY SSF88659 89 164 2.43E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 SUPERFAMILY SSF116726 133 212 1.01E-13 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 Gene3D G3DSA:3.40.50.720 2 133 5.1E-30 T 12-10-2018 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 SUPERFAMILY SSF51735 1 145 1.01E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 Gene3D G3DSA:3.30.70.1450 136 219 2.0E-18 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 Pfam PF02254 TrkA-N domain 3 118 6.6E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 Pfam PF02080 TrkA-C domain 149 214 1.0E-13 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 9.0E-9 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 9.0E-9 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 9.0E-9 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFR_35275 4a731c9b7c267b3bbbce5077d0f41c1b 224 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 9.0E-9 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFR_33010 ef45cd8f31ffc391648aa4571514cb94 333 Pfam PF13439 Glycosyltransferase Family 4 27 128 9.1E-8 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_33010 ef45cd8f31ffc391648aa4571514cb94 333 Gene3D G3DSA:3.40.50.2000 13 331 8.0E-78 T 12-10-2018 AFR_33010 ef45cd8f31ffc391648aa4571514cb94 333 SUPERFAMILY SSF53756 9 332 3.41E-53 T 12-10-2018 AFR_33010 ef45cd8f31ffc391648aa4571514cb94 333 Pfam PF00534 Glycosyl transferases group 1 167 297 4.6E-19 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_33010 ef45cd8f31ffc391648aa4571514cb94 333 Gene3D G3DSA:3.40.50.2000 152 325 8.0E-78 T 12-10-2018 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 SUPERFAMILY SSF46785 3 107 3.4E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 Gene3D G3DSA:1.10.10.10 1 86 5.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 Gene3D G3DSA:3.40.190.10 93 280 2.7E-32 T 12-10-2018 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 SUPERFAMILY SSF53850 85 290 1.78E-32 T 12-10-2018 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 47 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 36 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 15 26 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 Gene3D G3DSA:3.40.190.10 164 263 2.7E-32 T 12-10-2018 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 59 2.3E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13370 f7515f5cc65aaa57c9dacb374dd1a3b7 293 Pfam PF03466 LysR substrate binding domain 84 287 2.1E-35 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_35760 245cbf4ca9381c35df41e2f8019f1472 261 Gene3D G3DSA:3.40.50.10790 3 88 3.1E-28 T 12-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AFR_35760 245cbf4ca9381c35df41e2f8019f1472 261 Gene3D G3DSA:3.40.50.10790 89 165 3.2E-23 T 12-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AFR_35760 245cbf4ca9381c35df41e2f8019f1472 261 PIRSF PIRSF006779 4 260 5.9E-68 T 12-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase AFR_35760 245cbf4ca9381c35df41e2f8019f1472 261 SUPERFAMILY SSF101852 169 258 5.62E-16 T 12-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal AFR_35760 245cbf4ca9381c35df41e2f8019f1472 261 Gene3D G3DSA:2.40.30.90 169 259 7.6E-16 T 12-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal AFR_35760 245cbf4ca9381c35df41e2f8019f1472 261 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 7 256 3.1E-74 T 12-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase AFR_35760 245cbf4ca9381c35df41e2f8019f1472 261 SUPERFAMILY SSF102522 5 164 4.45E-52 T 12-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AFR_07315 fbed024e1ae54543571fa59bc8c4da53 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 257 4.9E-37 T 12-10-2018 AFR_07315 fbed024e1ae54543571fa59bc8c4da53 266 Gene3D G3DSA:3.30.1240.10 84 186 1.6E-41 T 12-10-2018 AFR_07315 fbed024e1ae54543571fa59bc8c4da53 266 Gene3D G3DSA:3.40.50.1000 5 254 1.6E-41 T 12-10-2018 IPR023214 HAD superfamily AFR_07315 fbed024e1ae54543571fa59bc8c4da53 266 SUPERFAMILY SSF56784 5 260 1.33E-42 T 12-10-2018 IPR036412 HAD-like superfamily AFR_25575 9beddc064332ec05094fe4f11419b3a2 443 Pfam PF01757 Acyltransferase family 23 364 1.0E-20 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 Gene3D G3DSA:3.50.50.60 2 150 3.7E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 Gene3D G3DSA:3.50.50.60 423 505 2.2E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 Gene3D G3DSA:3.50.50.60 177 332 2.0E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 Pfam PF05199 GMC oxidoreductase 443 500 5.3E-18 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 SUPERFAMILY SSF51905 1 504 2.16E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 Pfam PF00732 GMC oxidoreductase 4 262 3.0E-8 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 446 461 3.1E-5 T 12-10-2018 AFR_34765 d61a0302650d8ae8bed8b9f8e9e87efd 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.1E-5 T 12-10-2018 AFR_20220 90dd2940cb6a150790db91c698fe033a 151 Gene3D G3DSA:1.10.10.10 9 148 8.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20220 90dd2940cb6a150790db91c698fe033a 151 SUPERFAMILY SSF46785 14 146 8.3E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19610 befdf65f8dbacfe66728145323dfa444 957 Pfam PF03413 Peptidase propeptide and YPEB domain 186 256 4.9E-5 T 12-10-2018 IPR025711 PepSY domain AFR_19610 befdf65f8dbacfe66728145323dfa444 957 Gene3D G3DSA:3.10.170.10 281 495 2.6E-44 T 12-10-2018 AFR_19610 befdf65f8dbacfe66728145323dfa444 957 Gene3D G3DSA:1.10.390.10 496 684 5.5E-40 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily AFR_19610 befdf65f8dbacfe66728145323dfa444 957 Pfam PF02128 Fungalysin metallopeptidase (M36) 309 671 6.7E-71 T 12-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 AFR_19610 befdf65f8dbacfe66728145323dfa444 957 SUPERFAMILY SSF55486 367 669 2.56E-34 T 12-10-2018 AFR_03600 98f8f9c168421a13f182bbfd6f8c2cdd 272 Gene3D G3DSA:3.30.1380.10 133 269 4.5E-15 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_03600 98f8f9c168421a13f182bbfd6f8c2cdd 272 SUPERFAMILY SSF55166 119 269 1.2E-20 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_03600 98f8f9c168421a13f182bbfd6f8c2cdd 272 SUPERFAMILY SSF54106 37 80 4.05E-7 T 12-10-2018 AFR_03600 98f8f9c168421a13f182bbfd6f8c2cdd 272 SMART SM00257 37 81 5.0E-6 T 12-10-2018 IPR018392 LysM domain AFR_03600 98f8f9c168421a13f182bbfd6f8c2cdd 272 Pfam PF01476 LysM domain 38 78 5.3E-7 T 12-10-2018 IPR018392 LysM domain AFR_03600 98f8f9c168421a13f182bbfd6f8c2cdd 272 Gene3D G3DSA:3.10.350.10 23 85 8.1E-10 T 12-10-2018 IPR036779 LysM domain superfamily AFR_03600 98f8f9c168421a13f182bbfd6f8c2cdd 272 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 191 269 7.0E-20 T 12-10-2018 IPR039561 Peptidase M15C GO:0008233 AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 Pfam PF00271 Helicase conserved C-terminal domain 812 921 4.8E-16 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 SUPERFAMILY SSF52540 496 724 9.23E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 SUPERFAMILY SSF52540 727 978 5.47E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 Gene3D G3DSA:3.40.50.10810 480 727 1.2E-67 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 SMART SM00490 837 921 2.1E-20 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 SMART SM00487 505 704 8.6E-33 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 Pfam PF00176 SNF2 family N-terminal domain 528 793 8.6E-58 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 Pfam PF12419 SNF2 Helicase protein 329 465 1.0E-38 T 12-10-2018 IPR022138 Helicase SWF/SNF-related AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 Gene3D G3DSA:1.20.120.850 748 971 8.7E-92 T 12-10-2018 AFR_01615 004d9d70ae80466e1a0cd7497975c5e1 983 Gene3D G3DSA:3.40.50.300 733 935 8.7E-92 T 12-10-2018 AFR_10220 6cf2696902aa9f436035460770aae90e 227 Pfam PF00072 Response regulator receiver domain 5 112 3.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_10220 6cf2696902aa9f436035460770aae90e 227 SMART SM00448 2 112 3.7E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_10220 6cf2696902aa9f436035460770aae90e 227 SMART SM00862 147 223 6.1E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_10220 6cf2696902aa9f436035460770aae90e 227 SUPERFAMILY SSF52172 3 168 1.61E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_10220 6cf2696902aa9f436035460770aae90e 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 7.2E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_10220 6cf2696902aa9f436035460770aae90e 227 Gene3D G3DSA:3.40.50.2300 1 118 9.2E-32 T 12-10-2018 AFR_10220 6cf2696902aa9f436035460770aae90e 227 Gene3D G3DSA:1.10.10.10 119 226 1.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39290 cead1d8d4c946baad1551b76087d8219 599 Gene3D G3DSA:3.90.228.20 235 593 2.1E-276 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 12 231 1.9E-101 T 12-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 259 267 - T 12-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 235 596 3.2E-173 T 12-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 SUPERFAMILY SSF53795 235 597 6.64E-160 T 12-10-2018 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 Gene3D G3DSA:2.170.8.10 47 388 2.1E-276 T 12-10-2018 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 SUPERFAMILY SSF68923 4 234 5.07E-98 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 PIRSF PIRSF001348 2 599 6.6E-283 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 Gene3D G3DSA:3.40.449.10 11 234 2.1E-276 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AFR_39290 cead1d8d4c946baad1551b76087d8219 599 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 1 597 50.276 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 AFR_34385 6ca81aff3b3ff9941219bcd9c502c800 302 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_34385 6ca81aff3b3ff9941219bcd9c502c800 302 Pfam PF00294 pfkB family carbohydrate kinase 180 290 1.4E-14 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_34385 6ca81aff3b3ff9941219bcd9c502c800 302 Pfam PF00294 pfkB family carbohydrate kinase 42 110 4.2E-5 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_34385 6ca81aff3b3ff9941219bcd9c502c800 302 Gene3D G3DSA:3.40.1190.20 1 302 2.0E-37 T 12-10-2018 IPR029056 Ribokinase-like AFR_34385 6ca81aff3b3ff9941219bcd9c502c800 302 SUPERFAMILY SSF53613 1 291 7.95E-35 T 12-10-2018 IPR029056 Ribokinase-like AFR_32940 d4c11f3496b3ac833b423ae83946a7fd 202 SUPERFAMILY SSF88946 29 104 9.42E-7 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_32940 d4c11f3496b3ac833b423ae83946a7fd 202 Gene3D G3DSA:1.10.1740.10 22 107 6.6E-10 T 12-10-2018 AFR_32940 d4c11f3496b3ac833b423ae83946a7fd 202 SUPERFAMILY SSF88659 129 186 2.43E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_32940 d4c11f3496b3ac833b423ae83946a7fd 202 Gene3D G3DSA:1.10.10.10 127 193 4.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32940 d4c11f3496b3ac833b423ae83946a7fd 202 Pfam PF04545 Sigma-70, region 4 135 183 4.4E-7 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 Gene3D G3DSA:2.40.50.140 1 65 4.4E-31 T 12-10-2018 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 PRINTS PR00050 Cold shock protein signature 4 19 6.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 PRINTS PR00050 Cold shock protein signature 25 34 6.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 PRINTS PR00050 Cold shock protein signature 40 58 6.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 12-10-2018 IPR019844 Cold-shock conserved site AFR_38465 1cd134efd414391b782ddd2da89cb959 67 SMART SM00357 3 67 3.4E-33 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 Pfam PF00313 'Cold-shock' DNA-binding domain 2 65 1.3E-32 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 PIRSF PIRSF002599 1 67 9.3E-26 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFR_38465 1cd134efd414391b782ddd2da89cb959 67 SUPERFAMILY SSF50249 1 66 8.36E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_31695 622707c30cd6f407716e7b7f83d40d83 207 SUPERFAMILY SSF53335 31 204 2.19E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_31695 622707c30cd6f407716e7b7f83d40d83 207 Gene3D G3DSA:3.40.50.150 2 205 1.7E-62 T 12-10-2018 AFR_31695 622707c30cd6f407716e7b7f83d40d83 207 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 28 204 7.7E-43 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFR_31695 622707c30cd6f407716e7b7f83d40d83 207 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 205 27.633 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFR_31695 622707c30cd6f407716e7b7f83d40d83 207 Pfam PF02390 Putative methyltransferase 38 200 4.8E-48 T 12-10-2018 AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PIRSF PIRSF000126 1 265 4.0E-61 T 12-10-2018 AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 9.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 9.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 Pfam PF00106 short chain dehydrogenase 14 199 4.0E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 SUPERFAMILY SSF51735 14 258 3.57E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38290 8263e4af96accb66c35c9a59ffdc90a1 267 Gene3D G3DSA:3.40.50.720 12 259 2.0E-53 T 12-10-2018 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 Pfam PF02056 Family 4 glycosyl hydrolase 2 178 1.5E-41 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 SUPERFAMILY SSF51735 2 155 1.05E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 Gene3D G3DSA:3.40.50.720 3 161 2.2E-119 T 12-10-2018 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 189 393 8.8E-35 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 SUPERFAMILY SSF56327 164 414 1.21E-56 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 PRINTS PR00732 Glycosyl hydrolase family 4 signature 184 196 3.0E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 PRINTS PR00732 Glycosyl hydrolase family 4 signature 69 85 3.0E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 3.0E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 PRINTS PR00732 Glycosyl hydrolase family 4 signature 90 103 3.0E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 PRINTS PR00732 Glycosyl hydrolase family 4 signature 104 124 3.0E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 PRINTS PR00732 Glycosyl hydrolase family 4 signature 158 169 3.0E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_41250 48bd4f7c307324300ce9e10e14351bce 418 Gene3D G3DSA:3.90.110.10 82 411 2.2E-119 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFR_13920 8bbbd4d1269e2c223ec423e4bd6e3bf5 754 Pfam PF03176 MMPL family 90 410 3.4E-35 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_13920 8bbbd4d1269e2c223ec423e4bd6e3bf5 754 Pfam PF03176 MMPL family 504 742 5.7E-32 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_13920 8bbbd4d1269e2c223ec423e4bd6e3bf5 754 SUPERFAMILY SSF82866 523 731 1.31E-23 T 12-10-2018 AFR_13920 8bbbd4d1269e2c223ec423e4bd6e3bf5 754 SUPERFAMILY SSF82866 162 380 2.22E-22 T 12-10-2018 AFR_13920 8bbbd4d1269e2c223ec423e4bd6e3bf5 754 Gene3D G3DSA:1.20.1640.10 193 383 5.6E-8 T 12-10-2018 AFR_41655 c44b30cb0ff0b28f7bd10ec9dc70a864 304 SUPERFAMILY SSF52540 1 219 1.83E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41655 c44b30cb0ff0b28f7bd10ec9dc70a864 304 Pfam PF02374 Anion-transporting ATPase 1 161 9.7E-18 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 AFR_41655 c44b30cb0ff0b28f7bd10ec9dc70a864 304 Gene3D G3DSA:3.40.50.300 1 304 2.1E-45 T 12-10-2018 AFR_33400 49f9d906b15cc469aa6e5c07ef16ed17 107 SMART SM00418 6 84 6.1E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33400 49f9d906b15cc469aa6e5c07ef16ed17 107 Gene3D G3DSA:1.10.10.10 1 105 7.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33400 49f9d906b15cc469aa6e5c07ef16ed17 107 Pfam PF12840 Helix-turn-helix domain 7 62 1.9E-15 T 12-10-2018 AFR_33400 49f9d906b15cc469aa6e5c07ef16ed17 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 7.5E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33400 49f9d906b15cc469aa6e5c07ef16ed17 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 7.5E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33400 49f9d906b15cc469aa6e5c07ef16ed17 107 SUPERFAMILY SSF46785 1 103 3.2E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17455 1e38f6d97df09ecd12c6c6480e1027e4 218 Gene3D G3DSA:3.40.50.880 2 213 1.9E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_17455 1e38f6d97df09ecd12c6c6480e1027e4 218 Pfam PF01965 DJ-1/PfpI family 101 184 4.1E-9 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_17455 1e38f6d97df09ecd12c6c6480e1027e4 218 SUPERFAMILY SSF52317 4 203 4.23E-26 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_40725 f7e7fb6a28c47a4a012deae020762553 111 Pfam PF07210 Protein of unknown function (DUF1416) 13 109 5.5E-41 T 12-10-2018 IPR010814 Protein of unknown function DUF1416 AFR_40725 f7e7fb6a28c47a4a012deae020762553 111 SUPERFAMILY SSF49478 34 91 1.92E-8 T 12-10-2018 AFR_40725 f7e7fb6a28c47a4a012deae020762553 111 Gene3D G3DSA:2.60.40.1120 33 107 7.4E-6 T 12-10-2018 AFR_39155 b6a10f5a705deb221f1994ca651733e4 190 Gene3D G3DSA:1.10.10.10 81 168 4.6E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39155 b6a10f5a705deb221f1994ca651733e4 190 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 88 166 6.4E-27 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFR_39155 b6a10f5a705deb221f1994ca651733e4 190 SUPERFAMILY SSF46767 87 167 2.88E-25 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AFR_39155 b6a10f5a705deb221f1994ca651733e4 190 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 137 143 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFR_39155 b6a10f5a705deb221f1994ca651733e4 190 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 89 167 1.2E-24 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 SUPERFAMILY SSF56655 6 257 6.41E-48 T 12-10-2018 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 Gene3D G3DSA:3.30.540.10 3 135 1.5E-29 T 12-10-2018 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 6.5E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 6.5E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 6.5E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 6.5E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 6.5E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 Pfam PF00459 Inositol monophosphatase family 7 256 1.6E-37 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_34655 2eea87ddde182fe7b107ed5366dde919 267 Gene3D G3DSA:3.40.190.80 168 266 1.0E-14 T 12-10-2018 AFR_01260 23b85d2f3b90e6c8e8f5d9987b61ca7d 390 SUPERFAMILY SSF55103 207 369 1.7E-8 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFR_01260 23b85d2f3b90e6c8e8f5d9987b61ca7d 390 Gene3D G3DSA:3.30.465.40 9 215 9.2E-32 T 12-10-2018 AFR_01260 23b85d2f3b90e6c8e8f5d9987b61ca7d 390 SUPERFAMILY SSF56176 10 202 9.81E-24 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_01260 23b85d2f3b90e6c8e8f5d9987b61ca7d 390 Pfam PF01565 FAD binding domain 38 170 2.8E-21 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_14495 8165f0ea2d928d97fbbf25dfe187aba4 235 SMART SM00065 25 172 1.3E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_14495 8165f0ea2d928d97fbbf25dfe187aba4 235 Gene3D G3DSA:3.30.450.40 7 172 1.6E-23 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_14495 8165f0ea2d928d97fbbf25dfe187aba4 235 Pfam PF03861 ANTAR domain 177 229 1.8E-11 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_14495 8165f0ea2d928d97fbbf25dfe187aba4 235 PIRSF PIRSF036625 2 234 1.6E-40 T 12-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative AFR_14495 8165f0ea2d928d97fbbf25dfe187aba4 235 SUPERFAMILY SSF55781 25 170 1.74E-21 T 12-10-2018 AFR_14495 8165f0ea2d928d97fbbf25dfe187aba4 235 Pfam PF13185 GAF domain 24 162 4.8E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_14495 8165f0ea2d928d97fbbf25dfe187aba4 235 SMART SM01012 174 229 3.3E-7 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_18690 197aebc9a1e529920d504cd7f7afff70 107 Pfam PF00355 Rieske [2Fe-2S] domain 4 80 8.1E-15 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFR_18690 197aebc9a1e529920d504cd7f7afff70 107 Gene3D G3DSA:2.102.10.10 1 102 8.6E-24 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_18690 197aebc9a1e529920d504cd7f7afff70 107 SUPERFAMILY SSF50022 2 91 1.7E-24 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_22195 bb0735b91e0581449562707748947df7 320 Gene3D G3DSA:3.40.109.10 101 319 4.0E-47 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_22195 bb0735b91e0581449562707748947df7 320 SUPERFAMILY SSF55469 112 319 3.43E-7 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_22195 bb0735b91e0581449562707748947df7 320 SUPERFAMILY SSF55469 4 79 6.71E-8 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_22195 bb0735b91e0581449562707748947df7 320 Gene3D G3DSA:3.40.109.10 2 97 2.3E-32 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 Pfam PF02779 Transketolase, pyrimidine binding domain 368 548 1.9E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 352 1.1E-126 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 687 1.1E-234 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 Gene3D G3DSA:3.40.50.970 1 348 8.3E-112 T 12-10-2018 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 SUPERFAMILY SSF52922 557 693 1.36E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 SUPERFAMILY SSF52518 3 336 6.16E-101 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 Pfam PF02780 Transketolase, C-terminal domain 575 681 4.4E-10 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 ProSitePatterns PS00801 Transketolase signature 1. 15 35 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 Gene3D G3DSA:3.40.50.970 349 559 1.3E-79 T 12-10-2018 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 SMART SM00861 369 549 2.7E-67 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 Gene3D G3DSA:3.40.50.920 564 690 1.8E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_10640 f47fe00d584e9390ed7ed7314e5b7a3c 702 SUPERFAMILY SSF52518 351 549 2.56E-66 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 Pfam PF07730 Histidine kinase 178 245 4.5E-18 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 SMART SM00387 282 373 1.7E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 Pfam PF13185 GAF domain 24 161 4.3E-21 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 332 5.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 352 5.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 371 5.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 Gene3D G3DSA:3.30.450.40 24 171 3.4E-47 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 373 8.3E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 SMART SM00065 24 171 1.7E-23 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 Gene3D G3DSA:3.30.565.10 255 372 9.0E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 SUPERFAMILY SSF55874 275 372 7.99E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_16785 72673a6caee89d2ba48dd6ea06a65e17 373 SUPERFAMILY SSF55781 8 175 1.29E-32 T 12-10-2018 AFR_08680 3b9792fa476bfb5d89962d5e369ec5a0 271 Pfam PF13602 Zinc-binding dehydrogenase 158 268 1.6E-11 T 12-10-2018 AFR_08680 3b9792fa476bfb5d89962d5e369ec5a0 271 SUPERFAMILY SSF51735 90 240 2.78E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_08680 3b9792fa476bfb5d89962d5e369ec5a0 271 SMART SM00829 3 268 6.0E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_08680 3b9792fa476bfb5d89962d5e369ec5a0 271 Gene3D G3DSA:3.90.180.10 1 267 1.0E-61 T 12-10-2018 AFR_08680 3b9792fa476bfb5d89962d5e369ec5a0 271 SUPERFAMILY SSF50129 3 123 1.13E-28 T 12-10-2018 IPR011032 GroES-like superfamily AFR_08680 3b9792fa476bfb5d89962d5e369ec5a0 271 Gene3D G3DSA:3.40.50.720 101 219 1.0E-61 T 12-10-2018 AFR_08680 3b9792fa476bfb5d89962d5e369ec5a0 271 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 118 139 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFR_10660 136fee0bd64f1f8055cfa38b4d951fa1 254 Pfam PF01022 Bacterial regulatory protein, arsR family 36 74 1.1E-4 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_10660 136fee0bd64f1f8055cfa38b4d951fa1 254 SUPERFAMILY SSF46785 27 215 2.21E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10660 136fee0bd64f1f8055cfa38b4d951fa1 254 Gene3D G3DSA:1.10.10.10 22 140 7.0E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33525 6cd05a903dfafb889fb6b28dec9ea8d2 278 SUPERFAMILY SSF52540 3 219 7.61E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33525 6cd05a903dfafb889fb6b28dec9ea8d2 278 SMART SM00382 28 213 2.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33525 6cd05a903dfafb889fb6b28dec9ea8d2 278 Gene3D G3DSA:3.40.50.300 1 226 1.1E-59 T 12-10-2018 AFR_33525 6cd05a903dfafb889fb6b28dec9ea8d2 278 Pfam PF00005 ABC transporter 20 157 2.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_33525 6cd05a903dfafb889fb6b28dec9ea8d2 278 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10125 7916cb458ac544bfdaa3f4822e244d39 207 Pfam PF00117 Glutamine amidotransferase class-I 6 195 6.9E-20 T 12-10-2018 IPR017926 Glutamine amidotransferase AFR_10125 7916cb458ac544bfdaa3f4822e244d39 207 Gene3D G3DSA:3.40.50.880 1 206 4.1E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_10125 7916cb458ac544bfdaa3f4822e244d39 207 PIRSF PIRSF000495 2 207 5.0E-63 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFR_10125 7916cb458ac544bfdaa3f4822e244d39 207 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 205 32.226 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFR_10125 7916cb458ac544bfdaa3f4822e244d39 207 SMART SM01211 1 206 0.0023 T 12-10-2018 AFR_10125 7916cb458ac544bfdaa3f4822e244d39 207 SUPERFAMILY SSF52317 3 204 4.17E-53 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_10125 7916cb458ac544bfdaa3f4822e244d39 207 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 204 2.9E-62 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFR_24170 cb8c60c54ec896be7b8ed6db7894640e 268 PIRSF PIRSF017393 2 268 3.4E-78 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_24170 cb8c60c54ec896be7b8ed6db7894640e 268 Pfam PF04672 S-adenosyl methyltransferase 7 267 6.9E-74 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_24170 cb8c60c54ec896be7b8ed6db7894640e 268 Gene3D G3DSA:3.40.50.150 2 267 2.1E-91 T 12-10-2018 AFR_24170 cb8c60c54ec896be7b8ed6db7894640e 268 SUPERFAMILY SSF53335 17 247 3.52E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_31185 e78f22282aef8faf8c2f0d5ebc78ba67 734 Gene3D G3DSA:2.60.40.10 509 590 5.0E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31185 e78f22282aef8faf8c2f0d5ebc78ba67 734 Gene3D G3DSA:2.80.10.50 597 732 1.1E-19 T 12-10-2018 AFR_31185 e78f22282aef8faf8c2f0d5ebc78ba67 734 SUPERFAMILY SSF49265 508 576 9.4E-7 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_31185 e78f22282aef8faf8c2f0d5ebc78ba67 734 SUPERFAMILY SSF50370 594 730 1.17E-19 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_31185 e78f22282aef8faf8c2f0d5ebc78ba67 734 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 597 672 2.8E-9 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_31185 e78f22282aef8faf8c2f0d5ebc78ba67 734 SMART SM00060 510 580 6.5E-4 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_36755 f4f960d9fde2febc0a6d2403ffbd7c86 145 SUPERFAMILY SSF75620 13 126 2.82E-11 T 12-10-2018 AFR_36755 f4f960d9fde2febc0a6d2403ffbd7c86 145 Gene3D G3DSA:3.30.160.20 8 143 6.9E-32 T 12-10-2018 AFR_36755 f4f960d9fde2febc0a6d2403ffbd7c86 145 Pfam PF00472 RF-1 domain 15 140 1.2E-20 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFR_40520 cd5b69571ac000da2bea120683dc0aa2 254 Pfam PF01311 Bacterial export proteins, family 1 11 242 3.4E-61 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFR_40520 cd5b69571ac000da2bea120683dc0aa2 254 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 177 199 2.6E-26 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFR_40520 cd5b69571ac000da2bea120683dc0aa2 254 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 19 40 2.6E-26 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFR_40520 cd5b69571ac000da2bea120683dc0aa2 254 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 199 218 2.6E-26 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFR_40520 cd5b69571ac000da2bea120683dc0aa2 254 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 77 96 2.6E-26 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFR_40520 cd5b69571ac000da2bea120683dc0aa2 254 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 11 246 4.0E-51 T 12-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 SUPERFAMILY SSF51905 1 355 1.24E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37560 29bf5402b16389c02b3316191b31fedf 514 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 6 323 1.8E-50 T 12-10-2018 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 304 326 8.5E-12 T 12-10-2018 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 8.5E-12 T 12-10-2018 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.5E-12 T 12-10-2018 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 8.5E-12 T 12-10-2018 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 Gene3D G3DSA:3.50.50.60 6 361 1.5E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37560 29bf5402b16389c02b3316191b31fedf 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 314 332 5.3E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 5.3E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 173 197 5.3E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_37560 29bf5402b16389c02b3316191b31fedf 514 Gene3D G3DSA:3.50.50.60 152 281 1.5E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_35060 f777b4e17fca04e2a20d4aa71e9959eb 523 SUPERFAMILY SSF53474 109 495 6.28E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_35060 f777b4e17fca04e2a20d4aa71e9959eb 523 Pfam PF00561 alpha/beta hydrolase fold 112 494 1.2E-36 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_22440 a35a0adff585f0d50e226d6083a7f938 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 281 2.4E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_22440 a35a0adff585f0d50e226d6083a7f938 288 Gene3D G3DSA:1.10.3720.10 36 287 3.3E-69 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22440 a35a0adff585f0d50e226d6083a7f938 288 SUPERFAMILY SSF161098 40 274 9.42E-56 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22440 a35a0adff585f0d50e226d6083a7f938 288 SUPERFAMILY SSF160964 2 32 3.27E-5 T 12-10-2018 AFR_19985 4c36b6eeeccd7f55f7b367939144b5a5 196 Gene3D G3DSA:3.30.70.3040 90 190 5.2E-18 T 12-10-2018 AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 SUPERFAMILY SSF141868 553 797 8.5E-77 T 12-10-2018 IPR035919 EAL domain superfamily AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 SUPERFAMILY SSF55781 244 375 7.2E-7 T 12-10-2018 AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 SUPERFAMILY SSF55073 383 534 2.98E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 377 535 5.7E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 SMART SM00267 367 536 2.6E-47 T 12-10-2018 IPR000160 GGDEF domain AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 Pfam PF00990 Diguanylate cyclase, GGDEF domain 378 532 2.3E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 Gene3D G3DSA:3.30.70.270 373 541 2.1E-49 T 12-10-2018 AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 Gene3D G3DSA:3.20.20.450 547 802 4.9E-85 T 12-10-2018 IPR035919 EAL domain superfamily AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 Pfam PF00563 EAL domain 553 786 1.6E-68 T 12-10-2018 IPR001633 EAL domain AFR_42740 880a544bb205c1aca7ea49cba51592a2 838 SMART SM00052 546 791 1.4E-86 T 12-10-2018 IPR001633 EAL domain AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 2.4E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 61 2.4E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 2.4E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 28 43 2.4E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 SUPERFAMILY SSF46785 14 105 1.04E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 52 70 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 Pfam PF01022 Bacterial regulatory protein, arsR family 33 82 1.0E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 Gene3D G3DSA:1.10.10.10 9 109 2.9E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10435 0cc01e300ba1d4946d36dbae59835b67 113 SMART SM00418 26 106 3.8E-31 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 SUPERFAMILY SSF55252 85 141 1.44E-17 T 12-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 Pfam PF01316 Arginine repressor, DNA binding domain 7 65 1.4E-18 T 12-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 Gene3D G3DSA:3.30.1360.40 77 154 2.6E-26 T 12-10-2018 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 Hamap MF_00173 Arginine repressor [argR]. 1 159 51.589 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 93 143 1.0E-13 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 SUPERFAMILY SSF46785 6 66 5.29E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 Pfam PF02863 Arginine repressor, C-terminal domain 85 143 4.4E-23 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 PRINTS PR01467 Bacterial arginine repressor signature 41 56 7.3E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 PRINTS PR01467 Bacterial arginine repressor signature 25 38 7.3E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 PRINTS PR01467 Bacterial arginine repressor signature 93 106 7.3E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 PRINTS PR01467 Bacterial arginine repressor signature 123 138 7.3E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 Gene3D G3DSA:1.10.10.10 2 71 4.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30220 eaf9258816c3c1fcdbf25d5065707680 165 TIGRFAM TIGR01529 argR_whole: arginine repressor 9 144 3.2E-39 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFR_37715 22faeeeeb76923258a12a46d0244b104 499 Gene3D G3DSA:2.60.40.650 389 499 1.4E-24 T 12-10-2018 AFR_37715 22faeeeeb76923258a12a46d0244b104 499 Pfam PF00174 Oxidoreductase molybdopterin binding domain 225 372 4.6E-35 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFR_37715 22faeeeeb76923258a12a46d0244b104 499 Gene3D G3DSA:3.90.420.10 169 388 6.5E-45 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_37715 22faeeeeb76923258a12a46d0244b104 499 SUPERFAMILY SSF81296 389 497 3.85E-22 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_37715 22faeeeeb76923258a12a46d0244b104 499 SUPERFAMILY SSF56524 208 396 7.85E-51 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 Gene3D G3DSA:3.40.50.720 2 245 1.2E-69 T 12-10-2018 AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 244 6.8E-56 T 12-10-2018 AFR_10875 67f69f14ff749257d3dc362bf0f00acb 246 SUPERFAMILY SSF51735 5 245 1.76E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37730 6501da58441b2aaea31e40b255ad875e 251 Pfam PF10099 Anti-sigma-K factor rskA 57 247 6.4E-25 T 12-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 AFR_37730 6501da58441b2aaea31e40b255ad875e 251 Gene3D G3DSA:1.10.10.1320 1 70 4.4E-22 T 12-10-2018 AFR_37730 6501da58441b2aaea31e40b255ad875e 251 Pfam PF13490 Putative zinc-finger 4 36 8.8E-7 T 12-10-2018 IPR027383 Putative zinc-finger AFR_05090 757e2569ff43ade4249e23fb10f08287 392 Gene3D G3DSA:3.30.1490.20 21 96 4.7E-77 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 388 7.8E-122 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 SUPERFAMILY SSF56059 3 227 7.42E-65 T 12-10-2018 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 389 37.1 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 Gene3D G3DSA:3.40.50.261 232 390 1.6E-44 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 SUPERFAMILY SSF52210 231 387 9.55E-40 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 PIRSF PIRSF001554 1 391 3.0E-131 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 Gene3D G3DSA:3.30.470.20 2 226 4.7E-77 T 12-10-2018 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 Pfam PF00549 CoA-ligase 256 366 4.1E-12 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFR_05090 757e2569ff43ade4249e23fb10f08287 392 Pfam PF08442 ATP-grasp domain 2 194 6.6E-68 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 Pfam PF00561 alpha/beta hydrolase fold 56 191 6.8E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 1.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 96 1.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 140 153 1.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 SUPERFAMILY SSF53474 29 314 4.24E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11945 d078592e15a98c01459d542fd45acd9f 314 PRINTS PR00412 Epoxide hydrolase signature 126 139 2.8E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 PRINTS PR00412 Epoxide hydrolase signature 140 153 2.8E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 PRINTS PR00412 Epoxide hydrolase signature 62 80 2.8E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 PRINTS PR00412 Epoxide hydrolase signature 290 312 2.8E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11945 d078592e15a98c01459d542fd45acd9f 314 Gene3D G3DSA:3.40.50.1820 34 314 3.5E-83 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16045 cb08ff47de33fd28a91a36609fc2d646 323 SMART SM00829 10 321 1.3E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_16045 cb08ff47de33fd28a91a36609fc2d646 323 SUPERFAMILY SSF50129 1 151 1.09E-24 T 12-10-2018 IPR011032 GroES-like superfamily AFR_16045 cb08ff47de33fd28a91a36609fc2d646 323 Gene3D G3DSA:3.40.50.720 126 267 2.7E-78 T 12-10-2018 AFR_16045 cb08ff47de33fd28a91a36609fc2d646 323 Pfam PF00107 Zinc-binding dehydrogenase 153 264 4.9E-20 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_16045 cb08ff47de33fd28a91a36609fc2d646 323 SUPERFAMILY SSF51735 114 264 9.69E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16045 cb08ff47de33fd28a91a36609fc2d646 323 Gene3D G3DSA:3.90.180.10 10 317 2.7E-78 T 12-10-2018 AFR_01325 78295882ba52e204a1f473b51964c4ed 218 PIRSF PIRSF000709 3 83 0.0072 T 12-10-2018 AFR_01325 78295882ba52e204a1f473b51964c4ed 218 Gene3D G3DSA:3.40.50.1240 2 201 1.7E-28 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_01325 78295882ba52e204a1f473b51964c4ed 218 SMART SM00855 8 160 6.9E-17 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_01325 78295882ba52e204a1f473b51964c4ed 218 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 10 194 1.4E-34 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_01325 78295882ba52e204a1f473b51964c4ed 218 SUPERFAMILY SSF53254 7 197 1.26E-35 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_20070 1bee0dc67ad00d0628547682d25c7c74 142 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 23 138 2.9E-37 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III AFR_15895 c552bb2b8de76963868309cd5b5c19e4 357 Gene3D G3DSA:3.30.360.10 136 301 4.4E-81 T 12-10-2018 AFR_15895 c552bb2b8de76963868309cd5b5c19e4 357 Gene3D G3DSA:3.40.50.720 14 334 4.4E-81 T 12-10-2018 AFR_15895 c552bb2b8de76963868309cd5b5c19e4 357 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 13 130 3.4E-25 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_15895 c552bb2b8de76963868309cd5b5c19e4 357 SUPERFAMILY SSF55347 137 274 1.11E-15 T 12-10-2018 AFR_15895 c552bb2b8de76963868309cd5b5c19e4 357 SUPERFAMILY SSF51735 5 159 4.23E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 Hamap MF_00300 Chorismate synthase [aroC]. 2 374 34.62 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 Pfam PF01264 Chorismate synthase 2 365 2.9E-116 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 Gene3D G3DSA:3.60.150.10 1 392 1.0E-156 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 TIGRFAM TIGR00033 aroC: chorismate synthase 2 371 6.4E-127 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 PIRSF PIRSF001456 1 384 8.8E-125 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 ProSitePatterns PS00789 Chorismate synthase signature 3. 341 357 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_30685 e0348547a7783efc69f2b5228c3ffa1f 392 SUPERFAMILY SSF103263 2 388 5.1E-135 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFR_22300 4118cb6b8f9291b942ffb0db285140a8 382 Pfam PF00296 Luciferase-like monooxygenase 5 329 9.2E-79 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_22300 4118cb6b8f9291b942ffb0db285140a8 382 SUPERFAMILY SSF51679 5 359 1.7E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22300 4118cb6b8f9291b942ffb0db285140a8 382 Gene3D G3DSA:3.20.20.30 2 358 2.6E-123 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_15965 713b109439d0de2d3e8fd6f02debe3dc 276 Pfam PF01061 ABC-2 type transporter 46 228 1.4E-13 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_05985 f924b45075b69a2dce9d683222bc021c 410 Pfam PF00482 Type II secretion system (T2SS), protein F 73 196 1.4E-28 T 12-10-2018 IPR018076 Type II secretion system F domain AFR_05985 f924b45075b69a2dce9d683222bc021c 410 Pfam PF00482 Type II secretion system (T2SS), protein F 277 399 6.4E-32 T 12-10-2018 IPR018076 Type II secretion system F domain AFR_05985 f924b45075b69a2dce9d683222bc021c 410 PRINTS PR00812 Bacterial general secretion pathway protein F signature 69 81 2.0E-12 T 12-10-2018 IPR003004 GspF/PilC family AFR_05985 f924b45075b69a2dce9d683222bc021c 410 PRINTS PR00812 Bacterial general secretion pathway protein F signature 388 407 2.0E-12 T 12-10-2018 IPR003004 GspF/PilC family AFR_05985 f924b45075b69a2dce9d683222bc021c 410 PRINTS PR00812 Bacterial general secretion pathway protein F signature 168 196 2.0E-12 T 12-10-2018 IPR003004 GspF/PilC family AFR_05985 f924b45075b69a2dce9d683222bc021c 410 PRINTS PR00812 Bacterial general secretion pathway protein F signature 372 386 2.0E-12 T 12-10-2018 IPR003004 GspF/PilC family AFR_05985 f924b45075b69a2dce9d683222bc021c 410 Gene3D G3DSA:1.20.81.30 260 371 3.2E-32 T 12-10-2018 AFR_05985 f924b45075b69a2dce9d683222bc021c 410 Gene3D G3DSA:1.20.81.30 56 172 2.0E-30 T 12-10-2018 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 135 150 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 Gene3D G3DSA:3.90.190.20 294 435 2.5E-36 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 Pfam PF08245 Mur ligase middle domain 40 266 3.8E-15 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 SUPERFAMILY SSF53244 294 434 2.75E-26 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 TIGRFAM TIGR01499 folC: bifunctional protein FolC 18 433 1.0E-110 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 Gene3D G3DSA:3.40.1190.10 7 293 3.0E-98 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 SUPERFAMILY SSF53623 10 290 3.77E-88 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 37 60 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 Pfam PF02875 Mur ligase family, glutamate ligase domain 293 368 6.6E-11 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFR_07585 a443f18e2c511740494c4f314d6896ef 435 PIRSF PIRSF001563 1 435 2.0E-116 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFR_04955 0154e75fc0f849850cce2ce7eac6e951 372 SMART SM01240 15 370 1.8E-17 T 12-10-2018 AFR_04955 0154e75fc0f849850cce2ce7eac6e951 372 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 369 4.9E-168 T 12-10-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 AFR_04955 0154e75fc0f849850cce2ce7eac6e951 372 Gene3D G3DSA:3.20.20.70 16 371 6.7E-88 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_04955 0154e75fc0f849850cce2ce7eac6e951 372 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 17 298 5.0E-32 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 AFR_04955 0154e75fc0f849850cce2ce7eac6e951 372 SUPERFAMILY SSF51412 11 369 6.02E-63 T 12-10-2018 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 Gene3D G3DSA:3.30.420.40 168 344 1.7E-95 T 12-10-2018 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 Gene3D G3DSA:3.90.640.10 207 294 1.7E-95 T 12-10-2018 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 SUPERFAMILY SSF53067 171 356 1.02E-34 T 12-10-2018 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 Pfam PF00012 Hsp70 protein 87 357 8.1E-37 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 Gene3D G3DSA:3.30.420.40 10 354 1.7E-95 T 12-10-2018 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 SUPERFAMILY SSF53067 10 159 1.94E-26 T 12-10-2018 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 PRINTS PR00301 70kDa heat shock protein signature 344 364 2.1E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 PRINTS PR00301 70kDa heat shock protein signature 313 329 2.1E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 PRINTS PR00301 70kDa heat shock protein signature 181 191 2.1E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 PRINTS PR00301 70kDa heat shock protein signature 8 21 2.1E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 PRINTS PR00301 70kDa heat shock protein signature 118 138 2.1E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_37055 9fa2e0bf819e63474a9287f39a845ce2 597 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 316 330 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 337 34.247 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 SMART SM00859 2 117 4.4E-41 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 PIRSF PIRSF000148 1 340 3.1E-113 T 12-10-2018 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 SUPERFAMILY SSF55347 126 324 4.12E-61 T 12-10-2018 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 323 3.4E-50 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 Gene3D G3DSA:3.30.360.10 125 324 3.1E-135 T 12-10-2018 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 116 1.3E-32 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 SUPERFAMILY SSF51735 1 153 3.14E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 336 6.2E-130 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 Gene3D G3DSA:3.40.50.720 3 335 3.1E-135 T 12-10-2018 AFR_09010 ab7f6d1cb04005f820f24bc4d49a3d0b 340 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 240 254 - T 12-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_28340 467876709d61b8331609d09f2b6dc175 909 Pfam PF00196 Bacterial regulatory proteins, luxR family 849 902 3.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28340 467876709d61b8331609d09f2b6dc175 909 Pfam PF13191 AAA ATPase domain 4 153 1.6E-15 T 12-10-2018 AFR_28340 467876709d61b8331609d09f2b6dc175 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 848 862 4.9E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28340 467876709d61b8331609d09f2b6dc175 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 878 890 4.9E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28340 467876709d61b8331609d09f2b6dc175 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 862 878 4.9E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28340 467876709d61b8331609d09f2b6dc175 909 Gene3D G3DSA:1.25.40.10 567 837 2.5E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_28340 467876709d61b8331609d09f2b6dc175 909 SUPERFAMILY SSF46894 841 904 4.76E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28340 467876709d61b8331609d09f2b6dc175 909 SUPERFAMILY SSF52540 9 226 2.08E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28340 467876709d61b8331609d09f2b6dc175 909 Gene3D G3DSA:1.10.10.10 845 907 6.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28340 467876709d61b8331609d09f2b6dc175 909 SMART SM00421 845 902 1.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 55 1106 12.625 T 12-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 Pfam PF01336 OB-fold nucleic acid binding domain 1020 1092 9.3E-8 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 SMART SM00481 56 123 1.0E-24 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 350 759 5.4E-139 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 56 943 2.3E-187 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 Pfam PF14579 Helix-hairpin-helix motif 833 940 2.7E-22 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 Gene3D G3DSA:3.20.20.140 22 325 6.1E-77 T 12-10-2018 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 Pfam PF02811 PHP domain 57 230 4.8E-27 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFR_09885 810ecc569a824f7f8912c481a19cf495 1106 SUPERFAMILY SSF89550 55 266 9.29E-22 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 178 196 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 PRINTS PR00599 Methionine aminopeptidase-1 signature 96 112 9.5E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 9.5E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 PRINTS PR00599 Methionine aminopeptidase-1 signature 203 215 9.5E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 PRINTS PR00599 Methionine aminopeptidase-1 signature 172 184 9.5E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 Hamap MF_01974 Methionine aminopeptidase [map]. 8 261 36.536 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 Pfam PF00557 Metallopeptidase family M24 17 249 1.7E-41 T 12-10-2018 IPR000994 Peptidase M24 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 Gene3D G3DSA:3.90.230.10 2 261 9.0E-87 T 12-10-2018 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 8 260 1.5E-79 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_04615 c806425ff78a5b2f861236c732e056b3 284 SUPERFAMILY SSF55920 9 262 4.84E-73 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like AFR_05525 0da0d1306b06e431423168416a9741ee 114 Pfam PF14155 Domain of unknown function (DUF4307) 3 110 5.5E-30 T 12-10-2018 IPR025443 Protein of unknown function DUF4307 AFR_38860 a80a8305b121ff69e364815c74024967 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 218 238 3.3E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFR_38860 a80a8305b121ff69e364815c74024967 241 Gene3D G3DSA:3.40.50.300 5 236 5.0E-57 T 12-10-2018 AFR_38860 a80a8305b121ff69e364815c74024967 241 Pfam PF00005 ABC transporter 30 170 5.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_38860 a80a8305b121ff69e364815c74024967 241 SUPERFAMILY SSF52540 15 236 1.7E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38860 a80a8305b121ff69e364815c74024967 241 SMART SM00382 39 215 1.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_26005 fe726b8ccc7ea81eaef2a634869bc6a5 379 SUPERFAMILY SSF49899 210 336 3.56E-7 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_26005 fe726b8ccc7ea81eaef2a634869bc6a5 379 SMART SM00637 29 127 1.9E-46 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_26005 fe726b8ccc7ea81eaef2a634869bc6a5 379 SUPERFAMILY SSF49384 25 128 2.23E-31 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_26005 fe726b8ccc7ea81eaef2a634869bc6a5 379 Pfam PF00553 Cellulose binding domain 29 127 2.6E-29 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_26005 fe726b8ccc7ea81eaef2a634869bc6a5 379 Gene3D G3DSA:2.60.120.200 163 379 2.6E-64 T 12-10-2018 AFR_26005 fe726b8ccc7ea81eaef2a634869bc6a5 379 Gene3D G3DSA:2.60.40.290 23 129 6.0E-35 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 Gene3D G3DSA:3.40.50.720 1 161 3.8E-44 T 12-10-2018 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 262 6.7E-38 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 SUPERFAMILY SSF48179 158 264 8.5E-36 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 263 26.171 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 SUPERFAMILY SSF51735 3 157 2.91E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 219 241 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 96 1.9E-19 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 263 4.2E-77 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 PIRSF PIRSF000193 1 266 2.6E-72 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFR_09630 b5be04a7b0783a1cd30c5d10edc57c2c 267 Gene3D G3DSA:1.10.3730.10 162 267 3.6E-40 T 12-10-2018 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Gene3D G3DSA:1.10.730.10 19 746 1.2E-300 T 12-10-2018 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 SUPERFAMILY SSF46589 812 876 7.32E-14 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Pfam PF08264 Anticodon-binding domain of tRNA 615 759 1.3E-46 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 SUPERFAMILY SSF50677 208 347 2.49E-53 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 PRINTS PR00986 Valyl-tRNA synthetase signature 52 63 7.7E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 PRINTS PR00986 Valyl-tRNA synthetase signature 484 502 7.7E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 PRINTS PR00986 Valyl-tRNA synthetase signature 453 474 7.7E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 PRINTS PR00986 Valyl-tRNA synthetase signature 244 261 7.7E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 PRINTS PR00986 Valyl-tRNA synthetase signature 359 372 7.7E-39 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Gene3D G3DSA:3.90.740.10 191 355 1.2E-300 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Hamap MF_02004 Valine--tRNA ligase [valS]. 18 877 15.265 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 812 876 1.3E-15 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 31 571 6.5E-190 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Gene3D G3DSA:3.40.50.620 38 534 1.2E-300 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 Gene3D G3DSA:1.10.287.380 805 877 2.4E-16 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 SUPERFAMILY SSF52374 16 583 3.49E-137 T 12-10-2018 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 SUPERFAMILY SSF47323 584 824 8.72E-61 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_07580 0b93df1fd93f3b5ea0fdb6956298d857 879 TIGRFAM TIGR00422 valS: valine--tRNA ligase 20 856 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 Pfam PF01494 FAD binding domain 10 331 7.4E-21 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 2.1E-11 T 12-10-2018 AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 2.1E-11 T 12-10-2018 AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 2.1E-11 T 12-10-2018 AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 2.1E-11 T 12-10-2018 AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 Gene3D G3DSA:3.50.50.60 12 352 1.8E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 SUPERFAMILY SSF51905 9 359 1.77E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27420 257d0ed12f46fc0db00bc6c2c4b962e6 388 Gene3D G3DSA:3.30.9.50 45 280 1.8E-64 T 12-10-2018 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Pfam PF08326 Acetyl-CoA carboxylase, central region 1015 1207 2.1E-22 T 12-10-2018 IPR013537 Acetyl-CoA carboxylase, central domain GO:0003989|GO:0005524|GO:0006633 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-163765|Reactome: R-HSA-196780|Reactome: R-HSA-200425|Reactome: R-HSA-2426168 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Gene3D G3DSA:3.90.226.10 1513 1826 1.1E-57 T 12-10-2018 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 SUPERFAMILY SSF56059 88 334 3.01E-59 T 12-10-2018 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 SUPERFAMILY SSF51246 335 450 1.15E-35 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 SUPERFAMILY SSF52096 1278 1498 8.53E-21 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 SUPERFAMILY SSF52440 2 118 3.36E-33 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 115 5.5E-33 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Pfam PF02785 Biotin carboxylase C-terminal domain 340 449 8.7E-35 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Gene3D G3DSA:3.30.470.130 1 453 1.3E-169 T 12-10-2018 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Pfam PF01039 Carboxyl transferase domain 1320 1821 4.0E-29 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 SMART SM00878 340 448 2.6E-50 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Gene3D G3DSA:2.40.50.100 581 655 4.2E-16 T 12-10-2018 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 SUPERFAMILY SSF51230 580 655 2.09E-15 T 12-10-2018 IPR011053 Single hybrid motif AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Pfam PF00364 Biotin-requiring enzyme 589 654 1.2E-9 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Gene3D G3DSA:3.90.226.10 1253 1504 9.0E-34 T 12-10-2018 AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 SUPERFAMILY SSF52096 1548 1822 3.18E-38 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_34255 1f9535d9c32ce6548c65bc23c99ce110 1826 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 328 5.6E-61 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 Gene3D G3DSA:3.10.150.10 1 121 3.0E-40 T 12-10-2018 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 PIRSF PIRSF000804 1 376 1.3E-86 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 1.4E-33 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 247 1.6E-27 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 SUPERFAMILY SSF55979 251 375 4.4E-26 T 12-10-2018 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 SUPERFAMILY SSF55979 1 118 7.68E-23 T 12-10-2018 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 Gene3D G3DSA:3.10.150.10 253 377 2.1E-35 T 12-10-2018 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 SMART SM00480 17 371 7.8E-99 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 SUPERFAMILY SSF55979 126 249 9.42E-17 T 12-10-2018 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 7.5E-82 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 373 4.6E-26 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFR_00010 fc2fcc9b2c81b253856f12877c65098d 377 Gene3D G3DSA:3.10.150.10 123 251 2.4E-30 T 12-10-2018 AFR_37945 fff2f6fedca64b53e3141cd60a877d48 238 Gene3D G3DSA:1.10.10.10 141 238 4.9E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37945 fff2f6fedca64b53e3141cd60a877d48 238 Gene3D G3DSA:3.40.50.2300 2 140 1.8E-38 T 12-10-2018 AFR_37945 fff2f6fedca64b53e3141cd60a877d48 238 SUPERFAMILY SSF52172 12 188 1.45E-41 T 12-10-2018 IPR011006 CheY-like superfamily AFR_37945 fff2f6fedca64b53e3141cd60a877d48 238 Pfam PF00072 Response regulator receiver domain 16 125 2.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_37945 fff2f6fedca64b53e3141cd60a877d48 238 SMART SM00448 13 124 7.4E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_37945 fff2f6fedca64b53e3141cd60a877d48 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 233 2.7E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_37945 fff2f6fedca64b53e3141cd60a877d48 238 SMART SM00862 159 233 9.2E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 10 468 2.1E-220 T 12-10-2018 IPR014065 tRNA adenylyltransferase AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 SMART SM00471 258 421 0.0019 T 12-10-2018 IPR003607 HD/PDEase domain AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 Gene3D G3DSA:3.30.460.10 20 159 3.8E-36 T 12-10-2018 AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 Pfam PF01743 Poly A polymerase head domain 37 160 3.4E-32 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 SUPERFAMILY SSF81891 158 471 1.06E-61 T 12-10-2018 AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 Pfam PF01966 HD domain 262 363 3.9E-13 T 12-10-2018 IPR006674 HD domain AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 TIGRFAM TIGR00277 HDIG: HDIG domain 259 337 9.3E-13 T 12-10-2018 IPR006675 HDIG domain AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 188 246 6.7E-17 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 SUPERFAMILY SSF81301 19 156 1.0E-35 T 12-10-2018 AFR_42900 4d3ec1e41d1c1f114fefa3c3b328c3ad 476 Gene3D G3DSA:1.10.3090.10 160 457 9.3E-43 T 12-10-2018 AFR_38360 788632bcf5d7b5050405774b0a393578 80 Gene3D G3DSA:3.40.30.10 1 80 1.4E-24 T 12-10-2018 AFR_38360 788632bcf5d7b5050405774b0a393578 80 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 2 76 2.5E-36 T 12-10-2018 IPR011915 Glutaredoxin-like protein, actinobacteria AFR_38360 788632bcf5d7b5050405774b0a393578 80 ProSitePatterns PS00194 Thioredoxin family active site. 2 20 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFR_38360 788632bcf5d7b5050405774b0a393578 80 SUPERFAMILY SSF52833 1 69 4.92E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_38360 788632bcf5d7b5050405774b0a393578 80 Pfam PF00462 Glutaredoxin 3 59 4.3E-14 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 Gene3D G3DSA:3.40.50.300 309 561 1.2E-79 T 12-10-2018 AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 Pfam PF00664 ABC transporter transmembrane region 2 270 1.5E-45 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 Gene3D G3DSA:1.20.1560.10 1 299 9.6E-80 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 Pfam PF00005 ABC transporter 334 481 3.7E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 SMART SM00382 343 529 8.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 SUPERFAMILY SSF90123 2 302 2.88E-70 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 SUPERFAMILY SSF52540 308 553 3.37E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33440 36f8ec8ee894859260c30e5959ec0fdb 561 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 Gene3D G3DSA:3.40.50.720 10 319 1.5E-116 T 12-10-2018 AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 234 250 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 SUPERFAMILY SSF52283 9 136 2.98E-22 T 12-10-2018 AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 123 295 2.8E-54 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 157 184 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 Gene3D G3DSA:3.40.50.720 116 311 1.5E-116 T 12-10-2018 AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 34 321 1.3E-11 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFR_32155 eb15b10e2925ed2fd482b2dd2f6d50a9 327 SUPERFAMILY SSF51735 117 295 1.24E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07850 9f70dbf82f09db33a75bb8b5e1b244ed 244 Gene3D G3DSA:2.40.240.20 1 69 9.5E-21 T 12-10-2018 AFR_07850 9f70dbf82f09db33a75bb8b5e1b244ed 244 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 17 242 4.6E-35 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFR_07850 9f70dbf82f09db33a75bb8b5e1b244ed 244 Gene3D G3DSA:3.40.1280.10 73 244 3.1E-53 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFR_07850 9f70dbf82f09db33a75bb8b5e1b244ed 244 SUPERFAMILY SSF75217 74 244 1.15E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFR_07850 9f70dbf82f09db33a75bb8b5e1b244ed 244 PIRSF PIRSF015601 2 244 1.1E-47 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFR_07850 9f70dbf82f09db33a75bb8b5e1b244ed 244 SUPERFAMILY SSF88697 5 67 1.07E-11 T 12-10-2018 IPR015947 PUA-like superfamily AFR_07850 9f70dbf82f09db33a75bb8b5e1b244ed 244 Pfam PF04452 RNA methyltransferase 18 239 2.9E-59 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFR_03960 fb81e58c5881576d30cdd2b998d9e666 719 Gene3D G3DSA:3.20.20.80 95 488 1.6E-6 T 12-10-2018 AFR_03960 fb81e58c5881576d30cdd2b998d9e666 719 SUPERFAMILY SSF51445 94 441 2.11E-15 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_11365 6e1883c4bf8646282ca3ef7f297add57 277 Gene3D G3DSA:3.20.20.30 8 260 9.1E-58 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_11365 6e1883c4bf8646282ca3ef7f297add57 277 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 248 2.1E-73 T 12-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted AFR_11365 6e1883c4bf8646282ca3ef7f297add57 277 Pfam PF00296 Luciferase-like monooxygenase 18 222 1.1E-44 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_11365 6e1883c4bf8646282ca3ef7f297add57 277 SUPERFAMILY SSF51679 1 267 1.96E-49 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_30900 43303a094171014044babd61b7e56102 249 SUPERFAMILY SSF53474 20 245 8.18E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_30900 43303a094171014044babd61b7e56102 249 Gene3D G3DSA:3.40.50.1820 18 246 1.4E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 SUPERFAMILY SSF55545 11 145 6.43E-29 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 13 142 5.8E-22 T 12-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 140 157 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 445 462 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 230 247 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 278 296 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 98 118 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 300 313 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 427 443 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 PRINTS PR00738 Glycosyl hydrolase family 20 signature 169 190 6.7E-44 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 Gene3D G3DSA:3.20.20.80 138 496 1.2E-132 T 12-10-2018 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 SUPERFAMILY SSF51445 146 492 1.64E-103 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 Gene3D G3DSA:3.30.379.10 7 137 6.0E-34 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_06925 e0c5b52d167778f8fd619ec1ddc466a3 498 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 146 463 3.8E-81 T 12-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 AFR_35050 357da8f79db7310cf6ca084f6237a400 311 SUPERFAMILY SSF51735 1 247 1.22E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35050 357da8f79db7310cf6ca084f6237a400 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 3.0E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35050 357da8f79db7310cf6ca084f6237a400 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 16 3.0E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35050 357da8f79db7310cf6ca084f6237a400 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.0E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35050 357da8f79db7310cf6ca084f6237a400 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.0E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35050 357da8f79db7310cf6ca084f6237a400 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.0E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35050 357da8f79db7310cf6ca084f6237a400 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 3.0E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35050 357da8f79db7310cf6ca084f6237a400 311 Pfam PF00106 short chain dehydrogenase 1 186 1.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35050 357da8f79db7310cf6ca084f6237a400 311 Gene3D G3DSA:3.40.50.720 1 238 1.1E-54 T 12-10-2018 AFR_38625 78d696454a5723f9891a2192fbe0e4be 321 SUPERFAMILY SSF53335 36 207 8.34E-11 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_38625 78d696454a5723f9891a2192fbe0e4be 321 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 17 317 6.0E-111 T 12-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 AFR_38625 78d696454a5723f9891a2192fbe0e4be 321 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 4 320 56.9 T 12-10-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 AFR_38625 78d696454a5723f9891a2192fbe0e4be 321 Gene3D G3DSA:3.40.50.150 44 218 1.1E-53 T 12-10-2018 AFR_38625 78d696454a5723f9891a2192fbe0e4be 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 17 319 3.2E-110 T 12-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent AFR_38625 78d696454a5723f9891a2192fbe0e4be 321 PIRSF PIRSF018005 2 321 7.6E-125 T 12-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 AFR_07555 a39671487cb42fc2f9c0345a27a97c83 168 Pfam PF08445 FR47-like protein 104 155 1.4E-5 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_07555 a39671487cb42fc2f9c0345a27a97c83 168 Gene3D G3DSA:3.40.630.30 2 164 1.1E-7 T 12-10-2018 AFR_07555 a39671487cb42fc2f9c0345a27a97c83 168 SUPERFAMILY SSF55729 98 158 1.12E-8 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_04135 e106eb94e8298d5704a3067e79e753df 656 SUPERFAMILY SSF141571 2 176 2.55E-6 T 12-10-2018 AFR_04710 12dc1ae0679bdd5f7f7b4beeb3da1e0f 189 SUPERFAMILY SSF51391 5 183 1.44E-33 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_04710 12dc1ae0679bdd5f7f7b4beeb3da1e0f 189 Gene3D G3DSA:3.20.20.70 3 185 2.5E-35 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_04710 12dc1ae0679bdd5f7f7b4beeb3da1e0f 189 Pfam PF02581 Thiamine monophosphate synthase 7 58 2.9E-5 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_04710 12dc1ae0679bdd5f7f7b4beeb3da1e0f 189 Pfam PF02581 Thiamine monophosphate synthase 89 167 2.9E-12 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_07305 5d4bf8185f129186eb7ad7d8f59edab8 449 Gene3D G3DSA:3.30.70.360 202 362 1.9E-118 T 12-10-2018 AFR_07305 5d4bf8185f129186eb7ad7d8f59edab8 449 Pfam PF07687 Peptidase dimerisation domain 194 343 3.8E-18 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFR_07305 5d4bf8185f129186eb7ad7d8f59edab8 449 Pfam PF01546 Peptidase family M20/M25/M40 85 436 5.3E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_07305 5d4bf8185f129186eb7ad7d8f59edab8 449 SUPERFAMILY SSF53187 7 445 3.83E-56 T 12-10-2018 AFR_07305 5d4bf8185f129186eb7ad7d8f59edab8 449 Gene3D G3DSA:3.40.630.10 22 431 1.9E-118 T 12-10-2018 AFR_16620 ce39790c2eebf563042f3bde8cd2e35f 468 Gene3D G3DSA:3.40.309.10 248 429 5.0E-121 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_16620 ce39790c2eebf563042f3bde8cd2e35f 468 Pfam PF00171 Aldehyde dehydrogenase family 12 459 6.6E-112 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_16620 ce39790c2eebf563042f3bde8cd2e35f 468 SUPERFAMILY SSF53720 2 462 3.27E-122 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_16620 ce39790c2eebf563042f3bde8cd2e35f 468 Gene3D G3DSA:3.40.605.10 8 457 5.0E-121 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_23090 385efe2fcbc5473ba3fc4b73b284c0b9 113 Pfam PF12680 SnoaL-like domain 8 108 2.9E-14 T 12-10-2018 IPR037401 SnoaL-like domain AFR_23090 385efe2fcbc5473ba3fc4b73b284c0b9 113 Gene3D G3DSA:3.10.450.50 3 111 3.6E-17 T 12-10-2018 AFR_23090 385efe2fcbc5473ba3fc4b73b284c0b9 113 SUPERFAMILY SSF54427 1 109 7.45E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_10575 208e009f3e3dfad002326a3d702b65d9 263 SUPERFAMILY SSF51351 5 257 1.96E-92 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10575 208e009f3e3dfad002326a3d702b65d9 263 ProSitePatterns PS00171 Triosephosphate isomerase active site. 173 183 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10575 208e009f3e3dfad002326a3d702b65d9 263 Pfam PF00121 Triosephosphate isomerase 9 255 3.7E-91 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10575 208e009f3e3dfad002326a3d702b65d9 263 Gene3D G3DSA:3.20.20.70 4 262 4.2E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10575 208e009f3e3dfad002326a3d702b65d9 263 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 6 257 60.513 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10575 208e009f3e3dfad002326a3d702b65d9 263 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 10 249 8.6E-59 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_15235 d40653ceb722115299ee422dc41b1e85 320 SUPERFAMILY SSF53474 7 316 6.43E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15235 d40653ceb722115299ee422dc41b1e85 320 Gene3D G3DSA:3.40.50.1820 3 319 3.4E-80 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15235 d40653ceb722115299ee422dc41b1e85 320 Pfam PF07859 alpha/beta hydrolase fold 85 291 1.9E-50 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 ProSitePatterns PS00674 AAA-protein family signature. 612 630 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Gene3D G3DSA:3.40.50.300 472 728 6.1E-87 T 12-10-2018 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Gene3D G3DSA:1.10.8.60 383 471 2.0E-18 T 12-10-2018 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 7 89 1.8E-8 T 12-10-2018 IPR003338 CDC48, N-terminal subdomain AFR_40925 66c828478fc9da78642aeaaba1102af2 737 SMART SM01073 6 90 8.6E-12 T 12-10-2018 IPR003338 CDC48, N-terminal subdomain AFR_40925 66c828478fc9da78642aeaaba1102af2 737 SMART SM00382 254 383 2.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_40925 66c828478fc9da78642aeaaba1102af2 737 SMART SM00382 507 644 2.2E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 511 641 4.4E-43 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 258 380 4.1E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 SUPERFAMILY SSF52540 214 455 3.98E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40925 66c828478fc9da78642aeaaba1102af2 737 SUPERFAMILY SSF50692 7 88 5.8E-8 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Gene3D G3DSA:3.40.50.300 209 382 1.7E-23 T 12-10-2018 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Gene3D G3DSA:1.10.8.60 643 715 6.1E-87 T 12-10-2018 AFR_40925 66c828478fc9da78642aeaaba1102af2 737 SUPERFAMILY SSF52540 470 715 2.82E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40925 66c828478fc9da78642aeaaba1102af2 737 Gene3D G3DSA:2.40.40.20 2 89 2.2E-7 T 12-10-2018 AFR_29885 d26013311b57cc3e37d325b51c8460f8 800 Pfam PF07282 Putative transposase DNA-binding domain 298 365 9.0E-19 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_29885 d26013311b57cc3e37d325b51c8460f8 800 Pfam PF00296 Luciferase-like monooxygenase 486 763 2.1E-38 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_29885 d26013311b57cc3e37d325b51c8460f8 800 Gene3D G3DSA:3.20.20.30 465 794 4.3E-90 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_29885 d26013311b57cc3e37d325b51c8460f8 800 Pfam PF01385 Probable transposase 187 283 2.5E-21 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFR_29885 d26013311b57cc3e37d325b51c8460f8 800 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 470 790 1.2E-117 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 AFR_29885 d26013311b57cc3e37d325b51c8460f8 800 SUPERFAMILY SSF51679 468 790 1.77E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_29885 d26013311b57cc3e37d325b51c8460f8 800 Pfam PF12323 Helix-turn-helix domain 2 44 1.0E-14 T 12-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFR_26215 7d46ae4ca7a35a28c53b4ea39e48ec04 515 Gene3D G3DSA:3.40.50.12780 1 417 2.7E-118 T 12-10-2018 AFR_26215 7d46ae4ca7a35a28c53b4ea39e48ec04 515 Gene3D G3DSA:3.30.300.310 420 515 3.0E-31 T 12-10-2018 AFR_26215 7d46ae4ca7a35a28c53b4ea39e48ec04 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 508 2.0E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_26215 7d46ae4ca7a35a28c53b4ea39e48ec04 515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_26215 7d46ae4ca7a35a28c53b4ea39e48ec04 515 Pfam PF00501 AMP-binding enzyme 8 424 8.6E-108 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_26215 7d46ae4ca7a35a28c53b4ea39e48ec04 515 SUPERFAMILY SSF56801 7 514 2.62E-154 T 12-10-2018 AFR_11115 745a0ceeeea0d1dd4dea5f695e69b753 437 SUPERFAMILY SSF56601 12 314 2.18E-71 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_11115 745a0ceeeea0d1dd4dea5f695e69b753 437 Pfam PF00144 Beta-lactamase 17 313 4.1E-53 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_11115 745a0ceeeea0d1dd4dea5f695e69b753 437 Gene3D G3DSA:3.40.710.10 6 317 4.0E-75 T 12-10-2018 AFR_38795 517143bd231ac258b38fe19ba403e441 515 Gene3D G3DSA:1.25.40.10 16 326 1.2E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_38795 517143bd231ac258b38fe19ba403e441 515 SUPERFAMILY SSF55073 368 512 2.9E-36 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_38795 517143bd231ac258b38fe19ba403e441 515 Pfam PF00990 Diguanylate cyclase, GGDEF domain 363 511 6.0E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_38795 517143bd231ac258b38fe19ba403e441 515 SUPERFAMILY SSF48452 177 291 1.9E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_38795 517143bd231ac258b38fe19ba403e441 515 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 362 513 2.0E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_38795 517143bd231ac258b38fe19ba403e441 515 SUPERFAMILY SSF48452 60 210 2.24E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_38795 517143bd231ac258b38fe19ba403e441 515 SMART SM00267 352 515 6.9E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_38795 517143bd231ac258b38fe19ba403e441 515 Gene3D G3DSA:3.30.70.270 359 515 3.4E-43 T 12-10-2018 AFR_02350 e20d677cc3b084e3fb6383e2e23c921c 566 Gene3D G3DSA:2.60.120.200 403 565 1.0E-25 T 12-10-2018 AFR_02350 e20d677cc3b084e3fb6383e2e23c921c 566 SUPERFAMILY SSF49899 199 368 1.86E-8 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_02350 e20d677cc3b084e3fb6383e2e23c921c 566 SMART SM00560 427 554 0.003 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_02350 e20d677cc3b084e3fb6383e2e23c921c 566 Gene3D G3DSA:2.60.120.560 195 355 5.7E-22 T 12-10-2018 AFR_02350 e20d677cc3b084e3fb6383e2e23c921c 566 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 411 556 7.5E-21 T 12-10-2018 AFR_02350 e20d677cc3b084e3fb6383e2e23c921c 566 SUPERFAMILY SSF49899 367 562 4.14E-27 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_37185 364cada920309b3e87dccedf74ebeda0 370 Gene3D G3DSA:3.40.50.2300 148 348 5.1E-90 T 12-10-2018 AFR_37185 364cada920309b3e87dccedf74ebeda0 370 SUPERFAMILY SSF53822 44 318 1.02E-50 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_37185 364cada920309b3e87dccedf74ebeda0 370 Gene3D G3DSA:3.40.50.2300 45 331 5.1E-90 T 12-10-2018 AFR_37185 364cada920309b3e87dccedf74ebeda0 370 Pfam PF13407 Periplasmic binding protein domain 48 309 8.7E-49 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_18595 fd898a4817c62941e092f6dc807afdca 204 SUPERFAMILY SSF48498 91 202 4.73E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_18595 fd898a4817c62941e092f6dc807afdca 204 SUPERFAMILY SSF46689 19 79 4.42E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_18595 fd898a4817c62941e092f6dc807afdca 204 Gene3D G3DSA:1.10.10.60 14 68 3.4E-19 T 12-10-2018 AFR_18595 fd898a4817c62941e092f6dc807afdca 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 74 5.1E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18595 fd898a4817c62941e092f6dc807afdca 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 86 198 1.6E-19 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_18595 fd898a4817c62941e092f6dc807afdca 204 Gene3D G3DSA:1.10.357.10 69 204 1.0E-24 T 12-10-2018 AFR_03830 58f88da8d5a966e238cad5d315a64210 78 SMART SM00421 3 60 5.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03830 58f88da8d5a966e238cad5d315a64210 78 SUPERFAMILY SSF46894 4 57 3.37E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_03830 58f88da8d5a966e238cad5d315a64210 78 Gene3D G3DSA:1.10.10.10 2 74 2.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03830 58f88da8d5a966e238cad5d315a64210 78 Pfam PF00196 Bacterial regulatory proteins, luxR family 5 56 4.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03830 58f88da8d5a966e238cad5d315a64210 78 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 20 36 4.0E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03830 58f88da8d5a966e238cad5d315a64210 78 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 6 20 4.0E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14435 47f98bd402245de4d438c5c3176a754a 404 Pfam PF07690 Major Facilitator Superfamily 226 397 2.6E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_14435 47f98bd402245de4d438c5c3176a754a 404 Gene3D G3DSA:1.20.1250.20 14 194 6.0E-16 T 12-10-2018 AFR_14435 47f98bd402245de4d438c5c3176a754a 404 Gene3D G3DSA:1.20.1250.20 218 403 5.8E-24 T 12-10-2018 AFR_14435 47f98bd402245de4d438c5c3176a754a 404 SUPERFAMILY SSF103473 13 401 3.01E-42 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 Gene3D G3DSA:3.40.50.1370 133 282 8.5E-97 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 145 7.3E-43 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 305 41.184 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 4.6E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 4.6E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 4.6E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 4.6E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 4.6E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 132 149 4.6E-31 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 152 302 5.4E-26 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 SUPERFAMILY SSF53671 2 305 1.31E-97 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 303 9.4E-99 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 Gene3D G3DSA:3.40.50.1370 7 298 8.5E-97 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 6.4E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 133 144 6.4E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 6.4E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_30630 ddcb8f2610bc9d836d26b747e0887296 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 6.4E-21 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFR_15945 ab314a4058d29ee53e61407627d5afba 521 Gene3D G3DSA:3.30.300.30 419 521 5.1E-27 T 12-10-2018 AFR_15945 ab314a4058d29ee53e61407627d5afba 521 Pfam PF00501 AMP-binding enzyme 11 425 6.1E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_15945 ab314a4058d29ee53e61407627d5afba 521 TIGRFAM TIGR03098 ligase_PEP_1: acyl-CoA ligase (AMP-forming), exosortase A-associated 5 518 3.5E-231 T 12-10-2018 IPR017529 Acyl-CoA ligase (AMP-forming), exosortase system type 1 associated AFR_15945 ab314a4058d29ee53e61407627d5afba 521 SUPERFAMILY SSF56801 4 519 1.7E-144 T 12-10-2018 AFR_15945 ab314a4058d29ee53e61407627d5afba 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 509 1.2E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_15945 ab314a4058d29ee53e61407627d5afba 521 Gene3D G3DSA:3.40.50.12780 2 418 3.6E-107 T 12-10-2018 AFR_15945 ab314a4058d29ee53e61407627d5afba 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_17220 e97175417f9da99945514535eb212fcb 209 Gene3D G3DSA:3.40.50.360 1 190 4.7E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_17220 e97175417f9da99945514535eb212fcb 209 SUPERFAMILY SSF52218 3 169 8.2E-29 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_17220 e97175417f9da99945514535eb212fcb 209 Pfam PF03358 NADPH-dependent FMN reductase 2 130 3.8E-23 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_37650 4515880f4adef3dd9b083452ca71bc73 300 Gene3D G3DSA:3.40.50.1820 11 269 4.8E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_37650 4515880f4adef3dd9b083452ca71bc73 300 ProSitePatterns PS00099 Thiolases active site. 107 120 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 AFR_37650 4515880f4adef3dd9b083452ca71bc73 300 Gene3D G3DSA:1.10.10.800 140 213 4.8E-65 T 12-10-2018 AFR_37650 4515880f4adef3dd9b083452ca71bc73 300 SUPERFAMILY SSF53474 4 289 4.55E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_37650 4515880f4adef3dd9b083452ca71bc73 300 Pfam PF12146 Serine aminopeptidase, S33 50 264 8.3E-18 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFR_36305 75ddbe3b50f17ef7f690670aa241ac20 279 Pfam PF00717 Peptidase S24-like 36 78 8.7E-9 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFR_36305 75ddbe3b50f17ef7f690670aa241ac20 279 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 16 211 7.7E-44 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_36305 75ddbe3b50f17ef7f690670aa241ac20 279 SUPERFAMILY SSF51306 28 217 3.14E-49 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFR_36305 75ddbe3b50f17ef7f690670aa241ac20 279 Pfam PF10502 Signal peptidase, peptidase S26 113 207 9.1E-9 T 12-10-2018 IPR019533 Peptidase S26 AFR_36305 75ddbe3b50f17ef7f690670aa241ac20 279 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 30 46 4.0E-20 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_36305 75ddbe3b50f17ef7f690670aa241ac20 279 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 113 125 4.0E-20 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_36305 75ddbe3b50f17ef7f690670aa241ac20 279 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 171 190 4.0E-20 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_41240 3cc3b24dcf6e245d2387bcb933ee1cde 305 SUPERFAMILY SSF161098 50 292 6.41E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41240 3cc3b24dcf6e245d2387bcb933ee1cde 305 SUPERFAMILY SSF160964 5 40 4.32E-6 T 12-10-2018 AFR_41240 3cc3b24dcf6e245d2387bcb933ee1cde 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 291 4.0E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_41240 3cc3b24dcf6e245d2387bcb933ee1cde 305 Gene3D G3DSA:1.10.3720.10 46 301 9.8E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11570 df209d9baa61cd676db6a2a329f777d3 124 Pfam PF00072 Response regulator receiver domain 4 116 7.8E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11570 df209d9baa61cd676db6a2a329f777d3 124 SMART SM00448 2 115 5.1E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11570 df209d9baa61cd676db6a2a329f777d3 124 Gene3D G3DSA:3.40.50.12740 2 123 1.3E-45 T 12-10-2018 AFR_11570 df209d9baa61cd676db6a2a329f777d3 124 SUPERFAMILY SSF52172 2 122 4.84E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFR_32665 92be43fffeb568627ba6ccdaa88465f4 314 Gene3D G3DSA:2.60.200.40 120 275 6.3E-36 T 12-10-2018 AFR_32665 92be43fffeb568627ba6ccdaa88465f4 314 Pfam PF00781 Diacylglycerol kinase catalytic domain 20 118 1.2E-18 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFR_32665 92be43fffeb568627ba6ccdaa88465f4 314 Gene3D G3DSA:3.40.50.10330 1 119 2.7E-23 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_32665 92be43fffeb568627ba6ccdaa88465f4 314 SUPERFAMILY SSF111331 2 285 2.62E-61 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_29575 8e45ba1cdcd9b74629a186f78d4e35b4 708 SMART SM00487 19 224 4.6E-33 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_29575 8e45ba1cdcd9b74629a186f78d4e35b4 708 Pfam PF00270 DEAD/DEAH box helicase 25 193 7.8E-25 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_29575 8e45ba1cdcd9b74629a186f78d4e35b4 708 SUPERFAMILY SSF52540 33 355 2.99E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29575 8e45ba1cdcd9b74629a186f78d4e35b4 708 Gene3D G3DSA:3.40.50.300 9 211 6.8E-44 T 12-10-2018 AFR_29575 8e45ba1cdcd9b74629a186f78d4e35b4 708 SMART SM00490 271 352 1.7E-22 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_29575 8e45ba1cdcd9b74629a186f78d4e35b4 708 Pfam PF00271 Helicase conserved C-terminal domain 252 350 1.5E-19 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_29575 8e45ba1cdcd9b74629a186f78d4e35b4 708 Gene3D G3DSA:3.40.50.300 239 373 5.0E-27 T 12-10-2018 AFR_32750 20cb5f92235a45f150ffecf3e44fd651 236 SMART SM00382 34 201 8.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_32750 20cb5f92235a45f150ffecf3e44fd651 236 Gene3D G3DSA:3.40.50.300 7 226 3.2E-58 T 12-10-2018 AFR_32750 20cb5f92235a45f150ffecf3e44fd651 236 SUPERFAMILY SSF52540 11 213 2.66E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32750 20cb5f92235a45f150ffecf3e44fd651 236 Pfam PF00005 ABC transporter 25 152 1.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_32750 20cb5f92235a45f150ffecf3e44fd651 236 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_32935 48356bb84e1f2414f2161a3057077d3b 695 Gene3D G3DSA:3.40.80.10 197 396 3.6E-53 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_32935 48356bb84e1f2414f2161a3057077d3b 695 SUPERFAMILY SSF55846 203 392 2.45E-45 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_32935 48356bb84e1f2414f2161a3057077d3b 695 Gene3D G3DSA:2.60.120.260 592 686 1.7E-5 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32935 48356bb84e1f2414f2161a3057077d3b 695 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 226 378 2.7E-14 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_32935 48356bb84e1f2414f2161a3057077d3b 695 SMART SM00701 203 351 1.9E-42 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFR_04270 775f603235e90bcd738e5f68a1d6e88f 515 Pfam PF00361 Proton-conducting membrane transporter 155 440 3.2E-71 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04270 775f603235e90bcd738e5f68a1d6e88f 515 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 20 510 5.0E-140 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04270 775f603235e90bcd738e5f68a1d6e88f 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 180 3.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04270 775f603235e90bcd738e5f68a1d6e88f 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 261 285 3.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04270 775f603235e90bcd738e5f68a1d6e88f 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 191 215 3.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04270 775f603235e90bcd738e5f68a1d6e88f 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 401 427 3.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04270 775f603235e90bcd738e5f68a1d6e88f 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 349 368 3.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27625 6bb7ceaaec8e5ca81757d09eaee57194 412 Gene3D G3DSA:1.10.10.10 23 97 9.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27625 6bb7ceaaec8e5ca81757d09eaee57194 412 SUPERFAMILY SSF46785 31 95 1.55E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27625 6bb7ceaaec8e5ca81757d09eaee57194 412 Pfam PF00480 ROK family 107 398 5.0E-37 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_27625 6bb7ceaaec8e5ca81757d09eaee57194 412 Gene3D G3DSA:3.30.420.40 111 394 2.6E-51 T 12-10-2018 AFR_27625 6bb7ceaaec8e5ca81757d09eaee57194 412 SUPERFAMILY SSF53067 226 404 6.29E-39 T 12-10-2018 AFR_27625 6bb7ceaaec8e5ca81757d09eaee57194 412 Gene3D G3DSA:3.30.420.40 225 384 2.6E-51 T 12-10-2018 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 Gene3D G3DSA:3.40.47.10 125 386 5.2E-131 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 Gene3D G3DSA:3.40.47.10 6 289 5.2E-131 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.5E-130 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 SUPERFAMILY SSF53901 1 266 5.26E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 Pfam PF00108 Thiolase, N-terminal domain 5 261 4.3E-61 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 SUPERFAMILY SSF53901 270 391 1.73E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 Pfam PF02803 Thiolase, C-terminal domain 270 391 1.7E-40 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFR_19520 70e20a438059f1048d1f5fbb54e2087a 393 PIRSF PIRSF000429 1 393 6.9E-114 T 12-10-2018 IPR002155 Thiolase GO:0016747 AFR_07360 4e7d40747e5d09bc166a2fab7d429892 322 Pfam PF00155 Aminotransferase class I and II 10 312 3.1E-32 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_07360 4e7d40747e5d09bc166a2fab7d429892 322 Gene3D G3DSA:3.90.1150.10 222 314 2.9E-72 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_07360 4e7d40747e5d09bc166a2fab7d429892 322 SUPERFAMILY SSF53383 3 317 1.22E-55 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_07360 4e7d40747e5d09bc166a2fab7d429892 322 Gene3D G3DSA:3.40.640.10 1 221 2.9E-72 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_07360 4e7d40747e5d09bc166a2fab7d429892 322 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 173 186 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFR_31575 330615fc2892835f4d99d8fef4a92cfa 129 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 75 128 2.0E-11 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_31575 330615fc2892835f4d99d8fef4a92cfa 129 SMART SM01234 61 128 7.3E-21 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_31575 330615fc2892835f4d99d8fef4a92cfa 129 Pfam PF01809 Haemolytic domain 64 128 9.0E-22 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_31575 330615fc2892835f4d99d8fef4a92cfa 129 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 66 129 1.3E-17 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_03050 d2fd4172b15dc4574c03344bc75ee1ec 329 Gene3D G3DSA:3.40.50.300 2 233 6.5E-62 T 12-10-2018 AFR_03050 d2fd4172b15dc4574c03344bc75ee1ec 329 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_03050 d2fd4172b15dc4574c03344bc75ee1ec 329 SMART SM00382 31 222 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03050 d2fd4172b15dc4574c03344bc75ee1ec 329 Pfam PF00005 ABC transporter 22 165 5.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03050 d2fd4172b15dc4574c03344bc75ee1ec 329 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 310 2.7E-109 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFR_03050 d2fd4172b15dc4574c03344bc75ee1ec 329 SUPERFAMILY SSF52540 5 225 3.45E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14425 74b9e29b156dcc12111f74fd46796395 271 SUPERFAMILY SSF56176 1 159 1.64E-30 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_14425 74b9e29b156dcc12111f74fd46796395 271 Gene3D G3DSA:3.30.465.10 43 159 6.7E-29 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_14425 74b9e29b156dcc12111f74fd46796395 271 Gene3D G3DSA:3.30.390.50 165 270 1.3E-13 T 12-10-2018 AFR_14425 74b9e29b156dcc12111f74fd46796395 271 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 178 266 1.3E-7 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_14425 74b9e29b156dcc12111f74fd46796395 271 Gene3D G3DSA:3.30.43.10 1 42 3.3E-6 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFR_14425 74b9e29b156dcc12111f74fd46796395 271 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 159 2.5E-26 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFR_14425 74b9e29b156dcc12111f74fd46796395 271 SMART SM01092 166 267 0.0013 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_14425 74b9e29b156dcc12111f74fd46796395 271 SUPERFAMILY SSF55447 168 270 6.8E-13 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily AFR_09385 919bec6e6f80b235f53994ac538e97f0 381 SUPERFAMILY SSF53383 11 373 3.34E-72 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_09385 919bec6e6f80b235f53994ac538e97f0 381 Pfam PF00266 Aminotransferase class-V 13 364 6.4E-40 T 12-10-2018 IPR000192 Aminotransferase class V domain AFR_09385 919bec6e6f80b235f53994ac538e97f0 381 Gene3D G3DSA:3.40.640.10 23 257 6.7E-86 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_09385 919bec6e6f80b235f53994ac538e97f0 381 Gene3D G3DSA:3.90.1150.10 13 366 6.7E-86 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_09385 919bec6e6f80b235f53994ac538e97f0 381 PIRSF PIRSF005572 10 379 4.7E-99 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFR_18260 d0c605e5edc11b763c73c6a6c6cba5de 251 Gene3D G3DSA:3.40.50.720 2 249 1.4E-53 T 12-10-2018 AFR_18260 d0c605e5edc11b763c73c6a6c6cba5de 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 6.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18260 d0c605e5edc11b763c73c6a6c6cba5de 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 204 6.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18260 d0c605e5edc11b763c73c6a6c6cba5de 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18260 d0c605e5edc11b763c73c6a6c6cba5de 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 6.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18260 d0c605e5edc11b763c73c6a6c6cba5de 251 Pfam PF00106 short chain dehydrogenase 3 110 1.7E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18260 d0c605e5edc11b763c73c6a6c6cba5de 251 SUPERFAMILY SSF51735 3 219 1.1E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23890 3e71618ff1dacdb48b9bea2b8c286201 197 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 98 1.1E-9 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_23890 3e71618ff1dacdb48b9bea2b8c286201 197 Gene3D G3DSA:2.30.110.10 2 133 4.4E-18 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_23890 3e71618ff1dacdb48b9bea2b8c286201 197 SUPERFAMILY SSF50475 10 139 2.62E-12 T 12-10-2018 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 Gene3D G3DSA:1.20.140.10 236 389 3.3E-39 T 12-10-2018 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 128 5.0E-27 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 Gene3D G3DSA:1.10.540.10 1 129 5.3E-36 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 222 1.7E-24 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 Gene3D G3DSA:2.40.110.10 131 233 9.8E-37 T 12-10-2018 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 380 3.3E-32 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 SUPERFAMILY SSF56645 6 232 1.05E-73 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_02230 e1570beb0ce0e2937aa1e1d0eb42a01f 389 SUPERFAMILY SSF47203 234 384 1.77E-38 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_01875 675da92409d5c19c0175713b642e85f1 791 Gene3D G3DSA:3.40.50.300 61 260 1.2E-37 T 12-10-2018 AFR_01875 675da92409d5c19c0175713b642e85f1 791 Pfam PF00270 DEAD/DEAH box helicase 77 242 3.9E-23 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_01875 675da92409d5c19c0175713b642e85f1 791 Pfam PF09369 Domain of unknown function (DUF1998) 676 755 1.6E-20 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative AFR_01875 675da92409d5c19c0175713b642e85f1 791 SUPERFAMILY SSF52540 87 426 2.59E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01875 675da92409d5c19c0175713b642e85f1 791 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 39 782 0.0 T 12-10-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria AFR_01875 675da92409d5c19c0175713b642e85f1 791 Gene3D G3DSA:3.40.50.300 286 439 4.2E-19 T 12-10-2018 AFR_01875 675da92409d5c19c0175713b642e85f1 791 SMART SM00487 71 273 4.9E-31 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_01875 675da92409d5c19c0175713b642e85f1 791 SMART SM00490 335 416 2.2E-15 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_01875 675da92409d5c19c0175713b642e85f1 791 Pfam PF00271 Helicase conserved C-terminal domain 305 416 2.0E-11 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 SUPERFAMILY SSF46894 129 223 5.1E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 SMART SM00448 5 116 1.1E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 223 1.3E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 SUPERFAMILY SSF52172 7 122 1.57E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 Pfam PF00072 Response regulator receiver domain 7 117 1.1E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 Gene3D G3DSA:3.40.50.2300 2 125 8.3E-33 T 12-10-2018 AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 SMART SM00862 151 224 2.0E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_32070 4d311bdb510ee4e399b0c2157b82a3eb 226 Gene3D G3DSA:1.10.10.10 130 226 4.7E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42640 066ce74242ecac4e54a8a622dbac3fc1 266 Gene3D G3DSA:3.40.140.10 116 266 8.0E-52 T 12-10-2018 AFR_42640 066ce74242ecac4e54a8a622dbac3fc1 266 PIRSF PIRSF015626 2 266 3.5E-83 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFR_42640 066ce74242ecac4e54a8a622dbac3fc1 266 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 16 264 5.4E-48 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFR_42640 066ce74242ecac4e54a8a622dbac3fc1 266 SUPERFAMILY SSF53927 12 264 4.51E-77 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFR_42640 066ce74242ecac4e54a8a622dbac3fc1 266 Gene3D G3DSA:3.10.20.10 22 112 6.6E-7 T 12-10-2018 AFR_42640 066ce74242ecac4e54a8a622dbac3fc1 266 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 1 265 33.056 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFR_42640 066ce74242ecac4e54a8a622dbac3fc1 266 Pfam PF02634 FdhD/NarQ family 20 264 1.4E-82 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 Gene3D G3DSA:1.10.10.10 124 224 1.9E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 SMART SM00862 144 220 1.5E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 Pfam PF00072 Response regulator receiver domain 1 110 5.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 SMART SM00448 1 109 8.0E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 Gene3D G3DSA:3.40.50.2300 1 123 3.3E-37 T 12-10-2018 AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 SUPERFAMILY SSF46894 120 221 3.4E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 220 3.5E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_29420 b772fc5930a9befa5301ccc88589f9cb 225 SUPERFAMILY SSF52172 1 126 1.99E-41 T 12-10-2018 IPR011006 CheY-like superfamily AFR_37445 90ef6e7532a50020f9ef2d777f2fd4aa 387 Pfam PF02898 Nitric oxide synthase, oxygenase domain 24 375 5.7E-151 T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 AFR_37445 90ef6e7532a50020f9ef2d777f2fd4aa 387 Gene3D G3DSA:3.90.440.10 96 207 3.8E-147 T 12-10-2018 AFR_37445 90ef6e7532a50020f9ef2d777f2fd4aa 387 PIRSF PIRSF037219 17 382 3.6E-160 T 12-10-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 AFR_37445 90ef6e7532a50020f9ef2d777f2fd4aa 387 Gene3D G3DSA:3.90.340.10 24 369 3.8E-147 T 12-10-2018 AFR_37445 90ef6e7532a50020f9ef2d777f2fd4aa 387 SUPERFAMILY SSF56512 24 375 3.14E-157 T 12-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 AFR_37445 90ef6e7532a50020f9ef2d777f2fd4aa 387 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 79 86 - T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 AFR_37445 90ef6e7532a50020f9ef2d777f2fd4aa 387 Gene3D G3DSA:3.90.1230.10 208 314 3.8E-147 T 12-10-2018 AFR_12200 1a1d582a74a39b76829289874f4a3aba 357 Pfam PF03575 Peptidase family S51 3 211 9.1E-14 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 AFR_12200 1a1d582a74a39b76829289874f4a3aba 357 SUPERFAMILY SSF52317 71 212 3.2E-9 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_12200 1a1d582a74a39b76829289874f4a3aba 357 Pfam PF04266 ASCH domain 246 354 3.8E-7 T 12-10-2018 IPR007374 ASCH domain AFR_12200 1a1d582a74a39b76829289874f4a3aba 357 Gene3D G3DSA:3.40.50.880 1 227 2.7E-28 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_12200 1a1d582a74a39b76829289874f4a3aba 357 SUPERFAMILY SSF88697 241 354 6.21E-19 T 12-10-2018 IPR015947 PUA-like superfamily AFR_12200 1a1d582a74a39b76829289874f4a3aba 357 SMART SM01022 232 355 2.3E-8 T 12-10-2018 IPR007374 ASCH domain AFR_12200 1a1d582a74a39b76829289874f4a3aba 357 Gene3D G3DSA:3.10.400.10 231 357 4.3E-26 T 12-10-2018 AFR_25030 e088c99d8fc30af447985d0526e04a79 350 Gene3D G3DSA:3.20.20.80 78 343 1.8E-68 T 12-10-2018 AFR_25030 e088c99d8fc30af447985d0526e04a79 350 SUPERFAMILY SSF51445 99 340 1.91E-48 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_25030 e088c99d8fc30af447985d0526e04a79 350 Pfam PF02156 Glycosyl hydrolase family 26 153 287 1.7E-18 T 12-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 AFR_33980 1197824f461ebfc21044e67e3574d89d 384 Gene3D G3DSA:3.90.480.10 10 278 5.4E-31 T 12-10-2018 AFR_33980 1197824f461ebfc21044e67e3574d89d 384 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 10 66 4.0E-11 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_33980 1197824f461ebfc21044e67e3574d89d 384 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 228 286 1.9E-6 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_33980 1197824f461ebfc21044e67e3574d89d 384 SUPERFAMILY SSF55124 6 72 9.49E-14 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_33980 1197824f461ebfc21044e67e3574d89d 384 SUPERFAMILY SSF55124 157 290 2.99E-15 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_33980 1197824f461ebfc21044e67e3574d89d 384 SUPERFAMILY SSF56014 294 358 3.71E-5 T 12-10-2018 AFR_33980 1197824f461ebfc21044e67e3574d89d 384 Gene3D G3DSA:3.30.413.10 75 217 5.4E-31 T 12-10-2018 AFR_13295 31c6d87beefebda7c37e71c8bd598d22 728 Pfam PF13777 Domain of unknown function (DUF4173) 473 662 2.1E-59 T 12-10-2018 IPR025231 Domain of unknown function DUF4173 AFR_21360 a5bc9e8414fa778c1c8937bcab5517be 456 SUPERFAMILY SSF103473 17 442 2.22E-36 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_21360 a5bc9e8414fa778c1c8937bcab5517be 456 Gene3D G3DSA:1.20.1250.20 22 441 2.2E-27 T 12-10-2018 AFR_21360 a5bc9e8414fa778c1c8937bcab5517be 456 Pfam PF11700 Vacuole effluxer Atg22 like 10 448 3.8E-105 T 12-10-2018 IPR024671 Autophagy-related protein 22-like AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 Pfam PF00005 ABC transporter 21 162 1.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 Gene3D G3DSA:2.40.50.140 293 332 2.5E-16 T 12-10-2018 AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 Gene3D G3DSA:2.40.50.940 223 292 2.5E-16 T 12-10-2018 AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 SMART SM00382 29 212 5.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 Gene3D G3DSA:3.40.50.300 4 222 6.5E-61 T 12-10-2018 AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 SUPERFAMILY SSF52540 4 243 4.5E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_02255 28d3ebc7721615b560b0ea4cd06199d2 432 SUPERFAMILY SSF50331 238 332 1.31E-10 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_35510 8876b3149ebfa4bd59614d8e8de04ced 176 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 75.056 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFR_35510 8876b3149ebfa4bd59614d8e8de04ced 176 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 2 144 2.5E-47 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFR_35510 8876b3149ebfa4bd59614d8e8de04ced 176 Pfam PF03477 ATP cone domain 47 131 7.3E-14 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFR_05240 d94284218d0d75c13e19c6812fab7b9f 594 SUPERFAMILY SSF52540 8 377 5.41E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05240 d94284218d0d75c13e19c6812fab7b9f 594 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 32 351 7.7E-19 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_05240 d94284218d0d75c13e19c6812fab7b9f 594 Gene3D G3DSA:3.40.50.300 165 371 2.5E-10 T 12-10-2018 AFR_05980 a4e894d5623dd06cd20cdabffc7b4431 159 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 37 2.0E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_05980 a4e894d5623dd06cd20cdabffc7b4431 159 SUPERFAMILY SSF54523 17 107 3.61E-19 T 12-10-2018 AFR_05980 a4e894d5623dd06cd20cdabffc7b4431 159 PRINTS PR00813 Bacterial general secretion pathway protein G signature 52 70 8.2E-13 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AFR_05980 a4e894d5623dd06cd20cdabffc7b4431 159 PRINTS PR00813 Bacterial general secretion pathway protein G signature 16 41 8.2E-13 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AFR_05980 a4e894d5623dd06cd20cdabffc7b4431 159 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 15 35 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_05980 a4e894d5623dd06cd20cdabffc7b4431 159 Gene3D G3DSA:3.30.700.10 17 158 2.7E-23 T 12-10-2018 AFR_05980 a4e894d5623dd06cd20cdabffc7b4431 159 Pfam PF07963 Prokaryotic N-terminal methylation motif 12 36 6.4E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 21 132 3.2E-23 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 SUPERFAMILY SSF56003 153 736 1.44E-157 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 Gene3D G3DSA:3.30.365.10 162 382 9.5E-59 T 12-10-2018 AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 SUPERFAMILY SSF54665 5 134 8.64E-35 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 680 2.4E-122 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 Gene3D G3DSA:3.90.1170.50 1 133 9.6E-34 T 12-10-2018 AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 Gene3D G3DSA:3.30.365.20 404 738 1.4E-89 T 12-10-2018 AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 SMART SM01008 21 134 6.0E-37 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_19035 a4e3c7ae702206ea7683f26b82a3843b 738 Gene3D G3DSA:3.30.365.10 186 278 9.5E-59 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 3.2E-30 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 3.2E-30 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 3.2E-30 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 3.2E-30 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 3.2E-30 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 Pfam PF00117 Glutamine amidotransferase class-I 176 356 1.0E-37 T 12-10-2018 IPR017926 Glutamine amidotransferase AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 SUPERFAMILY SSF52021 1 141 3.27E-53 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 333 346 3.1E-11 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 3.1E-11 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 3.1E-11 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 SUPERFAMILY SSF52317 142 360 4.43E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 Gene3D G3DSA:3.50.30.20 1 142 2.5E-53 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 1 359 4.0E-132 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00097 Anthranilate synthase component II signature 214 223 3.4E-7 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00097 Anthranilate synthase component II signature 333 346 3.4E-7 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 PRINTS PR00097 Anthranilate synthase component II signature 242 253 3.4E-7 T 12-10-2018 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 SMART SM01097 1 126 3.2E-79 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 1 124 1.6E-48 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 Gene3D G3DSA:3.40.50.880 143 362 2.6E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_30620 21cfd9dce7c43748227ea5f3f907808b 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 362 43.31 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_36255 9136b5ece3d6b9c9f7377b0d4cf48765 134 SMART SM00345 14 73 2.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_36255 9136b5ece3d6b9c9f7377b0d4cf48765 134 SUPERFAMILY SSF46785 1 83 2.6E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_36255 9136b5ece3d6b9c9f7377b0d4cf48765 134 Gene3D G3DSA:1.10.10.10 8 107 6.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36255 9136b5ece3d6b9c9f7377b0d4cf48765 134 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.9E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_36255 9136b5ece3d6b9c9f7377b0d4cf48765 134 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.9E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_36255 9136b5ece3d6b9c9f7377b0d4cf48765 134 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 1.7E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 PIRSF PIRSF000654 15 272 7.2E-19 T 12-10-2018 AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 Gene3D G3DSA:3.30.200.20 1 89 1.0E-30 T 12-10-2018 AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 35 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 Pfam PF00069 Protein kinase domain 6 256 1.9E-49 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 SUPERFAMILY SSF56112 3 263 2.7E-69 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 128 140 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 SMART SM00220 6 261 7.2E-56 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_37605 9eb7f1674eaddddfeade56013f57daab 484 Gene3D G3DSA:1.10.510.10 91 286 1.8E-46 T 12-10-2018 AFR_31685 7161411764628c5f92bc8e8ba5fe394c 327 SUPERFAMILY SSF82171 46 310 2.55E-18 T 12-10-2018 AFR_31685 7161411764628c5f92bc8e8ba5fe394c 327 Gene3D G3DSA:2.120.10.30 150 326 3.0E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_31685 7161411764628c5f92bc8e8ba5fe394c 327 Gene3D G3DSA:2.120.10.30 38 149 4.3E-16 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_31685 7161411764628c5f92bc8e8ba5fe394c 327 Pfam PF07676 WD40-like Beta Propeller Repeat 176 190 0.13 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_31685 7161411764628c5f92bc8e8ba5fe394c 327 Pfam PF07676 WD40-like Beta Propeller Repeat 103 129 0.0075 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 154 9.3E-49 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 Gene3D G3DSA:1.10.1740.10 1 80 5.3E-10 T 12-10-2018 AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 154 3.0E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 Pfam PF04542 Sigma-70 region 2 20 79 1.6E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 SUPERFAMILY SSF88946 2 72 3.1E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 Pfam PF08281 Sigma-70, region 4 100 153 4.6E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 SUPERFAMILY SSF88659 96 155 4.3E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_25300 8947c9123aa1d8f5fc38a3afd531f21e 164 Gene3D G3DSA:1.10.10.10 81 158 2.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12780 ee90c9c4cb6271ca91eeca46ce23a231 177 Gene3D G3DSA:1.10.1740.10 1 88 1.5E-18 T 12-10-2018 AFR_12780 ee90c9c4cb6271ca91eeca46ce23a231 177 SUPERFAMILY SSF88946 1 111 6.28E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_12780 ee90c9c4cb6271ca91eeca46ce23a231 177 Gene3D G3DSA:1.10.10.10 113 177 4.6E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12780 ee90c9c4cb6271ca91eeca46ce23a231 177 Pfam PF04542 Sigma-70 region 2 15 93 2.0E-4 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_12780 ee90c9c4cb6271ca91eeca46ce23a231 177 Pfam PF08281 Sigma-70, region 4 121 170 5.7E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_12780 ee90c9c4cb6271ca91eeca46ce23a231 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 176 1.1E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_12780 ee90c9c4cb6271ca91eeca46ce23a231 177 SUPERFAMILY SSF88659 117 176 1.18E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_09735 d910977d67760d8027f2cb78c87f02d0 147 Gene3D G3DSA:3.30.40.60 56 147 3.0E-20 T 12-10-2018 AFR_09735 d910977d67760d8027f2cb78c87f02d0 147 SMART SM00507 69 118 1.9E-10 T 12-10-2018 IPR003615 HNH nuclease AFR_09735 d910977d67760d8027f2cb78c87f02d0 147 Pfam PF14279 HNH endonuclease 82 131 2.5E-14 T 12-10-2018 IPR029471 HNH endonuclease 5 AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 Pfam PF01726 LexA DNA binding domain 59 121 1.3E-26 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 Gene3D G3DSA:2.10.109.10 150 265 3.8E-39 T 12-10-2018 AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 Gene3D G3DSA:1.10.10.10 58 124 2.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 TIGRFAM TIGR00498 lexA: repressor LexA 59 265 6.5E-74 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 SUPERFAMILY SSF51306 145 263 1.53E-34 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 Pfam PF00717 Peptidase S24-like 184 248 5.3E-14 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 SUPERFAMILY SSF46785 59 124 2.27E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 192 203 3.8E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 181 191 3.8E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 220 232 3.8E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFR_35520 cdcda94049dc5779cd280a8007d11bdf 265 Hamap MF_00015 LexA repressor [lexA]. 59 265 33.731 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFR_27895 51ef58e65623383dd3430148a4f77eba 369 Gene3D G3DSA:3.30.1540.10 226 308 1.5E-29 T 12-10-2018 AFR_27895 51ef58e65623383dd3430148a4f77eba 369 Pfam PF02515 CoA-transferase family III 8 357 4.8E-80 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 AFR_27895 51ef58e65623383dd3430148a4f77eba 369 SUPERFAMILY SSF89796 6 367 4.06E-111 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily AFR_27895 51ef58e65623383dd3430148a4f77eba 369 Gene3D G3DSA:3.40.50.10540 3 225 3.6E-76 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily AFR_27895 51ef58e65623383dd3430148a4f77eba 369 Gene3D G3DSA:3.30.60.110 309 341 1.6E-8 T 12-10-2018 AFR_06210 547e268a669e3a7e168675278c5c3677 312 Pfam PF12833 Helix-turn-helix domain 227 306 5.0E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_06210 547e268a669e3a7e168675278c5c3677 312 Pfam PF01965 DJ-1/PfpI family 62 166 3.7E-12 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_06210 547e268a669e3a7e168675278c5c3677 312 Gene3D G3DSA:1.10.10.60 205 309 2.8E-24 T 12-10-2018 AFR_06210 547e268a669e3a7e168675278c5c3677 312 SUPERFAMILY SSF46689 205 254 1.52E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06210 547e268a669e3a7e168675278c5c3677 312 SUPERFAMILY SSF46689 258 307 4.3E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06210 547e268a669e3a7e168675278c5c3677 312 SMART SM00342 221 304 2.1E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_06210 547e268a669e3a7e168675278c5c3677 312 SUPERFAMILY SSF52317 6 187 1.03E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_06210 547e268a669e3a7e168675278c5c3677 312 Gene3D G3DSA:3.40.50.880 1 195 3.2E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_15555 c37de549ee8b4e4d7184e5d3c38c2052 292 Gene3D G3DSA:3.40.109.10 4 90 1.8E-18 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_15555 c37de549ee8b4e4d7184e5d3c38c2052 292 Gene3D G3DSA:3.40.109.10 95 292 1.1E-20 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 85 102 - T 12-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 SUPERFAMILY SSF46785 152 226 4.41E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 SUPERFAMILY SSF51206 10 145 1.96E-31 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 Gene3D G3DSA:2.60.120.10 7 152 6.8E-35 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 SMART SM00419 169 217 3.4E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 Pfam PF13545 Crp-like helix-turn-helix domain 155 223 4.8E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 SMART SM00100 17 135 1.3E-23 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 Pfam PF00027 Cyclic nucleotide-binding domain 36 122 3.7E-19 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_09590 681053ca9a5ef26d01331bc893d0ab0a 230 Gene3D G3DSA:1.10.10.10 153 226 3.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10900 34eebd09ef885a9575b678a881bf3a3f 215 Gene3D G3DSA:1.10.150.520 15 84 1.7E-28 T 12-10-2018 AFR_10900 34eebd09ef885a9575b678a881bf3a3f 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 105 183 1.2E-11 T 12-10-2018 AFR_10900 34eebd09ef885a9575b678a881bf3a3f 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 178 6.5E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_10900 34eebd09ef885a9575b678a881bf3a3f 215 Gene3D G3DSA:3.40.50.1000 4 189 1.7E-28 T 12-10-2018 IPR023214 HAD superfamily AFR_10900 34eebd09ef885a9575b678a881bf3a3f 215 SUPERFAMILY SSF56784 5 204 3.48E-30 T 12-10-2018 IPR036412 HAD-like superfamily AFR_41670 74c182f8487d354e4e1812f5fd8dc579 799 Gene3D G3DSA:1.10.3810.10 65 275 2.0E-68 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_41670 74c182f8487d354e4e1812f5fd8dc579 799 SUPERFAMILY SSF53955 60 282 2.36E-63 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_41670 74c182f8487d354e4e1812f5fd8dc579 799 Pfam PF00905 Penicillin binding protein transpeptidase domain 368 647 4.1E-18 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_41670 74c182f8487d354e4e1812f5fd8dc579 799 SUPERFAMILY SSF56601 245 709 1.47E-64 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_41670 74c182f8487d354e4e1812f5fd8dc579 799 Pfam PF00912 Transglycosylase 75 259 1.4E-57 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_41670 74c182f8487d354e4e1812f5fd8dc579 799 Gene3D G3DSA:3.30.10.20 718 779 6.9E-11 T 12-10-2018 AFR_41670 74c182f8487d354e4e1812f5fd8dc579 799 Gene3D G3DSA:3.40.710.10 310 715 1.2E-62 T 12-10-2018 AFR_05845 7e9597175febb28581a89f95e9d2a1ed 226 Gene3D G3DSA:3.40.50.300 1 223 5.6E-68 T 12-10-2018 AFR_05845 7e9597175febb28581a89f95e9d2a1ed 226 SMART SM00382 28 215 2.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_05845 7e9597175febb28581a89f95e9d2a1ed 226 Pfam PF00005 ABC transporter 19 166 1.7E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_05845 7e9597175febb28581a89f95e9d2a1ed 226 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 5.9E-84 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 AFR_05845 7e9597175febb28581a89f95e9d2a1ed 226 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_05845 7e9597175febb28581a89f95e9d2a1ed 226 SUPERFAMILY SSF52540 1 220 4.79E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25110 2c6c83fa65a98f8df848fb25bd97663c 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 178 6.8E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_25110 2c6c83fa65a98f8df848fb25bd97663c 190 Gene3D G3DSA:1.10.1740.10 4 120 4.2E-19 T 12-10-2018 AFR_25110 2c6c83fa65a98f8df848fb25bd97663c 190 SUPERFAMILY SSF88946 8 111 5.97E-20 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_25110 2c6c83fa65a98f8df848fb25bd97663c 190 Pfam PF04542 Sigma-70 region 2 27 94 1.4E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.4E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 SUPERFAMILY SSF48498 84 174 4.45E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 SUPERFAMILY SSF46689 10 86 3.44E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 Pfam PF16859 Bacterial transcriptional repressor C-terminal 109 166 2.2E-9 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_39605 d5ec6e75ca80beadc7e5667da1059828 194 Gene3D G3DSA:1.10.357.10 10 183 1.5E-39 T 12-10-2018 AFR_24245 77dbe83c6ddcf7cd92b2417738d386b2 559 SUPERFAMILY SSF53850 34 548 7.6E-93 T 12-10-2018 AFR_24245 77dbe83c6ddcf7cd92b2417738d386b2 559 PIRSF PIRSF002741 1 557 1.6E-60 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFR_24245 77dbe83c6ddcf7cd92b2417738d386b2 559 Gene3D G3DSA:3.40.190.10 10 300 3.3E-52 T 12-10-2018 AFR_24245 77dbe83c6ddcf7cd92b2417738d386b2 559 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 472 9.2E-69 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFR_24245 77dbe83c6ddcf7cd92b2417738d386b2 559 Gene3D G3DSA:3.10.105.10 311 530 6.5E-57 T 12-10-2018 AFR_32735 f9911cf55bbdf699582b190b91187bf1 364 SUPERFAMILY SSF51679 10 356 4.45E-81 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_32735 f9911cf55bbdf699582b190b91187bf1 364 Gene3D G3DSA:3.20.20.30 8 361 1.4E-100 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_32735 f9911cf55bbdf699582b190b91187bf1 364 Pfam PF00296 Luciferase-like monooxygenase 5 325 6.3E-80 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 Gene3D G3DSA:1.10.357.10 78 218 1.9E-27 T 12-10-2018 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 7.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 Gene3D G3DSA:1.10.10.60 4 77 5.1E-21 T 12-10-2018 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 SUPERFAMILY SSF46689 12 85 2.9E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 PRINTS PR00400 Tetracycline repressor protein signature 147 166 8.5E-10 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 PRINTS PR00400 Tetracycline repressor protein signature 35 58 8.5E-10 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 PRINTS PR00400 Tetracycline repressor protein signature 201 215 8.5E-10 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 PRINTS PR00400 Tetracycline repressor protein signature 91 110 8.5E-10 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 SUPERFAMILY SSF48498 86 215 3.11E-20 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_29305 bd5d7ad6781d42c0be7d8898c55493bb 233 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 216 3.7E-15 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_00365 3ba1cb7a286f2f180f04380dfb848e0c 173 Gene3D G3DSA:3.90.79.10 23 168 2.4E-22 T 12-10-2018 AFR_00365 3ba1cb7a286f2f180f04380dfb848e0c 173 Pfam PF00293 NUDIX domain 44 147 6.2E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_00365 3ba1cb7a286f2f180f04380dfb848e0c 173 PRINTS PR00502 NUDIX hydrolase family signature 81 96 4.7E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_00365 3ba1cb7a286f2f180f04380dfb848e0c 173 PRINTS PR00502 NUDIX hydrolase family signature 67 81 4.7E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_00365 3ba1cb7a286f2f180f04380dfb848e0c 173 SUPERFAMILY SSF55811 43 164 2.71E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_00365 3ba1cb7a286f2f180f04380dfb848e0c 173 ProSitePatterns PS00893 Nudix box signature. 72 93 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_24960 eb1e7fb832042ec5abb1fb23553d9e3c 486 PIRSF PIRSF006060 4 467 3.5E-97 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_24960 eb1e7fb832042ec5abb1fb23553d9e3c 486 Gene3D G3DSA:1.20.1740.10 21 464 1.5E-125 T 12-10-2018 AFR_24960 eb1e7fb832042ec5abb1fb23553d9e3c 486 Pfam PF13520 Amino acid permease 28 427 2.6E-60 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 785 908 3.2E-30 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 Pfam PF13244 Domain of unknown function (DUF4040) 590 653 1.0E-22 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 Pfam PF00361 Proton-conducting membrane transporter 125 412 5.2E-60 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 60 111 9.7E-7 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 1.7E-29 T 12-10-2018 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 1.7E-29 T 12-10-2018 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 1.7E-29 T 12-10-2018 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 405 424 1.7E-29 T 12-10-2018 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 303 315 1.7E-29 T 12-10-2018 AFR_30130 10e3d859ee17d2e184ca371b9e3301ce 927 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 102 122 1.7E-29 T 12-10-2018 AFR_19680 10628cb96bcb6ff891dfe9cc2d5030ad 120 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 13 120 5.6E-9 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 AFR_19680 10628cb96bcb6ff891dfe9cc2d5030ad 120 Gene3D G3DSA:3.10.450.50 2 120 7.9E-19 T 12-10-2018 AFR_19680 10628cb96bcb6ff891dfe9cc2d5030ad 120 SUPERFAMILY SSF54427 12 120 2.2E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_19680 10628cb96bcb6ff891dfe9cc2d5030ad 120 Pfam PF13474 SnoaL-like domain 10 115 9.0E-12 T 12-10-2018 IPR037401 SnoaL-like domain AFR_31935 6a103fa45129b448198c7b0c11dcdbc5 561 Gene3D G3DSA:3.40.190.10 53 543 6.4E-139 T 12-10-2018 AFR_31935 6a103fa45129b448198c7b0c11dcdbc5 561 Gene3D G3DSA:3.90.76.10 75 180 6.4E-139 T 12-10-2018 AFR_31935 6a103fa45129b448198c7b0c11dcdbc5 561 PIRSF PIRSF002741 1 536 3.1E-66 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFR_31935 6a103fa45129b448198c7b0c11dcdbc5 561 SUPERFAMILY SSF53850 40 538 4.34E-94 T 12-10-2018 AFR_31935 6a103fa45129b448198c7b0c11dcdbc5 561 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 453 2.2E-64 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFR_31935 6a103fa45129b448198c7b0c11dcdbc5 561 Gene3D G3DSA:3.10.105.10 280 521 6.4E-139 T 12-10-2018 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 SUPERFAMILY SSF142984 227 302 4.18E-10 T 12-10-2018 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 Gene3D G3DSA:3.40.50.11540 50 215 2.7E-51 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 Gene3D G3DSA:3.10.20.600 216 305 3.8E-15 T 12-10-2018 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 SUPERFAMILY SSF142019 30 224 7.59E-44 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 46 202 5.3E-34 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 312 394 8.0E-16 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 Gene3D G3DSA:1.20.1440.230 309 400 2.9E-9 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 SUPERFAMILY SSF140490 306 399 1.83E-14 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_33480 2d766b7320a260ab047eeb79fa302f55 402 Pfam PF10531 SLBB domain 227 268 6.7E-6 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_02860 34dceba158f626e081858246750089c1 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 4.1E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_02860 34dceba158f626e081858246750089c1 253 SUPERFAMILY SSF46785 3 70 2.13E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_02860 34dceba158f626e081858246750089c1 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.0E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_02860 34dceba158f626e081858246750089c1 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.0E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_02860 34dceba158f626e081858246750089c1 253 Pfam PF00455 DeoR C terminal sensor domain 77 233 3.4E-44 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain AFR_02860 34dceba158f626e081858246750089c1 253 SMART SM00420 6 58 3.8E-13 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_02860 34dceba158f626e081858246750089c1 253 SMART SM01134 73 234 1.0E-54 T 12-10-2018 AFR_02860 34dceba158f626e081858246750089c1 253 Gene3D G3DSA:1.10.10.10 1 86 4.7E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02860 34dceba158f626e081858246750089c1 253 SUPERFAMILY SSF100950 76 234 1.05E-24 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_31945 fa31d5bb8ff3c5f9dcda4d7b6df42909 326 Gene3D G3DSA:1.10.3720.10 91 315 5.2E-16 T 12-10-2018 IPR035906 MetI-like superfamily AFR_31945 fa31d5bb8ff3c5f9dcda4d7b6df42909 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 324 1.0E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_31945 fa31d5bb8ff3c5f9dcda4d7b6df42909 326 SUPERFAMILY SSF161098 95 323 4.14E-14 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15560 63ea3ebbf71fb6c42aa40b6adf16da0e 351 Gene3D G3DSA:3.40.630.30 8 351 4.4E-12 T 12-10-2018 AFR_15560 63ea3ebbf71fb6c42aa40b6adf16da0e 351 SUPERFAMILY SSF55729 9 346 6.03E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_32290 63f01e371f17dbbd8dcdbe7a9b661080 336 Gene3D G3DSA:3.40.50.1980 38 181 1.4E-36 T 12-10-2018 AFR_32290 63f01e371f17dbbd8dcdbe7a9b661080 336 SUPERFAMILY SSF53807 52 329 8.24E-48 T 12-10-2018 AFR_32290 63f01e371f17dbbd8dcdbe7a9b661080 336 Gene3D G3DSA:3.40.50.1980 184 336 5.2E-37 T 12-10-2018 AFR_32290 63f01e371f17dbbd8dcdbe7a9b661080 336 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 6 29 1.0E-5 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFR_32290 63f01e371f17dbbd8dcdbe7a9b661080 336 Pfam PF01497 Periplasmic binding protein 69 303 6.5E-21 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 Gene3D G3DSA:3.40.50.720 1 183 5.5E-76 T 12-10-2018 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 1.8E-129 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 PIRSF PIRSF000116 204 334 1.2E-14 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 PIRSF PIRSF000116 1 211 2.6E-38 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 Gene3D G3DSA:1.10.3730.40 184 337 1.7E-70 T 12-10-2018 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 SUPERFAMILY SSF51735 4 184 1.29E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 5.6E-63 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 44.882 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 SUPERFAMILY SSF48179 185 330 8.16E-67 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_36885 bb82cd507aa0eb0234310716f116b0d6 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 1.2E-74 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFR_31625 658288d844f760e4361abeaa1d8cedda 239 Gene3D G3DSA:3.90.550.10 1 210 4.9E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_31625 658288d844f760e4361abeaa1d8cedda 239 Pfam PF00535 Glycosyl transferase family 2 1 126 8.9E-18 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_31625 658288d844f760e4361abeaa1d8cedda 239 SUPERFAMILY SSF53448 1 230 4.13E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_10905 edda7cff7d857f5cf939937d042013e9 294 Gene3D G3DSA:1.10.510.10 190 291 1.2E-20 T 12-10-2018 AFR_10905 edda7cff7d857f5cf939937d042013e9 294 SMART SM00090 34 289 9.8E-9 T 12-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AFR_10905 edda7cff7d857f5cf939937d042013e9 294 SUPERFAMILY SSF56112 66 270 2.59E-13 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_10905 edda7cff7d857f5cf939937d042013e9 294 Pfam PF01163 RIO1 family 116 280 2.7E-29 T 12-10-2018 AFR_10085 65845f0d09da7523c1fc3fb5e858b5e3 553 Pfam PF13614 AAA domain 302 473 7.2E-7 T 12-10-2018 IPR025669 AAA domain AFR_10085 65845f0d09da7523c1fc3fb5e858b5e3 553 SUPERFAMILY SSF52540 300 541 2.12E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10085 65845f0d09da7523c1fc3fb5e858b5e3 553 Gene3D G3DSA:3.40.50.300 299 542 2.4E-21 T 12-10-2018 AFR_38275 327a5e26812e2a86a6c83b634cab1006 252 Gene3D G3DSA:2.160.20.100 151 252 3.9E-21 T 12-10-2018 AFR_38275 327a5e26812e2a86a6c83b634cab1006 252 SUPERFAMILY SSF141571 56 245 2.88E-21 T 12-10-2018 AFR_38275 327a5e26812e2a86a6c83b634cab1006 252 Pfam PF00805 Pentapeptide repeats (8 copies) 193 232 2.6E-14 T 12-10-2018 IPR001646 Pentapeptide repeat AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 SUPERFAMILY SSF46785 200 251 3.34E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 SMART SM00344 203 304 0.0011 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 Pfam PF01037 Lrp/AsnC ligand binding domain 268 330 4.6E-6 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 Gene3D G3DSA:3.30.70.920 253 342 2.7E-8 T 12-10-2018 AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 SUPERFAMILY SSF46785 11 60 1.55E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 Gene3D G3DSA:1.10.10.10 8 61 3.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 1.5E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 1.5E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 1.5E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 SUPERFAMILY SSF54909 260 333 7.91E-7 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 Pfam PF13404 AsnC-type helix-turn-helix domain 12 53 3.8E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 Pfam PF13404 AsnC-type helix-turn-helix domain 203 239 2.3E-8 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_30825 09850b16c3cb818c1170e3f2341a22f7 353 Gene3D G3DSA:1.10.10.10 201 248 1.1E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40445 18005aa5bfdb59201ca647cd5538b246 224 Pfam PF02108 Flagellar assembly protein FliH 85 213 1.5E-11 T 12-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 SUPERFAMILY SSF46785 6 112 2.04E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 9.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 9.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 9.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 Gene3D G3DSA:1.10.10.10 4 89 1.3E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 SUPERFAMILY SSF53850 93 293 1.45E-30 T 12-10-2018 AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 Pfam PF03466 LysR substrate binding domain 92 287 4.6E-30 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 64 2.3E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 Gene3D G3DSA:3.40.190.10 94 274 1.9E-34 T 12-10-2018 AFR_29265 b216367a61fd4dc7ff714c9b29463969 298 Gene3D G3DSA:3.40.190.10 171 270 1.9E-34 T 12-10-2018 AFR_39850 2efef069186dc7770f751f2bd3d8a27f 813 Pfam PF13641 Glycosyltransferase like family 2 372 591 2.2E-43 T 12-10-2018 AFR_39850 2efef069186dc7770f751f2bd3d8a27f 813 Gene3D G3DSA:3.90.550.10 367 582 3.2E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_39850 2efef069186dc7770f751f2bd3d8a27f 813 SUPERFAMILY SSF88713 84 281 1.16E-50 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_39850 2efef069186dc7770f751f2bd3d8a27f 813 Pfam PF01522 Polysaccharide deacetylase 83 193 6.8E-27 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_39850 2efef069186dc7770f751f2bd3d8a27f 813 Gene3D G3DSA:3.20.20.370 74 290 4.6E-59 T 12-10-2018 AFR_39850 2efef069186dc7770f751f2bd3d8a27f 813 SUPERFAMILY SSF53448 369 604 2.19E-62 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_03755 620c093bb3da661e3e527762fbf126a1 323 SUPERFAMILY SSF46785 2 56 2.93E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_03755 620c093bb3da661e3e527762fbf126a1 323 Pfam PF13280 WYL domain 147 317 1.1E-27 T 12-10-2018 IPR026881 WYL domain AFR_03755 620c093bb3da661e3e527762fbf126a1 323 Gene3D G3DSA:1.10.10.10 1 62 1.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03755 620c093bb3da661e3e527762fbf126a1 323 Pfam PF08279 HTH domain 10 57 8.5E-15 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_03755 620c093bb3da661e3e527762fbf126a1 323 PIRSF PIRSF016838 69 323 6.0E-13 T 12-10-2018 IPR028349 Protein PafC AFR_03755 620c093bb3da661e3e527762fbf126a1 323 PIRSF PIRSF016838 1 53 4.5E-4 T 12-10-2018 IPR028349 Protein PafC AFR_29395 12e5d074ce178685a073536b124fd12b 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_29395 12e5d074ce178685a073536b124fd12b 253 SUPERFAMILY SSF51735 2 250 4.96E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 3.1E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 247 4.0E-48 T 12-10-2018 AFR_29395 12e5d074ce178685a073536b124fd12b 253 Gene3D G3DSA:3.40.50.720 2 252 2.6E-60 T 12-10-2018 AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29395 12e5d074ce178685a073536b124fd12b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03800 7756da344d2f78854658733e52c12883 291 SUPERFAMILY SSF56349 5 261 5.0E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_03800 7756da344d2f78854658733e52c12883 291 Gene3D G3DSA:1.10.150.130 1 78 8.9E-14 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_03800 7756da344d2f78854658733e52c12883 291 Gene3D G3DSA:1.10.443.10 79 271 9.2E-33 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_03800 7756da344d2f78854658733e52c12883 291 Pfam PF00589 Phage integrase family 80 255 1.0E-21 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_40620 63c6fe72e2fb697d9701dd585b9a446a 253 SUPERFAMILY SSF109854 6 141 7.88E-7 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_40620 63c6fe72e2fb697d9701dd585b9a446a 253 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 232 3.7E-26 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_40620 63c6fe72e2fb697d9701dd585b9a446a 253 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 136 3.7E-16 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_40620 63c6fe72e2fb697d9701dd585b9a446a 253 Pfam PF07398 MDMPI C-terminal domain 150 247 1.1E-11 T 12-10-2018 IPR010872 MDMPI C-terminal AFR_06865 21b30f8d7d74f1467883ee46a9558b15 168 Pfam PF04229 GrpB protein 1 151 1.6E-38 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase AFR_06865 21b30f8d7d74f1467883ee46a9558b15 168 Gene3D G3DSA:3.30.460.10 1 158 1.9E-37 T 12-10-2018 AFR_06865 21b30f8d7d74f1467883ee46a9558b15 168 SUPERFAMILY SSF81301 3 155 1.21E-33 T 12-10-2018 AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 SUPERFAMILY SSF53448 8 256 4.98E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 Gene3D G3DSA:2.160.10.10 259 444 1.1E-46 T 12-10-2018 AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 324 354 6.2E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 400 434 2.7E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 460 2.8E-160 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 458 38.233 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 409 437 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 Gene3D G3DSA:3.90.550.10 1 258 1.0E-68 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 Pfam PF12804 MobA-like NTP transferase domain 9 150 5.1E-21 T 12-10-2018 IPR025877 MobA-like NTP transferase AFR_39725 8804c3df6dcf22307758a8646a4a63bb 482 SUPERFAMILY SSF51161 222 440 4.32E-38 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_08495 c39f7935b5f6503effefddd8a537995e 689 Pfam PF07238 PilZ domain 578 678 8.7E-13 T 12-10-2018 IPR009875 PilZ domain GO:0035438 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 Gene3D G3DSA:1.10.287.950 343 578 1.1E-31 T 12-10-2018 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 SUPERFAMILY SSF58104 321 579 6.67E-38 T 12-10-2018 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 437 556 3.8E-22 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 Gene3D G3DSA:2.40.10.220 579 687 4.1E-9 T 12-10-2018 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 406 1.1E-14 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 457 484 1.1E-14 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 486 515 1.1E-14 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 Pfam PF00672 HAMP domain 312 348 3.2E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 SUPERFAMILY SSF141371 577 684 3.53E-10 T 12-10-2018 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 SMART SM00283 358 592 3.3E-5 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 SMART SM00304 213 264 47.0 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_08495 c39f7935b5f6503effefddd8a537995e 689 SMART SM00304 301 353 2.0E-5 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 SMART SM00458 441 565 1.3E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 Gene3D G3DSA:3.40.50.880 22 252 2.1E-84 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 Pfam PF06283 Trehalose utilisation 36 246 4.8E-76 T 12-10-2018 IPR029010 ThuA-like domain AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 SUPERFAMILY SSF50370 447 564 7.99E-38 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 Gene3D G3DSA:2.80.10.50 436 565 2.8E-41 T 12-10-2018 AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 SUPERFAMILY SSF52317 33 258 6.41E-44 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 Pfam PF06439 Domain of Unknown Function (DUF1080) 259 434 2.1E-37 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 Gene3D G3DSA:2.60.120.560 253 435 3.5E-41 T 12-10-2018 AFR_29205 fd81c3d1bd6f0be1f00d28ed6090a88b 565 Pfam PF00652 Ricin-type beta-trefoil lectin domain 444 562 6.9E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17185 83527f3a66429ed68835fd581e3a958f 772 Gene3D G3DSA:3.20.20.450 508 766 3.9E-90 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17185 83527f3a66429ed68835fd581e3a958f 772 Pfam PF00990 Diguanylate cyclase, GGDEF domain 339 490 3.1E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_17185 83527f3a66429ed68835fd581e3a958f 772 Gene3D G3DSA:3.30.70.270 337 507 3.2E-52 T 12-10-2018 AFR_17185 83527f3a66429ed68835fd581e3a958f 772 SUPERFAMILY SSF141868 510 754 9.94E-80 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17185 83527f3a66429ed68835fd581e3a958f 772 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 335 491 1.8E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_17185 83527f3a66429ed68835fd581e3a958f 772 SMART SM00052 504 751 8.8E-103 T 12-10-2018 IPR001633 EAL domain AFR_17185 83527f3a66429ed68835fd581e3a958f 772 SUPERFAMILY SSF55073 344 495 5.02E-44 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_17185 83527f3a66429ed68835fd581e3a958f 772 Pfam PF00563 EAL domain 510 746 6.4E-70 T 12-10-2018 IPR001633 EAL domain AFR_17185 83527f3a66429ed68835fd581e3a958f 772 SMART SM00267 328 494 4.5E-57 T 12-10-2018 IPR000160 GGDEF domain AFR_24055 17c6f6234e756cc5381bfb339e45c14d 242 Pfam PF00005 ABC transporter 1 126 4.8E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_24055 17c6f6234e756cc5381bfb339e45c14d 242 SUPERFAMILY SSF52540 1 187 3.88E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24055 17c6f6234e756cc5381bfb339e45c14d 242 SMART SM00382 1 174 1.1E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_24055 17c6f6234e756cc5381bfb339e45c14d 242 Gene3D G3DSA:3.40.50.300 1 220 3.8E-44 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 Gene3D G3DSA:3.50.50.60 3 360 1.5E-102 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 SUPERFAMILY SSF51905 2 368 1.12E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 331 1.9E-48 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 351 1.9E-48 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.9E-48 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 1.9E-48 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 315 1.9E-48 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 351 367 1.9E-48 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 Gene3D G3DSA:3.40.30.120 412 567 2.0E-50 T 12-10-2018 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 Pfam PF01494 FAD binding domain 2 366 3.8E-121 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_25335 1c76ca7d35d022084122f744fd0fa228 568 Gene3D G3DSA:3.30.9.50 69 297 1.5E-102 T 12-10-2018 AFR_18620 9581307253bea4dc14956220b94b589b 508 Gene3D G3DSA:3.30.70.270 329 495 2.2E-44 T 12-10-2018 AFR_18620 9581307253bea4dc14956220b94b589b 508 Gene3D G3DSA:1.25.40.10 140 318 1.6E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18620 9581307253bea4dc14956220b94b589b 508 SUPERFAMILY SSF48452 162 299 1.23E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18620 9581307253bea4dc14956220b94b589b 508 SMART SM00267 333 496 2.5E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_18620 9581307253bea4dc14956220b94b589b 508 SUPERFAMILY SSF55073 349 493 1.96E-34 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_18620 9581307253bea4dc14956220b94b589b 508 Pfam PF00990 Diguanylate cyclase, GGDEF domain 344 492 1.7E-30 T 12-10-2018 IPR000160 GGDEF domain AFR_18620 9581307253bea4dc14956220b94b589b 508 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 343 494 4.7E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 SUPERFAMILY SSF46689 55 106 2.96E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 Gene3D G3DSA:1.10.10.60 56 115 2.8E-10 T 12-10-2018 AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 Pfam PF06445 GyrI-like small molecule binding domain 126 283 6.7E-21 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 Pfam PF12833 Helix-turn-helix domain 25 103 4.8E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 Gene3D G3DSA:3.20.80.10 126 286 5.3E-29 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 SUPERFAMILY SSF55136 126 284 2.2E-20 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 SMART SM00871 126 284 9.6E-23 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 SUPERFAMILY SSF46689 3 53 1.52E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 Gene3D G3DSA:1.10.10.60 2 55 1.9E-11 T 12-10-2018 AFR_15600 b067a369f73d03c966a6fd08d86ee8d5 288 SMART SM00342 19 102 6.4E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 Pfam PF06827 Zinc finger found in FPG and IleRS 249 278 4.7E-9 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 SMART SM01232 136 228 1.6E-38 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 119 1.7E-34 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 SUPERFAMILY SSF46946 136 225 1.47E-25 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 SUPERFAMILY SSF81624 2 145 1.11E-35 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 SMART SM00898 2 121 5.1E-49 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 SUPERFAMILY SSF57716 228 277 6.84E-16 T 12-10-2018 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 276 3.6E-89 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 277 40.721 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 Gene3D G3DSA:3.20.190.10 2 132 1.1E-38 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 136 223 4.4E-23 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_36515 732d4bd0e0c2d6e6707f25386a743cf3 284 Gene3D G3DSA:1.10.8.50 138 278 2.1E-44 T 12-10-2018 AFR_23650 d37d75f88374605caece4afff2670591 312 Gene3D G3DSA:3.40.190.10 173 275 2.5E-42 T 12-10-2018 AFR_23650 d37d75f88374605caece4afff2670591 312 Gene3D G3DSA:3.40.190.10 95 282 2.5E-42 T 12-10-2018 AFR_23650 d37d75f88374605caece4afff2670591 312 SUPERFAMILY SSF46785 8 115 5.37E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23650 d37d75f88374605caece4afff2670591 312 Gene3D G3DSA:1.10.10.10 6 89 6.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23650 d37d75f88374605caece4afff2670591 312 SUPERFAMILY SSF53850 94 304 5.02E-36 T 12-10-2018 AFR_23650 d37d75f88374605caece4afff2670591 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 2.2E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23650 d37d75f88374605caece4afff2670591 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 7.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23650 d37d75f88374605caece4afff2670591 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 7.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23650 d37d75f88374605caece4afff2670591 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_23650 d37d75f88374605caece4afff2670591 312 Pfam PF03466 LysR substrate binding domain 91 299 3.5E-40 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_38865 968434a8a92643f11f1beba5069fe80f 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_38865 968434a8a92643f11f1beba5069fe80f 238 SMART SM00382 29 215 7.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_38865 968434a8a92643f11f1beba5069fe80f 238 Pfam PF00005 ABC transporter 20 165 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_38865 968434a8a92643f11f1beba5069fe80f 238 SUPERFAMILY SSF52540 4 235 3.13E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38865 968434a8a92643f11f1beba5069fe80f 238 Gene3D G3DSA:3.40.50.300 2 238 1.0E-63 T 12-10-2018 AFR_23450 861b07749c0936279857a074942bfa72 295 SUPERFAMILY SSF88946 10 95 2.04E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23450 861b07749c0936279857a074942bfa72 295 SUPERFAMILY SSF54427 176 291 3.65E-8 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_23450 861b07749c0936279857a074942bfa72 295 SUPERFAMILY SSF88659 113 165 2.43E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_23450 861b07749c0936279857a074942bfa72 295 Pfam PF08281 Sigma-70, region 4 114 164 3.0E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_23450 861b07749c0936279857a074942bfa72 295 Gene3D G3DSA:1.10.1740.10 6 76 1.3E-7 T 12-10-2018 AFR_23450 861b07749c0936279857a074942bfa72 295 Pfam PF04542 Sigma-70 region 2 16 79 5.0E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23450 861b07749c0936279857a074942bfa72 295 Gene3D G3DSA:1.10.10.10 116 167 3.2E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23450 861b07749c0936279857a074942bfa72 295 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 164 1.3E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_19810 d233eba5831f558e72d2af04ba2d3439 166 Gene3D G3DSA:3.40.630.30 1 145 1.6E-22 T 12-10-2018 AFR_19810 d233eba5831f558e72d2af04ba2d3439 166 Pfam PF13302 Acetyltransferase (GNAT) domain 2 135 1.2E-14 T 12-10-2018 IPR000182 GNAT domain AFR_19810 d233eba5831f558e72d2af04ba2d3439 166 SUPERFAMILY SSF55729 2 139 5.93E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_22790 248d0a7e8760a911e74f6d3de0b42bd1 268 SUPERFAMILY SSF56176 20 168 1.36E-30 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_22790 248d0a7e8760a911e74f6d3de0b42bd1 268 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 19 168 1.3E-20 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFR_22790 248d0a7e8760a911e74f6d3de0b42bd1 268 Gene3D G3DSA:3.30.465.10 49 168 1.3E-26 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_20915 740f196999a2bcf8cc5154104b081ba0 235 Pfam PF00005 ABC transporter 17 156 1.3E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20915 740f196999a2bcf8cc5154104b081ba0 235 SMART SM00382 26 204 1.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20915 740f196999a2bcf8cc5154104b081ba0 235 Gene3D G3DSA:3.40.50.300 1 233 6.8E-51 T 12-10-2018 AFR_20915 740f196999a2bcf8cc5154104b081ba0 235 SUPERFAMILY SSF52540 2 220 4.61E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 Gene3D G3DSA:3.40.50.720 4 235 2.0E-60 T 12-10-2018 AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PIRSF PIRSF000126 1 258 1.3E-72 T 12-10-2018 AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 Pfam PF00106 short chain dehydrogenase 7 197 5.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 3.4E-6 T 12-10-2018 AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 SUPERFAMILY SSF51735 2 251 9.9E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13485 7fc16ffdcceef4f159fae5771a8bea0b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10065 2e04efaee9972a4f6d0fa3b43fb6b52e 140 SUPERFAMILY SSF109635 22 105 3.79E-9 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily AFR_10065 2e04efaee9972a4f6d0fa3b43fb6b52e 140 Gene3D G3DSA:1.20.120.910 6 140 1.9E-32 T 12-10-2018 AFR_10065 2e04efaee9972a4f6d0fa3b43fb6b52e 140 SUPERFAMILY SSF57716 106 139 2.14E-9 T 12-10-2018 AFR_10065 2e04efaee9972a4f6d0fa3b43fb6b52e 140 PRINTS PR00618 DksA/TraR zinc finger signature 121 133 3.8E-5 T 12-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria AFR_10065 2e04efaee9972a4f6d0fa3b43fb6b52e 140 PRINTS PR00618 DksA/TraR zinc finger signature 109 120 3.8E-5 T 12-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria AFR_10065 2e04efaee9972a4f6d0fa3b43fb6b52e 140 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 104 139 4.2E-12 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 AFR_10065 2e04efaee9972a4f6d0fa3b43fb6b52e 140 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 109 133 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site AFR_42110 975cde84866b5fe94ec3fdada94aa0e8 278 Gene3D G3DSA:3.30.200.20 1 84 1.4E-28 T 12-10-2018 AFR_42110 975cde84866b5fe94ec3fdada94aa0e8 278 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 274 23.383 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_42110 975cde84866b5fe94ec3fdada94aa0e8 278 SUPERFAMILY SSF56104 2 277 1.24E-85 T 12-10-2018 AFR_42110 975cde84866b5fe94ec3fdada94aa0e8 278 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 276 6.8E-59 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 AFR_42110 975cde84866b5fe94ec3fdada94aa0e8 278 Gene3D G3DSA:3.30.470.20 85 228 5.5E-47 T 12-10-2018 AFR_42110 975cde84866b5fe94ec3fdada94aa0e8 278 Pfam PF01259 SAICAR synthetase 4 249 1.6E-87 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_19665 9d3ee59d4982d67381d2ea077763cdb0 278 Pfam PF13409 Glutathione S-transferase, N-terminal domain 47 140 2.6E-11 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFR_19665 9d3ee59d4982d67381d2ea077763cdb0 278 Gene3D G3DSA:3.40.30.130 25 160 1.8E-40 T 12-10-2018 AFR_19665 9d3ee59d4982d67381d2ea077763cdb0 278 SUPERFAMILY SSF47616 158 262 9.96E-17 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFR_19665 9d3ee59d4982d67381d2ea077763cdb0 278 SUPERFAMILY SSF52833 34 143 1.16E-6 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_19665 9d3ee59d4982d67381d2ea077763cdb0 278 Gene3D G3DSA:1.20.1050.10 161 273 5.8E-25 T 12-10-2018 AFR_19665 9d3ee59d4982d67381d2ea077763cdb0 278 Pfam PF13410 Glutathione S-transferase, C-terminal domain 185 250 1.2E-9 T 12-10-2018 AFR_38115 7cffa98007780bf122de7efbac324e4d 95 Pfam PF13490 Putative zinc-finger 13 46 5.0E-6 T 12-10-2018 IPR027383 Putative zinc-finger AFR_38115 7cffa98007780bf122de7efbac324e4d 95 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 6 82 7.2E-26 T 12-10-2018 IPR014295 Anti-sigma factor AFR_38115 7cffa98007780bf122de7efbac324e4d 95 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 12 86 8.0E-29 T 12-10-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA AFR_27370 899cf38b5f286b528a216fec96f95808 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 261 9.4E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_27370 899cf38b5f286b528a216fec96f95808 268 SUPERFAMILY SSF161098 3 268 5.05E-68 T 12-10-2018 IPR035906 MetI-like superfamily AFR_27370 899cf38b5f286b528a216fec96f95808 268 Gene3D G3DSA:1.10.3720.10 2 256 1.5E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_31285 1d18deeec025c637006b9eb04608216f 280 SUPERFAMILY SSF46689 213 260 1.93E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_31285 1d18deeec025c637006b9eb04608216f 280 Pfam PF12833 Helix-turn-helix domain 183 260 3.2E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_31285 1d18deeec025c637006b9eb04608216f 280 Gene3D G3DSA:1.10.10.60 170 262 9.2E-21 T 12-10-2018 AFR_31285 1d18deeec025c637006b9eb04608216f 280 SMART SM00342 177 259 4.5E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_02825 73b197325d9ef054b057d7c4bc31bea3 479 Pfam PF13450 NAD(P)-binding Rossmann-like domain 56 121 3.8E-12 T 12-10-2018 AFR_02825 73b197325d9ef054b057d7c4bc31bea3 479 Gene3D G3DSA:3.50.50.60 54 470 1.9E-97 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_02825 73b197325d9ef054b057d7c4bc31bea3 479 Gene3D G3DSA:3.30.70.1990 327 424 1.9E-97 T 12-10-2018 AFR_02825 73b197325d9ef054b057d7c4bc31bea3 479 Gene3D G3DSA:1.10.405.20 123 240 1.9E-97 T 12-10-2018 AFR_02825 73b197325d9ef054b057d7c4bc31bea3 479 SUPERFAMILY SSF51905 53 457 9.71E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_33890 534385f3d89577be8fa12de7b6e90611 317 Gene3D G3DSA:3.40.630.30 2 154 1.3E-24 T 12-10-2018 AFR_33890 534385f3d89577be8fa12de7b6e90611 317 Gene3D G3DSA:3.40.630.30 165 314 9.9E-24 T 12-10-2018 AFR_33890 534385f3d89577be8fa12de7b6e90611 317 SUPERFAMILY SSF55729 178 308 1.03E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_33890 534385f3d89577be8fa12de7b6e90611 317 SUPERFAMILY SSF55729 37 148 1.41E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_33890 534385f3d89577be8fa12de7b6e90611 317 Pfam PF00583 Acetyltransferase (GNAT) family 187 303 1.4E-11 T 12-10-2018 IPR000182 GNAT domain AFR_33890 534385f3d89577be8fa12de7b6e90611 317 Pfam PF00583 Acetyltransferase (GNAT) family 62 144 9.0E-10 T 12-10-2018 IPR000182 GNAT domain AFR_33255 095782fe2059925c5fc00e6bc06874fd 542 SMART SM00637 32 128 6.6E-31 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_33255 095782fe2059925c5fc00e6bc06874fd 542 Gene3D G3DSA:2.60.40.290 29 131 1.8E-28 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_33255 095782fe2059925c5fc00e6bc06874fd 542 SUPERFAMILY SSF49384 28 128 5.09E-28 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_33255 095782fe2059925c5fc00e6bc06874fd 542 Gene3D G3DSA:2.60.110.10 187 522 4.5E-110 T 12-10-2018 IPR037176 Osmotin/thaumatin-like superfamily AFR_33255 095782fe2059925c5fc00e6bc06874fd 542 Pfam PF00553 Cellulose binding domain 33 128 2.0E-24 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_33255 095782fe2059925c5fc00e6bc06874fd 542 Pfam PF16483 Beta-1,3-glucanase 183 538 7.8E-100 T 12-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 AFR_33255 095782fe2059925c5fc00e6bc06874fd 542 Gene3D G3DSA:3.30.920.50 382 496 4.5E-110 T 12-10-2018 AFR_05045 b167ed99c24fbc5da3a7cd50c2010996 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 336 2.0E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_05045 b167ed99c24fbc5da3a7cd50c2010996 343 Pfam PF00005 ABC transporter 41 199 7.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_05045 b167ed99c24fbc5da3a7cd50c2010996 343 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_05045 b167ed99c24fbc5da3a7cd50c2010996 343 SUPERFAMILY SSF52540 49 317 2.82E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05045 b167ed99c24fbc5da3a7cd50c2010996 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 315 3.2E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_05045 b167ed99c24fbc5da3a7cd50c2010996 343 Gene3D G3DSA:3.40.50.300 18 342 1.5E-96 T 12-10-2018 AFR_05045 b167ed99c24fbc5da3a7cd50c2010996 343 SMART SM00382 49 249 1.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_11660 08e04b9551b7baa5ea425004df05964f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.7E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11660 08e04b9551b7baa5ea425004df05964f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.7E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11660 08e04b9551b7baa5ea425004df05964f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.7E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11660 08e04b9551b7baa5ea425004df05964f 300 SUPERFAMILY SSF46785 3 84 8.66E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11660 08e04b9551b7baa5ea425004df05964f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.1E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_11660 08e04b9551b7baa5ea425004df05964f 300 Pfam PF03466 LysR substrate binding domain 103 277 9.0E-28 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_11660 08e04b9551b7baa5ea425004df05964f 300 Gene3D G3DSA:3.40.190.10 161 253 5.2E-29 T 12-10-2018 AFR_11660 08e04b9551b7baa5ea425004df05964f 300 Gene3D G3DSA:1.10.10.10 1 87 5.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11660 08e04b9551b7baa5ea425004df05964f 300 Gene3D G3DSA:3.40.190.10 104 273 5.2E-29 T 12-10-2018 AFR_11660 08e04b9551b7baa5ea425004df05964f 300 SUPERFAMILY SSF53850 103 278 2.17E-26 T 12-10-2018 AFR_17525 725c37c971834d0b3c7c07c99f921589 336 Gene3D G3DSA:3.40.50.2300 66 313 1.6E-66 T 12-10-2018 AFR_17525 725c37c971834d0b3c7c07c99f921589 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 1.3E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_17525 725c37c971834d0b3c7c07c99f921589 336 SUPERFAMILY SSF53822 84 335 8.58E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_17525 725c37c971834d0b3c7c07c99f921589 336 Gene3D G3DSA:3.40.50.2300 174 296 1.6E-66 T 12-10-2018 AFR_17525 725c37c971834d0b3c7c07c99f921589 336 SUPERFAMILY SSF47413 11 69 1.38E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_17525 725c37c971834d0b3c7c07c99f921589 336 Gene3D G3DSA:1.10.260.40 3 65 1.6E-19 T 12-10-2018 AFR_17525 725c37c971834d0b3c7c07c99f921589 336 Pfam PF13377 Periplasmic binding protein-like domain 183 335 2.5E-32 T 12-10-2018 AFR_17525 725c37c971834d0b3c7c07c99f921589 336 SMART SM00354 11 81 1.1E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 SUPERFAMILY SSF89095 349 496 1.44E-23 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 SMART SM00845 349 496 8.5E-60 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 Pfam PF02934 GatB/GatE catalytic domain 19 310 4.5E-103 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 Gene3D G3DSA:1.10.10.410 436 497 1.0E-17 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 163 177 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 Gene3D G3DSA:1.10.150.380 323 433 4.4E-17 T 12-10-2018 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 497 34.772 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 SUPERFAMILY SSF55931 17 318 3.34E-109 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 Pfam PF02637 GatB domain 350 496 4.7E-40 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFR_36970 8c0ee98e293d7f7740df91b950d2f89c 497 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 15 496 4.9E-140 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFR_36920 17608dd51ee150814d76352a08f363e7 333 Gene3D G3DSA:1.10.3720.10 79 329 1.0E-64 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36920 17608dd51ee150814d76352a08f363e7 333 SUPERFAMILY SSF161098 83 319 2.35E-56 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36920 17608dd51ee150814d76352a08f363e7 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 328 2.6E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_42600 16de26a5d20e768ccc498619257c9a63 268 Gene3D G3DSA:3.40.50.1000 5 263 4.4E-60 T 12-10-2018 IPR023214 HAD superfamily AFR_42600 16de26a5d20e768ccc498619257c9a63 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 262 3.7E-52 T 12-10-2018 AFR_42600 16de26a5d20e768ccc498619257c9a63 268 SUPERFAMILY SSF56784 3 266 1.26E-61 T 12-10-2018 IPR036412 HAD-like superfamily AFR_42600 16de26a5d20e768ccc498619257c9a63 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 262 1.1E-46 T 12-10-2018 IPR000150 Cof family GO:0016787 AFR_42600 16de26a5d20e768ccc498619257c9a63 268 Gene3D G3DSA:3.30.1240.10 85 191 4.4E-60 T 12-10-2018 AFR_42600 16de26a5d20e768ccc498619257c9a63 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 235 6.1E-24 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFR_10710 3c5aef74ba56fa081660e0c155b81fb1 280 SUPERFAMILY SSF56529 61 279 2.62E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_10710 3c5aef74ba56fa081660e0c155b81fb1 280 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 71 277 4.7E-66 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFR_10710 3c5aef74ba56fa081660e0c155b81fb1 280 Gene3D G3DSA:3.90.850.10 65 280 1.7E-80 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 SMART SM00345 23 82 2.1E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 Gene3D G3DSA:1.10.10.10 13 83 4.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 SUPERFAMILY SSF46785 16 86 7.4E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 Gene3D G3DSA:3.90.1150.10 114 455 2.0E-74 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 Gene3D G3DSA:3.40.640.10 137 355 2.0E-74 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 Pfam PF00155 Aminotransferase class I and II 117 453 4.5E-26 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 79 9.9E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_10170 08930292ca7c63c68cf2291f6f55864f 475 SUPERFAMILY SSF53383 101 457 1.28E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 1.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 1.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 3.7E-12 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 3.7E-12 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 3.7E-12 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 SUPERFAMILY SSF53474 3 316 2.3E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 PIRSF PIRSF006431 1 319 2.6E-118 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 303 8.5E-98 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 Gene3D G3DSA:3.40.50.1820 1 319 1.2E-89 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21595 b5fd0ac78ab7c5aa136cb1ea5cce3893 326 Pfam PF00561 alpha/beta hydrolase fold 38 300 9.3E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_22835 188f4a594e25c3ba36a67222873af0d3 96 Pfam PF03551 Transcriptional regulator PadR-like family 12 73 1.8E-8 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_22835 188f4a594e25c3ba36a67222873af0d3 96 SUPERFAMILY SSF46785 2 80 2.22E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_22835 188f4a594e25c3ba36a67222873af0d3 96 Gene3D G3DSA:1.10.10.10 1 91 2.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 SUPERFAMILY SSF55031 204 322 6.13E-22 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 PIRSF PIRSF005962 26 414 2.6E-107 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 SUPERFAMILY SSF53187 28 410 2.02E-71 T 12-10-2018 AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 Gene3D G3DSA:3.30.70.360 204 318 1.5E-112 T 12-10-2018 AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 Gene3D G3DSA:3.40.630.10 37 395 1.5E-112 T 12-10-2018 AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 37 395 2.5E-103 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 Pfam PF07687 Peptidase dimerisation domain 208 304 9.4E-7 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFR_39455 e32013d73ef425fcac820c36d1d4ef36 415 Pfam PF01546 Peptidase family M20/M25/M40 93 406 6.6E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_28045 76c4d20942873da44b062c59b9af71e4 733 SUPERFAMILY SSF82866 113 331 1.09E-26 T 12-10-2018 AFR_28045 76c4d20942873da44b062c59b9af71e4 733 Pfam PF03176 MMPL family 394 708 1.9E-33 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_28045 76c4d20942873da44b062c59b9af71e4 733 Pfam PF03176 MMPL family 62 364 6.7E-45 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_28045 76c4d20942873da44b062c59b9af71e4 733 Gene3D G3DSA:1.20.1640.10 255 341 1.5E-6 T 12-10-2018 AFR_28045 76c4d20942873da44b062c59b9af71e4 733 SUPERFAMILY SSF82866 482 701 1.16E-28 T 12-10-2018 AFR_28045 76c4d20942873da44b062c59b9af71e4 733 Gene3D G3DSA:1.20.1640.10 342 388 1.5E-6 T 12-10-2018 AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.160.20.10 899 1279 4.7E-21 T 12-10-2018 IPR012334 Pectin lyase fold AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SUPERFAMILY SSF49265 180 344 2.74E-7 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.60.40.10 272 356 3.7E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.60.40.10 179 265 9.6E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SMART SM00231 35 173 7.4E-16 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.60.40.10 607 730 3.6E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Pfam PF00754 F5/8 type C domain 45 168 4.2E-19 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Pfam PF00754 F5/8 type C domain 371 493 3.8E-7 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SUPERFAMILY SSF49785 361 497 6.31E-16 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.60.120.260 35 178 2.7E-34 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.60.120.260 362 500 3.5E-22 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SUPERFAMILY SSF51126 899 1229 2.22E-25 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.60.120.260 737 881 2.1E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Pfam PF07705 CARDB 615 720 2.0E-6 T 12-10-2018 IPR011635 CARDB domain AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Pfam PF07705 CARDB 502 602 1.4E-22 T 12-10-2018 IPR011635 CARDB domain AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SMART SM00710 1175 1197 530.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SMART SM00710 1208 1238 1700.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SMART SM00710 1049 1071 1300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SMART SM00710 1025 1047 180.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SMART SM00710 1104 1127 2100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 Gene3D G3DSA:2.60.40.10 502 606 1.9E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_33150 a52fd4950b6ef704fae7c9707b8e11f5 1279 SUPERFAMILY SSF49785 35 173 2.62E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 SUPERFAMILY SSF53474 5 232 1.13E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 Gene3D G3DSA:3.40.50.1820 1 234 9.6E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 PRINTS PR00412 Epoxide hydrolase signature 28 43 8.4E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 PRINTS PR00412 Epoxide hydrolase signature 73 86 8.4E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 PRINTS PR00412 Epoxide hydrolase signature 87 100 8.4E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 PRINTS PR00412 Epoxide hydrolase signature 8 26 8.4E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 9.8E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 9.8E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 86 9.8E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_34125 5306a3d2f51b75fd7fbc68137cc59db1 234 Pfam PF12697 Alpha/beta hydrolase family 5 216 5.6E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18885 9ecf14df8c7c0d095520e29060fbbacb 448 Gene3D G3DSA:3.60.21.10 197 442 2.0E-31 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_18885 9ecf14df8c7c0d095520e29060fbbacb 448 SUPERFAMILY SSF56300 222 440 1.36E-34 T 12-10-2018 AFR_18885 9ecf14df8c7c0d095520e29060fbbacb 448 Pfam PF00149 Calcineurin-like phosphoesterase 213 367 3.6E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 562 673 1.5E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Pfam PF00512 His Kinase A (phospho-acceptor) domain 449 517 8.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SUPERFAMILY SSF55874 506 672 2.36E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Gene3D G3DSA:1.10.287.130 443 522 7.4E-17 T 12-10-2018 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SUPERFAMILY SSF55785 144 270 6.28E-12 T 12-10-2018 IPR035965 PAS domain superfamily AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 613 5.5E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 658 671 5.5E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 652 5.5E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SMART SM00388 449 517 6.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Gene3D G3DSA:3.30.450.40 4 141 8.6E-14 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Gene3D G3DSA:3.30.450.40 283 440 9.2E-21 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SMART SM00387 562 674 1.1E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SUPERFAMILY SSF47384 445 517 1.0E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SUPERFAMILY SSF55781 7 141 4.77E-15 T 12-10-2018 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SMART SM00065 2 148 5.4E-4 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SMART SM00065 294 444 4.1E-4 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Pfam PF13185 GAF domain 14 134 6.1E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Pfam PF13185 GAF domain 293 435 7.6E-14 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 SUPERFAMILY SSF55781 264 436 8.57E-18 T 12-10-2018 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Pfam PF08448 PAS fold 159 274 2.5E-10 T 12-10-2018 IPR013656 PAS fold-4 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Gene3D G3DSA:3.30.450.20 142 280 1.2E-18 T 12-10-2018 AFR_31700 70ad1f5211f31a8b0cd1c33676e6834a 675 Gene3D G3DSA:3.30.565.10 523 675 2.0E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_09170 b865bada131e79022d19dc88c911dd17 172 Gene3D G3DSA:3.40.50.300 2 171 1.1E-35 T 12-10-2018 AFR_09170 b865bada131e79022d19dc88c911dd17 172 SUPERFAMILY SSF52540 15 167 2.77E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15270 576bc8b65169d557e099261e12f26ad2 757 SUPERFAMILY SSF48113 453 756 1.92E-107 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 Hamap MF_01961 Catalase-peroxidase [katG]. 17 757 40.159 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 290 313 4.9E-47 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 81 94 4.9E-47 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 96 121 4.9E-47 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 55 77 4.9E-47 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 503 529 4.9E-47 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 Pfam PF00141 Peroxidase 479 730 6.4E-39 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 Pfam PF00141 Peroxidase 113 419 1.9E-44 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 SUPERFAMILY SSF48113 51 451 8.55E-142 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 282 292 - T 12-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 ProSitePatterns PS00436 Peroxidases active site signature. 119 130 - T 12-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 Gene3D G3DSA:1.10.520.10 52 452 6.7E-205 T 12-10-2018 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 50 756 0.0 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 Gene3D G3DSA:1.10.420.20 219 421 6.7E-205 T 12-10-2018 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00458 Haem peroxidase superfamily signature 342 357 1.6E-17 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00458 Haem peroxidase superfamily signature 179 196 1.6E-17 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00458 Haem peroxidase superfamily signature 282 297 1.6E-17 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00458 Haem peroxidase superfamily signature 197 209 1.6E-17 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 PRINTS PR00458 Haem peroxidase superfamily signature 119 133 1.6E-17 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 Gene3D G3DSA:1.10.520.10 456 756 2.6E-143 T 12-10-2018 AFR_15270 576bc8b65169d557e099261e12f26ad2 757 Gene3D G3DSA:1.10.420.10 609 732 2.6E-143 T 12-10-2018 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 28 262 2.1E-30 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 21 360 4.6E-14 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 SUPERFAMILY SSF51419 24 265 9.6E-56 T 12-10-2018 IPR029066 PLP-binding barrel AFR_21240 70377647f9ab613515eeefc2fa44e837 382 SUPERFAMILY SSF50621 236 379 1.57E-32 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 PRINTS PR01182 Ornithine decarboxylase signature 347 360 4.3E-7 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 PRINTS PR01182 Ornithine decarboxylase signature 45 72 4.3E-7 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 PRINTS PR01182 Ornithine decarboxylase signature 87 111 4.3E-7 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 Gene3D G3DSA:3.20.20.10 26 253 5.0E-52 T 12-10-2018 IPR029066 PLP-binding barrel AFR_21240 70377647f9ab613515eeefc2fa44e837 382 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 174 187 1.6E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 252 271 1.6E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 67 79 1.6E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 47 65 1.6E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_21240 70377647f9ab613515eeefc2fa44e837 382 Gene3D G3DSA:2.40.37.10 254 382 1.4E-40 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 Gene3D G3DSA:1.10.357.10 65 203 4.8E-26 T 12-10-2018 AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 5.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 5.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 Pfam PF16925 Bacterial transcriptional repressor C-terminal 90 196 6.9E-11 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 SUPERFAMILY SSF48498 88 203 5.09E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 4.3E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 Gene3D G3DSA:1.10.10.60 3 64 2.9E-18 T 12-10-2018 AFR_18125 1e655ccaa8d297beeb1cf97dabf61ce3 215 SUPERFAMILY SSF46689 8 76 1.85E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_25680 e2f739c953d948a11ffbc23226787734 488 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 297 455 1.9E-36 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_25680 e2f739c953d948a11ffbc23226787734 488 Pfam PF05227 CHASE3 domain 52 171 6.4E-8 T 12-10-2018 IPR007891 CHASE3 AFR_25680 e2f739c953d948a11ffbc23226787734 488 Gene3D G3DSA:1.10.287.950 206 487 2.2E-55 T 12-10-2018 AFR_25680 e2f739c953d948a11ffbc23226787734 488 Gene3D G3DSA:1.20.1440.210 47 180 5.0E-5 T 12-10-2018 AFR_25680 e2f739c953d948a11ffbc23226787734 488 SUPERFAMILY SSF58104 209 485 1.19E-56 T 12-10-2018 AFR_25680 e2f739c953d948a11ffbc23226787734 488 SMART SM00283 226 487 1.1E-53 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 SUPERFAMILY SSF51905 5 370 1.41E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 Gene3D G3DSA:3.50.50.60 8 331 2.4E-65 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 Gene3D G3DSA:3.30.9.50 41 262 2.4E-65 T 12-10-2018 AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 1.2E-18 T 12-10-2018 AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 1.2E-18 T 12-10-2018 AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.2E-18 T 12-10-2018 AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.2E-18 T 12-10-2018 AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 Pfam PF01494 FAD binding domain 5 166 1.8E-11 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_31125 e1b7b55db571aa6ecc2ffb0424b2edc4 396 Pfam PF01494 FAD binding domain 268 333 2.8E-9 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 Gene3D G3DSA:3.40.50.10090 59 195 2.2E-66 T 12-10-2018 AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 SUPERFAMILY SSF69618 28 288 5.62E-56 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 SUPERFAMILY SSF46894 293 380 1.05E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 Pfam PF00486 Transcriptional regulatory protein, C terminal 316 380 1.2E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 Gene3D G3DSA:3.40.50.10090 33 278 2.2E-66 T 12-10-2018 AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 SMART SM00862 311 380 1.1E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 Gene3D G3DSA:1.10.10.10 288 381 1.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04780 fdaf8920c24474ab67e06e1e3c1da3ec 382 Pfam PF02602 Uroporphyrinogen-III synthase HemD 40 279 2.0E-41 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFR_08100 3b6746cfaa0d88dac6793676b4b1648b 113 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 66 1.1E-7 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_08100 3b6746cfaa0d88dac6793676b4b1648b 113 Gene3D G3DSA:3.30.70.100 1 106 2.7E-17 T 12-10-2018 AFR_08100 3b6746cfaa0d88dac6793676b4b1648b 113 SUPERFAMILY SSF54909 2 66 1.24E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_34325 d460ae7e0554a8c753bf61f32c67f917 318 Gene3D G3DSA:3.40.190.10 143 316 5.0E-25 T 12-10-2018 AFR_34325 d460ae7e0554a8c753bf61f32c67f917 318 SUPERFAMILY SSF53850 34 262 1.39E-38 T 12-10-2018 AFR_34325 d460ae7e0554a8c753bf61f32c67f917 318 Pfam PF09084 NMT1/THI5 like 45 261 7.8E-37 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_34325 d460ae7e0554a8c753bf61f32c67f917 318 Gene3D G3DSA:3.40.190.10 33 142 2.6E-14 T 12-10-2018 AFR_17070 1c2318522e3951ec3ad13a1bd0170b60 120 SMART SM00418 17 95 1.4E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_17070 1c2318522e3951ec3ad13a1bd0170b60 120 Gene3D G3DSA:1.10.10.10 8 118 3.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17070 1c2318522e3951ec3ad13a1bd0170b60 120 Pfam PF12840 Helix-turn-helix domain 16 75 1.6E-8 T 12-10-2018 AFR_17070 1c2318522e3951ec3ad13a1bd0170b60 120 SUPERFAMILY SSF46785 14 108 2.35E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 SUPERFAMILY SSF52833 2 137 8.41E-51 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 ProSitePatterns PS00460 Glutathione peroxidases active site. 6 21 - T 12-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 PIRSF PIRSF000303 1 139 1.8E-56 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 PRINTS PR01011 Glutathione peroxidase family signature 99 108 4.3E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 PRINTS PR01011 Glutathione peroxidase family signature 39 55 4.3E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 PRINTS PR01011 Glutathione peroxidase family signature 4 21 4.3E-20 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 Gene3D G3DSA:3.40.30.10 1 139 1.1E-55 T 12-10-2018 AFR_09640 bc5a3994224574cb62ec2112fe01e5d5 139 Pfam PF00255 Glutathione peroxidase 1 92 4.8E-37 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFR_30610 932ee6711480e3d0f6d746e7aedfce01 342 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 4 333 47.14 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AFR_30610 932ee6711480e3d0f6d746e7aedfce01 342 SUPERFAMILY SSF51395 15 331 3.05E-92 T 12-10-2018 AFR_30610 932ee6711480e3d0f6d746e7aedfce01 342 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 11 329 3.5E-116 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AFR_30610 932ee6711480e3d0f6d746e7aedfce01 342 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFR_30610 932ee6711480e3d0f6d746e7aedfce01 342 Gene3D G3DSA:3.20.20.70 3 331 8.8E-124 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_30610 932ee6711480e3d0f6d746e7aedfce01 342 Pfam PF01180 Dihydroorotate dehydrogenase 52 327 1.3E-87 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AFR_30610 932ee6711480e3d0f6d746e7aedfce01 342 PIRSF PIRSF000164 21 338 5.6E-95 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 AFR_42090 3807227dcb494f628f2d98697ab7c79a 130 Pfam PF01042 Endoribonuclease L-PSP 28 129 7.5E-20 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_42090 3807227dcb494f628f2d98697ab7c79a 130 Gene3D G3DSA:3.30.1330.40 2 130 3.3E-30 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_42090 3807227dcb494f628f2d98697ab7c79a 130 SUPERFAMILY SSF55298 8 130 1.19E-27 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_27090 a9fe6cfe580a74b9373f9fb03a11b925 271 SUPERFAMILY SSF53335 13 229 2.09E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_27090 a9fe6cfe580a74b9373f9fb03a11b925 271 Gene3D G3DSA:3.40.50.150 10 270 9.6E-66 T 12-10-2018 AFR_40635 b1b41ca37f36b68bf05691c95057ac84 178 Gene3D G3DSA:3.40.220.10 1 169 3.7E-58 T 12-10-2018 AFR_40635 b1b41ca37f36b68bf05691c95057ac84 178 Pfam PF01661 Macro domain 19 135 2.6E-39 T 12-10-2018 IPR002589 Macro domain AFR_40635 b1b41ca37f36b68bf05691c95057ac84 178 SUPERFAMILY SSF52949 1 160 2.52E-50 T 12-10-2018 AFR_40635 b1b41ca37f36b68bf05691c95057ac84 178 SMART SM00506 2 136 1.3E-48 T 12-10-2018 IPR002589 Macro domain AFR_41675 c7200df872249a5e5008be94d5ba9045 150 SUPERFAMILY SSF89095 3 149 1.78E-31 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFR_41675 c7200df872249a5e5008be94d5ba9045 150 Gene3D G3DSA:1.10.10.410 94 150 4.5E-13 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFR_41675 c7200df872249a5e5008be94d5ba9045 150 Pfam PF09424 Yqey-like protein 5 149 3.1E-43 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 AFR_41675 c7200df872249a5e5008be94d5ba9045 150 Gene3D G3DSA:1.10.1510.10 2 93 9.3E-26 T 12-10-2018 AFR_07000 baffa1e8940740148d175f843358d33f 566 SUPERFAMILY SSF53850 27 307 2.14E-6 T 12-10-2018 AFR_07000 baffa1e8940740148d175f843358d33f 566 SMART SM00327 363 562 2.6E-12 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_07000 baffa1e8940740148d175f843358d33f 566 SUPERFAMILY SSF53300 368 556 1.91E-20 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_07000 baffa1e8940740148d175f843358d33f 566 Gene3D G3DSA:3.40.50.410 366 561 1.3E-26 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_07000 baffa1e8940740148d175f843358d33f 566 Pfam PF13531 Bacterial extracellular solute-binding protein 28 305 1.5E-22 T 12-10-2018 AFR_07000 baffa1e8940740148d175f843358d33f 566 Pfam PF00092 von Willebrand factor type A domain 369 554 6.1E-12 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_36650 7b31f3e79359013846e6d17c24630eee 326 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 1 153 1.0E-46 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 SUPERFAMILY SSF48179 174 326 1.87E-54 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 PIRSF PIRSF000114 1 326 8.5E-99 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 Gene3D G3DSA:3.40.50.720 1 182 4.3E-57 T 12-10-2018 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 183 204 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 317 34.755 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 SUPERFAMILY SSF51735 1 175 1.45E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36650 7b31f3e79359013846e6d17c24630eee 326 Gene3D G3DSA:1.10.1040.10 184 326 1.1E-50 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 193 217 9.0E-44 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 233 250 9.0E-44 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 51 78 9.0E-44 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 1 17 9.0E-44 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 168 192 9.0E-44 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 128 148 9.0E-44 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_36650 7b31f3e79359013846e6d17c24630eee 326 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 175 315 6.0E-51 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 SUPERFAMILY SSF46689 4 65 1.75E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 Gene3D G3DSA:1.10.357.10 62 215 1.0E-31 T 12-10-2018 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 52 1.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 PRINTS PR00400 Tetracycline repressor protein signature 129 148 5.9E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 PRINTS PR00400 Tetracycline repressor protein signature 71 90 5.9E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 PRINTS PR00400 Tetracycline repressor protein signature 20 43 5.9E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 Gene3D G3DSA:1.10.10.60 1 61 8.1E-25 T 12-10-2018 AFR_08610 5a7815a692e7186e03f26177ea11c930 221 SUPERFAMILY SSF48498 69 216 2.67E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_08610 5a7815a692e7186e03f26177ea11c930 221 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 69 213 1.6E-16 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_27800 96c54a4e64dc0bff96e949fbb8b568c9 455 SUPERFAMILY SSF53383 10 450 1.86E-126 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_27800 96c54a4e64dc0bff96e949fbb8b568c9 455 Pfam PF00202 Aminotransferase class-III 32 444 2.8E-96 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27800 96c54a4e64dc0bff96e949fbb8b568c9 455 Gene3D G3DSA:3.40.640.10 65 340 3.8E-156 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_27800 96c54a4e64dc0bff96e949fbb8b568c9 455 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27800 96c54a4e64dc0bff96e949fbb8b568c9 455 Gene3D G3DSA:3.90.1150.10 10 447 3.8E-156 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_27800 96c54a4e64dc0bff96e949fbb8b568c9 455 PIRSF PIRSF000521 21 451 2.0E-24 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_22110 f3d4bd4632d764dbea6ec0fed995a9a9 110 Gene3D G3DSA:3.30.70.1060 2 109 1.8E-6 T 12-10-2018 AFR_22110 f3d4bd4632d764dbea6ec0fed995a9a9 110 SUPERFAMILY SSF54909 4 92 1.23E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 Gene3D G3DSA:3.30.565.10 286 416 1.4E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 SUPERFAMILY SSF55874 292 415 2.62E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 4.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 4.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 415 4.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 PIRSF PIRSF037434 9 420 1.5E-68 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 Pfam PF07730 Histidine kinase 217 283 2.2E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 415 1.2E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_31305 8fa45f6be645b1314a77d9e6181322c7 423 SMART SM00387 321 418 1.2E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 Pfam PF01628 HrcA protein C terminal domain 104 323 2.6E-58 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 Pfam PF08220 DeoR-like helix-turn-helix domain 17 61 3.0E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 330 27.546 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 PIRSF PIRSF005485 1 340 2.5E-101 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 Gene3D G3DSA:3.30.390.60 128 229 6.2E-39 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 Gene3D G3DSA:1.10.10.10 1 85 3.4E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 SUPERFAMILY SSF55781 72 339 8.04E-53 T 12-10-2018 AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 Gene3D G3DSA:3.30.450.40 105 331 6.2E-39 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 336 1.9E-92 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFR_07840 3e076570eeba6b5ba8ed40fc94abbad1 340 SUPERFAMILY SSF46785 3 83 1.44E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_28530 7ce54095050ed91c062b2e5f4b7b8230 218 Gene3D G3DSA:3.40.109.10 1 179 1.2E-42 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_28530 7ce54095050ed91c062b2e5f4b7b8230 218 Pfam PF00881 Nitroreductase family 9 175 8.5E-26 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFR_28530 7ce54095050ed91c062b2e5f4b7b8230 218 SUPERFAMILY SSF55469 4 208 4.06E-44 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_28530 7ce54095050ed91c062b2e5f4b7b8230 218 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 3 201 5.0E-65 T 12-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 PIRSF PIRSF000106 36 415 5.7E-74 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 Gene3D G3DSA:3.40.50.720 166 406 2.4E-72 T 12-10-2018 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 Gene3D G3DSA:3.40.50.10380 11 165 6.9E-71 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 Pfam PF00390 Malic enzyme, N-terminal domain 24 155 1.2E-28 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 SUPERFAMILY SSF53223 17 166 2.88E-55 T 12-10-2018 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 SMART SM00919 168 390 1.2E-99 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 Pfam PF03949 Malic enzyme, NAD binding domain 170 388 1.1E-20 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 SMART SM01274 23 156 3.1E-82 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFR_38020 38c80619f192e5c7362964d2bd187e96 419 SUPERFAMILY SSF51735 168 398 1.58E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15935 5cf09c6084770e0fb50a1cf4ccb9dedc 95 SUPERFAMILY SSF47336 18 94 1.1E-13 T 12-10-2018 IPR036736 ACP-like superfamily AFR_15935 5cf09c6084770e0fb50a1cf4ccb9dedc 95 Gene3D G3DSA:1.10.1200.10 14 94 2.1E-24 T 12-10-2018 IPR036736 ACP-like superfamily AFR_15935 5cf09c6084770e0fb50a1cf4ccb9dedc 95 Pfam PF00550 Phosphopantetheine attachment site 19 89 6.4E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_11800 b9b544d0fdd59bf6643e5f6ceb7463cd 292 Pfam PF00583 Acetyltransferase (GNAT) family 180 265 1.7E-12 T 12-10-2018 IPR000182 GNAT domain AFR_11800 b9b544d0fdd59bf6643e5f6ceb7463cd 292 SUPERFAMILY SSF46785 2 136 4.29E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11800 b9b544d0fdd59bf6643e5f6ceb7463cd 292 Gene3D G3DSA:3.40.630.30 139 286 1.2E-29 T 12-10-2018 AFR_11800 b9b544d0fdd59bf6643e5f6ceb7463cd 292 Pfam PF12802 MarR family 32 85 2.0E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11800 b9b544d0fdd59bf6643e5f6ceb7463cd 292 Gene3D G3DSA:1.10.10.10 1 138 2.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11800 b9b544d0fdd59bf6643e5f6ceb7463cd 292 SUPERFAMILY SSF55729 144 274 1.62E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_11800 b9b544d0fdd59bf6643e5f6ceb7463cd 292 SMART SM00347 26 122 7.1E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 Gene3D G3DSA:3.30.590.40 86 336 3.8E-116 T 12-10-2018 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 SUPERFAMILY SSF54368 6 84 2.09E-12 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 SUPERFAMILY SSF55931 85 329 3.53E-63 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 ProSitePatterns PS00180 Glutamine synthetase signature 1. 37 54 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 SMART SM01230 85 327 2.7E-55 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 Pfam PF00120 Glutamine synthetase, catalytic domain 101 325 3.5E-15 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 Gene3D G3DSA:3.10.20.70 1 85 9.6E-30 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 215 231 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_10915 83a1ef8ec80c06897ee65d6cf9d71b0d 337 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 76 1.8E-12 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_11875 80f943bad07d1823a4fb1f9b20b55f51 266 Pfam PF12697 Alpha/beta hydrolase family 8 254 3.6E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11875 80f943bad07d1823a4fb1f9b20b55f51 266 Gene3D G3DSA:3.40.50.1820 2 265 1.0E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11875 80f943bad07d1823a4fb1f9b20b55f51 266 SUPERFAMILY SSF53474 5 263 2.22E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11875 80f943bad07d1823a4fb1f9b20b55f51 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 1.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11875 80f943bad07d1823a4fb1f9b20b55f51 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 32 47 1.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11875 80f943bad07d1823a4fb1f9b20b55f51 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 1.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_35190 a79774602029815acad6ba839cd59b17 397 SMART SM00474 1 164 7.6E-38 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFR_35190 a79774602029815acad6ba839cd59b17 397 Gene3D G3DSA:1.10.150.80 189 287 4.3E-22 T 12-10-2018 AFR_35190 a79774602029815acad6ba839cd59b17 397 Pfam PF01612 3'-5' exonuclease 1 163 2.8E-37 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFR_35190 a79774602029815acad6ba839cd59b17 397 Pfam PF00570 HRDC domain 210 274 7.5E-13 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFR_35190 a79774602029815acad6ba839cd59b17 397 Gene3D G3DSA:1.10.150.80 293 385 2.2E-24 T 12-10-2018 AFR_35190 a79774602029815acad6ba839cd59b17 397 SUPERFAMILY SSF47819 188 292 8.07E-22 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 AFR_35190 a79774602029815acad6ba839cd59b17 397 Gene3D G3DSA:3.30.420.10 1 188 4.7E-69 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_35190 a79774602029815acad6ba839cd59b17 397 SMART SM00341 205 285 3.0E-16 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFR_35190 a79774602029815acad6ba839cd59b17 397 SUPERFAMILY SSF53098 1 203 3.63E-53 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_41030 5c525b30e3ff90f930e098d2ee2863a3 375 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 38 360 2.6E-77 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 AFR_41030 5c525b30e3ff90f930e098d2ee2863a3 375 Pfam PF01979 Amidohydrolase family 40 365 3.3E-28 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_41030 5c525b30e3ff90f930e098d2ee2863a3 375 SUPERFAMILY SSF51338 7 366 4.32E-8 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_41030 5c525b30e3ff90f930e098d2ee2863a3 375 Gene3D G3DSA:2.30.40.10 36 363 4.1E-118 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_41030 5c525b30e3ff90f930e098d2ee2863a3 375 PIRSF PIRSF038994 23 367 1.4E-107 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 AFR_41030 5c525b30e3ff90f930e098d2ee2863a3 375 Gene3D G3DSA:3.20.20.140 44 337 4.1E-118 T 12-10-2018 AFR_41030 5c525b30e3ff90f930e098d2ee2863a3 375 SUPERFAMILY SSF51556 44 337 1.7E-91 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_23915 34067ba813b5cb1a1a681c5032f3b286 188 SUPERFAMILY SSF88659 105 166 1.27E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_23915 34067ba813b5cb1a1a681c5032f3b286 188 Pfam PF04542 Sigma-70 region 2 15 78 3.6E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23915 34067ba813b5cb1a1a681c5032f3b286 188 Pfam PF08281 Sigma-70, region 4 110 161 1.5E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_23915 34067ba813b5cb1a1a681c5032f3b286 188 SUPERFAMILY SSF88946 6 93 4.71E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23915 34067ba813b5cb1a1a681c5032f3b286 188 Gene3D G3DSA:1.10.1740.10 1 78 1.2E-11 T 12-10-2018 AFR_23915 34067ba813b5cb1a1a681c5032f3b286 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 163 3.3E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_23915 34067ba813b5cb1a1a681c5032f3b286 188 Gene3D G3DSA:1.10.10.10 87 167 3.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 Gene3D G3DSA:3.30.360.10 175 452 1.1E-133 T 12-10-2018 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 SUPERFAMILY SSF51735 4 188 5.91E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 PIRSF PIRSF000110 1 462 1.5E-124 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 175 181 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 312 338 4.5E-35 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 141 154 4.5E-35 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 165 193 4.5E-35 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 217 234 4.5E-35 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 235 251 4.5E-35 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 Gene3D G3DSA:3.40.50.720 8 416 1.1E-133 T 12-10-2018 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 5 456 1.2E-120 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 5 464 74.802 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 188 459 2.9E-76 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 SUPERFAMILY SSF55347 175 461 1.5E-83 T 12-10-2018 AFR_19085 33f5a676fe2c07f8b0e7d09ccf5da9d1 464 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 185 2.3E-43 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_35170 aa371c0c7adefc5d4b14d19f0bf093ac 464 SUPERFAMILY SSF51905 3 315 5.18E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_35170 aa371c0c7adefc5d4b14d19f0bf093ac 464 SUPERFAMILY SSF54373 301 409 7.46E-21 T 12-10-2018 AFR_35170 aa371c0c7adefc5d4b14d19f0bf093ac 464 Pfam PF01593 Flavin containing amine oxidoreductase 12 458 4.8E-38 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_35170 aa371c0c7adefc5d4b14d19f0bf093ac 464 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 201 7.5E-32 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFR_35170 aa371c0c7adefc5d4b14d19f0bf093ac 464 Gene3D G3DSA:3.50.50.60 6 450 1.6E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_35170 aa371c0c7adefc5d4b14d19f0bf093ac 464 Gene3D G3DSA:1.10.3110.10 109 198 1.6E-105 T 12-10-2018 AFR_35170 aa371c0c7adefc5d4b14d19f0bf093ac 464 Gene3D G3DSA:3.90.660.20 38 408 1.6E-105 T 12-10-2018 AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 SUPERFAMILY SSF53383 31 484 5.47E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 84 417 8.9E-44 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 Gene3D G3DSA:3.40.640.10 115 361 3.7E-114 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 128 147 1.3E-8 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 88 107 1.3E-8 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 399 418 1.3E-8 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 356 371 1.3E-8 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 AFR_17080 4f87998ee18996ac3fe6e14f379cc044 490 Gene3D G3DSA:3.90.1150.170 40 468 3.7E-114 T 12-10-2018 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.3E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.3E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.3E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 SUPERFAMILY SSF52172 1 136 7.26E-17 T 12-10-2018 IPR011006 CheY-like superfamily AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 SMART SM00421 148 211 3.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 Pfam PF00072 Response regulator receiver domain 3 108 5.9E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 SMART SM00448 1 120 1.3E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 Gene3D G3DSA:3.40.50.12740 1 207 2.4E-41 T 12-10-2018 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 SUPERFAMILY SSF46894 132 196 2.89E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 5.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30370 0e02e9cfeb435dffd72786e4f9abdcb1 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27765 fa52af66ece2b5ca88c5bc0798a4956f 543 Gene3D G3DSA:3.50.50.60 8 531 1.1E-144 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27765 fa52af66ece2b5ca88c5bc0798a4956f 543 Gene3D G3DSA:3.90.700.10 326 469 1.1E-144 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_27765 fa52af66ece2b5ca88c5bc0798a4956f 543 SUPERFAMILY SSF56425 322 480 2.27E-30 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_27765 fa52af66ece2b5ca88c5bc0798a4956f 543 Pfam PF00890 FAD binding domain 10 520 6.1E-75 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_27765 fa52af66ece2b5ca88c5bc0798a4956f 543 SUPERFAMILY SSF51905 6 540 9.15E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_16300 dd93c1d34d3e75bcd8c1d83a541140e1 370 Pfam PF07728 AAA domain (dynein-related subfamily) 80 220 4.8E-35 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFR_16300 dd93c1d34d3e75bcd8c1d83a541140e1 370 Gene3D G3DSA:3.40.50.300 61 239 1.2E-24 T 12-10-2018 AFR_16300 dd93c1d34d3e75bcd8c1d83a541140e1 370 SUPERFAMILY SSF52540 51 267 4.85E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08405 128fa677effa77b9d71be5f275cdfc40 336 SUPERFAMILY SSF52980 220 320 3.75E-6 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_08405 128fa677effa77b9d71be5f275cdfc40 336 Gene3D G3DSA:3.40.960.10 216 322 5.3E-17 T 12-10-2018 AFR_08405 128fa677effa77b9d71be5f275cdfc40 336 Pfam PF04480 Protein of unknown function (DUF559) 255 318 1.7E-10 T 12-10-2018 IPR007569 Protein of unknown function DUF559 AFR_08595 95a89bceca228ae71a541d6853049502 280 Pfam PF01975 Survival protein SurE 5 209 5.8E-42 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFR_08595 95a89bceca228ae71a541d6853049502 280 Gene3D G3DSA:3.40.1210.10 4 277 3.3E-58 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFR_08595 95a89bceca228ae71a541d6853049502 280 SUPERFAMILY SSF64167 4 264 5.23E-44 T 12-10-2018 AFR_21405 4d6c52a73e494b62e61f61ae8e638f6a 211 Gene3D G3DSA:3.10.180.10 93 209 4.4E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21405 4d6c52a73e494b62e61f61ae8e638f6a 211 SUPERFAMILY SSF54593 115 207 6.31E-7 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_15900 b3f0a1db339b4733c2f66753d082f64a 321 Gene3D G3DSA:3.90.25.10 186 318 9.9E-87 T 12-10-2018 AFR_15900 b3f0a1db339b4733c2f66753d082f64a 321 SUPERFAMILY SSF51735 7 319 1.69E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15900 b3f0a1db339b4733c2f66753d082f64a 321 Gene3D G3DSA:3.40.50.720 12 307 9.9E-87 T 12-10-2018 AFR_15900 b3f0a1db339b4733c2f66753d082f64a 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 249 1.4E-49 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 Gene3D G3DSA:1.20.120.530 77 210 4.9E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 SMART SM00895 83 207 5.2E-12 T 12-10-2018 IPR011711 GntR, C-terminal AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 Pfam PF07729 FCD domain 83 206 2.2E-15 T 12-10-2018 IPR011711 GntR, C-terminal AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 73 1.0E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.9E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.9E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 Gene3D G3DSA:1.10.10.10 7 74 1.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 SUPERFAMILY SSF48008 79 207 1.75E-20 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 SMART SM00345 15 73 2.4E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_34345 ac18446dbf2c38718efb9845d143bc65 211 SUPERFAMILY SSF46785 8 77 9.1E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 PIRSF PIRSF006337 1 575 2.1E-227 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 Pfam PF00128 Alpha amylase, catalytic domain 111 200 2.2E-11 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 Gene3D G3DSA:2.60.40.10 1 83 4.5E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 SUPERFAMILY SSF81296 2 77 2.57E-13 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 540 8.0E-225 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 Pfam PF11941 Domain of unknown function (DUF3459) 489 573 4.9E-13 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 SUPERFAMILY SSF51445 74 503 8.18E-109 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 Gene3D G3DSA:3.20.20.80 87 498 3.1E-168 T 12-10-2018 AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 Gene3D G3DSA:1.10.10.760 430 470 3.1E-168 T 12-10-2018 AFR_31585 9fefd9f82beb1d40327fbb616bc4d815 577 SMART SM00642 99 445 2.4E-9 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_16260 5c81b2cd2ea7c88aa51721e90757c20c 58 Pfam PF08410 Domain of unknown function (DUF1737) 9 55 8.7E-20 T 12-10-2018 IPR013619 Domain of unknown function DUF1737 AFR_19200 befa1b3f7d471ed0332d165cb669023b 313 SUPERFAMILY SSF103481 183 283 1.44E-8 T 12-10-2018 AFR_19200 befa1b3f7d471ed0332d165cb669023b 313 Pfam PF00892 EamA-like transporter family 12 137 2.8E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_19200 befa1b3f7d471ed0332d165cb669023b 313 Pfam PF00892 EamA-like transporter family 147 279 5.8E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_19200 befa1b3f7d471ed0332d165cb669023b 313 SUPERFAMILY SSF103481 38 142 4.18E-9 T 12-10-2018 AFR_41840 934dfc4ac604a78f34801454225ac711 113 Gene3D G3DSA:3.30.750.24 1 112 6.4E-29 T 12-10-2018 IPR036513 STAS domain superfamily AFR_41840 934dfc4ac604a78f34801454225ac711 113 SUPERFAMILY SSF52091 7 109 2.55E-23 T 12-10-2018 IPR036513 STAS domain superfamily AFR_41840 934dfc4ac604a78f34801454225ac711 113 Pfam PF13466 STAS domain 15 95 5.6E-16 T 12-10-2018 IPR002645 STAS domain AFR_41840 934dfc4ac604a78f34801454225ac711 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 6 105 1.9E-19 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_00310 c64410177dc0fe413c2dbc6d5b9fd126 677 Gene3D G3DSA:2.40.260.10 479 667 1.1E-50 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_00310 c64410177dc0fe413c2dbc6d5b9fd126 677 Pfam PF04203 Sortase family 527 654 2.7E-31 T 12-10-2018 IPR005754 Sortase family AFR_00310 c64410177dc0fe413c2dbc6d5b9fd126 677 TIGRFAM TIGR01076 sortase_fam: sortase 525 657 4.3E-15 T 12-10-2018 IPR005754 Sortase family AFR_00310 c64410177dc0fe413c2dbc6d5b9fd126 677 SUPERFAMILY SSF63817 517 657 2.22E-31 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_35770 948bcead9d549c6f25275f90437ec839 206 Gene3D G3DSA:1.20.120.520 1 149 9.4E-27 T 12-10-2018 AFR_35770 948bcead9d549c6f25275f90437ec839 206 Pfam PF01814 Hemerythrin HHE cation binding domain 3 131 2.4E-16 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFR_32145 e2c853941144dc732c5e6d8a465552d2 417 Pfam PF13546 DDE superfamily endonuclease 21 290 1.4E-85 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain AFR_32145 e2c853941144dc732c5e6d8a465552d2 417 SUPERFAMILY SSF53098 34 410 5.01E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_37165 e2c853941144dc732c5e6d8a465552d2 417 Pfam PF13546 DDE superfamily endonuclease 21 290 1.4E-85 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain AFR_37165 e2c853941144dc732c5e6d8a465552d2 417 SUPERFAMILY SSF53098 34 410 5.01E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_23585 e2c853941144dc732c5e6d8a465552d2 417 Pfam PF13546 DDE superfamily endonuclease 21 290 1.4E-85 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain AFR_23585 e2c853941144dc732c5e6d8a465552d2 417 SUPERFAMILY SSF53098 34 410 5.01E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_04330 e2c853941144dc732c5e6d8a465552d2 417 Pfam PF13546 DDE superfamily endonuclease 21 290 1.4E-85 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain AFR_04330 e2c853941144dc732c5e6d8a465552d2 417 SUPERFAMILY SSF53098 34 410 5.01E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_27705 e2c853941144dc732c5e6d8a465552d2 417 Pfam PF13546 DDE superfamily endonuclease 21 290 1.4E-85 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain AFR_27705 e2c853941144dc732c5e6d8a465552d2 417 SUPERFAMILY SSF53098 34 410 5.01E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_34785 e2c853941144dc732c5e6d8a465552d2 417 Pfam PF13546 DDE superfamily endonuclease 21 290 1.4E-85 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain AFR_34785 e2c853941144dc732c5e6d8a465552d2 417 SUPERFAMILY SSF53098 34 410 5.01E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 Pfam PF00175 Oxidoreductase NAD-binding domain 333 429 2.3E-7 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 Gene3D G3DSA:3.40.50.80 327 451 8.5E-24 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 SUPERFAMILY SSF52343 312 446 4.85E-25 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 PRINTS PR00410 Phenol hydroxylase reductase family signature 332 351 2.3E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 PRINTS PR00410 Phenol hydroxylase reductase family signature 416 424 2.3E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 PRINTS PR00410 Phenol hydroxylase reductase family signature 316 325 2.3E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 PRINTS PR00410 Phenol hydroxylase reductase family signature 256 268 2.3E-10 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 Pfam PF01794 Ferric reductase like transmembrane component 64 180 8.9E-18 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 SUPERFAMILY SSF63380 222 321 1.24E-15 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_19815 5a8ce20d6c6c87e5f812076f6a424125 452 Gene3D G3DSA:2.40.30.10 222 320 6.0E-13 T 12-10-2018 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 289 9.5E-48 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 Gene3D G3DSA:3.30.70.260 323 403 1.2E-26 T 12-10-2018 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 321 2.5E-32 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 SUPERFAMILY SSF51735 103 290 7.68E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 Gene3D G3DSA:3.40.50.720 10 307 9.2E-102 T 12-10-2018 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 SUPERFAMILY SSF52283 4 133 1.34E-40 T 12-10-2018 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 SUPERFAMILY SSF55021 329 403 4.87E-14 T 12-10-2018 AFR_07165 70f5ced81adf74b88d14ee0d3e03cc38 403 Gene3D G3DSA:3.40.50.720 104 292 9.2E-102 T 12-10-2018 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 SUPERFAMILY SSF52317 551 667 1.21E-9 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 Pfam PF06628 Catalase-related immune-responsive 459 521 1.3E-20 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 Gene3D G3DSA:2.40.180.10 1 452 2.0E-194 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 SMART SM01060 44 433 4.2E-254 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 Pfam PF00199 Catalase 44 429 8.9E-168 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 375 383 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 Gene3D G3DSA:3.40.50.880 551 697 2.6E-28 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 Gene3D G3DSA:1.20.1370.20 456 550 5.1E-28 T 12-10-2018 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 SUPERFAMILY SSF56634 38 529 8.51E-207 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 ProSitePatterns PS00438 Catalase proximal active site signature. 80 96 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 PRINTS PR00067 Catalase signature 57 80 7.3E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 PRINTS PR00067 Catalase signature 141 158 7.3E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 PRINTS PR00067 Catalase signature 330 357 7.3E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 PRINTS PR00067 Catalase signature 160 178 7.3E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 PRINTS PR00067 Catalase signature 362 388 7.3E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 PRINTS PR00067 Catalase signature 120 138 7.3E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_20410 08c129c6ff31d4c768d2cd4bdc24637a 699 PIRSF PIRSF038927 14 698 1.2E-295 T 12-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 AFR_28985 40f2f4f3aa773d22d9dab07061e85356 244 SUPERFAMILY SSF53474 2 230 1.49E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28985 40f2f4f3aa773d22d9dab07061e85356 244 Gene3D G3DSA:3.40.50.1820 1 232 1.2E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28985 40f2f4f3aa773d22d9dab07061e85356 244 Pfam PF12697 Alpha/beta hydrolase family 5 225 9.7E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 SMART SM00862 16 88 4.3E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 SUPERFAMILY SSF52540 229 509 5.84E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 SUPERFAMILY SSF48452 784 908 2.05E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 Pfam PF03704 Bacterial transcriptional activator domain 108 220 4.4E-25 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 72 2.7E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 SMART SM01043 95 222 1.0E-33 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 Gene3D G3DSA:1.25.40.10 730 1022 5.0E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 Gene3D G3DSA:1.10.10.10 1 90 3.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 SUPERFAMILY SSF48452 91 237 4.86E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 SUPERFAMILY SSF46894 2 88 3.68E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 Gene3D G3DSA:1.25.40.10 92 238 1.2E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 PRINTS PR00364 Disease resistance protein signature 443 457 7.1E-6 T 12-10-2018 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 PRINTS PR00364 Disease resistance protein signature 340 354 7.1E-6 T 12-10-2018 AFR_09100 2f20f7351d3d9b1b7b3e842debd95216 1023 PRINTS PR00364 Disease resistance protein signature 259 274 7.1E-6 T 12-10-2018 AFR_18670 9d0a6e61c80fe72aedb2bab57ef36227 220 SUPERFAMILY SSF53800 5 208 3.6E-26 T 12-10-2018 AFR_18670 9d0a6e61c80fe72aedb2bab57ef36227 220 Gene3D G3DSA:3.40.50.1400 5 108 9.9E-25 T 12-10-2018 AFR_18670 9d0a6e61c80fe72aedb2bab57ef36227 220 Gene3D G3DSA:3.40.50.1400 109 212 4.0E-16 T 12-10-2018 AFR_18670 9d0a6e61c80fe72aedb2bab57ef36227 220 Pfam PF01903 CbiX 12 103 1.2E-14 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFR_18670 9d0a6e61c80fe72aedb2bab57ef36227 220 Pfam PF01903 CbiX 118 181 1.4E-5 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFR_32015 47402f74039ba36e178ea7c5f51cab4d 293 Pfam PF13560 Helix-turn-helix domain 14 73 1.2E-13 T 12-10-2018 AFR_32015 47402f74039ba36e178ea7c5f51cab4d 293 SMART SM00530 17 72 5.8E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_32015 47402f74039ba36e178ea7c5f51cab4d 293 Gene3D G3DSA:1.10.260.40 14 99 2.5E-11 T 12-10-2018 AFR_32015 47402f74039ba36e178ea7c5f51cab4d 293 SUPERFAMILY SSF47413 12 74 2.55E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_41835 2176837df02df2894f994f776a59e77e 200 SUPERFAMILY SSF46785 13 101 1.5E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41835 2176837df02df2894f994f776a59e77e 200 Pfam PF12840 Helix-turn-helix domain 16 70 1.7E-10 T 12-10-2018 AFR_41835 2176837df02df2894f994f776a59e77e 200 SMART SM00418 16 113 0.0025 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_41835 2176837df02df2894f994f776a59e77e 200 Gene3D G3DSA:1.10.10.10 15 128 4.3E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 PRINTS PR00400 Tetracycline repressor protein signature 14 37 4.8E-26 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 PRINTS PR00400 Tetracycline repressor protein signature 169 183 4.8E-26 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 PRINTS PR00400 Tetracycline repressor protein signature 87 110 4.8E-26 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 PRINTS PR00400 Tetracycline repressor protein signature 122 141 4.8E-26 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 PRINTS PR00400 Tetracycline repressor protein signature 67 86 4.8E-26 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 61 185 7.3E-21 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 Gene3D G3DSA:1.10.357.10 56 187 1.3E-29 T 12-10-2018 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 SUPERFAMILY SSF46689 2 51 2.46E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 2 15 3.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 46 3.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 3.1E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 Gene3D G3DSA:1.10.10.60 1 55 8.7E-23 T 12-10-2018 AFR_37125 ff9f977a08516d32e7e1e1c83e44e331 197 SUPERFAMILY SSF48498 60 188 6.56E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_01930 f0e1672f162180e34b42e58fe988e4f1 397 SMART SM00382 39 181 0.0013 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01930 f0e1672f162180e34b42e58fe988e4f1 397 SUPERFAMILY SSF52540 4 220 7.71E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01930 f0e1672f162180e34b42e58fe988e4f1 397 Gene3D G3DSA:3.40.50.300 1 179 1.3E-45 T 12-10-2018 AFR_01930 f0e1672f162180e34b42e58fe988e4f1 397 Pfam PF13177 DNA polymerase III, delta subunit 33 180 5.8E-34 T 12-10-2018 AFR_01930 f0e1672f162180e34b42e58fe988e4f1 397 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 35 215 3.9E-55 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFR_41405 3a3a3552185a7a9a823bc47e519cfc88 374 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 128 298 1.8E-51 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_41405 3a3a3552185a7a9a823bc47e519cfc88 374 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 300 374 2.2E-19 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_41405 3a3a3552185a7a9a823bc47e519cfc88 374 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 6 374 41.156 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_41405 3a3a3552185a7a9a823bc47e519cfc88 374 SUPERFAMILY SSF56762 23 373 1.44E-103 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_41405 3a3a3552185a7a9a823bc47e519cfc88 374 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 50 61 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_41405 3a3a3552185a7a9a823bc47e519cfc88 374 Gene3D G3DSA:1.10.645.20 14 374 4.4E-138 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 SUPERFAMILY SSF53822 66 330 1.1E-52 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 55 4.0E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 SMART SM00354 5 78 1.2E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 Gene3D G3DSA:3.40.50.2300 169 298 1.5E-60 T 12-10-2018 AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 Gene3D G3DSA:3.40.50.2300 62 313 1.5E-60 T 12-10-2018 AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 SUPERFAMILY SSF47413 7 63 1.77E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 Pfam PF13377 Periplasmic binding protein-like domain 182 336 6.4E-29 T 12-10-2018 AFR_38485 94ce1beca1c5656fc17867138e2248d8 339 Gene3D G3DSA:1.10.260.40 2 61 2.6E-20 T 12-10-2018 AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 Gene3D G3DSA:1.20.1250.20 1 411 1.7E-19 T 12-10-2018 AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 Gene3D G3DSA:3.40.50.300 445 654 8.5E-66 T 12-10-2018 AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 SUPERFAMILY SSF52540 447 649 1.55E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 Pfam PF02223 Thymidylate kinase 453 642 4.3E-47 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 Hamap MF_00165 Thymidylate kinase [tmk]. 449 653 30.774 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 ProSitePatterns PS01331 Thymidylate kinase signature. 540 552 - T 12-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 447 643 2.8E-51 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFR_01925 a00e7d72e446ba046d083fd3354a15a5 1034 SUPERFAMILY SSF103473 3 415 4.45E-23 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_39795 0e0436f4c45061f9f87362eb7e9f7874 191 SUPERFAMILY SSF52980 21 189 6.97E-22 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_39795 0e0436f4c45061f9f87362eb7e9f7874 191 Gene3D G3DSA:3.90.1570.10 17 190 7.2E-21 T 12-10-2018 AFR_39795 0e0436f4c45061f9f87362eb7e9f7874 191 Pfam PF05685 Putative restriction endonuclease 25 174 1.8E-24 T 12-10-2018 IPR008538 Domain of unknown function DUF820 AFR_16775 4423f3c4285ea53b58dcd416ec94b054 331 Gene3D G3DSA:2.40.10.240 60 164 8.1E-60 T 12-10-2018 AFR_16775 4423f3c4285ea53b58dcd416ec94b054 331 Pfam PF02547 Queuosine biosynthesis protein 3 329 9.7E-75 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFR_16775 4423f3c4285ea53b58dcd416ec94b054 331 SUPERFAMILY SSF111337 3 330 1.83E-75 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFR_16775 4423f3c4285ea53b58dcd416ec94b054 331 Gene3D G3DSA:3.40.1780.10 12 328 8.1E-60 T 12-10-2018 AFR_00695 0816fe560142807edf5cbf2af3b89101 165 SMART SM00418 1 80 6.9E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_00695 0816fe560142807edf5cbf2af3b89101 165 Gene3D G3DSA:1.10.10.10 1 70 2.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00695 0816fe560142807edf5cbf2af3b89101 165 SUPERFAMILY SSF46785 1 139 1.34E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_00695 0816fe560142807edf5cbf2af3b89101 165 Pfam PF12840 Helix-turn-helix domain 1 54 2.1E-13 T 12-10-2018 AFR_04100 51d64b4a5064c8ac7fc3324f9c4aebba 97 Pfam PF10615 Protein of unknown function (DUF2470) 9 83 3.8E-18 T 12-10-2018 IPR019595 Domain of unknown function DUF2470 AFR_04100 51d64b4a5064c8ac7fc3324f9c4aebba 97 SUPERFAMILY SSF50475 9 88 2.24E-8 T 12-10-2018 AFR_04100 51d64b4a5064c8ac7fc3324f9c4aebba 97 Gene3D G3DSA:3.20.180.10 2 89 8.7E-27 T 12-10-2018 IPR037119 Haem oxygenase HugZ-like superfamily AFR_15310 da8e6a8fb5df801a1dfa3382adddb2c2 431 Pfam PF01547 Bacterial extracellular solute-binding protein 51 334 1.4E-26 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_15310 da8e6a8fb5df801a1dfa3382adddb2c2 431 Gene3D G3DSA:3.40.190.10 55 348 4.2E-43 T 12-10-2018 AFR_15310 da8e6a8fb5df801a1dfa3382adddb2c2 431 SUPERFAMILY SSF53850 18 363 9.32E-45 T 12-10-2018 AFR_15310 da8e6a8fb5df801a1dfa3382adddb2c2 431 Gene3D G3DSA:3.40.190.10 143 307 4.2E-43 T 12-10-2018 AFR_14130 2ad630d20c9c1360b00b50b0146f243e 94 Pfam PF11239 Protein of unknown function (DUF3040) 2 75 3.0E-12 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 AFR_29375 9dc57e9fd8ddb72803787c1608b1dbd5 413 Pfam PF12323 Helix-turn-helix domain 5 48 5.9E-15 T 12-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFR_29375 9dc57e9fd8ddb72803787c1608b1dbd5 413 Pfam PF07282 Putative transposase DNA-binding domain 301 368 1.6E-18 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_29375 9dc57e9fd8ddb72803787c1608b1dbd5 413 Pfam PF01385 Probable transposase 176 286 1.2E-22 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFR_29375 9dc57e9fd8ddb72803787c1608b1dbd5 413 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 257 328 2.3E-6 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_40790 f0bff173ae2dda3229057bb7dd3358b1 328 SUPERFAMILY SSF51735 5 160 2.48E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40790 f0bff173ae2dda3229057bb7dd3358b1 328 Gene3D G3DSA:3.40.50.720 4 159 3.6E-43 T 12-10-2018 AFR_40790 f0bff173ae2dda3229057bb7dd3358b1 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 125 5.6E-21 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_40790 f0bff173ae2dda3229057bb7dd3358b1 328 Gene3D G3DSA:3.30.360.10 160 328 7.9E-52 T 12-10-2018 AFR_40790 f0bff173ae2dda3229057bb7dd3358b1 328 SUPERFAMILY SSF55347 133 296 8.83E-40 T 12-10-2018 AFR_26950 8b500cc49df65a6d532a855e3c7af9f2 101 Pfam PF01022 Bacterial regulatory protein, arsR family 12 57 5.1E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26950 8b500cc49df65a6d532a855e3c7af9f2 101 SUPERFAMILY SSF46785 4 98 5.87E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26950 8b500cc49df65a6d532a855e3c7af9f2 101 SMART SM00418 4 82 1.5E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26950 8b500cc49df65a6d532a855e3c7af9f2 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 1.1E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26950 8b500cc49df65a6d532a855e3c7af9f2 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 1.1E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26950 8b500cc49df65a6d532a855e3c7af9f2 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 1.1E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26950 8b500cc49df65a6d532a855e3c7af9f2 101 Gene3D G3DSA:1.10.10.10 3 101 1.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_41515 0ee3b12d7df27c5bf78d474e3370030e 861 Pfam PF01580 FtsK/SpoIIIE family 344 525 2.2E-16 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_41515 0ee3b12d7df27c5bf78d474e3370030e 861 Gene3D G3DSA:3.40.50.300 313 566 1.6E-49 T 12-10-2018 AFR_41515 0ee3b12d7df27c5bf78d474e3370030e 861 SUPERFAMILY SSF52540 328 551 1.17E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41515 0ee3b12d7df27c5bf78d474e3370030e 861 Gene3D G3DSA:3.40.50.300 119 267 8.0E-7 T 12-10-2018 AFR_21435 47772baaa9fce085f893bcda4682055c 773 Gene3D G3DSA:1.25.40.10 577 767 7.3E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_21435 47772baaa9fce085f893bcda4682055c 773 Gene3D G3DSA:1.25.40.10 458 575 2.5E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_21435 47772baaa9fce085f893bcda4682055c 773 Pfam PF00931 NB-ARC domain 103 288 2.3E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 AFR_21435 47772baaa9fce085f893bcda4682055c 773 SUPERFAMILY SSF48452 540 743 2.45E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_21435 47772baaa9fce085f893bcda4682055c 773 SMART SM00028 681 714 32.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_21435 47772baaa9fce085f893bcda4682055c 773 SMART SM00028 522 555 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_21435 47772baaa9fce085f893bcda4682055c 773 SMART SM00028 601 634 90.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_21435 47772baaa9fce085f893bcda4682055c 773 SMART SM00028 641 674 93.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_21435 47772baaa9fce085f893bcda4682055c 773 SUPERFAMILY SSF52540 78 332 1.45E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21435 47772baaa9fce085f893bcda4682055c 773 Gene3D G3DSA:3.40.50.300 74 225 1.1E-15 T 12-10-2018 AFR_21435 47772baaa9fce085f893bcda4682055c 773 PRINTS PR00364 Disease resistance protein signature 182 196 1.4E-7 T 12-10-2018 AFR_21435 47772baaa9fce085f893bcda4682055c 773 PRINTS PR00364 Disease resistance protein signature 267 281 1.4E-7 T 12-10-2018 AFR_21435 47772baaa9fce085f893bcda4682055c 773 PRINTS PR00364 Disease resistance protein signature 105 120 1.4E-7 T 12-10-2018 AFR_11440 7dec60bab54949451df0dae20fa1d1c7 339 SUPERFAMILY SSF51430 1 317 5.63E-98 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_11440 7dec60bab54949451df0dae20fa1d1c7 339 Pfam PF00248 Aldo/keto reductase family 16 318 1.9E-70 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_11440 7dec60bab54949451df0dae20fa1d1c7 339 Gene3D G3DSA:3.20.20.100 1 336 4.8E-115 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 Gene3D G3DSA:3.40.50.720 1 277 3.4E-92 T 12-10-2018 AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 SUPERFAMILY SSF51735 36 276 3.54E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 46 275 2.8E-64 T 12-10-2018 AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 185 204 1.9E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 113 124 1.9E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 173 1.9E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 38 55 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 124 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 240 260 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 175 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23535 7cf05309f0aee98df75cd59238fa0a85 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 172 200 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 450 3.2E-13 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 2.4E-11 T 12-10-2018 IPR000362 Fumarate lyase family AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 2.4E-11 T 12-10-2018 IPR000362 Fumarate lyase family AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 2.4E-11 T 12-10-2018 IPR000362 Fumarate lyase family AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.4E-11 T 12-10-2018 IPR000362 Fumarate lyase family AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 Gene3D G3DSA:1.10.275.60 21 230 1.2E-140 T 12-10-2018 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 Gene3D G3DSA:1.20.200.10 10 447 1.2E-140 T 12-10-2018 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 SMART SM00998 365 451 1.1E-21 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 SUPERFAMILY SSF48557 6 452 2.2E-85 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 7 450 2.3E-127 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 Gene3D G3DSA:1.10.40.30 363 439 1.2E-140 T 12-10-2018 AFR_00705 9a181a5c8d8bbcdd0e18a41a8099f0ea 473 Pfam PF00206 Lyase 49 301 1.6E-24 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_16705 d451b23a257a3a1150fbe6428f32679a 294 Pfam PF12006 Protein of unknown function (DUF3500) 54 291 1.0E-44 T 12-10-2018 IPR021889 Protein of unknown function DUF3500 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 Pfam PF03466 LysR substrate binding domain 118 283 5.0E-18 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.5E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.5E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.5E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 Gene3D G3DSA:3.40.190.10 159 262 8.7E-17 T 12-10-2018 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 Gene3D G3DSA:1.10.10.10 4 90 3.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 SUPERFAMILY SSF53850 118 284 6.7E-17 T 12-10-2018 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.7E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 Gene3D G3DSA:3.40.190.10 126 281 8.7E-17 T 12-10-2018 AFR_38760 c19b316a7ebf3db5d22b596fd76ef69d 286 SUPERFAMILY SSF46785 4 87 3.44E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_34625 84207aec40ccc05ee192de43bea798e4 428 Pfam PF07730 Histidine kinase 226 293 1.1E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_34625 84207aec40ccc05ee192de43bea798e4 428 SUPERFAMILY SSF55874 300 414 7.08E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34625 84207aec40ccc05ee192de43bea798e4 428 Pfam PF13796 Putative sensor 21 197 2.8E-18 T 12-10-2018 IPR025828 Putative sensor domain AFR_34625 84207aec40ccc05ee192de43bea798e4 428 Gene3D G3DSA:3.30.565.10 295 415 1.2E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 SMART SM00387 425 536 3.3E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 SUPERFAMILY SSF55781 23 159 7.2E-21 T 12-10-2018 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 Gene3D G3DSA:3.30.565.10 387 535 4.5E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 514 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 534 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 492 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 478 6.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 Pfam PF00512 His Kinase A (phospho-acceptor) domain 317 383 4.9E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 Gene3D G3DSA:3.30.450.20 164 292 5.6E-11 T 12-10-2018 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 SUPERFAMILY SSF55874 377 535 3.14E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 SMART SM00065 21 161 0.0055 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 Gene3D G3DSA:1.10.287.130 293 382 2.1E-12 T 12-10-2018 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 SUPERFAMILY SSF55785 168 294 1.06E-9 T 12-10-2018 IPR035965 PAS domain superfamily AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 SUPERFAMILY SSF47384 301 383 3.53E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 SMART SM00388 316 384 2.7E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 426 534 4.2E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24000 427440eacbdf0a5f55dc5a105dc7a6a6 536 Gene3D G3DSA:3.30.450.40 5 163 1.7E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_39965 9af01fb716e14fdbb4722452bb261774 283 Pfam PF02811 PHP domain 5 66 4.5E-6 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFR_39965 9af01fb716e14fdbb4722452bb261774 283 Gene3D G3DSA:3.20.20.140 4 251 2.9E-75 T 12-10-2018 AFR_39965 9af01fb716e14fdbb4722452bb261774 283 SUPERFAMILY SSF89550 3 264 2.09E-43 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_39965 9af01fb716e14fdbb4722452bb261774 283 SMART SM00481 4 68 4.1E-14 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFR_39965 9af01fb716e14fdbb4722452bb261774 283 Gene3D G3DSA:1.10.150.650 100 170 2.9E-75 T 12-10-2018 AFR_17580 ad545fa097e796e8ec8ea6edf74bd5e1 397 Gene3D G3DSA:3.30.1540.10 232 324 6.9E-133 T 12-10-2018 AFR_17580 ad545fa097e796e8ec8ea6edf74bd5e1 397 Pfam PF02515 CoA-transferase family III 5 373 3.0E-127 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 AFR_17580 ad545fa097e796e8ec8ea6edf74bd5e1 397 Gene3D G3DSA:3.40.50.10540 4 391 6.9E-133 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily AFR_17580 ad545fa097e796e8ec8ea6edf74bd5e1 397 SUPERFAMILY SSF89796 3 397 1.14E-130 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily AFR_09120 3e908b5f5c58f0ec85417a7f8dfb9cd4 366 Pfam PF00589 Phage integrase family 148 336 4.3E-25 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_09120 3e908b5f5c58f0ec85417a7f8dfb9cd4 366 Gene3D G3DSA:1.10.150.130 41 144 1.1E-18 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_09120 3e908b5f5c58f0ec85417a7f8dfb9cd4 366 SUPERFAMILY SSF56349 42 342 1.59E-57 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_09120 3e908b5f5c58f0ec85417a7f8dfb9cd4 366 Gene3D G3DSA:1.10.443.10 145 348 9.2E-47 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_31995 864343778653060649951afe960e6caa 124 SUPERFAMILY SSF51182 3 108 4.34E-18 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_31995 864343778653060649951afe960e6caa 124 Gene3D G3DSA:2.60.120.10 1 121 4.6E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_31995 864343778653060649951afe960e6caa 124 Pfam PF07883 Cupin domain 37 100 2.0E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_29360 eed9c6e00158c11affa67962d78efe2a 189 Gene3D G3DSA:1.10.357.10 51 185 2.2E-25 T 12-10-2018 AFR_29360 eed9c6e00158c11affa67962d78efe2a 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 1.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29360 eed9c6e00158c11affa67962d78efe2a 189 Gene3D G3DSA:1.10.10.60 2 48 3.4E-17 T 12-10-2018 AFR_29360 eed9c6e00158c11affa67962d78efe2a 189 SUPERFAMILY SSF46689 6 69 9.48E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29360 eed9c6e00158c11affa67962d78efe2a 189 SUPERFAMILY SSF48498 77 180 1.04E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_29360 eed9c6e00158c11affa67962d78efe2a 189 Pfam PF13305 WHG domain 84 160 2.2E-7 T 12-10-2018 IPR025996 WHG domain AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 SUPERFAMILY SSF48264 7 387 9.69E-87 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 141 156 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 184 206 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 124 140 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 282 309 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 340 351 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 80 91 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 331 340 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 310 325 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 PRINTS PR00359 B-class P450 signature 265 276 2.4E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 Pfam PF00067 Cytochrome P450 188 358 3.4E-24 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_16680 b355665f490e9e4245fa6a1e21cd5f87 390 Gene3D G3DSA:1.10.630.10 1 390 3.2E-119 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 SMART SM00089 478 561 8.1E-22 T 12-10-2018 IPR022409 PKD/Chitinase domain AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 SUPERFAMILY SSF50370 802 924 9.99E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Gene3D G3DSA:2.120.10.30 8 471 1.8E-69 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 SMART SM00606 660 793 5.0E-35 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Pfam PF00652 Ricin-type beta-trefoil lectin domain 801 922 4.3E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Pfam PF00801 PKD domain 493 548 4.8E-11 T 12-10-2018 IPR000601 PKD domain AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Gene3D G3DSA:2.60.40.10 472 558 4.9E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Pfam PF03422 Carbohydrate binding module (family 6) 668 792 2.2E-30 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 SMART SM00458 798 925 1.9E-26 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 SUPERFAMILY SSF49299 474 561 6.15E-23 T 12-10-2018 IPR035986 PKD domain superfamily AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 SUPERFAMILY SSF50952 9 455 6.41E-26 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Gene3D G3DSA:2.80.10.50 793 924 8.1E-39 T 12-10-2018 AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 SUPERFAMILY SSF49785 663 791 2.98E-24 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Pfam PF07995 Glucose / Sorbosone dehydrogenase 36 317 1.9E-34 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_39015 229e54e0d658e86cde0a688a6e2a5286 925 Gene3D G3DSA:2.60.120.260 658 792 4.4E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_21415 485956d8de9893aaf4737ea5699ce768 250 Pfam PF01553 Acyltransferase 28 148 7.6E-20 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_21415 485956d8de9893aaf4737ea5699ce768 250 SMART SM00563 34 152 2.0E-25 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_21415 485956d8de9893aaf4737ea5699ce768 250 SUPERFAMILY SSF69593 13 208 9.29E-33 T 12-10-2018 AFR_28370 725bdd0b0826320f716bbacc27663bf8 88 SUPERFAMILY SSF52091 1 87 2.94E-16 T 12-10-2018 IPR036513 STAS domain superfamily AFR_28370 725bdd0b0826320f716bbacc27663bf8 88 Gene3D G3DSA:3.30.750.24 1 88 6.1E-18 T 12-10-2018 IPR036513 STAS domain superfamily AFR_28370 725bdd0b0826320f716bbacc27663bf8 88 Pfam PF13466 STAS domain 1 79 3.8E-10 T 12-10-2018 IPR002645 STAS domain AFR_14715 13e054974d4f0525fc6fef84098ef931 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 85 1.1E-4 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_14715 13e054974d4f0525fc6fef84098ef931 342 Pfam PF13602 Zinc-binding dehydrogenase 191 339 1.1E-21 T 12-10-2018 AFR_14715 13e054974d4f0525fc6fef84098ef931 342 SUPERFAMILY SSF51735 117 306 7.37E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14715 13e054974d4f0525fc6fef84098ef931 342 Gene3D G3DSA:3.90.180.10 16 335 8.0E-81 T 12-10-2018 AFR_14715 13e054974d4f0525fc6fef84098ef931 342 Gene3D G3DSA:3.40.50.720 127 271 8.0E-81 T 12-10-2018 AFR_14715 13e054974d4f0525fc6fef84098ef931 342 SMART SM00829 17 339 1.4E-19 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_14715 13e054974d4f0525fc6fef84098ef931 342 SUPERFAMILY SSF50129 16 144 2.89E-28 T 12-10-2018 IPR011032 GroES-like superfamily AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 Gene3D G3DSA:1.10.357.10 12 241 1.1E-53 T 12-10-2018 AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 92 238 4.5E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 77 8.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 SUPERFAMILY SSF46689 27 87 3.69E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 SUPERFAMILY SSF48498 94 238 3.11E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 PRINTS PR00400 Tetracycline repressor protein signature 99 118 1.1E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 PRINTS PR00400 Tetracycline repressor protein signature 47 70 1.1E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_34380 4d72ff5f88bed9c9c6e31dc8363da2a0 242 PRINTS PR00400 Tetracycline repressor protein signature 155 174 1.1E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_04280 f3b9583ddbe004b496e1f44597cb0b15 307 Gene3D G3DSA:3.30.2010.10 74 164 2.7E-28 T 12-10-2018 AFR_04280 f3b9583ddbe004b496e1f44597cb0b15 307 Hamap MF_00188 Protease HtpX [htpX]. 19 294 28.284 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 AFR_04280 f3b9583ddbe004b496e1f44597cb0b15 307 Pfam PF01435 Peptidase family M48 80 294 2.5E-36 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 SUPERFAMILY SSF52467 186 365 8.09E-45 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 449 468 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 SUPERFAMILY SSF52518 394 605 5.18E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 SUPERFAMILY SSF52518 2 210 2.8E-31 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 Gene3D G3DSA:3.40.50.970 2 204 7.6E-31 T 12-10-2018 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 Gene3D G3DSA:3.40.50.1220 211 383 1.9E-40 T 12-10-2018 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 Gene3D G3DSA:3.40.50.970 391 584 5.4E-43 T 12-10-2018 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 413 571 4.9E-37 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 197 5.6E-34 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 354 3.8E-36 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFR_20700 cb959aa8b21a00820c7e6c2eb5268d5e 617 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 2 614 6.0E-277 T 12-10-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 AFR_24980 37c82ed4ea01f0b0f285b7004d262418 276 Gene3D G3DSA:3.40.630.30 51 213 6.4E-9 T 12-10-2018 AFR_24980 37c82ed4ea01f0b0f285b7004d262418 276 SUPERFAMILY SSF55729 52 201 8.05E-6 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_15635 26ccba606eebb8c686561a979ff6ee5b 212 SUPERFAMILY SSF53335 42 170 7.93E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_15635 26ccba606eebb8c686561a979ff6ee5b 212 Pfam PF13489 Methyltransferase domain 44 142 8.4E-12 T 12-10-2018 AFR_15635 26ccba606eebb8c686561a979ff6ee5b 212 Gene3D G3DSA:3.40.50.150 19 182 2.4E-20 T 12-10-2018 AFR_30920 6e9a8501071c31e30038d7d5f15addc6 210 PIRSF PIRSF009467 1 210 1.2E-43 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 AFR_30920 6e9a8501071c31e30038d7d5f15addc6 210 Gene3D G3DSA:1.10.4190.10 1 181 2.9E-27 T 12-10-2018 IPR038277 UreF domain superfamily AFR_30920 6e9a8501071c31e30038d7d5f15addc6 210 Pfam PF01730 UreF 30 163 5.0E-23 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 AFR_30920 6e9a8501071c31e30038d7d5f15addc6 210 Hamap MF_01385 Urease accessory protein UreF [ureF]. 1 210 17.554 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 AFR_20730 cbd89788ad865a3d55f5319ed34e5141 338 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 1 334 48.31 T 12-10-2018 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 AFR_20730 cbd89788ad865a3d55f5319ed34e5141 338 Gene3D G3DSA:3.30.360.10 142 263 2.6E-104 T 12-10-2018 AFR_20730 cbd89788ad865a3d55f5319ed34e5141 338 Gene3D G3DSA:3.40.50.720 3 312 2.6E-104 T 12-10-2018 AFR_20730 cbd89788ad865a3d55f5319ed34e5141 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 123 4.6E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_20730 cbd89788ad865a3d55f5319ed34e5141 338 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 164 235 1.7E-4 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_20730 cbd89788ad865a3d55f5319ed34e5141 338 SUPERFAMILY SSF51735 2 152 2.03E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_20730 cbd89788ad865a3d55f5319ed34e5141 338 SUPERFAMILY SSF55347 130 281 3.6E-19 T 12-10-2018 AFR_24485 a630675abc4354147b001d011ec45ed0 226 Pfam PF07987 Domain of unkown function (DUF1775) 92 153 1.0E-11 T 12-10-2018 IPR012533 YcnI-like AFR_24485 a630675abc4354147b001d011ec45ed0 226 Gene3D G3DSA:2.60.40.2230 22 165 1.2E-20 T 12-10-2018 IPR038507 YcnI-like superfamily AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 TIGRFAM TIGR00492 alr: alanine racemase 6 370 1.0E-87 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 Pfam PF00842 Alanine racemase, C-terminal domain 243 370 1.8E-40 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 Pfam PF01168 Alanine racemase, N-terminal domain 10 231 7.6E-63 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 SUPERFAMILY SSF51419 10 244 1.05E-57 T 12-10-2018 IPR029066 PLP-binding barrel AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 161 172 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 259 274 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 297 314 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 276 291 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 27 43 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 204 231 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 352 365 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 63 81 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 PRINTS PR00992 Alanine racemase signature 124 136 8.4E-62 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 Gene3D G3DSA:3.20.20.10 12 226 9.5E-125 T 12-10-2018 IPR029066 PLP-binding barrel AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 SMART SM01005 243 371 1.3E-61 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 Hamap MF_01201 Alanine racemase. 3 371 31.88 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 SUPERFAMILY SSF50621 236 371 9.07E-45 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_04835 c07a8fd4f9bf63fe1a5f2ceb538ba4ca 521 Gene3D G3DSA:2.40.37.10 10 370 9.5E-125 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_40750 e1a98b2e9698ea3788afc5988fe8f8ba 287 SUPERFAMILY SSF55729 9 285 1.09E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40750 e1a98b2e9698ea3788afc5988fe8f8ba 287 Gene3D G3DSA:3.40.630.30 1 287 1.2E-94 T 12-10-2018 AFR_40750 e1a98b2e9698ea3788afc5988fe8f8ba 287 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 7 285 2.1E-100 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 AFR_40750 e1a98b2e9698ea3788afc5988fe8f8ba 287 Pfam PF00583 Acetyltransferase (GNAT) family 171 276 1.8E-11 T 12-10-2018 IPR000182 GNAT domain AFR_40750 e1a98b2e9698ea3788afc5988fe8f8ba 287 PIRSF PIRSF021524 1 287 9.8E-107 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 AFR_40750 e1a98b2e9698ea3788afc5988fe8f8ba 287 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 4 287 36.665 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 AFR_15315 ca5d8b4df7862a77f1d151f91113eb83 275 Gene3D G3DSA:3.40.50.2300 22 256 8.4E-56 T 12-10-2018 AFR_15315 ca5d8b4df7862a77f1d151f91113eb83 275 Gene3D G3DSA:3.40.50.2300 111 235 8.4E-56 T 12-10-2018 AFR_15315 ca5d8b4df7862a77f1d151f91113eb83 275 Pfam PF13377 Periplasmic binding protein-like domain 119 274 7.7E-31 T 12-10-2018 AFR_15315 ca5d8b4df7862a77f1d151f91113eb83 275 SUPERFAMILY SSF53822 21 257 1.65E-50 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_38965 a0671d1d8a114d70b4404b2a0c7bb046 241 SUPERFAMILY SSF140959 9 233 2.22E-56 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFR_38965 a0671d1d8a114d70b4404b2a0c7bb046 241 Gene3D G3DSA:1.20.58.480 8 237 1.7E-58 T 12-10-2018 AFR_38965 a0671d1d8a114d70b4404b2a0c7bb046 241 Pfam PF03301 Tryptophan 2,3-dioxygenase 8 128 5.1E-24 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFR_30590 3829d92d62f34fe59e7c380d34fad9c2 200 SUPERFAMILY SSF52540 7 190 3.12E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30590 3829d92d62f34fe59e7c380d34fad9c2 200 Gene3D G3DSA:3.40.50.300 13 183 2.0E-63 T 12-10-2018 AFR_30590 3829d92d62f34fe59e7c380d34fad9c2 200 Gene3D G3DSA:3.30.63.10 40 99 2.0E-63 T 12-10-2018 AFR_30590 3829d92d62f34fe59e7c380d34fad9c2 200 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 10 184 5.1E-68 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFR_30590 3829d92d62f34fe59e7c380d34fad9c2 200 SMART SM00072 8 190 2.0E-59 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFR_30590 3829d92d62f34fe59e7c380d34fad9c2 200 Hamap MF_00328 Guanylate kinase [gmk]. 7 190 34.116 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFR_30590 3829d92d62f34fe59e7c380d34fad9c2 200 Pfam PF00625 Guanylate kinase 9 184 1.7E-46 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFR_35880 b61c03608090da413014b7b54a9d7b7a 412 Pfam PF13416 Bacterial extracellular solute-binding protein 61 356 7.8E-39 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_35880 b61c03608090da413014b7b54a9d7b7a 412 SUPERFAMILY SSF53850 43 406 6.21E-67 T 12-10-2018 AFR_35880 b61c03608090da413014b7b54a9d7b7a 412 Gene3D G3DSA:3.40.190.10 28 410 2.2E-69 T 12-10-2018 AFR_21830 927ce123d4c60cc705e317641dbbd00f 63 SUPERFAMILY SSF69047 5 62 4.32E-10 T 12-10-2018 IPR036629 YjbJ superfamily AFR_21830 927ce123d4c60cc705e317641dbbd00f 63 Pfam PF05532 CsbD-like 5 57 5.9E-16 T 12-10-2018 IPR008462 CsbD-like domain AFR_21830 927ce123d4c60cc705e317641dbbd00f 63 Gene3D G3DSA:1.10.1470.10 4 63 1.0E-7 T 12-10-2018 IPR036629 YjbJ superfamily AFR_36760 ae083c63a3990ac91891a9ab8da7f9fc 299 Pfam PF00892 EamA-like transporter family 134 263 1.4E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_36760 ae083c63a3990ac91891a9ab8da7f9fc 299 SUPERFAMILY SSF103481 31 124 3.66E-6 T 12-10-2018 AFR_36760 ae083c63a3990ac91891a9ab8da7f9fc 299 SUPERFAMILY SSF103481 171 268 6.54E-9 T 12-10-2018 AFR_12315 2f66f11e46ebc10cf3e042a0bad0afc7 85 SUPERFAMILY SSF53474 2 73 5.2E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12315 2f66f11e46ebc10cf3e042a0bad0afc7 85 Gene3D G3DSA:3.40.50.1820 1 80 1.8E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33670 97debda4db2e125c98518bd02eb6b4e5 311 SUPERFAMILY SSF56112 9 280 5.51E-15 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_33670 97debda4db2e125c98518bd02eb6b4e5 311 Gene3D G3DSA:3.90.1200.10 136 290 5.9E-6 T 12-10-2018 AFR_09900 ecd0a2e748c31f16a5bc863c428abb7b 234 Pfam PF13489 Methyltransferase domain 10 183 1.6E-16 T 12-10-2018 AFR_09900 ecd0a2e748c31f16a5bc863c428abb7b 234 Gene3D G3DSA:3.40.50.150 1 234 6.2E-52 T 12-10-2018 AFR_09900 ecd0a2e748c31f16a5bc863c428abb7b 234 SUPERFAMILY SSF53335 12 191 2.26E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_36270 745c2983d30305f5d46b79ad29beb745 305 Pfam PF00589 Phage integrase family 123 290 1.3E-44 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_36270 745c2983d30305f5d46b79ad29beb745 305 SUPERFAMILY SSF56349 136 303 5.3E-51 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_36270 745c2983d30305f5d46b79ad29beb745 305 Gene3D G3DSA:1.10.150.130 14 109 8.2E-13 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_36270 745c2983d30305f5d46b79ad29beb745 305 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 16 305 53.395 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD AFR_36270 745c2983d30305f5d46b79ad29beb745 305 Gene3D G3DSA:1.10.443.10 123 299 7.1E-58 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_36270 745c2983d30305f5d46b79ad29beb745 305 SUPERFAMILY SSF47823 17 106 3.34E-8 T 12-10-2018 AFR_36270 745c2983d30305f5d46b79ad29beb745 305 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 19 100 6.0E-13 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 Pfam PF00005 ABC transporter 357 506 3.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 Gene3D G3DSA:3.40.50.300 334 589 1.3E-77 T 12-10-2018 AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 SUPERFAMILY SSF52540 339 574 2.77E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 SMART SM00382 366 552 3.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 Pfam PF00664 ABC transporter transmembrane region 22 295 2.6E-35 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 Gene3D G3DSA:1.20.1560.10 4 323 7.6E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_10245 3dbcd63c957a1de2512e19e2718ac18b 590 SUPERFAMILY SSF90123 11 321 1.27E-56 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_15905 551ba4eceae040f8e309906c7d170bd8 385 Gene3D G3DSA:3.90.1150.10 261 385 8.0E-28 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_15905 551ba4eceae040f8e309906c7d170bd8 385 PIRSF PIRSF000390 7 385 1.1E-105 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_15905 551ba4eceae040f8e309906c7d170bd8 385 Gene3D G3DSA:3.40.640.10 3 260 3.7E-88 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_15905 551ba4eceae040f8e309906c7d170bd8 385 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 379 5.7E-109 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_15905 551ba4eceae040f8e309906c7d170bd8 385 SUPERFAMILY SSF53383 11 382 8.06E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_08190 d7c1a7a9f1deb4ef632ded082c7ee43d 269 Pfam PF01061 ABC-2 type transporter 22 232 4.3E-17 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_08190 d7c1a7a9f1deb4ef632ded082c7ee43d 269 PIRSF PIRSF006648 6 267 9.8E-26 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08190 d7c1a7a9f1deb4ef632ded082c7ee43d 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 155 179 6.6E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08190 d7c1a7a9f1deb4ef632ded082c7ee43d 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 211 230 6.6E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08190 d7c1a7a9f1deb4ef632ded082c7ee43d 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 38 59 6.6E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08190 d7c1a7a9f1deb4ef632ded082c7ee43d 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 118 143 6.6E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08190 d7c1a7a9f1deb4ef632ded082c7ee43d 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 191 210 6.6E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_32300 04b2d004b5f6178482facf566b5380dd 175 SUPERFAMILY SSF46689 2 57 9.23E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_32300 04b2d004b5f6178482facf566b5380dd 175 SUPERFAMILY SSF48498 68 174 9.79E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_32300 04b2d004b5f6178482facf566b5380dd 175 Gene3D G3DSA:1.10.357.10 1 172 5.6E-25 T 12-10-2018 AFR_32300 04b2d004b5f6178482facf566b5380dd 175 Pfam PF00440 Bacterial regulatory proteins, tetR family 3 43 1.5E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_40375 fee5cc98ceb15729abafe7b1fb933d1e 83 Pfam PF02599 Global regulator protein family 1 53 1.4E-24 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFR_40375 fee5cc98ceb15729abafe7b1fb933d1e 83 Gene3D G3DSA:3.30.70.1680 1 61 2.5E-26 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 AFR_40375 fee5cc98ceb15729abafe7b1fb933d1e 83 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 46 4.0E-13 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFR_40375 fee5cc98ceb15729abafe7b1fb933d1e 83 SUPERFAMILY SSF117130 1 54 4.45E-19 T 12-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 AFR_40375 fee5cc98ceb15729abafe7b1fb933d1e 83 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 64 1.0E-23 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFR_40375 fee5cc98ceb15729abafe7b1fb933d1e 83 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 69 17.595 T 12-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 PRINTS PR00050 Cold shock protein signature 25 34 1.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 PRINTS PR00050 Cold shock protein signature 40 58 1.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 12-10-2018 IPR019844 Cold-shock conserved site AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 SMART SM00357 3 67 2.4E-31 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 PIRSF PIRSF002599 1 67 1.2E-26 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 Gene3D G3DSA:2.40.50.140 1 65 2.1E-30 T 12-10-2018 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.1E-31 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_31215 17a5b0a996f48d9506b9145aec98fac7 67 SUPERFAMILY SSF50249 1 66 1.13E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 Pfam PF02824 TGS domain 399 452 8.9E-15 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 SMART SM00954 242 351 1.7E-34 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 Gene3D G3DSA:1.10.3210.10 12 199 4.8E-65 T 12-10-2018 AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 SUPERFAMILY SSF81301 211 371 1.63E-34 T 12-10-2018 AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 SUPERFAMILY SSF109604 16 198 3.14E-59 T 12-10-2018 AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 SUPERFAMILY SSF81271 398 452 3.05E-11 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 Pfam PF13328 HD domain 38 183 1.2E-39 T 12-10-2018 IPR003607 HD/PDEase domain AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 Gene3D G3DSA:3.30.460.10 202 330 7.1E-30 T 12-10-2018 AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 SMART SM00471 51 161 2.8E-13 T 12-10-2018 IPR003607 HD/PDEase domain AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 Gene3D G3DSA:3.10.20.30 387 459 1.2E-18 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_09465 64785a0b04d803f94a75ed47b37418a4 569 Pfam PF04607 Region found in RelA / SpoT proteins 269 349 3.5E-18 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 AFR_06880 4999a5de6e7a198d268e8d43f2c2a66e 323 Pfam PF00005 ABC transporter 18 160 3.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_06880 4999a5de6e7a198d268e8d43f2c2a66e 323 SUPERFAMILY SSF52540 2 222 8.3E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06880 4999a5de6e7a198d268e8d43f2c2a66e 323 Pfam PF13732 Domain of unknown function (DUF4162) 217 299 1.3E-7 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 AFR_06880 4999a5de6e7a198d268e8d43f2c2a66e 323 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_06880 4999a5de6e7a198d268e8d43f2c2a66e 323 Gene3D G3DSA:3.40.50.300 1 231 5.3E-66 T 12-10-2018 AFR_06880 4999a5de6e7a198d268e8d43f2c2a66e 323 SMART SM00382 26 210 1.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10480 0162bafa5e531e1b73da86002a72973e 109 SUPERFAMILY SSF54909 1 99 8.39E-23 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_10480 0162bafa5e531e1b73da86002a72973e 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 4.1E-13 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_10480 0162bafa5e531e1b73da86002a72973e 109 Gene3D G3DSA:3.30.70.100 1 96 3.5E-32 T 12-10-2018 AFR_27395 243950d3734a65faf8717cca143aa871 214 Gene3D G3DSA:3.40.50.150 1 193 8.0E-46 T 12-10-2018 AFR_27395 243950d3734a65faf8717cca143aa871 214 SUPERFAMILY SSF53335 2 204 1.4E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_27395 243950d3734a65faf8717cca143aa871 214 Pfam PF13649 Methyltransferase domain 41 131 1.5E-19 T 12-10-2018 AFR_12270 4463d0c14305fee8ce945721190e1952 550 SUPERFAMILY SSF53474 115 526 2.41E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12270 4463d0c14305fee8ce945721190e1952 550 Pfam PF08386 TAP-like protein 456 549 7.7E-22 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal AFR_12270 4463d0c14305fee8ce945721190e1952 550 Pfam PF00561 alpha/beta hydrolase fold 119 304 1.4E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01450 4ec38bac5e6bbe25350893dff02ec45d 614 Pfam PF00270 DEAD/DEAH box helicase 86 254 1.1E-42 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_01450 4ec38bac5e6bbe25350893dff02ec45d 614 Pfam PF00271 Helicase conserved C-terminal domain 298 396 2.0E-24 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_01450 4ec38bac5e6bbe25350893dff02ec45d 614 Gene3D G3DSA:3.40.50.300 30 268 1.1E-67 T 12-10-2018 AFR_01450 4ec38bac5e6bbe25350893dff02ec45d 614 SUPERFAMILY SSF52540 134 410 5.08E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01450 4ec38bac5e6bbe25350893dff02ec45d 614 Gene3D G3DSA:3.40.50.300 289 440 1.5E-42 T 12-10-2018 AFR_01450 4ec38bac5e6bbe25350893dff02ec45d 614 SMART SM00487 80 281 9.4E-51 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_01450 4ec38bac5e6bbe25350893dff02ec45d 614 SMART SM00490 315 396 6.6E-30 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_03855 adb8aa5551893f4ce770effc68dd7ba9 314 Gene3D G3DSA:3.90.180.10 10 305 1.2E-52 T 12-10-2018 AFR_03855 adb8aa5551893f4ce770effc68dd7ba9 314 SUPERFAMILY SSF50129 1 139 3.9E-21 T 12-10-2018 IPR011032 GroES-like superfamily AFR_03855 adb8aa5551893f4ce770effc68dd7ba9 314 Gene3D G3DSA:3.40.50.720 115 288 1.2E-52 T 12-10-2018 AFR_03855 adb8aa5551893f4ce770effc68dd7ba9 314 SMART SM00829 10 312 5.7E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_03855 adb8aa5551893f4ce770effc68dd7ba9 314 SUPERFAMILY SSF51735 109 285 4.86E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03855 adb8aa5551893f4ce770effc68dd7ba9 314 Pfam PF00107 Zinc-binding dehydrogenase 147 262 6.8E-16 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_10310 0950a4bf0552b2b745f107910dedca62 413 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 398 49.851 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_10310 0950a4bf0552b2b745f107910dedca62 413 Gene3D G3DSA:3.40.50.1100 58 391 4.8E-174 T 12-10-2018 AFR_10310 0950a4bf0552b2b745f107910dedca62 413 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 385 4.1E-45 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_10310 0950a4bf0552b2b745f107910dedca62 413 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 394 2.4E-177 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_10310 0950a4bf0552b2b745f107910dedca62 413 SUPERFAMILY SSF53686 7 395 7.99E-141 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_10310 0950a4bf0552b2b745f107910dedca62 413 Gene3D G3DSA:3.40.50.1100 14 209 4.8E-174 T 12-10-2018 AFR_10310 0950a4bf0552b2b745f107910dedca62 413 PIRSF PIRSF001413 1 401 2.7E-151 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 Gene3D G3DSA:1.10.1660.10 1 124 3.7E-30 T 12-10-2018 AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 Pfam PF13411 MerR HTH family regulatory protein 2 69 2.0E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 3.1E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 3.1E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 3.1E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 SUPERFAMILY SSF46955 2 120 2.93E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_20005 4b5faf7dae72ee14981a7b768cc46d0d 127 SMART SM00422 2 71 5.6E-34 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_20595 a2e6ed76a8c44c01732323c1f9bcd266 259 SUPERFAMILY SSF54637 120 256 2.1E-9 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_20595 a2e6ed76a8c44c01732323c1f9bcd266 259 Gene3D G3DSA:3.10.129.90 8 255 7.5E-17 T 12-10-2018 AFR_20595 a2e6ed76a8c44c01732323c1f9bcd266 259 Pfam PF13622 Thioesterase-like superfamily 23 254 7.6E-31 T 12-10-2018 AFR_33050 88bc1d98878d7d9bc92d65d0cccdca52 273 Pfam PF08241 Methyltransferase domain 58 153 5.9E-22 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_33050 88bc1d98878d7d9bc92d65d0cccdca52 273 SUPERFAMILY SSF53335 31 247 8.44E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_33050 88bc1d98878d7d9bc92d65d0cccdca52 273 Gene3D G3DSA:3.40.50.150 23 223 2.2E-33 T 12-10-2018 AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 3.2E-4 T 12-10-2018 AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 Pfam PF00106 short chain dehydrogenase 8 187 1.7E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 SUPERFAMILY SSF51735 1 238 9.46E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 4.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 4.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 4.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38585 72f575a0eca2c6d3178848df887eafd3 241 Gene3D G3DSA:3.40.50.720 1 235 4.4E-38 T 12-10-2018 AFR_09460 df10f0efa29e56f0eb4e20218a0af24b 161 SUPERFAMILY SSF55811 12 145 5.55E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_09460 df10f0efa29e56f0eb4e20218a0af24b 161 ProSitePatterns PS00893 Nudix box signature. 63 84 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_09460 df10f0efa29e56f0eb4e20218a0af24b 161 Pfam PF00293 NUDIX domain 31 148 2.2E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_09460 df10f0efa29e56f0eb4e20218a0af24b 161 Gene3D G3DSA:3.90.79.10 18 152 1.2E-21 T 12-10-2018 AFR_41135 c73899d8f45521a8c1beaeb15a5151c4 555 PIRSF PIRSF001394 33 551 1.5E-213 T 12-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 AFR_41135 c73899d8f45521a8c1beaeb15a5151c4 555 Gene3D G3DSA:3.20.130.10 357 543 3.4E-57 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AFR_41135 c73899d8f45521a8c1beaeb15a5151c4 555 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 91 333 2.0E-30 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFR_41135 c73899d8f45521a8c1beaeb15a5151c4 555 Pfam PF05683 Fumarase C-terminus 338 544 1.6E-91 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFR_41135 c73899d8f45521a8c1beaeb15a5151c4 555 SUPERFAMILY SSF117457 368 542 3.01E-60 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AFR_41135 c73899d8f45521a8c1beaeb15a5151c4 555 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 380 544 2.6E-55 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFR_41135 c73899d8f45521a8c1beaeb15a5151c4 555 Pfam PF05681 Fumarate hydratase (Fumerase) 53 332 9.9E-84 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFR_10380 3f86afa2d5e5b0bcda1f81f273e1482d 232 PRINTS PR00379 Intein signature 152 164 3.9E-5 T 12-10-2018 IPR006142 Intein GO:0016539 AFR_10380 3f86afa2d5e5b0bcda1f81f273e1482d 232 PRINTS PR00379 Intein signature 52 64 3.9E-5 T 12-10-2018 IPR006142 Intein GO:0016539 AFR_10380 3f86afa2d5e5b0bcda1f81f273e1482d 232 Gene3D G3DSA:3.10.28.10 50 216 1.2E-10 T 12-10-2018 IPR027434 Homing endonuclease AFR_13145 56204ecea2bdbcb02ff64f0b9fee609c 228 SUPERFAMILY SSF52499 15 201 1.7E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_13145 56204ecea2bdbcb02ff64f0b9fee609c 228 Gene3D G3DSA:3.40.50.850 17 227 9.9E-45 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_13145 56204ecea2bdbcb02ff64f0b9fee609c 228 Pfam PF00857 Isochorismatase family 23 197 1.5E-28 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 Gene3D G3DSA:3.50.50.60 9 336 8.5E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 SUPERFAMILY SSF51905 7 363 5.19E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 Pfam PF01494 FAD binding domain 7 334 1.2E-73 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 7.3E-41 T 12-10-2018 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 7.3E-41 T 12-10-2018 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 7.3E-41 T 12-10-2018 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 7.3E-41 T 12-10-2018 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 7.3E-41 T 12-10-2018 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 7.3E-41 T 12-10-2018 AFR_07310 f129eb8ded06989ec8c08e5be2c83e71 485 Gene3D G3DSA:3.30.70.2450 182 259 8.5E-93 T 12-10-2018 AFR_27685 3400670ef1339f6c9c4d2804c48957b4 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_27685 3400670ef1339f6c9c4d2804c48957b4 226 SMART SM00382 30 217 3.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_27685 3400670ef1339f6c9c4d2804c48957b4 226 Pfam PF00005 ABC transporter 21 169 5.6E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_27685 3400670ef1339f6c9c4d2804c48957b4 226 SUPERFAMILY SSF52540 5 221 1.56E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27685 3400670ef1339f6c9c4d2804c48957b4 226 Gene3D G3DSA:3.40.50.300 1 222 4.4E-67 T 12-10-2018 AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 SUPERFAMILY SSF46785 5 144 4.02E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 Pfam PF01047 MarR family 37 94 2.9E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 Gene3D G3DSA:1.10.10.10 2 142 3.0E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 69 103 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 2.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12920 16a2caf8b680e86e20a66829c23810a8 160 SMART SM00347 30 130 2.3E-18 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_13685 49659ca3550195884570305e8b614af2 339 SUPERFAMILY SSF46689 287 338 4.66E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13685 49659ca3550195884570305e8b614af2 339 Pfam PF14525 AraC-binding-like domain 34 214 1.3E-29 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_13685 49659ca3550195884570305e8b614af2 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 321 337 7.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_13685 49659ca3550195884570305e8b614af2 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 306 321 7.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_13685 49659ca3550195884570305e8b614af2 339 SMART SM00342 251 337 3.1E-32 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_13685 49659ca3550195884570305e8b614af2 339 SUPERFAMILY SSF46689 235 285 1.61E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13685 49659ca3550195884570305e8b614af2 339 Pfam PF12833 Helix-turn-helix domain 257 338 2.2E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_13685 49659ca3550195884570305e8b614af2 339 Gene3D G3DSA:1.10.10.60 235 339 1.9E-36 T 12-10-2018 AFR_13685 49659ca3550195884570305e8b614af2 339 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 288 333 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_17370 4574a2eee14e4d55956828411cc5451a 482 Pfam PF00990 Diguanylate cyclase, GGDEF domain 326 472 5.1E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_17370 4574a2eee14e4d55956828411cc5451a 482 SMART SM00267 315 476 3.6E-49 T 12-10-2018 IPR000160 GGDEF domain AFR_17370 4574a2eee14e4d55956828411cc5451a 482 SUPERFAMILY SSF55073 331 476 1.8E-42 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_17370 4574a2eee14e4d55956828411cc5451a 482 Gene3D G3DSA:3.30.70.270 312 476 1.1E-49 T 12-10-2018 AFR_17370 4574a2eee14e4d55956828411cc5451a 482 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 324 475 6.6E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_01190 b32d08d3b14975245e6a2a856e963838 255 Pfam PF13490 Putative zinc-finger 3 37 1.5E-12 T 12-10-2018 IPR027383 Putative zinc-finger AFR_01190 b32d08d3b14975245e6a2a856e963838 255 Gene3D G3DSA:1.10.10.1320 4 90 4.9E-6 T 12-10-2018 AFR_34075 40e507ddc8d6fb924aa9598c34402808 507 SUPERFAMILY SSF52743 62 389 4.45E-60 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_34075 40e507ddc8d6fb924aa9598c34402808 507 Gene3D G3DSA:3.40.50.200 48 369 1.7E-64 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_34075 40e507ddc8d6fb924aa9598c34402808 507 Pfam PF00082 Subtilase family 75 372 1.8E-34 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_34075 40e507ddc8d6fb924aa9598c34402808 507 PRINTS PR00723 Subtilisin serine protease family (S8) signature 75 94 5.7E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34075 40e507ddc8d6fb924aa9598c34402808 507 PRINTS PR00723 Subtilisin serine protease family (S8) signature 117 130 5.7E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_34075 40e507ddc8d6fb924aa9598c34402808 507 PRINTS PR00723 Subtilisin serine protease family (S8) signature 308 324 5.7E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SUPERFAMILY SSF55874 713 821 1.81E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SMART SM00065 353 497 8.7E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SMART SM00065 35 180 3.8E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SMART SM00065 201 332 9.6E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Gene3D G3DSA:3.30.450.40 202 336 5.4E-12 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Gene3D G3DSA:3.30.450.40 565 649 1.1E-6 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Gene3D G3DSA:3.30.450.40 490 564 2.9E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Gene3D G3DSA:3.30.450.40 337 489 2.5E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SUPERFAMILY SSF55781 186 323 1.42E-12 T 12-10-2018 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SUPERFAMILY SSF55781 503 616 9.16E-11 T 12-10-2018 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Pfam PF01590 GAF domain 38 172 2.1E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Pfam PF01590 GAF domain 355 487 6.1E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Pfam PF01590 GAF domain 203 321 3.1E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Gene3D G3DSA:3.30.565.10 705 821 3.1E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Gene3D G3DSA:3.30.450.40 15 181 7.3E-18 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SUPERFAMILY SSF55781 38 174 5.02E-16 T 12-10-2018 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 Pfam PF07730 Histidine kinase 636 700 3.3E-7 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_28950 7cb9a7d0938822f243816c2b0aca6729 836 SUPERFAMILY SSF55781 355 500 1.09E-19 T 12-10-2018 AFR_03495 e98bf9774c6bc36a9c53ce0bac0df637 191 Pfam PF03358 NADPH-dependent FMN reductase 7 145 3.0E-35 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_03495 e98bf9774c6bc36a9c53ce0bac0df637 191 Gene3D G3DSA:3.40.50.360 3 190 5.2E-46 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_03495 e98bf9774c6bc36a9c53ce0bac0df637 191 SUPERFAMILY SSF52218 5 170 1.09E-37 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 SUPERFAMILY SSF46785 4 64 2.06E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 SUPERFAMILY SSF54909 66 142 1.17E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 Gene3D G3DSA:1.10.10.10 1 58 1.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 SMART SM00344 5 111 6.3E-31 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 Pfam PF01037 Lrp/AsnC ligand binding domain 71 142 8.6E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 Gene3D G3DSA:3.30.70.920 59 147 2.4E-19 T 12-10-2018 AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 1.7E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.8E-8 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.8E-8 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_16915 c050b717ad4af6710e0ff80fdd82843b 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.8E-8 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 23 128 1.6E-29 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 SUPERFAMILY SSF50129 5 170 5.93E-46 T 12-10-2018 IPR011032 GroES-like superfamily AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 Pfam PF00107 Zinc-binding dehydrogenase 172 298 9.4E-29 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 Gene3D G3DSA:3.90.180.10 11 323 4.9E-96 T 12-10-2018 AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 Gene3D G3DSA:3.40.50.720 148 283 4.9E-96 T 12-10-2018 AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 SMART SM00829 6 334 1.0E-5 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_34755 180fea43b33b87477f1bddd94df2f8b6 342 SUPERFAMILY SSF51735 138 303 5.64E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11035 b91c432633a5548c56bc18b0c0303cdd 398 Pfam PF07730 Histidine kinase 197 262 5.8E-20 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_11035 b91c432633a5548c56bc18b0c0303cdd 398 SUPERFAMILY SSF55874 280 394 7.19E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11035 b91c432633a5548c56bc18b0c0303cdd 398 Gene3D G3DSA:3.30.565.10 274 394 3.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 PIRSF PIRSF000447 1 408 8.5E-144 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 6 405 9.3E-152 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 SUPERFAMILY SSF53901 4 250 3.76E-64 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 246 6.6E-53 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 SMART SM00825 Beta-ketoacyl synthase 6 408 5.0E-13 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 Gene3D G3DSA:3.40.47.10 259 408 3.1E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 Gene3D G3DSA:3.40.47.10 1 254 5.9E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 SUPERFAMILY SSF53901 214 407 3.74E-65 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_08685 d296bfc658a3172687e2af1c1835ae0c 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 365 7.2E-33 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFR_38390 5168285bd7670f1ade61ea3763ae242a 326 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 68 138 3.6E-8 T 12-10-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 AFR_38390 5168285bd7670f1ade61ea3763ae242a 326 Pfam PF00293 NUDIX domain 190 287 1.7E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_38390 5168285bd7670f1ade61ea3763ae242a 326 ProSitePatterns PS00893 Nudix box signature. 214 235 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_38390 5168285bd7670f1ade61ea3763ae242a 326 Gene3D G3DSA:3.90.79.10 173 322 1.3E-30 T 12-10-2018 AFR_38390 5168285bd7670f1ade61ea3763ae242a 326 SUPERFAMILY SSF55811 124 295 2.17E-35 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_35055 6385a4b04990fa435b7d03b2ae871211 355 SUPERFAMILY SSF50249 202 339 4.03E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_35055 6385a4b04990fa435b7d03b2ae871211 355 SUPERFAMILY SSF56091 7 201 2.88E-43 T 12-10-2018 AFR_35055 6385a4b04990fa435b7d03b2ae871211 355 Gene3D G3DSA:3.30.470.30 8 201 1.9E-44 T 12-10-2018 AFR_35055 6385a4b04990fa435b7d03b2ae871211 355 Gene3D G3DSA:2.40.50.140 202 338 5.6E-29 T 12-10-2018 AFR_35055 6385a4b04990fa435b7d03b2ae871211 355 Pfam PF01068 ATP dependent DNA ligase domain 11 199 4.2E-38 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AFR_35055 6385a4b04990fa435b7d03b2ae871211 355 Pfam PF04679 ATP dependent DNA ligase C terminal region 219 330 1.5E-12 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AFR_21750 6f509a0b2be3fdfb732c24f2559195be 195 Gene3D G3DSA:1.10.10.10 1 87 1.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21750 6f509a0b2be3fdfb732c24f2559195be 195 Pfam PF12840 Helix-turn-helix domain 12 68 2.7E-12 T 12-10-2018 AFR_21750 6f509a0b2be3fdfb732c24f2559195be 195 SUPERFAMILY SSF46785 4 105 1.29E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24935 9b0400fb941a273eeaaf1cbbe27b8886 134 SMART SM00347 9 113 3.7E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_24935 9b0400fb941a273eeaaf1cbbe27b8886 134 Gene3D G3DSA:1.10.10.10 1 129 6.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24935 9b0400fb941a273eeaaf1cbbe27b8886 134 Pfam PF12802 MarR family 15 76 8.4E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_24935 9b0400fb941a273eeaaf1cbbe27b8886 134 SUPERFAMILY SSF46785 8 127 7.29E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41880 1dca2cac8f775a1707be127c1dd49ecc 235 Gene3D G3DSA:3.40.50.1580 2 235 1.1E-71 T 12-10-2018 AFR_41880 1dca2cac8f775a1707be127c1dd49ecc 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 233 1.3E-92 T 12-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 AFR_41880 1dca2cac8f775a1707be127c1dd49ecc 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 12-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFR_41880 1dca2cac8f775a1707be127c1dd49ecc 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 235 45.123 T 12-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 AFR_41880 1dca2cac8f775a1707be127c1dd49ecc 235 Pfam PF01048 Phosphorylase superfamily 15 216 1.5E-40 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFR_41880 1dca2cac8f775a1707be127c1dd49ecc 235 SUPERFAMILY SSF53167 2 234 1.05E-82 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFR_07775 441b8bb16d7a0b05c415adae9bce5055 324 Gene3D G3DSA:3.40.50.300 1 121 4.6E-10 T 12-10-2018 AFR_07775 441b8bb16d7a0b05c415adae9bce5055 324 SUPERFAMILY SSF52540 6 185 1.96E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07775 441b8bb16d7a0b05c415adae9bce5055 324 Gene3D G3DSA:1.20.272.10 195 319 4.8E-17 T 12-10-2018 AFR_07775 441b8bb16d7a0b05c415adae9bce5055 324 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 8 313 2.3E-30 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 AFR_07775 441b8bb16d7a0b05c415adae9bce5055 324 SUPERFAMILY SSF48019 198 315 2.47E-13 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFR_07775 441b8bb16d7a0b05c415adae9bce5055 324 Pfam PF06144 DNA polymerase III, delta subunit 12 170 3.8E-7 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 SMART SM00345 29 88 9.4E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 4.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 4.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 SUPERFAMILY SSF46785 18 92 2.63E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 Pfam PF07702 UTRA domain 110 244 1.4E-35 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 88 1.5E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 Gene3D G3DSA:1.10.10.10 23 92 6.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 SUPERFAMILY SSF64288 76 250 2.67E-44 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 SMART SM00866 108 245 3.4E-35 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_20680 13d8819788de5d197c952f3daf82f0ce 253 Gene3D G3DSA:3.40.1410.10 93 252 1.2E-40 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_24235 7f2db74f0027f319768cde6ec212f0f5 329 Gene3D G3DSA:1.10.3720.10 99 323 4.4E-18 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24235 7f2db74f0027f319768cde6ec212f0f5 329 SUPERFAMILY SSF161098 106 310 3.92E-16 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24235 7f2db74f0027f319768cde6ec212f0f5 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 326 3.7E-33 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_38960 1ae5d0908a7b2d2ca3ca123fe1b2eda7 329 SUPERFAMILY SSF53448 9 219 1.03E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_38960 1ae5d0908a7b2d2ca3ca123fe1b2eda7 329 Pfam PF00535 Glycosyl transferase family 2 12 141 1.1E-28 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_38960 1ae5d0908a7b2d2ca3ca123fe1b2eda7 329 Gene3D G3DSA:3.90.550.10 6 221 4.3E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_04585 df4dce5ce104c26cbd54a1d810f99d7b 131 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 17 131 26.248 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04585 df4dce5ce104c26cbd54a1d810f99d7b 131 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 17 131 6.2E-46 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04585 df4dce5ce104c26cbd54a1d810f99d7b 131 SUPERFAMILY SSF53137 21 129 3.71E-44 T 12-10-2018 AFR_04585 df4dce5ce104c26cbd54a1d810f99d7b 131 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 22 131 1.7E-36 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04585 df4dce5ce104c26cbd54a1d810f99d7b 131 Gene3D G3DSA:3.30.420.100 17 131 7.0E-39 T 12-10-2018 AFR_05955 42201008d8eff7c2ddd5748953574c5a 147 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 30 4.2E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_05955 42201008d8eff7c2ddd5748953574c5a 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_05955 42201008d8eff7c2ddd5748953574c5a 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 2.3E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_16270 4ed2899678312b0acf1b82496511f02c 379 SUPERFAMILY SSF51905 6 368 2.99E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_16270 4ed2899678312b0acf1b82496511f02c 379 Gene3D G3DSA:3.50.50.60 1 371 2.8E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_16270 4ed2899678312b0acf1b82496511f02c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 1.4E-18 T 12-10-2018 AFR_16270 4ed2899678312b0acf1b82496511f02c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.4E-18 T 12-10-2018 AFR_16270 4ed2899678312b0acf1b82496511f02c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.4E-18 T 12-10-2018 AFR_16270 4ed2899678312b0acf1b82496511f02c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 1.4E-18 T 12-10-2018 AFR_16270 4ed2899678312b0acf1b82496511f02c 379 Pfam PF01494 FAD binding domain 6 346 1.2E-18 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_01660 1e8fbcfecbacae5ffe3661db801d4efb 223 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 1.6E-67 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01660 1e8fbcfecbacae5ffe3661db801d4efb 223 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 41.88 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01660 1e8fbcfecbacae5ffe3661db801d4efb 223 SUPERFAMILY SSF56770 9 151 4.45E-64 T 12-10-2018 AFR_01660 1e8fbcfecbacae5ffe3661db801d4efb 223 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01660 1e8fbcfecbacae5ffe3661db801d4efb 223 Gene3D G3DSA:3.40.50.12280 2 168 4.4E-72 T 12-10-2018 AFR_01660 1e8fbcfecbacae5ffe3661db801d4efb 223 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 1.3E-23 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_29615 ae61e95827e338d95d9032e5df059132 1464 Pfam PF08378 Nuclease-related domain 15 118 1.2E-14 T 12-10-2018 IPR011528 Nuclease-related domain, NERD AFR_29615 ae61e95827e338d95d9032e5df059132 1464 Pfam PF00069 Protein kinase domain 249 493 3.7E-12 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_29615 ae61e95827e338d95d9032e5df059132 1464 Pfam PF00069 Protein kinase domain 542 737 3.9E-19 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_29615 ae61e95827e338d95d9032e5df059132 1464 Gene3D G3DSA:1.10.510.10 258 511 5.8E-22 T 12-10-2018 AFR_29615 ae61e95827e338d95d9032e5df059132 1464 SMART SM00220 540 793 1.9E-11 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_29615 ae61e95827e338d95d9032e5df059132 1464 SUPERFAMILY SSF56112 257 499 2.08E-20 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_29615 ae61e95827e338d95d9032e5df059132 1464 Gene3D G3DSA:1.10.510.10 535 849 7.0E-27 T 12-10-2018 AFR_29615 ae61e95827e338d95d9032e5df059132 1464 SUPERFAMILY SSF56112 537 798 1.09E-28 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 Pfam PF00571 CBS domain 289 340 7.5E-5 T 12-10-2018 IPR000644 CBS domain AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 Pfam PF03471 Transporter associated domain 364 436 4.3E-24 T 12-10-2018 IPR005170 Transporter-associated domain AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 Gene3D G3DSA:3.10.580.10 203 348 1.3E-43 T 12-10-2018 AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 SUPERFAMILY SSF56176 363 443 5.45E-24 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 Gene3D G3DSA:3.30.465.10 366 438 8.6E-23 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 Pfam PF01595 Domain of unknown function DUF21 14 204 3.4E-38 T 12-10-2018 IPR002550 CNNM, transmembrane domain AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 SMART SM01091 361 439 2.4E-29 T 12-10-2018 IPR005170 Transporter-associated domain AFR_00335 4c92029caf97690fdd82f5270f3eda3c 444 SUPERFAMILY SSF54631 215 350 1.64E-26 T 12-10-2018 AFR_40430 abb640dc80636bbcc3417643ef4a0f5b 111 Pfam PF02049 Flagellar hook-basal body complex protein FliE 30 110 1.4E-21 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFR_40430 abb640dc80636bbcc3417643ef4a0f5b 111 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 30 110 1.1E-13 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFR_40430 abb640dc80636bbcc3417643ef4a0f5b 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 41 57 2.8E-6 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFR_40430 abb640dc80636bbcc3417643ef4a0f5b 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 96 109 2.8E-6 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFR_40430 abb640dc80636bbcc3417643ef4a0f5b 111 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 111 13.87 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFR_22420 01efe1501defc32a9d41457c5b44d308 298 Gene3D G3DSA:3.90.25.10 160 268 6.3E-66 T 12-10-2018 AFR_22420 01efe1501defc32a9d41457c5b44d308 298 Pfam PF05368 NmrA-like family 4 241 1.9E-45 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 AFR_22420 01efe1501defc32a9d41457c5b44d308 298 SUPERFAMILY SSF51735 4 274 3.45E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_22420 01efe1501defc32a9d41457c5b44d308 298 Gene3D G3DSA:3.40.50.720 4 220 6.3E-66 T 12-10-2018 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 404 1.1E-14 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 Pfam PF08245 Mur ligase middle domain 122 303 6.4E-22 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 SUPERFAMILY SSF51984 20 105 1.31E-23 T 12-10-2018 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 Pfam PF01225 Mur ligase family, catalytic domain 19 116 2.2E-19 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 Gene3D G3DSA:3.90.190.20 322 471 3.0E-37 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 SUPERFAMILY SSF53623 103 321 4.92E-60 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 SUPERFAMILY SSF53244 323 468 2.62E-36 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 Gene3D G3DSA:3.40.1190.10 106 321 7.2E-69 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 17 471 35.783 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 Gene3D G3DSA:3.40.50.720 19 105 4.0E-26 T 12-10-2018 AFR_10015 db817a8dfac7ce1ccd3fbaf04b7eeeca 472 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 20 465 7.8E-129 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_26525 177dc32c37b4be7e0ee7d0c2f329a78f 332 Pfam PF01066 CDP-alcohol phosphatidyltransferase 44 111 7.8E-11 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_26525 177dc32c37b4be7e0ee7d0c2f329a78f 332 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 89 111 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_26525 177dc32c37b4be7e0ee7d0c2f329a78f 332 Gene3D G3DSA:1.20.120.1760 14 183 3.7E-33 T 12-10-2018 AFR_24630 148a435be6ed1a49f1076624948fc592 216 SUPERFAMILY SSF46689 7 86 1.69E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_24630 148a435be6ed1a49f1076624948fc592 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 3.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_24630 148a435be6ed1a49f1076624948fc592 216 Gene3D G3DSA:1.10.357.10 12 216 9.4E-57 T 12-10-2018 AFR_24470 ae996cc5d9f78ca695689802c4cb44be 551 Pfam PF00890 FAD binding domain 4 533 1.1E-111 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_24470 ae996cc5d9f78ca695689802c4cb44be 551 Gene3D G3DSA:3.50.50.60 3 547 7.0E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_24470 ae996cc5d9f78ca695689802c4cb44be 551 Gene3D G3DSA:3.90.700.10 275 485 7.0E-59 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_24470 ae996cc5d9f78ca695689802c4cb44be 551 SUPERFAMILY SSF51905 2 549 6.0E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_24470 ae996cc5d9f78ca695689802c4cb44be 551 PIRSF PIRSF036654 1 551 3.8E-293 T 12-10-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 SUPERFAMILY SSF51735 1 225 8.12E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 2 224 3.5E-44 T 12-10-2018 AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 Gene3D G3DSA:3.40.50.720 1 227 1.7E-59 T 12-10-2018 AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 113 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 208 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 142 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 161 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23700 c00a7794297adbd9690fc8cbb17a6311 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 50 61 1.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 SUPERFAMILY SSF51735 5 247 6.03E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 247 4.3E-73 T 12-10-2018 AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36045 efd48f1f38ddd11cf117c5a824fc8beb 254 Gene3D G3DSA:3.40.50.720 2 254 1.1E-90 T 12-10-2018 AFR_35285 eb5b21f05fabc239a5441f49462c5eda 125 PIRSF PIRSF006910 1 124 1.9E-44 T 12-10-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted AFR_21095 5e957799a0f35893b1dd206f3d180b0c 154 Pfam PF02577 Bifunctional nuclease 6 128 2.0E-44 T 12-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 AFR_21095 5e957799a0f35893b1dd206f3d180b0c 154 Gene3D G3DSA:3.10.690.10 1 140 1.5E-47 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 AFR_21095 5e957799a0f35893b1dd206f3d180b0c 154 SUPERFAMILY SSF103256 2 136 9.55E-45 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 Gene3D G3DSA:3.40.50.300 247 508 5.7E-29 T 12-10-2018 AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 Gene3D G3DSA:3.40.50.300 717 957 1.5E-19 T 12-10-2018 AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 Gene3D G3DSA:3.40.50.300 1055 1247 1.6E-27 T 12-10-2018 AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 Pfam PF13086 AAA domain 302 492 8.0E-20 T 12-10-2018 AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 Pfam PF13086 AAA domain 758 931 4.5E-14 T 12-10-2018 AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 Pfam PF13087 AAA domain 1032 1235 8.4E-25 T 12-10-2018 AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 SUPERFAMILY SSF52540 1027 1261 8.42E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29565 674c5961952ca4fd71d408219e0e8676 1277 SUPERFAMILY SSF52540 292 930 6.81E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00895 a7776f3080472c17574fd91767395328 301 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 130 145 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFR_00895 a7776f3080472c17574fd91767395328 301 SUPERFAMILY SSF48576 8 290 2.3E-78 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_00895 a7776f3080472c17574fd91767395328 301 Gene3D G3DSA:1.10.600.10 2 289 3.1E-86 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_00895 a7776f3080472c17574fd91767395328 301 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 161 186 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFR_00895 a7776f3080472c17574fd91767395328 301 Pfam PF00494 Squalene/phytoene synthase 17 277 4.5E-70 T 12-10-2018 AFR_23170 a90ccb89b04f6a90336a7ca8951732f0 281 Pfam PF01061 ABC-2 type transporter 25 218 8.6E-19 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_23170 a90ccb89b04f6a90336a7ca8951732f0 281 PIRSF PIRSF006648 11 264 8.7E-16 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_22105 ebd8594df2568a41f2b3867634dc7f20 396 Gene3D G3DSA:1.50.10.100 54 334 3.7E-24 T 12-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 AFR_22105 ebd8594df2568a41f2b3867634dc7f20 396 SUPERFAMILY SSF48230 48 337 1.28E-42 T 12-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 AFR_22105 ebd8594df2568a41f2b3867634dc7f20 396 Pfam PF05426 Alginate lyase 104 249 3.8E-12 T 12-10-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 AFR_02730 748492394836d492b7f7fbe67c87510d 123 Pfam PF13788 Domain of unknown function (DUF4180) 9 118 2.1E-42 T 12-10-2018 IPR025438 Domain of unknown function DUF4180 AFR_40595 847f19a436925ef018dd434adf71c199 779 Gene3D G3DSA:3.30.565.10 289 475 2.0E-58 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40595 847f19a436925ef018dd434adf71c199 779 SMART SM00260 632 760 9.1E-7 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40595 847f19a436925ef018dd434adf71c199 779 SMART SM00260 468 607 5.5E-29 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40595 847f19a436925ef018dd434adf71c199 779 Gene3D G3DSA:1.20.120.160 1 142 3.2E-35 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFR_40595 847f19a436925ef018dd434adf71c199 779 Pfam PF01584 CheW-like domain 480 609 4.3E-23 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40595 847f19a436925ef018dd434adf71c199 779 Pfam PF01584 CheW-like domain 637 758 6.7E-15 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40595 847f19a436925ef018dd434adf71c199 779 SMART SM00073 4 101 3.2E-19 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFR_40595 847f19a436925ef018dd434adf71c199 779 SUPERFAMILY SSF47226 4 125 2.22E-26 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFR_40595 847f19a436925ef018dd434adf71c199 779 Gene3D G3DSA:1.10.287.560 229 288 2.8E-18 T 12-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 AFR_40595 847f19a436925ef018dd434adf71c199 779 SUPERFAMILY SSF55874 291 474 8.64E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40595 847f19a436925ef018dd434adf71c199 779 SUPERFAMILY SSF160246 165 255 1.28E-5 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily AFR_40595 847f19a436925ef018dd434adf71c199 779 Pfam PF01627 Hpt domain 6 103 2.0E-14 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFR_40595 847f19a436925ef018dd434adf71c199 779 SMART SM00387 333 476 1.1E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_40595 847f19a436925ef018dd434adf71c199 779 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 475 9.5E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_40595 847f19a436925ef018dd434adf71c199 779 Gene3D G3DSA:2.40.50.180 658 718 6.7E-14 T 12-10-2018 AFR_40595 847f19a436925ef018dd434adf71c199 779 Gene3D G3DSA:2.40.50.180 499 562 2.4E-35 T 12-10-2018 AFR_40595 847f19a436925ef018dd434adf71c199 779 SUPERFAMILY SSF50341 636 757 1.7E-17 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_40595 847f19a436925ef018dd434adf71c199 779 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 229 288 6.5E-15 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFR_40595 847f19a436925ef018dd434adf71c199 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 2.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40595 847f19a436925ef018dd434adf71c199 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 2.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40595 847f19a436925ef018dd434adf71c199 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 2.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40595 847f19a436925ef018dd434adf71c199 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 2.5E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40595 847f19a436925ef018dd434adf71c199 779 SUPERFAMILY SSF47384 230 289 5.49E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_40595 847f19a436925ef018dd434adf71c199 779 Gene3D G3DSA:2.30.30.40 476 603 2.4E-35 T 12-10-2018 AFR_40595 847f19a436925ef018dd434adf71c199 779 SUPERFAMILY SSF50341 475 606 2.09E-28 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_40595 847f19a436925ef018dd434adf71c199 779 SMART SM01231 228 288 4.6E-16 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFR_36415 a5327b33733e7ab368f149e2b75c2828 751 Pfam PF01966 HD domain 415 518 3.6E-9 T 12-10-2018 IPR006674 HD domain AFR_36415 a5327b33733e7ab368f149e2b75c2828 751 SUPERFAMILY SSF81301 28 146 2.43E-13 T 12-10-2018 AFR_36415 a5327b33733e7ab368f149e2b75c2828 751 Gene3D G3DSA:1.10.3210.10 403 528 1.9E-6 T 12-10-2018 AFR_36415 a5327b33733e7ab368f149e2b75c2828 751 SUPERFAMILY SSF55021 683 745 2.96E-6 T 12-10-2018 AFR_36415 a5327b33733e7ab368f149e2b75c2828 751 SUPERFAMILY SSF109604 380 531 1.22E-14 T 12-10-2018 AFR_36415 a5327b33733e7ab368f149e2b75c2828 751 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 751 56.7 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 Pfam PF03471 Transporter associated domain 333 411 3.4E-14 T 12-10-2018 IPR005170 Transporter-associated domain AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 Pfam PF01595 Domain of unknown function DUF21 1 182 1.3E-43 T 12-10-2018 IPR002550 CNNM, transmembrane domain AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 SUPERFAMILY SSF56176 331 420 1.17E-14 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 Pfam PF00571 CBS domain 272 317 6.7E-7 T 12-10-2018 IPR000644 CBS domain AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 SMART SM01091 332 413 1.7E-16 T 12-10-2018 IPR005170 Transporter-associated domain AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 Gene3D G3DSA:3.10.580.10 182 323 1.9E-37 T 12-10-2018 AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 Gene3D G3DSA:3.30.465.10 324 412 1.5E-16 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 SUPERFAMILY SSF54631 199 334 3.05E-23 T 12-10-2018 AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 SMART SM00116 269 317 15.0 T 12-10-2018 IPR000644 CBS domain AFR_34975 35f64ba0900f49da3d2324afa30bc838 421 SMART SM00116 211 261 0.22 T 12-10-2018 IPR000644 CBS domain AFR_20300 958524633c77e6b17c3c4a4e547ecdc7 284 Pfam PF12730 ABC-2 family transporter protein 72 213 1.2E-11 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_11105 c465baf0f30281be0a7c349f462aa534 316 Gene3D G3DSA:1.10.10.10 241 315 4.7E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11105 c465baf0f30281be0a7c349f462aa534 316 Pfam PF12840 Helix-turn-helix domain 251 298 1.8E-6 T 12-10-2018 AFR_11105 c465baf0f30281be0a7c349f462aa534 316 SUPERFAMILY SSF46785 255 302 1.57E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11105 c465baf0f30281be0a7c349f462aa534 316 SMART SM00418 242 312 0.0056 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 SUPERFAMILY SSF51419 38 277 2.29E-64 T 12-10-2018 IPR029066 PLP-binding barrel AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 275 1.6E-53 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 276 370 6.7E-11 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 60 78 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 Gene3D G3DSA:2.40.37.10 274 382 8.0E-95 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 SUPERFAMILY SSF50621 259 392 7.53E-29 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 Gene3D G3DSA:3.20.20.10 50 273 8.0E-95 T 12-10-2018 IPR029066 PLP-binding barrel AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 220 233 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01182 Ornithine decarboxylase signature 357 370 2.7E-27 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01182 Ornithine decarboxylase signature 102 126 2.7E-27 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01182 Ornithine decarboxylase signature 58 85 2.7E-27 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01182 Ornithine decarboxylase signature 132 154 2.7E-27 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01182 Ornithine decarboxylase signature 32 56 2.7E-27 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01182 Ornithine decarboxylase signature 336 346 2.7E-27 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 80 92 3.2E-25 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 60 78 3.2E-25 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 370 383 3.2E-25 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 182 195 3.2E-25 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_33705 92b57a7f7a33aaa4d6330be91d1a0cf0 414 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 265 284 3.2E-25 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_34355 c7e5f83348c36aba22b3925f6e9871ff 230 Pfam PF00857 Isochorismatase family 26 213 1.2E-44 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_34355 c7e5f83348c36aba22b3925f6e9871ff 230 Gene3D G3DSA:3.40.50.850 22 229 1.9E-61 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_34355 c7e5f83348c36aba22b3925f6e9871ff 230 SUPERFAMILY SSF52499 13 227 1.05E-58 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_16925 aae5b7ad33aa1926abd396fa0d3396bd 333 SMART SM00861 11 186 9.5E-73 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_16925 aae5b7ad33aa1926abd396fa0d3396bd 333 Pfam PF02780 Transketolase, C-terminal domain 200 321 9.8E-35 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFR_16925 aae5b7ad33aa1926abd396fa0d3396bd 333 SUPERFAMILY SSF52922 199 327 9.95E-36 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_16925 aae5b7ad33aa1926abd396fa0d3396bd 333 Gene3D G3DSA:3.40.50.920 200 329 3.2E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_16925 aae5b7ad33aa1926abd396fa0d3396bd 333 SUPERFAMILY SSF52518 10 190 7.28E-71 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_16925 aae5b7ad33aa1926abd396fa0d3396bd 333 Gene3D G3DSA:3.40.50.970 8 199 1.0E-76 T 12-10-2018 AFR_16925 aae5b7ad33aa1926abd396fa0d3396bd 333 Pfam PF02779 Transketolase, pyrimidine binding domain 10 184 1.4E-47 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_39020 316a78b36999824e1ef05bb601a977b2 552 SUPERFAMILY SSF52317 13 235 3.2E-46 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_39020 316a78b36999824e1ef05bb601a977b2 552 Pfam PF06283 Trehalose utilisation 16 226 1.9E-81 T 12-10-2018 IPR029010 ThuA-like domain AFR_39020 316a78b36999824e1ef05bb601a977b2 552 Gene3D G3DSA:2.80.10.50 422 551 3.6E-41 T 12-10-2018 AFR_39020 316a78b36999824e1ef05bb601a977b2 552 Pfam PF06439 Domain of Unknown Function (DUF1080) 239 413 9.8E-38 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 AFR_39020 316a78b36999824e1ef05bb601a977b2 552 Gene3D G3DSA:3.40.50.880 3 235 3.3E-87 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_39020 316a78b36999824e1ef05bb601a977b2 552 Pfam PF00652 Ricin-type beta-trefoil lectin domain 426 547 2.0E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_39020 316a78b36999824e1ef05bb601a977b2 552 SUPERFAMILY SSF50370 419 549 9.04E-40 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_39020 316a78b36999824e1ef05bb601a977b2 552 Gene3D G3DSA:2.60.120.560 238 418 1.8E-41 T 12-10-2018 AFR_39020 316a78b36999824e1ef05bb601a977b2 552 SMART SM00458 423 550 8.5E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_02705 294adb21e110e703ed41048946a4175a 443 Pfam PF00501 AMP-binding enzyme 110 356 7.7E-45 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_02705 294adb21e110e703ed41048946a4175a 443 Gene3D G3DSA:3.40.50.12780 13 352 5.6E-64 T 12-10-2018 AFR_02705 294adb21e110e703ed41048946a4175a 443 ProSitePatterns PS00455 Putative AMP-binding domain signature. 121 132 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_02705 294adb21e110e703ed41048946a4175a 443 SUPERFAMILY SSF56801 22 442 9.29E-76 T 12-10-2018 AFR_02705 294adb21e110e703ed41048946a4175a 443 Gene3D G3DSA:3.30.300.30 358 443 7.8E-7 T 12-10-2018 AFR_27180 9d636d5f598ba698eda5c502ed95fcfd 409 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 145 1.1E-22 T 12-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G AFR_27180 9d636d5f598ba698eda5c502ed95fcfd 409 SUPERFAMILY SSF55961 1 146 1.55E-34 T 12-10-2018 AFR_27180 9d636d5f598ba698eda5c502ed95fcfd 409 Gene3D G3DSA:3.30.530.20 1 155 1.5E-45 T 12-10-2018 IPR023393 START-like domain superfamily AFR_37190 b570fc26f31497b04c5aae1b1f9240d0 505 SMART SM00267 337 501 3.3E-48 T 12-10-2018 IPR000160 GGDEF domain AFR_37190 b570fc26f31497b04c5aae1b1f9240d0 505 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 344 497 5.3E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_37190 b570fc26f31497b04c5aae1b1f9240d0 505 Pfam PF00990 Diguanylate cyclase, GGDEF domain 348 497 1.1E-36 T 12-10-2018 IPR000160 GGDEF domain AFR_37190 b570fc26f31497b04c5aae1b1f9240d0 505 SUPERFAMILY SSF55073 353 497 4.55E-39 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_37190 b570fc26f31497b04c5aae1b1f9240d0 505 Gene3D G3DSA:3.30.70.270 342 501 8.4E-48 T 12-10-2018 AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 SUPERFAMILY SSF51735 6 253 9.47E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 0.0059 T 12-10-2018 AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.3E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 1.8E-57 T 12-10-2018 AFR_28905 4f95a293316d0520166dd53c31e4fa52 255 Gene3D G3DSA:3.40.50.720 1 254 3.2E-78 T 12-10-2018 AFR_03585 b30ff353bc20fd7830f4c36fd0bfacb8 220 Pfam PF03713 Domain of unknown function (DUF305) 79 220 3.5E-43 T 12-10-2018 IPR005183 Domain of unknown function DUF305 AFR_03585 b30ff353bc20fd7830f4c36fd0bfacb8 220 Gene3D G3DSA:1.20.1260.10 68 220 3.5E-50 T 12-10-2018 IPR012347 Ferritin-like AFR_13995 26470888e008b1d780345a228265c4b1 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 312 3.4E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_13995 26470888e008b1d780345a228265c4b1 319 SUPERFAMILY SSF52540 7 262 1.45E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13995 26470888e008b1d780345a228265c4b1 319 Pfam PF00005 ABC transporter 32 186 7.3E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_13995 26470888e008b1d780345a228265c4b1 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 295 3.5E-14 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_13995 26470888e008b1d780345a228265c4b1 319 Gene3D G3DSA:3.40.50.300 8 316 1.2E-76 T 12-10-2018 AFR_13995 26470888e008b1d780345a228265c4b1 319 SMART SM00382 39 234 7.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 184 8.5E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 Pfam PF08281 Sigma-70, region 4 130 181 5.0E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 SUPERFAMILY SSF88946 14 110 3.4E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 59 90 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 Pfam PF04542 Sigma-70 region 2 38 103 3.4E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 SUPERFAMILY SSF88659 124 186 2.01E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 Gene3D G3DSA:1.10.10.10 124 189 1.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14025 a69ad49151d6ae4b66194c67e3b207e5 196 Gene3D G3DSA:1.10.1740.10 14 100 1.1E-27 T 12-10-2018 AFR_11355 99e0b2556a6fd07217d101db341a45c9 259 Pfam PF01925 Sulfite exporter TauE/SafE 9 249 6.4E-36 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 SUPERFAMILY SSF50494 202 383 6.85E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 Gene3D G3DSA:2.40.10.10 213 385 3.4E-67 T 12-10-2018 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 Gene3D G3DSA:3.30.300.50 124 193 8.7E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 Gene3D G3DSA:2.40.10.10 276 374 3.4E-67 T 12-10-2018 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 PIRSF PIRSF001134 1 390 3.6E-117 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 337 348 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 Pfam PF02983 Alpha-lytic protease prodomain 125 182 1.6E-20 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 Pfam PF00089 Trypsin 202 379 2.0E-13 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 227 241 1.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 352 366 1.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 328 351 1.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 309 326 1.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 288 308 1.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 AFR_35835 c070d75aef2e04bf7a5040fbaa4f7fc8 440 Gene3D G3DSA:3.30.300.50 41 118 1.1E-11 T 12-10-2018 IPR035070 Streptogrisin prodomain AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 Gene3D G3DSA:1.10.860.10 38 203 1.8E-56 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 Pfam PF03796 DnaB-like helicase C terminal domain 222 475 8.0E-105 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 43 477 2.6E-160 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 Gene3D G3DSA:3.40.50.300 205 479 1.3E-103 T 12-10-2018 AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 SMART SM00382 239 436 3.3E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 Pfam PF00772 DnaB-like helicase N terminal domain 43 144 1.4E-33 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 SUPERFAMILY SSF48024 41 152 8.11E-36 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 AFR_42805 177022f87ae8df3c14dc1602ee90b039 480 SUPERFAMILY SSF52540 220 465 1.98E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24435 ee5c2f34f0b7f98e473a519c171e13e3 115 Gene3D G3DSA:3.30.70.1060 1 115 2.1E-34 T 12-10-2018 AFR_24435 ee5c2f34f0b7f98e473a519c171e13e3 115 Pfam PF03795 YCII-related domain 3 113 7.5E-22 T 12-10-2018 IPR005545 YCII-related AFR_24435 ee5c2f34f0b7f98e473a519c171e13e3 115 SUPERFAMILY SSF54909 3 111 4.56E-26 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 Gene3D G3DSA:2.180.10.10 1159 1777 1.0E-42 T 12-10-2018 AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 Pfam PF05593 RHS Repeat 1239 1270 2.1E-5 T 12-10-2018 IPR031325 RHS repeat AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1239 1267 4.3E-6 T 12-10-2018 IPR006530 YD repeat AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 2110 2134 0.0052 T 12-10-2018 IPR030934 Intein C-terminal splicing region AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 SUPERFAMILY SSF51294 1993 2132 1.83E-18 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 Gene3D G3DSA:2.170.16.10 1989 2133 1.4E-37 T 12-10-2018 AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 SMART SM00306 1990 2091 3.1E-6 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1700 1777 9.6E-18 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 AFR_32600 1f3460885ce06dc9ba6ff2221ac4389f 2237 Pfam PF07591 Pretoxin HINT domain 2003 2133 3.5E-21 T 12-10-2018 AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 SUPERFAMILY SSF52833 362 473 1.4E-7 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 Gene3D G3DSA:3.30.70.2450 175 249 1.9E-94 T 12-10-2018 AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 Gene3D G3DSA:3.50.50.60 3 318 1.9E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 Gene3D G3DSA:3.40.30.120 342 471 2.5E-9 T 12-10-2018 AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 Pfam PF01494 FAD binding domain 2 317 1.3E-68 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 SUPERFAMILY SSF51905 2 327 2.1E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 291 2.0E-34 T 12-10-2018 AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 260 275 2.0E-34 T 12-10-2018 AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 2.0E-34 T 12-10-2018 AFR_09765 4a21aaf84ee0ce840a19eb11bab1c0a2 479 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.0E-34 T 12-10-2018 AFR_24860 5f26a58208996d05d1b0bc93ee2a9ea3 202 Gene3D G3DSA:3.10.50.40 90 201 2.6E-28 T 12-10-2018 AFR_24860 5f26a58208996d05d1b0bc93ee2a9ea3 202 SUPERFAMILY SSF54534 29 198 1.71E-27 T 12-10-2018 AFR_24860 5f26a58208996d05d1b0bc93ee2a9ea3 202 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 110 198 1.2E-20 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFR_10555 e6d1d33a2122403bf7831f7955928a93 486 Hamap MF_00973 Gluconeogenesis factor. 129 484 29.737 T 12-10-2018 IPR010119 Gluconeogenesis factor AFR_10555 e6d1d33a2122403bf7831f7955928a93 486 Pfam PF01933 Uncharacterised protein family UPF0052 133 436 3.7E-57 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 AFR_10555 e6d1d33a2122403bf7831f7955928a93 486 SUPERFAMILY SSF142338 130 478 2.22E-72 T 12-10-2018 AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 Pfam PF03946 Ribosomal protein L11, N-terminal domain 10 65 8.7E-11 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 SUPERFAMILY SSF46906 68 139 4.97E-24 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 SUPERFAMILY SSF54747 5 84 1.16E-12 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 Gene3D G3DSA:1.10.10.250 73 140 1.7E-27 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 41 73 1.0E-5 T 12-10-2018 AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 6 140 22.45 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 Gene3D G3DSA:3.30.1550.10 4 72 3.2E-12 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 SMART SM00649 10 140 3.2E-47 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFR_10500 7de5c48d9141c87c50c2baa31f12e309 140 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.2E-23 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AFR_29035 27a43ac06743c15d2821d9eb54c0e004 172 SUPERFAMILY SSF55781 32 168 1.18E-17 T 12-10-2018 AFR_29035 27a43ac06743c15d2821d9eb54c0e004 172 Pfam PF01590 GAF domain 33 163 1.1E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_29035 27a43ac06743c15d2821d9eb54c0e004 172 Gene3D G3DSA:3.30.450.40 20 171 2.0E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_42995 2319728e94e03ee5b3196fce4dcbcd1c 76 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 63 7.6E-13 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFR_42995 2319728e94e03ee5b3196fce4dcbcd1c 76 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 12 26 - T 12-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 AFR_42995 2319728e94e03ee5b3196fce4dcbcd1c 76 SUPERFAMILY SSF54211 2 69 4.3E-16 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_42995 2319728e94e03ee5b3196fce4dcbcd1c 76 Pfam PF00825 Ribonuclease P 2 68 3.3E-18 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFR_42995 2319728e94e03ee5b3196fce4dcbcd1c 76 Gene3D G3DSA:3.30.230.10 1 75 9.1E-17 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_15790 6bed600615aa8d0efc628aaec2f46489 198 Pfam PF13649 Methyltransferase domain 37 114 3.0E-19 T 12-10-2018 AFR_15790 6bed600615aa8d0efc628aaec2f46489 198 Gene3D G3DSA:3.40.50.150 2 185 6.0E-42 T 12-10-2018 AFR_15790 6bed600615aa8d0efc628aaec2f46489 198 SUPERFAMILY SSF53335 3 174 1.96E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_00325 0c56c7902fe75cd00cd3095ed9534b6c 713 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 389 400 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_00325 0c56c7902fe75cd00cd3095ed9534b6c 713 SUPERFAMILY SSF103501 13 206 6.8E-5 T 12-10-2018 IPR036197 NarG-like superfamily AFR_00325 0c56c7902fe75cd00cd3095ed9534b6c 713 Pfam PF02754 Cysteine-rich domain 593 680 2.6E-17 T 12-10-2018 IPR004017 Cysteine-rich domain AFR_00325 0c56c7902fe75cd00cd3095ed9534b6c 713 Pfam PF02754 Cysteine-rich domain 469 554 1.4E-18 T 12-10-2018 IPR004017 Cysteine-rich domain AFR_00325 0c56c7902fe75cd00cd3095ed9534b6c 713 SUPERFAMILY SSF46548 280 417 3.66E-22 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_00325 0c56c7902fe75cd00cd3095ed9534b6c 713 Gene3D G3DSA:1.10.1060.10 353 422 3.8E-5 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_00325 0c56c7902fe75cd00cd3095ed9534b6c 713 Pfam PF13183 4Fe-4S dicluster domain 295 403 3.9E-13 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_18880 21bdb6bd3dd513d47b485b5c38367c16 666 SUPERFAMILY SSF51445 18 375 4.66E-111 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_18880 21bdb6bd3dd513d47b485b5c38367c16 666 Gene3D G3DSA:3.20.20.80 2 398 4.1E-137 T 12-10-2018 AFR_18880 21bdb6bd3dd513d47b485b5c38367c16 666 Gene3D G3DSA:3.40.50.880 403 609 3.0E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_18880 21bdb6bd3dd513d47b485b5c38367c16 666 Pfam PF02449 Beta-galactosidase 24 394 4.0E-150 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_18880 21bdb6bd3dd513d47b485b5c38367c16 666 SUPERFAMILY SSF52317 404 605 1.68E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_18880 21bdb6bd3dd513d47b485b5c38367c16 666 PIRSF PIRSF001084 11 664 1.1E-248 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_18880 21bdb6bd3dd513d47b485b5c38367c16 666 Pfam PF08532 Beta-galactosidase trimerisation domain 406 604 4.9E-59 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 SUPERFAMILY SSF55781 24 171 2.18E-19 T 12-10-2018 AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 SUPERFAMILY SSF52172 160 228 3.83E-8 T 12-10-2018 IPR011006 CheY-like superfamily AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 Pfam PF13185 GAF domain 23 161 6.8E-15 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 SMART SM00065 24 171 3.0E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 PIRSF PIRSF036625 1 237 1.1E-50 T 12-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 SMART SM01012 173 228 1.5E-21 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 Pfam PF03861 ANTAR domain 176 228 3.0E-20 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 Gene3D G3DSA:3.30.450.40 10 175 3.1E-22 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_16625 9b7c4e158c8817ab2f31924c006325d9 244 Gene3D G3DSA:1.10.10.10 176 235 9.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 SUPERFAMILY SSF51735 4 258 8.61E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 Pfam PF00106 short chain dehydrogenase 6 189 1.8E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 9.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 9.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 1.7E-5 T 12-10-2018 AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_37660 3dc278ae7c07fb39f36e3a667fc76cc2 281 Gene3D G3DSA:3.40.50.720 2 279 1.8E-84 T 12-10-2018 AFR_30645 baa6266e1707575e01731841cacbcfc7 136 SUPERFAMILY SSF48013 4 130 1.2E-36 T 12-10-2018 IPR035926 NusB-like superfamily AFR_30645 baa6266e1707575e01731841cacbcfc7 136 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 2 135 22.043 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 AFR_30645 baa6266e1707575e01731841cacbcfc7 136 Gene3D G3DSA:1.10.940.10 1 136 2.1E-41 T 12-10-2018 IPR035926 NusB-like superfamily AFR_30645 baa6266e1707575e01731841cacbcfc7 136 Pfam PF01029 NusB family 5 131 3.4E-32 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFR_30645 baa6266e1707575e01731841cacbcfc7 136 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 132 5.9E-39 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 AFR_15175 22bfbce68b5bf8796b6944336ee3bf4d 180 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 43 173 4.9E-35 T 12-10-2018 IPR005247 YbhB/YbcL AFR_15175 22bfbce68b5bf8796b6944336ee3bf4d 180 Gene3D G3DSA:3.90.280.10 1 177 5.8E-55 T 12-10-2018 IPR036610 PEBP-like superfamily AFR_15175 22bfbce68b5bf8796b6944336ee3bf4d 180 SUPERFAMILY SSF49777 17 175 7.98E-50 T 12-10-2018 IPR036610 PEBP-like superfamily AFR_15175 22bfbce68b5bf8796b6944336ee3bf4d 180 Pfam PF01161 Phosphatidylethanolamine-binding protein 39 175 1.1E-34 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein AFR_27830 a5964a678fa79cf61008ca1b8ba5f107 127 Gene3D G3DSA:1.10.10.10 14 127 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27830 a5964a678fa79cf61008ca1b8ba5f107 127 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 3.3E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_27830 a5964a678fa79cf61008ca1b8ba5f107 127 SMART SM00345 21 80 9.4E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_27830 a5964a678fa79cf61008ca1b8ba5f107 127 SUPERFAMILY SSF46785 12 84 2.73E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_35300 ca9e6629564b0954569b4b56396eab98 160 Pfam PF11292 Protein of unknown function (DUF3093) 16 155 8.4E-45 T 12-10-2018 IPR021443 Protein of unknown function DUF3093 AFR_06255 003e356fd6034ee5d7d28e4c61f6a6fb 193 SMART SM00849 22 182 5.4E-32 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_06255 003e356fd6034ee5d7d28e4c61f6a6fb 193 Pfam PF00753 Metallo-beta-lactamase superfamily 23 182 1.7E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_06255 003e356fd6034ee5d7d28e4c61f6a6fb 193 Gene3D G3DSA:3.60.15.10 16 193 5.4E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_06255 003e356fd6034ee5d7d28e4c61f6a6fb 193 SUPERFAMILY SSF56281 18 192 2.75E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_26625 b5b6e952ce37fd790f4e2bf579747d1f 355 Gene3D G3DSA:3.20.20.70 1 355 3.6E-120 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_26625 b5b6e952ce37fd790f4e2bf579747d1f 355 SUPERFAMILY SSF51395 2 353 1.23E-107 T 12-10-2018 AFR_26625 b5b6e952ce37fd790f4e2bf579747d1f 355 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 329 2.8E-71 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFR_19165 80f35c77deb95e659f9454d92cb98207 743 Gene3D G3DSA:3.30.450.20 175 315 1.4E-16 T 12-10-2018 AFR_19165 80f35c77deb95e659f9454d92cb98207 743 SUPERFAMILY SSF55785 176 302 4.76E-13 T 12-10-2018 IPR035965 PAS domain superfamily AFR_19165 80f35c77deb95e659f9454d92cb98207 743 SMART SM00052 480 727 3.6E-95 T 12-10-2018 IPR001633 EAL domain AFR_19165 80f35c77deb95e659f9454d92cb98207 743 SMART SM00267 304 470 7.9E-47 T 12-10-2018 IPR000160 GGDEF domain AFR_19165 80f35c77deb95e659f9454d92cb98207 743 Pfam PF00563 EAL domain 486 722 1.8E-66 T 12-10-2018 IPR001633 EAL domain AFR_19165 80f35c77deb95e659f9454d92cb98207 743 Gene3D G3DSA:3.20.20.450 484 741 3.9E-87 T 12-10-2018 IPR035919 EAL domain superfamily AFR_19165 80f35c77deb95e659f9454d92cb98207 743 Pfam PF08448 PAS fold 195 305 2.1E-10 T 12-10-2018 IPR013656 PAS fold-4 AFR_19165 80f35c77deb95e659f9454d92cb98207 743 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 312 469 2.5E-28 T 12-10-2018 IPR000160 GGDEF domain AFR_19165 80f35c77deb95e659f9454d92cb98207 743 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 186 311 4.3E-6 T 12-10-2018 IPR000014 PAS domain AFR_19165 80f35c77deb95e659f9454d92cb98207 743 Pfam PF00990 Diguanylate cyclase, GGDEF domain 317 466 2.8E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_19165 80f35c77deb95e659f9454d92cb98207 743 SUPERFAMILY SSF55073 320 472 1.88E-36 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_19165 80f35c77deb95e659f9454d92cb98207 743 SUPERFAMILY SSF141868 485 736 1.29E-78 T 12-10-2018 IPR035919 EAL domain superfamily AFR_19165 80f35c77deb95e659f9454d92cb98207 743 Gene3D G3DSA:3.30.70.270 316 483 4.3E-44 T 12-10-2018 AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 ProSitePatterns PS00211 ABC transporters family signature. 411 425 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 SMART SM00382 32 222 2.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 SMART SM00382 291 486 1.6E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 Gene3D G3DSA:3.40.50.300 2 235 1.5E-55 T 12-10-2018 AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 Pfam PF00005 ABC transporter 283 438 7.4E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 Gene3D G3DSA:3.40.50.300 250 515 1.5E-37 T 12-10-2018 AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 Pfam PF00005 ABC transporter 23 174 7.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 SUPERFAMILY SSF52540 7 228 5.88E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27640 04c5da73fe35dd242a4b8b34239a6103 515 SUPERFAMILY SSF52540 251 490 9.69E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 Hamap MF_00743 Fumarate hydratase class II [fumC]. 9 466 79.079 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 Gene3D G3DSA:1.20.200.10 138 406 1.8E-111 T 12-10-2018 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 SUPERFAMILY SSF48557 9 464 5.01E-145 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 Pfam PF00206 Lyase 17 341 1.2E-100 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 Gene3D G3DSA:1.10.40.30 407 463 9.7E-24 T 12-10-2018 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 PRINTS PR00145 Argininosuccinate lyase family signature 132 154 1.8E-6 T 12-10-2018 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 1.8E-6 T 12-10-2018 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 1.8E-6 T 12-10-2018 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 Pfam PF10415 Fumarase C C-terminus 407 465 1.3E-21 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 Gene3D G3DSA:1.10.275.10 10 137 5.5E-51 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 9.1E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 9.1E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 9.1E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFR_41115 1b96ad3973bad5ef6bf7a113ef92632e 466 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 9.1E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFR_11265 05335d5ec29d0a4e3a43a806ab1df574 141 Gene3D G3DSA:3.30.450.30 10 135 7.1E-40 T 12-10-2018 AFR_11265 05335d5ec29d0a4e3a43a806ab1df574 141 Pfam PF03259 Roadblock/LC7 domain 13 103 1.6E-22 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_11265 05335d5ec29d0a4e3a43a806ab1df574 141 SUPERFAMILY SSF103196 10 133 3.31E-26 T 12-10-2018 AFR_11265 05335d5ec29d0a4e3a43a806ab1df574 141 SMART SM00960 14 104 7.3E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_23295 e2b74d2a9bc8d1d7f1b8a1e9d3fad467 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23295 e2b74d2a9bc8d1d7f1b8a1e9d3fad467 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23295 e2b74d2a9bc8d1d7f1b8a1e9d3fad467 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23295 e2b74d2a9bc8d1d7f1b8a1e9d3fad467 265 Pfam PF00106 short chain dehydrogenase 3 199 1.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23295 e2b74d2a9bc8d1d7f1b8a1e9d3fad467 265 SUPERFAMILY SSF51735 2 235 2.34E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23295 e2b74d2a9bc8d1d7f1b8a1e9d3fad467 265 Gene3D G3DSA:3.40.50.720 2 265 6.6E-56 T 12-10-2018 AFR_37340 fefda9c2910cf8061918a30467938596 309 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.3E-30 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 PRINTS PR00126 ATP synthase gamma subunit signature 249 268 2.3E-30 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 PRINTS PR00126 ATP synthase gamma subunit signature 280 301 2.3E-30 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 PRINTS PR00126 ATP synthase gamma subunit signature 181 198 2.3E-30 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 Pfam PF00231 ATP synthase 5 302 9.9E-87 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 Gene3D G3DSA:1.10.287.80 8 298 9.1E-89 T 12-10-2018 AFR_37340 fefda9c2910cf8061918a30467938596 309 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 302 8.9E-97 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 302 33.641 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 Gene3D G3DSA:3.40.1380.10 61 221 9.1E-89 T 12-10-2018 AFR_37340 fefda9c2910cf8061918a30467938596 309 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 288 301 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37340 fefda9c2910cf8061918a30467938596 309 SUPERFAMILY SSF52943 5 302 8.76E-77 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_04905 51678f79e367980d212902fadbf8f8db 162 Gene3D G3DSA:3.90.960.10 3 162 3.4E-52 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_04905 51678f79e367980d212902fadbf8f8db 162 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 160 1.7E-50 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC AFR_04905 51678f79e367980d212902fadbf8f8db 162 Pfam PF04073 Aminoacyl-tRNA editing domain 41 152 1.9E-23 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFR_04905 51678f79e367980d212902fadbf8f8db 162 PIRSF PIRSF006181 5 162 5.1E-48 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC AFR_04905 51678f79e367980d212902fadbf8f8db 162 SUPERFAMILY SSF55826 10 160 5.23E-40 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 SMART SM00642 184 544 8.6E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 Gene3D G3DSA:2.60.40.10 1 178 4.2E-53 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 Pfam PF11896 Domain of unknown function (DUF3416) 1 178 2.6E-48 T 12-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 648 41.745 T 12-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 Gene3D G3DSA:2.60.40.1180 556 649 3.9E-27 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 Pfam PF00128 Alpha amylase, catalytic domain 214 315 1.5E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 SUPERFAMILY SSF51445 181 551 2.22E-81 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 Gene3D G3DSA:3.20.20.80 179 554 4.3E-157 T 12-10-2018 AFR_24190 6a9a41c7b867a3fc6085ce5d13fe974f 650 Gene3D G3DSA:1.20.58.280 80 159 4.2E-53 T 12-10-2018 AFR_04750 d23c54079af71bfa8d3acd90557d77b8 274 SUPERFAMILY SSF161098 71 254 2.09E-28 T 12-10-2018 IPR035906 MetI-like superfamily AFR_04750 d23c54079af71bfa8d3acd90557d77b8 274 Gene3D G3DSA:1.10.3720.10 66 263 7.9E-29 T 12-10-2018 IPR035906 MetI-like superfamily AFR_04750 d23c54079af71bfa8d3acd90557d77b8 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 268 1.5E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 Gene3D G3DSA:1.10.10.10 851 912 1.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 ProSitePatterns PS00622 LuxR-type HTH domain signature. 871 898 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 SUPERFAMILY SSF46894 848 908 1.8E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 SUPERFAMILY SSF48452 609 822 2.0E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 Pfam PF00196 Bacterial regulatory proteins, luxR family 856 907 1.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 Gene3D G3DSA:1.25.40.10 546 850 9.7E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 SMART SM00421 854 911 7.6E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 SUPERFAMILY SSF52540 2 220 3.5E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 Pfam PF13191 AAA ATPase domain 3 162 4.8E-18 T 12-10-2018 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 871 887 7.9E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 857 871 7.9E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12280 e14e2cac8efeb395559a789feea76b7e 913 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 887 899 7.9E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 49 71 4.7E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 220 232 4.7E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 166 181 4.7E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 187 209 4.7E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 Gene3D G3DSA:3.10.290.10 332 425 3.6E-24 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 Pfam PF00579 tRNA synthetases class I (W and Y) 35 327 2.1E-74 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 SUPERFAMILY SSF55174 330 422 1.14E-15 T 12-10-2018 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 7 423 43.055 T 12-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 Gene3D G3DSA:3.40.50.620 7 226 2.4E-80 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 SUPERFAMILY SSF52374 9 327 2.99E-101 T 12-10-2018 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 8 422 3.5E-112 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 Gene3D G3DSA:1.10.240.10 227 331 6.6E-36 T 12-10-2018 AFR_30000 367b816d2ba7dfd8a2da7e4c36981ec1 425 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 55 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 Pfam PF00271 Helicase conserved C-terminal domain 344 422 2.4E-4 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 SMART SM00487 14 201 6.9E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 Gene3D G3DSA:3.40.50.300 197 453 4.7E-56 T 12-10-2018 AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 Pfam PF08148 DSHCT (NUC185) domain 736 904 5.7E-38 T 12-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 Pfam PF00270 DEAD/DEAH box helicase 20 173 7.3E-19 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 SMART SM01142 733 909 1.5E-59 T 12-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 Gene3D G3DSA:3.40.50.300 6 196 1.7E-60 T 12-10-2018 AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 SMART SM00490 330 422 2.6E-14 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 Gene3D G3DSA:1.10.3380.30 691 904 1.8E-16 T 12-10-2018 AFR_26320 7889c4ba54ac791b1402ff3b741c5d5c 910 SUPERFAMILY SSF52540 28 436 2.13E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35680 5158895385b89fb18a0fb8ad47d5ff50 325 Pfam PF00268 Ribonucleotide reductase, small chain 4 288 2.0E-80 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35680 5158895385b89fb18a0fb8ad47d5ff50 325 PIRSF PIRSF000355 1 324 7.3E-108 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35680 5158895385b89fb18a0fb8ad47d5ff50 325 SUPERFAMILY SSF47240 4 312 3.94E-88 T 12-10-2018 IPR009078 Ferritin-like superfamily AFR_35680 5158895385b89fb18a0fb8ad47d5ff50 325 Gene3D G3DSA:1.10.620.20 1 312 5.1E-103 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 AFR_27205 1e219cc5fcd3498eee80c4d567860b2a 174 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 53 3.8E-6 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_27205 1e219cc5fcd3498eee80c4d567860b2a 174 Gene3D G3DSA:1.10.150.120 75 174 1.6E-32 T 12-10-2018 AFR_27205 1e219cc5fcd3498eee80c4d567860b2a 174 SUPERFAMILY SSF54292 2 78 2.75E-21 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_27205 1e219cc5fcd3498eee80c4d567860b2a 174 Gene3D G3DSA:3.10.20.30 1 74 7.8E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_27205 1e219cc5fcd3498eee80c4d567860b2a 174 SUPERFAMILY SSF47741 84 150 8.9E-32 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily AFR_27205 1e219cc5fcd3498eee80c4d567860b2a 174 Pfam PF01799 [2Fe-2S] binding domain 73 145 7.7E-30 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 SMART SM00231 753 891 0.18 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 SMART SM00231 893 1032 0.024 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 SUPERFAMILY SSF48208 285 707 3.23E-15 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Gene3D G3DSA:3.30.2080.10 312 726 1.4E-212 T 12-10-2018 AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 3 725 9.2E-141 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 SUPERFAMILY SSF49785 751 890 7.09E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Pfam PF07971 Glycosyl hydrolase family 92 255 722 5.3E-140 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Gene3D G3DSA:2.60.120.260 892 1031 8.2E-35 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Gene3D G3DSA:2.60.120.260 752 890 1.5E-36 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Gene3D G3DSA:2.70.98.10 32 363 1.4E-212 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Gene3D G3DSA:1.20.1050.60 364 458 1.4E-212 T 12-10-2018 AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Pfam PF00754 F5/8 type C domain 763 881 3.5E-14 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Pfam PF00754 F5/8 type C domain 905 1023 5.6E-15 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 SUPERFAMILY SSF49785 897 1016 2.06E-18 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_30070 19f18d41bd48b60e8336435a1f1159a6 1032 Gene3D G3DSA:1.20.1610.10 459 601 1.4E-212 T 12-10-2018 AFR_29625 1726a916e3cb1aa5c41002324ad9ed94 222 Pfam PF02224 Cytidylate kinase 8 216 1.7E-64 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFR_29625 1726a916e3cb1aa5c41002324ad9ed94 222 Gene3D G3DSA:3.40.50.300 2 221 2.6E-74 T 12-10-2018 AFR_29625 1726a916e3cb1aa5c41002324ad9ed94 222 SUPERFAMILY SSF52540 7 219 6.54E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29625 1726a916e3cb1aa5c41002324ad9ed94 222 Hamap MF_00238 Cytidylate kinase [cmk]. 6 220 29.249 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFR_29625 1726a916e3cb1aa5c41002324ad9ed94 222 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 214 1.8E-62 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFR_02670 2d392692c62163ba1314ca01a47588ef 244 Pfam PF02348 Cytidylyltransferase 5 184 1.7E-28 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 AFR_02670 2d392692c62163ba1314ca01a47588ef 244 SUPERFAMILY SSF53448 3 204 6.1E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02670 2d392692c62163ba1314ca01a47588ef 244 Gene3D G3DSA:3.90.550.10 2 211 1.4E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_34060 7c5b1c10c1b59376093dd3f5c2c3565d 156 Pfam PF00583 Acetyltransferase (GNAT) family 47 145 2.5E-9 T 12-10-2018 IPR000182 GNAT domain AFR_34060 7c5b1c10c1b59376093dd3f5c2c3565d 156 Gene3D G3DSA:3.40.630.30 1 155 3.2E-14 T 12-10-2018 AFR_34060 7c5b1c10c1b59376093dd3f5c2c3565d 156 SUPERFAMILY SSF55729 24 153 4.96E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_37065 1216b45cddc741e18056cb97980bc9e1 257 Gene3D G3DSA:1.10.12.10 199 257 1.4E-22 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFR_37065 1216b45cddc741e18056cb97980bc9e1 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 256 2.3E-68 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_37065 1216b45cddc741e18056cb97980bc9e1 257 Gene3D G3DSA:3.90.226.10 1 198 9.8E-71 T 12-10-2018 AFR_37065 1216b45cddc741e18056cb97980bc9e1 257 SUPERFAMILY SSF52096 3 257 3.65E-84 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_04445 561a63460114252f97bf22744b0b6c7b 181 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 5 162 24.126 T 12-10-2018 IPR022973 Ribosomal protein L10 AFR_04445 561a63460114252f97bf22744b0b6c7b 181 SUPERFAMILY SSF160369 6 172 3.79E-48 T 12-10-2018 AFR_04445 561a63460114252f97bf22744b0b6c7b 181 ProSitePatterns PS01109 Ribosomal protein L10 signature. 10 44 - T 12-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04445 561a63460114252f97bf22744b0b6c7b 181 Gene3D G3DSA:3.30.70.1730 2 171 1.3E-36 T 12-10-2018 AFR_04445 561a63460114252f97bf22744b0b6c7b 181 Pfam PF00466 Ribosomal protein L10 7 102 8.9E-24 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 AFR_02550 423273babec1b94acf96735f84678979 469 Gene3D G3DSA:3.10.20.90 7 88 2.2E-8 T 12-10-2018 AFR_02550 423273babec1b94acf96735f84678979 469 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 12 466 1.9E-57 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD AFR_02550 423273babec1b94acf96735f84678979 469 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 87 1.2E-14 T 12-10-2018 IPR024962 YukD-like AFR_02550 423273babec1b94acf96735f84678979 469 PIRSF PIRSF017804 1 469 8.7E-48 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD AFR_06190 776cfb85711e8adb7244e6327fbca91b 336 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 322 9.3E-47 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_06190 776cfb85711e8adb7244e6327fbca91b 336 Gene3D G3DSA:3.40.50.1100 8 329 2.6E-113 T 12-10-2018 AFR_06190 776cfb85711e8adb7244e6327fbca91b 336 SUPERFAMILY SSF53686 6 333 1.19E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_06190 776cfb85711e8adb7244e6327fbca91b 336 PIRSF PIRSF006278 1 336 3.9E-122 T 12-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase AFR_06190 776cfb85711e8adb7244e6327fbca91b 336 Gene3D G3DSA:3.40.50.1100 66 164 2.6E-113 T 12-10-2018 AFR_06190 776cfb85711e8adb7244e6327fbca91b 336 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 335 6.2E-165 T 12-10-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 AFR_29485 cd3bb90602ef8eed486a72e96c86950d 260 Pfam PF09234 Domain of unknown function (DUF1963) 52 253 3.7E-10 T 12-10-2018 IPR015315 Protein of unknown function DUF1963 AFR_29485 cd3bb90602ef8eed486a72e96c86950d 260 SUPERFAMILY SSF103032 51 254 3.27E-10 T 12-10-2018 IPR035948 YwqG-like superfamily AFR_02155 e7d23164bfad137f45f6a6e6a29493d3 381 Pfam PF07690 Major Facilitator Superfamily 14 335 4.2E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_02155 e7d23164bfad137f45f6a6e6a29493d3 381 SUPERFAMILY SSF103473 5 377 2.49E-40 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_02155 e7d23164bfad137f45f6a6e6a29493d3 381 Gene3D G3DSA:1.20.1250.20 3 183 4.5E-14 T 12-10-2018 AFR_02155 e7d23164bfad137f45f6a6e6a29493d3 381 Gene3D G3DSA:1.20.1250.20 192 378 5.2E-15 T 12-10-2018 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 1.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 Gene3D G3DSA:3.40.50.12740 2 217 4.6E-64 T 12-10-2018 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 SMART SM00421 155 212 1.7E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 SUPERFAMILY SSF52172 1 133 5.41E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 SUPERFAMILY SSF46894 148 217 1.19E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 SMART SM00448 2 115 2.6E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 Pfam PF00072 Response regulator receiver domain 4 115 9.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34045 2a48e7aa91b9a17a64c8996a132147bf 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_01830 53b4aa5d97ae997f4e8f3c48ce2fc892 266 Gene3D G3DSA:3.40.50.1000 6 217 2.6E-65 T 12-10-2018 IPR023214 HAD superfamily AFR_01830 53b4aa5d97ae997f4e8f3c48ce2fc892 266 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 193 6.5E-18 T 12-10-2018 AFR_01830 53b4aa5d97ae997f4e8f3c48ce2fc892 266 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 191 1.7E-30 T 12-10-2018 AFR_01830 53b4aa5d97ae997f4e8f3c48ce2fc892 266 Gene3D G3DSA:1.20.1440.100 17 92 2.6E-65 T 12-10-2018 AFR_01830 53b4aa5d97ae997f4e8f3c48ce2fc892 266 SUPERFAMILY SSF56784 5 209 4.38E-26 T 12-10-2018 IPR036412 HAD-like superfamily AFR_01830 53b4aa5d97ae997f4e8f3c48ce2fc892 266 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 5 204 2.4E-57 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like AFR_10195 33cc76f1381c932877487d373c60d65c 607 SUPERFAMILY SSF56801 7 602 9.16E-112 T 12-10-2018 AFR_10195 33cc76f1381c932877487d373c60d65c 607 Gene3D G3DSA:3.40.50.12780 3 304 1.6E-47 T 12-10-2018 AFR_10195 33cc76f1381c932877487d373c60d65c 607 Gene3D G3DSA:3.40.50.12780 326 466 7.0E-37 T 12-10-2018 AFR_10195 33cc76f1381c932877487d373c60d65c 607 Pfam PF00501 AMP-binding enzyme 17 470 7.0E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_10195 33cc76f1381c932877487d373c60d65c 607 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_41790 4d278e3bb21ee23a7488acf92e41522a 591 Gene3D G3DSA:3.10.105.10 329 559 5.6E-64 T 12-10-2018 AFR_41790 4d278e3bb21ee23a7488acf92e41522a 591 Gene3D G3DSA:3.40.190.10 36 328 8.5E-52 T 12-10-2018 AFR_41790 4d278e3bb21ee23a7488acf92e41522a 591 PIRSF PIRSF002741 16 584 4.9E-55 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFR_41790 4d278e3bb21ee23a7488acf92e41522a 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 106 500 2.1E-67 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFR_41790 4d278e3bb21ee23a7488acf92e41522a 591 SUPERFAMILY SSF53850 57 585 7.96E-89 T 12-10-2018 AFR_13450 d99969e2ddd45b216f27346611e5deae 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 194 300 6.4E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13450 d99969e2ddd45b216f27346611e5deae 476 SMART SM00387 189 302 3.3E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13450 d99969e2ddd45b216f27346611e5deae 476 SUPERFAMILY SSF55874 187 299 7.73E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13450 d99969e2ddd45b216f27346611e5deae 476 Gene3D G3DSA:3.30.565.10 152 300 6.7E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_35130 1c172879581a98149d9361f2fd840238 160 PIRSF PIRSF000194 1 159 8.1E-45 T 12-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 AFR_35130 1c172879581a98149d9361f2fd840238 160 Pfam PF00186 Dihydrofolate reductase 3 145 1.4E-42 T 12-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFR_35130 1c172879581a98149d9361f2fd840238 160 Gene3D G3DSA:3.40.430.10 1 157 2.8E-46 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_35130 1c172879581a98149d9361f2fd840238 160 SUPERFAMILY SSF53597 1 140 4.63E-46 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_35130 1c172879581a98149d9361f2fd840238 160 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 12-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 AFR_35130 1c172879581a98149d9361f2fd840238 160 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.8E-12 T 12-10-2018 AFR_35130 1c172879581a98149d9361f2fd840238 160 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.8E-12 T 12-10-2018 AFR_35130 1c172879581a98149d9361f2fd840238 160 PRINTS PR00070 Dihydrofolate reductase signature 92 106 1.8E-12 T 12-10-2018 AFR_35130 1c172879581a98149d9361f2fd840238 160 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.8E-12 T 12-10-2018 AFR_20165 5adb45a5697143c4946170e36c02fd9a 300 SUPERFAMILY SSF56112 47 277 1.25E-27 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_20165 5adb45a5697143c4946170e36c02fd9a 300 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 49 281 7.4E-51 T 12-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 AFR_20165 5adb45a5697143c4946170e36c02fd9a 300 Gene3D G3DSA:3.90.1200.10 119 239 2.8E-5 T 12-10-2018 AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 SUPERFAMILY SSF51735 6 246 4.5E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38885 190dff3392d326a4721e930759b1f42a 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 3.7E-55 T 12-10-2018 AFR_38885 190dff3392d326a4721e930759b1f42a 251 Gene3D G3DSA:3.40.50.720 2 249 3.5E-71 T 12-10-2018 AFR_38885 190dff3392d326a4721e930759b1f42a 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.7E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.7E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38885 190dff3392d326a4721e930759b1f42a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.7E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24220 a5358a0c124e2d1ccbcbbce3685b356a 188 Gene3D G3DSA:1.10.357.10 1 188 4.1E-51 T 12-10-2018 AFR_24220 a5358a0c124e2d1ccbcbbce3685b356a 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_24220 a5358a0c124e2d1ccbcbbce3685b356a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_24220 a5358a0c124e2d1ccbcbbce3685b356a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_24220 a5358a0c124e2d1ccbcbbce3685b356a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 2.5E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_24220 a5358a0c124e2d1ccbcbbce3685b356a 188 SUPERFAMILY SSF46689 4 75 1.89E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_25745 a3d9c3c4812f52a30d916508fc0ab623 217 Gene3D G3DSA:3.40.50.150 15 213 3.1E-43 T 12-10-2018 AFR_25745 a3d9c3c4812f52a30d916508fc0ab623 217 Pfam PF13578 Methyltransferase domain 77 180 1.9E-16 T 12-10-2018 AFR_25745 a3d9c3c4812f52a30d916508fc0ab623 217 SUPERFAMILY SSF53335 51 215 1.29E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_01765 074b8a39d7c017bd9f9e2e61070abd3c 574 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 2 346 7.3E-34 T 12-10-2018 IPR021368 Type VII secretion system protein EccE AFR_29210 24b72e29f04964e07447b1cea4301c82 952 SUPERFAMILY SSF48208 292 762 2.04E-86 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_29210 24b72e29f04964e07447b1cea4301c82 952 Gene3D G3DSA:2.60.40.1180 327 801 3.8E-227 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_29210 24b72e29f04964e07447b1cea4301c82 952 Gene3D G3DSA:2.70.98.50 62 326 3.8E-227 T 12-10-2018 AFR_29210 24b72e29f04964e07447b1cea4301c82 952 Gene3D G3DSA:1.50.10.10 58 752 3.8E-227 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_29210 24b72e29f04964e07447b1cea4301c82 952 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 860 936 9.4E-17 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29210 24b72e29f04964e07447b1cea4301c82 952 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 48 285 8.5E-68 T 12-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 AFR_29210 24b72e29f04964e07447b1cea4301c82 952 Gene3D G3DSA:2.80.10.50 811 951 2.3E-34 T 12-10-2018 AFR_29210 24b72e29f04964e07447b1cea4301c82 952 SMART SM00458 813 949 5.7E-10 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29210 24b72e29f04964e07447b1cea4301c82 952 SUPERFAMILY SSF50370 811 949 1.2E-35 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 PRINTS PR00173 Glutamate-aspartate symporter signature 29 49 2.7E-28 T 12-10-2018 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 PRINTS PR00173 Glutamate-aspartate symporter signature 216 235 2.7E-28 T 12-10-2018 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 PRINTS PR00173 Glutamate-aspartate symporter signature 100 125 2.7E-28 T 12-10-2018 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 PRINTS PR00173 Glutamate-aspartate symporter signature 70 90 2.7E-28 T 12-10-2018 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 PRINTS PR00173 Glutamate-aspartate symporter signature 317 343 2.7E-28 T 12-10-2018 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 PRINTS PR00173 Glutamate-aspartate symporter signature 352 371 2.7E-28 T 12-10-2018 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 320 343 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 SUPERFAMILY SSF118215 35 426 4.45E-105 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 Gene3D G3DSA:1.10.3860.10 26 439 1.6E-111 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 AFR_19960 79a23c102b9e27a9b7d1cd73355cc4e4 475 Pfam PF00375 Sodium:dicarboxylate symporter family 35 425 7.0E-101 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFR_15340 53c403dca6833aab21c785b67e3a9985 291 Gene3D G3DSA:1.10.260.40 6 86 1.5E-8 T 12-10-2018 AFR_15340 53c403dca6833aab21c785b67e3a9985 291 SUPERFAMILY SSF47413 32 83 2.96E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_15340 53c403dca6833aab21c785b67e3a9985 291 SMART SM00530 12 84 2.8E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_15340 53c403dca6833aab21c785b67e3a9985 291 Pfam PF13560 Helix-turn-helix domain 8 87 4.8E-17 T 12-10-2018 AFR_15340 53c403dca6833aab21c785b67e3a9985 291 Gene3D G3DSA:3.30.450.180 111 277 6.6E-8 T 12-10-2018 AFR_18755 91de84271b139d32c96fdb8b74d9bb79 374 Gene3D G3DSA:1.25.40.290 122 241 8.2E-34 T 12-10-2018 AFR_18755 91de84271b139d32c96fdb8b74d9bb79 374 Pfam PF08713 DNA alkylation repair enzyme 126 214 3.3E-5 T 12-10-2018 IPR014825 DNA alkylation repair enzyme AFR_18755 91de84271b139d32c96fdb8b74d9bb79 374 SUPERFAMILY SSF48371 78 241 2.02E-29 T 12-10-2018 IPR016024 Armadillo-type fold AFR_09615 2cac4696acbd547e6fed924755b22e51 192 SUPERFAMILY SSF46689 8 75 1.75E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_09615 2cac4696acbd547e6fed924755b22e51 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 6.9E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09615 2cac4696acbd547e6fed924755b22e51 192 Gene3D G3DSA:1.10.357.10 1 191 4.4E-44 T 12-10-2018 AFR_09615 2cac4696acbd547e6fed924755b22e51 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_09615 2cac4696acbd547e6fed924755b22e51 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28920 8804f86c9360924f9338f70306060047 910 SUPERFAMILY SSF48452 584 689 4.22E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_28920 8804f86c9360924f9338f70306060047 910 Pfam PF13191 AAA ATPase domain 2 158 4.2E-23 T 12-10-2018 AFR_28920 8804f86c9360924f9338f70306060047 910 SMART SM00421 842 899 1.1E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28920 8804f86c9360924f9338f70306060047 910 SUPERFAMILY SSF46894 835 903 2.45E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_28920 8804f86c9360924f9338f70306060047 910 Pfam PF00196 Bacterial regulatory proteins, luxR family 845 897 1.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28920 8804f86c9360924f9338f70306060047 910 Gene3D G3DSA:1.10.10.10 819 899 6.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28920 8804f86c9360924f9338f70306060047 910 SUPERFAMILY SSF52540 2 223 3.03E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28920 8804f86c9360924f9338f70306060047 910 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 875 6.8E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28920 8804f86c9360924f9338f70306060047 910 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 887 6.8E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28920 8804f86c9360924f9338f70306060047 910 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 845 859 6.8E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28920 8804f86c9360924f9338f70306060047 910 Gene3D G3DSA:1.25.40.10 564 808 8.3E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_28920 8804f86c9360924f9338f70306060047 910 Gene3D G3DSA:3.40.50.300 1 160 2.8E-5 T 12-10-2018 AFR_41095 901b17031dd0d079f2b8add97c02e454 372 Pfam PF00588 SpoU rRNA Methylase family 222 362 1.1E-34 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFR_41095 901b17031dd0d079f2b8add97c02e454 372 SUPERFAMILY SSF55315 122 203 3.41E-16 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFR_41095 901b17031dd0d079f2b8add97c02e454 372 Gene3D G3DSA:3.30.1330.30 121 202 4.2E-9 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFR_41095 901b17031dd0d079f2b8add97c02e454 372 Gene3D G3DSA:3.40.1280.10 204 370 2.6E-49 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFR_41095 901b17031dd0d079f2b8add97c02e454 372 SMART SM00967 130 206 2.1E-16 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFR_41095 901b17031dd0d079f2b8add97c02e454 372 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 129 369 3.1E-60 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 AFR_41095 901b17031dd0d079f2b8add97c02e454 372 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 130 205 2.0E-16 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFR_41095 901b17031dd0d079f2b8add97c02e454 372 SUPERFAMILY SSF75217 194 370 7.19E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFR_16500 bc6abbe658c28af38a848fd615f91442 495 Pfam PF08811 Protein of unknown function (DUF1800) 31 493 2.4E-120 T 12-10-2018 IPR014917 Protein of unknown function DUF1800 AFR_33770 6766a427342fe0fab89b89daded456ee 423 Gene3D G3DSA:3.40.50.150 149 415 3.3E-88 T 12-10-2018 AFR_33770 6766a427342fe0fab89b89daded456ee 423 SUPERFAMILY SSF53335 151 411 2.21E-72 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_33770 6766a427342fe0fab89b89daded456ee 423 PIRSF PIRSF003085 13 422 7.9E-108 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AFR_33770 6766a427342fe0fab89b89daded456ee 423 Pfam PF02353 Mycolic acid cyclopropane synthetase 140 406 5.5E-75 T 12-10-2018 AFR_02000 d6d3ab014b8e2e94148c6e7d25a94723 378 Pfam PF01494 FAD binding domain 5 281 8.7E-15 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_02000 d6d3ab014b8e2e94148c6e7d25a94723 378 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 5 295 8.3E-66 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AFR_02000 d6d3ab014b8e2e94148c6e7d25a94723 378 Gene3D G3DSA:3.50.50.60 3 343 1.6E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_02000 d6d3ab014b8e2e94148c6e7d25a94723 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 260 275 2.9E-14 T 12-10-2018 AFR_02000 d6d3ab014b8e2e94148c6e7d25a94723 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.9E-14 T 12-10-2018 AFR_02000 d6d3ab014b8e2e94148c6e7d25a94723 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 2.9E-14 T 12-10-2018 AFR_02000 d6d3ab014b8e2e94148c6e7d25a94723 378 SUPERFAMILY SSF51905 5 340 4.1E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_35755 dd49a5bc74dfbeee0e70f67ead1f1d59 309 SUPERFAMILY SSF51679 2 308 4.58E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_35755 dd49a5bc74dfbeee0e70f67ead1f1d59 309 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 3 223 2.3E-87 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c AFR_35755 dd49a5bc74dfbeee0e70f67ead1f1d59 309 Pfam PF00296 Luciferase-like monooxygenase 5 249 1.5E-52 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_35755 dd49a5bc74dfbeee0e70f67ead1f1d59 309 Gene3D G3DSA:3.20.20.30 1 308 3.1E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_13510 0c9fff6af769b7b68f2a8e5b09f6590e 100 Gene3D G3DSA:2.170.150.40 1 100 1.0E-23 T 12-10-2018 AFR_13510 0c9fff6af769b7b68f2a8e5b09f6590e 100 Pfam PF04248 Domain of unknown function (DUF427) 1 94 3.9E-25 T 12-10-2018 IPR007361 Domain of unknown function DUF427 AFR_06340 270867a09987c567acb28d41076fd6e0 140 Gene3D G3DSA:3.40.140.10 1 139 7.7E-34 T 12-10-2018 AFR_06340 270867a09987c567acb28d41076fd6e0 140 SUPERFAMILY SSF102712 2 129 5.1E-29 T 12-10-2018 AFR_06340 270867a09987c567acb28d41076fd6e0 140 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 121 4.5E-28 T 12-10-2018 IPR028090 JAB domain, prokaryotic AFR_06340 270867a09987c567acb28d41076fd6e0 140 SMART SM00232 1 131 1.1E-27 T 12-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 AFR_10440 ed3f7e09b7915adb4e126274bf19132b 106 Pfam PF11338 Protein of unknown function (DUF3140) 6 97 2.4E-40 T 12-10-2018 IPR021487 Protein of unknown function DUF3140 AFR_05950 c9692ab6cbafa19c038e75262233f8a0 208 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 35 5.1E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_05950 c9692ab6cbafa19c038e75262233f8a0 208 Pfam PF07963 Prokaryotic N-terminal methylation motif 12 34 1.1E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFR_28725 4a0a291baadc783a8c9b804daa2d019f 100 Pfam PF13601 Winged helix DNA-binding domain 14 91 8.5E-13 T 12-10-2018 IPR027395 Winged helix DNA-binding domain AFR_28725 4a0a291baadc783a8c9b804daa2d019f 100 Gene3D G3DSA:1.10.10.10 3 94 3.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28725 4a0a291baadc783a8c9b804daa2d019f 100 SUPERFAMILY SSF46785 7 92 7.05E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13550 6f3b411477d7a21886517a8b64f892b5 253 Pfam PF06723 MreB/Mbl protein 51 169 1.4E-9 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFR_13550 6f3b411477d7a21886517a8b64f892b5 253 Gene3D G3DSA:3.30.420.40 46 127 2.5E-14 T 12-10-2018 AFR_13550 6f3b411477d7a21886517a8b64f892b5 253 SUPERFAMILY SSF53067 133 249 1.09E-8 T 12-10-2018 AFR_13550 6f3b411477d7a21886517a8b64f892b5 253 Gene3D G3DSA:3.30.420.40 130 161 2.5E-14 T 12-10-2018 AFR_04600 c2961e4cd8260856873c430509383fea 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 147 18.958 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 AFR_04600 c2961e4cd8260856873c430509383fea 147 SUPERFAMILY SSF52080 8 145 2.35E-37 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily AFR_04600 c2961e4cd8260856873c430509383fea 147 Gene3D G3DSA:3.100.10.10 67 147 1.9E-20 T 12-10-2018 AFR_04600 c2961e4cd8260856873c430509383fea 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 141 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04600 c2961e4cd8260856873c430509383fea 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 145 2.0E-30 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P AFR_04600 c2961e4cd8260856873c430509383fea 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 144 3.0E-41 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 PRINTS PR00412 Epoxide hydrolase signature 93 106 1.7E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 PRINTS PR00412 Epoxide hydrolase signature 47 62 1.7E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 PRINTS PR00412 Epoxide hydrolase signature 212 228 1.7E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 PRINTS PR00412 Epoxide hydrolase signature 27 45 1.7E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 PRINTS PR00412 Epoxide hydrolase signature 246 268 1.7E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 Pfam PF00561 alpha/beta hydrolase fold 21 257 2.3E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 SUPERFAMILY SSF53474 3 267 2.23E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_08055 ee79bc1d7718d42e14fb959a9aa1fe83 271 Gene3D G3DSA:3.40.50.1820 1 267 4.4E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_40745 e9e962281f1269bcacbbed219b253b9a 222 Gene3D G3DSA:1.10.10.10 101 206 2.0E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40745 e9e962281f1269bcacbbed219b253b9a 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 129 203 1.2E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40745 e9e962281f1269bcacbbed219b253b9a 222 SMART SM00862 129 203 4.9E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40745 e9e962281f1269bcacbbed219b253b9a 222 Gene3D G3DSA:3.40.50.2300 1 100 1.5E-37 T 12-10-2018 AFR_40745 e9e962281f1269bcacbbed219b253b9a 222 SUPERFAMILY SSF46894 108 205 1.25E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_26530 53bdfb8fdea32c261d346cad3519235e 182 Gene3D G3DSA:3.40.50.2020 2 181 4.2E-50 T 12-10-2018 AFR_26530 53bdfb8fdea32c261d346cad3519235e 182 SUPERFAMILY SSF53271 8 177 2.49E-39 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_26530 53bdfb8fdea32c261d346cad3519235e 182 Pfam PF00156 Phosphoribosyl transferase domain 17 139 4.9E-19 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFR_26530 53bdfb8fdea32c261d346cad3519235e 182 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 13 175 5.7E-47 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 SUPERFAMILY SSF55973 245 393 2.79E-66 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 PIRSF PIRSF000497 1 396 1.2E-162 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 Gene3D G3DSA:3.30.300.10 102 386 1.6E-167 T 12-10-2018 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 394 1.0E-167 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 395 55.891 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 Gene3D G3DSA:3.30.300.10 11 282 1.6E-167 T 12-10-2018 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 Pfam PF02772 S-adenosylmethionine synthetase, central domain 125 243 4.9E-44 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 271 279 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 SUPERFAMILY SSF55973 3 109 6.28E-45 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 3.8E-40 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 245 383 3.4E-67 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 SUPERFAMILY SSF55973 122 243 1.45E-43 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFR_30575 31f6d89ddc74c39613ccbc2751f42f82 396 Gene3D G3DSA:3.30.300.10 5 245 1.6E-167 T 12-10-2018 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 Pfam PF01434 Peptidase family M41 452 651 1.8E-66 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 ProSitePatterns PS00674 AAA-protein family signature. 360 378 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 Gene3D G3DSA:3.40.50.300 209 391 1.4E-65 T 12-10-2018 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 30 686 34.426 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 Gene3D G3DSA:1.20.58.760 467 660 8.4E-66 T 12-10-2018 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 Gene3D G3DSA:1.10.8.60 392 466 8.6E-27 T 12-10-2018 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 SMART SM00382 252 392 6.9E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 167 650 1.6E-197 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 SUPERFAMILY SSF140990 471 652 5.36E-61 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 SUPERFAMILY SSF52540 215 461 9.06E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22615 905c6bd56f22f71d4901c69cfa59ea37 706 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 256 388 2.3E-43 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 Gene3D G3DSA:3.60.20.40 244 420 4.1E-41 T 12-10-2018 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 SUPERFAMILY SSF56235 10 420 5.21E-80 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 Pfam PF01019 Gamma-glutamyltranspeptidase 236 416 5.4E-33 T 12-10-2018 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 Pfam PF01019 Gamma-glutamyltranspeptidase 11 189 2.3E-35 T 12-10-2018 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 37 55 1.2E-15 T 12-10-2018 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 244 262 1.2E-15 T 12-10-2018 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 55 74 1.2E-15 T 12-10-2018 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 268 286 1.2E-15 T 12-10-2018 AFR_16955 d07fec1575093cfd40f7ffe54488a315 426 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 299 314 1.2E-15 T 12-10-2018 AFR_02045 a8ccc01f00172debddd7977c4857caca 179 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 177 2.1E-44 T 12-10-2018 IPR006286 Deglycase PfpI AFR_02045 a8ccc01f00172debddd7977c4857caca 179 Gene3D G3DSA:3.40.50.880 1 179 5.1E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_02045 a8ccc01f00172debddd7977c4857caca 179 SUPERFAMILY SSF52317 7 177 2.52E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_02045 a8ccc01f00172debddd7977c4857caca 179 Pfam PF01965 DJ-1/PfpI family 8 176 8.5E-52 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_27550 ae9490dd4675e1ae03b8052636ea20ac 279 SUPERFAMILY SSF56317 3 277 1.44E-78 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_27550 ae9490dd4675e1ae03b8052636ea20ac 279 Pfam PF00795 Carbon-nitrogen hydrolase 6 259 7.8E-63 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFR_27550 ae9490dd4675e1ae03b8052636ea20ac 279 Gene3D G3DSA:3.60.110.10 1 279 6.3E-97 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_25690 41b09e97816365a55287defe141f0716 361 SUPERFAMILY SSF52738 166 354 1.96E-55 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal AFR_25690 41b09e97816365a55287defe141f0716 361 Gene3D G3DSA:3.40.50.12740 2 166 1.8E-28 T 12-10-2018 AFR_25690 41b09e97816365a55287defe141f0716 361 SUPERFAMILY SSF52172 1 108 3.42E-25 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25690 41b09e97816365a55287defe141f0716 361 Gene3D G3DSA:3.40.50.180 167 360 2.4E-58 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal AFR_25690 41b09e97816365a55287defe141f0716 361 SMART SM00448 2 123 3.5E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25690 41b09e97816365a55287defe141f0716 361 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 355 32.16 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFR_25690 41b09e97816365a55287defe141f0716 361 PIRSF PIRSF000876 1 359 9.0E-102 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFR_25690 41b09e97816365a55287defe141f0716 361 Pfam PF00072 Response regulator receiver domain 4 107 2.0E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25690 41b09e97816365a55287defe141f0716 361 Pfam PF01339 CheB methylesterase 171 350 1.9E-51 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFR_33135 5e6847a6a6ed58bb4e0378c67f6198ed 322 SUPERFAMILY SSF161098 46 322 6.73E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_33135 5e6847a6a6ed58bb4e0378c67f6198ed 322 Gene3D G3DSA:1.10.3720.10 40 312 3.5E-57 T 12-10-2018 IPR035906 MetI-like superfamily AFR_33135 5e6847a6a6ed58bb4e0378c67f6198ed 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 309 1.7E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_25980 47a408a801b5eeb658f26576f76644ee 170 TIGRFAM TIGR04044 MSMEG_0572_fam: MSMEG_0572 family protein 14 170 3.5E-77 T 12-10-2018 IPR023847 Conserved hypothetical protein CHP04044, MSMEG0572 AFR_25980 47a408a801b5eeb658f26576f76644ee 170 Gene3D G3DSA:3.40.1260.10 37 154 4.5E-8 T 12-10-2018 IPR027396 DsrEFH-like AFR_25980 47a408a801b5eeb658f26576f76644ee 170 SUPERFAMILY SSF75169 43 157 5.49E-13 T 12-10-2018 IPR027396 DsrEFH-like AFR_25980 47a408a801b5eeb658f26576f76644ee 170 Pfam PF02635 DsrE/DsrF-like family 44 147 1.8E-4 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 SUPERFAMILY SSF88946 130 231 6.28E-24 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 Gene3D G3DSA:1.10.1740.10 125 213 1.3E-24 T 12-10-2018 AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 Pfam PF04542 Sigma-70 region 2 149 215 4.6E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 Pfam PF08281 Sigma-70, region 4 252 303 4.4E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 134 307 2.1E-62 T 12-10-2018 IPR014298 RNA polymerase sigma-X type AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 146 305 2.7E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 Gene3D G3DSA:1.10.10.10 227 310 6.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40205 552bf7c1988bc5eb2039d00ab0dd23ac 313 SUPERFAMILY SSF88659 239 307 9.53E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_16100 58ca7d8f35ed1252f31dc5b60084895b 121 Gene3D G3DSA:3.30.530.20 1 118 2.2E-24 T 12-10-2018 IPR023393 START-like domain superfamily AFR_16100 58ca7d8f35ed1252f31dc5b60084895b 121 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 2 115 2.4E-11 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_16100 58ca7d8f35ed1252f31dc5b60084895b 121 SUPERFAMILY SSF55961 2 115 3.23E-25 T 12-10-2018 AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 Pfam PF00586 AIR synthase related protein, N-terminal domain 31 140 1.2E-21 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 SUPERFAMILY SSF55326 4 140 1.74E-34 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 Gene3D G3DSA:3.30.1330.10 1 142 9.9E-45 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 311 26.775 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 SUPERFAMILY SSF56042 147 303 2.24E-32 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 7 311 7.8E-82 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 PIRSF PIRSF005303 1 311 5.5E-91 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 247 7.5E-7 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFR_36600 23292dd4079a307beca63b9dfd86d9a2 312 Gene3D G3DSA:3.90.650.10 149 311 3.2E-48 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 SMART SM00421 142 199 1.6E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 Pfam PF00072 Response regulator receiver domain 5 115 1.0E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 Gene3D G3DSA:3.40.50.12740 2 205 1.3E-70 T 12-10-2018 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 SUPERFAMILY SSF52172 1 133 2.28E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 2.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 2.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 2.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 SUPERFAMILY SSF46894 135 205 1.73E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 4.0E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31300 16c2f3dba010f3a2d203f1f5af98f08b 207 SMART SM00448 2 115 1.8E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13395 a2413caaa4ba7454e02787f086e1970e 122 Gene3D G3DSA:1.10.10.10 10 121 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13395 a2413caaa4ba7454e02787f086e1970e 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 3.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_13395 a2413caaa4ba7454e02787f086e1970e 122 SUPERFAMILY SSF46785 8 79 2.97E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13395 a2413caaa4ba7454e02787f086e1970e 122 SMART SM00345 17 76 2.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 Gene3D G3DSA:3.40.1190.10 112 337 4.9E-70 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 SUPERFAMILY SSF63418 13 112 4.32E-20 T 12-10-2018 IPR035911 MurE/MurF, N-terminal AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 Pfam PF08245 Mur ligase middle domain 122 317 1.8E-39 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 SUPERFAMILY SSF53244 338 497 1.31E-41 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 Pfam PF02875 Mur ligase family, glutamate ligase domain 338 424 4.4E-20 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 Gene3D G3DSA:3.90.190.20 340 499 4.2E-52 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 13 496 30.546 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 SUPERFAMILY SSF53623 112 336 3.14E-62 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 Gene3D G3DSA:3.40.1390.10 11 111 1.3E-29 T 12-10-2018 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 Pfam PF01225 Mur ligase family, catalytic domain 32 108 1.9E-10 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFR_09990 1ed52a0ff5b52b4db1392ada3b5e72c5 504 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 30 496 2.4E-133 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFR_14670 50d4843f4ac4033b3948697e5cb59e35 135 Pfam PF04237 YjbR 21 120 1.8E-9 T 12-10-2018 IPR007351 Uncharacterised protein YjbR AFR_14670 50d4843f4ac4033b3948697e5cb59e35 135 SUPERFAMILY SSF142906 13 132 7.59E-8 T 12-10-2018 IPR038056 YjbR-like superfamily AFR_29430 02e5ebc41e34f2d00859c77cccd0e316 278 Pfam PF09234 Domain of unknown function (DUF1963) 47 271 1.4E-13 T 12-10-2018 IPR015315 Protein of unknown function DUF1963 AFR_29430 02e5ebc41e34f2d00859c77cccd0e316 278 Gene3D G3DSA:2.30.320.10 14 273 1.6E-7 T 12-10-2018 IPR035948 YwqG-like superfamily AFR_29430 02e5ebc41e34f2d00859c77cccd0e316 278 SUPERFAMILY SSF103032 17 275 5.89E-14 T 12-10-2018 IPR035948 YwqG-like superfamily AFR_07105 a3244a9fbc745f78e243f7d1d6b68a3b 186 Pfam PF07098 Protein of unknown function (DUF1360) 63 164 1.0E-38 T 12-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 178 199 6.2E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 6.2E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 6.2E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 6.2E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 6.2E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 6.2E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 212 226 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 Pfam PF00459 Inositol monophosphatase family 32 253 4.7E-52 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 SUPERFAMILY SSF56655 3 259 5.5E-65 T 12-10-2018 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 92 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 Gene3D G3DSA:3.40.190.80 139 259 1.5E-26 T 12-10-2018 AFR_11375 894a02e6e8a2120b2b09bea3b7ecc59e 259 Gene3D G3DSA:3.30.540.10 1 138 1.1E-34 T 12-10-2018 AFR_31515 603d908c8e6d0c7fcb7e9855462c7e8d 382 SUPERFAMILY SSF51621 75 313 2.28E-19 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_31515 603d908c8e6d0c7fcb7e9855462c7e8d 382 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 89 266 5.7E-8 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 AFR_31515 603d908c8e6d0c7fcb7e9855462c7e8d 382 Gene3D G3DSA:3.20.20.60 56 318 5.3E-20 T 12-10-2018 AFR_03165 14417e0879c7feeb8fd0df3f41e5a2b6 318 SMART SM00418 244 318 0.0016 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_03165 14417e0879c7feeb8fd0df3f41e5a2b6 318 Gene3D G3DSA:1.10.10.10 238 313 1.3E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03165 14417e0879c7feeb8fd0df3f41e5a2b6 318 Pfam PF12840 Helix-turn-helix domain 250 300 8.7E-7 T 12-10-2018 AFR_03165 14417e0879c7feeb8fd0df3f41e5a2b6 318 SUPERFAMILY SSF46785 239 307 7.03E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_40270 d72afc4ec36165991f94cf6420d67490 227 SMART SM00862 149 225 2.2E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40270 d72afc4ec36165991f94cf6420d67490 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 1.8E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40270 d72afc4ec36165991f94cf6420d67490 227 Gene3D G3DSA:1.10.10.10 122 226 4.0E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40270 d72afc4ec36165991f94cf6420d67490 227 Pfam PF00072 Response regulator receiver domain 4 113 9.0E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40270 d72afc4ec36165991f94cf6420d67490 227 SMART SM00448 2 112 8.6E-45 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40270 d72afc4ec36165991f94cf6420d67490 227 Gene3D G3DSA:3.40.50.2300 1 121 8.6E-38 T 12-10-2018 AFR_40270 d72afc4ec36165991f94cf6420d67490 227 SUPERFAMILY SSF46894 126 226 7.37E-32 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_40270 d72afc4ec36165991f94cf6420d67490 227 SUPERFAMILY SSF52172 3 123 1.2E-41 T 12-10-2018 IPR011006 CheY-like superfamily AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 SMART SM01217 584 654 1.8E-29 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 Gene3D G3DSA:2.60.40.10 554 670 5.2E-37 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 Pfam PF14310 Fibronectin type III-like domain 584 654 1.1E-23 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 317 551 1.1E-53 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 Gene3D G3DSA:3.20.20.300 3 288 1.4E-109 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 Gene3D G3DSA:3.40.50.1700 301 552 1.4E-71 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 116 132 2.4E-37 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 147 163 2.4E-37 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 34 50 2.4E-37 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 70 89 2.4E-37 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 217 235 2.4E-37 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 SUPERFAMILY SSF51445 5 315 4.0E-94 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 26 285 3.0E-54 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 217 234 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AFR_11225 249d3a1400bc9ff45930585acb9cdc15 746 SUPERFAMILY SSF52279 317 554 4.32E-53 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_05110 d5ab409533f70f68a86de607cbd4ec6e 205 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 8 193 26.996 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFR_05110 d5ab409533f70f68a86de607cbd4ec6e 205 Pfam PF00551 Formyl transferase 8 185 5.1E-47 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_05110 d5ab409533f70f68a86de607cbd4ec6e 205 SUPERFAMILY SSF53328 8 202 6.41E-54 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_05110 d5ab409533f70f68a86de607cbd4ec6e 205 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 139 162 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_05110 d5ab409533f70f68a86de607cbd4ec6e 205 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 7 193 1.4E-62 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFR_05110 d5ab409533f70f68a86de607cbd4ec6e 205 Gene3D G3DSA:3.40.50.170 1 205 4.7E-68 T 12-10-2018 AFR_08445 3dbb3bf5fbe3a134bdf420cf633ffa3d 565 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 36 371 4.7E-83 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_08445 3dbb3bf5fbe3a134bdf420cf633ffa3d 565 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 294 311 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AFR_08445 3dbb3bf5fbe3a134bdf420cf633ffa3d 565 SUPERFAMILY SSF51445 24 405 4.11E-89 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_08445 3dbb3bf5fbe3a134bdf420cf633ffa3d 565 Gene3D G3DSA:3.20.20.300 22 388 6.0E-109 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_08445 3dbb3bf5fbe3a134bdf420cf633ffa3d 565 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 409 555 3.7E-13 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AFR_08445 3dbb3bf5fbe3a134bdf420cf633ffa3d 565 SUPERFAMILY SSF52279 409 555 6.67E-15 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_08445 3dbb3bf5fbe3a134bdf420cf633ffa3d 565 Gene3D G3DSA:3.40.50.1700 392 565 1.5E-30 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_19000 21a268930fe691b1878c45cff66870ab 399 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 254 368 3.5E-17 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFR_19000 21a268930fe691b1878c45cff66870ab 399 SMART SM00833 252 368 2.8E-30 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFR_19000 21a268930fe691b1878c45cff66870ab 399 SUPERFAMILY SSF90002 254 368 2.35E-11 T 12-10-2018 AFR_19000 21a268930fe691b1878c45cff66870ab 399 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 72 184 3.8E-9 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFR_19000 21a268930fe691b1878c45cff66870ab 399 Gene3D G3DSA:3.40.50.300 20 215 1.5E-10 T 12-10-2018 AFR_03450 b20025bec6a33783c43822a4336d649f 179 SUPERFAMILY SSF46785 7 105 1.87E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_03450 b20025bec6a33783c43822a4336d649f 179 Gene3D G3DSA:1.10.10.10 8 116 3.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03450 b20025bec6a33783c43822a4336d649f 179 Pfam PF12840 Helix-turn-helix domain 11 67 5.8E-11 T 12-10-2018 AFR_03450 b20025bec6a33783c43822a4336d649f 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 6.5E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_03450 b20025bec6a33783c43822a4336d649f 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 6.5E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_03450 b20025bec6a33783c43822a4336d649f 179 SMART SM00418 11 112 5.4E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_02285 dd033bc3a4dd0bfb13f754d1283c6037 261 SMART SM00382 67 254 2.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_02285 dd033bc3a4dd0bfb13f754d1283c6037 261 SUPERFAMILY SSF52540 53 256 3.34E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02285 dd033bc3a4dd0bfb13f754d1283c6037 261 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_02285 dd033bc3a4dd0bfb13f754d1283c6037 261 Pfam PF00005 ABC transporter 59 192 2.2E-15 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_02285 dd033bc3a4dd0bfb13f754d1283c6037 261 Gene3D G3DSA:3.40.50.300 39 261 1.3E-39 T 12-10-2018 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 PRINTS PR01217 Proline rich extensin signature 331 347 4.9E-11 T 12-10-2018 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 PRINTS PR01217 Proline rich extensin signature 420 437 4.9E-11 T 12-10-2018 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 PRINTS PR01217 Proline rich extensin signature 377 398 4.9E-11 T 12-10-2018 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 PRINTS PR01217 Proline rich extensin signature 402 418 4.9E-11 T 12-10-2018 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 Gene3D G3DSA:1.10.510.10 92 274 3.1E-43 T 12-10-2018 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 PIRSF PIRSF000654 22 272 8.9E-19 T 12-10-2018 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 SUPERFAMILY SSF56112 5 409 1.82E-64 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 Pfam PF00069 Protein kinase domain 8 263 1.2E-40 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 SMART SM00220 8 270 4.9E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_28780 c7de2c37766f9b04d5008ff3638dcc00 462 Gene3D G3DSA:3.30.200.20 1 91 2.9E-25 T 12-10-2018 AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 Pfam PF13377 Periplasmic binding protein-like domain 176 331 2.2E-31 T 12-10-2018 AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 SUPERFAMILY SSF53822 73 335 6.52E-51 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 1.3E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 Gene3D G3DSA:3.40.50.2300 167 284 1.2E-56 T 12-10-2018 AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 SMART SM00354 11 81 2.0E-22 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 SUPERFAMILY SSF47413 10 68 1.69E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 Gene3D G3DSA:1.10.260.40 3 68 2.3E-22 T 12-10-2018 AFR_21665 321ba30ccc39a1f0fe46d3fd160e364f 340 Gene3D G3DSA:3.40.50.2300 73 304 1.2E-56 T 12-10-2018 AFR_35715 0cac021378272658d87ca31420f1d996 443 Pfam PF01595 Domain of unknown function DUF21 8 199 3.4E-36 T 12-10-2018 IPR002550 CNNM, transmembrane domain AFR_35715 0cac021378272658d87ca31420f1d996 443 SUPERFAMILY SSF54631 207 339 5.05E-24 T 12-10-2018 AFR_35715 0cac021378272658d87ca31420f1d996 443 SUPERFAMILY SSF56176 353 431 2.34E-20 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_35715 0cac021378272658d87ca31420f1d996 443 SMART SM01091 352 432 2.0E-24 T 12-10-2018 IPR005170 Transporter-associated domain AFR_35715 0cac021378272658d87ca31420f1d996 443 Pfam PF00571 CBS domain 218 271 9.1E-5 T 12-10-2018 IPR000644 CBS domain AFR_35715 0cac021378272658d87ca31420f1d996 443 Pfam PF00571 CBS domain 286 337 4.8E-6 T 12-10-2018 IPR000644 CBS domain AFR_35715 0cac021378272658d87ca31420f1d996 443 Pfam PF03471 Transporter associated domain 353 429 2.3E-20 T 12-10-2018 IPR005170 Transporter-associated domain AFR_35715 0cac021378272658d87ca31420f1d996 443 Gene3D G3DSA:3.10.580.10 201 347 6.4E-39 T 12-10-2018 AFR_35715 0cac021378272658d87ca31420f1d996 443 Gene3D G3DSA:3.30.465.10 352 431 4.5E-21 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_02785 dc028c6232d104341fdf0badd948d8c2 57 Gene3D G3DSA:1.10.1470.10 3 56 2.3E-7 T 12-10-2018 IPR036629 YjbJ superfamily AFR_02785 dc028c6232d104341fdf0badd948d8c2 57 Pfam PF05532 CsbD-like 5 56 1.2E-18 T 12-10-2018 IPR008462 CsbD-like domain AFR_02785 dc028c6232d104341fdf0badd948d8c2 57 SUPERFAMILY SSF69047 4 56 2.22E-9 T 12-10-2018 IPR036629 YjbJ superfamily AFR_23980 c8d9c64f1fa26d41d8e9e72e41b61217 808 SUPERFAMILY SSF53756 13 806 5.57E-293 T 12-10-2018 AFR_23980 c8d9c64f1fa26d41d8e9e72e41b61217 808 Gene3D G3DSA:3.40.50.2000 25 803 0.0 T 12-10-2018 AFR_23980 c8d9c64f1fa26d41d8e9e72e41b61217 808 Pfam PF00343 Carbohydrate phosphorylase 101 801 1.2E-292 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFR_23980 c8d9c64f1fa26d41d8e9e72e41b61217 808 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 15 801 0.0 T 12-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFR_23980 c8d9c64f1fa26d41d8e9e72e41b61217 808 Gene3D G3DSA:3.40.50.2000 468 786 0.0 T 12-10-2018 AFR_23980 c8d9c64f1fa26d41d8e9e72e41b61217 808 PIRSF PIRSF000460 4 807 1.1E-216 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFR_23980 c8d9c64f1fa26d41d8e9e72e41b61217 808 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 655 667 - T 12-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFR_42005 ae995f1d8f80634a2e87b5e0b84f9289 582 SUPERFAMILY SSF50370 482 567 1.69E-6 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_42005 ae995f1d8f80634a2e87b5e0b84f9289 582 Gene3D G3DSA:2.80.10.50 224 377 6.6E-9 T 12-10-2018 AFR_42005 ae995f1d8f80634a2e87b5e0b84f9289 582 Gene3D G3DSA:2.80.10.50 395 574 1.4E-11 T 12-10-2018 AFR_42005 ae995f1d8f80634a2e87b5e0b84f9289 582 SUPERFAMILY SSF50370 220 368 6.61E-8 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_23805 2311f864f125257806ea6937a8df0e42 281 SUPERFAMILY SSF51735 2 263 3.72E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23805 2311f864f125257806ea6937a8df0e42 281 Gene3D G3DSA:3.40.50.720 3 269 1.6E-79 T 12-10-2018 AFR_23805 2311f864f125257806ea6937a8df0e42 281 Gene3D G3DSA:3.90.25.10 139 270 1.6E-79 T 12-10-2018 AFR_23805 2311f864f125257806ea6937a8df0e42 281 Pfam PF13460 NAD(P)H-binding 6 185 1.2E-19 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_07295 e34e1ad6cc9a301c630771b47fee3106 202 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 70 148 9.6E-6 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 AFR_07295 e34e1ad6cc9a301c630771b47fee3106 202 Gene3D G3DSA:3.40.50.300 3 185 4.0E-28 T 12-10-2018 AFR_07295 e34e1ad6cc9a301c630771b47fee3106 202 SUPERFAMILY SSF52540 21 172 2.13E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26380 3956bc34de2aa334d179008ca3e46750 163 SMART SM00418 10 89 7.5E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26380 3956bc34de2aa334d179008ca3e46750 163 Pfam PF12840 Helix-turn-helix domain 11 67 1.8E-14 T 12-10-2018 AFR_26380 3956bc34de2aa334d179008ca3e46750 163 SUPERFAMILY SSF46785 10 89 1.51E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26380 3956bc34de2aa334d179008ca3e46750 163 Gene3D G3DSA:1.10.10.10 2 82 1.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19720 aa89484330370c6b5e443391b4202c29 217 Pfam PF01872 RibD C-terminal domain 1 206 2.8E-41 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_19720 aa89484330370c6b5e443391b4202c29 217 SUPERFAMILY SSF53597 1 210 6.02E-44 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_19720 aa89484330370c6b5e443391b4202c29 217 Gene3D G3DSA:3.40.430.10 1 211 5.0E-52 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_03560 249797c9d375deea24d862e8c8728884 378 Gene3D G3DSA:3.40.50.720 1 127 3.6E-34 T 12-10-2018 AFR_03560 249797c9d375deea24d862e8c8728884 378 SUPERFAMILY SSF55347 132 309 1.55E-33 T 12-10-2018 AFR_03560 249797c9d375deea24d862e8c8728884 378 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 221 9.1E-11 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_03560 249797c9d375deea24d862e8c8728884 378 SUPERFAMILY SSF51735 1 155 4.34E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03560 249797c9d375deea24d862e8c8728884 378 Gene3D G3DSA:3.30.360.10 128 377 1.2E-59 T 12-10-2018 AFR_03560 249797c9d375deea24d862e8c8728884 378 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 126 1.6E-22 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_32725 fb8acffba6525d3ff51121b19513f7d7 389 Pfam PF13454 FAD-NAD(P)-binding 2 111 1.7E-23 T 12-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain AFR_32725 fb8acffba6525d3ff51121b19513f7d7 389 SUPERFAMILY SSF51905 1 170 7.51E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_32725 fb8acffba6525d3ff51121b19513f7d7 389 Gene3D G3DSA:3.50.50.60 29 211 6.7E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25270 59e8229330cafe3509b00500d22b351b 439 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 145 230 2.3E-19 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_25270 59e8229330cafe3509b00500d22b351b 439 SUPERFAMILY SSF51735 3 164 1.97E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_25270 59e8229330cafe3509b00500d22b351b 439 SUPERFAMILY SSF55347 138 332 1.64E-29 T 12-10-2018 AFR_25270 59e8229330cafe3509b00500d22b351b 439 Gene3D G3DSA:3.40.50.720 2 143 4.5E-27 T 12-10-2018 AFR_25270 59e8229330cafe3509b00500d22b351b 439 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 133 4.2E-18 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_10610 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_10610 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_10610 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_10610 4d71afd76562303bb215dedd7a6c3b4b 89 PIRSF PIRSF004669 1 89 5.6E-31 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_10610 4d71afd76562303bb215dedd7a6c3b4b 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 4.4E-27 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 AFR_10610 4d71afd76562303bb215dedd7a6c3b4b 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 7.6E-27 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_19185 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_19185 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_19185 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_19185 4d71afd76562303bb215dedd7a6c3b4b 89 PIRSF PIRSF004669 1 89 5.6E-31 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_19185 4d71afd76562303bb215dedd7a6c3b4b 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 4.4E-27 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 AFR_19185 4d71afd76562303bb215dedd7a6c3b4b 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 7.6E-27 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_31095 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_31095 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_31095 4d71afd76562303bb215dedd7a6c3b4b 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.9E-17 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_31095 4d71afd76562303bb215dedd7a6c3b4b 89 PIRSF PIRSF004669 1 89 5.6E-31 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_31095 4d71afd76562303bb215dedd7a6c3b4b 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 4.4E-27 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 AFR_31095 4d71afd76562303bb215dedd7a6c3b4b 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 7.6E-27 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFR_29295 68c1ed7e83520da109c268888f1efae1 468 Gene3D G3DSA:3.90.1300.10 1 467 7.0E-136 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_29295 68c1ed7e83520da109c268888f1efae1 468 Pfam PF01425 Amidase 26 449 1.5E-101 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_29295 68c1ed7e83520da109c268888f1efae1 468 SUPERFAMILY SSF75304 3 457 1.31E-125 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_29295 68c1ed7e83520da109c268888f1efae1 468 ProSitePatterns PS00571 Amidases signature. 153 184 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFR_22630 498190baea5a87434cb5e76ee2958fd0 255 Gene3D G3DSA:3.40.50.300 3 234 5.0E-61 T 12-10-2018 AFR_22630 498190baea5a87434cb5e76ee2958fd0 255 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_22630 498190baea5a87434cb5e76ee2958fd0 255 Pfam PF00005 ABC transporter 23 164 2.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_22630 498190baea5a87434cb5e76ee2958fd0 255 SUPERFAMILY SSF52540 7 225 5.01E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22630 498190baea5a87434cb5e76ee2958fd0 255 SMART SM00382 32 221 8.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_42180 4c97144ed403b0f1be91bdc94b0ef0d8 257 Pfam PF02517 CAAX protease self-immunity 151 240 1.5E-13 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFR_33375 2b4f36850afea56516099cf658bf96e6 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 47 5.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33375 2b4f36850afea56516099cf658bf96e6 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 3 16 5.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33375 2b4f36850afea56516099cf658bf96e6 174 Gene3D G3DSA:1.10.10.60 1 41 3.6E-19 T 12-10-2018 AFR_33375 2b4f36850afea56516099cf658bf96e6 174 Gene3D G3DSA:1.10.357.10 42 174 1.1E-31 T 12-10-2018 AFR_33375 2b4f36850afea56516099cf658bf96e6 174 Pfam PF16859 Bacterial transcriptional repressor C-terminal 60 167 7.5E-25 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_33375 2b4f36850afea56516099cf658bf96e6 174 SUPERFAMILY SSF48498 64 172 6.23E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_33375 2b4f36850afea56516099cf658bf96e6 174 Pfam PF00440 Bacterial regulatory proteins, tetR family 3 47 2.2E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33375 2b4f36850afea56516099cf658bf96e6 174 SUPERFAMILY SSF46689 2 56 9.98E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_31195 6b879400fd52035909bc9c623943cbd3 339 Pfam PF00962 Adenosine/AMP deaminase 11 329 1.1E-83 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 AFR_31195 6b879400fd52035909bc9c623943cbd3 339 SUPERFAMILY SSF51556 6 335 1.7E-78 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_31195 6b879400fd52035909bc9c623943cbd3 339 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 332 6.4E-84 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 AFR_31195 6b879400fd52035909bc9c623943cbd3 339 Gene3D G3DSA:3.20.20.140 1 339 6.6E-98 T 12-10-2018 AFR_27680 b6f11710f4f0f6f8475cf8d888299ac4 353 Gene3D G3DSA:2.40.420.20 294 350 1.4E-10 T 12-10-2018 AFR_27680 b6f11710f4f0f6f8475cf8d888299ac4 353 Gene3D G3DSA:2.40.50.100 173 211 1.4E-10 T 12-10-2018 AFR_27680 b6f11710f4f0f6f8475cf8d888299ac4 353 SUPERFAMILY SSF47090 99 176 2.88E-7 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_27680 b6f11710f4f0f6f8475cf8d888299ac4 353 Gene3D G3DSA:2.40.30.170 212 293 1.4E-10 T 12-10-2018 AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 61 292 3.3E-64 T 12-10-2018 AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 189 217 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 221 8.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 53 70 8.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 192 8.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 240 8.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 8.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 257 277 8.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 SUPERFAMILY SSF51735 51 292 3.64E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 Gene3D G3DSA:3.40.50.720 6 294 1.8E-89 T 12-10-2018 AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 1.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 190 1.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_07510 8e6eaad27efbb6c157cee5d9aa454f78 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 202 221 1.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 SUPERFAMILY SSF52540 14 421 1.11E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 Gene3D G3DSA:3.40.50.300 14 440 1.6E-155 T 12-10-2018 AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 Pfam PF00005 ABC transporter 470 672 1.8E-11 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 SUPERFAMILY SSF52540 463 725 1.2E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 Gene3D G3DSA:1.20.1580.10 546 584 4.9E-102 T 12-10-2018 AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 Gene3D G3DSA:3.40.50.300 464 748 4.9E-102 T 12-10-2018 AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 Gene3D G3DSA:1.20.1580.10 100 339 1.6E-155 T 12-10-2018 AFR_21105 4cf39dc7b83ff56f602ffbca91ef920f 754 Gene3D G3DSA:1.10.8.280 153 261 1.6E-155 T 12-10-2018 AFR_25175 936c9e40d304edc5c476a432d55f0b0e 643 Pfam PF03572 Peptidase family S41 320 535 2.7E-16 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFR_25175 936c9e40d304edc5c476a432d55f0b0e 643 SUPERFAMILY SSF52096 68 556 1.39E-26 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_25175 936c9e40d304edc5c476a432d55f0b0e 643 Gene3D G3DSA:3.90.226.10 295 561 1.1E-22 T 12-10-2018 AFR_32425 fb6be0f48b52e5d6b73c861ae3cffdb2 136 Pfam PF13396 Phospholipase_D-nuclease N-terminal 14 59 1.1E-9 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal AFR_17335 28aa81dc114bd295257985d1632a658c 218 SUPERFAMILY SSF52172 1 118 1.85E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_17335 28aa81dc114bd295257985d1632a658c 218 SMART SM00448 1 112 3.0E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17335 28aa81dc114bd295257985d1632a658c 218 Pfam PF00072 Response regulator receiver domain 3 113 4.9E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17335 28aa81dc114bd295257985d1632a658c 218 SMART SM00862 145 217 5.0E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_17335 28aa81dc114bd295257985d1632a658c 218 Gene3D G3DSA:1.10.10.10 119 218 1.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17335 28aa81dc114bd295257985d1632a658c 218 SUPERFAMILY SSF46894 119 217 3.97E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_17335 28aa81dc114bd295257985d1632a658c 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 2.6E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_17335 28aa81dc114bd295257985d1632a658c 218 Gene3D G3DSA:3.40.50.2300 1 118 5.8E-31 T 12-10-2018 AFR_33610 a29796ccb1e8e1388e7fc8a3af771aa6 271 Gene3D G3DSA:3.40.50.720 1 155 4.7E-27 T 12-10-2018 AFR_33610 a29796ccb1e8e1388e7fc8a3af771aa6 271 Gene3D G3DSA:1.10.1040.10 157 263 3.7E-10 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_33610 a29796ccb1e8e1388e7fc8a3af771aa6 271 Pfam PF09130 Domain of unknown function (DUF1932) 176 241 2.5E-14 T 12-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal AFR_33610 a29796ccb1e8e1388e7fc8a3af771aa6 271 SUPERFAMILY SSF51735 2 133 1.09E-15 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_33610 a29796ccb1e8e1388e7fc8a3af771aa6 271 SUPERFAMILY SSF48179 149 245 1.53E-21 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_33610 a29796ccb1e8e1388e7fc8a3af771aa6 271 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 124 9.6E-5 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Gene3D G3DSA:3.40.50.300 208 340 3.8E-39 T 12-10-2018 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Pfam PF16124 RecQ zinc-binding 343 405 9.1E-17 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain AFR_19690 19bea11a96041a6ed579767c6220efb8 613 SMART SM00341 540 613 1.3E-9 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Gene3D G3DSA:1.10.150.80 544 612 8.9E-23 T 12-10-2018 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 13 611 5.1E-232 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 SUPERFAMILY SSF47819 538 612 2.18E-20 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Gene3D G3DSA:3.40.50.300 2 207 4.3E-78 T 12-10-2018 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Pfam PF00270 DEAD/DEAH box helicase 29 184 2.1E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Pfam PF09382 RQC domain 407 521 9.6E-35 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 SMART SM00490 250 331 3.3E-23 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_19690 19bea11a96041a6ed579767c6220efb8 613 SMART SM00487 21 217 8.8E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_19690 19bea11a96041a6ed579767c6220efb8 613 SUPERFAMILY SSF52540 12 195 6.82E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Pfam PF00271 Helicase conserved C-terminal domain 225 330 1.2E-15 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Pfam PF00570 HRDC domain 546 609 4.1E-21 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 Gene3D G3DSA:1.10.10.10 341 528 6.1E-48 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19690 19bea11a96041a6ed579767c6220efb8 613 SUPERFAMILY SSF52540 203 460 2.92E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19690 19bea11a96041a6ed579767c6220efb8 613 SMART SM00956 412 518 5.6E-44 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AFR_19690 19bea11a96041a6ed579767c6220efb8 613 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 14 467 1.3E-149 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 AFR_01770 ab605904a260cbb841f168932b15d626 108 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 1.3E-14 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_01770 ab605904a260cbb841f168932b15d626 108 Gene3D G3DSA:1.10.287.1060 3 100 1.8E-18 T 12-10-2018 AFR_01770 ab605904a260cbb841f168932b15d626 108 Pfam PF06013 Proteins of 100 residues with WXG 4 87 6.1E-14 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_01770 ab605904a260cbb841f168932b15d626 108 SUPERFAMILY SSF140453 6 95 1.31E-17 T 12-10-2018 IPR036689 ESAT-6-like superfamily AFR_06065 ab72d03be4b902457fff1fedeb6d9533 68 TIGRFAM TIGR04268 FxSxx-COOH: FXSXX-COOH protein 19 68 8.0E-11 T 12-10-2018 IPR026334 FXSXX-COOH protein AFR_38550 8d21d7b6b46c5e7232bc684bd2c3d1c4 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 2.1E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_38550 8d21d7b6b46c5e7232bc684bd2c3d1c4 137 Gene3D G3DSA:3.10.180.10 2 137 4.5E-39 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_38550 8d21d7b6b46c5e7232bc684bd2c3d1c4 137 SUPERFAMILY SSF54593 5 134 5.24E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_32120 b9bdff5524559215f569353d7e827f8c 352 SMART SM00354 14 84 2.1E-24 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 Gene3D G3DSA:3.40.50.2300 185 312 3.5E-65 T 12-10-2018 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 Gene3D G3DSA:3.40.50.2300 69 329 3.5E-65 T 12-10-2018 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 16 61 3.7E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 SUPERFAMILY SSF47413 14 72 2.63E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 SUPERFAMILY SSF53822 95 351 9.03E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_32120 b9bdff5524559215f569353d7e827f8c 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 17 35 - T 12-10-2018 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 Gene3D G3DSA:1.10.260.40 15 68 6.0E-20 T 12-10-2018 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 Pfam PF13377 Periplasmic binding protein-like domain 193 351 1.6E-34 T 12-10-2018 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 1.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_32120 b9bdff5524559215f569353d7e827f8c 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 26 36 1.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_27925 a58590558a32fee8df2e888e46a79b66 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 260 4.0E-52 T 12-10-2018 AFR_27925 a58590558a32fee8df2e888e46a79b66 264 SUPERFAMILY SSF51735 17 260 1.89E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 5.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 5.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 5.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 5.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 5.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_27925 a58590558a32fee8df2e888e46a79b66 264 Gene3D G3DSA:3.40.50.720 10 261 1.2E-79 T 12-10-2018 AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 4.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 4.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27925 a58590558a32fee8df2e888e46a79b66 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 4.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10175 a9a889eaddaf3d5a999951104b867d5e 231 Gene3D G3DSA:3.20.20.370 17 231 4.5E-57 T 12-10-2018 AFR_10175 a9a889eaddaf3d5a999951104b867d5e 231 Pfam PF01522 Polysaccharide deacetylase 38 158 1.2E-31 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_10175 a9a889eaddaf3d5a999951104b867d5e 231 SUPERFAMILY SSF88713 32 230 3.11E-54 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_18155 2723c1739224fb3d607f84a112a4ba03 522 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 115 242 1.2E-8 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Pfam PF07517 SecA DEAD-like domain 40 377 1.7E-85 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 ProSitePatterns PS01312 SecA family signature. 477 492 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 SUPERFAMILY SSF81767 223 344 7.19E-29 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Gene3D G3DSA:3.40.50.300 49 392 2.4E-124 T 12-10-2018 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 PRINTS PR00906 SecA protein signature 58 82 1.6E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 PRINTS PR00906 SecA protein signature 353 370 1.6E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 PRINTS PR00906 SecA protein signature 96 110 1.6E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 PRINTS PR00906 SecA protein signature 166 186 1.6E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 PRINTS PR00906 SecA protein signature 390 403 1.6E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 PRINTS PR00906 SecA protein signature 316 338 1.6E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 8 758 0.0 T 12-10-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Gene3D G3DSA:3.40.50.300 394 497 1.6E-33 T 12-10-2018 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Gene3D G3DSA:3.40.50.300 498 574 1.9E-22 T 12-10-2018 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Hamap MF_01382 Protein translocase subunit SecA [secA]. 6 717 15.359 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 SMART SM00958 224 335 5.8E-33 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Pfam PF01043 SecA preprotein cross-linking domain 234 335 1.4E-23 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 SUPERFAMILY SSF81886 575 715 9.81E-27 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 SUPERFAMILY SSF52540 394 558 1.53E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Pfam PF07516 SecA Wing and Scaffold domain 632 711 1.4E-14 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Gene3D G3DSA:1.10.3060.10 575 720 6.3E-25 T 12-10-2018 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 SUPERFAMILY SSF52540 28 391 1.86E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 SMART SM00957 7 379 1.0E-155 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFR_26775 72bc7692d459984a92fbd17840e8f2bd 762 Gene3D G3DSA:3.90.1440.10 225 345 2.4E-124 T 12-10-2018 AFR_14165 4aac2682f26b206cb29ee24d2e557e46 143 SUPERFAMILY SSF55729 13 134 3.95E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_14165 4aac2682f26b206cb29ee24d2e557e46 143 Pfam PF00583 Acetyltransferase (GNAT) family 31 131 9.5E-18 T 12-10-2018 IPR000182 GNAT domain AFR_14165 4aac2682f26b206cb29ee24d2e557e46 143 Gene3D G3DSA:3.40.630.30 4 138 4.5E-27 T 12-10-2018 AFR_32680 337aa2bd3eee46fa99366ce0c20c4aac 258 SMART SM00849 10 206 0.0062 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_32680 337aa2bd3eee46fa99366ce0c20c4aac 258 Gene3D G3DSA:3.60.15.10 2 257 9.4E-50 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_32680 337aa2bd3eee46fa99366ce0c20c4aac 258 SUPERFAMILY SSF56281 6 213 3.5E-26 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_32680 337aa2bd3eee46fa99366ce0c20c4aac 258 Pfam PF12706 Beta-lactamase superfamily domain 23 207 4.8E-30 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_02770 d554fc7f089db6bb97e51735cb090666 214 Gene3D G3DSA:3.40.50.12740 1 209 2.9E-47 T 12-10-2018 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 Pfam PF00072 Response regulator receiver domain 3 112 6.0E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 SMART SM00421 148 210 8.5E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 SUPERFAMILY SSF46894 132 203 1.29E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 SMART SM00448 1 120 6.0E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_02770 d554fc7f089db6bb97e51735cb090666 214 SUPERFAMILY SSF52172 1 136 9.68E-19 T 12-10-2018 IPR011006 CheY-like superfamily AFR_02770 d554fc7f089db6bb97e51735cb090666 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 198 7.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31080 e69006278320569a1bacfe5f6826f06d 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 239 1.7E-96 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_31080 e69006278320569a1bacfe5f6826f06d 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 241 34.572 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_31080 e69006278320569a1bacfe5f6826f06d 251 Pfam PF01709 Transcriptional regulator 5 239 2.1E-88 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_31080 e69006278320569a1bacfe5f6826f06d 251 SUPERFAMILY SSF75625 3 247 1.2E-88 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_31080 e69006278320569a1bacfe5f6826f06d 251 Gene3D G3DSA:3.30.70.980 135 205 1.1E-52 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_31080 e69006278320569a1bacfe5f6826f06d 251 Gene3D G3DSA:3.30.70.980 86 238 1.1E-52 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_31080 e69006278320569a1bacfe5f6826f06d 251 Gene3D G3DSA:1.10.10.200 1 80 2.5E-30 T 12-10-2018 IPR017856 Integrase-like, N-terminal AFR_11530 8b3df18d47acd98f7f57c272fe436337 229 SUPERFAMILY SSF101874 20 221 5.75E-39 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily AFR_11530 8b3df18d47acd98f7f57c272fe436337 229 SMART SM00867 19 219 5.3E-46 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFR_11530 8b3df18d47acd98f7f57c272fe436337 229 Pfam PF04264 YceI-like domain 20 218 4.2E-38 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFR_13480 a1e8a1dfd46122ec0b10c798f190491a 60 Pfam PF00248 Aldo/keto reductase family 1 57 9.4E-13 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_13480 a1e8a1dfd46122ec0b10c798f190491a 60 SUPERFAMILY SSF51430 1 57 2.23E-16 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_13480 a1e8a1dfd46122ec0b10c798f190491a 60 Gene3D G3DSA:3.20.20.100 1 60 6.0E-18 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_00975 c861b03e5b3a5e74fbb33ad953535fb8 354 PIRSF PIRSF035875 41 340 4.9E-85 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_00975 c861b03e5b3a5e74fbb33ad953535fb8 354 Pfam PF03631 Virulence factor BrkB 64 319 5.6E-67 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_00975 c861b03e5b3a5e74fbb33ad953535fb8 354 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 56 317 2.6E-36 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_22465 8eacd1d1ce780564b240acc98b9d796e 265 Gene3D G3DSA:3.40.50.150 19 260 2.3E-32 T 12-10-2018 AFR_22465 8eacd1d1ce780564b240acc98b9d796e 265 Pfam PF08241 Methyltransferase domain 39 130 7.1E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_22465 8eacd1d1ce780564b240acc98b9d796e 265 SUPERFAMILY SSF53335 11 209 2.13E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_28110 ebf81a74abc0136d8f898f46e8b029db 845 Gene3D G3DSA:3.40.630.10 107 315 5.4E-33 T 12-10-2018 AFR_28110 ebf81a74abc0136d8f898f46e8b029db 845 SUPERFAMILY SSF53187 101 361 1.36E-37 T 12-10-2018 AFR_28110 ebf81a74abc0136d8f898f46e8b029db 845 SMART SM00631 102 383 4.7E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_28110 ebf81a74abc0136d8f898f46e8b029db 845 Pfam PF00246 Zinc carboxypeptidase 110 285 6.8E-23 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_14455 1331d22aa5a5e1a390c97e8ad1c8ce10 253 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 122 249 1.7E-31 T 12-10-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 AFR_14455 1331d22aa5a5e1a390c97e8ad1c8ce10 253 Gene3D G3DSA:2.80.10.50 109 253 4.2E-39 T 12-10-2018 AFR_14455 1331d22aa5a5e1a390c97e8ad1c8ce10 253 SUPERFAMILY SSF110221 118 240 3.01E-32 T 12-10-2018 IPR036195 Alpha-L-arabinofuranosidase B, arabinose-binding domain superfamily GO:0046373|GO:0046556 AFR_12710 790ed9980358fd6582bba69874654c43 360 SMART SM01329 5 353 1.5E-175 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFR_12710 790ed9980358fd6582bba69874654c43 360 SUPERFAMILY SSF53659 2 355 3.6E-114 T 12-10-2018 AFR_12710 790ed9980358fd6582bba69874654c43 360 Gene3D G3DSA:3.40.718.10 1 359 7.6E-136 T 12-10-2018 AFR_12710 790ed9980358fd6582bba69874654c43 360 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 356 1.1E-168 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 AFR_12710 790ed9980358fd6582bba69874654c43 360 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 243 262 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFR_12710 790ed9980358fd6582bba69874654c43 360 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 353 4.2E-86 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFR_27065 e0254e1d79c6e75650bc36a5caa2819a 259 SUPERFAMILY SSF53067 1 246 4.34E-36 T 12-10-2018 AFR_27065 e0254e1d79c6e75650bc36a5caa2819a 259 Gene3D G3DSA:3.30.420.40 1 104 1.9E-24 T 12-10-2018 AFR_27065 e0254e1d79c6e75650bc36a5caa2819a 259 Pfam PF00480 ROK family 4 159 2.1E-17 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_27065 e0254e1d79c6e75650bc36a5caa2819a 259 Gene3D G3DSA:3.30.420.40 105 247 1.4E-37 T 12-10-2018 AFR_38740 bd06f182e2af14ba56311ae3c89ba43b 361 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 5 360 2.3E-177 T 12-10-2018 IPR019880 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ AFR_38740 bd06f182e2af14ba56311ae3c89ba43b 361 Pfam PF00155 Aminotransferase class I and II 28 359 2.5E-45 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_38740 bd06f182e2af14ba56311ae3c89ba43b 361 Gene3D G3DSA:3.40.640.10 39 266 3.7E-85 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_38740 bd06f182e2af14ba56311ae3c89ba43b 361 Gene3D G3DSA:3.90.1150.10 17 352 3.7E-85 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_38740 bd06f182e2af14ba56311ae3c89ba43b 361 SUPERFAMILY SSF53383 18 359 2.96E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_38740 bd06f182e2af14ba56311ae3c89ba43b 361 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 217 230 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 Gene3D G3DSA:3.40.50.2300 108 302 1.7E-26 T 12-10-2018 AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 Gene3D G3DSA:1.10.260.40 1 53 4.7E-9 T 12-10-2018 AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 SUPERFAMILY SSF47413 5 47 7.55E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 SUPERFAMILY SSF53822 106 317 7.59E-23 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 SMART SM00354 4 71 4.7E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 Gene3D G3DSA:3.40.50.2300 165 300 1.7E-26 T 12-10-2018 AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 Pfam PF13407 Periplasmic binding protein domain 110 297 8.9E-23 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_03345 275afb73dffdaa2de10f8044274f1a4a 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 46 7.2E-7 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 PRINTS PR00412 Epoxide hydrolase signature 339 361 1.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 PRINTS PR00412 Epoxide hydrolase signature 177 190 1.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 PRINTS PR00412 Epoxide hydrolase signature 100 118 1.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 PRINTS PR00412 Epoxide hydrolase signature 308 324 1.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 Gene3D G3DSA:3.40.50.1820 10 368 2.0E-103 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 Pfam PF06441 Epoxide hydrolase N terminus 11 109 6.6E-20 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 PIRSF PIRSF001112 10 367 6.4E-70 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_11895 bcd0bea7e90bc9899cdb51af8b0608cc 370 SUPERFAMILY SSF53474 10 360 2.52E-74 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 Gene3D G3DSA:3.90.230.10 1 256 2.3E-68 T 12-10-2018 AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 SUPERFAMILY SSF55920 4 254 2.49E-62 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 3.7E-63 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 30.43 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 Pfam PF00557 Metallopeptidase family M24 14 246 5.5E-38 T 12-10-2018 IPR000994 Peptidase M24 AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 4.7E-15 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 4.7E-15 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 4.7E-15 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_11885 84300c54990f1c7b93f53c8a2217f83d 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 4.7E-15 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFR_31225 b67e2e9570154fe459d3f046dfe1a19f 157 Pfam PF12277 Protein of unknown function (DUF3618) 14 57 4.7E-14 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 AFR_31225 b67e2e9570154fe459d3f046dfe1a19f 157 Gene3D G3DSA:1.20.120.20 12 131 1.5E-5 T 12-10-2018 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 Gene3D G3DSA:3.90.740.10 197 392 1.9E-235 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 Gene3D G3DSA:1.10.730.10 633 817 2.6E-48 T 12-10-2018 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 6 826 4.1E-271 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 SUPERFAMILY SSF47323 647 885 1.36E-45 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 SUPERFAMILY SSF52374 5 641 3.22E-126 T 12-10-2018 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 Pfam PF08264 Anticodon-binding domain of tRNA 679 824 1.3E-27 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 620 4.7E-169 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 SUPERFAMILY SSF50677 203 388 5.13E-47 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 Gene3D G3DSA:3.40.50.620 16 618 1.9E-235 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1034 13.601 T 12-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 551 560 1.7E-27 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 41 52 1.7E-27 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 386 401 1.7E-27 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 511 524 1.7E-27 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_03465 207ad6d4df5cee7bdde1975b0da6a21f 1040 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 224 247 1.7E-27 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_25495 379de2fdb249ef2d4508f92d12c10ab2 224 Gene3D G3DSA:3.40.50.2300 1 120 1.9E-39 T 12-10-2018 AFR_25495 379de2fdb249ef2d4508f92d12c10ab2 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 5.1E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_25495 379de2fdb249ef2d4508f92d12c10ab2 224 Pfam PF00072 Response regulator receiver domain 3 112 1.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25495 379de2fdb249ef2d4508f92d12c10ab2 224 SMART SM00862 145 220 3.0E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_25495 379de2fdb249ef2d4508f92d12c10ab2 224 Gene3D G3DSA:1.10.10.10 124 224 3.3E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25495 379de2fdb249ef2d4508f92d12c10ab2 224 SMART SM00448 1 112 2.0E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25495 379de2fdb249ef2d4508f92d12c10ab2 224 SUPERFAMILY SSF52172 1 177 9.08E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFR_15850 d2d106823f354d7cf54034d0e719e631 194 SUPERFAMILY SSF48498 90 193 1.74E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_15850 d2d106823f354d7cf54034d0e719e631 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 2.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15850 d2d106823f354d7cf54034d0e719e631 194 SUPERFAMILY SSF46689 11 91 2.1E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15850 d2d106823f354d7cf54034d0e719e631 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15850 d2d106823f354d7cf54034d0e719e631 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15850 d2d106823f354d7cf54034d0e719e631 194 Gene3D G3DSA:1.10.357.10 6 194 1.4E-45 T 12-10-2018 AFR_15795 96a6d1be9abd5c9f6f857d1c8d856c5a 510 Gene3D G3DSA:2.160.20.10 35 357 8.7E-98 T 12-10-2018 IPR012334 Pectin lyase fold AFR_15795 96a6d1be9abd5c9f6f857d1c8d856c5a 510 Gene3D G3DSA:2.60.120.260 399 509 1.6E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15795 96a6d1be9abd5c9f6f857d1c8d856c5a 510 SUPERFAMILY SSF51126 35 357 2.51E-72 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_15795 96a6d1be9abd5c9f6f857d1c8d856c5a 510 Pfam PF00544 Pectate lyase 77 281 2.5E-33 T 12-10-2018 IPR002022 Pectate lyase AFR_15795 96a6d1be9abd5c9f6f857d1c8d856c5a 510 SUPERFAMILY SSF49785 380 508 1.59E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15795 96a6d1be9abd5c9f6f857d1c8d856c5a 510 SMART SM00656 77 287 5.0E-20 T 12-10-2018 IPR002022 Pectate lyase AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 Gene3D G3DSA:3.40.30.60 342 482 3.4E-41 T 12-10-2018 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 PIRSF PIRSF005419 2 677 2.4E-250 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 124 140 4.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 25 38 4.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 173 190 4.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 62 81 4.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 161 4.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 224 238 4.1E-57 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 Gene3D G3DSA:1.10.490.80 573 672 6.1E-13 T 12-10-2018 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 Gene3D G3DSA:1.10.8.540 483 572 8.3E-21 T 12-10-2018 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 129 152 - T 12-10-2018 IPR025505 FHIPEP conserved site AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 8 672 2.3E-234 T 12-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 AFR_40530 ab2b8c5281cd6248ba3926ee1e9a1aa1 680 Pfam PF00771 FHIPEP family 18 661 4.3E-245 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFR_33325 92cc4abc83388be59ec51bb4aab31185 346 SUPERFAMILY SSF50129 1 170 1.32E-51 T 12-10-2018 IPR011032 GroES-like superfamily AFR_33325 92cc4abc83388be59ec51bb4aab31185 346 Pfam PF00107 Zinc-binding dehydrogenase 176 302 3.1E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_33325 92cc4abc83388be59ec51bb4aab31185 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_33325 92cc4abc83388be59ec51bb4aab31185 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 127 5.9E-31 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_33325 92cc4abc83388be59ec51bb4aab31185 346 Gene3D G3DSA:3.90.180.10 1 342 2.1E-93 T 12-10-2018 AFR_33325 92cc4abc83388be59ec51bb4aab31185 346 SMART SM00829 10 339 1.2E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_33325 92cc4abc83388be59ec51bb4aab31185 346 SUPERFAMILY SSF51735 138 308 4.36E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_09360 fd84703762669be4595694bb87b9444a 378 Gene3D G3DSA:3.90.1510.10 50 279 5.6E-110 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 AFR_09360 fd84703762669be4595694bb87b9444a 378 Pfam PF02595 Glycerate kinase family 11 376 1.6E-116 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 AFR_09360 fd84703762669be4595694bb87b9444a 378 Gene3D G3DSA:3.40.50.10350 10 363 5.6E-110 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold AFR_09360 fd84703762669be4595694bb87b9444a 378 SUPERFAMILY SSF110738 10 376 4.05E-101 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 AFR_09360 fd84703762669be4595694bb87b9444a 378 PIRSF PIRSF006078 9 378 2.8E-113 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 AFR_09360 fd84703762669be4595694bb87b9444a 378 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 10 376 2.2E-100 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 AFR_21130 74a37ddc997cf8b33308d855aa29c4d1 99 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 6.4E-8 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_21130 74a37ddc997cf8b33308d855aa29c4d1 99 SUPERFAMILY SSF50249 4 71 6.28E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_21130 74a37ddc997cf8b33308d855aa29c4d1 99 Gene3D G3DSA:2.40.50.140 3 69 3.8E-10 T 12-10-2018 AFR_30580 79877de66de305bd614d6ef6b7a2b7e5 409 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 370 1.1E-68 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFR_30580 79877de66de305bd614d6ef6b7a2b7e5 409 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 5 395 1.3E-118 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 AFR_30580 79877de66de305bd614d6ef6b7a2b7e5 409 SUPERFAMILY SSF52507 5 176 4.06E-57 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFR_30580 79877de66de305bd614d6ef6b7a2b7e5 409 Gene3D G3DSA:3.40.50.1950 3 181 2.5E-53 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFR_30580 79877de66de305bd614d6ef6b7a2b7e5 409 SUPERFAMILY SSF102645 185 400 1.57E-69 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFR_30580 79877de66de305bd614d6ef6b7a2b7e5 409 Gene3D G3DSA:3.40.50.10300 182 403 3.0E-77 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFR_30580 79877de66de305bd614d6ef6b7a2b7e5 409 Pfam PF02441 Flavoprotein 5 174 2.0E-39 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFR_36060 8b5b03a00031ebee7170a22de0e6aa32 508 Gene3D G3DSA:1.20.1740.10 33 485 4.4E-34 T 12-10-2018 AFR_36060 8b5b03a00031ebee7170a22de0e6aa32 508 Pfam PF13520 Amino acid permease 27 470 4.8E-66 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_36060 8b5b03a00031ebee7170a22de0e6aa32 508 PIRSF PIRSF006060 4 502 1.3E-62 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_13765 a4073f89ff7c3687b6d8cd868e15a407 538 Pfam PF00535 Glycosyl transferase family 2 104 265 2.3E-26 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_13765 a4073f89ff7c3687b6d8cd868e15a407 538 Pfam PF03552 Cellulose synthase 266 369 4.7E-13 T 12-10-2018 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 AFR_13765 a4073f89ff7c3687b6d8cd868e15a407 538 PRINTS PR01439 Cellulose synthase subunit A signature 110 129 4.3E-7 T 12-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 AFR_13765 a4073f89ff7c3687b6d8cd868e15a407 538 PRINTS PR01439 Cellulose synthase subunit A signature 344 370 4.3E-7 T 12-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 AFR_13765 a4073f89ff7c3687b6d8cd868e15a407 538 PRINTS PR01439 Cellulose synthase subunit A signature 447 471 4.3E-7 T 12-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 AFR_13765 a4073f89ff7c3687b6d8cd868e15a407 538 Gene3D G3DSA:3.90.550.10 93 303 2.3E-68 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_13765 a4073f89ff7c3687b6d8cd868e15a407 538 SUPERFAMILY SSF53448 103 363 1.62E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 SMART SM00495 33 78 2.3E-11 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 ProSitePatterns PS01095 Chitinases family 18 active site. 239 247 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 SMART SM00636 127 445 7.6E-6 T 12-10-2018 IPR011583 Chitinase II GO:0008061 AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 Gene3D G3DSA:3.20.20.80 122 464 5.2E-85 T 12-10-2018 AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 Gene3D G3DSA:2.10.10.20 30 82 1.1E-17 T 12-10-2018 AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 SUPERFAMILY SSF51445 126 454 5.33E-52 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 SUPERFAMILY SSF51055 30 81 9.61E-14 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_37910 5efb29734b1945f2199588c39bafcfb1 464 Pfam PF00704 Glycosyl hydrolases family 18 129 445 2.0E-26 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_21985 64ee435a93b062003b83515973dc2d2e 294 SUPERFAMILY SSF50370 169 293 1.27E-25 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_21985 64ee435a93b062003b83515973dc2d2e 294 SMART SM00458 173 294 3.1E-17 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_21985 64ee435a93b062003b83515973dc2d2e 294 Gene3D G3DSA:2.80.10.50 169 293 1.8E-27 T 12-10-2018 AFR_21985 64ee435a93b062003b83515973dc2d2e 294 Pfam PF00652 Ricin-type beta-trefoil lectin domain 176 291 1.8E-16 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 Pfam PF01433 Peptidase family M1 domain 259 396 6.8E-26 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 SUPERFAMILY SSF55486 180 404 9.52E-53 T 12-10-2018 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 SUPERFAMILY SSF63737 1 172 9.81E-29 T 12-10-2018 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 Gene3D G3DSA:2.60.40.1730 1 174 5.5E-23 T 12-10-2018 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 Gene3D G3DSA:1.10.390.60 175 400 3.8E-38 T 12-10-2018 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 156 171 6.8E-12 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 276 6.8E-12 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 109 124 6.8E-12 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_04960 c910b99f57dd798b2bf44d9bad0ed8dd 405 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 280 292 6.8E-12 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_05505 24db51b85635707e50af97aaf4fe759d 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 385 4.4E-143 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFR_05505 24db51b85635707e50af97aaf4fe759d 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 198 212 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFR_05505 24db51b85635707e50af97aaf4fe759d 386 Gene3D G3DSA:3.90.1150.10 257 386 2.0E-49 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_05505 24db51b85635707e50af97aaf4fe759d 386 Gene3D G3DSA:3.40.640.10 4 256 2.3E-99 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_05505 24db51b85635707e50af97aaf4fe759d 386 SUPERFAMILY SSF53383 12 385 2.55E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_05505 24db51b85635707e50af97aaf4fe759d 386 PIRSF PIRSF001434 2 386 3.5E-141 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFR_20140 55b950be8e556f0e68d668abe10a3cbf 326 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 198 1.9E-46 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFR_20140 55b950be8e556f0e68d668abe10a3cbf 326 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 315 6.2E-78 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFR_03985 c314b8c767ed91d3b56df893bbd2b799 396 Gene3D G3DSA:3.40.50.2300 9 155 1.7E-19 T 12-10-2018 AFR_03985 c314b8c767ed91d3b56df893bbd2b799 396 SUPERFAMILY SSF52172 15 177 2.85E-22 T 12-10-2018 IPR011006 CheY-like superfamily AFR_03985 c314b8c767ed91d3b56df893bbd2b799 396 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 200 392 1.3E-31 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_03985 c314b8c767ed91d3b56df893bbd2b799 396 SMART SM00331 170 392 6.1E-14 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_03985 c314b8c767ed91d3b56df893bbd2b799 396 Gene3D G3DSA:3.60.40.10 167 393 2.2E-37 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_03985 c314b8c767ed91d3b56df893bbd2b799 396 Pfam PF00072 Response regulator receiver domain 19 119 2.6E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_03985 c314b8c767ed91d3b56df893bbd2b799 396 SMART SM00448 17 128 1.2E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 182 4.6E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 SUPERFAMILY SSF110221 404 506 1.57E-30 T 12-10-2018 IPR036195 Alpha-L-arabinofuranosidase B, arabinose-binding domain superfamily GO:0046373|GO:0046556 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 374 502 7.2E-37 T 12-10-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 Gene3D G3DSA:1.10.1740.10 2 108 3.9E-20 T 12-10-2018 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 Gene3D G3DSA:2.80.10.50 362 507 6.5E-38 T 12-10-2018 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 Pfam PF04542 Sigma-70 region 2 26 91 2.1E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 77 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 Gene3D G3DSA:1.10.10.10 109 189 8.2E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14930 a66c13bc6ed91cf15b8456e7ea93776c 507 SUPERFAMILY SSF88946 7 95 8.95E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_28320 9f26fa2c887d71a7d2abf78e52b48437 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 66 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28320 9f26fa2c887d71a7d2abf78e52b48437 210 Gene3D G3DSA:1.10.357.10 17 201 7.3E-22 T 12-10-2018 AFR_28320 9f26fa2c887d71a7d2abf78e52b48437 210 SUPERFAMILY SSF46689 11 76 5.03E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 38 97 1.2E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 Pfam PF03466 LysR substrate binding domain 124 314 6.3E-22 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 Gene3D G3DSA:1.10.10.10 32 119 2.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 SUPERFAMILY SSF53850 126 316 7.24E-24 T 12-10-2018 AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 SUPERFAMILY SSF46785 36 120 5.88E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 Gene3D G3DSA:3.40.190.10 135 301 1.8E-20 T 12-10-2018 AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 Gene3D G3DSA:3.40.190.10 192 286 1.8E-20 T 12-10-2018 AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 74 85 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_35095 1a0890c8258df6bfcb6b09123d01edb7 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 74 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 238 329 1.3E-9 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 Gene3D G3DSA:3.20.20.10 4 237 1.0E-84 T 12-10-2018 IPR029066 PLP-binding barrel AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 329 342 6.7E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 44 56 6.7E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 146 159 6.7E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 24 42 6.7E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 227 246 6.7E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 Gene3D G3DSA:2.40.37.10 3 342 1.0E-84 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 24 42 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01182 Ornithine decarboxylase signature 66 90 2.6E-19 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01182 Ornithine decarboxylase signature 96 118 2.6E-19 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01182 Ornithine decarboxylase signature 295 305 2.6E-19 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01182 Ornithine decarboxylase signature 316 329 2.6E-19 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 PRINTS PR01182 Ornithine decarboxylase signature 22 49 2.6E-19 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 4 237 2.0E-45 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 SUPERFAMILY SSF50621 217 349 3.98E-29 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_24150 0eab0de842f22e777ae3d5e89b04366a 350 SUPERFAMILY SSF51419 4 239 1.14E-52 T 12-10-2018 IPR029066 PLP-binding barrel AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 6.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 Gene3D G3DSA:3.40.50.720 1 286 1.5E-85 T 12-10-2018 AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 6.2E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.2E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 6.2E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.2E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.2E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 SUPERFAMILY SSF51735 12 236 2.52E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14830 ac7e88e8625ad156d4af751ab93fd3cf 290 Pfam PF00106 short chain dehydrogenase 16 206 7.2E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38655 ef4940d944def8eb7506fb5d56b243eb 376 Pfam PF00534 Glycosyl transferases group 1 198 343 2.8E-25 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_38655 ef4940d944def8eb7506fb5d56b243eb 376 SUPERFAMILY SSF53756 15 363 7.33E-68 T 12-10-2018 AFR_38655 ef4940d944def8eb7506fb5d56b243eb 376 Gene3D G3DSA:3.40.50.2000 3 183 5.5E-14 T 12-10-2018 AFR_38655 ef4940d944def8eb7506fb5d56b243eb 376 Gene3D G3DSA:3.40.50.2000 184 349 1.3E-38 T 12-10-2018 AFR_38655 ef4940d944def8eb7506fb5d56b243eb 376 Pfam PF13439 Glycosyltransferase Family 4 17 177 5.5E-13 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_22805 61dc1ce049c68184109f4f38ba3e3a89 402 PIRSF PIRSF006060 1 400 6.8E-59 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_22805 61dc1ce049c68184109f4f38ba3e3a89 402 Pfam PF13520 Amino acid permease 12 382 1.6E-36 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_22805 61dc1ce049c68184109f4f38ba3e3a89 402 Gene3D G3DSA:1.20.1740.10 3 402 8.0E-76 T 12-10-2018 AFR_09760 ca4dcae452ebc2805d2ac6299a6e72fb 385 Gene3D G3DSA:1.20.1250.20 1 380 8.9E-27 T 12-10-2018 AFR_09760 ca4dcae452ebc2805d2ac6299a6e72fb 385 Pfam PF07690 Major Facilitator Superfamily 11 226 2.6E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_09760 ca4dcae452ebc2805d2ac6299a6e72fb 385 SUPERFAMILY SSF103473 2 379 1.31E-29 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_29280 7acc7257a9a895276bc29904988c3002 554 Pfam PF00390 Malic enzyme, N-terminal domain 73 255 9.7E-64 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFR_29280 7acc7257a9a895276bc29904988c3002 554 SUPERFAMILY SSF53223 10 264 1.01E-88 T 12-10-2018 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PRINTS PR00072 Malic enzyme signature 236 254 2.8E-65 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PRINTS PR00072 Malic enzyme signature 402 418 2.8E-65 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PRINTS PR00072 Malic enzyme signature 292 308 2.8E-65 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PRINTS PR00072 Malic enzyme signature 79 103 2.8E-65 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PRINTS PR00072 Malic enzyme signature 141 170 2.8E-65 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PRINTS PR00072 Malic enzyme signature 177 199 2.8E-65 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PRINTS PR00072 Malic enzyme signature 261 277 2.8E-65 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 SMART SM01274 73 255 6.5E-82 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFR_29280 7acc7257a9a895276bc29904988c3002 554 SMART SM00919 265 524 5.8E-100 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFR_29280 7acc7257a9a895276bc29904988c3002 554 Pfam PF03949 Malic enzyme, NAD binding domain 265 523 6.9E-92 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFR_29280 7acc7257a9a895276bc29904988c3002 554 Gene3D G3DSA:3.40.50.10380 7 262 1.0E-89 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AFR_29280 7acc7257a9a895276bc29904988c3002 554 PIRSF PIRSF000106 2 554 2.2E-191 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFR_29280 7acc7257a9a895276bc29904988c3002 554 SUPERFAMILY SSF51735 266 549 1.63E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29280 7acc7257a9a895276bc29904988c3002 554 ProSitePatterns PS00331 Malic enzymes signature. 261 277 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 AFR_29280 7acc7257a9a895276bc29904988c3002 554 Gene3D G3DSA:3.40.50.720 263 554 3.8E-97 T 12-10-2018 AFR_22755 748a371ed347fd5df33c8154a0ac4375 312 SUPERFAMILY SSF161111 29 228 1.7E-46 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_22755 748a371ed347fd5df33c8154a0ac4375 312 Gene3D G3DSA:1.20.1510.10 31 227 2.1E-43 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_22755 748a371ed347fd5df33c8154a0ac4375 312 Pfam PF16916 Dimerisation domain of Zinc Transporter 231 308 4.5E-14 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFR_22755 748a371ed347fd5df33c8154a0ac4375 312 Pfam PF01545 Cation efflux family 34 227 1.2E-37 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_22755 748a371ed347fd5df33c8154a0ac4375 312 SUPERFAMILY SSF160240 229 309 5.36E-16 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFR_22755 748a371ed347fd5df33c8154a0ac4375 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 32 309 1.5E-66 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_22755 748a371ed347fd5df33c8154a0ac4375 312 Gene3D G3DSA:3.30.70.1350 229 306 5.3E-13 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFR_42170 92fa4433219e030680116c9871ec367c 773 PRINTS PR00364 Disease resistance protein signature 171 185 7.8E-6 T 12-10-2018 AFR_42170 92fa4433219e030680116c9871ec367c 773 PRINTS PR00364 Disease resistance protein signature 104 119 7.8E-6 T 12-10-2018 AFR_42170 92fa4433219e030680116c9871ec367c 773 PRINTS PR00364 Disease resistance protein signature 277 291 7.8E-6 T 12-10-2018 AFR_42170 92fa4433219e030680116c9871ec367c 773 SUPERFAMILY SSF52540 71 342 3.35E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42170 92fa4433219e030680116c9871ec367c 773 Gene3D G3DSA:1.25.40.10 469 764 4.2E-41 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_42170 92fa4433219e030680116c9871ec367c 773 SUPERFAMILY SSF48452 576 744 1.73E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_42170 92fa4433219e030680116c9871ec367c 773 SUPERFAMILY SSF48452 459 569 1.21E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_42170 92fa4433219e030680116c9871ec367c 773 SUPERFAMILY SSF47413 2 47 6.82E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_42170 92fa4433219e030680116c9871ec367c 773 SMART SM00028 574 607 0.45 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_42170 92fa4433219e030680116c9871ec367c 773 SMART SM00028 654 687 210.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_42170 92fa4433219e030680116c9871ec367c 773 SMART SM00028 534 567 12.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_42170 92fa4433219e030680116c9871ec367c 773 SMART SM00028 694 727 23.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_42170 92fa4433219e030680116c9871ec367c 773 Pfam PF13424 Tetratricopeptide repeat 615 685 3.9E-7 T 12-10-2018 AFR_42170 92fa4433219e030680116c9871ec367c 773 Pfam PF13424 Tetratricopeptide repeat 540 606 6.5E-10 T 12-10-2018 AFR_42170 92fa4433219e030680116c9871ec367c 773 Gene3D G3DSA:1.10.260.40 1 61 4.0E-8 T 12-10-2018 AFR_42170 92fa4433219e030680116c9871ec367c 773 Gene3D G3DSA:3.40.50.300 70 219 1.6E-17 T 12-10-2018 AFR_42170 92fa4433219e030680116c9871ec367c 773 Pfam PF13560 Helix-turn-helix domain 3 54 2.1E-7 T 12-10-2018 AFR_10545 8239980acf3c0f45e278981628cca35e 847 SUPERFAMILY SSF82771 17 101 1.06E-20 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFR_10545 8239980acf3c0f45e278981628cca35e 847 SMART SM00278 702 721 15.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_10545 8239980acf3c0f45e278981628cca35e 847 SMART SM00278 734 753 0.0028 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_10545 8239980acf3c0f45e278981628cca35e 847 Pfam PF01541 GIY-YIG catalytic domain 19 92 2.7E-9 T 12-10-2018 IPR000305 GIY-YIG endonuclease AFR_10545 8239980acf3c0f45e278981628cca35e 847 SMART SM00465 17 99 3.5E-18 T 12-10-2018 IPR000305 GIY-YIG endonuclease AFR_10545 8239980acf3c0f45e278981628cca35e 847 Gene3D G3DSA:1.10.150.20 696 755 1.4E-23 T 12-10-2018 AFR_10545 8239980acf3c0f45e278981628cca35e 847 SUPERFAMILY SSF46600 194 247 2.62E-14 T 12-10-2018 IPR036876 UVR domain superfamily AFR_10545 8239980acf3c0f45e278981628cca35e 847 SUPERFAMILY SSF47781 645 755 1.4E-27 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_10545 8239980acf3c0f45e278981628cca35e 847 Gene3D G3DSA:3.40.1440.10 7 103 6.8E-29 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFR_10545 8239980acf3c0f45e278981628cca35e 847 Gene3D G3DSA:4.10.860.10 206 245 1.1E-7 T 12-10-2018 AFR_10545 8239980acf3c0f45e278981628cca35e 847 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 394 688 2.9E-49 T 12-10-2018 IPR001162 UvrC family homology region AFR_10545 8239980acf3c0f45e278981628cca35e 847 Pfam PF14520 Helix-hairpin-helix domain 704 754 2.1E-9 T 12-10-2018 AFR_10545 8239980acf3c0f45e278981628cca35e 847 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 468 3.1E-127 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 AFR_10545 8239980acf3c0f45e278981628cca35e 847 Gene3D G3DSA:3.30.420.340 604 695 1.2E-23 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily AFR_10545 8239980acf3c0f45e278981628cca35e 847 Gene3D G3DSA:3.30.420.340 386 477 6.8E-24 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily AFR_10545 8239980acf3c0f45e278981628cca35e 847 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 753 30.095 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 AFR_10545 8239980acf3c0f45e278981628cca35e 847 Pfam PF02151 UvrB/uvrC motif 210 242 4.3E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 AFR_08690 7e5f7da35d9a8cd7dff3f249614252d6 80 Gene3D G3DSA:1.10.1200.10 1 80 4.4E-25 T 12-10-2018 IPR036736 ACP-like superfamily AFR_08690 7e5f7da35d9a8cd7dff3f249614252d6 80 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 6 79 3.2E-21 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFR_08690 7e5f7da35d9a8cd7dff3f249614252d6 80 Pfam PF00550 Phosphopantetheine attachment site 11 76 1.3E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_08690 7e5f7da35d9a8cd7dff3f249614252d6 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 77 1.0E-13 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFR_08690 7e5f7da35d9a8cd7dff3f249614252d6 80 SUPERFAMILY SSF47336 2 79 4.06E-21 T 12-10-2018 IPR036736 ACP-like superfamily AFR_08690 7e5f7da35d9a8cd7dff3f249614252d6 80 Hamap MF_01217 Acyl carrier protein [acpP]. 6 80 17.539 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFR_32775 e9a6583d588b41b56aebaeb17a4dd58a 171 Gene3D G3DSA:2.30.110.10 9 171 9.5E-48 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_32775 e9a6583d588b41b56aebaeb17a4dd58a 171 SMART SM00903 21 166 5.4E-48 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AFR_32775 e9a6583d588b41b56aebaeb17a4dd58a 171 SUPERFAMILY SSF50475 12 166 1.62E-40 T 12-10-2018 AFR_32775 e9a6583d588b41b56aebaeb17a4dd58a 171 Pfam PF01613 Flavin reductase like domain 22 167 8.7E-38 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AFR_12590 7bcec28e363b2f3ecf44cde15496953b 478 Pfam PF01547 Bacterial extracellular solute-binding protein 75 370 1.1E-21 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_12590 7bcec28e363b2f3ecf44cde15496953b 478 SUPERFAMILY SSF53850 69 467 2.36E-41 T 12-10-2018 AFR_12590 7bcec28e363b2f3ecf44cde15496953b 478 Gene3D G3DSA:3.40.190.10 64 470 5.3E-43 T 12-10-2018 AFR_33195 09eec6de247df7ee2904068cc31708a4 598 Pfam PF07676 WD40-like Beta Propeller Repeat 36 58 3.8E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_33195 09eec6de247df7ee2904068cc31708a4 598 SUPERFAMILY SSF53474 338 585 1.92E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33195 09eec6de247df7ee2904068cc31708a4 598 Gene3D G3DSA:3.40.50.1820 320 589 8.8E-75 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33195 09eec6de247df7ee2904068cc31708a4 598 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 362 380 1.6E-7 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_33195 09eec6de247df7ee2904068cc31708a4 598 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 446 466 1.6E-7 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_33195 09eec6de247df7ee2904068cc31708a4 598 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 388 412 1.6E-7 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AFR_33195 09eec6de247df7ee2904068cc31708a4 598 SUPERFAMILY SSF82171 32 317 1.14E-25 T 12-10-2018 AFR_33195 09eec6de247df7ee2904068cc31708a4 598 Pfam PF00326 Prolyl oligopeptidase family 383 585 4.2E-47 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AFR_33195 09eec6de247df7ee2904068cc31708a4 598 Gene3D G3DSA:2.120.10.30 19 225 5.6E-20 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_07150 32f5520573006d3298715f620494a1c2 215 Gene3D G3DSA:1.25.40.10 101 215 8.8E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_07150 32f5520573006d3298715f620494a1c2 215 SUPERFAMILY SSF48452 100 209 9.86E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_07150 32f5520573006d3298715f620494a1c2 215 SUPERFAMILY SSF46894 2 95 3.68E-9 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_07150 32f5520573006d3298715f620494a1c2 215 Gene3D G3DSA:1.10.10.10 1 97 4.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07150 32f5520573006d3298715f620494a1c2 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 95 1.1E-4 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_07150 32f5520573006d3298715f620494a1c2 215 SMART SM01043 102 214 5.8E-6 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_07150 32f5520573006d3298715f620494a1c2 215 SMART SM00862 16 95 2.2E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_07150 32f5520573006d3298715f620494a1c2 215 Pfam PF03704 Bacterial transcriptional activator domain 102 206 6.1E-7 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_20090 a413be0190df59cbf5e3e885c81920da 137 Pfam PF07498 Rho termination factor, N-terminal domain 95 122 1.5E-6 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFR_20090 a413be0190df59cbf5e3e885c81920da 137 Pfam PF06150 ChaB 7 61 1.9E-17 T 12-10-2018 IPR009317 ChaB AFR_20090 a413be0190df59cbf5e3e885c81920da 137 SUPERFAMILY SSF140376 4 62 6.93E-15 T 12-10-2018 IPR037205 ChaB superfamily AFR_20090 a413be0190df59cbf5e3e885c81920da 137 Gene3D G3DSA:1.10.1740.70 2 62 1.0E-6 T 12-10-2018 AFR_32925 7f85cf23c389520fbeadcfd94c373e37 298 SMART SM00829 6 294 1.3E-18 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_32925 7f85cf23c389520fbeadcfd94c373e37 298 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 23 89 1.4E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_32925 7f85cf23c389520fbeadcfd94c373e37 298 Pfam PF13602 Zinc-binding dehydrogenase 193 294 8.5E-10 T 12-10-2018 AFR_32925 7f85cf23c389520fbeadcfd94c373e37 298 Gene3D G3DSA:3.40.50.720 120 246 3.2E-68 T 12-10-2018 AFR_32925 7f85cf23c389520fbeadcfd94c373e37 298 Gene3D G3DSA:3.90.180.10 4 293 3.2E-68 T 12-10-2018 AFR_32925 7f85cf23c389520fbeadcfd94c373e37 298 SUPERFAMILY SSF51735 109 220 1.97E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_32925 7f85cf23c389520fbeadcfd94c373e37 298 SUPERFAMILY SSF50129 4 140 4.41E-30 T 12-10-2018 IPR011032 GroES-like superfamily AFR_38135 8f247ef29ccc3018b2b50a30bce64ca1 229 Gene3D G3DSA:3.90.1680.10 1 217 1.0E-68 T 12-10-2018 IPR036590 SOS response associated peptidase-like AFR_38135 8f247ef29ccc3018b2b50a30bce64ca1 229 Pfam PF02586 SOS response associated peptidase (SRAP) 1 207 5.4E-63 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) AFR_38135 8f247ef29ccc3018b2b50a30bce64ca1 229 SUPERFAMILY SSF143081 2 215 5.36E-68 T 12-10-2018 IPR036590 SOS response associated peptidase-like AFR_08625 298479a911c65955be225a9564447e4d 331 Pfam PF00891 O-methyltransferase 91 313 2.8E-39 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 AFR_08625 298479a911c65955be225a9564447e4d 331 SUPERFAMILY SSF53335 82 319 3.47E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_08625 298479a911c65955be225a9564447e4d 331 Gene3D G3DSA:1.10.10.10 1 73 6.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08625 298479a911c65955be225a9564447e4d 331 PIRSF PIRSF005739 1 320 2.7E-21 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 AFR_08625 298479a911c65955be225a9564447e4d 331 Pfam PF16864 Dimerisation domain 1 82 2.5E-14 T 12-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain AFR_08625 298479a911c65955be225a9564447e4d 331 SUPERFAMILY SSF46785 1 76 8.16E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_08625 298479a911c65955be225a9564447e4d 331 Gene3D G3DSA:3.40.50.150 81 317 2.2E-62 T 12-10-2018 AFR_21930 3b42ace40df2c5f92f25d057aa9f5755 426 Gene3D G3DSA:3.30.565.10 292 419 8.6E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21930 3b42ace40df2c5f92f25d057aa9f5755 426 Pfam PF07730 Histidine kinase 216 282 3.7E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_21930 3b42ace40df2c5f92f25d057aa9f5755 426 SUPERFAMILY SSF55874 305 418 1.08E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_02055 57d5215a7fb87a1a0ae77c6cada54860 323 Pfam PF02735 Ku70/Ku80 beta-barrel domain 15 184 2.0E-41 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AFR_02055 57d5215a7fb87a1a0ae77c6cada54860 323 TIGRFAM TIGR02772 Ku_bact: Ku protein 5 260 1.6E-90 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFR_02055 57d5215a7fb87a1a0ae77c6cada54860 323 Gene3D G3DSA:2.40.290.10 6 184 4.8E-20 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily AFR_02055 57d5215a7fb87a1a0ae77c6cada54860 323 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 5 257 33.216 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFR_02055 57d5215a7fb87a1a0ae77c6cada54860 323 SMART SM00559 56 184 9.1E-39 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AFR_02055 57d5215a7fb87a1a0ae77c6cada54860 323 SUPERFAMILY SSF100939 4 261 1.29E-59 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily AFR_02055 57d5215a7fb87a1a0ae77c6cada54860 323 PIRSF PIRSF006493 3 322 4.0E-93 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 Pfam PF01479 S4 domain 99 145 3.1E-18 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 4.4E-30 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 32.659 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 SMART SM01390 3 97 9.6E-47 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 SUPERFAMILY SSF55174 3 208 3.66E-64 T 12-10-2018 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 1.4E-65 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 Gene3D G3DSA:3.10.290.10 97 193 5.7E-77 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 Gene3D G3DSA:1.10.1050.10 6 208 5.7E-77 T 12-10-2018 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04650 a5c953dc95aaf04405876f7f8a6b5b72 208 SMART SM00363 98 160 2.3E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_36945 8e4c926c3825ffb50b33a9ff47998b8d 358 SUPERFAMILY SSF110296 5 354 8.37E-62 T 12-10-2018 AFR_36945 8e4c926c3825ffb50b33a9ff47998b8d 358 Gene3D G3DSA:2.130.10.10 1 358 5.6E-120 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_00610 de5be1c8eb3c9be5136c667fdfab7a64 471 Gene3D G3DSA:3.30.1610.20 1 233 1.3E-95 T 12-10-2018 IPR038546 Hen1, N-terminal domain superfamily AFR_00610 de5be1c8eb3c9be5136c667fdfab7a64 471 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 244 4.3E-107 T 12-10-2018 IPR024740 Hen1, N-terminal AFR_00610 de5be1c8eb3c9be5136c667fdfab7a64 471 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 2 468 1.4E-195 T 12-10-2018 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial AFR_00610 de5be1c8eb3c9be5136c667fdfab7a64 471 Gene3D G3DSA:3.40.50.150 258 471 6.9E-66 T 12-10-2018 AFR_00610 de5be1c8eb3c9be5136c667fdfab7a64 471 SUPERFAMILY SSF53335 276 436 1.09E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_00610 de5be1c8eb3c9be5136c667fdfab7a64 471 Pfam PF13489 Methyltransferase domain 280 437 4.8E-10 T 12-10-2018 AFR_05395 dfd2cd05d395bffc76e60afcb1b8fc24 438 Gene3D G3DSA:3.50.50.100 1 392 1.9E-102 T 12-10-2018 AFR_05395 dfd2cd05d395bffc76e60afcb1b8fc24 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 90 108 7.3E-5 T 12-10-2018 AFR_05395 dfd2cd05d395bffc76e60afcb1b8fc24 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 7.3E-5 T 12-10-2018 AFR_05395 dfd2cd05d395bffc76e60afcb1b8fc24 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 1.7E-36 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_05395 dfd2cd05d395bffc76e60afcb1b8fc24 438 SUPERFAMILY SSF51905 151 328 1.2E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_05395 dfd2cd05d395bffc76e60afcb1b8fc24 438 SUPERFAMILY SSF51905 2 208 6.75E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_06890 d2ae50ed170decfac8efc6a15559fb3d 347 Gene3D G3DSA:3.20.20.140 47 309 3.4E-39 T 12-10-2018 AFR_06890 d2ae50ed170decfac8efc6a15559fb3d 347 SUPERFAMILY SSF51556 44 310 1.29E-39 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_06890 d2ae50ed170decfac8efc6a15559fb3d 347 Pfam PF01979 Amidohydrolase family 158 345 4.9E-13 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_09890 d92ae0a5797e3c358371fecfba314422 174 SUPERFAMILY SSF55399 86 173 6.28E-24 T 12-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 AFR_09890 d92ae0a5797e3c358371fecfba314422 174 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 86 164 5.0E-14 T 12-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 AFR_09890 d92ae0a5797e3c358371fecfba314422 174 Gene3D G3DSA:3.30.350.10 70 174 6.2E-29 T 12-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 AFR_09890 d92ae0a5797e3c358371fecfba314422 174 Pfam PF00720 Subtilisin inhibitor-like 81 160 9.5E-24 T 12-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 AFR_19060 39ae2ef898d542e344f2ee1b167477ce 190 SUPERFAMILY SSF48498 110 185 4.11E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_19060 39ae2ef898d542e344f2ee1b167477ce 190 SUPERFAMILY SSF46689 11 82 2.44E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19060 39ae2ef898d542e344f2ee1b167477ce 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 6.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19060 39ae2ef898d542e344f2ee1b167477ce 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19060 39ae2ef898d542e344f2ee1b167477ce 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 67 1.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19060 39ae2ef898d542e344f2ee1b167477ce 190 Gene3D G3DSA:1.10.357.10 5 190 4.3E-34 T 12-10-2018 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 Pfam PF06441 Epoxide hydrolase N terminus 36 140 5.2E-35 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 Gene3D G3DSA:3.40.50.1820 34 419 9.3E-127 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 PIRSF PIRSF001112 3 419 4.2E-137 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 PRINTS PR00412 Epoxide hydrolase signature 161 176 1.1E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 PRINTS PR00412 Epoxide hydrolase signature 392 414 1.1E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 PRINTS PR00412 Epoxide hydrolase signature 206 219 1.1E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 PRINTS PR00412 Epoxide hydrolase signature 360 376 1.1E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 PRINTS PR00412 Epoxide hydrolase signature 132 150 1.1E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_23060 b4c3a9d02a9797c481452e2c698eff8a 419 SUPERFAMILY SSF53474 33 417 1.02E-90 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_08115 da25e8c3461d78b1769aa1695276a5c3 134 Pfam PF13478 XdhC Rossmann domain 2 120 6.3E-19 T 12-10-2018 IPR027051 XdhC Rossmann domain AFR_08115 da25e8c3461d78b1769aa1695276a5c3 134 Gene3D G3DSA:3.40.50.720 1 127 1.1E-21 T 12-10-2018 AFR_37430 5d573e761be9697cdbe2320f36b876f3 355 Pfam PF09511 RNA ligase 54 173 3.7E-10 T 12-10-2018 IPR019039 RNA ligase T4 Rnl1, N-terminal AFR_00190 1a7862b9d4ad9278947d2474cde72e1c 508 Pfam PF01039 Carboxyl transferase domain 28 505 3.2E-146 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFR_00190 1a7862b9d4ad9278947d2474cde72e1c 508 SUPERFAMILY SSF52096 212 488 2.74E-77 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_00190 1a7862b9d4ad9278947d2474cde72e1c 508 Gene3D G3DSA:3.90.226.10 3 246 7.3E-73 T 12-10-2018 AFR_00190 1a7862b9d4ad9278947d2474cde72e1c 508 SUPERFAMILY SSF52096 8 250 1.03E-62 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_00190 1a7862b9d4ad9278947d2474cde72e1c 508 Gene3D G3DSA:3.90.226.10 250 508 1.6E-78 T 12-10-2018 AFR_26120 d06b8a47c0994f8b78cabb0e90d3406b 293 Gene3D G3DSA:1.10.3720.10 23 280 1.6E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_26120 d06b8a47c0994f8b78cabb0e90d3406b 293 SUPERFAMILY SSF161098 23 293 1.57E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_26120 d06b8a47c0994f8b78cabb0e90d3406b 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 284 1.1E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 Gene3D G3DSA:3.30.420.40 163 347 1.4E-89 T 12-10-2018 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 SUPERFAMILY SSF53067 5 156 6.69E-20 T 12-10-2018 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 Pfam PF13360 PQQ-like domain 586 789 6.4E-8 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 Gene3D G3DSA:3.90.640.10 210 297 1.4E-89 T 12-10-2018 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 319 333 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 SUPERFAMILY SSF50998 564 854 1.75E-10 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 PRINTS PR00301 70kDa heat shock protein signature 347 367 1.6E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 PRINTS PR00301 70kDa heat shock protein signature 178 188 1.6E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 PRINTS PR00301 70kDa heat shock protein signature 5 18 1.6E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 PRINTS PR00301 70kDa heat shock protein signature 316 332 1.6E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.6E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 Gene3D G3DSA:3.30.420.40 7 357 1.4E-89 T 12-10-2018 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 Pfam PF00012 Hsp70 protein 86 405 3.5E-21 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 Gene3D G3DSA:2.40.128.630 559 692 7.3E-6 T 12-10-2018 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 SUPERFAMILY SSF53067 169 361 1.09E-29 T 12-10-2018 AFR_41090 2951bce0769e9af9b84240f9b0a8e61a 960 Gene3D G3DSA:2.130.10.10 698 912 9.1E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 412 41.848 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 Pfam PF00171 Aldehyde dehydrogenase family 8 278 1.9E-11 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 10 402 2.2E-149 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 Gene3D G3DSA:3.40.605.10 16 407 5.4E-160 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 Gene3D G3DSA:3.40.309.10 223 370 5.4E-160 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 PIRSF PIRSF000151 1 412 3.4E-171 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 SUPERFAMILY SSF53720 5 412 9.42E-114 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_04155 181f7f65ae0fb926f757626036dbd6e1 412 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 319 340 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 22 503 36.029 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 Gene3D G3DSA:2.40.50.140 17 155 1.3E-39 T 12-10-2018 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 Pfam PF00152 tRNA synthetases class II (D, K and N) 163 500 1.5E-67 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 SUPERFAMILY SSF55681 163 501 3.45E-98 T 12-10-2018 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 Pfam PF01336 OB-fold nucleic acid binding domain 70 145 3.2E-12 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 Gene3D G3DSA:3.30.930.10 161 503 1.5E-108 T 12-10-2018 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 17 502 4.6E-144 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 SUPERFAMILY SSF50249 15 155 4.29E-36 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 1.0E-32 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 1.0E-32 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 1.0E-32 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 1.0E-32 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_41365 583a6c2d72ba0f145c8ce4a20a85938e 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 1.0E-32 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_20445 a1289050f8b362c008b3e3d7f396b7d2 124 Pfam PF13564 DoxX-like family 7 114 7.4E-27 T 12-10-2018 IPR032808 DoxX family AFR_17950 24ac48bd98a5832a7b6e2c8987c91ec4 265 Gene3D G3DSA:1.10.260.40 26 92 2.1E-6 T 12-10-2018 AFR_17950 24ac48bd98a5832a7b6e2c8987c91ec4 265 Pfam PF13560 Helix-turn-helix domain 5 84 1.7E-13 T 12-10-2018 AFR_17950 24ac48bd98a5832a7b6e2c8987c91ec4 265 SUPERFAMILY SSF47413 29 79 9.96E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_17950 24ac48bd98a5832a7b6e2c8987c91ec4 265 SMART SM00530 9 81 5.6E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_17950 24ac48bd98a5832a7b6e2c8987c91ec4 265 Gene3D G3DSA:3.30.450.180 104 259 7.1E-7 T 12-10-2018 AFR_23010 3d83ad7dfd98889e053e49033802cd29 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 6.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23010 3d83ad7dfd98889e053e49033802cd29 204 SUPERFAMILY SSF46689 7 77 4.93E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_23010 3d83ad7dfd98889e053e49033802cd29 204 Gene3D G3DSA:1.10.357.10 7 196 5.0E-23 T 12-10-2018 AFR_23010 3d83ad7dfd98889e053e49033802cd29 204 SUPERFAMILY SSF48498 97 200 8.9E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_23010 3d83ad7dfd98889e053e49033802cd29 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23010 3d83ad7dfd98889e053e49033802cd29 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_41535 c532ca4e5b9e80f9bfbd8c73e9c980d7 148 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 23 39 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFR_41535 c532ca4e5b9e80f9bfbd8c73e9c980d7 148 Gene3D G3DSA:3.30.1130.10 13 148 2.1E-58 T 12-10-2018 AFR_41535 c532ca4e5b9e80f9bfbd8c73e9c980d7 148 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 2 146 9.4E-58 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFR_41535 c532ca4e5b9e80f9bfbd8c73e9c980d7 148 SUPERFAMILY SSF55620 1 146 1.93E-60 T 12-10-2018 AFR_41535 c532ca4e5b9e80f9bfbd8c73e9c980d7 148 Pfam PF01227 GTP cyclohydrolase I 1 145 8.3E-61 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFR_41535 c532ca4e5b9e80f9bfbd8c73e9c980d7 148 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 73 83 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFR_36655 e4ed5d9fa0bfed4ae2004cb859a55dc5 242 SMART SM00563 41 159 4.2E-34 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_36655 e4ed5d9fa0bfed4ae2004cb859a55dc5 242 SUPERFAMILY SSF69593 9 217 3.01E-39 T 12-10-2018 AFR_36655 e4ed5d9fa0bfed4ae2004cb859a55dc5 242 Pfam PF01553 Acyltransferase 28 155 1.0E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_02780 d8f47605b69476a443beaa49eb358f1f 694 SUPERFAMILY SSF82866 78 297 2.49E-25 T 12-10-2018 AFR_02780 d8f47605b69476a443beaa49eb358f1f 694 Pfam PF03176 MMPL family 50 328 6.9E-38 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_02780 d8f47605b69476a443beaa49eb358f1f 694 Pfam PF03176 MMPL family 420 664 1.9E-32 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_02780 d8f47605b69476a443beaa49eb358f1f 694 Gene3D G3DSA:1.20.1640.10 480 660 1.3E-6 T 12-10-2018 AFR_02780 d8f47605b69476a443beaa49eb358f1f 694 SUPERFAMILY SSF82866 443 656 2.22E-28 T 12-10-2018 AFR_10790 fba07b92b3f73e57bc3d6ffb81155447 130 Pfam PF00378 Enoyl-CoA hydratase/isomerase 1 118 4.6E-22 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_10790 fba07b92b3f73e57bc3d6ffb81155447 130 SUPERFAMILY SSF52096 1 123 1.45E-31 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_10790 fba07b92b3f73e57bc3d6ffb81155447 130 Gene3D G3DSA:3.90.226.10 1 128 1.2E-34 T 12-10-2018 AFR_28930 6c00585c69ae928c6184b97c88c066e0 122 SUPERFAMILY SSF54506 20 119 2.9E-11 T 12-10-2018 AFR_28930 6c00585c69ae928c6184b97c88c066e0 122 Gene3D G3DSA:3.10.310.10 22 117 3.0E-5 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 SUPERFAMILY SSF51905 146 315 9.3E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.6E-26 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.6E-26 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.6E-26 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.6E-26 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.6E-26 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 Pfam PF14759 Reductase C-terminal 325 414 1.0E-13 T 12-10-2018 IPR028202 Reductase, C-terminal AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 306 7.4E-62 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 SUPERFAMILY SSF55424 319 414 1.65E-22 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 Gene3D G3DSA:3.30.390.30 325 415 4.8E-19 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 Gene3D G3DSA:3.50.50.60 116 243 1.9E-107 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 Gene3D G3DSA:3.50.50.60 8 306 1.9E-107 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 SUPERFAMILY SSF51905 5 186 1.11E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 4.2E-17 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 4.2E-17 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.2E-17 T 12-10-2018 AFR_27755 090af3bb19e39fbf531c1217abf88aaa 415 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 4.2E-17 T 12-10-2018 AFR_28115 12814c826056e12b56646ed1b8eb03fe 319 Gene3D G3DSA:3.40.190.10 246 318 1.4E-9 T 12-10-2018 AFR_28115 12814c826056e12b56646ed1b8eb03fe 319 Gene3D G3DSA:3.10.105.10 23 120 1.7E-10 T 12-10-2018 AFR_28115 12814c826056e12b56646ed1b8eb03fe 319 Gene3D G3DSA:3.40.190.100 122 245 7.6E-22 T 12-10-2018 AFR_28115 12814c826056e12b56646ed1b8eb03fe 319 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 39 306 1.8E-41 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 AFR_28115 12814c826056e12b56646ed1b8eb03fe 319 SUPERFAMILY SSF53850 33 317 8.14E-51 T 12-10-2018 AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.0E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 SUPERFAMILY SSF51735 4 271 1.36E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 Gene3D G3DSA:3.40.50.720 1 275 2.0E-67 T 12-10-2018 AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 193 5.0E-5 T 12-10-2018 AFR_03055 a01b3e41b0c3214380f8909f2be26005 276 Pfam PF00106 short chain dehydrogenase 10 199 5.1E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38715 05e7c997561c570befbb552c2379f9ff 284 PIRSF PIRSF000097 1 281 1.5E-80 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38715 05e7c997561c570befbb552c2379f9ff 284 Pfam PF00248 Aldo/keto reductase family 25 263 1.0E-39 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_38715 05e7c997561c570befbb552c2379f9ff 284 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFR_38715 05e7c997561c570befbb552c2379f9ff 284 PRINTS PR00069 Aldo-keto reductase signature 38 62 4.2E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38715 05e7c997561c570befbb552c2379f9ff 284 PRINTS PR00069 Aldo-keto reductase signature 94 112 4.2E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38715 05e7c997561c570befbb552c2379f9ff 284 PRINTS PR00069 Aldo-keto reductase signature 128 145 4.2E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38715 05e7c997561c570befbb552c2379f9ff 284 PRINTS PR00069 Aldo-keto reductase signature 162 191 4.2E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38715 05e7c997561c570befbb552c2379f9ff 284 PRINTS PR00069 Aldo-keto reductase signature 199 223 4.2E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38715 05e7c997561c570befbb552c2379f9ff 284 SUPERFAMILY SSF51430 8 267 6.29E-86 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_38715 05e7c997561c570befbb552c2379f9ff 284 Gene3D G3DSA:3.20.20.100 1 277 8.1E-106 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_38715 05e7c997561c570befbb552c2379f9ff 284 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 42 59 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFR_17435 44adfde1c9bcc7fc378aab026a401320 156 Pfam PF01847 VHL beta domain 77 136 4.1E-8 T 12-10-2018 IPR024053 von Hippel-Lindau disease tumour suppressor, beta domain AFR_17435 44adfde1c9bcc7fc378aab026a401320 156 Gene3D G3DSA:2.60.40.780 70 154 1.7E-16 T 12-10-2018 IPR037140 von Hippel-Lindau disease tumour suppressor, beta domain superfamily AFR_17435 44adfde1c9bcc7fc378aab026a401320 156 SUPERFAMILY SSF49468 77 140 1.57E-15 T 12-10-2018 IPR036208 VHL superfamily AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 Gene3D G3DSA:2.60.40.10 644 755 1.3E-24 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 370 641 2.0E-40 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 Gene3D G3DSA:3.20.20.300 2 351 1.3E-117 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 SUPERFAMILY SSF52279 370 643 1.31E-39 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 Pfam PF14310 Fibronectin type III-like domain 678 747 1.5E-14 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 Gene3D G3DSA:3.40.50.1700 356 642 7.6E-60 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 SUPERFAMILY SSF51445 5 369 6.84E-110 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 SMART SM01217 678 747 7.5E-21 T 12-10-2018 IPR026891 Fibronectin type III-like domain AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 144 160 2.7E-25 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 181 197 2.7E-25 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 98 117 2.7E-25 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 74 90 2.7E-25 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 251 269 2.7E-25 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_30325 4aa1e418995a96c2f3d0cff57af0f0a4 760 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 26 331 1.0E-68 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 Gene3D G3DSA:1.10.1040.10 287 491 2.0E-65 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 SUPERFAMILY SSF48179 288 488 3.06E-58 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 PRINTS PR00084 Mannitol dehydrogenase signature 223 236 6.1E-21 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 PRINTS PR00084 Mannitol dehydrogenase signature 184 197 6.1E-21 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 PRINTS PR00084 Mannitol dehydrogenase signature 30 40 6.1E-21 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 PRINTS PR00084 Mannitol dehydrogenase signature 253 268 6.1E-21 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 SUPERFAMILY SSF51735 4 286 1.1E-105 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 223 235 - T 12-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 29 193 6.8E-45 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 221 465 4.7E-73 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 AFR_25800 bc10d43d8181c0ab29b37d2ed6a107e3 492 Gene3D G3DSA:3.40.50.720 3 286 1.7E-116 T 12-10-2018 AFR_11005 7efb84b293a7a8819b4d6715de8fd656 383 PIRSF PIRSF002849 5 339 9.9E-133 T 12-10-2018 AFR_11005 7efb84b293a7a8819b4d6715de8fd656 383 Gene3D G3DSA:1.10.8.300 217 334 1.2E-35 T 12-10-2018 AFR_11005 7efb84b293a7a8819b4d6715de8fd656 383 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 58 188 2.1E-62 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_11005 7efb84b293a7a8819b4d6715de8fd656 383 SUPERFAMILY SSF52540 28 309 2.18E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11005 7efb84b293a7a8819b4d6715de8fd656 383 Gene3D G3DSA:3.40.50.300 39 205 3.9E-44 T 12-10-2018 AFR_42400 032e5a0a8bec1bfb66a6daaa8c16a3e0 353 Gene3D G3DSA:3.40.50.1970 4 157 6.5E-26 T 12-10-2018 AFR_42400 032e5a0a8bec1bfb66a6daaa8c16a3e0 353 Gene3D G3DSA:1.20.1090.10 159 348 1.6E-42 T 12-10-2018 AFR_42400 032e5a0a8bec1bfb66a6daaa8c16a3e0 353 PIRSF PIRSF000112 1 351 4.1E-73 T 12-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFR_42400 032e5a0a8bec1bfb66a6daaa8c16a3e0 353 SUPERFAMILY SSF56796 8 345 3.14E-53 T 12-10-2018 AFR_42400 032e5a0a8bec1bfb66a6daaa8c16a3e0 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 267 3.3E-55 T 12-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFR_21805 9aca764b4b84ce0a3d6b8e6bb0f0af75 244 Pfam PF02310 B12 binding domain 104 230 3.9E-17 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_21805 9aca764b4b84ce0a3d6b8e6bb0f0af75 244 SUPERFAMILY SSF117778 15 66 2.75E-19 T 12-10-2018 IPR036843 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain superfamily GO:0046983 AFR_21805 9aca764b4b84ce0a3d6b8e6bb0f0af75 244 SUPERFAMILY SSF52242 91 240 3.66E-31 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_21805 9aca764b4b84ce0a3d6b8e6bb0f0af75 244 Gene3D G3DSA:3.40.50.280 84 241 5.2E-34 T 12-10-2018 AFR_21805 9aca764b4b84ce0a3d6b8e6bb0f0af75 244 Pfam PF16554 Dimerisation domain of d-ornithine 4,5-aminomutase 3 80 6.6E-33 T 12-10-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 AFR_21805 9aca764b4b84ce0a3d6b8e6bb0f0af75 244 Gene3D G3DSA:3.30.30.60 15 66 1.1E-22 T 12-10-2018 IPR036843 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain superfamily GO:0046983 AFR_03700 081df94c29decdba17e905e74bdf6111 964 SUPERFAMILY SSF69318 674 938 1.31E-17 T 12-10-2018 AFR_05290 58d5e9824889745960c821f99b692c10 1203 Gene3D G3DSA:3.40.50.11180 60 320 6.1E-60 T 12-10-2018 AFR_05290 58d5e9824889745960c821f99b692c10 1203 SMART SM00487 648 838 1.4E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_05290 58d5e9824889745960c821f99b692c10 1203 SMART SM01058 523 624 2.6E-51 T 12-10-2018 IPR003711 CarD-like/TRCF domain AFR_05290 58d5e9824889745960c821f99b692c10 1203 SUPERFAMILY SSF143517 1037 1192 4.18E-33 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain AFR_05290 58d5e9824889745960c821f99b692c10 1203 SUPERFAMILY SSF52540 574 831 2.77E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05290 58d5e9824889745960c821f99b692c10 1203 SUPERFAMILY SSF52540 830 1038 2.89E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05290 58d5e9824889745960c821f99b692c10 1203 Pfam PF00270 DEAD/DEAH box helicase 673 815 2.4E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_05290 58d5e9824889745960c821f99b692c10 1203 Gene3D G3DSA:3.40.50.300 590 829 3.4E-233 T 12-10-2018 AFR_05290 58d5e9824889745960c821f99b692c10 1203 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 168 1124 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFR_05290 58d5e9824889745960c821f99b692c10 1203 Gene3D G3DSA:2.30.30.840 527 589 3.4E-233 T 12-10-2018 AFR_05290 58d5e9824889745960c821f99b692c10 1203 SUPERFAMILY SSF141259 516 595 2.09E-19 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily AFR_05290 58d5e9824889745960c821f99b692c10 1203 SMART SM00490 874 958 6.2E-18 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_05290 58d5e9824889745960c821f99b692c10 1203 Gene3D G3DSA:3.40.50.300 523 1037 3.4E-233 T 12-10-2018 AFR_05290 58d5e9824889745960c821f99b692c10 1203 SMART SM00982 1051 1149 6.0E-35 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFR_05290 58d5e9824889745960c821f99b692c10 1203 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 46 1148 27.822 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFR_05290 58d5e9824889745960c821f99b692c10 1203 SUPERFAMILY SSF52540 35 357 5.31E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05290 58d5e9824889745960c821f99b692c10 1203 Pfam PF03461 TRCF domain 1052 1134 3.1E-23 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFR_05290 58d5e9824889745960c821f99b692c10 1203 SUPERFAMILY SSF52540 405 504 1.65E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05290 58d5e9824889745960c821f99b692c10 1203 Pfam PF00271 Helicase conserved C-terminal domain 858 957 2.1E-15 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_05290 58d5e9824889745960c821f99b692c10 1203 Gene3D G3DSA:3.90.1150.50 1047 1193 1.2E-24 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain AFR_05290 58d5e9824889745960c821f99b692c10 1203 Pfam PF02559 CarD-like/TRCF domain 524 623 1.3E-31 T 12-10-2018 IPR003711 CarD-like/TRCF domain AFR_05290 58d5e9824889745960c821f99b692c10 1203 Gene3D G3DSA:3.30.2060.10 151 237 6.1E-60 T 12-10-2018 AFR_02965 6850507f78d8fcf79ffd15d977888d00 106 SUPERFAMILY SSF52794 9 95 4.71E-17 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 AFR_02965 6850507f78d8fcf79ffd15d977888d00 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 11 91 4.4E-11 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 AFR_02965 6850507f78d8fcf79ffd15d977888d00 106 Gene3D G3DSA:3.40.50.2300 2 97 1.0E-22 T 12-10-2018 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 SUPERFAMILY SSF47413 1 47 3.84E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 Pfam PF13377 Periplasmic binding protein-like domain 155 322 2.7E-35 T 12-10-2018 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 Gene3D G3DSA:1.10.260.40 1 47 3.2E-16 T 12-10-2018 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 36 2.1E-8 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 Gene3D G3DSA:3.40.50.2300 48 301 3.3E-75 T 12-10-2018 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 SMART SM00354 1 59 2.3E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 Gene3D G3DSA:3.40.50.2300 146 280 3.3E-75 T 12-10-2018 AFR_39685 3027aa4b4ebb94697cbf26cabe0992a0 325 SUPERFAMILY SSF53822 50 322 3.44E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_22295 a95a2e6d2f78e517c8fa8dedc3f4b936 135 Gene3D G3DSA:3.30.1330.40 5 135 4.9E-30 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_22295 a95a2e6d2f78e517c8fa8dedc3f4b936 135 SUPERFAMILY SSF55298 16 135 2.36E-27 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_22295 a95a2e6d2f78e517c8fa8dedc3f4b936 135 Pfam PF01042 Endoribonuclease L-PSP 19 133 1.9E-19 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Gene3D G3DSA:3.30.420.140 334 461 1.2E-147 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 SUPERFAMILY SSF47781 480 568 1.78E-26 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Pfam PF00575 S1 RNA binding domain 659 730 6.6E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 SUPERFAMILY SSF50249 647 736 1.27E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Gene3D G3DSA:1.10.10.650 10 119 5.8E-38 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Gene3D G3DSA:1.10.3500.10 122 508 1.2E-147 T 12-10-2018 IPR023323 Tex-like domain superfamily AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Pfam PF09371 Tex-like protein N-terminal domain 19 203 3.6E-67 T 12-10-2018 IPR018974 Tex-like protein, N-terminal AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 SUPERFAMILY SSF53098 331 479 1.44E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 SUPERFAMILY SSF47781 570 641 3.11E-19 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 SMART SM00316 659 730 4.6E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Pfam PF16921 Tex protein YqgF-like domain 336 461 1.3E-50 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Gene3D G3DSA:1.10.150.310 509 640 1.5E-48 T 12-10-2018 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 SMART SM00732 335 434 8.4E-38 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 SUPERFAMILY SSF158832 12 330 9.94E-115 T 12-10-2018 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Pfam PF12836 Helix-hairpin-helix motif 501 565 3.8E-27 T 12-10-2018 AFR_27160 f8e82459bbb54bf57f7673306dab22e3 848 Gene3D G3DSA:2.40.50.140 641 735 4.5E-28 T 12-10-2018 AFR_04675 b808f5e1ca6ee44fe73102d0eb5a5303 204 Pfam PF05175 Methyltransferase small domain 31 197 1.3E-29 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFR_04675 b808f5e1ca6ee44fe73102d0eb5a5303 204 SUPERFAMILY SSF53335 21 198 4.59E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_04675 b808f5e1ca6ee44fe73102d0eb5a5303 204 Gene3D G3DSA:3.40.50.150 17 204 6.2E-42 T 12-10-2018 AFR_36000 6fcf478d3ab5a5a1b5835287db863660 140 SUPERFAMILY SSF47240 5 137 3.45E-32 T 12-10-2018 IPR009078 Ferritin-like superfamily AFR_36000 6fcf478d3ab5a5a1b5835287db863660 140 Pfam PF14530 Domain of unknown function (DUF4439) 5 138 1.4E-36 T 12-10-2018 IPR029447 Domain of unknown function DUF4439 AFR_36000 6fcf478d3ab5a5a1b5835287db863660 140 Gene3D G3DSA:1.20.1260.10 2 128 2.1E-35 T 12-10-2018 IPR012347 Ferritin-like AFR_05760 4bd49c6905731003a0cb26d8495eb263 424 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 5 423 2.2E-150 T 12-10-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 AFR_05760 4bd49c6905731003a0cb26d8495eb263 424 SUPERFAMILY SSF54909 51 414 7.87E-87 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_05760 4bd49c6905731003a0cb26d8495eb263 424 Pfam PF04261 Dyp-type peroxidase family 56 411 3.0E-103 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 AFR_05760 4bd49c6905731003a0cb26d8495eb263 424 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 56 411 7.4E-90 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 SUPERFAMILY SSF49452 126 222 1.67E-23 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 SUPERFAMILY SSF81296 365 470 1.01E-18 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Gene3D G3DSA:3.20.20.80 467 1017 2.4E-204 T 12-10-2018 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Pfam PF03714 Bacterial pullanase-associated domain 21 115 2.1E-17 T 12-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Pfam PF03714 Bacterial pullanase-associated domain 134 221 2.0E-17 T 12-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 SUPERFAMILY SSF81296 235 358 7.56E-20 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Gene3D G3DSA:2.60.40.1180 1018 1088 2.4E-16 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Gene3D G3DSA:2.60.40.1130 239 357 1.5E-24 T 12-10-2018 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 SUPERFAMILY SSF49452 19 120 2.52E-22 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 SUPERFAMILY SSF51011 989 1086 7.19E-22 T 12-10-2018 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Pfam PF11852 Domain of unknown function (DUF3372) 928 1086 1.1E-51 T 12-10-2018 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 367 452 5.5E-10 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Gene3D G3DSA:2.60.40.1110 17 119 3.8E-20 T 12-10-2018 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Gene3D G3DSA:2.60.40.1110 120 224 5.4E-21 T 12-10-2018 AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 SUPERFAMILY SSF51445 465 985 7.48E-120 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 Gene3D G3DSA:2.60.40.10 359 466 5.9E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_10940 6c8b3f762e9828db75e98e65bf908430 1090 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 240 1086 4.7E-300 T 12-10-2018 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 71 76 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 206 217 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site AFR_40095 4b85aab4c755807d99f9045084df1bff 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 61 76 1.9E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 205 217 1.9E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 116 130 1.9E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 Gene3D G3DSA:2.40.10.10 45 250 5.1E-74 T 12-10-2018 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 SMART SM00020 38 256 5.7E-70 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 Gene3D G3DSA:2.40.10.10 51 252 5.1E-74 T 12-10-2018 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 Pfam PF00089 Trypsin 39 256 3.3E-51 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_40095 4b85aab4c755807d99f9045084df1bff 265 SUPERFAMILY SSF50494 37 258 2.45E-61 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_37245 754394317dd66c1d3e29e5941a340416 489 Pfam PF00171 Aldehyde dehydrogenase family 11 453 8.2E-119 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_37245 754394317dd66c1d3e29e5941a340416 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 236 243 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_37245 754394317dd66c1d3e29e5941a340416 489 Gene3D G3DSA:3.40.605.10 11 450 5.8E-132 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_37245 754394317dd66c1d3e29e5941a340416 489 PIRSF PIRSF036492 24 489 3.8E-88 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 AFR_37245 754394317dd66c1d3e29e5941a340416 489 Gene3D G3DSA:3.40.309.10 244 427 5.8E-132 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_37245 754394317dd66c1d3e29e5941a340416 489 SUPERFAMILY SSF53720 7 456 4.19E-127 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_15480 d7867226b89c01319228d33af2b7f353 367 SUPERFAMILY SSF50370 237 366 1.81E-35 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_15480 d7867226b89c01319228d33af2b7f353 367 SMART SM00458 241 367 1.5E-26 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_15480 d7867226b89c01319228d33af2b7f353 367 Gene3D G3DSA:2.80.10.50 243 333 2.8E-25 T 12-10-2018 AFR_15480 d7867226b89c01319228d33af2b7f353 367 SUPERFAMILY SSF52266 28 226 2.54E-32 T 12-10-2018 AFR_15480 d7867226b89c01319228d33af2b7f353 367 Gene3D G3DSA:3.40.50.1110 33 236 3.2E-63 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_15480 d7867226b89c01319228d33af2b7f353 367 Pfam PF00652 Ricin-type beta-trefoil lectin domain 251 364 3.2E-25 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_15480 d7867226b89c01319228d33af2b7f353 367 Gene3D G3DSA:2.80.10.50 334 367 1.5E-10 T 12-10-2018 AFR_15480 d7867226b89c01319228d33af2b7f353 367 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 42 215 4.0E-20 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_03415 1097c6311f3698370aef0ebdf63bc069 408 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 19 377 1.5E-90 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_03415 1097c6311f3698370aef0ebdf63bc069 408 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 15 385 20.636 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_03415 1097c6311f3698370aef0ebdf63bc069 408 Pfam PF06965 Na+/H+ antiporter 1 17 379 7.9E-128 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFR_03415 1097c6311f3698370aef0ebdf63bc069 408 Gene3D G3DSA:1.20.1530.10 12 387 1.3E-132 T 12-10-2018 IPR023171 Na/H antiporter domain superfamily AFR_14420 ddf4e5efa55a83c82f7d0537797b3ae1 91 Gene3D G3DSA:3.10.20.30 2 80 7.1E-25 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_14420 ddf4e5efa55a83c82f7d0537797b3ae1 91 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 63 2.6E-6 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_14420 ddf4e5efa55a83c82f7d0537797b3ae1 91 SUPERFAMILY SSF54292 5 80 2.62E-20 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_14420 ddf4e5efa55a83c82f7d0537797b3ae1 91 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_07620 3443f564d7934f30b8ed786355ee8f45 519 SUPERFAMILY SSF56300 145 514 2.61E-33 T 12-10-2018 AFR_07620 3443f564d7934f30b8ed786355ee8f45 519 Pfam PF09423 PhoD-like phosphatase 155 499 1.2E-76 T 12-10-2018 IPR018946 Alkaline phosphatase D-related AFR_07620 3443f564d7934f30b8ed786355ee8f45 519 Gene3D G3DSA:2.60.40.380 43 142 7.1E-5 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 AFR_07620 3443f564d7934f30b8ed786355ee8f45 519 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 50 130 2.1E-17 T 12-10-2018 IPR032093 Phospholipase D, N-terminal AFR_07620 3443f564d7934f30b8ed786355ee8f45 519 Gene3D G3DSA:3.60.21.70 163 489 9.9E-60 T 12-10-2018 IPR038607 PhoD-like superfamily AFR_29520 0f75ef07493626e73732300d4df7264b 576 Pfam PF10592 AIPR protein 259 441 1.9E-44 T 12-10-2018 IPR018891 Abortive bacteriophage infection, resistance AFR_15115 527595ac70752523cd8b8e5b66eeb004 197 Pfam PF13460 NAD(P)H-binding 7 143 5.9E-10 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_15115 527595ac70752523cd8b8e5b66eeb004 197 Gene3D G3DSA:3.40.50.720 1 195 1.1E-32 T 12-10-2018 AFR_15115 527595ac70752523cd8b8e5b66eeb004 197 SUPERFAMILY SSF51735 1 195 1.33E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 530 546 9.1E-8 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 589 614 9.1E-8 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 558 574 9.1E-8 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 125 641 1.0E-81 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 Gene3D G3DSA:3.40.50.1000 331 609 8.9E-85 T 12-10-2018 IPR023214 HAD superfamily AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 Gene3D G3DSA:2.70.150.20 145 256 1.3E-34 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 Pfam PF00122 E1-E2 ATPase 152 329 1.1E-48 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 72 667 7.4E-165 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 558 577 3.9E-27 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 201 215 3.9E-27 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 581 593 3.9E-27 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 478 489 3.9E-27 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 350 364 3.9E-27 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 501 511 3.9E-27 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 90 665 2.9E-169 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 Pfam PF00702 haloacid dehalogenase-like hydrolase 346 572 1.7E-44 T 12-10-2018 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 SUPERFAMILY SSF56784 349 663 1.8E-52 T 12-10-2018 IPR036412 HAD-like superfamily AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 352 358 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 SUPERFAMILY SSF81653 154 251 7.85E-26 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 SUPERFAMILY SSF81665 115 342 1.18E-9 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFR_23185 a94dc54e38fdabfc7ec833389301525c 674 Gene3D G3DSA:3.40.1110.10 361 485 8.9E-85 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 Gene3D G3DSA:1.10.390.60 214 434 1.5E-41 T 12-10-2018 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 311 323 1.1E-14 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 189 204 1.1E-14 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 142 157 1.1E-14 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 292 307 1.1E-14 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 Gene3D G3DSA:2.60.40.1730 23 207 1.8E-24 T 12-10-2018 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 SUPERFAMILY SSF63737 15 205 2.48E-33 T 12-10-2018 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 Pfam PF01433 Peptidase family M1 domain 238 430 2.5E-30 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFR_15530 b2b7707ee743caa2a03651967140dd23 441 SUPERFAMILY SSF55486 213 439 1.1E-54 T 12-10-2018 AFR_10140 eaf446227e3353ede04bab0035b741fb 136 Gene3D G3DSA:3.30.1330.40 4 126 1.3E-26 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_10140 eaf446227e3353ede04bab0035b741fb 136 Pfam PF01042 Endoribonuclease L-PSP 18 126 8.5E-16 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_10140 eaf446227e3353ede04bab0035b741fb 136 SUPERFAMILY SSF55298 4 128 1.73E-26 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_19450 0affda772effad8475af43fb4b1b7af0 485 Gene3D G3DSA:1.20.1250.20 1 485 1.7E-129 T 12-10-2018 AFR_19450 0affda772effad8475af43fb4b1b7af0 485 SUPERFAMILY SSF103473 8 476 1.27E-30 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_19450 0affda772effad8475af43fb4b1b7af0 485 Pfam PF00854 POT family 88 452 1.0E-57 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 AFR_19450 0affda772effad8475af43fb4b1b7af0 485 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 153 165 - T 12-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 AFR_19450 0affda772effad8475af43fb4b1b7af0 485 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 7 481 1.0E-146 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 AFR_26840 39b4c604a8c2155f2b715de6e68e3349 282 SUPERFAMILY SSF53474 3 281 3.41E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_26840 39b4c604a8c2155f2b715de6e68e3349 282 Pfam PF00561 alpha/beta hydrolase fold 26 138 2.9E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_26840 39b4c604a8c2155f2b715de6e68e3349 282 Gene3D G3DSA:3.40.50.1820 1 280 3.5E-74 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_02875 16c88a25bfa76a17af6372e329e28c3f 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 267 8.6E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_02875 16c88a25bfa76a17af6372e329e28c3f 286 SUPERFAMILY SSF161098 17 286 5.05E-57 T 12-10-2018 IPR035906 MetI-like superfamily AFR_02875 16c88a25bfa76a17af6372e329e28c3f 286 Gene3D G3DSA:1.10.3720.10 11 274 2.6E-48 T 12-10-2018 IPR035906 MetI-like superfamily AFR_07255 e6c8c7576a2fea846235ebd177334d8c 193 Gene3D G3DSA:1.20.1290.10 40 179 4.7E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_07255 e6c8c7576a2fea846235ebd177334d8c 193 Pfam PF02627 Carboxymuconolactone decarboxylase family 58 125 2.3E-7 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_07255 e6c8c7576a2fea846235ebd177334d8c 193 SUPERFAMILY SSF69118 1 177 5.88E-33 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_29935 bf2577639e4a5c60e957ed9551a96989 585 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 535 1.4E-11 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFR_29935 bf2577639e4a5c60e957ed9551a96989 585 PIRSF PIRSF003128 1 582 1.0E-153 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFR_29935 bf2577639e4a5c60e957ed9551a96989 585 SUPERFAMILY SSF52540 4 533 1.14E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29935 bf2577639e4a5c60e957ed9551a96989 585 SUPERFAMILY SSF52540 1 223 4.4E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29935 bf2577639e4a5c60e957ed9551a96989 585 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 576 2.5E-163 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFR_29935 bf2577639e4a5c60e957ed9551a96989 585 Gene3D G3DSA:3.40.50.300 281 578 9.7E-51 T 12-10-2018 AFR_29935 bf2577639e4a5c60e957ed9551a96989 585 Gene3D G3DSA:3.40.50.300 1 270 3.7E-35 T 12-10-2018 AFR_31805 9258b2395ae6daa2562a974b877f1744 630 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 55 86 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_31805 9258b2395ae6daa2562a974b877f1744 630 Pfam PF04542 Sigma-70 region 2 33 99 5.6E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_31805 9258b2395ae6daa2562a974b877f1744 630 Pfam PF11790 Glycosyl hydrolase catalytic core 410 626 5.8E-55 T 12-10-2018 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain AFR_31805 9258b2395ae6daa2562a974b877f1744 630 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 189 2.7E-16 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_31805 9258b2395ae6daa2562a974b877f1744 630 SUPERFAMILY SSF88946 13 112 4.4E-20 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_31805 9258b2395ae6daa2562a974b877f1744 630 Gene3D G3DSA:3.20.20.80 456 630 9.7E-17 T 12-10-2018 AFR_31805 9258b2395ae6daa2562a974b877f1744 630 Gene3D G3DSA:1.10.1740.10 11 99 1.0E-19 T 12-10-2018 AFR_31805 9258b2395ae6daa2562a974b877f1744 630 SUPERFAMILY SSF51445 428 627 2.77E-23 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_31925 a3f5d5cf025ac002606a05a4a1e5b7b9 282 Pfam PF02146 Sir2 family 21 223 7.3E-41 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 AFR_31925 a3f5d5cf025ac002606a05a4a1e5b7b9 282 Gene3D G3DSA:3.40.50.1220 16 263 8.8E-68 T 12-10-2018 AFR_31925 a3f5d5cf025ac002606a05a4a1e5b7b9 282 SUPERFAMILY SSF52467 14 272 1.07E-66 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_31925 a3f5d5cf025ac002606a05a4a1e5b7b9 282 Gene3D G3DSA:3.30.1600.10 30 193 8.8E-68 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 SUPERFAMILY SSF47413 1 54 3.07E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 44 5.1E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 SMART SM00354 1 70 1.1E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 Gene3D G3DSA:3.40.50.2300 159 320 2.4E-67 T 12-10-2018 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 12-10-2018 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 Gene3D G3DSA:3.40.50.2300 61 315 2.4E-67 T 12-10-2018 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 Pfam PF13377 Periplasmic binding protein-like domain 167 322 2.4E-29 T 12-10-2018 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 Gene3D G3DSA:1.10.260.40 1 55 3.6E-17 T 12-10-2018 AFR_03210 8093b05586dbd6c00b80ce2e099e7fde 333 SUPERFAMILY SSF53822 57 309 1.35E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 Pfam PF00544 Pectate lyase 97 259 5.1E-38 T 12-10-2018 IPR002022 Pectate lyase AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 SMART SM00710 249 270 1600.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 SMART SM00710 147 169 3.6 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 SMART SM00710 123 145 7.9 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 SMART SM00710 226 248 5100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 SMART SM00656 60 265 6.7E-50 T 12-10-2018 IPR002022 Pectate lyase AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 SUPERFAMILY SSF51126 44 325 1.43E-76 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_17875 8f0ebdcc8275b9f1e98147738b5183ae 327 Gene3D G3DSA:2.160.20.10 42 327 1.4E-94 T 12-10-2018 IPR012334 Pectin lyase fold AFR_28515 84fc59ccf0258b6611ec57cb0e04beb8 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.3E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_28515 84fc59ccf0258b6611ec57cb0e04beb8 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.3E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_28515 84fc59ccf0258b6611ec57cb0e04beb8 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 3.3E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_28515 84fc59ccf0258b6611ec57cb0e04beb8 114 Gene3D G3DSA:1.10.10.10 4 111 1.1E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28515 84fc59ccf0258b6611ec57cb0e04beb8 114 SUPERFAMILY SSF46785 7 104 2.03E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_28515 84fc59ccf0258b6611ec57cb0e04beb8 114 Pfam PF12840 Helix-turn-helix domain 11 68 1.7E-14 T 12-10-2018 AFR_28515 84fc59ccf0258b6611ec57cb0e04beb8 114 SMART SM00418 11 89 1.9E-18 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_14260 9fb3aa78b210f02151e02c18893ce384 129 Gene3D G3DSA:3.30.530.20 1 127 6.6E-10 T 12-10-2018 IPR023393 START-like domain superfamily AFR_14260 9fb3aa78b210f02151e02c18893ce384 129 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 99 5.0E-7 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_14260 9fb3aa78b210f02151e02c18893ce384 129 SUPERFAMILY SSF55961 2 119 2.66E-13 T 12-10-2018 AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 SUPERFAMILY SSF55073 354 509 2.98E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 Pfam PF00563 EAL domain 523 759 3.9E-66 T 12-10-2018 IPR001633 EAL domain AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 Gene3D G3DSA:3.30.70.270 335 508 3.8E-53 T 12-10-2018 AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 Gene3D G3DSA:3.20.20.450 519 771 1.6E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 345 506 1.8E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 SMART SM00052 517 764 2.9E-97 T 12-10-2018 IPR001633 EAL domain AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 SMART SM00267 338 507 1.8E-54 T 12-10-2018 IPR000160 GGDEF domain AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 Pfam PF00990 Diguanylate cyclase, GGDEF domain 349 502 3.4E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_17380 4b6c039a13b65166ca7f9c4e8c680bb5 784 SUPERFAMILY SSF141868 523 770 1.44E-77 T 12-10-2018 IPR035919 EAL domain superfamily AFR_35185 b4a1c57c54d2e61eabc2d9d9bfb745f7 332 Pfam PF13365 Trypsin-like peptidase domain 168 305 4.9E-23 T 12-10-2018 AFR_35185 b4a1c57c54d2e61eabc2d9d9bfb745f7 332 PRINTS PR00834 HtrA/DegQ protease family signature 245 269 3.9E-16 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_35185 b4a1c57c54d2e61eabc2d9d9bfb745f7 332 PRINTS PR00834 HtrA/DegQ protease family signature 207 227 3.9E-16 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_35185 b4a1c57c54d2e61eabc2d9d9bfb745f7 332 PRINTS PR00834 HtrA/DegQ protease family signature 182 194 3.9E-16 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_35185 b4a1c57c54d2e61eabc2d9d9bfb745f7 332 PRINTS PR00834 HtrA/DegQ protease family signature 298 315 3.9E-16 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_35185 b4a1c57c54d2e61eabc2d9d9bfb745f7 332 SUPERFAMILY SSF50494 141 326 9.55E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_35185 b4a1c57c54d2e61eabc2d9d9bfb745f7 332 Gene3D G3DSA:2.40.10.120 127 331 5.4E-41 T 12-10-2018 AFR_00395 833857d7b6f15fa028379ab1a0dbb980 212 Pfam PF13620 Carboxypeptidase regulatory-like domain 36 125 4.7E-11 T 12-10-2018 AFR_00395 833857d7b6f15fa028379ab1a0dbb980 212 Gene3D G3DSA:2.60.40.1120 36 130 3.1E-7 T 12-10-2018 AFR_00395 833857d7b6f15fa028379ab1a0dbb980 212 SUPERFAMILY SSF49452 30 128 7.26E-12 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 SMART SM00387 475 587 1.5E-42 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 540 3.1E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 526 3.1E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 565 3.1E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 584 3.1E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 367 430 5.5E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 SUPERFAMILY SSF47384 349 431 4.12E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 SMART SM00388 366 430 6.2E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 Gene3D G3DSA:1.10.287.130 315 425 5.8E-19 T 12-10-2018 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 Gene3D G3DSA:3.30.565.10 429 586 2.4E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 SUPERFAMILY SSF55874 419 584 1.03E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 SMART SM00304 315 365 4.0E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 SUPERFAMILY SSF158472 316 359 2.09E-5 T 12-10-2018 AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 585 8.0E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_27665 ef52d9dc19c9769a769366373358f4e7 587 Pfam PF00672 HAMP domain 316 359 8.1E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_00950 d7571c8a874ac3accc3c8f6a60204c92 600 SUPERFAMILY SSF49899 351 596 7.08E-27 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_00950 d7571c8a874ac3accc3c8f6a60204c92 600 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 438 596 2.6E-15 T 12-10-2018 AFR_00950 d7571c8a874ac3accc3c8f6a60204c92 600 SUPERFAMILY SSF56300 47 282 1.0E-17 T 12-10-2018 AFR_00950 d7571c8a874ac3accc3c8f6a60204c92 600 Gene3D G3DSA:2.60.120.200 348 599 1.4E-20 T 12-10-2018 AFR_00950 d7571c8a874ac3accc3c8f6a60204c92 600 Gene3D G3DSA:3.60.21.10 25 265 4.8E-9 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_00950 d7571c8a874ac3accc3c8f6a60204c92 600 Pfam PF00149 Calcineurin-like phosphoesterase 46 206 5.8E-6 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_26670 65b381724a178726ed5127f26ebc42d9 202 SUPERFAMILY SSF46785 3 177 1.04E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26670 65b381724a178726ed5127f26ebc42d9 202 Pfam PF12840 Helix-turn-helix domain 4 56 4.4E-7 T 12-10-2018 AFR_26670 65b381724a178726ed5127f26ebc42d9 202 Gene3D G3DSA:1.10.10.10 1 85 2.4E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40985 4f18d5c714304b667635c8118c76d6c1 228 SUPERFAMILY SSF52172 3 183 8.19E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_40985 4f18d5c714304b667635c8118c76d6c1 228 SMART SM00862 148 224 4.6E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40985 4f18d5c714304b667635c8118c76d6c1 228 SMART SM00448 2 112 4.6E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40985 4f18d5c714304b667635c8118c76d6c1 228 Gene3D G3DSA:1.10.10.10 120 227 7.3E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40985 4f18d5c714304b667635c8118c76d6c1 228 Pfam PF00072 Response regulator receiver domain 4 112 3.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40985 4f18d5c714304b667635c8118c76d6c1 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 1.1E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40985 4f18d5c714304b667635c8118c76d6c1 228 Gene3D G3DSA:3.40.50.2300 2 119 4.8E-30 T 12-10-2018 AFR_38745 d968e7f5ee9db554769008e4a8e6a8d9 107 Pfam PF00037 4Fe-4S binding domain 34 55 1.3E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_38745 d968e7f5ee9db554769008e4a8e6a8d9 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.8E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFR_38745 d968e7f5ee9db554769008e4a8e6a8d9 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.8E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFR_38745 d968e7f5ee9db554769008e4a8e6a8d9 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.8E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFR_38745 d968e7f5ee9db554769008e4a8e6a8d9 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_38745 d968e7f5ee9db554769008e4a8e6a8d9 107 Gene3D G3DSA:3.30.70.20 2 106 1.6E-45 T 12-10-2018 AFR_38745 d968e7f5ee9db554769008e4a8e6a8d9 107 SUPERFAMILY SSF54862 3 84 1.66E-21 T 12-10-2018 AFR_40765 764b07741c4bb95be588a8b04a11da4e 363 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 47 362 1.7E-92 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFR_40765 764b07741c4bb95be588a8b04a11da4e 363 Pfam PF12849 PBP superfamily domain 39 332 1.1E-64 T 12-10-2018 IPR024370 PBP domain AFR_40765 764b07741c4bb95be588a8b04a11da4e 363 Gene3D G3DSA:3.40.190.10 51 349 4.2E-111 T 12-10-2018 AFR_40765 764b07741c4bb95be588a8b04a11da4e 363 PIRSF PIRSF002756 5 363 9.0E-124 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFR_40765 764b07741c4bb95be588a8b04a11da4e 363 Gene3D G3DSA:3.40.190.10 129 305 4.2E-111 T 12-10-2018 AFR_40765 764b07741c4bb95be588a8b04a11da4e 363 SUPERFAMILY SSF53850 46 363 1.09E-90 T 12-10-2018 AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 Gene3D G3DSA:3.20.20.450 400 650 1.3E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 Gene3D G3DSA:3.30.70.270 223 388 1.9E-51 T 12-10-2018 AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 225 380 6.9E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 SUPERFAMILY SSF55073 233 383 7.53E-44 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 SMART SM00052 397 642 2.7E-93 T 12-10-2018 IPR001633 EAL domain AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 SUPERFAMILY SSF141868 404 649 1.06E-83 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 Pfam PF00990 Diguanylate cyclase, GGDEF domain 228 379 9.1E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 SMART SM00267 217 387 3.5E-51 T 12-10-2018 IPR000160 GGDEF domain AFR_17800 08c82362a57b35a5916d03e062c8b9d8 675 Pfam PF00563 EAL domain 403 637 1.9E-68 T 12-10-2018 IPR001633 EAL domain AFR_27275 2cf05acb493946448fd1b21bb6fd21bd 158 Gene3D G3DSA:3.40.630.30 2 157 1.4E-27 T 12-10-2018 AFR_27275 2cf05acb493946448fd1b21bb6fd21bd 158 Pfam PF13302 Acetyltransferase (GNAT) domain 4 133 1.1E-18 T 12-10-2018 IPR000182 GNAT domain AFR_27275 2cf05acb493946448fd1b21bb6fd21bd 158 SUPERFAMILY SSF55729 3 146 2.38E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_15550 c0db124644f571be66d0b338666faa2e 253 Pfam PF12697 Alpha/beta hydrolase family 22 242 1.3E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15550 c0db124644f571be66d0b338666faa2e 253 SUPERFAMILY SSF53474 1 251 1.13E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15550 c0db124644f571be66d0b338666faa2e 253 Gene3D G3DSA:3.40.50.1820 1 252 1.3E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15550 c0db124644f571be66d0b338666faa2e 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 196 210 7.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15550 c0db124644f571be66d0b338666faa2e 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 7.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15550 c0db124644f571be66d0b338666faa2e 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 7.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_15550 c0db124644f571be66d0b338666faa2e 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 7.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18445 83822306ca31288f22a002c9bfee8a02 641 Gene3D G3DSA:1.10.3720.10 444 635 1.7E-31 T 12-10-2018 IPR035906 MetI-like superfamily AFR_18445 83822306ca31288f22a002c9bfee8a02 641 Gene3D G3DSA:1.10.3720.10 142 333 1.0E-29 T 12-10-2018 IPR035906 MetI-like superfamily AFR_18445 83822306ca31288f22a002c9bfee8a02 641 SUPERFAMILY SSF161098 145 328 2.09E-34 T 12-10-2018 IPR035906 MetI-like superfamily AFR_18445 83822306ca31288f22a002c9bfee8a02 641 SUPERFAMILY SSF161098 445 630 3.66E-34 T 12-10-2018 IPR035906 MetI-like superfamily AFR_18445 83822306ca31288f22a002c9bfee8a02 641 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 468 631 3.6E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_18445 83822306ca31288f22a002c9bfee8a02 641 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 167 324 6.5E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_31495 2c58a059f07864ed6d6b09ce66a07c7b 261 SUPERFAMILY SSF54001 86 225 1.32E-29 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_31495 2c58a059f07864ed6d6b09ce66a07c7b 261 Gene3D G3DSA:3.10.620.30 73 225 7.7E-61 T 12-10-2018 AFR_31495 2c58a059f07864ed6d6b09ce66a07c7b 261 SMART SM00460 145 205 3.4E-11 T 12-10-2018 IPR002931 Transglutaminase-like AFR_31495 2c58a059f07864ed6d6b09ce66a07c7b 261 Gene3D G3DSA:2.60.40.2250 10 229 7.7E-61 T 12-10-2018 AFR_31495 2c58a059f07864ed6d6b09ce66a07c7b 261 Pfam PF01841 Transglutaminase-like superfamily 103 203 1.5E-20 T 12-10-2018 IPR002931 Transglutaminase-like AFR_07595 02caf58b5dd603c05e956f69ff7d786b 235 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 120 226 5.2E-9 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_07595 02caf58b5dd603c05e956f69ff7d786b 235 Gene3D G3DSA:3.10.180.10 114 233 4.8E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_07595 02caf58b5dd603c05e956f69ff7d786b 235 SUPERFAMILY SSF54593 120 232 3.22E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_09495 663f2506cf40b2697488cffd77a1adf2 629 ProSitePatterns PS00211 ABC transporters family signature. 523 537 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_09495 663f2506cf40b2697488cffd77a1adf2 629 SMART SM00382 406 597 5.0E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_09495 663f2506cf40b2697488cffd77a1adf2 629 SUPERFAMILY SSF90123 45 344 9.94E-17 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_09495 663f2506cf40b2697488cffd77a1adf2 629 Pfam PF00005 ABC transporter 398 551 7.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_09495 663f2506cf40b2697488cffd77a1adf2 629 Gene3D G3DSA:3.40.50.300 375 628 2.3E-81 T 12-10-2018 AFR_09495 663f2506cf40b2697488cffd77a1adf2 629 Gene3D G3DSA:1.20.1560.10 41 347 3.6E-8 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_09495 663f2506cf40b2697488cffd77a1adf2 629 SUPERFAMILY SSF52540 373 621 5.52E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 SUPERFAMILY SSF52172 1 131 3.42E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 Pfam PF00072 Response regulator receiver domain 4 113 2.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 9.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 SMART SM00421 156 213 2.3E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 SMART SM00448 2 115 5.0E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 SUPERFAMILY SSF46894 150 219 5.1E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_34665 07f63fa62a1fa8eb880eb8875665a173 224 Gene3D G3DSA:3.40.50.12740 2 219 9.8E-67 T 12-10-2018 AFR_24790 a6c9e6eab1bc9a36c431a96f9e5e46b6 276 SUPERFAMILY SSF54001 115 254 2.24E-28 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_24790 a6c9e6eab1bc9a36c431a96f9e5e46b6 276 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 11 88 3.4E-10 T 12-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal AFR_24790 a6c9e6eab1bc9a36c431a96f9e5e46b6 276 Gene3D G3DSA:3.10.620.30 100 261 1.9E-40 T 12-10-2018 AFR_24790 a6c9e6eab1bc9a36c431a96f9e5e46b6 276 Pfam PF01841 Transglutaminase-like superfamily 127 215 6.0E-17 T 12-10-2018 IPR002931 Transglutaminase-like AFR_24790 a6c9e6eab1bc9a36c431a96f9e5e46b6 276 SMART SM00460 167 229 1.6E-12 T 12-10-2018 IPR002931 Transglutaminase-like AFR_29460 d2cb4135ed9e21bcdb30a57adbd5bb87 146 Gene3D G3DSA:3.10.450.50 2 143 2.6E-38 T 12-10-2018 AFR_29460 d2cb4135ed9e21bcdb30a57adbd5bb87 146 SUPERFAMILY SSF54427 8 145 6.97E-38 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_29460 d2cb4135ed9e21bcdb30a57adbd5bb87 146 Pfam PF07366 SnoaL-like polyketide cyclase 15 137 1.5E-30 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 AFR_11775 9b595f524d299d44a1eac7d343f6e1ea 480 Gene3D G3DSA:2.60.40.1180 36 474 1.1E-132 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_11775 9b595f524d299d44a1eac7d343f6e1ea 480 Gene3D G3DSA:3.20.20.80 43 374 1.1E-132 T 12-10-2018 AFR_11775 9b595f524d299d44a1eac7d343f6e1ea 480 SUPERFAMILY SSF51445 60 322 1.35E-18 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_20290 22b92cab69e8fdedead28a3a07db044a 457 Gene3D G3DSA:3.40.50.1820 151 450 2.3E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20290 22b92cab69e8fdedead28a3a07db044a 457 Pfam PF00561 alpha/beta hydrolase fold 175 282 1.3E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20290 22b92cab69e8fdedead28a3a07db044a 457 SUPERFAMILY SSF53474 134 451 8.44E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18420 5bf45ce352cd4d3d9eecf453f4a5bddb 153 Gene3D G3DSA:1.20.58.500 45 138 1.4E-14 T 12-10-2018 AFR_18420 5bf45ce352cd4d3d9eecf453f4a5bddb 153 Pfam PF03745 Domain of unknown function (DUF309) 48 106 2.5E-22 T 12-10-2018 IPR005500 Protein of unknown function DUF309 AFR_18420 5bf45ce352cd4d3d9eecf453f4a5bddb 153 SUPERFAMILY SSF140663 30 139 1.44E-29 T 12-10-2018 IPR023203 TTHA0068-like superfamily AFR_01650 7723c21f31aba5c37dacc4a2eb09c198 432 SUPERFAMILY SSF51905 15 405 1.12E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_01650 7723c21f31aba5c37dacc4a2eb09c198 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 318 2.2E-9 T 12-10-2018 AFR_01650 7723c21f31aba5c37dacc4a2eb09c198 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 165 180 2.2E-9 T 12-10-2018 AFR_01650 7723c21f31aba5c37dacc4a2eb09c198 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 2.2E-9 T 12-10-2018 AFR_01650 7723c21f31aba5c37dacc4a2eb09c198 432 Gene3D G3DSA:3.50.50.60 12 430 5.1E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_01650 7723c21f31aba5c37dacc4a2eb09c198 432 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 16 338 4.0E-73 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AFR_01650 7723c21f31aba5c37dacc4a2eb09c198 432 Pfam PF01494 FAD binding domain 14 184 1.5E-10 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 SUPERFAMILY SSF53271 582 715 3.87E-8 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 SMART SM00487 28 238 6.2E-21 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 SUPERFAMILY SSF52540 85 373 4.34E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 162 171 - T 12-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 Pfam PF00270 DEAD/DEAH box helicase 35 210 3.3E-14 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 Gene3D G3DSA:3.40.50.2020 581 717 2.0E-5 T 12-10-2018 AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 Pfam PF00271 Helicase conserved C-terminal domain 259 352 6.4E-13 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 SMART SM00490 272 353 2.6E-22 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_04065 13340082b5f9cbc1488c52dd4246abc8 718 Gene3D G3DSA:3.40.50.300 7 224 2.2E-52 T 12-10-2018 AFR_14055 360039b354550fbddbab3875c1281db6 524 SUPERFAMILY SSF103473 14 504 3.66E-76 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_14055 360039b354550fbddbab3875c1281db6 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 2.1E-7 T 12-10-2018 AFR_14055 360039b354550fbddbab3875c1281db6 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 2.1E-7 T 12-10-2018 AFR_14055 360039b354550fbddbab3875c1281db6 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 113 133 2.1E-7 T 12-10-2018 AFR_14055 360039b354550fbddbab3875c1281db6 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 208 226 2.1E-7 T 12-10-2018 AFR_14055 360039b354550fbddbab3875c1281db6 524 Pfam PF07690 Major Facilitator Superfamily 24 415 1.4E-55 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_14055 360039b354550fbddbab3875c1281db6 524 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 499 2.7E-135 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_14055 360039b354550fbddbab3875c1281db6 524 Gene3D G3DSA:1.20.1720.10 21 226 9.9E-52 T 12-10-2018 AFR_25535 43f377a553d0043b553701eb8943b524 376 SUPERFAMILY SSF53822 42 362 6.04E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_25535 43f377a553d0043b553701eb8943b524 376 Gene3D G3DSA:3.40.50.2300 44 350 1.1E-128 T 12-10-2018 AFR_25535 43f377a553d0043b553701eb8943b524 376 Gene3D G3DSA:3.40.50.2300 146 371 1.1E-128 T 12-10-2018 AFR_25535 43f377a553d0043b553701eb8943b524 376 Pfam PF13407 Periplasmic binding protein domain 44 329 8.2E-64 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_13330 e1cb80a0351de90142d79a466a8de945 371 Gene3D G3DSA:2.40.30.170 234 311 1.4E-9 T 12-10-2018 AFR_13330 e1cb80a0351de90142d79a466a8de945 371 Gene3D G3DSA:2.40.50.100 212 233 1.4E-9 T 12-10-2018 AFR_13330 e1cb80a0351de90142d79a466a8de945 371 Gene3D G3DSA:2.40.420.20 312 368 1.4E-9 T 12-10-2018 AFR_10405 8eab2fd39a92b56b161a0065704df316 299 Gene3D G3DSA:3.40.50.300 42 295 3.6E-67 T 12-10-2018 AFR_10405 8eab2fd39a92b56b161a0065704df316 299 SUPERFAMILY SSF52540 45 293 1.46E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10405 8eab2fd39a92b56b161a0065704df316 299 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 271 293 5.1E-13 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFR_10405 8eab2fd39a92b56b161a0065704df316 299 SMART SM00382 71 271 2.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10405 8eab2fd39a92b56b161a0065704df316 299 ProSitePatterns PS00211 ABC transporters family signature. 195 209 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10405 8eab2fd39a92b56b161a0065704df316 299 Pfam PF00005 ABC transporter 62 222 6.4E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_21800 99b60dae97b745e6d41eebd79edd2b3c 121 Gene3D G3DSA:3.10.129.10 2 121 1.5E-30 T 12-10-2018 AFR_21800 99b60dae97b745e6d41eebd79edd2b3c 121 SUPERFAMILY SSF54637 4 117 3.14E-15 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_21800 99b60dae97b745e6d41eebd79edd2b3c 121 Pfam PF03061 Thioesterase superfamily 25 80 5.6E-6 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFR_29525 625bea2e4f2921f933edc66df7562e7f 1047 SMART SM00382 58 329 15.0 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_29525 625bea2e4f2921f933edc66df7562e7f 1047 SMART SM00382 659 1003 0.0017 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_29525 625bea2e4f2921f933edc66df7562e7f 1047 Gene3D G3DSA:3.40.50.300 634 735 4.5E-9 T 12-10-2018 AFR_29525 625bea2e4f2921f933edc66df7562e7f 1047 Pfam PF01935 Domain of unknown function DUF87 641 892 5.5E-10 T 12-10-2018 IPR002789 Helicase HerA, central domain AFR_29525 625bea2e4f2921f933edc66df7562e7f 1047 SUPERFAMILY SSF52540 613 1013 1.1E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29525 625bea2e4f2921f933edc66df7562e7f 1047 Gene3D G3DSA:3.40.50.300 863 1024 5.6E-17 T 12-10-2018 AFR_28025 efe59c5d6f128d45aedc29320f0d65d7 210 SUPERFAMILY SSF46689 6 66 7.7E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_28025 efe59c5d6f128d45aedc29320f0d65d7 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 9.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28025 efe59c5d6f128d45aedc29320f0d65d7 210 Gene3D G3DSA:1.10.357.10 3 188 2.9E-45 T 12-10-2018 AFR_39345 701ca6942bdb72faf95993b16d7e481e 1138 SUPERFAMILY SSF56112 1 322 8.23E-61 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_39345 701ca6942bdb72faf95993b16d7e481e 1138 Gene3D G3DSA:1.10.510.10 76 255 1.9E-39 T 12-10-2018 AFR_39345 701ca6942bdb72faf95993b16d7e481e 1138 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 113 125 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_39345 701ca6942bdb72faf95993b16d7e481e 1138 Pfam PF00069 Protein kinase domain 2 240 1.0E-39 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_39345 701ca6942bdb72faf95993b16d7e481e 1138 Gene3D G3DSA:3.30.200.20 1 73 1.1E-18 T 12-10-2018 AFR_39345 701ca6942bdb72faf95993b16d7e481e 1138 SMART SM00220 1 244 3.2E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_05460 b232810bb882495cfa6672500f390d19 309 Pfam PF12706 Beta-lactamase superfamily domain 32 260 5.3E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_05460 b232810bb882495cfa6672500f390d19 309 Hamap MF_01818 Ribonuclease BN [rbn]. 2 293 31.211 T 12-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AFR_05460 b232810bb882495cfa6672500f390d19 309 SUPERFAMILY SSF56281 3 292 1.17E-63 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_05460 b232810bb882495cfa6672500f390d19 309 Gene3D G3DSA:3.60.15.10 3 293 2.9E-73 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_00920 055d13a4bd71b48392426498e919e2b6 126 Pfam PF13581 Histidine kinase-like ATPase domain 15 122 4.2E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_00920 055d13a4bd71b48392426498e919e2b6 126 Gene3D G3DSA:3.30.565.10 2 126 3.3E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_00920 055d13a4bd71b48392426498e919e2b6 126 SUPERFAMILY SSF55874 30 123 9.43E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12880 8af7acb31b5fc6dd01dad493ba170e7c 302 Gene3D G3DSA:1.10.1740.10 1 95 1.9E-16 T 12-10-2018 AFR_12880 8af7acb31b5fc6dd01dad493ba170e7c 302 Gene3D G3DSA:1.10.10.10 96 174 1.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12880 8af7acb31b5fc6dd01dad493ba170e7c 302 Pfam PF04542 Sigma-70 region 2 17 82 1.5E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_12880 8af7acb31b5fc6dd01dad493ba170e7c 302 SUPERFAMILY SSF88946 1 102 5.1E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_12880 8af7acb31b5fc6dd01dad493ba170e7c 302 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 167 1.2E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_12880 8af7acb31b5fc6dd01dad493ba170e7c 302 SUPERFAMILY SSF88659 101 169 8.07E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_12880 8af7acb31b5fc6dd01dad493ba170e7c 302 Pfam PF08281 Sigma-70, region 4 111 165 8.5E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 Gene3D G3DSA:3.40.50.12740 1 213 2.8E-66 T 12-10-2018 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 6.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 6.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 6.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 SUPERFAMILY SSF52172 1 132 3.56E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 SUPERFAMILY SSF46894 136 213 5.78E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 SMART SM00421 150 207 6.4E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 6.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 Pfam PF00072 Response regulator receiver domain 1 114 1.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_29980 3576ba9096bf446d4152d5b6c4884592 214 SMART SM00448 1 114 8.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_04145 cd8779e9eaa1293f00b8eb2194bc1b43 393 Gene3D G3DSA:3.40.50.720 14 264 1.3E-94 T 12-10-2018 AFR_04145 cd8779e9eaa1293f00b8eb2194bc1b43 393 Pfam PF00581 Rhodanese-like domain 291 384 8.0E-13 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_04145 cd8779e9eaa1293f00b8eb2194bc1b43 393 Gene3D G3DSA:3.40.250.10 272 390 1.7E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_04145 cd8779e9eaa1293f00b8eb2194bc1b43 393 Pfam PF00899 ThiF family 21 254 4.4E-65 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFR_04145 cd8779e9eaa1293f00b8eb2194bc1b43 393 SMART SM00450 291 388 1.2E-25 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_04145 cd8779e9eaa1293f00b8eb2194bc1b43 393 SUPERFAMILY SSF69572 7 360 9.42E-108 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFR_38545 949a5d4f0afd50b0f120b15240452af4 878 SUPERFAMILY SSF141072 644 755 7.46E-6 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_38545 949a5d4f0afd50b0f120b15240452af4 878 Gene3D G3DSA:3.40.50.1820 117 441 7.0E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_38545 949a5d4f0afd50b0f120b15240452af4 878 SUPERFAMILY SSF53474 110 396 4.02E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_26550 5f98b1af5316824bbe40bd5f97d237fa 185 Pfam PF13671 AAA domain 4 125 3.0E-8 T 12-10-2018 AFR_26550 5f98b1af5316824bbe40bd5f97d237fa 185 SUPERFAMILY SSF52540 4 126 1.47E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26550 5f98b1af5316824bbe40bd5f97d237fa 185 Gene3D G3DSA:3.40.50.300 2 181 5.2E-23 T 12-10-2018 AFR_07765 bafeda7fd0d854b6e18a707d99498b70 244 Pfam PF13460 NAD(P)H-binding 7 172 2.2E-10 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_07765 bafeda7fd0d854b6e18a707d99498b70 244 SUPERFAMILY SSF51735 1 203 5.75E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_07765 bafeda7fd0d854b6e18a707d99498b70 244 Gene3D G3DSA:3.40.50.720 2 241 1.8E-31 T 12-10-2018 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Pfam PF11799 impB/mucB/samB family C-terminal domain 229 339 1.1E-19 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Gene3D G3DSA:3.30.70.270 64 156 1.3E-29 T 12-10-2018 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 SUPERFAMILY SSF56672 1 226 2.4E-78 T 12-10-2018 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Gene3D G3DSA:3.30.1490.100 232 341 2.8E-26 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Gene3D G3DSA:1.10.150.20 159 228 5.5E-20 T 12-10-2018 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Pfam PF11798 IMS family HHH motif 160 188 3.5E-6 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Gene3D G3DSA:2.30.40.20 4 63 6.6E-29 T 12-10-2018 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 SUPERFAMILY SSF100879 231 329 3.92E-27 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Pfam PF00817 impB/mucB/samB family 1 144 4.0E-47 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_09910 a680ad17b1b9b177deb11b694b8f4962 401 Hamap MF_01113 DNA polymerase IV [dinB]. 1 343 33.548 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AFR_15515 6e8e5799e11d4a866e943fb2257648ee 198 Gene3D G3DSA:1.10.357.10 2 194 1.4E-37 T 12-10-2018 AFR_15515 6e8e5799e11d4a866e943fb2257648ee 198 SUPERFAMILY SSF48498 84 183 8.54E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_15515 6e8e5799e11d4a866e943fb2257648ee 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15515 6e8e5799e11d4a866e943fb2257648ee 198 SUPERFAMILY SSF46689 5 78 3.94E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15515 6e8e5799e11d4a866e943fb2257648ee 198 Pfam PF13305 WHG domain 91 171 5.5E-9 T 12-10-2018 IPR025996 WHG domain AFR_33630 64257363459e9d627d9916ebf4046536 344 ProSitePatterns PS00552 MerR-type HTH domain signature. 11 33 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33630 64257363459e9d627d9916ebf4046536 344 SUPERFAMILY SSF81606 127 340 1.96E-40 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_33630 64257363459e9d627d9916ebf4046536 344 SMART SM00422 8 78 2.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33630 64257363459e9d627d9916ebf4046536 344 SUPERFAMILY SSF46955 7 109 3.04E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_33630 64257363459e9d627d9916ebf4046536 344 Gene3D G3DSA:1.10.1660.10 4 114 2.0E-19 T 12-10-2018 AFR_33630 64257363459e9d627d9916ebf4046536 344 Pfam PF13411 MerR HTH family regulatory protein 9 76 3.0E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33630 64257363459e9d627d9916ebf4046536 344 SMART SM00332 118 339 5.8E-9 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_33630 64257363459e9d627d9916ebf4046536 344 Gene3D G3DSA:3.60.40.10 115 342 1.7E-42 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_33630 64257363459e9d627d9916ebf4046536 344 SMART SM00331 133 341 7.7E-22 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 Gene3D G3DSA:3.50.50.60 6 326 2.7E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 Gene3D G3DSA:3.30.9.50 39 261 2.7E-63 T 12-10-2018 AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.9E-13 T 12-10-2018 AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 2.9E-13 T 12-10-2018 AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 2.9E-13 T 12-10-2018 AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 2.9E-13 T 12-10-2018 AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 SUPERFAMILY SSF51905 2 349 2.68E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_10965 cf907d28cf44e873cfedd571e415a37c 379 Pfam PF01494 FAD binding domain 2 308 4.0E-15 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_04660 9dbc35c065d2abc013d6df07120e9ad3 194 Pfam PF01196 Ribosomal protein L17 20 116 8.7E-37 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04660 9dbc35c065d2abc013d6df07120e9ad3 194 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.21 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04660 9dbc35c065d2abc013d6df07120e9ad3 194 Gene3D G3DSA:3.90.1030.10 1 116 7.3E-44 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04660 9dbc35c065d2abc013d6df07120e9ad3 194 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04660 9dbc35c065d2abc013d6df07120e9ad3 194 SUPERFAMILY SSF64263 1 117 6.54E-46 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04660 9dbc35c065d2abc013d6df07120e9ad3 194 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 8.0E-40 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04230 6d2189c2b3659c6cd7379ddf893fe65a 364 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 96 151 2.0E-7 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04230 6d2189c2b3659c6cd7379ddf893fe65a 364 SUPERFAMILY SSF143243 40 170 3.53E-38 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04230 6d2189c2b3659c6cd7379ddf893fe65a 364 Gene3D G3DSA:3.30.460.80 14 141 2.0E-26 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04230 6d2189c2b3659c6cd7379ddf893fe65a 364 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 44 162 7.2E-36 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04230 6d2189c2b3659c6cd7379ddf893fe65a 364 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 123 144 - T 12-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_12220 f9e56c2483264563c5a4898d0940c2fc 383 Pfam PF13560 Helix-turn-helix domain 7 62 3.2E-6 T 12-10-2018 AFR_12220 f9e56c2483264563c5a4898d0940c2fc 383 SUPERFAMILY SSF49785 254 381 9.99E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_12220 f9e56c2483264563c5a4898d0940c2fc 383 Gene3D G3DSA:2.60.120.260 248 383 8.8E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 Gene3D G3DSA:1.10.287.950 223 538 8.7E-67 T 12-10-2018 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 SUPERFAMILY SSF58104 243 536 1.11E-64 T 12-10-2018 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 344 508 1.3E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 SMART SM00304 223 275 7.3E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 Pfam PF12729 Four helix bundle sensory module for signal transduction 27 191 2.6E-11 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 304 333 3.0E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 24 49 3.0E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 408 3.0E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 410 439 3.0E-21 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 Pfam PF00672 HAMP domain 224 271 1.1E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_31655 d0a7ebcc8df00bc14cc3f85c365d8dab 538 SMART SM00283 283 537 6.2E-55 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 Gene3D G3DSA:3.90.180.10 17 334 2.3E-98 T 12-10-2018 AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 SMART SM00829 11 337 4.0E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 SUPERFAMILY SSF51735 148 307 1.07E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 Gene3D G3DSA:3.40.50.720 157 288 2.3E-98 T 12-10-2018 AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 6.2E-29 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 Pfam PF00107 Zinc-binding dehydrogenase 184 303 1.1E-19 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_22945 b00d3e7ae6d7e185344e4778fc7fb710 339 SUPERFAMILY SSF50129 3 181 1.02E-49 T 12-10-2018 IPR011032 GroES-like superfamily AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 Gene3D G3DSA:3.40.50.12740 1 213 1.1E-66 T 12-10-2018 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 2.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 SUPERFAMILY SSF52172 1 132 1.71E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 SUPERFAMILY SSF46894 136 213 2.93E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 SMART SM00448 1 114 3.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 Pfam PF00072 Response regulator receiver domain 1 115 5.9E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_41185 d5fc5b4d6bab20bdf93f42b3d33639d8 240 SMART SM00421 150 207 4.0E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_06640 43877649c92aa33e605983bc9309c021 277 SUPERFAMILY SSF161098 22 266 6.45E-47 T 12-10-2018 IPR035906 MetI-like superfamily AFR_06640 43877649c92aa33e605983bc9309c021 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 259 1.1E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_06640 43877649c92aa33e605983bc9309c021 277 Gene3D G3DSA:1.10.3720.10 22 275 1.5E-43 T 12-10-2018 IPR035906 MetI-like superfamily AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 327 388 8.1E-6 T 12-10-2018 IPR001357 BRCT domain AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 Gene3D G3DSA:3.40.50.10190 320 397 1.5E-15 T 12-10-2018 IPR036420 BRCT domain superfamily AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 Pfam PF00929 Exonuclease 4 159 7.2E-21 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 Gene3D G3DSA:3.30.420.10 1 166 2.3E-40 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 SMART SM00479 1 168 2.6E-25 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 SUPERFAMILY SSF158682 202 308 5.76E-6 T 12-10-2018 IPR029024 TerB-like AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 SUPERFAMILY SSF52113 325 393 2.18E-10 T 12-10-2018 IPR036420 BRCT domain superfamily AFR_09740 8b47f77d9ecd006b39f3d19127f2498f 400 SUPERFAMILY SSF53098 1 165 2.28E-37 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_40040 551cfdb27697dcb6b5af1448308eefee 287 PIRSF PIRSF016184 1 282 2.2E-79 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFR_40040 551cfdb27697dcb6b5af1448308eefee 287 Gene3D G3DSA:3.10.310.10 117 271 4.1E-73 T 12-10-2018 AFR_40040 551cfdb27697dcb6b5af1448308eefee 287 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 282 5.9E-53 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFR_40040 551cfdb27697dcb6b5af1448308eefee 287 SUPERFAMILY SSF54506 3 281 7.56E-62 T 12-10-2018 AFR_40040 551cfdb27697dcb6b5af1448308eefee 287 Pfam PF02567 Phenazine biosynthesis-like protein 6 277 2.9E-48 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFR_40040 551cfdb27697dcb6b5af1448308eefee 287 Gene3D G3DSA:3.10.310.10 5 273 4.1E-73 T 12-10-2018 AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 286 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 Pfam PF12852 Cupin 2 176 4.2E-27 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 SUPERFAMILY SSF51215 35 175 2.48E-5 T 12-10-2018 IPR037923 Transcription regulator HTH-like AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 Pfam PF12833 Helix-turn-helix domain 213 291 2.1E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 SMART SM00342 207 290 3.3E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 SUPERFAMILY SSF46689 191 241 1.79E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 Gene3D G3DSA:1.10.10.60 187 292 2.9E-24 T 12-10-2018 AFR_14580 8b7f91b2950e72f36892d72e8eb3ed32 292 SUPERFAMILY SSF46689 243 291 4.48E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_05855 48f9466b775f36a6869379cd6c8b247f 400 Pfam PF01551 Peptidase family M23 293 391 5.3E-28 T 12-10-2018 IPR016047 Peptidase M23 AFR_05855 48f9466b775f36a6869379cd6c8b247f 400 SUPERFAMILY SSF51261 212 395 1.88E-52 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_05855 48f9466b775f36a6869379cd6c8b247f 400 Gene3D G3DSA:2.70.70.10 235 397 2.9E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_17290 73d1f27da058f8a31119c58886d1d19d 253 SUPERFAMILY SSF53474 2 249 1.63E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_17290 73d1f27da058f8a31119c58886d1d19d 253 Pfam PF12697 Alpha/beta hydrolase family 16 239 1.2E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_17290 73d1f27da058f8a31119c58886d1d19d 253 Gene3D G3DSA:3.40.50.1820 1 250 5.8E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13200 51eafd29e4939d9e8353edf466ed8bac 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 259 8.4E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_13200 51eafd29e4939d9e8353edf466ed8bac 274 SUPERFAMILY SSF161098 9 274 1.7E-64 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13200 51eafd29e4939d9e8353edf466ed8bac 274 Gene3D G3DSA:1.10.3720.10 4 265 5.1E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36690 b5ce05631618aa3bc7b84c4ebe5dfb3a 195 Pfam PF00694 Aconitase C-terminal domain 1 117 3.9E-25 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFR_36690 b5ce05631618aa3bc7b84c4ebe5dfb3a 195 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 38.732 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFR_36690 b5ce05631618aa3bc7b84c4ebe5dfb3a 195 SUPERFAMILY SSF52016 1 185 1.49E-51 T 12-10-2018 AFR_36690 b5ce05631618aa3bc7b84c4ebe5dfb3a 195 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 8.5E-59 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFR_36690 b5ce05631618aa3bc7b84c4ebe5dfb3a 195 Gene3D G3DSA:3.20.19.10 1 168 3.3E-65 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFR_16475 dd02cc5740f1019bc88f7b049e03e2ef 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_16475 dd02cc5740f1019bc88f7b049e03e2ef 199 Gene3D G3DSA:1.10.357.10 11 198 4.9E-36 T 12-10-2018 AFR_16475 dd02cc5740f1019bc88f7b049e03e2ef 199 SUPERFAMILY SSF46689 8 79 8.72E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_16475 dd02cc5740f1019bc88f7b049e03e2ef 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_16475 dd02cc5740f1019bc88f7b049e03e2ef 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_16475 dd02cc5740f1019bc88f7b049e03e2ef 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.9E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_16475 dd02cc5740f1019bc88f7b049e03e2ef 199 SUPERFAMILY SSF48498 86 196 9.34E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02365 cc65049a712cb25a71800a25a8a6e547 155 Pfam PF04542 Sigma-70 region 2 3 60 2.0E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02365 cc65049a712cb25a71800a25a8a6e547 155 Pfam PF04545 Sigma-70, region 4 92 141 1.9E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_02365 cc65049a712cb25a71800a25a8a6e547 155 Gene3D G3DSA:1.10.10.10 78 148 5.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02365 cc65049a712cb25a71800a25a8a6e547 155 SUPERFAMILY SSF88659 79 142 1.09E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_02365 cc65049a712cb25a71800a25a8a6e547 155 SUPERFAMILY SSF88946 2 73 1.18E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02365 cc65049a712cb25a71800a25a8a6e547 155 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 141 3.4E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02365 cc65049a712cb25a71800a25a8a6e547 155 Gene3D G3DSA:1.10.1740.10 1 58 3.1E-14 T 12-10-2018 AFR_37330 443188e08100c14bdbf780b120686eca 377 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 92 279 4.4E-36 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_37330 443188e08100c14bdbf780b120686eca 377 Gene3D G3DSA:1.10.260.150 59 365 1.3E-68 T 12-10-2018 AFR_12925 ca2ed1a04c6f80496d3b08a4b34b1897 71 Gene3D G3DSA:3.40.50.1820 17 69 1.1E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12925 ca2ed1a04c6f80496d3b08a4b34b1897 71 SUPERFAMILY SSF53474 20 65 9.1E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22585 ddf6d36e7b04b3c81c47468959c51272 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 5.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22585 ddf6d36e7b04b3c81c47468959c51272 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 5.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22585 ddf6d36e7b04b3c81c47468959c51272 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 5.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22585 ddf6d36e7b04b3c81c47468959c51272 322 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 5.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22585 ddf6d36e7b04b3c81c47468959c51272 322 Gene3D G3DSA:3.40.50.720 17 318 2.0E-71 T 12-10-2018 AFR_22585 ddf6d36e7b04b3c81c47468959c51272 322 Pfam PF00106 short chain dehydrogenase 26 231 3.4E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22585 ddf6d36e7b04b3c81c47468959c51272 322 SUPERFAMILY SSF51735 22 280 1.12E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 58 1.0E-16 T 12-10-2018 AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 Gene3D G3DSA:1.10.10.10 13 64 1.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 SUPERFAMILY SSF54909 72 155 2.55E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 SUPERFAMILY SSF46785 12 70 3.61E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 1.4E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 1.4E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 1.4E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 Pfam PF01037 Lrp/AsnC ligand binding domain 85 148 1.4E-10 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 SMART SM00344 14 119 1.1E-38 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_21855 2d7c9a957ce5a28259eabbf66b789ba5 162 Gene3D G3DSA:3.30.70.920 65 145 6.3E-18 T 12-10-2018 AFR_05415 c2f00da960f7a0cc3360dffbc530cdca 268 SUPERFAMILY SSF52266 59 256 1.02E-28 T 12-10-2018 AFR_05415 c2f00da960f7a0cc3360dffbc530cdca 268 Gene3D G3DSA:3.40.50.1110 48 255 4.3E-24 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_05415 c2f00da960f7a0cc3360dffbc530cdca 268 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 64 245 1.5E-19 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_15375 d584f48c6c1a6215d130cf3e27da5620 299 Gene3D G3DSA:3.40.50.300 1 223 3.3E-54 T 12-10-2018 AFR_15375 d584f48c6c1a6215d130cf3e27da5620 299 SMART SM00382 26 206 1.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_15375 d584f48c6c1a6215d130cf3e27da5620 299 Pfam PF00005 ABC transporter 18 156 4.2E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_15375 d584f48c6c1a6215d130cf3e27da5620 299 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_15375 d584f48c6c1a6215d130cf3e27da5620 299 SUPERFAMILY SSF52540 2 218 1.24E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13490 5bf7733ada8d22b1ed12aec97387bd89 200 SUPERFAMILY SSF46689 12 94 1.99E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13490 5bf7733ada8d22b1ed12aec97387bd89 200 Pfam PF13305 WHG domain 99 177 1.7E-10 T 12-10-2018 IPR025996 WHG domain AFR_13490 5bf7733ada8d22b1ed12aec97387bd89 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 71 2.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13490 5bf7733ada8d22b1ed12aec97387bd89 200 SUPERFAMILY SSF48498 96 181 6.78E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13490 5bf7733ada8d22b1ed12aec97387bd89 200 Gene3D G3DSA:1.10.357.10 9 198 4.7E-34 T 12-10-2018 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 5.4E-52 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 6.0E-32 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.301 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 Gene3D G3DSA:4.10.950.10 197 273 4.0E-30 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 2.9E-124 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 Gene3D G3DSA:2.40.50.140 1 115 6.7E-48 T 12-10-2018 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 SMART SM01382 125 253 2.2E-84 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 SMART SM01383 42 119 4.2E-42 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 Gene3D G3DSA:2.30.30.30 119 196 2.6E-29 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 SUPERFAMILY SSF50104 127 271 6.62E-53 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 PIRSF PIRSF002158 3 275 1.6E-91 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04520 aee2cddb75f8219fc43f1dcaa1dd6861 279 SUPERFAMILY SSF50249 2 126 3.77E-49 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_02960 7f13de5d0ddcda2b1ca04169bf1882e3 355 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 17 349 1.1E-141 T 12-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 AFR_02960 7f13de5d0ddcda2b1ca04169bf1882e3 355 Pfam PF02378 Phosphotransferase system, EIIC 28 285 7.7E-15 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 AFR_23695 7c2e262528e651b8dbf4d5f36bd735b6 263 SMART SM00346 13 101 1.1E-20 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_23695 7c2e262528e651b8dbf4d5f36bd735b6 263 SUPERFAMILY SSF46785 16 80 8.92E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23695 7c2e262528e651b8dbf4d5f36bd735b6 263 Pfam PF09339 IclR helix-turn-helix domain 16 63 3.8E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_23695 7c2e262528e651b8dbf4d5f36bd735b6 263 Gene3D G3DSA:3.30.450.40 88 259 1.1E-50 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_23695 7c2e262528e651b8dbf4d5f36bd735b6 263 Pfam PF01614 Bacterial transcriptional regulator 129 236 1.1E-31 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_23695 7c2e262528e651b8dbf4d5f36bd735b6 263 Gene3D G3DSA:1.10.10.10 3 78 4.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23695 7c2e262528e651b8dbf4d5f36bd735b6 263 SUPERFAMILY SSF55781 69 250 7.85E-45 T 12-10-2018 AFR_41605 7cf5d2df44421cdaabee43fa203f4665 410 SUPERFAMILY SSF56300 91 330 7.11E-33 T 12-10-2018 AFR_41605 7cf5d2df44421cdaabee43fa203f4665 410 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 92 328 3.2E-50 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA AFR_41605 7cf5d2df44421cdaabee43fa203f4665 410 SMART SM00854 92 331 3.1E-72 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA AFR_41605 7cf5d2df44421cdaabee43fa203f4665 410 Gene3D G3DSA:3.60.21.10 162 310 3.7E-5 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_22915 dbc18669a8e266883afd785f24218a5e 503 Gene3D G3DSA:1.20.1720.10 16 250 1.5E-40 T 12-10-2018 AFR_22915 dbc18669a8e266883afd785f24218a5e 503 SUPERFAMILY SSF103473 9 496 1.15E-63 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_22915 dbc18669a8e266883afd785f24218a5e 503 Pfam PF07690 Major Facilitator Superfamily 21 413 1.5E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_22915 dbc18669a8e266883afd785f24218a5e 503 Gene3D G3DSA:1.20.1250.20 272 491 5.6E-21 T 12-10-2018 AFR_33620 bd4578be8d1d57c7a8218f912add99d0 410 SUPERFAMILY SSF103473 8 398 4.97E-43 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_33620 bd4578be8d1d57c7a8218f912add99d0 410 Gene3D G3DSA:1.20.1250.20 5 392 2.5E-37 T 12-10-2018 AFR_33620 bd4578be8d1d57c7a8218f912add99d0 410 Pfam PF05977 Transmembrane secretion effector 2 398 1.5E-31 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 Pfam PF00990 Diguanylate cyclase, GGDEF domain 306 460 1.7E-47 T 12-10-2018 IPR000160 GGDEF domain AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 SMART SM00052 477 723 2.1E-107 T 12-10-2018 IPR001633 EAL domain AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 Pfam PF00563 EAL domain 485 718 1.7E-75 T 12-10-2018 IPR001633 EAL domain AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 Gene3D G3DSA:3.30.450.40 165 305 1.1E-8 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 SUPERFAMILY SSF141868 486 724 4.58E-82 T 12-10-2018 IPR035919 EAL domain superfamily AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 SUPERFAMILY SSF55073 311 468 1.8E-47 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 SUPERFAMILY SSF55781 158 298 6.54E-9 T 12-10-2018 AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 Gene3D G3DSA:3.30.70.270 306 479 5.3E-58 T 12-10-2018 AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 304 463 4.4E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 Gene3D G3DSA:3.20.20.450 480 727 1.2E-97 T 12-10-2018 IPR035919 EAL domain superfamily AFR_21645 be0f199c6135712c0f5e5502a5571dc4 728 SMART SM00267 294 466 6.9E-56 T 12-10-2018 IPR000160 GGDEF domain AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 349 364 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SUPERFAMILY SSF52113 621 691 1.12E-12 T 12-10-2018 IPR036420 BRCT domain superfamily AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SUPERFAMILY SSF50249 337 419 6.0E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Pfam PF14520 Helix-hairpin-helix domain 462 511 2.9E-5 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 340 416 8.6E-32 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Gene3D G3DSA:2.40.50.140 337 423 1.2E-31 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Gene3D G3DSA:1.10.150.20 519 597 6.2E-18 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Gene3D G3DSA:3.40.50.10190 608 692 2.3E-19 T 12-10-2018 IPR036420 BRCT domain superfamily AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SMART SM00532 26 462 2.4E-147 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Gene3D G3DSA:1.10.287.610 18 90 2.9E-9 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SUPERFAMILY SSF47781 423 595 1.48E-40 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Hamap MF_01588 DNA ligase [ligA]. 28 690 43.143 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Gene3D G3DSA:3.30.470.90 92 336 5.1E-75 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 135 164 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SMART SM00278 460 479 1100.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SMART SM00278 494 513 150.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SMART SM00278 558 577 73.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 37 684 1.6E-181 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 31 335 1.4E-77 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SMART SM00292 611 693 5.1E-4 T 12-10-2018 IPR001357 BRCT domain AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 PIRSF PIRSF001604 20 695 1.9E-184 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Gene3D G3DSA:1.10.150.20 448 518 3.6E-21 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Pfam PF12826 Helix-hairpin-helix motif 524 575 5.9E-13 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 SUPERFAMILY SSF56091 28 335 1.92E-80 T 12-10-2018 AFR_18045 889fcb5fc1b25ca3bbaa0af6a92a6c37 706 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 623 689 3.6E-6 T 12-10-2018 IPR001357 BRCT domain AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 SMART SM00052 490 731 7.1E-115 T 12-10-2018 IPR001633 EAL domain AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 Pfam PF00563 EAL domain 498 726 1.1E-75 T 12-10-2018 IPR001633 EAL domain AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 Gene3D G3DSA:3.30.70.270 324 493 1.1E-51 T 12-10-2018 AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 Gene3D G3DSA:3.20.20.450 494 742 2.4E-95 T 12-10-2018 IPR035919 EAL domain superfamily AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 SUPERFAMILY SSF141868 496 737 2.62E-87 T 12-10-2018 IPR035919 EAL domain superfamily AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 SMART SM00267 313 480 4.2E-54 T 12-10-2018 IPR000160 GGDEF domain AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 SUPERFAMILY SSF55073 328 482 7.06E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 Pfam PF00990 Diguanylate cyclase, GGDEF domain 325 474 1.1E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_22770 a7931a6e63f1829ab1bef4d710dec972 743 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 324 477 5.0E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_15060 99c690390d202df834ba8a4843034b20 474 Gene3D G3DSA:2.60.120.200 46 202 1.2E-12 T 12-10-2018 AFR_24395 4570f74de2c883ba03fa65599cc92e8e 352 Pfam PF13416 Bacterial extracellular solute-binding protein 56 314 6.2E-24 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_24395 4570f74de2c883ba03fa65599cc92e8e 352 Gene3D G3DSA:3.40.190.10 45 315 4.2E-94 T 12-10-2018 AFR_24395 4570f74de2c883ba03fa65599cc92e8e 352 Gene3D G3DSA:3.40.190.10 141 329 4.2E-94 T 12-10-2018 AFR_24395 4570f74de2c883ba03fa65599cc92e8e 352 SUPERFAMILY SSF53850 40 344 8.89E-65 T 12-10-2018 AFR_24395 4570f74de2c883ba03fa65599cc92e8e 352 PIRSF PIRSF002825 5 346 3.3E-65 T 12-10-2018 IPR026045 Ferric binding protein AFR_00730 b7ce0338598ad415dc1874d8d914acee 686 Pfam PF13620 Carboxypeptidase regulatory-like domain 112 196 9.7E-9 T 12-10-2018 AFR_00730 b7ce0338598ad415dc1874d8d914acee 686 Gene3D G3DSA:2.60.40.1120 113 197 1.7E-7 T 12-10-2018 AFR_00730 b7ce0338598ad415dc1874d8d914acee 686 SUPERFAMILY SSF49464 113 196 1.73E-7 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFR_03615 8e9659594353edab4495fe28959f7505 311 Gene3D G3DSA:3.80.10.10 36 311 2.6E-83 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily AFR_03615 8e9659594353edab4495fe28959f7505 311 SUPERFAMILY SSF52047 102 284 1.44E-12 T 12-10-2018 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 Gene3D G3DSA:3.40.50.300 267 536 5.0E-86 T 12-10-2018 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 Gene3D G3DSA:3.40.50.300 1 266 2.8E-79 T 12-10-2018 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 ProSitePatterns PS00211 ABC transporters family signature. 412 426 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 SUPERFAMILY SSF52540 268 511 1.92E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 Pfam PF00005 ABC transporter 20 175 1.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 SUPERFAMILY SSF52540 3 247 8.49E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 492 523 2.7E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 266 2.2E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 SMART SM00382 304 489 1.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 SMART SM00382 28 225 9.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_24230 60d3943bdadbfbb6daf000a09a5f4dde 537 Pfam PF00005 ABC transporter 296 439 3.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 SUPERFAMILY SSF52833 5 107 3.41E-36 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 PIRSF PIRSF000077 2 107 8.2E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 Pfam PF00085 Thioredoxin 5 104 4.2E-32 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 7.6E-36 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 PRINTS PR00421 Thioredoxin family signature 23 31 4.6E-7 T 12-10-2018 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 PRINTS PR00421 Thioredoxin family signature 31 40 4.6E-7 T 12-10-2018 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 PRINTS PR00421 Thioredoxin family signature 71 82 4.6E-7 T 12-10-2018 AFR_42935 e3bdba755918a2a7ca99b58573702a84 107 Gene3D G3DSA:3.40.30.10 2 107 1.1E-34 T 12-10-2018 AFR_37915 3500640480e8578e39168fa407b76838 401 Gene3D G3DSA:3.40.50.300 4 222 5.3E-64 T 12-10-2018 AFR_37915 3500640480e8578e39168fa407b76838 401 Pfam PF00005 ABC transporter 21 162 4.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_37915 3500640480e8578e39168fa407b76838 401 SUPERFAMILY SSF52540 4 241 6.65E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37915 3500640480e8578e39168fa407b76838 401 SMART SM00382 29 212 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37915 3500640480e8578e39168fa407b76838 401 SUPERFAMILY SSF50331 237 396 1.82E-6 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_37915 3500640480e8578e39168fa407b76838 401 Gene3D G3DSA:2.40.50.940 223 289 1.3E-9 T 12-10-2018 AFR_37915 3500640480e8578e39168fa407b76838 401 Gene3D G3DSA:2.40.50.140 290 322 1.3E-9 T 12-10-2018 AFR_37915 3500640480e8578e39168fa407b76838 401 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_23490 438a07e642517c5e29f046f4e8a5a5f1 201 Gene3D G3DSA:3.90.550.10 3 198 2.0E-55 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23490 438a07e642517c5e29f046f4e8a5a5f1 201 SUPERFAMILY SSF53448 7 190 1.38E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23490 438a07e642517c5e29f046f4e8a5a5f1 201 TIGRFAM TIGR04282 glyco_like_cofC: transferase 1, rSAM/selenodomain-associated 5 182 1.6E-40 T 12-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated AFR_23490 438a07e642517c5e29f046f4e8a5a5f1 201 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 52 150 2.7E-28 T 12-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated AFR_07560 5684a94d2e89e4222dc822b79f3b16fc 265 Pfam PF00795 Carbon-nitrogen hydrolase 2 254 1.9E-62 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFR_07560 5684a94d2e89e4222dc822b79f3b16fc 265 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 147 167 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site AFR_07560 5684a94d2e89e4222dc822b79f3b16fc 265 SUPERFAMILY SSF56317 1 263 4.06E-85 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_07560 5684a94d2e89e4222dc822b79f3b16fc 265 Gene3D G3DSA:3.60.110.10 1 265 3.5E-97 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 84 95 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 3 129 4.0E-51 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 SUPERFAMILY SSF54686 11 138 6.28E-52 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 Pfam PF00252 Ribosomal protein L16p/L10e 11 134 6.5E-45 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 136 34.833 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 Gene3D G3DSA:3.90.1170.10 3 141 1.5E-47 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 PRINTS PR00060 Ribosomal protein L16 signature 90 119 1.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 PRINTS PR00060 Ribosomal protein L16 signature 26 38 1.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 PRINTS PR00060 Ribosomal protein L16 signature 44 55 1.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04540 fa7534ece22b5cd733d45dd79e7080a4 141 PRINTS PR00060 Ribosomal protein L16 signature 60 89 1.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_27310 d7331fa5c63d2372466cb187646b1031 462 Pfam PF07690 Major Facilitator Superfamily 44 401 6.1E-27 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_27310 d7331fa5c63d2372466cb187646b1031 462 SUPERFAMILY SSF103473 12 454 7.32E-44 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_27310 d7331fa5c63d2372466cb187646b1031 462 Gene3D G3DSA:1.20.1250.20 15 447 8.5E-34 T 12-10-2018 AFR_39510 e3c3e389f6a66faf8b82714daed664a4 284 Gene3D G3DSA:3.40.605.10 24 283 1.2E-43 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_39510 e3c3e389f6a66faf8b82714daed664a4 284 SUPERFAMILY SSF53720 21 251 1.57E-36 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_39510 e3c3e389f6a66faf8b82714daed664a4 284 Pfam PF00171 Aldehyde dehydrogenase family 48 250 1.6E-30 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 201 213 1.4E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 122 136 1.4E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 65 80 1.4E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 Gene3D G3DSA:2.40.10.10 123 256 8.8E-14 T 12-10-2018 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 SUPERFAMILY SSF50494 28 256 6.99E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 Gene3D G3DSA:2.40.10.10 30 122 3.7E-11 T 12-10-2018 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 SMART SM00020 29 251 4.4E-16 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 75 80 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_18715 eecf3fcd655f1fdb73c5d7f07e8d41ef 337 Pfam PF00089 Trypsin 33 251 1.3E-22 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_35025 f51be023f6e340df868c081a169cc240 498 Pfam PF13286 Phosphohydrolase-associated domain 383 482 6.9E-8 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain AFR_35025 f51be023f6e340df868c081a169cc240 498 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 23 484 2.3E-66 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 AFR_35025 f51be023f6e340df868c081a169cc240 498 SUPERFAMILY SSF109604 23 336 5.65E-50 T 12-10-2018 AFR_35025 f51be023f6e340df868c081a169cc240 498 SMART SM00471 56 258 5.0E-12 T 12-10-2018 IPR003607 HD/PDEase domain AFR_35025 f51be023f6e340df868c081a169cc240 498 Pfam PF01966 HD domain 60 140 6.2E-12 T 12-10-2018 IPR006674 HD domain AFR_13745 ee11fdd7998765e7982ff6dc3bb74c5c 385 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 121 376 3.1E-12 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFR_13745 ee11fdd7998765e7982ff6dc3bb74c5c 385 SUPERFAMILY SSF56529 113 377 2.75E-16 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_36630 9549520ddb11bdf15634afd528d7f442 298 SMART SM00382 26 204 3.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36630 9549520ddb11bdf15634afd528d7f442 298 Gene3D G3DSA:3.40.50.300 1 224 3.8E-39 T 12-10-2018 AFR_36630 9549520ddb11bdf15634afd528d7f442 298 SUPERFAMILY SSF52540 2 216 4.97E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36630 9549520ddb11bdf15634afd528d7f442 298 Pfam PF00005 ABC transporter 17 152 1.3E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SUPERFAMILY SSF52172 885 1004 1.18E-25 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Gene3D G3DSA:3.30.450.20 477 594 3.1E-26 T 12-10-2018 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 356 477 1.5E-27 T 12-10-2018 IPR000014 PAS domain AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 474 599 3.6E-22 T 12-10-2018 IPR000014 PAS domain AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Pfam PF00512 His Kinase A (phospho-acceptor) domain 624 695 1.1E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Gene3D G3DSA:3.40.50.2300 883 1016 2.0E-24 T 12-10-2018 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SUPERFAMILY SSF55874 688 858 3.27E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SUPERFAMILY SSF55785 352 470 8.38E-25 T 12-10-2018 IPR035965 PAS domain superfamily AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SMART SM00388 624 697 2.6E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SUPERFAMILY SSF55785 488 601 1.66E-22 T 12-10-2018 IPR035965 PAS domain superfamily AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SMART SM00091 358 424 3.6E-11 T 12-10-2018 IPR000014 PAS domain AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SMART SM00091 477 543 2.9E-10 T 12-10-2018 IPR000014 PAS domain AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Gene3D G3DSA:1.10.287.130 616 695 9.1E-18 T 12-10-2018 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 PRINTS PR00344 Bacterial sensor protein C-terminal signature 789 803 3.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 857 3.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 PRINTS PR00344 Bacterial sensor protein C-terminal signature 820 838 3.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 PRINTS PR00344 Bacterial sensor protein C-terminal signature 807 817 3.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 739 858 1.3E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SMART SM00448 885 998 1.5E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Gene3D G3DSA:3.30.450.20 350 476 4.8E-31 T 12-10-2018 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SMART SM00387 738 860 9.7E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Gene3D G3DSA:3.30.565.10 698 864 1.1E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SUPERFAMILY SSF47384 616 695 1.06E-8 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SMART SM00086 430 472 2.0E-6 T 12-10-2018 IPR001610 PAC motif AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 SMART SM00086 553 593 260.0 T 12-10-2018 IPR001610 PAC motif AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Pfam PF13426 PAS domain 377 471 1.1E-17 T 12-10-2018 IPR000014 PAS domain AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Pfam PF13426 PAS domain 487 592 2.9E-11 T 12-10-2018 IPR000014 PAS domain AFR_28705 02b63387d5e4c2962d52088aad90edff 1025 Pfam PF00072 Response regulator receiver domain 887 997 2.0E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_16690 5d122c28ffff8d3295679b664fbc1ac6 377 Pfam PF01594 AI-2E family transporter 25 346 2.2E-58 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFR_19910 1fb715b6275aa591b36406e7a3d5b6ee 237 SUPERFAMILY SSF52540 4 219 3.42E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19910 1fb715b6275aa591b36406e7a3d5b6ee 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_19910 1fb715b6275aa591b36406e7a3d5b6ee 237 Pfam PF00005 ABC transporter 19 165 2.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_19910 1fb715b6275aa591b36406e7a3d5b6ee 237 SMART SM00382 28 221 7.8E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_19910 1fb715b6275aa591b36406e7a3d5b6ee 237 Gene3D G3DSA:3.40.50.300 2 232 1.2E-70 T 12-10-2018 AFR_21050 0dbd5151d2b1eeca6fc568e445e6eef6 464 SUPERFAMILY SSF52540 41 337 2.6E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21050 0dbd5151d2b1eeca6fc568e445e6eef6 464 Gene3D G3DSA:3.40.50.300 39 250 6.1E-27 T 12-10-2018 AFR_19255 58ecc5430bdf21c1268f540634c63788 265 Pfam PF09339 IclR helix-turn-helix domain 17 68 4.2E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_19255 58ecc5430bdf21c1268f540634c63788 265 Pfam PF01614 Bacterial transcriptional regulator 130 255 9.8E-37 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_19255 58ecc5430bdf21c1268f540634c63788 265 Gene3D G3DSA:1.10.10.10 3 81 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19255 58ecc5430bdf21c1268f540634c63788 265 SUPERFAMILY SSF55781 79 258 9.16E-51 T 12-10-2018 AFR_19255 58ecc5430bdf21c1268f540634c63788 265 SMART SM00346 15 103 1.6E-33 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_19255 58ecc5430bdf21c1268f540634c63788 265 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 12 258 1.2E-100 T 12-10-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 AFR_19255 58ecc5430bdf21c1268f540634c63788 265 Gene3D G3DSA:3.30.450.40 82 262 1.3E-61 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_19255 58ecc5430bdf21c1268f540634c63788 265 SUPERFAMILY SSF46785 15 87 1.39E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30515 9d1be873383686445bc2d41ec4377461 200 SUPERFAMILY SSF63380 1 88 6.55E-22 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_30515 9d1be873383686445bc2d41ec4377461 200 SUPERFAMILY SSF63380 93 195 1.36E-33 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_30515 9d1be873383686445bc2d41ec4377461 200 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 194 9.7E-62 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30515 9d1be873383686445bc2d41ec4377461 200 PIRSF PIRSF000498 1 199 2.9E-71 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30515 9d1be873383686445bc2d41ec4377461 200 Pfam PF00677 Lumazine binding domain 100 184 3.9E-26 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30515 9d1be873383686445bc2d41ec4377461 200 Pfam PF00677 Lumazine binding domain 3 87 2.5E-20 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30515 9d1be873383686445bc2d41ec4377461 200 Gene3D G3DSA:2.40.30.20 102 199 4.0E-36 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_30515 9d1be873383686445bc2d41ec4377461 200 Gene3D G3DSA:2.40.30.20 1 88 2.4E-25 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_27985 700fa62ca7bc2863253b564280de89c3 192 SMART SM01012 127 182 5.3E-7 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_27985 700fa62ca7bc2863253b564280de89c3 192 Pfam PF03861 ANTAR domain 132 182 3.9E-7 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_22580 7631bd39eae26321e03789ce602c15e1 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.8E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22580 7631bd39eae26321e03789ce602c15e1 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.8E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22580 7631bd39eae26321e03789ce602c15e1 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 6.6E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22580 7631bd39eae26321e03789ce602c15e1 186 Gene3D G3DSA:1.10.357.10 4 184 8.9E-23 T 12-10-2018 AFR_22580 7631bd39eae26321e03789ce602c15e1 186 SUPERFAMILY SSF46689 6 80 7.98E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03735 f6b67d57c1480fd97c6c0eef72ca67a8 328 SUPERFAMILY SSF46689 208 259 7.69E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03735 f6b67d57c1480fd97c6c0eef72ca67a8 328 Gene3D G3DSA:1.10.10.60 211 316 5.6E-25 T 12-10-2018 AFR_03735 f6b67d57c1480fd97c6c0eef72ca67a8 328 Pfam PF12852 Cupin 3 193 1.7E-47 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFR_03735 f6b67d57c1480fd97c6c0eef72ca67a8 328 SUPERFAMILY SSF46689 261 310 1.15E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03735 f6b67d57c1480fd97c6c0eef72ca67a8 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 304 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_03735 f6b67d57c1480fd97c6c0eef72ca67a8 328 Pfam PF12833 Helix-turn-helix domain 231 310 5.3E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_03735 f6b67d57c1480fd97c6c0eef72ca67a8 328 SMART SM00342 225 308 8.3E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_42150 a5a238aad4cb9775c7aa1ef6d0e2fa7a 293 Pfam PF00005 ABC transporter 20 155 2.4E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_42150 a5a238aad4cb9775c7aa1ef6d0e2fa7a 293 SMART SM00382 29 204 2.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_42150 a5a238aad4cb9775c7aa1ef6d0e2fa7a 293 SUPERFAMILY SSF52540 5 218 6.3E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42150 a5a238aad4cb9775c7aa1ef6d0e2fa7a 293 Gene3D G3DSA:3.40.50.300 2 230 3.8E-56 T 12-10-2018 AFR_39225 30ae07e9c6baa2c4f4635f4b277bfa21 341 PIRSF PIRSF004532 10 330 4.7E-144 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFR_39225 30ae07e9c6baa2c4f4635f4b277bfa21 341 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 11 323 4.5E-109 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFR_39225 30ae07e9c6baa2c4f4635f4b277bfa21 341 Gene3D G3DSA:3.30.540.10 16 319 2.5E-130 T 12-10-2018 AFR_39225 30ae07e9c6baa2c4f4635f4b277bfa21 341 SUPERFAMILY SSF56655 10 322 8.75E-110 T 12-10-2018 AFR_39225 30ae07e9c6baa2c4f4635f4b277bfa21 341 Gene3D G3DSA:3.40.190.90 132 293 2.5E-130 T 12-10-2018 AFR_39225 30ae07e9c6baa2c4f4635f4b277bfa21 341 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 12 319 5.6E-140 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFR_06920 cce711df9d7efdecadea06d99a5cc62a 179 Pfam PF00583 Acetyltransferase (GNAT) family 41 155 9.9E-11 T 12-10-2018 IPR000182 GNAT domain AFR_06920 cce711df9d7efdecadea06d99a5cc62a 179 Gene3D G3DSA:3.40.630.30 1 179 1.2E-33 T 12-10-2018 AFR_06920 cce711df9d7efdecadea06d99a5cc62a 179 SUPERFAMILY SSF55729 1 178 7.09E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_32970 4637bdbc48411ab471b4c5af5a3267d4 123 Gene3D G3DSA:3.90.79.10 1 121 2.3E-27 T 12-10-2018 AFR_32970 4637bdbc48411ab471b4c5af5a3267d4 123 PRINTS PR00502 NUDIX hydrolase family signature 31 46 9.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_32970 4637bdbc48411ab471b4c5af5a3267d4 123 PRINTS PR00502 NUDIX hydrolase family signature 17 31 9.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_32970 4637bdbc48411ab471b4c5af5a3267d4 123 Pfam PF00293 NUDIX domain 4 107 7.3E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_32970 4637bdbc48411ab471b4c5af5a3267d4 123 SUPERFAMILY SSF55811 3 106 4.2E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_32970 4637bdbc48411ab471b4c5af5a3267d4 123 ProSitePatterns PS00893 Nudix box signature. 22 43 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_31280 c15e07757093738fb77ac9181ddcef1c 178 Gene3D G3DSA:3.40.630.30 1 171 1.4E-44 T 12-10-2018 AFR_31280 c15e07757093738fb77ac9181ddcef1c 178 Pfam PF13302 Acetyltransferase (GNAT) domain 8 150 3.7E-32 T 12-10-2018 IPR000182 GNAT domain AFR_31280 c15e07757093738fb77ac9181ddcef1c 178 SUPERFAMILY SSF55729 1 153 1.77E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_32095 7483f8742d7de43fa2a237cd3b458b6d 444 Gene3D G3DSA:2.130.10.10 18 316 1.4E-16 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_32095 7483f8742d7de43fa2a237cd3b458b6d 444 Pfam PF13360 PQQ-like domain 85 328 1.8E-10 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_32095 7483f8742d7de43fa2a237cd3b458b6d 444 SUPERFAMILY SSF50998 54 291 7.06E-18 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_32095 7483f8742d7de43fa2a237cd3b458b6d 444 SUPERFAMILY SSF50998 216 442 7.69E-8 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_15090 387bdfc141157bcda78f02b25e0ad76d 107 Pfam PF03795 YCII-related domain 1 105 1.0E-12 T 12-10-2018 IPR005545 YCII-related AFR_15090 387bdfc141157bcda78f02b25e0ad76d 107 SUPERFAMILY SSF54909 1 106 5.63E-24 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_15090 387bdfc141157bcda78f02b25e0ad76d 107 Gene3D G3DSA:3.30.70.1060 1 107 2.6E-30 T 12-10-2018 AFR_01890 1bc88bd3e2c3067e066a237b38a95886 774 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 8 720 24.462 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFR_01890 1bc88bd3e2c3067e066a237b38a95886 774 Pfam PF03030 Inorganic H+ pyrophosphatase 19 715 1.4E-240 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFR_01890 1bc88bd3e2c3067e066a237b38a95886 774 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 11 721 7.9E-204 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFR_01890 1bc88bd3e2c3067e066a237b38a95886 774 PIRSF PIRSF001265 3 728 3.0E-250 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 SUPERFAMILY SSF56059 84 329 5.3E-60 T 12-10-2018 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 SUPERFAMILY SSF51230 571 640 6.81E-21 T 12-10-2018 IPR011053 Single hybrid motif AFR_28390 67325a119bd7f9069b67e48511f843dd 645 Gene3D G3DSA:2.40.50.100 575 644 9.1E-24 T 12-10-2018 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 Pfam PF00364 Biotin-requiring enzyme 577 639 6.0E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_28390 67325a119bd7f9069b67e48511f843dd 645 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 111 3.9E-39 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 SUPERFAMILY SSF51246 324 443 2.98E-28 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 Pfam PF02785 Biotin carboxylase C-terminal domain 329 441 3.3E-26 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 SMART SM00878 329 443 1.4E-38 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 597 614 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 SUPERFAMILY SSF52440 2 114 6.04E-43 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_28390 67325a119bd7f9069b67e48511f843dd 645 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 138 317 4.7E-58 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 281 288 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_28390 67325a119bd7f9069b67e48511f843dd 645 Gene3D G3DSA:3.30.470.130 1 447 4.3E-168 T 12-10-2018 AFR_06995 fa3d6fc51c28b7bfd2d6df302b26a5c4 352 Pfam PF10282 Lactonase, 7-bladed beta-propeller 8 342 1.0E-84 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller AFR_06995 fa3d6fc51c28b7bfd2d6df302b26a5c4 352 SUPERFAMILY SSF51004 17 327 1.6E-30 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily AFR_06995 fa3d6fc51c28b7bfd2d6df302b26a5c4 352 Gene3D G3DSA:2.130.10.10 2 344 1.0E-97 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_23095 9660b99a37051ca885c3234a742d330a 701 Pfam PF03176 MMPL family 30 345 8.1E-43 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_23095 9660b99a37051ca885c3234a742d330a 701 Pfam PF03176 MMPL family 441 669 2.5E-32 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_23095 9660b99a37051ca885c3234a742d330a 701 SUPERFAMILY SSF82866 446 665 3.01E-24 T 12-10-2018 AFR_23095 9660b99a37051ca885c3234a742d330a 701 SUPERFAMILY SSF82866 100 319 1.83E-22 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 SUPERFAMILY SSF51905 3 333 5.06E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 324 2.8E-59 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 Gene3D G3DSA:3.50.50.100 1 393 8.6E-105 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.0E-6 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 1.0E-6 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 1.0E-6 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.7E-13 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 2.7E-13 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 2.7E-13 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.7E-13 T 12-10-2018 AFR_02995 4cd16875851c04081d27bd6ab0e60e3d 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.7E-13 T 12-10-2018 AFR_23630 becde28c8e0b6643acdd13e1aa57409a 277 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_23630 becde28c8e0b6643acdd13e1aa57409a 277 SMART SM00382 31 219 9.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_23630 becde28c8e0b6643acdd13e1aa57409a 277 Gene3D G3DSA:3.40.50.300 6 259 1.2E-65 T 12-10-2018 AFR_23630 becde28c8e0b6643acdd13e1aa57409a 277 Pfam PF00005 ABC transporter 24 170 1.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_23630 becde28c8e0b6643acdd13e1aa57409a 277 SUPERFAMILY SSF52540 5 232 4.15E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.0E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 Pfam PF03466 LysR substrate binding domain 92 288 1.1E-26 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 Gene3D G3DSA:3.40.190.10 96 165 1.3E-24 T 12-10-2018 AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 Gene3D G3DSA:3.40.190.10 166 259 1.3E-24 T 12-10-2018 AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 Gene3D G3DSA:1.10.10.10 1 87 6.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 SUPERFAMILY SSF46785 4 88 1.63E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 SUPERFAMILY SSF53850 91 291 1.0E-25 T 12-10-2018 AFR_01070 b6c40b2098e097c5d22c1f45a85d3144 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 7.7E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 Pfam PF08544 GHMP kinases C terminal 224 298 4.9E-9 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 SUPERFAMILY SSF54211 19 174 4.86E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 Gene3D G3DSA:3.30.230.10 8 176 2.7E-57 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 Pfam PF00288 GHMP kinases N terminal domain 103 161 5.7E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 19 305 30.157 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 PIRSF PIRSF010376 18 314 1.6E-77 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 Gene3D G3DSA:3.30.70.890 179 315 1.2E-42 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 20 294 7.7E-52 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFR_39790 ed1b9345b30f04595fd769cd5b96de9d 315 SUPERFAMILY SSF55060 181 302 1.73E-24 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFR_17955 ed916057b59c0b446642b7b703b20c3a 685 Gene3D G3DSA:3.40.50.2000 13 371 6.2E-46 T 12-10-2018 AFR_17955 ed916057b59c0b446642b7b703b20c3a 685 Gene3D G3DSA:3.40.50.2000 189 360 6.2E-46 T 12-10-2018 AFR_17955 ed916057b59c0b446642b7b703b20c3a 685 Pfam PF00534 Glycosyl transferases group 1 194 353 4.5E-32 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_17955 ed916057b59c0b446642b7b703b20c3a 685 SUPERFAMILY SSF53756 2 375 5.23E-59 T 12-10-2018 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 ProSitePatterns PS00786 5'-nucleotidase signature 2. 132 143 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 Gene3D G3DSA:3.60.21.10 32 364 5.5E-100 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_08555 f5312f4c0146d3adb92251799a42855f 589 SUPERFAMILY SSF55816 362 572 2.62E-38 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 SUPERFAMILY SSF56300 32 364 2.17E-80 T 12-10-2018 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 Gene3D G3DSA:3.90.780.10 365 574 3.2E-54 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 PRINTS PR01607 Apyrase family signature 300 320 2.5E-21 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 PRINTS PR01607 Apyrase family signature 36 54 2.5E-21 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 PRINTS PR01607 Apyrase family signature 428 451 2.5E-21 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 PRINTS PR01607 Apyrase family signature 235 252 2.5E-21 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 PRINTS PR01607 Apyrase family signature 267 290 2.5E-21 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 PRINTS PR01607 Apyrase family signature 518 537 2.5E-21 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 Pfam PF02872 5'-nucleotidase, C-terminal domain 365 541 3.5E-27 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_08555 f5312f4c0146d3adb92251799a42855f 589 Pfam PF00149 Calcineurin-like phosphoesterase 38 284 5.0E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 Pfam PF00753 Metallo-beta-lactamase superfamily 29 174 6.0E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 559 3.1E-145 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 SUPERFAMILY SSF56281 19 434 4.07E-93 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 SMART SM00849 31 225 6.2E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 417 5.2E-10 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 PIRSF PIRSF004803 14 562 3.7E-199 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 Gene3D G3DSA:3.40.50.10710 217 375 1.0E-172 T 12-10-2018 AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 374 402 - T 12-10-2018 IPR001587 Ribonuclease J, conserved site AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 Hamap MF_01491 Ribonuclease J [rnj]. 14 562 40.666 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 Gene3D G3DSA:3.60.15.10 20 446 1.0E-172 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_35840 930ca5b99f1cfa4c50263361db25e79f 562 Gene3D G3DSA:3.10.20.580 459 562 4.8E-16 T 12-10-2018 AFR_15680 bfc22471049276c216e6b5db5e064ca1 363 SUPERFAMILY SSF52540 13 253 6.28E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15680 bfc22471049276c216e6b5db5e064ca1 363 Pfam PF08402 TOBE domain 282 360 5.6E-10 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFR_15680 bfc22471049276c216e6b5db5e064ca1 363 Pfam PF00005 ABC transporter 31 172 4.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_15680 bfc22471049276c216e6b5db5e064ca1 363 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_15680 bfc22471049276c216e6b5db5e064ca1 363 SUPERFAMILY SSF50331 247 360 6.23E-9 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_15680 bfc22471049276c216e6b5db5e064ca1 363 Gene3D G3DSA:3.40.50.300 12 289 1.3E-77 T 12-10-2018 AFR_15680 bfc22471049276c216e6b5db5e064ca1 363 SMART SM00382 39 222 3.7E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_23760 0589b5fdac922c2630a7dddee79418d0 250 Gene3D G3DSA:3.30.450.40 71 238 7.7E-49 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_23760 0589b5fdac922c2630a7dddee79418d0 250 SMART SM00346 1 89 8.7E-17 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_23760 0589b5fdac922c2630a7dddee79418d0 250 Pfam PF09339 IclR helix-turn-helix domain 4 52 3.3E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_23760 0589b5fdac922c2630a7dddee79418d0 250 Pfam PF01614 Bacterial transcriptional regulator 118 233 3.6E-27 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_23760 0589b5fdac922c2630a7dddee79418d0 250 SUPERFAMILY SSF55781 64 237 6.02E-42 T 12-10-2018 AFR_23760 0589b5fdac922c2630a7dddee79418d0 250 SUPERFAMILY SSF46785 3 70 1.73E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23760 0589b5fdac922c2630a7dddee79418d0 250 Gene3D G3DSA:1.10.10.10 1 68 2.4E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34015 c1f8b762b2c0f1ffdc99a308c13b7f1f 173 Gene3D G3DSA:3.90.1010.20 114 173 4.7E-5 T 12-10-2018 AFR_34015 c1f8b762b2c0f1ffdc99a308c13b7f1f 173 SMART SM00900 90 171 2.6E-6 T 12-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 AFR_34015 c1f8b762b2c0f1ffdc99a308c13b7f1f 173 Pfam PF04205 FMN-binding domain 98 168 2.4E-7 T 12-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 AFR_00360 d4d1f372b0b61857eb8fd42494adb5f1 392 SMART SM00530 4 60 2.4E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_00360 d4d1f372b0b61857eb8fd42494adb5f1 392 Gene3D G3DSA:1.25.40.10 120 390 2.3E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00360 d4d1f372b0b61857eb8fd42494adb5f1 392 Pfam PF13560 Helix-turn-helix domain 2 59 1.4E-8 T 12-10-2018 AFR_00360 d4d1f372b0b61857eb8fd42494adb5f1 392 SUPERFAMILY SSF47413 2 62 4.15E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_00360 d4d1f372b0b61857eb8fd42494adb5f1 392 Gene3D G3DSA:1.10.260.40 1 78 1.2E-10 T 12-10-2018 AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 SMART SM00091 314 380 8.6E-10 T 12-10-2018 IPR000014 PAS domain AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 Pfam PF00989 PAS fold 315 425 1.5E-9 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 SUPERFAMILY SSF55785 305 426 3.21E-19 T 12-10-2018 IPR035965 PAS domain superfamily AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 436 588 1.7E-32 T 12-10-2018 IPR000160 GGDEF domain AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 Gene3D G3DSA:3.20.20.450 607 850 1.0E-82 T 12-10-2018 IPR035919 EAL domain superfamily AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 Pfam PF00563 EAL domain 609 837 4.7E-64 T 12-10-2018 IPR001633 EAL domain AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 Gene3D G3DSA:3.30.450.20 301 426 4.7E-18 T 12-10-2018 AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 SUPERFAMILY SSF55073 444 592 4.08E-43 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 Pfam PF00990 Diguanylate cyclase, GGDEF domain 439 586 4.4E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 SUPERFAMILY SSF141868 609 847 1.31E-72 T 12-10-2018 IPR035919 EAL domain superfamily AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 SMART SM00267 428 592 4.1E-58 T 12-10-2018 IPR000160 GGDEF domain AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 SMART SM00052 602 842 2.3E-92 T 12-10-2018 IPR001633 EAL domain AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 314 435 7.3E-16 T 12-10-2018 IPR000014 PAS domain AFR_25770 3a1f4e9a7b8f6d29ce49f7ed061297c2 851 Gene3D G3DSA:3.30.70.270 433 606 4.6E-51 T 12-10-2018 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 Gene3D G3DSA:1.25.40.10 220 358 7.9E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 Gene3D G3DSA:1.25.40.10 58 212 7.1E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 SMART SM00028 98 131 0.53 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 SMART SM00028 256 289 77.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 SMART SM00028 138 171 200.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 SUPERFAMILY SSF48452 98 285 1.98E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 SUPERFAMILY SSF55073 366 524 4.39E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 359 525 2.3E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 Gene3D G3DSA:3.30.70.270 359 527 5.1E-51 T 12-10-2018 AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 SMART SM00267 350 526 1.4E-53 T 12-10-2018 IPR000160 GGDEF domain AFR_13940 bbf8e0afb024dd62f7ea9e31b1a46fd4 530 Pfam PF00990 Diguanylate cyclase, GGDEF domain 361 522 2.7E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_40390 ad5c1d2000c9b93006168492aa366e7a 460 SUPERFAMILY SSF64518 98 453 5.1E-16 T 12-10-2018 AFR_40390 ad5c1d2000c9b93006168492aa366e7a 460 PRINTS PR01005 Flagellar hook-associated protein signature 165 189 1.4E-6 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFR_40390 ad5c1d2000c9b93006168492aa366e7a 460 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 1.4E-6 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFR_40390 ad5c1d2000c9b93006168492aa366e7a 460 PRINTS PR01005 Flagellar hook-associated protein signature 132 152 1.4E-6 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFR_40390 ad5c1d2000c9b93006168492aa366e7a 460 Pfam PF00460 Flagella basal body rod protein 8 38 7.3E-7 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFR_40390 ad5c1d2000c9b93006168492aa366e7a 460 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 453 3.0E-96 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFR_40390 ad5c1d2000c9b93006168492aa366e7a 460 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 403 453 1.9E-14 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFR_17325 354ba9e77321ef662111a42fc331c5da 345 Gene3D G3DSA:1.10.101.10 109 178 1.1E-12 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_17325 354ba9e77321ef662111a42fc331c5da 345 Pfam PF01471 Putative peptidoglycan binding domain 121 171 7.4E-13 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_17325 354ba9e77321ef662111a42fc331c5da 345 Gene3D G3DSA:2.40.420.20 269 343 3.0E-9 T 12-10-2018 AFR_17325 354ba9e77321ef662111a42fc331c5da 345 SUPERFAMILY SSF47090 108 172 2.04E-13 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_05645 372826c2bb6a1be0eb8b4859601deac0 334 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 5 235 1.1E-72 T 12-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AFR_05645 372826c2bb6a1be0eb8b4859601deac0 334 Gene3D G3DSA:3.30.1330.100 9 222 8.0E-69 T 12-10-2018 AFR_05645 372826c2bb6a1be0eb8b4859601deac0 334 SUPERFAMILY SSF144010 7 241 4.84E-65 T 12-10-2018 AFR_05645 372826c2bb6a1be0eb8b4859601deac0 334 Pfam PF01996 F420-0:Gamma-glutamyl ligase 85 211 9.2E-33 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AFR_05645 372826c2bb6a1be0eb8b4859601deac0 334 Pfam PF01996 F420-0:Gamma-glutamyl ligase 14 56 6.3E-8 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AFR_05645 372826c2bb6a1be0eb8b4859601deac0 334 Gene3D G3DSA:3.90.1660.10 53 235 8.0E-69 T 12-10-2018 AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 SMART SM00052 493 734 1.1E-112 T 12-10-2018 IPR001633 EAL domain AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 327 481 1.6E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 Pfam PF00563 EAL domain 500 729 6.4E-75 T 12-10-2018 IPR001633 EAL domain AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 Gene3D G3DSA:3.30.70.270 327 496 6.4E-52 T 12-10-2018 AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 SUPERFAMILY SSF55073 331 485 4.87E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 Pfam PF00990 Diguanylate cyclase, GGDEF domain 328 477 4.5E-41 T 12-10-2018 IPR000160 GGDEF domain AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 Gene3D G3DSA:3.20.20.450 497 745 5.7E-95 T 12-10-2018 IPR035919 EAL domain superfamily AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 SMART SM00267 316 483 4.5E-55 T 12-10-2018 IPR000160 GGDEF domain AFR_20105 f8928358ef83d3cdcff6613dceaf2990 746 SUPERFAMILY SSF141868 499 739 1.06E-86 T 12-10-2018 IPR035919 EAL domain superfamily AFR_28365 465ff9b308bb80b3ff24387a10ef7b3a 416 PRINTS PR00463 E-class P450 group I signature 302 326 1.9E-6 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28365 465ff9b308bb80b3ff24387a10ef7b3a 416 PRINTS PR00463 E-class P450 group I signature 262 280 1.9E-6 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28365 465ff9b308bb80b3ff24387a10ef7b3a 416 SUPERFAMILY SSF48264 8 366 4.71E-58 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28365 465ff9b308bb80b3ff24387a10ef7b3a 416 Gene3D G3DSA:1.10.630.10 2 399 3.3E-146 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_28365 465ff9b308bb80b3ff24387a10ef7b3a 416 Pfam PF00067 Cytochrome P450 260 356 8.6E-15 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_05805 deda9197f049bbca6ff343fa9d09ef5d 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 50 2.2E-10 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_05805 deda9197f049bbca6ff343fa9d09ef5d 70 Pfam PF12728 Helix-turn-helix domain 4 51 3.4E-13 T 12-10-2018 AFR_05805 deda9197f049bbca6ff343fa9d09ef5d 70 Gene3D G3DSA:1.10.1660.10 2 51 1.1E-8 T 12-10-2018 AFR_05805 deda9197f049bbca6ff343fa9d09ef5d 70 SUPERFAMILY SSF46955 4 51 2.56E-5 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_00175 a617121f312033a63663a9cd57d3f17f 293 Pfam PF00682 HMGL-like 5 270 4.2E-47 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFR_00175 a617121f312033a63663a9cd57d3f17f 293 SUPERFAMILY SSF51569 1 287 5.01E-70 T 12-10-2018 AFR_00175 a617121f312033a63663a9cd57d3f17f 293 Gene3D G3DSA:3.20.20.70 1 289 2.9E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_18565 d96378f454f3692c4ed7d47275a51acc 756 Pfam PF03176 MMPL family 400 712 1.9E-35 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_18565 d96378f454f3692c4ed7d47275a51acc 756 Pfam PF03176 MMPL family 65 369 1.6E-47 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_18565 d96378f454f3692c4ed7d47275a51acc 756 SUPERFAMILY SSF82866 492 704 1.57E-27 T 12-10-2018 AFR_18565 d96378f454f3692c4ed7d47275a51acc 756 Gene3D G3DSA:1.20.1640.10 505 701 5.5E-6 T 12-10-2018 AFR_18565 d96378f454f3692c4ed7d47275a51acc 756 SUPERFAMILY SSF82866 115 336 1.57E-30 T 12-10-2018 AFR_18565 d96378f454f3692c4ed7d47275a51acc 756 Gene3D G3DSA:1.20.1640.10 155 339 8.8E-7 T 12-10-2018 AFR_31250 083e3b7da7b5c8bec0de94eec5f4415f 93 Pfam PF14542 GCN5-related N-acetyl-transferase 13 90 1.9E-24 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase AFR_31250 083e3b7da7b5c8bec0de94eec5f4415f 93 SUPERFAMILY SSF55729 3 92 1.68E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_31250 083e3b7da7b5c8bec0de94eec5f4415f 93 Gene3D G3DSA:3.40.630.30 3 93 2.6E-26 T 12-10-2018 AFR_30675 f9a5bab8b447209c49ce50eec6a56ab0 233 Gene3D G3DSA:3.40.50.1820 1 232 9.0E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_30675 f9a5bab8b447209c49ce50eec6a56ab0 233 Pfam PF12697 Alpha/beta hydrolase family 5 227 4.0E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_30675 f9a5bab8b447209c49ce50eec6a56ab0 233 SUPERFAMILY SSF53474 5 230 5.71E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 12-10-2018 IPR018120 Glycoside hydrolase family 1, active site AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 SUPERFAMILY SSF51445 15 462 3.77E-156 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 TIGRFAM TIGR03356 BGL: beta-galactosidase 19 457 2.3E-182 T 12-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 22 36 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 Gene3D G3DSA:3.20.20.80 13 466 3.0E-170 T 12-10-2018 AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 Pfam PF00232 Glycosyl hydrolase family 1 17 462 3.8E-160 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 300 314 1.8E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 1.8E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 1.8E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 1.8E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_31960 eba7e587748b5c1ca6cb695b8e452815 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 1.8E-18 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_29250 53ccd4eeb564fba4a76612a48c17b971 290 SUPERFAMILY SSF53474 35 284 2.06E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29250 53ccd4eeb564fba4a76612a48c17b971 290 Gene3D G3DSA:3.40.50.1820 30 290 1.2E-81 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29250 53ccd4eeb564fba4a76612a48c17b971 290 Pfam PF01738 Dienelactone hydrolase family 130 213 1.9E-4 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFR_18220 3990fd47f419b246289a33fb2eb54c3d 260 Gene3D G3DSA:1.10.3720.10 1 252 3.9E-45 T 12-10-2018 IPR035906 MetI-like superfamily AFR_18220 3990fd47f419b246289a33fb2eb54c3d 260 SUPERFAMILY SSF161098 4 252 3.18E-50 T 12-10-2018 IPR035906 MetI-like superfamily AFR_18220 3990fd47f419b246289a33fb2eb54c3d 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 248 6.9E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_39250 185a1ce4921e76ab1880d2eec60bd85e 470 Gene3D G3DSA:3.40.50.1010 42 185 1.2E-18 T 12-10-2018 AFR_39250 185a1ce4921e76ab1880d2eec60bd85e 470 SUPERFAMILY SSF52540 259 421 2.97E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39250 185a1ce4921e76ab1880d2eec60bd85e 470 Pfam PF02562 PhoH-like protein 261 464 7.3E-54 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 AFR_39250 185a1ce4921e76ab1880d2eec60bd85e 470 Gene3D G3DSA:3.40.50.300 259 466 6.8E-53 T 12-10-2018 AFR_39250 185a1ce4921e76ab1880d2eec60bd85e 470 SMART SM00670 44 171 2.5E-14 T 12-10-2018 IPR002716 PIN domain AFR_39250 185a1ce4921e76ab1880d2eec60bd85e 470 Pfam PF13638 PIN domain 46 184 5.4E-27 T 12-10-2018 IPR002716 PIN domain AFR_39250 185a1ce4921e76ab1880d2eec60bd85e 470 SUPERFAMILY SSF88723 46 180 4.22E-8 T 12-10-2018 IPR029060 PIN-like domain superfamily AFR_32780 94714adda9d9e34571175a39668eb11f 353 SUPERFAMILY SSF51679 1 348 2.62E-87 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_32780 94714adda9d9e34571175a39668eb11f 353 Pfam PF00296 Luciferase-like monooxygenase 1 324 1.1E-84 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_32780 94714adda9d9e34571175a39668eb11f 353 Gene3D G3DSA:3.20.20.30 1 352 3.6E-127 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_40700 694a0bb652c96d6cd043112306baa748 198 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 32 197 31.403 T 12-10-2018 IPR022939 Uncharacterised protein family UPF0678 AFR_40700 694a0bb652c96d6cd043112306baa748 198 Pfam PF08768 Domain of unknown function (DUF1794) 40 195 9.3E-45 T 12-10-2018 IPR014878 Domain of unknown function DUF1794 AFR_40700 694a0bb652c96d6cd043112306baa748 198 Gene3D G3DSA:2.40.128.20 12 198 3.2E-62 T 12-10-2018 IPR012674 Calycin AFR_40700 694a0bb652c96d6cd043112306baa748 198 SUPERFAMILY SSF50814 34 195 4.06E-40 T 12-10-2018 IPR012674 Calycin AFR_01530 a2c6d8d0d484561db1200ff15658e366 256 SUPERFAMILY SSF54593 137 251 1.55E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_01530 a2c6d8d0d484561db1200ff15658e366 256 SUPERFAMILY SSF54593 5 120 2.01E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_01530 a2c6d8d0d484561db1200ff15658e366 256 Gene3D G3DSA:3.10.180.10 130 255 1.6E-38 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_01530 a2c6d8d0d484561db1200ff15658e366 256 Gene3D G3DSA:3.10.180.10 4 123 2.8E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_03930 2cab6b57337138845eb4b1b53ee7a189 353 PIRSF PIRSF001361 2 353 6.8E-148 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFR_03930 2cab6b57337138845eb4b1b53ee7a189 353 Pfam PF00793 DAHP synthetase I family 48 337 5.1E-93 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFR_03930 2cab6b57337138845eb4b1b53ee7a189 353 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 11 350 6.7E-144 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFR_03930 2cab6b57337138845eb4b1b53ee7a189 353 Gene3D G3DSA:3.20.20.70 6 352 6.5E-147 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_03930 2cab6b57337138845eb4b1b53ee7a189 353 SUPERFAMILY SSF51569 12 344 1.36E-124 T 12-10-2018 AFR_22345 fae8a286d619dfd292caaa2b3391f113 343 Pfam PF00296 Luciferase-like monooxygenase 1 296 2.7E-67 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_22345 fae8a286d619dfd292caaa2b3391f113 343 SUPERFAMILY SSF51679 1 325 2.09E-72 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22345 fae8a286d619dfd292caaa2b3391f113 343 Gene3D G3DSA:3.20.20.30 3 337 1.7E-78 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_29760 9c3b83f6110bd2bfe8e3bf7315e6ccb6 287 Gene3D G3DSA:3.90.25.10 133 263 4.4E-68 T 12-10-2018 AFR_29760 9c3b83f6110bd2bfe8e3bf7315e6ccb6 287 Pfam PF05368 NmrA-like family 1 217 2.0E-25 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 AFR_29760 9c3b83f6110bd2bfe8e3bf7315e6ccb6 287 Gene3D G3DSA:3.40.50.720 2 261 4.4E-68 T 12-10-2018 AFR_29760 9c3b83f6110bd2bfe8e3bf7315e6ccb6 287 SUPERFAMILY SSF51735 1 277 2.53E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_33285 997775760806903adc26ac4258c6e32f 132 SUPERFAMILY SSF46955 4 52 1.14E-10 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_33285 997775760806903adc26ac4258c6e32f 132 Gene3D G3DSA:2.40.50.100 63 127 5.1E-18 T 12-10-2018 AFR_33285 997775760806903adc26ac4258c6e32f 132 Gene3D G3DSA:1.10.1660.10 5 55 5.0E-10 T 12-10-2018 AFR_33285 997775760806903adc26ac4258c6e32f 132 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 3 34 4.1E-9 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_33285 997775760806903adc26ac4258c6e32f 132 Pfam PF03459 TOBE domain 64 124 3.2E-12 T 12-10-2018 IPR005116 Transport-associated OB, type 1 AFR_33285 997775760806903adc26ac4258c6e32f 132 SUPERFAMILY SSF50331 63 129 1.24E-16 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_33285 997775760806903adc26ac4258c6e32f 132 Pfam PF00376 MerR family regulatory protein 5 39 8.6E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 ProSitePatterns PS00893 Nudix box signature. 160 181 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 SUPERFAMILY SSF46785 7 70 2.59E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 SUPERFAMILY SSF55811 97 259 5.42E-31 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.8E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.8E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 Pfam PF00293 NUDIX domain 128 239 2.5E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 Gene3D G3DSA:3.90.79.10 83 259 2.7E-36 T 12-10-2018 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 4.8E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 Gene3D G3DSA:1.10.10.10 2 72 1.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06595 e2df5eb6b5358b17c6353158368502c8 265 SMART SM00345 8 67 7.5E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 120 1.9E-28 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 349 3.0E-116 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 348 32.996 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 SUPERFAMILY SSF55347 131 335 4.76E-63 T 12-10-2018 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 Gene3D G3DSA:3.40.50.720 9 345 7.1E-126 T 12-10-2018 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 245 259 - T 12-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 Gene3D G3DSA:3.30.360.10 130 331 7.1E-126 T 12-10-2018 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 SUPERFAMILY SSF51735 8 159 2.26E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 334 2.1E-41 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 PIRSF PIRSF000148 5 352 5.4E-111 T 12-10-2018 AFR_41740 f9f5dbdfcf87d819afe319c5499f5f01 356 SMART SM00859 7 122 8.5E-36 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 SUPERFAMILY SSF46785 249 314 5.73E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 SMART SM00419 264 314 0.0024 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 Pfam PF12840 Helix-turn-helix domain 252 308 5.7E-11 T 12-10-2018 AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 SMART SM00418 251 323 4.6E-4 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 253 268 5.0E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 299 314 5.0E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 284 299 5.0E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20840 86e0d4ce7bb46fe7f9a36d077f414e72 325 Gene3D G3DSA:1.10.10.10 242 322 2.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07985 aa9fa29c2e699de3e0fbec5e0dd92ecd 418 SUPERFAMILY SSF103473 12 406 1.44E-38 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_07985 aa9fa29c2e699de3e0fbec5e0dd92ecd 418 Gene3D G3DSA:1.20.1250.20 7 404 7.4E-33 T 12-10-2018 AFR_07985 aa9fa29c2e699de3e0fbec5e0dd92ecd 418 Pfam PF07690 Major Facilitator Superfamily 259 410 1.5E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_21305 74edcd6e9485c24a0c84ed0cfda89ddc 323 Gene3D G3DSA:1.10.150.130 23 109 1.3E-17 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_21305 74edcd6e9485c24a0c84ed0cfda89ddc 323 Pfam PF00589 Phage integrase family 126 300 4.3E-31 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_21305 74edcd6e9485c24a0c84ed0cfda89ddc 323 SUPERFAMILY SSF56349 20 307 2.59E-47 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_21305 74edcd6e9485c24a0c84ed0cfda89ddc 323 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 29 98 1.1E-11 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFR_21305 74edcd6e9485c24a0c84ed0cfda89ddc 323 Gene3D G3DSA:1.10.443.10 125 306 8.8E-43 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 Gene3D G3DSA:2.60.120.260 23 154 5.7E-25 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 SUPERFAMILY SSF55797 247 371 1.22E-24 T 12-10-2018 IPR035940 CAP superfamily AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 PRINTS PR01217 Proline rich extensin signature 151 172 4.0E-12 T 12-10-2018 AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 PRINTS PR01217 Proline rich extensin signature 185 201 4.0E-12 T 12-10-2018 AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 PRINTS PR01217 Proline rich extensin signature 221 246 4.0E-12 T 12-10-2018 AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 PRINTS PR01217 Proline rich extensin signature 202 219 4.0E-12 T 12-10-2018 AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 Pfam PF00188 Cysteine-rich secretory protein family 255 370 1.3E-22 T 12-10-2018 IPR014044 CAP domain AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 Gene3D G3DSA:3.40.33.10 189 371 3.5E-58 T 12-10-2018 IPR035940 CAP superfamily AFR_07515 d64b7408e90bc69d38b6b24cb0bc4298 374 SUPERFAMILY SSF49785 32 153 1.7E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_00655 8f0965ded2bb185ad689576c95c44a6e 329 SUPERFAMILY SSF101478 3 324 1.29E-52 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFR_00655 8f0965ded2bb185ad689576c95c44a6e 329 Gene3D G3DSA:1.10.4080.10 1 328 1.7E-57 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFR_00655 8f0965ded2bb185ad689576c95c44a6e 329 Pfam PF03747 ADP-ribosylglycohydrolase 6 309 6.4E-52 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 AFR_28170 bc8128656bb1cd9189f345df7e12501e 381 SUPERFAMILY SSF52540 4 122 2.08E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05920 fa4f20ad11bdaebd2e381e6f93851388 326 Pfam PF07859 alpha/beta hydrolase fold 93 299 8.0E-52 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_05920 fa4f20ad11bdaebd2e381e6f93851388 326 Gene3D G3DSA:3.40.50.1820 8 325 1.8E-86 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_05920 fa4f20ad11bdaebd2e381e6f93851388 326 SUPERFAMILY SSF53474 59 324 9.12E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_25660 c72938d823ba959910b72ec3abb1bb47 244 Pfam PF00005 ABC transporter 27 172 8.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_25660 c72938d823ba959910b72ec3abb1bb47 244 SMART SM00382 35 221 7.4E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25660 c72938d823ba959910b72ec3abb1bb47 244 Gene3D G3DSA:3.40.50.300 5 236 3.4E-69 T 12-10-2018 AFR_25660 c72938d823ba959910b72ec3abb1bb47 244 SUPERFAMILY SSF52540 8 225 1.18E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21395 1dcc0a11f75ba51db66971c9e052a157 258 Pfam PF07398 MDMPI C-terminal domain 152 249 1.6E-15 T 12-10-2018 IPR010872 MDMPI C-terminal AFR_21395 1dcc0a11f75ba51db66971c9e052a157 258 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 16 209 3.4E-23 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_21395 1dcc0a11f75ba51db66971c9e052a157 258 Gene3D G3DSA:1.20.120.450 2 143 7.3E-10 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_21395 1dcc0a11f75ba51db66971c9e052a157 258 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 139 4.7E-21 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_21395 1dcc0a11f75ba51db66971c9e052a157 258 SUPERFAMILY SSF109854 6 145 5.04E-10 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 Gene3D G3DSA:3.40.50.1820 6 381 3.7E-135 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 SUPERFAMILY SSF53474 5 377 5.24E-99 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 PIRSF PIRSF001112 1 381 7.4E-135 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 PRINTS PR00412 Epoxide hydrolase signature 353 375 1.3E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 PRINTS PR00412 Epoxide hydrolase signature 321 337 1.3E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 PRINTS PR00412 Epoxide hydrolase signature 102 120 1.3E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 PRINTS PR00412 Epoxide hydrolase signature 176 189 1.3E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 PRINTS PR00412 Epoxide hydrolase signature 131 146 1.3E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12005 9ccfd56dd9da3c2dee795c06aacb576b 381 Pfam PF06441 Epoxide hydrolase N terminus 6 111 2.4E-37 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_31630 dbf8f2ba99b8e078fe288695b1ae8d01 370 SUPERFAMILY SSF48264 26 342 5.65E-23 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_31630 dbf8f2ba99b8e078fe288695b1ae8d01 370 PRINTS PR00359 B-class P450 signature 315 324 6.8E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_31630 dbf8f2ba99b8e078fe288695b1ae8d01 370 PRINTS PR00359 B-class P450 signature 235 246 6.8E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_31630 dbf8f2ba99b8e078fe288695b1ae8d01 370 PRINTS PR00359 B-class P450 signature 324 335 6.8E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_31630 dbf8f2ba99b8e078fe288695b1ae8d01 370 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 317 326 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_31630 dbf8f2ba99b8e078fe288695b1ae8d01 370 Gene3D G3DSA:1.10.630.10 11 192 3.1E-10 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_31630 dbf8f2ba99b8e078fe288695b1ae8d01 370 Gene3D G3DSA:1.10.630.10 200 369 2.2E-11 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_16650 7c5b77730ea5e14ea37c27b1ec841db8 332 Pfam PF01497 Periplasmic binding protein 63 306 6.1E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFR_16650 7c5b77730ea5e14ea37c27b1ec841db8 332 SUPERFAMILY SSF53807 58 330 7.85E-48 T 12-10-2018 AFR_16650 7c5b77730ea5e14ea37c27b1ec841db8 332 Gene3D G3DSA:3.40.50.1980 40 148 1.6E-19 T 12-10-2018 AFR_16650 7c5b77730ea5e14ea37c27b1ec841db8 332 Gene3D G3DSA:3.40.50.1980 150 332 4.8E-39 T 12-10-2018 AFR_19155 debbad51d4fe0db3c17258d3c5c8ea88 421 Gene3D G3DSA:2.70.98.20 37 410 3.8E-65 T 12-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 AFR_19155 debbad51d4fe0db3c17258d3c5c8ea88 421 Pfam PF01179 Copper amine oxidase, enzyme domain 52 407 1.2E-40 T 12-10-2018 IPR015798 Copper amine oxidase, catalytic domain GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 AFR_19155 debbad51d4fe0db3c17258d3c5c8ea88 421 SUPERFAMILY SSF49998 40 407 6.93E-60 T 12-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 AFR_10835 8f350e71bf5f85d7448a318687cd29d9 166 Gene3D G3DSA:2.170.270.10 9 148 1.0E-21 T 12-10-2018 AFR_10835 8f350e71bf5f85d7448a318687cd29d9 166 SMART SM00317 13 125 1.5E-5 T 12-10-2018 IPR001214 SET domain GO:0005515 AFR_10835 8f350e71bf5f85d7448a318687cd29d9 166 Pfam PF00856 SET domain 86 119 3.2E-5 T 12-10-2018 IPR001214 SET domain GO:0005515 AFR_10835 8f350e71bf5f85d7448a318687cd29d9 166 SUPERFAMILY SSF82199 11 140 8.11E-23 T 12-10-2018 AFR_03215 6496b893090c82270e48dd1020b6bd74 347 Gene3D G3DSA:3.40.50.2300 139 286 1.8E-65 T 12-10-2018 AFR_03215 6496b893090c82270e48dd1020b6bd74 347 SUPERFAMILY SSF53822 36 328 3.44E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_03215 6496b893090c82270e48dd1020b6bd74 347 Pfam PF13407 Periplasmic binding protein domain 36 304 1.4E-45 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_03215 6496b893090c82270e48dd1020b6bd74 347 Gene3D G3DSA:3.40.50.2300 37 305 1.8E-65 T 12-10-2018 AFR_25760 24488f138934eae35df23c830cec5ecd 193 Gene3D G3DSA:1.20.1260.10 35 193 4.5E-23 T 12-10-2018 IPR012347 Ferritin-like AFR_25760 24488f138934eae35df23c830cec5ecd 193 Pfam PF03713 Domain of unknown function (DUF305) 46 190 6.7E-21 T 12-10-2018 IPR005183 Domain of unknown function DUF305 AFR_16945 f1560214f1350fc781e21d96e0668bce 297 Pfam PF13377 Periplasmic binding protein-like domain 142 295 2.1E-31 T 12-10-2018 AFR_16945 f1560214f1350fc781e21d96e0668bce 297 Gene3D G3DSA:3.40.50.2300 132 258 5.2E-52 T 12-10-2018 AFR_16945 f1560214f1350fc781e21d96e0668bce 297 Gene3D G3DSA:1.10.260.40 1 27 2.0E-7 T 12-10-2018 AFR_16945 f1560214f1350fc781e21d96e0668bce 297 Gene3D G3DSA:3.40.50.2300 28 275 5.2E-52 T 12-10-2018 AFR_16945 f1560214f1350fc781e21d96e0668bce 297 SUPERFAMILY SSF53822 48 296 6.52E-47 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_19865 6f88456ba6d11caab7f43fd5e360edde 379 SUPERFAMILY SSF53613 1 371 5.86E-37 T 12-10-2018 IPR029056 Ribokinase-like AFR_19865 6f88456ba6d11caab7f43fd5e360edde 379 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 328 341 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_19865 6f88456ba6d11caab7f43fd5e360edde 379 Gene3D G3DSA:3.40.1190.20 1 192 4.4E-33 T 12-10-2018 IPR029056 Ribokinase-like AFR_19865 6f88456ba6d11caab7f43fd5e360edde 379 Gene3D G3DSA:3.40.1190.20 279 378 4.0E-19 T 12-10-2018 IPR029056 Ribokinase-like AFR_19865 6f88456ba6d11caab7f43fd5e360edde 379 Pfam PF00294 pfkB family carbohydrate kinase 287 372 8.7E-15 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_19865 6f88456ba6d11caab7f43fd5e360edde 379 Pfam PF00294 pfkB family carbohydrate kinase 2 177 9.2E-16 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_30870 78769872f9cbc87c07bb13b4d3cde4fa 292 SUPERFAMILY SSF161098 56 280 4.45E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30870 78769872f9cbc87c07bb13b4d3cde4fa 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 281 5.1E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30870 78769872f9cbc87c07bb13b4d3cde4fa 292 Gene3D G3DSA:1.10.3720.10 50 290 1.4E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 Pfam PF03466 LysR substrate binding domain 88 281 3.9E-21 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 Gene3D G3DSA:1.10.10.10 3 90 2.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 Gene3D G3DSA:3.40.190.10 159 257 7.4E-22 T 12-10-2018 AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 SUPERFAMILY SSF46785 4 88 1.46E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 Gene3D G3DSA:3.40.190.10 91 274 7.4E-22 T 12-10-2018 AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.2E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_39260 5286bcc1c9e299797d6710e0634f32e1 291 SUPERFAMILY SSF53850 88 282 6.3E-21 T 12-10-2018 AFR_37020 fb36bb10e6709097086cd16e107c475e 391 SUPERFAMILY SSF53383 2 379 6.86E-96 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_37020 fb36bb10e6709097086cd16e107c475e 391 Gene3D G3DSA:3.40.640.10 13 260 3.5E-140 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_37020 fb36bb10e6709097086cd16e107c475e 391 Pfam PF00266 Aminotransferase class-V 3 370 1.1E-61 T 12-10-2018 IPR000192 Aminotransferase class V domain AFR_37020 fb36bb10e6709097086cd16e107c475e 391 Gene3D G3DSA:3.90.1150.10 3 372 3.5E-140 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_37020 fb36bb10e6709097086cd16e107c475e 391 PIRSF PIRSF005572 1 385 5.1E-116 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFR_31840 1ae371b77ec938c4ebb7384082e7e37c 442 Gene3D G3DSA:3.40.710.10 80 380 3.5E-76 T 12-10-2018 AFR_31840 1ae371b77ec938c4ebb7384082e7e37c 442 SUPERFAMILY SSF56601 104 350 5.63E-50 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_31840 1ae371b77ec938c4ebb7384082e7e37c 442 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 211 224 6.1E-9 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFR_31840 1ae371b77ec938c4ebb7384082e7e37c 442 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 132 143 6.1E-9 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFR_31840 1ae371b77ec938c4ebb7384082e7e37c 442 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 182 199 6.1E-9 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFR_31840 1ae371b77ec938c4ebb7384082e7e37c 442 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 100 331 1.5E-41 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFR_32105 8b6830ace1a373fd437fe01752730c16 880 Gene3D G3DSA:2.60.120.260 43 169 2.2E-38 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32105 8b6830ace1a373fd437fe01752730c16 880 Gene3D G3DSA:2.60.120.260 180 307 1.5E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32105 8b6830ace1a373fd437fe01752730c16 880 Pfam PF00754 F5/8 type C domain 191 303 2.2E-25 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32105 8b6830ace1a373fd437fe01752730c16 880 Pfam PF00754 F5/8 type C domain 52 164 3.4E-27 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32105 8b6830ace1a373fd437fe01752730c16 880 SUPERFAMILY SSF49785 47 169 6.17E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32105 8b6830ace1a373fd437fe01752730c16 880 SUPERFAMILY SSF49785 184 307 7.8E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15855 990cb27ea9316eaf9ca0652eb39d49cd 349 Gene3D G3DSA:3.40.190.150 51 341 1.5E-65 T 12-10-2018 AFR_15855 990cb27ea9316eaf9ca0652eb39d49cd 349 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 71 347 9.2E-28 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 AFR_15855 990cb27ea9316eaf9ca0652eb39d49cd 349 Gene3D G3DSA:3.40.190.10 149 276 1.5E-65 T 12-10-2018 AFR_15855 990cb27ea9316eaf9ca0652eb39d49cd 349 SUPERFAMILY SSF53850 52 321 3.46E-9 T 12-10-2018 AFR_15855 990cb27ea9316eaf9ca0652eb39d49cd 349 PIRSF PIRSF017082 15 349 2.8E-95 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 AFR_02200 5622be313db2dc37872b717ec7587950 368 SUPERFAMILY SSF48256 4 354 1.83E-97 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFR_02200 5622be313db2dc37872b717ec7587950 368 PRINTS PR00143 Citrate synthase signature 160 175 1.1E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_02200 5622be313db2dc37872b717ec7587950 368 PRINTS PR00143 Citrate synthase signature 314 328 1.1E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_02200 5622be313db2dc37872b717ec7587950 368 PRINTS PR00143 Citrate synthase signature 294 310 1.1E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_02200 5622be313db2dc37872b717ec7587950 368 PRINTS PR00143 Citrate synthase signature 182 210 1.1E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_02200 5622be313db2dc37872b717ec7587950 368 PRINTS PR00143 Citrate synthase signature 235 255 1.1E-28 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_02200 5622be313db2dc37872b717ec7587950 368 Gene3D G3DSA:1.10.580.10 22 334 2.5E-76 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_02200 5622be313db2dc37872b717ec7587950 368 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 4.7E-87 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_02200 5622be313db2dc37872b717ec7587950 368 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_02200 5622be313db2dc37872b717ec7587950 368 Gene3D G3DSA:1.10.230.10 208 308 2.5E-76 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFR_17940 df8da2dd04fe9fdfa126419ab27858ab 293 SUPERFAMILY SSF51679 3 292 1.57E-59 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_17940 df8da2dd04fe9fdfa126419ab27858ab 293 Gene3D G3DSA:3.20.20.30 2 293 2.1E-58 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_17940 df8da2dd04fe9fdfa126419ab27858ab 293 Pfam PF00296 Luciferase-like monooxygenase 5 235 1.0E-39 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_17940 df8da2dd04fe9fdfa126419ab27858ab 293 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 19 239 3.9E-82 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c AFR_37680 67c37a7fda9c15a33783bfdf67d5f26e 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 110 8.0E-44 T 12-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 AFR_37680 67c37a7fda9c15a33783bfdf67d5f26e 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 21.767 T 12-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 AFR_37680 67c37a7fda9c15a33783bfdf67d5f26e 111 SUPERFAMILY SSF103481 10 109 5.62E-10 T 12-10-2018 AFR_01280 ef1a9476693157ba4e152d24eaf6589b 999 Gene3D G3DSA:3.40.50.2000 10 363 3.2E-52 T 12-10-2018 AFR_01280 ef1a9476693157ba4e152d24eaf6589b 999 Gene3D G3DSA:3.40.50.2000 173 348 3.2E-52 T 12-10-2018 AFR_01280 ef1a9476693157ba4e152d24eaf6589b 999 Pfam PF13439 Glycosyltransferase Family 4 15 172 6.7E-10 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_01280 ef1a9476693157ba4e152d24eaf6589b 999 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 496 697 6.2E-5 T 12-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 AFR_01280 ef1a9476693157ba4e152d24eaf6589b 999 SUPERFAMILY SSF53756 9 363 8.64E-60 T 12-10-2018 AFR_01280 ef1a9476693157ba4e152d24eaf6589b 999 Pfam PF00534 Glycosyl transferases group 1 187 328 3.4E-30 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 Hamap MF_00235 Adenylate kinase [adk]. 1 187 35.932 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 PRINTS PR00094 Adenylate kinase signature 134 149 1.9E-26 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 PRINTS PR00094 Adenylate kinase signature 151 165 1.9E-26 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 PRINTS PR00094 Adenylate kinase signature 32 46 1.9E-26 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 PRINTS PR00094 Adenylate kinase signature 4 17 1.9E-26 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 PRINTS PR00094 Adenylate kinase signature 82 98 1.9E-26 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 Gene3D G3DSA:3.40.50.300 1 191 8.6E-59 T 12-10-2018 AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 SUPERFAMILY SSF52540 1 187 5.26E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16640 cdb3d04f66b57207303343b5a756ccd8 217 Pfam PF00406 Adenylate kinase 6 164 1.7E-41 T 12-10-2018 AFR_19925 23733db75c3b6976ece168744472c548 219 Pfam PF00072 Response regulator receiver domain 3 107 1.2E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19925 23733db75c3b6976ece168744472c548 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 5.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_19925 23733db75c3b6976ece168744472c548 219 Gene3D G3DSA:3.40.50.12740 1 210 6.9E-46 T 12-10-2018 AFR_19925 23733db75c3b6976ece168744472c548 219 SMART SM00448 1 120 5.3E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19925 23733db75c3b6976ece168744472c548 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_19925 23733db75c3b6976ece168744472c548 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_19925 23733db75c3b6976ece168744472c548 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_19925 23733db75c3b6976ece168744472c548 219 SMART SM00421 148 211 4.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_19925 23733db75c3b6976ece168744472c548 219 SUPERFAMILY SSF46894 149 196 3.4E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_19925 23733db75c3b6976ece168744472c548 219 SUPERFAMILY SSF52172 2 164 7.02E-19 T 12-10-2018 IPR011006 CheY-like superfamily AFR_07455 f65aefbe4627371c22868aa38cbfd323 163 Gene3D G3DSA:3.10.310.50 41 163 6.8E-9 T 12-10-2018 AFR_07455 f65aefbe4627371c22868aa38cbfd323 163 Pfam PF17174 Domain of unknown function (DUF5130) 44 154 1.2E-25 T 12-10-2018 IPR033437 Protein of unknown function DUF5130 AFR_37475 8d70b49cc143574a58a8e10a58924112 160 SMART SM00347 28 128 3.7E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_37475 8d70b49cc143574a58a8e10a58924112 160 Pfam PF01047 MarR family 35 92 2.2E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_37475 8d70b49cc143574a58a8e10a58924112 160 Gene3D G3DSA:1.10.10.10 2 160 6.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37475 8d70b49cc143574a58a8e10a58924112 160 SUPERFAMILY SSF46785 9 143 2.32E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_37475 8d70b49cc143574a58a8e10a58924112 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_37475 8d70b49cc143574a58a8e10a58924112 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_37475 8d70b49cc143574a58a8e10a58924112 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_37475 8d70b49cc143574a58a8e10a58924112 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.8E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_17565 837f0e69d7b299beacbcf6f9c89c155f 381 ProSitePatterns PS00503 Pectinesterase signature 2. 228 237 - T 12-10-2018 IPR033131 Pectinesterase, Asp active site KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 AFR_17565 837f0e69d7b299beacbcf6f9c89c155f 381 Gene3D G3DSA:2.160.20.10 63 381 4.8E-98 T 12-10-2018 IPR012334 Pectin lyase fold AFR_17565 837f0e69d7b299beacbcf6f9c89c155f 381 SUPERFAMILY SSF51126 61 378 5.58E-68 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_17565 837f0e69d7b299beacbcf6f9c89c155f 381 Pfam PF01095 Pectinesterase 65 373 1.8E-43 T 12-10-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 AFR_13040 783fc8177048e744148c3708a761ddbe 197 SUPERFAMILY SSF48498 86 181 3.61E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13040 783fc8177048e744148c3708a761ddbe 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13040 783fc8177048e744148c3708a761ddbe 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13040 783fc8177048e744148c3708a761ddbe 197 Gene3D G3DSA:1.10.357.10 1 196 6.8E-70 T 12-10-2018 AFR_13040 783fc8177048e744148c3708a761ddbe 197 SUPERFAMILY SSF46689 2 85 7.98E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13040 783fc8177048e744148c3708a761ddbe 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 3.3E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_21275 9c4f54ea3509eb00ef7a5654e3320f73 366 Pfam PF07730 Histidine kinase 183 246 1.8E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_21275 9c4f54ea3509eb00ef7a5654e3320f73 366 SUPERFAMILY SSF55874 263 365 1.83E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21275 9c4f54ea3509eb00ef7a5654e3320f73 366 Gene3D G3DSA:3.30.565.10 249 366 9.0E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19125 94b912363736faf0571037d10285bc85 263 Pfam PF04672 S-adenosyl methyltransferase 9 263 2.7E-86 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_19125 94b912363736faf0571037d10285bc85 263 Gene3D G3DSA:3.40.50.150 3 262 1.8E-98 T 12-10-2018 AFR_19125 94b912363736faf0571037d10285bc85 263 PIRSF PIRSF017393 4 263 6.1E-91 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_19125 94b912363736faf0571037d10285bc85 263 SUPERFAMILY SSF53335 10 242 9.22E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_22160 01f4094f921a080d92549f31a0d9b70b 302 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 5 250 1.6E-71 T 12-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain AFR_22160 01f4094f921a080d92549f31a0d9b70b 302 Gene3D G3DSA:3.90.245.10 2 290 3.3E-90 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like AFR_22160 01f4094f921a080d92549f31a0d9b70b 302 SUPERFAMILY SSF53590 5 264 1.44E-78 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like AFR_15960 b0775f47b79ec7646e886c835c330369 273 Gene3D G3DSA:2.160.20.10 17 270 4.9E-8 T 12-10-2018 IPR012334 Pectin lyase fold AFR_15960 b0775f47b79ec7646e886c835c330369 273 SUPERFAMILY SSF51126 32 258 9.24E-12 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_15960 b0775f47b79ec7646e886c835c330369 273 Pfam PF13229 Right handed beta helix region 58 232 2.7E-6 T 12-10-2018 IPR039448 Right handed beta helix domain AFR_07960 7373d5e5469b754a1f57e7dcf86ab4d6 156 Gene3D G3DSA:3.40.390.30 2 151 3.1E-41 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 AFR_07960 7373d5e5469b754a1f57e7dcf86ab4d6 156 SUPERFAMILY SSF55486 3 150 7.57E-40 T 12-10-2018 AFR_07960 7373d5e5469b754a1f57e7dcf86ab4d6 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 149 1.2E-33 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFR_07960 7373d5e5469b754a1f57e7dcf86ab4d6 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 155 21.85 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFR_07960 7373d5e5469b754a1f57e7dcf86ab4d6 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site AFR_07960 7373d5e5469b754a1f57e7dcf86ab4d6 156 Pfam PF02130 Uncharacterized protein family UPF0054 18 147 3.0E-38 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFR_06625 a1c2f62ebf620e29101746ae5c113af9 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 32 47 2.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_06625 a1c2f62ebf620e29101746ae5c113af9 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 2.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_06625 a1c2f62ebf620e29101746ae5c113af9 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 86 2.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_06625 a1c2f62ebf620e29101746ae5c113af9 245 SUPERFAMILY SSF53474 2 242 4.3E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_06625 a1c2f62ebf620e29101746ae5c113af9 245 Gene3D G3DSA:3.40.50.1820 1 244 7.9E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_06625 a1c2f62ebf620e29101746ae5c113af9 245 Pfam PF00561 alpha/beta hydrolase fold 7 230 3.1E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_02320 7e686ba6dc650bc975b0b11994926c24 357 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 39 6.2E-8 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_02320 7e686ba6dc650bc975b0b11994926c24 357 Pfam PF13521 AAA domain 157 332 3.6E-23 T 12-10-2018 IPR038727 NadR/Ttd14, AAA domain AFR_02320 7e686ba6dc650bc975b0b11994926c24 357 Gene3D G3DSA:3.40.50.620 5 154 1.6E-27 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_02320 7e686ba6dc650bc975b0b11994926c24 357 Gene3D G3DSA:3.40.50.300 155 336 1.3E-29 T 12-10-2018 AFR_02320 7e686ba6dc650bc975b0b11994926c24 357 SUPERFAMILY SSF52374 6 155 3.38E-11 T 12-10-2018 AFR_02320 7e686ba6dc650bc975b0b11994926c24 357 SUPERFAMILY SSF52540 155 338 1.97E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18255 6099f4b6064f15255756ace5053fa290 515 SMART SM00267 353 515 6.7E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_18255 6099f4b6064f15255756ace5053fa290 515 SUPERFAMILY SSF48452 180 296 6.9E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18255 6099f4b6064f15255756ace5053fa290 515 SUPERFAMILY SSF55073 369 513 2.9E-36 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_18255 6099f4b6064f15255756ace5053fa290 515 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 513 1.8E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_18255 6099f4b6064f15255756ace5053fa290 515 Gene3D G3DSA:1.25.40.10 23 171 3.5E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18255 6099f4b6064f15255756ace5053fa290 515 Pfam PF00990 Diguanylate cyclase, GGDEF domain 364 512 2.9E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_18255 6099f4b6064f15255756ace5053fa290 515 Gene3D G3DSA:3.30.70.270 353 515 1.3E-42 T 12-10-2018 AFR_18255 6099f4b6064f15255756ace5053fa290 515 SUPERFAMILY SSF48452 29 249 8.91E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_18255 6099f4b6064f15255756ace5053fa290 515 Gene3D G3DSA:1.25.40.10 172 352 3.6E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_35665 dcf62412bfed1133259ade56128da1ef 171 SUPERFAMILY SSF55729 11 153 1.52E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35665 dcf62412bfed1133259ade56128da1ef 171 Gene3D G3DSA:3.40.630.30 2 160 1.8E-49 T 12-10-2018 AFR_35665 dcf62412bfed1133259ade56128da1ef 171 Pfam PF08445 FR47-like protein 70 154 5.1E-25 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_19440 b3f7a5c865d906e98cc12b0f42a047e8 144 SMART SM00347 32 134 3.8E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19440 b3f7a5c865d906e98cc12b0f42a047e8 144 SUPERFAMILY SSF46785 12 128 6.75E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19440 b3f7a5c865d906e98cc12b0f42a047e8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19440 b3f7a5c865d906e98cc12b0f42a047e8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19440 b3f7a5c865d906e98cc12b0f42a047e8 144 Pfam PF12802 MarR family 39 98 5.3E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19440 b3f7a5c865d906e98cc12b0f42a047e8 144 Gene3D G3DSA:1.10.10.10 3 142 1.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17040 8280a061795f7974d11f3a08671bdfe8 176 Gene3D G3DSA:1.10.10.10 116 176 1.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17040 8280a061795f7974d11f3a08671bdfe8 176 Pfam PF08281 Sigma-70, region 4 119 171 2.5E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_17040 8280a061795f7974d11f3a08671bdfe8 176 SUPERFAMILY SSF88659 117 175 5.79E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_17040 8280a061795f7974d11f3a08671bdfe8 176 Gene3D G3DSA:1.10.1740.10 2 104 7.6E-21 T 12-10-2018 AFR_17040 8280a061795f7974d11f3a08671bdfe8 176 SUPERFAMILY SSF88946 2 104 2.35E-20 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_17040 8280a061795f7974d11f3a08671bdfe8 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 175 1.1E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_17040 8280a061795f7974d11f3a08671bdfe8 176 Pfam PF04542 Sigma-70 region 2 28 91 4.2E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_03975 a328bc245caf15cc8271774554f4e9e0 785 SUPERFAMILY SSF53187 46 315 4.29E-49 T 12-10-2018 AFR_03975 a328bc245caf15cc8271774554f4e9e0 785 Gene3D G3DSA:3.40.630.10 46 319 3.0E-58 T 12-10-2018 AFR_03975 a328bc245caf15cc8271774554f4e9e0 785 Pfam PF04389 Peptidase family M28 120 307 4.4E-39 T 12-10-2018 IPR007484 Peptidase M28 AFR_20255 f8e68cb0262edbc9f4bb930ff7845362 265 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 10 246 29.341 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20255 f8e68cb0262edbc9f4bb930ff7845362 265 Gene3D G3DSA:3.20.20.70 2 251 7.4E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_20255 f8e68cb0262edbc9f4bb930ff7845362 265 Pfam PF00290 Tryptophan synthase alpha chain 8 229 2.4E-70 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20255 f8e68cb0262edbc9f4bb930ff7845362 265 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 42 55 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20255 f8e68cb0262edbc9f4bb930ff7845362 265 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 7 229 9.6E-64 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20255 f8e68cb0262edbc9f4bb930ff7845362 265 SUPERFAMILY SSF51366 6 230 6.59E-65 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_16070 229f2d3f20cb36ab80c609b16f08fc2f 282 SUPERFAMILY SSF51735 106 276 2.99E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16070 229f2d3f20cb36ab80c609b16f08fc2f 282 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 279 27.147 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFR_16070 229f2d3f20cb36ab80c609b16f08fc2f 282 Gene3D G3DSA:3.40.50.10860 7 268 6.1E-82 T 12-10-2018 AFR_16070 229f2d3f20cb36ab80c609b16f08fc2f 282 Gene3D G3DSA:3.40.50.720 104 246 6.1E-82 T 12-10-2018 AFR_16070 229f2d3f20cb36ab80c609b16f08fc2f 282 SUPERFAMILY SSF53223 4 105 3.11E-28 T 12-10-2018 AFR_16070 229f2d3f20cb36ab80c609b16f08fc2f 282 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 93 5.4E-25 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFR_32960 1b94e4b91621bb3b29af2c80d78e8b8b 196 Pfam PF12840 Helix-turn-helix domain 15 68 9.4E-10 T 12-10-2018 AFR_32960 1b94e4b91621bb3b29af2c80d78e8b8b 196 Gene3D G3DSA:1.10.10.10 14 126 1.3E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32960 1b94e4b91621bb3b29af2c80d78e8b8b 196 SMART SM00418 14 105 6.4E-4 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_32960 1b94e4b91621bb3b29af2c80d78e8b8b 196 SUPERFAMILY SSF46785 15 111 1.96E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29580 dc5a2243d608660cb735e32272ee30ed 437 SUPERFAMILY SSF52540 32 377 1.63E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29580 dc5a2243d608660cb735e32272ee30ed 437 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 5 412 2.5E-139 T 12-10-2018 IPR021228 Protein of unknown function DUF2791 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 SUPERFAMILY SSF52540 4 578 1.06E-115 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Pfam PF13245 AAA domain 14 259 1.3E-36 T 12-10-2018 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Gene3D G3DSA:1.10.10.160 109 192 3.0E-72 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Pfam PF13361 UvrD-like helicase C-terminal domain 281 406 4.8E-16 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Gene3D G3DSA:3.40.50.300 465 581 2.9E-26 T 12-10-2018 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Pfam PF00570 HRDC domain 633 698 4.7E-20 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Gene3D G3DSA:1.10.150.80 626 702 1.0E-20 T 12-10-2018 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 SMART SM00341 629 711 5.4E-14 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Gene3D G3DSA:3.40.50.300 284 407 6.7E-20 T 12-10-2018 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 SUPERFAMILY SSF47819 623 701 3.71E-21 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Gene3D G3DSA:3.40.50.300 10 272 3.0E-72 T 12-10-2018 AFR_38355 1e5049128bde1a4c049062111b65ff47 714 Pfam PF13361 UvrD-like helicase C-terminal domain 437 559 3.6E-24 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 SMART SM00448 2 112 7.9E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 SUPERFAMILY SSF46894 125 225 1.59E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 Gene3D G3DSA:1.10.10.10 128 228 1.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 SMART SM00862 149 225 3.5E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 Pfam PF00072 Response regulator receiver domain 5 113 3.4E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 3.1E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 Gene3D G3DSA:3.40.50.2300 1 127 7.6E-37 T 12-10-2018 AFR_40600 0f04c778269ca5248a3fee9e6fa3e851 232 SUPERFAMILY SSF52172 2 125 1.85E-40 T 12-10-2018 IPR011006 CheY-like superfamily AFR_10100 42714854c2b06f709807f7fcd6df97a2 236 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 5 211 6.7E-33 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFR_10100 42714854c2b06f709807f7fcd6df97a2 236 SMART SM00464 4 211 1.3E-35 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFR_10100 42714854c2b06f709807f7fcd6df97a2 236 Gene3D G3DSA:1.20.58.1480 141 217 8.5E-7 T 12-10-2018 AFR_10100 42714854c2b06f709807f7fcd6df97a2 236 SUPERFAMILY SSF88697 5 210 1.39E-46 T 12-10-2018 IPR015947 PUA-like superfamily AFR_10100 42714854c2b06f709807f7fcd6df97a2 236 Gene3D G3DSA:2.30.130.40 2 129 7.3E-34 T 12-10-2018 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 SUPERFAMILY SSF51569 3 299 3.05E-84 T 12-10-2018 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 14 341 3.9E-143 T 12-10-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 Pfam PF08666 SAF domain 290 345 4.7E-9 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 Pfam PF03102 NeuB family 34 273 4.1E-88 T 12-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 SMART SM00858 289 346 9.5E-6 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 Gene3D G3DSA:3.90.1210.10 290 346 3.0E-15 T 12-10-2018 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 Gene3D G3DSA:3.20.20.70 1 275 1.1E-91 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_02805 eaa6436100b981533c424a5b20fa42c8 346 SUPERFAMILY SSF51269 286 346 3.77E-14 T 12-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 Pfam PF00106 short chain dehydrogenase 6 209 1.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 4.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 SUPERFAMILY SSF51735 3 240 8.89E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.8E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 3.8E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.8E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.8E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 3.8E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12185 25c03b4c98875c6966dcd6b15499f599 244 Gene3D G3DSA:3.40.50.720 1 243 4.2E-70 T 12-10-2018 AFR_16865 ff474c1115ea8be20c26535228701972 405 SUPERFAMILY SSF51735 4 227 1.06E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16865 ff474c1115ea8be20c26535228701972 405 Gene3D G3DSA:3.40.50.720 111 230 7.0E-44 T 12-10-2018 AFR_16865 ff474c1115ea8be20c26535228701972 405 Gene3D G3DSA:3.40.50.720 1 110 1.8E-25 T 12-10-2018 AFR_16865 ff474c1115ea8be20c26535228701972 405 PRINTS PR00084 Mannitol dehydrogenase signature 200 215 1.0E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_16865 ff474c1115ea8be20c26535228701972 405 PRINTS PR00084 Mannitol dehydrogenase signature 170 183 1.0E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_16865 ff474c1115ea8be20c26535228701972 405 PRINTS PR00084 Mannitol dehydrogenase signature 131 144 1.0E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_16865 ff474c1115ea8be20c26535228701972 405 PRINTS PR00084 Mannitol dehydrogenase signature 7 17 1.0E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_16865 ff474c1115ea8be20c26535228701972 405 Gene3D G3DSA:1.10.1040.10 231 405 2.1E-46 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_16865 ff474c1115ea8be20c26535228701972 405 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 170 182 - T 12-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFR_16865 ff474c1115ea8be20c26535228701972 405 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 6 140 9.1E-18 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_16865 ff474c1115ea8be20c26535228701972 405 SUPERFAMILY SSF48179 232 403 1.09E-38 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_16865 ff474c1115ea8be20c26535228701972 405 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 168 361 9.7E-52 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 AFR_34020 b601cfb9ef2cf079cb162112168cf049 249 Gene3D G3DSA:3.10.520.20 94 247 3.1E-43 T 12-10-2018 AFR_34020 b601cfb9ef2cf079cb162112168cf049 249 Pfam PF02424 ApbE family 95 222 4.0E-35 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 AFR_34020 b601cfb9ef2cf079cb162112168cf049 249 Pfam PF02424 ApbE family 8 91 2.1E-11 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 AFR_34020 b601cfb9ef2cf079cb162112168cf049 249 Gene3D G3DSA:3.10.520.20 1 93 1.3E-16 T 12-10-2018 AFR_34020 b601cfb9ef2cf079cb162112168cf049 249 SUPERFAMILY SSF143631 3 245 9.29E-62 T 12-10-2018 IPR003374 ApbE-like superfamily AFR_23810 eb7d54017a03af8ee1da42a534b1e6a0 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.2E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23810 eb7d54017a03af8ee1da42a534b1e6a0 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23810 eb7d54017a03af8ee1da42a534b1e6a0 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23810 eb7d54017a03af8ee1da42a534b1e6a0 228 SUPERFAMILY SSF46689 3 79 8.98E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_23810 eb7d54017a03af8ee1da42a534b1e6a0 228 Gene3D G3DSA:1.10.357.10 4 187 7.4E-25 T 12-10-2018 AFR_28805 feb4e5c6ac5b8a12e09e7d5f8f73dcbf 457 Pfam PF00561 alpha/beta hydrolase fold 56 429 4.4E-28 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28805 feb4e5c6ac5b8a12e09e7d5f8f73dcbf 457 SUPERFAMILY SSF53474 33 428 8.53E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18150 5fec57d129706220a273c5351a4b7826 423 SUPERFAMILY SSF53448 40 313 1.1E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_18150 5fec57d129706220a273c5351a4b7826 423 Pfam PF13641 Glycosyltransferase like family 2 49 272 8.8E-44 T 12-10-2018 AFR_18150 5fec57d129706220a273c5351a4b7826 423 Gene3D G3DSA:3.90.550.10 43 262 1.6E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_39095 8a9e7439e5a5060a23bab6b0867c051a 193 Pfam PF05685 Putative restriction endonuclease 19 184 7.4E-25 T 12-10-2018 IPR008538 Domain of unknown function DUF820 AFR_39095 8a9e7439e5a5060a23bab6b0867c051a 193 Gene3D G3DSA:3.90.1570.10 14 187 2.4E-17 T 12-10-2018 AFR_39095 8a9e7439e5a5060a23bab6b0867c051a 193 SUPERFAMILY SSF52980 18 186 1.98E-19 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_17190 c096362a8b13814103f89b04a88be35a 589 Gene3D G3DSA:3.30.565.10 422 576 2.8E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17190 c096362a8b13814103f89b04a88be35a 589 Gene3D G3DSA:1.10.287.130 312 417 2.3E-13 T 12-10-2018 AFR_17190 c096362a8b13814103f89b04a88be35a 589 Pfam PF00512 His Kinase A (phospho-acceptor) domain 355 418 3.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_17190 c096362a8b13814103f89b04a88be35a 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 460 571 1.4E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17190 c096362a8b13814103f89b04a88be35a 589 Pfam PF03924 CHASE domain 62 240 3.1E-27 T 12-10-2018 IPR006189 CHASE domain AFR_17190 c096362a8b13814103f89b04a88be35a 589 SMART SM00387 460 573 6.9E-39 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17190 c096362a8b13814103f89b04a88be35a 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 514 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_17190 c096362a8b13814103f89b04a88be35a 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_17190 c096362a8b13814103f89b04a88be35a 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 570 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_17190 c096362a8b13814103f89b04a88be35a 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 551 5.1E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_17190 c096362a8b13814103f89b04a88be35a 589 SMART SM00388 351 419 8.4E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_17190 c096362a8b13814103f89b04a88be35a 589 Gene3D G3DSA:3.30.450.350 63 256 1.2E-9 T 12-10-2018 AFR_17190 c096362a8b13814103f89b04a88be35a 589 SUPERFAMILY SSF47384 344 419 2.16E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_17190 c096362a8b13814103f89b04a88be35a 589 SMART SM01079 59 248 2.2E-10 T 12-10-2018 IPR006189 CHASE domain AFR_17190 c096362a8b13814103f89b04a88be35a 589 SUPERFAMILY SSF55874 408 571 3.98E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 Hamap MF_00220_B Dihydroorotase [pyrC]. 4 416 41.943 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 31 413 1.6E-130 T 12-10-2018 AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 Pfam PF01979 Amidohydrolase family 44 411 6.0E-19 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 SUPERFAMILY SSF51338 2 419 1.11E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 SUPERFAMILY SSF51556 47 357 1.67E-99 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 ProSitePatterns PS00483 Dihydroorotase signature 2. 297 308 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 Gene3D G3DSA:2.30.40.10 15 411 1.1E-130 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_30625 bba79c5f45f0de56f37a3645f7e31b27 421 Gene3D G3DSA:3.20.20.140 48 359 1.1E-130 T 12-10-2018 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 126 136 - T 12-10-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 Gene3D G3DSA:2.60.120.180 44 237 1.1E-78 T 12-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 PRINTS PR00911 Glycosyl hydrolase family 11 signature 154 160 9.4E-16 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 PRINTS PR00911 Glycosyl hydrolase family 11 signature 174 179 9.4E-16 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 PRINTS PR00911 Glycosyl hydrolase family 11 signature 179 188 9.4E-16 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 PRINTS PR00911 Glycosyl hydrolase family 11 signature 126 136 9.4E-16 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 PRINTS PR00911 Glycosyl hydrolase family 11 signature 116 125 9.4E-16 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 PRINTS PR00911 Glycosyl hydrolase family 11 signature 202 210 9.4E-16 T 12-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 SUPERFAMILY SSF49899 45 234 1.06E-75 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 SUPERFAMILY SSF49384 253 342 3.49E-17 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 Gene3D G3DSA:2.60.40.290 253 342 2.9E-21 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 Pfam PF00457 Glycosyl hydrolases family 11 55 231 5.7E-77 T 12-10-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_14765 8f9220af289a2032e598af18c3bc6a5d 342 SMART SM00637 256 339 8.1E-16 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 SMART SM00283 448 702 2.4E-42 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 Gene3D G3DSA:3.30.450.20 227 366 4.0E-6 T 12-10-2018 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 SMART SM00304 388 440 6.8E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 623 652 1.8E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 575 604 1.8E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 546 573 1.8E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 385 1.8E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 Pfam PF17201 Cache 3/Cache 2 fusion domain 39 358 1.4E-70 T 12-10-2018 IPR033462 Cache 3/Cache 2 fusion domain AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 Pfam PF00672 HAMP domain 388 436 1.6E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 Gene3D G3DSA:1.10.287.950 388 703 2.9E-57 T 12-10-2018 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 SUPERFAMILY SSF58104 408 701 1.44E-56 T 12-10-2018 AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 SUPERFAMILY SSF103190 126 239 1.14E-12 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFR_08760 641e9572a04a14d1e37147ae44a8d5b3 703 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 506 673 7.6E-32 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 SUPERFAMILY SSF103473 214 474 3.4E-25 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_42040 f782919300ef9135986e74b8e6da93d5 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 85 107 1.3E-8 T 12-10-2018 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 1.3E-8 T 12-10-2018 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.3E-8 T 12-10-2018 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 172 196 1.3E-8 T 12-10-2018 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 SUPERFAMILY SSF103473 13 203 5.62E-47 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_42040 f782919300ef9135986e74b8e6da93d5 489 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 92 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 431 1.7E-72 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 Gene3D G3DSA:1.20.1720.10 23 232 2.8E-50 T 12-10-2018 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 Gene3D G3DSA:1.20.1250.20 268 473 1.1E-15 T 12-10-2018 AFR_42040 f782919300ef9135986e74b8e6da93d5 489 Pfam PF07690 Major Facilitator Superfamily 26 421 1.2E-57 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_13520 75197b2e06e35954790d70ce4cd14d53 284 SUPERFAMILY SSF47413 29 77 4.57E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_13520 75197b2e06e35954790d70ce4cd14d53 284 Gene3D G3DSA:3.30.450.180 105 280 8.9E-10 T 12-10-2018 AFR_13520 75197b2e06e35954790d70ce4cd14d53 284 Pfam PF13560 Helix-turn-helix domain 5 84 9.0E-15 T 12-10-2018 AFR_13520 75197b2e06e35954790d70ce4cd14d53 284 Gene3D G3DSA:1.10.260.40 24 96 1.1E-5 T 12-10-2018 AFR_13520 75197b2e06e35954790d70ce4cd14d53 284 SMART SM00530 9 81 3.5E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 SUPERFAMILY SSF46548 5 153 3.14E-36 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 129 2.5E-23 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 459 9.9E-25 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 Gene3D G3DSA:3.50.50.60 279 472 2.5E-18 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 SUPERFAMILY SSF51971 378 470 2.59E-13 T 12-10-2018 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 SUPERFAMILY SSF51971 142 404 2.12E-61 T 12-10-2018 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 Gene3D G3DSA:1.10.1060.10 10 139 1.3E-21 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 477 1.5E-183 T 12-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 PRINTS PR00419 Adrenodoxin reductase family signature 144 166 1.1E-23 T 12-10-2018 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 PRINTS PR00419 Adrenodoxin reductase family signature 284 298 1.1E-23 T 12-10-2018 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 PRINTS PR00419 Adrenodoxin reductase family signature 167 180 1.1E-23 T 12-10-2018 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 PRINTS PR00419 Adrenodoxin reductase family signature 209 219 1.1E-23 T 12-10-2018 AFR_10340 057dba32f0f92a1961a3cb2c62c80026 491 Gene3D G3DSA:3.50.50.60 141 269 8.4E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37435 4810694fe345e7e32c06e4df54b111f4 298 SUPERFAMILY SSF52540 1 132 1.01E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37435 4810694fe345e7e32c06e4df54b111f4 298 Gene3D G3DSA:3.40.50.1000 163 298 6.6E-53 T 12-10-2018 IPR023214 HAD superfamily AFR_37435 4810694fe345e7e32c06e4df54b111f4 298 Pfam PF13671 AAA domain 4 134 1.9E-18 T 12-10-2018 AFR_37435 4810694fe345e7e32c06e4df54b111f4 298 Gene3D G3DSA:3.40.50.300 1 136 8.6E-35 T 12-10-2018 AFR_37435 4810694fe345e7e32c06e4df54b111f4 298 SUPERFAMILY SSF56784 163 297 2.91E-23 T 12-10-2018 IPR036412 HAD-like superfamily AFR_02820 e544c2ef82aa0e750676584c703b303b 340 SUPERFAMILY SSF51126 10 323 5.5E-16 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_02820 e544c2ef82aa0e750676584c703b303b 340 Gene3D G3DSA:2.160.20.10 126 338 2.8E-5 T 12-10-2018 IPR012334 Pectin lyase fold AFR_34735 76daa6e9fb268f73ad253292b3e303ad 530 SUPERFAMILY SSF56801 16 526 1.83E-157 T 12-10-2018 AFR_34735 76daa6e9fb268f73ad253292b3e303ad 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_34735 76daa6e9fb268f73ad253292b3e303ad 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 513 7.8E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_34735 76daa6e9fb268f73ad253292b3e303ad 530 Gene3D G3DSA:3.40.50.12780 9 423 7.9E-120 T 12-10-2018 AFR_34735 76daa6e9fb268f73ad253292b3e303ad 530 Gene3D G3DSA:3.30.300.30 424 529 1.9E-30 T 12-10-2018 AFR_34735 76daa6e9fb268f73ad253292b3e303ad 530 Pfam PF00501 AMP-binding enzyme 22 428 1.6E-108 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_04575 9a0a37ac0177cd2012ecb3e71cb4558a 135 Pfam PF00410 Ribosomal protein S8 5 135 1.8E-49 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04575 9a0a37ac0177cd2012ecb3e71cb4558a 135 SUPERFAMILY SSF56047 3 135 2.49E-43 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04575 9a0a37ac0177cd2012ecb3e71cb4558a 135 Gene3D G3DSA:3.30.1370.30 4 81 5.8E-26 T 12-10-2018 AFR_04575 9a0a37ac0177cd2012ecb3e71cb4558a 135 Gene3D G3DSA:3.30.1490.10 82 135 3.5E-25 T 12-10-2018 AFR_04575 9a0a37ac0177cd2012ecb3e71cb4558a 135 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 135 31.852 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04575 9a0a37ac0177cd2012ecb3e71cb4558a 135 ProSitePatterns PS00053 Ribosomal protein S8 signature. 105 122 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_11270 3eb2730ae0f1ab5f95682c46b25daab0 495 SUPERFAMILY SSF55874 264 387 3.14E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11270 3eb2730ae0f1ab5f95682c46b25daab0 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 378 9.3E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11270 3eb2730ae0f1ab5f95682c46b25daab0 495 SMART SM00387 267 380 1.6E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_11270 3eb2730ae0f1ab5f95682c46b25daab0 495 Gene3D G3DSA:3.30.565.10 233 379 2.5E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12605 a3ef8e7bd59f372b397ae1c497e40a5a 277 SUPERFAMILY SSF47413 29 78 1.06E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_12605 a3ef8e7bd59f372b397ae1c497e40a5a 277 Gene3D G3DSA:3.30.450.180 105 271 6.3E-18 T 12-10-2018 AFR_12605 a3ef8e7bd59f372b397ae1c497e40a5a 277 Gene3D G3DSA:1.10.260.40 1 84 5.3E-6 T 12-10-2018 AFR_12605 a3ef8e7bd59f372b397ae1c497e40a5a 277 SMART SM00530 8 81 4.7E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_12605 a3ef8e7bd59f372b397ae1c497e40a5a 277 Pfam PF13560 Helix-turn-helix domain 4 84 4.4E-15 T 12-10-2018 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 SMART SM00421 788 845 3.3E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 ProSitePatterns PS00622 LuxR-type HTH domain signature. 805 832 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 Pfam PF13191 AAA ATPase domain 5 139 1.3E-14 T 12-10-2018 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 Gene3D G3DSA:1.25.40.10 508 679 2.0E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 SUPERFAMILY SSF46894 782 848 2.35E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 805 821 8.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 821 833 8.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 791 805 8.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 Gene3D G3DSA:1.25.40.10 333 507 7.4E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 SUPERFAMILY SSF48452 390 597 4.6E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 Pfam PF00196 Bacterial regulatory proteins, luxR family 791 844 4.3E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 Gene3D G3DSA:1.10.10.10 739 851 2.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08475 4c0c67aece494816aa24dff9a6d55376 864 SUPERFAMILY SSF52540 10 188 5.92E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 Pfam PF00512 His Kinase A (phospho-acceptor) domain 288 353 5.3E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 Gene3D G3DSA:1.10.287.130 197 261 1.1E-5 T 12-10-2018 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 SUPERFAMILY SSF47384 277 354 1.18E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 SUPERFAMILY SSF158472 196 247 7.06E-6 T 12-10-2018 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 SUPERFAMILY SSF55874 343 517 7.47E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 513 3.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 494 3.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 451 3.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 SMART SM00387 399 516 6.3E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 Gene3D G3DSA:1.10.287.130 281 354 1.7E-23 T 12-10-2018 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 SMART SM00304 193 251 1.6E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 Pfam PF00672 HAMP domain 198 247 3.1E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 399 514 2.3E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 Gene3D G3DSA:3.30.565.10 367 516 3.9E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_37940 c26b3865ce7cd4a1e14ead26d9aa7f31 520 SMART SM00388 287 354 3.8E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13095 e7776471b610acf95ea1d129fdeb8424 248 SUPERFAMILY SSF53474 1 246 9.14E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13095 e7776471b610acf95ea1d129fdeb8424 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 9.7E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13095 e7776471b610acf95ea1d129fdeb8424 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 9.7E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13095 e7776471b610acf95ea1d129fdeb8424 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 9.7E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13095 e7776471b610acf95ea1d129fdeb8424 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 192 206 9.7E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13095 e7776471b610acf95ea1d129fdeb8424 248 Pfam PF12697 Alpha/beta hydrolase family 2 240 1.6E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13095 e7776471b610acf95ea1d129fdeb8424 248 Gene3D G3DSA:3.40.50.1820 1 248 1.4E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_24925 e56c28ac8738033164de199dde4bcd39 918 SUPERFAMILY SSF48452 486 620 3.34E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 SUPERFAMILY SSF48452 685 832 6.68E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 SUPERFAMILY SSF52540 39 252 4.42E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Gene3D G3DSA:1.25.40.10 723 902 5.7E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Gene3D G3DSA:1.25.40.10 436 624 2.7E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Gene3D G3DSA:1.25.40.10 625 713 2.5E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Pfam PF13424 Tetratricopeptide repeat 528 592 2.8E-13 T 12-10-2018 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Pfam PF13424 Tetratricopeptide repeat 626 678 3.7E-9 T 12-10-2018 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Pfam PF13374 Tetratricopeptide repeat 774 813 1.3E-4 T 12-10-2018 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Pfam PF13374 Tetratricopeptide repeat 734 772 0.015 T 12-10-2018 AFR_24925 e56c28ac8738033164de199dde4bcd39 918 Gene3D G3DSA:3.40.50.300 37 191 1.4E-10 T 12-10-2018 AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 Gene3D G3DSA:3.10.50.10 390 450 2.6E-127 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 Gene3D G3DSA:2.10.10.20 31 83 5.1E-18 T 12-10-2018 AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 Pfam PF00704 Glycosyl hydrolases family 18 123 475 1.2E-69 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 ProSitePatterns PS01095 Chitinases family 18 active site. 256 264 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 Gene3D G3DSA:3.20.20.80 125 478 2.6E-127 T 12-10-2018 AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 SUPERFAMILY SSF54556 387 446 3.92E-12 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 SUPERFAMILY SSF51445 115 489 3.77E-77 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 SMART SM00495 34 79 2.5E-13 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 SUPERFAMILY SSF51055 31 82 6.28E-14 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_09645 5cfd070c81974e0bba88013a360a2ef2 490 SMART SM00636 121 475 1.3E-103 T 12-10-2018 IPR011583 Chitinase II GO:0008061 AFR_14050 6a9ca993eb1170befb99547e89d50c61 198 Gene3D G3DSA:2.60.40.1220 24 122 1.0E-29 T 12-10-2018 AFR_14050 6a9ca993eb1170befb99547e89d50c61 198 SUPERFAMILY SSF81296 23 117 7.0E-24 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_14050 6a9ca993eb1170befb99547e89d50c61 198 Pfam PF04234 CopC domain 24 117 3.2E-26 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 AFR_01420 d569b33de09b8685f6f33920e0bf7830 208 Pfam PF02441 Flavoprotein 5 180 5.1E-15 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFR_01420 d569b33de09b8685f6f33920e0bf7830 208 Gene3D G3DSA:3.40.50.1950 1 201 2.3E-67 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFR_01420 d569b33de09b8685f6f33920e0bf7830 208 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 6 198 4.4E-43 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like AFR_01420 d569b33de09b8685f6f33920e0bf7830 208 SUPERFAMILY SSF52507 5 200 6.02E-42 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFR_02050 96f96c55431cba3711cb608a01b7d9f7 137 ProSitePatterns PS00893 Nudix box signature. 30 51 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_02050 96f96c55431cba3711cb608a01b7d9f7 137 Gene3D G3DSA:3.90.79.10 1 121 4.9E-31 T 12-10-2018 AFR_02050 96f96c55431cba3711cb608a01b7d9f7 137 SUPERFAMILY SSF55811 2 112 3.52E-30 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_02050 96f96c55431cba3711cb608a01b7d9f7 137 PRINTS PR00502 NUDIX hydrolase family signature 25 39 5.8E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_02050 96f96c55431cba3711cb608a01b7d9f7 137 PRINTS PR00502 NUDIX hydrolase family signature 39 54 5.8E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_02050 96f96c55431cba3711cb608a01b7d9f7 137 Pfam PF00293 NUDIX domain 3 112 3.1E-21 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_29125 890acae410a30c0437a5fa12a28189cc 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_29125 890acae410a30c0437a5fa12a28189cc 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 4.3E-29 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_29125 890acae410a30c0437a5fa12a28189cc 343 Gene3D G3DSA:3.40.50.720 151 283 1.1E-90 T 12-10-2018 AFR_29125 890acae410a30c0437a5fa12a28189cc 343 SUPERFAMILY SSF50129 3 170 7.76E-46 T 12-10-2018 IPR011032 GroES-like superfamily AFR_29125 890acae410a30c0437a5fa12a28189cc 343 Gene3D G3DSA:3.90.180.10 18 328 1.1E-90 T 12-10-2018 AFR_29125 890acae410a30c0437a5fa12a28189cc 343 SMART SM00829 9 335 2.8E-5 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_29125 890acae410a30c0437a5fa12a28189cc 343 Pfam PF00107 Zinc-binding dehydrogenase 173 298 1.2E-20 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_29125 890acae410a30c0437a5fa12a28189cc 343 SUPERFAMILY SSF51735 141 300 2.23E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_00615 16e623a686ef0153c7650298846cda41 162 SUPERFAMILY SSF88946 5 87 2.47E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_00615 16e623a686ef0153c7650298846cda41 162 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 160 2.7E-49 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_00615 16e623a686ef0153c7650298846cda41 162 Gene3D G3DSA:1.10.1740.10 4 77 6.6E-9 T 12-10-2018 AFR_00615 16e623a686ef0153c7650298846cda41 162 Gene3D G3DSA:1.10.10.10 80 161 6.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00615 16e623a686ef0153c7650298846cda41 162 SUPERFAMILY SSF88659 97 157 1.36E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_00615 16e623a686ef0153c7650298846cda41 162 Pfam PF08281 Sigma-70, region 4 102 154 1.0E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_00615 16e623a686ef0153c7650298846cda41 162 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 158 1.4E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_00615 16e623a686ef0153c7650298846cda41 162 Pfam PF04542 Sigma-70 region 2 11 73 2.5E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_15800 080be66e7f77f2783c46411b84bd8623 289 Gene3D G3DSA:3.40.50.1820 1 287 5.4E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15800 080be66e7f77f2783c46411b84bd8623 289 SUPERFAMILY SSF53474 4 258 4.35E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15800 080be66e7f77f2783c46411b84bd8623 289 Pfam PF12697 Alpha/beta hydrolase family 45 261 4.8E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_31315 5aefb1b9e0e141f1177ec2941f3ba0ea 302 SMART SM00382 28 203 2.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_31315 5aefb1b9e0e141f1177ec2941f3ba0ea 302 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_31315 5aefb1b9e0e141f1177ec2941f3ba0ea 302 SUPERFAMILY SSF52540 3 223 1.1E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31315 5aefb1b9e0e141f1177ec2941f3ba0ea 302 Pfam PF00005 ABC transporter 20 155 3.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31315 5aefb1b9e0e141f1177ec2941f3ba0ea 302 Gene3D G3DSA:3.40.50.300 1 227 2.4E-64 T 12-10-2018 AFR_28300 6c9bbf4ad665857df5cbcc41d9d0ccef 295 Pfam PF01145 SPFH domain / Band 7 family 20 232 2.8E-7 T 12-10-2018 IPR001107 Band 7 domain AFR_24820 702c991ac84aed61ccae900c88ee1912 476 Gene3D G3DSA:1.10.1040.10 182 435 1.4E-98 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 SUPERFAMILY SSF51735 5 178 2.9E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24820 702c991ac84aed61ccae900c88ee1912 476 PIRSF PIRSF000109 1 476 3.3E-198 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 6 467 8.8E-205 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 255 267 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 Gene3D G3DSA:1.20.5.320 436 470 7.9E-18 T 12-10-2018 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 SUPERFAMILY SSF48179 178 470 2.83E-116 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 6.6E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 6.6E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 251 278 6.6E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 6.6E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 6.6E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 6.6E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 Gene3D G3DSA:3.40.50.720 1 181 2.6E-55 T 12-10-2018 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 467 2.7E-122 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 SMART SM01350 180 468 7.2E-200 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFR_24820 702c991ac84aed61ccae900c88ee1912 476 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 173 1.1E-49 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_00290 d75c12a0fe62e7ca2ceae2fc6de35c83 462 Pfam PF00069 Protein kinase domain 12 261 5.3E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_00290 d75c12a0fe62e7ca2ceae2fc6de35c83 462 SUPERFAMILY SSF56112 9 310 1.48E-75 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_00290 d75c12a0fe62e7ca2ceae2fc6de35c83 462 Gene3D G3DSA:1.10.510.10 93 274 3.4E-48 T 12-10-2018 AFR_00290 d75c12a0fe62e7ca2ceae2fc6de35c83 462 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_00290 d75c12a0fe62e7ca2ceae2fc6de35c83 462 Gene3D G3DSA:3.30.200.20 2 91 6.3E-30 T 12-10-2018 AFR_00290 d75c12a0fe62e7ca2ceae2fc6de35c83 462 SMART SM00220 12 269 3.0E-55 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_00290 d75c12a0fe62e7ca2ceae2fc6de35c83 462 PIRSF PIRSF000654 17 266 7.5E-23 T 12-10-2018 AFR_42555 5840726743a6c6a5233481b4cab18803 117 SUPERFAMILY SSF55021 1 48 1.01E-6 T 12-10-2018 AFR_42555 5840726743a6c6a5233481b4cab18803 117 Pfam PF13840 ACT domain 48 109 4.2E-19 T 12-10-2018 IPR027795 CASTOR, ACT domain AFR_42555 5840726743a6c6a5233481b4cab18803 117 PIRSF PIRSF008459 1 117 2.5E-25 T 12-10-2018 IPR016540 Uncharacterised conserved protein UCP008459 AFR_42555 5840726743a6c6a5233481b4cab18803 117 Gene3D G3DSA:3.30.2130.10 1 117 2.1E-40 T 12-10-2018 AFR_42555 5840726743a6c6a5233481b4cab18803 117 SUPERFAMILY SSF55021 51 115 5.42E-16 T 12-10-2018 AFR_12035 eb2e93bbec50b123e09fcd02e2c5cd61 106 Pfam PF12840 Helix-turn-helix domain 12 67 6.8E-14 T 12-10-2018 AFR_12035 eb2e93bbec50b123e09fcd02e2c5cd61 106 Gene3D G3DSA:1.10.10.10 2 85 8.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12035 eb2e93bbec50b123e09fcd02e2c5cd61 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.3E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_12035 eb2e93bbec50b123e09fcd02e2c5cd61 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.3E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_12035 eb2e93bbec50b123e09fcd02e2c5cd61 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.3E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_12035 eb2e93bbec50b123e09fcd02e2c5cd61 106 SMART SM00418 9 87 8.7E-24 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_12035 eb2e93bbec50b123e09fcd02e2c5cd61 106 SUPERFAMILY SSF46785 6 87 2.78E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17480 b8b5d2f45cca486e20e4bcda72f9caa1 338 SUPERFAMILY SSF46689 251 301 9.86E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_17480 b8b5d2f45cca486e20e4bcda72f9caa1 338 SUPERFAMILY SSF46689 198 248 2.24E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_17480 b8b5d2f45cca486e20e4bcda72f9caa1 338 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 252 294 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_17480 b8b5d2f45cca486e20e4bcda72f9caa1 338 Pfam PF12833 Helix-turn-helix domain 221 300 1.1E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_17480 b8b5d2f45cca486e20e4bcda72f9caa1 338 Gene3D G3DSA:1.10.10.60 197 313 6.2E-22 T 12-10-2018 AFR_17480 b8b5d2f45cca486e20e4bcda72f9caa1 338 Pfam PF12852 Cupin 2 179 8.3E-32 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFR_17480 b8b5d2f45cca486e20e4bcda72f9caa1 338 SMART SM00342 215 298 8.1E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14600 b824ec24670bae25f4bb1209c108ab5f 317 Gene3D G3DSA:1.10.3720.10 104 312 2.4E-24 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14600 b824ec24670bae25f4bb1209c108ab5f 317 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 30 73 4.7E-14 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFR_14600 b824ec24670bae25f4bb1209c108ab5f 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 316 2.3E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_14600 b824ec24670bae25f4bb1209c108ab5f 317 SUPERFAMILY SSF161098 106 298 8.76E-29 T 12-10-2018 IPR035906 MetI-like superfamily AFR_42610 2ca70f5711ca1083bc380f503169aec9 261 Gene3D G3DSA:3.75.10.10 4 257 2.5E-48 T 12-10-2018 AFR_42610 2ca70f5711ca1083bc380f503169aec9 261 SUPERFAMILY SSF55909 2 259 8.44E-45 T 12-10-2018 AFR_42610 2ca70f5711ca1083bc380f503169aec9 261 Pfam PF02274 Amidinotransferase 53 259 7.6E-14 T 12-10-2018 AFR_42795 b7a5de2e4525c667a01efedfeacf887c 269 Pfam PF04607 Region found in RelA / SpoT proteins 112 233 4.4E-9 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 AFR_42795 b7a5de2e4525c667a01efedfeacf887c 269 SUPERFAMILY SSF81301 96 258 2.78E-13 T 12-10-2018 AFR_30270 9bddf853ead607744d92d36d9adc2590 223 SMART SM00100 1 115 6.7E-9 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_30270 9bddf853ead607744d92d36d9adc2590 223 Gene3D G3DSA:2.60.120.10 1 130 1.5E-25 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_30270 9bddf853ead607744d92d36d9adc2590 223 SUPERFAMILY SSF46785 134 212 2.38E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30270 9bddf853ead607744d92d36d9adc2590 223 Pfam PF00027 Cyclic nucleotide-binding domain 16 101 2.8E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_30270 9bddf853ead607744d92d36d9adc2590 223 Pfam PF13545 Crp-like helix-turn-helix domain 136 208 2.0E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFR_30270 9bddf853ead607744d92d36d9adc2590 223 SUPERFAMILY SSF51206 5 126 4.45E-22 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFR_30270 9bddf853ead607744d92d36d9adc2590 223 Gene3D G3DSA:1.10.10.10 133 211 6.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14030 792adc6ee7be04a8cbf7786a9d250fd6 664 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 377 620 1.1E-71 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related AFR_14030 792adc6ee7be04a8cbf7786a9d250fd6 664 Pfam PF05425 Copper resistance protein D 226 323 2.6E-18 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 AFR_41035 199641d41cd378e9c33e9c26a76a6515 133 Pfam PF13577 SnoaL-like domain 7 122 6.1E-17 T 12-10-2018 IPR037401 SnoaL-like domain AFR_41035 199641d41cd378e9c33e9c26a76a6515 133 Gene3D G3DSA:3.10.450.50 2 129 2.8E-26 T 12-10-2018 AFR_41035 199641d41cd378e9c33e9c26a76a6515 133 SUPERFAMILY SSF54427 6 127 1.81E-28 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_38200 876f9c0a42a7ea6e231ba7556170f55d 410 Pfam PF00754 F5/8 type C domain 47 152 1.5E-19 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_38200 876f9c0a42a7ea6e231ba7556170f55d 410 Gene3D G3DSA:2.60.120.260 35 157 1.7E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_38200 876f9c0a42a7ea6e231ba7556170f55d 410 SUPERFAMILY SSF53955 179 408 1.74E-79 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_38200 876f9c0a42a7ea6e231ba7556170f55d 410 Pfam PF01374 Glycosyl hydrolase family 46 193 398 1.0E-92 T 12-10-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 AFR_38200 876f9c0a42a7ea6e231ba7556170f55d 410 Gene3D G3DSA:3.30.386.10 204 298 2.5E-90 T 12-10-2018 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 AFR_38200 876f9c0a42a7ea6e231ba7556170f55d 410 Gene3D G3DSA:1.20.141.10 188 407 2.5E-90 T 12-10-2018 AFR_38200 876f9c0a42a7ea6e231ba7556170f55d 410 SUPERFAMILY SSF49785 45 157 1.13E-22 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_22095 6fad2bb2158602e7e5c6d6c671305a1e 538 Gene3D G3DSA:1.20.1250.20 8 395 1.1E-36 T 12-10-2018 AFR_22095 6fad2bb2158602e7e5c6d6c671305a1e 538 SUPERFAMILY SSF103473 12 397 2.49E-47 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_22095 6fad2bb2158602e7e5c6d6c671305a1e 538 Pfam PF05977 Transmembrane secretion effector 6 520 3.1E-138 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_34700 d173aff240e56605179bbad9c1f3a306 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 257 2.7E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_34700 d173aff240e56605179bbad9c1f3a306 262 SUPERFAMILY SSF161098 2 262 4.71E-68 T 12-10-2018 IPR035906 MetI-like superfamily AFR_34700 d173aff240e56605179bbad9c1f3a306 262 Gene3D G3DSA:1.10.3720.10 1 253 5.8E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20130 b4507a5ff3a29a07a4a39454127b609f 451 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_20130 b4507a5ff3a29a07a4a39454127b609f 451 SUPERFAMILY SSF56112 9 267 2.7E-71 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_20130 b4507a5ff3a29a07a4a39454127b609f 451 Gene3D G3DSA:1.10.510.10 93 273 2.7E-49 T 12-10-2018 AFR_20130 b4507a5ff3a29a07a4a39454127b609f 451 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_20130 b4507a5ff3a29a07a4a39454127b609f 451 Pfam PF00069 Protein kinase domain 12 223 1.3E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_20130 b4507a5ff3a29a07a4a39454127b609f 451 SMART SM00220 12 269 1.3E-51 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_20130 b4507a5ff3a29a07a4a39454127b609f 451 Gene3D G3DSA:3.30.200.20 2 91 7.9E-28 T 12-10-2018 AFR_11990 e65b8b59b258a99f5d2601549854a32f 207 Gene3D G3DSA:1.10.10.60 1 48 1.2E-15 T 12-10-2018 AFR_11990 e65b8b59b258a99f5d2601549854a32f 207 SUPERFAMILY SSF48498 78 184 1.48E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_11990 e65b8b59b258a99f5d2601549854a32f 207 SUPERFAMILY SSF46689 6 73 1.3E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_11990 e65b8b59b258a99f5d2601549854a32f 207 Pfam PF13305 WHG domain 86 160 1.1E-5 T 12-10-2018 IPR025996 WHG domain AFR_11990 e65b8b59b258a99f5d2601549854a32f 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 1.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11990 e65b8b59b258a99f5d2601549854a32f 207 Gene3D G3DSA:1.10.357.10 51 185 8.1E-26 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 1.2E-26 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 Gene3D G3DSA:3.30.390.30 339 453 8.5E-31 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 SUPERFAMILY SSF51905 7 371 4.67E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 1.2E-48 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 319 3.5E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 Gene3D G3DSA:3.50.50.60 8 325 2.3E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PIRSF PIRSF000350 1 450 2.0E-74 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 SUPERFAMILY SSF55424 336 451 4.81E-30 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.4E-17 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 5.4E-17 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 5.4E-17 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 5.4E-17 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 5.4E-17 T 12-10-2018 AFR_00915 23612b49adffa8e3270a7c37631abcbf 453 Gene3D G3DSA:3.50.50.60 147 265 2.3E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_06315 fe8dba771dd6bd3af3d52b67480b65f4 429 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 138 308 6.1E-6 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AFR_06315 fe8dba771dd6bd3af3d52b67480b65f4 429 Gene3D G3DSA:3.20.140.10 9 364 3.9E-104 T 12-10-2018 AFR_06315 fe8dba771dd6bd3af3d52b67480b65f4 429 Gene3D G3DSA:3.20.20.70 150 309 3.9E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_06315 fe8dba771dd6bd3af3d52b67480b65f4 429 SUPERFAMILY SSF51690 138 421 1.31E-77 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFR_06315 fe8dba771dd6bd3af3d52b67480b65f4 429 PIRSF PIRSF000484 2 425 7.3E-99 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AFR_06315 fe8dba771dd6bd3af3d52b67480b65f4 429 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 8 370 1.4E-128 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 AFR_06315 fe8dba771dd6bd3af3d52b67480b65f4 429 SUPERFAMILY SSF54675 7 135 4.84E-41 T 12-10-2018 AFR_07125 b8467f1fd3b0691bb3d2e5d058a0d651 361 SUPERFAMILY SSF55781 159 306 7.85E-15 T 12-10-2018 AFR_07125 b8467f1fd3b0691bb3d2e5d058a0d651 361 Gene3D G3DSA:3.30.450.40 142 305 8.1E-17 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_07125 b8467f1fd3b0691bb3d2e5d058a0d651 361 Pfam PF03861 ANTAR domain 301 352 3.3E-12 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_07125 b8467f1fd3b0691bb3d2e5d058a0d651 361 Gene3D G3DSA:1.10.10.10 306 360 8.5E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07125 b8467f1fd3b0691bb3d2e5d058a0d651 361 SMART SM01012 297 352 1.0E-8 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_23310 c91907aa54114df47898e2ead3feebed 323 SUPERFAMILY SSF53756 135 318 1.82E-10 T 12-10-2018 AFR_23310 c91907aa54114df47898e2ead3feebed 323 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 224 260 6.8E-5 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AFR_23310 c91907aa54114df47898e2ead3feebed 323 Gene3D G3DSA:3.40.50.2000 190 301 1.1E-8 T 12-10-2018 AFR_37135 498503f5d51230c87e1c5b4073481570 1654 SUPERFAMILY SSF53223 794 973 1.63E-25 T 12-10-2018 AFR_37135 498503f5d51230c87e1c5b4073481570 1654 SUPERFAMILY SSF51735 978 1289 9.19E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37135 498503f5d51230c87e1c5b4073481570 1654 PIRSF PIRSF036761 33 1652 0.0 T 12-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 AFR_37135 498503f5d51230c87e1c5b4073481570 1654 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 113 1645 0.0 T 12-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 AFR_20000 300348ca36d131bb298658aabbc7aaa3 485 SUPERFAMILY SSF52091 393 473 4.12E-12 T 12-10-2018 IPR036513 STAS domain superfamily AFR_20000 300348ca36d131bb298658aabbc7aaa3 485 Gene3D G3DSA:3.30.750.24 384 480 1.9E-30 T 12-10-2018 IPR036513 STAS domain superfamily AFR_20000 300348ca36d131bb298658aabbc7aaa3 485 Pfam PF01740 STAS domain 400 472 2.4E-6 T 12-10-2018 IPR002645 STAS domain AFR_20000 300348ca36d131bb298658aabbc7aaa3 485 Pfam PF00916 Sulfate permease family 160 354 2.5E-26 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFR_20000 300348ca36d131bb298658aabbc7aaa3 485 Pfam PF00916 Sulfate permease family 10 140 4.7E-21 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFR_08415 785847a955174b4a0097ce2372f27e4f 230 PRINTS PR00400 Tetracycline repressor protein signature 83 102 4.2E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_08415 785847a955174b4a0097ce2372f27e4f 230 PRINTS PR00400 Tetracycline repressor protein signature 27 50 4.2E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_08415 785847a955174b4a0097ce2372f27e4f 230 Gene3D G3DSA:1.10.357.10 78 227 1.8E-28 T 12-10-2018 AFR_08415 785847a955174b4a0097ce2372f27e4f 230 Gene3D G3DSA:1.10.10.60 5 70 6.7E-25 T 12-10-2018 AFR_08415 785847a955174b4a0097ce2372f27e4f 230 SUPERFAMILY SSF48498 82 227 5.67E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_08415 785847a955174b4a0097ce2372f27e4f 230 SUPERFAMILY SSF46689 8 74 1.05E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_08415 785847a955174b4a0097ce2372f27e4f 230 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 80 224 2.7E-11 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_08415 785847a955174b4a0097ce2372f27e4f 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 1.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_21310 7be9725587da750dff0d6b23cf17b6ec 281 Pfam PF02673 Bacitracin resistance protein BacA 6 267 1.6E-79 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFR_21310 7be9725587da750dff0d6b23cf17b6ec 281 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 273 17.27 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFR_21310 7be9725587da750dff0d6b23cf17b6ec 281 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 266 2.4E-74 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFR_39655 5eefcfe2ad7b995394ea92f325f94876 303 Pfam PF04616 Glycosyl hydrolases family 43 4 289 4.5E-61 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_39655 5eefcfe2ad7b995394ea92f325f94876 303 Gene3D G3DSA:2.115.10.20 1 303 1.9E-82 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_39655 5eefcfe2ad7b995394ea92f325f94876 303 SUPERFAMILY SSF75005 3 303 4.06E-70 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_10815 af00f2d11a6f6103b3e866f0f6193b6c 120 Gene3D G3DSA:3.30.70.1060 3 114 3.8E-20 T 12-10-2018 AFR_10815 af00f2d11a6f6103b3e866f0f6193b6c 120 Pfam PF03795 YCII-related domain 32 99 2.3E-10 T 12-10-2018 IPR005545 YCII-related AFR_10815 af00f2d11a6f6103b3e866f0f6193b6c 120 SUPERFAMILY SSF54909 4 114 3.97E-19 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_24275 fc80f2405d31744ca7f11272c06991c7 235 Gene3D G3DSA:3.30.450.40 7 146 4.6E-8 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_24275 fc80f2405d31744ca7f11272c06991c7 235 SUPERFAMILY SSF55781 24 139 8.83E-10 T 12-10-2018 AFR_14520 c8bc70d4ade059f254c2f41ebc4eefe6 119 Gene3D G3DSA:2.40.100.20 1 115 1.0E-15 T 12-10-2018 AFR_14520 c8bc70d4ade059f254c2f41ebc4eefe6 119 Pfam PF04126 Cyclophilin-like 1 83 1.1E-5 T 12-10-2018 IPR025658 Cyclophilin TM1367-like domain AFR_14520 c8bc70d4ade059f254c2f41ebc4eefe6 119 SUPERFAMILY SSF50891 1 112 2.28E-21 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_03225 c48eb465f3ff1dff2657cfbdac3c1f84 257 SMART SM00382 30 226 5.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03225 c48eb465f3ff1dff2657cfbdac3c1f84 257 Gene3D G3DSA:3.40.50.300 1 245 3.3E-51 T 12-10-2018 AFR_03225 c48eb465f3ff1dff2657cfbdac3c1f84 257 SUPERFAMILY SSF52540 4 234 1.38E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03225 c48eb465f3ff1dff2657cfbdac3c1f84 257 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_03225 c48eb465f3ff1dff2657cfbdac3c1f84 257 Pfam PF00005 ABC transporter 25 179 4.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_33755 fee40eec9da7103449723dfa9e827471 188 Gene3D G3DSA:3.40.50.1820 2 187 1.4E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33755 fee40eec9da7103449723dfa9e827471 188 Pfam PF01738 Dienelactone hydrolase family 4 186 1.6E-15 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFR_33755 fee40eec9da7103449723dfa9e827471 188 SUPERFAMILY SSF53474 4 186 4.22E-18 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_05005 3efce1c2582a439e9d943e4a523590fe 415 Pfam PF02666 Phosphatidylserine decarboxylase 246 409 7.6E-22 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AFR_05005 3efce1c2582a439e9d943e4a523590fe 415 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 213 412 3.0E-44 T 12-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AFR_14385 630123c9a2213aa993b78eec320297b9 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_14385 630123c9a2213aa993b78eec320297b9 192 Gene3D G3DSA:1.10.357.10 1 190 6.0E-40 T 12-10-2018 AFR_14385 630123c9a2213aa993b78eec320297b9 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 3.1E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14385 630123c9a2213aa993b78eec320297b9 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14385 630123c9a2213aa993b78eec320297b9 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14385 630123c9a2213aa993b78eec320297b9 192 SUPERFAMILY SSF46689 4 66 3.18E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_40660 6b8cad4c05bc2e86ed69fd5a85d20c58 107 Pfam PF10724 Protein of unknown function (DUF2516) 13 103 1.4E-26 T 12-10-2018 IPR019662 Protein of unknown function DUF2516 AFR_03180 9b768d963bda6b0633aab940c9e6599e 301 Gene3D G3DSA:3.40.50.1360 51 298 8.9E-65 T 12-10-2018 AFR_03180 9b768d963bda6b0633aab940c9e6599e 301 Pfam PF04198 Putative sugar-binding domain 58 298 2.2E-53 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 AFR_03180 9b768d963bda6b0633aab940c9e6599e 301 Gene3D G3DSA:1.10.10.10 2 50 4.9E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03180 9b768d963bda6b0633aab940c9e6599e 301 SUPERFAMILY SSF100950 59 298 5.76E-54 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_03180 9b768d963bda6b0633aab940c9e6599e 301 Pfam PF04545 Sigma-70, region 4 9 43 5.3E-6 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_18300 cdd47b3a24e601ca8f6e5961a6fb0364 108 Gene3D G3DSA:3.10.180.10 1 106 6.9E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_18300 cdd47b3a24e601ca8f6e5961a6fb0364 108 SUPERFAMILY SSF54593 2 98 6.46E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 3.6E-14 T 12-10-2018 AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.6E-14 T 12-10-2018 AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 3.6E-14 T 12-10-2018 AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 3.6E-14 T 12-10-2018 AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 Gene3D G3DSA:3.50.50.60 5 339 1.0E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 Pfam PF01494 FAD binding domain 2 162 1.5E-9 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 SUPERFAMILY SSF51905 1 366 1.14E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13230 6002cf8ca9aa12b00a16b4bc76bd52b7 374 Gene3D G3DSA:3.30.9.50 38 267 1.0E-62 T 12-10-2018 AFR_33470 044da2b4382f2c6731b9ca4b05a32626 473 Pfam PF02397 Bacterial sugar transferase 280 467 1.2E-67 T 12-10-2018 IPR003362 Bacterial sugar transferase AFR_33470 044da2b4382f2c6731b9ca4b05a32626 473 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 24 473 2.3E-126 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AFR_33470 044da2b4382f2c6731b9ca4b05a32626 473 Pfam PF13727 CoA-binding domain 70 215 1.1E-7 T 12-10-2018 AFR_42225 572ef0f82e655325bdcf55a53a683875 213 SUPERFAMILY SSF55729 11 174 2.28E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_42225 572ef0f82e655325bdcf55a53a683875 213 Pfam PF13302 Acetyltransferase (GNAT) domain 17 164 3.8E-15 T 12-10-2018 IPR000182 GNAT domain AFR_42225 572ef0f82e655325bdcf55a53a683875 213 Gene3D G3DSA:3.40.630.30 2 213 1.1E-56 T 12-10-2018 AFR_21650 e3def89c2e821db0e896e66f9520a48a 388 Pfam PF08495 FIST N domain 34 226 7.1E-35 T 12-10-2018 IPR013702 FIST domain, N-terminal AFR_21650 e3def89c2e821db0e896e66f9520a48a 388 Pfam PF10442 FIST C domain 228 369 7.9E-18 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFR_21650 e3def89c2e821db0e896e66f9520a48a 388 SMART SM01204 228 371 1.7E-21 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFR_21650 e3def89c2e821db0e896e66f9520a48a 388 SMART SM00897 31 227 1.7E-32 T 12-10-2018 IPR013702 FIST domain, N-terminal AFR_31400 914a79c7eb018902ce4f00269f3c9a01 69 Pfam PF11272 Protein of unknown function (DUF3072) 12 67 2.9E-31 T 12-10-2018 IPR021425 Protein of unknown function DUF3072 AFR_20875 c3d2c25f056e36bd91510c4639a5ca80 228 Pfam PF04203 Sortase family 85 226 9.0E-16 T 12-10-2018 IPR005754 Sortase family AFR_20875 c3d2c25f056e36bd91510c4639a5ca80 228 Gene3D G3DSA:2.40.260.10 71 227 7.6E-22 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_20875 c3d2c25f056e36bd91510c4639a5ca80 228 SUPERFAMILY SSF63817 81 227 5.89E-12 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_04580 7899f538e7edbeb361c2c529cf517366 180 SUPERFAMILY SSF56053 84 177 6.54E-35 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 Gene3D G3DSA:3.90.930.12 84 180 9.7E-40 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.336 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 SUPERFAMILY SSF56053 1 83 8.9E-25 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 PRINTS PR00059 Ribosomal protein L6 signature 142 163 1.1E-32 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 PRINTS PR00059 Ribosomal protein L6 signature 72 97 1.1E-32 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 PRINTS PR00059 Ribosomal protein L6 signature 100 116 1.1E-32 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 Pfam PF00347 Ribosomal protein L6 92 165 6.2E-19 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 Pfam PF00347 Ribosomal protein L6 11 83 8.6E-20 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 PIRSF PIRSF002162 1 178 1.3E-45 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.6E-73 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFR_04580 7899f538e7edbeb361c2c529cf517366 180 Gene3D G3DSA:3.90.930.12 1 83 4.4E-31 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 SUPERFAMILY SSF46934 3 56 1.75E-15 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 Gene3D G3DSA:3.30.479.20 57 144 3.8E-16 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 SUPERFAMILY SSF54713 59 274 7.98E-39 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 Gene3D G3DSA:1.10.8.10 1 56 1.5E-23 T 12-10-2018 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 Gene3D G3DSA:3.30.479.20 159 274 4.3E-37 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 Hamap MF_00050 Elongation factor Ts [tsf]. 1 276 63.161 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 SUPERFAMILY SSF54713 65 141 7.03E-13 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 Gene3D G3DSA:1.10.286.20 194 240 4.3E-37 T 12-10-2018 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 274 4.6E-76 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFR_36215 305324ea2354c8093cc72fa8427d0dd8 276 Pfam PF00889 Elongation factor TS 68 275 1.7E-61 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 AFR_19980 4125d1634b8213791bf93d41d6d24cc4 597 SUPERFAMILY SSF50998 23 353 1.1E-11 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_19980 4125d1634b8213791bf93d41d6d24cc4 597 Gene3D G3DSA:2.60.120.200 388 595 1.1E-14 T 12-10-2018 AFR_19980 4125d1634b8213791bf93d41d6d24cc4 597 SUPERFAMILY SSF49899 383 594 2.24E-12 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_19980 4125d1634b8213791bf93d41d6d24cc4 597 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 475 594 1.8E-10 T 12-10-2018 AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 Pfam PF00005 ABC transporter 271 425 4.1E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 Gene3D G3DSA:3.40.50.300 259 492 3.6E-34 T 12-10-2018 AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 SUPERFAMILY SSF52540 271 484 7.65E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 SMART SM00382 278 481 8.4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 SMART SM00382 34 220 8.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 SUPERFAMILY SSF52540 9 224 6.95E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 Gene3D G3DSA:3.40.50.300 4 234 1.4E-48 T 12-10-2018 AFR_13075 d03bd13f50934af46b1d9e04ba8858fe 495 Pfam PF00005 ABC transporter 25 172 8.6E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_40370 1391a0e64ef0aeb512ee1f39e94e553e 273 SUPERFAMILY SSF51261 117 262 2.35E-34 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_40370 1391a0e64ef0aeb512ee1f39e94e553e 273 Gene3D G3DSA:2.70.70.10 121 270 1.6E-36 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_40370 1391a0e64ef0aeb512ee1f39e94e553e 273 Pfam PF01551 Peptidase family M23 148 250 8.4E-23 T 12-10-2018 IPR016047 Peptidase M23 AFR_40370 1391a0e64ef0aeb512ee1f39e94e553e 273 Gene3D G3DSA:2.30.30.40 37 109 1.3E-5 T 12-10-2018 AFR_06165 173b6c1f341b581f8c78546457a663e7 303 Pfam PF13732 Domain of unknown function (DUF4162) 215 300 4.4E-7 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 AFR_06165 173b6c1f341b581f8c78546457a663e7 303 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_06165 173b6c1f341b581f8c78546457a663e7 303 SUPERFAMILY SSF52540 4 223 9.71E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06165 173b6c1f341b581f8c78546457a663e7 303 SMART SM00382 27 210 5.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_06165 173b6c1f341b581f8c78546457a663e7 303 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 10 302 7.2E-101 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFR_06165 173b6c1f341b581f8c78546457a663e7 303 Gene3D G3DSA:3.40.50.300 1 232 2.5E-64 T 12-10-2018 AFR_06165 173b6c1f341b581f8c78546457a663e7 303 Pfam PF00005 ABC transporter 18 161 4.4E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 Pfam PF04539 Sigma-70 region 3 117 181 9.5E-8 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 244 2.5E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 Gene3D G3DSA:1.20.140.160 101 249 3.2E-35 T 12-10-2018 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 PIRSF PIRSF000770 3 267 1.2E-61 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 SUPERFAMILY SSF88659 166 247 3.36E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 SUPERFAMILY SSF88946 25 102 1.55E-19 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 SUPERFAMILY SSF88659 105 175 1.44E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 Gene3D G3DSA:1.10.1740.10 17 100 3.6E-22 T 12-10-2018 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 Pfam PF04545 Sigma-70, region 4 195 243 8.0E-10 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 30 246 3.6E-57 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFR_31860 16839c034ddfd7cff68b655a6bae4f70 305 Pfam PF04542 Sigma-70 region 2 30 102 6.6E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_15300 5bd30d907e5bb0021fa44cc7042cbc5f 273 Gene3D G3DSA:1.10.3720.10 2 261 1.3E-57 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15300 5bd30d907e5bb0021fa44cc7042cbc5f 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 265 9.7E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_15300 5bd30d907e5bb0021fa44cc7042cbc5f 273 SUPERFAMILY SSF161098 6 273 5.51E-63 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15405 99c4148851194c5fd0eb264855dd8dd2 237 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 233 3.2E-11 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_15405 99c4148851194c5fd0eb264855dd8dd2 237 SUPERFAMILY SSF56219 1 231 8.9E-26 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_15405 99c4148851194c5fd0eb264855dd8dd2 237 Gene3D G3DSA:3.60.10.10 1 236 4.1E-28 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_42340 1d6579f0be3bbaee50878f3365b0d620 292 Gene3D G3DSA:3.40.50.970 1 170 2.1E-41 T 12-10-2018 AFR_42340 1d6579f0be3bbaee50878f3365b0d620 292 Gene3D G3DSA:3.40.50.920 172 292 2.3E-7 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_42340 1d6579f0be3bbaee50878f3365b0d620 292 SUPERFAMILY SSF52518 2 160 2.46E-35 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_42340 1d6579f0be3bbaee50878f3365b0d620 292 SUPERFAMILY SSF52922 182 291 3.84E-9 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_42340 1d6579f0be3bbaee50878f3365b0d620 292 Pfam PF02779 Transketolase, pyrimidine binding domain 5 160 1.4E-23 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_42340 1d6579f0be3bbaee50878f3365b0d620 292 SMART SM00861 1 163 1.1E-18 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 Gene3D G3DSA:3.20.20.80 48 463 2.7E-149 T 12-10-2018 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 SMART SM00458 673 797 7.4E-30 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 Gene3D G3DSA:3.20.20.70 93 272 2.7E-149 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 SUPERFAMILY SSF49899 531 655 1.48E-7 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 540 659 1.8E-6 T 12-10-2018 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 Pfam PF00652 Ricin-type beta-trefoil lectin domain 676 794 7.9E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 SUPERFAMILY SSF50370 675 795 4.95E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 PRINTS PR00850 Glycosyl hydrolase family 59 signature 345 369 4.6E-10 T 12-10-2018 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 PRINTS PR00850 Glycosyl hydrolase family 59 signature 112 136 4.6E-10 T 12-10-2018 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 PRINTS PR00850 Glycosyl hydrolase family 59 signature 539 568 4.6E-10 T 12-10-2018 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 SUPERFAMILY SSF51445 51 354 2.63E-31 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 Pfam PF02057 Glycosyl hydrolase family 59 51 353 2.1E-76 T 12-10-2018 IPR001286 Glycoside hydrolase, family 59 GO:0004336|GO:0006683 KEGG: 00600+3.2.1.46|Reactome: R-HSA-1660662 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 Gene3D G3DSA:2.80.10.50 672 796 1.9E-40 T 12-10-2018 AFR_29160 d9ec854ab0ca76432420b857f33ed244 797 Gene3D G3DSA:2.60.120.560 472 667 2.4E-51 T 12-10-2018 AFR_34860 5aafe2dd1f04709f944902ea82f02409 253 SUPERFAMILY SSF53067 4 242 1.64E-16 T 12-10-2018 AFR_34860 5aafe2dd1f04709f944902ea82f02409 253 Gene3D G3DSA:3.30.420.40 119 250 2.1E-32 T 12-10-2018 AFR_34860 5aafe2dd1f04709f944902ea82f02409 253 Pfam PF00480 ROK family 5 152 9.3E-7 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_34860 5aafe2dd1f04709f944902ea82f02409 253 Gene3D G3DSA:3.30.420.40 2 118 1.0E-17 T 12-10-2018 AFR_09445 49455ce129d809b6b68343011de395e0 180 Pfam PF03551 Transcriptional regulator PadR-like family 13 83 1.6E-11 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_09445 49455ce129d809b6b68343011de395e0 180 Pfam PF10400 Virulence activator alpha C-term 95 170 5.3E-13 T 12-10-2018 IPR018309 Transcription regulator PadR, C-terminal AFR_09445 49455ce129d809b6b68343011de395e0 180 Gene3D G3DSA:1.10.10.10 9 90 1.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_09445 49455ce129d809b6b68343011de395e0 180 SUPERFAMILY SSF46785 12 173 5.55E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_28260 d65f14d63603179cde09f91052d40b12 674 Pfam PF00553 Cellulose binding domain 573 671 3.2E-18 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_28260 d65f14d63603179cde09f91052d40b12 674 Gene3D G3DSA:2.60.40.10 479 565 1.1E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_28260 d65f14d63603179cde09f91052d40b12 674 SMART SM00637 573 671 3.6E-25 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_28260 d65f14d63603179cde09f91052d40b12 674 Gene3D G3DSA:3.20.20.80 43 345 1.2E-66 T 12-10-2018 AFR_28260 d65f14d63603179cde09f91052d40b12 674 Gene3D G3DSA:2.60.40.290 566 674 1.2E-23 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_28260 d65f14d63603179cde09f91052d40b12 674 SUPERFAMILY SSF49265 474 567 1.07E-14 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_28260 d65f14d63603179cde09f91052d40b12 674 Pfam PF00041 Fibronectin type III domain 482 557 7.7E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_28260 d65f14d63603179cde09f91052d40b12 674 Gene3D G3DSA:2.60.40.1180 361 472 4.4E-13 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_28260 d65f14d63603179cde09f91052d40b12 674 SUPERFAMILY SSF51445 54 331 1.44E-45 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_28260 d65f14d63603179cde09f91052d40b12 674 SMART SM00060 480 554 5.6E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_28260 d65f14d63603179cde09f91052d40b12 674 SUPERFAMILY SSF49384 568 672 3.49E-22 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_22780 8a4fde97abe609c5299181209535d02b 263 Gene3D G3DSA:3.40.50.150 1 263 1.0E-113 T 12-10-2018 AFR_22780 8a4fde97abe609c5299181209535d02b 263 Pfam PF04672 S-adenosyl methyltransferase 3 263 1.0E-110 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_22780 8a4fde97abe609c5299181209535d02b 263 SUPERFAMILY SSF53335 9 248 4.17E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_22780 8a4fde97abe609c5299181209535d02b 263 PIRSF PIRSF017393 1 263 7.0E-104 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_32150 c45a229338f5853dd6dd35315461a166 1071 SMART SM01043 117 259 7.9E-28 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_32150 c45a229338f5853dd6dd35315461a166 1071 SUPERFAMILY SSF52540 272 545 1.25E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32150 c45a229338f5853dd6dd35315461a166 1071 SUPERFAMILY SSF46894 24 110 1.33E-8 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 Gene3D G3DSA:1.25.40.10 114 280 3.0E-33 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 Gene3D G3DSA:1.25.40.10 880 1067 1.5E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 Gene3D G3DSA:1.25.40.10 730 879 3.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 PRINTS PR00364 Disease resistance protein signature 481 495 2.5E-6 T 12-10-2018 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 PRINTS PR00364 Disease resistance protein signature 375 389 2.5E-6 T 12-10-2018 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 PRINTS PR00364 Disease resistance protein signature 300 315 2.5E-6 T 12-10-2018 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 SMART SM00862 37 110 0.0067 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 SUPERFAMILY SSF48452 112 272 7.59E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32150 c45a229338f5853dd6dd35315461a166 1071 Pfam PF03704 Bacterial transcriptional activator domain 117 259 3.6E-25 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_32150 c45a229338f5853dd6dd35315461a166 1071 Gene3D G3DSA:1.10.10.10 15 113 7.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33925 b046971e4f55baae3c95733e6c2e0f7a 138 SUPERFAMILY SSF51182 3 138 1.54E-43 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_33925 b046971e4f55baae3c95733e6c2e0f7a 138 Gene3D G3DSA:2.60.120.10 3 138 2.4E-42 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_33925 b046971e4f55baae3c95733e6c2e0f7a 138 Pfam PF06172 Cupin superfamily (DUF985) 8 137 1.1E-37 T 12-10-2018 IPR009327 Cupin domain of unknown function DUF985 AFR_05865 d2becefc51f1ca16ae602039b93a6879 223 Pfam PF00553 Cellulose binding domain 128 220 1.7E-14 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_05865 d2becefc51f1ca16ae602039b93a6879 223 Gene3D G3DSA:2.60.40.290 119 222 7.1E-20 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_05865 d2becefc51f1ca16ae602039b93a6879 223 SUPERFAMILY SSF49384 122 221 5.23E-16 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_05865 d2becefc51f1ca16ae602039b93a6879 223 SMART SM00637 126 220 5.3E-15 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 Pfam PF07729 FCD domain 89 224 2.3E-8 T 12-10-2018 IPR011711 GntR, C-terminal AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 SMART SM00345 21 79 4.8E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 SUPERFAMILY SSF48008 87 236 4.45E-8 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 SMART SM00895 89 230 0.0023 T 12-10-2018 IPR011711 GntR, C-terminal AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 Gene3D G3DSA:1.20.120.530 84 234 1.5E-13 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 74 3.8E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 SUPERFAMILY SSF46785 13 83 2.53E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_12705 3d3ed221f2db19b1197bb3f743f7bac7 239 Gene3D G3DSA:1.10.10.10 13 80 1.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10045 655eb53203997795bf48e9fe232e334a 273 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 6.4E-16 T 12-10-2018 IPR019933 DivIVA domain AFR_10045 655eb53203997795bf48e9fe232e334a 273 Pfam PF05103 DivIVA protein 3 55 1.5E-11 T 12-10-2018 IPR007793 DivIVA family AFR_34920 e29d3d3e8e51fc2e3cb2ad012e3aa9e4 383 Pfam PF00149 Calcineurin-like phosphoesterase 1 89 3.1E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_34920 e29d3d3e8e51fc2e3cb2ad012e3aa9e4 383 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 5.5E-52 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 AFR_34920 e29d3d3e8e51fc2e3cb2ad012e3aa9e4 383 SUPERFAMILY SSF56300 1 302 4.61E-52 T 12-10-2018 AFR_34920 e29d3d3e8e51fc2e3cb2ad012e3aa9e4 383 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 279 360 6.1E-6 T 12-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain AFR_34920 e29d3d3e8e51fc2e3cb2ad012e3aa9e4 383 Gene3D G3DSA:3.60.21.10 1 276 4.1E-72 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_18135 0029c142c99ef4d1df3ec7cd362dc2df 651 Pfam PF00082 Subtilase family 348 563 6.9E-12 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_18135 0029c142c99ef4d1df3ec7cd362dc2df 651 Pfam PF09286 Pro-kumamolisin, activation domain 51 181 8.4E-27 T 12-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 AFR_18135 0029c142c99ef4d1df3ec7cd362dc2df 651 Gene3D G3DSA:3.40.50.200 235 647 7.4E-82 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_18135 0029c142c99ef4d1df3ec7cd362dc2df 651 SUPERFAMILY SSF52743 246 642 8.77E-50 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_18135 0029c142c99ef4d1df3ec7cd362dc2df 651 SMART SM00944 48 193 1.9E-35 T 12-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 AFR_18135 0029c142c99ef4d1df3ec7cd362dc2df 651 SUPERFAMILY SSF54897 36 212 2.04E-34 T 12-10-2018 AFR_23530 afd112be984b4ac71ded32e892a47c72 138 SUPERFAMILY SSF54631 1 125 3.79E-33 T 12-10-2018 AFR_23530 afd112be984b4ac71ded32e892a47c72 138 SMART SM00116 77 124 3.4E-12 T 12-10-2018 IPR000644 CBS domain AFR_23530 afd112be984b4ac71ded32e892a47c72 138 SMART SM00116 11 59 1.5E-6 T 12-10-2018 IPR000644 CBS domain AFR_23530 afd112be984b4ac71ded32e892a47c72 138 Pfam PF00571 CBS domain 77 124 9.7E-12 T 12-10-2018 IPR000644 CBS domain AFR_23530 afd112be984b4ac71ded32e892a47c72 138 Pfam PF00571 CBS domain 4 55 4.7E-12 T 12-10-2018 IPR000644 CBS domain AFR_23530 afd112be984b4ac71ded32e892a47c72 138 Gene3D G3DSA:3.10.580.10 1 126 2.1E-42 T 12-10-2018 AFR_14890 a80ffb5bb8a5fd1ebe8cf182a21d261e 286 SUPERFAMILY SSF47413 29 81 2.96E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_14890 a80ffb5bb8a5fd1ebe8cf182a21d261e 286 Gene3D G3DSA:1.10.260.40 22 93 5.3E-8 T 12-10-2018 AFR_14890 a80ffb5bb8a5fd1ebe8cf182a21d261e 286 Pfam PF13560 Helix-turn-helix domain 7 85 5.2E-15 T 12-10-2018 AFR_14890 a80ffb5bb8a5fd1ebe8cf182a21d261e 286 SMART SM00530 10 82 9.8E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_41080 e0d9388de0cc0dc97d21c6ac2205c00e 142 Pfam PF00583 Acetyltransferase (GNAT) family 26 121 2.4E-18 T 12-10-2018 IPR000182 GNAT domain AFR_41080 e0d9388de0cc0dc97d21c6ac2205c00e 142 Gene3D G3DSA:3.40.630.30 2 129 6.0E-28 T 12-10-2018 AFR_41080 e0d9388de0cc0dc97d21c6ac2205c00e 142 SUPERFAMILY SSF55729 8 128 1.2E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 SUPERFAMILY SSF49384 462 559 3.42E-28 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 Gene3D G3DSA:3.20.20.80 38 412 5.7E-108 T 12-10-2018 AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 200 209 - T 12-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 SUPERFAMILY SSF51445 41 414 1.87E-76 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 Pfam PF00553 Cellulose binding domain 468 557 2.7E-25 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 SMART SM00637 468 560 3.1E-36 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 Gene3D G3DSA:2.60.40.290 465 563 7.6E-28 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_24740 8c00bb10b28a123acbbbbddbee6f48ef 563 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 52 386 8.2E-60 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AFR_36380 d49df9281606190a7e945a640cc7c331 618 Pfam PF17103 Stealth protein CR4, conserved region 4 509 557 8.4E-15 T 12-10-2018 IPR031356 Stealth protein CR4, conserved region 4 AFR_36380 d49df9281606190a7e945a640cc7c331 618 Pfam PF11380 Stealth protein CR2, conserved region 2 283 388 1.4E-44 T 12-10-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 AFR_36380 d49df9281606190a7e945a640cc7c331 618 Pfam PF17102 Stealth protein CR3, conserved region 3 433 481 4.6E-16 T 12-10-2018 IPR031357 Stealth protein CR3, conserved region 3 AFR_36380 d49df9281606190a7e945a640cc7c331 618 Pfam PF17101 Stealth protein CR1, conserved region 1 241 266 4.0E-14 T 12-10-2018 IPR031358 Stealth protein CR1, conserved region 1 AFR_30835 bd83512e7260d77feb42ed1c63fae56b 254 SUPERFAMILY SSF142823 11 248 1.31E-36 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 AFR_30835 bd83512e7260d77feb42ed1c63fae56b 254 Gene3D G3DSA:3.90.1560.10 22 252 2.2E-35 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 AFR_30835 bd83512e7260d77feb42ed1c63fae56b 254 Pfam PF04029 2-phosphosulpholactate phosphatase 30 245 4.2E-18 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 AFR_05590 bd24982d4a3723e0fd9b876f6b49af4d 161 SMART SM00347 19 119 1.6E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_05590 bd24982d4a3723e0fd9b876f6b49af4d 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 129 1.6E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_05590 bd24982d4a3723e0fd9b876f6b49af4d 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 43 59 1.6E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_05590 bd24982d4a3723e0fd9b876f6b49af4d 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 75 1.6E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_05590 bd24982d4a3723e0fd9b876f6b49af4d 161 Gene3D G3DSA:1.10.10.10 3 138 1.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05590 bd24982d4a3723e0fd9b876f6b49af4d 161 Pfam PF01047 MarR family 32 84 1.0E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_05590 bd24982d4a3723e0fd9b876f6b49af4d 161 SUPERFAMILY SSF46785 8 134 9.4E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 SUPERFAMILY SSF54368 5 102 5.89E-33 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 SMART SM01230 104 383 3.3E-153 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 473 6.8E-203 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 Gene3D G3DSA:3.30.590.10 107 462 1.7E-149 T 12-10-2018 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 390 402 - T 12-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 3.2E-133 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 96 4.0E-26 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 Gene3D G3DSA:3.10.20.70 4 106 7.9E-38 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09115 24277d709332a1a7021c7d5a05a96a9e 474 SUPERFAMILY SSF55931 105 473 7.75E-140 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_28845 638309cd875a16097cb1cdb068a53c28 234 Gene3D G3DSA:3.40.50.1820 1 232 8.0E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28845 638309cd875a16097cb1cdb068a53c28 234 SUPERFAMILY SSF53474 2 229 2.94E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28845 638309cd875a16097cb1cdb068a53c28 234 Pfam PF12697 Alpha/beta hydrolase family 5 223 3.1E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_08125 b9aa23c1246135e4e36ade16b4b8b9f7 194 Gene3D G3DSA:3.30.70.100 1 100 2.7E-16 T 12-10-2018 AFR_08125 b9aa23c1246135e4e36ade16b4b8b9f7 194 Pfam PF07978 NIPSNAP 3 98 1.6E-16 T 12-10-2018 IPR012577 NIPSNAP AFR_08125 b9aa23c1246135e4e36ade16b4b8b9f7 194 SUPERFAMILY SSF54909 1 98 1.11E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 Gene3D G3DSA:3.30.565.10 442 595 5.9E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 Pfam PF00512 His Kinase A (phospho-acceptor) domain 375 438 2.6E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 533 4.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 4.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 4.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 SMART SM00388 371 439 1.1E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 SUPERFAMILY SSF47384 362 438 3.34E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 SMART SM00387 480 592 7.4E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 SUPERFAMILY SSF55874 428 590 7.28E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 Gene3D G3DSA:3.30.450.350 83 271 1.5E-12 T 12-10-2018 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 SMART SM01079 78 269 7.9E-12 T 12-10-2018 IPR006189 CHASE domain AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 Gene3D G3DSA:1.10.287.130 332 437 2.6E-14 T 12-10-2018 AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 Pfam PF03924 CHASE domain 83 263 2.2E-24 T 12-10-2018 IPR006189 CHASE domain AFR_24115 ca81e28ef52ea767c43c5f9295e169a1 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 590 1.6E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_26190 3a4ece3dcf42477895ac4039f9b87ed6 280 Pfam PF08823 Putative peptidoglycan binding domain 209 275 4.1E-6 T 12-10-2018 IPR014927 Putative peptidoglycan binding AFR_26190 3a4ece3dcf42477895ac4039f9b87ed6 280 Pfam PF06267 Family of unknown function (DUF1028) 2 199 2.0E-67 T 12-10-2018 IPR010430 Protein of unknown function DUF1028 AFR_26190 3a4ece3dcf42477895ac4039f9b87ed6 280 SUPERFAMILY SSF56235 1 219 5.63E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_26190 3a4ece3dcf42477895ac4039f9b87ed6 280 Gene3D G3DSA:3.60.20.10 1 214 1.2E-68 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_42825 673b18fa74def7fd5e278b89cf49bdf7 188 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.076 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFR_42825 673b18fa74def7fd5e278b89cf49bdf7 188 Pfam PF00436 Single-strand binding protein family 6 106 1.7E-28 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFR_42825 673b18fa74def7fd5e278b89cf49bdf7 188 SUPERFAMILY SSF50249 6 188 8.0E-48 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_42825 673b18fa74def7fd5e278b89cf49bdf7 188 Gene3D G3DSA:2.40.50.140 1 120 6.3E-43 T 12-10-2018 AFR_42825 673b18fa74def7fd5e278b89cf49bdf7 188 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 188 5.6E-34 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFR_24675 9ce4f592d3d8ce6e84d8003f5d5c978e 266 SUPERFAMILY SSF53335 9 225 1.3E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_24675 9ce4f592d3d8ce6e84d8003f5d5c978e 266 Pfam PF08241 Methyltransferase domain 47 144 2.3E-19 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_24675 9ce4f592d3d8ce6e84d8003f5d5c978e 266 Gene3D G3DSA:3.40.50.150 28 214 2.3E-38 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 Gene3D G3DSA:3.30.565.10 1 217 1.3E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32030 46a2680db6bbb617905e76e7c5518356 656 ProSitePatterns PS00177 DNA topoisomerase II signature. 437 445 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 Pfam PF01751 Toprim domain 434 534 1.2E-13 T 12-10-2018 IPR006171 TOPRIM domain AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 254 272 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 607 619 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 325 341 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 389 409 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 188 201 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 173 188 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 623 639 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR01159 DNA gyrase subunit B signature 485 494 6.0E-27 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 Pfam PF00204 DNA gyrase B 215 405 2.9E-46 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 SUPERFAMILY SSF54211 262 405 2.47E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_32030 46a2680db6bbb617905e76e7c5518356 656 SUPERFAMILY SSF55874 1 203 3.01E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32030 46a2680db6bbb617905e76e7c5518356 656 SMART SM00433 10 647 2.1E-210 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 Gene3D G3DSA:3.40.50.670 414 656 6.3E-86 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 585 642 4.3E-23 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 SUPERFAMILY SSF56719 409 647 2.62E-75 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 Gene3D G3DSA:3.30.230.10 218 413 6.2E-44 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 45 58 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 501 517 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 88 102 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 10 25 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 519 536 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 539 551 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 280 293 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 435 449 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 PRINTS PR00418 DNA topoisomerase II family signature 586 602 3.2E-57 T 12-10-2018 AFR_32030 46a2680db6bbb617905e76e7c5518356 656 SMART SM00387 6 167 7.1E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_32030 46a2680db6bbb617905e76e7c5518356 656 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 6 111 3.8E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_00200 dceb953e303180ce94107480e156a8eb 829 Gene3D G3DSA:1.10.260.40 12 91 3.7E-12 T 12-10-2018 AFR_00200 dceb953e303180ce94107480e156a8eb 829 SMART SM00530 17 73 4.1E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_00200 dceb953e303180ce94107480e156a8eb 829 Gene3D G3DSA:3.40.50.300 94 233 4.9E-10 T 12-10-2018 AFR_00200 dceb953e303180ce94107480e156a8eb 829 Pfam PF13560 Helix-turn-helix domain 17 74 7.1E-11 T 12-10-2018 AFR_00200 dceb953e303180ce94107480e156a8eb 829 Gene3D G3DSA:1.25.40.10 521 819 1.3E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00200 dceb953e303180ce94107480e156a8eb 829 SUPERFAMILY SSF48452 539 712 1.11E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00200 dceb953e303180ce94107480e156a8eb 829 PRINTS PR00364 Disease resistance protein signature 189 203 7.3E-5 T 12-10-2018 AFR_00200 dceb953e303180ce94107480e156a8eb 829 PRINTS PR00364 Disease resistance protein signature 126 141 7.3E-5 T 12-10-2018 AFR_00200 dceb953e303180ce94107480e156a8eb 829 PRINTS PR00364 Disease resistance protein signature 296 310 7.3E-5 T 12-10-2018 AFR_00200 dceb953e303180ce94107480e156a8eb 829 SUPERFAMILY SSF52540 92 360 1.03E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00200 dceb953e303180ce94107480e156a8eb 829 SUPERFAMILY SSF47413 15 71 2.09E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_05870 fa84b81701840e8e66a6c82aeefebf96 239 SUPERFAMILY SSF54593 7 128 1.78E-12 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_05870 fa84b81701840e8e66a6c82aeefebf96 239 Gene3D G3DSA:3.10.180.10 1 135 4.0E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_12530 6026af5a7985488cba7c3762d4f0ef9b 244 SUPERFAMILY SSF46785 90 172 4.28E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_12530 6026af5a7985488cba7c3762d4f0ef9b 244 SUPERFAMILY SSF88659 5 43 4.36E-5 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_12530 6026af5a7985488cba7c3762d4f0ef9b 244 Pfam PF13936 Helix-turn-helix domain 5 45 5.2E-14 T 12-10-2018 IPR025246 Transposase IS30-like HTH domain AFR_12530 6026af5a7985488cba7c3762d4f0ef9b 244 Gene3D G3DSA:1.10.10.10 81 167 3.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12530 6026af5a7985488cba7c3762d4f0ef9b 244 Pfam PF12802 MarR family 103 161 9.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_13650 aeae8797c13cfc86cdd8b18981bd0e37 226 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 92 2.4E-15 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_13650 aeae8797c13cfc86cdd8b18981bd0e37 226 SUPERFAMILY SSF51735 4 197 1.43E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13650 aeae8797c13cfc86cdd8b18981bd0e37 226 Gene3D G3DSA:3.40.50.720 1 199 4.2E-49 T 12-10-2018 AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 SUPERFAMILY SSF100950 79 309 6.7E-35 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 Pfam PF13183 4Fe-4S dicluster domain 324 391 6.0E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 Pfam PF02589 LUD domain 86 294 4.9E-44 T 12-10-2018 IPR003741 LUD domain AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 Gene3D G3DSA:3.40.50.10420 157 295 3.5E-9 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 Pfam PF11870 Domain of unknown function (DUF3390) 403 472 3.1E-13 T 12-10-2018 IPR024569 4Fe-4S binding protein, C-terminal AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 SUPERFAMILY SSF54862 305 413 5.86E-14 T 12-10-2018 AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 33 458 7.8E-135 T 12-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 AFR_03290 bf9fe5be5b815e369af7af78bc4a3af6 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 327 338 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_23220 b55363384e344b1fc5d0ee7e1c7c9e9b 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 284 9.6E-74 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_23220 b55363384e344b1fc5d0ee7e1c7c9e9b 286 PIRSF PIRSF001359 1 285 1.1E-64 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_23220 b55363384e344b1fc5d0ee7e1c7c9e9b 286 Gene3D G3DSA:3.20.20.70 1 286 9.5E-77 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_23220 b55363384e344b1fc5d0ee7e1c7c9e9b 286 SUPERFAMILY SSF51569 3 284 2.05E-68 T 12-10-2018 AFR_04860 74531fcf32898a7a50e68ef376f492d2 142 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 11 138 1.8E-30 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 AFR_04860 74531fcf32898a7a50e68ef376f492d2 142 Pfam PF00583 Acetyltransferase (GNAT) family 25 114 5.5E-16 T 12-10-2018 IPR000182 GNAT domain AFR_04860 74531fcf32898a7a50e68ef376f492d2 142 Gene3D G3DSA:3.40.630.30 2 142 7.3E-37 T 12-10-2018 AFR_04860 74531fcf32898a7a50e68ef376f492d2 142 SUPERFAMILY SSF55729 1 129 9.29E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_13085 afb9507cf070188d3bdebcb799cd16c3 692 Pfam PF01968 Hydantoinase/oxoprolinase 206 493 9.9E-75 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFR_13085 afb9507cf070188d3bdebcb799cd16c3 692 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 1 185 1.7E-44 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFR_09380 ec3ee28f33a33ccf22483c10330a9043 70 SUPERFAMILY SSF64307 2 59 7.59E-18 T 12-10-2018 IPR036868 TusA-like domain superfamily AFR_09380 ec3ee28f33a33ccf22483c10330a9043 70 Gene3D G3DSA:3.30.110.40 2 69 7.4E-22 T 12-10-2018 IPR036868 TusA-like domain superfamily AFR_09380 ec3ee28f33a33ccf22483c10330a9043 70 Pfam PF01206 Sulfurtransferase TusA 2 58 1.0E-17 T 12-10-2018 IPR001455 TusA-like domain AFR_09380 ec3ee28f33a33ccf22483c10330a9043 70 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 4 28 - T 12-10-2018 IPR001455 TusA-like domain AFR_38945 f78d88137a447411d6f1d97165532b48 425 Gene3D G3DSA:3.40.50.12780 14 326 4.4E-65 T 12-10-2018 AFR_38945 f78d88137a447411d6f1d97165532b48 425 Pfam PF00501 AMP-binding enzyme 96 283 2.1E-5 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_38945 f78d88137a447411d6f1d97165532b48 425 SUPERFAMILY SSF56801 56 413 8.63E-26 T 12-10-2018 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 SUPERFAMILY SSF82866 142 331 5.89E-32 T 12-10-2018 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 SUPERFAMILY SSF82866 485 683 6.15E-27 T 12-10-2018 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 Gene3D G3DSA:1.20.1640.10 469 681 2.6E-5 T 12-10-2018 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 Pfam PF03176 MMPL family 472 683 2.1E-32 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 Pfam PF03176 MMPL family 45 361 1.7E-69 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 Gene3D G3DSA:1.20.1640.10 174 338 6.5E-10 T 12-10-2018 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 PRINTS PR00702 Acriflavin resistance protein family signature 174 197 3.0E-7 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 PRINTS PR00702 Acriflavin resistance protein family signature 227 251 3.0E-7 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_26025 ec8e32766585e7e50b47cdacb5d67cea 724 PRINTS PR00702 Acriflavin resistance protein family signature 302 325 3.0E-7 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 SUPERFAMILY SSF48498 104 241 1.22E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 98 240 6.9E-13 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 8.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 8.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 SUPERFAMILY SSF46689 31 91 1.44E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 Gene3D G3DSA:1.10.357.10 22 244 1.1E-55 T 12-10-2018 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 PRINTS PR00400 Tetracycline repressor protein signature 225 239 1.5E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 PRINTS PR00400 Tetracycline repressor protein signature 51 74 1.5E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 AFR_42045 f2f87e28d61d16cd863818a0d25c60c9 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 83 1.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 94 1.6E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 SUPERFAMILY SSF46894 3 94 3.12E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 PRINTS PR00364 Disease resistance protein signature 348 362 3.3E-7 T 12-10-2018 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 PRINTS PR00364 Disease resistance protein signature 278 293 3.3E-7 T 12-10-2018 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 PRINTS PR00364 Disease resistance protein signature 454 468 3.3E-7 T 12-10-2018 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 Gene3D G3DSA:1.10.10.10 1 96 4.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 Gene3D G3DSA:1.25.40.10 97 279 1.7E-41 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 SMART SM01043 99 233 1.1E-45 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 SMART SM00862 16 94 1.2E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 Pfam PF03704 Bacterial transcriptional activator domain 113 233 1.9E-35 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 SUPERFAMILY SSF48452 115 247 9.01E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 SUPERFAMILY SSF48452 777 928 6.35E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 Gene3D G3DSA:1.25.40.10 704 1014 3.3E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_17295 24fb6931d32a5a994cea0d78eae5c76e 1032 SUPERFAMILY SSF52540 247 520 2.08E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08835 967639cd2f27e8caede238cceccc0cff 153 Pfam PF00293 NUDIX domain 12 124 6.8E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_08835 967639cd2f27e8caede238cceccc0cff 153 Gene3D G3DSA:3.90.79.10 3 138 1.0E-25 T 12-10-2018 AFR_08835 967639cd2f27e8caede238cceccc0cff 153 PRINTS PR00502 NUDIX hydrolase family signature 38 52 1.6E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_08835 967639cd2f27e8caede238cceccc0cff 153 PRINTS PR00502 NUDIX hydrolase family signature 52 67 1.6E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_08835 967639cd2f27e8caede238cceccc0cff 153 SUPERFAMILY SSF55811 9 125 1.62E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_08835 967639cd2f27e8caede238cceccc0cff 153 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_00700 b6751079cb453cb718cb15cb351284aa 418 Pfam PF05977 Transmembrane secretion effector 2 392 8.2E-29 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_00700 b6751079cb453cb718cb15cb351284aa 418 Gene3D G3DSA:1.20.1250.20 12 392 5.4E-36 T 12-10-2018 AFR_00700 b6751079cb453cb718cb15cb351284aa 418 SUPERFAMILY SSF103473 12 392 2.88E-37 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_17385 1d7fc3f57257c525a4ee486c60898a60 153 Pfam PF04248 Domain of unknown function (DUF427) 20 111 1.5E-31 T 12-10-2018 IPR007361 Domain of unknown function DUF427 AFR_17385 1d7fc3f57257c525a4ee486c60898a60 153 Gene3D G3DSA:2.170.150.40 5 117 4.0E-34 T 12-10-2018 AFR_11950 c2bddb885cbfe9e3c70a3bc17bd6ba70 263 Gene3D G3DSA:3.40.50.1820 2 261 1.9E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11950 c2bddb885cbfe9e3c70a3bc17bd6ba70 263 SUPERFAMILY SSF53474 3 260 8.18E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11950 c2bddb885cbfe9e3c70a3bc17bd6ba70 263 Pfam PF12697 Alpha/beta hydrolase family 5 252 5.0E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 6 28 1.3E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 163 180 1.3E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 70 88 1.3E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 249 266 1.3E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 PRINTS PR01988 Putative bacilysin exporter bacE signature 136 157 1.3E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 SUPERFAMILY SSF103473 7 391 5.36E-37 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 Gene3D G3DSA:1.20.1250.20 3 389 1.9E-31 T 12-10-2018 AFR_41830 8de86a9286d79ef5d4bc8479a9ef98d2 400 Pfam PF05977 Transmembrane secretion effector 4 397 8.4E-26 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_02895 db609f4ef08ffcd6682940f1896f5415 146 SUPERFAMILY SSF46785 17 136 1.8E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_02895 db609f4ef08ffcd6682940f1896f5415 146 Pfam PF01047 MarR family 31 89 7.1E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02895 db609f4ef08ffcd6682940f1896f5415 146 Gene3D G3DSA:1.10.10.10 10 140 6.2E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02895 db609f4ef08ffcd6682940f1896f5415 146 SMART SM00347 24 124 1.2E-18 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_03535 65b6f8851e8e6d428ca6a8a15355c87c 267 Gene3D G3DSA:2.40.33.20 129 266 8.7E-7 T 12-10-2018 AFR_03535 65b6f8851e8e6d428ca6a8a15355c87c 267 SUPERFAMILY SSF50800 2 262 1.36E-15 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_03535 65b6f8851e8e6d428ca6a8a15355c87c 267 Pfam PF03476 MOSC N-terminal beta barrel domain 2 84 1.3E-9 T 12-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 AFR_03535 65b6f8851e8e6d428ca6a8a15355c87c 267 Pfam PF03473 MOSC domain 145 262 3.1E-13 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 AFR_16615 de8adba94b25878961cc7d4fb6c8cd26 547 Gene3D G3DSA:3.90.870.20 336 538 9.1E-74 T 12-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily AFR_16615 de8adba94b25878961cc7d4fb6c8cd26 547 SUPERFAMILY SSF55821 361 538 7.32E-9 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFR_16615 de8adba94b25878961cc7d4fb6c8cd26 547 Gene3D G3DSA:3.30.420.350 123 316 3.0E-82 T 12-10-2018 AFR_16615 de8adba94b25878961cc7d4fb6c8cd26 547 SUPERFAMILY SSF53067 1 326 6.21E-18 T 12-10-2018 AFR_16615 de8adba94b25878961cc7d4fb6c8cd26 547 Pfam PF16861 Carbamoyltransferase C-terminus 371 538 7.5E-64 T 12-10-2018 IPR031730 Carbamoyltransferase, C-terminal AFR_16615 de8adba94b25878961cc7d4fb6c8cd26 547 Gene3D G3DSA:3.30.420.40 10 323 3.0E-82 T 12-10-2018 AFR_16615 de8adba94b25878961cc7d4fb6c8cd26 547 Pfam PF02543 Carbamoyltransferase N-terminus 2 323 3.5E-55 T 12-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 AFR_26400 d2a1e06c2aa777ad3e9a1ecea1509cff 284 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 233 45.528 T 12-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 AFR_26400 d2a1e06c2aa777ad3e9a1ecea1509cff 284 Gene3D G3DSA:3.60.20.10 1 242 5.3E-61 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_26400 d2a1e06c2aa777ad3e9a1ecea1509cff 284 SUPERFAMILY SSF56235 10 229 1.08E-39 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_26400 d2a1e06c2aa777ad3e9a1ecea1509cff 284 Pfam PF00227 Proteasome subunit 25 190 2.4E-27 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFR_26400 d2a1e06c2aa777ad3e9a1ecea1509cff 284 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 229 2.5E-103 T 12-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 AFR_08425 b9d00fe1ea94327f9333d2efb95509f5 245 Pfam PF12867 DinB superfamily 90 233 3.3E-19 T 12-10-2018 IPR024775 DinB-like domain AFR_08425 b9d00fe1ea94327f9333d2efb95509f5 245 Gene3D G3DSA:1.20.120.450 64 236 5.7E-13 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_08425 b9d00fe1ea94327f9333d2efb95509f5 245 SUPERFAMILY SSF109854 82 232 4.58E-16 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_30185 0843bc8d3033ef4ce4bad87494c336d7 337 Pfam PF03466 LysR substrate binding domain 120 321 2.5E-25 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_30185 0843bc8d3033ef4ce4bad87494c336d7 337 SUPERFAMILY SSF53850 121 327 1.49E-24 T 12-10-2018 AFR_30185 0843bc8d3033ef4ce4bad87494c336d7 337 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 34 92 2.7E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_30185 0843bc8d3033ef4ce4bad87494c336d7 337 Gene3D G3DSA:3.40.190.10 124 322 4.0E-42 T 12-10-2018 AFR_30185 0843bc8d3033ef4ce4bad87494c336d7 337 Gene3D G3DSA:3.40.190.10 192 298 4.0E-42 T 12-10-2018 AFR_30185 0843bc8d3033ef4ce4bad87494c336d7 337 Gene3D G3DSA:1.10.10.10 27 115 8.9E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30185 0843bc8d3033ef4ce4bad87494c336d7 337 SUPERFAMILY SSF46785 33 115 1.47E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_07535 213759e667cadff68a90bae14be03e6c 449 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 418 9.9E-31 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 TIGRFAM TIGR00115 tig: trigger factor 12 416 1.1E-114 T 12-10-2018 IPR005215 Trigger factor GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 Gene3D G3DSA:3.10.50.40 151 243 1.4E-63 T 12-10-2018 AFR_07535 213759e667cadff68a90bae14be03e6c 449 SUPERFAMILY SSF102735 2 132 1.96E-35 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 SUPERFAMILY SSF54534 133 244 6.68E-19 T 12-10-2018 AFR_07535 213759e667cadff68a90bae14be03e6c 449 Gene3D G3DSA:3.30.70.1050 1 116 2.6E-31 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 PIRSF PIRSF003095 1 444 8.6E-112 T 12-10-2018 IPR005215 Trigger factor GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 Hamap MF_00303 Trigger factor [tig]. 1 426 18.733 T 12-10-2018 IPR005215 Trigger factor GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 Pfam PF05697 Bacterial trigger factor protein (TF) 2 143 4.2E-39 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 Gene3D G3DSA:1.10.3120.10 117 422 1.4E-63 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 AFR_07535 213759e667cadff68a90bae14be03e6c 449 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 215 4.6E-5 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFR_07535 213759e667cadff68a90bae14be03e6c 449 SUPERFAMILY SSF109998 245 430 6.28E-35 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily AFR_19745 9b8821e5c8248451fb61c3f00246fff0 327 SUPERFAMILY SSF50129 6 155 1.48E-15 T 12-10-2018 IPR011032 GroES-like superfamily AFR_19745 9b8821e5c8248451fb61c3f00246fff0 327 SUPERFAMILY SSF51735 121 257 4.75E-15 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19745 9b8821e5c8248451fb61c3f00246fff0 327 Gene3D G3DSA:3.40.50.720 133 259 2.3E-18 T 12-10-2018 AFR_19745 9b8821e5c8248451fb61c3f00246fff0 327 Gene3D G3DSA:3.90.180.10 104 305 2.3E-18 T 12-10-2018 AFR_19745 9b8821e5c8248451fb61c3f00246fff0 327 Gene3D G3DSA:3.90.180.10 2 96 1.7E-6 T 12-10-2018 AFR_22285 ceabbd11e003c8bbde021c4f8b97fefb 310 SUPERFAMILY SSF55729 19 304 1.73E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_22285 ceabbd11e003c8bbde021c4f8b97fefb 310 Gene3D G3DSA:3.40.630.30 6 309 2.9E-19 T 12-10-2018 AFR_15980 3d73956c10b1bb1680fd1a707f5f25be 354 Gene3D G3DSA:3.40.50.2000 199 353 1.8E-11 T 12-10-2018 AFR_15980 3d73956c10b1bb1680fd1a707f5f25be 354 SUPERFAMILY SSF53756 53 331 3.77E-13 T 12-10-2018 AFR_19555 8fe2dae3646180d767562e89d24c03dc 315 SUPERFAMILY SSF52540 1 238 1.93E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19555 8fe2dae3646180d767562e89d24c03dc 315 Gene3D G3DSA:3.40.50.300 1 262 4.5E-36 T 12-10-2018 AFR_19555 8fe2dae3646180d767562e89d24c03dc 315 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 94 1.9E-9 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFR_10305 728b2a57d20b703f6a21dba055ad6f06 267 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 49 66 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 AFR_10305 728b2a57d20b703f6a21dba055ad6f06 267 Gene3D G3DSA:3.20.20.70 1 267 1.0E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10305 728b2a57d20b703f6a21dba055ad6f06 267 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 255 32.453 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFR_10305 728b2a57d20b703f6a21dba055ad6f06 267 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 29 251 30.464 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFR_10305 728b2a57d20b703f6a21dba055ad6f06 267 Pfam PF00218 Indole-3-glycerol phosphate synthase 2 253 1.1E-81 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFR_10305 728b2a57d20b703f6a21dba055ad6f06 267 SUPERFAMILY SSF51366 10 255 5.27E-81 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_08800 9f6ebbade3cb333db6e02b236cab38d3 154 PIRSF PIRSF000239 1 143 1.3E-26 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_08800 9f6ebbade3cb333db6e02b236cab38d3 154 Pfam PF00578 AhpC/TSA family 5 130 6.7E-39 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_08800 9f6ebbade3cb333db6e02b236cab38d3 154 Gene3D G3DSA:3.40.30.10 1 153 8.1E-51 T 12-10-2018 AFR_08800 9f6ebbade3cb333db6e02b236cab38d3 154 SUPERFAMILY SSF52833 1 150 8.2E-46 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_10010 758b56247de60f82dddc71cab550b61c 369 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 5 361 3.7E-82 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10010 758b56247de60f82dddc71cab550b61c 369 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 146 4.8E-34 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10010 758b56247de60f82dddc71cab550b61c 369 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 366 30.676 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10010 758b56247de60f82dddc71cab550b61c 369 Gene3D G3DSA:3.40.50.2000 169 350 6.8E-95 T 12-10-2018 AFR_10010 758b56247de60f82dddc71cab550b61c 369 Gene3D G3DSA:3.40.50.2000 8 354 6.8E-95 T 12-10-2018 AFR_10010 758b56247de60f82dddc71cab550b61c 369 SUPERFAMILY SSF53756 6 365 2.39E-94 T 12-10-2018 AFR_10010 758b56247de60f82dddc71cab550b61c 369 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 197 349 2.2E-33 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AFR_20315 7fa2bed0c33e60dc0d67255d3e5d2230 222 Pfam PF00072 Response regulator receiver domain 4 112 7.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20315 7fa2bed0c33e60dc0d67255d3e5d2230 222 Gene3D G3DSA:3.40.50.2300 1 120 4.3E-37 T 12-10-2018 AFR_20315 7fa2bed0c33e60dc0d67255d3e5d2230 222 SMART SM00862 145 216 2.0E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_20315 7fa2bed0c33e60dc0d67255d3e5d2230 222 SUPERFAMILY SSF52172 2 179 1.46E-38 T 12-10-2018 IPR011006 CheY-like superfamily AFR_20315 7fa2bed0c33e60dc0d67255d3e5d2230 222 Gene3D G3DSA:1.10.10.10 123 220 2.2E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20315 7fa2bed0c33e60dc0d67255d3e5d2230 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 216 7.1E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_20315 7fa2bed0c33e60dc0d67255d3e5d2230 222 SMART SM00448 1 112 5.1E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21845 4cf6c3327dfacd4ba172c2a70a860f52 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 3.8E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_21845 4cf6c3327dfacd4ba172c2a70a860f52 225 Pfam PF00072 Response regulator receiver domain 4 113 4.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21845 4cf6c3327dfacd4ba172c2a70a860f52 225 SMART SM00448 2 112 1.3E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21845 4cf6c3327dfacd4ba172c2a70a860f52 225 Gene3D G3DSA:3.40.50.2300 1 122 1.5E-35 T 12-10-2018 AFR_21845 4cf6c3327dfacd4ba172c2a70a860f52 225 Gene3D G3DSA:1.10.10.10 123 225 8.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21845 4cf6c3327dfacd4ba172c2a70a860f52 225 SMART SM00862 147 223 2.6E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_21845 4cf6c3327dfacd4ba172c2a70a860f52 225 SUPERFAMILY SSF52172 3 182 8.97E-40 T 12-10-2018 IPR011006 CheY-like superfamily AFR_26975 1a6be853c57077243495461ae9e40596 267 Gene3D G3DSA:3.60.10.10 1 254 1.7E-70 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_26975 1a6be853c57077243495461ae9e40596 267 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 12-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 AFR_26975 1a6be853c57077243495461ae9e40596 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 252 4.6E-75 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AFR_26975 1a6be853c57077243495461ae9e40596 267 SUPERFAMILY SSF56219 1 252 5.89E-71 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_26975 1a6be853c57077243495461ae9e40596 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 5.7E-24 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_26975 1a6be853c57077243495461ae9e40596 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 251 2.8E-61 T 12-10-2018 AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Pfam PF10566 Glycoside hydrolase 97 275 505 1.2E-63 T 12-10-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 36 270 2.8E-33 T 12-10-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 507 596 5.0E-17 T 12-10-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Gene3D G3DSA:2.60.120.1060 733 878 1.7E-42 T 12-10-2018 IPR038637 NPCBM domain superfamily AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 SUPERFAMILY SSF49785 740 880 1.91E-38 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 SUPERFAMILY SSF51445 275 474 4.21E-18 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Gene3D G3DSA:2.60.40.1180 508 596 1.1E-17 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Gene3D G3DSA:3.20.20.70 270 507 6.9E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 SMART SM00776 734 879 7.5E-59 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Pfam PF08305 NPCBM/NEW2 domain 738 877 2.2E-46 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 627 701 1.2E-7 T 12-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain AFR_31770 f559630c3205833bfb2e5b75ba1f19d0 881 Gene3D G3DSA:2.70.98.10 32 259 1.5E-22 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_16550 ae0aa866a8bd3c1c94e51c6bc302771b 173 SUPERFAMILY SSF51182 9 154 1.87E-26 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_16550 ae0aa866a8bd3c1c94e51c6bc302771b 173 Gene3D G3DSA:2.60.120.10 15 149 1.1E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_16550 ae0aa866a8bd3c1c94e51c6bc302771b 173 Pfam PF05995 Cysteine dioxygenase type I 25 146 1.7E-15 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 AFR_12865 3c3f87cb3a05d36330338f383281cf76 115 SUPERFAMILY SSF46785 6 98 4.87E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_12865 3c3f87cb3a05d36330338f383281cf76 115 Gene3D G3DSA:1.10.10.10 3 100 2.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12865 3c3f87cb3a05d36330338f383281cf76 115 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 1.3E-19 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_22210 07b9eee4f1f25c443b58d648dbd2d59f 157 Gene3D G3DSA:3.90.280.10 2 153 7.2E-32 T 12-10-2018 IPR036610 PEBP-like superfamily AFR_22210 07b9eee4f1f25c443b58d648dbd2d59f 157 Pfam PF01161 Phosphatidylethanolamine-binding protein 34 151 1.1E-19 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein AFR_22210 07b9eee4f1f25c443b58d648dbd2d59f 157 SUPERFAMILY SSF49777 14 151 6.41E-32 T 12-10-2018 IPR036610 PEBP-like superfamily AFR_06945 55a44e07b9c74371a4cabedaf53ab5fb 139 Pfam PF04075 F420H(2)-dependent quinone reductase 18 133 1.4E-31 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_06945 55a44e07b9c74371a4cabedaf53ab5fb 139 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 26 135 2.7E-31 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_06945 55a44e07b9c74371a4cabedaf53ab5fb 139 Gene3D G3DSA:2.30.110.10 2 137 3.5E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_06945 55a44e07b9c74371a4cabedaf53ab5fb 139 SUPERFAMILY SSF50475 27 134 8.48E-14 T 12-10-2018 AFR_25320 f99b6c7981e4bd44f022a06e8c560e5c 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 2.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_25320 f99b6c7981e4bd44f022a06e8c560e5c 193 Gene3D G3DSA:1.10.10.60 2 53 1.5E-18 T 12-10-2018 AFR_25320 f99b6c7981e4bd44f022a06e8c560e5c 193 SUPERFAMILY SSF48498 74 190 3.11E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_25320 f99b6c7981e4bd44f022a06e8c560e5c 193 SUPERFAMILY SSF46689 4 70 4.51E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_25320 f99b6c7981e4bd44f022a06e8c560e5c 193 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 184 1.6E-21 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_25320 f99b6c7981e4bd44f022a06e8c560e5c 193 Gene3D G3DSA:1.10.357.10 54 192 8.2E-20 T 12-10-2018 AFR_11425 8823ea5aee9c25c05bd17fe31e7537b6 153 Gene3D G3DSA:3.30.70.3040 25 133 6.0E-12 T 12-10-2018 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Gene3D G3DSA:3.30.420.40 349 360 1.4E-21 T 12-10-2018 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Pfam PF00480 ROK family 86 246 9.6E-28 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Pfam PF00480 ROK family 277 364 1.5E-9 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Gene3D G3DSA:3.30.420.40 208 245 3.0E-38 T 12-10-2018 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Gene3D G3DSA:1.10.10.10 2 77 6.3E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Gene3D G3DSA:3.30.420.40 273 348 1.4E-21 T 12-10-2018 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Gene3D G3DSA:3.30.420.40 91 207 3.0E-38 T 12-10-2018 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 Pfam PF09339 IclR helix-turn-helix domain 16 58 3.2E-5 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 SUPERFAMILY SSF53067 83 370 8.65E-46 T 12-10-2018 AFR_14940 5d64ceb3ce2ca0a00fc525570df058f2 386 SUPERFAMILY SSF46785 12 77 1.48E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 4.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 4.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 4.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 4.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 SUPERFAMILY SSF46785 39 144 5.97E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 Pfam PF12802 MarR family 39 94 8.9E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 Gene3D G3DSA:1.10.10.10 10 146 1.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06045 db5e70cd29f6ee76d14b94130b89844e 149 SMART SM00347 39 130 9.3E-18 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32160 82e583594a99644e71154b7a4c9c582c 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 2.3E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32160 82e583594a99644e71154b7a4c9c582c 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32160 82e583594a99644e71154b7a4c9c582c 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32160 82e583594a99644e71154b7a4c9c582c 192 Gene3D G3DSA:1.10.10.60 5 62 2.5E-21 T 12-10-2018 AFR_32160 82e583594a99644e71154b7a4c9c582c 192 SUPERFAMILY SSF46689 4 69 8.21E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_32160 82e583594a99644e71154b7a4c9c582c 192 Gene3D G3DSA:1.10.357.10 63 182 4.8E-17 T 12-10-2018 AFR_32160 82e583594a99644e71154b7a4c9c582c 192 SUPERFAMILY SSF48498 78 179 2.15E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_37705 f2356f1cca1c7da6fd5f1e4c3d523d88 158 Pfam PF00583 Acetyltransferase (GNAT) family 50 134 2.9E-11 T 12-10-2018 IPR000182 GNAT domain AFR_37705 f2356f1cca1c7da6fd5f1e4c3d523d88 158 Gene3D G3DSA:3.40.630.30 1 143 4.6E-24 T 12-10-2018 AFR_37705 f2356f1cca1c7da6fd5f1e4c3d523d88 158 SUPERFAMILY SSF55729 5 145 9.12E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 SUPERFAMILY SSF49303 430 514 1.12E-14 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Gene3D G3DSA:3.90.182.10 7 144 7.9E-18 T 12-10-2018 AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 301 387 3.2E-14 T 12-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 SMART SM00560 873 1005 2.2E-13 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Gene3D G3DSA:2.60.120.200 814 1014 2.8E-43 T 12-10-2018 AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Pfam PF00703 Glycosyl hydrolases family 2 428 513 2.5E-10 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Pfam PF07691 PA14 domain 37 121 5.4E-19 T 12-10-2018 IPR011658 PA14 domain AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 SMART SM00758 2 132 3.1E-19 T 12-10-2018 IPR011658 PA14 domain AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 SUPERFAMILY SSF51445 510 792 1.05E-52 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 SUPERFAMILY SSF56988 17 138 6.02E-30 T 12-10-2018 AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 SUPERFAMILY SSF49785 256 423 6.52E-43 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Gene3D G3DSA:3.20.20.80 524 793 2.3E-42 T 12-10-2018 AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 SUPERFAMILY SSF49899 815 1013 3.6E-40 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Gene3D G3DSA:2.60.120.260 261 423 8.3E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Gene3D G3DSA:2.60.40.10 426 514 1.5E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_15140 b5ad777ebdce83fb852e6c11268e5179 1016 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 856 1008 5.2E-29 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Gene3D G3DSA:3.50.50.60 114 244 1.9E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 SUPERFAMILY SSF51905 3 197 1.83E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 4 796 2.9E-251 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 631 766 1.3E-21 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Gene3D G3DSA:3.30.390.30 324 401 9.5E-7 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00397 Sirohaem Fe-binding site signature 678 696 5.0E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00397 Sirohaem Fe-binding site signature 635 653 5.0E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 678 694 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Gene3D G3DSA:3.90.480.10 544 629 2.8E-7 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 3.2E-10 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 3.2E-10 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.2E-10 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 3.2E-10 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Gene3D G3DSA:3.30.413.10 630 792 1.6E-34 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 SUPERFAMILY SSF56014 633 798 1.83E-47 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 1.1E-16 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.1E-16 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.1E-16 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.1E-16 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 1.1E-16 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Gene3D G3DSA:3.50.50.60 5 302 1.9E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 287 2.0E-54 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 561 623 5.6E-15 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 PIRSF PIRSF037149 1 822 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 SUPERFAMILY SSF51905 148 312 2.83E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 SUPERFAMILY SSF55124 523 640 2.04E-22 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Gene3D G3DSA:1.10.10.1100 423 474 7.1E-10 T 12-10-2018 AFR_18685 2c6307f51e3e5bacd174fb39ea201e91 825 Pfam PF04324 BFD-like [2Fe-2S] binding domain 424 471 5.8E-12 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain AFR_30980 ea668bd91f2f32609d70606138164b4d 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 219 241 2.1E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFR_30980 ea668bd91f2f32609d70606138164b4d 252 SUPERFAMILY SSF52540 4 242 9.53E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30980 ea668bd91f2f32609d70606138164b4d 252 Pfam PF00005 ABC transporter 21 172 2.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_30980 ea668bd91f2f32609d70606138164b4d 252 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 4 242 9.8E-103 T 12-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD AFR_30980 ea668bd91f2f32609d70606138164b4d 252 Gene3D G3DSA:3.40.50.300 1 243 3.3E-57 T 12-10-2018 AFR_32675 7624216054615dfa0fba4718ccb324a1 168 Pfam PF09348 Domain of unknown function (DUF1990) 5 155 3.7E-49 T 12-10-2018 IPR018960 Domain of unknown function DUF1990 AFR_32675 7624216054615dfa0fba4718ccb324a1 168 PIRSF PIRSF010260 1 162 4.1E-48 T 12-10-2018 IPR014457 Uncharacterised conserved protein UCP010260 AFR_09110 522a21a786751ceec7bc1c294df4ac24 141 Pfam PF06271 RDD family 25 130 9.1E-8 T 12-10-2018 IPR010432 RDD AFR_04435 d9684694824ac47eefdbf317e7e9651e 244 Pfam PF00005 ABC transporter 19 146 3.6E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04435 d9684694824ac47eefdbf317e7e9651e 244 SUPERFAMILY SSF52540 2 188 1.57E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04435 d9684694824ac47eefdbf317e7e9651e 244 SMART SM00382 27 240 4.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_04435 d9684694824ac47eefdbf317e7e9651e 244 Gene3D G3DSA:3.40.50.300 1 223 7.5E-39 T 12-10-2018 AFR_00925 90af2172fecc39249455f37c0dc299a0 285 Gene3D G3DSA:3.30.750.24 189 280 2.4E-10 T 12-10-2018 IPR036513 STAS domain superfamily AFR_00925 90af2172fecc39249455f37c0dc299a0 285 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 14 169 1.3E-36 T 12-10-2018 IPR025847 MEDS domain AFR_00925 90af2172fecc39249455f37c0dc299a0 285 SUPERFAMILY SSF52091 194 271 1.73E-7 T 12-10-2018 IPR036513 STAS domain superfamily AFR_00925 90af2172fecc39249455f37c0dc299a0 285 Pfam PF13466 STAS domain 194 260 1.8E-8 T 12-10-2018 IPR002645 STAS domain AFR_07290 99fd24b55c0433da085c126f7594bb79 510 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 261 439 1.1E-44 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFR_07290 99fd24b55c0433da085c126f7594bb79 510 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 235 7.0E-19 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFR_07290 99fd24b55c0433da085c126f7594bb79 510 SUPERFAMILY SSF52540 1 243 1.74E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07290 99fd24b55c0433da085c126f7594bb79 510 Gene3D G3DSA:3.40.50.880 260 437 1.5E-24 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_07290 99fd24b55c0433da085c126f7594bb79 510 SUPERFAMILY SSF52317 262 445 3.75E-36 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_07290 99fd24b55c0433da085c126f7594bb79 510 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 487 3.6E-133 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AFR_07290 99fd24b55c0433da085c126f7594bb79 510 Gene3D G3DSA:3.40.50.300 5 244 1.1E-49 T 12-10-2018 AFR_07290 99fd24b55c0433da085c126f7594bb79 510 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 496 176.583 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AFR_17350 74cd977a1af220671b708d47767c99c1 378 Pfam PF13439 Glycosyltransferase Family 4 18 127 1.2E-13 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_17350 74cd977a1af220671b708d47767c99c1 378 Gene3D G3DSA:3.40.50.2000 10 367 5.9E-64 T 12-10-2018 AFR_17350 74cd977a1af220671b708d47767c99c1 378 Gene3D G3DSA:3.40.50.2000 169 361 5.9E-64 T 12-10-2018 AFR_17350 74cd977a1af220671b708d47767c99c1 378 Pfam PF00534 Glycosyl transferases group 1 186 350 6.0E-16 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_17350 74cd977a1af220671b708d47767c99c1 378 SUPERFAMILY SSF53756 13 367 4.31E-43 T 12-10-2018 AFR_23925 08f809b4d52f40bba848ff901c9fb27a 379 SUPERFAMILY SSF88946 4 84 9.42E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23925 08f809b4d52f40bba848ff901c9fb27a 379 Pfam PF04542 Sigma-70 region 2 6 68 1.4E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23925 08f809b4d52f40bba848ff901c9fb27a 379 Pfam PF08281 Sigma-70, region 4 98 148 1.2E-7 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_23925 08f809b4d52f40bba848ff901c9fb27a 379 Gene3D G3DSA:1.10.10.10 67 152 4.1E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23925 08f809b4d52f40bba848ff901c9fb27a 379 SUPERFAMILY SSF88659 92 149 2.83E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_34925 23a1c7cbf4049214bc816b54ee7e114a 576 SUPERFAMILY SSF52540 100 533 1.28E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34925 23a1c7cbf4049214bc816b54ee7e114a 576 Gene3D G3DSA:3.40.50.300 309 540 9.7E-14 T 12-10-2018 AFR_09165 dd84a10d616b42411c03df28f039230b 107 Gene3D G3DSA:3.30.70.120 1 107 2.4E-38 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFR_09165 dd84a10d616b42411c03df28f039230b 107 SUPERFAMILY SSF54913 2 105 1.59E-36 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFR_09165 dd84a10d616b42411c03df28f039230b 107 Pfam PF03091 CutA1 divalent ion tolerance protein 6 103 5.5E-36 T 12-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 SUPERFAMILY SSF88946 6 86 1.49E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 SUPERFAMILY SSF54427 166 278 3.32E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 154 5.1E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 Gene3D G3DSA:3.10.450.50 164 280 1.2E-7 T 12-10-2018 AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 6 281 1.6E-107 T 12-10-2018 IPR014303 RNA polymerase sigma-70, ECF type AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 Gene3D G3DSA:1.10.1740.10 2 73 2.3E-9 T 12-10-2018 AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 Pfam PF08281 Sigma-70, region 4 103 153 1.1E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 SUPERFAMILY SSF88659 70 157 1.1E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 Pfam PF04542 Sigma-70 region 2 8 70 3.1E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_07250 f9ca8830144af0d7864a267b6f78c5c5 289 Gene3D G3DSA:1.10.10.10 86 158 2.8E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35160 fc7228ffcee5bfe5b30434cdd86b8557 143 Gene3D G3DSA:3.40.630.30 3 143 4.2E-37 T 12-10-2018 AFR_35160 fc7228ffcee5bfe5b30434cdd86b8557 143 SUPERFAMILY SSF55729 5 142 9.73E-31 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35160 fc7228ffcee5bfe5b30434cdd86b8557 143 Pfam PF13673 Acetyltransferase (GNAT) domain 47 142 8.6E-15 T 12-10-2018 IPR000182 GNAT domain AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 SMART SM00014 353 465 2.3E-9 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 SMART SM00014 108 221 4.0E-18 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 SUPERFAMILY SSF48317 271 473 7.59E-29 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 SUPERFAMILY SSF48317 30 230 3.66E-35 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 Gene3D G3DSA:1.20.144.10 386 492 3.4E-18 T 12-10-2018 AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 Gene3D G3DSA:1.20.144.10 25 140 1.3E-6 T 12-10-2018 AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 Gene3D G3DSA:1.20.144.10 141 240 2.8E-20 T 12-10-2018 AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 Pfam PF01569 PAP2 superfamily 111 224 2.3E-17 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_32655 97d5893d96e51022c6baa5a3a2e3556d 500 Pfam PF01569 PAP2 superfamily 368 469 3.0E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_04500 80305871b3e715174647b9716cf59e95 102 Gene3D G3DSA:3.30.70.600 1 102 6.3E-39 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AFR_04500 80305871b3e715174647b9716cf59e95 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04500 80305871b3e715174647b9716cf59e95 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04500 80305871b3e715174647b9716cf59e95 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.3E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04500 80305871b3e715174647b9716cf59e95 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 3.5E-37 T 12-10-2018 IPR027486 Ribosomal protein S10 domain AFR_04500 80305871b3e715174647b9716cf59e95 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04500 80305871b3e715174647b9716cf59e95 102 SMART SM01403 7 101 8.3E-60 T 12-10-2018 IPR027486 Ribosomal protein S10 domain AFR_04500 80305871b3e715174647b9716cf59e95 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04500 80305871b3e715174647b9716cf59e95 102 SUPERFAMILY SSF54999 5 102 2.22E-39 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AFR_04500 80305871b3e715174647b9716cf59e95 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.0E-48 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 SMART SM00448 2 113 1.0E-47 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 SUPERFAMILY SSF52172 4 122 2.42E-45 T 12-10-2018 IPR011006 CheY-like superfamily AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 Gene3D G3DSA:3.40.50.2300 3 125 4.6E-42 T 12-10-2018 AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 SMART SM00862 150 225 7.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 SUPERFAMILY SSF46894 127 225 6.24E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 Pfam PF00072 Response regulator receiver domain 5 113 1.8E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 Gene3D G3DSA:1.10.10.10 126 226 1.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23465 2e5df7f0a37abda261b08ed295b634de 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 1.8E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Gene3D G3DSA:3.40.50.300 345 548 1.2E-67 T 12-10-2018 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 SUPERFAMILY SSF81923 4 157 4.91E-30 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 3.3E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 3.3E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 3.3E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 3.3E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 SUPERFAMILY SSF52540 159 549 2.2E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Gene3D G3DSA:3.40.50.300 151 344 1.8E-72 T 12-10-2018 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 SMART SM00382 200 346 2.4E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 SMART SM00382 601 755 6.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 318 6.6E-11 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 762 3.4E-53 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Gene3D G3DSA:1.10.1780.10 1 150 3.9E-30 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 4.5E-25 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 2.1E-9 T 12-10-2018 IPR004176 Clp, N-terminal AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 21 66 3.3E-9 T 12-10-2018 IPR004176 Clp, N-terminal AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Gene3D G3DSA:3.40.50.300 554 767 1.3E-83 T 12-10-2018 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 SUPERFAMILY SSF52540 550 852 3.72E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 Gene3D G3DSA:1.10.8.60 768 862 1.1E-27 T 12-10-2018 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 854 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 AFR_00565 cdc2be71e8137c1d18ab070a0e809e28 862 SMART SM01086 768 859 3.0E-35 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 Gene3D G3DSA:3.30.420.40 7 324 1.3E-113 T 12-10-2018 AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 Gene3D G3DSA:3.30.420.40 132 304 1.3E-113 T 12-10-2018 AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 Pfam PF00814 Glycoprotease family 27 317 5.7E-93 T 12-10-2018 IPR000905 Gcp-like domain AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 2.7E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 274 283 2.7E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 2.7E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 2.7E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.7E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.7E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 323 5.2E-124 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 317 3.0E-96 T 12-10-2018 IPR017861 Kae1/TsaD family AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 343 61.995 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 AFR_04865 70c7b56985defb2458252ddb03d25d4c 350 SUPERFAMILY SSF53067 6 319 5.83E-37 T 12-10-2018 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 335 361 3.7E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 150 163 3.7E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 174 202 3.7E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 226 243 3.7E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 244 260 3.7E-45 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 196 494 1.9E-113 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 SUPERFAMILY SSF55347 184 495 1.47E-110 T 12-10-2018 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 19 194 1.6E-48 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 Gene3D G3DSA:3.30.360.10 184 482 3.1E-171 T 12-10-2018 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 16 495 3.0E-182 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 Gene3D G3DSA:3.40.50.720 18 443 3.1E-171 T 12-10-2018 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 15 495 81.269 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_25430 105c5114fd9edbd532068375c0306a0c 497 SUPERFAMILY SSF51735 10 197 1.5E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_25430 105c5114fd9edbd532068375c0306a0c 497 PIRSF PIRSF000110 5 497 5.3E-168 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_00575 9e99e5b41f306d3a050bcd9091cefee1 301 PRINTS PR01217 Proline rich extensin signature 223 239 9.1E-9 T 12-10-2018 AFR_00575 9e99e5b41f306d3a050bcd9091cefee1 301 PRINTS PR01217 Proline rich extensin signature 241 258 9.1E-9 T 12-10-2018 AFR_00575 9e99e5b41f306d3a050bcd9091cefee1 301 PRINTS PR01217 Proline rich extensin signature 199 220 9.1E-9 T 12-10-2018 AFR_00575 9e99e5b41f306d3a050bcd9091cefee1 301 PRINTS PR01217 Proline rich extensin signature 275 300 9.1E-9 T 12-10-2018 AFR_09720 8d23af357333a2890a04fb6d481b68eb 355 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 89 103 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFR_09720 8d23af357333a2890a04fb6d481b68eb 355 SUPERFAMILY SSF48576 19 354 3.5E-75 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_09720 8d23af357333a2890a04fb6d481b68eb 355 Gene3D G3DSA:1.10.600.10 3 355 1.1E-112 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_09720 8d23af357333a2890a04fb6d481b68eb 355 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 233 245 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFR_09720 8d23af357333a2890a04fb6d481b68eb 355 Pfam PF00348 Polyprenyl synthetase 40 302 1.2E-50 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFR_30085 285d02fbde4c4c6b08500345e1bc6f88 242 Gene3D G3DSA:3.40.50.1240 7 239 1.3E-43 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_30085 285d02fbde4c4c6b08500345e1bc6f88 242 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 AFR_30085 285d02fbde4c4c6b08500345e1bc6f88 242 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 218 4.5E-37 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_30085 285d02fbde4c4c6b08500345e1bc6f88 242 SMART SM00855 9 177 7.3E-10 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_30085 285d02fbde4c4c6b08500345e1bc6f88 242 SUPERFAMILY SSF53254 8 225 2.08E-44 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_30085 285d02fbde4c4c6b08500345e1bc6f88 242 PIRSF PIRSF000709 8 198 3.7E-17 T 12-10-2018 AFR_07070 9913c2127bac53f49d0eaeab83d09c69 264 SUPERFAMILY SSF52540 17 219 8.79E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07070 9913c2127bac53f49d0eaeab83d09c69 264 Hamap MF_00165 Thymidylate kinase [tmk]. 19 220 13.071 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFR_07070 9913c2127bac53f49d0eaeab83d09c69 264 Pfam PF02223 Thymidylate kinase 25 210 2.6E-16 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFR_07070 9913c2127bac53f49d0eaeab83d09c69 264 Gene3D G3DSA:3.40.50.300 17 220 5.8E-37 T 12-10-2018 AFR_34450 8fa5a76c2191758ba64b5cfabfdd3ac7 224 SMART SM00382 34 222 1.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_34450 8fa5a76c2191758ba64b5cfabfdd3ac7 224 Gene3D G3DSA:3.40.50.300 3 224 1.7E-69 T 12-10-2018 AFR_34450 8fa5a76c2191758ba64b5cfabfdd3ac7 224 SUPERFAMILY SSF52540 5 223 6.97E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34450 8fa5a76c2191758ba64b5cfabfdd3ac7 224 Pfam PF00005 ABC transporter 26 173 3.9E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_34450 8fa5a76c2191758ba64b5cfabfdd3ac7 224 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_39045 384f7ff39ac40e48e8b94ca0be7f4c3e 165 SUPERFAMILY SSF74853 65 154 4.19E-13 T 12-10-2018 IPR036415 Lamin tail domain superfamily AFR_39045 384f7ff39ac40e48e8b94ca0be7f4c3e 165 Pfam PF00932 Lamin Tail Domain 39 154 3.2E-21 T 12-10-2018 IPR001322 Lamin tail domain AFR_21460 fa366a88060b4b28feb2645ee32f9960 202 SUPERFAMILY SSF46689 7 72 1.54E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21460 fa366a88060b4b28feb2645ee32f9960 202 Gene3D G3DSA:1.10.357.10 4 197 3.7E-18 T 12-10-2018 AFR_21460 fa366a88060b4b28feb2645ee32f9960 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 5.4E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 206 396 5.3E-72 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 Gene3D G3DSA:3.40.50.10990 205 376 4.6E-74 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 197 1.6E-87 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 SUPERFAMILY SSF142695 204 375 3.53E-69 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 Pfam PF00925 GTP cyclohydrolase II 206 371 1.9E-71 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 203 399 40.969 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 202 39.038 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 395 54.487 T 12-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 PIRSF PIRSF001259 1 400 1.2E-177 T 12-10-2018 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 SUPERFAMILY SSF55821 3 202 4.35E-84 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 Gene3D G3DSA:3.90.870.10 1 204 1.7E-91 T 12-10-2018 AFR_30510 5a4c0f797d4db814910d69d9da16c265 401 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 198 1.4E-76 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFR_19660 c3f2f0be44fc1996315542c15fa710f1 385 Pfam PF08281 Sigma-70, region 4 86 137 3.2E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_19660 c3f2f0be44fc1996315542c15fa710f1 385 SUPERFAMILY SSF88946 4 74 5.1E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_19660 c3f2f0be44fc1996315542c15fa710f1 385 Gene3D G3DSA:1.10.1740.10 1 56 1.4E-7 T 12-10-2018 AFR_19660 c3f2f0be44fc1996315542c15fa710f1 385 SUPERFAMILY SSF88659 78 138 8.9E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_19660 c3f2f0be44fc1996315542c15fa710f1 385 Gene3D G3DSA:1.10.10.10 91 141 7.4E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19660 c3f2f0be44fc1996315542c15fa710f1 385 Pfam PF04542 Sigma-70 region 2 6 59 3.5E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_04325 513d1e9eb64ae54ba9bbec8e19196139 219 Gene3D G3DSA:2.40.33.20 1 219 5.8E-57 T 12-10-2018 AFR_04325 513d1e9eb64ae54ba9bbec8e19196139 219 SUPERFAMILY SSF50800 7 216 6.28E-50 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_04325 513d1e9eb64ae54ba9bbec8e19196139 219 Pfam PF03473 MOSC domain 62 172 1.2E-20 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 AFR_39665 99a9499072d981829c85ad7df1250f9b 275 SUPERFAMILY SSF161098 3 275 2.62E-72 T 12-10-2018 IPR035906 MetI-like superfamily AFR_39665 99a9499072d981829c85ad7df1250f9b 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 268 8.8E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_39665 99a9499072d981829c85ad7df1250f9b 275 Gene3D G3DSA:1.10.3720.10 2 266 3.3E-66 T 12-10-2018 IPR035906 MetI-like superfamily AFR_21980 fecf818b1738897252cbb65b8e120357 565 Pfam PF00561 alpha/beta hydrolase fold 97 252 2.2E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21980 fecf818b1738897252cbb65b8e120357 565 Pfam PF08386 TAP-like protein 410 514 1.3E-17 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal AFR_21980 fecf818b1738897252cbb65b8e120357 565 SUPERFAMILY SSF53474 94 488 5.73E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_42505 3d34602a82fa8e5931cd1406b790de04 403 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 150 303 3.6E-43 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_42505 3d34602a82fa8e5931cd1406b790de04 403 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 150 303 8.8E-44 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_42505 3d34602a82fa8e5931cd1406b790de04 403 Gene3D G3DSA:1.10.260.150 115 400 4.4E-75 T 12-10-2018 AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 173 3.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 204 3.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 64 75 3.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 110 126 3.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 155 3.4E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 123 151 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 Gene3D G3DSA:3.40.50.720 1 223 1.9E-45 T 12-10-2018 AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 SUPERFAMILY SSF51735 3 206 1.11E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 Pfam PF00106 short chain dehydrogenase 2 179 7.5E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 155 7.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 64 75 7.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16580 6df0ab547dfeef3287d3903c11c0b61a 224 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 116 124 7.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_42580 448c7a64d75dc215792b10ca945a361b 142 Pfam PF02566 OsmC-like protein 40 137 3.9E-19 T 12-10-2018 IPR003718 OsmC/Ohr family AFR_42580 448c7a64d75dc215792b10ca945a361b 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 1.6E-54 T 12-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 AFR_42580 448c7a64d75dc215792b10ca945a361b 142 Gene3D G3DSA:3.30.300.20 1 142 2.5E-41 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_42580 448c7a64d75dc215792b10ca945a361b 142 SUPERFAMILY SSF82784 3 138 2.22E-37 T 12-10-2018 IPR036102 OsmC/Ohr superfamily AFR_32815 a0276c6d707f588606c2ced3694be9fe 40 SUPERFAMILY SSF57840 1 40 4.84E-9 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_32815 a0276c6d707f588606c2ced3694be9fe 40 Pfam PF00444 Ribosomal protein L36 1 40 1.3E-13 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_29105 29cd7103ed28f5ff204bb07f145975ec 395 Pfam PF13378 Enolase C-terminal domain-like 148 347 7.7E-47 T 12-10-2018 IPR029065 Enolase C-terminal domain-like AFR_29105 29cd7103ed28f5ff204bb07f145975ec 395 Gene3D G3DSA:3.20.20.120 116 345 1.3E-56 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_29105 29cd7103ed28f5ff204bb07f145975ec 395 SMART SM00922 137 237 6.3E-19 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFR_29105 29cd7103ed28f5ff204bb07f145975ec 395 SUPERFAMILY SSF51604 106 353 1.31E-51 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_29105 29cd7103ed28f5ff204bb07f145975ec 395 Gene3D G3DSA:3.30.390.10 1 115 1.1E-17 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFR_29105 29cd7103ed28f5ff204bb07f145975ec 395 SUPERFAMILY SSF54826 1 118 3.54E-21 T 12-10-2018 AFR_29105 29cd7103ed28f5ff204bb07f145975ec 395 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 118 2.1E-7 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 SUPERFAMILY SSF46894 137 237 3.87E-28 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 Gene3D G3DSA:1.10.10.10 141 239 3.7E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 SMART SM00862 160 236 1.3E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 Pfam PF00072 Response regulator receiver domain 17 126 6.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 Gene3D G3DSA:3.40.50.2300 8 140 2.2E-38 T 12-10-2018 AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 SMART SM00448 15 125 1.7E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 236 5.3E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_21155 a9bee41b7b3a49cdeaee54d80c676bfa 239 SUPERFAMILY SSF52172 14 140 9.53E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFR_23550 c17af123fe86701efa61c351728b28e4 370 Pfam PF01494 FAD binding domain 3 337 6.7E-21 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_23550 c17af123fe86701efa61c351728b28e4 370 Gene3D G3DSA:3.50.50.60 2 355 2.7E-102 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23550 c17af123fe86701efa61c351728b28e4 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 3.1E-13 T 12-10-2018 AFR_23550 c17af123fe86701efa61c351728b28e4 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.1E-13 T 12-10-2018 AFR_23550 c17af123fe86701efa61c351728b28e4 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 3.1E-13 T 12-10-2018 AFR_23550 c17af123fe86701efa61c351728b28e4 370 SUPERFAMILY SSF51905 3 356 1.35E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25625 98ef56bcb9bbead7feee0e5fd961777e 251 SUPERFAMILY SSF141523 133 244 1.02E-21 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_25625 98ef56bcb9bbead7feee0e5fd961777e 251 SUPERFAMILY SSF47090 57 112 8.11E-5 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_25625 98ef56bcb9bbead7feee0e5fd961777e 251 Gene3D G3DSA:2.40.440.10 134 250 1.2E-22 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_25625 98ef56bcb9bbead7feee0e5fd961777e 251 Pfam PF03734 L,D-transpeptidase catalytic domain 136 243 1.4E-14 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_03340 0bdb7b5ccc6505dd65e65396597e9fdf 371 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 66 274 1.4E-29 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase AFR_03340 0bdb7b5ccc6505dd65e65396597e9fdf 371 SUPERFAMILY SSF51197 66 339 1.83E-45 T 12-10-2018 AFR_03340 0bdb7b5ccc6505dd65e65396597e9fdf 371 Gene3D G3DSA:2.60.120.620 49 315 2.3E-37 T 12-10-2018 AFR_41725 e180eb8ce9480938954226f82e2053af 369 Gene3D G3DSA:2.10.10.20 34 85 4.7E-17 T 12-10-2018 AFR_41725 e180eb8ce9480938954226f82e2053af 369 SUPERFAMILY SSF51055 99 144 2.88E-5 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_41725 e180eb8ce9480938954226f82e2053af 369 Gene3D G3DSA:1.10.530.10 169 369 1.6E-85 T 12-10-2018 AFR_41725 e180eb8ce9480938954226f82e2053af 369 Gene3D G3DSA:2.10.10.20 101 148 5.8E-6 T 12-10-2018 AFR_41725 e180eb8ce9480938954226f82e2053af 369 SMART SM00495 102 146 0.29 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_41725 e180eb8ce9480938954226f82e2053af 369 SMART SM00495 37 81 3.0E-9 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_41725 e180eb8ce9480938954226f82e2053af 369 Pfam PF00182 Chitinase class I 170 369 1.9E-45 T 12-10-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_41725 e180eb8ce9480938954226f82e2053af 369 PIRSF PIRSF001060 1 369 2.2E-82 T 12-10-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_41725 e180eb8ce9480938954226f82e2053af 369 Gene3D G3DSA:3.30.20.10 230 290 1.6E-85 T 12-10-2018 AFR_41725 e180eb8ce9480938954226f82e2053af 369 SUPERFAMILY SSF51055 26 84 2.94E-12 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_41725 e180eb8ce9480938954226f82e2053af 369 SUPERFAMILY SSF53955 166 369 3.66E-69 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_27145 d3ee50371dfbd50a03185f97dd8756cb 233 SUPERFAMILY SSF81606 2 229 1.18E-62 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27145 d3ee50371dfbd50a03185f97dd8756cb 233 Gene3D G3DSA:3.60.40.10 1 230 1.5E-62 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27145 d3ee50371dfbd50a03185f97dd8756cb 233 SMART SM00332 1 227 4.9E-22 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27145 d3ee50371dfbd50a03185f97dd8756cb 233 SMART SM00331 4 229 5.7E-30 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27145 d3ee50371dfbd50a03185f97dd8756cb 233 Pfam PF13672 Protein phosphatase 2C 11 190 2.3E-15 T 12-10-2018 AFR_30605 b5386afed1d7b6013d226044cacc2af9 420 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_30605 b5386afed1d7b6013d226044cacc2af9 420 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 12 417 6.6E-165 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AFR_30605 b5386afed1d7b6013d226044cacc2af9 420 Pfam PF00202 Aminotransferase class-III 24 416 4.1E-119 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_30605 b5386afed1d7b6013d226044cacc2af9 420 SUPERFAMILY SSF53383 5 418 1.39E-117 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_30605 b5386afed1d7b6013d226044cacc2af9 420 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 420 47.371 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AFR_30605 b5386afed1d7b6013d226044cacc2af9 420 Gene3D G3DSA:3.40.640.10 60 326 1.1E-158 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_30605 b5386afed1d7b6013d226044cacc2af9 420 Gene3D G3DSA:3.90.1150.10 8 409 1.1E-158 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_38145 15e31783e84737b86b66563b9530129f 312 Pfam PF03193 RsgA GTPase 62 240 2.8E-39 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 AFR_38145 15e31783e84737b86b66563b9530129f 312 SUPERFAMILY SSF52540 82 300 8.46E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38145 15e31783e84737b86b66563b9530129f 312 Gene3D G3DSA:3.40.50.300 69 240 2.8E-36 T 12-10-2018 AFR_38145 15e31783e84737b86b66563b9530129f 312 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 36 298 2.8E-42 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 AFR_38145 15e31783e84737b86b66563b9530129f 312 Gene3D G3DSA:1.10.40.50 241 309 9.7E-6 T 12-10-2018 AFR_32955 9c5f3bbf3555fd0d4a820211c9a506d1 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 116 9.6E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_32955 9c5f3bbf3555fd0d4a820211c9a506d1 121 Gene3D G3DSA:3.10.180.10 5 121 2.6E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_32955 9c5f3bbf3555fd0d4a820211c9a506d1 121 SUPERFAMILY SSF54593 8 118 5.77E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_06220 a31513884458486964beac03f962b519 530 Pfam PF04471 Restriction endonuclease 407 514 1.5E-5 T 12-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFR_14405 9147a569095e2816a805156aff716d2d 158 Pfam PF08281 Sigma-70, region 4 84 136 3.1E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_14405 9147a569095e2816a805156aff716d2d 158 Gene3D G3DSA:1.10.1740.10 1 61 1.5E-7 T 12-10-2018 AFR_14405 9147a569095e2816a805156aff716d2d 158 Pfam PF04542 Sigma-70 region 2 8 61 3.1E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14405 9147a569095e2816a805156aff716d2d 158 SUPERFAMILY SSF88659 84 140 4.86E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_14405 9147a569095e2816a805156aff716d2d 158 SUPERFAMILY SSF88946 5 74 3.02E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14405 9147a569095e2816a805156aff716d2d 158 Gene3D G3DSA:1.10.10.10 67 141 4.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14405 9147a569095e2816a805156aff716d2d 158 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 1 141 1.6E-42 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_14405 9147a569095e2816a805156aff716d2d 158 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 138 8.8E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_36180 b7e12abf64213ebc7b39ea023557759a 514 Pfam PF00355 Rieske [2Fe-2S] domain 462 502 4.6E-8 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFR_36180 b7e12abf64213ebc7b39ea023557759a 514 Pfam PF13483 Beta-lactamase superfamily domain 3 81 5.3E-7 T 12-10-2018 AFR_36180 b7e12abf64213ebc7b39ea023557759a 514 Gene3D G3DSA:2.102.10.10 456 510 4.6E-10 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_36180 b7e12abf64213ebc7b39ea023557759a 514 Gene3D G3DSA:3.60.15.10 1 232 4.2E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_36180 b7e12abf64213ebc7b39ea023557759a 514 SUPERFAMILY SSF50022 462 502 1.31E-11 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_36180 b7e12abf64213ebc7b39ea023557759a 514 SUPERFAMILY SSF56281 2 229 1.4E-15 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_23690 759a66c26fbaf3abe08f67f1c5a8a019 83 SUPERFAMILY SSF51182 1 60 1.42E-14 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_23690 759a66c26fbaf3abe08f67f1c5a8a019 83 Pfam PF07883 Cupin domain 2 39 2.8E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_23690 759a66c26fbaf3abe08f67f1c5a8a019 83 Gene3D G3DSA:2.60.120.10 1 79 5.7E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_16720 14a8ec3781a97d2636a4c8786334c508 298 Pfam PF07676 WD40-like Beta Propeller Repeat 242 260 0.0018 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_16720 14a8ec3781a97d2636a4c8786334c508 298 Pfam PF07676 WD40-like Beta Propeller Repeat 201 214 0.12 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_16720 14a8ec3781a97d2636a4c8786334c508 298 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 162 200 7.3E-5 T 12-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 AFR_16720 14a8ec3781a97d2636a4c8786334c508 298 SUPERFAMILY SSF82171 113 264 3.14E-25 T 12-10-2018 AFR_16720 14a8ec3781a97d2636a4c8786334c508 298 Gene3D G3DSA:2.120.10.30 86 296 1.7E-30 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 Gene3D G3DSA:3.40.190.10 168 268 1.6E-41 T 12-10-2018 AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 Gene3D G3DSA:1.10.10.10 1 88 3.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 Pfam PF03466 LysR substrate binding domain 90 291 3.0E-38 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.2E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 SUPERFAMILY SSF46785 3 111 3.86E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 Gene3D G3DSA:3.40.190.10 91 275 1.6E-41 T 12-10-2018 AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 SUPERFAMILY SSF53850 91 292 2.9E-33 T 12-10-2018 AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_42100 54318f5d7b2dc008c57643bc15a8f05b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 SMART SM00387 314 407 6.9E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 SUPERFAMILY SSF55874 288 405 5.24E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 385 7.7E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 7.7E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 404 7.7E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 Pfam PF07730 Histidine kinase 210 276 3.9E-18 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 Gene3D G3DSA:3.30.565.10 276 405 6.7E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 406 4.4E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_34190 ca1c0065316a7fe6a08f03365e6149ba 411 PIRSF PIRSF037434 10 411 1.1E-65 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 Pfam PF00067 Cytochrome P450 213 360 2.6E-23 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00385 P450 superfamily signature 264 275 2.1E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00385 P450 superfamily signature 331 340 2.1E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00385 P450 superfamily signature 229 246 2.1E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00385 P450 superfamily signature 340 351 2.1E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 SUPERFAMILY SSF48264 5 392 3.01E-92 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 Gene3D G3DSA:1.10.630.10 5 394 7.0E-122 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 87 98 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 264 275 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 134 150 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 188 210 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 282 309 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 331 340 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 151 166 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 310 325 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 PRINTS PR00359 B-class P450 signature 340 351 2.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_30290 1dfb8ec4cf08f955c536c26547e1945e 394 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_06430 8a128058474e1fbe6bfd23ba428ca7e8 271 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 67 4.3E-12 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AFR_06430 8a128058474e1fbe6bfd23ba428ca7e8 271 SUPERFAMILY SSF53697 82 255 2.2E-14 T 12-10-2018 AFR_06430 8a128058474e1fbe6bfd23ba428ca7e8 271 SUPERFAMILY SSF46689 9 68 3.23E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06430 8a128058474e1fbe6bfd23ba428ca7e8 271 Pfam PF01380 SIS domain 169 241 9.7E-6 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_06430 8a128058474e1fbe6bfd23ba428ca7e8 271 Gene3D G3DSA:1.10.10.10 6 72 1.0E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06430 8a128058474e1fbe6bfd23ba428ca7e8 271 Gene3D G3DSA:3.40.50.10490 80 266 4.9E-23 T 12-10-2018 AFR_06105 d379e4c63781270ec0eb3298f03fbae7 217 SUPERFAMILY SSF55961 6 119 4.34E-10 T 12-10-2018 AFR_06105 d379e4c63781270ec0eb3298f03fbae7 217 Gene3D G3DSA:3.30.530.20 1 136 9.5E-6 T 12-10-2018 IPR023393 START-like domain superfamily AFR_07065 f68449706a155a45c221cb45425dfe89 194 Pfam PF14907 Uncharacterised nucleotidyltransferase 9 175 2.9E-9 T 12-10-2018 IPR039498 Uncharacterised nucleotidyltransferase AFR_07065 f68449706a155a45c221cb45425dfe89 194 Gene3D G3DSA:3.30.460.40 2 137 6.8E-12 T 12-10-2018 AFR_07065 f68449706a155a45c221cb45425dfe89 194 SUPERFAMILY SSF81301 8 141 2.73E-23 T 12-10-2018 AFR_20075 ba9bae2b4427d072504904cfda30b37f 212 Pfam PF12277 Protein of unknown function (DUF3618) 3 47 2.2E-14 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 AFR_20075 ba9bae2b4427d072504904cfda30b37f 212 Gene3D G3DSA:1.10.287.700 128 212 1.3E-6 T 12-10-2018 AFR_20075 ba9bae2b4427d072504904cfda30b37f 212 Gene3D G3DSA:1.20.120.20 2 112 2.6E-5 T 12-10-2018 AFR_39220 2f651497bf3e4f141ffd2d593be37c45 183 Pfam PF14030 Protein of unknown function (DUF4245) 16 182 2.5E-38 T 12-10-2018 IPR025339 Protein of unknown function DUF4245 AFR_43000 29531afd2033487598fdc6e94e8f8631 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_43000 29531afd2033487598fdc6e94e8f8631 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.615 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_43000 29531afd2033487598fdc6e94e8f8631 45 Pfam PF00468 Ribosomal protein L34 3 45 7.8E-21 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_43000 29531afd2033487598fdc6e94e8f8631 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 6.9E-21 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_43000 29531afd2033487598fdc6e94e8f8631 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 2.0E-13 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_14860 0e53484d3d46bbe0c0718dc2b9b8f4d9 241 Pfam PF12697 Alpha/beta hydrolase family 6 229 2.7E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_14860 0e53484d3d46bbe0c0718dc2b9b8f4d9 241 Gene3D G3DSA:3.40.50.1820 1 238 4.6E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14860 0e53484d3d46bbe0c0718dc2b9b8f4d9 241 SUPERFAMILY SSF53474 3 234 5.03E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_05770 5026ba9820f499b92630aac0a4919c98 548 SUPERFAMILY SSF55874 337 504 1.83E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_05770 5026ba9820f499b92630aac0a4919c98 548 Pfam PF00512 His Kinase A (phospho-acceptor) domain 281 347 2.6E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 SMART SM00387 393 504 1.1E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_05770 5026ba9820f499b92630aac0a4919c98 548 SMART SM00304 220 272 6.4E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 SMART SM00388 280 347 1.2E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 Gene3D G3DSA:1.10.287.130 276 352 5.8E-18 T 12-10-2018 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 Gene3D G3DSA:1.20.1480.50 187 275 8.6E-10 T 12-10-2018 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 SUPERFAMILY SSF47384 263 347 4.12E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 Pfam PF00672 HAMP domain 220 269 3.0E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 457 4.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 4.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 501 4.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 482 4.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 502 1.7E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_05770 5026ba9820f499b92630aac0a4919c98 548 SUPERFAMILY SSF158472 220 270 2.35E-8 T 12-10-2018 AFR_05770 5026ba9820f499b92630aac0a4919c98 548 Gene3D G3DSA:3.30.565.10 353 504 1.9E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 Gene3D G3DSA:3.40.1690.10 211 351 7.5E-53 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 SUPERFAMILY SSF160544 238 344 1.57E-35 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 6 28 3.0E-33 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 202 220 3.0E-33 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 222 239 3.0E-33 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 295 316 3.0E-33 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 266 281 3.0E-33 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFR_40525 8c80b89c8ac4d4f8d2bb188e88902e36 363 Pfam PF01312 FlhB HrpN YscU SpaS Family 3 340 4.6E-110 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFR_20660 e2f21e496b2220b4183ab58e50ae7101 223 SUPERFAMILY SSF53335 17 221 3.04E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_20660 e2f21e496b2220b4183ab58e50ae7101 223 Pfam PF13649 Methyltransferase domain 30 122 1.4E-12 T 12-10-2018 AFR_20660 e2f21e496b2220b4183ab58e50ae7101 223 Gene3D G3DSA:2.20.25.570 130 181 3.2E-31 T 12-10-2018 AFR_20660 e2f21e496b2220b4183ab58e50ae7101 223 Gene3D G3DSA:3.40.50.150 27 214 3.2E-31 T 12-10-2018 AFR_37820 a204e8adfaac01bbcee59cf292b97ffa 402 Gene3D G3DSA:3.20.20.80 111 402 1.5E-76 T 12-10-2018 AFR_37820 a204e8adfaac01bbcee59cf292b97ffa 402 SMART SM00495 37 82 2.7E-11 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_37820 a204e8adfaac01bbcee59cf292b97ffa 402 Gene3D G3DSA:2.10.10.20 34 86 1.2E-17 T 12-10-2018 AFR_37820 a204e8adfaac01bbcee59cf292b97ffa 402 SUPERFAMILY SSF51445 109 378 1.82E-17 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_37820 a204e8adfaac01bbcee59cf292b97ffa 402 SUPERFAMILY SSF51055 34 85 7.46E-14 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_37820 a204e8adfaac01bbcee59cf292b97ffa 402 Pfam PF00704 Glycosyl hydrolases family 18 135 312 9.1E-8 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_06295 95c9df147bc6d46e9d8871d7a45bbc12 454 Gene3D G3DSA:1.20.1250.20 257 453 9.4E-16 T 12-10-2018 AFR_06295 95c9df147bc6d46e9d8871d7a45bbc12 454 Gene3D G3DSA:1.20.1720.10 7 220 2.5E-38 T 12-10-2018 AFR_06295 95c9df147bc6d46e9d8871d7a45bbc12 454 SUPERFAMILY SSF103473 3 446 1.18E-50 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_06295 95c9df147bc6d46e9d8871d7a45bbc12 454 Pfam PF07690 Major Facilitator Superfamily 12 406 1.4E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 Gene3D G3DSA:3.40.50.720 2 250 3.2E-69 T 12-10-2018 AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 1.3E-51 T 12-10-2018 AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 SUPERFAMILY SSF51735 5 249 1.23E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29130 5038c5d56336d6bd6082212e5b7b4e81 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 Pfam PF01595 Domain of unknown function DUF21 22 199 9.5E-30 T 12-10-2018 IPR002550 CNNM, transmembrane domain AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 SUPERFAMILY SSF56176 353 440 1.74E-16 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 Gene3D G3DSA:3.10.580.10 194 344 4.9E-57 T 12-10-2018 AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 Pfam PF03471 Transporter associated domain 354 430 3.3E-15 T 12-10-2018 IPR005170 Transporter-associated domain AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 SMART SM01091 352 432 2.0E-22 T 12-10-2018 IPR005170 Transporter-associated domain AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 SUPERFAMILY SSF54631 209 355 4.93E-37 T 12-10-2018 AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 Gene3D G3DSA:3.30.465.10 345 431 2.0E-20 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 Pfam PF00571 CBS domain 216 269 2.8E-5 T 12-10-2018 IPR000644 CBS domain AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 Pfam PF00571 CBS domain 283 337 3.3E-7 T 12-10-2018 IPR000644 CBS domain AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 SMART SM00116 289 337 5.0 T 12-10-2018 IPR000644 CBS domain AFR_07965 b5c8f7347fe7ceea182e6d0cc27cfd88 455 SMART SM00116 223 272 0.0026 T 12-10-2018 IPR000644 CBS domain AFR_06915 7dca14ddde8f8fa8227bfdebeca443d9 162 Pfam PF00293 NUDIX domain 22 133 9.8E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_06915 7dca14ddde8f8fa8227bfdebeca443d9 162 SUPERFAMILY SSF55811 8 144 1.62E-31 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_06915 7dca14ddde8f8fa8227bfdebeca443d9 162 Gene3D G3DSA:3.90.79.10 1 142 3.4E-39 T 12-10-2018 AFR_37315 a5ae0d5b2a79cfc797b8b49b44da570b 191 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 179 7.3E-52 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFR_37315 a5ae0d5b2a79cfc797b8b49b44da570b 191 SUPERFAMILY SSF89028 7 184 5.69E-56 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFR_37315 a5ae0d5b2a79cfc797b8b49b44da570b 191 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 184 8.0E-41 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFR_37315 a5ae0d5b2a79cfc797b8b49b44da570b 191 Gene3D G3DSA:1.20.1200.10 29 191 2.0E-57 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFR_37315 a5ae0d5b2a79cfc797b8b49b44da570b 191 Pfam PF01923 Cobalamin adenosyltransferase 8 175 2.9E-55 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFR_12545 90ecb037867c22be3c90d22024650d0e 386 Gene3D G3DSA:3.30.565.10 256 380 1.2E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12545 90ecb037867c22be3c90d22024650d0e 386 SUPERFAMILY SSF55874 269 373 2.01E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12545 90ecb037867c22be3c90d22024650d0e 386 Pfam PF07730 Histidine kinase 187 251 7.5E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_34415 457a5fa41dc373913257c6f4adc4482e 115 Pfam PF00085 Thioredoxin 7 105 3.2E-23 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFR_34415 457a5fa41dc373913257c6f4adc4482e 115 SUPERFAMILY SSF52833 3 107 2.21E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_34415 457a5fa41dc373913257c6f4adc4482e 115 PIRSF PIRSF000077 3 109 4.0E-31 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFR_34415 457a5fa41dc373913257c6f4adc4482e 115 ProSitePatterns PS00194 Thioredoxin family active site. 26 44 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFR_34415 457a5fa41dc373913257c6f4adc4482e 115 Gene3D G3DSA:3.40.30.10 2 109 3.6E-27 T 12-10-2018 AFR_24140 7892b2b9b8942c05d7641893c05ab389 282 SUPERFAMILY SSF47413 11 71 4.44E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_24140 7892b2b9b8942c05d7641893c05ab389 282 Pfam PF13560 Helix-turn-helix domain 13 74 2.8E-13 T 12-10-2018 AFR_24140 7892b2b9b8942c05d7641893c05ab389 282 Gene3D G3DSA:1.10.260.40 5 75 1.2E-6 T 12-10-2018 AFR_03555 c127e93b7117f93e7d3e1bb6506bb90f 185 Gene3D G3DSA:3.40.430.10 11 182 4.9E-33 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_03555 c127e93b7117f93e7d3e1bb6506bb90f 185 Pfam PF01872 RibD C-terminal domain 12 168 1.1E-13 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_03555 c127e93b7117f93e7d3e1bb6506bb90f 185 SUPERFAMILY SSF53597 12 167 9.82E-20 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_17155 db213710e495a31ee7bd08279c2202c6 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 325 2.9E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_06285 b93923019956d080982fac1c7143fa73 585 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 480 9.8E-146 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 1.9E-207 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFR_06285 b93923019956d080982fac1c7143fa73 585 SUPERFAMILY SSF81442 26 535 3.66E-167 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 Gene3D G3DSA:1.20.210.10 16 541 1.8E-198 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06285 b93923019956d080982fac1c7143fa73 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 2.7E-91 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06270 69a30be7b5c5562b7befce68758fb504 355 Pfam PF01068 ATP dependent DNA ligase domain 165 351 6.1E-18 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AFR_06270 69a30be7b5c5562b7befce68758fb504 355 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 5 148 1.4E-44 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain AFR_06270 69a30be7b5c5562b7befce68758fb504 355 Gene3D G3DSA:3.30.470.30 188 310 2.7E-43 T 12-10-2018 AFR_06270 69a30be7b5c5562b7befce68758fb504 355 Pfam PF13298 DNA polymerase Ligase (LigD) 37 135 4.7E-32 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain AFR_06270 69a30be7b5c5562b7befce68758fb504 355 Gene3D G3DSA:3.30.1490.70 176 351 2.7E-43 T 12-10-2018 AFR_06270 69a30be7b5c5562b7befce68758fb504 355 SUPERFAMILY SSF56091 153 351 5.47E-28 T 12-10-2018 AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 Pfam PF00563 EAL domain 769 1006 4.0E-73 T 12-10-2018 IPR001633 EAL domain AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 Gene3D G3DSA:3.30.450.40 317 464 3.3E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 SMART SM00267 582 753 2.8E-66 T 12-10-2018 IPR000160 GGDEF domain AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 Pfam PF08448 PAS fold 478 584 1.6E-9 T 12-10-2018 IPR013656 PAS fold-4 AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 467 589 3.9E-13 T 12-10-2018 IPR000014 PAS domain AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 589 750 2.9E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 Gene3D G3DSA:3.20.20.450 766 1020 3.6E-97 T 12-10-2018 IPR035919 EAL domain superfamily AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 SUPERFAMILY SSF55785 464 580 9.02E-15 T 12-10-2018 IPR035965 PAS domain superfamily AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 SUPERFAMILY SSF55073 598 754 5.73E-47 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 Gene3D G3DSA:3.30.70.270 588 765 1.4E-56 T 12-10-2018 AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 SMART SM00091 471 534 2.1E-6 T 12-10-2018 IPR000014 PAS domain AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 SMART SM00052 763 1011 2.4E-106 T 12-10-2018 IPR001633 EAL domain AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 SUPERFAMILY SSF141868 769 1019 9.68E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 Pfam PF00990 Diguanylate cyclase, GGDEF domain 593 749 1.8E-46 T 12-10-2018 IPR000160 GGDEF domain AFR_34815 2a06e05f1942846828298ed83b9b5a51 1025 Gene3D G3DSA:3.30.450.20 465 587 4.0E-17 T 12-10-2018 AFR_26355 456d6fd004864f382a030bbc2e977aba 328 Pfam PF13280 WYL domain 149 316 1.6E-30 T 12-10-2018 IPR026881 WYL domain AFR_26355 456d6fd004864f382a030bbc2e977aba 328 PIRSF PIRSF016838 10 325 6.1E-110 T 12-10-2018 IPR028349 Protein PafC AFR_02215 b5d9fd271142cd797f717f2c81274686 299 SUPERFAMILY SSF74650 4 293 6.09E-61 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_02215 b5d9fd271142cd797f717f2c81274686 299 Pfam PF01263 Aldose 1-epimerase 4 291 1.2E-44 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 AFR_02215 b5d9fd271142cd797f717f2c81274686 299 Gene3D G3DSA:2.70.98.10 2 296 1.7E-75 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_06965 60190aebf7d51c9d9337536403b25516 987 Gene3D G3DSA:1.10.287.130 425 473 2.2E-10 T 12-10-2018 AFR_06965 60190aebf7d51c9d9337536403b25516 987 SMART SM00387 515 625 1.2E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_06965 60190aebf7d51c9d9337536403b25516 987 Pfam PF08376 Nitrate and nitrite sensing 60 296 3.8E-31 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein AFR_06965 60190aebf7d51c9d9337536403b25516 987 Pfam PF00672 HAMP domain 334 399 2.7E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_06965 60190aebf7d51c9d9337536403b25516 987 Gene3D G3DSA:3.30.565.10 474 622 2.2E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_06965 60190aebf7d51c9d9337536403b25516 987 SUPERFAMILY SSF55874 517 622 9.3E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_04505 2fc7525bfcd13afbc07b676c756fa78b 213 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 203 4.6E-87 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04505 2fc7525bfcd13afbc07b676c756fa78b 213 Gene3D G3DSA:2.40.50.620 30 93 1.1E-18 T 12-10-2018 AFR_04505 2fc7525bfcd13afbc07b676c756fa78b 213 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 206 38.85 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04505 2fc7525bfcd13afbc07b676c756fa78b 213 Gene3D G3DSA:2.40.30.10 119 209 1.5E-18 T 12-10-2018 AFR_04505 2fc7525bfcd13afbc07b676c756fa78b 213 ProSitePatterns PS00474 Ribosomal protein L3 signature. 100 123 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site AFR_04505 2fc7525bfcd13afbc07b676c756fa78b 213 SUPERFAMILY SSF50447 2 209 5.03E-79 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_04505 2fc7525bfcd13afbc07b676c756fa78b 213 Pfam PF00297 Ribosomal protein L3 95 176 5.1E-15 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_32100 bf80a9c38d244b9b6b4f6d232d5f0d5e 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 1 254 8.0E-19 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_32100 bf80a9c38d244b9b6b4f6d232d5f0d5e 263 Gene3D G3DSA:3.60.10.10 1 262 3.0E-41 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_32100 bf80a9c38d244b9b6b4f6d232d5f0d5e 263 SUPERFAMILY SSF56219 1 262 3.66E-31 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_08820 8cc2d9fc180b2e0be85af2642f2bb511 166 Gene3D G3DSA:2.40.380.10 16 165 6.9E-11 T 12-10-2018 IPR035930 FomD-like superfamily AFR_08820 8cc2d9fc180b2e0be85af2642f2bb511 166 Pfam PF04167 Protein of unknown function (DUF402) 54 120 1.3E-16 T 12-10-2018 IPR007295 Domain of unknown function DUF402 AFR_08820 8cc2d9fc180b2e0be85af2642f2bb511 166 SUPERFAMILY SSF159234 45 162 7.72E-18 T 12-10-2018 IPR035930 FomD-like superfamily AFR_12075 e0bf64c493e51046a0a09ce34051bf26 413 SUPERFAMILY SSF52200 3 129 1.57E-12 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_12075 e0bf64c493e51046a0a09ce34051bf26 413 Gene3D G3DSA:3.40.50.10140 2 114 3.5E-10 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_12075 e0bf64c493e51046a0a09ce34051bf26 413 Pfam PF13676 TIR domain 4 111 1.7E-12 T 12-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 AFR_24310 d61379ef476be6a17f86cc9de84d08ef 364 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 364 72.807 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_24310 d61379ef476be6a17f86cc9de84d08ef 364 Gene3D G3DSA:3.30.590.20 2 363 3.8E-108 T 12-10-2018 AFR_24310 d61379ef476be6a17f86cc9de84d08ef 364 SUPERFAMILY SSF55931 4 360 3.92E-87 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_24310 d61379ef476be6a17f86cc9de84d08ef 364 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 6 284 6.8E-43 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_24310 d61379ef476be6a17f86cc9de84d08ef 364 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 5 288 2.4E-73 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 Gene3D G3DSA:1.10.10.10 820 905 1.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 Pfam PF00196 Bacterial regulatory proteins, luxR family 851 901 3.2E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 Gene3D G3DSA:3.40.50.300 1 180 1.5E-5 T 12-10-2018 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 SMART SM00421 848 905 3.3E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 881 893 1.9E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 851 865 1.9E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 865 881 1.9E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 SUPERFAMILY SSF52540 8 178 6.44E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 Gene3D G3DSA:1.25.40.10 447 748 3.2E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 Pfam PF13191 AAA ATPase domain 9 160 6.4E-18 T 12-10-2018 AFR_20600 a73f5d0420f5dbf26b3c0c66403aa4e2 921 SUPERFAMILY SSF46894 841 903 9.52E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_17320 0a42826d44f94afe0c0fd376bcb99693 218 SUPERFAMILY SSF52540 2 216 6.14E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_17320 0a42826d44f94afe0c0fd376bcb99693 218 Pfam PF00005 ABC transporter 19 166 6.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_17320 0a42826d44f94afe0c0fd376bcb99693 218 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_17320 0a42826d44f94afe0c0fd376bcb99693 218 Gene3D G3DSA:3.40.50.300 1 218 6.8E-65 T 12-10-2018 AFR_17320 0a42826d44f94afe0c0fd376bcb99693 218 SMART SM00382 27 214 2.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22250 7d9a3d0f5361a4f2cf1239ee81479c15 288 SUPERFAMILY SSF161098 85 270 2.75E-28 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22250 7d9a3d0f5361a4f2cf1239ee81479c15 288 Gene3D G3DSA:1.10.3720.10 87 278 5.3E-22 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22250 7d9a3d0f5361a4f2cf1239ee81479c15 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 273 6.9E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_16655 5ae47eaca561241069bdac4ffa022bb3 704 Gene3D G3DSA:1.10.3470.10 23 359 2.4E-71 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_16655 5ae47eaca561241069bdac4ffa022bb3 704 Gene3D G3DSA:1.10.3470.10 377 704 1.7E-85 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_16655 5ae47eaca561241069bdac4ffa022bb3 704 Pfam PF01032 FecCD transport family 36 357 5.4E-63 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_16655 5ae47eaca561241069bdac4ffa022bb3 704 Pfam PF01032 FecCD transport family 393 699 1.7E-79 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_16655 5ae47eaca561241069bdac4ffa022bb3 704 SUPERFAMILY SSF81345 376 699 3.4E-73 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_16655 5ae47eaca561241069bdac4ffa022bb3 704 SUPERFAMILY SSF81345 25 357 8.24E-56 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_29135 80eb7bcf8176d8b08279c1083be9ea9c 120 SUPERFAMILY SSF46785 15 117 2.21E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29135 80eb7bcf8176d8b08279c1083be9ea9c 120 Pfam PF01638 HxlR-like helix-turn-helix 29 116 5.8E-22 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_29135 80eb7bcf8176d8b08279c1083be9ea9c 120 Gene3D G3DSA:1.10.10.10 8 120 7.7E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15810 ea5973aaf3c6e43cb8ac61e73eed5728 296 PIRSF PIRSF036979 202 277 3.1E-5 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_15810 ea5973aaf3c6e43cb8ac61e73eed5728 296 PIRSF PIRSF036979 1 135 1.0E-4 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_15810 ea5973aaf3c6e43cb8ac61e73eed5728 296 PRINTS PR00116 Arginase signature 215 244 1.8E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_15810 ea5973aaf3c6e43cb8ac61e73eed5728 296 PRINTS PR00116 Arginase signature 92 107 1.8E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_15810 ea5973aaf3c6e43cb8ac61e73eed5728 296 SUPERFAMILY SSF52768 4 284 3.96E-38 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily AFR_15810 ea5973aaf3c6e43cb8ac61e73eed5728 296 Pfam PF00491 Arginase family 5 277 7.7E-24 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_15810 ea5973aaf3c6e43cb8ac61e73eed5728 296 Gene3D G3DSA:3.40.800.10 7 287 5.8E-50 T 12-10-2018 AFR_13285 6d417cb5133175b6a356f02ef66f6415 303 Gene3D G3DSA:3.20.20.100 1 301 4.3E-66 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_13285 6d417cb5133175b6a356f02ef66f6415 303 SUPERFAMILY SSF51430 1 274 2.62E-63 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_13285 6d417cb5133175b6a356f02ef66f6415 303 PRINTS PR00069 Aldo-keto reductase signature 33 57 6.7E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_13285 6d417cb5133175b6a356f02ef66f6415 303 PRINTS PR00069 Aldo-keto reductase signature 205 229 6.7E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_13285 6d417cb5133175b6a356f02ef66f6415 303 PRINTS PR00069 Aldo-keto reductase signature 135 152 6.7E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_13285 6d417cb5133175b6a356f02ef66f6415 303 Pfam PF00248 Aldo/keto reductase family 3 274 1.3E-45 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_04180 1e71f100b2f408fd53439e869a8796cc 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 204 3.9E-7 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_04180 1e71f100b2f408fd53439e869a8796cc 309 Gene3D G3DSA:3.40.50.720 5 306 2.9E-33 T 12-10-2018 AFR_04180 1e71f100b2f408fd53439e869a8796cc 309 SUPERFAMILY SSF51735 5 296 6.68E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_05740 5e908c8266a64fffaf2c72b55a4ef75f 289 Pfam PF13560 Helix-turn-helix domain 19 77 1.4E-13 T 12-10-2018 AFR_05740 5e908c8266a64fffaf2c72b55a4ef75f 289 SMART SM00530 23 76 4.1E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_05740 5e908c8266a64fffaf2c72b55a4ef75f 289 SUPERFAMILY SSF47413 13 80 8.73E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_05740 5e908c8266a64fffaf2c72b55a4ef75f 289 Gene3D G3DSA:1.10.260.40 15 88 1.9E-8 T 12-10-2018 AFR_37795 c2d492f3234287315362936bdb452eae 286 SMART SM00752 5 262 0.0074 T 12-10-2018 IPR011020 HTTM Reactome: R-HSA-159740 AFR_01025 88d735d13519facef612c08342fe50bb 360 Gene3D G3DSA:3.30.360.10 129 339 2.0E-33 T 12-10-2018 AFR_01025 88d735d13519facef612c08342fe50bb 360 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 119 1.1E-14 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_01025 88d735d13519facef612c08342fe50bb 360 SUPERFAMILY SSF51735 4 150 2.04E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_01025 88d735d13519facef612c08342fe50bb 360 Gene3D G3DSA:3.40.50.720 2 126 1.5E-27 T 12-10-2018 AFR_01025 88d735d13519facef612c08342fe50bb 360 SUPERFAMILY SSF55347 130 278 4.41E-30 T 12-10-2018 AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 158 1.0E-43 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 Pfam PF08281 Sigma-70, region 4 101 153 1.8E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 SUPERFAMILY SSF88659 97 157 5.05E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 Gene3D G3DSA:1.10.1740.10 2 77 9.2E-10 T 12-10-2018 AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 Pfam PF04542 Sigma-70 region 2 16 79 2.6E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 Gene3D G3DSA:1.10.10.10 83 159 1.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 156 1.2E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_16420 8feddc0efa2b4e4074e4556d9d356d02 169 SUPERFAMILY SSF88946 10 92 1.26E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_22435 fe640a8812c8da62ffb75cd4d84e59e6 275 Gene3D G3DSA:1.10.3720.10 2 267 1.7E-50 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22435 fe640a8812c8da62ffb75cd4d84e59e6 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 270 3.2E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_22435 fe640a8812c8da62ffb75cd4d84e59e6 275 SUPERFAMILY SSF161098 3 275 6.67E-59 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41465 db4cc65e2f9a83e9d15d0035f240351e 119 SUPERFAMILY SSF55620 3 119 1.67E-35 T 12-10-2018 AFR_41465 db4cc65e2f9a83e9d15d0035f240351e 119 SMART SM00905 5 117 3.2E-49 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFR_41465 db4cc65e2f9a83e9d15d0035f240351e 119 Pfam PF02152 Dihydroneopterin aldolase 5 115 1.6E-32 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFR_41465 db4cc65e2f9a83e9d15d0035f240351e 119 TIGRFAM TIGR00526 folB_dom: FolB domain 3 119 2.5E-32 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFR_41465 db4cc65e2f9a83e9d15d0035f240351e 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 2.4E-37 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFR_41465 db4cc65e2f9a83e9d15d0035f240351e 119 Gene3D G3DSA:3.30.1130.10 1 119 1.1E-42 T 12-10-2018 AFR_09785 ca6c880f7eed77b6dc36851a9961a87c 137 Gene3D G3DSA:2.30.110.10 5 137 2.9E-20 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_09785 ca6c880f7eed77b6dc36851a9961a87c 137 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 90 4.8E-8 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_09785 ca6c880f7eed77b6dc36851a9961a87c 137 SUPERFAMILY SSF50475 3 133 1.87E-19 T 12-10-2018 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 Gene3D G3DSA:1.10.10.2730 246 288 9.1E-12 T 12-10-2018 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 SUPERFAMILY SSF51215 23 103 1.96E-10 T 12-10-2018 IPR037923 Transcription regulator HTH-like AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 SUPERFAMILY SSF46689 187 236 1.52E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 SUPERFAMILY SSF46689 240 292 3.85E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 SMART SM00342 203 286 1.5E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 Pfam PF12833 Helix-turn-helix domain 209 288 2.8E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 Pfam PF02311 AraC-like ligand binding domain 31 105 9.9E-9 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 Gene3D G3DSA:1.10.10.60 184 245 6.5E-13 T 12-10-2018 AFR_19355 ba292c4c452971bb4e165d90e5eea6fd 306 Gene3D G3DSA:2.60.120.10 5 90 4.3E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_35720 9b4082d0a75a78e91cf2d0dc6e155019 506 Gene3D G3DSA:3.40.630.10 32 325 2.0E-81 T 12-10-2018 AFR_35720 9b4082d0a75a78e91cf2d0dc6e155019 506 SUPERFAMILY SSF49899 396 505 1.19E-7 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_35720 9b4082d0a75a78e91cf2d0dc6e155019 506 SUPERFAMILY SSF53187 40 319 2.02E-68 T 12-10-2018 AFR_35720 9b4082d0a75a78e91cf2d0dc6e155019 506 Pfam PF04389 Peptidase family M28 96 312 1.5E-45 T 12-10-2018 IPR007484 Peptidase M28 AFR_23425 c1010928c65d2569f393cbe22ced3d0a 215 Gene3D G3DSA:3.40.50.2000 1 172 6.6E-50 T 12-10-2018 AFR_23425 c1010928c65d2569f393cbe22ced3d0a 215 SUPERFAMILY SSF53756 1 160 7.07E-22 T 12-10-2018 AFR_23425 c1010928c65d2569f393cbe22ced3d0a 215 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 1 117 9.0E-11 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_10755 430ec33f5000972076ef95a10a01041f 287 SUPERFAMILY SSF47413 12 73 3.13E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_10755 430ec33f5000972076ef95a10a01041f 287 SMART SM00530 17 72 1.8E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_10755 430ec33f5000972076ef95a10a01041f 287 Pfam PF13560 Helix-turn-helix domain 17 72 1.5E-6 T 12-10-2018 AFR_02905 132f4ce4efc7672807392056e9af1387 187 SUPERFAMILY SSF48498 77 172 2.87E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02905 132f4ce4efc7672807392056e9af1387 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 6.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02905 132f4ce4efc7672807392056e9af1387 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02905 132f4ce4efc7672807392056e9af1387 187 SUPERFAMILY SSF46689 3 83 1.64E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_02905 132f4ce4efc7672807392056e9af1387 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 2.0E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02905 132f4ce4efc7672807392056e9af1387 187 Gene3D G3DSA:1.10.357.10 1 187 4.0E-56 T 12-10-2018 AFR_00675 ff248dd5813ac8ab7069f216f45322e6 322 Gene3D G3DSA:3.40.50.10330 46 186 2.6E-5 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_00675 ff248dd5813ac8ab7069f216f45322e6 322 SUPERFAMILY SSF111331 61 303 5.45E-11 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_07890 377cfe33180d78bedce4c076a5be3f98 338 SUPERFAMILY SSF53807 50 319 3.77E-44 T 12-10-2018 AFR_07890 377cfe33180d78bedce4c076a5be3f98 338 Gene3D G3DSA:3.40.50.1980 179 323 6.4E-30 T 12-10-2018 AFR_07890 377cfe33180d78bedce4c076a5be3f98 338 Gene3D G3DSA:3.40.50.1980 37 177 3.4E-38 T 12-10-2018 AFR_07890 377cfe33180d78bedce4c076a5be3f98 338 Pfam PF01497 Periplasmic binding protein 96 291 7.8E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFR_32345 08e75bb4acf9840fdcd58aca75ff3af0 250 Pfam PF00293 NUDIX domain 25 142 3.2E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_32345 08e75bb4acf9840fdcd58aca75ff3af0 250 SUPERFAMILY SSF46785 164 238 5.44E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_32345 08e75bb4acf9840fdcd58aca75ff3af0 250 Gene3D G3DSA:3.90.79.10 10 152 5.1E-42 T 12-10-2018 AFR_32345 08e75bb4acf9840fdcd58aca75ff3af0 250 SUPERFAMILY SSF55811 19 161 1.18E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_32345 08e75bb4acf9840fdcd58aca75ff3af0 250 ProSitePatterns PS00893 Nudix box signature. 55 76 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_32345 08e75bb4acf9840fdcd58aca75ff3af0 250 Gene3D G3DSA:1.10.10.10 157 236 1.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10960 35b9e91f7b0c469b449f371830d63148 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 8.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10960 35b9e91f7b0c469b449f371830d63148 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 8.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10960 35b9e91f7b0c469b449f371830d63148 178 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_10960 35b9e91f7b0c469b449f371830d63148 178 SUPERFAMILY SSF46689 2 76 3.28E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_10960 35b9e91f7b0c469b449f371830d63148 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 3.0E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10960 35b9e91f7b0c469b449f371830d63148 178 Gene3D G3DSA:1.10.357.10 2 176 3.9E-28 T 12-10-2018 AFR_34430 712f3860ff1fff88431d7054a5453221 554 Gene3D G3DSA:3.30.70.270 393 553 1.2E-47 T 12-10-2018 AFR_34430 712f3860ff1fff88431d7054a5453221 554 SUPERFAMILY SSF55073 403 551 1.88E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_34430 712f3860ff1fff88431d7054a5453221 554 SMART SM00028 139 172 100.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 SMART SM00028 312 345 230.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 SMART SM00028 272 305 430.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 SMART SM00028 99 132 450.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 SMART SM00028 59 92 0.98 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 SUPERFAMILY SSF48452 42 256 6.96E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 Gene3D G3DSA:1.25.40.10 178 381 7.1E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 Gene3D G3DSA:1.25.40.10 2 177 2.2E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 Pfam PF00990 Diguanylate cyclase, GGDEF domain 399 549 4.8E-35 T 12-10-2018 IPR000160 GGDEF domain AFR_34430 712f3860ff1fff88431d7054a5453221 554 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 395 552 1.6E-39 T 12-10-2018 IPR000160 GGDEF domain AFR_34430 712f3860ff1fff88431d7054a5453221 554 SUPERFAMILY SSF48452 211 350 3.08E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_34430 712f3860ff1fff88431d7054a5453221 554 SMART SM00267 387 553 8.6E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_25150 f775969ee6665f9be91aa8c94f057f23 344 Gene3D G3DSA:3.50.50.60 1 343 1.8E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25150 f775969ee6665f9be91aa8c94f057f23 344 SUPERFAMILY SSF51905 132 341 5.18E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25150 f775969ee6665f9be91aa8c94f057f23 344 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 62 192 3.4E-11 T 12-10-2018 AFR_25150 f775969ee6665f9be91aa8c94f057f23 344 SUPERFAMILY SSF51905 1 195 6.26E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 Gene3D G3DSA:3.40.50.12780 438 857 1.2E-96 T 12-10-2018 AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 Gene3D G3DSA:3.30.559.30 199 412 2.8E-47 T 12-10-2018 AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 Pfam PF00550 Phosphopantetheine attachment site 1045 1108 3.7E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 Gene3D G3DSA:3.30.559.10 5 198 1.7E-51 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 SUPERFAMILY SSF52777 181 405 1.33E-34 T 12-10-2018 AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 SUPERFAMILY SSF56801 441 1056 7.72E-114 T 12-10-2018 AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 SUPERFAMILY SSF47336 1035 1109 3.53E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 SUPERFAMILY SSF52777 5 175 2.22E-34 T 12-10-2018 AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 Gene3D G3DSA:3.40.50.1820 1033 1111 1.2E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 Pfam PF00501 AMP-binding enzyme 448 864 3.6E-69 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 Pfam PF00668 Condensation domain 3 404 5.8E-47 T 12-10-2018 IPR001242 Condensation domain AFR_32570 f9fbc740b031d9d7ede9b0512806c8c8 1111 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_22265 f685628618ffe88879ff5fd07a185aef 361 Pfam PF00296 Luciferase-like monooxygenase 16 322 3.4E-64 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_22265 f685628618ffe88879ff5fd07a185aef 361 SUPERFAMILY SSF51679 14 355 5.45E-72 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22265 f685628618ffe88879ff5fd07a185aef 361 Gene3D G3DSA:3.20.20.30 11 357 6.8E-90 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_10570 5375bef68d231a73416bd8b97158053f 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 398 40.209 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 Gene3D G3DSA:3.40.50.1260 177 388 7.4E-142 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PIRSF PIRSF000724 1 398 1.7E-130 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 Pfam PF00162 Phosphoglycerate kinase 12 388 1.2E-143 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 198 217 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 317 342 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 175 197 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 113 128 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 35 57 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 145 167 6.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 Gene3D G3DSA:3.40.50.1260 12 396 7.4E-142 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_10570 5375bef68d231a73416bd8b97158053f 398 SUPERFAMILY SSF53748 3 397 1.65E-138 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_19580 ad0d019ee0cf53531ad0fe3a2b3acec0 729 Pfam PF00553 Cellulose binding domain 31 130 1.8E-28 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_19580 ad0d019ee0cf53531ad0fe3a2b3acec0 729 Gene3D G3DSA:2.60.40.10 153 243 1.6E-28 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_19580 ad0d019ee0cf53531ad0fe3a2b3acec0 729 SUPERFAMILY SSF69318 257 674 4.97E-10 T 12-10-2018 AFR_19580 ad0d019ee0cf53531ad0fe3a2b3acec0 729 Gene3D G3DSA:2.60.40.290 25 133 1.2E-32 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_19580 ad0d019ee0cf53531ad0fe3a2b3acec0 729 SUPERFAMILY SSF49384 27 132 9.77E-29 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_19580 ad0d019ee0cf53531ad0fe3a2b3acec0 729 SMART SM00637 31 130 2.3E-39 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_30755 0e85a12867407e4021277347fafd53e3 191 Pfam PF12840 Helix-turn-helix domain 11 64 1.7E-12 T 12-10-2018 AFR_30755 0e85a12867407e4021277347fafd53e3 191 Gene3D G3DSA:1.10.10.10 8 123 1.0E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30755 0e85a12867407e4021277347fafd53e3 191 SUPERFAMILY SSF46785 8 121 6.56E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30755 0e85a12867407e4021277347fafd53e3 191 SMART SM00418 11 109 9.1E-4 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_36675 f3b762b10c391ec623add5238b04bd40 294 SUPERFAMILY SSF53254 144 284 1.91E-11 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_36675 f3b762b10c391ec623add5238b04bd40 294 Gene3D G3DSA:3.90.79.10 5 136 4.3E-35 T 12-10-2018 AFR_36675 f3b762b10c391ec623add5238b04bd40 294 Gene3D G3DSA:3.40.50.1240 143 288 2.9E-19 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_36675 f3b762b10c391ec623add5238b04bd40 294 Pfam PF00293 NUDIX domain 6 130 5.2E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_36675 f3b762b10c391ec623add5238b04bd40 294 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 144 219 1.2E-5 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_36675 f3b762b10c391ec623add5238b04bd40 294 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_36675 f3b762b10c391ec623add5238b04bd40 294 SUPERFAMILY SSF55811 4 134 6.23E-27 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_10830 fbf2f952c0e6c67612d2cb288cfbbefa 117 Pfam PF12840 Helix-turn-helix domain 4 63 9.1E-13 T 12-10-2018 AFR_10830 fbf2f952c0e6c67612d2cb288cfbbefa 117 Gene3D G3DSA:1.10.10.10 1 109 2.1E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10830 fbf2f952c0e6c67612d2cb288cfbbefa 117 SUPERFAMILY SSF46785 3 100 8.74E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_10830 fbf2f952c0e6c67612d2cb288cfbbefa 117 SMART SM00418 2 84 2.0E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39505 86b49205a4f56b42e622958ad0fd0e99 475 Gene3D G3DSA:3.40.605.10 24 474 6.6E-176 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_39505 86b49205a4f56b42e622958ad0fd0e99 475 Pfam PF00171 Aldehyde dehydrogenase family 33 474 5.9E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_39505 86b49205a4f56b42e622958ad0fd0e99 475 Gene3D G3DSA:3.40.309.10 260 449 6.6E-176 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_39505 86b49205a4f56b42e622958ad0fd0e99 475 SUPERFAMILY SSF53720 17 474 8.64E-166 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_39505 86b49205a4f56b42e622958ad0fd0e99 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_15830 1fbf4fad0b9162999752827fd4789660 182 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 27 132 1.6E-9 T 12-10-2018 IPR018958 Knr4/Smi1-like domain AFR_15830 1fbf4fad0b9162999752827fd4789660 182 Gene3D G3DSA:3.40.1580.10 18 156 2.2E-8 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily AFR_15830 1fbf4fad0b9162999752827fd4789660 182 SMART SM00860 27 147 6.3E-7 T 12-10-2018 IPR018958 Knr4/Smi1-like domain AFR_15830 1fbf4fad0b9162999752827fd4789660 182 SUPERFAMILY SSF160631 24 135 5.1E-15 T 12-10-2018 AFR_37205 aa72afb894ee7e2de4191a5125cc2412 316 SMART SM00382 48 192 2.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37205 aa72afb894ee7e2de4191a5125cc2412 316 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 16 313 3.2E-106 T 12-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_37205 aa72afb894ee7e2de4191a5125cc2412 316 SUPERFAMILY SSF52540 2 313 2.56E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37205 aa72afb894ee7e2de4191a5125cc2412 316 Gene3D G3DSA:3.40.50.300 47 254 5.8E-87 T 12-10-2018 AFR_37205 aa72afb894ee7e2de4191a5125cc2412 316 Pfam PF03308 ArgK protein 22 280 1.1E-100 T 12-10-2018 AFR_18570 f0dbd1948cf3d460a6a3ccd78a168d29 339 Gene3D G3DSA:3.30.1780.10 21 338 4.8E-83 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 AFR_18570 f0dbd1948cf3d460a6a3ccd78a168d29 339 PIRSF PIRSF001439 16 328 7.4E-54 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFR_18570 f0dbd1948cf3d460a6a3ccd78a168d29 339 SUPERFAMILY SSF51735 1 331 5.82E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_18570 f0dbd1948cf3d460a6a3ccd78a168d29 339 Gene3D G3DSA:3.40.50.720 132 300 4.8E-83 T 12-10-2018 AFR_18570 f0dbd1948cf3d460a6a3ccd78a168d29 339 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 20 314 2.3E-54 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFR_23155 ad25453e28f3d0186f1c96e4b1e842f9 181 Gene3D G3DSA:1.10.10.10 1 89 6.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23155 ad25453e28f3d0186f1c96e4b1e842f9 181 Pfam PF10400 Virulence activator alpha C-term 92 177 1.2E-19 T 12-10-2018 IPR018309 Transcription regulator PadR, C-terminal AFR_23155 ad25453e28f3d0186f1c96e4b1e842f9 181 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 7.0E-13 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_23155 ad25453e28f3d0186f1c96e4b1e842f9 181 SUPERFAMILY SSF46785 3 178 6.98E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24950 fbf88bb32848c3b53adaa0e2fe5ee053 341 Pfam PF00756 Putative esterase 139 333 2.7E-9 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFR_24950 fbf88bb32848c3b53adaa0e2fe5ee053 341 SUPERFAMILY SSF53474 105 337 5.85E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_24950 fbf88bb32848c3b53adaa0e2fe5ee053 341 Gene3D G3DSA:3.40.50.1820 95 340 6.0E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_10415 5c57616e90a012c5e488736f55ba8f61 303 Gene3D G3DSA:3.40.190.10 148 252 2.7E-60 T 12-10-2018 AFR_10415 5c57616e90a012c5e488736f55ba8f61 303 SUPERFAMILY SSF53850 14 287 1.86E-55 T 12-10-2018 AFR_10415 5c57616e90a012c5e488736f55ba8f61 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 287 1.7E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_10415 5c57616e90a012c5e488736f55ba8f61 303 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 88 101 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site AFR_10415 5c57616e90a012c5e488736f55ba8f61 303 Gene3D G3DSA:3.40.190.10 62 286 2.7E-60 T 12-10-2018 AFR_10415 5c57616e90a012c5e488736f55ba8f61 303 SMART SM00062 64 290 1.1E-43 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_01715 95561cd999f634c9da598fcf9f44ab9f 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 170 194 2.1E-33 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01715 95561cd999f634c9da598fcf9f44ab9f 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 330 349 2.1E-33 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01715 95561cd999f634c9da598fcf9f44ab9f 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 382 408 2.1E-33 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01715 95561cd999f634c9da598fcf9f44ab9f 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 140 159 2.1E-33 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01715 95561cd999f634c9da598fcf9f44ab9f 512 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 242 266 2.1E-33 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01715 95561cd999f634c9da598fcf9f44ab9f 512 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 494 9.6E-164 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01715 95561cd999f634c9da598fcf9f44ab9f 512 Pfam PF00361 Proton-conducting membrane transporter 134 423 4.1E-60 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_35795 16fa072c0ed67a677af10c6b03d3e7b7 156 Pfam PF13560 Helix-turn-helix domain 8 66 4.6E-10 T 12-10-2018 AFR_35795 16fa072c0ed67a677af10c6b03d3e7b7 156 Gene3D G3DSA:1.10.260.40 3 86 4.0E-15 T 12-10-2018 AFR_35795 16fa072c0ed67a677af10c6b03d3e7b7 156 SUPERFAMILY SSF47413 3 70 1.44E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_35795 16fa072c0ed67a677af10c6b03d3e7b7 156 SMART SM00530 11 66 1.4E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_12485 81e3c01a72f136699adee362c33f4513 545 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 413 514 4.4E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_12485 81e3c01a72f136699adee362c33f4513 545 SMART SM00387 409 517 1.7E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_12485 81e3c01a72f136699adee362c33f4513 545 SUPERFAMILY SSF55874 407 514 1.15E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12485 81e3c01a72f136699adee362c33f4513 545 Gene3D G3DSA:3.30.565.10 374 515 1.7E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12485 81e3c01a72f136699adee362c33f4513 545 Pfam PF08376 Nitrate and nitrite sensing 47 143 2.2E-8 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein AFR_08650 4c6b73e8fc2b53365e50ec591213b1af 314 PRINTS PR00412 Epoxide hydrolase signature 267 289 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08650 4c6b73e8fc2b53365e50ec591213b1af 314 PRINTS PR00412 Epoxide hydrolase signature 53 68 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08650 4c6b73e8fc2b53365e50ec591213b1af 314 PRINTS PR00412 Epoxide hydrolase signature 234 250 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08650 4c6b73e8fc2b53365e50ec591213b1af 314 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_08650 4c6b73e8fc2b53365e50ec591213b1af 314 SUPERFAMILY SSF53474 5 288 1.15E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_08650 4c6b73e8fc2b53365e50ec591213b1af 314 Gene3D G3DSA:3.40.50.1820 2 295 1.4E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_08650 4c6b73e8fc2b53365e50ec591213b1af 314 Pfam PF12697 Alpha/beta hydrolase family 29 285 2.0E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19470 e0488e96af09854ac0e856961745cf1a 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 7.9E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_19470 e0488e96af09854ac0e856961745cf1a 223 SMART SM00448 1 112 2.2E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19470 e0488e96af09854ac0e856961745cf1a 223 Gene3D G3DSA:1.10.10.10 122 219 8.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19470 e0488e96af09854ac0e856961745cf1a 223 SUPERFAMILY SSF52172 2 173 4.13E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_19470 e0488e96af09854ac0e856961745cf1a 223 Pfam PF00072 Response regulator receiver domain 3 112 2.6E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_19470 e0488e96af09854ac0e856961745cf1a 223 SMART SM00862 145 217 9.0E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_19470 e0488e96af09854ac0e856961745cf1a 223 Gene3D G3DSA:3.40.50.2300 1 121 2.8E-31 T 12-10-2018 AFR_14885 1e48018cc520089076d37002f260ea31 311 SUPERFAMILY SSF51735 12 260 1.99E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14885 1e48018cc520089076d37002f260ea31 311 Gene3D G3DSA:3.40.50.720 6 311 3.9E-72 T 12-10-2018 AFR_14885 1e48018cc520089076d37002f260ea31 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14885 1e48018cc520089076d37002f260ea31 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14885 1e48018cc520089076d37002f260ea31 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14885 1e48018cc520089076d37002f260ea31 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14885 1e48018cc520089076d37002f260ea31 311 Pfam PF00106 short chain dehydrogenase 15 215 8.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_27360 78c4d1da9fb8e08d1c4b007f3741f887 403 SUPERFAMILY SSF53850 34 402 2.88E-72 T 12-10-2018 AFR_27360 78c4d1da9fb8e08d1c4b007f3741f887 403 Gene3D G3DSA:3.40.190.10 145 398 1.3E-80 T 12-10-2018 AFR_27360 78c4d1da9fb8e08d1c4b007f3741f887 403 Pfam PF13416 Bacterial extracellular solute-binding protein 54 352 8.3E-41 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_27360 78c4d1da9fb8e08d1c4b007f3741f887 403 Gene3D G3DSA:3.40.190.10 59 365 1.3E-80 T 12-10-2018 AFR_33040 0998d8447663e1c2feb1887281ae26b3 368 SUPERFAMILY SSF55874 259 366 1.49E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33040 0998d8447663e1c2feb1887281ae26b3 368 Pfam PF07730 Histidine kinase 171 235 1.7E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_33040 0998d8447663e1c2feb1887281ae26b3 368 Gene3D G3DSA:3.30.565.10 244 366 3.8E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21115 45df6bed4214ad1d877e0d6357719d48 528 SMART SM00331 312 526 4.2E-24 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_21115 45df6bed4214ad1d877e0d6357719d48 528 Gene3D G3DSA:3.30.450.20 39 162 5.1E-13 T 12-10-2018 AFR_21115 45df6bed4214ad1d877e0d6357719d48 528 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 338 526 1.9E-41 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_21115 45df6bed4214ad1d877e0d6357719d48 528 SUPERFAMILY SSF81606 329 525 1.44E-6 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_21115 45df6bed4214ad1d877e0d6357719d48 528 Gene3D G3DSA:3.60.40.10 278 526 6.7E-56 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 SUPERFAMILY SSF58014 65 130 1.15E-14 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 Pfam PF01025 GrpE 57 204 4.4E-30 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 Hamap MF_01151 Protein GrpE [grpE]. 5 205 16.412 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 SUPERFAMILY SSF51064 152 205 9.29E-17 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 ProSitePatterns PS01071 grpE protein signature. 160 203 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 Gene3D G3DSA:2.30.22.10 149 204 7.3E-19 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 Gene3D G3DSA:3.90.20.20 35 143 2.6E-14 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 PRINTS PR00773 GrpE protein signature 82 98 2.8E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 PRINTS PR00773 GrpE protein signature 157 172 2.8E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 PRINTS PR00773 GrpE protein signature 184 203 2.8E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFR_00525 5a5c34e5521da40ee3f36d8f1ef65428 207 PRINTS PR00773 GrpE protein signature 110 125 2.8E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFR_27820 8839e81f1f836dd740e42847303a7c99 687 Gene3D G3DSA:3.30.200.20 2 96 3.7E-26 T 12-10-2018 AFR_27820 8839e81f1f836dd740e42847303a7c99 687 Gene3D G3DSA:1.10.510.10 99 277 8.9E-43 T 12-10-2018 AFR_27820 8839e81f1f836dd740e42847303a7c99 687 Pfam PF00652 Ricin-type beta-trefoil lectin domain 567 684 9.4E-20 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_27820 8839e81f1f836dd740e42847303a7c99 687 SUPERFAMILY SSF50370 557 686 9.83E-27 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_27820 8839e81f1f836dd740e42847303a7c99 687 SMART SM00220 13 268 4.3E-58 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_27820 8839e81f1f836dd740e42847303a7c99 687 Gene3D G3DSA:2.80.10.50 562 686 8.9E-27 T 12-10-2018 AFR_27820 8839e81f1f836dd740e42847303a7c99 687 SUPERFAMILY SSF56112 10 318 1.35E-66 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_27820 8839e81f1f836dd740e42847303a7c99 687 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_27820 8839e81f1f836dd740e42847303a7c99 687 Pfam PF00069 Protein kinase domain 13 263 4.0E-44 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_27820 8839e81f1f836dd740e42847303a7c99 687 SMART SM00458 562 687 4.4E-14 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_00125 40eb3c761330a021312bcd8749cac734 190 Gene3D G3DSA:1.10.10.10 113 190 6.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00125 40eb3c761330a021312bcd8749cac734 190 Pfam PF08281 Sigma-70, region 4 135 185 8.9E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_00125 40eb3c761330a021312bcd8749cac734 190 SUPERFAMILY SSF88946 16 106 5.1E-16 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_00125 40eb3c761330a021312bcd8749cac734 190 Gene3D G3DSA:1.10.1740.10 18 100 1.5E-17 T 12-10-2018 AFR_00125 40eb3c761330a021312bcd8749cac734 190 SUPERFAMILY SSF88659 127 189 1.5E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_00125 40eb3c761330a021312bcd8749cac734 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 189 3.9E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_00125 40eb3c761330a021312bcd8749cac734 190 Pfam PF04542 Sigma-70 region 2 37 100 4.3E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_38495 00b74ae1436e5c15017bd656d3f5b484 179 Gene3D G3DSA:3.40.50.450 1 177 8.2E-65 T 12-10-2018 AFR_38495 00b74ae1436e5c15017bd656d3f5b484 179 Pfam PF03641 Possible lysine decarboxylase 46 174 8.9E-36 T 12-10-2018 IPR031100 LOG family AFR_38495 00b74ae1436e5c15017bd656d3f5b484 179 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 177 4.9E-54 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG AFR_38495 00b74ae1436e5c15017bd656d3f5b484 179 SUPERFAMILY SSF102405 3 177 1.98E-56 T 12-10-2018 AFR_12465 2e1d79cae30a6dfad7f0e916c0b4f968 652 Pfam PF01926 50S ribosome-binding GTPase 72 235 9.2E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_12465 2e1d79cae30a6dfad7f0e916c0b4f968 652 SUPERFAMILY SSF52540 54 272 2.0E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05990 5cd5ed00921da2eab028536ca0a2f500 378 Gene3D G3DSA:3.40.50.300 128 377 4.6E-96 T 12-10-2018 AFR_05990 5cd5ed00921da2eab028536ca0a2f500 378 Gene3D G3DSA:3.30.450.90 21 126 4.6E-31 T 12-10-2018 AFR_05990 5cd5ed00921da2eab028536ca0a2f500 378 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 28 370 4.2E-141 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 AFR_05990 5cd5ed00921da2eab028536ca0a2f500 378 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 219 233 - T 12-10-2018 IPR001482 Type II/IV secretion system protein AFR_05990 5cd5ed00921da2eab028536ca0a2f500 378 SUPERFAMILY SSF52540 27 364 3.23E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05990 5cd5ed00921da2eab028536ca0a2f500 378 Pfam PF00437 Type II/IV secretion system protein 139 289 3.6E-40 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFR_05990 5cd5ed00921da2eab028536ca0a2f500 378 SMART SM00382 148 273 2.3E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20825 9503f2fc680e532674d8c928ab101f78 163 Pfam PF01883 Iron-sulfur cluster assembly protein 10 70 4.4E-11 T 12-10-2018 IPR002744 MIP18 family-like AFR_20825 9503f2fc680e532674d8c928ab101f78 163 SUPERFAMILY SSF117916 8 93 2.06E-20 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFR_20825 9503f2fc680e532674d8c928ab101f78 163 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 11 163 2.2E-56 T 12-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit AFR_20825 9503f2fc680e532674d8c928ab101f78 163 Gene3D G3DSA:3.30.300.130 3 95 3.9E-21 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFR_12190 40b03b83178ca97cfcfdbfe6fdb244b7 148 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 21 99 1.8E-23 T 12-10-2018 IPR025161 Putative transposase IS4/IS5 family AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 Gene3D G3DSA:3.40.50.2300 1 126 5.3E-38 T 12-10-2018 AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 SMART SM00862 150 226 4.8E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 Pfam PF00072 Response regulator receiver domain 5 113 4.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 SUPERFAMILY SSF52172 2 125 7.83E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 Gene3D G3DSA:1.10.10.10 134 229 3.1E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 SMART SM00448 3 113 7.6E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 SUPERFAMILY SSF46894 135 225 5.67E-29 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_05765 a95166ac0ea0e382d53bb05e2cffd242 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 3.6E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_23340 8e68b96a434badb7d6185477b956c527 216 SUPERFAMILY SSF51735 1 206 1.98E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23340 8e68b96a434badb7d6185477b956c527 216 Gene3D G3DSA:3.40.50.720 1 214 2.7E-35 T 12-10-2018 AFR_23340 8e68b96a434badb7d6185477b956c527 216 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 206 7.1E-23 T 12-10-2018 AFR_23340 8e68b96a434badb7d6185477b956c527 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 168 1.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23340 8e68b96a434badb7d6185477b956c527 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 194 1.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23340 8e68b96a434badb7d6185477b956c527 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 57 68 1.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_23340 8e68b96a434badb7d6185477b956c527 216 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 106 122 1.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 Pfam PF00072 Response regulator receiver domain 3 108 6.7E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 SUPERFAMILY SSF52172 2 178 4.67E-16 T 12-10-2018 IPR011006 CheY-like superfamily AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 7.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 7.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 7.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 SMART SM00421 148 207 1.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 195 4.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 SMART SM00448 1 124 3.3E-5 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 Gene3D G3DSA:3.40.50.12740 1 208 1.4E-42 T 12-10-2018 AFR_16255 ebfd692c575790f6c0082d52b597ba38 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16365 4c819059a0e5a47d5e1bee11f7b21b91 537 SMART SM00637 444 534 2.3E-17 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_16365 4c819059a0e5a47d5e1bee11f7b21b91 537 SUPERFAMILY SSF53474 134 291 3.9E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16365 4c819059a0e5a47d5e1bee11f7b21b91 537 Gene3D G3DSA:2.60.40.290 439 537 1.7E-18 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_16365 4c819059a0e5a47d5e1bee11f7b21b91 537 Pfam PF00553 Cellulose binding domain 445 531 2.1E-14 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_16365 4c819059a0e5a47d5e1bee11f7b21b91 537 Gene3D G3DSA:3.40.50.1820 47 421 3.9E-104 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16365 4c819059a0e5a47d5e1bee11f7b21b91 537 SUPERFAMILY SSF49384 438 534 2.65E-19 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 Pfam PF02785 Biotin carboxylase C-terminal domain 338 442 1.1E-33 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 SUPERFAMILY SSF52440 1 113 1.87E-44 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_00170 b3177cff79bd627fabf96f694e84e341 454 Gene3D G3DSA:3.30.470.130 1 449 1.7E-179 T 12-10-2018 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 320 6.8E-68 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 SMART SM00878 338 443 2.4E-48 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 SUPERFAMILY SSF56059 83 346 8.84E-65 T 12-10-2018 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 7.8E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFR_00170 b3177cff79bd627fabf96f694e84e341 454 SUPERFAMILY SSF51246 334 445 4.81E-36 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFR_25410 84211f94ae756b71602d0403fb094fcc 448 Gene3D G3DSA:3.40.190.10 50 403 1.6E-123 T 12-10-2018 AFR_25410 84211f94ae756b71602d0403fb094fcc 448 Gene3D G3DSA:3.40.190.10 148 430 1.6E-123 T 12-10-2018 AFR_25410 84211f94ae756b71602d0403fb094fcc 448 SUPERFAMILY SSF53850 31 439 9.97E-66 T 12-10-2018 AFR_25410 84211f94ae756b71602d0403fb094fcc 448 Pfam PF01547 Bacterial extracellular solute-binding protein 45 336 3.5E-42 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_28135 bfb83f40ec89eedfdee1916c492ef3cb 204 PRINTS PR00449 Transforming protein P21 ras signature 20 41 5.5E-6 T 12-10-2018 AFR_28135 bfb83f40ec89eedfdee1916c492ef3cb 204 PRINTS PR00449 Transforming protein P21 ras signature 78 100 5.5E-6 T 12-10-2018 AFR_28135 bfb83f40ec89eedfdee1916c492ef3cb 204 PRINTS PR00449 Transforming protein P21 ras signature 168 190 5.5E-6 T 12-10-2018 AFR_28135 bfb83f40ec89eedfdee1916c492ef3cb 204 Pfam PF03029 Conserved hypothetical ATP binding protein 24 159 1.0E-19 T 12-10-2018 IPR004130 GPN-loop GTPase AFR_28135 bfb83f40ec89eedfdee1916c492ef3cb 204 Gene3D G3DSA:3.40.50.300 17 196 2.8E-17 T 12-10-2018 AFR_28135 bfb83f40ec89eedfdee1916c492ef3cb 204 SUPERFAMILY SSF52540 19 200 1.34E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13505 571ed8b6c777b09214fc27ec49167d97 397 Pfam PF07690 Major Facilitator Superfamily 25 332 1.7E-33 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_13505 571ed8b6c777b09214fc27ec49167d97 397 Gene3D G3DSA:1.20.1250.20 19 387 2.2E-38 T 12-10-2018 AFR_13505 571ed8b6c777b09214fc27ec49167d97 397 SUPERFAMILY SSF103473 8 390 8.63E-48 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_17570 e6f90efd6004f644323bbfb08447d545 299 SUPERFAMILY SSF51569 2 290 5.13E-55 T 12-10-2018 AFR_17570 e6f90efd6004f644323bbfb08447d545 299 Pfam PF00682 HMGL-like 2 271 1.6E-31 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFR_17570 e6f90efd6004f644323bbfb08447d545 299 Gene3D G3DSA:3.20.20.70 1 291 1.9E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_23335 7e7d4e973afb0e4fff2e3398fdb798a6 429 Gene3D G3DSA:3.90.550.10 16 248 1.9E-49 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23335 7e7d4e973afb0e4fff2e3398fdb798a6 429 SUPERFAMILY SSF53448 14 251 7.59E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23335 7e7d4e973afb0e4fff2e3398fdb798a6 429 Pfam PF00535 Glycosyl transferase family 2 24 142 8.1E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_23335 7e7d4e973afb0e4fff2e3398fdb798a6 429 Pfam PF02709 N-terminal domain of galactosyltransferase 180 221 4.0E-6 T 12-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 AFR_28425 81404c5e64e5235e4994960b5a2ba53d 178 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 4 119 1.3E-19 T 12-10-2018 IPR018727 Protein of unknown function DUF2267 AFR_28425 81404c5e64e5235e4994960b5a2ba53d 178 Gene3D G3DSA:1.10.490.110 3 59 1.9E-7 T 12-10-2018 AFR_34580 e2047885f7518d5e1158a017dea29aba 281 Gene3D G3DSA:1.10.3720.10 81 279 3.9E-26 T 12-10-2018 IPR035906 MetI-like superfamily AFR_34580 e2047885f7518d5e1158a017dea29aba 281 SUPERFAMILY SSF161098 84 270 2.09E-30 T 12-10-2018 IPR035906 MetI-like superfamily AFR_34580 e2047885f7518d5e1158a017dea29aba 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 278 2.1E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 3.4E-41 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 1.0E-24 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 Gene3D G3DSA:3.40.50.2020 155 299 8.7E-107 T 12-10-2018 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 SMART SM01400 12 128 1.1E-61 T 12-10-2018 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 12 323 43.915 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 Gene3D G3DSA:3.40.50.2020 15 310 8.7E-107 T 12-10-2018 AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 SUPERFAMILY SSF53271 77 314 3.57E-59 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_39720 3d4ea90ba02276dbf885b72b4437a340 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 8.1E-111 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 Gene3D G3DSA:1.10.10.10 77 165 7.1E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 Pfam PF04542 Sigma-70 region 2 19 79 2.1E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 Gene3D G3DSA:1.25.40.10 206 401 6.2E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 SUPERFAMILY SSF88659 103 163 1.87E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 SUPERFAMILY SSF88946 15 81 5.1E-9 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 Gene3D G3DSA:1.10.1740.10 4 75 2.6E-5 T 12-10-2018 AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 Pfam PF08281 Sigma-70, region 4 110 161 2.1E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_15085 6f74d7484969f3dd1504d0389ce12e17 417 SUPERFAMILY SSF48452 311 400 3.29E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_24530 61c5ad6dcb32a3a7db3b7a6baa82a162 231 Pfam PF08445 FR47-like protein 131 212 3.0E-23 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_24530 61c5ad6dcb32a3a7db3b7a6baa82a162 231 Gene3D G3DSA:3.40.630.30 1 221 4.4E-63 T 12-10-2018 AFR_24530 61c5ad6dcb32a3a7db3b7a6baa82a162 231 SUPERFAMILY SSF55729 95 211 1.64E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40280 126ad5a47103b00d3630f382cdf9031d 215 Pfam PF01895 PhoU domain 122 203 4.2E-9 T 12-10-2018 IPR026022 PhoU domain AFR_40280 126ad5a47103b00d3630f382cdf9031d 215 Pfam PF01895 PhoU domain 17 102 2.4E-19 T 12-10-2018 IPR026022 PhoU domain AFR_40280 126ad5a47103b00d3630f382cdf9031d 215 Gene3D G3DSA:1.20.58.220 1 214 2.4E-58 T 12-10-2018 IPR038078 PhoU-like domain superfamily AFR_40280 126ad5a47103b00d3630f382cdf9031d 215 SUPERFAMILY SSF109755 2 212 9.52E-55 T 12-10-2018 AFR_40280 126ad5a47103b00d3630f382cdf9031d 215 PIRSF PIRSF003107 1 215 9.6E-51 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFR_40280 126ad5a47103b00d3630f382cdf9031d 215 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 1.6E-51 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFR_14330 2ae63e30c6a18634a9ff849741494853 422 SUPERFAMILY SSF50370 38 154 3.48E-35 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_14330 2ae63e30c6a18634a9ff849741494853 422 Gene3D G3DSA:3.20.20.80 250 421 3.0E-15 T 12-10-2018 AFR_14330 2ae63e30c6a18634a9ff849741494853 422 Pfam PF00652 Ricin-type beta-trefoil lectin domain 34 152 7.9E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_14330 2ae63e30c6a18634a9ff849741494853 422 Gene3D G3DSA:2.80.10.50 25 158 2.2E-39 T 12-10-2018 AFR_14330 2ae63e30c6a18634a9ff849741494853 422 SUPERFAMILY SSF51445 205 418 1.57E-24 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_14330 2ae63e30c6a18634a9ff849741494853 422 Pfam PF11790 Glycosyl hydrolase catalytic core 202 417 4.2E-54 T 12-10-2018 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain AFR_14330 2ae63e30c6a18634a9ff849741494853 422 SMART SM00458 33 155 1.1E-24 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_07085 4db42567f197ecbc1c5259cbb4c30085 307 SUPERFAMILY SSF54001 193 297 2.39E-31 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_07085 4db42567f197ecbc1c5259cbb4c30085 307 Gene3D G3DSA:3.90.1720.10 119 301 1.9E-41 T 12-10-2018 AFR_07085 4db42567f197ecbc1c5259cbb4c30085 307 Pfam PF00877 NlpC/P60 family 209 292 2.8E-20 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_29260 dc74edd7527f57fb55074fc9d653e52a 185 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 27 150 9.4E-14 T 12-10-2018 AFR_29260 dc74edd7527f57fb55074fc9d653e52a 185 SUPERFAMILY SSF54593 26 165 6.26E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_29260 dc74edd7527f57fb55074fc9d653e52a 185 Gene3D G3DSA:3.10.180.10 18 165 7.6E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_28125 442e54b7f1214a6fac5d53c99dde2062 141 SMART SM00960 13 103 2.5E-23 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_28125 442e54b7f1214a6fac5d53c99dde2062 141 Gene3D G3DSA:3.30.450.30 9 133 4.7E-35 T 12-10-2018 AFR_28125 442e54b7f1214a6fac5d53c99dde2062 141 Pfam PF03259 Roadblock/LC7 domain 13 103 5.2E-18 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_28125 442e54b7f1214a6fac5d53c99dde2062 141 SUPERFAMILY SSF103196 6 128 1.03E-27 T 12-10-2018 AFR_06350 10539d3adc9f8e2e27accd7db94bd152 321 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 38 56 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AFR_06350 10539d3adc9f8e2e27accd7db94bd152 321 Gene3D G3DSA:3.40.50.1100 8 300 1.3E-97 T 12-10-2018 AFR_06350 10539d3adc9f8e2e27accd7db94bd152 321 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 304 4.5E-104 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFR_06350 10539d3adc9f8e2e27accd7db94bd152 321 SUPERFAMILY SSF53686 3 302 7.86E-81 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_06350 10539d3adc9f8e2e27accd7db94bd152 321 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 3.8E-61 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_06350 10539d3adc9f8e2e27accd7db94bd152 321 Gene3D G3DSA:3.40.50.1100 45 164 1.3E-97 T 12-10-2018 AFR_24365 f93215744371a137570eb90f7b9041ef 180 SUPERFAMILY SSF46689 2 78 1.13E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_24365 f93215744371a137570eb90f7b9041ef 180 Gene3D G3DSA:1.10.357.10 1 175 1.5E-21 T 12-10-2018 AFR_24365 f93215744371a137570eb90f7b9041ef 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10870 442b083c5b87fe7bb2f24adc8188dd6e 210 Gene3D G3DSA:2.30.110.10 6 189 7.1E-43 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_10870 442b083c5b87fe7bb2f24adc8188dd6e 210 SUPERFAMILY SSF50475 9 185 4.36E-32 T 12-10-2018 AFR_10870 442b083c5b87fe7bb2f24adc8188dd6e 210 Pfam PF01613 Flavin reductase like domain 12 158 1.6E-11 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AFR_36585 9543c03c8622788235e7bc5817619f4a 604 SUPERFAMILY SSF101473 5 203 2.88E-35 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_36585 9543c03c8622788235e7bc5817619f4a 604 SMART SM01121 300 604 1.8E-97 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain AFR_36585 9543c03c8622788235e7bc5817619f4a 604 Pfam PF02734 DAK2 domain 35 200 6.3E-34 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_36585 9543c03c8622788235e7bc5817619f4a 604 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 12 604 2.0E-135 T 12-10-2018 IPR019986 DAK2 domain-containing protein YloV AFR_36585 9543c03c8622788235e7bc5817619f4a 604 Pfam PF13684 Dihydroxyacetone kinase family 300 604 3.7E-79 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain AFR_36585 9543c03c8622788235e7bc5817619f4a 604 SMART SM01120 35 201 2.0E-49 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_27415 ec76b0112752b0cb9bd5f55c5c310901 245 SUPERFAMILY SSF46689 144 195 1.16E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_27415 ec76b0112752b0cb9bd5f55c5c310901 245 SMART SM00342 161 243 4.6E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_27415 ec76b0112752b0cb9bd5f55c5c310901 245 SUPERFAMILY SSF46689 198 244 6.81E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_27415 ec76b0112752b0cb9bd5f55c5c310901 245 Gene3D G3DSA:1.10.10.60 146 245 9.2E-21 T 12-10-2018 AFR_27415 ec76b0112752b0cb9bd5f55c5c310901 245 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 198 239 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_27415 ec76b0112752b0cb9bd5f55c5c310901 245 Pfam PF12833 Helix-turn-helix domain 167 244 4.5E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_00160 78b23164020efd1e4a0514e866531df6 952 Gene3D G3DSA:1.25.40.10 710 888 3.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00160 78b23164020efd1e4a0514e866531df6 952 SUPERFAMILY SSF48452 631 822 3.79E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00160 78b23164020efd1e4a0514e866531df6 952 Gene3D G3DSA:1.25.40.10 439 595 1.0E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00160 78b23164020efd1e4a0514e866531df6 952 SUPERFAMILY SSF48452 520 672 1.59E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_00160 78b23164020efd1e4a0514e866531df6 952 Gene3D G3DSA:1.25.40.10 603 709 5.0E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_40420 1fedc4375b75f32611270874153536cf 115 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site AFR_40420 1fedc4375b75f32611270874153536cf 115 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 54 111 1.1E-5 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFR_40420 1fedc4375b75f32611270874153536cf 115 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 17 113 1.9E-17 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 AFR_40420 1fedc4375b75f32611270874153536cf 115 PIRSF PIRSF002889 3 115 4.2E-18 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 AFR_40420 1fedc4375b75f32611270874153536cf 115 Pfam PF00460 Flagella basal body rod protein 11 37 1.3E-7 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFR_42735 d8184404ba152d9cd0ba7db7aba794ee 157 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 1 146 6.5E-56 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42735 d8184404ba152d9cd0ba7db7aba794ee 157 Pfam PF01967 MoaC family 12 145 1.1E-47 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42735 d8184404ba152d9cd0ba7db7aba794ee 157 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 1 153 31.607 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42735 d8184404ba152d9cd0ba7db7aba794ee 157 SUPERFAMILY SSF55040 8 150 1.96E-51 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42735 d8184404ba152d9cd0ba7db7aba794ee 157 Gene3D G3DSA:3.30.70.640 9 156 6.0E-58 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 548 2.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 534 2.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 573 2.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 592 2.9E-19 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 SMART SM00387 483 595 2.6E-45 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 SUPERFAMILY SSF47384 357 439 1.9E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 Gene3D G3DSA:3.30.565.10 445 596 3.8E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 SMART SM00388 374 438 4.0E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 Pfam PF00512 His Kinase A (phospho-acceptor) domain 375 437 2.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 484 594 6.2E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 Gene3D G3DSA:1.10.287.130 322 433 2.7E-20 T 12-10-2018 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 Pfam PF00672 HAMP domain 324 367 6.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_29425 deb12a58fc88f9825327df3a0f7a882e 597 SUPERFAMILY SSF55874 427 593 6.16E-49 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 164 272 2.2E-15 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 465 579 4.2E-31 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 Gene3D G3DSA:1.20.140.10 289 454 7.7E-44 T 12-10-2018 AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 446 2.2E-22 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 SUPERFAMILY SSF56645 38 280 9.56E-47 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 Gene3D G3DSA:1.10.540.10 12 160 9.0E-9 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 SUPERFAMILY SSF47203 281 451 4.35E-41 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 8 36 4.8E-11 T 12-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria AFR_25185 d8ef922fb049a8b366f5bb18f1a01fac 583 Gene3D G3DSA:2.40.110.10 162 288 7.1E-27 T 12-10-2018 AFR_38310 10674c60efa6227a56098d2465666c25 342 Gene3D G3DSA:3.30.230.10 208 333 7.1E-18 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_38310 10674c60efa6227a56098d2465666c25 342 SUPERFAMILY SSF54211 231 327 5.31E-19 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_38310 10674c60efa6227a56098d2465666c25 342 Pfam PF13180 PDZ domain 136 200 1.6E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_38310 10674c60efa6227a56098d2465666c25 342 SUPERFAMILY SSF50156 135 234 1.84E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFR_38310 10674c60efa6227a56098d2465666c25 342 Gene3D G3DSA:2.30.42.10 105 207 6.7E-13 T 12-10-2018 AFR_38310 10674c60efa6227a56098d2465666c25 342 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 235 304 4.6E-7 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFR_01435 91b3e396469db9bb0ec40d92f2431719 374 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 40 323 1.6E-43 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_01435 91b3e396469db9bb0ec40d92f2431719 374 Gene3D G3DSA:3.40.50.1100 58 164 1.0E-65 T 12-10-2018 AFR_01435 91b3e396469db9bb0ec40d92f2431719 374 Gene3D G3DSA:3.40.50.1100 43 330 1.0E-65 T 12-10-2018 AFR_01435 91b3e396469db9bb0ec40d92f2431719 374 SUPERFAMILY SSF53686 31 343 4.45E-69 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_06885 8e340ff16d6cf5a7aaeedd1077bd5bc0 318 Pfam PF13280 WYL domain 142 312 8.8E-30 T 12-10-2018 IPR026881 WYL domain AFR_06885 8e340ff16d6cf5a7aaeedd1077bd5bc0 318 Pfam PF08279 HTH domain 7 62 6.9E-14 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_06885 8e340ff16d6cf5a7aaeedd1077bd5bc0 318 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFR_06885 8e340ff16d6cf5a7aaeedd1077bd5bc0 318 SUPERFAMILY SSF46785 5 60 3.24E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06885 8e340ff16d6cf5a7aaeedd1077bd5bc0 318 Gene3D G3DSA:1.10.10.10 3 65 8.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06885 8e340ff16d6cf5a7aaeedd1077bd5bc0 318 PIRSF PIRSF016838 1 317 1.2E-24 T 12-10-2018 IPR028349 Protein PafC AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 SUPERFAMILY SSF52540 905 1111 9.84E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 ProSitePatterns PS00211 ABC transporters family signature. 456 470 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 Pfam PF00664 ABC transporter transmembrane region 54 267 6.6E-20 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 SUPERFAMILY SSF90123 7 308 7.06E-45 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 SUPERFAMILY SSF52540 361 544 1.31E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 SMART SM00382 936 1118 4.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 SMART SM00382 366 534 7.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 600 1093 1.4E-127 T 12-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 Gene3D G3DSA:3.40.50.300 903 1120 2.1E-57 T 12-10-2018 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 SUPERFAMILY SSF90123 603 896 1.96E-17 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 Pfam PF00005 ABC transporter 362 487 1.0E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 Gene3D G3DSA:1.20.1560.10 6 310 2.5E-40 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 Gene3D G3DSA:1.20.1560.10 586 900 2.8E-12 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 Gene3D G3DSA:3.40.50.300 342 545 2.1E-43 T 12-10-2018 AFR_20135 bf292faae66b31b45c67b5f76c2ab3c2 1123 Pfam PF00005 ABC transporter 928 1063 6.0E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_32460 43a2c807317070f292270d48d20055e7 146 Pfam PF03259 Roadblock/LC7 domain 16 102 1.7E-15 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_32460 43a2c807317070f292270d48d20055e7 146 SMART SM00960 14 103 9.9E-13 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_32460 43a2c807317070f292270d48d20055e7 146 SUPERFAMILY SSF103196 6 129 5.76E-22 T 12-10-2018 AFR_32460 43a2c807317070f292270d48d20055e7 146 Gene3D G3DSA:3.30.450.30 11 131 1.4E-22 T 12-10-2018 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 Pfam PF00512 His Kinase A (phospho-acceptor) domain 191 266 1.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 5.7E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 402 5.7E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 421 5.7E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 5.7E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 422 1.7E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 SMART SM00387 312 424 4.5E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 SUPERFAMILY SSF55874 256 426 2.62E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 Gene3D G3DSA:3.30.565.10 272 425 1.4E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 SUPERFAMILY SSF47384 180 265 7.85E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 Gene3D G3DSA:1.10.287.130 181 268 1.6E-19 T 12-10-2018 AFR_40275 18e0fe446e5b4369e37fc0b70294383f 447 SMART SM00388 190 267 4.9E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_14010 37e155a4f6dc89da962597b2f69cbefe 185 Gene3D G3DSA:1.10.10.10 113 178 7.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14010 37e155a4f6dc89da962597b2f69cbefe 185 SUPERFAMILY SSF88659 112 173 6.76E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_14010 37e155a4f6dc89da962597b2f69cbefe 185 SUPERFAMILY SSF88946 2 98 3.14E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14010 37e155a4f6dc89da962597b2f69cbefe 185 Pfam PF04542 Sigma-70 region 2 25 90 8.6E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14010 37e155a4f6dc89da962597b2f69cbefe 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 171 1.1E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_14010 37e155a4f6dc89da962597b2f69cbefe 185 Pfam PF08281 Sigma-70, region 4 118 170 2.3E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_14010 37e155a4f6dc89da962597b2f69cbefe 185 Gene3D G3DSA:1.10.1740.10 2 86 1.0E-29 T 12-10-2018 AFR_06245 65690158bf1c43a3d760955a5d9b842d 648 Gene3D G3DSA:3.10.310.50 20 159 2.8E-32 T 12-10-2018 AFR_06245 65690158bf1c43a3d760955a5d9b842d 648 Pfam PF04536 TPM domain 34 147 2.2E-15 T 12-10-2018 IPR007621 TPM domain AFR_32605 45a0ec7c6c1aea372b7ea1fd7acef60c 472 SUPERFAMILY SSF53300 307 439 5.44E-7 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_27165 44a53abd59cb523c521da5958f92e825 587 Gene3D G3DSA:1.10.510.10 99 281 3.3E-43 T 12-10-2018 AFR_27165 44a53abd59cb523c521da5958f92e825 587 Pfam PF00069 Protein kinase domain 20 269 3.0E-44 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_27165 44a53abd59cb523c521da5958f92e825 587 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_27165 44a53abd59cb523c521da5958f92e825 587 Gene3D G3DSA:3.30.200.20 12 98 1.3E-17 T 12-10-2018 AFR_27165 44a53abd59cb523c521da5958f92e825 587 Gene3D G3DSA:2.60.120.560 426 581 9.2E-7 T 12-10-2018 AFR_27165 44a53abd59cb523c521da5958f92e825 587 SUPERFAMILY SSF56112 17 341 5.93E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_27165 44a53abd59cb523c521da5958f92e825 587 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 48 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_27165 44a53abd59cb523c521da5958f92e825 587 SMART SM00220 20 274 1.1E-47 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_31965 6919b8cd1a260d269a47f687e1a5cd49 412 Gene3D G3DSA:1.10.10.10 1 71 5.5E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31965 6919b8cd1a260d269a47f687e1a5cd49 412 ProSitePatterns PS01125 ROK family signature. 212 239 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_31965 6919b8cd1a260d269a47f687e1a5cd49 412 Gene3D G3DSA:3.30.420.40 83 375 4.7E-70 T 12-10-2018 AFR_31965 6919b8cd1a260d269a47f687e1a5cd49 412 SUPERFAMILY SSF53067 75 381 3.03E-47 T 12-10-2018 AFR_31965 6919b8cd1a260d269a47f687e1a5cd49 412 Gene3D G3DSA:3.30.420.40 202 365 4.7E-70 T 12-10-2018 AFR_31965 6919b8cd1a260d269a47f687e1a5cd49 412 SUPERFAMILY SSF46785 4 67 5.55E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31965 6919b8cd1a260d269a47f687e1a5cd49 412 Pfam PF00480 ROK family 78 377 2.3E-44 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_23275 81ebe0027a0d898bf70ac07e11c701f7 298 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 17 275 1.1E-65 T 12-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted AFR_23275 81ebe0027a0d898bf70ac07e11c701f7 298 SUPERFAMILY SSF51679 7 285 7.07E-63 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_23275 81ebe0027a0d898bf70ac07e11c701f7 298 Pfam PF00296 Luciferase-like monooxygenase 10 242 7.1E-49 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_23275 81ebe0027a0d898bf70ac07e11c701f7 298 Gene3D G3DSA:3.20.20.30 1 297 3.0E-69 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_38210 5255cfd3a55ea8b866356ade616fa615 648 Pfam PF02446 4-alpha-glucanotransferase 136 621 1.1E-102 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 AFR_38210 5255cfd3a55ea8b866356ade616fa615 648 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 98 637 9.1E-83 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 AFR_38210 5255cfd3a55ea8b866356ade616fa615 648 SUPERFAMILY SSF51445 131 633 1.34E-120 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_38210 5255cfd3a55ea8b866356ade616fa615 648 Gene3D G3DSA:3.20.20.80 128 636 6.8E-111 T 12-10-2018 AFR_37810 14a8047db28cffb791865dac13fc7dc9 114 SUPERFAMILY SSF46785 11 101 4.09E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_37810 14a8047db28cffb791865dac13fc7dc9 114 Pfam PF03551 Transcriptional regulator PadR-like family 13 86 6.5E-17 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_37810 14a8047db28cffb791865dac13fc7dc9 114 Gene3D G3DSA:1.10.10.10 6 105 4.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04690 408faf46e610d7fa706de03d30d1b61b 211 SUPERFAMILY SSF51391 5 209 2.62E-50 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_04690 408faf46e610d7fa706de03d30d1b61b 211 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 211 24.094 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_04690 408faf46e610d7fa706de03d30d1b61b 211 Gene3D G3DSA:3.20.20.70 5 211 2.1E-55 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_04690 408faf46e610d7fa706de03d30d1b61b 211 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 206 1.1E-47 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_04690 408faf46e610d7fa706de03d30d1b61b 211 Pfam PF02581 Thiamine monophosphate synthase 8 193 2.8E-44 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_33580 5cb20899157d61d2b4689558d90a7715 247 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 34 118 1.6E-15 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_33580 5cb20899157d61d2b4689558d90a7715 247 Gene3D G3DSA:3.30.1360.20 32 127 5.1E-16 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_33580 5cb20899157d61d2b4689558d90a7715 247 SUPERFAMILY SSF54593 141 245 2.73E-8 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_33580 5cb20899157d61d2b4689558d90a7715 247 SUPERFAMILY SSF55248 31 120 2.88E-16 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_33580 5cb20899157d61d2b4689558d90a7715 247 Gene3D G3DSA:3.10.180.10 128 246 9.0E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21685 029e562650cda5880f399c58e57a4bb6 504 Pfam PF11329 Protein of unknown function (DUF3131) 29 171 9.1E-12 T 12-10-2018 IPR021478 Protein of unknown function DUF3131 AFR_21685 029e562650cda5880f399c58e57a4bb6 504 Pfam PF10091 Putative glucoamylase 282 461 7.8E-11 T 12-10-2018 IPR019282 Domain of unknown function DUF2329 AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 SUPERFAMILY SSF50447 3 105 1.62E-15 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 67 186 1.7E-28 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 Gene3D G3DSA:2.40.30.60 2 107 1.3E-20 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 Pfam PF05239 PRC-barrel domain 113 186 1.1E-7 T 12-10-2018 IPR027275 PRC-barrel domain AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 186 23.246 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 SUPERFAMILY SSF50346 117 186 5.89E-15 T 12-10-2018 IPR011033 PRC-barrel-like superfamily AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 Pfam PF01782 RimM N-terminal domain 4 105 4.9E-22 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 AFR_36320 9d3b1a301bc04ec732316b49463273d8 189 Gene3D G3DSA:2.30.30.240 112 189 1.9E-12 T 12-10-2018 AFR_23665 09482b95d54bbd8506658c7fe51df08e 68 Gene3D G3DSA:3.90.820.10 1 68 2.8E-35 T 12-10-2018 AFR_23665 09482b95d54bbd8506658c7fe51df08e 68 SMART SM00923 4 54 7.1E-32 T 12-10-2018 IPR005153 MbtH-like domain AFR_23665 09482b95d54bbd8506658c7fe51df08e 68 Pfam PF03621 MbtH-like protein 2 53 3.9E-28 T 12-10-2018 IPR005153 MbtH-like domain AFR_23665 09482b95d54bbd8506658c7fe51df08e 68 SUPERFAMILY SSF160582 3 66 3.27E-30 T 12-10-2018 IPR038020 MbtH-like domain superfamily AFR_29490 e478606e34d55a904881c49676af7e3f 524 SMART SM00231 31 159 0.0022 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_29490 e478606e34d55a904881c49676af7e3f 524 SUPERFAMILY SSF49785 36 157 1.21E-29 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29490 e478606e34d55a904881c49676af7e3f 524 Gene3D G3DSA:2.60.120.260 33 162 2.2E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29490 e478606e34d55a904881c49676af7e3f 524 Pfam PF00754 F5/8 type C domain 40 153 2.2E-26 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_29490 e478606e34d55a904881c49676af7e3f 524 Gene3D G3DSA:3.40.50.1110 292 524 5.2E-27 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 Gene3D G3DSA:3.40.50.12740 3 215 4.5E-70 T 12-10-2018 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 SMART SM00448 3 116 6.6E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 SMART SM00421 152 209 1.6E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 4.3E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 SUPERFAMILY SSF52172 2 135 1.15E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 SUPERFAMILY SSF46894 137 216 1.26E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_36095 5bbfca29447bd9b74feafcd31565e111 220 Pfam PF00072 Response regulator receiver domain 5 117 1.8E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40115 a55e6a59fbbe8335336e3c3a1aee0571 180 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 53 83 2.8E-9 T 12-10-2018 IPR019933 DivIVA domain AFR_40015 3a33fdb349c8c625947ccfeab34be97a 205 Pfam PF13828 Domain of unknown function (DUF4190) 121 187 5.7E-16 T 12-10-2018 IPR025241 Domain of unknown function DUF4190 AFR_20960 496e94630b482ba8d12c74e79a528c0f 351 Gene3D G3DSA:1.10.1780.10 201 350 2.0E-10 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_02940 b85010bd6718384c05c84bd0f478fbe3 239 Gene3D G3DSA:1.25.40.10 21 214 4.1E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02940 b85010bd6718384c05c84bd0f478fbe3 239 Pfam PF14559 Tetratricopeptide repeat 34 92 8.2E-6 T 12-10-2018 AFR_02940 b85010bd6718384c05c84bd0f478fbe3 239 SUPERFAMILY SSF48452 28 196 4.11E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_02940 b85010bd6718384c05c84bd0f478fbe3 239 Pfam PF13432 Tetratricopeptide repeat 136 194 0.014 T 12-10-2018 AFR_02940 b85010bd6718384c05c84bd0f478fbe3 239 SMART SM00028 57 90 0.29 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_02940 b85010bd6718384c05c84bd0f478fbe3 239 SMART SM00028 160 193 95.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_02940 b85010bd6718384c05c84bd0f478fbe3 239 SMART SM00028 91 124 120.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_22075 1569fe9781592a5b8ba7eea2e6baf788 412 Gene3D G3DSA:3.30.1870.10 62 135 6.0E-44 T 12-10-2018 AFR_22075 1569fe9781592a5b8ba7eea2e6baf788 412 Gene3D G3DSA:3.40.1660.10 9 359 6.0E-44 T 12-10-2018 AFR_22075 1569fe9781592a5b8ba7eea2e6baf788 412 Pfam PF05139 Erythromycin esterase 60 399 2.0E-43 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 AFR_22075 1569fe9781592a5b8ba7eea2e6baf788 412 PIRSF PIRSF000880 5 412 6.6E-110 T 12-10-2018 IPR016273 Erythromycin esterase, proteobacteria AFR_22075 1569fe9781592a5b8ba7eea2e6baf788 412 Gene3D G3DSA:1.20.1440.30 136 275 6.0E-44 T 12-10-2018 AFR_22075 1569fe9781592a5b8ba7eea2e6baf788 412 SUPERFAMILY SSF159501 9 399 6.8E-59 T 12-10-2018 AFR_09545 afbb6940de8e0fb8fddf2ee86b1eba8d 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 145 1.0E-10 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_09545 afbb6940de8e0fb8fddf2ee86b1eba8d 150 Gene3D G3DSA:3.30.530.20 4 150 1.9E-32 T 12-10-2018 IPR023393 START-like domain superfamily AFR_09545 afbb6940de8e0fb8fddf2ee86b1eba8d 150 SUPERFAMILY SSF55961 1 149 1.22E-29 T 12-10-2018 AFR_22695 92509276ce2093643fcbfd42f0841589 388 SUPERFAMILY SSF51905 4 381 3.01E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_22695 92509276ce2093643fcbfd42f0841589 388 Pfam PF01494 FAD binding domain 120 320 1.6E-14 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_22695 92509276ce2093643fcbfd42f0841589 388 Pfam PF01494 FAD binding domain 4 42 2.7E-5 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_22695 92509276ce2093643fcbfd42f0841589 388 Gene3D G3DSA:3.50.50.60 4 358 1.6E-106 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_22695 92509276ce2093643fcbfd42f0841589 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 8.9E-22 T 12-10-2018 AFR_22695 92509276ce2093643fcbfd42f0841589 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 8.9E-22 T 12-10-2018 AFR_22695 92509276ce2093643fcbfd42f0841589 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 8.9E-22 T 12-10-2018 AFR_22695 92509276ce2093643fcbfd42f0841589 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 8.9E-22 T 12-10-2018 AFR_01815 301906323462b272fc2193571e4bac2b 661 Gene3D G3DSA:3.40.50.12780 53 522 1.1E-105 T 12-10-2018 AFR_01815 301906323462b272fc2193571e4bac2b 661 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 10 654 50.529 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AFR_01815 301906323462b272fc2193571e4bac2b 661 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 30 82 1.1E-20 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFR_01815 301906323462b272fc2193571e4bac2b 661 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 25 651 3.0E-290 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AFR_01815 301906323462b272fc2193571e4bac2b 661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 259 270 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_01815 301906323462b272fc2193571e4bac2b 661 SUPERFAMILY SSF56801 30 650 8.24E-173 T 12-10-2018 AFR_01815 301906323462b272fc2193571e4bac2b 661 Pfam PF13193 AMP-binding enzyme C-terminal domain 538 620 2.4E-27 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_01815 301906323462b272fc2193571e4bac2b 661 Gene3D G3DSA:3.30.300.30 525 657 3.0E-30 T 12-10-2018 AFR_01815 301906323462b272fc2193571e4bac2b 661 Pfam PF00501 AMP-binding enzyme 88 529 5.5E-92 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_11845 dc266906af9500b057bdfa104f89c77d 104 SUPERFAMILY SSF103481 5 101 1.24E-16 T 12-10-2018 AFR_11845 dc266906af9500b057bdfa104f89c77d 104 Gene3D G3DSA:1.10.3730.20 1 104 3.9E-29 T 12-10-2018 AFR_11845 dc266906af9500b057bdfa104f89c77d 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.0E-25 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 AFR_09540 7348ba212783d412d41ff6ca123944a7 542 Gene3D G3DSA:3.30.565.10 401 525 6.8E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_09540 7348ba212783d412d41ff6ca123944a7 542 Gene3D G3DSA:3.30.450.40 164 328 1.7E-7 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_09540 7348ba212783d412d41ff6ca123944a7 542 Pfam PF07730 Histidine kinase 330 395 2.4E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_09540 7348ba212783d412d41ff6ca123944a7 542 SUPERFAMILY SSF55781 167 321 1.72E-6 T 12-10-2018 AFR_09540 7348ba212783d412d41ff6ca123944a7 542 SUPERFAMILY SSF55874 402 523 1.7E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_09540 7348ba212783d412d41ff6ca123944a7 542 SMART SM00387 435 527 9.2E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_38035 7d144757770927d5a535d1a4648b6f14 166 SUPERFAMILY SSF55729 5 151 3.09E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_38035 7d144757770927d5a535d1a4648b6f14 166 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 5.9E-12 T 12-10-2018 IPR000182 GNAT domain AFR_38035 7d144757770927d5a535d1a4648b6f14 166 Gene3D G3DSA:3.40.630.30 2 159 6.0E-42 T 12-10-2018 AFR_36100 ed7bae913e7e99d5ff529612246645f9 297 Pfam PF13732 Domain of unknown function (DUF4162) 214 295 1.5E-12 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 AFR_36100 ed7bae913e7e99d5ff529612246645f9 297 SMART SM00382 29 211 3.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_36100 ed7bae913e7e99d5ff529612246645f9 297 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_36100 ed7bae913e7e99d5ff529612246645f9 297 Gene3D G3DSA:3.40.50.300 2 232 5.2E-66 T 12-10-2018 AFR_36100 ed7bae913e7e99d5ff529612246645f9 297 SUPERFAMILY SSF52540 4 225 1.85E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36100 ed7bae913e7e99d5ff529612246645f9 297 Pfam PF00005 ABC transporter 20 160 9.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_12565 d95e339a63ea2a2137527c27aba34633 305 Gene3D G3DSA:3.40.50.300 2 226 3.3E-62 T 12-10-2018 AFR_12565 d95e339a63ea2a2137527c27aba34633 305 SUPERFAMILY SSF52540 4 221 3.65E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12565 d95e339a63ea2a2137527c27aba34633 305 Pfam PF00005 ABC transporter 20 157 4.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_12565 d95e339a63ea2a2137527c27aba34633 305 SMART SM00382 28 214 1.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_12565 d95e339a63ea2a2137527c27aba34633 305 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_42680 b695e43bf8690684000e721c377d7700 1053 SUPERFAMILY SSF52540 498 1031 1.4E-119 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42680 b695e43bf8690684000e721c377d7700 1053 Gene3D G3DSA:3.40.50.300 776 874 3.7E-11 T 12-10-2018 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Gene3D G3DSA:3.40.50.300 930 1028 5.6E-34 T 12-10-2018 AFR_42680 b695e43bf8690684000e721c377d7700 1053 SUPERFAMILY SSF89550 15 262 9.02E-15 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Pfam PF13361 UvrD-like helicase C-terminal domain 921 1008 2.9E-22 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Gene3D G3DSA:3.40.50.300 621 746 2.0E-39 T 12-10-2018 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Gene3D G3DSA:1.10.10.160 606 617 2.4E-37 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFR_42680 b695e43bf8690684000e721c377d7700 1053 Gene3D G3DSA:3.20.20.140 7 255 4.8E-11 T 12-10-2018 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Gene3D G3DSA:1.10.486.10 914 929 5.6E-34 T 12-10-2018 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Pfam PF13361 UvrD-like helicase C-terminal domain 726 866 3.0E-7 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Gene3D G3DSA:3.40.50.300 502 605 2.4E-37 T 12-10-2018 AFR_42680 b695e43bf8690684000e721c377d7700 1053 Pfam PF13245 AAA domain 506 705 2.1E-39 T 12-10-2018 AFR_26055 37761571d81cbf5cb3335c7aa59df7d3 226 PIRSF PIRSF006324 22 226 3.9E-47 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_26055 37761571d81cbf5cb3335c7aa59df7d3 226 Pfam PF01810 LysE type translocator 38 224 7.8E-38 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_41645 c50f6ab4e3a7268b51dba09929c195ef 51 Pfam PF13783 Domain of unknown function (DUF4177) 4 37 4.8E-6 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 AFR_32190 def117fd0417170ce9ceeb1793f6867b 214 SUPERFAMILY SSF51735 1 204 8.35E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_32190 def117fd0417170ce9ceeb1793f6867b 214 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 114 9.7E-5 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_32190 def117fd0417170ce9ceeb1793f6867b 214 Gene3D G3DSA:3.40.50.720 1 214 5.7E-38 T 12-10-2018 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 47 502 1.2E-137 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 696 742 3.2E-4 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 793 0.002 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 Gene3D G3DSA:3.90.199.10 47 516 2.3E-181 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 SUPERFAMILY SSF101904 537 799 1.57E-42 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFR_32025 5469c1227378e60a91264aae6ac59bda 840 Gene3D G3DSA:3.30.1360.40 250 363 2.3E-181 T 12-10-2018 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 SUPERFAMILY SSF56719 46 517 1.11E-150 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 SMART SM00434 26 495 3.8E-225 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_32025 5469c1227378e60a91264aae6ac59bda 840 Gene3D G3DSA:2.120.10.90 537 800 2.9E-49 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFR_32025 5469c1227378e60a91264aae6ac59bda 840 Gene3D G3DSA:1.10.268.10 400 488 2.3E-181 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFR_18090 42071a1d30ed021a7db83fcc4d22a0ab 462 Gene3D G3DSA:3.40.50.1820 53 250 2.2E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18090 42071a1d30ed021a7db83fcc4d22a0ab 462 Pfam PF05576 PS-10 peptidase S37 28 459 1.5E-149 T 12-10-2018 IPR008761 Peptidase S37, tripeptidyl aminopeptidase AFR_18090 42071a1d30ed021a7db83fcc4d22a0ab 462 SUPERFAMILY SSF53474 82 412 3.53E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_27635 86d8dc8f467f8c470d2f125300c38c77 432 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 385 1.9E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_16970 3c448ca79fd3ac904828438f65715fba 174 SMART SM00862 95 170 8.5E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_16970 3c448ca79fd3ac904828438f65715fba 174 Gene3D G3DSA:1.10.10.10 78 173 9.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16970 3c448ca79fd3ac904828438f65715fba 174 SUPERFAMILY SSF46894 81 171 8.79E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_16970 3c448ca79fd3ac904828438f65715fba 174 Pfam PF00486 Transcriptional regulatory protein, C terminal 96 170 5.6E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 Pfam PF03477 ATP cone domain 22 101 2.3E-12 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 Gene3D G3DSA:3.20.70.20 93 761 8.1E-245 T 12-10-2018 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 SUPERFAMILY SSF48168 27 229 3.01E-54 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 159 754 8.6E-214 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 156 227 1.2E-16 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 594 616 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 Pfam PF02867 Ribonucleotide reductase, barrel domain 231 750 1.9E-175 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 SUPERFAMILY SSF51998 230 755 5.8E-173 T 12-10-2018 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 PRINTS PR01183 Ribonucleotide reductase large chain signature 540 563 4.2E-51 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 PRINTS PR01183 Ribonucleotide reductase large chain signature 512 534 4.2E-51 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 PRINTS PR01183 Ribonucleotide reductase large chain signature 605 632 4.2E-51 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 PRINTS PR01183 Ribonucleotide reductase large chain signature 307 326 4.2E-51 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 PRINTS PR01183 Ribonucleotide reductase large chain signature 474 497 4.2E-51 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35675 33cde00e77a7aa42b31d0e7fc328cfa8 797 PRINTS PR01183 Ribonucleotide reductase large chain signature 437 448 4.2E-51 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 SUPERFAMILY SSF53850 92 296 2.29E-29 T 12-10-2018 AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 64 2.5E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 Pfam PF03466 LysR substrate binding domain 90 295 7.6E-32 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 SUPERFAMILY SSF46785 6 114 5.13E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 Gene3D G3DSA:1.10.10.10 4 92 8.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 Gene3D G3DSA:3.40.190.10 172 271 2.3E-35 T 12-10-2018 AFR_16355 b2fbe426d8ed6875a9086628bc318317 304 Gene3D G3DSA:3.40.190.10 94 279 2.3E-35 T 12-10-2018 AFR_25765 34a0050b4473405f160d97e348234efb 248 SUPERFAMILY SSF81296 29 170 2.52E-34 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_25765 34a0050b4473405f160d97e348234efb 248 Gene3D G3DSA:2.10.10.20 204 247 1.4E-20 T 12-10-2018 AFR_25765 34a0050b4473405f160d97e348234efb 248 SMART SM00495 202 248 1.1E-6 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_25765 34a0050b4473405f160d97e348234efb 248 SUPERFAMILY SSF51055 205 246 3.79E-14 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_25765 34a0050b4473405f160d97e348234efb 248 Gene3D G3DSA:2.70.50.50 29 170 1.4E-47 T 12-10-2018 AFR_25765 34a0050b4473405f160d97e348234efb 248 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 29 167 1.0E-17 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal AFR_30880 8b07399fe8630e7adf709dbc35a83c37 388 Pfam PF01168 Alanine racemase, N-terminal domain 51 241 5.0E-13 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFR_30880 8b07399fe8630e7adf709dbc35a83c37 388 Gene3D G3DSA:2.40.37.20 31 388 4.5E-124 T 12-10-2018 AFR_30880 8b07399fe8630e7adf709dbc35a83c37 388 Pfam PF14031 Putative serine dehydratase domain 294 373 4.9E-12 T 12-10-2018 IPR026956 D-serine dehydratase-like domain AFR_30880 8b07399fe8630e7adf709dbc35a83c37 388 Gene3D G3DSA:3.20.20.10 51 291 4.5E-124 T 12-10-2018 IPR029066 PLP-binding barrel AFR_30880 8b07399fe8630e7adf709dbc35a83c37 388 SUPERFAMILY SSF51419 51 248 3.27E-24 T 12-10-2018 IPR029066 PLP-binding barrel AFR_30880 8b07399fe8630e7adf709dbc35a83c37 388 SMART SM01119 294 375 2.0E-28 T 12-10-2018 IPR026956 D-serine dehydratase-like domain AFR_23160 e2e6b3d07760605bce6985ddf989893b 573 SUPERFAMILY SSF56645 16 238 6.54E-28 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_23160 e2e6b3d07760605bce6985ddf989893b 573 Gene3D G3DSA:2.40.110.10 136 247 2.1E-11 T 12-10-2018 AFR_23160 e2e6b3d07760605bce6985ddf989893b 573 Gene3D G3DSA:1.10.540.10 13 135 6.5E-5 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_23160 e2e6b3d07760605bce6985ddf989893b 573 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 392 6.1E-19 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_23160 e2e6b3d07760605bce6985ddf989893b 573 SUPERFAMILY SSF47203 244 399 7.09E-27 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_23160 e2e6b3d07760605bce6985ddf989893b 573 Gene3D G3DSA:1.20.140.10 248 397 4.7E-21 T 12-10-2018 AFR_27220 2decac42f762730f96b34ef2cae4c671 352 Pfam PF07730 Histidine kinase 167 231 5.4E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_27220 2decac42f762730f96b34ef2cae4c671 352 SUPERFAMILY SSF55874 237 346 3.33E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_27220 2decac42f762730f96b34ef2cae4c671 352 Gene3D G3DSA:3.30.565.10 232 347 3.8E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_02525 92cb150fce968445ef851997eb133b71 100 SUPERFAMILY SSF140453 3 97 1.44E-19 T 12-10-2018 IPR036689 ESAT-6-like superfamily AFR_02525 92cb150fce968445ef851997eb133b71 100 Pfam PF06013 Proteins of 100 residues with WXG 4 88 9.9E-11 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_02525 92cb150fce968445ef851997eb133b71 100 Gene3D G3DSA:1.10.287.1060 2 95 5.5E-18 T 12-10-2018 AFR_02525 92cb150fce968445ef851997eb133b71 100 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 2.3E-15 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_27850 19a82cef727b96942c6a8a887ff83b7f 441 SUPERFAMILY SSF110221 304 437 2.75E-42 T 12-10-2018 IPR036195 Alpha-L-arabinofuranosidase B, arabinose-binding domain superfamily GO:0046373|GO:0046556 AFR_27850 19a82cef727b96942c6a8a887ff83b7f 441 Gene3D G3DSA:2.115.10.20 62 274 7.1E-16 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_27850 19a82cef727b96942c6a8a887ff83b7f 441 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 304 436 6.7E-48 T 12-10-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 AFR_27850 19a82cef727b96942c6a8a887ff83b7f 441 Gene3D G3DSA:2.80.10.50 294 439 4.7E-51 T 12-10-2018 AFR_27850 19a82cef727b96942c6a8a887ff83b7f 441 Pfam PF04616 Glycosyl hydrolases family 43 71 198 1.5E-8 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_27850 19a82cef727b96942c6a8a887ff83b7f 441 SUPERFAMILY SSF75005 67 290 5.44E-25 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 224 524 1.8E-31 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 364 388 2.3E-34 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 225 247 2.3E-34 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 258 273 2.3E-34 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 516 535 2.3E-34 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 418 434 2.3E-34 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 456 477 2.3E-34 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 326 334 2.3E-34 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 Gene3D G3DSA:3.50.50.60 226 526 8.9E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 SUPERFAMILY SSF51905 211 533 3.65E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 5.6E-14 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 Gene3D G3DSA:2.60.120.10 6 141 5.2E-20 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 SUPERFAMILY SSF51206 13 133 2.49E-18 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 325 343 2.2E-22 T 12-10-2018 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 245 2.2E-22 T 12-10-2018 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 454 470 2.2E-22 T 12-10-2018 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 386 2.2E-22 T 12-10-2018 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 488 510 2.2E-22 T 12-10-2018 AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 Gene3D G3DSA:3.50.50.60 337 462 8.9E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_24215 b1d9748aa734e21bb33ba13e0ecf6978 558 SMART SM00100 10 127 3.5E-7 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFR_42255 e9a3829d2cff068fbe7557769bd6e1ab 197 SUPERFAMILY SSF54909 127 162 3.31E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_42255 e9a3829d2cff068fbe7557769bd6e1ab 197 Pfam PF03992 Antibiotic biosynthesis monooxygenase 97 161 1.5E-6 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_42255 e9a3829d2cff068fbe7557769bd6e1ab 197 Gene3D G3DSA:3.30.70.100 12 89 2.1E-8 T 12-10-2018 AFR_42255 e9a3829d2cff068fbe7557769bd6e1ab 197 Gene3D G3DSA:3.30.70.100 90 196 1.0E-26 T 12-10-2018 AFR_42255 e9a3829d2cff068fbe7557769bd6e1ab 197 SUPERFAMILY SSF54909 25 86 2.24E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_15190 cd87a1efe026bfd5dac68159606751ee 134 Gene3D G3DSA:3.10.180.10 1 121 2.3E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_15190 cd87a1efe026bfd5dac68159606751ee 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 3.7E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_15190 cd87a1efe026bfd5dac68159606751ee 134 SUPERFAMILY SSF54593 1 121 9.4E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_37310 78c40a91b097e1e29b4d23906baae738 428 Gene3D G3DSA:3.65.10.10 24 233 1.2E-152 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_37310 78c40a91b097e1e29b4d23906baae738 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 409 1.4E-91 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFR_37310 78c40a91b097e1e29b4d23906baae738 428 SUPERFAMILY SSF55205 5 418 1.57E-127 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFR_37310 78c40a91b097e1e29b4d23906baae738 428 Gene3D G3DSA:3.65.10.10 9 416 1.2E-152 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_37310 78c40a91b097e1e29b4d23906baae738 428 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 5 418 5.4E-155 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_37310 78c40a91b097e1e29b4d23906baae738 428 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 4 419 39.506 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_13695 6f03e02868a134a6b68b8254f7b0a41b 258 SUPERFAMILY SSF56112 10 221 5.69E-22 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_13695 6f03e02868a134a6b68b8254f7b0a41b 258 Gene3D G3DSA:3.30.200.20 12 106 2.7E-8 T 12-10-2018 AFR_13695 6f03e02868a134a6b68b8254f7b0a41b 258 Pfam PF01636 Phosphotransferase enzyme family 143 205 9.6E-6 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_13695 6f03e02868a134a6b68b8254f7b0a41b 258 Gene3D G3DSA:3.90.1200.10 107 246 9.7E-14 T 12-10-2018 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 10 1031 13.849 T 12-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 Gene3D G3DSA:3.90.740.10 210 405 1.5E-224 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 SUPERFAMILY SSF50677 213 401 1.36E-46 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 SUPERFAMILY SSF47323 664 890 2.8E-46 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 Gene3D G3DSA:1.10.730.10 651 825 1.9E-44 T 12-10-2018 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 25 643 1.9E-184 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 Gene3D G3DSA:3.40.50.620 22 635 1.5E-224 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 SUPERFAMILY SSF52374 11 656 9.12E-125 T 12-10-2018 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 Pfam PF08264 Anticodon-binding domain of tRNA 694 831 9.7E-26 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 568 577 8.1E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 232 255 8.1E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 528 541 8.1E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 8.1E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 52 63 8.1E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_07625 d2731090f75fb2cc7df1c44d162626fe 1038 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 843 2.1E-251 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFR_42535 c4665afc844c5ae4733f00ac00016626 248 Gene3D G3DSA:2.60.120.200 1 242 1.6E-34 T 12-10-2018 AFR_42535 c4665afc844c5ae4733f00ac00016626 248 SUPERFAMILY SSF49899 2 231 4.53E-28 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_42535 c4665afc844c5ae4733f00ac00016626 248 Pfam PF00722 Glycosyl hydrolases family 16 102 214 6.4E-11 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_24315 17713fe62a448873036fe6f24c9fff6d 390 Gene3D G3DSA:3.40.50.720 177 340 2.3E-109 T 12-10-2018 AFR_24315 17713fe62a448873036fe6f24c9fff6d 390 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 146 8.7E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_24315 17713fe62a448873036fe6f24c9fff6d 390 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_24315 17713fe62a448873036fe6f24c9fff6d 390 Gene3D G3DSA:3.90.180.10 10 375 2.3E-109 T 12-10-2018 AFR_24315 17713fe62a448873036fe6f24c9fff6d 390 SUPERFAMILY SSF50129 2 197 4.57E-53 T 12-10-2018 IPR011032 GroES-like superfamily AFR_24315 17713fe62a448873036fe6f24c9fff6d 390 Pfam PF00107 Zinc-binding dehydrogenase 196 265 1.9E-10 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_24315 17713fe62a448873036fe6f24c9fff6d 390 SUPERFAMILY SSF51735 164 350 4.81E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_39480 d0e0d708b45ddc66fcbcd2fbc366421a 323 Pfam PF08759 Glycosyltransferase GT-D fold 111 306 7.4E-33 T 12-10-2018 IPR014869 Glycosyltransferase GT-D fold AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 SUPERFAMILY SSF51735 3 247 5.26E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.8E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.8E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.8E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.8E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.8E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 Gene3D G3DSA:3.40.50.720 1 249 5.1E-54 T 12-10-2018 AFR_08810 fd33cdbcaabe9e53039c5366487e0ba3 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 2.8E-37 T 12-10-2018 AFR_23555 27b41fd452d3965310b892b2b0b77030 276 Pfam PF00561 alpha/beta hydrolase fold 25 132 5.5E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23555 27b41fd452d3965310b892b2b0b77030 276 Gene3D G3DSA:3.40.50.1820 11 275 2.5E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23555 27b41fd452d3965310b892b2b0b77030 276 SUPERFAMILY SSF53474 15 273 3.68E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23555 27b41fd452d3965310b892b2b0b77030 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 7.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23555 27b41fd452d3965310b892b2b0b77030 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 7.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23555 27b41fd452d3965310b892b2b0b77030 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 7.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_07895 6bcdd7b5d55bdcf314ee9d8dff2cc654 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 4.2E-47 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFR_07895 6bcdd7b5d55bdcf314ee9d8dff2cc654 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 2.0E-32 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFR_07895 6bcdd7b5d55bdcf314ee9d8dff2cc654 139 SUPERFAMILY SSF50692 1 116 1.86E-46 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFR_07895 6bcdd7b5d55bdcf314ee9d8dff2cc654 139 Gene3D G3DSA:2.40.40.20 1 122 4.3E-50 T 12-10-2018 AFR_07895 6bcdd7b5d55bdcf314ee9d8dff2cc654 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 129 68.388 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFR_07895 6bcdd7b5d55bdcf314ee9d8dff2cc654 139 PIRSF PIRSF006246 1 132 3.1E-51 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFR_07895 6bcdd7b5d55bdcf314ee9d8dff2cc654 139 Pfam PF02261 Aspartate decarboxylase 1 114 2.0E-49 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFR_19420 e40c47b4226420f3f908d33c302daaf0 212 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 80 184 7.7E-15 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_19420 e40c47b4226420f3f908d33c302daaf0 212 SUPERFAMILY SSF48498 80 186 1.34E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_19420 e40c47b4226420f3f908d33c302daaf0 212 SUPERFAMILY SSF46689 4 58 5.64E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19420 e40c47b4226420f3f908d33c302daaf0 212 Gene3D G3DSA:1.10.357.10 1 206 3.3E-37 T 12-10-2018 AFR_10985 286bcbe58c8826cb1456e1e82b70a26b 131 Pfam PF03061 Thioesterase superfamily 38 109 2.6E-6 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFR_10985 286bcbe58c8826cb1456e1e82b70a26b 131 Gene3D G3DSA:3.10.129.10 5 129 7.1E-38 T 12-10-2018 AFR_10985 286bcbe58c8826cb1456e1e82b70a26b 131 PIRSF PIRSF014972 4 131 2.2E-30 T 12-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase AFR_10985 286bcbe58c8826cb1456e1e82b70a26b 131 SUPERFAMILY SSF54637 5 127 2.2E-36 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 384 5.0E-117 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 12-10-2018 IPR018253 DnaJ domain, conserved site AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 SUPERFAMILY SSF49493 147 290 3.53E-16 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 SMART SM00271 9 67 3.9E-28 T 12-10-2018 IPR001623 DnaJ domain AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 Gene3D G3DSA:2.10.230.10 183 245 8.1E-19 T 12-10-2018 AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 SUPERFAMILY SSF46565 9 109 2.62E-28 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 Pfam PF00226 DnaJ domain 10 72 1.9E-25 T 12-10-2018 IPR001623 DnaJ domain AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 PRINTS PR00625 DnaJ domain signature 67 86 1.1E-22 T 12-10-2018 IPR001623 DnaJ domain AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 PRINTS PR00625 DnaJ domain signature 30 45 1.1E-22 T 12-10-2018 IPR001623 DnaJ domain AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 PRINTS PR00625 DnaJ domain signature 12 30 1.1E-22 T 12-10-2018 IPR001623 DnaJ domain AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 PRINTS PR00625 DnaJ domain signature 47 67 1.1E-22 T 12-10-2018 IPR001623 DnaJ domain AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 401 36.745 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 Pfam PF00684 DnaJ central domain 181 241 4.6E-13 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 Pfam PF01556 DnaJ C terminal domain 154 366 5.6E-35 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 SUPERFAMILY SSF57938 168 244 1.16E-17 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 Gene3D G3DSA:2.60.260.20 291 366 1.3E-25 T 12-10-2018 AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 SUPERFAMILY SSF49493 293 367 5.23E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFR_00530 67b36c8347ee615215fcae7c1390f3ac 401 Gene3D G3DSA:1.10.287.110 7 145 9.4E-29 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFR_12060 486906ecb6da94935b4fac09b1bf5635 364 Gene3D G3DSA:1.25.40.10 1 91 1.9E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_12060 486906ecb6da94935b4fac09b1bf5635 364 SUPERFAMILY SSF49265 265 343 3.73E-8 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_12060 486906ecb6da94935b4fac09b1bf5635 364 Gene3D G3DSA:2.60.40.10 263 358 1.1E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_09775 a8222d2bfaabac15ea53113a74009751 189 Pfam PF03596 Cadmium resistance transporter 13 188 1.8E-34 T 12-10-2018 IPR004676 Cadmium resistance transporter AFR_09745 a6375a1d1f59c8394093f154a8613751 165 SMART SM00347 30 129 8.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09745 a6375a1d1f59c8394093f154a8613751 165 Pfam PF12802 MarR family 36 93 7.0E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09745 a6375a1d1f59c8394093f154a8613751 165 SUPERFAMILY SSF46785 10 141 8.44E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_09745 a6375a1d1f59c8394093f154a8613751 165 Gene3D G3DSA:1.10.10.10 6 142 3.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_09745 a6375a1d1f59c8394093f154a8613751 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 4.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09745 a6375a1d1f59c8394093f154a8613751 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 4.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09745 a6375a1d1f59c8394093f154a8613751 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 4.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_09745 a6375a1d1f59c8394093f154a8613751 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 4.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23445 2aef6c1ad84243932dd535a08d8bc3b7 441 SUPERFAMILY SSF48113 68 422 6.0E-53 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFR_23445 2aef6c1ad84243932dd535a08d8bc3b7 441 Pfam PF03098 Animal haem peroxidase 143 260 1.2E-13 T 12-10-2018 IPR019791 Haem peroxidase, animal type AFR_23445 2aef6c1ad84243932dd535a08d8bc3b7 441 PRINTS PR00457 Animal haem peroxidase signature 69 84 2.2E-6 T 12-10-2018 IPR019791 Haem peroxidase, animal type AFR_23445 2aef6c1ad84243932dd535a08d8bc3b7 441 PRINTS PR00457 Animal haem peroxidase signature 186 212 2.2E-6 T 12-10-2018 IPR019791 Haem peroxidase, animal type AFR_23445 2aef6c1ad84243932dd535a08d8bc3b7 441 PRINTS PR00457 Animal haem peroxidase signature 242 252 2.2E-6 T 12-10-2018 IPR019791 Haem peroxidase, animal type AFR_23445 2aef6c1ad84243932dd535a08d8bc3b7 441 Gene3D G3DSA:1.10.640.10 123 345 1.2E-14 T 12-10-2018 IPR037120 Haem peroxidase domain superfamily, animal type AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 Pfam PF04023 FeoA domain 165 230 5.7E-9 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 3.6E-19 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 Gene3D G3DSA:2.30.30.90 162 231 2.0E-10 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 SUPERFAMILY SSF47979 65 136 1.83E-24 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 Gene3D G3DSA:1.10.10.10 1 72 4.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 SUPERFAMILY SSF50037 130 230 3.66E-21 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 SMART SM00899 158 231 8.9E-7 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 8.7E-27 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 Gene3D G3DSA:1.10.60.10 74 139 1.5E-26 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 SUPERFAMILY SSF46785 2 62 1.64E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_35435 4c6ee0ba5b740e863cbc8e16888b1360 232 SMART SM00529 26 125 2.2E-42 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFR_28470 15c612d8f9f76c03d2711be01743ca8b 130 Pfam PF13474 SnoaL-like domain 7 126 9.0E-14 T 12-10-2018 IPR037401 SnoaL-like domain AFR_28470 15c612d8f9f76c03d2711be01743ca8b 130 SUPERFAMILY SSF54427 1 128 2.2E-33 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_28470 15c612d8f9f76c03d2711be01743ca8b 130 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 3 128 6.1E-31 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 AFR_28470 15c612d8f9f76c03d2711be01743ca8b 130 Gene3D G3DSA:3.10.450.50 1 127 4.1E-40 T 12-10-2018 AFR_09370 cd35fb971cfc5309e51f8017fcf576be 327 SUPERFAMILY SSF53613 1 295 1.53E-50 T 12-10-2018 IPR029056 Ribokinase-like AFR_09370 cd35fb971cfc5309e51f8017fcf576be 327 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_09370 cd35fb971cfc5309e51f8017fcf576be 327 Gene3D G3DSA:3.40.1190.20 1 320 1.6E-74 T 12-10-2018 IPR029056 Ribokinase-like AFR_09370 cd35fb971cfc5309e51f8017fcf576be 327 Pfam PF00294 pfkB family carbohydrate kinase 30 295 3.4E-36 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_13625 0d420a702801af787ebf22ef22d1c005 295 Gene3D G3DSA:1.10.260.40 24 97 4.0E-6 T 12-10-2018 AFR_13625 0d420a702801af787ebf22ef22d1c005 295 Pfam PF13560 Helix-turn-helix domain 17 90 2.4E-11 T 12-10-2018 AFR_13625 0d420a702801af787ebf22ef22d1c005 295 Gene3D G3DSA:3.30.450.180 115 283 5.0E-15 T 12-10-2018 AFR_13625 0d420a702801af787ebf22ef22d1c005 295 SUPERFAMILY SSF47413 36 86 1.66E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_13625 0d420a702801af787ebf22ef22d1c005 295 SMART SM00530 10 87 1.6E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_28070 4396442d99323f0a4e8828ee7ee69c6d 371 Gene3D G3DSA:3.40.50.1820 30 226 1.2E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28070 4396442d99323f0a4e8828ee7ee69c6d 371 PIRSF PIRSF029171 19 371 7.2E-68 T 12-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 AFR_28070 4396442d99323f0a4e8828ee7ee69c6d 371 SUPERFAMILY SSF53474 42 368 3.16E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28070 4396442d99323f0a4e8828ee7ee69c6d 371 Pfam PF03583 Secretory lipase 118 371 2.1E-20 T 12-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 AFR_28070 4396442d99323f0a4e8828ee7ee69c6d 371 Gene3D G3DSA:3.40.50.1820 267 371 2.9E-10 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22570 bb80061fa3df4b80cb6ac52df8ee0153 100 SUPERFAMILY SSF46785 6 94 4.14E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_22570 bb80061fa3df4b80cb6ac52df8ee0153 100 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 4.3E-19 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_22570 bb80061fa3df4b80cb6ac52df8ee0153 100 Gene3D G3DSA:1.10.10.10 3 98 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13915 fce62db243076bfc0dcb8889b831bc48 345 Gene3D G3DSA:2.60.40.1120 147 230 6.9E-12 T 12-10-2018 AFR_13915 fce62db243076bfc0dcb8889b831bc48 345 SUPERFAMILY SSF49464 146 230 6.28E-10 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFR_13915 fce62db243076bfc0dcb8889b831bc48 345 Pfam PF13620 Carboxypeptidase regulatory-like domain 146 229 1.6E-13 T 12-10-2018 AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Gene3D G3DSA:2.70.98.10 34 260 1.0E-31 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Gene3D G3DSA:2.60.40.1180 506 594 3.5E-19 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Gene3D G3DSA:2.80.10.50 610 733 2.9E-41 T 12-10-2018 AFR_28485 a8bababf559c103dc3359752c221d6a6 735 SMART SM00458 607 735 4.3E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 505 593 1.2E-18 T 12-10-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Gene3D G3DSA:3.20.20.70 269 505 3.6E-76 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 42 269 3.0E-39 T 12-10-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain AFR_28485 a8bababf559c103dc3359752c221d6a6 735 SUPERFAMILY SSF51445 274 475 2.82E-20 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_28485 a8bababf559c103dc3359752c221d6a6 735 SUPERFAMILY SSF50370 611 732 1.31E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Pfam PF00652 Ricin-type beta-trefoil lectin domain 612 732 3.3E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_28485 a8bababf559c103dc3359752c221d6a6 735 Pfam PF10566 Glycoside hydrolase 97 276 503 1.9E-54 T 12-10-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain AFR_32385 af5785772825c4682f81965363fac1b4 199 Pfam PF00174 Oxidoreductase molybdopterin binding domain 35 179 3.0E-33 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFR_32385 af5785772825c4682f81965363fac1b4 199 Gene3D G3DSA:3.90.420.10 26 198 2.4E-41 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_32385 af5785772825c4682f81965363fac1b4 199 SUPERFAMILY SSF56524 16 197 5.36E-57 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_05595 7739f9c869266101535640304066c1fa 282 Gene3D G3DSA:1.10.260.40 6 102 8.6E-9 T 12-10-2018 AFR_05595 7739f9c869266101535640304066c1fa 282 SMART SM00530 10 83 1.8E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_05595 7739f9c869266101535640304066c1fa 282 Gene3D G3DSA:3.30.450.180 106 256 7.3E-8 T 12-10-2018 AFR_05595 7739f9c869266101535640304066c1fa 282 SUPERFAMILY SSF47413 31 83 1.18E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_05595 7739f9c869266101535640304066c1fa 282 Pfam PF13560 Helix-turn-helix domain 6 86 4.0E-16 T 12-10-2018 AFR_34480 ba6b54eebe20019ede742851a1596e52 126 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 64 123 5.1E-23 T 12-10-2018 AFR_34480 ba6b54eebe20019ede742851a1596e52 126 SUPERFAMILY SSF141694 4 57 2.62E-12 T 12-10-2018 AFR_34480 ba6b54eebe20019ede742851a1596e52 126 Pfam PF08922 Domain of unknown function (DUF1905) 3 55 4.6E-14 T 12-10-2018 IPR015018 Protein of unknown function DUF1905 AFR_34480 ba6b54eebe20019ede742851a1596e52 126 Gene3D G3DSA:2.40.30.100 1 58 4.9E-10 T 12-10-2018 IPR037079 AF2212/PG0164-like superfamily AFR_04150 52afe62c687d0d00f72c8adea7a40958 269 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 240 264 3.7 T 12-10-2018 IPR001330 PFTB repeat GO:0003824 AFR_04150 52afe62c687d0d00f72c8adea7a40958 269 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 82 102 0.46 T 12-10-2018 IPR001330 PFTB repeat GO:0003824 AFR_04150 52afe62c687d0d00f72c8adea7a40958 269 Gene3D G3DSA:1.50.10.20 34 201 9.5E-11 T 12-10-2018 AFR_04150 52afe62c687d0d00f72c8adea7a40958 269 SUPERFAMILY SSF48239 40 264 1.46E-20 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFR_36500 e34653744034194965e094732775d6a4 497 Pfam PF13692 Glycosyl transferases group 1 288 425 1.9E-14 T 12-10-2018 AFR_36500 e34653744034194965e094732775d6a4 497 Gene3D G3DSA:3.40.50.2000 287 445 2.7E-24 T 12-10-2018 AFR_36500 e34653744034194965e094732775d6a4 497 Gene3D G3DSA:3.40.50.2000 96 286 5.9E-6 T 12-10-2018 AFR_36500 e34653744034194965e094732775d6a4 497 Pfam PF11997 Domain of unknown function (DUF3492) 1 263 6.7E-18 T 12-10-2018 IPR022622 Domain of unknown function DUF3492 AFR_36500 e34653744034194965e094732775d6a4 497 SUPERFAMILY SSF53756 147 460 9.94E-43 T 12-10-2018 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 Gene3D G3DSA:3.30.70.141 2 140 2.4E-51 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 7 140 30.3 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 10 32 5.5E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 74 91 5.5E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 54 73 5.5E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 95 111 5.5E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 118 137 5.5E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 SUPERFAMILY SSF54919 7 139 3.54E-48 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 SMART SM00562 7 140 1.1E-63 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_07610 e7d89f23957796a51b1b14fc755e637b 140 Pfam PF00334 Nucleoside diphosphate kinase 8 139 8.7E-48 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_22090 779a0701c62d05fc551356d29afa281f 270 SUPERFAMILY SSF56281 26 246 2.84E-21 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_22090 779a0701c62d05fc551356d29afa281f 270 Pfam PF12706 Beta-lactamase superfamily domain 43 224 5.5E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_22090 779a0701c62d05fc551356d29afa281f 270 Gene3D G3DSA:3.60.15.10 14 268 2.1E-32 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_22470 2257ce9df01b8e33cda9abf29521ecbe 213 SMART SM00637 109 209 0.0016 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_22470 2257ce9df01b8e33cda9abf29521ecbe 213 Pfam PF00553 Cellulose binding domain 112 209 6.8E-7 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_22470 2257ce9df01b8e33cda9abf29521ecbe 213 SUPERFAMILY SSF49384 105 210 2.16E-7 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_22470 2257ce9df01b8e33cda9abf29521ecbe 213 Gene3D G3DSA:2.60.40.290 108 213 8.3E-16 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_29975 2c2bb99372ba92c52713aa9ec177c6f1 427 Pfam PF07730 Histidine kinase 168 204 1.6E-9 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_29975 2c2bb99372ba92c52713aa9ec177c6f1 427 SUPERFAMILY SSF55874 312 424 2.54E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_29975 2c2bb99372ba92c52713aa9ec177c6f1 427 SUPERFAMILY SSF81995 203 265 2.62E-6 T 12-10-2018 AFR_29975 2c2bb99372ba92c52713aa9ec177c6f1 427 Gene3D G3DSA:3.30.565.10 304 425 8.7E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 Gene3D G3DSA:3.30.160.270 450 562 2.5E-35 T 12-10-2018 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 SUPERFAMILY SSF51569 20 329 1.76E-99 T 12-10-2018 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 3 562 54.897 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 242 255 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 SMART SM00917 431 562 3.1E-33 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 SUPERFAMILY SSF110921 460 561 2.48E-35 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 2 561 3.9E-260 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 Pfam PF00682 HMGL-like 31 312 8.1E-77 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 Gene3D G3DSA:1.10.1220.20 394 447 1.1E-22 T 12-10-2018 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 SUPERFAMILY SSF89000 397 446 2.9E-14 T 12-10-2018 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 Gene3D G3DSA:3.20.20.70 10 385 2.5E-156 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 Pfam PF08502 LeuA allosteric (dimerisation) domain 431 561 6.2E-29 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_41755 5ded858817be3cd2e9a4695335c7580e 562 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.4E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 4.4E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 4.4E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 4.4E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 4.4E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 Gene3D G3DSA:3.40.50.720 1 223 3.7E-51 T 12-10-2018 AFR_19895 b83fdc83de883fa27603edab66d393df 227 SUPERFAMILY SSF51735 1 205 7.89E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19895 b83fdc83de883fa27603edab66d393df 227 Pfam PF00106 short chain dehydrogenase 7 186 4.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 1.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 1.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_19895 b83fdc83de883fa27603edab66d393df 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 1.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 SUPERFAMILY SSF55307 201 315 3.2E-44 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 168 9.4E-37 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 Pfam PF12327 FtsZ family, C-terminal domain 219 313 6.7E-36 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 377 37.981 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 PRINTS PR00423 Cell division protein FtsZ signature 186 208 2.7E-50 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 PRINTS PR00423 Cell division protein FtsZ signature 123 144 2.7E-50 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 PRINTS PR00423 Cell division protein FtsZ signature 95 115 2.7E-50 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 PRINTS PR00423 Cell division protein FtsZ signature 209 230 2.7E-50 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 SMART SM00865 204 321 7.4E-56 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 313 3.1E-127 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 SMART SM00864 10 202 2.2E-106 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 SUPERFAMILY SSF52490 9 205 4.97E-66 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 Gene3D G3DSA:3.40.50.1440 1 217 1.6E-80 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFR_10025 1d857afcc89f53b2cdb5d5f4c448fd50 378 Gene3D G3DSA:3.30.1330.20 218 322 1.1E-39 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AFR_31105 245d5d126c3ee019cf8d69c8028be219 384 SUPERFAMILY SSF53756 3 365 8.17E-70 T 12-10-2018 AFR_31105 245d5d126c3ee019cf8d69c8028be219 384 Pfam PF13692 Glycosyl transferases group 1 190 330 3.9E-24 T 12-10-2018 AFR_31105 245d5d126c3ee019cf8d69c8028be219 384 Gene3D G3DSA:3.40.50.2000 171 348 6.1E-107 T 12-10-2018 AFR_31105 245d5d126c3ee019cf8d69c8028be219 384 Pfam PF13439 Glycosyltransferase Family 4 14 172 6.9E-26 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_31105 245d5d126c3ee019cf8d69c8028be219 384 Gene3D G3DSA:3.40.50.2000 11 361 6.1E-107 T 12-10-2018 AFR_34370 c8d89ee1f59a64343a54478286819f5a 123 Pfam PF11533 Protein of unknown function (DUF3225) 1 120 3.2E-39 T 12-10-2018 IPR024507 Protein of unknown function DUF3225 AFR_34370 c8d89ee1f59a64343a54478286819f5a 123 Gene3D G3DSA:3.10.450.50 1 121 8.0E-39 T 12-10-2018 AFR_34370 c8d89ee1f59a64343a54478286819f5a 123 SUPERFAMILY SSF54427 1 121 8.79E-32 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 SUPERFAMILY SSF51735 4 234 1.39E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 Pfam PF00106 short chain dehydrogenase 3 199 2.2E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35585 7dbf1ff5af9848d9466c1fd2e7803afa 237 Gene3D G3DSA:3.40.50.720 2 236 4.1E-68 T 12-10-2018 AFR_19515 e1b8100f1b8bce58f1581c8f277c83ca 169 SUPERFAMILY SSF48498 68 164 1.33E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_19515 e1b8100f1b8bce58f1581c8f277c83ca 169 SUPERFAMILY SSF46689 2 71 9.75E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19515 e1b8100f1b8bce58f1581c8f277c83ca 169 Gene3D G3DSA:1.10.357.10 1 168 1.0E-33 T 12-10-2018 AFR_19515 e1b8100f1b8bce58f1581c8f277c83ca 169 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 45 6.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_27875 58ff229af8830e8e8e3b33bbf18402e3 372 Pfam PF13439 Glycosyltransferase Family 4 61 167 7.9E-9 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_27875 58ff229af8830e8e8e3b33bbf18402e3 372 Gene3D G3DSA:3.40.50.2000 38 356 3.7E-36 T 12-10-2018 AFR_27875 58ff229af8830e8e8e3b33bbf18402e3 372 Gene3D G3DSA:3.40.50.2000 165 341 3.7E-36 T 12-10-2018 AFR_27875 58ff229af8830e8e8e3b33bbf18402e3 372 SUPERFAMILY SSF53756 10 356 4.97E-39 T 12-10-2018 AFR_27875 58ff229af8830e8e8e3b33bbf18402e3 372 Pfam PF00534 Glycosyl transferases group 1 176 330 1.7E-16 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 Gene3D G3DSA:1.10.10.10 1 89 1.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.7E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 SUPERFAMILY SSF46785 1 87 1.78E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 Gene3D G3DSA:3.40.190.290 90 298 9.6E-45 T 12-10-2018 AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 SUPERFAMILY SSF53850 88 295 5.34E-43 T 12-10-2018 AFR_08985 1bec6717a3188f97ac67e7efce397bb9 303 Pfam PF03466 LysR substrate binding domain 87 293 1.4E-43 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 Gene3D G3DSA:3.50.50.60 155 273 1.3E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 451 8.2E-25 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 SUPERFAMILY SSF51905 3 334 9.07E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 Gene3D G3DSA:3.30.390.30 345 461 1.2E-29 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 324 2.7E-55 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.7E-30 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.7E-30 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 1.7E-30 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 1.7E-30 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.7E-30 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 SUPERFAMILY SSF55424 342 461 2.75E-30 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 Gene3D G3DSA:3.50.50.60 4 330 1.3E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 339 360 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 446 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 404 419 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 7.6E-56 T 12-10-2018 AFR_01160 994bee666b8bae0e21d70ce5eecacb2d 467 PIRSF PIRSF000350 1 464 4.6E-72 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_00135 0bc1c74ebbe238e95b63a7b4794b29f7 285 SUPERFAMILY SSF52540 9 217 3.55E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00135 0bc1c74ebbe238e95b63a7b4794b29f7 285 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_00135 0bc1c74ebbe238e95b63a7b4794b29f7 285 Pfam PF00005 ABC transporter 19 164 1.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_00135 0bc1c74ebbe238e95b63a7b4794b29f7 285 SMART SM00382 27 220 1.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_00135 0bc1c74ebbe238e95b63a7b4794b29f7 285 Gene3D G3DSA:3.40.50.300 1 229 1.7E-62 T 12-10-2018 AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 SUPERFAMILY SSF52540 22 456 4.85E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 Gene3D G3DSA:1.20.1580.10 108 374 8.3E-153 T 12-10-2018 AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 Gene3D G3DSA:3.40.50.300 22 475 8.3E-153 T 12-10-2018 AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 Gene3D G3DSA:1.20.1580.10 581 619 3.8E-101 T 12-10-2018 AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 Gene3D G3DSA:3.40.50.300 499 788 3.8E-101 T 12-10-2018 AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 Gene3D G3DSA:1.10.8.280 188 296 8.3E-153 T 12-10-2018 AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 Pfam PF00005 ABC transporter 505 712 7.8E-12 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_24020 fffce69fa4c56f9bab1d1d71be305f31 794 SUPERFAMILY SSF52540 496 765 7.85E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19195 2d2e3770b8c4054193d2e6c10d4a4388 225 SUPERFAMILY SSF56037 54 204 2.54E-28 T 12-10-2018 AFR_19195 2d2e3770b8c4054193d2e6c10d4a4388 225 SMART SM00873 59 209 9.4E-12 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFR_19195 2d2e3770b8c4054193d2e6c10d4a4388 225 Pfam PF03483 B3/4 domain 60 192 2.1E-19 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFR_12765 57302e4dc991ef6e5dad5787ae7d6bf4 218 Pfam PF04909 Amidohydrolase 26 216 2.7E-19 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_12765 57302e4dc991ef6e5dad5787ae7d6bf4 218 SUPERFAMILY SSF51556 28 217 1.09E-37 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_12765 57302e4dc991ef6e5dad5787ae7d6bf4 218 Gene3D G3DSA:3.20.20.140 21 217 8.2E-48 T 12-10-2018 AFR_08330 8d51a4c0526ea4badcf70f912b690527 213 Gene3D G3DSA:1.20.1080.10 157 212 5.2E-6 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFR_08330 8d51a4c0526ea4badcf70f912b690527 213 Gene3D G3DSA:1.20.1080.10 1 156 1.6E-20 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFR_08330 8d51a4c0526ea4badcf70f912b690527 213 Pfam PF00230 Major intrinsic protein 18 151 2.3E-12 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_08330 8d51a4c0526ea4badcf70f912b690527 213 Pfam PF00230 Major intrinsic protein 156 206 3.7E-5 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_08330 8d51a4c0526ea4badcf70f912b690527 213 PRINTS PR00783 Major intrinsic protein family signature 115 133 3.7E-7 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_08330 8d51a4c0526ea4badcf70f912b690527 213 PRINTS PR00783 Major intrinsic protein family signature 30 54 3.7E-7 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_08330 8d51a4c0526ea4badcf70f912b690527 213 SUPERFAMILY SSF81338 2 207 9.68E-31 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.6E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.6E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 2.6E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 SUPERFAMILY SSF53474 4 272 1.13E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 Pfam PF12697 Alpha/beta hydrolase family 23 264 7.3E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 PRINTS PR00412 Epoxide hydrolase signature 27 45 9.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 PRINTS PR00412 Epoxide hydrolase signature 104 117 9.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 PRINTS PR00412 Epoxide hydrolase signature 47 62 9.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 PRINTS PR00412 Epoxide hydrolase signature 248 270 9.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_29315 5c0a1fdac5a1ce004ed67ff20538c4f8 277 Gene3D G3DSA:3.40.50.1820 2 275 1.5E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15245 6f623f64e3e2dd8e618febd5399d6a48 299 Pfam PF12833 Helix-turn-helix domain 210 284 4.7E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_15245 6f623f64e3e2dd8e618febd5399d6a48 299 Pfam PF06719 AraC-type transcriptional regulator N-terminus 21 174 1.4E-42 T 12-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal AFR_15245 6f623f64e3e2dd8e618febd5399d6a48 299 SUPERFAMILY SSF46689 187 237 1.07E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15245 6f623f64e3e2dd8e618febd5399d6a48 299 SUPERFAMILY SSF46689 239 288 1.61E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15245 6f623f64e3e2dd8e618febd5399d6a48 299 Gene3D G3DSA:1.10.10.60 187 290 2.7E-29 T 12-10-2018 AFR_15245 6f623f64e3e2dd8e618febd5399d6a48 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 240 282 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_15245 6f623f64e3e2dd8e618febd5399d6a48 299 SMART SM00342 203 286 3.1E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_05205 880a31f70b76410b1dcd0a0041eb58af 614 SUPERFAMILY SSF52540 317 490 1.88E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05205 880a31f70b76410b1dcd0a0041eb58af 614 Gene3D G3DSA:3.40.50.300 249 494 2.6E-37 T 12-10-2018 AFR_05205 880a31f70b76410b1dcd0a0041eb58af 614 Pfam PF13807 G-rich domain on putative tyrosine kinase 207 255 1.2E-6 T 12-10-2018 IPR032807 Tyrosine kinase, G-rich domain AFR_01810 2475367066f12597312e64cdfc02bc87 794 SUPERFAMILY SSF55486 263 393 3.93E-11 T 12-10-2018 AFR_01810 2475367066f12597312e64cdfc02bc87 794 Pfam PF05547 Immune inhibitor A peptidase M6 106 783 4.0E-175 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_01810 2475367066f12597312e64cdfc02bc87 794 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 169 449 3.8E-68 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_01810 2475367066f12597312e64cdfc02bc87 794 PIRSF PIRSF007519 147 793 6.0E-163 T 12-10-2018 IPR012300 Peptidase M6, InhA AFR_01810 2475367066f12597312e64cdfc02bc87 794 PIRSF PIRSF007519 36 142 5.8 T 12-10-2018 IPR012300 Peptidase M6, InhA AFR_22240 26020bc6b26e763f4c0bbda6d7a6680a 242 SUPERFAMILY SSF53474 10 227 2.7E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22240 26020bc6b26e763f4c0bbda6d7a6680a 242 Gene3D G3DSA:3.40.50.1820 8 227 1.1E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22215 360708ef305cb97ac2eb23f969fc9349 138 SUPERFAMILY SSF46785 17 127 1.6E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_22215 360708ef305cb97ac2eb23f969fc9349 138 Gene3D G3DSA:1.10.10.10 6 137 8.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22215 360708ef305cb97ac2eb23f969fc9349 138 SMART SM00347 22 123 9.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_22215 360708ef305cb97ac2eb23f969fc9349 138 Pfam PF12802 MarR family 28 86 6.7E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_23240 9d13695b1883ad0d8ef8f2160e4582fb 210 Pfam PF12158 Protein of unknown function (DUF3592) 77 194 1.5E-6 T 12-10-2018 IPR021994 Protein of unknown function DUF3592 AFR_13495 42a9021e473256be1654bff3330012e0 300 Gene3D G3DSA:3.40.190.290 92 288 5.3E-34 T 12-10-2018 AFR_13495 42a9021e473256be1654bff3330012e0 300 SUPERFAMILY SSF53850 91 287 8.22E-33 T 12-10-2018 AFR_13495 42a9021e473256be1654bff3330012e0 300 SUPERFAMILY SSF46785 3 110 1.21E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13495 42a9021e473256be1654bff3330012e0 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13495 42a9021e473256be1654bff3330012e0 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13495 42a9021e473256be1654bff3330012e0 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13495 42a9021e473256be1654bff3330012e0 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.0E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_13495 42a9021e473256be1654bff3330012e0 300 Pfam PF03466 LysR substrate binding domain 88 286 3.5E-34 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_13495 42a9021e473256be1654bff3330012e0 300 Gene3D G3DSA:1.10.10.10 3 88 2.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20065 6f4d0ad797c64c7e1b0f4e172dcd3def 288 Gene3D G3DSA:1.10.287.700 46 153 8.5E-7 T 12-10-2018 AFR_31560 d9479385008f09de25188aa5da686311 240 Gene3D G3DSA:3.60.40.10 2 237 1.2E-65 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31560 d9479385008f09de25188aa5da686311 240 Pfam PF13672 Protein phosphatase 2C 15 198 2.8E-16 T 12-10-2018 AFR_31560 d9479385008f09de25188aa5da686311 240 SMART SM00332 2 234 1.4E-20 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31560 d9479385008f09de25188aa5da686311 240 SUPERFAMILY SSF81606 4 237 1.24E-67 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31560 d9479385008f09de25188aa5da686311 240 SMART SM00331 11 236 1.8E-30 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_12040 9b0485d9e14ae1c21e6d851825cca6c8 910 Gene3D G3DSA:3.10.620.30 380 544 5.1E-11 T 12-10-2018 AFR_12040 9b0485d9e14ae1c21e6d851825cca6c8 910 SMART SM00460 468 534 2.4E-7 T 12-10-2018 IPR002931 Transglutaminase-like AFR_12040 9b0485d9e14ae1c21e6d851825cca6c8 910 Pfam PF01841 Transglutaminase-like superfamily 417 532 1.0E-17 T 12-10-2018 IPR002931 Transglutaminase-like AFR_12040 9b0485d9e14ae1c21e6d851825cca6c8 910 SUPERFAMILY SSF54001 414 553 5.4E-17 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_30855 dba8e56a0e8adbf74eaeb1bf35fef1e9 165 SUPERFAMILY SSF48452 26 136 1.85E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_30855 dba8e56a0e8adbf74eaeb1bf35fef1e9 165 Pfam PF12688 Tetratrico peptide repeat 32 150 7.3E-52 T 12-10-2018 AFR_30855 dba8e56a0e8adbf74eaeb1bf35fef1e9 165 Gene3D G3DSA:1.25.40.10 43 148 6.6E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_24125 7419036b57b01ce32d0f60e77dee4a0d 185 Gene3D G3DSA:3.40.630.30 2 160 2.7E-8 T 12-10-2018 AFR_24125 7419036b57b01ce32d0f60e77dee4a0d 185 SUPERFAMILY SSF55729 13 148 3.23E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 SUPERFAMILY SSF49503 193 314 2.63E-33 T 12-10-2018 IPR008972 Cupredoxin AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 Gene3D G3DSA:2.60.40.420 471 598 2.1E-33 T 12-10-2018 IPR008972 Cupredoxin AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 Pfam PF07731 Multicopper oxidase 491 590 3.2E-22 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 ProSitePatterns PS00080 Multicopper oxidases signature 2. 573 584 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 Gene3D G3DSA:2.60.40.420 312 438 3.6E-12 T 12-10-2018 IPR008972 Cupredoxin AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 SUPERFAMILY SSF49503 458 591 3.42E-31 T 12-10-2018 IPR008972 Cupredoxin AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 SUPERFAMILY SSF49503 322 413 4.37E-7 T 12-10-2018 IPR008972 Cupredoxin AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 Gene3D G3DSA:2.60.40.420 167 311 1.4E-39 T 12-10-2018 IPR008972 Cupredoxin AFR_14710 51973dec486ee0ed95f8976c73b41a04 604 Pfam PF07732 Multicopper oxidase 201 313 1.4E-31 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 AFR_24955 f9539061e92102c2ae44918dae86e78e 116 Gene3D G3DSA:3.30.750.24 3 111 2.4E-26 T 12-10-2018 IPR036513 STAS domain superfamily AFR_24955 f9539061e92102c2ae44918dae86e78e 116 SUPERFAMILY SSF52091 9 106 5.1E-23 T 12-10-2018 IPR036513 STAS domain superfamily AFR_24955 f9539061e92102c2ae44918dae86e78e 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 7 107 3.1E-22 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_24955 f9539061e92102c2ae44918dae86e78e 116 Pfam PF01740 STAS domain 11 103 1.0E-16 T 12-10-2018 IPR002645 STAS domain AFR_32760 7e253cfab541a069eaadd7051cac9962 245 SUPERFAMILY SSF161098 41 225 7.46E-33 T 12-10-2018 IPR035906 MetI-like superfamily AFR_32760 7e253cfab541a069eaadd7051cac9962 245 Gene3D G3DSA:1.10.3720.10 42 234 8.4E-25 T 12-10-2018 IPR035906 MetI-like superfamily AFR_32760 7e253cfab541a069eaadd7051cac9962 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 233 8.6E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_04745 9d4ebb462e5749d3978a0493ad61f85b 335 Pfam PF09084 NMT1/THI5 like 49 260 5.3E-41 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_04745 9d4ebb462e5749d3978a0493ad61f85b 335 SUPERFAMILY SSF53850 46 267 3.7E-31 T 12-10-2018 AFR_04745 9d4ebb462e5749d3978a0493ad61f85b 335 Gene3D G3DSA:3.40.190.10 48 310 2.6E-54 T 12-10-2018 AFR_04745 9d4ebb462e5749d3978a0493ad61f85b 335 Gene3D G3DSA:3.40.190.10 118 221 2.6E-54 T 12-10-2018 AFR_17060 81cee068bb6d44688815997ac4613108 556 Gene3D G3DSA:2.80.10.50 87 213 6.0E-18 T 12-10-2018 AFR_17060 81cee068bb6d44688815997ac4613108 556 SMART SM00458 27 168 1.4E-8 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17060 81cee068bb6d44688815997ac4613108 556 SUPERFAMILY SSF89372 299 500 7.98E-13 T 12-10-2018 AFR_17060 81cee068bb6d44688815997ac4613108 556 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 111 172 2.5E-7 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17060 81cee068bb6d44688815997ac4613108 556 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 29 104 1.2E-19 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17060 81cee068bb6d44688815997ac4613108 556 Gene3D G3DSA:2.80.10.50 24 86 3.0E-13 T 12-10-2018 AFR_17060 81cee068bb6d44688815997ac4613108 556 SUPERFAMILY SSF50370 27 167 2.48E-36 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 Gene3D G3DSA:1.10.10.60 3 52 3.8E-18 T 12-10-2018 AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 183 4.5E-14 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 SUPERFAMILY SSF48498 76 188 3.11E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 5.3E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 Gene3D G3DSA:1.10.357.10 53 191 4.3E-17 T 12-10-2018 AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02380 ce4a496da1e719b485f60b6333b59dd3 204 SUPERFAMILY SSF46689 5 68 7.98E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_22005 b9216ec619cdde744b2c35a545aa1a3e 259 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 21 231 5.3E-52 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related AFR_00435 5c5a3f4d504a377a4fe0ec22f9582927 171 Gene3D G3DSA:3.40.50.1240 1 169 9.8E-40 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_00435 5c5a3f4d504a377a4fe0ec22f9582927 171 SMART SM00855 5 123 1.1E-6 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_00435 5c5a3f4d504a377a4fe0ec22f9582927 171 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 69 6.1E-7 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_00435 5c5a3f4d504a377a4fe0ec22f9582927 171 SUPERFAMILY SSF53254 1 133 4.07E-17 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_24440 5ecd38a75a5112cf9f1eb739270826eb 419 SUPERFAMILY SSF88659 107 169 1.16E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_24440 5ecd38a75a5112cf9f1eb739270826eb 419 Gene3D G3DSA:1.10.10.10 120 171 5.2E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24440 5ecd38a75a5112cf9f1eb739270826eb 419 SUPERFAMILY SSF88946 10 77 4.71E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24440 5ecd38a75a5112cf9f1eb739270826eb 419 Pfam PF08281 Sigma-70, region 4 119 167 3.8E-7 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_24440 5ecd38a75a5112cf9f1eb739270826eb 419 Pfam PF04542 Sigma-70 region 2 16 80 4.6E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24440 5ecd38a75a5112cf9f1eb739270826eb 419 Gene3D G3DSA:1.10.1740.10 7 77 1.7E-6 T 12-10-2018 AFR_07225 7e5a1bcdc5ca6f5a119a7790d8ba6ed1 219 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07225 7e5a1bcdc5ca6f5a119a7790d8ba6ed1 219 SMART SM00382 30 217 2.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_07225 7e5a1bcdc5ca6f5a119a7790d8ba6ed1 219 SUPERFAMILY SSF52540 4 218 4.34E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07225 7e5a1bcdc5ca6f5a119a7790d8ba6ed1 219 Gene3D G3DSA:3.40.50.300 1 219 1.6E-68 T 12-10-2018 AFR_07225 7e5a1bcdc5ca6f5a119a7790d8ba6ed1 219 Pfam PF00005 ABC transporter 21 169 1.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_06405 8a5eda0c7af3fe935b7f79dfd7511be8 507 Gene3D G3DSA:1.10.275.10 2 193 8.8E-69 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_06405 8a5eda0c7af3fe935b7f79dfd7511be8 507 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 501 2.1E-190 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06405 8a5eda0c7af3fe935b7f79dfd7511be8 507 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 134 150 - T 12-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 AFR_06405 8a5eda0c7af3fe935b7f79dfd7511be8 507 SUPERFAMILY SSF48557 3 491 3.61E-177 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_06405 8a5eda0c7af3fe935b7f79dfd7511be8 507 Pfam PF00221 Aromatic amino acid lyase 6 466 4.8E-182 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 AFR_06405 8a5eda0c7af3fe935b7f79dfd7511be8 507 Gene3D G3DSA:1.20.200.10 194 506 8.1E-105 T 12-10-2018 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 389 1.5E-114 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 SUPERFAMILY SSF51735 2 155 5.75E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36150 81810631fd2dcad110dd1f352c0db032 396 SUPERFAMILY SSF69055 298 390 2.75E-23 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 1 388 42.542 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 PIRSF PIRSF006205 1 395 6.2E-138 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 Pfam PF13288 DXP reductoisomerase C-terminal domain 267 383 4.3E-32 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 SUPERFAMILY SSF55347 132 269 7.19E-54 T 12-10-2018 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 Gene3D G3DSA:3.40.50.720 1 155 2.2E-44 T 12-10-2018 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 138 8.2E-37 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 Gene3D G3DSA:1.10.1740.10 307 392 3.8E-25 T 12-10-2018 AFR_36150 81810631fd2dcad110dd1f352c0db032 396 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 151 234 1.3E-37 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFR_22900 e04f4e4754e730eae96951f272174f28 259 Gene3D G3DSA:3.40.190.80 139 258 1.4E-19 T 12-10-2018 AFR_22900 e04f4e4754e730eae96951f272174f28 259 SUPERFAMILY SSF56655 1 256 1.96E-47 T 12-10-2018 AFR_22900 e04f4e4754e730eae96951f272174f28 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 4.6E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_22900 e04f4e4754e730eae96951f272174f28 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 4.6E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_22900 e04f4e4754e730eae96951f272174f28 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 4.6E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_22900 e04f4e4754e730eae96951f272174f28 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 4.6E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_22900 e04f4e4754e730eae96951f272174f28 259 Gene3D G3DSA:3.30.540.10 2 138 9.5E-24 T 12-10-2018 AFR_22900 e04f4e4754e730eae96951f272174f28 259 Pfam PF00459 Inositol monophosphatase family 13 252 3.5E-29 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_15240 afa17d84dbcda5bb0b8de8a2ed62ea04 101 Gene3D G3DSA:3.30.70.100 2 100 3.1E-16 T 12-10-2018 AFR_15240 afa17d84dbcda5bb0b8de8a2ed62ea04 101 SUPERFAMILY SSF54909 7 86 2.95E-13 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_15240 afa17d84dbcda5bb0b8de8a2ed62ea04 101 Pfam PF03992 Antibiotic biosynthesis monooxygenase 8 76 1.6E-6 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 1.2E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 211 1.2E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 PRINTS PR01042 Aspartyl-tRNA synthetase signature 373 387 1.2E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 SUPERFAMILY SSF55681 106 417 2.7E-76 T 12-10-2018 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 Pfam PF01336 OB-fold nucleic acid binding domain 17 92 1.5E-12 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 Gene3D G3DSA:2.40.50.140 2 98 9.4E-20 T 12-10-2018 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 418 37.422 T 12-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 SUPERFAMILY SSF50249 8 100 2.1E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 Gene3D G3DSA:3.30.930.10 107 418 3.1E-89 T 12-10-2018 AFR_09230 cffdfd4ab9568cb985ccda8a191f113b 418 Pfam PF00152 tRNA synthetases class II (D, K and N) 114 412 7.4E-71 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_18080 479c0adbcc65047ed5f36bbf111ecb3c 309 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 304 5.5E-97 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFR_18080 479c0adbcc65047ed5f36bbf111ecb3c 309 Gene3D G3DSA:3.40.50.300 1 236 4.2E-65 T 12-10-2018 AFR_18080 479c0adbcc65047ed5f36bbf111ecb3c 309 Pfam PF00005 ABC transporter 22 165 3.0E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18080 479c0adbcc65047ed5f36bbf111ecb3c 309 SUPERFAMILY SSF52540 6 227 1.67E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18080 479c0adbcc65047ed5f36bbf111ecb3c 309 SMART SM00382 31 214 1.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18080 479c0adbcc65047ed5f36bbf111ecb3c 309 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 Pfam PF00551 Formyl transferase 2 180 7.3E-34 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 302 31.869 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 300 3.6E-68 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 SUPERFAMILY SSF50486 204 307 3.61E-28 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 Gene3D G3DSA:3.40.50.170 1 205 4.6E-68 T 12-10-2018 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 Gene3D G3DSA:3.10.25.10 207 306 1.0E-22 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 SUPERFAMILY SSF53328 1 203 6.8E-57 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_30550 e9dd2d34c1c39ae085959f6d2f37168a 308 Pfam PF02911 Formyl transferase, C-terminal domain 203 299 8.6E-25 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_01960 3e26c2ba350ff873cf321b1fc93bc5e3 488 SUPERFAMILY SSF53041 12 161 7.32E-27 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFR_01960 3e26c2ba350ff873cf321b1fc93bc5e3 488 SMART SM00857 13 162 1.1E-35 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFR_01960 3e26c2ba350ff873cf321b1fc93bc5e3 488 Pfam PF00239 Resolvase, N terminal domain 13 150 9.6E-27 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFR_01960 3e26c2ba350ff873cf321b1fc93bc5e3 488 Gene3D G3DSA:3.40.50.1390 9 164 3.0E-30 T 12-10-2018 AFR_21390 9a25135af5c23f8f01274b969abca325 180 SUPERFAMILY SSF46894 113 176 4.42E-5 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21390 9a25135af5c23f8f01274b969abca325 180 Gene3D G3DSA:1.10.10.10 49 180 2.6E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15665 e863f9b734375622fe809a349657a7af 299 SUPERFAMILY SSF48179 159 287 1.36E-25 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_15665 e863f9b734375622fe809a349657a7af 299 PIRSF PIRSF000103 1 283 1.4E-65 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFR_15665 e863f9b734375622fe809a349657a7af 299 Gene3D G3DSA:1.10.1040.10 159 288 5.7E-26 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_15665 e863f9b734375622fe809a349657a7af 299 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 257 4.0E-25 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFR_15665 e863f9b734375622fe809a349657a7af 299 SUPERFAMILY SSF51735 1 159 9.01E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15665 e863f9b734375622fe809a349657a7af 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 158 1.3E-41 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_15665 e863f9b734375622fe809a349657a7af 299 Gene3D G3DSA:3.40.50.720 1 158 1.1E-49 T 12-10-2018 AFR_19885 3581ceb147783f308e578b636f02bcbf 199 Gene3D G3DSA:1.10.10.60 8 58 4.2E-27 T 12-10-2018 AFR_19885 3581ceb147783f308e578b636f02bcbf 199 Gene3D G3DSA:1.10.357.10 59 198 8.3E-39 T 12-10-2018 AFR_19885 3581ceb147783f308e578b636f02bcbf 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 4.6E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19885 3581ceb147783f308e578b636f02bcbf 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19885 3581ceb147783f308e578b636f02bcbf 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_19885 3581ceb147783f308e578b636f02bcbf 199 SUPERFAMILY SSF46689 8 66 9.48E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 Pfam PF04616 Glycosyl hydrolases family 43 41 321 7.9E-55 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 SUPERFAMILY SSF75005 39 322 4.28E-69 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 SMART SM00606 337 466 1.1E-42 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 Pfam PF02018 Carbohydrate binding domain 471 602 1.1E-21 T 12-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 SUPERFAMILY SSF49785 470 614 4.53E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 Gene3D G3DSA:2.60.120.260 338 465 4.4E-44 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 Gene3D G3DSA:2.115.10.20 38 335 1.8E-92 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 Pfam PF03422 Carbohydrate binding module (family 6) 345 465 9.5E-37 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 SUPERFAMILY SSF49785 337 465 5.63E-34 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29185 45834dea9a7c15acbe25c294520bfe05 616 Gene3D G3DSA:2.60.120.260 466 616 7.4E-36 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29365 7558fcb87038453a88e3147344cc977b 164 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 162 1.0E-60 T 12-10-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger AFR_03490 85d69c09a8f6de6e4916147e485491b8 468 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 464 7.8E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_03490 85d69c09a8f6de6e4916147e485491b8 468 SUPERFAMILY SSF55073 317 466 6.02E-46 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_03490 85d69c09a8f6de6e4916147e485491b8 468 SMART SM00267 301 467 4.9E-61 T 12-10-2018 IPR000160 GGDEF domain AFR_03490 85d69c09a8f6de6e4916147e485491b8 468 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 462 9.9E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_03490 85d69c09a8f6de6e4916147e485491b8 468 Gene3D G3DSA:3.30.70.270 305 467 2.1E-54 T 12-10-2018 AFR_17045 b53ab92238db689f4b8661f3cc38bac6 309 Pfam PF00781 Diacylglycerol kinase catalytic domain 17 135 1.9E-17 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFR_17045 b53ab92238db689f4b8661f3cc38bac6 309 Gene3D G3DSA:2.60.200.40 140 293 2.1E-25 T 12-10-2018 AFR_17045 b53ab92238db689f4b8661f3cc38bac6 309 Gene3D G3DSA:3.40.50.10330 10 139 2.0E-23 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_17045 b53ab92238db689f4b8661f3cc38bac6 309 SUPERFAMILY SSF111331 14 303 1.68E-53 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_31610 87d32be2423c491706200c86b32ea9c8 329 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 243 327 4.0E-13 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_31610 87d32be2423c491706200c86b32ea9c8 329 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 192 3.6E-14 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_31610 87d32be2423c491706200c86b32ea9c8 329 Gene3D G3DSA:3.40.47.10 1 181 1.1E-53 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_31610 87d32be2423c491706200c86b32ea9c8 329 SUPERFAMILY SSF53901 7 328 5.29E-41 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_31610 87d32be2423c491706200c86b32ea9c8 329 Gene3D G3DSA:3.40.47.10 183 329 7.5E-21 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_15720 1ed753cb5a45b254c282f5f1171b1103 263 SUPERFAMILY SSF51621 3 249 1.36E-60 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_15720 1ed753cb5a45b254c282f5f1171b1103 263 Gene3D G3DSA:3.20.20.60 2 258 7.8E-70 T 12-10-2018 AFR_15720 1ed753cb5a45b254c282f5f1171b1103 263 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 28 240 7.5E-26 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 Pfam PF00196 Bacterial regulatory proteins, luxR family 827 878 7.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 Pfam PF13191 AAA ATPase domain 8 162 5.8E-19 T 12-10-2018 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 Gene3D G3DSA:1.10.10.10 818 882 1.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 Gene3D G3DSA:1.25.40.10 650 813 9.7E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 SMART SM00421 825 882 8.6E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 828 842 5.4E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 842 858 5.4E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 858 870 5.4E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 SUPERFAMILY SSF52540 15 218 1.95E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 SUPERFAMILY SSF46894 815 878 2.24E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_14700 f330b1f294c3bcd09e349217ca5d9a07 889 ProSitePatterns PS00622 LuxR-type HTH domain signature. 842 869 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_24185 2f50920924645ff9272085df61aa1dbd 354 SUPERFAMILY SSF50969 109 353 2.35E-41 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFR_24185 2f50920924645ff9272085df61aa1dbd 354 Pfam PF10282 Lactonase, 7-bladed beta-propeller 101 353 1.8E-12 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller AFR_24185 2f50920924645ff9272085df61aa1dbd 354 Gene3D G3DSA:2.130.10.10 215 354 4.8E-38 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_24185 2f50920924645ff9272085df61aa1dbd 354 Gene3D G3DSA:2.130.10.10 13 214 3.6E-30 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_24185 2f50920924645ff9272085df61aa1dbd 354 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 291 330 1.7E-10 T 12-10-2018 IPR011964 YVTN beta-propeller repeat AFR_24185 2f50920924645ff9272085df61aa1dbd 354 SUPERFAMILY SSF101908 57 131 2.88E-6 T 12-10-2018 AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 Gene3D G3DSA:3.40.50.2300 167 322 3.9E-57 T 12-10-2018 AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 Gene3D G3DSA:3.40.50.2300 87 317 3.9E-57 T 12-10-2018 AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 SUPERFAMILY SSF47413 3 61 1.88E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 Gene3D G3DSA:1.10.260.40 2 60 1.1E-20 T 12-10-2018 AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 Pfam PF13377 Periplasmic binding protein-like domain 175 324 6.4E-25 T 12-10-2018 AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 SUPERFAMILY SSF53822 60 319 1.86E-45 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 48 4.3E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_35885 477a2180bca2d1b53bd0396d38cd2b0a 326 SMART SM00354 3 73 1.5E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_36480 812f3e38a1bef202383c4d456fab2181 205 SUPERFAMILY SSF56784 7 190 8.58E-32 T 12-10-2018 IPR036412 HAD-like superfamily AFR_36480 812f3e38a1bef202383c4d456fab2181 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 8.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_36480 812f3e38a1bef202383c4d456fab2181 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 8.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_36480 812f3e38a1bef202383c4d456fab2181 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 8.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_36480 812f3e38a1bef202383c4d456fab2181 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 8.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_36480 812f3e38a1bef202383c4d456fab2181 205 Gene3D G3DSA:3.40.50.1000 6 199 5.3E-33 T 12-10-2018 IPR023214 HAD superfamily AFR_36480 812f3e38a1bef202383c4d456fab2181 205 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 76 184 1.8E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_36480 812f3e38a1bef202383c4d456fab2181 205 Pfam PF13419 Haloacid dehalogenase-like hydrolase 90 185 5.8E-10 T 12-10-2018 AFR_26305 966ab8ee69af8bff8c118fcef9ff04d0 271 Gene3D G3DSA:2.60.120.620 2 262 1.3E-25 T 12-10-2018 AFR_26305 966ab8ee69af8bff8c118fcef9ff04d0 271 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 16 209 1.3E-8 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase AFR_26305 966ab8ee69af8bff8c118fcef9ff04d0 271 SUPERFAMILY SSF51197 10 246 8.97E-28 T 12-10-2018 AFR_15210 2ad7906c8b39e27968974d5b6a8b7d79 394 Gene3D G3DSA:3.80.30.30 172 394 4.8E-69 T 12-10-2018 AFR_15210 2ad7906c8b39e27968974d5b6a8b7d79 394 Gene3D G3DSA:3.40.50.12110 44 157 1.4E-32 T 12-10-2018 AFR_14990 bbcd5f05f3d2eb792844801f673a30d2 201 Gene3D G3DSA:3.40.50.720 1 192 2.7E-36 T 12-10-2018 AFR_14990 bbcd5f05f3d2eb792844801f673a30d2 201 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 81 3.3E-7 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_14990 bbcd5f05f3d2eb792844801f673a30d2 201 SUPERFAMILY SSF51735 1 183 6.22E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13955 fb0c9e812804fe2f580c798f20f5b422 141 Pfam PF04075 F420H(2)-dependent quinone reductase 30 98 8.4E-8 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_13955 fb0c9e812804fe2f580c798f20f5b422 141 Gene3D G3DSA:2.30.110.10 19 127 1.4E-11 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 SUPERFAMILY SSF53474 2 266 3.64E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 Gene3D G3DSA:3.40.50.1820 3 267 6.7E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 Pfam PF00561 alpha/beta hydrolase fold 22 253 1.5E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 PRINTS PR00412 Epoxide hydrolase signature 47 62 3.4E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 PRINTS PR00412 Epoxide hydrolase signature 106 119 3.4E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 PRINTS PR00412 Epoxide hydrolase signature 242 264 3.4E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 8.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 8.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00945 c3753080a23dcbb78d931daadd46af2a 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 8.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_39555 d9683339a579e76d9d914e0b4bcfc9b8 269 SUPERFAMILY SSF53335 23 197 2.76E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_39555 d9683339a579e76d9d914e0b4bcfc9b8 269 PIRSF PIRSF018249 2 269 4.2E-81 T 12-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 AFR_39555 d9683339a579e76d9d914e0b4bcfc9b8 269 Gene3D G3DSA:3.40.50.150 8 268 5.3E-60 T 12-10-2018 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 Gene3D G3DSA:1.10.260.40 1 56 1.7E-20 T 12-10-2018 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 SUPERFAMILY SSF53822 62 336 1.96E-65 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 Gene3D G3DSA:3.40.50.2300 162 291 1.2E-69 T 12-10-2018 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 SUPERFAMILY SSF47413 3 60 3.38E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 Gene3D G3DSA:3.40.50.2300 57 307 1.2E-69 T 12-10-2018 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 SMART SM00354 2 72 2.0E-26 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 6.2E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_31930 929c4b0de44759913ac59f0cc13ce792 340 Pfam PF13377 Periplasmic binding protein-like domain 170 331 3.6E-33 T 12-10-2018 AFR_28360 8f3c7aa5c2a154ed94032f9e90c96555 469 Pfam PF00171 Aldehyde dehydrogenase family 3 454 1.7E-142 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_28360 8f3c7aa5c2a154ed94032f9e90c96555 469 Gene3D G3DSA:3.40.309.10 234 423 4.2E-159 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_28360 8f3c7aa5c2a154ed94032f9e90c96555 469 SUPERFAMILY SSF53720 3 459 4.84E-150 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_28360 8f3c7aa5c2a154ed94032f9e90c96555 469 Gene3D G3DSA:3.40.605.10 8 449 4.2E-159 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_24620 ed7a46e3c9b5f8497b486cfa97973ba7 172 Gene3D G3DSA:1.10.10.10 109 168 3.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24620 ed7a46e3c9b5f8497b486cfa97973ba7 172 Gene3D G3DSA:1.10.1740.10 1 108 4.4E-21 T 12-10-2018 AFR_24620 ed7a46e3c9b5f8497b486cfa97973ba7 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 165 5.0E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_24620 ed7a46e3c9b5f8497b486cfa97973ba7 172 Pfam PF04542 Sigma-70 region 2 21 83 1.2E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24620 ed7a46e3c9b5f8497b486cfa97973ba7 172 SUPERFAMILY SSF88659 102 164 1.64E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_24620 ed7a46e3c9b5f8497b486cfa97973ba7 172 SUPERFAMILY SSF88946 1 98 1.82E-19 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_24620 ed7a46e3c9b5f8497b486cfa97973ba7 172 Pfam PF08281 Sigma-70, region 4 109 161 3.3E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_06615 e397b6b6058ecae2154e774491379367 313 Pfam PF03707 Bacterial signalling protein N terminal repeat 184 236 3.4E-5 T 12-10-2018 IPR005330 MHYT domain AFR_06615 e397b6b6058ecae2154e774491379367 313 Pfam PF03707 Bacterial signalling protein N terminal repeat 122 178 1.3E-14 T 12-10-2018 IPR005330 MHYT domain AFR_06615 e397b6b6058ecae2154e774491379367 313 Pfam PF03707 Bacterial signalling protein N terminal repeat 57 108 2.4E-15 T 12-10-2018 IPR005330 MHYT domain AFR_36170 0e7e78f51d6af1e08c95f3ab95cb1cde 235 Gene3D G3DSA:1.10.357.10 1 235 5.7E-67 T 12-10-2018 AFR_36170 0e7e78f51d6af1e08c95f3ab95cb1cde 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 9.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36170 0e7e78f51d6af1e08c95f3ab95cb1cde 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 9.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36170 0e7e78f51d6af1e08c95f3ab95cb1cde 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 5.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36170 0e7e78f51d6af1e08c95f3ab95cb1cde 235 SUPERFAMILY SSF46689 8 81 2.24E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_36170 0e7e78f51d6af1e08c95f3ab95cb1cde 235 SUPERFAMILY SSF48498 93 229 3.78E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02105 5c82b33b9b58323ee1f128f6f06c7c51 271 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 2 264 37.848 T 12-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 AFR_02105 5c82b33b9b58323ee1f128f6f06c7c51 271 SUPERFAMILY SSF53850 3 262 7.7E-77 T 12-10-2018 AFR_02105 5c82b33b9b58323ee1f128f6f06c7c51 271 Pfam PF02621 Menaquinone biosynthesis 3 258 5.5E-88 T 12-10-2018 IPR003773 Menaquinone biosynthesis enzyme AFR_02105 5c82b33b9b58323ee1f128f6f06c7c51 271 Gene3D G3DSA:3.40.190.10 79 174 3.2E-97 T 12-10-2018 AFR_02105 5c82b33b9b58323ee1f128f6f06c7c51 271 Gene3D G3DSA:3.40.190.10 5 259 3.2E-97 T 12-10-2018 AFR_24425 c774cd879ec179ca5b85ea2673b0baa5 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 282 4.2E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_24425 c774cd879ec179ca5b85ea2673b0baa5 289 SUPERFAMILY SSF161098 90 276 2.22E-37 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24425 c774cd879ec179ca5b85ea2673b0baa5 289 Gene3D G3DSA:1.10.3720.10 87 281 1.7E-32 T 12-10-2018 IPR035906 MetI-like superfamily AFR_32550 5c10a43ba5f8c1325267c8bda84e45b2 325 SUPERFAMILY SSF53300 88 283 2.97E-25 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_32550 5c10a43ba5f8c1325267c8bda84e45b2 325 Pfam PF13519 von Willebrand factor type A domain 88 208 3.0E-16 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_32550 5c10a43ba5f8c1325267c8bda84e45b2 325 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 2.8E-6 T 12-10-2018 IPR024163 Aerotolerance regulator, N-terminal AFR_32550 5c10a43ba5f8c1325267c8bda84e45b2 325 SMART SM00327 85 290 7.3E-13 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_32550 5c10a43ba5f8c1325267c8bda84e45b2 325 Gene3D G3DSA:3.40.50.410 80 286 1.7E-41 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 SUPERFAMILY SSF51735 4 242 8.92E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 9.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 9.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 9.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 9.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 9.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 Gene3D G3DSA:3.40.50.720 2 242 3.0E-72 T 12-10-2018 AFR_15645 6b9674810b6e6f73834b1275429c45bb 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 240 4.5E-62 T 12-10-2018 AFR_26375 22b2751fcc91538aefca86c25fe5a98e 210 Gene3D G3DSA:3.40.50.150 1 209 1.0E-69 T 12-10-2018 AFR_26375 22b2751fcc91538aefca86c25fe5a98e 210 SUPERFAMILY SSF53335 5 209 2.19E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_26375 22b2751fcc91538aefca86c25fe5a98e 210 Pfam PF01596 O-methyltransferase 15 209 1.6E-57 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 AFR_24830 3f902c3b09da3678e66591473cf52466 783 Pfam PF07730 Histidine kinase 179 245 8.6E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_24830 3f902c3b09da3678e66591473cf52466 783 SUPERFAMILY SSF55874 284 371 5.46E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24830 3f902c3b09da3678e66591473cf52466 783 Gene3D G3DSA:3.30.565.10 251 372 2.0E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32670 11a0236c859e93be7f38d6e0d7db0ffd 276 Pfam PF14158 YndJ-like protein 6 254 1.5E-84 T 12-10-2018 IPR025450 YndJ-like protein AFR_29075 653e085d6c7e2e3b779593e230ea1e4e 453 Pfam PF03422 Carbohydrate binding module (family 6) 28 154 2.4E-35 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_29075 653e085d6c7e2e3b779593e230ea1e4e 453 SMART SM00606 20 155 5.8E-44 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_29075 653e085d6c7e2e3b779593e230ea1e4e 453 Gene3D G3DSA:2.60.120.260 13 155 8.8E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_29075 653e085d6c7e2e3b779593e230ea1e4e 453 Pfam PF09362 Domain of unknown function (DUF1996) 220 428 1.3E-47 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_29075 653e085d6c7e2e3b779593e230ea1e4e 453 SUPERFAMILY SSF49785 22 155 5.27E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_11325 159136e0f630c50bed927e660fd036c5 373 Gene3D G3DSA:2.120.10.80 17 219 3.0E-5 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFR_11325 159136e0f630c50bed927e660fd036c5 373 SUPERFAMILY SSF50998 36 359 4.0E-12 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_21850 c9b938e8a99d80c5dda0190d1f454ed0 281 Gene3D G3DSA:3.40.50.1820 2 274 2.7E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21850 c9b938e8a99d80c5dda0190d1f454ed0 281 SUPERFAMILY SSF53474 4 274 4.61E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21850 c9b938e8a99d80c5dda0190d1f454ed0 281 Pfam PF00561 alpha/beta hydrolase fold 22 260 9.3E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 Pfam PF04539 Sigma-70 region 3 100 145 1.4E-8 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 Pfam PF04542 Sigma-70 region 2 15 86 6.9E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 SUPERFAMILY SSF88659 88 155 7.41E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_31875 e4f5f204c5964941d9889576a318ed81 282 Gene3D G3DSA:1.20.140.160 85 233 7.8E-37 T 12-10-2018 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 228 3.6E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 Gene3D G3DSA:1.10.1740.10 4 84 2.0E-20 T 12-10-2018 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 PIRSF PIRSF000770 1 251 6.9E-56 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 SUPERFAMILY SSF88659 153 231 8.78E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_31875 e4f5f204c5964941d9889576a318ed81 282 Pfam PF04545 Sigma-70, region 4 179 227 2.3E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_31875 e4f5f204c5964941d9889576a318ed81 282 SUPERFAMILY SSF88946 11 86 4.32E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_18870 edf2d059c5fba6d92a84f310e98f7327 431 Pfam PF04434 SWIM zinc finger 394 425 1.8E-6 T 12-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 AFR_36610 f4529d3ad793d2a9a9a06b488a1d7539 213 Pfam PF12028 Protein of unknown function (DUF3515) 29 200 2.2E-21 T 12-10-2018 IPR021903 Protein of unknown function DUF3515 AFR_37990 125f59233dfde38ea60dd40d4455f1e3 653 Pfam PF00005 ABC transporter 405 561 4.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_37990 125f59233dfde38ea60dd40d4455f1e3 653 Gene3D G3DSA:3.40.50.300 378 634 1.4E-77 T 12-10-2018 AFR_37990 125f59233dfde38ea60dd40d4455f1e3 653 ProSitePatterns PS00211 ABC transporters family signature. 530 544 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_37990 125f59233dfde38ea60dd40d4455f1e3 653 SUPERFAMILY SSF52540 385 631 4.24E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37990 125f59233dfde38ea60dd40d4455f1e3 653 SMART SM00382 414 607 9.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_29225 bc8ad36ce9165b3e2d9320200cd01ec7 242 SUPERFAMILY SSF52540 5 180 2.88E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29225 bc8ad36ce9165b3e2d9320200cd01ec7 242 Gene3D G3DSA:3.40.50.300 1 215 2.5E-7 T 12-10-2018 AFR_19575 7873192f32e785070a22df8964b00766 373 SMART SM00637 31 130 8.6E-45 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_19575 7873192f32e785070a22df8964b00766 373 Gene3D G3DSA:2.60.40.290 25 133 4.1E-35 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_19575 7873192f32e785070a22df8964b00766 373 Gene3D G3DSA:3.40.50.1110 171 373 1.1E-66 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_19575 7873192f32e785070a22df8964b00766 373 SUPERFAMILY SSF49384 27 132 1.6E-31 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_19575 7873192f32e785070a22df8964b00766 373 SUPERFAMILY SSF52266 164 368 3.38E-37 T 12-10-2018 AFR_19575 7873192f32e785070a22df8964b00766 373 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 176 357 4.6E-21 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_19575 7873192f32e785070a22df8964b00766 373 Pfam PF00553 Cellulose binding domain 31 130 3.7E-30 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_07140 10c85b39258678b4f60d09909de97507 161 Gene3D G3DSA:1.10.10.10 5 144 4.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07140 10c85b39258678b4f60d09909de97507 161 Pfam PF01047 MarR family 43 95 1.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_07140 10c85b39258678b4f60d09909de97507 161 SUPERFAMILY SSF46785 22 143 8.99E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_07140 10c85b39258678b4f60d09909de97507 161 SMART SM00347 31 131 2.1E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_17935 f1e24ec6746800923212760267c2afc4 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17935 f1e24ec6746800923212760267c2afc4 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17935 f1e24ec6746800923212760267c2afc4 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17935 f1e24ec6746800923212760267c2afc4 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_17935 f1e24ec6746800923212760267c2afc4 231 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 226 3.1E-26 T 12-10-2018 AFR_17935 f1e24ec6746800923212760267c2afc4 231 SUPERFAMILY SSF51735 5 225 9.6E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17935 f1e24ec6746800923212760267c2afc4 231 Gene3D G3DSA:3.40.50.720 5 229 2.8E-44 T 12-10-2018 AFR_24985 21264178bd6935f931c24b47cd35db0c 116 Gene3D G3DSA:3.60.90.10 16 116 3.5E-5 T 12-10-2018 AFR_24985 21264178bd6935f931c24b47cd35db0c 116 Pfam PF02675 S-adenosylmethionine decarboxylase 27 115 1.4E-6 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFR_07230 a866fca5053592fa1404ffc68fe18437 392 Pfam PF02687 FtsX-like permease family 298 385 2.1E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_07230 a866fca5053592fa1404ffc68fe18437 392 Pfam PF12704 MacB-like periplasmic core domain 29 234 1.2E-17 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_33460 86828466410e0e737867ed38b2b77e94 108 SUPERFAMILY SSF159894 6 98 3.66E-11 T 12-10-2018 AFR_33460 86828466410e0e737867ed38b2b77e94 108 Pfam PF04993 TfoX N-terminal domain 16 98 1.5E-11 T 12-10-2018 IPR007076 TfoX, N-terminal AFR_26100 b718c54bff1fc2afb64fed5c69fcaab4 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.9E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_26100 b718c54bff1fc2afb64fed5c69fcaab4 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 3.9E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_26100 b718c54bff1fc2afb64fed5c69fcaab4 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.9E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_26100 b718c54bff1fc2afb64fed5c69fcaab4 64 Gene3D G3DSA:3.30.70.20 1 64 3.4E-20 T 12-10-2018 AFR_26100 b718c54bff1fc2afb64fed5c69fcaab4 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 2.4E-13 T 12-10-2018 AFR_26100 b718c54bff1fc2afb64fed5c69fcaab4 64 SUPERFAMILY SSF54862 3 62 8.76E-13 T 12-10-2018 AFR_41150 0e5c874e9270b5ac8cf0b6a5f81447e2 384 Gene3D G3DSA:3.10.180.10 180 384 6.6E-77 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_41150 0e5c874e9270b5ac8cf0b6a5f81447e2 384 Gene3D G3DSA:3.10.180.10 1 171 3.7E-51 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_41150 0e5c874e9270b5ac8cf0b6a5f81447e2 384 PIRSF PIRSF009283 5 384 8.6E-129 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 AFR_41150 0e5c874e9270b5ac8cf0b6a5f81447e2 384 SUPERFAMILY SSF54593 12 371 2.51E-88 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_41150 0e5c874e9270b5ac8cf0b6a5f81447e2 384 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 187 338 7.3E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_41150 0e5c874e9270b5ac8cf0b6a5f81447e2 384 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 19 384 4.1E-127 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 AFR_10970 06e82811cf7cfc42b50d5bff20c73f65 488 Gene3D G3DSA:3.40.350.10 44 184 1.5E-18 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFR_10970 06e82811cf7cfc42b50d5bff20c73f65 488 Pfam PF05195 Aminopeptidase P, N-terminal domain 47 165 4.3E-20 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 AFR_10970 06e82811cf7cfc42b50d5bff20c73f65 488 SUPERFAMILY SSF53092 46 189 7.32E-24 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFR_10970 06e82811cf7cfc42b50d5bff20c73f65 488 SUPERFAMILY SSF55920 212 481 2.49E-60 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like AFR_10970 06e82811cf7cfc42b50d5bff20c73f65 488 SMART SM01011 43 182 3.8E-33 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 AFR_10970 06e82811cf7cfc42b50d5bff20c73f65 488 Gene3D G3DSA:3.90.230.10 211 484 4.2E-73 T 12-10-2018 AFR_10970 06e82811cf7cfc42b50d5bff20c73f65 488 Pfam PF00557 Metallopeptidase family M24 219 455 1.2E-45 T 12-10-2018 IPR000994 Peptidase M24 AFR_06755 12576e93356e56b6e5bc5ddfcc8c3c45 410 Gene3D G3DSA:2.40.440.10 258 395 6.8E-91 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_06755 12576e93356e56b6e5bc5ddfcc8c3c45 410 Gene3D G3DSA:2.60.40.3710 164 407 6.8E-91 T 12-10-2018 AFR_06755 12576e93356e56b6e5bc5ddfcc8c3c45 410 Gene3D G3DSA:2.60.40.3780 58 154 3.5E-12 T 12-10-2018 AFR_06755 12576e93356e56b6e5bc5ddfcc8c3c45 410 SUPERFAMILY SSF141523 259 381 1.7E-28 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_06755 12576e93356e56b6e5bc5ddfcc8c3c45 410 Pfam PF03734 L,D-transpeptidase catalytic domain 263 381 1.9E-14 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_26505 4dee20cf1729116927e8c5e19bad7dbd 113 Gene3D G3DSA:1.10.10.10 1 109 4.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26505 4dee20cf1729116927e8c5e19bad7dbd 113 Pfam PF12840 Helix-turn-helix domain 8 64 8.4E-17 T 12-10-2018 AFR_26505 4dee20cf1729116927e8c5e19bad7dbd 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 8.5E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26505 4dee20cf1729116927e8c5e19bad7dbd 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 8.5E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26505 4dee20cf1729116927e8c5e19bad7dbd 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 8.5E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_26505 4dee20cf1729116927e8c5e19bad7dbd 113 SUPERFAMILY SSF46785 2 100 1.41E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26505 4dee20cf1729116927e8c5e19bad7dbd 113 SMART SM00418 8 86 8.1E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_01315 6e33abe1cbbe165df459817051d3aeaa 108 SUPERFAMILY SSF52091 6 104 9.81E-21 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01315 6e33abe1cbbe165df459817051d3aeaa 108 Pfam PF13466 STAS domain 20 98 8.4E-14 T 12-10-2018 IPR002645 STAS domain AFR_01315 6e33abe1cbbe165df459817051d3aeaa 108 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 6 106 2.7E-19 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_01315 6e33abe1cbbe165df459817051d3aeaa 108 Gene3D G3DSA:3.30.750.24 3 108 6.3E-24 T 12-10-2018 IPR036513 STAS domain superfamily AFR_00775 f75336d6d48c3a816b69ada7c9b9ccce 69 SUPERFAMILY SSF46955 11 61 8.24E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_00775 f75336d6d48c3a816b69ada7c9b9ccce 69 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.7E-9 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_00775 f75336d6d48c3a816b69ada7c9b9ccce 69 Gene3D G3DSA:1.10.1660.10 11 67 1.0E-12 T 12-10-2018 AFR_00775 f75336d6d48c3a816b69ada7c9b9ccce 69 Pfam PF12728 Helix-turn-helix domain 11 61 5.7E-13 T 12-10-2018 AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 SMART SM00354 2 69 2.8E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 Pfam PF13377 Periplasmic binding protein-like domain 170 319 1.0E-30 T 12-10-2018 AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 Gene3D G3DSA:1.10.260.40 3 57 2.6E-11 T 12-10-2018 AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 Gene3D G3DSA:3.40.50.2300 161 279 7.0E-65 T 12-10-2018 AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 Gene3D G3DSA:3.40.50.2300 58 294 7.0E-65 T 12-10-2018 AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 46 3.4E-11 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 SUPERFAMILY SSF53822 58 321 1.92E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_01365 dd61c5abda9760b67e059326c626ad4e 324 SUPERFAMILY SSF47413 5 49 2.67E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_21520 213d97d4644f8e2e573c8bb4ce2484df 164 Pfam PF13302 Acetyltransferase (GNAT) domain 6 141 9.1E-23 T 12-10-2018 IPR000182 GNAT domain AFR_21520 213d97d4644f8e2e573c8bb4ce2484df 164 SUPERFAMILY SSF55729 6 148 1.49E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_21520 213d97d4644f8e2e573c8bb4ce2484df 164 Gene3D G3DSA:3.40.630.30 4 153 1.1E-33 T 12-10-2018 AFR_29065 13ac60e0d6d781732b7efde1257c6a89 550 SMART SM00220 19 271 1.2E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_29065 13ac60e0d6d781732b7efde1257c6a89 550 Gene3D G3DSA:3.30.200.20 11 94 3.3E-19 T 12-10-2018 AFR_29065 13ac60e0d6d781732b7efde1257c6a89 550 Gene3D G3DSA:1.10.510.10 95 273 4.7E-40 T 12-10-2018 AFR_29065 13ac60e0d6d781732b7efde1257c6a89 550 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 47 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_29065 13ac60e0d6d781732b7efde1257c6a89 550 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_29065 13ac60e0d6d781732b7efde1257c6a89 550 SUPERFAMILY SSF56112 12 278 7.01E-62 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_29065 13ac60e0d6d781732b7efde1257c6a89 550 Pfam PF00069 Protein kinase domain 19 267 6.0E-38 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_11870 5d5708fe809b602fecb69bbc42f0fcb6 269 SUPERFAMILY SSF53474 34 266 1.34E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11870 5d5708fe809b602fecb69bbc42f0fcb6 269 Pfam PF12697 Alpha/beta hydrolase family 40 258 2.3E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11870 5d5708fe809b602fecb69bbc42f0fcb6 269 Gene3D G3DSA:3.40.50.1820 33 269 1.6E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_38195 fedac856e2cd59c1f6df392d35810598 786 Gene3D G3DSA:1.10.3810.10 65 276 4.0E-66 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_38195 fedac856e2cd59c1f6df392d35810598 786 Pfam PF00905 Penicillin binding protein transpeptidase domain 364 640 2.5E-21 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_38195 fedac856e2cd59c1f6df392d35810598 786 SUPERFAMILY SSF53955 60 281 7.87E-63 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_38195 fedac856e2cd59c1f6df392d35810598 786 Gene3D G3DSA:3.30.10.20 711 771 5.6E-12 T 12-10-2018 AFR_38195 fedac856e2cd59c1f6df392d35810598 786 Pfam PF00912 Transglycosylase 73 259 1.4E-54 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_38195 fedac856e2cd59c1f6df392d35810598 786 SUPERFAMILY SSF56601 245 703 7.32E-64 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_38195 fedac856e2cd59c1f6df392d35810598 786 Gene3D G3DSA:3.40.710.10 312 710 2.4E-65 T 12-10-2018 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 337 2.6E-69 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 336 1.2E-125 T 12-10-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 SUPERFAMILY SSF51569 5 337 2.2E-93 T 12-10-2018 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 336 8.5E-77 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 PIRSF PIRSF001359 6 338 1.2E-60 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFR_00630 bc6b394558ba28d5ef605db5c2e2b912 341 Gene3D G3DSA:3.20.20.70 1 341 6.2E-118 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_20365 a013478e9e78a8afc5dc094abaef1cf7 89 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 78 3.3E-38 T 12-10-2018 IPR018735 Protein of unknown function DUF2277 AFR_16520 b8c937cbf7acd39c1efb53ab4261e8dd 518 SUPERFAMILY SSF53448 93 376 8.06E-37 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16520 b8c937cbf7acd39c1efb53ab4261e8dd 518 Gene3D G3DSA:3.90.550.10 84 299 1.7E-61 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16520 b8c937cbf7acd39c1efb53ab4261e8dd 518 Pfam PF13632 Glycosyl transferase family group 2 174 364 7.1E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_05230 e1f5ff99e686e14109a79f78f18fbb73 303 Pfam PF00005 ABC transporter 20 159 3.9E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_05230 e1f5ff99e686e14109a79f78f18fbb73 303 Gene3D G3DSA:3.40.50.300 1 227 1.1E-54 T 12-10-2018 AFR_05230 e1f5ff99e686e14109a79f78f18fbb73 303 SMART SM00382 27 226 1.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_05230 e1f5ff99e686e14109a79f78f18fbb73 303 SUPERFAMILY SSF52540 4 222 6.82E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00075 4fa3da10a3876852b7772966df75b0fe 120 Pfam PF00293 NUDIX domain 3 101 1.2E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_00075 4fa3da10a3876852b7772966df75b0fe 120 SUPERFAMILY SSF55811 2 98 1.76E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_00075 4fa3da10a3876852b7772966df75b0fe 120 PRINTS PR00502 NUDIX hydrolase family signature 22 36 4.1E-9 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_00075 4fa3da10a3876852b7772966df75b0fe 120 PRINTS PR00502 NUDIX hydrolase family signature 36 51 4.1E-9 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_00075 4fa3da10a3876852b7772966df75b0fe 120 Gene3D G3DSA:3.90.79.10 1 103 9.8E-25 T 12-10-2018 AFR_00075 4fa3da10a3876852b7772966df75b0fe 120 ProSitePatterns PS00893 Nudix box signature. 27 48 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Pfam PF13361 UvrD-like helicase C-terminal domain 409 548 2.1E-12 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 SUPERFAMILY SSF52540 60 824 2.13E-111 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Gene3D G3DSA:3.40.50.300 258 393 1.6E-31 T 12-10-2018 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Pfam PF12705 PD-(D/E)XK nuclease superfamily 995 1140 1.3E-11 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 SUPERFAMILY SSF52980 1001 1138 6.43E-7 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Gene3D G3DSA:3.40.50.300 428 536 1.9E-18 T 12-10-2018 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Pfam PF00580 UvrD/REP helicase N-terminal domain 264 361 2.8E-21 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Pfam PF00580 UvrD/REP helicase N-terminal domain 61 187 3.4E-25 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Gene3D G3DSA:3.90.320.10 967 1143 7.5E-7 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Gene3D G3DSA:3.40.50.300 56 227 5.4E-34 T 12-10-2018 AFR_38475 a3eca4b607e2a3e32247decf367cb361 1168 Pfam PF13361 UvrD-like helicase C-terminal domain 693 800 1.3E-13 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_33080 a0390d23f26517737464b5c56a447345 409 Gene3D G3DSA:3.90.1150.10 12 404 2.7E-135 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_33080 a0390d23f26517737464b5c56a447345 409 SUPERFAMILY SSF53383 6 407 7.72E-79 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_33080 a0390d23f26517737464b5c56a447345 409 TIGRFAM TIGR01814 kynureninase: kynureninase 9 405 1.5E-79 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 AFR_33080 a0390d23f26517737464b5c56a447345 409 Hamap MF_01970 Kynureninase [kynU]. 2 405 33.396 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 AFR_33080 a0390d23f26517737464b5c56a447345 409 PIRSF PIRSF038800 1 409 1.8E-148 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 AFR_33080 a0390d23f26517737464b5c56a447345 409 Gene3D G3DSA:3.40.640.10 46 309 2.7E-135 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_33080 a0390d23f26517737464b5c56a447345 409 Pfam PF00266 Aminotransferase class-V 118 328 3.8E-23 T 12-10-2018 IPR000192 Aminotransferase class V domain AFR_04200 764b28e85b207a8a3a5af13860378e00 224 Pfam PF04029 2-phosphosulpholactate phosphatase 12 205 1.1E-33 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 AFR_04200 764b28e85b207a8a3a5af13860378e00 224 Gene3D G3DSA:3.90.1560.10 3 220 3.1E-40 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 AFR_04200 764b28e85b207a8a3a5af13860378e00 224 SUPERFAMILY SSF142823 10 211 8.37E-36 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 AFR_26175 cd04332f93b57754c0aadd8b63c66f66 220 SUPERFAMILY SSF109854 2 127 2.87E-17 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_26175 cd04332f93b57754c0aadd8b63c66f66 220 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 113 9.2E-14 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_26175 cd04332f93b57754c0aadd8b63c66f66 220 Gene3D G3DSA:1.20.120.450 1 125 8.2E-13 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_26175 cd04332f93b57754c0aadd8b63c66f66 220 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 190 2.9E-27 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_14300 160a64990a51fa131f935d375e343353 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_14300 160a64990a51fa131f935d375e343353 299 Gene3D G3DSA:3.40.50.300 1 228 7.5E-55 T 12-10-2018 AFR_14300 160a64990a51fa131f935d375e343353 299 SMART SM00382 30 215 2.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_14300 160a64990a51fa131f935d375e343353 299 Pfam PF00005 ABC transporter 22 159 5.2E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_14300 160a64990a51fa131f935d375e343353 299 SUPERFAMILY SSF52540 6 218 3.52E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19105 89bf849270b2ca38af60e0f07751d328 273 SUPERFAMILY SSF56300 6 257 1.38E-24 T 12-10-2018 AFR_19105 89bf849270b2ca38af60e0f07751d328 273 Gene3D G3DSA:3.60.21.10 4 253 6.1E-8 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_19105 89bf849270b2ca38af60e0f07751d328 273 Pfam PF00149 Calcineurin-like phosphoesterase 4 237 6.1E-17 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_27580 204c65cdc8715c064358a328c790040f 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 243 8.8E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_27580 204c65cdc8715c064358a328c790040f 254 SUPERFAMILY SSF161098 52 236 4.06E-20 T 12-10-2018 IPR035906 MetI-like superfamily AFR_27580 204c65cdc8715c064358a328c790040f 254 Gene3D G3DSA:1.10.3720.10 47 246 8.6E-17 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15130 8f6230edb58f4e2a3c23bc460099c9d2 298 Gene3D G3DSA:3.40.50.300 1 235 2.7E-55 T 12-10-2018 AFR_15130 8f6230edb58f4e2a3c23bc460099c9d2 298 SUPERFAMILY SSF52540 3 222 1.59E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15130 8f6230edb58f4e2a3c23bc460099c9d2 298 Pfam PF00005 ABC transporter 19 157 1.4E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_15130 8f6230edb58f4e2a3c23bc460099c9d2 298 SMART SM00382 27 205 9.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_00790 a2da0cd1c0ccd44f35f564aa6a16b19a 186 SUPERFAMILY SSF56399 9 182 3.31E-54 T 12-10-2018 AFR_00790 a2da0cd1c0ccd44f35f564aa6a16b19a 186 Gene3D G3DSA:3.20.170.30 100 186 1.0E-28 T 12-10-2018 AFR_00790 a2da0cd1c0ccd44f35f564aa6a16b19a 186 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 7 181 30.712 T 12-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 AFR_00790 a2da0cd1c0ccd44f35f564aa6a16b19a 186 Gene3D G3DSA:1.10.10.970 7 78 5.2E-14 T 12-10-2018 AFR_00790 a2da0cd1c0ccd44f35f564aa6a16b19a 186 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 7 174 7.3E-41 T 12-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 AFR_32830 9fbfcd240008384df4dd1285afc0513f 431 Pfam PF07730 Histidine kinase 183 248 1.3E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_32830 9fbfcd240008384df4dd1285afc0513f 431 SUPERFAMILY SSF55874 266 385 2.45E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32830 9fbfcd240008384df4dd1285afc0513f 431 Gene3D G3DSA:3.30.565.10 259 387 3.9E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_05600 4c6bd4e84c44f1943a31c4a2fa0eafb7 274 SUPERFAMILY SSF56281 5 272 3.14E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_05600 4c6bd4e84c44f1943a31c4a2fa0eafb7 274 Pfam PF00753 Metallo-beta-lactamase superfamily 60 270 1.6E-30 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_05600 4c6bd4e84c44f1943a31c4a2fa0eafb7 274 Gene3D G3DSA:3.60.15.10 1 274 5.0E-71 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_05600 4c6bd4e84c44f1943a31c4a2fa0eafb7 274 SMART SM00849 57 270 1.4E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 PRINTS PR01009 Flagellar M-ring protein signature 196 214 2.9E-25 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 PRINTS PR01009 Flagellar M-ring protein signature 340 364 2.9E-25 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 PRINTS PR01009 Flagellar M-ring protein signature 267 285 2.9E-25 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 PRINTS PR01009 Flagellar M-ring protein signature 121 139 2.9E-25 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 PRINTS PR01009 Flagellar M-ring protein signature 153 167 2.9E-25 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 12 529 2.6E-83 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 Pfam PF01514 Secretory protein of YscJ/FliF family 31 220 2.4E-69 T 12-10-2018 IPR006182 Secretory protein YscJ/FliF AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 Pfam PF08345 Flagellar M-ring protein C-terminal 254 404 2.6E-33 T 12-10-2018 IPR013556 Flagellar M-ring C-terminal AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 Gene3D G3DSA:3.30.300.30 120 222 3.9E-13 T 12-10-2018 AFR_40435 a8b462627c77c823863fc0814d50a4d5 533 PIRSF PIRSF004862 1 533 1.5E-137 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 293 487 3.8E-58 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Gene3D G3DSA:3.90.740.10 299 497 4.3E-195 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 PRINTS PR00985 Leucyl-tRNA synthetase signature 664 674 9.6E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 169 9.6E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 PRINTS PR00985 Leucyl-tRNA synthetase signature 287 306 9.6E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 PRINTS PR00985 Leucyl-tRNA synthetase signature 631 653 9.6E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 PRINTS PR00985 Leucyl-tRNA synthetase signature 258 271 9.6E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 PRINTS PR00985 Leucyl-tRNA synthetase signature 583 601 9.6E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 PRINTS PR00985 Leucyl-tRNA synthetase signature 225 241 9.6E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 SUPERFAMILY SSF52374 22 760 4.98E-110 T 12-10-2018 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Pfam PF09334 tRNA synthetases class I (M) 65 168 4.8E-13 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Gene3D G3DSA:1.10.730.10 724 873 4.3E-195 T 12-10-2018 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Gene3D G3DSA:3.10.20.590 881 939 9.0E-17 T 12-10-2018 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 219 939 1.7E-215 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Gene3D G3DSA:3.10.330.110 674 723 4.3E-195 T 12-10-2018 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Pfam PF08264 Anticodon-binding domain of tRNA 793 906 1.1E-15 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 78 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Gene3D G3DSA:3.40.50.620 219 673 4.3E-195 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 SUPERFAMILY SSF50677 298 495 1.04E-45 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Gene3D G3DSA:3.40.50.620 56 173 4.3E-42 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 SUPERFAMILY SSF47323 758 939 1.53E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_09935 f97f557c1f8ecfcdcbe9f319a2ae3fd1 939 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 17 939 21.365 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFR_36820 f0857f47d6771153d983163b41affe6a 203 SUPERFAMILY SSF48498 96 194 1.47E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_36820 f0857f47d6771153d983163b41affe6a 203 SUPERFAMILY SSF46689 5 70 7.7E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_36820 f0857f47d6771153d983163b41affe6a 203 Gene3D G3DSA:1.10.357.10 2 197 2.2E-34 T 12-10-2018 AFR_36820 f0857f47d6771153d983163b41affe6a 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.2E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36820 f0857f47d6771153d983163b41affe6a 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 7.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36820 f0857f47d6771153d983163b41affe6a 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 SUPERFAMILY SSF52172 3 133 5.83E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_33510 be0f613be89db49971bdaa280ade4f67 205 Gene3D G3DSA:3.40.50.12740 2 205 1.4E-70 T 12-10-2018 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 Pfam PF00072 Response regulator receiver domain 5 115 7.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 SMART SM00421 142 199 2.2E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 SUPERFAMILY SSF46894 133 205 5.78E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 1.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 SMART SM00448 2 115 9.1E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 5.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 5.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33510 be0f613be89db49971bdaa280ade4f67 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 5.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13410 22157ee17e1a6977e634fad985dcd8da 139 Gene3D G3DSA:3.30.360.10 1 139 1.8E-24 T 12-10-2018 AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 Gene3D G3DSA:2.60.40.10 1 177 1.3E-45 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 SMART SM00642 183 539 1.3E-4 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 Gene3D G3DSA:3.20.20.80 178 550 3.4E-159 T 12-10-2018 AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 Gene3D G3DSA:1.20.58.280 80 158 1.3E-45 T 12-10-2018 AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 SUPERFAMILY SSF51445 183 546 1.19E-78 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 Gene3D G3DSA:2.60.40.1180 551 643 1.8E-28 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 641 40.881 T 12-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 AFR_27095 57a751c51cf43b8fce754ef564c37f97 643 Pfam PF11896 Domain of unknown function (DUF3416) 1 177 5.5E-42 T 12-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 AFR_16800 2881aa0405a7e3b0fd55d5a8b4f6ae98 479 Pfam PF01554 MatE 37 202 7.6E-15 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_16800 2881aa0405a7e3b0fd55d5a8b4f6ae98 479 Pfam PF01554 MatE 267 421 1.3E-15 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_16800 2881aa0405a7e3b0fd55d5a8b4f6ae98 479 PIRSF PIRSF006603 14 470 2.1E-65 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_24430 42e36c4d355cbdaf8020238edf0e39c4 280 Pfam PF12796 Ankyrin repeats (3 copies) 51 129 1.3E-10 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFR_24430 42e36c4d355cbdaf8020238edf0e39c4 280 Gene3D G3DSA:1.25.40.20 23 240 1.6E-26 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_24430 42e36c4d355cbdaf8020238edf0e39c4 280 SUPERFAMILY SSF48403 50 155 4.66E-23 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_24430 42e36c4d355cbdaf8020238edf0e39c4 280 SMART SM00248 69 98 0.49 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_24430 42e36c4d355cbdaf8020238edf0e39c4 280 SMART SM00248 102 131 2.1 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_24430 42e36c4d355cbdaf8020238edf0e39c4 280 SMART SM00248 35 65 2200.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_07730 68ab1a25f93e7ad6252ac0c1a418c621 211 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 198 5.6E-51 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_07730 68ab1a25f93e7ad6252ac0c1a418c621 211 PIRSF PIRSF000709 2 110 1.1E-5 T 12-10-2018 AFR_07730 68ab1a25f93e7ad6252ac0c1a418c621 211 Gene3D G3DSA:3.40.50.1240 1 205 2.2E-60 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_07730 68ab1a25f93e7ad6252ac0c1a418c621 211 SMART SM00855 4 158 2.1E-18 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_07730 68ab1a25f93e7ad6252ac0c1a418c621 211 SUPERFAMILY SSF53254 1 208 3.87E-55 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_00560 77423b0d211ac07482b819c3701c53ba 301 Gene3D G3DSA:2.130.10.10 91 244 3.1E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_00560 77423b0d211ac07482b819c3701c53ba 301 SUPERFAMILY SSF110296 98 242 8.11E-12 T 12-10-2018 AFR_20940 a9f68d666b5aae6338ec1b8af4ae05b2 306 Gene3D G3DSA:1.10.3720.10 34 304 1.6E-30 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20940 a9f68d666b5aae6338ec1b8af4ae05b2 306 SUPERFAMILY SSF161098 33 297 2.09E-31 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 164 264 2.7E-21 T 12-10-2018 AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 SUPERFAMILY SSF51735 5 265 1.73E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 Gene3D G3DSA:3.40.50.720 1 267 4.7E-36 T 12-10-2018 AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 2.7E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.7E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 2.7E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 2.7E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 2.7E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.7E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13630 09c5fc65e222d5ff575c04f1e1546a52 278 Pfam PF00106 short chain dehydrogenase 5 132 7.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_05335 3ef6e34e8a1e7d9ebf5b81fabd2b0920 166 Pfam PF04417 Protein of unknown function (DUF501) 26 148 4.8E-39 T 12-10-2018 IPR007511 Protein of unknown function DUF501 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 SMART SM00421 149 206 2.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 SMART SM00448 6 119 1.1E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 SUPERFAMILY SSF52172 6 132 5.83E-26 T 12-10-2018 IPR011006 CheY-like superfamily AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 Gene3D G3DSA:3.40.50.2300 5 102 6.7E-19 T 12-10-2018 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 Gene3D G3DSA:1.10.10.10 103 219 7.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 SUPERFAMILY SSF46894 143 213 1.29E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_07155 56d3a5eb65868ac702e987e4ae029226 220 Pfam PF00072 Response regulator receiver domain 8 119 1.2E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24895 124b618630077838261f4e9271580ebd 409 SUPERFAMILY SSF159501 9 404 2.09E-74 T 12-10-2018 AFR_24895 124b618630077838261f4e9271580ebd 409 Gene3D G3DSA:3.30.1870.10 58 128 1.8E-54 T 12-10-2018 AFR_24895 124b618630077838261f4e9271580ebd 409 Pfam PF05139 Erythromycin esterase 57 372 1.5E-54 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 AFR_24895 124b618630077838261f4e9271580ebd 409 Gene3D G3DSA:3.40.1660.10 14 368 1.8E-54 T 12-10-2018 AFR_24895 124b618630077838261f4e9271580ebd 409 Gene3D G3DSA:1.20.1440.30 129 273 1.8E-54 T 12-10-2018 AFR_39430 2f48369b76331e59706ecc2bf10658d5 328 Pfam PF00583 Acetyltransferase (GNAT) family 202 303 3.3E-7 T 12-10-2018 IPR000182 GNAT domain AFR_39430 2f48369b76331e59706ecc2bf10658d5 328 Gene3D G3DSA:3.40.630.30 1 325 2.5E-48 T 12-10-2018 AFR_39430 2f48369b76331e59706ecc2bf10658d5 328 SUPERFAMILY SSF55729 4 73 5.04E-6 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_39430 2f48369b76331e59706ecc2bf10658d5 328 SUPERFAMILY SSF55729 93 312 7.93E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 17 468 44.496 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 Gene3D G3DSA:3.40.640.10 154 330 9.2E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 Gene3D G3DSA:3.40.640.10 47 121 3.8E-31 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 Pfam PF00464 Serine hydroxymethyltransferase 20 121 2.9E-28 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 Pfam PF00464 Serine hydroxymethyltransferase 154 427 3.9E-93 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 Gene3D G3DSA:3.90.1150.10 331 435 9.2E-107 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 Gene3D G3DSA:3.90.1150.10 21 46 3.8E-31 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 266 282 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 PIRSF PIRSF000412 2 472 9.7E-159 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_03190 3d2578a93b52b20a8bf45aaa9d242ef3 473 SUPERFAMILY SSF53383 17 468 1.99E-142 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_24750 8dc59d45605c3c1ef1a780769e994cfb 133 Pfam PF00293 NUDIX domain 7 129 7.0E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_24750 8dc59d45605c3c1ef1a780769e994cfb 133 Gene3D G3DSA:3.90.79.10 1 131 3.9E-23 T 12-10-2018 AFR_24750 8dc59d45605c3c1ef1a780769e994cfb 133 SUPERFAMILY SSF55811 5 123 2.17E-21 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_24690 df4741ce4d9b352745cf11af21aad3d4 111 Gene3D G3DSA:1.10.10.10 1 109 2.3E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24690 df4741ce4d9b352745cf11af21aad3d4 111 SUPERFAMILY SSF46785 5 100 5.89E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24690 df4741ce4d9b352745cf11af21aad3d4 111 Pfam PF12840 Helix-turn-helix domain 10 66 2.8E-17 T 12-10-2018 AFR_24690 df4741ce4d9b352745cf11af21aad3d4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_24690 df4741ce4d9b352745cf11af21aad3d4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 1.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_24690 df4741ce4d9b352745cf11af21aad3d4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_24690 df4741ce4d9b352745cf11af21aad3d4 111 SMART SM00418 9 87 1.4E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_30910 77e1f0d48a2471917aad579696df3879 134 Gene3D G3DSA:2.10.150.10 1 128 6.7E-45 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30910 77e1f0d48a2471917aad579696df3879 134 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 30.645 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30910 77e1f0d48a2471917aad579696df3879 134 Pfam PF00699 Urease beta subunit 3 99 3.0E-40 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30910 77e1f0d48a2471917aad579696df3879 134 SUPERFAMILY SSF51278 1 121 5.76E-46 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_30910 77e1f0d48a2471917aad579696df3879 134 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 4.6E-40 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 Gene3D G3DSA:1.10.10.10 1 48 1.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 SMART SM00345 1 47 1.8E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 SMART SM00895 57 184 1.2E-17 T 12-10-2018 IPR011711 GntR, C-terminal AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 7 21 1.5E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 21 37 1.5E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 47 3.2E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 SUPERFAMILY SSF48008 53 191 1.26E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 SUPERFAMILY SSF46785 3 51 2.65E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 Pfam PF07729 FCD domain 57 182 2.0E-21 T 12-10-2018 IPR011711 GntR, C-terminal AFR_17575 025bdbc846a5bf9e04e01c77cf5df3f4 194 Gene3D G3DSA:1.20.120.530 51 194 5.4E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_01885 16a2b0084ee9fe4dd38b082635fdbebe 145 Gene3D G3DSA:3.30.565.10 1 145 4.3E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01885 16a2b0084ee9fe4dd38b082635fdbebe 145 Pfam PF13581 Histidine kinase-like ATPase domain 8 140 1.8E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_18590 cf38d807da6d2c6213347d07000716b6 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 169 193 8.1E-11 T 12-10-2018 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 8.1E-11 T 12-10-2018 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 8.1E-11 T 12-10-2018 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 406 425 8.1E-11 T 12-10-2018 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 8.1E-11 T 12-10-2018 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 Gene3D G3DSA:1.20.1250.20 270 508 6.0E-17 T 12-10-2018 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 SUPERFAMILY SSF103473 8 507 1.31E-74 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_18590 cf38d807da6d2c6213347d07000716b6 529 Pfam PF07690 Major Facilitator Superfamily 22 415 1.1E-55 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 Gene3D G3DSA:1.20.1720.10 17 260 1.1E-47 T 12-10-2018 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 ProSitePatterns PS00216 Sugar transport proteins signature 1. 74 90 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_18590 cf38d807da6d2c6213347d07000716b6 529 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 497 1.8E-78 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_22100 dbf5c150e05200bfa5570b7262446701 727 SMART SM00458 29 157 1.2E-23 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_22100 dbf5c150e05200bfa5570b7262446701 727 SUPERFAMILY SSF50370 29 156 2.8E-37 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_22100 dbf5c150e05200bfa5570b7262446701 727 Gene3D G3DSA:2.80.10.50 26 124 1.2E-26 T 12-10-2018 AFR_22100 dbf5c150e05200bfa5570b7262446701 727 Gene3D G3DSA:2.80.10.50 125 172 7.7E-10 T 12-10-2018 AFR_22100 dbf5c150e05200bfa5570b7262446701 727 Pfam PF00652 Ricin-type beta-trefoil lectin domain 31 154 4.6E-26 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_05935 8450b3c43d659f0809d4324ec9e9abb5 434 Pfam PF13360 PQQ-like domain 91 239 4.1E-13 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_05935 8450b3c43d659f0809d4324ec9e9abb5 434 SUPERFAMILY SSF50998 63 232 1.22E-11 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_05935 8450b3c43d659f0809d4324ec9e9abb5 434 SUPERFAMILY SSF50998 169 365 1.1E-8 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_05935 8450b3c43d659f0809d4324ec9e9abb5 434 Gene3D G3DSA:2.130.10.10 77 402 1.2E-19 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_06345 f0de271e335b54275ede5fdbaaaadcb0 119 SUPERFAMILY SSF54285 1 91 7.52E-26 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFR_06345 f0de271e335b54275ede5fdbaaaadcb0 119 Pfam PF02597 ThiS family 5 91 3.6E-19 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFR_06345 f0de271e335b54275ede5fdbaaaadcb0 119 Gene3D G3DSA:3.10.20.30 1 91 5.4E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_40290 b8a9412ab1e509304280457580ba78b2 467 Gene3D G3DSA:1.20.1250.20 11 385 4.8E-62 T 12-10-2018 AFR_40290 b8a9412ab1e509304280457580ba78b2 467 Pfam PF07690 Major Facilitator Superfamily 19 237 7.6E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_40290 b8a9412ab1e509304280457580ba78b2 467 SUPERFAMILY SSF103473 13 396 2.62E-65 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_40290 b8a9412ab1e509304280457580ba78b2 467 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_22950 6938165026bfff7052865ded3b65bcd5 284 Pfam PF13560 Helix-turn-helix domain 7 87 5.6E-16 T 12-10-2018 AFR_22950 6938165026bfff7052865ded3b65bcd5 284 SMART SM00530 11 84 1.9E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_22950 6938165026bfff7052865ded3b65bcd5 284 Gene3D G3DSA:3.30.450.180 109 282 1.1E-16 T 12-10-2018 AFR_22950 6938165026bfff7052865ded3b65bcd5 284 Gene3D G3DSA:1.10.260.40 4 85 1.6E-6 T 12-10-2018 AFR_22950 6938165026bfff7052865ded3b65bcd5 284 SUPERFAMILY SSF47413 32 80 5.04E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_01220 bcbf205069e1c7ff395f610ee14b3204 139 Gene3D G3DSA:3.30.565.10 9 137 5.3E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01220 bcbf205069e1c7ff395f610ee14b3204 139 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 134 2.2E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01220 bcbf205069e1c7ff395f610ee14b3204 139 SMART SM00387 40 139 1.5E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01220 bcbf205069e1c7ff395f610ee14b3204 139 SUPERFAMILY SSF55874 28 134 7.8E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_16410 6d0d9c59a611868fe2b701be3335bb6d 210 SMART SM00060 30 104 4.3 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_16410 6d0d9c59a611868fe2b701be3335bb6d 210 SMART SM00060 122 200 0.27 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_16410 6d0d9c59a611868fe2b701be3335bb6d 210 SUPERFAMILY SSF49265 30 184 7.9E-10 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_16410 6d0d9c59a611868fe2b701be3335bb6d 210 Gene3D G3DSA:2.60.40.10 121 207 3.8E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_16410 6d0d9c59a611868fe2b701be3335bb6d 210 Gene3D G3DSA:2.60.40.10 28 111 1.0E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_22225 c939cecc32ea0176fea3f4729fa2d279 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 142 3.5E-11 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_22225 c939cecc32ea0176fea3f4729fa2d279 146 Gene3D G3DSA:3.30.530.20 3 146 1.3E-15 T 12-10-2018 IPR023393 START-like domain superfamily AFR_22225 c939cecc32ea0176fea3f4729fa2d279 146 SUPERFAMILY SSF55961 5 143 2.95E-21 T 12-10-2018 AFR_32110 aa2c8355e20a919d8708f8918830fa63 186 Pfam PF03713 Domain of unknown function (DUF305) 66 178 3.6E-13 T 12-10-2018 IPR005183 Domain of unknown function DUF305 AFR_32110 aa2c8355e20a919d8708f8918830fa63 186 Gene3D G3DSA:1.20.1260.10 40 181 1.9E-15 T 12-10-2018 IPR012347 Ferritin-like AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 Gene3D G3DSA:3.30.428.10 41 172 4.3E-48 T 12-10-2018 IPR036265 HIT-like superfamily AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 182 336 6.1E-50 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 149 166 - T 12-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 SUPERFAMILY SSF54197 182 336 8.17E-49 T 12-10-2018 IPR036265 HIT-like superfamily AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 PIRSF PIRSF000808 2 338 1.0E-104 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 6 174 9.5E-58 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 SUPERFAMILY SSF54197 6 174 5.26E-62 T 12-10-2018 IPR036265 HIT-like superfamily AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 Gene3D G3DSA:3.30.428.10 174 339 4.2E-62 T 12-10-2018 IPR036265 HIT-like superfamily AFR_14975 c7d9003294a2a39123ff20c3a592f500 339 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 6 335 2.9E-125 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 233 248 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 SMART SM01230 105 360 1.1E-121 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 SUPERFAMILY SSF54368 8 102 8.24E-28 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 SUPERFAMILY SSF55931 107 448 8.34E-114 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 Gene3D G3DSA:3.30.590.10 108 449 1.8E-117 T 12-10-2018 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 Gene3D G3DSA:3.10.20.70 2 107 1.1E-32 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 Pfam PF00120 Glutamine synthetase, catalytic domain 106 446 1.5E-121 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFR_09045 41eb1382de48a3e521edd54c2097772e 450 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 1.5E-25 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFR_41050 b9e5b73225c2803bec063b8e92b0fae4 415 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 59 204 3.2E-9 T 12-10-2018 AFR_41050 b9e5b73225c2803bec063b8e92b0fae4 415 Pfam PF13224 Domain of unknown function (DUF4032) 240 398 7.6E-63 T 12-10-2018 IPR025111 Domain of unknown function DUF4032 AFR_41050 b9e5b73225c2803bec063b8e92b0fae4 415 SUPERFAMILY SSF56112 47 182 3.57E-7 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_28520 b220382040b2163828d742233c6af6dc 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 150 4.0E-28 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_28520 b220382040b2163828d742233c6af6dc 162 SUPERFAMILY SSF55961 9 155 6.6E-43 T 12-10-2018 AFR_28520 b220382040b2163828d742233c6af6dc 162 Gene3D G3DSA:3.30.530.20 2 158 1.2E-43 T 12-10-2018 IPR023393 START-like domain superfamily AFR_08080 e2c14e4cb55ded8745dee407514f823d 293 Pfam PF00950 ABC 3 transport family 5 260 2.6E-62 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFR_08080 e2c14e4cb55ded8745dee407514f823d 293 Gene3D G3DSA:1.10.3470.10 38 272 2.9E-7 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_08080 e2c14e4cb55ded8745dee407514f823d 293 SUPERFAMILY SSF81345 3 259 3.79E-32 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_34180 f5904bfaf03faf4b47b909a3b6c1a42f 302 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_34180 f5904bfaf03faf4b47b909a3b6c1a42f 302 Pfam PF00005 ABC transporter 21 158 2.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_34180 f5904bfaf03faf4b47b909a3b6c1a42f 302 SUPERFAMILY SSF52540 4 229 4.89E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34180 f5904bfaf03faf4b47b909a3b6c1a42f 302 Gene3D G3DSA:3.40.50.300 1 228 2.1E-63 T 12-10-2018 AFR_34180 f5904bfaf03faf4b47b909a3b6c1a42f 302 SMART SM00382 29 206 7.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33140 143b5e686419a99de289e329b16f2a4d 548 Pfam PF00128 Alpha amylase, catalytic domain 47 398 5.9E-75 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_33140 143b5e686419a99de289e329b16f2a4d 548 Gene3D G3DSA:3.90.400.10 124 200 1.6E-144 T 12-10-2018 AFR_33140 143b5e686419a99de289e329b16f2a4d 548 Gene3D G3DSA:3.20.20.80 24 477 1.6E-144 T 12-10-2018 AFR_33140 143b5e686419a99de289e329b16f2a4d 548 SMART SM00642 32 423 1.8E-111 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_33140 143b5e686419a99de289e329b16f2a4d 548 SUPERFAMILY SSF51445 23 479 1.39E-119 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_20765 f7d416d5b701624824ff36b94d93d746 388 Gene3D G3DSA:3.40.50.720 2 133 6.8E-38 T 12-10-2018 AFR_20765 f7d416d5b701624824ff36b94d93d746 388 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 132 9.4E-29 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_20765 f7d416d5b701624824ff36b94d93d746 388 Gene3D G3DSA:3.30.360.10 134 387 1.6E-48 T 12-10-2018 AFR_20765 f7d416d5b701624824ff36b94d93d746 388 SUPERFAMILY SSF55347 137 303 3.27E-25 T 12-10-2018 AFR_20765 f7d416d5b701624824ff36b94d93d746 388 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 204 6.2E-5 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_20765 f7d416d5b701624824ff36b94d93d746 388 SUPERFAMILY SSF51735 3 163 2.12E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41920 b1d18d59270cfc30825a96cfe077be07 190 Gene3D G3DSA:1.20.120.450 4 165 1.8E-35 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_41920 b1d18d59270cfc30825a96cfe077be07 190 Pfam PF04978 Protein of unknown function (DUF664) 15 164 1.1E-43 T 12-10-2018 IPR007061 Protein of unknown function DUF664 AFR_41920 b1d18d59270cfc30825a96cfe077be07 190 SUPERFAMILY SSF109854 4 163 1.28E-35 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_33295 94faf5ee34b36552c2b158c9a53a9ac3 225 SUPERFAMILY SSF161098 5 216 1.83E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_33295 94faf5ee34b36552c2b158c9a53a9ac3 225 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 3 214 2.4E-73 T 12-10-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0016020|GO:0055085 AFR_33295 94faf5ee34b36552c2b158c9a53a9ac3 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 215 3.7E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_33295 94faf5ee34b36552c2b158c9a53a9ac3 225 Gene3D G3DSA:1.10.3720.10 1 221 2.2E-70 T 12-10-2018 IPR035906 MetI-like superfamily AFR_33295 94faf5ee34b36552c2b158c9a53a9ac3 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 15 217 9.4E-73 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 Gene3D G3DSA:3.40.50.300 927 1153 6.7E-52 T 12-10-2018 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 Gene3D G3DSA:3.40.50.300 309 553 3.8E-65 T 12-10-2018 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 ProSitePatterns PS00211 ABC transporters family signature. 1062 1076 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 Pfam PF00664 ABC transporter transmembrane region 47 259 1.4E-16 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 SUPERFAMILY SSF52540 930 1151 4.65E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 Gene3D G3DSA:1.20.1560.10 611 893 2.1E-11 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 SUPERFAMILY SSF52540 311 542 4.67E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 SUPERFAMILY SSF90123 17 313 7.32E-37 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 SMART SM00382 348 631 1.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 SMART SM00382 955 1134 5.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 SUPERFAMILY SSF90123 603 892 1.96E-14 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 Pfam PF00005 ABC transporter 947 1087 4.4E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 Gene3D G3DSA:1.20.1560.10 2 308 3.4E-33 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_25060 8ed7ba57e3aec79bb43507f203938690 1153 Pfam PF00005 ABC transporter 339 487 8.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_25245 4b74c81a6c946d5a10067d2ee971a456 264 Pfam PF14100 Methane oxygenase PmoA 2 263 5.0E-63 T 12-10-2018 IPR029475 Methane oxygenase PmoA AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 Pfam PF01019 Gamma-glutamyltranspeptidase 271 442 3.8E-27 T 12-10-2018 AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 Pfam PF01019 Gamma-glutamyltranspeptidase 2 228 4.9E-51 T 12-10-2018 AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 Gene3D G3DSA:3.60.20.40 276 445 9.9E-30 T 12-10-2018 AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 SUPERFAMILY SSF56235 1 444 3.86E-83 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 351 368 5.7E-28 T 12-10-2018 AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 276 294 5.7E-28 T 12-10-2018 AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 326 341 5.7E-28 T 12-10-2018 AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 9 34 5.7E-28 T 12-10-2018 AFR_04185 b2280b853e98b124e03b3632bec8a70a 449 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 298 316 5.7E-28 T 12-10-2018 AFR_06750 754debdefcd1f54a9b4b5b6fafda570b 425 SUPERFAMILY SSF141523 262 383 2.75E-30 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_06750 754debdefcd1f54a9b4b5b6fafda570b 425 Pfam PF03734 L,D-transpeptidase catalytic domain 266 383 1.9E-17 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_06750 754debdefcd1f54a9b4b5b6fafda570b 425 Gene3D G3DSA:2.40.440.10 260 397 1.3E-86 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_06750 754debdefcd1f54a9b4b5b6fafda570b 425 Gene3D G3DSA:2.60.40.3780 61 153 5.9E-19 T 12-10-2018 AFR_06750 754debdefcd1f54a9b4b5b6fafda570b 425 Gene3D G3DSA:2.60.40.3710 166 409 1.3E-86 T 12-10-2018 AFR_27125 efe0e3ca9ad9186e45b0f2fb5a28b8d9 138 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 7 131 2.3E-9 T 12-10-2018 IPR028973 PhnB-like AFR_27125 efe0e3ca9ad9186e45b0f2fb5a28b8d9 138 Gene3D G3DSA:3.10.180.10 10 137 6.5E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_27125 efe0e3ca9ad9186e45b0f2fb5a28b8d9 138 SUPERFAMILY SSF54593 1 132 1.88E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_04090 5b01c8c01b76df3e9dc889cd75961614 378 SUPERFAMILY SSF53335 153 279 6.91E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_04090 5b01c8c01b76df3e9dc889cd75961614 378 Gene3D G3DSA:3.40.50.150 145 323 7.8E-13 T 12-10-2018 AFR_04090 5b01c8c01b76df3e9dc889cd75961614 378 Pfam PF13679 Methyltransferase domain 148 283 6.4E-29 T 12-10-2018 IPR025714 Methyltransferase domain AFR_34460 61789d1ff571b8bb8c3edbe292989a6a 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 1.7E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_34460 61789d1ff571b8bb8c3edbe292989a6a 180 SUPERFAMILY SSF48498 77 179 1.91E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_34460 61789d1ff571b8bb8c3edbe292989a6a 180 Gene3D G3DSA:1.10.357.10 1 180 1.0E-53 T 12-10-2018 AFR_34460 61789d1ff571b8bb8c3edbe292989a6a 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_34460 61789d1ff571b8bb8c3edbe292989a6a 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 7.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_34460 61789d1ff571b8bb8c3edbe292989a6a 180 SUPERFAMILY SSF46689 2 78 1.95E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_16765 70b04f5c8b6a76f0ca64ba2a1fb5cbae 236 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 102 3.9E-12 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_16765 70b04f5c8b6a76f0ca64ba2a1fb5cbae 236 SUPERFAMILY SSF109854 4 126 4.73E-19 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_16765 70b04f5c8b6a76f0ca64ba2a1fb5cbae 236 Gene3D G3DSA:1.20.120.450 2 158 4.4E-13 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_16765 70b04f5c8b6a76f0ca64ba2a1fb5cbae 236 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 217 3.8E-23 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 Gene3D G3DSA:2.60.120.200 439 639 1.3E-65 T 12-10-2018 AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 Gene3D G3DSA:2.60.40.290 28 137 7.9E-36 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 Pfam PF00553 Cellulose binding domain 35 134 9.3E-32 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 Gene3D G3DSA:2.115.10.20 144 431 1.6E-68 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 SUPERFAMILY SSF75005 148 435 5.37E-62 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 SUPERFAMILY SSF49384 31 136 2.58E-32 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 SUPERFAMILY SSF49899 442 639 3.96E-30 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 SMART SM00637 35 134 1.0E-45 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14905 c6debd1c4f4f48ab37ccaa954d2a5080 642 Pfam PF04616 Glycosyl hydrolases family 43 148 413 3.6E-34 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_05450 5513005dcd30c6b3eeea4fd8f2c0f75c 474 SMART SM00880 212 455 1.4E-60 T 12-10-2018 IPR007899 CHAD domain AFR_05450 5513005dcd30c6b3eeea4fd8f2c0f75c 474 Pfam PF05235 CHAD domain 212 427 1.2E-52 T 12-10-2018 IPR007899 CHAD domain AFR_05450 5513005dcd30c6b3eeea4fd8f2c0f75c 474 Gene3D G3DSA:1.40.20.10 202 471 1.1E-57 T 12-10-2018 IPR038186 CHAD domain superfamily AFR_05450 5513005dcd30c6b3eeea4fd8f2c0f75c 474 SMART SM01118 4 195 1.7E-16 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFR_05450 5513005dcd30c6b3eeea4fd8f2c0f75c 474 Pfam PF01928 CYTH domain 5 175 1.7E-17 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFR_05450 5513005dcd30c6b3eeea4fd8f2c0f75c 474 SUPERFAMILY SSF55154 1 203 6.32E-44 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 AFR_05450 5513005dcd30c6b3eeea4fd8f2c0f75c 474 Gene3D G3DSA:2.40.320.10 1 192 9.3E-21 T 12-10-2018 AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 61 127 2.5E-27 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 52 3.1E-16 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 Gene3D G3DSA:1.20.5.710 4 56 6.0E-18 T 12-10-2018 AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 SUPERFAMILY SSF48300 4 52 4.97E-13 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 SUPERFAMILY SSF54736 57 127 1.13E-22 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 Gene3D G3DSA:3.30.1390.10 57 127 3.0E-28 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 127 23.388 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 62 102 2.0E-9 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04455 9e8b77300f0a3597438d7e7e99079598 127 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 127 1.0E-44 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_17720 3db49ef0015b4df10172c55edf5189f7 541 SUPERFAMILY SSF51338 9 539 5.44E-19 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_17720 3db49ef0015b4df10172c55edf5189f7 541 Gene3D G3DSA:2.30.40.10 13 515 4.3E-126 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_17720 3db49ef0015b4df10172c55edf5189f7 541 Pfam PF07969 Amidohydrolase family 47 538 6.0E-88 T 12-10-2018 IPR013108 Amidohydrolase 3 AFR_17720 3db49ef0015b4df10172c55edf5189f7 541 SUPERFAMILY SSF51556 58 495 4.0E-31 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_17720 3db49ef0015b4df10172c55edf5189f7 541 Gene3D G3DSA:3.20.20.140 59 497 4.3E-126 T 12-10-2018 AFR_17720 3db49ef0015b4df10172c55edf5189f7 541 Gene3D G3DSA:3.10.310.70 77 195 4.3E-126 T 12-10-2018 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 4.3E-242 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 Pfam PF00920 Dehydratase family 34 609 2.4E-214 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 Gene3D G3DSA:3.50.30.80 424 575 1.7E-54 T 12-10-2018 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 SUPERFAMILY SSF52016 424 612 6.91E-60 T 12-10-2018 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.925 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 SUPERFAMILY SSF143975 4 423 6.67E-131 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_36905 179e470bf9665c88a09edc5aaf6f1db0 615 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 155 6.8E-26 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 SUPERFAMILY SSF88659 85 159 6.73E-19 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 Pfam PF08281 Sigma-70, region 4 100 153 2.8E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 Pfam PF04542 Sigma-70 region 2 17 76 6.4E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 Gene3D G3DSA:1.10.10.10 75 161 6.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 159 4.3E-49 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 Gene3D G3DSA:1.10.1740.10 3 71 1.3E-7 T 12-10-2018 AFR_02180 2ca860ea6bd2b49c759be197bb8e04fd 170 SUPERFAMILY SSF88946 6 79 1.1E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_09140 6960222980ea9e7bb41cae4fa8561bc0 110 Gene3D G3DSA:1.10.287.1060 1 96 6.9E-5 T 12-10-2018 AFR_09140 6960222980ea9e7bb41cae4fa8561bc0 110 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 4 97 2.1E-5 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 AFR_05265 be9a04c0a5564db5213017367cbe899e 477 SMART SM00108 367 476 2.1E-8 T 12-10-2018 IPR001480 Bulb-type lectin domain AFR_05265 be9a04c0a5564db5213017367cbe899e 477 Gene3D G3DSA:2.90.10.10 363 476 1.2E-26 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_05265 be9a04c0a5564db5213017367cbe899e 477 Pfam PF01453 D-mannose binding lectin 416 476 9.4E-13 T 12-10-2018 IPR001480 Bulb-type lectin domain AFR_05265 be9a04c0a5564db5213017367cbe899e 477 SUPERFAMILY SSF51445 58 355 4.35E-40 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_05265 be9a04c0a5564db5213017367cbe899e 477 Gene3D G3DSA:3.20.20.80 58 362 4.0E-43 T 12-10-2018 AFR_05265 be9a04c0a5564db5213017367cbe899e 477 SUPERFAMILY SSF51110 417 476 2.88E-14 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_34205 1d2e42b8fb1bba4cde3c4998d3e6a6a3 277 Pfam PF02517 CAAX protease self-immunity 108 196 1.1E-15 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFR_34205 1d2e42b8fb1bba4cde3c4998d3e6a6a3 277 SUPERFAMILY SSF103473 11 259 4.19E-6 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_18410 2e399d8d83cbb0ee6ced7dd82aa8900d 539 Pfam PF07819 PGAP1-like protein 132 196 1.8E-7 T 12-10-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 AFR_18410 2e399d8d83cbb0ee6ced7dd82aa8900d 539 SUPERFAMILY SSF53474 142 291 6.29E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18410 2e399d8d83cbb0ee6ced7dd82aa8900d 539 Gene3D G3DSA:3.40.50.1820 7 303 1.1E-18 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_42705 c3a40e471a00beb57c7bc63f057e713e 160 Gene3D G3DSA:3.40.630.30 2 158 2.0E-40 T 12-10-2018 AFR_42705 c3a40e471a00beb57c7bc63f057e713e 160 SUPERFAMILY SSF55729 3 128 1.52E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_42705 c3a40e471a00beb57c7bc63f057e713e 160 Pfam PF00583 Acetyltransferase (GNAT) family 14 122 2.0E-11 T 12-10-2018 IPR000182 GNAT domain AFR_21120 3326c983ab8ca5f6ee094035acd16ef9 287 SUPERFAMILY SSF53850 87 285 1.34E-24 T 12-10-2018 AFR_21120 3326c983ab8ca5f6ee094035acd16ef9 287 Gene3D G3DSA:1.10.10.10 1 87 2.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21120 3326c983ab8ca5f6ee094035acd16ef9 287 Pfam PF03466 LysR substrate binding domain 86 286 2.0E-26 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_21120 3326c983ab8ca5f6ee094035acd16ef9 287 SUPERFAMILY SSF46785 1 107 1.37E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_21120 3326c983ab8ca5f6ee094035acd16ef9 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.0E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_21120 3326c983ab8ca5f6ee094035acd16ef9 287 Gene3D G3DSA:3.40.190.290 90 286 3.6E-23 T 12-10-2018 AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 SUPERFAMILY SSF51735 1 256 3.15E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 Gene3D G3DSA:3.40.50.720 1 250 2.8E-62 T 12-10-2018 AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 120 148 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 Pfam PF00106 short chain dehydrogenase 2 172 1.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 61 72 5.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 171 5.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 107 123 5.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 152 5.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 152 2.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 113 121 2.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24340 633656d06a52a7b4c463f5ac75c759ca 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 61 72 2.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 Gene3D G3DSA:3.40.50.720 1 257 6.9E-68 T 12-10-2018 AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 9.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 9.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 7.5E-44 T 12-10-2018 AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_20185 9884d4518be5929bb0b09ed03c3b07b1 258 SUPERFAMILY SSF51735 1 253 4.0E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 25 177 1.0E-49 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 178 218 1.8E-10 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 SUPERFAMILY SSF88697 236 292 3.43E-10 T 12-10-2018 IPR015947 PUA-like superfamily AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 216 2.8E-67 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 Gene3D G3DSA:3.30.2350.10 5 224 1.5E-86 T 12-10-2018 AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 236 290 3.5E-16 T 12-10-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 3 290 17.265 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 SUPERFAMILY SSF55120 3 223 2.88E-71 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_35935 f8cdc8b696b7f82f5d535c050dd26513 293 Gene3D G3DSA:2.30.130.10 228 290 5.2E-13 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFR_37010 24b5c9f7027e1d83fac9343af5b2453c 344 Gene3D G3DSA:3.20.20.210 85 344 3.1E-23 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFR_37010 24b5c9f7027e1d83fac9343af5b2453c 344 SUPERFAMILY SSF51726 89 342 1.16E-23 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFR_37010 24b5c9f7027e1d83fac9343af5b2453c 344 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 24 338 6.5E-9 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 369 419 1.9E-11 T 12-10-2018 IPR001434 Domain of unknown function DUF11 AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Gene3D G3DSA:2.60.40.10 908 998 4.6E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Gene3D G3DSA:2.60.40.10 820 907 7.3E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Gene3D G3DSA:2.60.40.10 1632 1724 1.7E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Pfam PF01345 Domain of unknown function DUF11 369 474 5.9E-10 T 12-10-2018 IPR001434 Domain of unknown function DUF11 AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Gene3D G3DSA:2.60.40.3440 1108 1180 4.1E-5 T 12-10-2018 AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Gene3D G3DSA:2.60.40.3440 731 816 1.7E-7 T 12-10-2018 AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Gene3D G3DSA:2.60.40.3440 625 728 8.3E-6 T 12-10-2018 AFR_40880 722cc21258cc2c4c18ac4da2f7009dcf 1792 Gene3D G3DSA:2.60.40.3440 1007 1092 6.0E-6 T 12-10-2018 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 SMART SM00448 2 115 1.6E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 Pfam PF00072 Response regulator receiver domain 5 115 5.5E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 2.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 7.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 7.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 7.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 SUPERFAMILY SSF46894 132 201 8.84E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 SUPERFAMILY SSF52172 1 128 1.85E-29 T 12-10-2018 IPR011006 CheY-like superfamily AFR_21280 388b048e10d94d646fc46c8154896f5a 203 Gene3D G3DSA:3.40.50.12740 2 201 9.6E-57 T 12-10-2018 AFR_21280 388b048e10d94d646fc46c8154896f5a 203 SMART SM00421 138 195 5.9E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_35260 dd345ccf87bfd96ab471d73720627456 425 Pfam PF01938 TRAM domain 5 64 2.9E-14 T 12-10-2018 IPR002792 TRAM domain AFR_35260 dd345ccf87bfd96ab471d73720627456 425 Gene3D G3DSA:3.40.1350.30 140 257 6.5E-61 T 12-10-2018 AFR_35260 dd345ccf87bfd96ab471d73720627456 425 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 406 416 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site AFR_35260 dd345ccf87bfd96ab471d73720627456 425 SUPERFAMILY SSF50249 10 71 2.8E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_35260 dd345ccf87bfd96ab471d73720627456 425 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 349 423 3.8E-8 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 AFR_35260 dd345ccf87bfd96ab471d73720627456 425 SUPERFAMILY SSF53335 72 423 2.32E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_35260 dd345ccf87bfd96ab471d73720627456 425 Gene3D G3DSA:3.40.50.150 87 418 6.5E-61 T 12-10-2018 AFR_35260 dd345ccf87bfd96ab471d73720627456 425 Gene3D G3DSA:2.40.50.140 3 83 1.7E-18 T 12-10-2018 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 SMART SM00448 1 120 4.1E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 SUPERFAMILY SSF52172 1 176 5.88E-20 T 12-10-2018 IPR011006 CheY-like superfamily AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 SMART SM00421 148 205 3.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 Gene3D G3DSA:3.40.50.12740 1 207 6.1E-44 T 12-10-2018 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 Pfam PF00072 Response regulator receiver domain 3 108 2.3E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 196 4.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 6.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 6.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_18575 783fd0822de6fea28d0e83c758b89b28 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 6.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_07170 dad39f5b206c4b6f91f1ebdb46d721b1 305 SUPERFAMILY SSF56112 47 276 2.04E-22 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_07170 dad39f5b206c4b6f91f1ebdb46d721b1 305 Pfam PF01636 Phosphotransferase enzyme family 50 252 6.8E-13 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_12045 5cbbab048d95dd1cdd245e6505a29a16 381 Pfam PF01882 Protein of unknown function DUF58 189 275 4.8E-20 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_30030 6d9f5ac3b00ba64fdcacc1515141bf1a 163 SUPERFAMILY SSF50118 56 158 1.29E-11 T 12-10-2018 AFR_30030 6d9f5ac3b00ba64fdcacc1515141bf1a 163 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 58 157 2.2E-11 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFR_20630 66237f7a21107c242866408b1944929c 256 SUPERFAMILY SSF53213 4 254 1.18E-76 T 12-10-2018 AFR_20630 66237f7a21107c242866408b1944929c 256 Gene3D G3DSA:3.40.830.10 1 253 6.1E-71 T 12-10-2018 AFR_20630 66237f7a21107c242866408b1944929c 256 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 32 232 1.0E-35 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFR_20630 66237f7a21107c242866408b1944929c 256 PIRSF PIRSF006157 1 256 8.5E-76 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 AFR_07245 4191ed2933435bb95fb267583328d671 238 Gene3D G3DSA:1.25.40.10 26 233 6.7E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_12000 880e054e4ab6a26aff6a4778d7c08227 228 Pfam PF06197 Protein of unknown function (DUF998) 14 207 3.2E-16 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_10820 ad5b11becc0ce8b93ef275242e9c079e 275 SUPERFAMILY SSF49899 28 273 1.11E-69 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_10820 ad5b11becc0ce8b93ef275242e9c079e 275 Gene3D G3DSA:2.60.120.200 32 275 2.1E-81 T 12-10-2018 AFR_10820 ad5b11becc0ce8b93ef275242e9c079e 275 Pfam PF00722 Glycosyl hydrolases family 16 69 271 2.2E-36 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_27695 323825cd5d351b9b48e74526a2718861 449 Gene3D G3DSA:3.50.50.100 1 396 2.4E-108 T 12-10-2018 AFR_27695 323825cd5d351b9b48e74526a2718861 449 SUPERFAMILY SSF51905 1 332 1.65E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27695 323825cd5d351b9b48e74526a2718861 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 3.9E-5 T 12-10-2018 AFR_27695 323825cd5d351b9b48e74526a2718861 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 3.9E-5 T 12-10-2018 AFR_27695 323825cd5d351b9b48e74526a2718861 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 3.9E-5 T 12-10-2018 AFR_27695 323825cd5d351b9b48e74526a2718861 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 322 1.1E-47 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_27695 323825cd5d351b9b48e74526a2718861 449 SUPERFAMILY SSF51905 155 401 2.69E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_32485 a96c502393258960631b0c498f664443 312 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 311 1.9E-93 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFR_32485 a96c502393258960631b0c498f664443 312 SUPERFAMILY SSF53271 69 304 1.06E-45 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_32485 a96c502393258960631b0c498f664443 312 Gene3D G3DSA:3.40.50.2020 147 288 1.3E-97 T 12-10-2018 AFR_32485 a96c502393258960631b0c498f664443 312 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 120 1.7E-38 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFR_32485 a96c502393258960631b0c498f664443 312 Gene3D G3DSA:3.40.50.2020 7 300 1.3E-97 T 12-10-2018 AFR_32485 a96c502393258960631b0c498f664443 312 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 311 2.1E-18 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFR_32485 a96c502393258960631b0c498f664443 312 SMART SM01400 4 120 1.6E-61 T 12-10-2018 AFR_22315 155989a849fc041d9ed8e6caf3e5f310 243 SMART SM00382 37 204 1.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22315 155989a849fc041d9ed8e6caf3e5f310 243 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_22315 155989a849fc041d9ed8e6caf3e5f310 243 SUPERFAMILY SSF52540 13 208 3.97E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22315 155989a849fc041d9ed8e6caf3e5f310 243 Pfam PF00005 ABC transporter 28 154 1.8E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_22315 155989a849fc041d9ed8e6caf3e5f310 243 Gene3D G3DSA:3.40.50.300 2 212 3.9E-55 T 12-10-2018 AFR_12695 80c2590e43eae875374361fc9e28e8bd 303 Gene3D G3DSA:3.40.50.720 35 293 1.3E-83 T 12-10-2018 AFR_12695 80c2590e43eae875374361fc9e28e8bd 303 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 269 7.4E-44 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFR_12695 80c2590e43eae875374361fc9e28e8bd 303 SUPERFAMILY SSF51735 105 270 6.61E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12695 80c2590e43eae875374361fc9e28e8bd 303 Gene3D G3DSA:3.40.50.720 101 268 1.3E-83 T 12-10-2018 AFR_12695 80c2590e43eae875374361fc9e28e8bd 303 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 36 295 9.2E-26 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFR_12695 80c2590e43eae875374361fc9e28e8bd 303 SUPERFAMILY SSF52283 1 137 2.46E-28 T 12-10-2018 AFR_13980 ffc310f180a1aca7cee7c05d227c7eea 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 436 1.2E-83 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFR_13980 ffc310f180a1aca7cee7c05d227c7eea 530 PIRSF PIRSF002741 1 525 7.5E-112 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFR_13980 ffc310f180a1aca7cee7c05d227c7eea 530 SUPERFAMILY SSF53850 35 512 3.8E-122 T 12-10-2018 AFR_13980 ffc310f180a1aca7cee7c05d227c7eea 530 Gene3D G3DSA:3.10.105.10 272 491 1.2E-136 T 12-10-2018 AFR_13980 ffc310f180a1aca7cee7c05d227c7eea 530 Gene3D G3DSA:3.90.76.10 65 180 1.2E-136 T 12-10-2018 AFR_13980 ffc310f180a1aca7cee7c05d227c7eea 530 Gene3D G3DSA:3.40.190.10 50 505 1.2E-136 T 12-10-2018 AFR_38440 425952b58056a09d73c3798873085bd4 352 Gene3D G3DSA:1.10.8.450 259 297 6.0E-42 T 12-10-2018 AFR_38440 425952b58056a09d73c3798873085bd4 352 Gene3D G3DSA:3.40.190.10 40 316 6.0E-42 T 12-10-2018 AFR_38440 425952b58056a09d73c3798873085bd4 352 Pfam PF13379 NMT1-like family 36 273 3.6E-33 T 12-10-2018 AFR_38440 425952b58056a09d73c3798873085bd4 352 SMART SM00062 39 264 0.0058 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_38440 425952b58056a09d73c3798873085bd4 352 Gene3D G3DSA:3.40.190.10 120 223 6.0E-42 T 12-10-2018 AFR_38440 425952b58056a09d73c3798873085bd4 352 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 40 332 5.9E-62 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 AFR_38440 425952b58056a09d73c3798873085bd4 352 SUPERFAMILY SSF53850 38 269 5.23E-40 T 12-10-2018 AFR_32905 740c52cd5f368b05283c3bf131b5d542 311 PRINTS PR00990 Ribokinase signature 181 196 1.1E-5 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_32905 740c52cd5f368b05283c3bf131b5d542 311 PRINTS PR00990 Ribokinase signature 218 229 1.1E-5 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_32905 740c52cd5f368b05283c3bf131b5d542 311 PRINTS PR00990 Ribokinase signature 28 47 1.1E-5 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_32905 740c52cd5f368b05283c3bf131b5d542 311 Pfam PF00294 pfkB family carbohydrate kinase 1 295 1.6E-48 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_32905 740c52cd5f368b05283c3bf131b5d542 311 Gene3D G3DSA:3.40.1190.20 1 310 1.7E-84 T 12-10-2018 IPR029056 Ribokinase-like AFR_32905 740c52cd5f368b05283c3bf131b5d542 311 SUPERFAMILY SSF53613 1 302 2.34E-70 T 12-10-2018 IPR029056 Ribokinase-like AFR_32905 740c52cd5f368b05283c3bf131b5d542 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_33905 bafca738131f31dae71e0d517b73bc63 177 Pfam PF12079 Protein of unknown function (DUF3558) 17 119 3.7E-12 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 AFR_42830 84898030f7ad9ea73c501c37503d7b1b 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 2 93 1.2E-23 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42830 84898030f7ad9ea73c501c37503d7b1b 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.864 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFR_42830 84898030f7ad9ea73c501c37503d7b1b 96 Gene3D G3DSA:3.30.70.60 1 96 2.6E-29 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AFR_42830 84898030f7ad9ea73c501c37503d7b1b 96 Pfam PF01250 Ribosomal protein S6 3 92 3.0E-26 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42830 84898030f7ad9ea73c501c37503d7b1b 96 SUPERFAMILY SSF54995 2 94 5.1E-30 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_25595 55b7a726ba7aa4544575ad936ddbdec1 348 Pfam PF00990 Diguanylate cyclase, GGDEF domain 168 320 3.2E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_25595 55b7a726ba7aa4544575ad936ddbdec1 348 SMART SM00267 157 325 2.4E-53 T 12-10-2018 IPR000160 GGDEF domain AFR_25595 55b7a726ba7aa4544575ad936ddbdec1 348 SUPERFAMILY SSF55073 173 324 1.26E-40 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_25595 55b7a726ba7aa4544575ad936ddbdec1 348 Gene3D G3DSA:3.30.70.270 162 330 3.1E-49 T 12-10-2018 AFR_25595 55b7a726ba7aa4544575ad936ddbdec1 348 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 164 324 5.1E-42 T 12-10-2018 IPR000160 GGDEF domain AFR_36785 04fcc28b82e2122ad8ff8b80a0d63e8f 326 SUPERFAMILY SSF53300 82 286 3.89E-27 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_36785 04fcc28b82e2122ad8ff8b80a0d63e8f 326 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 9.9E-9 T 12-10-2018 IPR024163 Aerotolerance regulator, N-terminal AFR_36785 04fcc28b82e2122ad8ff8b80a0d63e8f 326 Pfam PF13519 von Willebrand factor type A domain 88 202 3.8E-18 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_36785 04fcc28b82e2122ad8ff8b80a0d63e8f 326 Gene3D G3DSA:3.40.50.410 87 288 1.4E-44 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_36785 04fcc28b82e2122ad8ff8b80a0d63e8f 326 SMART SM00327 85 264 5.3E-17 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_01180 8c84a10af4048014809726c4de7d6d48 421 Gene3D G3DSA:2.80.10.50 279 420 6.7E-40 T 12-10-2018 AFR_01180 8c84a10af4048014809726c4de7d6d48 421 SUPERFAMILY SSF50370 281 419 6.75E-40 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_01180 8c84a10af4048014809726c4de7d6d48 421 Pfam PF06283 Trehalose utilisation 43 248 5.2E-30 T 12-10-2018 IPR029010 ThuA-like domain AFR_01180 8c84a10af4048014809726c4de7d6d48 421 SUPERFAMILY SSF52317 36 275 2.29E-25 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_01180 8c84a10af4048014809726c4de7d6d48 421 Gene3D G3DSA:3.40.50.880 24 277 1.0E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_01180 8c84a10af4048014809726c4de7d6d48 421 Pfam PF00652 Ricin-type beta-trefoil lectin domain 283 416 1.7E-20 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_01180 8c84a10af4048014809726c4de7d6d48 421 SMART SM00458 280 419 1.6E-11 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_42490 8003ca37c64896d30163d6039666b4c6 138 Pfam PF04341 Protein of unknown function, DUF485 15 102 4.1E-31 T 12-10-2018 IPR007436 Protein of unknown function DUF485 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 301 317 2.0E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 301 2.0E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 Gene3D G3DSA:1.10.10.60 215 321 4.4E-27 T 12-10-2018 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 271 313 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 SMART SM00342 234 317 5.4E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 SUPERFAMILY SSF46689 220 268 2.78E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 SUPERFAMILY SSF46689 270 319 1.08E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 Pfam PF12852 Cupin 20 203 4.3E-35 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFR_12180 bc019a241e71143b6ad0d1cbc03eff42 327 Pfam PF12833 Helix-turn-helix domain 240 318 2.4E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_07180 834204ae4ac1faaed4f7edb8b6e29c6b 278 Pfam PF01061 ABC-2 type transporter 38 244 4.3E-34 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_07180 834204ae4ac1faaed4f7edb8b6e29c6b 278 PIRSF PIRSF006648 7 278 4.7E-70 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_09730 3e7f3f83eca17d5c348f82a552178c0b 222 Gene3D G3DSA:1.20.120.1760 31 221 3.4E-27 T 12-10-2018 AFR_09730 3e7f3f83eca17d5c348f82a552178c0b 222 Pfam PF01066 CDP-alcohol phosphatidyltransferase 47 111 3.2E-8 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_11780 0409f78334b87a8018595c420f0991eb 444 Pfam PF15892 BNR repeat-containing family member 58 352 4.9E-28 T 12-10-2018 IPR039469 BNR repeat-containing family member AFR_11780 0409f78334b87a8018595c420f0991eb 444 SUPERFAMILY SSF50939 90 202 3.08E-9 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 AFR_11780 0409f78334b87a8018595c420f0991eb 444 Gene3D G3DSA:2.120.10.10 44 210 1.0E-6 T 12-10-2018 AFR_24090 080ca44bd3395b08feca9cf6f45d493a 292 Gene3D G3DSA:1.10.260.40 8 72 9.2E-6 T 12-10-2018 AFR_24090 080ca44bd3395b08feca9cf6f45d493a 292 SUPERFAMILY SSF47413 13 70 1.0E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_24090 080ca44bd3395b08feca9cf6f45d493a 292 Pfam PF13560 Helix-turn-helix domain 16 78 2.6E-11 T 12-10-2018 AFR_28955 183aad3d5580077f33e725cda0a88878 713 SUPERFAMILY SSF55874 604 706 6.3E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28955 183aad3d5580077f33e725cda0a88878 713 Pfam PF01590 GAF domain 39 169 3.8E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28955 183aad3d5580077f33e725cda0a88878 713 Pfam PF01590 GAF domain 367 495 9.1E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28955 183aad3d5580077f33e725cda0a88878 713 Pfam PF01590 GAF domain 203 334 2.0E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28955 183aad3d5580077f33e725cda0a88878 713 Pfam PF07730 Histidine kinase 519 583 7.2E-7 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_28955 183aad3d5580077f33e725cda0a88878 713 Gene3D G3DSA:3.30.450.40 19 177 3.4E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28955 183aad3d5580077f33e725cda0a88878 713 Gene3D G3DSA:3.30.450.40 343 508 7.3E-17 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28955 183aad3d5580077f33e725cda0a88878 713 Gene3D G3DSA:3.30.450.40 182 342 1.6E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_28955 183aad3d5580077f33e725cda0a88878 713 SUPERFAMILY SSF55781 367 507 3.11E-14 T 12-10-2018 AFR_28955 183aad3d5580077f33e725cda0a88878 713 SUPERFAMILY SSF55781 38 169 3.93E-15 T 12-10-2018 AFR_28955 183aad3d5580077f33e725cda0a88878 713 Gene3D G3DSA:3.30.565.10 585 707 7.6E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28955 183aad3d5580077f33e725cda0a88878 713 SMART SM00387 619 709 1.1E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28955 183aad3d5580077f33e725cda0a88878 713 SUPERFAMILY SSF55781 203 345 2.13E-18 T 12-10-2018 AFR_28955 183aad3d5580077f33e725cda0a88878 713 SMART SM00065 365 505 4.1E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28955 183aad3d5580077f33e725cda0a88878 713 SMART SM00065 200 344 1.1E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_28955 183aad3d5580077f33e725cda0a88878 713 SMART SM00065 37 179 4.6E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_20770 0693a0bc08a413121413d5f369e902b0 331 Gene3D G3DSA:3.40.50.2300 70 319 3.8E-67 T 12-10-2018 AFR_20770 0693a0bc08a413121413d5f369e902b0 331 SUPERFAMILY SSF53822 67 328 3.34E-57 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_20770 0693a0bc08a413121413d5f369e902b0 331 SUPERFAMILY SSF47413 4 61 7.11E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_20770 0693a0bc08a413121413d5f369e902b0 331 Gene3D G3DSA:3.40.50.2300 160 324 3.8E-67 T 12-10-2018 AFR_20770 0693a0bc08a413121413d5f369e902b0 331 SMART SM00354 4 73 1.5E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_20770 0693a0bc08a413121413d5f369e902b0 331 Gene3D G3DSA:1.10.260.40 1 61 1.1E-17 T 12-10-2018 AFR_20770 0693a0bc08a413121413d5f369e902b0 331 Pfam PF13377 Periplasmic binding protein-like domain 169 327 3.2E-33 T 12-10-2018 AFR_20770 0693a0bc08a413121413d5f369e902b0 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 49 4.3E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_32610 44143260d0d49e7e9447cb0a5dfeb2cf 144 Pfam PF09656 Putative transmembrane protein (PGPGW) 38 89 3.2E-21 T 12-10-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane AFR_32610 44143260d0d49e7e9447cb0a5dfeb2cf 144 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 35 128 5.2E-23 T 12-10-2018 IPR013434 Conserved hypothetical protein CHP02611 AFR_02065 6f4c55e07d86a64ac914a1f47712f7be 301 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 16 262 2.7E-76 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain AFR_02065 6f4c55e07d86a64ac914a1f47712f7be 301 Gene3D G3DSA:3.90.920.30 22 300 3.1E-93 T 12-10-2018 AFR_25905 b43fa3555643c75a77e04e94f196a41b 239 Gene3D G3DSA:3.40.50.1820 5 234 2.5E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_25905 b43fa3555643c75a77e04e94f196a41b 239 SUPERFAMILY SSF53474 8 229 1.68E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_25905 b43fa3555643c75a77e04e94f196a41b 239 Pfam PF12697 Alpha/beta hydrolase family 8 225 8.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_22875 fb25252b63c6fcb7a624649e45fa7253 280 Gene3D G3DSA:3.40.1090.10 3 100 4.1E-20 T 12-10-2018 AFR_22875 fb25252b63c6fcb7a624649e45fa7253 280 Gene3D G3DSA:3.40.1090.10 101 220 8.0E-16 T 12-10-2018 AFR_22875 fb25252b63c6fcb7a624649e45fa7253 280 SUPERFAMILY SSF52151 10 255 2.12E-50 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_22875 fb25252b63c6fcb7a624649e45fa7253 280 Pfam PF01734 Patatin-like phospholipase 15 172 1.2E-18 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 Gene3D G3DSA:1.10.10.10 7 76 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 Pfam PF07702 UTRA domain 103 236 1.1E-22 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 SMART SM00345 15 74 1.4E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 9.9E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 SUPERFAMILY SSF64288 62 246 4.4E-28 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 SMART SM00866 98 240 1.6E-16 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 SUPERFAMILY SSF46785 12 78 2.16E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26615 b203ca51cb5e240845338a6751fc5f66 263 Gene3D G3DSA:3.40.1410.10 77 242 1.5E-27 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 Gene3D G3DSA:2.40.50.940 223 382 2.0E-28 T 12-10-2018 AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 SUPERFAMILY SSF52540 4 243 8.12E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 SMART SM00382 29 220 6.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 Gene3D G3DSA:2.40.50.140 287 373 2.0E-28 T 12-10-2018 AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 Pfam PF00005 ABC transporter 21 162 1.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 Gene3D G3DSA:3.40.50.300 4 222 6.6E-66 T 12-10-2018 AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 SUPERFAMILY SSF50331 237 389 1.7E-20 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_11410 b1c6574b8652bb279bb934b93d6f6825 402 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_33785 3845724d943f3b42aa934f446e9b0147 441 SUPERFAMILY SSF51905 33 437 3.56E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_33785 3845724d943f3b42aa934f446e9b0147 441 Pfam PF01593 Flavin containing amine oxidoreductase 40 305 4.7E-19 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_33785 3845724d943f3b42aa934f446e9b0147 441 Gene3D G3DSA:3.90.660.10 112 375 8.7E-25 T 12-10-2018 AFR_33785 3845724d943f3b42aa934f446e9b0147 441 Gene3D G3DSA:3.50.50.60 33 308 8.7E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18100 fee841686f1b5695a639f573c5567d80 280 SUPERFAMILY SSF51430 9 275 4.58E-70 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_18100 fee841686f1b5695a639f573c5567d80 280 Pfam PF00248 Aldo/keto reductase family 15 273 1.6E-55 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_18100 fee841686f1b5695a639f573c5567d80 280 Gene3D G3DSA:3.20.20.100 8 278 3.3E-75 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_00940 033dadb811f42480878b6642025c2fa4 461 SUPERFAMILY SSF55103 223 459 1.32E-55 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFR_00940 033dadb811f42480878b6642025c2fa4 461 Gene3D G3DSA:3.30.70.2740 336 418 1.2E-13 T 12-10-2018 AFR_00940 033dadb811f42480878b6642025c2fa4 461 Pfam PF01565 FAD binding domain 39 167 4.4E-42 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_00940 033dadb811f42480878b6642025c2fa4 461 Gene3D G3DSA:3.30.465.40 13 233 1.3E-72 T 12-10-2018 AFR_00940 033dadb811f42480878b6642025c2fa4 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 223 458 3.3E-57 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFR_00940 033dadb811f42480878b6642025c2fa4 461 Gene3D G3DSA:1.10.45.10 419 459 4.5E-13 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFR_00940 033dadb811f42480878b6642025c2fa4 461 SUPERFAMILY SSF56176 5 216 1.5E-64 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_06660 12b902e352eb9b9e1a2c460106ae4bdf 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFR_06660 12b902e352eb9b9e1a2c460106ae4bdf 478 Pfam PF00171 Aldehyde dehydrogenase family 17 473 1.8E-157 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_06660 12b902e352eb9b9e1a2c460106ae4bdf 478 Gene3D G3DSA:3.40.605.10 27 467 5.7E-163 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_06660 12b902e352eb9b9e1a2c460106ae4bdf 478 SUPERFAMILY SSF53720 7 474 1.13E-153 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_06660 12b902e352eb9b9e1a2c460106ae4bdf 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFR_06660 12b902e352eb9b9e1a2c460106ae4bdf 478 Gene3D G3DSA:3.40.309.10 254 442 5.7E-163 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_31390 447dfd06ed1c30f93cc510f1ce1dab62 422 Pfam PF00999 Sodium/hydrogen exchanger family 11 404 1.6E-38 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_35610 36f34df30dcd1d0786ca71f566a469e6 285 SUPERFAMILY SSF53850 5 263 2.67E-55 T 12-10-2018 AFR_35610 36f34df30dcd1d0786ca71f566a469e6 285 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 47 260 8.7E-49 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_35610 36f34df30dcd1d0786ca71f566a469e6 285 SMART SM00062 46 269 2.6E-61 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_35610 36f34df30dcd1d0786ca71f566a469e6 285 Gene3D G3DSA:3.40.190.10 132 231 1.9E-66 T 12-10-2018 AFR_35610 36f34df30dcd1d0786ca71f566a469e6 285 Gene3D G3DSA:3.40.190.10 47 263 1.9E-66 T 12-10-2018 AFR_25975 4e413ca0f02ee56db21951c5d29dbf7d 350 Pfam PF04055 Radical SAM superfamily 115 272 8.1E-10 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_25975 4e413ca0f02ee56db21951c5d29dbf7d 350 TIGRFAM TIGR04043 rSAM_MSMEG_0568: radical SAM protein, MSMEG_0568 family 8 348 3.3E-148 T 12-10-2018 IPR016779 Radical SAM enzyme, MSMEG0568 AFR_25975 4e413ca0f02ee56db21951c5d29dbf7d 350 Gene3D G3DSA:3.20.20.70 99 325 7.6E-9 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_25975 4e413ca0f02ee56db21951c5d29dbf7d 350 SMART SM00729 98 320 8.8E-6 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_25975 4e413ca0f02ee56db21951c5d29dbf7d 350 SUPERFAMILY SSF102114 93 339 4.97E-23 T 12-10-2018 AFR_26845 1abebc379febc0489d7005ab124092a1 108 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 8 91 4.9E-24 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane AFR_26845 1abebc379febc0489d7005ab124092a1 108 Pfam PF12823 Domain of unknown function (DUF3817) 7 92 5.0E-22 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 SUPERFAMILY SSF54292 2 85 4.59E-19 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Gene3D G3DSA:3.30.365.10 607 745 1.3E-97 T 12-10-2018 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Gene3D G3DSA:3.30.365.10 280 514 3.7E-121 T 12-10-2018 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Pfam PF01799 [2Fe-2S] binding domain 70 138 5.5E-27 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Gene3D G3DSA:3.30.365.10 525 885 1.3E-97 T 12-10-2018 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Gene3D G3DSA:1.10.150.120 72 166 2.1E-26 T 12-10-2018 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 SMART SM01008 167 279 1.5E-47 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 167 278 2.5E-28 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Gene3D G3DSA:3.30.365.10 167 438 3.7E-121 T 12-10-2018 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 SUPERFAMILY SSF47741 81 143 1.83E-25 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Gene3D G3DSA:3.10.20.30 1 71 8.1E-25 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 SUPERFAMILY SSF56003 283 891 2.36E-175 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 314 830 2.3E-151 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 SUPERFAMILY SSF54665 148 299 9.03E-41 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily AFR_22785 e24380a0ad6e0000704ed07486650a4c 892 Gene3D G3DSA:3.90.1170.50 182 279 3.7E-121 T 12-10-2018 AFR_15080 6995460579ec56571ce1ac87865b847d 185 Gene3D G3DSA:2.60.120.260 36 183 4.6E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15080 6995460579ec56571ce1ac87865b847d 185 SUPERFAMILY SSF49785 39 181 4.68E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_24280 08082ec1a3439c56da550c82941bf212 426 SUPERFAMILY SSF55486 65 172 3.66E-8 T 12-10-2018 AFR_24280 08082ec1a3439c56da550c82941bf212 426 Pfam PF04228 Putative neutral zinc metallopeptidase 75 215 8.2E-8 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative AFR_14220 b82a0939690cf08195cc9407e388a1b3 341 SMART SM00829 10 335 6.7E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_14220 b82a0939690cf08195cc9407e388a1b3 341 SUPERFAMILY SSF50129 1 137 9.43E-31 T 12-10-2018 IPR011032 GroES-like superfamily AFR_14220 b82a0939690cf08195cc9407e388a1b3 341 Pfam PF00107 Zinc-binding dehydrogenase 164 278 5.1E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_14220 b82a0939690cf08195cc9407e388a1b3 341 Gene3D G3DSA:3.40.50.720 125 301 2.5E-74 T 12-10-2018 AFR_14220 b82a0939690cf08195cc9407e388a1b3 341 Gene3D G3DSA:3.90.180.10 9 333 2.5E-74 T 12-10-2018 AFR_14220 b82a0939690cf08195cc9407e388a1b3 341 SUPERFAMILY SSF51735 118 286 1.93E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14220 b82a0939690cf08195cc9407e388a1b3 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 7.5E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_15650 62551b3c679f42d1f23e0347bc3ac478 253 Gene3D G3DSA:1.20.1290.10 7 253 2.6E-82 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_15650 62551b3c679f42d1f23e0347bc3ac478 253 SUPERFAMILY SSF69118 2 248 2.68E-65 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_15650 62551b3c679f42d1f23e0347bc3ac478 253 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 102 1.0E-6 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_15650 62551b3c679f42d1f23e0347bc3ac478 253 Pfam PF02627 Carboxymuconolactone decarboxylase family 161 232 4.1E-8 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_37150 a6f38dcb6c434897a1e55379b9c0d2ed 304 Pfam PF00085 Thioredoxin 52 154 9.4E-23 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFR_37150 a6f38dcb6c434897a1e55379b9c0d2ed 304 ProSitePatterns PS00194 Thioredoxin family active site. 74 92 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFR_37150 a6f38dcb6c434897a1e55379b9c0d2ed 304 SUPERFAMILY SSF52833 48 159 3.28E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_37150 a6f38dcb6c434897a1e55379b9c0d2ed 304 Gene3D G3DSA:3.40.30.10 49 159 8.3E-28 T 12-10-2018 AFR_37150 a6f38dcb6c434897a1e55379b9c0d2ed 304 Pfam PF14561 Tetratricopeptide repeat 221 304 2.8E-20 T 12-10-2018 AFR_37150 a6f38dcb6c434897a1e55379b9c0d2ed 304 Gene3D G3DSA:1.25.40.10 220 304 5.8E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06400 5931391083faed82a6bfeaa469b55379 669 SUPERFAMILY SSF48452 292 585 2.44E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06400 5931391083faed82a6bfeaa469b55379 669 Pfam PF05704 Capsular polysaccharide synthesis protein 431 659 2.6E-49 T 12-10-2018 IPR008441 Capsular polysaccharide synthesis protein AFR_06400 5931391083faed82a6bfeaa469b55379 669 Gene3D G3DSA:1.25.40.10 237 389 2.7E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06400 5931391083faed82a6bfeaa469b55379 669 SUPERFAMILY SSF53448 439 597 1.87E-12 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_06400 5931391083faed82a6bfeaa469b55379 669 Gene3D G3DSA:2.60.120.260 38 216 6.7E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_12690 bc7c5f95337f08e585ee6ba2d83860b9 456 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 95 338 5.4E-23 T 12-10-2018 IPR010839 Acyclic terpene utilisation AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 SMART SM00382 30 221 2.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 Pfam PF00005 ABC transporter 22 163 6.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 Pfam PF08402 TOBE domain 280 353 5.4E-6 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 Gene3D G3DSA:3.40.50.300 4 223 5.8E-63 T 12-10-2018 AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 SUPERFAMILY SSF50331 238 361 3.4E-21 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 Gene3D G3DSA:2.40.50.940 224 354 1.5E-26 T 12-10-2018 AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 SUPERFAMILY SSF52540 7 244 4.88E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_41085 a64b91a1380e88c98cd765f3afe0792d 361 Gene3D G3DSA:2.40.50.140 286 345 1.5E-26 T 12-10-2018 AFR_09060 848be198167cc85b199f1dfe5c0d7385 161 Pfam PF00583 Acetyltransferase (GNAT) family 48 127 1.6E-12 T 12-10-2018 IPR000182 GNAT domain AFR_09060 848be198167cc85b199f1dfe5c0d7385 161 Gene3D G3DSA:3.40.630.30 43 144 1.6E-21 T 12-10-2018 AFR_09060 848be198167cc85b199f1dfe5c0d7385 161 SUPERFAMILY SSF55729 3 135 3.01E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_09060 848be198167cc85b199f1dfe5c0d7385 161 Gene3D G3DSA:1.10.287.900 1 38 8.1E-6 T 12-10-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117|MetaCyc: PWY-6922 AFR_38785 adf9aa4ab881f386953a8022dbdf50d7 585 Pfam PF00326 Prolyl oligopeptidase family 435 554 9.8E-23 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AFR_38785 adf9aa4ab881f386953a8022dbdf50d7 585 Gene3D G3DSA:3.40.50.1820 390 572 5.3E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_38785 adf9aa4ab881f386953a8022dbdf50d7 585 Gene3D G3DSA:2.140.10.30 89 359 2.2E-23 T 12-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily AFR_38785 adf9aa4ab881f386953a8022dbdf50d7 585 SUPERFAMILY SSF82171 21 355 4.84E-23 T 12-10-2018 AFR_38785 adf9aa4ab881f386953a8022dbdf50d7 585 SUPERFAMILY SSF53474 393 567 2.96E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_39145 45011c4bdab985b5bfb7c6415acd135c 268 Gene3D G3DSA:3.40.50.150 6 261 1.9E-39 T 12-10-2018 AFR_39145 45011c4bdab985b5bfb7c6415acd135c 268 Pfam PF13649 Methyltransferase domain 47 137 1.8E-15 T 12-10-2018 AFR_39145 45011c4bdab985b5bfb7c6415acd135c 268 SUPERFAMILY SSF53335 3 218 3.38E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.0E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 259 3.9E-53 T 12-10-2018 AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 Gene3D G3DSA:3.40.50.720 1 262 3.9E-81 T 12-10-2018 AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 SUPERFAMILY SSF51735 7 260 1.02E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_34635 a68fd3ca36de9e19a6b7575207438ba0 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_34675 ff612e509744176d21ad11cd0026c718 334 SUPERFAMILY SSF53850 44 327 2.26E-55 T 12-10-2018 AFR_34675 ff612e509744176d21ad11cd0026c718 334 Pfam PF16868 NMT1-like family 48 324 3.6E-65 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFR_34675 ff612e509744176d21ad11cd0026c718 334 Gene3D G3DSA:3.40.190.10 48 324 3.1E-78 T 12-10-2018 AFR_34675 ff612e509744176d21ad11cd0026c718 334 Gene3D G3DSA:3.40.190.10 130 268 3.1E-78 T 12-10-2018 AFR_34675 ff612e509744176d21ad11cd0026c718 334 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 325 5.7E-76 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFR_35460 39ab2c1c24737406333828e8bb0dee8a 404 Gene3D G3DSA:1.20.1250.20 203 387 6.8E-16 T 12-10-2018 AFR_35460 39ab2c1c24737406333828e8bb0dee8a 404 SUPERFAMILY SSF103473 6 398 1.31E-36 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_35460 39ab2c1c24737406333828e8bb0dee8a 404 Pfam PF07690 Major Facilitator Superfamily 20 228 6.7E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_35460 39ab2c1c24737406333828e8bb0dee8a 404 Gene3D G3DSA:1.20.1250.20 15 202 7.2E-14 T 12-10-2018 AFR_22980 9dc3ab22ee21406e5168852ffd0fae61 228 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_22980 9dc3ab22ee21406e5168852ffd0fae61 228 Gene3D G3DSA:1.10.357.10 4 212 2.4E-38 T 12-10-2018 AFR_22980 9dc3ab22ee21406e5168852ffd0fae61 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.3E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22980 9dc3ab22ee21406e5168852ffd0fae61 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22980 9dc3ab22ee21406e5168852ffd0fae61 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22980 9dc3ab22ee21406e5168852ffd0fae61 228 SUPERFAMILY SSF46689 6 77 6.16E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_09335 f30e4ab0926b659dfc8beb510c9c5b23 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 97 1.3E-14 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD AFR_35230 158e8fece11fcd0037331590b7a8e909 230 SMART SM00862 145 217 1.3E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_35230 158e8fece11fcd0037331590b7a8e909 230 Pfam PF00072 Response regulator receiver domain 3 113 2.4E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35230 158e8fece11fcd0037331590b7a8e909 230 Gene3D G3DSA:1.10.10.10 123 221 3.9E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35230 158e8fece11fcd0037331590b7a8e909 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.4E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_35230 158e8fece11fcd0037331590b7a8e909 230 Gene3D G3DSA:3.40.50.2300 1 121 6.8E-34 T 12-10-2018 AFR_35230 158e8fece11fcd0037331590b7a8e909 230 SMART SM00448 1 112 3.7E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35230 158e8fece11fcd0037331590b7a8e909 230 SUPERFAMILY SSF52172 2 172 2.87E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_11820 2fe4fcfbef3bcb9b7d56483c3cfe9df6 170 SUPERFAMILY SSF109854 45 160 1.13E-9 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_11820 2fe4fcfbef3bcb9b7d56483c3cfe9df6 170 Gene3D G3DSA:1.20.120.450 41 167 1.4E-10 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_28710 89b164fa06bbce52d80ad58820375287 351 SUPERFAMILY SSF56300 126 348 8.62E-38 T 12-10-2018 AFR_28710 89b164fa06bbce52d80ad58820375287 351 Pfam PF00149 Calcineurin-like phosphoesterase 130 291 3.3E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_28710 89b164fa06bbce52d80ad58820375287 351 Gene3D G3DSA:3.60.21.10 129 314 7.5E-21 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_14775 6c462fc06dc0389c1f48caece0ff1fc7 431 SUPERFAMILY SSF53850 27 430 3.16E-70 T 12-10-2018 AFR_14775 6c462fc06dc0389c1f48caece0ff1fc7 431 Pfam PF01547 Bacterial extracellular solute-binding protein 50 348 1.6E-36 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_14775 6c462fc06dc0389c1f48caece0ff1fc7 431 Gene3D G3DSA:3.40.190.10 153 423 2.1E-107 T 12-10-2018 AFR_14775 6c462fc06dc0389c1f48caece0ff1fc7 431 Gene3D G3DSA:3.40.190.10 56 389 2.1E-107 T 12-10-2018 AFR_30425 2ef843e08b4fa41ef04fc15228ae6d69 155 SUPERFAMILY SSF109854 5 150 1.04E-34 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_30425 2ef843e08b4fa41ef04fc15228ae6d69 155 Gene3D G3DSA:1.20.120.450 2 154 2.1E-29 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_30425 2ef843e08b4fa41ef04fc15228ae6d69 155 Pfam PF04978 Protein of unknown function (DUF664) 17 151 3.4E-29 T 12-10-2018 IPR007061 Protein of unknown function DUF664 AFR_32690 a4a7a07bb401a669da5f2890cce6f84c 312 Pfam PF13354 Beta-lactamase enzyme family 143 234 1.9E-9 T 12-10-2018 AFR_32690 a4a7a07bb401a669da5f2890cce6f84c 312 SUPERFAMILY SSF56601 84 310 6.87E-26 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_32690 a4a7a07bb401a669da5f2890cce6f84c 312 Gene3D G3DSA:3.40.710.10 76 311 8.6E-33 T 12-10-2018 AFR_38930 32214c52be0a0d9d07f744f551686461 327 Gene3D G3DSA:3.30.565.10 195 321 4.9E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38930 32214c52be0a0d9d07f744f551686461 327 Pfam PF13581 Histidine kinase-like ATPase domain 225 285 8.7E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_38930 32214c52be0a0d9d07f744f551686461 327 SUPERFAMILY SSF55874 198 319 8.77E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07660 3356bc9302ab3fa55fe8de88488c6dea 650 SMART SM00729 264 487 3.8E-26 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_07660 3356bc9302ab3fa55fe8de88488c6dea 650 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 12 618 2.7E-208 T 12-10-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM AFR_07660 3356bc9302ab3fa55fe8de88488c6dea 650 SUPERFAMILY SSF102114 230 635 1.24E-46 T 12-10-2018 AFR_07660 3356bc9302ab3fa55fe8de88488c6dea 650 Gene3D G3DSA:3.80.30.20 263 493 4.6E-17 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFR_07660 3356bc9302ab3fa55fe8de88488c6dea 650 Pfam PF04055 Radical SAM superfamily 268 429 1.3E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_23415 e9bd39d3562a0eee39944b2a48f9d1b2 345 SUPERFAMILY SSF51735 140 294 2.72E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23415 e9bd39d3562a0eee39944b2a48f9d1b2 345 SUPERFAMILY SSF50129 7 175 3.77E-41 T 12-10-2018 IPR011032 GroES-like superfamily AFR_23415 e9bd39d3562a0eee39944b2a48f9d1b2 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 135 2.5E-20 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_23415 e9bd39d3562a0eee39944b2a48f9d1b2 345 Gene3D G3DSA:3.90.180.10 14 314 3.4E-82 T 12-10-2018 AFR_23415 e9bd39d3562a0eee39944b2a48f9d1b2 345 Gene3D G3DSA:3.40.50.720 153 275 3.4E-82 T 12-10-2018 AFR_23415 e9bd39d3562a0eee39944b2a48f9d1b2 345 Pfam PF00107 Zinc-binding dehydrogenase 176 289 2.8E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Pfam PF00703 Glycosyl hydrolases family 2 232 301 3.7E-6 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Gene3D G3DSA:3.20.20.80 313 585 4.3E-45 T 12-10-2018 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 SUPERFAMILY SSF49785 42 210 1.7E-48 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 SUPERFAMILY SSF110221 592 740 4.45E-47 T 12-10-2018 IPR036195 Alpha-L-arabinofuranosidase B, arabinose-binding domain superfamily GO:0046373|GO:0046556 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 SUPERFAMILY SSF110221 742 899 1.96E-51 T 12-10-2018 IPR036195 Alpha-L-arabinofuranosidase B, arabinose-binding domain superfamily GO:0046373|GO:0046556 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 SUPERFAMILY SSF49303 214 302 1.15E-11 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 SUPERFAMILY SSF51445 298 581 1.09E-55 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 603 736 4.5E-47 T 12-10-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 756 897 4.1E-52 T 12-10-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 86 207 7.3E-19 T 12-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Gene3D G3DSA:2.60.40.10 213 302 4.7E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Gene3D G3DSA:2.80.10.50 742 902 6.8E-58 T 12-10-2018 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Gene3D G3DSA:2.80.10.50 589 741 2.5E-52 T 12-10-2018 AFR_02450 a4297322589c0ae8b52b7968dfa59a9b 903 Gene3D G3DSA:2.60.120.260 47 210 3.2E-40 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_09210 02a99b4f9906e482908ecacc76b02c4e 310 Gene3D G3DSA:3.40.50.1820 26 308 1.3E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_09210 02a99b4f9906e482908ecacc76b02c4e 310 SUPERFAMILY SSF53474 24 271 1.51E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 Pfam PF01965 DJ-1/PfpI family 62 168 1.5E-15 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 SUPERFAMILY SSF46689 260 309 7.62E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 SMART SM00342 223 306 6.4E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 SUPERFAMILY SSF46689 208 256 3.4E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 260 302 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 SUPERFAMILY SSF52317 1 189 2.55E-44 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 Pfam PF12833 Helix-turn-helix domain 229 307 3.3E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 Gene3D G3DSA:1.10.10.60 208 311 6.7E-26 T 12-10-2018 AFR_26295 78b6c1db7fe80756d07a0479c48cea4d 311 Gene3D G3DSA:3.40.50.880 2 204 1.5E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_25330 dd3b7d71717fdfdc650cc735d4e2f96a 84 Pfam PF04024 PspC domain 13 68 1.1E-16 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal AFR_07880 de7f981fb039c244fc84efe4ec4d1f54 582 SUPERFAMILY SSF52540 336 571 1.33E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07880 de7f981fb039c244fc84efe4ec4d1f54 582 Gene3D G3DSA:3.40.50.300 335 581 2.4E-64 T 12-10-2018 AFR_07880 de7f981fb039c244fc84efe4ec4d1f54 582 SMART SM00382 366 548 4.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_07880 de7f981fb039c244fc84efe4ec4d1f54 582 Gene3D G3DSA:1.20.1560.10 6 330 4.4E-60 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_07880 de7f981fb039c244fc84efe4ec4d1f54 582 SUPERFAMILY SSF90123 16 328 1.83E-60 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_07880 de7f981fb039c244fc84efe4ec4d1f54 582 Pfam PF00664 ABC transporter transmembrane region 32 299 4.4E-34 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_07880 de7f981fb039c244fc84efe4ec4d1f54 582 Pfam PF00005 ABC transporter 357 502 5.8E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01800 5491121ccee79000f17671af27d267b6 782 PIRSF PIRSF007519 132 779 5.3E-167 T 12-10-2018 IPR012300 Peptidase M6, InhA AFR_01800 5491121ccee79000f17671af27d267b6 782 PIRSF PIRSF007519 19 135 0.14 T 12-10-2018 IPR012300 Peptidase M6, InhA AFR_01800 5491121ccee79000f17671af27d267b6 782 SUPERFAMILY SSF55486 220 409 9.87E-13 T 12-10-2018 AFR_01800 5491121ccee79000f17671af27d267b6 782 Pfam PF05547 Immune inhibitor A peptidase M6 91 773 1.3E-182 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_01800 5491121ccee79000f17671af27d267b6 782 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 154 443 6.3E-72 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_28965 88b8f12e0e93c570fd071347f99535a9 124 SUPERFAMILY SSF52172 4 117 1.05E-29 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28965 88b8f12e0e93c570fd071347f99535a9 124 Gene3D G3DSA:3.40.50.2300 3 124 3.4E-28 T 12-10-2018 AFR_28965 88b8f12e0e93c570fd071347f99535a9 124 Pfam PF00072 Response regulator receiver domain 5 105 7.8E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28965 88b8f12e0e93c570fd071347f99535a9 124 SMART SM00448 3 116 3.3E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_36070 395346d689d88216062f18c500d988cc 279 Gene3D G3DSA:3.40.50.720 1 274 1.4E-58 T 12-10-2018 AFR_36070 395346d689d88216062f18c500d988cc 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.3E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36070 395346d689d88216062f18c500d988cc 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 8.3E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36070 395346d689d88216062f18c500d988cc 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 8.3E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36070 395346d689d88216062f18c500d988cc 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 8 8.3E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36070 395346d689d88216062f18c500d988cc 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 8.3E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_36070 395346d689d88216062f18c500d988cc 279 SUPERFAMILY SSF51735 1 243 1.79E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36070 395346d689d88216062f18c500d988cc 279 Pfam PF00106 short chain dehydrogenase 1 198 5.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31985 ae479162fd671b8f53f37f23a988754a 131 Gene3D G3DSA:1.10.10.10 2 131 2.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31985 ae479162fd671b8f53f37f23a988754a 131 SUPERFAMILY SSF46785 18 130 8.65E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31985 ae479162fd671b8f53f37f23a988754a 131 SMART SM00347 21 120 9.1E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31985 ae479162fd671b8f53f37f23a988754a 131 Pfam PF12802 MarR family 26 79 2.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_01215 428f9f958cb13eef32ea60b0c6b1098c 145 Gene3D G3DSA:3.30.750.24 10 128 1.2E-26 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01215 428f9f958cb13eef32ea60b0c6b1098c 145 Pfam PF01740 STAS domain 19 105 6.3E-6 T 12-10-2018 IPR002645 STAS domain AFR_01215 428f9f958cb13eef32ea60b0c6b1098c 145 SUPERFAMILY SSF52091 12 121 1.28E-14 T 12-10-2018 IPR036513 STAS domain superfamily AFR_33915 995847828e15ab59059bb262e0bbf80e 222 Gene3D G3DSA:2.60.120.260 70 222 3.1E-41 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33915 995847828e15ab59059bb262e0bbf80e 222 SMART SM00606 86 222 3.8E-41 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 AFR_33915 995847828e15ab59059bb262e0bbf80e 222 SUPERFAMILY SSF49785 86 221 3.57E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_33915 995847828e15ab59059bb262e0bbf80e 222 Pfam PF03422 Carbohydrate binding module (family 6) 94 221 9.8E-36 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_40200 f85ef9a96b489c2e5d977787e0e6bfad 501 Pfam PF00501 AMP-binding enzyme 10 410 3.9E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_40200 f85ef9a96b489c2e5d977787e0e6bfad 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_40200 f85ef9a96b489c2e5d977787e0e6bfad 501 Gene3D G3DSA:3.30.300.310 406 501 8.2E-28 T 12-10-2018 AFR_40200 f85ef9a96b489c2e5d977787e0e6bfad 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 494 2.1E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_40200 f85ef9a96b489c2e5d977787e0e6bfad 501 SUPERFAMILY SSF56801 4 501 1.83E-126 T 12-10-2018 AFR_40200 f85ef9a96b489c2e5d977787e0e6bfad 501 Gene3D G3DSA:3.40.50.12780 2 404 5.9E-94 T 12-10-2018 AFR_42950 5d37a6232a2d3a416ee5c704959e6a94 430 Gene3D G3DSA:3.90.1150.10 25 397 4.6E-129 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_42950 5d37a6232a2d3a416ee5c704959e6a94 430 Gene3D G3DSA:3.40.640.10 72 292 4.6E-129 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_42950 5d37a6232a2d3a416ee5c704959e6a94 430 Pfam PF00155 Aminotransferase class I and II 66 394 4.4E-37 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_42950 5d37a6232a2d3a416ee5c704959e6a94 430 SUPERFAMILY SSF53383 10 400 1.25E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_27195 accd63a8a8a1ba8f932e377746dc82bc 283 Gene3D G3DSA:3.40.50.720 142 246 2.3E-16 T 12-10-2018 AFR_27195 accd63a8a8a1ba8f932e377746dc82bc 283 Pfam PF13478 XdhC Rossmann domain 119 226 1.5E-16 T 12-10-2018 IPR027051 XdhC Rossmann domain AFR_27195 accd63a8a8a1ba8f932e377746dc82bc 283 Pfam PF02625 XdhC and CoxI family 13 77 1.1E-14 T 12-10-2018 IPR003777 XdhC- CoxI AFR_04855 aa2970900a7572e0ba4b17b7998588f7 236 SUPERFAMILY SSF53067 20 121 7.12E-19 T 12-10-2018 AFR_04855 aa2970900a7572e0ba4b17b7998588f7 236 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 21 221 2.8E-48 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 AFR_04855 aa2970900a7572e0ba4b17b7998588f7 236 Gene3D G3DSA:3.30.420.40 21 221 4.9E-40 T 12-10-2018 AFR_04855 aa2970900a7572e0ba4b17b7998588f7 236 Pfam PF00814 Glycoprotease family 55 186 2.1E-22 T 12-10-2018 IPR000905 Gcp-like domain AFR_04855 aa2970900a7572e0ba4b17b7998588f7 236 Gene3D G3DSA:3.30.420.40 117 192 4.9E-40 T 12-10-2018 AFR_04855 aa2970900a7572e0ba4b17b7998588f7 236 SUPERFAMILY SSF53067 128 219 7.77E-11 T 12-10-2018 AFR_25385 b5259673c872b7869c17b1b9d70b9fe0 314 Gene3D G3DSA:2.70.50.50 31 211 3.7E-52 T 12-10-2018 AFR_25385 b5259673c872b7869c17b1b9d70b9fe0 314 SUPERFAMILY SSF81296 31 210 7.98E-40 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_25385 b5259673c872b7869c17b1b9d70b9fe0 314 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 207 5.6E-37 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 SMART SM00331 390 603 4.8E-34 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 Gene3D G3DSA:3.30.450.20 226 293 9.1E-8 T 12-10-2018 AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 SUPERFAMILY SSF55785 289 342 9.21E-5 T 12-10-2018 IPR035965 PAS domain superfamily AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 Gene3D G3DSA:3.60.40.10 352 603 1.3E-59 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 SMART SM01012 11 72 1.8E-4 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 Pfam PF03861 ANTAR domain 29 72 1.4E-7 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 Gene3D G3DSA:2.10.70.100 300 343 3.9E-7 T 12-10-2018 AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 SUPERFAMILY SSF81606 400 601 1.44E-11 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_24785 c280408a6c1c802c4b57485cec2aa49a 618 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 417 602 2.6E-46 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_15870 2d26fad1c2cc6c32ebadb30fa39dce5f 312 SUPERFAMILY SSF53850 20 230 3.06E-9 T 12-10-2018 AFR_15870 2d26fad1c2cc6c32ebadb30fa39dce5f 312 PIRSF PIRSF017082 3 311 9.5E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 AFR_15870 2d26fad1c2cc6c32ebadb30fa39dce5f 312 Gene3D G3DSA:3.40.190.10 112 236 3.0E-60 T 12-10-2018 AFR_15870 2d26fad1c2cc6c32ebadb30fa39dce5f 312 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 36 306 1.7E-23 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 AFR_15870 2d26fad1c2cc6c32ebadb30fa39dce5f 312 Gene3D G3DSA:3.40.190.150 16 300 3.0E-60 T 12-10-2018 AFR_27410 cecc41af982d3854af930607823bd44d 978 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 287 4.5E-117 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 SUPERFAMILY SSF55681 3 280 3.73E-107 T 12-10-2018 AFR_27410 cecc41af982d3854af930607823bd44d 978 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 308 976 19.81 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 SUPERFAMILY SSF109604 655 780 2.67E-7 T 12-10-2018 AFR_27410 cecc41af982d3854af930607823bd44d 978 Gene3D G3DSA:1.20.58.180 206 286 4.5E-24 T 12-10-2018 AFR_27410 cecc41af982d3854af930607823bd44d 978 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 282 49.514 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 Gene3D G3DSA:3.30.930.10 1 205 8.7E-101 T 12-10-2018 AFR_27410 cecc41af982d3854af930607823bd44d 978 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 280 1.1E-123 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 309 968 8.7E-149 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 311 845 5.3E-162 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 242 258 1.1E-53 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 1.1E-53 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 1.1E-53 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 1.1E-53 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 1.1E-53 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_27410 cecc41af982d3854af930607823bd44d 978 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 1.1E-53 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFR_35970 9d06ccccefacd4f4bd102bae13ddad98 341 Pfam PF01170 Putative RNA methylase family UPF0020 139 283 2.5E-6 T 12-10-2018 IPR000241 Putative RNA methylase domain AFR_35970 9d06ccccefacd4f4bd102bae13ddad98 341 SUPERFAMILY SSF53335 128 293 2.43E-12 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_35070 479f3a54f03660b6d10b2a8d78bdbaf5 158 Gene3D G3DSA:3.40.630.30 2 157 2.0E-37 T 12-10-2018 AFR_35070 479f3a54f03660b6d10b2a8d78bdbaf5 158 SUPERFAMILY SSF55729 3 152 2.74E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35070 479f3a54f03660b6d10b2a8d78bdbaf5 158 Pfam PF00583 Acetyltransferase (GNAT) family 44 147 3.1E-16 T 12-10-2018 IPR000182 GNAT domain AFR_27040 92587e49c0e9309b272e772496c864e4 316 SMART SM00014 104 211 7.1E-5 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_27040 92587e49c0e9309b272e772496c864e4 316 Pfam PF01569 PAP2 superfamily 138 216 3.5E-11 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_27040 92587e49c0e9309b272e772496c864e4 316 Gene3D G3DSA:1.20.144.10 134 232 2.3E-12 T 12-10-2018 AFR_27040 92587e49c0e9309b272e772496c864e4 316 SUPERFAMILY SSF48317 55 217 5.89E-15 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_37025 2397c356cd0038175802a12619c1a31b 319 SUPERFAMILY SSF52402 4 187 1.53E-36 T 12-10-2018 AFR_37025 2397c356cd0038175802a12619c1a31b 319 Gene3D G3DSA:3.40.50.620 3 187 3.1E-37 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_37025 2397c356cd0038175802a12619c1a31b 319 PIRSF PIRSF000089 1 319 1.3E-99 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AFR_37025 2397c356cd0038175802a12619c1a31b 319 Pfam PF01012 Electron transfer flavoprotein domain 4 169 1.3E-31 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFR_37025 2397c356cd0038175802a12619c1a31b 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 AFR_37025 2397c356cd0038175802a12619c1a31b 319 SUPERFAMILY SSF52467 195 311 8.18E-47 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFR_37025 2397c356cd0038175802a12619c1a31b 319 SMART SM00893 4 187 1.9E-25 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFR_37025 2397c356cd0038175802a12619c1a31b 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 3.6E-36 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AFR_37025 2397c356cd0038175802a12619c1a31b 319 Gene3D G3DSA:3.40.50.1220 190 319 1.9E-55 T 12-10-2018 AFR_35525 71781686a5514b260c6228688e4a71f0 260 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 36 83 1.0E-13 T 12-10-2018 IPR027805 Transposase, Helix-turn-helix domain AFR_35525 71781686a5514b260c6228688e4a71f0 260 Pfam PF13359 DDE superfamily endonuclease 102 251 6.9E-32 T 12-10-2018 IPR027806 Harbinger transposase-derived nuclease domain AFR_29765 68e19145ee5f804e6fd851bc170a3b58 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29765 68e19145ee5f804e6fd851bc170a3b58 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29765 68e19145ee5f804e6fd851bc170a3b58 204 Gene3D G3DSA:1.10.357.10 4 203 2.9E-37 T 12-10-2018 AFR_29765 68e19145ee5f804e6fd851bc170a3b58 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.6E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29765 68e19145ee5f804e6fd851bc170a3b58 204 SUPERFAMILY SSF46689 10 75 2.24E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29765 68e19145ee5f804e6fd851bc170a3b58 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_13960 32a03adb0c77052354b05f6b7e43312d 359 SUPERFAMILY SSF51735 156 324 4.36E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13960 32a03adb0c77052354b05f6b7e43312d 359 Gene3D G3DSA:3.90.180.10 5 346 1.4E-48 T 12-10-2018 AFR_13960 32a03adb0c77052354b05f6b7e43312d 359 SUPERFAMILY SSF50129 1 183 1.19E-26 T 12-10-2018 IPR011032 GroES-like superfamily AFR_13960 32a03adb0c77052354b05f6b7e43312d 359 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 138 1.3E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_13960 32a03adb0c77052354b05f6b7e43312d 359 Gene3D G3DSA:3.40.50.720 151 303 1.4E-48 T 12-10-2018 AFR_30295 8a9dadc60cf80a7945150d182eaa860a 65 Gene3D G3DSA:3.30.70.20 1 64 9.9E-12 T 12-10-2018 AFR_30295 8a9dadc60cf80a7945150d182eaa860a 65 SUPERFAMILY SSF54862 3 63 2.92E-9 T 12-10-2018 AFR_30295 8a9dadc60cf80a7945150d182eaa860a 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 61 8.3E-9 T 12-10-2018 AFR_04340 db49307beb8e9cd5eef84e3d187b5e74 398 Pfam PF04542 Sigma-70 region 2 17 74 1.9E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_04340 db49307beb8e9cd5eef84e3d187b5e74 398 SUPERFAMILY SSF88946 5 71 1.61E-9 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_04340 db49307beb8e9cd5eef84e3d187b5e74 398 SUPERFAMILY SSF48452 15 382 5.46E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_04340 db49307beb8e9cd5eef84e3d187b5e74 398 SUPERFAMILY SSF88659 94 153 7.85E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_04340 db49307beb8e9cd5eef84e3d187b5e74 398 Pfam PF13181 Tetratricopeptide repeat 356 380 0.13 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_26665 bd299be249607a8443ed021b13de12e8 152 Pfam PF11695 Domain of unknown function (DUF3291) 6 142 2.9E-57 T 12-10-2018 IPR021708 Domain of unknown function DUF3291 AFR_26665 bd299be249607a8443ed021b13de12e8 152 SUPERFAMILY SSF54909 20 117 3.93E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_36425 7beec2d1dc546e5d0179fda2df16c874 451 ProSitePatterns PS01219 Ammonium transporters signature. 170 195 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFR_36425 7beec2d1dc546e5d0179fda2df16c874 451 TIGRFAM TIGR00836 amt: ammonium transporter 7 416 1.5E-137 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFR_36425 7beec2d1dc546e5d0179fda2df16c874 451 Gene3D G3DSA:1.10.3430.10 1 430 9.9E-136 T 12-10-2018 IPR029020 Ammonium/urea transporter AFR_36425 7beec2d1dc546e5d0179fda2df16c874 451 SUPERFAMILY SSF111352 3 397 5.89E-121 T 12-10-2018 AFR_36425 7beec2d1dc546e5d0179fda2df16c874 451 Pfam PF00909 Ammonium Transporter Family 9 416 3.6E-124 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFR_11045 095efbc159e73a5d2ab01b9bece4042a 255 PIRSF PIRSF000094 2 255 3.7E-83 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFR_11045 095efbc159e73a5d2ab01b9bece4042a 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 1.3E-66 T 12-10-2018 AFR_11045 095efbc159e73a5d2ab01b9bece4042a 255 Gene3D G3DSA:3.40.50.720 2 253 2.6E-46 T 12-10-2018 AFR_11045 095efbc159e73a5d2ab01b9bece4042a 255 SUPERFAMILY SSF51735 7 252 2.05E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_04630 154768ecbfd44a370cb717ec3662b6f1 73 SUPERFAMILY SSF50249 4 72 5.57E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_04630 154768ecbfd44a370cb717ec3662b6f1 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 2.7E-29 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AFR_04630 154768ecbfd44a370cb717ec3662b6f1 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 3.2E-37 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFR_04630 154768ecbfd44a370cb717ec3662b6f1 73 Gene3D G3DSA:2.40.50.140 1 73 5.8E-38 T 12-10-2018 AFR_04630 154768ecbfd44a370cb717ec3662b6f1 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.168 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFR_00910 606cae349c87c7d0552b81b7182400b1 330 SUPERFAMILY SSF56601 1 316 1.64E-62 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_00910 606cae349c87c7d0552b81b7182400b1 330 Pfam PF00144 Beta-lactamase 1 320 2.6E-57 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_00910 606cae349c87c7d0552b81b7182400b1 330 Gene3D G3DSA:3.40.710.30 1 327 2.2E-88 T 12-10-2018 AFR_28200 20b6319251880cc2b020a9eb09ca579b 369 Pfam PF01882 Protein of unknown function DUF58 189 266 1.1E-19 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_10995 894c7620209603b97fd0dc6560ea4399 173 Pfam PF03703 Bacterial PH domain 85 162 1.1E-15 T 12-10-2018 IPR005182 Domain of unknown function DUF304 AFR_12735 a0be5fe4ecb6b5315e6553b6bee2deee 409 Pfam PF07282 Putative transposase DNA-binding domain 297 364 1.4E-18 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_12735 a0be5fe4ecb6b5315e6553b6bee2deee 409 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 253 324 3.1E-6 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_12735 a0be5fe4ecb6b5315e6553b6bee2deee 409 Pfam PF12323 Helix-turn-helix domain 2 46 4.0E-16 T 12-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFR_12735 a0be5fe4ecb6b5315e6553b6bee2deee 409 Pfam PF01385 Probable transposase 176 282 4.1E-23 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 SUPERFAMILY SSF50129 12 98 7.69E-17 T 12-10-2018 IPR011032 GroES-like superfamily AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 Gene3D G3DSA:2.30.33.40 11 100 3.4E-12 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 SMART SM00883 12 99 8.6E-23 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 Pfam PF00166 Chaperonin 10 Kd subunit 12 98 2.8E-16 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 PRINTS PR00297 10kDa chaperonin signature 37 58 3.0E-10 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 PRINTS PR00297 10kDa chaperonin signature 13 28 3.0E-10 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 PRINTS PR00297 10kDa chaperonin signature 65 77 3.0E-10 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_40830 c746c6c3bf182e88f0c020f92559c6cb 112 PRINTS PR00297 10kDa chaperonin signature 86 99 3.0E-10 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFR_06630 718e2e011ce533f964dd6d6d4050ff43 262 Pfam PF01734 Patatin-like phospholipase 6 182 4.1E-15 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFR_06630 718e2e011ce533f964dd6d6d4050ff43 262 SUPERFAMILY SSF52151 2 213 4.97E-27 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_06630 718e2e011ce533f964dd6d6d4050ff43 262 Gene3D G3DSA:3.40.1090.10 105 205 2.3E-15 T 12-10-2018 AFR_39210 d5677e555d0197ccc85050e9e75f571a 405 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 17 405 3.2E-122 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFR_39210 d5677e555d0197ccc85050e9e75f571a 405 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 9 405 24.212 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFR_39210 d5677e555d0197ccc85050e9e75f571a 405 Pfam PF13742 OB-fold nucleic acid binding domain 17 109 7.2E-13 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 AFR_39210 d5677e555d0197ccc85050e9e75f571a 405 Pfam PF02601 Exonuclease VII, large subunit 133 351 3.5E-66 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 AFR_39210 d5677e555d0197ccc85050e9e75f571a 405 Pfam PF02601 Exonuclease VII, large subunit 340 402 2.9E-12 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 Pfam PF00230 Major intrinsic protein 2 200 1.3E-29 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 SUPERFAMILY SSF81338 2 204 3.66E-43 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 Gene3D G3DSA:1.20.1080.10 1 213 2.8E-44 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 PRINTS PR00783 Major intrinsic protein family signature 33 57 7.7E-33 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 PRINTS PR00783 Major intrinsic protein family signature 114 132 7.7E-33 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 PRINTS PR00783 Major intrinsic protein family signature 184 204 7.7E-33 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 PRINTS PR00783 Major intrinsic protein family signature 2 21 7.7E-33 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 PRINTS PR00783 Major intrinsic protein family signature 70 89 7.7E-33 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 PRINTS PR00783 Major intrinsic protein family signature 146 168 7.7E-33 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_12385 5e985b76b2841ee0287140ac8c4d4446 239 ProSitePatterns PS00221 MIP family signature. 51 59 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 AFR_35955 2c81302804eeb49907a56a56c0750eac 343 Pfam PF01368 DHH family 31 174 3.3E-9 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFR_35955 2c81302804eeb49907a56a56c0750eac 343 Pfam PF02272 DHHA1 domain 276 321 9.6E-8 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFR_35955 2c81302804eeb49907a56a56c0750eac 343 Gene3D G3DSA:3.90.1640.10 17 214 5.8E-46 T 12-10-2018 AFR_35955 2c81302804eeb49907a56a56c0750eac 343 Gene3D G3DSA:3.10.310.30 215 338 8.4E-30 T 12-10-2018 AFR_35955 2c81302804eeb49907a56a56c0750eac 343 SUPERFAMILY SSF64182 31 324 1.22E-53 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 392 407 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 416 433 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 81 100 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 194 210 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 356 374 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 63 81 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 332 350 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 224 243 2.5E-51 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 SUPERFAMILY SSF56235 1 512 5.98E-118 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_31715 a3e135655e765788c829c56d8a3c1088 521 Pfam PF01019 Gamma-glutamyltranspeptidase 1 509 4.7E-124 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 Gene3D G3DSA:1.10.246.130 210 320 2.0E-23 T 12-10-2018 AFR_31715 a3e135655e765788c829c56d8a3c1088 521 Gene3D G3DSA:3.60.20.40 332 516 4.1E-52 T 12-10-2018 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 Gene3D G3DSA:3.40.50.720 137 341 1.8E-130 T 12-10-2018 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 SMART SM00839 147 356 7.0E-45 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 Gene3D G3DSA:3.40.50.10860 14 348 1.8E-130 T 12-10-2018 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 19 134 4.8E-25 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 77 90 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 PIRSF PIRSF000188 5 358 3.5E-140 T 12-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 291 302 5.7E-21 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 135 157 5.7E-21 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 69 83 5.7E-21 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 179 199 5.7E-21 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 SUPERFAMILY SSF53223 12 147 5.44E-46 T 12-10-2018 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 SUPERFAMILY SSF51735 144 355 4.42E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 144 205 2.2E-5 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_00765 e020add5cd835c7303dbb4482b5aff91 360 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 221 298 2.0E-10 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFR_15445 b7407bba9d975d0f9f20fa33ac42c87c 362 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 33 156 6.2E-8 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 AFR_15445 b7407bba9d975d0f9f20fa33ac42c87c 362 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 201 341 2.5E-7 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 AFR_15445 b7407bba9d975d0f9f20fa33ac42c87c 362 SUPERFAMILY SSF53474 32 299 9.97E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15445 b7407bba9d975d0f9f20fa33ac42c87c 362 Gene3D G3DSA:3.40.50.1820 28 350 5.2E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 SUPERFAMILY SSF55486 32 161 1.39E-20 T 12-10-2018 AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 Gene3D G3DSA:3.40.390.10 32 164 2.1E-36 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 34 161 7.4E-29 T 12-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 97 121 4.5E-22 T 12-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 38 64 4.5E-22 T 12-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 122 146 4.5E-22 T 12-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 149 163 4.5E-22 T 12-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 AFR_06010 5165c5c083374b2303c83354c1fb2c96 176 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 39 157 3.0E-34 T 12-10-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 AFR_32880 50974709dd2377c1204218b071a3b36b 288 SUPERFAMILY SSF53686 4 284 2.88E-62 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_32880 50974709dd2377c1204218b071a3b36b 288 Gene3D G3DSA:3.40.50.1100 43 136 2.5E-80 T 12-10-2018 AFR_32880 50974709dd2377c1204218b071a3b36b 288 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 277 4.3E-46 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_32880 50974709dd2377c1204218b071a3b36b 288 Gene3D G3DSA:3.40.50.1100 9 283 2.5E-80 T 12-10-2018 AFR_32880 50974709dd2377c1204218b071a3b36b 288 PIRSF PIRSF006278 2 288 2.5E-66 T 12-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase AFR_02175 692adcc47520e121f429090fa4ab6ef8 365 SUPERFAMILY SSF69304 79 326 1.57E-10 T 12-10-2018 AFR_02175 692adcc47520e121f429090fa4ab6ef8 365 Gene3D G3DSA:2.120.10.30 88 285 1.2E-9 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_13175 1a5f3d127fc43ac2eef87453aee990ee 130 Gene3D G3DSA:3.10.450.50 3 128 1.1E-38 T 12-10-2018 AFR_13175 1a5f3d127fc43ac2eef87453aee990ee 130 SUPERFAMILY SSF54427 5 128 8.11E-31 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_13175 1a5f3d127fc43ac2eef87453aee990ee 130 Pfam PF07366 SnoaL-like polyketide cyclase 9 128 7.0E-33 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 AFR_37215 f93a8cf4f5728cd2a8054e27165738ca 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 19 133 1.0E-21 T 12-10-2018 AFR_37215 f93a8cf4f5728cd2a8054e27165738ca 150 Gene3D G3DSA:3.10.180.10 14 149 8.9E-41 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_37215 f93a8cf4f5728cd2a8054e27165738ca 150 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 17 148 5.0E-41 T 12-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 AFR_37215 f93a8cf4f5728cd2a8054e27165738ca 150 SUPERFAMILY SSF54593 8 149 1.26E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 SMART SM00984 320 421 2.0E-36 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 SUPERFAMILY SSF52413 311 431 2.62E-33 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 416 4.2E-128 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 Gene3D G3DSA:3.40.50.720 233 437 4.2E-64 T 12-10-2018 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 Gene3D G3DSA:3.40.50.720 1 200 5.1E-69 T 12-10-2018 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 1.6E-59 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 SUPERFAMILY SSF51735 1 191 7.09E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 Gene3D G3DSA:1.20.5.100 202 231 1.1E-13 T 12-10-2018 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 PIRSF PIRSF500134 1 437 9.9E-152 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 PIRSF PIRSF000124 1 436 5.3E-120 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 SUPERFAMILY SSF48179 202 299 3.74E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 420 1.7E-24 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_16015 37d97cfaa5317e93f414210f031bf86a 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 295 4.1E-31 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFR_06970 424e8a70d37360568fd7cf82165864d3 138 SUPERFAMILY SSF103196 3 131 1.34E-36 T 12-10-2018 AFR_06970 424e8a70d37360568fd7cf82165864d3 138 Gene3D G3DSA:3.30.450.30 7 132 2.9E-42 T 12-10-2018 AFR_06970 424e8a70d37360568fd7cf82165864d3 138 SMART SM00960 12 102 5.7E-31 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_06970 424e8a70d37360568fd7cf82165864d3 138 Pfam PF03259 Roadblock/LC7 domain 12 102 1.6E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_05680 ad84dcb20fd5e827e1b165dc87485f26 286 Gene3D G3DSA:3.20.20.370 59 286 2.1E-60 T 12-10-2018 AFR_05680 ad84dcb20fd5e827e1b165dc87485f26 286 SUPERFAMILY SSF88713 92 278 1.33E-52 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_05680 ad84dcb20fd5e827e1b165dc87485f26 286 Pfam PF01522 Polysaccharide deacetylase 93 214 2.1E-32 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_09000 22048abed333b89b7b41f61ece23192d 202 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 97 199 3.0E-13 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 AFR_09000 22048abed333b89b7b41f61ece23192d 202 Gene3D G3DSA:3.30.1380.10 51 202 8.1E-20 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_09000 22048abed333b89b7b41f61ece23192d 202 SUPERFAMILY SSF55166 96 199 1.36E-22 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_22395 a5c2caac1cbe3dd5cdce02e745bd043e 198 SUPERFAMILY SSF55136 115 190 9.59E-10 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_22395 a5c2caac1cbe3dd5cdce02e745bd043e 198 Gene3D G3DSA:3.20.80.10 1 198 4.3E-73 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_22395 a5c2caac1cbe3dd5cdce02e745bd043e 198 Pfam PF06445 GyrI-like small molecule binding domain 20 195 6.9E-23 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain AFR_22395 a5c2caac1cbe3dd5cdce02e745bd043e 198 PIRSF PIRSF031644 2 198 1.0E-56 T 12-10-2018 IPR008319 Uncharacterised conserved protein UCP031644 AFR_05365 ffdf05e920322054fb64b65cdec8bb3d 249 SMART SM00987 65 239 7.6E-30 T 12-10-2018 AFR_05365 ffdf05e920322054fb64b65cdec8bb3d 249 SMART SM00986 65 239 7.6E-30 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_05365 ffdf05e920322054fb64b65cdec8bb3d 249 Pfam PF03167 Uracil DNA glycosylase superfamily 65 240 1.2E-26 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_05365 ffdf05e920322054fb64b65cdec8bb3d 249 SUPERFAMILY SSF52141 33 244 1.47E-42 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_05365 ffdf05e920322054fb64b65cdec8bb3d 249 Gene3D G3DSA:3.40.470.10 22 248 3.6E-64 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_28625 686eefa48c99f3094a8bbe3692e8a0fe 220 Gene3D G3DSA:1.10.10.10 124 220 2.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28625 686eefa48c99f3094a8bbe3692e8a0fe 220 Pfam PF00072 Response regulator receiver domain 3 113 4.3E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28625 686eefa48c99f3094a8bbe3692e8a0fe 220 SUPERFAMILY SSF52172 2 173 2.93E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28625 686eefa48c99f3094a8bbe3692e8a0fe 220 Gene3D G3DSA:3.40.50.2300 1 121 1.5E-29 T 12-10-2018 AFR_28625 686eefa48c99f3094a8bbe3692e8a0fe 220 SMART SM00862 145 217 3.0E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28625 686eefa48c99f3094a8bbe3692e8a0fe 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 8.3E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28625 686eefa48c99f3094a8bbe3692e8a0fe 220 SMART SM00448 1 112 4.8E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_37985 dc36c50c49fa02d0e5a30d1748926225 595 SMART SM00382 368 566 2.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37985 dc36c50c49fa02d0e5a30d1748926225 595 Gene3D G3DSA:1.20.1560.10 14 320 3.9E-13 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_37985 dc36c50c49fa02d0e5a30d1748926225 595 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_37985 dc36c50c49fa02d0e5a30d1748926225 595 Pfam PF00005 ABC transporter 359 514 1.3E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_37985 dc36c50c49fa02d0e5a30d1748926225 595 Gene3D G3DSA:3.40.50.300 334 595 2.7E-72 T 12-10-2018 AFR_37985 dc36c50c49fa02d0e5a30d1748926225 595 SUPERFAMILY SSF52540 334 590 2.22E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37985 dc36c50c49fa02d0e5a30d1748926225 595 SUPERFAMILY SSF90123 16 314 1.31E-19 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_18600 bc41c244c5455af6428a25ea85358e35 322 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 43 56 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFR_18600 bc41c244c5455af6428a25ea85358e35 322 Gene3D G3DSA:3.40.50.1100 14 308 1.9E-115 T 12-10-2018 AFR_18600 bc41c244c5455af6428a25ea85358e35 322 SUPERFAMILY SSF53686 4 312 1.19E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_18600 bc41c244c5455af6428a25ea85358e35 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 304 2.5E-81 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_18600 bc41c244c5455af6428a25ea85358e35 322 Gene3D G3DSA:3.40.50.1100 51 147 1.9E-115 T 12-10-2018 AFR_31020 72301f476870a3e2d7ab86eec038d4ae 232 Pfam PF00753 Metallo-beta-lactamase superfamily 11 205 9.3E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_31020 72301f476870a3e2d7ab86eec038d4ae 232 SMART SM00849 12 205 8.3E-33 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_31020 72301f476870a3e2d7ab86eec038d4ae 232 SUPERFAMILY SSF56281 8 222 1.7E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_31020 72301f476870a3e2d7ab86eec038d4ae 232 Gene3D G3DSA:3.60.15.10 2 227 2.2E-55 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_34405 5987ebf4c0c86dd5715585a07fa32089 329 Gene3D G3DSA:3.20.20.100 4 327 6.5E-109 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_34405 5987ebf4c0c86dd5715585a07fa32089 329 Pfam PF00248 Aldo/keto reductase family 19 312 6.8E-71 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_34405 5987ebf4c0c86dd5715585a07fa32089 329 SUPERFAMILY SSF51430 4 313 1.19E-94 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_13435 9b94ebd108edeacd40384356cca9a93f 191 SUPERFAMILY SSF52540 14 184 7.99E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13435 9b94ebd108edeacd40384356cca9a93f 191 Gene3D G3DSA:3.40.50.300 12 189 1.2E-12 T 12-10-2018 AFR_13435 9b94ebd108edeacd40384356cca9a93f 191 Pfam PF03029 Conserved hypothetical ATP binding protein 18 185 6.4E-26 T 12-10-2018 IPR004130 GPN-loop GTPase AFR_33515 4277c8cbfb4d8be7d70768afe3225c95 375 Pfam PF07730 Histidine kinase 187 248 2.5E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_33515 4277c8cbfb4d8be7d70768afe3225c95 375 SMART SM00387 286 375 4.0E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_33515 4277c8cbfb4d8be7d70768afe3225c95 375 PIRSF PIRSF037434 4 375 6.6E-73 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS AFR_33515 4277c8cbfb4d8be7d70768afe3225c95 375 SUPERFAMILY SSF55874 251 375 5.37E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33515 4277c8cbfb4d8be7d70768afe3225c95 375 Gene3D G3DSA:3.30.565.10 251 375 1.4E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_10550 439ef295bbbdebef7b02dc3a7dc87abf 307 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 24 306 39.563 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 AFR_10550 439ef295bbbdebef7b02dc3a7dc87abf 307 PIRSF PIRSF005052 24 307 7.0E-102 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 AFR_10550 439ef295bbbdebef7b02dc3a7dc87abf 307 SUPERFAMILY SSF52540 27 176 1.22E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10550 439ef295bbbdebef7b02dc3a7dc87abf 307 Pfam PF03668 P-loop ATPase protein family 25 307 4.8E-103 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 AFR_10550 439ef295bbbdebef7b02dc3a7dc87abf 307 Gene3D G3DSA:3.40.50.300 25 178 3.3E-8 T 12-10-2018 AFR_10855 8aa5dfb7c19aa062c3b25155835f4f9d 249 Pfam PF13560 Helix-turn-helix domain 2 62 8.0E-11 T 12-10-2018 AFR_10855 8aa5dfb7c19aa062c3b25155835f4f9d 249 Gene3D G3DSA:1.10.260.40 1 66 5.9E-11 T 12-10-2018 AFR_10855 8aa5dfb7c19aa062c3b25155835f4f9d 249 SUPERFAMILY SSF47413 2 56 5.09E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_10855 8aa5dfb7c19aa062c3b25155835f4f9d 249 SMART SM00530 4 59 3.6E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SMART SM00710 922 950 1100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SMART SM00710 899 921 6700.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SMART SM00710 836 858 3400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SMART SM00710 804 828 1700.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SMART SM00710 637 670 2900.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SMART SM00710 751 773 2100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SUPERFAMILY SSF49785 162 291 4.25E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 Gene3D G3DSA:2.60.120.260 440 583 5.5E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SUPERFAMILY SSF49785 306 423 2.92E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 Gene3D G3DSA:2.60.120.260 166 302 1.0E-33 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 Gene3D G3DSA:2.60.120.260 307 434 4.8E-19 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 Gene3D G3DSA:2.60.120.260 31 165 5.5E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SUPERFAMILY SSF49785 29 156 2.19E-19 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 Gene3D G3DSA:2.160.20.10 584 954 4.3E-25 T 12-10-2018 IPR012334 Pectin lyase fold AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 Pfam PF16990 Carbohydrate binding module (family 35) 31 159 1.4E-10 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 Pfam PF16990 Carbohydrate binding module (family 35) 167 292 1.1E-11 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 AFR_01375 2582a4bfa2dd0dd57f62dc01dbcb0b41 957 SUPERFAMILY SSF51126 580 920 1.43E-29 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_02205 6b293021c0f67e5b82458f7509922f31 218 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 178 218 1.9E-19 T 12-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_02205 6b293021c0f67e5b82458f7509922f31 218 SUPERFAMILY SSF50475 17 218 3.73E-64 T 12-10-2018 AFR_02205 6b293021c0f67e5b82458f7509922f31 218 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 124 5.5E-22 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_02205 6b293021c0f67e5b82458f7509922f31 218 Gene3D G3DSA:2.30.110.10 14 216 1.3E-79 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_02205 6b293021c0f67e5b82458f7509922f31 218 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 10 218 6.7E-80 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_02205 6b293021c0f67e5b82458f7509922f31 218 PIRSF PIRSF000190 3 218 1.6E-76 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_02205 6b293021c0f67e5b82458f7509922f31 218 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 14 218 38.082 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_02205 6b293021c0f67e5b82458f7509922f31 218 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 188 201 - T 12-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 8.0E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 SMART SM00421 148 205 1.4E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 5.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 5.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 5.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 SUPERFAMILY SSF52172 2 132 2.28E-30 T 12-10-2018 IPR011006 CheY-like superfamily AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 SUPERFAMILY SSF46894 140 211 1.63E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 Gene3D G3DSA:3.40.50.12740 2 211 2.3E-64 T 12-10-2018 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 SMART SM00448 2 117 6.8E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 Pfam PF00072 Response regulator receiver domain 4 118 7.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_25735 0d6be6cbc9178e85fad4375e951586cc 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_04945 d4c530b1ec819ebf3499e9c01707aa31 139 Pfam PF17252 Family of unknown function (DUF5319) 8 128 1.8E-50 T 12-10-2018 IPR035165 Protein of unknown function DUF5319 AFR_04945 d4c530b1ec819ebf3499e9c01707aa31 139 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 11 126 1.0E-31 T 12-10-2018 IPR035165 Protein of unknown function DUF5319 AFR_22885 a289ecc54ff01cc166eff631d76ae804 283 Pfam PF13560 Helix-turn-helix domain 5 84 2.3E-16 T 12-10-2018 AFR_22885 a289ecc54ff01cc166eff631d76ae804 283 Gene3D G3DSA:1.10.260.40 24 93 3.7E-8 T 12-10-2018 AFR_22885 a289ecc54ff01cc166eff631d76ae804 283 SUPERFAMILY SSF47413 29 80 1.04E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_22885 a289ecc54ff01cc166eff631d76ae804 283 Gene3D G3DSA:3.30.450.180 104 271 5.6E-7 T 12-10-2018 AFR_22885 a289ecc54ff01cc166eff631d76ae804 283 SMART SM00530 9 81 4.8E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_04765 1f019c4cebe9271512666bc5e199e6b3 137 SUPERFAMILY SSF103196 4 129 9.42E-34 T 12-10-2018 AFR_04765 1f019c4cebe9271512666bc5e199e6b3 137 Gene3D G3DSA:3.30.450.30 6 132 1.5E-41 T 12-10-2018 AFR_04765 1f019c4cebe9271512666bc5e199e6b3 137 Pfam PF03259 Roadblock/LC7 domain 11 101 5.6E-23 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_04765 1f019c4cebe9271512666bc5e199e6b3 137 SMART SM00960 11 101 4.0E-29 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_05660 c3da7230fa858ab15a136f9979476b68 835 Gene3D G3DSA:3.20.20.70 489 832 4.4E-48 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 493 833 1.6E-156 T 12-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 60 384 2.4E-144 T 12-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 SMART SM00729 63 296 1.7E-4 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 Hamap MF_01612 FO synthase subunit 2 [cofH]. 465 835 46.452 T 12-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 Pfam PF04055 Radical SAM superfamily 533 693 8.8E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 Pfam PF04055 Radical SAM superfamily 67 244 2.6E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 Hamap MF_01611 FO synthase subunit 1 [cofG]. 59 386 50.073 T 12-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 525 832 1.5E-107 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 SUPERFAMILY SSF102114 56 361 2.35E-37 T 12-10-2018 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 SUPERFAMILY SSF102114 496 800 6.93E-42 T 12-10-2018 AFR_05660 c3da7230fa858ab15a136f9979476b68 835 Gene3D G3DSA:3.20.20.70 1 309 3.7E-50 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_26770 b2d673dd00dbdafeedddb920d9e9646e 309 Pfam PF12006 Protein of unknown function (DUF3500) 6 294 3.6E-69 T 12-10-2018 IPR021889 Protein of unknown function DUF3500 AFR_35860 d04ef5e8c757e73a118e004691243ce3 173 Gene3D G3DSA:3.40.630.30 2 172 5.2E-41 T 12-10-2018 AFR_35860 d04ef5e8c757e73a118e004691243ce3 173 SUPERFAMILY SSF55729 1 155 6.45E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35860 d04ef5e8c757e73a118e004691243ce3 173 Pfam PF00583 Acetyltransferase (GNAT) family 48 145 1.3E-16 T 12-10-2018 IPR000182 GNAT domain AFR_30015 02f75774f71d8767ff1597b36960c0ee 236 Gene3D G3DSA:3.40.50.300 1 233 5.7E-94 T 12-10-2018 AFR_30015 02f75774f71d8767ff1597b36960c0ee 236 PIRSF PIRSF028756 1 235 4.7E-74 T 12-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 AFR_30015 02f75774f71d8767ff1597b36960c0ee 236 SUPERFAMILY SSF52540 35 228 1.22E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30015 02f75774f71d8767ff1597b36960c0ee 236 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 5 231 5.0E-81 T 12-10-2018 IPR022488 Polyphosphate kinase-2-related AFR_35605 6dd1cd043505ca21f2fc5efdfdfcbd2a 248 Gene3D G3DSA:3.40.50.300 4 248 1.2E-76 T 12-10-2018 AFR_35605 6dd1cd043505ca21f2fc5efdfdfcbd2a 248 Pfam PF00005 ABC transporter 23 171 5.5E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_35605 6dd1cd043505ca21f2fc5efdfdfcbd2a 248 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_35605 6dd1cd043505ca21f2fc5efdfdfcbd2a 248 PIRSF PIRSF039085 4 247 9.0E-111 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFR_35605 6dd1cd043505ca21f2fc5efdfdfcbd2a 248 SUPERFAMILY SSF52540 7 241 4.33E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35605 6dd1cd043505ca21f2fc5efdfdfcbd2a 248 SMART SM00382 32 226 2.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_31520 c9d3c247c6506aba7112b726f7a03397 515 SUPERFAMILY SSF51645 3 513 3.66E-182 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_31520 c9d3c247c6506aba7112b726f7a03397 515 Gene3D G3DSA:1.20.1220.12 395 515 7.7E-48 T 12-10-2018 AFR_31520 c9d3c247c6506aba7112b726f7a03397 515 Gene3D G3DSA:3.20.20.360 1 391 1.1E-183 T 12-10-2018 AFR_31520 c9d3c247c6506aba7112b726f7a03397 515 Pfam PF01274 Malate synthase 2 514 2.0E-196 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_31520 c9d3c247c6506aba7112b726f7a03397 515 PIRSF PIRSF001363 1 515 1.5E-236 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_31520 c9d3c247c6506aba7112b726f7a03397 515 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 4 514 6.2E-240 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_09815 6301b6fd52dc7628524fb5407968c60c 250 Pfam PF13460 NAD(P)H-binding 48 151 1.1E-8 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_09815 6301b6fd52dc7628524fb5407968c60c 250 Gene3D G3DSA:3.90.25.10 104 231 3.1E-39 T 12-10-2018 AFR_09815 6301b6fd52dc7628524fb5407968c60c 250 Gene3D G3DSA:3.40.50.720 34 229 3.1E-39 T 12-10-2018 AFR_09815 6301b6fd52dc7628524fb5407968c60c 250 SUPERFAMILY SSF51735 2 215 1.49E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_30665 4347e30f6627997fff68d55900d73b6c 232 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 139 184 1.0E-11 T 12-10-2018 IPR004176 Clp, N-terminal AFR_30665 4347e30f6627997fff68d55900d73b6c 232 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 67 110 2.8E-4 T 12-10-2018 IPR004176 Clp, N-terminal AFR_30665 4347e30f6627997fff68d55900d73b6c 232 SUPERFAMILY SSF81923 55 183 1.57E-18 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_30665 4347e30f6627997fff68d55900d73b6c 232 Gene3D G3DSA:1.10.1780.10 54 190 1.7E-30 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 362 373 5.8E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 235 254 5.8E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 541 568 5.8E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 434 456 5.8E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 99 705 3.0E-182 T 12-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 Gene3D G3DSA:3.20.70.20 62 711 3.5E-196 T 12-10-2018 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 56 139 3.6E-18 T 12-10-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 SUPERFAMILY SSF51998 160 699 1.46E-130 T 12-10-2018 AFR_35505 92a31d9d295c2c764396ea28375363d8 964 Pfam PF02867 Ribonucleotide reductase, barrel domain 160 695 7.4E-143 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 Pfam PF13519 von Willebrand factor type A domain 420 526 4.1E-15 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 Gene3D G3DSA:1.10.8.80 144 233 3.9E-30 T 12-10-2018 AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 Gene3D G3DSA:3.40.50.300 1 99 2.1E-28 T 12-10-2018 AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 SMART SM00327 416 585 4.5E-17 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 SUPERFAMILY SSF52540 3 224 1.51E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 Gene3D G3DSA:3.40.50.410 420 583 2.7E-22 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 SUPERFAMILY SSF53300 420 549 5.89E-22 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_26925 0db220ce47c9c187a21df4fed3c8c528 589 Pfam PF01078 Magnesium chelatase, subunit ChlI 9 79 1.6E-7 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 216 371 2.7E-30 T 12-10-2018 IPR000160 GGDEF domain AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 Gene3D G3DSA:3.20.20.450 388 641 1.9E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 SMART SM00267 208 375 1.9E-52 T 12-10-2018 IPR000160 GGDEF domain AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 Gene3D G3DSA:3.30.70.270 213 387 1.7E-48 T 12-10-2018 AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 Pfam PF00990 Diguanylate cyclase, GGDEF domain 218 370 7.4E-40 T 12-10-2018 IPR000160 GGDEF domain AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 Pfam PF00563 EAL domain 404 629 2.3E-66 T 12-10-2018 IPR001633 EAL domain AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 SMART SM00052 385 634 2.9E-97 T 12-10-2018 IPR001633 EAL domain AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 SUPERFAMILY SSF55073 223 374 6.59E-39 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_20405 abd9c0e1925eacb063cc1ae577f5f67b 652 SUPERFAMILY SSF141868 403 639 1.24E-80 T 12-10-2018 IPR035919 EAL domain superfamily AFR_08645 672bd5c27bf0bbdd9bc11a5d470acfeb 705 Pfam PF13245 AAA domain 187 536 1.1E-14 T 12-10-2018 AFR_08645 672bd5c27bf0bbdd9bc11a5d470acfeb 705 SUPERFAMILY SSF52540 176 699 2.39E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08645 672bd5c27bf0bbdd9bc11a5d470acfeb 705 Pfam PF13538 UvrD-like helicase C-terminal domain 651 697 1.5E-8 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain AFR_08645 672bd5c27bf0bbdd9bc11a5d470acfeb 705 Gene3D G3DSA:3.40.50.300 453 579 8.2E-12 T 12-10-2018 AFR_08645 672bd5c27bf0bbdd9bc11a5d470acfeb 705 Gene3D G3DSA:3.40.50.300 172 376 5.1E-10 T 12-10-2018 AFR_08645 672bd5c27bf0bbdd9bc11a5d470acfeb 705 Gene3D G3DSA:3.40.50.300 632 705 4.1E-7 T 12-10-2018 AFR_13610 08d0550b5ec4f04beb0ae3aba05f6af5 752 SUPERFAMILY SSF51126 457 667 3.93E-7 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_13610 08d0550b5ec4f04beb0ae3aba05f6af5 752 Gene3D G3DSA:2.60.120.260 46 176 3.9E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_13610 08d0550b5ec4f04beb0ae3aba05f6af5 752 Gene3D G3DSA:2.160.20.10 455 730 8.7E-12 T 12-10-2018 IPR012334 Pectin lyase fold AFR_13610 08d0550b5ec4f04beb0ae3aba05f6af5 752 Pfam PF00754 F5/8 type C domain 54 166 3.4E-25 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_13610 08d0550b5ec4f04beb0ae3aba05f6af5 752 SUPERFAMILY SSF49785 53 170 7.09E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_40625 a916a097f02162be0cc0ca6250191e21 475 Gene3D G3DSA:3.20.20.80 14 468 5.7E-184 T 12-10-2018 AFR_40625 a916a097f02162be0cc0ca6250191e21 475 TIGRFAM TIGR03356 BGL: beta-galactosidase 20 458 1.4E-185 T 12-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 AFR_40625 a916a097f02162be0cc0ca6250191e21 475 Pfam PF00232 Glycosyl hydrolase family 1 19 466 3.9E-170 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_40625 a916a097f02162be0cc0ca6250191e21 475 SUPERFAMILY SSF51445 19 469 6.35E-168 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_40625 a916a097f02162be0cc0ca6250191e21 475 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 24 38 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site AFR_40625 a916a097f02162be0cc0ca6250191e21 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 1.1E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_40625 a916a097f02162be0cc0ca6250191e21 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 1.1E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_40625 a916a097f02162be0cc0ca6250191e21 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 1.1E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_40625 a916a097f02162be0cc0ca6250191e21 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 301 315 1.1E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_40625 a916a097f02162be0cc0ca6250191e21 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 1.1E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 AFR_38185 9abeb1382bd4641d33483e007d0abe36 334 SMART SM00495 288 334 9.0E-5 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_38185 9abeb1382bd4641d33483e007d0abe36 334 Gene3D G3DSA:2.10.10.20 290 333 1.4E-14 T 12-10-2018 AFR_38185 9abeb1382bd4641d33483e007d0abe36 334 SUPERFAMILY SSF51055 290 333 1.7E-10 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_38185 9abeb1382bd4641d33483e007d0abe36 334 Pfam PF00722 Glycosyl hydrolases family 16 152 206 5.4E-8 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_38185 9abeb1382bd4641d33483e007d0abe36 334 Gene3D G3DSA:2.60.120.200 147 222 7.0E-14 T 12-10-2018 AFR_38185 9abeb1382bd4641d33483e007d0abe36 334 SUPERFAMILY SSF49899 39 222 1.68E-30 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_38185 9abeb1382bd4641d33483e007d0abe36 334 Gene3D G3DSA:2.60.120.200 42 146 8.7E-17 T 12-10-2018 AFR_15915 a47954185f1840ec9dcc80a5900c261f 366 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 22 360 1.2E-105 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_15915 a47954185f1840ec9dcc80a5900c261f 366 PIRSF PIRSF000390 4 366 2.0E-93 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_15915 a47954185f1840ec9dcc80a5900c261f 366 Gene3D G3DSA:3.40.640.10 1 244 2.5E-72 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_15915 a47954185f1840ec9dcc80a5900c261f 366 SUPERFAMILY SSF53383 24 364 1.34E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_15915 a47954185f1840ec9dcc80a5900c261f 366 Gene3D G3DSA:3.90.1150.10 246 365 5.5E-35 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_17595 b35969c3515752c2f7e6fbad394adc97 220 SUPERFAMILY SSF52499 15 213 8.37E-51 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_17595 b35969c3515752c2f7e6fbad394adc97 220 Pfam PF00857 Isochorismatase family 32 208 1.8E-38 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_17595 b35969c3515752c2f7e6fbad394adc97 220 Gene3D G3DSA:3.40.50.850 14 217 4.8E-65 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_14790 a17b4a3bd54384f01963f28cabd5a074 716 SUPERFAMILY SSF82866 443 679 1.01E-25 T 12-10-2018 AFR_14790 a17b4a3bd54384f01963f28cabd5a074 716 SUPERFAMILY SSF82866 121 332 8.76E-30 T 12-10-2018 AFR_14790 a17b4a3bd54384f01963f28cabd5a074 716 Gene3D G3DSA:1.20.1640.10 171 334 3.1E-5 T 12-10-2018 AFR_14790 a17b4a3bd54384f01963f28cabd5a074 716 Pfam PF03176 MMPL family 439 680 3.5E-29 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_14790 a17b4a3bd54384f01963f28cabd5a074 716 Pfam PF03176 MMPL family 47 359 1.1E-60 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_03825 a0d4d54de5326a40afe574996e16d592 371 Gene3D G3DSA:1.10.10.10 260 363 3.9E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03825 a0d4d54de5326a40afe574996e16d592 371 Pfam PF00196 Bacterial regulatory proteins, luxR family 299 349 7.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_03825 a0d4d54de5326a40afe574996e16d592 371 SUPERFAMILY SSF46894 290 351 7.48E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_03825 a0d4d54de5326a40afe574996e16d592 371 SMART SM00421 296 353 8.8E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 7.9E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 7.9E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 7.9E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 7.9E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 SMART SM00388 238 309 1.1E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 SUPERFAMILY SSF55874 308 451 3.01E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 Pfam PF00672 HAMP domain 184 233 2.0E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 SMART SM00387 347 453 2.8E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 Gene3D G3DSA:1.10.287.130 188 309 1.3E-22 T 12-10-2018 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 305 3.4E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 451 3.8E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 SUPERFAMILY SSF47384 221 307 9.42E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 Gene3D G3DSA:3.30.565.10 312 454 1.2E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 SMART SM00304 184 237 1.2E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_01100 fa31b7c7430234c11e580a9b4ee7886d 469 SUPERFAMILY SSF158472 187 234 6.93E-7 T 12-10-2018 AFR_03445 291ee15b774dbcc71446a95ced490e86 410 SUPERFAMILY SSF103473 7 391 5.23E-38 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_03445 291ee15b774dbcc71446a95ced490e86 410 Gene3D G3DSA:1.20.1250.20 3 385 1.6E-30 T 12-10-2018 AFR_03445 291ee15b774dbcc71446a95ced490e86 410 Pfam PF07690 Major Facilitator Superfamily 12 339 1.5E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_21470 b6af875633d3861532667dd8ae71fd8f 136 Gene3D G3DSA:3.10.180.10 2 136 4.9E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21470 b6af875633d3861532667dd8ae71fd8f 136 SUPERFAMILY SSF54593 5 133 5.77E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21470 b6af875633d3861532667dd8ae71fd8f 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 6.4E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_26535 7b4f73eaa881392e30d1f2be64d8a62c 235 SUPERFAMILY SSF56784 1 227 7.09E-37 T 12-10-2018 IPR036412 HAD-like superfamily AFR_26535 7b4f73eaa881392e30d1f2be64d8a62c 235 Pfam PF00702 haloacid dehalogenase-like hydrolase 1 176 1.8E-12 T 12-10-2018 AFR_26535 7b4f73eaa881392e30d1f2be64d8a62c 235 Gene3D G3DSA:3.40.50.1000 1 201 4.4E-33 T 12-10-2018 IPR023214 HAD superfamily AFR_26535 7b4f73eaa881392e30d1f2be64d8a62c 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.8E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26535 7b4f73eaa881392e30d1f2be64d8a62c 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 1.8E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26535 7b4f73eaa881392e30d1f2be64d8a62c 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.8E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_16570 0aa86113349aac70199fc8718010fc81 226 SMART SM01012 166 221 0.0014 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_16570 0aa86113349aac70199fc8718010fc81 226 Gene3D G3DSA:3.30.450.40 25 144 1.1E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_16570 0aa86113349aac70199fc8718010fc81 226 SUPERFAMILY SSF55781 36 135 3.6E-11 T 12-10-2018 AFR_16570 0aa86113349aac70199fc8718010fc81 226 Pfam PF13185 GAF domain 47 135 1.5E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_21340 e3465b1f76c58232359bd5b07058f51a 68 Pfam PF06902 Divergent 4Fe-4S mono-cluster 3 61 1.6E-13 T 12-10-2018 IPR010693 Divergent 4Fe-4S mono-cluster AFR_21340 e3465b1f76c58232359bd5b07058f51a 68 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 9.9E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_21340 e3465b1f76c58232359bd5b07058f51a 68 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 9.9E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_21340 e3465b1f76c58232359bd5b07058f51a 68 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 9.9E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_21340 e3465b1f76c58232359bd5b07058f51a 68 SUPERFAMILY SSF54862 4 61 6.7E-12 T 12-10-2018 AFR_21340 e3465b1f76c58232359bd5b07058f51a 68 Gene3D G3DSA:3.30.70.20 2 63 5.4E-18 T 12-10-2018 AFR_23135 42c03e2040b552422a23ddc43339baf8 110 Pfam PF13601 Winged helix DNA-binding domain 21 100 1.2E-19 T 12-10-2018 IPR027395 Winged helix DNA-binding domain AFR_23135 42c03e2040b552422a23ddc43339baf8 110 Gene3D G3DSA:1.10.10.10 11 104 2.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23135 42c03e2040b552422a23ddc43339baf8 110 SUPERFAMILY SSF46785 10 100 8.44E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_18580 4d9fe603617b981445e23368442c7556 397 SUPERFAMILY SSF55874 287 395 5.34E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_18580 4d9fe603617b981445e23368442c7556 397 Pfam PF07730 Histidine kinase 211 275 1.0E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_18580 4d9fe603617b981445e23368442c7556 397 Gene3D G3DSA:3.30.565.10 279 396 1.3E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13785 c8784d7e516bc8961c912080933325a3 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 145 227 6.7E-17 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_13785 c8784d7e516bc8961c912080933325a3 269 SMART SM00898 4 136 7.2E-23 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_13785 c8784d7e516bc8961c912080933325a3 269 SUPERFAMILY SSF46946 144 227 3.79E-19 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFR_13785 c8784d7e516bc8961c912080933325a3 269 SUPERFAMILY SSF81624 4 148 5.89E-21 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_13785 c8784d7e516bc8961c912080933325a3 269 Gene3D G3DSA:3.20.190.10 3 143 5.0E-26 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_13785 c8784d7e516bc8961c912080933325a3 269 SMART SM01232 144 234 2.1E-19 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_13785 c8784d7e516bc8961c912080933325a3 269 Gene3D G3DSA:1.10.8.50 144 269 9.4E-27 T 12-10-2018 AFR_13785 c8784d7e516bc8961c912080933325a3 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 3 135 2.8E-24 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_03320 c0c43447865251ca7f7913856aa2d5d8 297 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_03320 c0c43447865251ca7f7913856aa2d5d8 297 Pfam PF00005 ABC transporter 21 159 9.5E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03320 c0c43447865251ca7f7913856aa2d5d8 297 SMART SM00382 29 206 1.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03320 c0c43447865251ca7f7913856aa2d5d8 297 Gene3D G3DSA:3.40.50.300 1 229 8.7E-57 T 12-10-2018 AFR_03320 c0c43447865251ca7f7913856aa2d5d8 297 SUPERFAMILY SSF52540 4 218 1.96E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22485 79f4c3107f1b2f1b787339348df9745e 420 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 122 3.6E-19 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_22485 79f4c3107f1b2f1b787339348df9745e 420 SUPERFAMILY SSF51735 2 151 2.05E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_22485 79f4c3107f1b2f1b787339348df9745e 420 SUPERFAMILY SSF55347 130 380 1.44E-27 T 12-10-2018 AFR_22485 79f4c3107f1b2f1b787339348df9745e 420 Gene3D G3DSA:3.40.50.720 1 125 1.3E-25 T 12-10-2018 AFR_22485 79f4c3107f1b2f1b787339348df9745e 420 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 208 2.0E-7 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_25810 8d2f8541d17686c70494851859f67b62 160 SUPERFAMILY SSF55729 1 157 1.08E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_25810 8d2f8541d17686c70494851859f67b62 160 Pfam PF00583 Acetyltransferase (GNAT) family 45 148 2.1E-14 T 12-10-2018 IPR000182 GNAT domain AFR_25810 8d2f8541d17686c70494851859f67b62 160 Gene3D G3DSA:3.40.630.30 1 160 2.5E-27 T 12-10-2018 AFR_37825 019a3ac43fafe7e612ade587da6d56f3 373 SMART SM00636 79 354 1.2E-6 T 12-10-2018 IPR011583 Chitinase II GO:0008061 AFR_37825 019a3ac43fafe7e612ade587da6d56f3 373 Gene3D G3DSA:3.20.20.80 77 372 6.2E-83 T 12-10-2018 AFR_37825 019a3ac43fafe7e612ade587da6d56f3 373 ProSitePatterns PS01095 Chitinases family 18 active site. 190 198 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_37825 019a3ac43fafe7e612ade587da6d56f3 373 Gene3D G3DSA:2.10.10.20 1 35 3.3E-9 T 12-10-2018 AFR_37825 019a3ac43fafe7e612ade587da6d56f3 373 SUPERFAMILY SSF51445 76 361 9.49E-57 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_37825 019a3ac43fafe7e612ade587da6d56f3 373 Pfam PF00704 Glycosyl hydrolases family 18 82 354 1.4E-28 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_37825 019a3ac43fafe7e612ade587da6d56f3 373 SUPERFAMILY SSF51055 1 34 8.44E-7 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_38280 3e90d5715d4f59315d694f5c20621133 365 SUPERFAMILY SSF74853 241 357 1.44E-15 T 12-10-2018 IPR036415 Lamin tail domain superfamily AFR_38280 3e90d5715d4f59315d694f5c20621133 365 Pfam PF00932 Lamin Tail Domain 238 357 3.3E-24 T 12-10-2018 IPR001322 Lamin tail domain AFR_28275 b9aef887b3321699d62b85241ddcef4f 559 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 1 545 42.699 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 AFR_28275 b9aef887b3321699d62b85241ddcef4f 559 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 10 528 4.3E-110 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 AFR_39675 b681dc4c90c6a33485a6c5d4f727d132 444 Pfam PF13416 Bacterial extracellular solute-binding protein 72 379 1.6E-36 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_39675 b681dc4c90c6a33485a6c5d4f727d132 444 SUPERFAMILY SSF53850 56 432 1.47E-73 T 12-10-2018 AFR_39675 b681dc4c90c6a33485a6c5d4f727d132 444 Gene3D G3DSA:3.40.190.10 52 442 2.1E-84 T 12-10-2018 AFR_07005 bf4e436affdf5a279a2a4fcc43730768 377 SUPERFAMILY SSF81606 173 350 4.05E-10 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_07005 bf4e436affdf5a279a2a4fcc43730768 377 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 185 371 7.3E-30 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_07005 bf4e436affdf5a279a2a4fcc43730768 377 Gene3D G3DSA:3.60.40.10 154 376 2.2E-38 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_07005 bf4e436affdf5a279a2a4fcc43730768 377 SMART SM00331 158 371 1.1E-15 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_29385 88ae98d1902bede95ede2a76bb028ea0 384 Pfam PF12146 Serine aminopeptidase, S33 159 251 2.1E-9 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFR_29385 88ae98d1902bede95ede2a76bb028ea0 384 Gene3D G3DSA:3.40.50.1820 22 372 2.9E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29385 88ae98d1902bede95ede2a76bb028ea0 384 SUPERFAMILY SSF53474 41 372 5.22E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28430 0788ac1669ef4449493c49bf897284f8 481 SUPERFAMILY SSF53649 29 460 2.62E-101 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_28430 0788ac1669ef4449493c49bf897284f8 481 ProSitePatterns PS00523 Sulfatases signature 1. 70 82 - T 12-10-2018 IPR024607 Sulfatase, conserved site AFR_28430 0788ac1669ef4449493c49bf897284f8 481 Gene3D G3DSA:3.40.720.10 30 446 7.4E-101 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_28430 0788ac1669ef4449493c49bf897284f8 481 Pfam PF00884 Sulfatase 31 359 3.4E-52 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 AFR_28430 0788ac1669ef4449493c49bf897284f8 481 PIRSF PIRSF036666 22 479 2.8E-86 T 12-10-2018 IPR012251 N-acetylglucosamine-6-sulfatase GO:0008449|GO:0030203 KEGG: 00531+3.1.6.14|Reactome: R-HSA-2022857|Reactome: R-HSA-2206305|Reactome: R-HSA-432720|Reactome: R-HSA-6798695 AFR_18505 6a41abbb79312320c64510cfc452045f 279 Pfam PF01061 ABC-2 type transporter 27 242 6.3E-38 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_18505 6a41abbb79312320c64510cfc452045f 279 PIRSF PIRSF006648 1 278 1.1E-57 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_18505 6a41abbb79312320c64510cfc452045f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 201 220 1.1E-7 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_18505 6a41abbb79312320c64510cfc452045f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 221 240 1.1E-7 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_18505 6a41abbb79312320c64510cfc452045f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 47 68 1.1E-7 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_37285 498c338f64796036fae022cebe23dc90 291 Pfam PF00005 ABC transporter 22 169 3.3E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_37285 498c338f64796036fae022cebe23dc90 291 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_37285 498c338f64796036fae022cebe23dc90 291 SUPERFAMILY SSF52540 4 231 5.01E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37285 498c338f64796036fae022cebe23dc90 291 SMART SM00382 30 226 5.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37285 498c338f64796036fae022cebe23dc90 291 Gene3D G3DSA:3.40.50.300 1 242 3.6E-59 T 12-10-2018 AFR_11255 ffcf52a8bf11edcd8e6c73810b5b88f9 198 Pfam PF03029 Conserved hypothetical ATP binding protein 18 185 3.9E-26 T 12-10-2018 IPR004130 GPN-loop GTPase AFR_11255 ffcf52a8bf11edcd8e6c73810b5b88f9 198 SUPERFAMILY SSF52540 14 188 8.21E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11255 ffcf52a8bf11edcd8e6c73810b5b88f9 198 Gene3D G3DSA:3.40.50.300 11 188 7.1E-14 T 12-10-2018 AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 Gene3D G3DSA:3.30.479.30 50 182 1.4E-44 T 12-10-2018 AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 SMART SM00244 22 180 1.3E-53 T 12-10-2018 IPR001107 Band 7 domain AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 SUPERFAMILY SSF117892 53 187 1.2E-39 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 Pfam PF01145 SPFH domain / Band 7 family 27 195 2.5E-33 T 12-10-2018 IPR001107 Band 7 domain AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 ProSitePatterns PS01270 Band 7 protein family signature. 136 164 - T 12-10-2018 IPR018080 Band 7/stomatin-like, conserved site AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 PRINTS PR00721 Stomatin signature 29 51 2.3E-32 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 PRINTS PR00721 Stomatin signature 77 98 2.3E-32 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 PRINTS PR00721 Stomatin signature 132 155 2.3E-32 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 PRINTS PR00721 Stomatin signature 175 196 2.3E-32 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 PRINTS PR00721 Stomatin signature 112 129 2.3E-32 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFR_11125 bc015cc489b6b63b35df6bc5d9e369ab 371 PRINTS PR00721 Stomatin signature 156 174 2.3E-32 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFR_00665 63af9cf3697bb8608df69d1330aa1de6 322 SUPERFAMILY SSF52540 75 318 2.78E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00665 63af9cf3697bb8608df69d1330aa1de6 322 Gene3D G3DSA:3.40.50.300 75 318 2.4E-24 T 12-10-2018 AFR_22850 45fb455f371b9d7e4bd05a4b20d3e04f 275 Gene3D G3DSA:3.40.50.1820 12 273 1.1E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22850 45fb455f371b9d7e4bd05a4b20d3e04f 275 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 123 135 - T 12-10-2018 IPR033140 Lipase, GDXG, putative serine active site AFR_22850 45fb455f371b9d7e4bd05a4b20d3e04f 275 SUPERFAMILY SSF53474 31 273 2.4E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22850 45fb455f371b9d7e4bd05a4b20d3e04f 275 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 58 74 - T 12-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 AFR_22850 45fb455f371b9d7e4bd05a4b20d3e04f 275 Pfam PF07859 alpha/beta hydrolase fold 58 234 7.2E-44 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_31005 13a0d4515fadf265d4b08094224cf398 245 SUPERFAMILY SSF51735 2 236 2.62E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_31005 13a0d4515fadf265d4b08094224cf398 245 Gene3D G3DSA:3.40.50.720 4 243 3.8E-64 T 12-10-2018 AFR_31005 13a0d4515fadf265d4b08094224cf398 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.7E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31005 13a0d4515fadf265d4b08094224cf398 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.7E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31005 13a0d4515fadf265d4b08094224cf398 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.7E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31005 13a0d4515fadf265d4b08094224cf398 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.7E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31005 13a0d4515fadf265d4b08094224cf398 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.7E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31005 13a0d4515fadf265d4b08094224cf398 245 Pfam PF00106 short chain dehydrogenase 7 195 9.4E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31005 13a0d4515fadf265d4b08094224cf398 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_31005 13a0d4515fadf265d4b08094224cf398 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 0.0022 T 12-10-2018 AFR_28230 63a46b9bed7b9f2cfbf13e6d8ed1d691 207 SMART SM00421 140 197 4.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28230 63a46b9bed7b9f2cfbf13e6d8ed1d691 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 4.2E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28230 63a46b9bed7b9f2cfbf13e6d8ed1d691 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 4.2E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28230 63a46b9bed7b9f2cfbf13e6d8ed1d691 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 4.2E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28230 63a46b9bed7b9f2cfbf13e6d8ed1d691 207 Gene3D G3DSA:1.10.10.10 61 206 3.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28230 63a46b9bed7b9f2cfbf13e6d8ed1d691 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 193 5.8E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28230 63a46b9bed7b9f2cfbf13e6d8ed1d691 207 SUPERFAMILY SSF46894 129 203 3.74E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_24730 97b0305e27caefe613af09fcd86eb336 356 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 207 303 7.1E-6 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 AFR_24730 97b0305e27caefe613af09fcd86eb336 356 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 20 157 8.3E-7 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 AFR_24730 97b0305e27caefe613af09fcd86eb336 356 Gene3D G3DSA:3.40.50.1820 13 344 7.1E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_24730 97b0305e27caefe613af09fcd86eb336 356 SUPERFAMILY SSF53474 49 340 1.02E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22965 98d44f5b4a8c853ce4bb6b51560d13f8 181 Gene3D G3DSA:3.40.630.30 3 166 1.4E-37 T 12-10-2018 AFR_22965 98d44f5b4a8c853ce4bb6b51560d13f8 181 SUPERFAMILY SSF55729 7 150 1.71E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_22965 98d44f5b4a8c853ce4bb6b51560d13f8 181 Pfam PF13302 Acetyltransferase (GNAT) domain 11 149 2.1E-26 T 12-10-2018 IPR000182 GNAT domain AFR_38065 a5a3574060f574795db9a83892cfcd41 258 Pfam PF01903 CbiX 146 220 5.0E-7 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFR_38065 a5a3574060f574795db9a83892cfcd41 258 Pfam PF01903 CbiX 13 108 2.6E-14 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFR_38065 a5a3574060f574795db9a83892cfcd41 258 Gene3D G3DSA:3.40.50.1400 5 130 3.3E-24 T 12-10-2018 AFR_38065 a5a3574060f574795db9a83892cfcd41 258 Gene3D G3DSA:3.40.50.1400 136 250 2.7E-17 T 12-10-2018 AFR_38065 a5a3574060f574795db9a83892cfcd41 258 SUPERFAMILY SSF53800 6 247 7.96E-35 T 12-10-2018 AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 SMART SM00344 1 108 2.2E-34 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 Gene3D G3DSA:3.30.70.920 52 143 9.6E-18 T 12-10-2018 AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.3E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.8E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.8E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.8E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 Gene3D G3DSA:1.10.10.10 2 51 9.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 Pfam PF01037 Lrp/AsnC ligand binding domain 75 138 7.7E-14 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 SUPERFAMILY SSF46785 1 60 5.73E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01430 58dde39a638ea13b432d692f7d0326e6 153 SUPERFAMILY SSF54909 61 145 7.51E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_37875 1904abada344a2d092d427d7476486d7 403 Gene3D G3DSA:3.40.640.10 62 312 6.4E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_37875 1904abada344a2d092d427d7476486d7 403 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 227 264 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_37875 1904abada344a2d092d427d7476486d7 403 Gene3D G3DSA:3.90.1150.10 17 394 6.4E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_37875 1904abada344a2d092d427d7476486d7 403 PIRSF PIRSF000521 10 159 4.2E-7 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_37875 1904abada344a2d092d427d7476486d7 403 PIRSF PIRSF000521 180 403 5.7E-28 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_37875 1904abada344a2d092d427d7476486d7 403 SUPERFAMILY SSF53383 10 402 3.81E-117 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_37875 1904abada344a2d092d427d7476486d7 403 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 12 400 6.8E-149 T 12-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFR_37875 1904abada344a2d092d427d7476486d7 403 Pfam PF00202 Aminotransferase class-III 20 402 7.2E-114 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_24250 a845d9f0689926a21589641f876a6278 362 SUPERFAMILY SSF55931 146 358 1.28E-8 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_24250 a845d9f0689926a21589641f876a6278 362 Gene3D G3DSA:3.30.590.20 66 361 3.6E-36 T 12-10-2018 AFR_24250 a845d9f0689926a21589641f876a6278 362 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 121 279 1.5E-22 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_34025 67962e8a310bdaf572e2ea84ca8dc81f 396 Gene3D G3DSA:3.40.630.30 132 392 1.9E-49 T 12-10-2018 AFR_34025 67962e8a310bdaf572e2ea84ca8dc81f 396 SUPERFAMILY SSF55718 307 394 1.14E-7 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_34025 67962e8a310bdaf572e2ea84ca8dc81f 396 Pfam PF13527 Acetyltransferase (GNAT) domain 3 129 2.1E-24 T 12-10-2018 AFR_34025 67962e8a310bdaf572e2ea84ca8dc81f 396 Pfam PF13530 Sterol carrier protein domain 198 392 1.6E-15 T 12-10-2018 IPR025559 Enhanced intracellular survival protein domain AFR_34025 67962e8a310bdaf572e2ea84ca8dc81f 396 Gene3D G3DSA:3.40.630.30 10 295 1.9E-49 T 12-10-2018 AFR_34025 67962e8a310bdaf572e2ea84ca8dc81f 396 SUPERFAMILY SSF55729 1 276 2.78E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_34025 67962e8a310bdaf572e2ea84ca8dc81f 396 Gene3D G3DSA:3.30.1050.10 296 386 1.9E-49 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_12770 ec363153520f9044e287ea2b6c1e9b2c 287 Gene3D G3DSA:1.10.260.40 23 81 2.5E-6 T 12-10-2018 AFR_12770 ec363153520f9044e287ea2b6c1e9b2c 287 Pfam PF13560 Helix-turn-helix domain 5 84 4.0E-17 T 12-10-2018 AFR_12770 ec363153520f9044e287ea2b6c1e9b2c 287 SUPERFAMILY SSF47413 27 80 7.41E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_12770 ec363153520f9044e287ea2b6c1e9b2c 287 SMART SM00530 9 81 1.7E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_15770 37827574a76f8b682340bbb797f98748 187 Pfam PF11706 CGNR zinc finger 137 178 3.9E-16 T 12-10-2018 IPR021005 Zinc finger, CGNR AFR_15770 37827574a76f8b682340bbb797f98748 187 Pfam PF07336 Putative stress-induced transcription regulator 12 110 6.0E-15 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator AFR_15770 37827574a76f8b682340bbb797f98748 187 Gene3D G3DSA:1.10.3300.10 6 182 4.1E-24 T 12-10-2018 IPR023286 ABATE domain superfamily AFR_15770 37827574a76f8b682340bbb797f98748 187 SUPERFAMILY SSF160904 8 178 7.06E-37 T 12-10-2018 AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 131 8.4E-11 T 12-10-2018 AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 Gene3D G3DSA:3.30.565.10 2 201 1.3E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 PRINTS PR00775 90kDa heat shock protein signature 22 44 2.3E-12 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 PRINTS PR00775 90kDa heat shock protein signature 1 21 2.3E-12 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 PRINTS PR00775 90kDa heat shock protein signature 104 126 2.3E-12 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 Pfam PF00183 Hsp90 protein 255 322 2.3E-6 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 Gene3D G3DSA:3.30.230.80 243 353 5.4E-12 T 12-10-2018 AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 SUPERFAMILY SSF55874 4 195 3.93E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 SUPERFAMILY SSF54211 220 420 1.29E-33 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 SMART SM00387 19 165 0.0037 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 PIRSF PIRSF002583 1 216 1.5E-50 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFR_00155 9c210f90af84a9b8fd8faadfc87f884e 586 PIRSF PIRSF002583 204 584 1.6E-33 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFR_10035 b9f8f9248cc6ed921eb1f61aca69ea9b 230 Hamap MF_01197 Cell division protein SepF [sepF]. 1 221 21.784 T 12-10-2018 IPR023052 Cell division protein SepF GO:0090529 AFR_10035 b9f8f9248cc6ed921eb1f61aca69ea9b 230 Pfam PF04472 Cell division protein SepF 142 213 2.9E-25 T 12-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 AFR_10035 b9f8f9248cc6ed921eb1f61aca69ea9b 230 Gene3D G3DSA:3.30.110.150 137 221 1.1E-27 T 12-10-2018 IPR038594 SepF-like superfamily AFR_17825 ee072fcf9aa2c28991fb504a5102e23b 255 SUPERFAMILY SSF110221 120 238 1.24E-31 T 12-10-2018 IPR036195 Alpha-L-arabinofuranosidase B, arabinose-binding domain superfamily GO:0046373|GO:0046556 AFR_17825 ee072fcf9aa2c28991fb504a5102e23b 255 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 125 241 2.7E-32 T 12-10-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 AFR_17825 ee072fcf9aa2c28991fb504a5102e23b 255 Gene3D G3DSA:2.80.10.50 115 251 9.2E-38 T 12-10-2018 AFR_39005 f2efc41e7eeb0beaea23fa91983c3501 120 SUPERFAMILY SSF50729 3 118 1.17E-20 T 12-10-2018 AFR_39005 f2efc41e7eeb0beaea23fa91983c3501 120 Gene3D G3DSA:2.30.29.50 2 119 8.8E-11 T 12-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily AFR_39005 f2efc41e7eeb0beaea23fa91983c3501 120 Pfam PF08000 Bacterial PH domain 14 118 3.6E-8 T 12-10-2018 IPR012544 Bacterial Pleckstrin homology domain AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 SUPERFAMILY SSF53756 188 504 2.04E-57 T 12-10-2018 AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 Pfam PF13242 HAD-hyrolase-like 98 162 1.4E-11 T 12-10-2018 AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 Gene3D G3DSA:3.40.50.2000 187 336 4.0E-7 T 12-10-2018 AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 7 144 1.6E-30 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 SUPERFAMILY SSF56784 6 172 1.27E-42 T 12-10-2018 IPR036412 HAD-like superfamily AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 258 472 3.8E-19 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 7 144 4.7E-31 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 Gene3D G3DSA:3.40.50.1000 6 176 8.2E-43 T 12-10-2018 IPR023214 HAD superfamily AFR_16605 4ec6a65889cb976666e8ac6bdb7177d7 519 Gene3D G3DSA:3.40.50.2000 345 507 4.0E-31 T 12-10-2018 AFR_12760 d8cfda3f858dc9cdd819ad4ee5a4cf8d 209 SUPERFAMILY SSF48498 83 192 1.71E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12760 d8cfda3f858dc9cdd819ad4ee5a4cf8d 209 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 188 4.0E-26 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_12760 d8cfda3f858dc9cdd819ad4ee5a4cf8d 209 SUPERFAMILY SSF46689 14 74 1.49E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12760 d8cfda3f858dc9cdd819ad4ee5a4cf8d 209 Gene3D G3DSA:1.10.10.60 9 61 5.2E-18 T 12-10-2018 AFR_12760 d8cfda3f858dc9cdd819ad4ee5a4cf8d 209 Gene3D G3DSA:1.10.357.10 62 197 5.3E-27 T 12-10-2018 AFR_12760 d8cfda3f858dc9cdd819ad4ee5a4cf8d 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.5E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_34730 d30e61f2149815dc01928fbd2d3639fe 310 SUPERFAMILY SSF69304 45 300 3.53E-6 T 12-10-2018 AFR_27865 47a1d562ccb62c56892075f637ef3788 413 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 109 139 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 AFR_27865 47a1d562ccb62c56892075f637ef3788 413 Gene3D G3DSA:3.40.50.1820 17 398 2.9E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_27865 47a1d562ccb62c56892075f637ef3788 413 SUPERFAMILY SSF53474 36 405 6.02E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_27865 47a1d562ccb62c56892075f637ef3788 413 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 130 144 1.3E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_27865 47a1d562ccb62c56892075f637ef3788 413 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 42 50 1.3E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_27865 47a1d562ccb62c56892075f637ef3788 413 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 72 83 1.3E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_27865 47a1d562ccb62c56892075f637ef3788 413 Pfam PF00561 alpha/beta hydrolase fold 40 183 1.3E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_18780 1c1268717e02b5a26efaa1bcabb04be4 261 SUPERFAMILY SSF51735 2 135 1.11E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_18780 1c1268717e02b5a26efaa1bcabb04be4 261 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 132 1.2E-18 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFR_18780 1c1268717e02b5a26efaa1bcabb04be4 261 Gene3D G3DSA:3.40.50.720 1 132 3.2E-25 T 12-10-2018 AFR_18780 1c1268717e02b5a26efaa1bcabb04be4 261 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 140 256 2.1E-12 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFR_18780 1c1268717e02b5a26efaa1bcabb04be4 261 Gene3D G3DSA:1.10.1040.10 133 260 8.3E-25 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_18780 1c1268717e02b5a26efaa1bcabb04be4 261 PIRSF PIRSF000103 1 261 4.1E-46 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFR_18780 1c1268717e02b5a26efaa1bcabb04be4 261 SUPERFAMILY SSF48179 136 257 1.7E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_38100 8b197c37e2c2d5184490f4983f00b588 344 SUPERFAMILY SSF53697 3 341 3.39E-71 T 12-10-2018 AFR_38100 8b197c37e2c2d5184490f4983f00b588 344 Pfam PF01380 SIS domain 36 161 2.0E-17 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_38100 8b197c37e2c2d5184490f4983f00b588 344 Pfam PF01380 SIS domain 204 285 1.7E-11 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_38100 8b197c37e2c2d5184490f4983f00b588 344 Gene3D G3DSA:3.40.50.10490 1 187 4.5E-47 T 12-10-2018 AFR_38100 8b197c37e2c2d5184490f4983f00b588 344 Gene3D G3DSA:3.40.50.10490 193 343 1.1E-34 T 12-10-2018 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 76 650 1.2E-197 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 344 550 7.7E-37 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 SUPERFAMILY SSF52954 550 655 4.08E-28 T 12-10-2018 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 SUPERFAMILY SSF55681 261 546 2.58E-92 T 12-10-2018 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 SMART SM00863 182 237 6.0E-18 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 PRINTS PR01047 Threonyl-tRNA synthetase signature 555 567 4.4E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 PRINTS PR01047 Threonyl-tRNA synthetase signature 382 405 4.4E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 PRINTS PR01047 Threonyl-tRNA synthetase signature 349 377 4.4E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 PRINTS PR01047 Threonyl-tRNA synthetase signature 528 541 4.4E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 PRINTS PR01047 Threonyl-tRNA synthetase signature 485 513 4.4E-52 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 SUPERFAMILY SSF55186 67 258 5.89E-51 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Gene3D G3DSA:3.30.930.10 243 553 5.0E-118 T 12-10-2018 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Pfam PF03129 Anticodon binding domain 562 650 9.3E-18 T 12-10-2018 IPR004154 Anticodon-binding AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 195 237 1.2E-12 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 70 655 32.898 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Gene3D G3DSA:3.30.980.10 73 240 5.2E-56 T 12-10-2018 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Gene3D G3DSA:3.30.54.20 134 205 5.2E-56 T 12-10-2018 AFR_31165 543fd63040718acb6ff68c895fb0fb05 664 Gene3D G3DSA:3.40.50.800 554 659 2.3E-25 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFR_20485 df1f56528dfb8217d1d298652fbfdb5d 194 Gene3D G3DSA:1.10.357.10 6 193 1.3E-47 T 12-10-2018 AFR_20485 df1f56528dfb8217d1d298652fbfdb5d 194 SUPERFAMILY SSF46689 12 83 2.54E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_20485 df1f56528dfb8217d1d298652fbfdb5d 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.8E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_20485 df1f56528dfb8217d1d298652fbfdb5d 194 SUPERFAMILY SSF48498 87 190 3.24E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02165 c462d13ee4e87092fde91d88a6c51bb3 220 Pfam PF13563 2'-5' RNA ligase superfamily 90 207 2.3E-13 T 12-10-2018 AFR_02165 c462d13ee4e87092fde91d88a6c51bb3 220 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 82 219 3.0E-27 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AFR_02165 c462d13ee4e87092fde91d88a6c51bb3 220 Gene3D G3DSA:3.90.1140.10 30 220 9.0E-39 T 12-10-2018 AFR_02165 c462d13ee4e87092fde91d88a6c51bb3 220 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 30 219 16.012 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AFR_02165 c462d13ee4e87092fde91d88a6c51bb3 220 SUPERFAMILY SSF55144 31 220 1.71E-26 T 12-10-2018 IPR009097 Cyclic phosphodiesterase AFR_07425 695ab457d1d6a7f90ce22ae26686b0c5 362 SUPERFAMILY SSF82861 118 172 6.8E-12 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFR_07425 695ab457d1d6a7f90ce22ae26686b0c5 362 Gene3D G3DSA:3.30.70.100 240 328 3.4E-14 T 12-10-2018 AFR_07425 695ab457d1d6a7f90ce22ae26686b0c5 362 Pfam PF00924 Mechanosensitive ion channel 133 329 2.0E-34 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFR_07425 695ab457d1d6a7f90ce22ae26686b0c5 362 SUPERFAMILY SSF50182 174 231 7.52E-11 T 12-10-2018 IPR010920 LSM domain superfamily AFR_07425 695ab457d1d6a7f90ce22ae26686b0c5 362 Gene3D G3DSA:2.30.30.60 189 238 1.1E-15 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily AFR_07425 695ab457d1d6a7f90ce22ae26686b0c5 362 SUPERFAMILY SSF82689 238 329 7.45E-5 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 SUPERFAMILY SSF46894 142 216 2.45E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 Gene3D G3DSA:3.40.50.12740 3 215 2.9E-71 T 12-10-2018 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 SMART SM00421 152 209 9.7E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 5.8E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 SMART SM00448 3 116 5.7E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 Pfam PF00072 Response regulator receiver domain 5 117 1.4E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_13735 d37f9b941116ecfb747c80cfb1448173 219 SUPERFAMILY SSF52172 2 135 1.01E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_17250 6ba45eb63f10b3ffc0657479be81258d 135 Gene3D G3DSA:2.60.40.2880 41 126 6.3E-6 T 12-10-2018 IPR038468 Transport accessory protein MmpS, soluble domain superfamily AFR_34400 5480ec148079d2409b05d6380bd145aa 292 SUPERFAMILY SSF46689 181 230 5.84E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_34400 5480ec148079d2409b05d6380bd145aa 292 Gene3D G3DSA:1.10.10.60 176 283 1.8E-27 T 12-10-2018 AFR_34400 5480ec148079d2409b05d6380bd145aa 292 Pfam PF06719 AraC-type transcriptional regulator N-terminus 22 168 1.1E-32 T 12-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal AFR_34400 5480ec148079d2409b05d6380bd145aa 292 SMART SM00342 197 280 1.1E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_34400 5480ec148079d2409b05d6380bd145aa 292 Pfam PF12833 Helix-turn-helix domain 203 278 3.8E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_34400 5480ec148079d2409b05d6380bd145aa 292 SUPERFAMILY SSF46689 233 279 2.22E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_09805 67e5303ab282033d8b63864fcbcbe62f 278 SUPERFAMILY SSF53850 59 263 1.74E-41 T 12-10-2018 AFR_09805 67e5303ab282033d8b63864fcbcbe62f 278 Gene3D G3DSA:1.10.10.10 1 58 4.0E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_09805 67e5303ab282033d8b63864fcbcbe62f 278 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 31 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_09805 67e5303ab282033d8b63864fcbcbe62f 278 Gene3D G3DSA:3.40.190.290 59 266 6.3E-55 T 12-10-2018 AFR_09805 67e5303ab282033d8b63864fcbcbe62f 278 Pfam PF03466 LysR substrate binding domain 58 262 1.7E-46 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_09805 67e5303ab282033d8b63864fcbcbe62f 278 SUPERFAMILY SSF46785 2 80 1.09E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 Pfam PF00406 Adenylate kinase 5 190 1.7E-54 T 12-10-2018 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 49.706 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 PRINTS PR00094 Adenylate kinase signature 177 191 2.0E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 PRINTS PR00094 Adenylate kinase signature 81 97 2.0E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 PRINTS PR00094 Adenylate kinase signature 4 17 2.0E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 PRINTS PR00094 Adenylate kinase signature 32 46 2.0E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 PRINTS PR00094 Adenylate kinase signature 160 175 2.0E-33 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 SUPERFAMILY SSF52540 4 210 1.57E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.4E-13 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 Gene3D G3DSA:3.40.50.300 1 212 5.0E-75 T 12-10-2018 AFR_04610 65b5ddf2f1a306a4974d9261482e98f5 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 211 1.9E-74 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFR_32495 001e3d37f53a9939ebf8cf3f0c234b19 156 Pfam PF02566 OsmC-like protein 48 146 4.1E-13 T 12-10-2018 IPR003718 OsmC/Ohr family AFR_32495 001e3d37f53a9939ebf8cf3f0c234b19 156 SUPERFAMILY SSF82784 5 146 7.98E-28 T 12-10-2018 IPR036102 OsmC/Ohr superfamily AFR_32495 001e3d37f53a9939ebf8cf3f0c234b19 156 Gene3D G3DSA:3.30.300.20 1 147 2.2E-35 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_08260 6c0879bd96b5a13fc3a8e32859c5feff 234 Pfam PF00155 Aminotransferase class I and II 4 221 6.2E-33 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_08260 6c0879bd96b5a13fc3a8e32859c5feff 234 Gene3D G3DSA:3.90.1150.10 135 226 2.0E-12 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_08260 6c0879bd96b5a13fc3a8e32859c5feff 234 SUPERFAMILY SSF53383 2 224 6.74E-50 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_08260 6c0879bd96b5a13fc3a8e32859c5feff 234 Gene3D G3DSA:3.40.640.10 1 134 9.5E-37 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_08260 6c0879bd96b5a13fc3a8e32859c5feff 234 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 87 96 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFR_35780 8601d8d032543665c9cb42128f993100 263 SMART SM00898 2 114 6.7E-17 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_35780 8601d8d032543665c9cb42128f993100 263 Gene3D G3DSA:1.10.8.50 129 260 2.0E-33 T 12-10-2018 AFR_35780 8601d8d032543665c9cb42128f993100 263 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 101 6.7E-9 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_35780 8601d8d032543665c9cb42128f993100 263 SUPERFAMILY SSF46946 127 192 1.55E-18 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFR_35780 8601d8d032543665c9cb42128f993100 263 SUPERFAMILY SSF57716 221 260 1.45E-11 T 12-10-2018 AFR_35780 8601d8d032543665c9cb42128f993100 263 Gene3D G3DSA:3.20.190.10 2 128 3.1E-25 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_35780 8601d8d032543665c9cb42128f993100 263 SMART SM01232 128 216 3.0E-19 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_35780 8601d8d032543665c9cb42128f993100 263 SUPERFAMILY SSF81624 2 137 2.88E-21 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_35780 8601d8d032543665c9cb42128f993100 263 Pfam PF06827 Zinc finger found in FPG and IleRS 233 260 2.4E-7 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFR_35780 8601d8d032543665c9cb42128f993100 263 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 128 191 1.1E-9 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_20240 5e6cc45cd1d95ba65435261facf98c15 212 SUPERFAMILY SSF52317 2 208 5.79E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_20240 5e6cc45cd1d95ba65435261facf98c15 212 Gene3D G3DSA:3.40.50.880 1 212 3.7E-70 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_20240 5e6cc45cd1d95ba65435261facf98c15 212 Pfam PF01965 DJ-1/PfpI family 29 208 1.6E-17 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_01095 5ebe8cfdb658f507533ca7f061eed77e 302 Gene3D G3DSA:1.10.510.10 181 257 1.0E-13 T 12-10-2018 AFR_01095 5ebe8cfdb658f507533ca7f061eed77e 302 SUPERFAMILY SSF56112 12 275 5.69E-22 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_01095 5ebe8cfdb658f507533ca7f061eed77e 302 Pfam PF01636 Phosphotransferase enzyme family 108 264 1.6E-13 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 PIRSF PIRSF016578 2 390 1.1E-25 T 12-10-2018 AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 Gene3D G3DSA:2.40.110.10 118 210 1.1E-25 T 12-10-2018 AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 SUPERFAMILY SSF47203 215 385 2.26E-23 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 115 1.2E-8 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 Gene3D G3DSA:1.10.540.10 9 116 1.2E-18 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 SUPERFAMILY SSF56645 14 210 3.8E-38 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 229 367 1.9E-18 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 Gene3D G3DSA:1.20.140.10 211 388 7.6E-48 T 12-10-2018 AFR_24540 4d83b9439d6189dffc7635bab13ab8b9 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 205 6.7E-10 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_10525 b8e10fe005111f8c85abf57b4bc40025 346 Gene3D G3DSA:3.40.50.300 92 262 2.3E-42 T 12-10-2018 AFR_10525 b8e10fe005111f8c85abf57b4bc40025 346 SUPERFAMILY SSF52540 107 323 3.94E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10525 b8e10fe005111f8c85abf57b4bc40025 346 Gene3D G3DSA:1.10.40.50 265 334 2.2E-20 T 12-10-2018 AFR_10525 b8e10fe005111f8c85abf57b4bc40025 346 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 69 318 3.6E-43 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 AFR_10525 b8e10fe005111f8c85abf57b4bc40025 346 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 26 326 29.582 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 AFR_10525 b8e10fe005111f8c85abf57b4bc40025 346 Pfam PF03193 RsgA GTPase 88 262 1.7E-40 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 AFR_20415 f9eb8776eaea3eaff6d47bbc7f6d33c6 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 4.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20415 f9eb8776eaea3eaff6d47bbc7f6d33c6 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 129 142 4.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20415 f9eb8776eaea3eaff6d47bbc7f6d33c6 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 86 4.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20415 f9eb8776eaea3eaff6d47bbc7f6d33c6 271 Pfam PF12697 Alpha/beta hydrolase family 50 258 5.9E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_20415 f9eb8776eaea3eaff6d47bbc7f6d33c6 271 SUPERFAMILY SSF53474 21 265 3.67E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20415 f9eb8776eaea3eaff6d47bbc7f6d33c6 271 Gene3D G3DSA:3.40.50.1820 21 266 9.9E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15265 b75b0f563177130acd8485c0efe0e41e 151 Pfam PF01475 Ferric uptake regulator family 13 121 2.3E-21 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFR_15265 b75b0f563177130acd8485c0efe0e41e 151 Gene3D G3DSA:3.30.1490.190 84 144 4.0E-12 T 12-10-2018 AFR_15265 b75b0f563177130acd8485c0efe0e41e 151 SUPERFAMILY SSF46785 4 133 4.3E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15265 b75b0f563177130acd8485c0efe0e41e 151 Gene3D G3DSA:1.10.10.10 1 82 6.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.171 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 SUPERFAMILY SSF143800 1 67 2.83E-24 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 Pfam PF01197 Ribosomal protein L31 1 66 4.2E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 4.3E-20 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 4.3E-20 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.3E-20 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 Gene3D G3DSA:2.30.170.50 1 70 1.1E-30 T 12-10-2018 AFR_37425 1f65f05119251251e1f76f8a41aa54d8 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 7.1E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_12870 2a208f02a3131f1c0a01ba77997b693c 565 SUPERFAMILY SSF52833 271 413 4.97E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_12870 2a208f02a3131f1c0a01ba77997b693c 565 Gene3D G3DSA:2.60.120.260 434 564 1.2E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_12870 2a208f02a3131f1c0a01ba77997b693c 565 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 208 6.0E-22 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFR_12870 2a208f02a3131f1c0a01ba77997b693c 565 Gene3D G3DSA:3.40.30.10 245 430 7.1E-48 T 12-10-2018 AFR_12870 2a208f02a3131f1c0a01ba77997b693c 565 Pfam PF00578 AhpC/TSA family 284 392 5.0E-11 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_19330 d1ba2c675f0e39015bc9599b99da92e6 551 Pfam PF08279 HTH domain 5 59 1.0E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_19330 d1ba2c675f0e39015bc9599b99da92e6 551 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFR_19330 d1ba2c675f0e39015bc9599b99da92e6 551 SUPERFAMILY SSF46785 2 60 6.43E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19330 d1ba2c675f0e39015bc9599b99da92e6 551 SMART SM00420 5 51 0.0029 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_19330 d1ba2c675f0e39015bc9599b99da92e6 551 Gene3D G3DSA:1.10.10.10 1 64 1.3E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19330 d1ba2c675f0e39015bc9599b99da92e6 551 Pfam PF13280 WYL domain 139 310 8.3E-24 T 12-10-2018 IPR026881 WYL domain AFR_29050 a766d71683544913a250e3f241c188bf 209 Pfam PF09335 SNARE associated Golgi protein 38 166 5.9E-25 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_06875 d634ab8b237fd3e48ce95bcbcc3049aa 245 PIRSF PIRSF006648 2 244 1.2E-44 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_06875 d634ab8b237fd3e48ce95bcbcc3049aa 245 Pfam PF01061 ABC-2 type transporter 8 209 7.2E-30 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_04785 32f9a768a5e3f4a8e720b73541a468cf 147 Gene3D G3DSA:3.90.1180.10 1 142 9.7E-62 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04785 32f9a768a5e3f4a8e720b73541a468cf 147 PIRSF PIRSF002181 2 147 1.0E-46 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFR_04785 32f9a768a5e3f4a8e720b73541a468cf 147 SUPERFAMILY SSF52161 4 144 4.32E-59 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFR_04785 32f9a768a5e3f4a8e720b73541a468cf 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 3.8E-59 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04785 32f9a768a5e3f4a8e720b73541a468cf 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 27.893 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFR_04785 32f9a768a5e3f4a8e720b73541a468cf 147 Pfam PF00572 Ribosomal protein L13 14 137 2.3E-56 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFR_24495 b3636876cf08ac86e91e096ac7a52409 272 Gene3D G3DSA:3.20.80.10 119 271 1.6E-16 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_24495 b3636876cf08ac86e91e096ac7a52409 272 Gene3D G3DSA:1.10.1660.10 3 118 6.9E-20 T 12-10-2018 AFR_24495 b3636876cf08ac86e91e096ac7a52409 272 SUPERFAMILY SSF46955 6 105 1.9E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_24495 b3636876cf08ac86e91e096ac7a52409 272 Pfam PF13411 MerR HTH family regulatory protein 7 74 9.3E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_24495 b3636876cf08ac86e91e096ac7a52409 272 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_24495 b3636876cf08ac86e91e096ac7a52409 272 SMART SM00422 6 76 4.4E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_38825 13528d9d95c21af158617b149782aaaa 340 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 103 8.4E-28 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_38825 13528d9d95c21af158617b149782aaaa 340 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 51 59 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_38825 13528d9d95c21af158617b149782aaaa 340 Gene3D G3DSA:1.10.1060.10 107 234 1.9E-14 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_38825 13528d9d95c21af158617b149782aaaa 340 Pfam PF13183 4Fe-4S dicluster domain 138 215 2.9E-15 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_38825 13528d9d95c21af158617b149782aaaa 340 SUPERFAMILY SSF46548 119 231 3.66E-17 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_38825 13528d9d95c21af158617b149782aaaa 340 SUPERFAMILY SSF54292 3 101 3.23E-23 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_38825 13528d9d95c21af158617b149782aaaa 340 Gene3D G3DSA:3.10.20.30 2 101 2.2E-28 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_38825 13528d9d95c21af158617b149782aaaa 340 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 15 222 1.2E-43 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFR_41915 35eea718a0108d4844e0ec16adc83f69 330 SUPERFAMILY SSF51735 2 169 3.59E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41915 35eea718a0108d4844e0ec16adc83f69 330 SUPERFAMILY SSF48179 183 288 6.57E-21 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_41915 35eea718a0108d4844e0ec16adc83f69 330 Gene3D G3DSA:3.40.50.720 1 185 1.8E-46 T 12-10-2018 AFR_41915 35eea718a0108d4844e0ec16adc83f69 330 Gene3D G3DSA:1.10.3660.10 186 287 2.9E-26 T 12-10-2018 AFR_41915 35eea718a0108d4844e0ec16adc83f69 330 Pfam PF02153 Prephenate dehydrogenase 67 262 5.9E-38 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 AFR_02840 efc67286d4bae07be5889db9d02438e5 158 SUPERFAMILY SSF88659 92 149 1.46E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_02840 efc67286d4bae07be5889db9d02438e5 158 SUPERFAMILY SSF88946 3 81 6.28E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02840 efc67286d4bae07be5889db9d02438e5 158 Gene3D G3DSA:1.10.10.10 75 151 8.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02840 efc67286d4bae07be5889db9d02438e5 158 Gene3D G3DSA:1.10.1740.10 1 74 4.6E-9 T 12-10-2018 AFR_02840 efc67286d4bae07be5889db9d02438e5 158 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 149 1.8E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02840 efc67286d4bae07be5889db9d02438e5 158 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 2 151 5.2E-49 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_02840 efc67286d4bae07be5889db9d02438e5 158 Pfam PF04542 Sigma-70 region 2 7 73 5.2E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02840 efc67286d4bae07be5889db9d02438e5 158 Pfam PF08281 Sigma-70, region 4 95 145 4.9E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_28210 d44621819f18e63c3eed502f687d6c14 599 SUPERFAMILY SSF49265 399 499 3.14E-15 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_28210 d44621819f18e63c3eed502f687d6c14 599 Gene3D G3DSA:2.130.10.10 76 346 3.9E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_28210 d44621819f18e63c3eed502f687d6c14 599 SUPERFAMILY SSF82171 14 422 9.81E-8 T 12-10-2018 AFR_28210 d44621819f18e63c3eed502f687d6c14 599 SMART SM00060 408 488 3.9E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_28210 d44621819f18e63c3eed502f687d6c14 599 Pfam PF00041 Fibronectin type III domain 411 489 1.8E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_28210 d44621819f18e63c3eed502f687d6c14 599 Gene3D G3DSA:2.60.40.10 395 499 8.6E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_40870 036f130b13dc45016b91200c7b35cce5 408 Gene3D G3DSA:1.20.1250.20 1 386 1.2E-26 T 12-10-2018 AFR_40870 036f130b13dc45016b91200c7b35cce5 408 SUPERFAMILY SSF103473 2 391 1.57E-35 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_40870 036f130b13dc45016b91200c7b35cce5 408 Pfam PF05977 Transmembrane secretion effector 1 394 6.1E-24 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_16425 1b27c2d7e523fd7a7962d1a46c980721 359 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 322 332 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_16425 1b27c2d7e523fd7a7962d1a46c980721 359 SUPERFAMILY SSF52743 133 351 2.75E-32 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_16425 1b27c2d7e523fd7a7962d1a46c980721 359 Gene3D G3DSA:3.40.50.200 128 357 4.0E-32 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_16425 1b27c2d7e523fd7a7962d1a46c980721 359 Pfam PF00082 Subtilase family 161 341 2.0E-14 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_16425 1b27c2d7e523fd7a7962d1a46c980721 359 PRINTS PR00723 Subtilisin serine protease family (S8) signature 321 337 9.4E-11 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_16425 1b27c2d7e523fd7a7962d1a46c980721 359 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 173 9.4E-11 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_16425 1b27c2d7e523fd7a7962d1a46c980721 359 PRINTS PR00723 Subtilisin serine protease family (S8) signature 138 157 9.4E-11 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 366 7.6E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 Gene3D G3DSA:1.10.287.130 102 224 1.7E-23 T 12-10-2018 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 SMART SM00304 98 156 2.8E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 Gene3D G3DSA:3.30.565.10 225 368 5.0E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 321 2.9E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 345 2.9E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 364 2.9E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 Pfam PF00672 HAMP domain 99 152 8.9E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 SMART SM00387 255 367 5.4E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 SMART SM00388 157 223 3.5E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 Pfam PF00512 His Kinase A (phospho-acceptor) domain 158 222 2.3E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 SUPERFAMILY SSF47384 140 221 3.14E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 SUPERFAMILY SSF158472 100 153 5.62E-6 T 12-10-2018 AFR_07205 64d718cf2aa78170c8d12ce355d89e93 370 SUPERFAMILY SSF55874 251 364 1.2E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_39080 d2436e723bebb6fe5e35875df4b4d112 448 SUPERFAMILY SSF103473 8 438 4.45E-43 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_39080 d2436e723bebb6fe5e35875df4b4d112 448 Pfam PF07690 Major Facilitator Superfamily 23 354 1.1E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_39080 d2436e723bebb6fe5e35875df4b4d112 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 1.4E-6 T 12-10-2018 AFR_39080 d2436e723bebb6fe5e35875df4b4d112 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 1.4E-6 T 12-10-2018 AFR_39080 d2436e723bebb6fe5e35875df4b4d112 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 398 417 1.4E-6 T 12-10-2018 AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 Pfam PF00989 PAS fold 462 569 3.0E-8 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 SUPERFAMILY SSF55785 454 570 3.49E-15 T 12-10-2018 IPR035965 PAS domain superfamily AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 579 745 1.3E-35 T 12-10-2018 IPR000160 GGDEF domain AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 SUPERFAMILY SSF141868 765 1013 2.09E-86 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 Gene3D G3DSA:3.30.450.20 458 581 3.5E-17 T 12-10-2018 AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 SMART SM00267 572 748 3.7E-51 T 12-10-2018 IPR000160 GGDEF domain AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 Gene3D G3DSA:3.20.20.450 761 1016 8.4E-97 T 12-10-2018 IPR035919 EAL domain superfamily AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 SMART SM00052 758 1006 1.3E-111 T 12-10-2018 IPR001633 EAL domain AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 SUPERFAMILY SSF55073 588 749 1.49E-38 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 456 579 2.8E-15 T 12-10-2018 IPR000014 PAS domain AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 Gene3D G3DSA:3.30.70.270 582 760 5.0E-48 T 12-10-2018 AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 Pfam PF00563 EAL domain 764 1001 2.8E-71 T 12-10-2018 IPR001633 EAL domain AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 Pfam PF00990 Diguanylate cyclase, GGDEF domain 583 743 1.6E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_17085 62e29b60ee1f14d9ee39aeef4d779cf6 1018 SMART SM00091 460 524 1.2E-6 T 12-10-2018 IPR000014 PAS domain AFR_05465 9a4bcee300e9ef6a98581dffad18105f 173 Gene3D G3DSA:3.40.630.30 5 166 5.0E-32 T 12-10-2018 AFR_05465 9a4bcee300e9ef6a98581dffad18105f 173 Pfam PF00583 Acetyltransferase (GNAT) family 48 140 2.6E-12 T 12-10-2018 IPR000182 GNAT domain AFR_05465 9a4bcee300e9ef6a98581dffad18105f 173 SUPERFAMILY SSF55729 1 157 5.14E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_07750 11d2a2b4df4df7e0df3fb789f4247169 262 Gene3D G3DSA:3.40.50.150 67 259 1.0E-39 T 12-10-2018 AFR_07750 11d2a2b4df4df7e0df3fb789f4247169 262 Gene3D G3DSA:1.10.8.10 6 66 1.4E-5 T 12-10-2018 AFR_07750 11d2a2b4df4df7e0df3fb789f4247169 262 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 33 231 4.7E-37 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AFR_07750 11d2a2b4df4df7e0df3fb789f4247169 262 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 10 250 2.2E-92 T 12-10-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase AFR_07750 11d2a2b4df4df7e0df3fb789f4247169 262 SUPERFAMILY SSF53335 45 216 1.22E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_07750 11d2a2b4df4df7e0df3fb789f4247169 262 Pfam PF05175 Methyltransferase small domain 65 167 1.6E-11 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFR_30865 050dddec7c1a87402d4c26905921f100 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 269 1.4E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30865 050dddec7c1a87402d4c26905921f100 279 SUPERFAMILY SSF161098 4 273 2.62E-66 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30865 050dddec7c1a87402d4c26905921f100 279 Gene3D G3DSA:1.10.3720.10 5 267 4.1E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_12700 6d82df8e0ee30cb8c6c0356465ff390e 423 Gene3D G3DSA:1.20.1250.20 232 417 1.6E-20 T 12-10-2018 AFR_12700 6d82df8e0ee30cb8c6c0356465ff390e 423 Pfam PF07690 Major Facilitator Superfamily 22 275 4.0E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_12700 6d82df8e0ee30cb8c6c0356465ff390e 423 SUPERFAMILY SSF103473 14 416 3.79E-49 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_12700 6d82df8e0ee30cb8c6c0356465ff390e 423 Gene3D G3DSA:1.20.1250.20 13 205 3.6E-20 T 12-10-2018 AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 Gene3D G3DSA:1.20.1290.10 128 214 8.6E-8 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 Pfam PF07883 Cupin domain 40 101 4.1E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 Pfam PF02627 Carboxymuconolactone decarboxylase family 253 325 1.7E-8 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 Pfam PF02627 Carboxymuconolactone decarboxylase family 134 196 1.6E-6 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 SUPERFAMILY SSF69118 125 335 1.9E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 Gene3D G3DSA:2.60.120.10 1 127 7.2E-48 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 Gene3D G3DSA:1.20.1290.10 230 340 8.5E-18 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_14515 7df75aefa44e339dcb9edd6452ad35eb 352 SUPERFAMILY SSF51182 11 132 2.89E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_30670 fb3ab8c1bcc135b28405925a3fc8e713 324 Pfam PF08279 HTH domain 7 62 1.1E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 AFR_30670 fb3ab8c1bcc135b28405925a3fc8e713 324 Gene3D G3DSA:1.10.10.10 6 65 4.2E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30670 fb3ab8c1bcc135b28405925a3fc8e713 324 Pfam PF13280 WYL domain 147 318 4.0E-37 T 12-10-2018 IPR026881 WYL domain AFR_30670 fb3ab8c1bcc135b28405925a3fc8e713 324 SUPERFAMILY SSF46785 5 64 3.27E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30670 fb3ab8c1bcc135b28405925a3fc8e713 324 PIRSF PIRSF016838 3 54 0.028 T 12-10-2018 IPR028349 Protein PafC AFR_30670 fb3ab8c1bcc135b28405925a3fc8e713 324 PIRSF PIRSF016838 69 324 6.4E-24 T 12-10-2018 IPR028349 Protein PafC AFR_13335 7cc066f88f3f5400ad46c690842d5fd4 387 Pfam PF02687 FtsX-like permease family 293 381 8.6E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_13335 7cc066f88f3f5400ad46c690842d5fd4 387 Pfam PF12704 MacB-like periplasmic core domain 24 229 2.7E-18 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 SUPERFAMILY SSF52540 12 158 2.06E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 SUPERFAMILY SSF48452 371 762 9.49E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 Gene3D G3DSA:1.10.10.10 813 882 7.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 825 839 3.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 839 855 3.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 855 867 3.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 Pfam PF13191 AAA ATPase domain 3 152 1.2E-21 T 12-10-2018 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 SMART SM00421 822 879 5.8E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 ProSitePatterns PS00622 LuxR-type HTH domain signature. 839 866 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 SUPERFAMILY SSF46894 818 880 7.48E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 Pfam PF00196 Bacterial regulatory proteins, luxR family 825 878 7.1E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_31895 7a241d78eb5563ab44c89593c03eceab 885 Gene3D G3DSA:3.40.50.300 3 159 4.8E-5 T 12-10-2018 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 Pfam PF00248 Aldo/keto reductase family 23 261 1.0E-40 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 PRINTS PR00069 Aldo-keto reductase signature 42 66 2.2E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 PRINTS PR00069 Aldo-keto reductase signature 197 221 2.2E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 PRINTS PR00069 Aldo-keto reductase signature 127 144 2.2E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 PRINTS PR00069 Aldo-keto reductase signature 96 114 2.2E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 PRINTS PR00069 Aldo-keto reductase signature 161 190 2.2E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 Gene3D G3DSA:3.20.20.100 2 265 3.8E-93 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 SUPERFAMILY SSF51430 18 261 7.2E-78 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 46 63 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 PIRSF PIRSF000097 116 265 3.8E-35 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 PIRSF PIRSF000097 6 121 5.5E-35 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_27020 0101e4218c0694a26e34d79ee5e3155f 265 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFR_07145 b54cdab8f439badcb4a13bf69b5bb683 209 SUPERFAMILY SSF53335 38 183 8.05E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_07145 b54cdab8f439badcb4a13bf69b5bb683 209 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 64 133 1.4E-12 T 12-10-2018 AFR_07145 b54cdab8f439badcb4a13bf69b5bb683 209 Gene3D G3DSA:3.40.50.150 32 184 1.5E-21 T 12-10-2018 AFR_06725 efbcb65d43c06b0eb29cfa2b5f8f5444 213 Gene3D G3DSA:3.40.50.300 3 212 8.6E-46 T 12-10-2018 AFR_06725 efbcb65d43c06b0eb29cfa2b5f8f5444 213 SMART SM00382 34 207 1.0E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_06725 efbcb65d43c06b0eb29cfa2b5f8f5444 213 SUPERFAMILY SSF52540 4 210 1.0E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06725 efbcb65d43c06b0eb29cfa2b5f8f5444 213 Pfam PF00005 ABC transporter 25 161 7.5E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 SUPERFAMILY SSF46785 14 81 2.19E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 Pfam PF07729 FCD domain 91 205 4.3E-16 T 12-10-2018 IPR011711 GntR, C-terminal AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 SUPERFAMILY SSF48008 85 205 2.14E-14 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 SMART SM00895 87 209 3.2E-6 T 12-10-2018 IPR011711 GntR, C-terminal AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 Gene3D G3DSA:1.20.120.530 85 211 4.9E-16 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 Gene3D G3DSA:1.10.10.10 11 78 4.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 SMART SM00345 19 77 2.0E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_14150 26593ac6f4a017ccedfc75d7b1d7367c 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 1.2E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_34680 fd616391bb1d6652fb7e49ed6e88881a 687 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 162 592 1.5E-58 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFR_34680 fd616391bb1d6652fb7e49ed6e88881a 687 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 61 674 5.8E-118 T 12-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ AFR_39545 f635e3982b4698e53c628b684b75b13d 1224 Gene3D G3DSA:3.30.565.10 508 662 3.9E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_39545 f635e3982b4698e53c628b684b75b13d 1224 Pfam PF00672 HAMP domain 357 430 9.5E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_39545 f635e3982b4698e53c628b684b75b13d 1224 SUPERFAMILY SSF55874 546 656 4.06E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_39545 f635e3982b4698e53c628b684b75b13d 1224 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 552 655 2.1E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_39545 f635e3982b4698e53c628b684b75b13d 1224 SMART SM00387 547 658 1.1E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_39545 f635e3982b4698e53c628b684b75b13d 1224 SMART SM00304 357 434 4.2E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_39545 f635e3982b4698e53c628b684b75b13d 1224 Pfam PF08376 Nitrate and nitrite sensing 76 319 1.7E-33 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein AFR_12020 88577b96ec359e5590b8a39b5faaf79c 302 SMART SM00283 86 296 2.2E-10 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_12020 88577b96ec359e5590b8a39b5faaf79c 302 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 181 208 1.2E-17 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_12020 88577b96ec359e5590b8a39b5faaf79c 302 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 210 239 1.2E-17 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_12020 88577b96ec359e5590b8a39b5faaf79c 302 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 103 132 1.2E-17 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_12020 88577b96ec359e5590b8a39b5faaf79c 302 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 140 267 4.4E-28 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_12020 88577b96ec359e5590b8a39b5faaf79c 302 SUPERFAMILY SSF58104 46 272 3.01E-41 T 12-10-2018 AFR_12020 88577b96ec359e5590b8a39b5faaf79c 302 Gene3D G3DSA:1.10.287.950 11 300 1.7E-40 T 12-10-2018 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 SMART SM00388 368 432 4.5E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 2.0E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 2.0E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 2.0E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 2.0E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 SUPERFAMILY SSF158472 319 361 2.75E-5 T 12-10-2018 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 SMART SM00304 318 367 0.0014 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 SUPERFAMILY SSF55874 421 585 1.7E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13325 e846d6f81481dd17de1b103e7441c718 595 Gene3D G3DSA:3.30.565.10 433 590 3.9E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13325 e846d6f81481dd17de1b103e7441c718 595 Pfam PF00672 HAMP domain 319 361 3.8E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 Gene3D G3DSA:1.10.287.130 374 432 3.3E-11 T 12-10-2018 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 SMART SM00387 477 589 1.3E-40 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13325 e846d6f81481dd17de1b103e7441c718 595 Pfam PF00512 His Kinase A (phospho-acceptor) domain 369 432 4.2E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 586 3.6E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_13325 e846d6f81481dd17de1b103e7441c718 595 SUPERFAMILY SSF47384 351 433 1.33E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_13325 e846d6f81481dd17de1b103e7441c718 595 Gene3D G3DSA:1.20.1480.50 291 373 4.5E-7 T 12-10-2018 AFR_20390 75fe9ca5c9a6eb8eb65ac4f659b46461 369 Gene3D G3DSA:3.20.20.150 58 363 1.1E-56 T 12-10-2018 AFR_20390 75fe9ca5c9a6eb8eb65ac4f659b46461 369 SUPERFAMILY SSF51658 84 342 3.18E-27 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_20390 75fe9ca5c9a6eb8eb65ac4f659b46461 369 Pfam PF01261 Xylose isomerase-like TIM barrel 93 316 1.2E-26 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_17830 aa4966ac05dab1ee350b45f735c1d654 257 SUPERFAMILY SSF52833 47 151 3.98E-6 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_17830 aa4966ac05dab1ee350b45f735c1d654 257 Pfam PF05988 Bacterial protein of unknown function (DUF899) 2 229 9.1E-84 T 12-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like AFR_41550 d61f4968399aa60441e7c0d526a620f1 307 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 296 20.208 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFR_41550 d61f4968399aa60441e7c0d526a620f1 307 Pfam PF01171 PP-loop family 11 186 2.5E-39 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFR_41550 d61f4968399aa60441e7c0d526a620f1 307 SUPERFAMILY SSF52402 4 219 1.6E-48 T 12-10-2018 AFR_41550 d61f4968399aa60441e7c0d526a620f1 307 SUPERFAMILY SSF82829 198 301 5.49E-16 T 12-10-2018 AFR_41550 d61f4968399aa60441e7c0d526a620f1 307 Pfam PF09179 TilS substrate binding domain 235 302 5.4E-11 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFR_41550 d61f4968399aa60441e7c0d526a620f1 307 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 11 190 6.9E-43 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFR_41550 d61f4968399aa60441e7c0d526a620f1 307 Gene3D G3DSA:3.40.50.620 2 220 1.0E-63 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_05615 9d4378f299d18c4e89f0dc2d1ec48ced 171 Pfam PF03061 Thioesterase superfamily 29 100 5.3E-17 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFR_05615 9d4378f299d18c4e89f0dc2d1ec48ced 171 SUPERFAMILY SSF54637 11 160 4.6E-43 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_05615 9d4378f299d18c4e89f0dc2d1ec48ced 171 Gene3D G3DSA:3.10.129.10 3 167 1.1E-51 T 12-10-2018 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 Pfam PF13353 4Fe-4S single cluster domain 18 106 9.5E-7 T 12-10-2018 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 Pfam PF04055 Radical SAM superfamily 16 177 1.5E-29 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 333 4.0E-107 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 Gene3D G3DSA:3.20.20.70 1 333 3.9E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 315 2.2E-31 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 SMART SM00729 11 207 2.1E-4 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 2 333 38.887 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42665 e5a02f9d9ec4427e7a7cb38c00de4b9c 333 SUPERFAMILY SSF102114 4 281 7.72E-67 T 12-10-2018 AFR_42660 2f61722636b5f1375f8f0237256dcbf8 293 SUPERFAMILY SSF56112 23 279 6.69E-40 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_42660 2f61722636b5f1375f8f0237256dcbf8 293 PIRSF PIRSF006221 10 293 1.1E-57 T 12-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 AFR_42660 2f61722636b5f1375f8f0237256dcbf8 293 Pfam PF03881 Fructosamine kinase 23 286 1.2E-45 T 12-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 AFR_42660 2f61722636b5f1375f8f0237256dcbf8 293 Gene3D G3DSA:1.20.1270.240 126 279 1.1E-62 T 12-10-2018 AFR_42660 2f61722636b5f1375f8f0237256dcbf8 293 Gene3D G3DSA:3.30.200.20 11 94 1.3E-24 T 12-10-2018 AFR_42660 2f61722636b5f1375f8f0237256dcbf8 293 Gene3D G3DSA:1.10.510.10 104 255 1.1E-62 T 12-10-2018 AFR_10260 69f9802390fa86883a39507282443c00 246 SUPERFAMILY SSF50475 79 235 2.75E-15 T 12-10-2018 AFR_10260 69f9802390fa86883a39507282443c00 246 Pfam PF10615 Protein of unknown function (DUF2470) 164 229 8.2E-5 T 12-10-2018 IPR019595 Domain of unknown function DUF2470 AFR_10260 69f9802390fa86883a39507282443c00 246 Gene3D G3DSA:3.20.180.10 150 235 3.3E-7 T 12-10-2018 IPR037119 Haem oxygenase HugZ-like superfamily AFR_14415 a63c67b0be1fb9b61af3b7a98fee4a93 287 SUPERFAMILY SSF51679 9 268 4.56E-36 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_14415 a63c67b0be1fb9b61af3b7a98fee4a93 287 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 8 285 1.7E-96 T 12-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted AFR_14415 a63c67b0be1fb9b61af3b7a98fee4a93 287 Gene3D G3DSA:3.20.20.30 135 285 7.2E-10 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_14415 a63c67b0be1fb9b61af3b7a98fee4a93 287 Gene3D G3DSA:3.20.20.30 12 134 1.7E-12 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_14415 a63c67b0be1fb9b61af3b7a98fee4a93 287 Pfam PF00296 Luciferase-like monooxygenase 17 128 1.2E-13 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_14415 a63c67b0be1fb9b61af3b7a98fee4a93 287 Pfam PF00296 Luciferase-like monooxygenase 139 259 5.8E-5 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_11755 e936cf252b8fbef377919b48653cb7e6 178 Gene3D G3DSA:3.40.630.30 7 172 7.4E-35 T 12-10-2018 AFR_11755 e936cf252b8fbef377919b48653cb7e6 178 Pfam PF13302 Acetyltransferase (GNAT) domain 17 157 1.2E-21 T 12-10-2018 IPR000182 GNAT domain AFR_11755 e936cf252b8fbef377919b48653cb7e6 178 SUPERFAMILY SSF55729 11 162 1.77E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_33975 3d55aafca02a3089aab156c79164f5e6 1182 Pfam PF02514 CobN/Magnesium Chelatase 99 1162 0.0 T 12-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 AFR_33975 3d55aafca02a3089aab156c79164f5e6 1182 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 40 1175 0.0 T 12-10-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 AFR_10275 32675f38838ab04ab78a677e0cb7c12b 241 SMART SM00382 29 212 4.8E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10275 32675f38838ab04ab78a677e0cb7c12b 241 Pfam PF00005 ABC transporter 20 157 4.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10275 32675f38838ab04ab78a677e0cb7c12b 241 SUPERFAMILY SSF52540 4 218 6.88E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10275 32675f38838ab04ab78a677e0cb7c12b 241 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10275 32675f38838ab04ab78a677e0cb7c12b 241 Gene3D G3DSA:3.40.50.300 1 237 5.4E-60 T 12-10-2018 AFR_20250 22c92665a4077795072ad0f2690cd0ff 201 SMART SM00866 47 183 1.5E-24 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_20250 22c92665a4077795072ad0f2690cd0ff 201 Gene3D G3DSA:1.10.10.10 1 25 2.2E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20250 22c92665a4077795072ad0f2690cd0ff 201 Pfam PF07702 UTRA domain 47 177 7.7E-25 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFR_20250 22c92665a4077795072ad0f2690cd0ff 201 SUPERFAMILY SSF64288 14 186 2.83E-38 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_20250 22c92665a4077795072ad0f2690cd0ff 201 Gene3D G3DSA:3.40.1410.10 26 176 3.8E-34 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFR_20250 22c92665a4077795072ad0f2690cd0ff 201 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 26 1.5E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_36555 077a58c90480f49ddba47a0e451e43ba 191 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFR_36555 077a58c90480f49ddba47a0e451e43ba 191 PIRSF PIRSF004553 1 191 4.6E-50 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFR_36555 077a58c90480f49ddba47a0e451e43ba 191 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 188 4.5E-44 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFR_36555 077a58c90480f49ddba47a0e451e43ba 191 Pfam PF03602 Conserved hypothetical protein 95 2 187 2.3E-49 T 12-10-2018 AFR_36555 077a58c90480f49ddba47a0e451e43ba 191 SUPERFAMILY SSF53335 3 187 1.03E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_36555 077a58c90480f49ddba47a0e451e43ba 191 Gene3D G3DSA:3.40.50.150 1 191 9.2E-53 T 12-10-2018 AFR_29150 9f4e8d1a815ee72a176d8ab6bbe422b4 225 SUPERFAMILY SSF51735 3 199 3.66E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29150 9f4e8d1a815ee72a176d8ab6bbe422b4 225 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 92 5.7E-18 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_29150 9f4e8d1a815ee72a176d8ab6bbe422b4 225 Gene3D G3DSA:3.40.50.720 1 196 1.0E-48 T 12-10-2018 AFR_10775 4ab4e9847b098df352e6e3b80d640ba9 306 Pfam PF04228 Putative neutral zinc metallopeptidase 8 300 2.2E-86 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative AFR_07190 5803cbeac3932fea5d59e164b756d36e 402 Pfam PF01494 FAD binding domain 7 347 2.1E-26 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_07190 5803cbeac3932fea5d59e164b756d36e 402 SUPERFAMILY SSF51905 7 375 8.24E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_07190 5803cbeac3932fea5d59e164b756d36e 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 2.3E-20 T 12-10-2018 AFR_07190 5803cbeac3932fea5d59e164b756d36e 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 2.3E-20 T 12-10-2018 AFR_07190 5803cbeac3932fea5d59e164b756d36e 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 2.3E-20 T 12-10-2018 AFR_07190 5803cbeac3932fea5d59e164b756d36e 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.3E-20 T 12-10-2018 AFR_07190 5803cbeac3932fea5d59e164b756d36e 402 Gene3D G3DSA:3.50.50.60 7 358 6.2E-77 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_28085 01610cfadcf7e426a8196f2b7b2d1a8d 61 Gene3D G3DSA:1.10.10.10 1 48 1.7E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28085 01610cfadcf7e426a8196f2b7b2d1a8d 61 SUPERFAMILY SSF46785 1 46 8.34E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00690 Adhesin family signature 183 204 1.7E-27 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00690 Adhesin family signature 67 80 1.7E-27 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00690 Adhesin family signature 36 54 1.7E-27 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00690 Adhesin family signature 80 97 1.7E-27 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00690 Adhesin family signature 267 286 1.7E-27 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00690 Adhesin family signature 238 256 1.7E-27 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 299 2.4E-74 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 Gene3D G3DSA:3.40.50.1980 35 175 1.5E-44 T 12-10-2018 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 SUPERFAMILY SSF53807 35 302 5.89E-76 T 12-10-2018 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00691 Adhesin B signature 80 99 1.3E-11 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00691 Adhesin B signature 61 79 1.3E-11 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00691 Adhesin B signature 234 251 1.3E-11 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 PRINTS PR00691 Adhesin B signature 36 57 1.3E-11 T 12-10-2018 IPR006129 Adhesin B GO:0007155 AFR_18795 4cff2444c774a07f151427d36d939bf4 303 Gene3D G3DSA:3.40.50.1980 176 303 7.7E-36 T 12-10-2018 AFR_13460 0f5c619a3ba888dc33ef64a8aedd0ffd 396 Pfam PF07690 Major Facilitator Superfamily 20 353 1.5E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_13460 0f5c619a3ba888dc33ef64a8aedd0ffd 396 Gene3D G3DSA:1.20.1250.20 207 390 6.4E-17 T 12-10-2018 AFR_13460 0f5c619a3ba888dc33ef64a8aedd0ffd 396 Gene3D G3DSA:1.20.1250.20 10 198 2.2E-16 T 12-10-2018 AFR_13460 0f5c619a3ba888dc33ef64a8aedd0ffd 396 SUPERFAMILY SSF103473 9 389 6.41E-46 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_30160 6118216cf14a78e8380fb9e60b4e837a 252 SUPERFAMILY SSF56300 3 194 8.05E-21 T 12-10-2018 AFR_30160 6118216cf14a78e8380fb9e60b4e837a 252 Pfam PF00149 Calcineurin-like phosphoesterase 3 190 1.6E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_30160 6118216cf14a78e8380fb9e60b4e837a 252 Gene3D G3DSA:3.60.21.10 1 203 3.9E-21 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_34980 043065fe610bea471ea169c41a55d3be 768 SUPERFAMILY SSF74650 5 252 7.22E-50 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_34980 043065fe610bea471ea169c41a55d3be 768 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 310 679 7.8E-123 T 12-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 AFR_34980 043065fe610bea471ea169c41a55d3be 768 SUPERFAMILY SSF48208 259 719 2.38E-113 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_34980 043065fe610bea471ea169c41a55d3be 768 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 683 732 1.1E-14 T 12-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal AFR_34980 043065fe610bea471ea169c41a55d3be 768 Gene3D G3DSA:1.50.10.10 304 664 5.0E-115 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_34980 043065fe610bea471ea169c41a55d3be 768 Gene3D G3DSA:2.60.420.10 665 735 2.0E-21 T 12-10-2018 AFR_34980 043065fe610bea471ea169c41a55d3be 768 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 18 252 4.9E-52 T 12-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 AFR_34980 043065fe610bea471ea169c41a55d3be 768 Gene3D G3DSA:2.70.98.40 1 255 3.7E-49 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily AFR_34980 043065fe610bea471ea169c41a55d3be 768 PIRSF PIRSF036289 3 744 1.7E-188 T 12-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase AFR_00420 37d04b589f1bc5a26c8f70ef8a43b229 375 SUPERFAMILY SSF81606 209 314 1.7E-7 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_00420 37d04b589f1bc5a26c8f70ef8a43b229 375 SMART SM00331 143 354 1.3E-23 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_00420 37d04b589f1bc5a26c8f70ef8a43b229 375 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 174 353 4.2E-34 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_00420 37d04b589f1bc5a26c8f70ef8a43b229 375 Gene3D G3DSA:3.60.40.10 147 357 1.0E-43 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_20495 a45b0505dcbb062d2051027719c0e094 121 SUPERFAMILY SSF54593 6 118 4.81E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_20495 a45b0505dcbb062d2051027719c0e094 121 Gene3D G3DSA:3.10.180.10 1 121 5.5E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 4.5E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 4.5E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 4.5E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 Gene3D G3DSA:3.40.50.1820 5 301 1.1E-83 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 SUPERFAMILY SSF53474 7 300 1.09E-73 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 Pfam PF00561 alpha/beta hydrolase fold 28 286 4.6E-27 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00412 Epoxide hydrolase signature 54 69 3.1E-26 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00412 Epoxide hydrolase signature 275 297 3.1E-26 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00412 Epoxide hydrolase signature 34 52 3.1E-26 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00412 Epoxide hydrolase signature 100 113 3.1E-26 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_19325 fb5438fcae10ac750ef8dcdde35416fb 301 PRINTS PR00412 Epoxide hydrolase signature 114 127 3.1E-26 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 SMART SM00448 4 126 4.7E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 SUPERFAMILY SSF52172 3 137 9.82E-25 T 12-10-2018 IPR011006 CheY-like superfamily AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 Gene3D G3DSA:3.50.50.60 229 548 6.0E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 Gene3D G3DSA:3.40.50.2300 2 145 7.5E-25 T 12-10-2018 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 Pfam PF00072 Response regulator receiver domain 6 119 1.2E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 367 391 4.7E-32 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 282 292 4.7E-32 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 512 530 4.7E-32 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 276 4.7E-32 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 329 337 4.7E-32 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 228 250 4.7E-32 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 SUPERFAMILY SSF51905 221 549 8.03E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 227 538 4.0E-29 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 371 389 8.3E-21 T 12-10-2018 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 457 473 8.3E-21 T 12-10-2018 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 248 8.3E-21 T 12-10-2018 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 328 346 8.3E-21 T 12-10-2018 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 502 524 8.3E-21 T 12-10-2018 AFR_33225 6083ed1aff6207e3cfb98016a0f56e5b 552 Gene3D G3DSA:3.50.50.60 340 465 6.0E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_26245 146beaa14b56f43785fbfae1528fe98b 421 Gene3D G3DSA:3.40.50.410 31 219 4.0E-120 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_26245 146beaa14b56f43785fbfae1528fe98b 421 SUPERFAMILY SSF53300 43 216 1.91E-23 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_26245 146beaa14b56f43785fbfae1528fe98b 421 Pfam PF13768 von Willebrand factor type A domain 43 197 3.8E-14 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_26245 146beaa14b56f43785fbfae1528fe98b 421 SMART SM00327 39 214 1.2E-8 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_26245 146beaa14b56f43785fbfae1528fe98b 421 Gene3D G3DSA:1.20.120.1690 317 420 1.2E-40 T 12-10-2018 AFR_26245 146beaa14b56f43785fbfae1528fe98b 421 Gene3D G3DSA:2.60.40.3670 4 315 4.0E-120 T 12-10-2018 AFR_36925 0c05c254fab66828cabdaa9c06d9afc6 427 Pfam PF01547 Bacterial extracellular solute-binding protein 56 334 2.2E-25 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_36925 0c05c254fab66828cabdaa9c06d9afc6 427 SUPERFAMILY SSF53850 40 423 1.09E-47 T 12-10-2018 AFR_36925 0c05c254fab66828cabdaa9c06d9afc6 427 Gene3D G3DSA:3.40.190.10 59 354 6.7E-63 T 12-10-2018 AFR_36925 0c05c254fab66828cabdaa9c06d9afc6 427 Gene3D G3DSA:3.40.190.10 153 414 6.7E-63 T 12-10-2018 AFR_39585 ee33469963970fff663f154c59ba00d8 515 SMART SM00382 12 208 2.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_39585 ee33469963970fff663f154c59ba00d8 515 SMART SM00382 264 468 2.4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_39585 ee33469963970fff663f154c59ba00d8 515 Gene3D G3DSA:3.40.50.300 1 218 1.9E-53 T 12-10-2018 AFR_39585 ee33469963970fff663f154c59ba00d8 515 Pfam PF00005 ABC transporter 256 411 8.4E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_39585 ee33469963970fff663f154c59ba00d8 515 SUPERFAMILY SSF52540 240 472 3.71E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39585 ee33469963970fff663f154c59ba00d8 515 ProSitePatterns PS00211 ABC transporters family signature. 384 398 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_39585 ee33469963970fff663f154c59ba00d8 515 Gene3D G3DSA:3.40.50.300 237 486 8.0E-39 T 12-10-2018 AFR_39585 ee33469963970fff663f154c59ba00d8 515 Pfam PF00005 ABC transporter 4 152 6.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_39585 ee33469963970fff663f154c59ba00d8 515 SUPERFAMILY SSF52540 2 209 2.0E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39325 d84ec92efa32987f34a43e0a5f6d1043 524 Pfam PF01039 Carboxyl transferase domain 36 522 3.3E-196 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFR_39325 d84ec92efa32987f34a43e0a5f6d1043 524 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 103 117 3.9E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFR_39325 d84ec92efa32987f34a43e0a5f6d1043 524 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 137 155 3.9E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFR_39325 d84ec92efa32987f34a43e0a5f6d1043 524 Gene3D G3DSA:3.90.226.10 1 266 8.4E-97 T 12-10-2018 AFR_39325 d84ec92efa32987f34a43e0a5f6d1043 524 SUPERFAMILY SSF52096 251 524 1.99E-88 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_39325 d84ec92efa32987f34a43e0a5f6d1043 524 SUPERFAMILY SSF52096 13 262 4.81E-79 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_39325 d84ec92efa32987f34a43e0a5f6d1043 524 Gene3D G3DSA:3.90.226.10 268 524 7.6E-90 T 12-10-2018 AFR_38880 000632bdeee2abe94c52a8038dcdae74 422 Gene3D G3DSA:3.40.50.2300 160 296 2.7E-76 T 12-10-2018 AFR_38880 000632bdeee2abe94c52a8038dcdae74 422 Gene3D G3DSA:3.40.50.2300 49 353 2.7E-76 T 12-10-2018 AFR_38880 000632bdeee2abe94c52a8038dcdae74 422 Pfam PF13458 Periplasmic binding protein 41 386 3.4E-59 T 12-10-2018 IPR028081 Leucine-binding protein domain AFR_38880 000632bdeee2abe94c52a8038dcdae74 422 SUPERFAMILY SSF53822 40 389 1.24E-62 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_02745 d72552413feb563d47721c3643649ed2 309 Gene3D G3DSA:3.90.180.10 8 302 1.8E-77 T 12-10-2018 AFR_02745 d72552413feb563d47721c3643649ed2 309 SUPERFAMILY SSF51735 113 275 4.06E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_02745 d72552413feb563d47721c3643649ed2 309 SUPERFAMILY SSF50129 1 141 1.67E-33 T 12-10-2018 IPR011032 GroES-like superfamily AFR_02745 d72552413feb563d47721c3643649ed2 309 Pfam PF13602 Zinc-binding dehydrogenase 184 303 4.2E-17 T 12-10-2018 AFR_02745 d72552413feb563d47721c3643649ed2 309 SMART SM00829 10 303 5.3E-14 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_02745 d72552413feb563d47721c3643649ed2 309 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFR_02745 d72552413feb563d47721c3643649ed2 309 Gene3D G3DSA:3.40.50.720 124 254 1.8E-77 T 12-10-2018 AFR_32045 2ddc182eb0dcb5695edf0e70eae8d861 211 SUPERFAMILY SSF55073 11 196 3.14E-35 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_32045 2ddc182eb0dcb5695edf0e70eae8d861 211 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 12 192 2.4E-19 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AFR_32045 2ddc182eb0dcb5695edf0e70eae8d861 211 Gene3D G3DSA:3.30.70.1230 9 204 1.3E-39 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_32045 2ddc182eb0dcb5695edf0e70eae8d861 211 SMART SM00044 1 179 0.0011 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AFR_40320 d3310c538dc03027db1650bc573f07ba 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.5E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40320 d3310c538dc03027db1650bc573f07ba 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.5E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40320 d3310c538dc03027db1650bc573f07ba 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.5E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40320 d3310c538dc03027db1650bc573f07ba 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.5E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40320 d3310c538dc03027db1650bc573f07ba 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.5E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40320 d3310c538dc03027db1650bc573f07ba 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.5E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40320 d3310c538dc03027db1650bc573f07ba 252 Pfam PF00106 short chain dehydrogenase 5 187 8.0E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_40320 d3310c538dc03027db1650bc573f07ba 252 Gene3D G3DSA:3.40.50.720 6 239 1.0E-62 T 12-10-2018 AFR_40320 d3310c538dc03027db1650bc573f07ba 252 SUPERFAMILY SSF51735 3 237 4.68E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_04825 266087c013467fcfa993596d5d0ffb23 122 SUPERFAMILY SSF56214 2 121 1.06E-27 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_04825 266087c013467fcfa993596d5d0ffb23 122 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 121 2.3E-25 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFR_04825 266087c013467fcfa993596d5d0ffb23 122 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 101 2.0E-16 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_04825 266087c013467fcfa993596d5d0ffb23 122 Gene3D G3DSA:3.90.470.20 1 122 5.5E-36 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_04825 266087c013467fcfa993596d5d0ffb23 122 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 21.671 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFR_04825 266087c013467fcfa993596d5d0ffb23 122 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 13 121 2.0E-12 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFR_04825 266087c013467fcfa993596d5d0ffb23 122 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 121 1.8E-17 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 Gene3D G3DSA:2.40.50.140 287 343 1.2E-21 T 12-10-2018 AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 SUPERFAMILY SSF50331 239 359 7.29E-21 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 Gene3D G3DSA:3.40.50.300 4 223 3.2E-67 T 12-10-2018 AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 Pfam PF00005 ABC transporter 22 163 3.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 Pfam PF03459 TOBE domain 300 342 2.2E-5 T 12-10-2018 IPR005116 Transport-associated OB, type 1 AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 SUPERFAMILY SSF52540 5 245 8.25E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 SMART SM00382 30 213 3.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 Gene3D G3DSA:2.40.50.940 224 352 1.2E-21 T 12-10-2018 AFR_18215 cb0bb03c6a94f27eac98c7ccf2780d45 362 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07405 0f18923448b901bc60ec6eab7219a7a7 152 Pfam PF10722 Putative bacterial sensory transduction regulator 20 146 6.2E-17 T 12-10-2018 IPR019660 Putative sensory transduction regulator YbjN AFR_25465 03947269b2b1ff64b53845b149f28ca8 260 Pfam PF00005 ABC transporter 21 173 1.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_25465 03947269b2b1ff64b53845b149f28ca8 260 Gene3D G3DSA:3.40.50.300 1 243 2.3E-54 T 12-10-2018 AFR_25465 03947269b2b1ff64b53845b149f28ca8 260 SMART SM00382 30 230 7.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25465 03947269b2b1ff64b53845b149f28ca8 260 SUPERFAMILY SSF52540 4 233 1.31E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 SUPERFAMILY SSF52096 19 190 1.53E-63 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 PRINTS PR00127 Clp protease catalytic subunit P signature 110 129 2.2E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 PRINTS PR00127 Clp protease catalytic subunit P signature 18 33 2.2E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 PRINTS PR00127 Clp protease catalytic subunit P signature 89 106 2.2E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 PRINTS PR00127 Clp protease catalytic subunit P signature 167 186 2.2E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 PRINTS PR00127 Clp protease catalytic subunit P signature 58 78 2.2E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 Pfam PF00574 Clp protease 17 191 4.6E-74 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 2 192 38.355 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFR_37860 d89bbecb9fe8b54e8e2a7ec1ddd5880a 202 Gene3D G3DSA:3.90.226.10 3 196 2.1E-71 T 12-10-2018 AFR_25985 82bf2c1eefb34c79ce7b56b3ca0e21ab 266 Pfam PF04909 Amidohydrolase 13 266 5.9E-20 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_25985 82bf2c1eefb34c79ce7b56b3ca0e21ab 266 SUPERFAMILY SSF51556 3 266 1.17E-31 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_25985 82bf2c1eefb34c79ce7b56b3ca0e21ab 266 Gene3D G3DSA:3.20.20.140 21 266 6.8E-35 T 12-10-2018 AFR_09030 51742e617f526a81db3121d3207b0cf9 149 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 132 2.9E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_09030 51742e617f526a81db3121d3207b0cf9 149 SUPERFAMILY SSF54593 6 141 1.29E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_09030 51742e617f526a81db3121d3207b0cf9 149 Gene3D G3DSA:3.10.180.10 4 149 3.7E-41 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 SUPERFAMILY SSF56784 3 209 3.64E-48 T 12-10-2018 IPR036412 HAD-like superfamily AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 184 6.8E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 Gene3D G3DSA:3.40.50.1000 6 186 1.7E-47 T 12-10-2018 IPR023214 HAD superfamily AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 Gene3D G3DSA:1.10.150.240 16 85 1.7E-47 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 9.5E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 9.5E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 9.5E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31785 49b1c1c96e8df115e225bfe34906c12b 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 184 1.8E-24 T 12-10-2018 AFR_08715 b88d23002239387e4b1776ea082c3a69 187 Gene3D G3DSA:1.10.357.10 69 184 5.3E-16 T 12-10-2018 AFR_08715 b88d23002239387e4b1776ea082c3a69 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 52 5.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_08715 b88d23002239387e4b1776ea082c3a69 187 SUPERFAMILY SSF46689 3 61 6.16E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_08715 b88d23002239387e4b1776ea082c3a69 187 SUPERFAMILY SSF48498 74 176 1.19E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_08715 b88d23002239387e4b1776ea082c3a69 187 Gene3D G3DSA:1.10.10.60 3 62 2.8E-17 T 12-10-2018 AFR_08715 b88d23002239387e4b1776ea082c3a69 187 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 162 5.9E-8 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_08715 b88d23002239387e4b1776ea082c3a69 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 2.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_08715 b88d23002239387e4b1776ea082c3a69 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 2.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15290 07d4517a2fc3ca73b877c249d141861c 333 SUPERFAMILY SSF51445 30 300 1.02E-36 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_15290 07d4517a2fc3ca73b877c249d141861c 333 Pfam PF02156 Glycosyl hydrolase family 26 32 328 3.2E-48 T 12-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 AFR_15290 07d4517a2fc3ca73b877c249d141861c 333 PRINTS PR00739 Glycosyl hydrolase family 26 signature 241 253 4.2E-13 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 AFR_15290 07d4517a2fc3ca73b877c249d141861c 333 PRINTS PR00739 Glycosyl hydrolase family 26 signature 105 119 4.2E-13 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 AFR_15290 07d4517a2fc3ca73b877c249d141861c 333 PRINTS PR00739 Glycosyl hydrolase family 26 signature 204 227 4.2E-13 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 AFR_15290 07d4517a2fc3ca73b877c249d141861c 333 PRINTS PR00739 Glycosyl hydrolase family 26 signature 177 194 4.2E-13 T 12-10-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 AFR_15290 07d4517a2fc3ca73b877c249d141861c 333 Gene3D G3DSA:3.20.20.80 21 332 1.1E-79 T 12-10-2018 AFR_13670 cc3e9953ae287fb19a17ce2d8f2060af 489 Pfam PF06081 Aromatic acid exporter family member 1 23 160 4.3E-11 T 12-10-2018 IPR010343 Aromatic acid exporter family member 1 AFR_02920 ef94fabf63457e5fb882be7e96abc2b0 311 Hamap MF_00361 NAD kinase [nadK]. 8 287 23.857 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_02920 ef94fabf63457e5fb882be7e96abc2b0 311 Gene3D G3DSA:3.40.50.10330 59 276 1.2E-58 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_02920 ef94fabf63457e5fb882be7e96abc2b0 311 Pfam PF01513 ATP-NAD kinase 52 265 4.8E-34 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_02920 ef94fabf63457e5fb882be7e96abc2b0 311 SUPERFAMILY SSF111331 57 273 3.14E-53 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_02920 ef94fabf63457e5fb882be7e96abc2b0 311 Gene3D G3DSA:2.60.200.30 128 262 1.2E-58 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_17685 e347675f56104457606f08114111393d 149 SUPERFAMILY SSF54593 1 131 3.09E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_17685 e347675f56104457606f08114111393d 149 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 7.5E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_17685 e347675f56104457606f08114111393d 149 Gene3D G3DSA:3.10.180.10 3 130 8.4E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_35400 60a3e678f105497d1bb558f8908e5a5f 195 SUPERFAMILY SSF56112 4 159 1.78E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_35400 60a3e678f105497d1bb558f8908e5a5f 195 Gene3D G3DSA:1.10.510.10 3 144 5.6E-7 T 12-10-2018 AFR_35400 60a3e678f105497d1bb558f8908e5a5f 195 Pfam PF01636 Phosphotransferase enzyme family 6 99 1.7E-7 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_35400 60a3e678f105497d1bb558f8908e5a5f 195 Pfam PF01636 Phosphotransferase enzyme family 101 146 1.5E-6 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 38 774 2.4E-250 T 12-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 Pfam PF00384 Molybdopterin oxidoreductase 141 509 5.5E-28 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 Gene3D G3DSA:3.40.50.740 152 607 3.0E-71 T 12-10-2018 AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 SUPERFAMILY SSF53706 79 652 2.62E-132 T 12-10-2018 AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 Pfam PF01568 Molydopterin dinucleotide binding domain 661 746 1.9E-8 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 Gene3D G3DSA:3.40.228.10 216 433 3.0E-71 T 12-10-2018 AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 PIRSF PIRSF000144 23 778 9.9E-298 T 12-10-2018 AFR_27775 5096cf204b1baa1ceabd954cd65c289e 779 SUPERFAMILY SSF50692 653 777 5.42E-15 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 48 6.3E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 Pfam PF13377 Periplasmic binding protein-like domain 169 330 2.9E-44 T 12-10-2018 AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 SUPERFAMILY SSF53822 62 333 5.22E-81 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 Gene3D G3DSA:3.40.50.2300 160 325 6.5E-74 T 12-10-2018 AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 SMART SM00354 3 71 4.7E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 SUPERFAMILY SSF47413 3 51 6.03E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 Gene3D G3DSA:3.40.50.2300 76 321 6.5E-74 T 12-10-2018 AFR_19970 d4a2a8c7cbd9eb11d106af0c64396c75 335 Gene3D G3DSA:1.10.260.40 2 58 1.4E-16 T 12-10-2018 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 336 503 2.4E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 Gene3D G3DSA:1.10.287.950 217 532 3.0E-65 T 12-10-2018 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 Pfam PF00672 HAMP domain 217 263 7.3E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 SMART SM00283 277 531 2.9E-43 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 Pfam PF12729 Four helix bundle sensory module for signal transduction 14 159 7.0E-13 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 SUPERFAMILY SSF58104 237 530 3.27E-63 T 12-10-2018 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 4.9E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 13 38 4.9E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 193 213 4.9E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 4.9E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_22765 2f98d6bca2ce701552ad5564ef8e96fb 532 SMART SM00304 217 269 5.6E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 32 46 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 Gene3D G3DSA:3.40.50.720 129 283 4.3E-131 T 12-10-2018 AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 SUPERFAMILY SSF50129 1 141 3.09E-46 T 12-10-2018 IPR011032 GroES-like superfamily AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 Gene3D G3DSA:3.90.180.10 1 311 4.3E-131 T 12-10-2018 AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 SUPERFAMILY SSF51735 118 281 2.17E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1 113 3.6E-27 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 Pfam PF00107 Zinc-binding dehydrogenase 155 277 3.4E-19 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_15110 e63b26b11696e93354118f7a0c22ece5 317 SMART SM00829 1 311 1.4E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_04635 1888cd1fc4aa07bebed877e98a8c368e 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.15 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04635 1888cd1fc4aa07bebed877e98a8c368e 37 SUPERFAMILY SSF57840 2 37 6.41E-16 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04635 1888cd1fc4aa07bebed877e98a8c368e 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 3.0E-8 T 12-10-2018 AFR_04635 1888cd1fc4aa07bebed877e98a8c368e 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 1.8E-19 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04635 1888cd1fc4aa07bebed877e98a8c368e 37 Pfam PF00444 Ribosomal protein L36 2 37 1.9E-16 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04635 1888cd1fc4aa07bebed877e98a8c368e 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_19735 1511f0373af52a72ec3a7b4eb0d474ff 359 Gene3D G3DSA:3.40.50.2000 169 340 2.9E-34 T 12-10-2018 AFR_19735 1511f0373af52a72ec3a7b4eb0d474ff 359 Pfam PF00534 Glycosyl transferases group 1 175 339 4.6E-24 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_19735 1511f0373af52a72ec3a7b4eb0d474ff 359 Gene3D G3DSA:3.40.50.2000 30 168 3.3E-6 T 12-10-2018 AFR_19735 1511f0373af52a72ec3a7b4eb0d474ff 359 SUPERFAMILY SSF53756 97 357 4.71E-48 T 12-10-2018 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 Pfam PF06628 Catalase-related immune-responsive 501 564 1.4E-21 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 Pfam PF00199 Catalase 84 469 1.4E-165 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 PRINTS PR00067 Catalase signature 159 177 1.3E-65 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 PRINTS PR00067 Catalase signature 97 120 1.3E-65 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 PRINTS PR00067 Catalase signature 401 427 1.3E-65 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 PRINTS PR00067 Catalase signature 199 217 1.3E-65 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 PRINTS PR00067 Catalase signature 369 396 1.3E-65 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 PRINTS PR00067 Catalase signature 180 197 1.3E-65 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 SUPERFAMILY SSF56634 73 588 5.1E-202 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 SMART SM01060 84 472 8.6E-250 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 Gene3D G3DSA:3.40.50.880 594 750 1.7E-30 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 414 422 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 SUPERFAMILY SSF52317 607 747 4.26E-10 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 PIRSF PIRSF038927 53 752 8.5E-289 T 12-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 Gene3D G3DSA:2.40.180.10 13 492 2.1E-194 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 Gene3D G3DSA:1.20.1370.20 498 592 3.9E-29 T 12-10-2018 AFR_23395 e33a2802b0c0e70ca126015d0ca5cd0a 752 ProSitePatterns PS00438 Catalase proximal active site signature. 120 136 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_21760 2b2a2fa6c9da259f51a90a8103999fd9 264 Pfam PF12697 Alpha/beta hydrolase family 39 249 1.0E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21760 2b2a2fa6c9da259f51a90a8103999fd9 264 SUPERFAMILY SSF53474 3 263 6.2E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21760 2b2a2fa6c9da259f51a90a8103999fd9 264 Gene3D G3DSA:3.40.50.1820 1 263 7.5E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28815 ef917121233f7c37dab4de6424c2f21d 293 Pfam PF00005 ABC transporter 12 150 2.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_28815 ef917121233f7c37dab4de6424c2f21d 293 SUPERFAMILY SSF52540 1 217 5.83E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28815 ef917121233f7c37dab4de6424c2f21d 293 SMART SM00382 20 198 2.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_28815 ef917121233f7c37dab4de6424c2f21d 293 Gene3D G3DSA:3.40.50.300 1 221 1.6E-53 T 12-10-2018 AFR_10485 b94f842bf1af1a6bb555cab4bb15f522 331 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 321 4.0E-118 T 12-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 AFR_10485 b94f842bf1af1a6bb555cab4bb15f522 331 Pfam PF03741 Integral membrane protein TerC family 70 274 2.0E-53 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFR_10410 8a3a14e7f7e0059c80207f3d6f8fa726 236 SUPERFAMILY SSF52540 2 233 1.59E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10410 8a3a14e7f7e0059c80207f3d6f8fa726 236 Gene3D G3DSA:3.40.50.300 1 236 2.0E-66 T 12-10-2018 AFR_10410 8a3a14e7f7e0059c80207f3d6f8fa726 236 PIRSF PIRSF039137 1 236 7.4E-111 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 AFR_10410 8a3a14e7f7e0059c80207f3d6f8fa726 236 SMART SM00382 27 214 1.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10410 8a3a14e7f7e0059c80207f3d6f8fa726 236 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_10410 8a3a14e7f7e0059c80207f3d6f8fa726 236 Pfam PF00005 ABC transporter 18 163 4.2E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_07040 6018cb6b349cf5a4c198f73ad5ab9a02 231 SUPERFAMILY SSF109604 26 182 2.03E-17 T 12-10-2018 AFR_07040 6018cb6b349cf5a4c198f73ad5ab9a02 231 Gene3D G3DSA:1.10.3210.10 28 204 1.3E-29 T 12-10-2018 AFR_07040 6018cb6b349cf5a4c198f73ad5ab9a02 231 Pfam PF13328 HD domain 37 143 1.6E-11 T 12-10-2018 IPR003607 HD/PDEase domain AFR_24335 15e54366fb11e8f8e92cd7c7adfab9b3 195 SUPERFAMILY SSF48498 86 188 5.56E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_24335 15e54366fb11e8f8e92cd7c7adfab9b3 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.5E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_24335 15e54366fb11e8f8e92cd7c7adfab9b3 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_24335 15e54366fb11e8f8e92cd7c7adfab9b3 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_24335 15e54366fb11e8f8e92cd7c7adfab9b3 195 Gene3D G3DSA:1.10.357.10 3 191 1.2E-37 T 12-10-2018 AFR_24335 15e54366fb11e8f8e92cd7c7adfab9b3 195 SUPERFAMILY SSF46689 5 77 1.74E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01075 f45ff7c07dcb58ad0e7e900cea4dfe8c 253 SUPERFAMILY SSF109604 35 181 2.77E-17 T 12-10-2018 AFR_01075 f45ff7c07dcb58ad0e7e900cea4dfe8c 253 Pfam PF13328 HD domain 48 141 9.7E-10 T 12-10-2018 IPR003607 HD/PDEase domain AFR_01075 f45ff7c07dcb58ad0e7e900cea4dfe8c 253 Gene3D G3DSA:1.10.3210.10 40 215 3.1E-24 T 12-10-2018 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 Gene3D G3DSA:3.10.290.10 3 56 3.6E-7 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 SMART SM00363 5 72 2.2E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 Pfam PF01728 FtsJ-like methyltransferase 63 244 6.0E-20 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 SUPERFAMILY SSF53335 63 247 1.74E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 PIRSF PIRSF005578 1 264 6.8E-93 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 Pfam PF01479 S4 domain 6 50 4.0E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 240 6.1E-62 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 SUPERFAMILY SSF55174 5 65 5.3E-10 T 12-10-2018 AFR_29945 5bec9c261d3665497773dc8ae15bcd9d 286 Gene3D G3DSA:3.40.50.150 57 266 1.1E-78 T 12-10-2018 AFR_03145 4ce4b5298867ea44c749cb905ef01dbd 550 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 355 521 4.0E-32 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_03145 4ce4b5298867ea44c749cb905ef01dbd 550 SMART SM00283 295 549 6.6E-46 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_03145 4ce4b5298867ea44c749cb905ef01dbd 550 SMART SM00304 235 287 3.0E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_03145 4ce4b5298867ea44c749cb905ef01dbd 550 Pfam PF12729 Four helix bundle sensory module for signal transduction 33 208 5.3E-15 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFR_03145 4ce4b5298867ea44c749cb905ef01dbd 550 SUPERFAMILY SSF58104 255 548 1.2E-61 T 12-10-2018 AFR_03145 4ce4b5298867ea44c749cb905ef01dbd 550 Gene3D G3DSA:1.10.287.950 235 550 2.5E-59 T 12-10-2018 AFR_32990 f666b545487dfdcc642b642ddc7c0fdc 183 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 45 174 7.9E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_32990 f666b545487dfdcc642b642ddc7c0fdc 183 SUPERFAMILY SSF48498 43 176 6.56E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_32990 f666b545487dfdcc642b642ddc7c0fdc 183 Gene3D G3DSA:1.10.357.10 35 176 3.7E-25 T 12-10-2018 AFR_32990 f666b545487dfdcc642b642ddc7c0fdc 183 SUPERFAMILY SSF46689 1 35 2.77E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_32990 f666b545487dfdcc642b642ddc7c0fdc 183 Gene3D G3DSA:1.10.10.60 1 34 2.3E-13 T 12-10-2018 AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 SMART SM00642 158 568 3.0E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 SUPERFAMILY SSF81296 5 146 2.49E-47 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 4.4E-20 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 Pfam PF00128 Alpha amylase, catalytic domain 188 528 2.0E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 Gene3D G3DSA:3.20.20.80 138 582 2.0E-178 T 12-10-2018 AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 699 5.2E-301 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 Gene3D G3DSA:2.60.40.1180 588 700 1.0E-12 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 Gene3D G3DSA:2.60.40.10 1 136 5.6E-49 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 SUPERFAMILY SSF51011 589 700 1.65E-21 T 12-10-2018 AFR_24665 0aff0a335c047896e8387a711fb0d3c5 702 SUPERFAMILY SSF51445 133 576 1.81E-128 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 490 521 1.0E-6 T 12-10-2018 IPR006530 YD repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 533 570 2.0E-4 T 12-10-2018 IPR006530 YD repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 319 344 0.0012 T 12-10-2018 IPR006530 YD repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 294 332 4.2E-7 T 12-10-2018 IPR006530 YD repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 908 984 4.1E-18 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 Gene3D G3DSA:2.180.10.10 873 984 1.0E-19 T 12-10-2018 AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 Gene3D G3DSA:2.180.10.10 429 632 3.0E-10 T 12-10-2018 AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 Pfam PF05593 RHS Repeat 294 331 1.4E-7 T 12-10-2018 IPR031325 RHS repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 Pfam PF05593 RHS Repeat 253 287 8.0E-6 T 12-10-2018 IPR031325 RHS repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 Pfam PF05593 RHS Repeat 315 352 5.2E-8 T 12-10-2018 IPR031325 RHS repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 Pfam PF05593 RHS Repeat 491 519 1.7E-7 T 12-10-2018 IPR031325 RHS repeat AFR_13240 0cf65ad0a755c811a412e22c697ec6e8 1082 Pfam PF05593 RHS Repeat 533 570 4.9E-5 T 12-10-2018 IPR031325 RHS repeat AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 245 258 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 SUPERFAMILY SSF53613 1 296 2.96E-63 T 12-10-2018 IPR029056 Ribokinase-like AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 Gene3D G3DSA:3.40.1190.20 1 298 7.5E-68 T 12-10-2018 IPR029056 Ribokinase-like AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 Pfam PF00294 pfkB family carbohydrate kinase 3 290 2.2E-44 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 PRINTS PR00990 Ribokinase signature 5 26 4.3E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 PRINTS PR00990 Ribokinase signature 178 193 4.3E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 PRINTS PR00990 Ribokinase signature 216 227 4.3E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_22505 522524d90291c9219ff9f65bb520ad1a 298 PRINTS PR00990 Ribokinase signature 33 52 4.3E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_32890 8899d3c324395862878c2a37e7bca2e3 198 Pfam PF00857 Isochorismatase family 4 146 1.4E-35 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_32890 8899d3c324395862878c2a37e7bca2e3 198 Gene3D G3DSA:3.40.50.850 1 197 3.9E-46 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_32890 8899d3c324395862878c2a37e7bca2e3 198 SUPERFAMILY SSF52499 3 195 5.36E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_40955 9757a04681de40cb90bf91bf0a124f96 139 SUPERFAMILY SSF82607 29 111 5.89E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_40955 9757a04681de40cb90bf91bf0a124f96 139 Gene3D G3DSA:3.30.1310.10 21 118 3.4E-5 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_40955 9757a04681de40cb90bf91bf0a124f96 139 Pfam PF02575 YbaB/EbfC DNA-binding family 34 110 7.8E-9 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_23620 419f1c2cf61aceaab263f3fc8c08395f 355 Pfam PF01032 FecCD transport family 41 349 2.9E-87 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_23620 419f1c2cf61aceaab263f3fc8c08395f 355 SUPERFAMILY SSF81345 24 349 1.44E-77 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_23620 419f1c2cf61aceaab263f3fc8c08395f 355 Gene3D G3DSA:1.10.3470.10 27 353 6.1E-93 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_40670 9646841cb2dadc9ce8017bdcc9b6f80f 160 Pfam PF01381 Helix-turn-helix 15 66 6.7E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_40670 9646841cb2dadc9ce8017bdcc9b6f80f 160 SUPERFAMILY SSF47413 7 67 8.16E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_40670 9646841cb2dadc9ce8017bdcc9b6f80f 160 Gene3D G3DSA:1.10.260.40 6 73 4.9E-19 T 12-10-2018 AFR_40670 9646841cb2dadc9ce8017bdcc9b6f80f 160 SMART SM00530 14 69 1.4E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_15880 b62778a2a29bc8dd80fa521336cffee7 222 Gene3D G3DSA:3.40.50.12740 2 208 2.5E-30 T 12-10-2018 AFR_15880 b62778a2a29bc8dd80fa521336cffee7 222 Pfam PF00072 Response regulator receiver domain 4 115 8.5E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_15880 b62778a2a29bc8dd80fa521336cffee7 222 SUPERFAMILY SSF52172 2 127 1.14E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_15880 b62778a2a29bc8dd80fa521336cffee7 222 SMART SM00448 2 115 2.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_15880 b62778a2a29bc8dd80fa521336cffee7 222 PIRSF PIRSF006171 1 222 2.7E-76 T 12-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 AFR_00810 10c439a741314e2bdfee79a46304c206 139 SUPERFAMILY SSF54637 21 137 3.34E-25 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_00810 10c439a741314e2bdfee79a46304c206 139 Gene3D G3DSA:3.10.129.10 2 138 2.1E-44 T 12-10-2018 AFR_00810 10c439a741314e2bdfee79a46304c206 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 22 135 2.8E-25 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFR_00810 10c439a741314e2bdfee79a46304c206 139 Pfam PF03061 Thioesterase superfamily 49 128 2.2E-12 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 Gene3D G3DSA:3.40.190.10 99 285 8.8E-39 T 12-10-2018 AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 Gene3D G3DSA:3.40.190.10 171 273 8.8E-39 T 12-10-2018 AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 Gene3D G3DSA:1.10.10.10 7 96 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 SUPERFAMILY SSF53850 98 298 1.26E-40 T 12-10-2018 AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 Pfam PF03466 LysR substrate binding domain 96 298 2.1E-44 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 SUPERFAMILY SSF46785 8 117 1.41E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_25875 83cc9b88ac4b6cb1bc4d320e90be3cce 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 2.2E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_09485 bce0a15c5aff99f17c13c9f45242c6a1 418 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 47 204 1.0E-16 T 12-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 AFR_09485 bce0a15c5aff99f17c13c9f45242c6a1 418 Pfam PF01435 Peptidase family M48 208 412 5.9E-28 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFR_09485 bce0a15c5aff99f17c13c9f45242c6a1 418 Gene3D G3DSA:3.30.2010.10 203 285 4.8E-26 T 12-10-2018 AFR_27960 2da7c074918939bf30b7ffa2d1584828 306 Pfam PF14589 Polysulfide reductase 9 277 2.2E-12 T 12-10-2018 IPR032796 Polysulfide reductase AFR_27960 2da7c074918939bf30b7ffa2d1584828 306 Gene3D G3DSA:1.20.1630.10 7 264 1.2E-16 T 12-10-2018 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 PRINTS PR00171 Sugar transporter signature 33 43 5.2E-15 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 PRINTS PR00171 Sugar transporter signature 270 280 5.2E-15 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 PRINTS PR00171 Sugar transporter signature 382 394 5.2E-15 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 PRINTS PR00171 Sugar transporter signature 116 135 5.2E-15 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 ProSitePatterns PS00217 Sugar transport proteins signature 2. 121 146 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 SUPERFAMILY SSF103473 17 456 8.37E-68 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 Gene3D G3DSA:1.20.1250.20 14 462 1.3E-110 T 12-10-2018 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 5 454 8.8E-96 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFR_28760 8d6bb34fa1094ecea328ae8386fa33bb 471 Pfam PF00083 Sugar (and other) transporter 25 456 4.5E-93 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 317 8.1E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 SUPERFAMILY SSF158472 193 240 3.66E-6 T 12-10-2018 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 Gene3D G3DSA:1.10.287.130 195 320 7.8E-28 T 12-10-2018 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 497 3.3E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 SMART SM00304 191 244 2.8E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 SUPERFAMILY SSF47384 242 317 9.81E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 Gene3D G3DSA:3.30.565.10 323 498 8.4E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 SMART SM00387 368 499 1.9E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 SMART SM00388 252 319 4.7E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 SUPERFAMILY SSF55874 308 497 1.83E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 437 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 451 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_20570 9c89095dbf0a8fc6e40c7130daa033df 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 496 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28065 3000b4693d2ebd725a4412f304297d96 393 SUPERFAMILY SSF56601 28 386 1.77E-79 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_28065 3000b4693d2ebd725a4412f304297d96 393 Pfam PF00144 Beta-lactamase 83 379 1.2E-38 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_28065 3000b4693d2ebd725a4412f304297d96 393 Gene3D G3DSA:3.40.710.10 83 370 2.0E-89 T 12-10-2018 AFR_28065 3000b4693d2ebd725a4412f304297d96 393 Gene3D G3DSA:1.20.58.710 135 233 2.0E-89 T 12-10-2018 AFR_11695 21aff9caec5af59d495bced77bb27d3a 412 Pfam PF04932 O-Antigen ligase 197 333 5.9E-15 T 12-10-2018 IPR007016 O-antigen ligase-related AFR_06300 be1b461307648bed08746d7fd9b20052 208 Gene3D G3DSA:3.40.50.720 3 207 4.1E-50 T 12-10-2018 AFR_06300 be1b461307648bed08746d7fd9b20052 208 Pfam PF13460 NAD(P)H-binding 9 195 1.1E-51 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_06300 be1b461307648bed08746d7fd9b20052 208 SUPERFAMILY SSF51735 4 205 4.74E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_31230 8869b6bb148ddc662ce90fbbf46d8fd5 144 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 20 135 9.2E-34 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III AFR_32620 60383fa33268a371ae9c904e467c6202 308 SUPERFAMILY SSF51215 37 85 5.49E-9 T 12-10-2018 IPR037923 Transcription regulator HTH-like AFR_32620 60383fa33268a371ae9c904e467c6202 308 SUPERFAMILY SSF46689 235 278 7.62E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_32620 60383fa33268a371ae9c904e467c6202 308 Pfam PF02311 AraC-like ligand binding domain 37 85 4.9E-6 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFR_32620 60383fa33268a371ae9c904e467c6202 308 SMART SM00342 195 278 6.6E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_32620 60383fa33268a371ae9c904e467c6202 308 Pfam PF12833 Helix-turn-helix domain 201 278 1.3E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_32620 60383fa33268a371ae9c904e467c6202 308 Gene3D G3DSA:1.10.10.60 178 281 3.8E-20 T 12-10-2018 AFR_01985 96d75c01b0f3b21560d5dcd8c0d5d053 405 SUPERFAMILY SSF103473 19 398 7.85E-34 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_01985 96d75c01b0f3b21560d5dcd8c0d5d053 405 Pfam PF07690 Major Facilitator Superfamily 22 234 1.8E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_01985 96d75c01b0f3b21560d5dcd8c0d5d053 405 Gene3D G3DSA:1.20.1250.20 18 197 3.1E-12 T 12-10-2018 AFR_01985 96d75c01b0f3b21560d5dcd8c0d5d053 405 Gene3D G3DSA:1.20.1250.20 211 394 2.8E-19 T 12-10-2018 AFR_07835 20b9d29891df12779e444b696e18f122 253 Pfam PF09685 Domain of unknown function (DUF4870) 144 252 1.5E-25 T 12-10-2018 IPR019109 Protein of unknown function DUF4870 AFR_04005 7ddbdb8aa0f293e776047c3ea9439945 115 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 109 3.5E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_04005 7ddbdb8aa0f293e776047c3ea9439945 115 Gene3D G3DSA:3.10.180.10 6 114 1.7E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_04005 7ddbdb8aa0f293e776047c3ea9439945 115 SUPERFAMILY SSF54593 9 114 3.62E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_39710 18dc051b9be492fe75e4e47259dc5fd6 195 Pfam PF01195 Peptidyl-tRNA hydrolase 8 192 4.5E-55 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFR_39710 18dc051b9be492fe75e4e47259dc5fd6 195 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 6 186 33.863 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFR_39710 18dc051b9be492fe75e4e47259dc5fd6 195 Gene3D G3DSA:3.40.50.1470 4 195 1.9E-66 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 AFR_39710 18dc051b9be492fe75e4e47259dc5fd6 195 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 8 193 5.5E-55 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFR_39710 18dc051b9be492fe75e4e47259dc5fd6 195 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 115 125 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AFR_39710 18dc051b9be492fe75e4e47259dc5fd6 195 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 19 32 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AFR_39710 18dc051b9be492fe75e4e47259dc5fd6 195 SUPERFAMILY SSF53178 6 193 7.32E-64 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 SUPERFAMILY SSF46458 7 131 1.56E-33 T 12-10-2018 IPR009050 Globin-like superfamily AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 266 1.3E-15 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 PRINTS PR00410 Phenol hydroxylase reductase family signature 272 281 1.3E-15 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 PRINTS PR00410 Phenol hydroxylase reductase family signature 168 180 1.3E-15 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 Pfam PF00042 Globin 6 97 6.6E-14 T 12-10-2018 IPR000971 Globin GO:0020037 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 Pfam PF00970 Oxidoreductase FAD-binding domain 144 236 2.2E-14 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 SUPERFAMILY SSF63380 141 236 4.26E-23 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 Gene3D G3DSA:1.10.490.10 4 136 6.2E-38 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 Gene3D G3DSA:2.40.30.10 137 234 1.9E-23 T 12-10-2018 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 Gene3D G3DSA:3.40.50.80 236 368 2.3E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 SUPERFAMILY SSF52343 241 367 2.1E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 187 194 6.0E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 247 266 6.0E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 272 281 6.0E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFR_42185 9e15d17d8c5da8ec1739f95c945a56aa 368 Pfam PF00175 Oxidoreductase NAD-binding domain 248 348 4.6E-14 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_10465 710d5c0530724248055c4d2d973bc392 705 SUPERFAMILY SSF46600 656 697 4.84E-10 T 12-10-2018 IPR036876 UVR domain superfamily AFR_10465 710d5c0530724248055c4d2d973bc392 705 SUPERFAMILY SSF52540 12 421 7.0E-129 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10465 710d5c0530724248055c4d2d973bc392 705 Gene3D G3DSA:3.40.50.300 280 420 5.7E-53 T 12-10-2018 AFR_10465 710d5c0530724248055c4d2d973bc392 705 Pfam PF02151 UvrB/uvrC motif 661 695 3.8E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 AFR_10465 710d5c0530724248055c4d2d973bc392 705 Hamap MF_00204 UvrABC system protein B [uvrB]. 10 695 42.28 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 AFR_10465 710d5c0530724248055c4d2d973bc392 705 SUPERFAMILY SSF52540 40 590 8.46E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10465 710d5c0530724248055c4d2d973bc392 705 SMART SM00490 466 552 1.5E-18 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_10465 710d5c0530724248055c4d2d973bc392 705 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 11 693 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 AFR_10465 710d5c0530724248055c4d2d973bc392 705 Pfam PF04851 Type III restriction enzyme, res subunit 22 134 6.5E-9 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFR_10465 710d5c0530724248055c4d2d973bc392 705 SMART SM00487 16 431 1.8E-25 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_10465 710d5c0530724248055c4d2d973bc392 705 Pfam PF12344 Ultra-violet resistance protein B 558 599 5.8E-20 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain AFR_10465 710d5c0530724248055c4d2d973bc392 705 Gene3D G3DSA:4.10.860.10 646 697 3.7E-8 T 12-10-2018 AFR_10465 710d5c0530724248055c4d2d973bc392 705 Gene3D G3DSA:3.40.50.300 4 249 1.8E-69 T 12-10-2018 AFR_10465 710d5c0530724248055c4d2d973bc392 705 Pfam PF00271 Helicase conserved C-terminal domain 448 550 1.3E-17 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_10465 710d5c0530724248055c4d2d973bc392 705 Gene3D G3DSA:3.40.50.300 421 602 3.0E-49 T 12-10-2018 AFR_18010 5f3a907555b720c0254d3d5ee7019a42 427 SUPERFAMILY SSF52266 201 421 1.12E-42 T 12-10-2018 AFR_18010 5f3a907555b720c0254d3d5ee7019a42 427 Gene3D G3DSA:3.40.50.1110 189 419 3.8E-30 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_18010 5f3a907555b720c0254d3d5ee7019a42 427 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 207 411 9.5E-21 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_09015 5ddb310c7706021d096e0fda1cbd0a7e 621 Pfam PF13599 Pentapeptide repeats (9 copies) 102 168 4.7E-7 T 12-10-2018 IPR001646 Pentapeptide repeat AFR_09015 5ddb310c7706021d096e0fda1cbd0a7e 621 SUPERFAMILY SSF141571 101 231 3.53E-10 T 12-10-2018 AFR_09015 5ddb310c7706021d096e0fda1cbd0a7e 621 Gene3D G3DSA:2.160.20.100 101 270 7.4E-9 T 12-10-2018 AFR_18710 eaaae6f6bcc709e6267b4687cc822287 405 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 36 384 4.3E-97 T 12-10-2018 AFR_18710 eaaae6f6bcc709e6267b4687cc822287 405 SUPERFAMILY SSF48208 7 400 4.37E-89 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_18710 eaaae6f6bcc709e6267b4687cc822287 405 Gene3D G3DSA:1.50.10.10 5 405 2.2E-146 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_24135 1fddc84c9180933ce0cc7ea80be7c328 212 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 2 196 7.2E-33 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 AFR_24135 1fddc84c9180933ce0cc7ea80be7c328 212 Gene3D G3DSA:1.10.3630.10 1 117 3.6E-7 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily AFR_06475 0eb2b5b93936278bb82f7758bef14139 156 SUPERFAMILY SSF52833 4 153 1.5E-46 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_06475 0eb2b5b93936278bb82f7758bef14139 156 Pfam PF00578 AhpC/TSA family 8 135 2.5E-36 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_06475 0eb2b5b93936278bb82f7758bef14139 156 Gene3D G3DSA:3.40.30.10 6 154 7.3E-46 T 12-10-2018 AFR_06475 0eb2b5b93936278bb82f7758bef14139 156 PIRSF PIRSF000239 2 151 6.1E-22 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_17750 ca54ab5f795e009f80df5b55726a7586 309 Pfam PF02016 LD-carboxypeptidase 17 294 1.5E-62 T 12-10-2018 IPR003507 Peptidase family S66 AFR_17750 ca54ab5f795e009f80df5b55726a7586 309 SUPERFAMILY SSF52317 5 160 4.58E-39 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_17750 ca54ab5f795e009f80df5b55726a7586 309 Gene3D G3DSA:3.50.30.60 169 302 2.2E-28 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_17750 ca54ab5f795e009f80df5b55726a7586 309 SUPERFAMILY SSF141986 172 301 7.72E-29 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_17750 ca54ab5f795e009f80df5b55726a7586 309 Gene3D G3DSA:3.40.50.10740 4 158 1.5E-42 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal AFR_17750 ca54ab5f795e009f80df5b55726a7586 309 PIRSF PIRSF028757 5 309 2.7E-63 T 12-10-2018 IPR003507 Peptidase family S66 AFR_13870 e93d132f0c8a7c772c14c17eca2db0fc 247 Gene3D G3DSA:2.20.25.570 135 205 2.6E-40 T 12-10-2018 AFR_13870 e93d132f0c8a7c772c14c17eca2db0fc 247 SUPERFAMILY SSF53335 4 245 5.47E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_13870 e93d132f0c8a7c772c14c17eca2db0fc 247 Gene3D G3DSA:3.40.50.150 29 237 2.6E-40 T 12-10-2018 AFR_13870 e93d132f0c8a7c772c14c17eca2db0fc 247 Pfam PF13649 Methyltransferase domain 31 127 2.9E-20 T 12-10-2018 AFR_18615 b515a5934ebee8f16dc667b3a43ecbe4 151 Gene3D G3DSA:3.10.450.50 1 148 3.2E-37 T 12-10-2018 AFR_18615 b515a5934ebee8f16dc667b3a43ecbe4 151 SUPERFAMILY SSF54427 2 141 3.57E-22 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_18615 b515a5934ebee8f16dc667b3a43ecbe4 151 Pfam PF13577 SnoaL-like domain 3 134 1.0E-19 T 12-10-2018 IPR037401 SnoaL-like domain AFR_33520 d692a5779de4829d3a43eb9168795738 266 PIRSF PIRSF006648 9 265 3.5E-28 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_33520 d692a5779de4829d3a43eb9168795738 266 Pfam PF01061 ABC-2 type transporter 15 221 2.2E-30 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_13135 de63121125568dc53e112db6a0128c22 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.1E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13135 de63121125568dc53e112db6a0128c22 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.1E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13135 de63121125568dc53e112db6a0128c22 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.1E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13135 de63121125568dc53e112db6a0128c22 122 SUPERFAMILY SSF46955 1 111 4.4E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_13135 de63121125568dc53e112db6a0128c22 122 SMART SM00422 1 69 7.7E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13135 de63121125568dc53e112db6a0128c22 122 Pfam PF13411 MerR HTH family regulatory protein 1 66 1.6E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13135 de63121125568dc53e112db6a0128c22 122 Gene3D G3DSA:1.10.1660.10 1 120 2.9E-26 T 12-10-2018 AFR_13135 de63121125568dc53e112db6a0128c22 122 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_37720 faafd565a1703f8d06881956bab48c0d 210 SMART SM00554 114 209 3.8E-31 T 12-10-2018 IPR000782 FAS1 domain AFR_37720 faafd565a1703f8d06881956bab48c0d 210 Gene3D G3DSA:2.30.180.10 53 210 6.3E-49 T 12-10-2018 IPR036378 FAS1 domain superfamily AFR_37720 faafd565a1703f8d06881956bab48c0d 210 SUPERFAMILY SSF82153 72 209 1.83E-34 T 12-10-2018 IPR036378 FAS1 domain superfamily AFR_37720 faafd565a1703f8d06881956bab48c0d 210 Pfam PF02469 Fasciclin domain 90 208 2.1E-30 T 12-10-2018 IPR000782 FAS1 domain AFR_12580 5b8c8a7ae42d5694b6e7575f36ad2ff7 289 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 141 277 7.1E-16 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFR_12580 5b8c8a7ae42d5694b6e7575f36ad2ff7 289 SUPERFAMILY SSF56529 99 277 6.28E-30 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_12580 5b8c8a7ae42d5694b6e7575f36ad2ff7 289 Gene3D G3DSA:3.90.850.10 66 279 1.3E-59 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_20710 e771fd783b82558ca8518ebd89c7a9fd 299 Gene3D G3DSA:3.20.20.150 3 297 1.2E-61 T 12-10-2018 AFR_20710 e771fd783b82558ca8518ebd89c7a9fd 299 SUPERFAMILY SSF51658 6 282 2.09E-49 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_20710 e771fd783b82558ca8518ebd89c7a9fd 299 Pfam PF01261 Xylose isomerase-like TIM barrel 33 224 2.5E-30 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_09650 17e246323ac463d771217d8d66aac837 468 Gene3D G3DSA:3.20.20.70 219 468 4.6E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_09650 17e246323ac463d771217d8d66aac837 468 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 36 467 9.0E-200 T 12-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFR_09650 17e246323ac463d771217d8d66aac837 468 Pfam PF01474 Class-II DAHP synthetase family 36 463 3.1E-186 T 12-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFR_09650 17e246323ac463d771217d8d66aac837 468 SUPERFAMILY SSF51569 30 467 3.59E-186 T 12-10-2018 AFR_12950 343634183fe73eacc9f01feb613b8a3e 263 Pfam PF12697 Alpha/beta hydrolase family 43 255 1.2E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_12950 343634183fe73eacc9f01feb613b8a3e 263 Gene3D G3DSA:3.40.50.1820 37 263 3.0E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12950 343634183fe73eacc9f01feb613b8a3e 263 SUPERFAMILY SSF53474 37 260 1.5E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29140 e4e2b659d5208d56606264a3b0ad7c5d 231 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 7.8E-20 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_29140 e4e2b659d5208d56606264a3b0ad7c5d 231 SUPERFAMILY SSF51735 1 202 1.76E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29140 e4e2b659d5208d56606264a3b0ad7c5d 231 Gene3D G3DSA:3.40.50.720 1 197 6.0E-50 T 12-10-2018 AFR_21135 b42878634ab18da80252812083387eea 281 SUPERFAMILY SSF53335 12 211 3.68E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_21135 b42878634ab18da80252812083387eea 281 Pfam PF13649 Methyltransferase domain 52 148 1.7E-18 T 12-10-2018 AFR_21135 b42878634ab18da80252812083387eea 281 Gene3D G3DSA:3.40.50.150 24 211 3.4E-35 T 12-10-2018 AFR_09035 7dfc5c1d35c19727a3c27f077eddcd4d 276 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 19 276 5.2E-87 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFR_09035 7dfc5c1d35c19727a3c27f077eddcd4d 276 SUPERFAMILY SSF51621 15 275 5.1E-99 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_09035 7dfc5c1d35c19727a3c27f077eddcd4d 276 Gene3D G3DSA:3.20.20.60 13 276 4.0E-106 T 12-10-2018 AFR_09035 7dfc5c1d35c19727a3c27f077eddcd4d 276 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 16 276 41.28 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFR_09035 7dfc5c1d35c19727a3c27f077eddcd4d 276 PIRSF PIRSF000388 10 276 2.9E-107 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFR_09035 7dfc5c1d35c19727a3c27f077eddcd4d 276 Pfam PF02548 Ketopantoate hydroxymethyltransferase 15 271 1.5E-103 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFR_00960 d3e2410f4f45d99159046c4ea64c5f4c 376 Gene3D G3DSA:3.40.50.2000 13 172 2.8E-48 T 12-10-2018 AFR_00960 d3e2410f4f45d99159046c4ea64c5f4c 376 Gene3D G3DSA:3.40.50.2000 173 346 2.8E-48 T 12-10-2018 AFR_00960 d3e2410f4f45d99159046c4ea64c5f4c 376 Pfam PF13439 Glycosyltransferase Family 4 15 175 9.9E-15 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_00960 d3e2410f4f45d99159046c4ea64c5f4c 376 SUPERFAMILY SSF53756 2 359 2.37E-60 T 12-10-2018 AFR_00960 d3e2410f4f45d99159046c4ea64c5f4c 376 Pfam PF00534 Glycosyl transferases group 1 193 343 9.5E-23 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_17365 40125083463bad9599a5321e294de6d5 358 Gene3D G3DSA:3.90.180.10 115 341 5.2E-28 T 12-10-2018 AFR_17365 40125083463bad9599a5321e294de6d5 358 SUPERFAMILY SSF51735 158 288 4.18E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17365 40125083463bad9599a5321e294de6d5 358 Gene3D G3DSA:3.40.50.720 138 298 5.2E-28 T 12-10-2018 AFR_17365 40125083463bad9599a5321e294de6d5 358 Pfam PF00107 Zinc-binding dehydrogenase 174 271 4.7E-13 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_22910 10b62e7e356b3cd46d75d9978dc9166e 188 Gene3D G3DSA:2.60.120.10 75 187 6.2E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_22910 10b62e7e356b3cd46d75d9978dc9166e 188 SUPERFAMILY SSF51182 75 176 2.89E-17 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_22910 10b62e7e356b3cd46d75d9978dc9166e 188 Pfam PF01381 Helix-turn-helix 15 68 1.3E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_22910 10b62e7e356b3cd46d75d9978dc9166e 188 Gene3D G3DSA:1.10.260.40 2 74 1.6E-19 T 12-10-2018 AFR_22910 10b62e7e356b3cd46d75d9978dc9166e 188 Pfam PF07883 Cupin domain 115 177 1.1E-9 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_22910 10b62e7e356b3cd46d75d9978dc9166e 188 SMART SM00530 13 68 3.5E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_22910 10b62e7e356b3cd46d75d9978dc9166e 188 SUPERFAMILY SSF47413 5 74 2.45E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_40875 84163cc7c24748eb93965b4cb3f0d5d0 333 SUPERFAMILY SSF55729 5 152 7.0E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40875 84163cc7c24748eb93965b4cb3f0d5d0 333 SUPERFAMILY SSF55729 86 323 1.6E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40875 84163cc7c24748eb93965b4cb3f0d5d0 333 Pfam PF00583 Acetyltransferase (GNAT) family 87 144 3.1E-5 T 12-10-2018 IPR000182 GNAT domain AFR_40875 84163cc7c24748eb93965b4cb3f0d5d0 333 Gene3D G3DSA:3.40.630.30 190 326 4.1E-13 T 12-10-2018 AFR_40875 84163cc7c24748eb93965b4cb3f0d5d0 333 Gene3D G3DSA:3.40.630.30 2 187 1.1E-12 T 12-10-2018 AFR_21165 6bfef10788810f0548001009336bfb9d 832 Gene3D G3DSA:3.40.50.300 26 199 6.3E-39 T 12-10-2018 AFR_21165 6bfef10788810f0548001009336bfb9d 832 Pfam PF12029 Domain of unknown function (DUF3516) 374 828 3.5E-210 T 12-10-2018 IPR021904 Protein of unknown function DUF3516 AFR_21165 6bfef10788810f0548001009336bfb9d 832 Pfam PF00271 Helicase conserved C-terminal domain 284 363 3.4E-6 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_21165 6bfef10788810f0548001009336bfb9d 832 SUPERFAMILY SSF52540 45 376 8.88E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21165 6bfef10788810f0548001009336bfb9d 832 Gene3D G3DSA:3.40.50.300 200 388 2.6E-43 T 12-10-2018 AFR_21165 6bfef10788810f0548001009336bfb9d 832 Pfam PF00270 DEAD/DEAH box helicase 33 178 1.6E-10 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_21165 6bfef10788810f0548001009336bfb9d 832 SMART SM00487 27 211 7.5E-18 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_21165 6bfef10788810f0548001009336bfb9d 832 SMART SM00490 277 363 2.5E-13 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_40220 d169dd9f9d7b7ab1614a125334e5d227 361 Gene3D G3DSA:3.40.50.720 1 305 1.6E-26 T 12-10-2018 AFR_40220 d169dd9f9d7b7ab1614a125334e5d227 361 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 225 3.3E-13 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_40220 d169dd9f9d7b7ab1614a125334e5d227 361 SUPERFAMILY SSF51735 2 304 1.5E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19375 5adee030ef3db61804e4572fef1d5556 302 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 268 7.7E-34 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFR_19375 5adee030ef3db61804e4572fef1d5556 302 SUPERFAMILY SSF51735 95 269 6.87E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19375 5adee030ef3db61804e4572fef1d5556 302 Gene3D G3DSA:3.40.50.720 93 275 3.9E-53 T 12-10-2018 AFR_19375 5adee030ef3db61804e4572fef1d5556 302 Gene3D G3DSA:3.40.50.720 61 299 3.9E-53 T 12-10-2018 AFR_12365 909e0b9edec52a80dfca63707e5a3d08 390 SUPERFAMILY SSF81606 184 389 4.18E-9 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_12365 909e0b9edec52a80dfca63707e5a3d08 390 Gene3D G3DSA:3.30.450.40 40 157 6.1E-8 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_12365 909e0b9edec52a80dfca63707e5a3d08 390 SMART SM00331 174 389 2.2E-29 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_12365 909e0b9edec52a80dfca63707e5a3d08 390 Gene3D G3DSA:3.60.40.10 170 388 1.1E-49 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_12365 909e0b9edec52a80dfca63707e5a3d08 390 SUPERFAMILY SSF55781 18 150 2.18E-9 T 12-10-2018 AFR_12365 909e0b9edec52a80dfca63707e5a3d08 390 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 203 389 3.7E-39 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_02835 be486f2521f69ccf263ac50b8c2fd5c8 118 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 111 2.2E-26 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFR_02835 be486f2521f69ccf263ac50b8c2fd5c8 118 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 116 19.106 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFR_02835 be486f2521f69ccf263ac50b8c2fd5c8 118 TIGRFAM TIGR00494 crcB: protein CrcB 4 115 8.6E-24 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFR_06000 2fe859315168d0456233a43738ee6bae 328 SUPERFAMILY SSF46689 229 273 6.27E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06000 2fe859315168d0456233a43738ee6bae 328 Pfam PF01965 DJ-1/PfpI family 11 184 3.2E-21 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_06000 2fe859315168d0456233a43738ee6bae 328 SUPERFAMILY SSF52317 10 205 6.7E-48 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_06000 2fe859315168d0456233a43738ee6bae 328 Pfam PF12833 Helix-turn-helix domain 245 323 2.2E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_06000 2fe859315168d0456233a43738ee6bae 328 SMART SM00342 239 322 3.5E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_06000 2fe859315168d0456233a43738ee6bae 328 SUPERFAMILY SSF46689 276 326 9.73E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06000 2fe859315168d0456233a43738ee6bae 328 Gene3D G3DSA:1.10.10.60 226 328 7.0E-23 T 12-10-2018 AFR_06000 2fe859315168d0456233a43738ee6bae 328 Gene3D G3DSA:3.40.50.880 4 212 5.1E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_24590 114db285c5ac87b2420552dc262984db 132 Gene3D G3DSA:1.10.1740.70 1 62 1.2E-10 T 12-10-2018 AFR_24590 114db285c5ac87b2420552dc262984db 132 SUPERFAMILY SSF140376 3 61 8.89E-17 T 12-10-2018 IPR037205 ChaB superfamily AFR_24590 114db285c5ac87b2420552dc262984db 132 Pfam PF06150 ChaB 7 61 6.6E-20 T 12-10-2018 IPR009317 ChaB AFR_24590 114db285c5ac87b2420552dc262984db 132 Pfam PF07498 Rho termination factor, N-terminal domain 94 123 6.2E-7 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFR_33315 393616fb1a38fd26a7fcc3beadf5dcd3 195 Pfam PF07920 Protein of unknown function (DUF1684) 50 191 6.9E-39 T 12-10-2018 IPR012467 Protein of unknown function DUF1684 AFR_09970 5eed88af8cecb1263b3d6cf0cae8013e 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 136 1.1E-41 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFR_09970 5eed88af8cecb1263b3d6cf0cae8013e 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 133 3.0E-51 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFR_09970 5eed88af8cecb1263b3d6cf0cae8013e 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 2.3E-19 T 12-10-2018 IPR020603 MraZ domain AFR_09970 5eed88af8cecb1263b3d6cf0cae8013e 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 136 8.2E-18 T 12-10-2018 IPR020603 MraZ domain AFR_09970 5eed88af8cecb1263b3d6cf0cae8013e 143 Gene3D G3DSA:2.40.330.20 1 139 6.5E-47 T 12-10-2018 IPR038619 MraZ superfamily AFR_09970 5eed88af8cecb1263b3d6cf0cae8013e 143 SUPERFAMILY SSF89447 1 136 3.51E-47 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFR_09970 5eed88af8cecb1263b3d6cf0cae8013e 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 53.333 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 SUPERFAMILY SSF54427 166 278 3.6E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 SUPERFAMILY SSF88659 74 158 5.98E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 156 7.1E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 Pfam PF08281 Sigma-70, region 4 105 154 8.2E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 Pfam PF04542 Sigma-70 region 2 9 72 1.5E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 SUPERFAMILY SSF88946 7 90 1.49E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 Gene3D G3DSA:1.10.10.10 82 160 3.1E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 Gene3D G3DSA:3.10.450.50 164 282 8.2E-12 T 12-10-2018 AFR_10190 e8af20a4052c2fd3c810bc391c6abd98 284 Gene3D G3DSA:1.10.1740.10 1 75 1.6E-8 T 12-10-2018 AFR_21465 cd7232de3b5dd86228889d904dbced07 147 SMART SM00342 30 113 1.3E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_21465 cd7232de3b5dd86228889d904dbced07 147 SUPERFAMILY SSF46689 66 117 1.39E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21465 cd7232de3b5dd86228889d904dbced07 147 Pfam PF12833 Helix-turn-helix domain 36 114 3.7E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_21465 cd7232de3b5dd86228889d904dbced07 147 SUPERFAMILY SSF46689 14 64 4.93E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21465 cd7232de3b5dd86228889d904dbced07 147 Gene3D G3DSA:1.10.10.60 11 119 6.6E-28 T 12-10-2018 AFR_04415 b4f32fff02d0014ec4c5b249497c2dda 131 Pfam PF01575 MaoC like domain 8 90 1.8E-22 T 12-10-2018 IPR002539 MaoC-like dehydratase domain AFR_04415 b4f32fff02d0014ec4c5b249497c2dda 131 SUPERFAMILY SSF54637 4 124 1.62E-27 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_04415 b4f32fff02d0014ec4c5b249497c2dda 131 Gene3D G3DSA:3.10.129.10 1 130 2.6E-39 T 12-10-2018 AFR_04415 b4f32fff02d0014ec4c5b249497c2dda 131 PRINTS PR01483 Fatty acid synthase signature 36 57 1.6E-5 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AFR_04415 b4f32fff02d0014ec4c5b249497c2dda 131 PRINTS PR01483 Fatty acid synthase signature 14 36 1.6E-5 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AFR_19480 6aacdbc31f07d5a595530f3fb9a82fe5 185 SUPERFAMILY SSF55874 4 154 8.02E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19480 6aacdbc31f07d5a595530f3fb9a82fe5 185 Gene3D G3DSA:3.30.565.10 16 169 3.9E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12105 a37a5092539e9c95ce4325a364510fd7 170 Gene3D G3DSA:3.40.50.10140 2 109 3.8E-19 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_12105 a37a5092539e9c95ce4325a364510fd7 170 SUPERFAMILY SSF52200 4 93 3.14E-14 T 12-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily AFR_12105 a37a5092539e9c95ce4325a364510fd7 170 Pfam PF13676 TIR domain 5 95 2.9E-18 T 12-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 AFR_07955 6f4280b1dc36625c75de6e8a6c4a3c82 353 Pfam PF02562 PhoH-like protein 119 321 2.1E-94 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 AFR_07955 6f4280b1dc36625c75de6e8a6c4a3c82 353 SUPERFAMILY SSF52540 118 284 2.84E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07955 6f4280b1dc36625c75de6e8a6c4a3c82 353 Gene3D G3DSA:3.40.50.300 116 322 3.4E-77 T 12-10-2018 AFR_35900 5d022241a7081a52cf019e2f1620c2dd 300 Gene3D G3DSA:1.20.144.10 188 297 1.5E-10 T 12-10-2018 AFR_35900 5d022241a7081a52cf019e2f1620c2dd 300 Pfam PF14378 PAP2 superfamily 111 278 1.5E-25 T 12-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 AFR_35900 5d022241a7081a52cf019e2f1620c2dd 300 SUPERFAMILY SSF48317 72 292 5.45E-9 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 108 198 5.4E-13 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 Gene3D G3DSA:2.40.110.10 118 208 4.9E-25 T 12-10-2018 AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 Gene3D G3DSA:1.10.540.10 1 96 2.6E-17 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 PIRSF PIRSF016578 1 369 2.4E-37 T 12-10-2018 AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 SUPERFAMILY SSF56645 6 206 2.62E-39 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 SUPERFAMILY SSF47203 225 364 9.83E-28 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 Gene3D G3DSA:1.20.140.10 218 369 4.0E-30 T 12-10-2018 AFR_32765 b355e5b40000b76ac50e60aa810b3563 369 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 227 349 2.7E-19 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFR_10680 47b96bd7fd3310213ed1d9215e2c26de 254 Pfam PF00005 ABC transporter 25 175 1.9E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10680 47b96bd7fd3310213ed1d9215e2c26de 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 247 5.9E-102 T 12-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 AFR_10680 47b96bd7fd3310213ed1d9215e2c26de 254 SMART SM00382 33 227 1.8E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10680 47b96bd7fd3310213ed1d9215e2c26de 254 SUPERFAMILY SSF52540 4 235 3.79E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10680 47b96bd7fd3310213ed1d9215e2c26de 254 Gene3D G3DSA:3.40.50.300 1 249 2.6E-50 T 12-10-2018 AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 Gene3D G3DSA:3.40.50.720 1 297 8.1E-84 T 12-10-2018 AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 SUPERFAMILY SSF51735 9 257 5.43E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_32410 a5c6462c2f120b95f11b69d6f89fa3af 304 Pfam PF00106 short chain dehydrogenase 15 211 1.3E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38955 a73aaadd61219ab10f54c8d3bd6a0907 404 Pfam PF13535 ATP-grasp domain 131 272 2.0E-19 T 12-10-2018 AFR_38955 a73aaadd61219ab10f54c8d3bd6a0907 404 Gene3D G3DSA:3.30.1490.20 127 177 8.1E-11 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_38955 a73aaadd61219ab10f54c8d3bd6a0907 404 Gene3D G3DSA:3.40.50.20 1 120 7.4E-14 T 12-10-2018 AFR_38955 a73aaadd61219ab10f54c8d3bd6a0907 404 Gene3D G3DSA:3.30.470.20 178 389 5.3E-45 T 12-10-2018 AFR_38955 a73aaadd61219ab10f54c8d3bd6a0907 404 SUPERFAMILY SSF56059 103 303 2.53E-39 T 12-10-2018 AFR_38955 a73aaadd61219ab10f54c8d3bd6a0907 404 SUPERFAMILY SSF52440 5 100 1.27E-8 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFR_03750 d3b74dab8916e9ce0d6b7ac76d46de43 573 Pfam PF00005 ABC transporter 361 500 4.8E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_03750 d3b74dab8916e9ce0d6b7ac76d46de43 573 Gene3D G3DSA:1.20.1560.10 6 331 9.7E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_03750 d3b74dab8916e9ce0d6b7ac76d46de43 573 SUPERFAMILY SSF52540 340 570 7.48E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03750 d3b74dab8916e9ce0d6b7ac76d46de43 573 Pfam PF00664 ABC transporter transmembrane region 29 303 5.2E-29 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_03750 d3b74dab8916e9ce0d6b7ac76d46de43 573 Gene3D G3DSA:3.40.50.300 332 570 3.9E-65 T 12-10-2018 AFR_03750 d3b74dab8916e9ce0d6b7ac76d46de43 573 SMART SM00382 370 546 4.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03750 d3b74dab8916e9ce0d6b7ac76d46de43 573 SUPERFAMILY SSF90123 18 332 2.62E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_14730 c67bc5835e5b90ac065f86276e57a6b8 220 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 5 201 2.1E-35 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 AFR_14730 c67bc5835e5b90ac065f86276e57a6b8 220 Gene3D G3DSA:1.10.3630.10 2 214 7.3E-11 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily AFR_38995 e229b679b51d7fa3e9922ddd3a3f8a62 129 Pfam PF00293 NUDIX domain 2 107 3.9E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_38995 e229b679b51d7fa3e9922ddd3a3f8a62 129 SUPERFAMILY SSF55811 1 116 9.75E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_38995 e229b679b51d7fa3e9922ddd3a3f8a62 129 PRINTS PR00502 NUDIX hydrolase family signature 37 52 1.1E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_38995 e229b679b51d7fa3e9922ddd3a3f8a62 129 PRINTS PR00502 NUDIX hydrolase family signature 23 37 1.1E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_38995 e229b679b51d7fa3e9922ddd3a3f8a62 129 Gene3D G3DSA:3.90.79.10 1 118 5.7E-31 T 12-10-2018 AFR_25310 ebf9831fa54ca28b5632ba2a353fe3e2 144 Gene3D G3DSA:3.10.580.10 1 142 3.1E-41 T 12-10-2018 AFR_25310 ebf9831fa54ca28b5632ba2a353fe3e2 144 Pfam PF00571 CBS domain 13 61 4.5E-8 T 12-10-2018 IPR000644 CBS domain AFR_25310 ebf9831fa54ca28b5632ba2a353fe3e2 144 Pfam PF00571 CBS domain 72 124 3.1E-12 T 12-10-2018 IPR000644 CBS domain AFR_25310 ebf9831fa54ca28b5632ba2a353fe3e2 144 SUPERFAMILY SSF54631 1 142 1.77E-31 T 12-10-2018 AFR_25310 ebf9831fa54ca28b5632ba2a353fe3e2 144 SMART SM00116 13 61 3.9E-5 T 12-10-2018 IPR000644 CBS domain AFR_25310 ebf9831fa54ca28b5632ba2a353fe3e2 144 SMART SM00116 79 126 9.5E-9 T 12-10-2018 IPR000644 CBS domain AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 Pfam PF00072 Response regulator receiver domain 7 118 1.1E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 SMART SM00448 5 118 1.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 4.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 SUPERFAMILY SSF46894 150 218 6.46E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 SMART SM00421 156 213 2.0E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 Gene3D G3DSA:3.40.50.12740 5 219 5.1E-66 T 12-10-2018 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 2.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 2.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 2.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21925 d2d9f8209b5707ff25f37c93910de0dd 219 SUPERFAMILY SSF52172 4 136 3.27E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_39530 fe233a81e72511c22f3ab0fcef44ed48 195 Gene3D G3DSA:3.40.50.300 1 189 2.7E-16 T 12-10-2018 AFR_39530 fe233a81e72511c22f3ab0fcef44ed48 195 Pfam PF03029 Conserved hypothetical ATP binding protein 17 184 7.9E-27 T 12-10-2018 IPR004130 GPN-loop GTPase AFR_39530 fe233a81e72511c22f3ab0fcef44ed48 195 SUPERFAMILY SSF52540 13 184 1.14E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_02440 ccaadc83c6670dd14605a7d3f5327f5d 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 314 1.4E-43 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_42840 f2e48b3eb7ff7e4bb145717181061a25 258 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 162 169 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 AFR_42840 f2e48b3eb7ff7e4bb145717181061a25 258 Gene3D G3DSA:3.20.20.150 1 257 6.9E-57 T 12-10-2018 AFR_42840 f2e48b3eb7ff7e4bb145717181061a25 258 SUPERFAMILY SSF51658 1 254 1.57E-57 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_42840 f2e48b3eb7ff7e4bb145717181061a25 258 SMART SM00518 2 256 1.3E-56 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 AFR_42840 f2e48b3eb7ff7e4bb145717181061a25 258 Pfam PF01261 Xylose isomerase-like TIM barrel 13 218 3.7E-28 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_19365 36f2f16620cdba59f8328fc7cd9e1441 134 SUPERFAMILY SSF55729 4 120 5.21E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_19365 36f2f16620cdba59f8328fc7cd9e1441 134 Gene3D G3DSA:3.40.630.30 1 133 1.0E-17 T 12-10-2018 AFR_19365 36f2f16620cdba59f8328fc7cd9e1441 134 Pfam PF13302 Acetyltransferase (GNAT) domain 49 116 8.5E-11 T 12-10-2018 IPR000182 GNAT domain AFR_18330 f555df6c80d6ab69a6193205fb7826e5 249 SUPERFAMILY SSF52540 17 236 2.2E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18330 f555df6c80d6ab69a6193205fb7826e5 249 SMART SM00382 30 217 4.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18330 f555df6c80d6ab69a6193205fb7826e5 249 Gene3D G3DSA:3.40.50.300 3 239 1.6E-58 T 12-10-2018 AFR_18330 f555df6c80d6ab69a6193205fb7826e5 249 Pfam PF00005 ABC transporter 22 166 4.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_23515 625e8bbf9b7b312af6c4865c79ce04d7 147 SUPERFAMILY SSF55961 13 138 6.68E-28 T 12-10-2018 AFR_23515 625e8bbf9b7b312af6c4865c79ce04d7 147 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 130 6.0E-13 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_23515 625e8bbf9b7b312af6c4865c79ce04d7 147 Gene3D G3DSA:3.30.530.20 1 146 6.0E-40 T 12-10-2018 IPR023393 START-like domain superfamily AFR_12435 6b6c7cc147f6c613cf7ea50568cee3e9 424 SUPERFAMILY SSF55874 325 419 6.34E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12435 6b6c7cc147f6c613cf7ea50568cee3e9 424 Gene3D G3DSA:3.30.565.10 293 419 1.5E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12435 6b6c7cc147f6c613cf7ea50568cee3e9 424 Pfam PF07730 Histidine kinase 210 275 2.3E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_30285 d5e19faef4ab7f96985094cf0165aea9 197 SUPERFAMILY SSF46689 8 82 7.28E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_30285 d5e19faef4ab7f96985094cf0165aea9 197 Gene3D G3DSA:1.10.357.10 57 195 1.2E-28 T 12-10-2018 AFR_30285 d5e19faef4ab7f96985094cf0165aea9 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 62 1.1E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_30285 d5e19faef4ab7f96985094cf0165aea9 197 Gene3D G3DSA:1.10.10.60 6 55 1.3E-18 T 12-10-2018 AFR_30285 d5e19faef4ab7f96985094cf0165aea9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.4E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_30285 d5e19faef4ab7f96985094cf0165aea9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.4E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36605 7de1d768f7efd7fcd0a6db298a7efed7 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.6E-12 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_36605 7de1d768f7efd7fcd0a6db298a7efed7 77 Gene3D G3DSA:3.30.70.920 3 76 6.8E-20 T 12-10-2018 AFR_36605 7de1d768f7efd7fcd0a6db298a7efed7 77 SUPERFAMILY SSF54909 2 75 4.16E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_15510 945d4779516d128e55157ca16c4201e8 312 Gene3D G3DSA:3.20.20.30 18 303 3.5E-65 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_15510 945d4779516d128e55157ca16c4201e8 312 SUPERFAMILY SSF51679 3 311 4.06E-69 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_15510 945d4779516d128e55157ca16c4201e8 312 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 19 234 2.3E-85 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c AFR_15510 945d4779516d128e55157ca16c4201e8 312 Pfam PF00296 Luciferase-like monooxygenase 4 253 1.2E-49 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 Pfam PF14561 Tetratricopeptide repeat 6 54 1.2E-5 T 12-10-2018 AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 SUPERFAMILY SSF52540 114 365 8.91E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 Gene3D G3DSA:1.10.8.60 286 360 5.8E-82 T 12-10-2018 AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 Gene3D G3DSA:3.40.50.300 114 365 5.8E-82 T 12-10-2018 AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 SMART SM00382 150 287 3.8E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 SUPERFAMILY SSF48452 7 64 9.49E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 Gene3D G3DSA:1.25.40.10 3 73 7.4E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 154 281 1.2E-42 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_20200 7000c6a208dd8983ef7dbbfcd031cc35 397 ProSitePatterns PS00674 AAA-protein family signature. 255 273 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFR_42460 c0ef594f866f44bd43e391287e2fd9fb 545 Pfam PF00474 Sodium:solute symporter family 279 475 1.3E-17 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFR_42460 c0ef594f866f44bd43e391287e2fd9fb 545 Pfam PF00474 Sodium:solute symporter family 33 198 8.9E-25 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFR_42460 c0ef594f866f44bd43e391287e2fd9fb 545 Gene3D G3DSA:1.20.1730.10 22 230 1.9E-27 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily AFR_42460 c0ef594f866f44bd43e391287e2fd9fb 545 Gene3D G3DSA:1.20.1730.10 243 538 1.3E-20 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily AFR_33900 da1baf7555b53531859f96a9ce79197a 313 Gene3D G3DSA:3.20.20.30 23 310 7.6E-68 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_33900 da1baf7555b53531859f96a9ce79197a 313 Pfam PF00296 Luciferase-like monooxygenase 34 248 1.7E-57 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_33900 da1baf7555b53531859f96a9ce79197a 313 SUPERFAMILY SSF51679 30 281 6.02E-67 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_33900 da1baf7555b53531859f96a9ce79197a 313 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 34 280 1.5E-64 T 12-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted AFR_08110 3fab19567182924b1f066b492b1b5c08 459 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 233 8.3E-81 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 Gene3D G3DSA:3.40.50.800 363 457 4.4E-33 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFR_08110 3fab19567182924b1f066b492b1b5c08 459 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 156 332 1.4E-9 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 457 48.947 T 12-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 2.2E-52 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 316 328 2.2E-52 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 157 174 2.2E-52 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 206 216 2.2E-52 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 402 421 2.2E-52 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 136 148 2.2E-52 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 PRINTS PR01043 Glycyl-tRNA synthetase signature 189 206 2.2E-52 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 Pfam PF03129 Anticodon binding domain 365 454 9.2E-23 T 12-10-2018 IPR004154 Anticodon-binding AFR_08110 3fab19567182924b1f066b492b1b5c08 459 SUPERFAMILY SSF55681 5 368 4.19E-118 T 12-10-2018 AFR_08110 3fab19567182924b1f066b492b1b5c08 459 SUPERFAMILY SSF52954 352 457 1.06E-34 T 12-10-2018 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 SMART SM00354 9 79 4.2E-21 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 SUPERFAMILY SSF47413 9 67 1.62E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 Gene3D G3DSA:3.40.50.2300 63 321 3.4E-68 T 12-10-2018 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 Gene3D G3DSA:3.40.50.2300 167 304 3.4E-68 T 12-10-2018 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 Pfam PF13377 Periplasmic binding protein-like domain 175 342 4.6E-32 T 12-10-2018 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 Gene3D G3DSA:1.10.260.40 3 62 2.0E-22 T 12-10-2018 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 56 3.3E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_11490 c4e2512f9e1755757e2d643551d65839 347 SUPERFAMILY SSF53822 71 345 5.89E-58 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_27570 8f5aa74f88113b53d9a9de8cd192cf28 277 Gene3D G3DSA:1.10.3720.10 62 265 4.9E-19 T 12-10-2018 IPR035906 MetI-like superfamily AFR_27570 8f5aa74f88113b53d9a9de8cd192cf28 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 260 1.2E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_27570 8f5aa74f88113b53d9a9de8cd192cf28 277 SUPERFAMILY SSF161098 65 253 1.57E-17 T 12-10-2018 IPR035906 MetI-like superfamily AFR_39495 9b0c5000a9dcc430caba881fc0e9e410 210 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 205 2.1E-68 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 AFR_39495 9b0c5000a9dcc430caba881fc0e9e410 210 SUPERFAMILY SSF53271 3 205 3.28E-61 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_39495 9b0c5000a9dcc430caba881fc0e9e410 210 Gene3D G3DSA:3.40.50.2020 1 206 2.8E-68 T 12-10-2018 AFR_39495 9b0c5000a9dcc430caba881fc0e9e410 210 Pfam PF14681 Uracil phosphoribosyltransferase 5 205 3.6E-59 T 12-10-2018 AFR_03885 9808c95ad410398a051ec689bc35068d 265 SUPERFAMILY SSF55781 74 253 2.75E-45 T 12-10-2018 AFR_03885 9808c95ad410398a051ec689bc35068d 265 Pfam PF09339 IclR helix-turn-helix domain 12 60 1.6E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_03885 9808c95ad410398a051ec689bc35068d 265 Gene3D G3DSA:3.30.450.40 79 257 3.1E-51 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_03885 9808c95ad410398a051ec689bc35068d 265 Gene3D G3DSA:1.10.10.10 3 78 4.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03885 9808c95ad410398a051ec689bc35068d 265 SUPERFAMILY SSF46785 10 82 3.86E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_03885 9808c95ad410398a051ec689bc35068d 265 Pfam PF01614 Bacterial transcriptional regulator 126 251 2.5E-27 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_03885 9808c95ad410398a051ec689bc35068d 265 SMART SM00346 10 98 3.1E-22 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_38645 5224c1918d4393d5a60400b1db1ffc3a 208 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 184 1.1E-13 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_38645 5224c1918d4393d5a60400b1db1ffc3a 208 SUPERFAMILY SSF48150 26 199 1.38E-34 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_38645 5224c1918d4393d5a60400b1db1ffc3a 208 Gene3D G3DSA:1.10.340.30 35 146 7.9E-52 T 12-10-2018 AFR_38645 5224c1918d4393d5a60400b1db1ffc3a 208 Gene3D G3DSA:1.10.1670.40 9 197 7.9E-52 T 12-10-2018 AFR_38645 5224c1918d4393d5a60400b1db1ffc3a 208 SMART SM00478 47 199 9.2E-13 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 Pfam PF12796 Ankyrin repeats (3 copies) 63 146 1.6E-8 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 Gene3D G3DSA:1.25.40.20 46 161 1.7E-15 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 SUPERFAMILY SSF48403 63 259 1.87E-25 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 Gene3D G3DSA:1.25.40.20 162 261 2.9E-12 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 SMART SM00248 119 148 170.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 SMART SM00248 204 233 190.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 SMART SM00248 170 199 760.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_16880 73e4773fd4fce8e53695b038a4e5f29c 261 SMART SM00248 80 109 0.048 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_40090 b51fc830ffe6fa106e92fe904481f211 277 SUPERFAMILY SSF52096 14 277 2.49E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_40090 b51fc830ffe6fa106e92fe904481f211 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 117 137 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFR_40090 b51fc830ffe6fa106e92fe904481f211 277 Gene3D G3DSA:1.10.12.10 220 277 8.3E-17 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFR_40090 b51fc830ffe6fa106e92fe904481f211 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 276 3.8E-52 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_40090 b51fc830ffe6fa106e92fe904481f211 277 Gene3D G3DSA:3.90.226.10 17 219 8.8E-62 T 12-10-2018 AFR_35930 0a814736175d4d89ba485372b889ae14 39 SUPERFAMILY SSF52172 3 38 7.83E-7 T 12-10-2018 IPR011006 CheY-like superfamily AFR_35930 0a814736175d4d89ba485372b889ae14 39 Gene3D G3DSA:3.40.50.12740 2 39 1.6E-6 T 12-10-2018 AFR_15670 4c15f537facae0c6e8ef06d86586fb42 267 Gene3D G3DSA:3.60.15.10 3 246 8.3E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_15670 4c15f537facae0c6e8ef06d86586fb42 267 SMART SM00849 39 241 2.8E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_15670 4c15f537facae0c6e8ef06d86586fb42 267 Pfam PF00753 Metallo-beta-lactamase superfamily 43 203 2.8E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_15670 4c15f537facae0c6e8ef06d86586fb42 267 SUPERFAMILY SSF56281 37 245 1.76E-26 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_23855 61afdc43e3a6b5d2aee725633c1485dd 396 Gene3D G3DSA:1.20.1250.20 6 386 1.8E-27 T 12-10-2018 AFR_23855 61afdc43e3a6b5d2aee725633c1485dd 396 Pfam PF07690 Major Facilitator Superfamily 14 356 2.7E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_23855 61afdc43e3a6b5d2aee725633c1485dd 396 SUPERFAMILY SSF103473 9 393 2.49E-32 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_29780 6fc2c1e295e09a3de773aa1279178750 305 Gene3D G3DSA:1.10.340.30 114 233 6.6E-32 T 12-10-2018 AFR_29780 6fc2c1e295e09a3de773aa1279178750 305 SMART SM00478 126 288 0.0026 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFR_29780 6fc2c1e295e09a3de773aa1279178750 305 SUPERFAMILY SSF48150 105 283 9.11E-30 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_29780 6fc2c1e295e09a3de773aa1279178750 305 Gene3D G3DSA:1.10.1670.40 94 281 6.6E-32 T 12-10-2018 AFR_01535 d87549397681eef8e28153c2b1a17088 246 PIRSF PIRSF006648 1 245 1.7E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_39475 d0ee6b831f2f1541e9accb895f1f6666 227 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 6 187 8.0E-43 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 AFR_39475 d0ee6b831f2f1541e9accb895f1f6666 227 Gene3D G3DSA:1.10.3630.10 1 208 4.2E-27 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily AFR_03150 9745ff516231ec607233cd87451c1e8d 277 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AFR_03150 9745ff516231ec607233cd87451c1e8d 277 Gene3D G3DSA:3.40.50.150 4 186 1.8E-38 T 12-10-2018 AFR_03150 9745ff516231ec607233cd87451c1e8d 277 SMART SM00650 25 185 4.7E-65 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AFR_03150 9745ff516231ec607233cd87451c1e8d 277 SUPERFAMILY SSF53335 10 256 9.71E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_03150 9745ff516231ec607233cd87451c1e8d 277 Pfam PF00398 Ribosomal RNA adenine dimethylase 10 255 4.3E-41 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AFR_36365 a0ea44a0d33afc68622c2d4c1aec6be3 206 Gene3D G3DSA:3.90.1570.10 18 161 8.4E-20 T 12-10-2018 AFR_36365 a0ea44a0d33afc68622c2d4c1aec6be3 206 SUPERFAMILY SSF52980 21 155 1.39E-23 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_36365 a0ea44a0d33afc68622c2d4c1aec6be3 206 Pfam PF05685 Putative restriction endonuclease 27 154 5.7E-25 T 12-10-2018 IPR008538 Domain of unknown function DUF820 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 Pfam PF00561 alpha/beta hydrolase fold 25 263 2.1E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 SUPERFAMILY SSF53474 9 276 3.06E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 1.4E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.4E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.4E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 PRINTS PR00412 Epoxide hydrolase signature 252 274 2.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 PRINTS PR00412 Epoxide hydrolase signature 31 49 2.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 PRINTS PR00412 Epoxide hydrolase signature 51 66 2.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 PRINTS PR00412 Epoxide hydrolase signature 218 234 2.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28970 3b51bfa119c2af7c0808556b15af34ca 281 Gene3D G3DSA:3.40.50.1820 3 276 8.7E-77 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_02190 bfbeced08126c5c6c8f83af7d8ac76ac 393 Gene3D G3DSA:3.40.640.10 19 245 2.3E-72 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_02190 bfbeced08126c5c6c8f83af7d8ac76ac 393 SUPERFAMILY SSF53383 3 339 1.5E-53 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_02190 bfbeced08126c5c6c8f83af7d8ac76ac 393 Gene3D G3DSA:3.90.1150.10 7 337 2.3E-72 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_02190 bfbeced08126c5c6c8f83af7d8ac76ac 393 Pfam PF00155 Aminotransferase class I and II 19 336 1.6E-28 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 Pfam PF00561 alpha/beta hydrolase fold 33 285 6.6E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 1.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 Gene3D G3DSA:3.40.50.1820 12 301 1.9E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 SUPERFAMILY SSF53474 11 301 4.28E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00412 Epoxide hydrolase signature 39 57 1.3E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00412 Epoxide hydrolase signature 277 299 1.3E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.3E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00412 Epoxide hydrolase signature 117 130 1.3E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_01790 236c670ad865ed2d33d90e0a4dd1fc1a 302 PRINTS PR00412 Epoxide hydrolase signature 59 74 1.3E-20 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 238 1.4E-53 T 12-10-2018 AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 Gene3D G3DSA:3.40.50.720 1 241 9.2E-69 T 12-10-2018 AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 1.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 SUPERFAMILY SSF51735 2 238 1.44E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_10700 a21202fe6ed8dcff18f2901a4a947e45 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.9E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_18800 4b0cf95fc64d5e3de81e4f03a2589b1d 245 Gene3D G3DSA:3.40.50.300 5 233 3.9E-57 T 12-10-2018 AFR_18800 4b0cf95fc64d5e3de81e4f03a2589b1d 245 SMART SM00382 32 208 6.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18800 4b0cf95fc64d5e3de81e4f03a2589b1d 245 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_18800 4b0cf95fc64d5e3de81e4f03a2589b1d 245 SUPERFAMILY SSF52540 14 220 3.0E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18800 4b0cf95fc64d5e3de81e4f03a2589b1d 245 Pfam PF00005 ABC transporter 23 161 3.1E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04800 a54ac8bc64f7d4a7e8670f95fc172046 395 Gene3D G3DSA:3.40.640.10 47 291 1.5E-139 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_04800 a54ac8bc64f7d4a7e8670f95fc172046 395 Pfam PF00155 Aminotransferase class I and II 35 391 5.7E-61 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_04800 a54ac8bc64f7d4a7e8670f95fc172046 395 SUPERFAMILY SSF53383 13 393 1.48E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_04800 a54ac8bc64f7d4a7e8670f95fc172046 395 Gene3D G3DSA:3.90.1150.10 24 391 1.5E-139 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_37090 ef90c32add7acc7a8e3807595eb3fc2f 273 Gene3D G3DSA:3.40.50.300 3 271 1.4E-57 T 12-10-2018 AFR_37090 ef90c32add7acc7a8e3807595eb3fc2f 273 SMART SM00382 42 239 5.4E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_37090 ef90c32add7acc7a8e3807595eb3fc2f 273 SUPERFAMILY SSF52540 10 250 1.11E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37090 ef90c32add7acc7a8e3807595eb3fc2f 273 Pfam PF00005 ABC transporter 33 185 7.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_39075 235136e01fc1508155b2842aae79c63b 192 Gene3D G3DSA:1.20.144.10 125 192 7.4E-6 T 12-10-2018 AFR_39075 235136e01fc1508155b2842aae79c63b 192 SUPERFAMILY SSF48317 103 188 3.6E-6 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_02590 86d9e73726def39d2c886e01f6e00b4f 207 Gene3D G3DSA:3.40.50.12740 4 207 1.3E-25 T 12-10-2018 AFR_02590 86d9e73726def39d2c886e01f6e00b4f 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 3.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02590 86d9e73726def39d2c886e01f6e00b4f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02590 86d9e73726def39d2c886e01f6e00b4f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02590 86d9e73726def39d2c886e01f6e00b4f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02590 86d9e73726def39d2c886e01f6e00b4f 207 SUPERFAMILY SSF46894 134 207 6.8E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_02590 86d9e73726def39d2c886e01f6e00b4f 207 SMART SM00421 144 201 5.7E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_02695 42c1fc73c258f54c7b3304a3cdef6d6f 81 SUPERFAMILY SSF47336 5 73 7.59E-11 T 12-10-2018 IPR036736 ACP-like superfamily AFR_02695 42c1fc73c258f54c7b3304a3cdef6d6f 81 Gene3D G3DSA:1.10.1200.10 3 76 6.5E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFR_02695 42c1fc73c258f54c7b3304a3cdef6d6f 81 Pfam PF00550 Phosphopantetheine attachment site 5 67 1.8E-6 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_02070 6cfe0a02690f6031e569cefcec881ecb 113 Gene3D G3DSA:1.10.10.10 3 111 1.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02070 6cfe0a02690f6031e569cefcec881ecb 113 SUPERFAMILY SSF46785 16 108 4.27E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_02070 6cfe0a02690f6031e569cefcec881ecb 113 Pfam PF03551 Transcriptional regulator PadR-like family 20 91 1.2E-20 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_13640 33986b6350525bb5e4f3a2ac99068571 533 Pfam PF00999 Sodium/hydrogen exchanger family 12 408 3.8E-56 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_13640 33986b6350525bb5e4f3a2ac99068571 533 Gene3D G3DSA:1.20.1530.20 5 329 6.2E-11 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFR_13640 33986b6350525bb5e4f3a2ac99068571 533 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 10 526 5.3E-119 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 AFR_21330 58aeb7dce6844c65f9dee3c6b8803eaa 195 SUPERFAMILY SSF48498 88 190 1.85E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_21330 58aeb7dce6844c65f9dee3c6b8803eaa 195 Gene3D G3DSA:1.10.10.60 10 59 5.7E-19 T 12-10-2018 AFR_21330 58aeb7dce6844c65f9dee3c6b8803eaa 195 SUPERFAMILY SSF46689 17 82 8.72E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21330 58aeb7dce6844c65f9dee3c6b8803eaa 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 58 2.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_21330 58aeb7dce6844c65f9dee3c6b8803eaa 195 Gene3D G3DSA:1.10.357.10 60 191 1.1E-26 T 12-10-2018 AFR_21330 58aeb7dce6844c65f9dee3c6b8803eaa 195 Pfam PF13305 WHG domain 94 167 2.3E-6 T 12-10-2018 IPR025996 WHG domain AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 SUPERFAMILY SSF51110 78 141 5.76E-16 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 SUPERFAMILY SSF53955 155 240 3.94E-17 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 SMART SM00108 27 138 4.6E-19 T 12-10-2018 IPR001480 Bulb-type lectin domain AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 Gene3D G3DSA:2.90.10.10 15 81 1.0E-17 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 Gene3D G3DSA:1.10.530.10 151 208 1.9E-7 T 12-10-2018 AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 Pfam PF01464 Transglycosylase SLT domain 166 243 2.4E-8 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 Pfam PF01453 D-mannose binding lectin 46 100 9.3E-11 T 12-10-2018 IPR001480 Bulb-type lectin domain AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 SUPERFAMILY SSF51110 29 98 2.88E-15 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_16195 3e6a513a0dca31a05fad091c217c895a 258 Gene3D G3DSA:2.90.10.10 82 150 4.5E-19 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 Gene3D G3DSA:3.30.200.20 1 90 3.8E-26 T 12-10-2018 AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 PIRSF PIRSF000654 13 267 1.2E-19 T 12-10-2018 AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 SMART SM00220 8 271 8.6E-58 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 Pfam PF00069 Protein kinase domain 8 260 7.5E-47 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 SUPERFAMILY SSF56112 5 262 1.97E-69 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_24975 a7e0fe60ac8f1b6e0581ccf3a2b81b86 329 Gene3D G3DSA:1.10.510.10 91 301 5.3E-47 T 12-10-2018 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 SUPERFAMILY SSF81442 26 535 1.96E-172 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 1.4E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 7.2E-212 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 480 9.2E-150 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_14270 08a05d43abe5fb25c8e8242666c6a557 585 Gene3D G3DSA:1.20.210.10 16 541 3.2E-203 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_06160 ba1f7b8e0e88d1b199dc18d49d2f128b 245 SUPERFAMILY SSF46689 21 83 9.71E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06160 ba1f7b8e0e88d1b199dc18d49d2f128b 245 SUPERFAMILY SSF48498 95 240 2.0E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_06160 ba1f7b8e0e88d1b199dc18d49d2f128b 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 77 6.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_06160 ba1f7b8e0e88d1b199dc18d49d2f128b 245 Gene3D G3DSA:1.10.357.10 84 240 5.0E-39 T 12-10-2018 AFR_06160 ba1f7b8e0e88d1b199dc18d49d2f128b 245 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 90 235 4.3E-20 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_06160 ba1f7b8e0e88d1b199dc18d49d2f128b 245 Gene3D G3DSA:1.10.10.60 8 82 3.0E-25 T 12-10-2018 AFR_14970 ee6574acad432d8c6767aa1a00561e12 447 Gene3D G3DSA:3.20.20.80 58 221 1.5E-10 T 12-10-2018 AFR_14970 ee6574acad432d8c6767aa1a00561e12 447 Pfam PF16116 Domain of unknown function (DUF4832) 263 429 3.3E-9 T 12-10-2018 IPR032267 Domain of unknown function DUF4832 AFR_14970 ee6574acad432d8c6767aa1a00561e12 447 SUPERFAMILY SSF51445 60 179 2.51E-6 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_04720 2febd1bedb9993b4ed76d0a52558e4c1 522 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 71 497 97.089 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFR_04720 2febd1bedb9993b4ed76d0a52558e4c1 522 Pfam PF01964 Radical SAM ThiC family 72 493 7.7E-201 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFR_04720 2febd1bedb9993b4ed76d0a52558e4c1 522 Pfam PF13667 ThiC-associated domain 1 56 7.3E-12 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFR_04720 2febd1bedb9993b4ed76d0a52558e4c1 522 Gene3D G3DSA:3.20.20.540 116 428 1.0E-150 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFR_04720 2febd1bedb9993b4ed76d0a52558e4c1 522 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 72 495 5.4E-210 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFR_03200 ada31824c7e0de746d8d9c9d30c08d61 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 146 5.1E-25 T 12-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AFR_03200 ada31824c7e0de746d8d9c9d30c08d61 167 SUPERFAMILY SSF56300 1 162 9.87E-32 T 12-10-2018 AFR_03200 ada31824c7e0de746d8d9c9d30c08d61 167 Gene3D G3DSA:3.60.21.10 1 158 3.6E-35 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_03200 ada31824c7e0de746d8d9c9d30c08d61 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 145 1.6E-24 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFR_28835 ad3fab02509e3422bbded18c989d5e90 125 SUPERFAMILY SSF46955 4 103 1.1E-21 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_28835 ad3fab02509e3422bbded18c989d5e90 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.2E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_28835 ad3fab02509e3422bbded18c989d5e90 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.2E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_28835 ad3fab02509e3422bbded18c989d5e90 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.2E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_28835 ad3fab02509e3422bbded18c989d5e90 125 Gene3D G3DSA:1.10.1660.10 6 125 7.6E-28 T 12-10-2018 AFR_28835 ad3fab02509e3422bbded18c989d5e90 125 SMART SM00422 3 72 1.1E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_28835 ad3fab02509e3422bbded18c989d5e90 125 Pfam PF13411 MerR HTH family regulatory protein 4 67 1.1E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_03915 02eb45fc64dfa44bb2f8313597190106 99 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 4.4E-21 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 AFR_22510 03d44e93689ce417e41a8b01925cf62f 178 Pfam PF13671 AAA domain 8 142 5.6E-19 T 12-10-2018 AFR_22510 03d44e93689ce417e41a8b01925cf62f 178 SUPERFAMILY SSF52540 1 144 1.84E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22510 03d44e93689ce417e41a8b01925cf62f 178 Gene3D G3DSA:3.40.50.300 1 152 6.4E-23 T 12-10-2018 AFR_34805 f7ea3bb0e91540c422d49b73fe7ea79c 356 SUPERFAMILY SSF51735 1 318 3.64E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_34805 f7ea3bb0e91540c422d49b73fe7ea79c 356 Gene3D G3DSA:3.40.50.720 1 322 7.2E-44 T 12-10-2018 AFR_34805 f7ea3bb0e91540c422d49b73fe7ea79c 356 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 236 5.6E-19 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_25240 1ffcd3ac7ef29325274154c744ef8009 168 Gene3D G3DSA:3.40.50.300 4 166 1.4E-13 T 12-10-2018 AFR_25240 1ffcd3ac7ef29325274154c744ef8009 168 Pfam PF13238 AAA domain 7 116 4.4E-9 T 12-10-2018 AFR_25240 1ffcd3ac7ef29325274154c744ef8009 168 SUPERFAMILY SSF52540 5 160 1.01E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21325 356525a93a48c2785354031f3a65e564 276 Gene3D G3DSA:3.40.50.1820 1 272 3.2E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21325 356525a93a48c2785354031f3a65e564 276 PRINTS PR00412 Epoxide hydrolase signature 248 270 6.7E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21325 356525a93a48c2785354031f3a65e564 276 PRINTS PR00412 Epoxide hydrolase signature 27 45 6.7E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21325 356525a93a48c2785354031f3a65e564 276 PRINTS PR00412 Epoxide hydrolase signature 104 117 6.7E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21325 356525a93a48c2785354031f3a65e564 276 PRINTS PR00412 Epoxide hydrolase signature 47 62 6.7E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_21325 356525a93a48c2785354031f3a65e564 276 SUPERFAMILY SSF53474 3 272 9.16E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21325 356525a93a48c2785354031f3a65e564 276 Pfam PF00561 alpha/beta hydrolase fold 21 258 7.9E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28635 3818e7cfba82d3412bb63d374254fe8a 324 Gene3D G3DSA:3.90.550.10 4 187 7.9E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_28635 3818e7cfba82d3412bb63d374254fe8a 324 Pfam PF00535 Glycosyl transferase family 2 10 173 7.3E-29 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_28635 3818e7cfba82d3412bb63d374254fe8a 324 SUPERFAMILY SSF53448 6 213 2.34E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_37030 c6481426ec79fbeb57ffeaeefbb0242d 259 SUPERFAMILY SSF52402 1 254 2.45E-73 T 12-10-2018 AFR_37030 c6481426ec79fbeb57ffeaeefbb0242d 259 Pfam PF01012 Electron transfer flavoprotein domain 24 207 9.6E-50 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFR_37030 c6481426ec79fbeb57ffeaeefbb0242d 259 PIRSF PIRSF000090 1 259 5.8E-81 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFR_37030 c6481426ec79fbeb57ffeaeefbb0242d 259 Gene3D G3DSA:3.40.50.620 1 259 2.0E-83 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_37030 c6481426ec79fbeb57ffeaeefbb0242d 259 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 156 176 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFR_37030 c6481426ec79fbeb57ffeaeefbb0242d 259 SMART SM00893 23 212 1.6E-58 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFR_14355 cd3887b54bdd86f15571a8307b4b0e6d 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 278 2.2E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_14355 cd3887b54bdd86f15571a8307b4b0e6d 290 Gene3D G3DSA:1.10.3720.10 48 288 6.5E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14355 cd3887b54bdd86f15571a8307b4b0e6d 290 SUPERFAMILY SSF161098 52 277 3.92E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_16250 f9b1fa4423d62598605b9fbaf7ab05c4 640 Gene3D G3DSA:3.30.565.10 517 639 8.7E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_16250 f9b1fa4423d62598605b9fbaf7ab05c4 640 SUPERFAMILY SSF55781 371 444 1.4E-7 T 12-10-2018 AFR_16250 f9b1fa4423d62598605b9fbaf7ab05c4 640 SUPERFAMILY SSF55874 537 638 8.88E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_16250 f9b1fa4423d62598605b9fbaf7ab05c4 640 Gene3D G3DSA:3.30.450.40 285 449 1.2E-6 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_16250 f9b1fa4423d62598605b9fbaf7ab05c4 640 Pfam PF07730 Histidine kinase 452 519 2.4E-9 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_24715 b88e465de446a2135d350ae5b7642b94 404 Gene3D G3DSA:2.130.10.10 248 404 9.7E-21 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_24715 b88e465de446a2135d350ae5b7642b94 404 SUPERFAMILY SSF50974 273 388 9.42E-20 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 AFR_32910 d30aff1b25da84cacb795e0e10d0179e 209 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 AFR_32910 d30aff1b25da84cacb795e0e10d0179e 209 SUPERFAMILY SSF51569 4 198 1.19E-51 T 12-10-2018 AFR_32910 d30aff1b25da84cacb795e0e10d0179e 209 Gene3D G3DSA:3.20.20.70 1 208 2.4E-59 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_32910 d30aff1b25da84cacb795e0e10d0179e 209 Pfam PF01081 KDPG and KHG aldolase 10 181 3.5E-33 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 279 1.5E-26 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 Gene3D G3DSA:3.50.50.60 1 285 9.0E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 131 2.8E-7 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 255 273 2.8E-7 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 97 105 2.8E-7 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 134 158 2.8E-7 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 SUPERFAMILY SSF51905 1 289 2.47E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 20 3.9E-16 T 12-10-2018 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 267 3.9E-16 T 12-10-2018 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 3.9E-16 T 12-10-2018 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.9E-16 T 12-10-2018 AFR_08855 df837e673a65dfdd0fe8299fc9dc02fd 308 Gene3D G3DSA:3.50.50.60 110 221 9.0E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_03390 04019fa31c21ffbef760559c0621c6ff 166 Gene3D G3DSA:3.40.50.150 3 157 8.3E-16 T 12-10-2018 AFR_03390 04019fa31c21ffbef760559c0621c6ff 166 Pfam PF13649 Methyltransferase domain 22 117 1.1E-6 T 12-10-2018 AFR_03390 04019fa31c21ffbef760559c0621c6ff 166 SUPERFAMILY SSF53335 7 154 2.24E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_21030 2621548a1f2d20cfe996c61fe0722d78 299 Gene3D G3DSA:3.90.660.10 41 259 7.4E-65 T 12-10-2018 AFR_21030 2621548a1f2d20cfe996c61fe0722d78 299 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.8E-7 T 12-10-2018 AFR_21030 2621548a1f2d20cfe996c61fe0722d78 299 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 264 279 1.8E-7 T 12-10-2018 AFR_21030 2621548a1f2d20cfe996c61fe0722d78 299 SUPERFAMILY SSF51905 1 295 1.14E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_21030 2621548a1f2d20cfe996c61fe0722d78 299 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 65 1.7E-14 T 12-10-2018 AFR_21030 2621548a1f2d20cfe996c61fe0722d78 299 Pfam PF01593 Flavin containing amine oxidoreductase 111 294 8.5E-7 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_21030 2621548a1f2d20cfe996c61fe0722d78 299 Gene3D G3DSA:3.50.50.60 3 291 7.4E-65 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_21090 ea7f8b7bc4c098c0757bbc250c64dd4c 250 SUPERFAMILY SSF46955 38 113 1.79E-13 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_21090 ea7f8b7bc4c098c0757bbc250c64dd4c 250 Pfam PF00376 MerR family regulatory protein 26 67 6.7E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21090 ea7f8b7bc4c098c0757bbc250c64dd4c 250 Gene3D G3DSA:1.10.1660.10 40 155 9.1E-18 T 12-10-2018 AFR_21090 ea7f8b7bc4c098c0757bbc250c64dd4c 250 SMART SM00422 25 99 2.5E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_19240 6a1b0fad6ebcbadf2b89043e5c73d18f 101 Gene3D G3DSA:3.30.750.24 4 101 4.3E-17 T 12-10-2018 IPR036513 STAS domain superfamily AFR_19240 6a1b0fad6ebcbadf2b89043e5c73d18f 101 SUPERFAMILY SSF52091 10 99 1.96E-13 T 12-10-2018 IPR036513 STAS domain superfamily AFR_19240 6a1b0fad6ebcbadf2b89043e5c73d18f 101 Pfam PF13466 STAS domain 12 92 1.0E-11 T 12-10-2018 IPR002645 STAS domain AFR_35890 0ed1c687a97096812478766974151593 673 SUPERFAMILY SSF48208 208 661 1.4E-60 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_35890 0ed1c687a97096812478766974151593 673 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 18 192 1.9E-25 T 12-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal AFR_35890 0ed1c687a97096812478766974151593 673 Gene3D G3DSA:1.50.10.10 241 615 2.0E-33 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_39705 02526e57bd8414cb108ec34e223e6502 599 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 151 599 8.9E-126 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AFR_39705 02526e57bd8414cb108ec34e223e6502 599 Pfam PF02397 Bacterial sugar transferase 406 593 6.2E-65 T 12-10-2018 IPR003362 Bacterial sugar transferase AFR_36445 c3c57207ad7e2b17f533da626356541f 173 Gene3D G3DSA:1.20.120.450 3 172 7.4E-34 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_36445 c3c57207ad7e2b17f533da626356541f 173 SUPERFAMILY SSF109854 3 168 4.12E-43 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_36445 c3c57207ad7e2b17f533da626356541f 173 Pfam PF04978 Protein of unknown function (DUF664) 24 169 6.6E-45 T 12-10-2018 IPR007061 Protein of unknown function DUF664 AFR_32225 2ca32945cb881830a38335a89bd8b332 394 Pfam PF05762 VWA domain containing CoxE-like protein 155 370 1.1E-54 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like AFR_32225 2ca32945cb881830a38335a89bd8b332 394 Gene3D G3DSA:3.40.50.410 209 372 2.1E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_32225 2ca32945cb881830a38335a89bd8b332 394 SUPERFAMILY SSF53300 214 376 8.11E-25 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_32225 2ca32945cb881830a38335a89bd8b332 394 SMART SM00327 214 373 5.3E-5 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_26645 ba08c78706d8f8d6a7503102cdded473 230 SUPERFAMILY SSF53254 3 206 1.77E-46 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_26645 ba08c78706d8f8d6a7503102cdded473 230 SMART SM00855 3 158 5.0E-22 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_26645 ba08c78706d8f8d6a7503102cdded473 230 Gene3D G3DSA:3.40.50.1240 1 206 9.1E-47 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_26645 ba08c78706d8f8d6a7503102cdded473 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 198 7.7E-49 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_26645 ba08c78706d8f8d6a7503102cdded473 230 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 200 5.2E-92 T 12-10-2018 IPR022492 Phosphomutase MSMEG4193, putative AFR_35790 a30257ec25b39120767c8288df548a80 288 Pfam PF04012 PspA/IM30 family 3 242 7.7E-48 T 12-10-2018 IPR007157 PspA/IM30 AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 179 4.1E-44 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 SUPERFAMILY SSF47807 182 296 1.64E-20 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 SMART SM00475 4 273 1.2E-76 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 SMART SM00279 182 217 7.1E-10 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 SUPERFAMILY SSF88723 4 158 3.34E-38 T 12-10-2018 IPR029060 PIN-like domain superfamily AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 Gene3D G3DSA:1.10.150.20 183 259 4.3E-65 T 12-10-2018 AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 Gene3D G3DSA:3.40.50.1010 7 287 4.3E-65 T 12-10-2018 AFR_21865 9b3985d5ee7c8f3ae7e60bd6fb2f27b0 303 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 181 268 1.5E-18 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 AFR_12355 de6851fdf655c773df63d8c915231784 373 SUPERFAMILY SSF53474 2 366 4.76E-101 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12355 de6851fdf655c773df63d8c915231784 373 PRINTS PR00412 Epoxide hydrolase signature 346 368 9.0E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12355 de6851fdf655c773df63d8c915231784 373 PRINTS PR00412 Epoxide hydrolase signature 314 330 9.0E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12355 de6851fdf655c773df63d8c915231784 373 PRINTS PR00412 Epoxide hydrolase signature 98 116 9.0E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12355 de6851fdf655c773df63d8c915231784 373 PRINTS PR00412 Epoxide hydrolase signature 172 185 9.0E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12355 de6851fdf655c773df63d8c915231784 373 PRINTS PR00412 Epoxide hydrolase signature 127 142 9.0E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_12355 de6851fdf655c773df63d8c915231784 373 PIRSF PIRSF001112 1 373 9.3E-135 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_12355 de6851fdf655c773df63d8c915231784 373 Pfam PF06441 Epoxide hydrolase N terminus 4 107 1.3E-33 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_12355 de6851fdf655c773df63d8c915231784 373 Gene3D G3DSA:3.40.50.1820 4 373 3.4E-140 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_26870 bd004d95136070a55c650f94b1753bd0 122 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 5 119 1.9E-35 T 12-10-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative AFR_26870 bd004d95136070a55c650f94b1753bd0 122 SUPERFAMILY SSF50475 6 99 9.74E-18 T 12-10-2018 AFR_26870 bd004d95136070a55c650f94b1753bd0 122 Gene3D G3DSA:2.30.110.10 4 122 6.4E-19 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_26870 bd004d95136070a55c650f94b1753bd0 122 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 67 8.4E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_14650 e285d88728d66eb466bbd9952103cdfe 327 Pfam PF14525 AraC-binding-like domain 25 198 6.4E-18 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFR_14650 e285d88728d66eb466bbd9952103cdfe 327 Gene3D G3DSA:1.10.10.60 222 327 1.9E-36 T 12-10-2018 AFR_14650 e285d88728d66eb466bbd9952103cdfe 327 SUPERFAMILY SSF46689 224 272 1.84E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14650 e285d88728d66eb466bbd9952103cdfe 327 SMART SM00342 238 325 6.1E-29 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14650 e285d88728d66eb466bbd9952103cdfe 327 Pfam PF12833 Helix-turn-helix domain 244 326 3.4E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14650 e285d88728d66eb466bbd9952103cdfe 327 SUPERFAMILY SSF46689 274 324 7.99E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_27025 06fa1aea7b110a18ecd1b637bc2fc35b 121 SUPERFAMILY SSF52172 2 117 2.13E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_27025 06fa1aea7b110a18ecd1b637bc2fc35b 121 Pfam PF00072 Response regulator receiver domain 2 112 1.1E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_27025 06fa1aea7b110a18ecd1b637bc2fc35b 121 SMART SM00448 1 112 2.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_27025 06fa1aea7b110a18ecd1b637bc2fc35b 121 Gene3D G3DSA:3.40.50.12740 1 121 5.1E-37 T 12-10-2018 AFR_26225 821373592e663fac54f9805cc128aa66 320 Gene3D G3DSA:3.40.190.10 84 304 2.2E-65 T 12-10-2018 AFR_26225 821373592e663fac54f9805cc128aa66 320 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 107 120 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site AFR_26225 821373592e663fac54f9805cc128aa66 320 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 84 305 1.1E-41 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_26225 821373592e663fac54f9805cc128aa66 320 Gene3D G3DSA:3.40.190.10 171 269 2.2E-65 T 12-10-2018 AFR_26225 821373592e663fac54f9805cc128aa66 320 SUPERFAMILY SSF53850 73 306 2.28E-48 T 12-10-2018 AFR_26225 821373592e663fac54f9805cc128aa66 320 SMART SM00062 83 307 5.1E-48 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_01835 c7f77db2b3096f665b0ac78326bc86db 118 Gene3D G3DSA:3.30.750.24 6 116 6.7E-24 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01835 c7f77db2b3096f665b0ac78326bc86db 118 SUPERFAMILY SSF52091 11 105 7.65E-19 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01835 c7f77db2b3096f665b0ac78326bc86db 118 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 106 5.0E-17 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_01835 c7f77db2b3096f665b0ac78326bc86db 118 Pfam PF13466 STAS domain 19 97 6.4E-13 T 12-10-2018 IPR002645 STAS domain AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 Gene3D G3DSA:3.40.50.720 2 259 7.3E-59 T 12-10-2018 AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 SUPERFAMILY SSF51735 3 234 9.39E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 Pfam PF00106 short chain dehydrogenase 3 191 8.5E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 3.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31330 e9c0f479fce482e24a3c6711cdbb094d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 Gene3D G3DSA:1.10.10.10 111 203 1.2E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 Pfam PF08281 Sigma-70, region 4 143 196 6.2E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 Pfam PF04542 Sigma-70 region 2 45 112 2.1E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 67 99 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 SUPERFAMILY SSF88946 23 117 2.75E-24 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 Gene3D G3DSA:1.10.1740.10 26 110 5.9E-34 T 12-10-2018 AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 200 2.2E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_37735 1958e3d3627c9ca52004f9493b8bdb8a 206 SUPERFAMILY SSF88659 137 200 3.49E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_23545 e2b8a55461e578499783c81ce81cfbb8 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23545 e2b8a55461e578499783c81ce81cfbb8 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23545 e2b8a55461e578499783c81ce81cfbb8 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23545 e2b8a55461e578499783c81ce81cfbb8 199 Gene3D G3DSA:1.10.357.10 5 197 1.1E-33 T 12-10-2018 AFR_23545 e2b8a55461e578499783c81ce81cfbb8 199 SUPERFAMILY SSF46689 7 80 8.72E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14190 0f3aecfb458e98c2b932b26750a86aa8 215 Gene3D G3DSA:2.30.110.10 29 157 4.2E-24 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_14190 0f3aecfb458e98c2b932b26750a86aa8 215 SUPERFAMILY SSF50475 32 183 1.13E-14 T 12-10-2018 AFR_14190 0f3aecfb458e98c2b932b26750a86aa8 215 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 18 201 1.5E-62 T 12-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent AFR_14190 0f3aecfb458e98c2b932b26750a86aa8 215 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 132 1.4E-12 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_19045 8da7f2c94f8296f0d543ecb8d9e5af71 168 Pfam PF01799 [2Fe-2S] binding domain 71 159 7.4E-29 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFR_19045 8da7f2c94f8296f0d543ecb8d9e5af71 168 SUPERFAMILY SSF47741 82 162 5.1E-26 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily AFR_19045 8da7f2c94f8296f0d543ecb8d9e5af71 168 Gene3D G3DSA:1.10.150.120 75 164 2.2E-32 T 12-10-2018 AFR_19045 8da7f2c94f8296f0d543ecb8d9e5af71 168 SUPERFAMILY SSF54292 4 85 9.83E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_19045 8da7f2c94f8296f0d543ecb8d9e5af71 168 Gene3D G3DSA:3.10.20.30 1 74 1.5E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_19045 8da7f2c94f8296f0d543ecb8d9e5af71 168 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_19045 8da7f2c94f8296f0d543ecb8d9e5af71 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 3 61 9.8E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_29005 bf581c3bc3d6a188ae47cc5e4d600ad4 267 Pfam PF08241 Methyltransferase domain 40 139 2.4E-19 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_29005 bf581c3bc3d6a188ae47cc5e4d600ad4 267 SUPERFAMILY SSF53335 2 218 3.53E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_29005 bf581c3bc3d6a188ae47cc5e4d600ad4 267 Gene3D G3DSA:3.40.50.150 1 258 2.1E-40 T 12-10-2018 AFR_36205 e68fb4a1fa1dcd6f018e7c034962fd88 185 SUPERFAMILY SSF55194 3 184 6.93E-65 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 AFR_36205 e68fb4a1fa1dcd6f018e7c034962fd88 185 Pfam PF01765 Ribosome recycling factor 21 183 1.3E-57 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AFR_36205 e68fb4a1fa1dcd6f018e7c034962fd88 185 Gene3D G3DSA:3.30.1360.40 31 105 1.2E-62 T 12-10-2018 AFR_36205 e68fb4a1fa1dcd6f018e7c034962fd88 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 25.906 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFR_36205 e68fb4a1fa1dcd6f018e7c034962fd88 185 Gene3D G3DSA:1.10.132.20 12 182 1.2E-62 T 12-10-2018 AFR_36205 e68fb4a1fa1dcd6f018e7c034962fd88 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 3.0E-61 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFR_20215 47dbe5b85778ae9482d2fdbd4881bc28 311 SUPERFAMILY SSF54001 88 169 2.7E-15 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_20215 47dbe5b85778ae9482d2fdbd4881bc28 311 SMART SM00460 85 149 3.2E-8 T 12-10-2018 IPR002931 Transglutaminase-like AFR_20215 47dbe5b85778ae9482d2fdbd4881bc28 311 Pfam PF01841 Transglutaminase-like superfamily 90 147 5.1E-9 T 12-10-2018 IPR002931 Transglutaminase-like AFR_20215 47dbe5b85778ae9482d2fdbd4881bc28 311 Gene3D G3DSA:3.10.620.30 87 172 1.1E-11 T 12-10-2018 AFR_33300 7194007fdca7581b084fa69842c47997 350 Pfam PF03459 TOBE domain 287 344 6.5E-10 T 12-10-2018 IPR005116 Transport-associated OB, type 1 AFR_33300 7194007fdca7581b084fa69842c47997 350 Gene3D G3DSA:2.40.50.140 246 344 9.7E-13 T 12-10-2018 AFR_33300 7194007fdca7581b084fa69842c47997 350 Pfam PF00005 ABC transporter 20 163 3.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_33300 7194007fdca7581b084fa69842c47997 350 SUPERFAMILY SSF50331 239 345 7.87E-16 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFR_33300 7194007fdca7581b084fa69842c47997 350 SMART SM00382 24 213 1.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33300 7194007fdca7581b084fa69842c47997 350 Gene3D G3DSA:2.40.50.100 273 343 9.7E-13 T 12-10-2018 AFR_33300 7194007fdca7581b084fa69842c47997 350 Gene3D G3DSA:3.40.50.300 16 239 6.8E-66 T 12-10-2018 AFR_33300 7194007fdca7581b084fa69842c47997 350 SUPERFAMILY SSF52540 7 238 1.03E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33300 7194007fdca7581b084fa69842c47997 350 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_32235 7c9b3ea4671f4f6fcf26ced0c3c758ac 105 SUPERFAMILY SSF54427 7 102 2.93E-13 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_32235 7c9b3ea4671f4f6fcf26ced0c3c758ac 105 Gene3D G3DSA:3.10.450.50 1 104 2.7E-30 T 12-10-2018 AFR_32235 7c9b3ea4671f4f6fcf26ced0c3c758ac 105 Pfam PF12680 SnoaL-like domain 7 100 9.3E-9 T 12-10-2018 IPR037401 SnoaL-like domain AFR_17125 274b37ceab0acc2159e5eff2efdbe0ba 277 SMART SM00530 9 81 3.1E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_17125 274b37ceab0acc2159e5eff2efdbe0ba 277 Pfam PF13560 Helix-turn-helix domain 5 84 1.2E-16 T 12-10-2018 AFR_17125 274b37ceab0acc2159e5eff2efdbe0ba 277 Gene3D G3DSA:1.10.260.40 22 99 3.1E-6 T 12-10-2018 AFR_17125 274b37ceab0acc2159e5eff2efdbe0ba 277 SUPERFAMILY SSF47413 28 80 6.29E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_29215 afc867ff035b7c28b76368b5a8a03a45 258 Gene3D G3DSA:3.40.50.1820 3 250 7.4E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_29215 afc867ff035b7c28b76368b5a8a03a45 258 Pfam PF12697 Alpha/beta hydrolase family 21 242 3.7E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_29215 afc867ff035b7c28b76368b5a8a03a45 258 SUPERFAMILY SSF53474 5 242 1.18E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22820 1246b60201ffd9fd969a738f5fe58eaa 176 SUPERFAMILY SSF88946 6 107 8.04E-25 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_22820 1246b60201ffd9fd969a738f5fe58eaa 176 Gene3D G3DSA:1.10.1740.10 9 92 1.1E-25 T 12-10-2018 AFR_22820 1246b60201ffd9fd969a738f5fe58eaa 176 Gene3D G3DSA:1.10.10.10 93 159 1.3E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22820 1246b60201ffd9fd969a738f5fe58eaa 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 154 1.8E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_22820 1246b60201ffd9fd969a738f5fe58eaa 176 Pfam PF04542 Sigma-70 region 2 28 98 6.1E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 Gene3D G3DSA:2.40.30.30 186 314 6.4E-42 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 SUPERFAMILY SSF82114 174 312 9.81E-41 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 309 8.2E-72 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 Gene3D G3DSA:3.40.50.620 1 185 5.0E-63 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 SUPERFAMILY SSF52374 16 175 1.13E-30 T 12-10-2018 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 Pfam PF01687 Riboflavin kinase 184 309 1.7E-33 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 SMART SM00904 183 310 8.5E-51 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 PIRSF PIRSF004491 1 313 1.8E-100 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFR_35920 5a4b08a5633300130b6af0febf1ce0f6 314 Pfam PF06574 FAD synthetase 16 166 1.3E-51 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFR_10185 5c9edecbd36b7fcac698ceb435bb2401 113 Gene3D G3DSA:3.10.180.10 1 113 3.1E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_10185 5c9edecbd36b7fcac698ceb435bb2401 113 SUPERFAMILY SSF54593 2 111 8.94E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_41255 cba719889c6ef67f8e70d20ad2a24b9e 342 SUPERFAMILY SSF53067 5 117 1.5E-16 T 12-10-2018 AFR_41255 cba719889c6ef67f8e70d20ad2a24b9e 342 Gene3D G3DSA:3.30.420.40 8 307 1.0E-50 T 12-10-2018 AFR_41255 cba719889c6ef67f8e70d20ad2a24b9e 342 Gene3D G3DSA:3.30.420.40 119 295 1.0E-50 T 12-10-2018 AFR_41255 cba719889c6ef67f8e70d20ad2a24b9e 342 SUPERFAMILY SSF53067 121 312 4.81E-27 T 12-10-2018 AFR_41255 cba719889c6ef67f8e70d20ad2a24b9e 342 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 11 307 5.7E-12 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 AFR_31240 62b8fe24c584ebb62102436469b24c75 272 Pfam PF06724 Domain of Unknown Function (DUF1206) 201 270 1.2E-21 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 AFR_31240 62b8fe24c584ebb62102436469b24c75 272 Pfam PF06724 Domain of Unknown Function (DUF1206) 27 91 3.0E-19 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 AFR_31240 62b8fe24c584ebb62102436469b24c75 272 Pfam PF06724 Domain of Unknown Function (DUF1206) 110 175 1.9E-12 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 Gene3D G3DSA:1.10.390.10 347 509 2.1E-40 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 67 111 1.1E-5 T 12-10-2018 IPR011096 FTP domain AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 SUPERFAMILY SSF49785 636 742 2.64E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 351 362 9.2E-7 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 416 432 9.2E-7 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 295 315 9.2E-7 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 202 338 1.8E-29 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 SUPERFAMILY SSF55486 202 509 4.21E-58 T 12-10-2018 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 Gene3D G3DSA:2.60.120.260 638 742 1.3E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 348 509 6.0E-35 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 Pfam PF01483 Proprotein convertase P-domain 664 742 5.9E-18 T 12-10-2018 IPR002884 P domain GO:0004252|GO:0006508 AFR_20605 d54b276db5e260bdafd3ea1762570b42 742 Gene3D G3DSA:3.10.170.10 200 341 1.8E-26 T 12-10-2018 AFR_19785 f67dcb7855b141c1a160333e1b31ac8e 303 SUPERFAMILY SSF46955 8 111 3.55E-25 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_19785 f67dcb7855b141c1a160333e1b31ac8e 303 Gene3D G3DSA:1.10.1660.10 2 123 1.1E-27 T 12-10-2018 AFR_19785 f67dcb7855b141c1a160333e1b31ac8e 303 SMART SM00422 8 77 2.4E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_19785 f67dcb7855b141c1a160333e1b31ac8e 303 Pfam PF13411 MerR HTH family regulatory protein 9 75 4.3E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_19785 f67dcb7855b141c1a160333e1b31ac8e 303 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 5.0E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_19785 f67dcb7855b141c1a160333e1b31ac8e 303 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 5.0E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_19785 f67dcb7855b141c1a160333e1b31ac8e 303 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 5.0E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_37885 c8bde504db06ed8fd3ef58e46287de99 97 SUPERFAMILY SSF55248 1 93 6.54E-25 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_37885 c8bde504db06ed8fd3ef58e46287de99 97 Gene3D G3DSA:3.30.1360.20 4 97 7.5E-25 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_37885 c8bde504db06ed8fd3ef58e46287de99 97 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 92 2.3E-25 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_37955 7384dc9be5965abae25d253b84db9b8a 248 SUPERFAMILY SSF55729 12 219 1.2E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_37955 7384dc9be5965abae25d253b84db9b8a 248 Gene3D G3DSA:3.40.630.30 16 172 9.3E-26 T 12-10-2018 AFR_37955 7384dc9be5965abae25d253b84db9b8a 248 Pfam PF13444 Acetyltransferase (GNAT) domain 29 131 2.7E-32 T 12-10-2018 AFR_09600 c8652e08e78ced78a46e21854a763981 164 Gene3D G3DSA:3.30.420.10 3 164 1.1E-60 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_09600 c8652e08e78ced78a46e21854a763981 164 Hamap MF_00977 3'-5' exoribonuclease. 3 164 43.14 T 12-10-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 AFR_09600 c8652e08e78ced78a46e21854a763981 164 Pfam PF16473 3' exoribonuclease, RNase T-like 4 159 4.8E-18 T 12-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain AFR_11495 2d07980d663a4f98cf05a7806a02d5cf 561 SMART SM00642 29 431 1.3E-121 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_11495 2d07980d663a4f98cf05a7806a02d5cf 561 Pfam PF11941 Domain of unknown function (DUF3459) 478 559 2.3E-9 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) AFR_11495 2d07980d663a4f98cf05a7806a02d5cf 561 Pfam PF00128 Alpha amylase, catalytic domain 44 403 4.3E-75 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_11495 2d07980d663a4f98cf05a7806a02d5cf 561 Gene3D G3DSA:3.20.20.80 21 487 5.7E-145 T 12-10-2018 AFR_11495 2d07980d663a4f98cf05a7806a02d5cf 561 SUPERFAMILY SSF51445 20 492 6.61E-125 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_11495 2d07980d663a4f98cf05a7806a02d5cf 561 Gene3D G3DSA:3.90.400.10 121 198 5.7E-145 T 12-10-2018 AFR_24700 c22950653926300df564a82c4f0d7abf 421 Gene3D G3DSA:1.20.1440.30 137 261 9.2E-64 T 12-10-2018 AFR_24700 c22950653926300df564a82c4f0d7abf 421 Pfam PF05139 Erythromycin esterase 58 398 1.0E-110 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 AFR_24700 c22950653926300df564a82c4f0d7abf 421 Gene3D G3DSA:3.30.1870.10 60 136 9.2E-64 T 12-10-2018 AFR_24700 c22950653926300df564a82c4f0d7abf 421 Gene3D G3DSA:3.40.1660.10 14 399 9.2E-64 T 12-10-2018 AFR_24700 c22950653926300df564a82c4f0d7abf 421 SUPERFAMILY SSF159501 11 404 8.02E-121 T 12-10-2018 AFR_24700 c22950653926300df564a82c4f0d7abf 421 PIRSF PIRSF036794 3 409 7.1E-94 T 12-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type AFR_09880 67702463876fcfeb4879d7662dba0782 657 Pfam PF00817 impB/mucB/samB family 30 151 7.1E-14 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFR_09880 67702463876fcfeb4879d7662dba0782 657 Gene3D G3DSA:2.30.40.20 34 71 3.1E-16 T 12-10-2018 AFR_09880 67702463876fcfeb4879d7662dba0782 657 SUPERFAMILY SSF56672 7 224 5.07E-33 T 12-10-2018 AFR_09880 67702463876fcfeb4879d7662dba0782 657 Gene3D G3DSA:1.10.150.20 168 218 3.1E-16 T 12-10-2018 AFR_09880 67702463876fcfeb4879d7662dba0782 657 Gene3D G3DSA:3.30.70.270 72 223 3.1E-16 T 12-10-2018 AFR_19275 0d8603135ad92e2d4214d5379f53328f 167 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 3 167 1.6E-58 T 12-10-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 AFR_19275 0d8603135ad92e2d4214d5379f53328f 167 Gene3D G3DSA:2.60.130.10 1 167 4.2E-57 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_19275 0d8603135ad92e2d4214d5379f53328f 167 Pfam PF00775 Dioxygenase 33 156 6.4E-10 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 AFR_19275 0d8603135ad92e2d4214d5379f53328f 167 SUPERFAMILY SSF49482 2 166 1.31E-45 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_20455 e85176b10e56c0ec266e8bd9c13748f5 360 Pfam PF06224 Winged helix DNA-binding domain 30 350 3.5E-59 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 AFR_27385 079f755e407fcadec452eba32c059a4c 712 Pfam PF13515 Fusaric acid resistance protein-like 394 516 1.7E-12 T 12-10-2018 AFR_36535 b5607a7d03493a18095b40860798b9b6 57 Pfam PF01783 Ribosomal L32p protein family 2 56 6.1E-26 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36535 b5607a7d03493a18095b40860798b9b6 57 SUPERFAMILY SSF57829 2 57 1.1E-20 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFR_36535 b5607a7d03493a18095b40860798b9b6 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 19.363 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36535 b5607a7d03493a18095b40860798b9b6 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 8.1E-26 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_13820 0b68f5a86d28862d653c7fee5182bc6c 287 Pfam PF02669 K+-transporting ATPase, c chain 12 103 5.5E-22 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFR_13820 0b68f5a86d28862d653c7fee5182bc6c 287 Pfam PF02669 K+-transporting ATPase, c chain 212 285 3.2E-32 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFR_13820 0b68f5a86d28862d653c7fee5182bc6c 287 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 7 287 28.513 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFR_20650 222c7a483fc1b2fae73f2dbb358f6baf 497 Pfam PF13520 Amino acid permease 23 456 1.6E-23 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_20650 222c7a483fc1b2fae73f2dbb358f6baf 497 Gene3D G3DSA:1.20.1740.10 18 463 1.7E-34 T 12-10-2018 AFR_20650 222c7a483fc1b2fae73f2dbb358f6baf 497 PIRSF PIRSF006060 7 474 3.0E-42 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_09670 67342d3c2f3e2f6e62fc01ff01840483 127 SUPERFAMILY SSF159238 1 126 2.62E-37 T 12-10-2018 IPR023159 SO1590-like superfamily AFR_09670 67342d3c2f3e2f6e62fc01ff01840483 127 Pfam PF11528 Protein of unknown function (DUF3224) 7 124 6.1E-34 T 12-10-2018 IPR021607 Protein of unknown function DUF3224 AFR_09670 67342d3c2f3e2f6e62fc01ff01840483 127 Gene3D G3DSA:2.40.350.10 1 127 3.8E-43 T 12-10-2018 IPR023159 SO1590-like superfamily AFR_30695 58e9eeba092be5182d28bd8ddc2e9e77 271 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 1.5E-18 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFR_30695 58e9eeba092be5182d28bd8ddc2e9e77 271 SUPERFAMILY SSF51735 101 265 2.49E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_30695 58e9eeba092be5182d28bd8ddc2e9e77 271 Gene3D G3DSA:3.40.50.720 101 242 6.4E-72 T 12-10-2018 AFR_30695 58e9eeba092be5182d28bd8ddc2e9e77 271 SUPERFAMILY SSF53223 3 100 2.53E-23 T 12-10-2018 AFR_30695 58e9eeba092be5182d28bd8ddc2e9e77 271 Gene3D G3DSA:3.40.50.10860 6 256 6.4E-72 T 12-10-2018 AFR_38305 4eb95487344d819b04d3ce7baaffbbca 985 Pfam PF03699 Uncharacterised protein family (UPF0182) 5 803 1.3E-263 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 AFR_38305 4eb95487344d819b04d3ce7baaffbbca 985 Hamap MF_01600 UPF0182 protein . 1 883 17.458 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 AFR_21150 4210d2bc89bd7193e03e1eef19fe4e49 639 PIRSF PIRSF001589 1 638 6.0E-166 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFR_21150 4210d2bc89bd7193e03e1eef19fe4e49 639 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 557 4.6E-136 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFR_21150 4210d2bc89bd7193e03e1eef19fe4e49 639 Gene3D G3DSA:3.60.20.10 17 196 5.1E-51 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_21150 4210d2bc89bd7193e03e1eef19fe4e49 639 SUPERFAMILY SSF52402 241 615 3.67E-78 T 12-10-2018 AFR_21150 4210d2bc89bd7193e03e1eef19fe4e49 639 Pfam PF13537 Glutamine amidotransferase domain 53 176 8.7E-36 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFR_21150 4210d2bc89bd7193e03e1eef19fe4e49 639 SUPERFAMILY SSF56235 1 234 1.72E-57 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_21150 4210d2bc89bd7193e03e1eef19fe4e49 639 Pfam PF00733 Asparagine synthase 251 619 9.0E-98 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFR_36130 aa38f89941d560fd77eaec6d79fda317 279 Pfam PF13312 Domain of unknown function (DUF4081) 47 151 4.4E-38 T 12-10-2018 IPR025289 Domain of unknown function DUF4081 AFR_36130 aa38f89941d560fd77eaec6d79fda317 279 Gene3D G3DSA:3.40.630.30 66 278 8.0E-22 T 12-10-2018 AFR_36130 aa38f89941d560fd77eaec6d79fda317 279 Pfam PF00583 Acetyltransferase (GNAT) family 209 268 3.3E-11 T 12-10-2018 IPR000182 GNAT domain AFR_36130 aa38f89941d560fd77eaec6d79fda317 279 PIRSF PIRSF021603 2 279 6.2E-101 T 12-10-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like AFR_36130 aa38f89941d560fd77eaec6d79fda317 279 SUPERFAMILY SSF55729 38 273 1.63E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_09420 62567a76cb33d3904ee25528731236fc 198 Gene3D G3DSA:1.20.120.80 16 198 5.7E-55 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09420 62567a76cb33d3904ee25528731236fc 198 SUPERFAMILY SSF81452 10 197 4.97E-55 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09420 62567a76cb33d3904ee25528731236fc 198 Pfam PF00510 Cytochrome c oxidase subunit III 18 196 2.0E-21 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_38490 c6d4185502dee756a9e0b4badc200ee9 251 Pfam PF05988 Bacterial protein of unknown function (DUF899) 6 232 2.5E-79 T 12-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like AFR_23830 baa25f899996328e2b3e665a03256f2f 1151 Gene3D G3DSA:2.60.120.200 793 1009 6.1E-24 T 12-10-2018 AFR_23830 baa25f899996328e2b3e665a03256f2f 1151 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 269 334 1.5E-11 T 12-10-2018 AFR_23830 baa25f899996328e2b3e665a03256f2f 1151 SUPERFAMILY SSF49899 789 1009 1.21E-25 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_23830 baa25f899996328e2b3e665a03256f2f 1151 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 838 1003 1.9E-16 T 12-10-2018 AFR_17925 668e8361a767301af176a3474bd8135d 217 SUPERFAMILY SSF52218 5 162 1.46E-30 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_17925 668e8361a767301af176a3474bd8135d 217 Pfam PF02525 Flavodoxin-like fold 8 161 6.8E-25 T 12-10-2018 IPR003680 Flavodoxin-like fold AFR_17925 668e8361a767301af176a3474bd8135d 217 Gene3D G3DSA:3.40.50.360 5 207 2.8E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_17925 668e8361a767301af176a3474bd8135d 217 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 6 207 23.042 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 AFR_34800 3bcb44862a1f8f772e6054bd8878a1fd 161 Gene3D G3DSA:3.10.20.30 1 74 1.1E-30 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_34800 3bcb44862a1f8f772e6054bd8878a1fd 161 SUPERFAMILY SSF47741 82 160 2.36E-27 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily AFR_34800 3bcb44862a1f8f772e6054bd8878a1fd 161 Pfam PF01799 [2Fe-2S] binding domain 71 155 1.6E-29 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFR_34800 3bcb44862a1f8f772e6054bd8878a1fd 161 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 56 1.6E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_34800 3bcb44862a1f8f772e6054bd8878a1fd 161 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFR_34800 3bcb44862a1f8f772e6054bd8878a1fd 161 SUPERFAMILY SSF54292 2 86 3.15E-26 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_34800 3bcb44862a1f8f772e6054bd8878a1fd 161 Gene3D G3DSA:1.10.150.120 75 161 9.4E-32 T 12-10-2018 AFR_33090 324bb1e4d500f7a146a0eaa175c6244f 133 SUPERFAMILY SSF54427 30 129 5.61E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_33090 324bb1e4d500f7a146a0eaa175c6244f 133 Gene3D G3DSA:3.10.450.50 9 130 1.5E-34 T 12-10-2018 AFR_33090 324bb1e4d500f7a146a0eaa175c6244f 133 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 7 129 27.031 T 12-10-2018 IPR023006 Uncharacterised protein family UPF0225 AFR_33090 324bb1e4d500f7a146a0eaa175c6244f 133 Pfam PF02810 SEC-C motif 10 25 1.5E-5 T 12-10-2018 IPR004027 SEC-C motif AFR_14685 440dee06596451540bc4424ce8ad890a 381 PRINTS PR00412 Epoxide hydrolase signature 185 198 7.5E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_14685 440dee06596451540bc4424ce8ad890a 381 PRINTS PR00412 Epoxide hydrolase signature 171 184 7.5E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_14685 440dee06596451540bc4424ce8ad890a 381 PRINTS PR00412 Epoxide hydrolase signature 320 336 7.5E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_14685 440dee06596451540bc4424ce8ad890a 381 PRINTS PR00412 Epoxide hydrolase signature 126 141 7.5E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_14685 440dee06596451540bc4424ce8ad890a 381 PRINTS PR00412 Epoxide hydrolase signature 352 374 7.5E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_14685 440dee06596451540bc4424ce8ad890a 381 PRINTS PR00412 Epoxide hydrolase signature 97 115 7.5E-17 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_14685 440dee06596451540bc4424ce8ad890a 381 SUPERFAMILY SSF53474 4 377 2.65E-95 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14685 440dee06596451540bc4424ce8ad890a 381 PIRSF PIRSF001112 1 381 1.5E-128 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_14685 440dee06596451540bc4424ce8ad890a 381 Gene3D G3DSA:3.40.50.1820 3 381 2.5E-138 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14685 440dee06596451540bc4424ce8ad890a 381 Pfam PF06441 Epoxide hydrolase N terminus 5 106 6.4E-32 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_02330 eeb7c5a4115715bd5f9532bae4f4419f 283 Gene3D G3DSA:3.40.830.10 1 257 1.3E-84 T 12-10-2018 AFR_02330 eeb7c5a4115715bd5f9532bae4f4419f 283 PIRSF PIRSF006157 1 258 3.6E-78 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 AFR_02330 eeb7c5a4115715bd5f9532bae4f4419f 283 SUPERFAMILY SSF53213 4 256 2.09E-83 T 12-10-2018 AFR_02330 eeb7c5a4115715bd5f9532bae4f4419f 283 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 24 256 2.4E-29 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFR_28385 700b259f644a79a10aa65532255af3a0 532 Pfam PF01039 Carboxyl transferase domain 48 521 2.9E-134 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFR_28385 700b259f644a79a10aa65532255af3a0 532 Gene3D G3DSA:3.90.226.10 268 532 5.3E-85 T 12-10-2018 AFR_28385 700b259f644a79a10aa65532255af3a0 532 SUPERFAMILY SSF52096 22 272 8.75E-64 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_28385 700b259f644a79a10aa65532255af3a0 532 Gene3D G3DSA:3.90.226.10 1 267 6.3E-81 T 12-10-2018 AFR_28385 700b259f644a79a10aa65532255af3a0 532 SUPERFAMILY SSF52096 269 522 8.35E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_11390 985c81e4ed0dab55b7182414528e9964 192 SUPERFAMILY SSF52833 1 156 2.05E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_11390 985c81e4ed0dab55b7182414528e9964 192 Gene3D G3DSA:3.40.30.10 2 192 4.9E-50 T 12-10-2018 AFR_11390 985c81e4ed0dab55b7182414528e9964 192 Pfam PF01323 DSBA-like thioredoxin domain 5 132 5.6E-6 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 AFR_06685 c52a121d8b0d18e1d8f8fe12b8b3195f 571 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 508 548 1.6E-10 T 12-10-2018 IPR011964 YVTN beta-propeller repeat AFR_06685 c52a121d8b0d18e1d8f8fe12b8b3195f 571 Pfam PF10282 Lactonase, 7-bladed beta-propeller 326 569 1.6E-9 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller AFR_06685 c52a121d8b0d18e1d8f8fe12b8b3195f 571 SUPERFAMILY SSF51004 379 567 3.4E-39 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily AFR_06685 c52a121d8b0d18e1d8f8fe12b8b3195f 571 Gene3D G3DSA:2.130.10.10 390 570 4.5E-47 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_06685 c52a121d8b0d18e1d8f8fe12b8b3195f 571 Gene3D G3DSA:2.130.10.10 265 389 1.1E-23 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_06685 c52a121d8b0d18e1d8f8fe12b8b3195f 571 SUPERFAMILY SSF50974 269 423 1.28E-21 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 AFR_06775 82211afdf73ddc96fca42d5efe876509 114 Pfam PF05239 PRC-barrel domain 22 57 5.6E-5 T 12-10-2018 IPR027275 PRC-barrel domain AFR_06775 82211afdf73ddc96fca42d5efe876509 114 SUPERFAMILY SSF50346 22 86 1.37E-7 T 12-10-2018 IPR011033 PRC-barrel-like superfamily AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 Gene3D G3DSA:2.40.50.140 128 185 1.3E-25 T 12-10-2018 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 PIRSF PIRSF005901 1 185 8.7E-67 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 SMART SM00841 129 184 6.3E-31 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 Gene3D G3DSA:2.40.50.140 64 127 8.7E-22 T 12-10-2018 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 Pfam PF09285 Elongation factor P, C-terminal 130 184 3.2E-26 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 Gene3D G3DSA:2.30.30.30 1 62 3.8E-28 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 SUPERFAMILY SSF50249 129 184 3.77E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 8.0E-75 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 SUPERFAMILY SSF50104 1 63 4.87E-20 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 SMART SM01185 67 121 2.3E-23 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 48.82 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 SUPERFAMILY SSF50249 65 129 9.42E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 59 7.0E-26 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like AFR_30650 2d913925a89d1e9a3d2fb02283551b51 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.4E-19 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFR_27525 4888d316b14d3ec5f089a7dc2a2d8f7b 108 Pfam PF11829 Protein of unknown function (DUF3349) 8 101 1.5E-33 T 12-10-2018 IPR021784 Protein of unknown function DUF3349 AFR_27525 4888d316b14d3ec5f089a7dc2a2d8f7b 108 Gene3D G3DSA:1.10.150.430 2 108 1.6E-33 T 12-10-2018 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 SUPERFAMILY SSF46894 814 882 7.48E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 SUPERFAMILY SSF52540 4 183 1.28E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 Gene3D G3DSA:3.40.50.300 4 155 2.1E-5 T 12-10-2018 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 Gene3D G3DSA:1.10.10.10 800 882 5.3E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 SMART SM00421 822 879 1.8E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 ProSitePatterns PS00622 LuxR-type HTH domain signature. 839 866 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 839 855 1.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 825 839 1.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 855 867 1.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 Gene3D G3DSA:1.25.40.10 525 788 8.0E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 Pfam PF00196 Bacterial regulatory proteins, luxR family 824 878 1.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_14550 8e4846e04c4597fecbe6fc12c2ea201a 884 Pfam PF13191 AAA ATPase domain 5 78 3.0E-11 T 12-10-2018 AFR_19180 44226af83f9d2da797acca4152cb9376 314 Gene3D G3DSA:3.20.20.140 1 314 1.0E-91 T 12-10-2018 AFR_19180 44226af83f9d2da797acca4152cb9376 314 SUPERFAMILY SSF51556 3 313 2.01E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_19180 44226af83f9d2da797acca4152cb9376 314 Pfam PF00962 Adenosine/AMP deaminase 5 313 9.6E-59 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 AFR_19180 44226af83f9d2da797acca4152cb9376 314 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 5 313 3.3E-79 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 AFR_00345 50e056f02adaba4fe1064e4cfc586757 294 SUPERFAMILY SSF49899 179 291 2.8E-11 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_00345 50e056f02adaba4fe1064e4cfc586757 294 Gene3D G3DSA:2.60.120.200 160 294 2.3E-11 T 12-10-2018 AFR_00345 50e056f02adaba4fe1064e4cfc586757 294 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 182 290 7.6E-11 T 12-10-2018 AFR_40655 fb4814651f6fe368b8937f43ced59bcb 296 Pfam PF00561 alpha/beta hydrolase fold 60 151 7.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_40655 fb4814651f6fe368b8937f43ced59bcb 296 Gene3D G3DSA:3.40.50.1820 35 295 1.6E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_40655 fb4814651f6fe368b8937f43ced59bcb 296 SUPERFAMILY SSF53474 31 275 3.03E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19765 544861f14b721ddb9fb5454398c8708b 251 SUPERFAMILY SSF53474 39 245 1.3E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19765 544861f14b721ddb9fb5454398c8708b 251 Pfam PF00756 Putative esterase 47 184 1.8E-12 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFR_19765 544861f14b721ddb9fb5454398c8708b 251 Gene3D G3DSA:3.40.50.1820 27 249 8.8E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_09305 8b05f6e2e455701aa9c0067c716a3e8c 939 SMART SM00028 632 665 3.5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_09305 8b05f6e2e455701aa9c0067c716a3e8c 939 SMART SM00028 555 588 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_09305 8b05f6e2e455701aa9c0067c716a3e8c 939 Pfam PF14903 WG containing repeat 794 823 0.012 T 12-10-2018 IPR032774 WG containing repeat AFR_09305 8b05f6e2e455701aa9c0067c716a3e8c 939 Pfam PF14903 WG containing repeat 718 746 0.025 T 12-10-2018 IPR032774 WG containing repeat AFR_09305 8b05f6e2e455701aa9c0067c716a3e8c 939 SUPERFAMILY SSF48452 554 669 4.61E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_09305 8b05f6e2e455701aa9c0067c716a3e8c 939 Gene3D G3DSA:1.25.40.10 530 688 1.6E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_40690 da4b54e5a6dfdfb7bf82270769ebd744 141 Gene3D G3DSA:1.10.10.10 1 84 8.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40690 da4b54e5a6dfdfb7bf82270769ebd744 141 Pfam PF01475 Ferric uptake regulator family 12 123 4.0E-24 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFR_40690 da4b54e5a6dfdfb7bf82270769ebd744 141 Gene3D G3DSA:3.30.1490.190 86 140 1.6E-13 T 12-10-2018 AFR_40690 da4b54e5a6dfdfb7bf82270769ebd744 141 SUPERFAMILY SSF46785 6 135 6.3E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 SUPERFAMILY SSF51905 11 366 4.03E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 Gene3D G3DSA:3.40.30.120 413 536 1.4E-25 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 Gene3D G3DSA:3.30.9.50 77 295 4.5E-111 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 5.3E-39 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 175 190 5.3E-39 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 5.3E-39 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 349 365 5.3E-39 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 5.3E-39 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 349 5.3E-39 T 12-10-2018 AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 Gene3D G3DSA:3.50.50.60 13 358 4.5E-111 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13090 2a4cded135cc42c03981a994ee2ae835 542 Pfam PF01494 FAD binding domain 11 360 2.3E-75 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_15910 07430e3a22a53f883f74593044e5dfe7 218 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 165 193 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFR_15910 07430e3a22a53f883f74593044e5dfe7 218 Gene3D G3DSA:2.160.10.10 87 212 4.7E-27 T 12-10-2018 AFR_15910 07430e3a22a53f883f74593044e5dfe7 218 Gene3D G3DSA:3.40.50.20 1 84 4.6E-15 T 12-10-2018 AFR_15910 07430e3a22a53f883f74593044e5dfe7 218 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 3 205 2.2E-58 T 12-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like AFR_15910 07430e3a22a53f883f74593044e5dfe7 218 SUPERFAMILY SSF51161 2 206 1.66E-36 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_23525 c559f0e33a3cb8cf160eb79337c44258 153 SUPERFAMILY SSF55961 2 146 1.16E-27 T 12-10-2018 AFR_23525 c559f0e33a3cb8cf160eb79337c44258 153 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 142 1.8E-15 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_23525 c559f0e33a3cb8cf160eb79337c44258 153 Gene3D G3DSA:3.30.530.20 2 152 3.7E-31 T 12-10-2018 IPR023393 START-like domain superfamily AFR_10615 0062b2fa029b9e4f36c2aca42d24a0ff 249 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 10 246 2.2E-65 T 12-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 AFR_10615 0062b2fa029b9e4f36c2aca42d24a0ff 249 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 236 1.1E-71 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 AFR_10615 0062b2fa029b9e4f36c2aca42d24a0ff 249 Gene3D G3DSA:3.40.50.1360 1 247 5.4E-82 T 12-10-2018 AFR_10615 0062b2fa029b9e4f36c2aca42d24a0ff 249 SUPERFAMILY SSF100950 6 247 1.2E-60 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_29300 332aa71f5cc353d3de60ed2cf7f2a8a7 228 Pfam PF13460 NAD(P)H-binding 7 190 5.8E-31 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_29300 332aa71f5cc353d3de60ed2cf7f2a8a7 228 Gene3D G3DSA:3.40.50.720 2 221 2.2E-42 T 12-10-2018 AFR_29300 332aa71f5cc353d3de60ed2cf7f2a8a7 228 SUPERFAMILY SSF51735 2 205 3.13E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19595 5c91870ee361a6ceb691cc7b17790837 451 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_19595 5c91870ee361a6ceb691cc7b17790837 451 PIRSF PIRSF000139 24 444 1.1E-128 T 12-10-2018 AFR_19595 5c91870ee361a6ceb691cc7b17790837 451 Gene3D G3DSA:1.10.1060.10 24 122 6.9E-9 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFR_19595 5c91870ee361a6ceb691cc7b17790837 451 SUPERFAMILY SSF54862 34 141 1.13E-20 T 12-10-2018 AFR_19595 5c91870ee361a6ceb691cc7b17790837 451 Pfam PF13183 4Fe-4S dicluster domain 35 101 3.6E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_19595 5c91870ee361a6ceb691cc7b17790837 451 Pfam PF02754 Cysteine-rich domain 204 285 2.4E-14 T 12-10-2018 IPR004017 Cysteine-rich domain AFR_19595 5c91870ee361a6ceb691cc7b17790837 451 Pfam PF02754 Cysteine-rich domain 332 416 1.2E-12 T 12-10-2018 IPR004017 Cysteine-rich domain AFR_25670 15145cabe3408800a7d613f02230b50e 465 SMART SM00138 4 269 4.2E-50 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_25670 15145cabe3408800a7d613f02230b50e 465 Pfam PF01739 CheR methyltransferase, SAM binding domain 71 257 3.5E-47 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AFR_25670 15145cabe3408800a7d613f02230b50e 465 Gene3D G3DSA:3.40.50.150 70 270 1.3E-53 T 12-10-2018 AFR_25670 15145cabe3408800a7d613f02230b50e 465 SUPERFAMILY SSF48452 303 430 9.38E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25670 15145cabe3408800a7d613f02230b50e 465 SUPERFAMILY SSF53335 71 265 8.53E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_25670 15145cabe3408800a7d613f02230b50e 465 Gene3D G3DSA:1.25.40.10 295 447 2.6E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25670 15145cabe3408800a7d613f02230b50e 465 PRINTS PR00996 Glutamate methyltransferase family signature 227 250 1.0E-25 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_25670 15145cabe3408800a7d613f02230b50e 465 PRINTS PR00996 Glutamate methyltransferase family signature 104 124 1.0E-25 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_25670 15145cabe3408800a7d613f02230b50e 465 PRINTS PR00996 Glutamate methyltransferase family signature 64 76 1.0E-25 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_25670 15145cabe3408800a7d613f02230b50e 465 PRINTS PR00996 Glutamate methyltransferase family signature 138 154 1.0E-25 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_25670 15145cabe3408800a7d613f02230b50e 465 PRINTS PR00996 Glutamate methyltransferase family signature 208 222 1.0E-25 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_11215 b4a13aac92260b1dc11d6b4fe3765fe7 149 Gene3D G3DSA:3.30.530.20 2 149 2.2E-17 T 12-10-2018 IPR023393 START-like domain superfamily AFR_11215 b4a13aac92260b1dc11d6b4fe3765fe7 149 SUPERFAMILY SSF55961 1 148 2.96E-26 T 12-10-2018 AFR_11215 b4a13aac92260b1dc11d6b4fe3765fe7 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 143 1.1E-6 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_38025 71fc2f10b16f5946a2eaeca448cc69e8 98 SUPERFAMILY SSF51306 5 94 5.49E-18 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFR_38025 71fc2f10b16f5946a2eaeca448cc69e8 98 Pfam PF00717 Peptidase S24-like 8 67 3.0E-11 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFR_38025 71fc2f10b16f5946a2eaeca448cc69e8 98 Gene3D G3DSA:2.10.109.10 3 96 8.0E-11 T 12-10-2018 AFR_38675 4e4e03c15f52183f292405ef7fdd2c37 497 Gene3D G3DSA:3.40.50.2000 18 194 2.1E-11 T 12-10-2018 AFR_38675 4e4e03c15f52183f292405ef7fdd2c37 497 Pfam PF00534 Glycosyl transferases group 1 197 337 3.2E-27 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_38675 4e4e03c15f52183f292405ef7fdd2c37 497 SUPERFAMILY SSF53756 23 372 1.35E-58 T 12-10-2018 AFR_38675 4e4e03c15f52183f292405ef7fdd2c37 497 Pfam PF13439 Glycosyltransferase Family 4 27 185 8.6E-11 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_38675 4e4e03c15f52183f292405ef7fdd2c37 497 Gene3D G3DSA:3.40.50.2000 195 366 3.1E-34 T 12-10-2018 AFR_28680 244beb2a1587606b6fe773fa8736712d 642 Pfam PF00656 Caspase domain 47 151 3.4E-7 T 12-10-2018 AFR_28680 244beb2a1587606b6fe773fa8736712d 642 Gene3D G3DSA:3.40.50.1460 8 234 2.1E-10 T 12-10-2018 AFR_28680 244beb2a1587606b6fe773fa8736712d 642 SUPERFAMILY SSF52129 34 199 3.45E-7 T 12-10-2018 IPR029030 Caspase-like domain superfamily AFR_07045 8f9844b1bb8e45fc7b6f8bf0ac2ca7dc 307 Pfam PF03707 Bacterial signalling protein N terminal repeat 57 112 1.4E-15 T 12-10-2018 IPR005330 MHYT domain AFR_07045 8f9844b1bb8e45fc7b6f8bf0ac2ca7dc 307 Pfam PF03707 Bacterial signalling protein N terminal repeat 184 237 1.9E-7 T 12-10-2018 IPR005330 MHYT domain AFR_07045 8f9844b1bb8e45fc7b6f8bf0ac2ca7dc 307 Pfam PF03707 Bacterial signalling protein N terminal repeat 121 175 2.5E-15 T 12-10-2018 IPR005330 MHYT domain AFR_04925 d544f902aafef6c3572bd99767ae36a7 206 SUPERFAMILY SSF52540 1 145 1.01E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35805 6779fd3a671037bb33d94451e2b14faf 195 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 66 88 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_35805 6779fd3a671037bb33d94451e2b14faf 195 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 20 188 4.0E-40 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFR_35805 6779fd3a671037bb33d94451e2b14faf 195 Gene3D G3DSA:1.20.120.1760 13 125 3.1E-6 T 12-10-2018 AFR_35805 6779fd3a671037bb33d94451e2b14faf 195 Pfam PF01066 CDP-alcohol phosphatidyltransferase 20 88 5.3E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_35805 6779fd3a671037bb33d94451e2b14faf 195 PIRSF PIRSF000847 14 195 8.2E-44 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFR_27330 8f72e449bef9d283ac387935df2c9367 822 SUPERFAMILY SSF51445 311 597 2.16E-58 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27330 8f72e449bef9d283ac387935df2c9367 822 Gene3D G3DSA:2.60.120.200 626 820 7.3E-37 T 12-10-2018 AFR_27330 8f72e449bef9d283ac387935df2c9367 822 SUPERFAMILY SSF49899 624 821 1.8E-38 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_27330 8f72e449bef9d283ac387935df2c9367 822 Pfam PF00703 Glycosyl hydrolases family 2 259 314 4.9E-11 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_27330 8f72e449bef9d283ac387935df2c9367 822 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 662 815 1.6E-29 T 12-10-2018 AFR_27330 8f72e449bef9d283ac387935df2c9367 822 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 91 214 9.8E-13 T 12-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_27330 8f72e449bef9d283ac387935df2c9367 822 Gene3D G3DSA:3.20.20.80 325 603 1.3E-46 T 12-10-2018 AFR_27330 8f72e449bef9d283ac387935df2c9367 822 SUPERFAMILY SSF49785 47 218 4.98E-44 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_27330 8f72e449bef9d283ac387935df2c9367 822 Gene3D G3DSA:2.60.120.260 51 218 7.9E-38 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_27330 8f72e449bef9d283ac387935df2c9367 822 SUPERFAMILY SSF49303 223 315 5.18E-15 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily AFR_27330 8f72e449bef9d283ac387935df2c9367 822 Gene3D G3DSA:2.60.40.10 221 314 1.1E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_27330 8f72e449bef9d283ac387935df2c9367 822 SMART SM00560 679 812 7.5E-21 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 SMART SM00228 219 301 2.7E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 PRINTS PR00834 HtrA/DegQ protease family signature 54 66 4.8E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 PRINTS PR00834 HtrA/DegQ protease family signature 177 194 4.8E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 PRINTS PR00834 HtrA/DegQ protease family signature 155 172 4.8E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 PRINTS PR00834 HtrA/DegQ protease family signature 115 139 4.8E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 PRINTS PR00834 HtrA/DegQ protease family signature 259 271 4.8E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 PRINTS PR00834 HtrA/DegQ protease family signature 75 95 4.8E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 Pfam PF13180 PDZ domain 241 301 3.3E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 SUPERFAMILY SSF50156 204 306 7.49E-15 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 Pfam PF13365 Trypsin-like peptidase domain 45 184 2.8E-29 T 12-10-2018 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 SUPERFAMILY SSF50494 20 226 1.35E-46 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 Gene3D G3DSA:2.30.42.10 216 314 3.0E-16 T 12-10-2018 AFR_05475 d510b5aa78e13718338eb9cb1c8d4f80 314 Gene3D G3DSA:2.40.10.120 10 215 2.6E-53 T 12-10-2018 AFR_42870 b4ae1cb454f4de53c8c4a1128c39494a 201 SUPERFAMILY SSF46785 5 179 3.22E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_42870 b4ae1cb454f4de53c8c4a1128c39494a 201 Gene3D G3DSA:1.10.10.10 1 101 4.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42870 b4ae1cb454f4de53c8c4a1128c39494a 201 Pfam PF03551 Transcriptional regulator PadR-like family 9 91 3.5E-15 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_00455 47114027429a4c5181bf3a994ea06417 264 Gene3D G3DSA:3.40.50.1820 3 258 1.1E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_00455 47114027429a4c5181bf3a994ea06417 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 6.9E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00455 47114027429a4c5181bf3a994ea06417 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 93 6.9E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00455 47114027429a4c5181bf3a994ea06417 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 6.9E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00455 47114027429a4c5181bf3a994ea06417 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 6.9E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00455 47114027429a4c5181bf3a994ea06417 264 SUPERFAMILY SSF53474 4 257 4.48E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_00455 47114027429a4c5181bf3a994ea06417 264 Pfam PF00561 alpha/beta hydrolase fold 16 250 6.4E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_02900 bb107995bd355c257c8077471e5438e5 589 Pfam PF07690 Major Facilitator Superfamily 18 431 2.8E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_02900 bb107995bd355c257c8077471e5438e5 589 SUPERFAMILY SSF103473 8 554 1.22E-50 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_02900 bb107995bd355c257c8077471e5438e5 589 Gene3D G3DSA:1.20.1720.10 17 234 6.2E-30 T 12-10-2018 AFR_02900 bb107995bd355c257c8077471e5438e5 589 Gene3D G3DSA:1.20.1250.20 287 440 3.4E-17 T 12-10-2018 AFR_19845 7fea9a608d80eb916dd6beecbd1fb949 448 Gene3D G3DSA:1.20.1250.20 245 446 9.0E-20 T 12-10-2018 AFR_19845 7fea9a608d80eb916dd6beecbd1fb949 448 SUPERFAMILY SSF103473 2 439 3.01E-56 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_19845 7fea9a608d80eb916dd6beecbd1fb949 448 Gene3D G3DSA:1.20.1720.10 1 206 9.8E-41 T 12-10-2018 AFR_19845 7fea9a608d80eb916dd6beecbd1fb949 448 Pfam PF07690 Major Facilitator Superfamily 3 394 6.3E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_19845 7fea9a608d80eb916dd6beecbd1fb949 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 52 68 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_04700 c7d2ba2ca9cfb4a0ae59cbee82529b7b 65 Pfam PF02597 ThiS family 4 65 1.6E-15 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFR_04700 c7d2ba2ca9cfb4a0ae59cbee82529b7b 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 65 1.7E-19 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis AFR_04700 c7d2ba2ca9cfb4a0ae59cbee82529b7b 65 SUPERFAMILY SSF54285 3 64 2.04E-16 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFR_04700 c7d2ba2ca9cfb4a0ae59cbee82529b7b 65 Gene3D G3DSA:3.10.20.30 1 65 1.2E-23 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_36145 8799892c63ad817984a7aff0cf43d01d 419 Pfam PF13180 PDZ domain 169 226 9.3E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFR_36145 8799892c63ad817984a7aff0cf43d01d 419 Pfam PF02163 Peptidase family M50 9 367 2.7E-47 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFR_36145 8799892c63ad817984a7aff0cf43d01d 419 Gene3D G3DSA:2.30.42.10 151 233 1.6E-11 T 12-10-2018 AFR_36145 8799892c63ad817984a7aff0cf43d01d 419 SUPERFAMILY SSF50156 171 231 1.6E-10 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFR_10695 fa108f09a48d29287a26bc1e388652b5 159 SUPERFAMILY SSF117916 53 153 5.89E-27 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFR_10695 fa108f09a48d29287a26bc1e388652b5 159 Gene3D G3DSA:3.30.300.130 49 154 1.4E-30 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFR_10695 fa108f09a48d29287a26bc1e388652b5 159 Pfam PF01883 Iron-sulfur cluster assembly protein 57 122 3.9E-20 T 12-10-2018 IPR002744 MIP18 family-like AFR_32920 491b1996f8498b2f196c46fa99a8d7f6 264 SUPERFAMILY SSF48452 117 227 3.79E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32920 491b1996f8498b2f196c46fa99a8d7f6 264 Gene3D G3DSA:1.25.40.10 82 231 2.6E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_39570 e12b4fdf0fc36cf8441b07ef36129aeb 237 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 101 5.0E-9 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFR_39570 e12b4fdf0fc36cf8441b07ef36129aeb 237 SUPERFAMILY SSF53927 4 127 4.7E-38 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFR_39570 e12b4fdf0fc36cf8441b07ef36129aeb 237 Gene3D G3DSA:3.40.140.10 1 130 8.8E-47 T 12-10-2018 AFR_26545 63bb8e50d924ac8dc3e967773db9cb12 201 PIRSF PIRSF006324 2 199 3.9E-45 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_26545 63bb8e50d924ac8dc3e967773db9cb12 201 Pfam PF01810 LysE type translocator 17 198 1.2E-32 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_39360 044d8eb7fed357855de6dafee95455fb 375 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 57 67 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_39360 044d8eb7fed357855de6dafee95455fb 375 PRINTS PR00723 Subtilisin serine protease family (S8) signature 52 71 1.5E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_39360 044d8eb7fed357855de6dafee95455fb 375 PRINTS PR00723 Subtilisin serine protease family (S8) signature 90 103 1.5E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_39360 044d8eb7fed357855de6dafee95455fb 375 PRINTS PR00723 Subtilisin serine protease family (S8) signature 243 259 1.5E-12 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_39360 044d8eb7fed357855de6dafee95455fb 375 Pfam PF00082 Subtilase family 52 294 5.1E-40 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_39360 044d8eb7fed357855de6dafee95455fb 375 SUPERFAMILY SSF52743 35 303 3.53E-75 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_39360 044d8eb7fed357855de6dafee95455fb 375 Gene3D G3DSA:3.40.50.200 11 305 8.2E-82 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_24535 a96c66bc584301c1ef674efbeccf0699 119 Pfam PF12680 SnoaL-like domain 21 109 1.0E-10 T 12-10-2018 IPR037401 SnoaL-like domain AFR_24535 a96c66bc584301c1ef674efbeccf0699 119 SUPERFAMILY SSF54427 11 115 4.49E-22 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_24535 a96c66bc584301c1ef674efbeccf0699 119 Gene3D G3DSA:3.10.450.50 6 117 7.7E-26 T 12-10-2018 AFR_21230 9cc4fef9823f674751c20c376f4b6604 218 Gene3D G3DSA:3.40.50.150 19 205 6.0E-35 T 12-10-2018 AFR_21230 9cc4fef9823f674751c20c376f4b6604 218 Pfam PF13649 Methyltransferase domain 64 156 5.8E-13 T 12-10-2018 AFR_21230 9cc4fef9823f674751c20c376f4b6604 218 SUPERFAMILY SSF53335 20 200 2.87E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_17150 72ad825313e7935f6b492a6527f71e44 343 Pfam PF13407 Periplasmic binding protein domain 47 302 1.8E-45 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_17150 72ad825313e7935f6b492a6527f71e44 343 SUPERFAMILY SSF53822 44 325 1.16E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_17150 72ad825313e7935f6b492a6527f71e44 343 Gene3D G3DSA:3.40.50.2300 150 284 1.3E-64 T 12-10-2018 AFR_17150 72ad825313e7935f6b492a6527f71e44 343 Gene3D G3DSA:3.40.50.2300 49 303 1.3E-64 T 12-10-2018 AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 5 249 3.9E-114 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 PIRSF PIRSF000709 1 113 2.3E-4 T 12-10-2018 AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 PIRSF PIRSF000709 149 215 2.7 T 12-10-2018 AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 SMART SM00855 5 191 9.9E-24 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 SUPERFAMILY SSF53254 5 224 1.16E-70 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 Gene3D G3DSA:3.40.50.1240 4 249 1.7E-80 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 3 232 42.675 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 AFR_40285 1afb61bd992a048f65cd8c7bbad51f65 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 210 4.5E-29 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_34840 2fc43b530de6d0f2810179f5a04abfc1 205 Gene3D G3DSA:3.30.1360.40 1 75 1.4E-20 T 12-10-2018 AFR_34840 2fc43b530de6d0f2810179f5a04abfc1 205 Gene3D G3DSA:2.40.100.10 76 204 2.2E-56 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_34840 2fc43b530de6d0f2810179f5a04abfc1 205 SUPERFAMILY SSF160467 3 85 1.14E-12 T 12-10-2018 AFR_34840 2fc43b530de6d0f2810179f5a04abfc1 205 SUPERFAMILY SSF50891 81 204 6.83E-42 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_34840 2fc43b530de6d0f2810179f5a04abfc1 205 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 3 192 2.9E-69 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D AFR_34840 2fc43b530de6d0f2810179f5a04abfc1 205 SMART SM00796 2 192 2.2E-94 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 SMART SM00345 17 76 2.1E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 7.9E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 Gene3D G3DSA:3.40.640.10 130 341 8.0E-57 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 Gene3D G3DSA:1.10.10.10 15 88 6.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 SUPERFAMILY SSF46785 16 90 1.88E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 Pfam PF00155 Aminotransferase class I and II 101 433 2.4E-24 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 Gene3D G3DSA:3.90.1150.10 101 424 8.0E-57 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_27545 5d6d5f3500b8d071e7129a1c60e42f59 458 SUPERFAMILY SSF53383 99 438 3.1E-63 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_28130 b6bd6a392d2ea90a43aa01b0eeca083f 104 Pfam PF05331 Protein of unknown function (DUF742) 1 85 8.7E-22 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_30305 8356f29a8e3061b42fd317ec8da2048c 301 Gene3D G3DSA:3.40.50.300 1 248 1.1E-52 T 12-10-2018 AFR_30305 8356f29a8e3061b42fd317ec8da2048c 301 Pfam PF00005 ABC transporter 18 156 2.9E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_30305 8356f29a8e3061b42fd317ec8da2048c 301 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_30305 8356f29a8e3061b42fd317ec8da2048c 301 SMART SM00382 26 204 1.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_30305 8356f29a8e3061b42fd317ec8da2048c 301 SUPERFAMILY SSF52540 2 216 6.88E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 SUPERFAMILY SSF46785 16 82 3.09E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 SUPERFAMILY SSF53067 87 362 9.98E-34 T 12-10-2018 AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 43 2.8E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 16 32 2.8E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 62 2.8E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 Pfam PF00480 ROK family 99 248 5.0E-17 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 Gene3D G3DSA:3.30.420.40 212 343 1.4E-38 T 12-10-2018 AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 Gene3D G3DSA:3.30.420.40 90 355 1.4E-38 T 12-10-2018 AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 Gene3D G3DSA:1.10.10.10 8 81 1.3E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33955 04a5fc92cfd706ced4ccb96063fb9790 370 Pfam PF13412 Winged helix-turn-helix DNA-binding 18 62 1.5E-10 T 12-10-2018 AFR_42210 218ec940ab76110671047231828179a3 176 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 42 171 4.4E-38 T 12-10-2018 IPR005247 YbhB/YbcL AFR_42210 218ec940ab76110671047231828179a3 176 Gene3D G3DSA:3.90.280.10 5 174 3.2E-52 T 12-10-2018 IPR036610 PEBP-like superfamily AFR_42210 218ec940ab76110671047231828179a3 176 SUPERFAMILY SSF49777 9 166 1.1E-46 T 12-10-2018 IPR036610 PEBP-like superfamily AFR_42210 218ec940ab76110671047231828179a3 176 Pfam PF01161 Phosphatidylethanolamine-binding protein 41 172 4.0E-37 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 4 300 3.0E-109 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 Pfam PF11762 L-arabinose isomerase C-terminal domain 358 471 2.8E-45 T 12-10-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 PIRSF PIRSF001478 1 495 9.7E-227 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 SUPERFAMILY SSF50443 325 492 3.4E-66 T 12-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 Hamap MF_00519 L-arabinose isomerase [araA]. 1 472 61.773 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 Pfam PF02610 L-arabinose isomerase 3 355 1.4E-171 T 12-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 SUPERFAMILY SSF53743 2 321 2.75E-114 T 12-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 AFR_25540 a7018d3c68c465b2ea1e183ba6855944 496 Gene3D G3DSA:3.40.50.10940 1 171 9.4E-77 T 12-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 AFR_11335 265561aad287e6b9bda61c4c2370f029 137 Pfam PF01047 MarR family 31 88 1.8E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11335 265561aad287e6b9bda61c4c2370f029 137 Gene3D G3DSA:1.10.10.10 4 135 2.5E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11335 265561aad287e6b9bda61c4c2370f029 137 SMART SM00347 24 122 4.4E-21 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11335 265561aad287e6b9bda61c4c2370f029 137 SUPERFAMILY SSF46785 3 135 3.52E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11335 265561aad287e6b9bda61c4c2370f029 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 3.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11335 265561aad287e6b9bda61c4c2370f029 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 3.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11335 265561aad287e6b9bda61c4c2370f029 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 3.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_00485 a524db0bfb81a274902cd75fee23face 326 Gene3D G3DSA:3.40.50.920 201 322 2.2E-43 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_00485 a524db0bfb81a274902cd75fee23face 326 Pfam PF02779 Transketolase, pyrimidine binding domain 5 178 9.0E-48 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_00485 a524db0bfb81a274902cd75fee23face 326 SUPERFAMILY SSF52922 191 325 1.96E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_00485 a524db0bfb81a274902cd75fee23face 326 SMART SM00861 5 180 2.0E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFR_00485 a524db0bfb81a274902cd75fee23face 326 SUPERFAMILY SSF52518 4 191 2.16E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_00485 a524db0bfb81a274902cd75fee23face 326 Pfam PF02780 Transketolase, C-terminal domain 198 316 8.3E-36 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFR_00485 a524db0bfb81a274902cd75fee23face 326 Gene3D G3DSA:3.40.50.970 1 200 8.8E-78 T 12-10-2018 AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 SUPERFAMILY SSF46785 22 152 2.96E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 Gene3D G3DSA:1.10.10.10 4 156 1.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 2.0E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 117 2.0E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 97 2.0E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 81 2.0E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 Pfam PF12802 MarR family 44 105 1.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_32320 0f4ff417a8ba96a7289d862696a0a43b 156 SMART SM00347 38 141 6.4E-21 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 Gene3D G3DSA:3.40.980.10 172 324 3.8E-72 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 SUPERFAMILY SSF63882 10 170 2.88E-32 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 Pfam PF03454 MoeA C-terminal region (domain IV) 333 400 4.7E-11 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 SMART SM00852 176 321 4.9E-23 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 SUPERFAMILY SSF63867 331 400 4.84E-9 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 Gene3D G3DSA:2.40.340.10 331 397 8.3E-7 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 Pfam PF03453 MoeA N-terminal region (domain I and II) 23 163 1.1E-28 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 Gene3D G3DSA:3.90.105.10 30 171 3.8E-72 T 12-10-2018 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 Gene3D G3DSA:2.170.190.11 52 137 3.8E-72 T 12-10-2018 AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 Pfam PF00994 Probable molybdopterin binding domain 177 319 2.4E-15 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_42725 0c3e2c51e70d80fd7bb0538c463ed543 408 SUPERFAMILY SSF53218 173 324 2.62E-25 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_00855 e7f078064ed5381a5edd5be10c71f9d3 127 Gene3D G3DSA:3.30.70.1060 1 124 1.6E-39 T 12-10-2018 AFR_00855 e7f078064ed5381a5edd5be10c71f9d3 127 Pfam PF03795 YCII-related domain 5 122 6.6E-22 T 12-10-2018 IPR005545 YCII-related AFR_00855 e7f078064ed5381a5edd5be10c71f9d3 127 SUPERFAMILY SSF54909 3 122 1.18E-28 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_32740 0d5a21831f8f135bd209ab1a6865828d 138 Pfam PF07883 Cupin domain 54 119 9.5E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_32740 0d5a21831f8f135bd209ab1a6865828d 138 Gene3D G3DSA:2.60.120.10 18 132 2.3E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_32740 0d5a21831f8f135bd209ab1a6865828d 138 SUPERFAMILY SSF51182 20 134 2.83E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_32900 22e523e596e95a9a070a310ec0e387d2 474 SUPERFAMILY SSF53474 35 225 1.77E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32900 22e523e596e95a9a070a310ec0e387d2 474 Pfam PF12146 Serine aminopeptidase, S33 40 153 1.7E-15 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFR_32900 22e523e596e95a9a070a310ec0e387d2 474 Gene3D G3DSA:3.40.50.1820 24 224 2.5E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_05555 7e8ac998db2888d5bf464db365e0b304 165 SMART SM01001 3 152 1.6E-95 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFR_05555 7e8ac998db2888d5bf464db365e0b304 165 Pfam PF00731 AIR carboxylase 5 149 5.9E-65 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFR_05555 7e8ac998db2888d5bf464db365e0b304 165 SUPERFAMILY SSF52255 3 161 4.71E-65 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFR_05555 7e8ac998db2888d5bf464db365e0b304 165 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 31.606 T 12-10-2018 IPR033747 Class I PurE AFR_05555 7e8ac998db2888d5bf464db365e0b304 165 PIRSF PIRSF001338 1 163 1.1E-66 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AFR_05555 7e8ac998db2888d5bf464db365e0b304 165 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 5.5E-66 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFR_05555 7e8ac998db2888d5bf464db365e0b304 165 Gene3D G3DSA:3.40.50.7700 1 164 3.8E-73 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFR_24795 90f9318051c38add1dd610ba0a48a686 1196 SUPERFAMILY SSF63829 1076 1171 1.24E-8 T 12-10-2018 AFR_24795 90f9318051c38add1dd610ba0a48a686 1196 SUPERFAMILY SSF50998 727 1038 7.77E-26 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_24795 90f9318051c38add1dd610ba0a48a686 1196 Gene3D G3DSA:2.130.10.10 940 1180 6.2E-16 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_24795 90f9318051c38add1dd610ba0a48a686 1196 Gene3D G3DSA:2.130.10.10 639 928 4.2E-16 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_24795 90f9318051c38add1dd610ba0a48a686 1196 SUPERFAMILY SSF69322 595 796 4.97E-10 T 12-10-2018 AFR_35710 c01359204f33b86e928f184448d3de5e 351 SUPERFAMILY SSF54631 212 343 9.1E-22 T 12-10-2018 AFR_35710 c01359204f33b86e928f184448d3de5e 351 Pfam PF00571 CBS domain 218 271 0.0011 T 12-10-2018 IPR000644 CBS domain AFR_35710 c01359204f33b86e928f184448d3de5e 351 SMART SM00116 287 334 3.1 T 12-10-2018 IPR000644 CBS domain AFR_35710 c01359204f33b86e928f184448d3de5e 351 SMART SM00116 226 274 1.7 T 12-10-2018 IPR000644 CBS domain AFR_35710 c01359204f33b86e928f184448d3de5e 351 Gene3D G3DSA:3.10.580.10 200 342 4.6E-25 T 12-10-2018 AFR_35710 c01359204f33b86e928f184448d3de5e 351 Pfam PF01595 Domain of unknown function DUF21 9 201 2.3E-39 T 12-10-2018 IPR002550 CNNM, transmembrane domain AFR_12420 dd5b8636a6dc008de9573169063fada9 407 PRINTS PR01035 Tetracycline resistance protein signature 47 66 1.0E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_12420 dd5b8636a6dc008de9573169063fada9 407 PRINTS PR01035 Tetracycline resistance protein signature 169 189 1.0E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_12420 dd5b8636a6dc008de9573169063fada9 407 PRINTS PR01035 Tetracycline resistance protein signature 343 366 1.0E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_12420 dd5b8636a6dc008de9573169063fada9 407 PRINTS PR01035 Tetracycline resistance protein signature 141 163 1.0E-9 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_12420 dd5b8636a6dc008de9573169063fada9 407 SUPERFAMILY SSF103473 8 390 8.63E-42 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_12420 dd5b8636a6dc008de9573169063fada9 407 Gene3D G3DSA:1.20.1250.20 5 392 2.2E-39 T 12-10-2018 AFR_12420 dd5b8636a6dc008de9573169063fada9 407 Pfam PF05977 Transmembrane secretion effector 2 393 5.0E-26 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_10825 379ea8feb380057ea34b0e6d17793529 196 Gene3D G3DSA:3.30.530.20 7 176 4.9E-39 T 12-10-2018 IPR023393 START-like domain superfamily AFR_10825 379ea8feb380057ea34b0e6d17793529 196 SUPERFAMILY SSF55961 24 154 2.55E-31 T 12-10-2018 AFR_10825 379ea8feb380057ea34b0e6d17793529 196 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 137 6.4E-13 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_20685 840f52968cd4906553733f79822fced7 317 SUPERFAMILY SSF53613 5 309 2.03E-76 T 12-10-2018 IPR029056 Ribokinase-like AFR_20685 840f52968cd4906553733f79822fced7 317 Gene3D G3DSA:3.40.1190.20 7 292 4.9E-97 T 12-10-2018 IPR029056 Ribokinase-like AFR_20685 840f52968cd4906553733f79822fced7 317 Gene3D G3DSA:2.20.150.10 12 107 4.9E-97 T 12-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 AFR_20685 840f52968cd4906553733f79822fced7 317 Pfam PF00294 pfkB family carbohydrate kinase 6 302 4.5E-53 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_20685 840f52968cd4906553733f79822fced7 317 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 5 310 6.2E-116 T 12-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 SUPERFAMILY SSF47203 279 433 7.09E-41 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 170 264 2.4E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 172 184 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 274 430 2.0E-31 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 SUPERFAMILY SSF56645 47 283 1.15E-37 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 389 408 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 Gene3D G3DSA:2.40.110.20 120 273 3.5E-57 T 12-10-2018 AFR_25910 d6c06b112230fe8dfa53d966f2cebec5 535 Gene3D G3DSA:1.20.140.10 274 431 6.7E-37 T 12-10-2018 AFR_23385 e355ed90a4576d9e15c2b12cdb6eb733 129 Pfam PF13581 Histidine kinase-like ATPase domain 14 116 1.1E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_23385 e355ed90a4576d9e15c2b12cdb6eb733 129 Gene3D G3DSA:3.30.565.10 4 128 5.7E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_23385 e355ed90a4576d9e15c2b12cdb6eb733 129 SUPERFAMILY SSF55874 3 121 1.58E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_39630 545a00747fa0028abe906ccdc86c55ac 325 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 323 7.3E-111 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 AFR_39630 545a00747fa0028abe906ccdc86c55ac 325 Gene3D G3DSA:3.90.25.10 171 305 1.7E-110 T 12-10-2018 AFR_39630 545a00747fa0028abe906ccdc86c55ac 325 SUPERFAMILY SSF51735 2 323 5.63E-88 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_39630 545a00747fa0028abe906ccdc86c55ac 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 252 4.5E-50 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_39630 545a00747fa0028abe906ccdc86c55ac 325 Gene3D G3DSA:3.40.50.720 4 252 1.7E-110 T 12-10-2018 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 PIRSF PIRSF001112 1 357 1.6E-103 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 Gene3D G3DSA:3.40.50.1820 1 359 8.8E-137 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20175 116047ed01d2d823552fd3b6573f5542 364 PRINTS PR00412 Epoxide hydrolase signature 330 352 4.2E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 PRINTS PR00412 Epoxide hydrolase signature 178 191 4.2E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 PRINTS PR00412 Epoxide hydrolase signature 299 315 4.2E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 PRINTS PR00412 Epoxide hydrolase signature 164 177 4.2E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 PRINTS PR00412 Epoxide hydrolase signature 100 118 4.2E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 Pfam PF06441 Epoxide hydrolase N terminus 4 109 4.4E-36 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_20175 116047ed01d2d823552fd3b6573f5542 364 SUPERFAMILY SSF53474 3 354 5.46E-98 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20040 7af7137e9dec24dcc6db2623a1d55ef8 293 SUPERFAMILY SSF51717 15 282 8.37E-85 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_20040 7af7137e9dec24dcc6db2623a1d55ef8 293 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 28 43 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_20040 7af7137e9dec24dcc6db2623a1d55ef8 293 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 28 280 1.4E-80 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 AFR_20040 7af7137e9dec24dcc6db2623a1d55ef8 293 Gene3D G3DSA:3.20.20.20 17 292 2.7E-90 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_20040 7af7137e9dec24dcc6db2623a1d55ef8 293 Pfam PF00809 Pterin binding enzyme 29 265 7.3E-67 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 9.8E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 SUPERFAMILY SSF52172 2 133 2.42E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 Pfam PF00072 Response regulator receiver domain 4 116 5.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 Gene3D G3DSA:3.40.50.12740 2 214 3.3E-72 T 12-10-2018 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 SMART SM00421 151 208 2.2E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 3.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 3.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 3.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 SUPERFAMILY SSF46894 138 214 7.48E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_11030 aa3c29e91eb6adc478d05d79004fccdb 218 SMART SM00448 2 115 2.2E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20100 7b6f51e0138431713b4eb001f1df0bf5 171 Gene3D G3DSA:3.40.630.30 1 170 3.5E-47 T 12-10-2018 AFR_20100 7b6f51e0138431713b4eb001f1df0bf5 171 Pfam PF13508 Acetyltransferase (GNAT) domain 62 144 1.2E-10 T 12-10-2018 IPR000182 GNAT domain AFR_20100 7b6f51e0138431713b4eb001f1df0bf5 171 SUPERFAMILY SSF55729 3 170 3.43E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 Gene3D G3DSA:1.10.1740.10 2 77 5.8E-9 T 12-10-2018 AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 156 5.6E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 Pfam PF04542 Sigma-70 region 2 16 79 2.1E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 SUPERFAMILY SSF88946 9 88 3.81E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 Pfam PF08281 Sigma-70, region 4 101 154 2.1E-18 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 Gene3D G3DSA:1.10.10.10 78 160 3.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 SUPERFAMILY SSF88659 84 160 6.35E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_00350 1bde94286957ee3dcbae5edd6141d363 173 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 9 159 3.4E-47 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_02755 4b022f66933631881385f66d6bdf8243 442 Gene3D G3DSA:1.20.1250.20 9 387 1.9E-43 T 12-10-2018 AFR_02755 4b022f66933631881385f66d6bdf8243 442 SUPERFAMILY SSF103473 10 386 1.57E-42 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_02755 4b022f66933631881385f66d6bdf8243 442 Pfam PF07690 Major Facilitator Superfamily 19 233 4.4E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_40465 38add5d2216bb47ae597749b8bee1ccc 657 Pfam PF02120 Flagellar hook-length control protein FliK 533 609 2.4E-15 T 12-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal AFR_40465 38add5d2216bb47ae597749b8bee1ccc 657 Gene3D G3DSA:3.30.750.140 508 616 2.7E-14 T 12-10-2018 IPR038610 FliK-like, C-terminal domain superfamily AFR_06535 b65c804d259db40524e3c03e34606972 532 Gene3D G3DSA:3.40.50.150 1 200 6.8E-37 T 12-10-2018 AFR_06535 b65c804d259db40524e3c03e34606972 532 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 191 1.3E-15 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFR_06535 b65c804d259db40524e3c03e34606972 532 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 4 20 4.4E-7 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFR_06535 b65c804d259db40524e3c03e34606972 532 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 129 143 4.4E-7 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFR_06535 b65c804d259db40524e3c03e34606972 532 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 177 190 4.4E-7 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFR_06535 b65c804d259db40524e3c03e34606972 532 SUPERFAMILY SSF53335 3 521 3.03E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_32005 3cf8a6bc18ff1729e0973d1aae323986 194 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 3 94 8.1E-14 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_32005 3cf8a6bc18ff1729e0973d1aae323986 194 SUPERFAMILY SSF109854 4 120 2.75E-16 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_32005 3cf8a6bc18ff1729e0973d1aae323986 194 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 3 181 1.0E-27 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_32005 3cf8a6bc18ff1729e0973d1aae323986 194 Gene3D G3DSA:1.20.120.450 1 117 4.2E-11 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_01040 589e70757f4705774cb89b7331210b47 146 SUPERFAMILY SSF54909 1 121 9.38E-28 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_01040 589e70757f4705774cb89b7331210b47 146 Pfam PF03795 YCII-related domain 1 110 2.2E-16 T 12-10-2018 IPR005545 YCII-related AFR_01040 589e70757f4705774cb89b7331210b47 146 Gene3D G3DSA:3.30.70.1060 1 121 1.5E-26 T 12-10-2018 AFR_01990 0244229192335fde5285547673d4779f 188 SUPERFAMILY SSF48498 105 184 1.33E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_01990 0244229192335fde5285547673d4779f 188 Gene3D G3DSA:1.10.357.10 7 187 1.6E-53 T 12-10-2018 AFR_01990 0244229192335fde5285547673d4779f 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01990 0244229192335fde5285547673d4779f 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01990 0244229192335fde5285547673d4779f 188 SUPERFAMILY SSF46689 6 87 9.23E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01990 0244229192335fde5285547673d4779f 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 7.4E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 Gene3D G3DSA:3.40.1190.20 6 292 7.5E-56 T 12-10-2018 IPR029056 Ribokinase-like AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 SUPERFAMILY SSF53613 1 287 4.83E-51 T 12-10-2018 IPR029056 Ribokinase-like AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 PRINTS PR00990 Ribokinase signature 174 189 2.5E-11 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 PRINTS PR00990 Ribokinase signature 8 29 2.5E-11 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 PRINTS PR00990 Ribokinase signature 35 54 2.5E-11 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 Pfam PF00294 pfkB family carbohydrate kinase 8 285 1.8E-31 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 40 64 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_34985 73c85e2093fd574f9a61f85113f2f5bd 296 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 241 254 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_20980 07ad828209d50d215e533f2294ee2540 229 Gene3D G3DSA:3.30.20.10 90 150 1.6E-84 T 12-10-2018 AFR_20980 07ad828209d50d215e533f2294ee2540 229 Pfam PF00182 Chitinase class I 41 229 1.2E-43 T 12-10-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_20980 07ad828209d50d215e533f2294ee2540 229 Gene3D G3DSA:1.10.530.10 31 229 1.6E-84 T 12-10-2018 AFR_20980 07ad828209d50d215e533f2294ee2540 229 SUPERFAMILY SSF53955 27 229 1.88E-67 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_20980 07ad828209d50d215e533f2294ee2540 229 PIRSF PIRSF001060 3 229 1.1E-81 T 12-10-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_08620 55ada07dfbc03680ed3713a47d88ca1a 186 SUPERFAMILY SSF46689 2 57 1.3E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_08620 55ada07dfbc03680ed3713a47d88ca1a 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 7.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_08620 55ada07dfbc03680ed3713a47d88ca1a 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 7.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_08620 55ada07dfbc03680ed3713a47d88ca1a 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 50 1.1E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_08620 55ada07dfbc03680ed3713a47d88ca1a 186 Gene3D G3DSA:1.10.357.10 1 186 2.5E-57 T 12-10-2018 AFR_08620 55ada07dfbc03680ed3713a47d88ca1a 186 Pfam PF16925 Bacterial transcriptional repressor C-terminal 70 182 2.0E-19 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_08620 55ada07dfbc03680ed3713a47d88ca1a 186 SUPERFAMILY SSF48498 70 182 3.34E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_19655 f6b63f7ce91ef55275789bc9a50d5538 118 Gene3D G3DSA:3.30.70.1060 1 118 2.0E-36 T 12-10-2018 AFR_19655 f6b63f7ce91ef55275789bc9a50d5538 118 Pfam PF03795 YCII-related domain 3 115 4.4E-18 T 12-10-2018 IPR005545 YCII-related AFR_19655 f6b63f7ce91ef55275789bc9a50d5538 118 SUPERFAMILY SSF54909 3 115 2.14E-26 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_24025 e23d14d599477640b86ca88d1b4e8894 133 Pfam PF09350 Domain of unknown function (DUF1992) 9 76 1.1E-21 T 12-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain AFR_30340 cef1957deabeabfafd08e91e71941650 435 Gene3D G3DSA:3.40.50.450 72 263 8.7E-60 T 12-10-2018 AFR_30340 cef1957deabeabfafd08e91e71941650 435 PIRSF PIRSF000534 3 434 2.1E-160 T 12-10-2018 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFR_30340 cef1957deabeabfafd08e91e71941650 435 Hamap MF_01981 ATP-dependent 6-phosphofructokinase [pfkA]. 5 433 50.851 T 12-10-2018 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFR_30340 cef1957deabeabfafd08e91e71941650 435 Pfam PF00365 Phosphofructokinase 78 381 8.5E-64 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_30340 cef1957deabeabfafd08e91e71941650 435 SUPERFAMILY SSF53784 60 431 3.27E-118 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_30340 cef1957deabeabfafd08e91e71941650 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 200 217 5.5E-25 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_30340 cef1957deabeabfafd08e91e71941650 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 255 5.5E-25 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_30340 cef1957deabeabfafd08e91e71941650 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 293 305 5.5E-25 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_30340 cef1957deabeabfafd08e91e71941650 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 167 183 5.5E-25 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_30340 cef1957deabeabfafd08e91e71941650 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 218 236 5.5E-25 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_30340 cef1957deabeabfafd08e91e71941650 435 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 80 99 5.5E-25 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFR_08010 01d982bec64b3502d58ba89072031b8b 219 Pfam PF12710 haloacid dehalogenase-like hydrolase 2 175 1.1E-10 T 12-10-2018 AFR_08010 01d982bec64b3502d58ba89072031b8b 219 Gene3D G3DSA:1.10.150.240 13 77 4.1E-43 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_08010 01d982bec64b3502d58ba89072031b8b 219 Gene3D G3DSA:3.40.50.1000 1 203 4.1E-43 T 12-10-2018 IPR023214 HAD superfamily AFR_08010 01d982bec64b3502d58ba89072031b8b 219 SUPERFAMILY SSF56784 2 213 1.41E-24 T 12-10-2018 IPR036412 HAD-like superfamily AFR_37590 108709aadf64e88cb44b476b2b81666f 214 SMART SM00862 142 211 5.6E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_37590 108709aadf64e88cb44b476b2b81666f 214 Pfam PF00072 Response regulator receiver domain 1 109 7.5E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_37590 108709aadf64e88cb44b476b2b81666f 214 SUPERFAMILY SSF52172 1 115 2.7E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_37590 108709aadf64e88cb44b476b2b81666f 214 Gene3D G3DSA:3.40.50.2300 1 118 2.2E-34 T 12-10-2018 AFR_37590 108709aadf64e88cb44b476b2b81666f 214 SMART SM00448 1 109 4.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_37590 108709aadf64e88cb44b476b2b81666f 214 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 211 1.2E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_37590 108709aadf64e88cb44b476b2b81666f 214 SUPERFAMILY SSF46894 126 211 3.4E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_37590 108709aadf64e88cb44b476b2b81666f 214 Gene3D G3DSA:1.10.10.10 119 213 8.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26640 8fa96442e2742fc7cd430ab7c7cdcdef 200 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 196 3.0E-68 T 12-10-2018 IPR021441 Protein of unknown function DUF3090 AFR_26640 8fa96442e2742fc7cd430ab7c7cdcdef 200 Pfam PF11290 Protein of unknown function (DUF3090) 6 192 1.0E-68 T 12-10-2018 IPR021441 Protein of unknown function DUF3090 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 PIRSF PIRSF000343 2 213 3.0E-56 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 Pfam PF01126 Heme oxygenase 9 207 6.1E-42 T 12-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 PRINTS PR00088 Haem oxygenase signature 44 69 7.3E-21 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 PRINTS PR00088 Haem oxygenase signature 9 34 7.3E-21 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 PRINTS PR00088 Haem oxygenase signature 120 141 7.3E-21 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 PRINTS PR00088 Haem oxygenase signature 193 211 7.3E-21 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 PRINTS PR00088 Haem oxygenase signature 69 94 7.3E-21 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 Gene3D G3DSA:1.20.910.10 7 213 3.4E-57 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_04095 1fd9085883bab0a28a366c80b079077c 213 SUPERFAMILY SSF48613 10 210 2.92E-48 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_13990 b88ae7ef6a77901411982c209191fa50 290 Gene3D G3DSA:1.10.3720.10 73 282 2.4E-21 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13990 b88ae7ef6a77901411982c209191fa50 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 285 1.6E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_13990 b88ae7ef6a77901411982c209191fa50 290 SUPERFAMILY SSF161098 78 265 1.21E-24 T 12-10-2018 IPR035906 MetI-like superfamily AFR_29905 2583d6a49049f81b9c2b6c462a3250b7 376 Gene3D G3DSA:3.40.50.2000 176 347 3.9E-38 T 12-10-2018 AFR_29905 2583d6a49049f81b9c2b6c462a3250b7 376 Pfam PF00534 Glycosyl transferases group 1 188 345 1.5E-23 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_29905 2583d6a49049f81b9c2b6c462a3250b7 376 Gene3D G3DSA:3.40.50.2000 12 174 3.8E-16 T 12-10-2018 AFR_29905 2583d6a49049f81b9c2b6c462a3250b7 376 SUPERFAMILY SSF53756 18 366 8.46E-59 T 12-10-2018 AFR_29905 2583d6a49049f81b9c2b6c462a3250b7 376 Pfam PF13579 Glycosyl transferase 4-like domain 21 167 4.8E-18 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_38925 5105aed9462c232c3c313655840da2d2 206 SMART SM00421 140 197 1.6E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38925 5105aed9462c232c3c313655840da2d2 206 Gene3D G3DSA:3.40.50.2300 17 140 1.8E-15 T 12-10-2018 AFR_38925 5105aed9462c232c3c313655840da2d2 206 SMART SM00448 18 124 9.3E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_38925 5105aed9462c232c3c313655840da2d2 206 SUPERFAMILY SSF46894 132 202 7.48E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_38925 5105aed9462c232c3c313655840da2d2 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 8.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38925 5105aed9462c232c3c313655840da2d2 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 8.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38925 5105aed9462c232c3c313655840da2d2 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 8.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38925 5105aed9462c232c3c313655840da2d2 206 Pfam PF00072 Response regulator receiver domain 22 122 2.2E-10 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_38925 5105aed9462c232c3c313655840da2d2 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 195 8.6E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38925 5105aed9462c232c3c313655840da2d2 206 Gene3D G3DSA:1.10.10.10 141 199 2.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38925 5105aed9462c232c3c313655840da2d2 206 SUPERFAMILY SSF52172 19 130 4.84E-15 T 12-10-2018 IPR011006 CheY-like superfamily AFR_18485 8556c03241df8361e3c77e530e4dbdfe 407 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 268 275 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFR_18485 8556c03241df8361e3c77e530e4dbdfe 407 SUPERFAMILY SSF51735 11 96 9.25E-5 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_18485 8556c03241df8361e3c77e530e4dbdfe 407 Gene3D G3DSA:3.30.470.20 101 397 3.3E-70 T 12-10-2018 AFR_18485 8556c03241df8361e3c77e530e4dbdfe 407 SUPERFAMILY SSF56059 107 311 3.71E-41 T 12-10-2018 AFR_18485 8556c03241df8361e3c77e530e4dbdfe 407 Pfam PF13535 ATP-grasp domain 144 278 5.7E-15 T 12-10-2018 AFR_18485 8556c03241df8361e3c77e530e4dbdfe 407 SMART SM01209 108 276 0.0018 T 12-10-2018 AFR_11290 de10a862f055d7fdaed17e8525a080d8 273 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 252 5.2E-31 T 12-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase AFR_38560 7e4671357c1d289a883dd985e527e531 172 Gene3D G3DSA:3.40.50.300 4 170 4.1E-30 T 12-10-2018 AFR_38560 7e4671357c1d289a883dd985e527e531 172 Pfam PF13671 AAA domain 5 132 3.4E-13 T 12-10-2018 AFR_38560 7e4671357c1d289a883dd985e527e531 172 SUPERFAMILY SSF52540 5 155 8.31E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19540 3780d61e66aa845f13c678ca40ab3905 240 Gene3D G3DSA:1.10.1760.20 6 212 3.2E-54 T 12-10-2018 AFR_19540 3780d61e66aa845f13c678ca40ab3905 240 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 7 213 6.4E-53 T 12-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 AFR_21495 d16de76eb8e94608694c82713c692998 164 SUPERFAMILY SSF55729 41 151 9.04E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_21495 d16de76eb8e94608694c82713c692998 164 Pfam PF13302 Acetyltransferase (GNAT) domain 49 143 3.9E-15 T 12-10-2018 IPR000182 GNAT domain AFR_21495 d16de76eb8e94608694c82713c692998 164 Gene3D G3DSA:3.40.630.30 8 161 2.5E-23 T 12-10-2018 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 Gene3D G3DSA:1.20.200.10 96 351 2.6E-69 T 12-10-2018 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 SMART SM00998 354 433 3.9E-21 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 ProSitePatterns PS00163 Fumarate lyases signature. 266 275 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 Pfam PF10397 Adenylosuccinate lyase C-terminus 355 429 5.9E-18 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.3E-17 T 12-10-2018 IPR000362 Fumarate lyase family AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 1.3E-17 T 12-10-2018 IPR000362 Fumarate lyase family AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 PRINTS PR00149 Fumarate lyase superfamily signature 266 282 1.3E-17 T 12-10-2018 IPR000362 Fumarate lyase family AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 PRINTS PR00149 Fumarate lyase superfamily signature 221 248 1.3E-17 T 12-10-2018 IPR000362 Fumarate lyase family AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 Gene3D G3DSA:1.10.40.30 353 440 1.1E-23 T 12-10-2018 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 Pfam PF00206 Lyase 19 289 7.3E-39 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 PRINTS PR00145 Argininosuccinate lyase family signature 221 245 1.4E-9 T 12-10-2018 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 PRINTS PR00145 Argininosuccinate lyase family signature 266 282 1.4E-9 T 12-10-2018 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 1.4E-9 T 12-10-2018 AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 Gene3D G3DSA:1.10.275.10 5 95 7.4E-25 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_14120 3c66b2b47883d2e158706cc85ddd3c3f 443 SUPERFAMILY SSF48557 11 431 2.2E-94 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_34425 661db9456e13634e1a875237aa4df7e7 235 SUPERFAMILY SSF53056 35 234 2.22E-51 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_34425 661db9456e13634e1a875237aa4df7e7 235 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 88 95 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_34425 661db9456e13634e1a875237aa4df7e7 235 Gene3D G3DSA:3.40.1050.10 31 235 8.0E-66 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_34425 661db9456e13634e1a875237aa4df7e7 235 Pfam PF00484 Carbonic anhydrase 83 231 1.3E-36 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_34425 661db9456e13634e1a875237aa4df7e7 235 SMART SM00947 76 235 3.3E-48 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_21730 495d816415bbad0b112ce3fe32e90437 264 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 14 244 6.6E-72 T 12-10-2018 IPR012666 Cobalt transporter subunit CbtA, putative AFR_08890 853f94194950a5fae4f8d5c4288c0e1a 281 SUPERFAMILY SSF102705 11 275 1.44E-78 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily AFR_08890 853f94194950a5fae4f8d5c4288c0e1a 281 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 13 260 5.3E-69 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFR_08890 853f94194950a5fae4f8d5c4288c0e1a 281 Gene3D G3DSA:3.40.1390.30 108 239 3.9E-64 T 12-10-2018 AFR_08890 853f94194950a5fae4f8d5c4288c0e1a 281 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 11 272 4.5E-51 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFR_08890 853f94194950a5fae4f8d5c4288c0e1a 281 Gene3D G3DSA:3.40.1390.30 14 252 3.9E-64 T 12-10-2018 AFR_41045 fa510f55e9b792b6a84662bd0b0adcac 463 Pfam PF13365 Trypsin-like peptidase domain 280 439 2.0E-14 T 12-10-2018 AFR_41045 fa510f55e9b792b6a84662bd0b0adcac 463 Gene3D G3DSA:2.40.10.10 269 350 1.9E-6 T 12-10-2018 AFR_41045 fa510f55e9b792b6a84662bd0b0adcac 463 Gene3D G3DSA:2.40.10.10 351 452 2.8E-13 T 12-10-2018 AFR_41045 fa510f55e9b792b6a84662bd0b0adcac 463 PRINTS PR00839 V8 serine protease family signature 281 298 5.0E-6 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 AFR_41045 fa510f55e9b792b6a84662bd0b0adcac 463 PRINTS PR00839 V8 serine protease family signature 431 443 5.0E-6 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 AFR_41045 fa510f55e9b792b6a84662bd0b0adcac 463 PRINTS PR00839 V8 serine protease family signature 413 429 5.0E-6 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 AFR_41045 fa510f55e9b792b6a84662bd0b0adcac 463 SUPERFAMILY SSF50494 261 461 1.37E-24 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_01465 434f5634ce1744de992df01686f0d40f 548 SUPERFAMILY SSF54001 283 404 3.6E-28 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_01465 434f5634ce1744de992df01686f0d40f 548 PRINTS PR01217 Proline rich extensin signature 459 480 6.1E-12 T 12-10-2018 AFR_01465 434f5634ce1744de992df01686f0d40f 548 PRINTS PR01217 Proline rich extensin signature 484 500 6.1E-12 T 12-10-2018 AFR_01465 434f5634ce1744de992df01686f0d40f 548 PRINTS PR01217 Proline rich extensin signature 441 453 6.1E-12 T 12-10-2018 AFR_01465 434f5634ce1744de992df01686f0d40f 548 PRINTS PR01217 Proline rich extensin signature 420 436 6.1E-12 T 12-10-2018 AFR_01465 434f5634ce1744de992df01686f0d40f 548 Pfam PF00877 NlpC/P60 family 293 387 2.0E-16 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_01465 434f5634ce1744de992df01686f0d40f 548 Gene3D G3DSA:3.90.1720.10 194 400 5.8E-38 T 12-10-2018 AFR_36620 c131adae45fdf4bf2a166e25403c29a9 163 SUPERFAMILY SSF52799 21 159 3.96E-20 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFR_36620 c131adae45fdf4bf2a166e25403c29a9 163 Gene3D G3DSA:3.90.190.10 9 161 7.9E-22 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFR_20330 7fb403ffbe0a7ccc403026addc9fb83b 249 Gene3D G3DSA:2.40.440.10 92 249 1.1E-21 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_20330 7fb403ffbe0a7ccc403026addc9fb83b 249 Pfam PF03734 L,D-transpeptidase catalytic domain 126 247 2.9E-12 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_20330 7fb403ffbe0a7ccc403026addc9fb83b 249 SUPERFAMILY SSF141523 127 247 6.67E-20 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_26930 74de49b48330393cacf0375294ffe457 523 Gene3D G3DSA:3.30.420.40 250 509 8.1E-71 T 12-10-2018 AFR_26930 74de49b48330393cacf0375294ffe457 523 Gene3D G3DSA:3.30.420.40 1 248 7.4E-63 T 12-10-2018 AFR_26930 74de49b48330393cacf0375294ffe457 523 PIRSF PIRSF000538 1 500 3.7E-121 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_26930 74de49b48330393cacf0375294ffe457 523 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 247 5.6E-52 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFR_26930 74de49b48330393cacf0375294ffe457 523 SUPERFAMILY SSF53067 249 490 7.92E-55 T 12-10-2018 AFR_26930 74de49b48330393cacf0375294ffe457 523 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 366 386 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_26930 74de49b48330393cacf0375294ffe457 523 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 453 1.3E-37 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_26930 74de49b48330393cacf0375294ffe457 523 SUPERFAMILY SSF53067 1 247 6.57E-55 T 12-10-2018 AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 8.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 206 4.1E-5 T 12-10-2018 AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 8.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 Gene3D G3DSA:3.40.50.720 1 245 1.5E-71 T 12-10-2018 AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 SUPERFAMILY SSF51735 3 245 5.96E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_02700 e849dfd7dcaed0d52a744c287953c344 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 244 3.7E-55 T 12-10-2018 AFR_16215 a6cc4e612376646118cca9f6bdfc8b5f 363 Gene3D G3DSA:3.40.50.2300 141 341 7.4E-94 T 12-10-2018 AFR_16215 a6cc4e612376646118cca9f6bdfc8b5f 363 Pfam PF13407 Periplasmic binding protein domain 41 301 2.0E-53 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_16215 a6cc4e612376646118cca9f6bdfc8b5f 363 SUPERFAMILY SSF53822 37 337 1.57E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_16215 a6cc4e612376646118cca9f6bdfc8b5f 363 Gene3D G3DSA:3.40.50.2300 38 324 7.4E-94 T 12-10-2018 AFR_28605 a23e2bb76b21be883f059f4f3810d55a 353 Gene3D G3DSA:1.10.101.10 105 182 2.6E-7 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_28605 a23e2bb76b21be883f059f4f3810d55a 353 Pfam PF01471 Putative peptidoglycan binding domain 118 176 5.0E-8 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_28605 a23e2bb76b21be883f059f4f3810d55a 353 Pfam PF13437 HlyD family secretion protein 177 271 7.9E-6 T 12-10-2018 AFR_28605 a23e2bb76b21be883f059f4f3810d55a 353 SUPERFAMILY SSF47090 109 181 1.4E-9 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_36730 408d3b1bdaae521db13e9186a39c32e2 275 PIRSF PIRSF006648 22 259 7.5E-14 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_36730 408d3b1bdaae521db13e9186a39c32e2 275 Pfam PF12698 ABC-2 family transporter protein 56 246 1.4E-18 T 12-10-2018 AFR_38030 25ded5b7fa352e1005ec10ba39e9af20 134 SUPERFAMILY SSF109770 16 133 8.24E-51 T 12-10-2018 IPR036502 Nickel-containing superoxide dismutase superfamily MetaCyc: PWY-6854 AFR_38030 25ded5b7fa352e1005ec10ba39e9af20 134 Gene3D G3DSA:1.20.120.400 16 134 1.2E-46 T 12-10-2018 IPR036502 Nickel-containing superoxide dismutase superfamily MetaCyc: PWY-6854 AFR_38030 25ded5b7fa352e1005ec10ba39e9af20 134 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 9 133 1.1E-46 T 12-10-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 AFR_38030 25ded5b7fa352e1005ec10ba39e9af20 134 Pfam PF09055 Nickel-containing superoxide dismutase 12 132 4.0E-45 T 12-10-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 AFR_32895 ab874663222874ff67cda7c44bf6796d 235 Gene3D G3DSA:3.40.50.720 1 234 1.1E-69 T 12-10-2018 AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 174 0.002 T 12-10-2018 AFR_32895 ab874663222874ff67cda7c44bf6796d 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 234 3.4E-53 T 12-10-2018 AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 9.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 9.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 9.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 9.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 9.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32895 ab874663222874ff67cda7c44bf6796d 235 SUPERFAMILY SSF51735 2 234 4.79E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_32590 6eed1df1def040c7e1137118abb985f4 452 Pfam PF00652 Ricin-type beta-trefoil lectin domain 328 448 5.4E-23 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_32590 6eed1df1def040c7e1137118abb985f4 452 SUPERFAMILY SSF49899 38 311 1.37E-56 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_32590 6eed1df1def040c7e1137118abb985f4 452 SUPERFAMILY SSF50370 318 448 4.73E-33 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_32590 6eed1df1def040c7e1137118abb985f4 452 Gene3D G3DSA:2.80.10.50 322 451 1.9E-34 T 12-10-2018 AFR_32590 6eed1df1def040c7e1137118abb985f4 452 SMART SM00458 323 451 3.2E-18 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_32590 6eed1df1def040c7e1137118abb985f4 452 Gene3D G3DSA:2.60.120.200 37 314 4.4E-68 T 12-10-2018 AFR_32590 6eed1df1def040c7e1137118abb985f4 452 Pfam PF00722 Glycosyl hydrolases family 16 101 308 2.4E-24 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AFR_20335 3a341c164e4a42d6e4adade8c773d602 257 SUPERFAMILY SSF53335 2 229 1.4E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_20335 3a341c164e4a42d6e4adade8c773d602 257 Gene3D G3DSA:3.40.50.150 43 224 1.4E-24 T 12-10-2018 AFR_20335 3a341c164e4a42d6e4adade8c773d602 257 Gene3D G3DSA:2.20.25.570 146 206 1.4E-24 T 12-10-2018 AFR_20335 3a341c164e4a42d6e4adade8c773d602 257 Pfam PF13489 Methyltransferase domain 41 173 5.5E-10 T 12-10-2018 AFR_10330 283457749d786d75db1f20bff2650711 289 Pfam PF08445 FR47-like protein 218 277 2.4E-9 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_10330 283457749d786d75db1f20bff2650711 289 SUPERFAMILY SSF55729 179 280 1.95E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_10330 283457749d786d75db1f20bff2650711 289 Gene3D G3DSA:3.40.630.30 4 286 4.9E-36 T 12-10-2018 AFR_00490 deb885418c26b5f8bc49ebeb7dcf8d3e 391 SUPERFAMILY SSF52518 50 387 2.53E-91 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_00490 deb885418c26b5f8bc49ebeb7dcf8d3e 391 Gene3D G3DSA:3.40.50.970 17 379 2.4E-106 T 12-10-2018 AFR_00490 deb885418c26b5f8bc49ebeb7dcf8d3e 391 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 31 378 4.3E-127 T 12-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AFR_00490 deb885418c26b5f8bc49ebeb7dcf8d3e 391 Pfam PF00676 Dehydrogenase E1 component 68 339 1.0E-66 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFR_07415 4f0befb0f6afce771ff1942a565a29db 141 Gene3D G3DSA:1.10.490.10 7 134 9.7E-49 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFR_07415 4f0befb0f6afce771ff1942a565a29db 141 Pfam PF01152 Bacterial-like globin 11 125 3.2E-32 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 AFR_07415 4f0befb0f6afce771ff1942a565a29db 141 SUPERFAMILY SSF46458 11 130 2.04E-37 T 12-10-2018 IPR009050 Globin-like superfamily AFR_01575 7c954ae7ea063674843e9ab21a759706 283 Gene3D G3DSA:3.40.190.10 82 182 9.8E-91 T 12-10-2018 AFR_01575 7c954ae7ea063674843e9ab21a759706 283 Pfam PF02621 Menaquinone biosynthesis 9 265 7.5E-75 T 12-10-2018 IPR003773 Menaquinone biosynthesis enzyme AFR_01575 7c954ae7ea063674843e9ab21a759706 283 Hamap MF_00995 Chorismate dehydratase [mqnA]. 9 270 31.62 T 12-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFR_01575 7c954ae7ea063674843e9ab21a759706 283 Gene3D G3DSA:3.40.190.10 9 260 9.8E-91 T 12-10-2018 AFR_01575 7c954ae7ea063674843e9ab21a759706 283 SUPERFAMILY SSF53850 8 271 3.62E-80 T 12-10-2018 AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 Pfam PF00580 UvrD/REP helicase N-terminal domain 30 315 8.6E-38 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 Gene3D G3DSA:3.40.50.300 581 679 6.4E-6 T 12-10-2018 AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 Pfam PF13361 UvrD-like helicase C-terminal domain 831 932 2.1E-20 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 SUPERFAMILY SSF52540 575 954 2.25E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 SUPERFAMILY SSF52540 29 349 2.17E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 Gene3D G3DSA:3.40.50.300 785 958 1.2E-27 T 12-10-2018 AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1222 1462 6.6E-37 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 Gene3D G3DSA:1.10.10.160 128 233 2.0E-58 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFR_38480 31b9db5254bfca46cf007e2c57ca8cf0 1473 Gene3D G3DSA:3.40.50.300 30 316 2.0E-58 T 12-10-2018 AFR_42595 f8427a588f17229a328278e540b7872f 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 264 2.8E-42 T 12-10-2018 AFR_42595 f8427a588f17229a328278e540b7872f 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 231 5.6E-19 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFR_42595 f8427a588f17229a328278e540b7872f 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 9 264 4.9E-44 T 12-10-2018 IPR000150 Cof family GO:0016787 AFR_42595 f8427a588f17229a328278e540b7872f 270 SUPERFAMILY SSF56784 7 268 8.4E-51 T 12-10-2018 IPR036412 HAD-like superfamily AFR_42595 f8427a588f17229a328278e540b7872f 270 Gene3D G3DSA:3.40.50.1000 8 264 4.3E-51 T 12-10-2018 IPR023214 HAD superfamily AFR_42595 f8427a588f17229a328278e540b7872f 270 Gene3D G3DSA:3.30.1240.10 88 192 4.3E-51 T 12-10-2018 AFR_00890 50107d635872a5e10cd4399143708c72 387 Pfam PF00348 Polyprenyl synthetase 57 309 4.1E-50 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFR_00890 50107d635872a5e10cd4399143708c72 387 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 107 121 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFR_00890 50107d635872a5e10cd4399143708c72 387 Gene3D G3DSA:1.10.600.10 16 386 1.0E-104 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_00890 50107d635872a5e10cd4399143708c72 387 SUPERFAMILY SSF48576 33 385 1.51E-69 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_00890 50107d635872a5e10cd4399143708c72 387 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 256 268 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFR_39845 9686209436ed26b86a70cb3162a4c19b 289 PRINTS PR01217 Proline rich extensin signature 251 276 3.7E-9 T 12-10-2018 AFR_39845 9686209436ed26b86a70cb3162a4c19b 289 PRINTS PR01217 Proline rich extensin signature 127 139 3.7E-9 T 12-10-2018 AFR_39845 9686209436ed26b86a70cb3162a4c19b 289 PRINTS PR01217 Proline rich extensin signature 77 89 3.7E-9 T 12-10-2018 AFR_39845 9686209436ed26b86a70cb3162a4c19b 289 PRINTS PR01217 Proline rich extensin signature 162 178 3.7E-9 T 12-10-2018 AFR_39845 9686209436ed26b86a70cb3162a4c19b 289 PRINTS PR01217 Proline rich extensin signature 139 160 3.7E-9 T 12-10-2018 AFR_12620 2b40661f07464bfe0f884c1831705887 128 ProSitePatterns PS01117 MarR-type HTH domain signature. 46 80 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_12620 2b40661f07464bfe0f884c1831705887 128 Pfam PF12802 MarR family 12 70 7.9E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12620 2b40661f07464bfe0f884c1831705887 128 SMART SM00347 7 107 3.3E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12620 2b40661f07464bfe0f884c1831705887 128 Gene3D G3DSA:1.10.10.10 1 120 1.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12620 2b40661f07464bfe0f884c1831705887 128 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 63 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12620 2b40661f07464bfe0f884c1831705887 128 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12620 2b40661f07464bfe0f884c1831705887 128 PRINTS PR00598 Bacterial regulatory protein MarR family signature 31 47 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12620 2b40661f07464bfe0f884c1831705887 128 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 117 3.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12620 2b40661f07464bfe0f884c1831705887 128 SUPERFAMILY SSF46785 6 119 6.62E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_12030 9bb555be8ec60abacdcbffdf2248ef9e 205 Gene3D G3DSA:1.20.1510.10 19 201 1.1E-16 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_12030 9bb555be8ec60abacdcbffdf2248ef9e 205 Pfam PF01545 Cation efflux family 27 195 2.8E-11 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_12030 9bb555be8ec60abacdcbffdf2248ef9e 205 SUPERFAMILY SSF161111 17 200 1.96E-28 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_17095 fafa8f237bf184f0521aa15e105a87ed 422 SUPERFAMILY SSF103473 8 401 7.06E-36 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_17095 fafa8f237bf184f0521aa15e105a87ed 422 Pfam PF05977 Transmembrane secretion effector 2 396 3.4E-40 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_17095 fafa8f237bf184f0521aa15e105a87ed 422 Gene3D G3DSA:1.20.1250.20 3 400 1.6E-31 T 12-10-2018 AFR_05885 487521b79036480bf4a7c5c7d1908e0d 229 SUPERFAMILY SSF53955 156 220 2.14E-9 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_01345 1accad778959285d9386a0a5da670be9 324 Pfam PF01578 Cytochrome C assembly protein 105 316 2.5E-42 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFR_01345 1accad778959285d9386a0a5da670be9 324 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 83 319 1.6E-65 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 Gene3D G3DSA:1.20.1250.20 280 481 1.0E-17 T 12-10-2018 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 SUPERFAMILY SSF103473 13 478 1.27E-66 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_16935 d051b7c4198781a3956dce407766a3f1 494 Gene3D G3DSA:1.20.1720.10 23 212 1.6E-48 T 12-10-2018 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 Pfam PF07690 Major Facilitator Superfamily 27 421 8.5E-54 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.0E-5 T 12-10-2018 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 86 108 1.0E-5 T 12-10-2018 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 1.0E-5 T 12-10-2018 AFR_16935 d051b7c4198781a3956dce407766a3f1 494 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 428 2.6E-80 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_39275 10232c2fb9b793a530366d1bf1e4fd54 375 SUPERFAMILY SSF51905 7 333 6.92E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_39275 10232c2fb9b793a530366d1bf1e4fd54 375 Pfam PF01494 FAD binding domain 7 161 1.0E-15 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_39275 10232c2fb9b793a530366d1bf1e4fd54 375 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 7 289 1.9E-57 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AFR_39275 10232c2fb9b793a530366d1bf1e4fd54 375 Gene3D G3DSA:3.50.50.60 4 330 2.2E-65 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_39275 10232c2fb9b793a530366d1bf1e4fd54 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 139 154 9.4E-17 T 12-10-2018 AFR_39275 10232c2fb9b793a530366d1bf1e4fd54 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 9.4E-17 T 12-10-2018 AFR_39275 10232c2fb9b793a530366d1bf1e4fd54 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 255 270 9.4E-17 T 12-10-2018 AFR_20935 65d5cb0f01280886a60b1d343b1ebb56 379 SUPERFAMILY SSF53850 61 345 3.01E-42 T 12-10-2018 AFR_20935 65d5cb0f01280886a60b1d343b1ebb56 379 Gene3D G3DSA:3.40.190.10 79 336 2.5E-33 T 12-10-2018 AFR_20935 65d5cb0f01280886a60b1d343b1ebb56 379 Gene3D G3DSA:3.40.190.10 167 286 2.5E-33 T 12-10-2018 AFR_20935 65d5cb0f01280886a60b1d343b1ebb56 379 Pfam PF13343 Bacterial extracellular solute-binding protein 135 334 1.6E-27 T 12-10-2018 AFR_28700 f65067a1be681b24cc90a6536caea166 125 Pfam PF13581 Histidine kinase-like ATPase domain 8 74 2.6E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28700 f65067a1be681b24cc90a6536caea166 125 Gene3D G3DSA:3.30.565.10 1 81 6.7E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28700 f65067a1be681b24cc90a6536caea166 125 SUPERFAMILY SSF55874 3 75 2.85E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17175 400b4ba522ebbea50dcffe1927af6c7c 331 SUPERFAMILY SSF51182 17 329 1.03E-43 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_17175 400b4ba522ebbea50dcffe1927af6c7c 331 Gene3D G3DSA:2.60.120.10 16 232 3.4E-40 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_09850 fb56d15bcada42e658fcfa962a369332 162 SUPERFAMILY SSF55826 21 161 1.57E-35 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_09850 fb56d15bcada42e658fcfa962a369332 162 Gene3D G3DSA:3.90.960.10 3 162 4.4E-42 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_09850 fb56d15bcada42e658fcfa962a369332 162 Pfam PF04073 Aminoacyl-tRNA editing domain 34 152 9.2E-30 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFR_18375 860318a83cbcdc563c3dd14ed088acd7 556 SUPERFAMILY SSF90123 12 319 6.41E-44 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_18375 860318a83cbcdc563c3dd14ed088acd7 556 Gene3D G3DSA:3.40.50.300 363 555 4.2E-43 T 12-10-2018 AFR_18375 860318a83cbcdc563c3dd14ed088acd7 556 Pfam PF00664 ABC transporter transmembrane region 27 294 5.2E-20 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_18375 860318a83cbcdc563c3dd14ed088acd7 556 Gene3D G3DSA:1.20.1560.10 4 323 5.6E-43 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_18375 860318a83cbcdc563c3dd14ed088acd7 556 ProSitePatterns PS00211 ABC transporters family signature. 458 472 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_18375 860318a83cbcdc563c3dd14ed088acd7 556 Pfam PF00005 ABC transporter 380 486 4.8E-9 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18375 860318a83cbcdc563c3dd14ed088acd7 556 SUPERFAMILY SSF52540 378 552 6.96E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41890 41cb091b932dbdb0a12fa7a915a9e00e 174 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 171 8.9E-44 T 12-10-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative AFR_08320 e0441d2dd46c8d962f599f2bb3a182ab 183 SUPERFAMILY SSF55729 20 159 9.09E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_08320 e0441d2dd46c8d962f599f2bb3a182ab 183 Pfam PF13420 Acetyltransferase (GNAT) domain 73 173 1.7E-11 T 12-10-2018 AFR_08320 e0441d2dd46c8d962f599f2bb3a182ab 183 Gene3D G3DSA:3.40.630.30 19 180 5.3E-37 T 12-10-2018 AFR_42385 f1d0041d81aa863015fe2ff1d188e6b0 352 Gene3D G3DSA:1.20.58.340 275 352 3.1E-20 T 12-10-2018 AFR_42385 f1d0041d81aa863015fe2ff1d188e6b0 352 SUPERFAMILY SSF144083 287 349 6.8E-16 T 12-10-2018 AFR_42385 f1d0041d81aa863015fe2ff1d188e6b0 352 Pfam PF01544 CorA-like Mg2+ transporter protein 54 348 2.1E-57 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFR_42385 f1d0041d81aa863015fe2ff1d188e6b0 352 Gene3D G3DSA:3.30.460.20 12 160 3.0E-27 T 12-10-2018 AFR_42385 f1d0041d81aa863015fe2ff1d188e6b0 352 Gene3D G3DSA:1.20.58.340 161 274 5.7E-33 T 12-10-2018 AFR_42385 f1d0041d81aa863015fe2ff1d188e6b0 352 SUPERFAMILY SSF143865 21 284 1.57E-64 T 12-10-2018 AFR_30850 c366151bee7e3b67a2d370b96ef9f927 155 Pfam PF01814 Hemerythrin HHE cation binding domain 17 139 1.2E-14 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFR_30850 c366151bee7e3b67a2d370b96ef9f927 155 Gene3D G3DSA:1.20.120.520 3 147 4.1E-18 T 12-10-2018 AFR_33910 0e24c7dd83cf0fee41ca619e4600997d 396 Gene3D G3DSA:2.60.110.10 41 375 1.1E-106 T 12-10-2018 IPR037176 Osmotin/thaumatin-like superfamily AFR_33910 0e24c7dd83cf0fee41ca619e4600997d 396 Pfam PF16483 Beta-1,3-glucanase 37 392 1.4E-97 T 12-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 AFR_33910 0e24c7dd83cf0fee41ca619e4600997d 396 Gene3D G3DSA:3.30.920.50 235 349 1.1E-106 T 12-10-2018 AFR_29495 11646c822934ee4149ddef008d430704 120 SUPERFAMILY SSF54593 13 118 1.75E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_29495 11646c822934ee4149ddef008d430704 120 Gene3D G3DSA:3.10.180.10 6 118 6.1E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_41595 f00e8a0f36d0914f54288cdcf64a8639 237 SUPERFAMILY SSF52833 102 215 3.79E-21 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_41595 f00e8a0f36d0914f54288cdcf64a8639 237 Gene3D G3DSA:3.40.30.10 92 229 1.0E-21 T 12-10-2018 AFR_41595 f00e8a0f36d0914f54288cdcf64a8639 237 Pfam PF00578 AhpC/TSA family 102 208 7.2E-12 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_14680 07a464f90c9dcab01d5eeadcfb08fb51 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14680 07a464f90c9dcab01d5eeadcfb08fb51 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14680 07a464f90c9dcab01d5eeadcfb08fb51 207 Gene3D G3DSA:1.10.357.10 1 190 3.5E-42 T 12-10-2018 AFR_14680 07a464f90c9dcab01d5eeadcfb08fb51 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 8.2E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14680 07a464f90c9dcab01d5eeadcfb08fb51 207 SUPERFAMILY SSF48498 80 185 4.45E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_14680 07a464f90c9dcab01d5eeadcfb08fb51 207 SUPERFAMILY SSF46689 6 76 6.48E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_25600 2a335c5c0f3367fc42af259fd5d3d5f6 293 Pfam PF00892 EamA-like transporter family 147 276 1.2E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_25600 2a335c5c0f3367fc42af259fd5d3d5f6 293 SUPERFAMILY SSF103481 185 281 1.01E-7 T 12-10-2018 AFR_25600 2a335c5c0f3367fc42af259fd5d3d5f6 293 SUPERFAMILY SSF103481 46 138 1.44E-6 T 12-10-2018 AFR_14800 b63322a5ed431889e2fcaa9017629a57 185 Gene3D G3DSA:3.30.450.40 23 130 4.3E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 22 383 2.0E-94 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 PRINTS PR00447 Natural resistance-associated macrophage protein signature 334 351 1.6E-35 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 PRINTS PR00447 Natural resistance-associated macrophage protein signature 306 325 1.6E-35 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 PRINTS PR00447 Natural resistance-associated macrophage protein signature 128 147 1.6E-35 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 PRINTS PR00447 Natural resistance-associated macrophage protein signature 202 225 1.6E-35 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 PRINTS PR00447 Natural resistance-associated macrophage protein signature 100 126 1.6E-35 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 PRINTS PR00447 Natural resistance-associated macrophage protein signature 153 174 1.6E-35 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 5 416 34.539 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_22015 0c50313e960c4397ef7c8e727be5cfee 418 Pfam PF01566 Natural resistance-associated macrophage protein 41 390 9.4E-117 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFR_39695 aa7e2cafa79340770b00a7845da1463d 303 Gene3D G3DSA:3.40.50.620 10 213 1.2E-54 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_39695 aa7e2cafa79340770b00a7845da1463d 303 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 12 303 5.1E-134 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFR_39695 aa7e2cafa79340770b00a7845da1463d 303 SUPERFAMILY SSF52402 9 210 7.22E-62 T 12-10-2018 AFR_39695 aa7e2cafa79340770b00a7845da1463d 303 PIRSF PIRSF002936 3 303 3.5E-137 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFR_39695 aa7e2cafa79340770b00a7845da1463d 303 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 33 256 4.7E-45 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFR_28850 719d84c382bc71af9e906259b6929769 154 SUPERFAMILY SSF46785 9 150 1.23E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_28850 719d84c382bc71af9e906259b6929769 154 SMART SM00347 32 135 8.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_28850 719d84c382bc71af9e906259b6929769 154 Pfam PF01047 MarR family 41 98 4.9E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_28850 719d84c382bc71af9e906259b6929769 154 Gene3D G3DSA:1.10.10.10 8 153 2.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 9.5E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 Gene3D G3DSA:3.30.70.920 59 141 3.0E-20 T 12-10-2018 AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 SUPERFAMILY SSF46785 4 64 5.85E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 Gene3D G3DSA:1.10.10.10 1 58 4.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 SUPERFAMILY SSF54909 66 153 4.29E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 SMART SM00344 5 114 9.9E-27 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_06835 c4e2a77c1486a0c94a27f9ce7ff56e3d 155 Pfam PF01037 Lrp/AsnC ligand binding domain 72 144 5.8E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 SMART SM00421 730 787 2.5E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 Gene3D G3DSA:1.10.10.10 741 791 7.5E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 PRINTS PR00364 Disease resistance protein signature 217 231 1.2E-6 T 12-10-2018 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 PRINTS PR00364 Disease resistance protein signature 40 55 1.2E-6 T 12-10-2018 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 PRINTS PR00364 Disease resistance protein signature 109 123 1.2E-6 T 12-10-2018 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 SUPERFAMILY SSF52540 14 280 5.53E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 747 763 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 763 775 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 733 747 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 Pfam PF00196 Bacterial regulatory proteins, luxR family 733 784 1.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 SUPERFAMILY SSF48452 451 619 4.74E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 Gene3D G3DSA:3.40.50.300 8 159 5.7E-19 T 12-10-2018 AFR_32950 8dcf3992a7579e32802cd942eaeee687 793 SUPERFAMILY SSF46894 723 787 2.82E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 SUPERFAMILY SSF111369 188 273 1.83E-6 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Pfam PF13533 Biotin-lipoyl like 58 103 1.4E-7 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Gene3D G3DSA:2.40.420.20 326 381 9.9E-6 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Gene3D G3DSA:2.40.420.20 32 41 1.8E-10 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Pfam PF13437 HlyD family secretion protein 211 312 4.1E-11 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Gene3D G3DSA:2.40.50.100 56 89 1.8E-10 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 SUPERFAMILY SSF111369 43 113 7.32E-7 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Gene3D G3DSA:2.40.30.170 226 325 2.9E-17 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Gene3D G3DSA:1.10.287.470 90 114 1.8E-10 T 12-10-2018 AFR_20560 093955f8b146c5390fd72e55d7f2cb54 382 Gene3D G3DSA:2.40.30.170 42 55 1.8E-10 T 12-10-2018 AFR_29100 a8488a193702aa3ec9570ce0a262f032 117 SUPERFAMILY SSF54909 11 116 6.43E-29 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_29100 a8488a193702aa3ec9570ce0a262f032 117 Pfam PF05336 L-rhamnose mutarotase 12 116 4.1E-29 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 AFR_29100 a8488a193702aa3ec9570ce0a262f032 117 Gene3D G3DSA:3.30.70.100 11 104 2.3E-23 T 12-10-2018 AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 359 381 280.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 444 466 62.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 537 560 4600.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 202 224 5200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 489 511 12.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 335 357 1400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 468 488 140.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 311 333 560.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 398 420 740.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SMART SM00710 421 442 810.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_22715 56bd5a9b67107402514ba82159ff8486 617 SUPERFAMILY SSF51126 106 527 5.9E-21 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_22715 56bd5a9b67107402514ba82159ff8486 617 Gene3D G3DSA:2.160.20.10 439 552 3.5E-15 T 12-10-2018 IPR012334 Pectin lyase fold AFR_22715 56bd5a9b67107402514ba82159ff8486 617 Pfam PF13229 Right handed beta helix region 291 381 6.7E-7 T 12-10-2018 IPR039448 Right handed beta helix domain AFR_22715 56bd5a9b67107402514ba82159ff8486 617 Pfam PF05048 Periplasmic copper-binding protein (NosD) 397 522 2.4E-11 T 12-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFR_19040 2ccf532945226930d66acf1d63ab2f42 323 SMART SM01092 224 322 4.2E-27 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_19040 2ccf532945226930d66acf1d63ab2f42 323 Gene3D G3DSA:3.30.390.50 221 323 5.1E-26 T 12-10-2018 AFR_19040 2ccf532945226930d66acf1d63ab2f42 323 SUPERFAMILY SSF55447 223 321 1.44E-26 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily AFR_19040 2ccf532945226930d66acf1d63ab2f42 323 Gene3D G3DSA:3.30.465.10 1 219 5.2E-79 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFR_19040 2ccf532945226930d66acf1d63ab2f42 323 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 224 317 4.4E-18 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFR_19040 2ccf532945226930d66acf1d63ab2f42 323 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 217 1.4E-45 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFR_19040 2ccf532945226930d66acf1d63ab2f42 323 SUPERFAMILY SSF56176 1 217 1.74E-58 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 Pfam PF00072 Response regulator receiver domain 4 117 9.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 SUPERFAMILY SSF52172 2 129 6.83E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 SMART SM00421 152 209 5.0E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 SUPERFAMILY SSF46894 142 215 2.65E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 Gene3D G3DSA:3.40.50.12740 2 215 6.6E-66 T 12-10-2018 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 SMART SM00448 2 117 1.4E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21695 fb86cc1fbdd46385c9fe71591f94ba69 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.9E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_04930 e5126fc457f367d3b85c0ee8101e42ca 522 Pfam PF00174 Oxidoreductase molybdopterin binding domain 251 394 5.3E-36 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFR_04930 e5126fc457f367d3b85c0ee8101e42ca 522 Gene3D G3DSA:2.60.40.650 414 522 2.1E-26 T 12-10-2018 AFR_04930 e5126fc457f367d3b85c0ee8101e42ca 522 Gene3D G3DSA:3.90.420.10 201 413 1.1E-44 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_04930 e5126fc457f367d3b85c0ee8101e42ca 522 SUPERFAMILY SSF56524 233 419 6.54E-54 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AFR_04930 e5126fc457f367d3b85c0ee8101e42ca 522 SUPERFAMILY SSF81296 412 521 4.67E-26 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_18070 5e59a82b08781d67addb66214c258e4a 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 3.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_18070 5e59a82b08781d67addb66214c258e4a 192 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 191 8.1E-19 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_18070 5e59a82b08781d67addb66214c258e4a 192 SUPERFAMILY SSF46689 1 75 3.18E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_18070 5e59a82b08781d67addb66214c258e4a 192 SUPERFAMILY SSF48498 83 191 1.72E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_18070 5e59a82b08781d67addb66214c258e4a 192 Gene3D G3DSA:1.10.357.10 1 190 9.3E-47 T 12-10-2018 AFR_25265 df586616e3abf8cd00fe96e94f3160f1 467 Gene3D G3DSA:1.10.2020.10 45 145 6.9E-128 T 12-10-2018 AFR_25265 df586616e3abf8cd00fe96e94f3160f1 467 Gene3D G3DSA:3.20.20.140 13 454 6.9E-128 T 12-10-2018 AFR_25265 df586616e3abf8cd00fe96e94f3160f1 467 Pfam PF02614 Glucuronate isomerase 13 465 6.9E-71 T 12-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 AFR_25265 df586616e3abf8cd00fe96e94f3160f1 467 Hamap MF_00675 Uronate isomerase [uxaC]. 1 467 38.152 T 12-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 AFR_25265 df586616e3abf8cd00fe96e94f3160f1 467 SUPERFAMILY SSF51556 13 466 5.71E-148 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_22985 d622179320e1266609335a0a024b999f 347 Pfam PF01636 Phosphotransferase enzyme family 66 284 8.4E-20 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_22985 d622179320e1266609335a0a024b999f 347 Gene3D G3DSA:3.90.1200.10 136 309 1.0E-19 T 12-10-2018 AFR_22985 d622179320e1266609335a0a024b999f 347 SUPERFAMILY SSF56112 40 305 4.33E-40 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_21140 a976a1605a733d704b63f041abc93a40 170 SUPERFAMILY SSF47413 2 57 4.44E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_21140 a976a1605a733d704b63f041abc93a40 170 Pfam PF01381 Helix-turn-helix 2 50 1.7E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_21140 a976a1605a733d704b63f041abc93a40 170 Pfam PF07883 Cupin domain 101 155 2.3E-9 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_21140 a976a1605a733d704b63f041abc93a40 170 Gene3D G3DSA:1.10.260.40 1 53 2.9E-13 T 12-10-2018 AFR_21140 a976a1605a733d704b63f041abc93a40 170 SMART SM00530 1 50 5.1E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_21140 a976a1605a733d704b63f041abc93a40 170 Gene3D G3DSA:2.60.120.10 54 168 7.2E-13 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_21140 a976a1605a733d704b63f041abc93a40 170 SUPERFAMILY SSF51182 54 155 1.54E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_37040 f8859fe30bd884a47b906ce99e8a2485 100 Pfam PF02656 Domain of unknown function (DUF202) 4 66 6.1E-8 T 12-10-2018 IPR003807 Domain of unknown function DUF202 AFR_37380 f020d52d07abda66863571abafed6208 443 Gene3D G3DSA:3.40.640.10 55 305 5.0E-172 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_37380 f020d52d07abda66863571abafed6208 443 SUPERFAMILY SSF53383 26 436 3.44E-168 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_37380 f020d52d07abda66863571abafed6208 443 PIRSF PIRSF000412 9 440 1.3E-166 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_37380 f020d52d07abda66863571abafed6208 443 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 25 437 50.503 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_37380 f020d52d07abda66863571abafed6208 443 Gene3D G3DSA:3.90.1150.10 30 407 5.0E-172 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_37380 f020d52d07abda66863571abafed6208 443 Pfam PF00464 Serine hydroxymethyltransferase 26 402 9.9E-161 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFR_01755 b1b295851bbad53c52b9ab16f7c6580e 150 Pfam PF00583 Acetyltransferase (GNAT) family 52 128 6.7E-10 T 12-10-2018 IPR000182 GNAT domain AFR_01755 b1b295851bbad53c52b9ab16f7c6580e 150 Gene3D G3DSA:3.40.630.30 7 138 2.8E-33 T 12-10-2018 AFR_01755 b1b295851bbad53c52b9ab16f7c6580e 150 SUPERFAMILY SSF55729 20 141 5.15E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_34375 a740c535c14770c543f16713ce386aef 377 Gene3D G3DSA:3.50.50.60 2 361 1.4E-96 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_34375 a740c535c14770c543f16713ce386aef 377 Pfam PF01494 FAD binding domain 3 164 2.4E-7 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_34375 a740c535c14770c543f16713ce386aef 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 8.4E-13 T 12-10-2018 AFR_34375 a740c535c14770c543f16713ce386aef 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 8.4E-13 T 12-10-2018 AFR_34375 a740c535c14770c543f16713ce386aef 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 8.4E-13 T 12-10-2018 AFR_34375 a740c535c14770c543f16713ce386aef 377 SUPERFAMILY SSF51905 3 357 1.11E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23305 5af8353128e8ce81b2aae451d0d9c329 274 SUPERFAMILY SSF53448 31 247 4.05E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23305 5af8353128e8ce81b2aae451d0d9c329 274 Gene3D G3DSA:3.90.550.10 42 222 5.7E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23305 5af8353128e8ce81b2aae451d0d9c329 274 Pfam PF13641 Glycosyltransferase like family 2 75 216 4.2E-7 T 12-10-2018 AFR_24110 a773cde843d546e62a2fb4451ed52478 157 SUPERFAMILY SSF55826 8 149 2.49E-32 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_24110 a773cde843d546e62a2fb4451ed52478 157 Pfam PF04073 Aminoacyl-tRNA editing domain 21 135 1.7E-26 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFR_24110 a773cde843d546e62a2fb4451ed52478 157 Gene3D G3DSA:3.90.960.10 2 151 9.6E-37 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFR_13690 473db5507395d9721372c6316c909752 97 SUPERFAMILY SSF52091 2 79 8.63E-13 T 12-10-2018 IPR036513 STAS domain superfamily AFR_13690 473db5507395d9721372c6316c909752 97 Gene3D G3DSA:3.30.750.24 1 84 5.2E-20 T 12-10-2018 IPR036513 STAS domain superfamily AFR_13690 473db5507395d9721372c6316c909752 97 Pfam PF13466 STAS domain 4 78 5.1E-12 T 12-10-2018 IPR002645 STAS domain AFR_42690 66e328d0f97972bb50add9e3dd542858 171 Pfam PF01478 Type IV leader peptidase family 31 127 1.7E-8 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFR_04875 f87d27ccf93905302e08421f2ce97fff 561 SUPERFAMILY SSF52540 385 557 1.99E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04875 f87d27ccf93905302e08421f2ce97fff 561 Gene3D G3DSA:3.40.50.300 361 560 2.0E-42 T 12-10-2018 AFR_04875 f87d27ccf93905302e08421f2ce97fff 561 Pfam PF00005 ABC transporter 388 491 4.6E-8 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04875 f87d27ccf93905302e08421f2ce97fff 561 ProSitePatterns PS00211 ABC transporters family signature. 463 477 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_04875 f87d27ccf93905302e08421f2ce97fff 561 Pfam PF00664 ABC transporter transmembrane region 35 302 2.1E-24 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_04875 f87d27ccf93905302e08421f2ce97fff 561 Gene3D G3DSA:1.20.1560.10 7 335 1.4E-50 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_04875 f87d27ccf93905302e08421f2ce97fff 561 SUPERFAMILY SSF90123 19 335 5.23E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_28895 0ca8242d9e0edf1b3dc52cf4c38d3e36 148 SUPERFAMILY SSF46785 6 136 1.67E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_28895 0ca8242d9e0edf1b3dc52cf4c38d3e36 148 Gene3D G3DSA:1.10.10.10 2 137 3.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28895 0ca8242d9e0edf1b3dc52cf4c38d3e36 148 SMART SM00347 25 123 1.5E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_28895 0ca8242d9e0edf1b3dc52cf4c38d3e36 148 Pfam PF12802 MarR family 30 87 8.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 27 281 1.4E-60 T 12-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 711 761 2.7E-14 T 12-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 Gene3D G3DSA:1.50.10.10 332 693 6.2E-119 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 SUPERFAMILY SSF74650 16 282 1.95E-64 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 Gene3D G3DSA:2.70.98.40 15 283 1.0E-58 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 338 702 3.3E-131 T 12-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 PIRSF PIRSF036289 11 773 1.3E-211 T 12-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 Gene3D G3DSA:2.60.420.10 694 761 5.1E-18 T 12-10-2018 AFR_12845 c2a54bcd60618ffc6b1a850cc5c1f97c 798 SUPERFAMILY SSF48208 291 759 7.06E-114 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_27340 45cfe7f79440cbebd28480ae08ea17af 296 Pfam PF01636 Phosphotransferase enzyme family 38 254 1.3E-22 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_27340 45cfe7f79440cbebd28480ae08ea17af 296 SUPERFAMILY SSF56112 18 265 6.41E-35 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_27340 45cfe7f79440cbebd28480ae08ea17af 296 Gene3D G3DSA:3.90.1200.10 110 265 6.1E-14 T 12-10-2018 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 49 2.0E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 Gene3D G3DSA:1.10.260.40 1 59 2.0E-21 T 12-10-2018 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 SMART SM00354 1 72 1.8E-26 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 Pfam PF13377 Periplasmic binding protein-like domain 176 334 9.8E-33 T 12-10-2018 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 SUPERFAMILY SSF53822 62 337 1.12E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 Gene3D G3DSA:3.40.50.2300 167 296 5.2E-68 T 12-10-2018 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 Gene3D G3DSA:3.40.50.2300 63 311 5.2E-68 T 12-10-2018 AFR_18280 e763fdde0eb64476f41721b8e50f1483 340 SUPERFAMILY SSF47413 3 56 1.01E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 SMART SM00382 390 576 8.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 ProSitePatterns PS00211 ABC transporters family signature. 502 516 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 SUPERFAMILY SSF52540 355 597 1.47E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 SUPERFAMILY SSF90123 26 350 4.05E-67 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 Gene3D G3DSA:3.40.50.300 352 598 5.0E-91 T 12-10-2018 AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 Pfam PF00005 ABC transporter 383 530 6.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 Gene3D G3DSA:1.20.1560.10 8 350 7.7E-77 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_27660 4130aec05c2392ac6fff6063e9719db8 598 Pfam PF00664 ABC transporter transmembrane region 45 317 9.7E-40 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_18810 baf330925b01dbd24f865b96f48b52dc 264 Pfam PF00950 ABC 3 transport family 1 252 7.6E-51 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFR_18810 baf330925b01dbd24f865b96f48b52dc 264 SUPERFAMILY SSF81345 3 250 6.93E-29 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_00865 fb55f41a1b96b75b13532338dce956e3 127 Gene3D G3DSA:2.60.40.1240 4 121 7.1E-5 T 12-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 SUPERFAMILY SSF51658 4 392 1.44E-111 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 3 392 1.4E-214 T 12-10-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 Hamap MF_00455 Xylose isomerase [xylA]. 1 391 36.731 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 Pfam PF01261 Xylose isomerase-like TIM barrel 42 265 4.2E-27 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 Gene3D G3DSA:3.20.20.150 2 395 3.9E-140 T 12-10-2018 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 45 67 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 129 150 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 178 202 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 82 102 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 105 124 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 220 247 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 156 175 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 248 259 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_07020 6b222e04572c1ed8dc8f8a81942e3efe 395 PRINTS PR00688 Xylose isomerase signature 287 298 5.8E-65 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFR_19715 66c79ad9827eb73055c0d12f41658d8f 215 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 11 212 35.357 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_19715 66c79ad9827eb73055c0d12f41658d8f 215 Gene3D G3DSA:3.40.50.10990 16 189 6.9E-61 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_19715 66c79ad9827eb73055c0d12f41658d8f 215 SUPERFAMILY SSF142695 19 187 2.48E-53 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_19715 66c79ad9827eb73055c0d12f41658d8f 215 Pfam PF00925 GTP cyclohydrolase II 31 186 3.9E-59 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFR_10665 753ed43ca1ebc6f46defe0734f3587b5 477 Pfam PF01458 Uncharacterized protein family (UPF0051) 223 448 7.1E-76 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AFR_10665 753ed43ca1ebc6f46defe0734f3587b5 477 SUPERFAMILY SSF101960 44 474 2.62E-139 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily AFR_10665 753ed43ca1ebc6f46defe0734f3587b5 477 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 21 468 2.7E-219 T 12-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 AFR_35490 78ff51d74ea9cea82aa4d33ddde7e462 254 Gene3D G3DSA:3.30.10.20 110 176 3.9E-5 T 12-10-2018 AFR_33125 0f58f54dd6e398ad25c599ce0c5431a8 453 Pfam PF01547 Bacterial extracellular solute-binding protein 58 343 1.7E-24 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_33125 0f58f54dd6e398ad25c599ce0c5431a8 453 Gene3D G3DSA:3.40.190.10 35 452 6.4E-60 T 12-10-2018 AFR_33125 0f58f54dd6e398ad25c599ce0c5431a8 453 SUPERFAMILY SSF53850 23 449 5.74E-49 T 12-10-2018 AFR_15305 22ad768f3e1365504bfae58cb7abe423 287 SUPERFAMILY SSF161098 49 274 5.23E-53 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15305 22ad768f3e1365504bfae58cb7abe423 287 Gene3D G3DSA:1.10.3720.10 47 282 4.5E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15305 22ad768f3e1365504bfae58cb7abe423 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 280 2.5E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_19840 e803f769a73b9c473e064559bc828a67 127 Gene3D G3DSA:1.10.10.10 8 127 1.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19840 e803f769a73b9c473e064559bc828a67 127 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 5.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19840 e803f769a73b9c473e064559bc828a67 127 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 5.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19840 e803f769a73b9c473e064559bc828a67 127 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 5.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19840 e803f769a73b9c473e064559bc828a67 127 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 106 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_19840 e803f769a73b9c473e064559bc828a67 127 SUPERFAMILY SSF46785 14 123 2.93E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_19840 e803f769a73b9c473e064559bc828a67 127 Pfam PF01047 MarR family 38 98 1.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19840 e803f769a73b9c473e064559bc828a67 127 SMART SM00347 31 125 5.0E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11275 fd827138959c4855f2a6b3081dd373b1 405 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFR_11275 fd827138959c4855f2a6b3081dd373b1 405 Gene3D G3DSA:3.40.50.1100 60 386 6.2E-108 T 12-10-2018 AFR_11275 fd827138959c4855f2a6b3081dd373b1 405 Gene3D G3DSA:3.40.50.1100 111 208 6.2E-108 T 12-10-2018 AFR_11275 fd827138959c4855f2a6b3081dd373b1 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 380 7.4E-64 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_11275 fd827138959c4855f2a6b3081dd373b1 405 SUPERFAMILY SSF53686 4 389 2.88E-84 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_22540 3e0df39ddba3dfd0da0635a98b3230bb 439 Gene3D G3DSA:3.40.190.10 44 439 1.8E-88 T 12-10-2018 AFR_22540 3e0df39ddba3dfd0da0635a98b3230bb 439 SUPERFAMILY SSF53850 47 432 6.73E-74 T 12-10-2018 AFR_22540 3e0df39ddba3dfd0da0635a98b3230bb 439 Pfam PF13416 Bacterial extracellular solute-binding protein 65 375 4.5E-40 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_18510 4bf0fcde79a6b8af449bef1198df4253 415 Pfam PF06368 Methylaspartate mutase E chain (MutE) 7 385 1.8E-78 T 12-10-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 AFR_18510 4bf0fcde79a6b8af449bef1198df4253 415 Gene3D G3DSA:3.20.20.240 1 361 2.7E-124 T 12-10-2018 AFR_18510 4bf0fcde79a6b8af449bef1198df4253 415 SUPERFAMILY SSF51703 7 412 3.77E-123 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_18510 4bf0fcde79a6b8af449bef1198df4253 415 PIRSF PIRSF001495 1 415 5.2E-160 T 12-10-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 AFR_18455 083f5d14611fa085225cbadb06122189 518 Pfam PF00732 GMC oxidoreductase 9 289 2.9E-55 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFR_18455 083f5d14611fa085225cbadb06122189 518 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 247 261 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFR_18455 083f5d14611fa085225cbadb06122189 518 Gene3D G3DSA:3.30.410.40 141 444 4.7E-167 T 12-10-2018 AFR_18455 083f5d14611fa085225cbadb06122189 518 Gene3D G3DSA:3.50.50.60 8 503 4.7E-167 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18455 083f5d14611fa085225cbadb06122189 518 PIRSF PIRSF000137 2 324 1.3E-73 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFR_18455 083f5d14611fa085225cbadb06122189 518 PIRSF PIRSF000137 337 513 4.0E-42 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFR_18455 083f5d14611fa085225cbadb06122189 518 Pfam PF05199 GMC oxidoreductase 359 499 3.5E-38 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AFR_18455 083f5d14611fa085225cbadb06122189 518 SUPERFAMILY SSF54373 283 447 2.65E-38 T 12-10-2018 AFR_18455 083f5d14611fa085225cbadb06122189 518 Gene3D G3DSA:4.10.450.10 42 190 4.7E-167 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 AFR_18455 083f5d14611fa085225cbadb06122189 518 Gene3D G3DSA:1.10.1220.110 100 140 4.7E-167 T 12-10-2018 AFR_18455 083f5d14611fa085225cbadb06122189 518 SUPERFAMILY SSF51905 6 507 1.94E-73 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_21170 6cca9219bdae0b31ae68af8b8b5807f9 214 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 21 161 1.0E-9 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system AFR_21975 7e769cc62b2b04afee4eb834a30c7881 778 Pfam PF13768 von Willebrand factor type A domain 299 455 2.3E-17 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_21975 7e769cc62b2b04afee4eb834a30c7881 778 SUPERFAMILY SSF53300 298 474 2.09E-25 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_21975 7e769cc62b2b04afee4eb834a30c7881 778 SMART SM00609 20 148 2.1E-13 T 12-10-2018 IPR013694 VIT domain AFR_21975 7e769cc62b2b04afee4eb834a30c7881 778 Pfam PF08487 Vault protein inter-alpha-trypsin domain 37 144 6.9E-34 T 12-10-2018 IPR013694 VIT domain AFR_21975 7e769cc62b2b04afee4eb834a30c7881 778 Gene3D G3DSA:3.40.50.410 298 474 1.7E-32 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_21975 7e769cc62b2b04afee4eb834a30c7881 778 SMART SM00327 298 472 8.4E-15 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_12785 77c78d24400e502bb647b0519956706f 267 Gene3D G3DSA:1.10.10.1320 1 85 7.3E-6 T 12-10-2018 AFR_04595 1f366fa0b591303a6dc17cfe9bedaea4 60 Gene3D G3DSA:3.30.1390.20 1 60 4.3E-26 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFR_04595 1f366fa0b591303a6dc17cfe9bedaea4 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.0E-24 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04595 1f366fa0b591303a6dc17cfe9bedaea4 60 SUPERFAMILY SSF55129 1 59 1.83E-21 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFR_04595 1f366fa0b591303a6dc17cfe9bedaea4 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.864 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04595 1f366fa0b591303a6dc17cfe9bedaea4 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 2.0E-18 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AFR_04595 1f366fa0b591303a6dc17cfe9bedaea4 60 PIRSF PIRSF002211 1 60 4.4E-28 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_33750 805a5e2535903b2c061f083049b04993 189 SUPERFAMILY SSF46785 17 95 1.54E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_33750 805a5e2535903b2c061f083049b04993 189 Pfam PF12840 Helix-turn-helix domain 23 80 1.1E-12 T 12-10-2018 AFR_33750 805a5e2535903b2c061f083049b04993 189 SMART SM00418 22 101 4.3E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_33750 805a5e2535903b2c061f083049b04993 189 Gene3D G3DSA:1.10.10.10 14 94 7.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04350 1306689d5f4535c8323b809b45c6623b 361 Pfam PF06224 Winged helix DNA-binding domain 31 350 2.3E-70 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 AFR_23280 181a8c9f1d9e681269520a153cd50c63 272 SUPERFAMILY SSF56281 2 233 1.4E-30 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_23280 181a8c9f1d9e681269520a153cd50c63 272 Gene3D G3DSA:3.60.15.10 1 232 2.2E-30 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_23280 181a8c9f1d9e681269520a153cd50c63 272 SMART SM00849 18 210 2.0E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_23280 181a8c9f1d9e681269520a153cd50c63 272 Pfam PF00753 Metallo-beta-lactamase superfamily 16 210 1.5E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 SUPERFAMILY SSF46785 4 62 5.38E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 5.2E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 SMART SM01134 74 236 2.1E-59 T 12-10-2018 AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 Gene3D G3DSA:1.10.10.10 2 105 9.1E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 Pfam PF00455 DeoR C terminal sensor domain 76 234 3.3E-47 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 SUPERFAMILY SSF100950 76 237 2.41E-30 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 SMART SM00420 6 58 2.4E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.1E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_05150 177162e5b34d643dd6c7d9856a9dd1ee 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.1E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFR_34200 1b960f587a8c7ed8f68114f7373e478d 272 SUPERFAMILY SSF53335 15 260 6.22E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_34200 1b960f587a8c7ed8f68114f7373e478d 272 PIRSF PIRSF017393 1 271 8.1E-102 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_34200 1b960f587a8c7ed8f68114f7373e478d 272 Gene3D G3DSA:3.40.50.150 1 271 1.1E-107 T 12-10-2018 AFR_34200 1b960f587a8c7ed8f68114f7373e478d 272 Pfam PF04672 S-adenosyl methyltransferase 7 270 8.4E-104 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_04020 7fb110ce87cba9072b23dff2c5581ade 503 SUPERFAMILY SSF53335 239 461 3.82E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_04020 7fb110ce87cba9072b23dff2c5581ade 503 SUPERFAMILY SSF103473 13 203 2.62E-9 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_04020 7fb110ce87cba9072b23dff2c5581ade 503 Gene3D G3DSA:3.40.50.150 232 499 4.9E-67 T 12-10-2018 AFR_04020 7fb110ce87cba9072b23dff2c5581ade 503 Gene3D G3DSA:1.20.1250.20 7 205 1.1E-7 T 12-10-2018 AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 SUPERFAMILY SSF100939 2 256 1.8E-49 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 257 7.3E-86 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 PIRSF PIRSF006493 1 296 1.8E-97 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 PIRSF PIRSF006493 282 328 4000.0 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 Gene3D G3DSA:2.40.290.10 4 180 3.0E-21 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 174 5.8E-37 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 2 255 32.238 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFR_23265 fed8d12d1e7c13ebc6530668c253b8fe 328 SMART SM00559 53 183 1.5E-31 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AFR_24015 74bdf0498b9309b0b1fc808644ad6a78 476 Gene3D G3DSA:3.40.109.10 267 452 3.8E-13 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_24015 74bdf0498b9309b0b1fc808644ad6a78 476 Gene3D G3DSA:3.40.109.10 39 257 6.2E-46 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_24015 74bdf0498b9309b0b1fc808644ad6a78 476 SUPERFAMILY SSF55469 293 454 7.46E-9 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_24015 74bdf0498b9309b0b1fc808644ad6a78 476 SUPERFAMILY SSF55469 155 241 5.65E-8 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_14020 70c82e8377fdec22791cae0829b54da9 492 Pfam PF03929 PepSY-associated TM region 39 409 1.1E-62 T 12-10-2018 IPR005625 PepSY-associated TM protein AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 Pfam PF00512 His Kinase A (phospho-acceptor) domain 140 202 2.1E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 248 354 4.6E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 SMART SM00304 85 138 3.3E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 SUPERFAMILY SSF55874 211 356 5.89E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 Gene3D G3DSA:1.10.287.130 89 202 3.6E-21 T 12-10-2018 AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 Gene3D G3DSA:3.30.565.10 203 357 8.9E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 SUPERFAMILY SSF47384 125 204 2.94E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 SMART SM00388 139 206 9.8E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_15045 fffe0b012ce2ba25beb1dbcc44fc4cca 360 SMART SM00387 248 360 1.5E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01525 d6f7484b0b144cd26e9574dcb3d60113 254 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_01525 d6f7484b0b144cd26e9574dcb3d60113 254 Gene3D G3DSA:3.40.50.300 1 250 3.3E-66 T 12-10-2018 AFR_01525 d6f7484b0b144cd26e9574dcb3d60113 254 SUPERFAMILY SSF52540 2 227 4.37E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_01525 d6f7484b0b144cd26e9574dcb3d60113 254 SMART SM00382 26 214 3.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01525 d6f7484b0b144cd26e9574dcb3d60113 254 Pfam PF00005 ABC transporter 18 165 3.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_31970 9e58cfc9cc315edc5c519de77ffcb744 277 SUPERFAMILY SSF53335 33 255 2.39E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_31970 9e58cfc9cc315edc5c519de77ffcb744 277 Pfam PF08242 Methyltransferase domain 59 153 2.5E-11 T 12-10-2018 IPR013217 Methyltransferase type 12 AFR_31970 9e58cfc9cc315edc5c519de77ffcb744 277 Gene3D G3DSA:3.40.50.150 40 248 8.2E-29 T 12-10-2018 AFR_13140 a1b10898efdd58622534c657cf6edf41 327 SUPERFAMILY SSF46689 269 318 2.99E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13140 a1b10898efdd58622534c657cf6edf41 327 SUPERFAMILY SSF52317 9 197 4.87E-33 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_13140 a1b10898efdd58622534c657cf6edf41 327 Pfam PF01965 DJ-1/PfpI family 9 175 5.4E-9 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_13140 a1b10898efdd58622534c657cf6edf41 327 SMART SM00342 232 315 2.5E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_13140 a1b10898efdd58622534c657cf6edf41 327 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_13140 a1b10898efdd58622534c657cf6edf41 327 Gene3D G3DSA:1.10.10.60 215 323 1.6E-27 T 12-10-2018 AFR_13140 a1b10898efdd58622534c657cf6edf41 327 SUPERFAMILY SSF46689 217 266 1.22E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13140 a1b10898efdd58622534c657cf6edf41 327 Gene3D G3DSA:3.40.50.880 6 209 1.7E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_13140 a1b10898efdd58622534c657cf6edf41 327 Pfam PF12833 Helix-turn-helix domain 238 317 9.0E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_33720 d821f355e289263578fa04550fee794f 361 Gene3D G3DSA:2.40.10.10 160 354 1.1E-28 T 12-10-2018 AFR_33720 d821f355e289263578fa04550fee794f 361 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 303 314 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site AFR_33720 d821f355e289263578fa04550fee794f 361 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 180 185 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_33720 d821f355e289263578fa04550fee794f 361 SUPERFAMILY SSF50494 160 349 6.51E-18 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_33720 d821f355e289263578fa04550fee794f 361 Gene3D G3DSA:2.40.10.10 237 345 1.1E-28 T 12-10-2018 AFR_33720 d821f355e289263578fa04550fee794f 361 Pfam PF00089 Trypsin 177 333 5.8E-5 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_27380 e02aa4c2ec72a4eb6fcff82fdb9855ba 347 Gene3D G3DSA:3.40.50.720 1 138 2.6E-32 T 12-10-2018 AFR_27380 e02aa4c2ec72a4eb6fcff82fdb9855ba 347 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 116 3.5E-15 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_27380 e02aa4c2ec72a4eb6fcff82fdb9855ba 347 Gene3D G3DSA:3.30.360.10 139 312 3.6E-23 T 12-10-2018 AFR_27380 e02aa4c2ec72a4eb6fcff82fdb9855ba 347 SUPERFAMILY SSF55347 123 252 1.64E-19 T 12-10-2018 AFR_27380 e02aa4c2ec72a4eb6fcff82fdb9855ba 347 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 191 1.1E-4 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_27380 e02aa4c2ec72a4eb6fcff82fdb9855ba 347 SUPERFAMILY SSF51735 3 146 1.25E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_33885 c3a78e1890d967c90eefabfdef758149 309 SUPERFAMILY SSF53850 68 295 9.77E-22 T 12-10-2018 AFR_33885 c3a78e1890d967c90eefabfdef758149 309 Gene3D G3DSA:3.40.190.10 162 260 7.1E-19 T 12-10-2018 AFR_33885 c3a78e1890d967c90eefabfdef758149 309 Pfam PF14503 YhfZ C-terminal domain 69 302 4.5E-56 T 12-10-2018 IPR032791 Uncharacterised protein YhfZ, C-terminal domain AFR_33885 c3a78e1890d967c90eefabfdef758149 309 Gene3D G3DSA:1.10.10.10 4 71 1.3E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33885 c3a78e1890d967c90eefabfdef758149 309 Pfam PF14502 Helix-turn-helix domain 18 64 1.2E-10 T 12-10-2018 AFR_33885 c3a78e1890d967c90eefabfdef758149 309 SUPERFAMILY SSF46785 17 73 5.62E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_33885 c3a78e1890d967c90eefabfdef758149 309 Gene3D G3DSA:3.40.190.10 108 298 7.1E-19 T 12-10-2018 AFR_33445 66e829b43bbe6089b671293b8cf4edac 634 Pfam PF00664 ABC transporter transmembrane region 33 344 5.6E-59 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_33445 66e829b43bbe6089b671293b8cf4edac 634 Pfam PF00005 ABC transporter 407 555 1.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_33445 66e829b43bbe6089b671293b8cf4edac 634 Gene3D G3DSA:3.40.50.300 386 633 1.2E-91 T 12-10-2018 AFR_33445 66e829b43bbe6089b671293b8cf4edac 634 SUPERFAMILY SSF52540 382 626 3.74E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33445 66e829b43bbe6089b671293b8cf4edac 634 SUPERFAMILY SSF90123 15 377 8.76E-87 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_33445 66e829b43bbe6089b671293b8cf4edac 634 SMART SM00382 415 601 6.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33445 66e829b43bbe6089b671293b8cf4edac 634 ProSitePatterns PS00211 ABC transporters family signature. 527 541 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_33695 6ef39c6cdedb40357e95ae479d7df354 1080 Gene3D G3DSA:2.70.98.10 34 354 2.5E-249 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFR_33695 6ef39c6cdedb40357e95ae479d7df354 1080 Pfam PF07971 Glycosyl hydrolase family 92 242 754 2.0E-153 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 AFR_33695 6ef39c6cdedb40357e95ae479d7df354 1080 Gene3D G3DSA:3.30.2080.10 302 758 2.5E-249 T 12-10-2018 AFR_33695 6ef39c6cdedb40357e95ae479d7df354 1080 Gene3D G3DSA:1.20.1610.10 452 632 2.5E-249 T 12-10-2018 AFR_33695 6ef39c6cdedb40357e95ae479d7df354 1080 Gene3D G3DSA:1.20.1050.60 355 451 2.5E-249 T 12-10-2018 AFR_33695 6ef39c6cdedb40357e95ae479d7df354 1080 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 3 757 4.2E-167 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative AFR_33695 6ef39c6cdedb40357e95ae479d7df354 1080 SUPERFAMILY SSF48208 270 738 1.22E-22 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 Gene3D G3DSA:1.10.287.130 89 206 1.5E-22 T 12-10-2018 AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 SUPERFAMILY SSF55874 209 358 1.96E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 SMART SM00388 139 206 5.9E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 248 359 3.2E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 SMART SM00387 248 360 2.6E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 Gene3D G3DSA:3.30.565.10 209 360 1.6E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 SUPERFAMILY SSF47384 122 205 1.63E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 SUPERFAMILY SSF158472 87 135 5.89E-7 T 12-10-2018 AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 Pfam PF00512 His Kinase A (phospho-acceptor) domain 139 206 4.9E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 SMART SM00304 85 138 1.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_30775 ec05f6306f670d1b60b90a1b6fa6bcef 361 Pfam PF00672 HAMP domain 86 134 8.9E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_35625 1149a7781bef6235d99a301d1c051eeb 73 Pfam PF01361 Tautomerase enzyme 7 66 1.5E-15 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 AFR_35625 1149a7781bef6235d99a301d1c051eeb 73 Gene3D G3DSA:3.30.429.10 5 66 2.2E-14 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily AFR_35625 1149a7781bef6235d99a301d1c051eeb 73 SUPERFAMILY SSF55331 7 69 2.5E-12 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily AFR_04420 1232abb44bd4cc017abac914bf7ff554 125 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 70 121 3.5E-20 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 AFR_04420 1232abb44bd4cc017abac914bf7ff554 125 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 71 119 5.4E-21 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04420 1232abb44bd4cc017abac914bf7ff554 125 Gene3D G3DSA:1.20.5.1030 66 121 6.1E-19 T 12-10-2018 IPR038379 SecE superfamily AFR_04420 1232abb44bd4cc017abac914bf7ff554 125 Hamap MF_00422 Protein translocase subunit SecE [secE]. 66 121 13.413 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_04420 1232abb44bd4cc017abac914bf7ff554 125 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 71 99 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFR_40380 8d85d2f8b42ed027340c7524654a1b13 132 SUPERFAMILY SSF141457 10 127 6.67E-31 T 12-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily AFR_40380 8d85d2f8b42ed027340c7524654a1b13 132 Gene3D G3DSA:2.30.290.10 5 131 7.8E-32 T 12-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily AFR_40380 8d85d2f8b42ed027340c7524654a1b13 132 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 9 131 19.188 T 12-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 AFR_40380 8d85d2f8b42ed027340c7524654a1b13 132 Pfam PF02623 FliW protein 11 126 2.7E-30 T 12-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 AFR_37115 ca1e7e475c1c1920927e9328ae9a12c8 256 SUPERFAMILY SSF46689 36 119 3.34E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37115 ca1e7e475c1c1920927e9328ae9a12c8 256 Gene3D G3DSA:1.10.357.10 41 254 2.6E-79 T 12-10-2018 AFR_37115 ca1e7e475c1c1920927e9328ae9a12c8 256 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 62 5.1E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37115 ca1e7e475c1c1920927e9328ae9a12c8 256 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 70 93 5.1E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37115 ca1e7e475c1c1920927e9328ae9a12c8 256 ProSitePatterns PS01081 TetR-type HTH domain signature. 61 92 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_37115 ca1e7e475c1c1920927e9328ae9a12c8 256 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 92 4.8E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37115 ca1e7e475c1c1920927e9328ae9a12c8 256 SUPERFAMILY SSF48498 115 254 8.45E-47 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_28585 b98973f3b4ff7fbfadcc9cdb1d069704 419 SUPERFAMILY SSF81606 187 381 2.62E-10 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_28585 b98973f3b4ff7fbfadcc9cdb1d069704 419 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 202 382 9.4E-36 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_28585 b98973f3b4ff7fbfadcc9cdb1d069704 419 SUPERFAMILY SSF55781 13 135 3.48E-5 T 12-10-2018 AFR_28585 b98973f3b4ff7fbfadcc9cdb1d069704 419 Gene3D G3DSA:3.60.40.10 171 384 2.4E-42 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_28585 b98973f3b4ff7fbfadcc9cdb1d069704 419 SMART SM00331 173 382 1.5E-22 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_18115 b36fb15be5b21c9e4229482a333f5aa9 166 Pfam PF13460 NAD(P)H-binding 7 116 3.1E-9 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_18115 b36fb15be5b21c9e4229482a333f5aa9 166 Gene3D G3DSA:3.40.50.720 1 157 1.2E-18 T 12-10-2018 AFR_18115 b36fb15be5b21c9e4229482a333f5aa9 166 SUPERFAMILY SSF51735 1 145 5.88E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_25275 80af976bf24f495dd62666ae435968cf 337 Gene3D G3DSA:3.40.50.2300 144 269 1.5E-70 T 12-10-2018 AFR_25275 80af976bf24f495dd62666ae435968cf 337 Gene3D G3DSA:3.40.50.2300 44 285 1.5E-70 T 12-10-2018 AFR_25275 80af976bf24f495dd62666ae435968cf 337 Pfam PF13377 Periplasmic binding protein-like domain 152 308 8.4E-34 T 12-10-2018 AFR_25275 80af976bf24f495dd62666ae435968cf 337 SMART SM00354 1 59 4.7E-11 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_25275 80af976bf24f495dd62666ae435968cf 337 Gene3D G3DSA:1.10.260.40 1 43 8.4E-14 T 12-10-2018 AFR_25275 80af976bf24f495dd62666ae435968cf 337 SUPERFAMILY SSF53822 50 312 7.92E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_25275 80af976bf24f495dd62666ae435968cf 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 36 2.6E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFR_25275 80af976bf24f495dd62666ae435968cf 337 SUPERFAMILY SSF47413 1 47 5.72E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_21550 41222b54c540ef215e3f07a905ab6805 499 Pfam PF00561 alpha/beta hydrolase fold 94 232 1.4E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21550 41222b54c540ef215e3f07a905ab6805 499 Pfam PF08386 TAP-like protein 413 482 2.5E-8 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal AFR_21550 41222b54c540ef215e3f07a905ab6805 499 SUPERFAMILY SSF53474 89 480 1.0E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18290 2c642a0b617ab60d9377f1088da1c336 384 SUPERFAMILY SSF51569 55 329 3.91E-11 T 12-10-2018 AFR_18290 2c642a0b617ab60d9377f1088da1c336 384 Pfam PF06187 Protein of unknown function (DUF993) 19 381 6.6E-169 T 12-10-2018 IPR009334 Protein of unknown function DUF993 AFR_18290 2c642a0b617ab60d9377f1088da1c336 384 Gene3D G3DSA:3.20.20.500 8 377 1.1E-161 T 12-10-2018 AFR_26060 d89418b8dc501fcc646c1c764b70421e 383 Pfam PF10979 Protein of unknown function (DUF2786) 168 205 2.3E-15 T 12-10-2018 IPR024498 Domain of unknown function DUF2786 AFR_26060 d89418b8dc501fcc646c1c764b70421e 383 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 168 382 3.0E-47 T 12-10-2018 AFR_24990 81cb9d739fdfe88277898dad24cdb21c 304 Gene3D G3DSA:2.115.10.20 10 135 6.6E-7 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_24990 81cb9d739fdfe88277898dad24cdb21c 304 SUPERFAMILY SSF75005 29 296 5.5E-20 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_24990 81cb9d739fdfe88277898dad24cdb21c 304 Gene3D G3DSA:2.115.10.20 140 303 1.5E-12 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 SUPERFAMILY SSF58104 220 514 1.31E-61 T 12-10-2018 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 482 4.6E-33 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 Pfam PF00672 HAMP domain 200 249 4.1E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 435 464 3.3E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 281 310 3.3E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 387 416 3.3E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 358 385 3.3E-20 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 Gene3D G3DSA:1.10.287.950 199 515 4.6E-65 T 12-10-2018 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 SMART SM00283 260 514 1.9E-53 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_40365 3b333a9da94d8c2fe299afa699f9ba23 515 SMART SM00304 200 252 1.1E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_06415 5c644862949c8e6a9ee13d1b76521b5b 424 SUPERFAMILY SSF51338 337 422 3.84E-12 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_06415 5c644862949c8e6a9ee13d1b76521b5b 424 Gene3D G3DSA:2.30.40.10 8 408 6.4E-136 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_06415 5c644862949c8e6a9ee13d1b76521b5b 424 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 2 413 8.7E-133 T 12-10-2018 IPR010252 Formiminoglutamate deiminase AFR_06415 5c644862949c8e6a9ee13d1b76521b5b 424 Gene3D G3DSA:3.20.20.140 49 414 6.4E-136 T 12-10-2018 AFR_06415 5c644862949c8e6a9ee13d1b76521b5b 424 Pfam PF01979 Amidohydrolase family 44 403 1.3E-38 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_06415 5c644862949c8e6a9ee13d1b76521b5b 424 SUPERFAMILY SSF51556 47 350 3.52E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_18285 6a39ecfb807e0ae1facb008299c1dc6d 384 SUPERFAMILY SSF51735 49 174 9.85E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_18285 6a39ecfb807e0ae1facb008299c1dc6d 384 SUPERFAMILY SSF55347 147 347 2.62E-30 T 12-10-2018 AFR_18285 6a39ecfb807e0ae1facb008299c1dc6d 384 Gene3D G3DSA:3.30.360.10 142 383 1.3E-67 T 12-10-2018 AFR_18285 6a39ecfb807e0ae1facb008299c1dc6d 384 Gene3D G3DSA:3.40.50.720 2 141 6.9E-32 T 12-10-2018 AFR_18285 6a39ecfb807e0ae1facb008299c1dc6d 384 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 36 138 1.5E-8 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_42450 de2fb7674a724790cab2eafb75f97efb 533 Pfam PF13777 Domain of unknown function (DUF4173) 288 477 6.2E-65 T 12-10-2018 IPR025231 Domain of unknown function DUF4173 AFR_40130 0a66f1e41806842fb6bfcd49d58f8c80 348 Gene3D G3DSA:3.40.50.970 83 219 3.2E-26 T 12-10-2018 AFR_40130 0a66f1e41806842fb6bfcd49d58f8c80 348 SUPERFAMILY SSF52518 6 330 8.65E-81 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_40130 0a66f1e41806842fb6bfcd49d58f8c80 348 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 59 206 4.3E-30 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFR_11185 8bd7f48b48692f7f54a67d2ca30364c1 435 Pfam PF13416 Bacterial extracellular solute-binding protein 65 375 5.0E-38 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_11185 8bd7f48b48692f7f54a67d2ca30364c1 435 Gene3D G3DSA:3.40.190.10 156 428 4.5E-68 T 12-10-2018 AFR_11185 8bd7f48b48692f7f54a67d2ca30364c1 435 Gene3D G3DSA:3.40.190.10 64 389 4.5E-68 T 12-10-2018 AFR_11185 8bd7f48b48692f7f54a67d2ca30364c1 435 SUPERFAMILY SSF53850 19 432 9.45E-70 T 12-10-2018 AFR_41025 e147760144a8f58808c947ed786dcfe7 308 Gene3D G3DSA:3.30.420.40 7 297 2.4E-79 T 12-10-2018 AFR_41025 e147760144a8f58808c947ed786dcfe7 308 Gene3D G3DSA:3.30.420.40 131 284 2.4E-79 T 12-10-2018 AFR_41025 e147760144a8f58808c947ed786dcfe7 308 Pfam PF00480 ROK family 7 302 5.2E-55 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_41025 e147760144a8f58808c947ed786dcfe7 308 SUPERFAMILY SSF53067 6 304 1.09E-52 T 12-10-2018 AFR_39255 59ae3c1dd063793a1f6998f15484fa8e 277 Gene3D G3DSA:3.30.70.1020 116 188 7.8E-30 T 12-10-2018 AFR_39255 59ae3c1dd063793a1f6998f15484fa8e 277 SUPERFAMILY SSF56784 35 270 5.68E-27 T 12-10-2018 IPR036412 HAD-like superfamily AFR_39255 59ae3c1dd063793a1f6998f15484fa8e 277 Gene3D G3DSA:3.40.50.1000 35 248 7.8E-30 T 12-10-2018 IPR023214 HAD superfamily AFR_39255 59ae3c1dd063793a1f6998f15484fa8e 277 Pfam PF02358 Trehalose-phosphatase 36 254 5.1E-24 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 AFR_39255 59ae3c1dd063793a1f6998f15484fa8e 277 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 32 268 2.5E-29 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 AFR_16350 b87a7adfbb57e4073d7b3fedb8ccddf9 242 Gene3D G3DSA:3.60.15.10 51 238 2.4E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_16350 b87a7adfbb57e4073d7b3fedb8ccddf9 242 Pfam PF00753 Metallo-beta-lactamase superfamily 56 221 1.2E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_16350 b87a7adfbb57e4073d7b3fedb8ccddf9 242 SMART SM00849 58 221 3.0E-30 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_16350 b87a7adfbb57e4073d7b3fedb8ccddf9 242 SUPERFAMILY SSF56281 56 231 2.3E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_16375 2452b6f1bde30ab402d99fbaaee6615d 331 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 1.2E-145 T 12-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 AFR_16375 2452b6f1bde30ab402d99fbaaee6615d 331 Gene3D G3DSA:3.30.1180.20 185 331 5.9E-52 T 12-10-2018 AFR_16375 2452b6f1bde30ab402d99fbaaee6615d 331 Pfam PF02733 Dak1 domain 17 328 5.0E-132 T 12-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_16375 2452b6f1bde30ab402d99fbaaee6615d 331 SUPERFAMILY SSF82549 10 331 7.06E-122 T 12-10-2018 AFR_16375 2452b6f1bde30ab402d99fbaaee6615d 331 Gene3D G3DSA:3.40.50.10440 11 184 2.6E-64 T 12-10-2018 AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 Gene3D G3DSA:3.40.50.720 1 245 3.4E-57 T 12-10-2018 AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 7 237 5.6E-46 T 12-10-2018 AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 5.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 5.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 5.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 SUPERFAMILY SSF51735 1 240 3.4E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 3.4E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 3.4E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 3.4E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 3.4E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 3.4E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_06195 5a3af4803e1c9c9082ef43aa825473e5 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_24200 6383840dd32027a88aea5c83fb9dc697 414 Gene3D G3DSA:3.30.565.10 291 410 2.2E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24200 6383840dd32027a88aea5c83fb9dc697 414 SUPERFAMILY SSF55874 309 409 9.2E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24200 6383840dd32027a88aea5c83fb9dc697 414 Pfam PF13796 Putative sensor 21 199 2.8E-28 T 12-10-2018 IPR025828 Putative sensor domain AFR_24200 6383840dd32027a88aea5c83fb9dc697 414 Pfam PF07730 Histidine kinase 224 289 1.1E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_10425 4c968e1cd661c42dd69da71f211e1cc9 250 SMART SM00382 26 223 1.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_10425 4c968e1cd661c42dd69da71f211e1cc9 250 Gene3D G3DSA:3.40.50.300 1 249 8.3E-79 T 12-10-2018 AFR_10425 4c968e1cd661c42dd69da71f211e1cc9 250 Pfam PF00005 ABC transporter 17 175 3.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_10425 4c968e1cd661c42dd69da71f211e1cc9 250 SUPERFAMILY SSF52540 1 245 7.06E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_10425 4c968e1cd661c42dd69da71f211e1cc9 250 PIRSF PIRSF039085 1 250 1.8E-124 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFR_10425 4c968e1cd661c42dd69da71f211e1cc9 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_13385 b6037f58d0f9312b315d48cc763c478b 481 SUPERFAMILY SSF103473 8 462 2.35E-64 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_13385 b6037f58d0f9312b315d48cc763c478b 481 Pfam PF07690 Major Facilitator Superfamily 15 405 4.4E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_13385 b6037f58d0f9312b315d48cc763c478b 481 Gene3D G3DSA:1.20.1250.20 256 457 2.4E-12 T 12-10-2018 AFR_13385 b6037f58d0f9312b315d48cc763c478b 481 Gene3D G3DSA:1.20.1720.10 10 216 6.7E-54 T 12-10-2018 AFR_13385 b6037f58d0f9312b315d48cc763c478b 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 6.0E-7 T 12-10-2018 AFR_13385 b6037f58d0f9312b315d48cc763c478b 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 6.0E-7 T 12-10-2018 AFR_13385 b6037f58d0f9312b315d48cc763c478b 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 6.0E-7 T 12-10-2018 AFR_18205 12ea2a98e23ef5c7551a5be11f134660 110 SUPERFAMILY SSF57716 81 110 2.35E-7 T 12-10-2018 AFR_18205 12ea2a98e23ef5c7551a5be11f134660 110 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 84 108 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site AFR_18205 12ea2a98e23ef5c7551a5be11f134660 110 Gene3D G3DSA:1.20.120.910 1 110 3.3E-25 T 12-10-2018 AFR_18205 12ea2a98e23ef5c7551a5be11f134660 110 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 79 110 1.4E-11 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 Pfam PF13343 Bacterial extracellular solute-binding protein 128 362 1.1E-30 T 12-10-2018 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 Gene3D G3DSA:3.40.190.10 184 309 1.6E-84 T 12-10-2018 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 Gene3D G3DSA:3.40.190.10 75 364 1.6E-84 T 12-10-2018 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 SUPERFAMILY SSF53850 70 411 2.38E-61 T 12-10-2018 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 218 237 1.3E-16 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 126 140 1.3E-16 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 175 191 1.3E-16 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 200 214 1.3E-16 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFR_06650 b518f96ef0858bcbee85d77b5678d627 417 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 302 321 1.3E-16 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFR_14275 0f93bbc4e6cd2a297eea87103f2e8f5b 700 SUPERFAMILY SSF82866 115 334 3.53E-24 T 12-10-2018 AFR_14275 0f93bbc4e6cd2a297eea87103f2e8f5b 700 SUPERFAMILY SSF82866 452 685 4.84E-22 T 12-10-2018 AFR_14275 0f93bbc4e6cd2a297eea87103f2e8f5b 700 Pfam PF03176 MMPL family 44 361 5.4E-36 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_14275 0f93bbc4e6cd2a297eea87103f2e8f5b 700 Pfam PF03176 MMPL family 466 695 1.4E-26 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_16080 4e15f58c200d39736e2476c040aff5c9 411 Pfam PF07690 Major Facilitator Superfamily 8 353 9.0E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_16080 4e15f58c200d39736e2476c040aff5c9 411 Gene3D G3DSA:1.20.1250.20 2 389 1.4E-30 T 12-10-2018 AFR_16080 4e15f58c200d39736e2476c040aff5c9 411 SUPERFAMILY SSF103473 3 389 4.19E-35 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_27490 fa5c88f09d3899ffe511ed9398acc234 133 Gene3D G3DSA:3.10.450.50 2 132 7.6E-31 T 12-10-2018 AFR_27490 fa5c88f09d3899ffe511ed9398acc234 133 SUPERFAMILY SSF54427 2 130 1.25E-23 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_27490 fa5c88f09d3899ffe511ed9398acc234 133 Pfam PF12680 SnoaL-like domain 22 118 5.6E-13 T 12-10-2018 IPR037401 SnoaL-like domain AFR_37710 b211a91d524aac0f48183090b806e6f8 186 SUPERFAMILY SSF46689 6 72 4.59E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37710 b211a91d524aac0f48183090b806e6f8 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 9.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37710 b211a91d524aac0f48183090b806e6f8 186 Gene3D G3DSA:1.10.357.10 1 185 3.1E-14 T 12-10-2018 AFR_24180 e561ca9aeb2d1526912fdda237580989 291 Pfam PF01636 Phosphotransferase enzyme family 31 235 9.2E-14 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_24180 e561ca9aeb2d1526912fdda237580989 291 SUPERFAMILY SSF56112 13 230 4.23E-23 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_18555 72be1412348c747235e984f8b45917a4 70 SMART SM00923 4 54 4.2E-29 T 12-10-2018 IPR005153 MbtH-like domain AFR_18555 72be1412348c747235e984f8b45917a4 70 SUPERFAMILY SSF160582 3 69 7.45E-30 T 12-10-2018 IPR038020 MbtH-like domain superfamily AFR_18555 72be1412348c747235e984f8b45917a4 70 Gene3D G3DSA:3.90.820.10 1 70 5.9E-34 T 12-10-2018 AFR_18555 72be1412348c747235e984f8b45917a4 70 Pfam PF03621 MbtH-like protein 2 53 6.0E-27 T 12-10-2018 IPR005153 MbtH-like domain AFR_35830 aca96759fe9203be064cbbb0b509a24f 129 Pfam PF10861 Protein of Unknown function (DUF2784) 5 111 5.4E-28 T 12-10-2018 IPR021218 Protein of unknown function DUF2784 AFR_09430 8d547ff71127979753bc8097d40dba00 367 SUPERFAMILY SSF50022 284 366 6.81E-25 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_09430 8d547ff71127979753bc8097d40dba00 367 Gene3D G3DSA:2.102.10.10 209 364 9.1E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_09430 8d547ff71127979753bc8097d40dba00 367 Pfam PF00355 Rieske [2Fe-2S] domain 284 340 9.2E-9 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 SMART SM00421 152 209 2.3E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 Pfam PF00072 Response regulator receiver domain 5 118 9.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 4.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 4.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 4.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 Gene3D G3DSA:3.40.50.12740 3 214 6.7E-67 T 12-10-2018 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 SUPERFAMILY SSF52172 2 135 1.99E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 SMART SM00448 3 117 2.0E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 SUPERFAMILY SSF46894 145 214 8.5E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_12540 6bcbe130db968a3141b58a4d09e46c22 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.4E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 8.2E-43 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 SUPERFAMILY SSF51735 164 300 5.23E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 299 3.4E-29 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 Gene3D G3DSA:3.40.50.720 162 306 1.8E-40 T 12-10-2018 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 Gene3D G3DSA:3.30.460.30 1 158 3.0E-52 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 SUPERFAMILY SSF69742 1 158 3.01E-42 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 PIRSF PIRSF000445 1 426 2.3E-138 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 SUPERFAMILY SSF69075 313 414 1.7E-18 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 414 3.4E-125 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 411 26.465 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_40180 3df93b493922b6d3e825f003e7f68b4c 431 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 315 413 7.4E-24 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 Gene3D G3DSA:3.40.50.720 1 265 1.1E-69 T 12-10-2018 AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 Pfam PF00106 short chain dehydrogenase 3 185 4.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.1E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.1E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.1E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.1E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 SUPERFAMILY SSF51735 1 245 1.85E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_37545 f811721629b3bd40bfacb6b00008ed56 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 175 0.0038 T 12-10-2018 AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 9.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 9.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 9.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 9.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 9.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 9.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 8.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 8.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 8.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 SUPERFAMILY SSF51735 4 249 9.12E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 Gene3D G3DSA:3.40.50.720 2 279 5.5E-77 T 12-10-2018 AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 Pfam PF00106 short chain dehydrogenase 5 190 2.1E-52 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_28715 eef5ffdbe50d8e7a9d3c29847267d106 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.7E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.7E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 41 2.7E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.7E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 SMART SM00418 9 90 9.9E-25 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 Pfam PF12840 Helix-turn-helix domain 9 67 6.9E-16 T 12-10-2018 AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 Gene3D G3DSA:1.10.10.10 1 89 9.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39070 2a2a01da8ad91a7967c96b65f83d1bdf 93 SUPERFAMILY SSF46785 6 89 1.36E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01320 c21ad8c0abf228be93fed91aa067cc06 445 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 19 433 8.3E-178 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFR_01320 c21ad8c0abf228be93fed91aa067cc06 445 Gene3D G3DSA:3.40.640.10 84 329 1.7E-157 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_01320 c21ad8c0abf228be93fed91aa067cc06 445 SUPERFAMILY SSF53383 17 433 7.17E-116 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_01320 c21ad8c0abf228be93fed91aa067cc06 445 Gene3D G3DSA:3.90.1150.10 22 428 1.7E-157 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_01320 c21ad8c0abf228be93fed91aa067cc06 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 283 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_01320 c21ad8c0abf228be93fed91aa067cc06 445 Pfam PF00202 Aminotransferase class-III 48 429 1.4E-80 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_01320 c21ad8c0abf228be93fed91aa067cc06 445 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 18 437 97.066 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFR_18895 4f383cf7ff51ee09437e891cef718c1c 322 SUPERFAMILY SSF69304 99 311 5.1E-13 T 12-10-2018 AFR_18895 4f383cf7ff51ee09437e891cef718c1c 322 Pfam PF07676 WD40-like Beta Propeller Repeat 226 239 0.0089 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFR_18895 4f383cf7ff51ee09437e891cef718c1c 322 Gene3D G3DSA:2.120.10.30 162 320 1.4E-13 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_01515 db9839cf719c37ffe9d9004b06a7bde1 268 Pfam PF01497 Periplasmic binding protein 15 243 5.8E-36 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFR_01515 db9839cf719c37ffe9d9004b06a7bde1 268 Gene3D G3DSA:3.40.50.1980 2 127 6.6E-33 T 12-10-2018 AFR_01515 db9839cf719c37ffe9d9004b06a7bde1 268 Gene3D G3DSA:3.40.50.1980 129 265 1.0E-35 T 12-10-2018 AFR_01515 db9839cf719c37ffe9d9004b06a7bde1 268 SUPERFAMILY SSF53807 4 262 1.22E-58 T 12-10-2018 AFR_17610 8b7ada849560dc410b926d666fab328e 558 Pfam PF01547 Bacterial extracellular solute-binding protein 128 362 1.0E-17 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_17610 8b7ada849560dc410b926d666fab328e 558 SUPERFAMILY SSF53850 108 548 1.52E-56 T 12-10-2018 AFR_17610 8b7ada849560dc410b926d666fab328e 558 Gene3D G3DSA:3.40.190.10 228 440 1.9E-30 T 12-10-2018 AFR_17610 8b7ada849560dc410b926d666fab328e 558 Gene3D G3DSA:3.40.190.10 105 225 1.4E-5 T 12-10-2018 AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 184 0.0017 T 12-10-2018 AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 Gene3D G3DSA:3.40.50.720 3 236 1.2E-64 T 12-10-2018 AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 SUPERFAMILY SSF51735 3 225 3.13E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 Pfam PF00106 short chain dehydrogenase 5 191 1.1E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13540 e1d121cca9ad61dc1302bc36bfefd542 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.3E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_35575 4a89678376b773f95485045a03026a7e 111 Pfam PF01638 HxlR-like helix-turn-helix 15 102 5.5E-33 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_35575 4a89678376b773f95485045a03026a7e 111 Gene3D G3DSA:1.10.10.10 2 110 1.9E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35575 4a89678376b773f95485045a03026a7e 111 SUPERFAMILY SSF46785 3 101 1.23E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01370 399549ee55621ec51ab8040d56ee7162 451 Gene3D G3DSA:3.40.190.10 31 450 6.2E-53 T 12-10-2018 AFR_01370 399549ee55621ec51ab8040d56ee7162 451 SUPERFAMILY SSF53850 19 448 6.04E-47 T 12-10-2018 AFR_01370 399549ee55621ec51ab8040d56ee7162 451 Pfam PF01547 Bacterial extracellular solute-binding protein 54 317 4.2E-23 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_18970 426fa0315ab514dd1c1336461a0fe5bb 292 Pfam PF00296 Luciferase-like monooxygenase 15 227 1.3E-45 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_18970 426fa0315ab514dd1c1336461a0fe5bb 292 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 23 265 8.2E-59 T 12-10-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted AFR_18970 426fa0315ab514dd1c1336461a0fe5bb 292 Gene3D G3DSA:3.20.20.30 1 286 3.9E-68 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_18970 426fa0315ab514dd1c1336461a0fe5bb 292 SUPERFAMILY SSF51679 3 273 1.14E-58 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_27690 12ecc650f7ddcab6f5d90b234ceb2edb 393 Pfam PF02687 FtsX-like permease family 299 387 9.3E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_27690 12ecc650f7ddcab6f5d90b234ceb2edb 393 Pfam PF12704 MacB-like periplasmic core domain 27 237 1.3E-14 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_42605 c001d6052d4ee8645c5a75d003152637 191 Pfam PF10759 Protein of unknown function (DUF2587) 35 191 1.7E-73 T 12-10-2018 IPR019695 Bacterial proteasome activator GO:0061136 AFR_31040 60ac098ef0ba1d7ab9f82d6c35bba300 180 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 15 178 8.4E-59 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 AFR_31040 60ac098ef0ba1d7ab9f82d6c35bba300 180 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 13 180 34.75 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 AFR_31040 60ac098ef0ba1d7ab9f82d6c35bba300 180 Gene3D G3DSA:3.40.50.2020 2 180 6.8E-59 T 12-10-2018 AFR_31040 60ac098ef0ba1d7ab9f82d6c35bba300 180 SUPERFAMILY SSF53271 20 174 1.38E-47 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_31040 60ac098ef0ba1d7ab9f82d6c35bba300 180 Pfam PF00156 Phosphoribosyl transferase domain 46 159 6.2E-16 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFR_04040 13a18e4316beef5870acdafa0b7db1ef 406 Pfam PF05977 Transmembrane secretion effector 11 390 1.2E-37 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_04040 13a18e4316beef5870acdafa0b7db1ef 406 SUPERFAMILY SSF103473 15 393 2.75E-40 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_04040 13a18e4316beef5870acdafa0b7db1ef 406 Gene3D G3DSA:1.20.1250.20 11 393 8.5E-37 T 12-10-2018 AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 SMART SM00342 218 301 2.8E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 Gene3D G3DSA:3.40.50.880 1 196 1.4E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 Gene3D G3DSA:1.10.10.60 202 305 1.7E-25 T 12-10-2018 AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 SUPERFAMILY SSF52317 1 184 3.15E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 Pfam PF12833 Helix-turn-helix domain 224 302 1.1E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 SUPERFAMILY SSF46689 206 252 6.09E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 SUPERFAMILY SSF46689 255 304 1.34E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_34145 fff01379bcd249db2a160202c96bb6a7 306 Pfam PF01965 DJ-1/PfpI family 1 163 2.9E-22 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_04545 2675936df768e6604e21da771cf96734 78 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 15.941 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04545 2675936df768e6604e21da771cf96734 78 SUPERFAMILY SSF46561 5 67 1.83E-21 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04545 2675936df768e6604e21da771cf96734 78 Pfam PF00831 Ribosomal L29 protein 8 64 2.7E-22 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04545 2675936df768e6604e21da771cf96734 78 Gene3D G3DSA:1.10.287.310 5 69 5.9E-25 T 12-10-2018 AFR_04545 2675936df768e6604e21da771cf96734 78 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 1.6E-19 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_14880 9cbf24d33ec84156725a121a54f3ea4c 303 Pfam PF07859 alpha/beta hydrolase fold 69 275 1.6E-56 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_14880 9cbf24d33ec84156725a121a54f3ea4c 303 SUPERFAMILY SSF53474 47 299 1.8E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14880 9cbf24d33ec84156725a121a54f3ea4c 303 Gene3D G3DSA:3.40.50.1820 4 299 2.1E-77 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01565 cce9225de74b0905deb242daaa51c895 177 ProSitePatterns PS01117 MarR-type HTH domain signature. 37 72 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_01565 cce9225de74b0905deb242daaa51c895 177 Gene3D G3DSA:1.10.10.10 1 112 7.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01565 cce9225de74b0905deb242daaa51c895 177 SMART SM00418 1 88 1.6E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_01565 cce9225de74b0905deb242daaa51c895 177 Pfam PF12840 Helix-turn-helix domain 2 56 3.6E-12 T 12-10-2018 AFR_01565 cce9225de74b0905deb242daaa51c895 177 SUPERFAMILY SSF46785 1 74 1.49E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01150 2bab1b7a456ddb3957cfeede0ae05f74 253 Pfam PF12697 Alpha/beta hydrolase family 20 247 1.4E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01150 2bab1b7a456ddb3957cfeede0ae05f74 253 Gene3D G3DSA:3.40.50.1820 6 253 1.2E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01150 2bab1b7a456ddb3957cfeede0ae05f74 253 SUPERFAMILY SSF53474 9 253 2.53E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01150 2bab1b7a456ddb3957cfeede0ae05f74 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 9.6E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01150 2bab1b7a456ddb3957cfeede0ae05f74 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 9.6E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_01150 2bab1b7a456ddb3957cfeede0ae05f74 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 9.6E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_21295 df1fd1d604db86d898d673363ec81719 113 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 2.1E-18 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_21295 df1fd1d604db86d898d673363ec81719 113 SUPERFAMILY SSF46785 6 99 1.25E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_21295 df1fd1d604db86d898d673363ec81719 113 Gene3D G3DSA:1.10.10.10 2 100 2.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31030 5880312c4821eb88e5dbd16eb3e827f2 277 Gene3D G3DSA:2.40.100.10 100 277 6.4E-33 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_31030 5880312c4821eb88e5dbd16eb3e827f2 277 SUPERFAMILY SSF50891 107 272 4.68E-27 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_31030 5880312c4821eb88e5dbd16eb3e827f2 277 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 110 271 6.2E-24 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 Pfam PF00072 Response regulator receiver domain 6 110 1.4E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 SMART SM00448 3 113 4.3E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 Gene3D G3DSA:3.40.50.2300 2 125 4.1E-35 T 12-10-2018 AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 SUPERFAMILY SSF52172 3 162 2.56E-40 T 12-10-2018 IPR011006 CheY-like superfamily AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 SUPERFAMILY SSF46894 128 225 1.7E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 Gene3D G3DSA:1.10.10.10 126 230 1.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 225 3.9E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_24400 afc2b5c8fed8d97f4ad87eefa2133245 235 SMART SM00862 146 225 5.7E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_30150 dc2a028fff8df35ca7a15d30fc5f8e81 130 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 80 4.9E-11 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AFR_38180 efaf8c9b59647e0b9cf578e0e7bc4c1b 154 SUPERFAMILY SSF55874 63 148 1.15E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38180 efaf8c9b59647e0b9cf578e0e7bc4c1b 154 Gene3D G3DSA:3.30.565.10 29 153 6.3E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38180 efaf8c9b59647e0b9cf578e0e7bc4c1b 154 Pfam PF13581 Histidine kinase-like ATPase domain 40 149 1.4E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_26980 775560e303b1b1e572b1fb02a9f91bd9 553 SUPERFAMILY SSF81606 314 521 4.18E-5 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_26980 775560e303b1b1e572b1fb02a9f91bd9 553 SMART SM00331 300 522 1.2E-33 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_26980 775560e303b1b1e572b1fb02a9f91bd9 553 Gene3D G3DSA:3.30.450.40 132 273 6.9E-10 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_26980 775560e303b1b1e572b1fb02a9f91bd9 553 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 332 522 2.0E-40 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_26980 775560e303b1b1e572b1fb02a9f91bd9 553 SUPERFAMILY SSF55781 114 285 2.84E-9 T 12-10-2018 AFR_26980 775560e303b1b1e572b1fb02a9f91bd9 553 Gene3D G3DSA:3.60.40.10 274 522 2.8E-54 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_20810 4f0144525e1b02679aa63944e4702a14 313 SUPERFAMILY SSF47240 29 271 4.06E-82 T 12-10-2018 IPR009078 Ferritin-like superfamily AFR_20810 4f0144525e1b02679aa63944e4702a14 313 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 9 297 4.1E-153 T 12-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 AFR_20810 4f0144525e1b02679aa63944e4702a14 313 Gene3D G3DSA:1.20.1260.10 2 311 4.1E-131 T 12-10-2018 IPR012347 Ferritin-like AFR_20810 4f0144525e1b02679aa63944e4702a14 313 Pfam PF05138 Phenylacetic acid catabolic protein 19 293 1.0E-100 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 AFR_41565 44c5962864e0635557149531360dba6b 167 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFR_41565 44c5962864e0635557149531360dba6b 167 SUPERFAMILY SSF50324 3 156 7.98E-55 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFR_41565 44c5962864e0635557149531360dba6b 167 Gene3D G3DSA:3.90.80.10 1 162 1.2E-64 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFR_41565 44c5962864e0635557149531360dba6b 167 Pfam PF00719 Inorganic pyrophosphatase 5 157 3.8E-52 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFR_41565 44c5962864e0635557149531360dba6b 167 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 31.993 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFR_17655 c1807d470a2c1be6b5654c0cd62797e9 371 Gene3D G3DSA:3.30.565.10 248 368 4.0E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17655 c1807d470a2c1be6b5654c0cd62797e9 371 Pfam PF07730 Histidine kinase 184 250 8.6E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_17655 c1807d470a2c1be6b5654c0cd62797e9 371 SUPERFAMILY SSF55874 254 360 1.33E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_13300 17162dde3c84c836f31fa50c1f4575b9 326 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 320 9.6E-92 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 AFR_13300 17162dde3c84c836f31fa50c1f4575b9 326 SUPERFAMILY SSF51679 7 321 4.19E-59 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_13300 17162dde3c84c836f31fa50c1f4575b9 326 Gene3D G3DSA:3.20.20.30 3 323 2.2E-77 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_13300 17162dde3c84c836f31fa50c1f4575b9 326 Pfam PF00296 Luciferase-like monooxygenase 13 297 3.6E-37 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_30155 c562704f9ff4e7bb34d10f3cd1a0db69 140 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 98 5.8E-23 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 AFR_30155 c562704f9ff4e7bb34d10f3cd1a0db69 140 Pfam PF03334 Na+/H+ antiporter subunit 12 91 2.7E-25 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 Gene3D G3DSA:1.25.10.110 99 186 9.3E-13 T 12-10-2018 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 Gene3D G3DSA:1.25.10.10 187 345 1.9E-26 T 12-10-2018 IPR011989 Armadillo-like helical AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 Pfam PF13646 HEAT repeats 258 325 2.6E-11 T 12-10-2018 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 Pfam PF13646 HEAT repeats 111 174 6.8E-10 T 12-10-2018 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 SMART SM00567 E-Z type HEAT repeats 239 268 0.0036 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 SMART SM00567 E-Z type HEAT repeats 115 144 0.092 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 SMART SM00567 E-Z type HEAT repeats 146 175 0.64 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 SMART SM00567 E-Z type HEAT repeats 302 330 390.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 SMART SM00567 E-Z type HEAT repeats 207 236 99.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 SMART SM00567 E-Z type HEAT repeats 271 300 1.1E-5 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFR_11575 121556d27f082cfb6e0d7b7ae64e9392 369 SUPERFAMILY SSF48371 118 321 1.84E-34 T 12-10-2018 IPR016024 Armadillo-type fold AFR_41235 a79e4455e1c0b5c9ea1db1c01ebcf347 430 Gene3D G3DSA:3.40.190.10 148 406 9.4E-84 T 12-10-2018 AFR_41235 a79e4455e1c0b5c9ea1db1c01ebcf347 430 Pfam PF01547 Bacterial extracellular solute-binding protein 43 337 5.2E-40 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_41235 a79e4455e1c0b5c9ea1db1c01ebcf347 430 SUPERFAMILY SSF53850 12 426 1.94E-69 T 12-10-2018 AFR_41235 a79e4455e1c0b5c9ea1db1c01ebcf347 430 Gene3D G3DSA:3.40.190.10 36 387 9.4E-84 T 12-10-2018 AFR_39860 9829c03a0e8eac2264a947e650edf9d7 121 SUPERFAMILY SSF54593 2 120 2.02E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_39860 9829c03a0e8eac2264a947e650edf9d7 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 114 7.7E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_39860 9829c03a0e8eac2264a947e650edf9d7 121 Gene3D G3DSA:3.10.180.10 1 121 1.5E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 SUPERFAMILY SSF52540 4 247 3.75E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 259 6.9E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 487 515 2.6E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 SMART SM00382 33 225 5.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 SMART SM00382 302 485 8.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 Pfam PF00005 ABC transporter 294 435 4.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 Pfam PF00005 ABC transporter 25 176 1.0E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 SUPERFAMILY SSF52540 271 513 9.47E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 Gene3D G3DSA:3.40.50.300 2 273 4.5E-72 T 12-10-2018 AFR_22360 c89a65201118e2b4024c2892c41c8f7b 518 Gene3D G3DSA:3.40.50.300 277 518 8.9E-81 T 12-10-2018 AFR_39000 fa22c33fbd1e41c96df373565cf2ebe7 103 SUPERFAMILY SSF55248 14 97 4.71E-5 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFR_24035 8e2516e26f65bd9ced82ade5bd5065cd 306 Gene3D G3DSA:1.10.10.10 1 92 9.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24035 8e2516e26f65bd9ced82ade5bd5065cd 306 SMART SM00418 8 87 1.1E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_24035 8e2516e26f65bd9ced82ade5bd5065cd 306 SUPERFAMILY SSF46785 3 88 4.75E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24035 8e2516e26f65bd9ced82ade5bd5065cd 306 Pfam PF12840 Helix-turn-helix domain 8 67 2.9E-9 T 12-10-2018 AFR_24685 534d1d2a7598d6ac2acbbb9b306711ca 284 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 14 174 1.6E-42 T 12-10-2018 IPR025847 MEDS domain AFR_24685 534d1d2a7598d6ac2acbbb9b306711ca 284 SUPERFAMILY SSF52091 191 274 1.71E-6 T 12-10-2018 IPR036513 STAS domain superfamily AFR_24685 534d1d2a7598d6ac2acbbb9b306711ca 284 Pfam PF13466 STAS domain 197 274 2.8E-8 T 12-10-2018 IPR002645 STAS domain AFR_24685 534d1d2a7598d6ac2acbbb9b306711ca 284 Gene3D G3DSA:3.30.750.24 190 279 2.7E-10 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01995 48e1d478cb27fbdbf1de1a87734072fc 183 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 162 3.4E-10 T 12-10-2018 IPR001451 Hexapeptide repeat AFR_01995 48e1d478cb27fbdbf1de1a87734072fc 183 SMART SM01266 2 56 1.7E-19 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 AFR_01995 48e1d478cb27fbdbf1de1a87734072fc 183 SUPERFAMILY SSF51161 3 181 1.23E-49 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_01995 48e1d478cb27fbdbf1de1a87734072fc 183 Pfam PF12464 Maltose acetyltransferase 4 54 3.6E-14 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 AFR_01995 48e1d478cb27fbdbf1de1a87734072fc 183 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 136 164 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFR_01995 48e1d478cb27fbdbf1de1a87734072fc 183 Gene3D G3DSA:2.160.10.10 1 183 7.2E-63 T 12-10-2018 AFR_28330 2cf801278d546b0151ff47a2df4759fb 158 Gene3D G3DSA:3.40.630.30 3 158 2.5E-31 T 12-10-2018 AFR_28330 2cf801278d546b0151ff47a2df4759fb 158 Pfam PF00583 Acetyltransferase (GNAT) family 55 147 1.7E-14 T 12-10-2018 IPR000182 GNAT domain AFR_28330 2cf801278d546b0151ff47a2df4759fb 158 SUPERFAMILY SSF55729 2 152 3.14E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40330 566bbf7fc19fa16c1f3ec118ea291dd5 548 Pfam PF02156 Glycosyl hydrolase family 26 369 430 1.5E-5 T 12-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 AFR_40330 566bbf7fc19fa16c1f3ec118ea291dd5 548 Gene3D G3DSA:3.20.20.80 245 538 9.2E-50 T 12-10-2018 AFR_40330 566bbf7fc19fa16c1f3ec118ea291dd5 548 SUPERFAMILY SSF51445 263 516 1.88E-24 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_22290 007c1ab2ca8edd01d58e2e3c7c7afb3e 197 SUPERFAMILY SSF46689 2 71 5.64E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_22290 007c1ab2ca8edd01d58e2e3c7c7afb3e 197 Pfam PF13305 WHG domain 78 156 8.4E-13 T 12-10-2018 IPR025996 WHG domain AFR_22290 007c1ab2ca8edd01d58e2e3c7c7afb3e 197 SUPERFAMILY SSF48498 72 161 9.39E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_22290 007c1ab2ca8edd01d58e2e3c7c7afb3e 197 Gene3D G3DSA:1.10.357.10 1 176 1.6E-31 T 12-10-2018 AFR_16545 d2be5b976da1a9a6f81f7d3c25284539 482 Gene3D G3DSA:1.20.200.10 190 472 8.1E-64 T 12-10-2018 AFR_16545 d2be5b976da1a9a6f81f7d3c25284539 482 SUPERFAMILY SSF48557 3 471 2.83E-101 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_16545 d2be5b976da1a9a6f81f7d3c25284539 482 Gene3D G3DSA:1.10.275.10 1 189 2.5E-29 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_16545 d2be5b976da1a9a6f81f7d3c25284539 482 Pfam PF00221 Aromatic amino acid lyase 13 433 1.5E-97 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 AFR_39265 6e7c1bd79a59b9546da62aeff4cdb26e 316 Pfam PF00892 EamA-like transporter family 129 260 5.0E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_39265 6e7c1bd79a59b9546da62aeff4cdb26e 316 SUPERFAMILY SSF103481 169 262 3.14E-11 T 12-10-2018 AFR_39265 6e7c1bd79a59b9546da62aeff4cdb26e 316 SUPERFAMILY SSF103481 31 124 4.32E-7 T 12-10-2018 AFR_25340 746946031201293496b2f2d1b38a0247 618 Gene3D G3DSA:1.20.1090.10 162 338 2.2E-41 T 12-10-2018 AFR_25340 746946031201293496b2f2d1b38a0247 618 Gene3D G3DSA:2.60.130.10 339 615 7.2E-103 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_25340 746946031201293496b2f2d1b38a0247 618 SUPERFAMILY SSF56796 10 324 6.8E-78 T 12-10-2018 AFR_25340 746946031201293496b2f2d1b38a0247 618 Pfam PF04444 Catechol dioxygenase N terminus 354 424 3.4E-25 T 12-10-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 AFR_25340 746946031201293496b2f2d1b38a0247 618 Pfam PF00775 Dioxygenase 433 601 3.7E-47 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 AFR_25340 746946031201293496b2f2d1b38a0247 618 Gene3D G3DSA:3.40.50.1970 1 160 8.3E-40 T 12-10-2018 AFR_25340 746946031201293496b2f2d1b38a0247 618 SUPERFAMILY SSF49482 337 597 1.44E-84 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_25340 746946031201293496b2f2d1b38a0247 618 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 326 3.2E-70 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFR_28240 26668d27314d83edee49743571d925b1 99 Pfam PF01638 HxlR-like helix-turn-helix 3 79 8.6E-21 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_28240 26668d27314d83edee49743571d925b1 99 SUPERFAMILY SSF46785 1 91 1.34E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_28240 26668d27314d83edee49743571d925b1 99 Gene3D G3DSA:1.10.10.10 1 92 2.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30925 59c9103473647ed41b65f79dd6089a10 235 Hamap MF_01389 Urease accessory protein UreG [ureG]. 33 229 43.142 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 AFR_30925 59c9103473647ed41b65f79dd6089a10 235 SUPERFAMILY SSF52540 31 231 9.78E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30925 59c9103473647ed41b65f79dd6089a10 235 Gene3D G3DSA:3.40.50.300 34 230 5.2E-46 T 12-10-2018 AFR_30925 59c9103473647ed41b65f79dd6089a10 235 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 35 226 5.0E-84 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 AFR_30925 59c9103473647ed41b65f79dd6089a10 235 PIRSF PIRSF005624 27 234 9.2E-43 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 AFR_30925 59c9103473647ed41b65f79dd6089a10 235 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 37 204 9.8E-35 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFR_28415 6681f77ad88578c2f2643720b6badac6 281 SMART SM00849 9 222 2.1E-4 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_28415 6681f77ad88578c2f2643720b6badac6 281 SUPERFAMILY SSF56281 5 249 8.89E-24 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_28415 6681f77ad88578c2f2643720b6badac6 281 Gene3D G3DSA:3.60.15.10 1 258 5.4E-54 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_28415 6681f77ad88578c2f2643720b6badac6 281 Pfam PF12706 Beta-lactamase superfamily domain 44 223 9.8E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_31455 abc88c8910fbd2a4b537df10fdcf6415 264 SUPERFAMILY SSF51735 65 249 4.48E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_31455 abc88c8910fbd2a4b537df10fdcf6415 264 Gene3D G3DSA:3.40.50.720 67 255 4.8E-34 T 12-10-2018 AFR_31455 abc88c8910fbd2a4b537df10fdcf6415 264 Pfam PF13460 NAD(P)H-binding 72 245 1.5E-18 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_11400 ab6e3a3a67516501c06f080b43531ec4 331 Gene3D G3DSA:1.10.3720.10 39 315 3.1E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11400 ab6e3a3a67516501c06f080b43531ec4 331 SUPERFAMILY SSF161098 44 318 9.42E-49 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11400 ab6e3a3a67516501c06f080b43531ec4 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 317 5.6E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_02110 c1d2591c324ed3fd35de1b79477a48d2 221 SUPERFAMILY SSF53167 12 207 4.11E-23 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFR_02110 c1d2591c324ed3fd35de1b79477a48d2 221 Pfam PF01048 Phosphorylase superfamily 37 219 5.7E-7 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFR_02110 c1d2591c324ed3fd35de1b79477a48d2 221 Hamap MF_00991 Futalosine hydrolase [mqnB]. 11 221 20.868 T 12-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 AFR_02110 c1d2591c324ed3fd35de1b79477a48d2 221 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 11 218 5.0E-60 T 12-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 AFR_02110 c1d2591c324ed3fd35de1b79477a48d2 221 Gene3D G3DSA:3.40.50.1580 6 220 5.2E-26 T 12-10-2018 AFR_32270 f9f7b0251ab9e045a3e4f2042aa59dac 157 Pfam PF01661 Macro domain 24 138 3.7E-5 T 12-10-2018 IPR002589 Macro domain AFR_32270 f9f7b0251ab9e045a3e4f2042aa59dac 157 SMART SM00506 3 141 5.2E-16 T 12-10-2018 IPR002589 Macro domain AFR_32270 f9f7b0251ab9e045a3e4f2042aa59dac 157 SUPERFAMILY SSF52949 4 156 2.55E-42 T 12-10-2018 AFR_32270 f9f7b0251ab9e045a3e4f2042aa59dac 157 Gene3D G3DSA:3.40.220.10 4 157 6.7E-51 T 12-10-2018 AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 Gene3D G3DSA:3.40.50.720 2 277 1.7E-71 T 12-10-2018 AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 SUPERFAMILY SSF51735 4 246 1.88E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 8.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 Pfam PF00106 short chain dehydrogenase 7 188 4.6E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11085 c96045f5d2f17c20e7179fd47d53f8f8 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_31650 1fe28752772395ed4ef41b81e540512c 789 SUPERFAMILY SSF141868 536 781 2.09E-81 T 12-10-2018 IPR035919 EAL domain superfamily AFR_31650 1fe28752772395ed4ef41b81e540512c 789 Gene3D G3DSA:3.30.70.270 358 532 2.6E-54 T 12-10-2018 AFR_31650 1fe28752772395ed4ef41b81e540512c 789 SMART SM00052 529 776 1.8E-110 T 12-10-2018 IPR001633 EAL domain AFR_31650 1fe28752772395ed4ef41b81e540512c 789 Pfam PF00990 Diguanylate cyclase, GGDEF domain 361 514 7.0E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_31650 1fe28752772395ed4ef41b81e540512c 789 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 357 518 1.6E-38 T 12-10-2018 IPR000160 GGDEF domain AFR_31650 1fe28752772395ed4ef41b81e540512c 789 Pfam PF00563 EAL domain 536 771 3.7E-68 T 12-10-2018 IPR001633 EAL domain AFR_31650 1fe28752772395ed4ef41b81e540512c 789 Gene3D G3DSA:3.20.20.450 533 786 1.4E-90 T 12-10-2018 IPR035919 EAL domain superfamily AFR_31650 1fe28752772395ed4ef41b81e540512c 789 SUPERFAMILY SSF55073 366 520 1.88E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_31650 1fe28752772395ed4ef41b81e540512c 789 SMART SM00267 350 519 5.4E-59 T 12-10-2018 IPR000160 GGDEF domain AFR_31890 f1dd2ca32e789186e91aebc3ba6f021c 168 Gene3D G3DSA:2.40.128.110 9 167 3.5E-29 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily AFR_31890 f1dd2ca32e789186e91aebc3ba6f021c 168 SMART SM00867 9 166 5.7E-19 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFR_31890 f1dd2ca32e789186e91aebc3ba6f021c 168 Pfam PF04264 YceI-like domain 10 164 3.0E-25 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFR_31890 f1dd2ca32e789186e91aebc3ba6f021c 168 SUPERFAMILY SSF101874 7 165 2.62E-27 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily AFR_12015 5111d99f7b57d39fac492199c04aa894 507 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 323 506 4.4E-36 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_12015 5111d99f7b57d39fac492199c04aa894 507 Gene3D G3DSA:3.30.450.20 130 200 2.6E-9 T 12-10-2018 AFR_12015 5111d99f7b57d39fac492199c04aa894 507 Gene3D G3DSA:3.60.40.10 259 505 1.3E-42 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_12015 5111d99f7b57d39fac492199c04aa894 507 SMART SM00331 296 505 2.2E-16 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_12015 5111d99f7b57d39fac492199c04aa894 507 SUPERFAMILY SSF81606 310 502 7.85E-7 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_23405 6032a00055b96a50691ee3b76198e3b8 397 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 345 356 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site AFR_23405 6032a00055b96a50691ee3b76198e3b8 397 Gene3D G3DSA:2.40.10.10 280 382 8.7E-22 T 12-10-2018 AFR_23405 6032a00055b96a50691ee3b76198e3b8 397 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 235 240 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_23405 6032a00055b96a50691ee3b76198e3b8 397 Gene3D G3DSA:2.40.10.10 208 393 8.7E-22 T 12-10-2018 AFR_23405 6032a00055b96a50691ee3b76198e3b8 397 SUPERFAMILY SSF50494 217 374 4.8E-15 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_16890 a9a0648b236b3d3994e12954bf62636e 120 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 3 119 3.5E-33 T 12-10-2018 IPR018699 Protein of unknown function DUF2203 AFR_16890 a9a0648b236b3d3994e12954bf62636e 120 PIRSF PIRSF016498 1 120 7.4E-21 T 12-10-2018 IPR018699 Protein of unknown function DUF2203 AFR_30785 ae6ac62817967fef275982556d5052b9 248 Gene3D G3DSA:3.40.50.300 2 247 1.5E-54 T 12-10-2018 AFR_30785 ae6ac62817967fef275982556d5052b9 248 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_30785 ae6ac62817967fef275982556d5052b9 248 Pfam PF00005 ABC transporter 21 160 1.5E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_30785 ae6ac62817967fef275982556d5052b9 248 SMART SM00382 30 208 1.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_30785 ae6ac62817967fef275982556d5052b9 248 SUPERFAMILY SSF52540 4 220 4.83E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13705 3e289badf12faf8758ca9948a48c6eb6 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 67 4.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13705 3e289badf12faf8758ca9948a48c6eb6 234 SUPERFAMILY SSF46689 10 85 2.15E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13705 3e289badf12faf8758ca9948a48c6eb6 234 Gene3D G3DSA:1.10.357.10 3 227 4.1E-48 T 12-10-2018 AFR_13705 3e289badf12faf8758ca9948a48c6eb6 234 SUPERFAMILY SSF48498 94 224 1.67E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 Pfam PF06441 Epoxide hydrolase N terminus 1 63 1.8E-19 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 PIRSF PIRSF001112 1 335 3.6E-100 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 SUPERFAMILY SSF53474 5 332 5.35E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 PRINTS PR00412 Epoxide hydrolase signature 128 141 2.9E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 PRINTS PR00412 Epoxide hydrolase signature 54 72 2.9E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 PRINTS PR00412 Epoxide hydrolase signature 83 98 2.9E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 PRINTS PR00412 Epoxide hydrolase signature 142 155 2.9E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 PRINTS PR00412 Epoxide hydrolase signature 307 329 2.9E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_15025 ef0cf0d8e875518cffba478993b2bfa6 336 Gene3D G3DSA:3.40.50.1820 1 335 4.4E-110 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32785 270520a4e04a31a865721bf9e1f6d6d6 154 SUPERFAMILY SSF52218 4 132 2.58E-23 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_32785 270520a4e04a31a865721bf9e1f6d6d6 154 Pfam PF03358 NADPH-dependent FMN reductase 4 130 1.5E-22 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_32785 270520a4e04a31a865721bf9e1f6d6d6 154 Gene3D G3DSA:3.40.50.360 2 153 9.1E-29 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_31600 766699dc60ff6d2627b087c7df05bf9d 87 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 22 83 2.8E-9 T 12-10-2018 IPR001607 Zinc finger, UBP-type GO:0008270 AFR_31600 766699dc60ff6d2627b087c7df05bf9d 87 SUPERFAMILY SSF57850 2 84 5.89E-22 T 12-10-2018 AFR_31600 766699dc60ff6d2627b087c7df05bf9d 87 Gene3D G3DSA:3.30.40.10 1 86 5.4E-24 T 12-10-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type AFR_29710 6cfb44066731eba87a485f9c81659467 71 Pfam PF10049 Protein of unknown function (DUF2283) 3 56 1.8E-12 T 12-10-2018 IPR019270 Protein of unknown function DUF2283 AFR_35100 44795604fbba10fbd39185ed05e47c70 332 SUPERFAMILY SSF50129 1 147 6.09E-38 T 12-10-2018 IPR011032 GroES-like superfamily AFR_35100 44795604fbba10fbd39185ed05e47c70 332 Gene3D G3DSA:3.90.180.10 9 327 5.1E-97 T 12-10-2018 AFR_35100 44795604fbba10fbd39185ed05e47c70 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 94 1.9E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_35100 44795604fbba10fbd39185ed05e47c70 332 Pfam PF13602 Zinc-binding dehydrogenase 208 328 3.9E-26 T 12-10-2018 AFR_35100 44795604fbba10fbd39185ed05e47c70 332 SMART SM00829 10 328 2.7E-21 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_35100 44795604fbba10fbd39185ed05e47c70 332 Gene3D G3DSA:3.40.50.720 134 279 5.1E-97 T 12-10-2018 AFR_35100 44795604fbba10fbd39185ed05e47c70 332 SUPERFAMILY SSF51735 123 265 2.32E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_31900 deb782153fdfb0aa6da65191650b75cd 214 SUPERFAMILY SSF54001 14 200 1.96E-26 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_31900 deb782153fdfb0aa6da65191650b75cd 214 Gene3D G3DSA:3.90.1720.10 3 197 9.7E-9 T 12-10-2018 AFR_22065 608121f5cdf90507232baf2ce41f9540 306 Pfam PF00005 ABC transporter 17 160 1.9E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_22065 608121f5cdf90507232baf2ce41f9540 306 Gene3D G3DSA:3.40.50.300 1 224 2.4E-64 T 12-10-2018 AFR_22065 608121f5cdf90507232baf2ce41f9540 306 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_22065 608121f5cdf90507232baf2ce41f9540 306 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 9 300 3.3E-95 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFR_22065 608121f5cdf90507232baf2ce41f9540 306 SMART SM00382 26 209 3.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22065 608121f5cdf90507232baf2ce41f9540 306 SUPERFAMILY SSF52540 3 220 4.58E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28600 0118028ff5babd95bc3afd4cb7fd15e5 226 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_28600 0118028ff5babd95bc3afd4cb7fd15e5 226 Gene3D G3DSA:3.40.50.300 2 224 2.0E-67 T 12-10-2018 AFR_28600 0118028ff5babd95bc3afd4cb7fd15e5 226 SUPERFAMILY SSF52540 6 222 2.08E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28600 0118028ff5babd95bc3afd4cb7fd15e5 226 SMART SM00382 31 218 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_28600 0118028ff5babd95bc3afd4cb7fd15e5 226 Pfam PF00005 ABC transporter 22 170 1.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_11740 e356f929d3e682544b602f4701045454 132 Gene3D G3DSA:1.10.10.10 39 119 2.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11740 e356f929d3e682544b602f4701045454 132 SUPERFAMILY SSF46785 42 119 4.35E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11740 e356f929d3e682544b602f4701045454 132 Pfam PF11625 Protein of unknown function (DUF3253) 43 118 3.7E-25 T 12-10-2018 IPR021660 Protein of unknown function DUF3253 AFR_27785 f79e0f75b43ce9821a004c905418b329 428 Gene3D G3DSA:3.40.640.10 59 321 2.6E-168 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_27785 f79e0f75b43ce9821a004c905418b329 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27785 f79e0f75b43ce9821a004c905418b329 428 PIRSF PIRSF000521 1 130 1.1E-4 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27785 f79e0f75b43ce9821a004c905418b329 428 PIRSF PIRSF000521 123 425 4.5E-36 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27785 f79e0f75b43ce9821a004c905418b329 428 SUPERFAMILY SSF53383 18 422 1.87E-123 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_27785 f79e0f75b43ce9821a004c905418b329 428 Pfam PF00202 Aminotransferase class-III 21 420 3.8E-127 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_27785 f79e0f75b43ce9821a004c905418b329 428 Gene3D G3DSA:3.90.1150.10 3 418 2.6E-168 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_27785 f79e0f75b43ce9821a004c905418b329 428 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 422 2.5E-177 T 12-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 AFR_32310 dfa6ff6dcd553947c7d41d58ad64fab5 192 SUPERFAMILY SSF46689 3 78 8.98E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_32310 dfa6ff6dcd553947c7d41d58ad64fab5 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 6.3E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32310 dfa6ff6dcd553947c7d41d58ad64fab5 192 Gene3D G3DSA:1.10.357.10 51 191 4.5E-14 T 12-10-2018 AFR_32310 dfa6ff6dcd553947c7d41d58ad64fab5 192 SUPERFAMILY SSF48498 73 190 1.22E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_32310 dfa6ff6dcd553947c7d41d58ad64fab5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32310 dfa6ff6dcd553947c7d41d58ad64fab5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_32310 dfa6ff6dcd553947c7d41d58ad64fab5 192 Gene3D G3DSA:1.10.10.60 2 50 3.3E-13 T 12-10-2018 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 Pfam PF00089 Trypsin 28 247 1.8E-20 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 119 133 3.0E-8 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 62 77 3.0E-8 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 197 209 3.0E-8 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 72 77 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 SUPERFAMILY SSF50494 16 252 1.12E-31 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 Gene3D G3DSA:2.40.10.10 120 253 3.9E-8 T 12-10-2018 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 Gene3D G3DSA:2.40.10.10 27 119 4.9E-11 T 12-10-2018 AFR_28510 7e474b30b5dc1abff6bd1ce9c5e368f9 293 SMART SM00020 26 247 2.1E-8 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_00050 4036cb41b7b6fd2062f4bbb70eaab09a 295 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 170 293 2.1E-41 T 12-10-2018 IPR021949 Domain of unknown function DUF3566. transmembrane AFR_31535 ba27099165c94ec098cc979012a37641 286 PIRSF PIRSF000241 2 282 1.4E-87 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 Gene3D G3DSA:3.10.270.10 1 286 4.8E-98 T 12-10-2018 AFR_31535 ba27099165c94ec098cc979012a37641 286 SUPERFAMILY SSF55620 3 124 4.78E-41 T 12-10-2018 AFR_31535 ba27099165c94ec098cc979012a37641 286 PRINTS PR00093 Uricase signature 50 64 2.0E-20 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 PRINTS PR00093 Uricase signature 11 22 2.0E-20 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 PRINTS PR00093 Uricase signature 142 158 2.0E-20 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 PRINTS PR00093 Uricase signature 158 170 2.0E-20 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 PRINTS PR00093 Uricase signature 86 99 2.0E-20 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 172 274 2.0E-28 T 12-10-2018 AFR_31535 ba27099165c94ec098cc979012a37641 286 SUPERFAMILY SSF55620 133 284 1.95E-51 T 12-10-2018 AFR_31535 ba27099165c94ec098cc979012a37641 286 TIGRFAM TIGR03383 urate_oxi: urate oxidase 5 274 1.6E-95 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 Pfam PF01014 Uricase 9 123 6.1E-16 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_31535 ba27099165c94ec098cc979012a37641 286 Pfam PF01014 Uricase 136 269 4.9E-26 T 12-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 AFR_05085 747e2a98b7a8f6ecc792e68187b96bc3 134 Pfam PF02310 B12 binding domain 5 119 6.5E-25 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_05085 747e2a98b7a8f6ecc792e68187b96bc3 134 Gene3D G3DSA:3.40.50.280 1 133 2.9E-59 T 12-10-2018 AFR_05085 747e2a98b7a8f6ecc792e68187b96bc3 134 SUPERFAMILY SSF52242 3 129 2.62E-49 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_05085 747e2a98b7a8f6ecc792e68187b96bc3 134 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 4 130 4.7E-49 T 12-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_11140 a1ec8407e50bcbbf32d70a81d7145eb2 269 SUPERFAMILY SSF55315 6 103 5.18E-14 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFR_11140 a1ec8407e50bcbbf32d70a81d7145eb2 269 SUPERFAMILY SSF75217 96 265 1.11E-35 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFR_11140 a1ec8407e50bcbbf32d70a81d7145eb2 269 Pfam PF00588 SpoU rRNA Methylase family 119 260 7.7E-28 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFR_11140 a1ec8407e50bcbbf32d70a81d7145eb2 269 Gene3D G3DSA:3.40.1280.10 107 267 5.6E-44 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFR_40770 29d4a5d4729b59406503951ca1cf6470 361 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 62 353 2.0E-84 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AFR_40770 29d4a5d4729b59406503951ca1cf6470 361 SUPERFAMILY SSF161098 76 346 3.79E-29 T 12-10-2018 IPR035906 MetI-like superfamily AFR_40770 29d4a5d4729b59406503951ca1cf6470 361 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 349 2.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_40770 29d4a5d4729b59406503951ca1cf6470 361 Gene3D G3DSA:1.10.3720.10 116 355 1.3E-30 T 12-10-2018 IPR035906 MetI-like superfamily AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 75 89 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 SUPERFAMILY SSF54506 141 278 8.44E-26 T 12-10-2018 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 Gene3D G3DSA:3.10.310.10 143 275 2.1E-80 T 12-10-2018 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 Pfam PF01678 Diaminopimelate epimerase 6 124 1.8E-29 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 Pfam PF01678 Diaminopimelate epimerase 152 277 1.3E-13 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 279 28.021 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 277 3.1E-57 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 Gene3D G3DSA:3.10.310.10 6 142 2.1E-80 T 12-10-2018 AFR_35550 3551571e07b6dc322de7d6a32bda6ab1 283 SUPERFAMILY SSF54506 6 136 5.76E-34 T 12-10-2018 AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 Pfam PF13185 GAF domain 24 162 1.8E-16 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 SUPERFAMILY SSF55781 25 170 2.39E-22 T 12-10-2018 AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 Pfam PF03861 ANTAR domain 176 229 3.6E-23 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 PIRSF PIRSF036625 1 236 8.9E-61 T 12-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 Gene3D G3DSA:1.10.10.10 176 236 7.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 Gene3D G3DSA:3.30.450.40 9 170 1.2E-23 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 SMART SM01012 174 229 2.5E-25 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_16630 9c13c558a561c0d5f45ca0b3ed1831a3 237 SMART SM00065 25 172 3.7E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_02390 6175ff7ee2cfbf4a161c5a8bcb3fa3c8 157 Gene3D G3DSA:2.60.120.10 7 143 6.7E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_02390 6175ff7ee2cfbf4a161c5a8bcb3fa3c8 157 Pfam PF05995 Cysteine dioxygenase type I 15 138 1.2E-26 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 AFR_02390 6175ff7ee2cfbf4a161c5a8bcb3fa3c8 157 SUPERFAMILY SSF51182 12 140 4.46E-30 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_14720 07b545428694e07a9176c1737e8d8b31 134 Pfam PF01042 Endoribonuclease L-PSP 18 133 1.4E-22 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_14720 07b545428694e07a9176c1737e8d8b31 134 SUPERFAMILY SSF55298 10 134 8.17E-26 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_14720 07b545428694e07a9176c1737e8d8b31 134 Gene3D G3DSA:3.30.1330.40 6 134 3.3E-26 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_24900 d66231eb24dbf3a424a40205f4fe5b2b 143 Pfam PF00932 Lamin Tail Domain 27 135 3.3E-19 T 12-10-2018 IPR001322 Lamin tail domain AFR_24900 d66231eb24dbf3a424a40205f4fe5b2b 143 SUPERFAMILY SSF74853 44 135 1.57E-14 T 12-10-2018 IPR036415 Lamin tail domain superfamily AFR_08380 7a1449ca6dda44ad5533898a3749bf28 172 SUPERFAMILY SSF53597 4 171 6.94E-22 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_08380 7a1449ca6dda44ad5533898a3749bf28 172 Pfam PF01872 RibD C-terminal domain 4 157 2.4E-13 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_08380 7a1449ca6dda44ad5533898a3749bf28 172 Gene3D G3DSA:3.40.430.10 1 169 1.5E-33 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_05220 05e4ab672c8230450f4f7c93c4cc7ca2 304 SUPERFAMILY SSF52540 9 213 6.43E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05220 05e4ab672c8230450f4f7c93c4cc7ca2 304 SMART SM00382 28 229 9.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_05220 05e4ab672c8230450f4f7c93c4cc7ca2 304 Gene3D G3DSA:3.40.50.300 2 236 2.7E-59 T 12-10-2018 AFR_05220 05e4ab672c8230450f4f7c93c4cc7ca2 304 Pfam PF00005 ABC transporter 20 163 3.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_15975 fe539799d42023b57af78ddbdaeba5e5 348 SUPERFAMILY SSF53448 1 214 4.69E-45 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_15975 fe539799d42023b57af78ddbdaeba5e5 348 Pfam PF00535 Glycosyl transferase family 2 1 128 2.0E-29 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_15975 fe539799d42023b57af78ddbdaeba5e5 348 Gene3D G3DSA:3.90.550.10 1 235 7.9E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_28565 3e4895ddc765adaccd174aa8d7fab5ff 211 Gene3D G3DSA:1.10.357.10 82 211 3.2E-8 T 12-10-2018 AFR_28565 3e4895ddc765adaccd174aa8d7fab5ff 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28565 3e4895ddc765adaccd174aa8d7fab5ff 211 Gene3D G3DSA:1.10.10.60 2 66 4.7E-13 T 12-10-2018 AFR_28565 3e4895ddc765adaccd174aa8d7fab5ff 211 SUPERFAMILY SSF48498 97 203 4.07E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_28565 3e4895ddc765adaccd174aa8d7fab5ff 211 SUPERFAMILY SSF46689 9 73 1.64E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37480 4fd0de85c2de3947cdefc29bc15e697d 349 Gene3D G3DSA:3.40.50.1100 58 154 2.9E-122 T 12-10-2018 AFR_37480 4fd0de85c2de3947cdefc29bc15e697d 349 Gene3D G3DSA:3.40.50.1100 9 322 2.9E-122 T 12-10-2018 AFR_37480 4fd0de85c2de3947cdefc29bc15e697d 349 PIRSF PIRSF038945 1 348 1.1E-163 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 AFR_37480 4fd0de85c2de3947cdefc29bc15e697d 349 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 316 1.1E-70 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_37480 4fd0de85c2de3947cdefc29bc15e697d 349 SUPERFAMILY SSF53686 3 332 6.68E-105 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_37480 4fd0de85c2de3947cdefc29bc15e697d 349 TIGRFAM TIGR00260 thrC: threonine synthase 6 323 1.3E-95 T 12-10-2018 IPR004450 Threonine synthase-like AFR_37480 4fd0de85c2de3947cdefc29bc15e697d 349 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFR_39940 e6e5a3ccb3f5e3aaeae482e8f1061624 144 Pfam PF01475 Ferric uptake regulator family 11 126 9.4E-23 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFR_39940 e6e5a3ccb3f5e3aaeae482e8f1061624 144 Gene3D G3DSA:3.30.1490.190 84 140 6.7E-15 T 12-10-2018 AFR_39940 e6e5a3ccb3f5e3aaeae482e8f1061624 144 SUPERFAMILY SSF46785 5 132 6.01E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_39940 e6e5a3ccb3f5e3aaeae482e8f1061624 144 Gene3D G3DSA:1.10.10.10 2 81 2.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 190 0.0017 T 12-10-2018 AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 246 7.7E-53 T 12-10-2018 AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 SUPERFAMILY SSF51735 7 247 4.78E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_30430 dd0eb1b86b308a5f843eb010437e08df 248 Gene3D G3DSA:3.40.50.720 4 247 3.1E-69 T 12-10-2018 AFR_07815 9c60c7381fe32ac91b30055b203750ae 547 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 405 516 6.3E-8 T 12-10-2018 IPR000014 PAS domain AFR_07815 9c60c7381fe32ac91b30055b203750ae 547 Gene3D G3DSA:3.30.450.20 402 518 1.5E-13 T 12-10-2018 AFR_07815 9c60c7381fe32ac91b30055b203750ae 547 Pfam PF00989 PAS fold 410 513 3.4E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 AFR_07815 9c60c7381fe32ac91b30055b203750ae 547 SUPERFAMILY SSF55785 404 514 4.34E-13 T 12-10-2018 IPR035965 PAS domain superfamily AFR_07815 9c60c7381fe32ac91b30055b203750ae 547 SMART SM00091 408 473 7.4E-9 T 12-10-2018 IPR000014 PAS domain AFR_30480 7a6cd0c7362e914d5a6df00a3480cf62 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 2 86 2.3E-7 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 AFR_30480 7a6cd0c7362e914d5a6df00a3480cf62 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.55 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFR_30480 7a6cd0c7362e914d5a6df00a3480cf62 87 Gene3D G3DSA:1.10.287.1080 1 87 5.8E-21 T 12-10-2018 AFR_30480 7a6cd0c7362e914d5a6df00a3480cf62 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 4.7E-20 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFR_30480 7a6cd0c7362e914d5a6df00a3480cf62 87 SUPERFAMILY SSF101386 2 87 1.96E-20 T 12-10-2018 AFR_25530 45c58e21ab29461b19a0c2814f441972 509 SUPERFAMILY SSF52540 249 496 1.95E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25530 45c58e21ab29461b19a0c2814f441972 509 Gene3D G3DSA:3.40.50.300 259 507 2.2E-38 T 12-10-2018 AFR_25530 45c58e21ab29461b19a0c2814f441972 509 Gene3D G3DSA:3.40.50.300 2 243 5.8E-55 T 12-10-2018 AFR_25530 45c58e21ab29461b19a0c2814f441972 509 Pfam PF00005 ABC transporter 21 172 3.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_25530 45c58e21ab29461b19a0c2814f441972 509 SUPERFAMILY SSF52540 4 225 5.43E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25530 45c58e21ab29461b19a0c2814f441972 509 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_25530 45c58e21ab29461b19a0c2814f441972 509 SMART SM00382 289 484 1.7E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25530 45c58e21ab29461b19a0c2814f441972 509 SMART SM00382 30 220 4.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25530 45c58e21ab29461b19a0c2814f441972 509 Pfam PF00005 ABC transporter 281 436 9.6E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04515 f07fdece78fc634c5da154160b6dacb1 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 97 20.796 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFR_04515 f07fdece78fc634c5da154160b6dacb1 100 SUPERFAMILY SSF54189 5 97 2.73E-30 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04515 f07fdece78fc634c5da154160b6dacb1 100 Pfam PF00276 Ribosomal protein L23 9 93 8.9E-30 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFR_04515 f07fdece78fc634c5da154160b6dacb1 100 Gene3D G3DSA:3.30.70.330 7 97 9.6E-31 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFR_16455 d450bfe1581ee9d9d330536a2d03ad94 387 Pfam PF13229 Right handed beta helix region 155 306 3.5E-6 T 12-10-2018 IPR039448 Right handed beta helix domain AFR_16455 d450bfe1581ee9d9d330536a2d03ad94 387 Gene3D G3DSA:2.160.20.10 33 355 7.6E-10 T 12-10-2018 IPR012334 Pectin lyase fold AFR_16455 d450bfe1581ee9d9d330536a2d03ad94 387 SUPERFAMILY SSF51126 22 367 3.14E-15 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_20715 07b760a74ed4b827a3f763ddf9a979b8 331 Pfam PF13407 Periplasmic binding protein domain 54 297 4.6E-40 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_20715 07b760a74ed4b827a3f763ddf9a979b8 331 Gene3D G3DSA:3.40.50.2300 60 312 7.8E-85 T 12-10-2018 AFR_20715 07b760a74ed4b827a3f763ddf9a979b8 331 Gene3D G3DSA:3.40.50.2300 154 314 7.8E-85 T 12-10-2018 AFR_20715 07b760a74ed4b827a3f763ddf9a979b8 331 SUPERFAMILY SSF53822 48 320 1.45E-50 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_18975 4ae7af236de1fbe785207d608c204321 433 Gene3D G3DSA:1.20.1250.20 5 397 1.1E-33 T 12-10-2018 AFR_18975 4ae7af236de1fbe785207d608c204321 433 SUPERFAMILY SSF103473 9 399 7.98E-38 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_18975 4ae7af236de1fbe785207d608c204321 433 Pfam PF05977 Transmembrane secretion effector 7 404 4.7E-33 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_29740 3c72d4feaaeab0028115ca42bb3ff5dc 329 SUPERFAMILY SSF51735 115 290 6.12E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29740 3c72d4feaaeab0028115ca42bb3ff5dc 329 Gene3D G3DSA:3.90.180.10 9 320 4.6E-88 T 12-10-2018 AFR_29740 3c72d4feaaeab0028115ca42bb3ff5dc 329 SMART SM00829 10 322 1.4E-22 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_29740 3c72d4feaaeab0028115ca42bb3ff5dc 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFR_29740 3c72d4feaaeab0028115ca42bb3ff5dc 329 SUPERFAMILY SSF50129 1 150 6.85E-29 T 12-10-2018 IPR011032 GroES-like superfamily AFR_29740 3c72d4feaaeab0028115ca42bb3ff5dc 329 Gene3D G3DSA:3.40.50.720 125 269 4.6E-88 T 12-10-2018 AFR_29740 3c72d4feaaeab0028115ca42bb3ff5dc 329 Pfam PF00107 Zinc-binding dehydrogenase 152 280 1.5E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_10420 d97f4a3a9ff9dc62555c6db2376c9850 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 301 2.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_10420 d97f4a3a9ff9dc62555c6db2376c9850 333 Gene3D G3DSA:1.10.3720.10 65 305 1.9E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_10420 d97f4a3a9ff9dc62555c6db2376c9850 333 SUPERFAMILY SSF161098 71 294 2.35E-42 T 12-10-2018 IPR035906 MetI-like superfamily AFR_05300 cb6ac6bd4cfdc9f2e4b1ac54db084af3 316 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 138 214 1.8E-22 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFR_05300 cb6ac6bd4cfdc9f2e4b1ac54db084af3 316 SUPERFAMILY SSF101386 119 215 3.18E-18 T 12-10-2018 AFR_05300 cb6ac6bd4cfdc9f2e4b1ac54db084af3 316 Gene3D G3DSA:1.10.287.1080 114 239 6.3E-39 T 12-10-2018 AFR_16960 9214c23aa8e18c2d98802b49601ecc65 185 SUPERFAMILY SSF46894 79 171 2.78E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_16960 9214c23aa8e18c2d98802b49601ecc65 185 Pfam PF00486 Transcriptional regulatory protein, C terminal 96 170 1.2E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_16960 9214c23aa8e18c2d98802b49601ecc65 185 SMART SM00862 95 170 1.7E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_16960 9214c23aa8e18c2d98802b49601ecc65 185 Gene3D G3DSA:1.10.10.10 78 181 2.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05215 e64c5210dc63254f28305768f1a6d743 440 Pfam PF02156 Glycosyl hydrolase family 26 239 321 3.3E-8 T 12-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 AFR_05215 e64c5210dc63254f28305768f1a6d743 440 Gene3D G3DSA:3.20.20.80 133 425 2.9E-52 T 12-10-2018 AFR_05215 e64c5210dc63254f28305768f1a6d743 440 SUPERFAMILY SSF51445 196 406 1.7E-27 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_19490 d8baeca14dfc7dc759498f52126500f1 392 Gene3D G3DSA:3.30.70.1380 231 321 1.2E-13 T 12-10-2018 AFR_19490 d8baeca14dfc7dc759498f52126500f1 392 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 6 371 3.7E-89 T 12-10-2018 IPR002822 Nickel insertion protein AFR_19490 d8baeca14dfc7dc759498f52126500f1 392 Hamap MF_01074 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein [larC]. 2 381 34.123 T 12-10-2018 IPR002822 Nickel insertion protein AFR_19490 d8baeca14dfc7dc759498f52126500f1 392 Pfam PF01969 Protein of unknown function DUF111 6 371 1.1E-125 T 12-10-2018 IPR002822 Nickel insertion protein AFR_17835 cb2c0b29759cc9de8fdb66f4bf03d60e 557 SUPERFAMILY SSF53300 360 547 7.6E-17 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_17835 cb2c0b29759cc9de8fdb66f4bf03d60e 557 Gene3D G3DSA:3.40.50.410 361 550 4.8E-21 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_17835 cb2c0b29759cc9de8fdb66f4bf03d60e 557 Pfam PF13531 Bacterial extracellular solute-binding protein 23 290 2.4E-20 T 12-10-2018 AFR_17835 cb2c0b29759cc9de8fdb66f4bf03d60e 557 SMART SM00327 358 549 6.0E-12 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_17835 cb2c0b29759cc9de8fdb66f4bf03d60e 557 Pfam PF00092 von Willebrand factor type A domain 363 543 7.1E-10 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_35810 cb933f1373e665556651a683fa8b60b7 465 SUPERFAMILY SSF102114 133 371 2.49E-42 T 12-10-2018 AFR_35810 cb933f1373e665556651a683fa8b60b7 465 Gene3D G3DSA:3.80.30.20 147 380 5.8E-64 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFR_35810 cb933f1373e665556651a683fa8b60b7 465 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 153 173 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFR_35810 cb933f1373e665556651a683fa8b60b7 465 Gene3D G3DSA:3.40.50.12160 1 107 1.4E-23 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AFR_35810 cb933f1373e665556651a683fa8b60b7 465 Pfam PF04055 Radical SAM superfamily 156 325 2.0E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_35810 cb933f1373e665556651a683fa8b60b7 465 Gene3D G3DSA:2.40.50.140 382 450 4.6E-7 T 12-10-2018 AFR_35810 cb933f1373e665556651a683fa8b60b7 465 SMART SM00729 149 367 3.4E-39 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_35810 cb933f1373e665556651a683fa8b60b7 465 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 1 448 54.628 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AFR_35810 cb933f1373e665556651a683fa8b60b7 465 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 2 445 2.2E-107 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AFR_35810 cb933f1373e665556651a683fa8b60b7 465 Pfam PF00919 Uncharacterized protein family UPF0004 1 77 2.7E-19 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 SMART SM00829 18 321 1.6E-29 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 154 175 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 Pfam PF13602 Zinc-binding dehydrogenase 196 321 1.3E-25 T 12-10-2018 AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 Gene3D G3DSA:3.40.50.720 137 272 2.3E-98 T 12-10-2018 AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 SUPERFAMILY SSF50129 5 159 7.46E-42 T 12-10-2018 IPR011032 GroES-like superfamily AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 SUPERFAMILY SSF51735 127 251 4.41E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 Gene3D G3DSA:3.90.180.10 17 320 2.3E-98 T 12-10-2018 AFR_13015 6e59f5ebd90b73b82b6437a4136b18fb 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 102 5.3E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_15745 f2a880b193c0a4593f415a677dbf7ff1 307 SUPERFAMILY SSF51556 18 304 1.05E-23 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_15745 f2a880b193c0a4593f415a677dbf7ff1 307 Gene3D G3DSA:3.20.20.140 160 304 1.6E-11 T 12-10-2018 AFR_13575 8162da4273ff22e83d3d755392140fcb 302 SUPERFAMILY SSF54373 160 246 2.75E-7 T 12-10-2018 AFR_13575 8162da4273ff22e83d3d755392140fcb 302 SUPERFAMILY SSF51905 41 302 2.33E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13575 8162da4273ff22e83d3d755392140fcb 302 Pfam PF01266 FAD dependent oxidoreductase 17 284 1.3E-36 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_13575 8162da4273ff22e83d3d755392140fcb 302 Gene3D G3DSA:3.50.50.60 85 285 1.0E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13575 8162da4273ff22e83d3d755392140fcb 302 Gene3D G3DSA:3.30.9.10 28 246 1.0E-38 T 12-10-2018 AFR_13680 7c1578128677df3337d669068fdafac9 391 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.2E-9 T 12-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated AFR_13680 7c1578128677df3337d669068fdafac9 391 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_13680 7c1578128677df3337d669068fdafac9 391 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 150 6.8E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_13680 7c1578128677df3337d669068fdafac9 391 Pfam PF00107 Zinc-binding dehydrogenase 198 267 2.6E-10 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_13680 7c1578128677df3337d669068fdafac9 391 Gene3D G3DSA:3.40.50.720 179 342 1.9E-127 T 12-10-2018 AFR_13680 7c1578128677df3337d669068fdafac9 391 SUPERFAMILY SSF51735 165 353 1.01E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13680 7c1578128677df3337d669068fdafac9 391 Gene3D G3DSA:3.90.180.10 8 377 1.9E-127 T 12-10-2018 AFR_13680 7c1578128677df3337d669068fdafac9 391 SUPERFAMILY SSF50129 1 206 1.92E-55 T 12-10-2018 IPR011032 GroES-like superfamily AFR_17550 989a82b05350fdbfbc15b1645aa674c9 534 SUPERFAMILY SSF53474 93 480 1.27E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_17550 989a82b05350fdbfbc15b1645aa674c9 534 Pfam PF00561 alpha/beta hydrolase fold 93 466 6.4E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_26115 7feac846c57133bff789327a0278186e 413 Gene3D G3DSA:3.20.20.120 128 369 1.4E-175 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_26115 7feac846c57133bff789327a0278186e 413 Pfam PF13378 Enolase C-terminal domain-like 165 376 1.6E-48 T 12-10-2018 IPR029065 Enolase C-terminal domain-like AFR_26115 7feac846c57133bff789327a0278186e 413 SUPERFAMILY SSF51604 128 385 5.24E-71 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFR_26115 7feac846c57133bff789327a0278186e 413 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 27 128 1.6E-4 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFR_26115 7feac846c57133bff789327a0278186e 413 SMART SM00922 162 256 1.8E-19 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFR_26115 7feac846c57133bff789327a0278186e 413 SUPERFAMILY SSF54826 2 128 1.08E-23 T 12-10-2018 AFR_26115 7feac846c57133bff789327a0278186e 413 Gene3D G3DSA:3.30.390.10 1 406 1.4E-175 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFR_16700 35d14314f7d927f7c6bdb2f4f9b59ed8 191 SUPERFAMILY SSF52540 3 118 1.96E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16700 35d14314f7d927f7c6bdb2f4f9b59ed8 191 Pfam PF13521 AAA domain 3 166 4.9E-26 T 12-10-2018 IPR038727 NadR/Ttd14, AAA domain AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 Gene3D G3DSA:2.30.30.40 43 113 2.9E-6 T 12-10-2018 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 Gene3D G3DSA:4.10.80.30 290 316 1.0E-41 T 12-10-2018 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 Gene3D G3DSA:1.10.530.10 233 383 1.0E-41 T 12-10-2018 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 SMART SM00287 141 212 0.079 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 SMART SM00287 42 114 0.33 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 PRINTS PR01002 Flagellar protein FlgJ signature 252 270 9.3E-7 T 12-10-2018 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 PRINTS PR01002 Flagellar protein FlgJ signature 360 378 9.3E-7 T 12-10-2018 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 PRINTS PR01002 Flagellar protein FlgJ signature 317 338 9.3E-7 T 12-10-2018 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 SMART SM00047 223 383 8.4E-29 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 Gene3D G3DSA:2.30.30.40 140 208 2.4E-6 T 12-10-2018 AFR_27035 7ba97bee76048044683ba73eb186d7f4 386 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 241 378 5.6E-23 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 SUPERFAMILY SSF55781 206 371 3.75E-11 T 12-10-2018 AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 Pfam PF13581 Histidine kinase-like ATPase domain 459 529 3.3E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 Gene3D G3DSA:3.30.565.10 425 552 1.3E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 Gene3D G3DSA:3.30.450.40 52 202 2.4E-54 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 Pfam PF13185 GAF domain 55 194 1.6E-16 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 Pfam PF07730 Histidine kinase 362 425 7.9E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 SMART SM00065 56 203 2.0E-21 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 SUPERFAMILY SSF55781 38 220 3.05E-38 T 12-10-2018 AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 Gene3D G3DSA:3.30.450.40 225 361 4.8E-12 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 SUPERFAMILY SSF55874 460 552 4.98E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_22190 a71010a8d6edcc82a37ef3dbdc40c70b 554 SMART SM00387 463 554 1.0E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_23070 e22cdb7426dce317a4069b0e6e351439 262 SUPERFAMILY SSF89550 3 250 6.54E-22 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFR_23070 e22cdb7426dce317a4069b0e6e351439 262 Gene3D G3DSA:3.20.20.140 1 251 4.6E-43 T 12-10-2018 AFR_09375 07f4b071bf2e4f9629ba4cd048a8fb3c 170 SUPERFAMILY SSF52540 5 128 1.68E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09375 07f4b071bf2e4f9629ba4cd048a8fb3c 170 Gene3D G3DSA:3.40.50.300 1 166 6.3E-24 T 12-10-2018 AFR_09375 07f4b071bf2e4f9629ba4cd048a8fb3c 170 Pfam PF13671 AAA domain 3 120 1.3E-17 T 12-10-2018 AFR_06390 7905bb76dd7f6ccd2892b73d3cd8b0ce 189 SMART SM00418 11 90 0.0021 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_06390 7905bb76dd7f6ccd2892b73d3cd8b0ce 189 Gene3D G3DSA:1.20.1270.400 89 177 1.5E-29 T 12-10-2018 AFR_06390 7905bb76dd7f6ccd2892b73d3cd8b0ce 189 Pfam PF12840 Helix-turn-helix domain 7 66 2.7E-10 T 12-10-2018 AFR_06390 7905bb76dd7f6ccd2892b73d3cd8b0ce 189 Gene3D G3DSA:1.10.10.10 2 82 6.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06390 7905bb76dd7f6ccd2892b73d3cd8b0ce 189 SUPERFAMILY SSF46785 10 166 2.5E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_34545 83204035f018fbd29deb656389224a61 320 SUPERFAMILY SSF46894 258 318 2.48E-9 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_34545 83204035f018fbd29deb656389224a61 320 Gene3D G3DSA:1.10.10.10 215 319 1.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34545 83204035f018fbd29deb656389224a61 320 SMART SM00421 255 312 8.6E-4 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_13595 a9b9377aef40606873141fa31be3920a 191 SUPERFAMILY SSF48498 77 183 2.14E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13595 a9b9377aef40606873141fa31be3920a 191 Pfam PF16859 Bacterial transcriptional repressor C-terminal 82 182 9.7E-11 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_13595 a9b9377aef40606873141fa31be3920a 191 Gene3D G3DSA:1.10.357.10 55 185 1.3E-12 T 12-10-2018 AFR_13595 a9b9377aef40606873141fa31be3920a 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13595 a9b9377aef40606873141fa31be3920a 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13595 a9b9377aef40606873141fa31be3920a 191 SUPERFAMILY SSF46689 7 66 1.75E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13595 a9b9377aef40606873141fa31be3920a 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 5.0E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13595 a9b9377aef40606873141fa31be3920a 191 Gene3D G3DSA:1.10.10.60 6 54 6.5E-18 T 12-10-2018 AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 Pfam PF13527 Acetyltransferase (GNAT) domain 9 133 2.3E-30 T 12-10-2018 AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 Pfam PF13530 Sterol carrier protein domain 183 407 1.1E-49 T 12-10-2018 IPR025559 Enhanced intracellular survival protein domain AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 Gene3D G3DSA:3.40.630.30 136 296 5.0E-35 T 12-10-2018 AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 Hamap MF_01812 N-acetyltransferase Eis [eis]. 5 413 33.659 T 12-10-2018 IPR022902 N-acetyltransferase Eis AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 Gene3D G3DSA:3.30.1050.10 305 402 2.7E-31 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 SUPERFAMILY SSF55718 307 409 7.85E-22 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 Gene3D G3DSA:3.40.630.30 4 135 1.7E-34 T 12-10-2018 AFR_07500 6ac36b72afb8e6c6516cf009dd8ae112 413 SUPERFAMILY SSF55729 8 306 1.14E-58 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_17700 7ef78947c0769daef58b1c24981c3b5c 279 Gene3D G3DSA:3.60.70.12 1 279 1.4E-71 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFR_17700 7ef78947c0769daef58b1c24981c3b5c 279 Pfam PF03576 Peptidase family S58 1 279 2.1E-35 T 12-10-2018 IPR005321 Peptidase S58, DmpA AFR_17700 7ef78947c0769daef58b1c24981c3b5c 279 SUPERFAMILY SSF56266 1 279 6.8E-41 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFR_10725 983a6c714e4d24828b2cc234406fb2e9 572 Gene3D G3DSA:3.50.30.80 372 526 2.0E-47 T 12-10-2018 AFR_10725 983a6c714e4d24828b2cc234406fb2e9 572 Pfam PF00920 Dehydratase family 37 554 2.3E-170 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_10725 983a6c714e4d24828b2cc234406fb2e9 572 SUPERFAMILY SSF52016 372 559 5.34E-54 T 12-10-2018 AFR_10725 983a6c714e4d24828b2cc234406fb2e9 572 SUPERFAMILY SSF143975 3 370 7.45E-113 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFR_17860 f751f5f82e6a73a01bd5034858ca7359 296 SUPERFAMILY SSF46785 1 109 1.12E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17860 f751f5f82e6a73a01bd5034858ca7359 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_17860 f751f5f82e6a73a01bd5034858ca7359 296 Gene3D G3DSA:3.40.190.10 165 267 4.6E-36 T 12-10-2018 AFR_17860 f751f5f82e6a73a01bd5034858ca7359 296 Pfam PF03466 LysR substrate binding domain 88 290 1.8E-34 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_17860 f751f5f82e6a73a01bd5034858ca7359 296 Gene3D G3DSA:1.10.10.10 1 81 1.9E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17860 f751f5f82e6a73a01bd5034858ca7359 296 SUPERFAMILY SSF53850 89 293 1.16E-33 T 12-10-2018 AFR_17860 f751f5f82e6a73a01bd5034858ca7359 296 Gene3D G3DSA:3.40.190.10 92 273 4.6E-36 T 12-10-2018 AFR_12295 7aa08797655cd5bfa3b402984bcaf415 302 Gene3D G3DSA:3.40.50.1820 10 284 8.6E-73 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12295 7aa08797655cd5bfa3b402984bcaf415 302 Gene3D G3DSA:1.10.10.800 138 226 8.6E-73 T 12-10-2018 AFR_12295 7aa08797655cd5bfa3b402984bcaf415 302 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 6 162 7.2E-5 T 12-10-2018 IPR010520 UPF0255 family AFR_12295 7aa08797655cd5bfa3b402984bcaf415 302 SUPERFAMILY SSF53474 3 295 1.92E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11210 a56ccc13f37ad0adba2a77eba4e83434 307 SUPERFAMILY SSF161098 33 307 1.87E-65 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11210 a56ccc13f37ad0adba2a77eba4e83434 307 Gene3D G3DSA:1.10.3720.10 23 298 8.7E-63 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11210 a56ccc13f37ad0adba2a77eba4e83434 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 301 1.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_11330 c59ba6a67914054ec1811d8e2bf5efa6 158 SUPERFAMILY SSF55811 12 134 1.76E-34 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_11330 c59ba6a67914054ec1811d8e2bf5efa6 158 Pfam PF00293 NUDIX domain 16 128 1.4E-21 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_11330 c59ba6a67914054ec1811d8e2bf5efa6 158 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_11330 c59ba6a67914054ec1811d8e2bf5efa6 158 Gene3D G3DSA:3.90.79.10 1 132 7.8E-38 T 12-10-2018 AFR_11330 c59ba6a67914054ec1811d8e2bf5efa6 158 PRINTS PR00502 NUDIX hydrolase family signature 54 69 3.5E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_11330 c59ba6a67914054ec1811d8e2bf5efa6 158 PRINTS PR00502 NUDIX hydrolase family signature 40 54 3.5E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_01605 9b88ace9db943b238e0eede1fce88453 520 Gene3D G3DSA:3.30.920.50 221 335 1.0E-111 T 12-10-2018 AFR_01605 9b88ace9db943b238e0eede1fce88453 520 Gene3D G3DSA:2.80.10.50 397 518 1.3E-34 T 12-10-2018 AFR_01605 9b88ace9db943b238e0eede1fce88453 520 SMART SM00458 394 520 5.3E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_01605 9b88ace9db943b238e0eede1fce88453 520 Pfam PF00652 Ricin-type beta-trefoil lectin domain 403 517 1.0E-22 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_01605 9b88ace9db943b238e0eede1fce88453 520 Gene3D G3DSA:2.60.110.10 26 360 1.0E-111 T 12-10-2018 IPR037176 Osmotin/thaumatin-like superfamily AFR_01605 9b88ace9db943b238e0eede1fce88453 520 Pfam PF16483 Beta-1,3-glucanase 22 375 2.0E-99 T 12-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 AFR_01605 9b88ace9db943b238e0eede1fce88453 520 SUPERFAMILY SSF50370 389 518 7.97E-34 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_09585 b0bba9a286991c805bfa5abe921f7c74 250 SMART SM00563 35 154 1.6E-34 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_09585 b0bba9a286991c805bfa5abe921f7c74 250 SUPERFAMILY SSF69593 3 217 2.22E-51 T 12-10-2018 AFR_09585 b0bba9a286991c805bfa5abe921f7c74 250 Pfam PF01553 Acyltransferase 22 150 2.7E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 Pfam PF12245 Bacterial Ig-like domain (group 3) 296 309 2.7 T 12-10-2018 IPR022038 Bacterial Ig-like domain AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 Pfam PF12245 Bacterial Ig-like domain (group 3) 202 221 0.0024 T 12-10-2018 IPR022038 Bacterial Ig-like domain AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 108 122 - T 12-10-2018 IPR028871 Blue (type 1) copper protein, binding site AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 46 128 2.4E-4 T 12-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 SUPERFAMILY SSF49503 32 129 3.75E-10 T 12-10-2018 IPR008972 Cupredoxin AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 Gene3D G3DSA:2.60.40.420 26 128 3.0E-7 T 12-10-2018 IPR008972 Cupredoxin AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 Gene3D G3DSA:2.60.40.10 136 227 1.5E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 Gene3D G3DSA:2.60.40.10 320 408 4.4E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_15625 de24512b49fcbfc5e29ab22d3f66ec35 498 Gene3D G3DSA:2.60.40.10 232 319 1.4E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_31460 9999b8af16900c2268908f9910693679 118 Pfam PF01638 HxlR-like helix-turn-helix 24 103 6.6E-16 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_31460 9999b8af16900c2268908f9910693679 118 SUPERFAMILY SSF46785 8 111 1.05E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31460 9999b8af16900c2268908f9910693679 118 Gene3D G3DSA:1.10.10.10 2 114 5.7E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20885 8cd56ce61dfa97750063d78f51babbcc 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 171 1.4E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_20885 8cd56ce61dfa97750063d78f51babbcc 190 SUPERFAMILY SSF88946 4 109 7.38E-26 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_20885 8cd56ce61dfa97750063d78f51babbcc 190 Gene3D G3DSA:1.10.10.10 84 175 9.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20885 8cd56ce61dfa97750063d78f51babbcc 190 SUPERFAMILY SSF88659 110 172 2.62E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_20885 8cd56ce61dfa97750063d78f51babbcc 190 Pfam PF08281 Sigma-70, region 4 119 168 1.7E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_20885 8cd56ce61dfa97750063d78f51babbcc 190 Pfam PF04542 Sigma-70 region 2 23 90 4.9E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_20885 8cd56ce61dfa97750063d78f51babbcc 190 Gene3D G3DSA:1.10.1740.10 4 83 3.7E-26 T 12-10-2018 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 8.5E-45 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 Gene3D G3DSA:1.10.720.90 2 55 4.0E-19 T 12-10-2018 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.842 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 Gene3D G3DSA:1.10.1900.20 56 119 2.7E-26 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 SUPERFAMILY SSF74731 3 116 2.75E-44 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.5E-37 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.5E-37 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.5E-37 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 1.0E-19 T 12-10-2018 AFR_30455 6b22ca3ac134caa7c37aa45843885c86 130 Pfam PF00453 Ribosomal protein L20 3 109 1.6E-43 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_34495 9362b1688df4a1435596f29d252cb5d9 142 SMART SM00860 14 139 2.0E-7 T 12-10-2018 IPR018958 Knr4/Smi1-like domain AFR_34495 9362b1688df4a1435596f29d252cb5d9 142 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 14 138 1.6E-12 T 12-10-2018 IPR018958 Knr4/Smi1-like domain AFR_34495 9362b1688df4a1435596f29d252cb5d9 142 Gene3D G3DSA:3.40.1580.10 8 142 1.2E-13 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily AFR_34495 9362b1688df4a1435596f29d252cb5d9 142 SUPERFAMILY SSF160631 11 139 3.14E-14 T 12-10-2018 AFR_32965 f4956af12a40824531f297243a52233b 415 PRINTS PR01988 Putative bacilysin exporter bacE signature 297 320 3.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32965 f4956af12a40824531f297243a52233b 415 PRINTS PR01988 Putative bacilysin exporter bacE signature 16 38 3.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32965 f4956af12a40824531f297243a52233b 415 PRINTS PR01988 Putative bacilysin exporter bacE signature 143 164 3.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32965 f4956af12a40824531f297243a52233b 415 PRINTS PR01988 Putative bacilysin exporter bacE signature 170 187 3.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 AFR_32965 f4956af12a40824531f297243a52233b 415 SUPERFAMILY SSF103473 14 401 1.29E-35 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_32965 f4956af12a40824531f297243a52233b 415 Pfam PF05977 Transmembrane secretion effector 14 399 6.2E-29 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_32965 f4956af12a40824531f297243a52233b 415 Gene3D G3DSA:1.20.1250.20 11 397 3.1E-31 T 12-10-2018 AFR_17215 cc3ee12d76a2e861c22e9321cf9168cf 159 Pfam PF11188 Protein of unknown function (DUF2975) 34 159 5.8E-31 T 12-10-2018 IPR021354 Protein of unknown function DUF2975 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 354 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 379 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 340 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 398 7.5E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 SUPERFAMILY SSF55874 234 399 2.75E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 Gene3D G3DSA:3.30.565.10 252 400 5.6E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 244 1.5E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 399 1.5E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 Gene3D G3DSA:3.30.450.40 13 167 9.5E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 SMART SM00065 25 167 0.0087 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 Gene3D G3DSA:1.10.287.130 171 248 1.2E-24 T 12-10-2018 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 SMART SM00387 290 400 1.3E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 SUPERFAMILY SSF47384 168 244 1.0E-22 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 Pfam PF01590 GAF domain 33 157 4.9E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 SUPERFAMILY SSF55781 27 163 2.45E-22 T 12-10-2018 AFR_42215 bed59d88c5808b48a0c410691df5cd49 400 SMART SM00388 179 245 1.7E-23 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_04320 ecf42e2af5852b5a1aaf2788459067db 274 SUPERFAMILY SSF55729 141 267 2.57E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_04320 ecf42e2af5852b5a1aaf2788459067db 274 Gene3D G3DSA:3.40.630.30 96 271 7.8E-26 T 12-10-2018 AFR_04320 ecf42e2af5852b5a1aaf2788459067db 274 Pfam PF08445 FR47-like protein 198 267 8.2E-8 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_34995 4d8721fa021fc45d317b7dfda2f1f899 302 Gene3D G3DSA:2.60.200.40 129 289 1.5E-35 T 12-10-2018 AFR_34995 4d8721fa021fc45d317b7dfda2f1f899 302 SUPERFAMILY SSF111331 3 299 1.35E-61 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_34995 4d8721fa021fc45d317b7dfda2f1f899 302 Gene3D G3DSA:3.40.50.10330 3 128 2.7E-23 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_34995 4d8721fa021fc45d317b7dfda2f1f899 302 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 46 297 2.1E-39 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase AFR_34995 4d8721fa021fc45d317b7dfda2f1f899 302 Pfam PF00781 Diacylglycerol kinase catalytic domain 21 128 1.6E-18 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFR_04665 7ad01f8f8ad96a67c9564466d135a52b 271 SUPERFAMILY SSF55120 4 256 2.3E-69 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_04665 7ad01f8f8ad96a67c9564466d135a52b 271 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 7 248 5.2E-51 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_04665 7ad01f8f8ad96a67c9564466d135a52b 271 Gene3D G3DSA:3.30.70.660 114 252 9.1E-38 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 AFR_04665 7ad01f8f8ad96a67c9564466d135a52b 271 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 5 253 31.249 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_04665 7ad01f8f8ad96a67c9564466d135a52b 271 Pfam PF01416 tRNA pseudouridine synthase 152 253 2.4E-23 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_04665 7ad01f8f8ad96a67c9564466d135a52b 271 PIRSF PIRSF001430 4 270 1.6E-73 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_04665 7ad01f8f8ad96a67c9564466d135a52b 271 Gene3D G3DSA:3.30.70.580 2 113 1.1E-31 T 12-10-2018 AFR_39875 472c1bc47c12515126f48fa1b42bdaed 190 Gene3D G3DSA:3.40.430.10 2 186 4.7E-40 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_39875 472c1bc47c12515126f48fa1b42bdaed 190 SUPERFAMILY SSF53597 2 189 3.01E-31 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_39875 472c1bc47c12515126f48fa1b42bdaed 190 Pfam PF01872 RibD C-terminal domain 2 182 1.4E-13 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_31855 6718554b726788a98ca23a9f17f3cfbe 233 SUPERFAMILY SSF102588 3 220 2.09E-26 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_31855 6718554b726788a98ca23a9f17f3cfbe 233 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 146 1.9E-8 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 AFR_31855 6718554b726788a98ca23a9f17f3cfbe 233 Gene3D G3DSA:3.40.50.10320 2 228 3.8E-29 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 161 3.8E-43 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 Gene3D G3DSA:1.10.10.10 87 163 4.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 159 3.2E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 Gene3D G3DSA:1.10.1740.10 3 79 2.0E-11 T 12-10-2018 AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 Pfam PF04542 Sigma-70 region 2 19 80 9.2E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 SUPERFAMILY SSF88946 2 91 3.92E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 Pfam PF08281 Sigma-70, region 4 105 156 6.9E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_37740 6ba54e53668cd5dd2d569b1e5bcbe7d7 171 SUPERFAMILY SSF88659 98 161 2.06E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_29675 b7ce9e1b319396038b3561f14792998f 300 SUPERFAMILY SSF56752 12 290 7.72E-70 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFR_29675 b7ce9e1b319396038b3561f14792998f 300 Gene3D G3DSA:3.30.470.10 2 130 3.3E-28 T 12-10-2018 AFR_29675 b7ce9e1b319396038b3561f14792998f 300 Gene3D G3DSA:3.20.10.10 131 297 1.5E-48 T 12-10-2018 AFR_29675 b7ce9e1b319396038b3561f14792998f 300 Pfam PF01063 Amino-transferase class IV 41 266 7.2E-40 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFR_37950 1a4e933a3116ee515d3fb1896946563d 258 SUPERFAMILY SSF69593 46 192 1.18E-25 T 12-10-2018 AFR_37950 1a4e933a3116ee515d3fb1896946563d 258 SMART SM00563 81 193 1.0E-33 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_37950 1a4e933a3116ee515d3fb1896946563d 258 Pfam PF01553 Acyltransferase 79 190 2.0E-22 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_11835 892c39e49557dddae7e9e48d431dde1f 408 Gene3D G3DSA:1.20.1250.20 7 392 9.5E-35 T 12-10-2018 AFR_11835 892c39e49557dddae7e9e48d431dde1f 408 Pfam PF05977 Transmembrane secretion effector 6 396 4.5E-26 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_11835 892c39e49557dddae7e9e48d431dde1f 408 SUPERFAMILY SSF103473 10 405 7.32E-41 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_35245 80e69b244a237e298facb6ed11e7a9d0 439 SUPERFAMILY SSF50998 84 344 3.92E-11 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_35245 80e69b244a237e298facb6ed11e7a9d0 439 Pfam PF13360 PQQ-like domain 179 320 4.7E-11 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_02120 d34a46bdf51b0b6a8de99016b98d3d5a 267 Pfam PF11228 Protein of unknown function (DUF3027) 30 222 3.7E-83 T 12-10-2018 IPR021391 Protein of unknown function DUF3027 AFR_05895 9d3f2c5b64e66e9f5788eec7fb6c157e 185 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 2 182 24.827 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 AFR_05895 9d3f2c5b64e66e9f5788eec7fb6c157e 185 Pfam PF02622 Uncharacterized ACR, COG1678 13 169 1.4E-37 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 AFR_05895 9d3f2c5b64e66e9f5788eec7fb6c157e 185 SUPERFAMILY SSF143456 2 177 7.98E-47 T 12-10-2018 AFR_05895 9d3f2c5b64e66e9f5788eec7fb6c157e 185 Gene3D G3DSA:3.40.1740.10 1 174 2.3E-60 T 12-10-2018 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 SMART SM00448 2 115 3.6E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 SUPERFAMILY SSF52172 2 133 4.27E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 SMART SM00421 148 205 2.2E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 SUPERFAMILY SSF46894 134 206 8.84E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 Pfam PF00072 Response regulator receiver domain 4 114 7.6E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 Gene3D G3DSA:3.40.50.12740 2 207 8.5E-66 T 12-10-2018 AFR_32825 d06148a23ec8de9d31d298045b4b3e74 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 1.2E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_28980 5ef1a7dfef90002351f1fdde7157af06 119 Pfam PF07883 Cupin domain 38 102 6.3E-15 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_28980 5ef1a7dfef90002351f1fdde7157af06 119 Gene3D G3DSA:2.60.120.10 2 109 3.9E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_28980 5ef1a7dfef90002351f1fdde7157af06 119 SUPERFAMILY SSF51182 27 105 8.91E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 SMART SM00344 26 135 3.6E-33 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 Pfam PF13412 Winged helix-turn-helix DNA-binding 26 73 1.5E-15 T 12-10-2018 AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 Gene3D G3DSA:3.30.70.920 78 169 1.5E-13 T 12-10-2018 AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 53 72 8.1E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 42 8.1E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 42 53 8.1E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 Gene3D G3DSA:1.10.10.10 19 77 4.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 SUPERFAMILY SSF54909 92 165 2.01E-9 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 SUPERFAMILY SSF46785 25 85 2.57E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16120 b5b450657df2316fd71f762fa34eb35a 181 Pfam PF01037 Lrp/AsnC ligand binding domain 102 164 1.8E-9 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_13265 2b48d46bf2067d924fc0fbb3169c7218 380 Pfam PF01757 Acyltransferase family 27 349 5.3E-23 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 SUPERFAMILY SSF75011 64 318 5.23E-10 T 12-10-2018 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 Gene3D G3DSA:2.60.40.10 580 665 2.6E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_12055 0e28bd108346cdf858481184e1b962d5 860 Gene3D G3DSA:2.60.40.10 482 577 5.3E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_12055 0e28bd108346cdf858481184e1b962d5 860 SUPERFAMILY SSF49265 581 744 7.47E-15 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 SMART SM00060 396 470 2.4E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 SMART SM00060 669 742 2.5E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 SMART SM00060 582 658 3.1E-6 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 SMART SM00060 485 566 3.7E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 Gene3D G3DSA:2.60.40.10 666 754 2.0E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_12055 0e28bd108346cdf858481184e1b962d5 860 Gene3D G3DSA:2.60.40.10 392 481 1.9E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_12055 0e28bd108346cdf858481184e1b962d5 860 Pfam PF00041 Fibronectin type III domain 398 472 2.5E-9 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_12055 0e28bd108346cdf858481184e1b962d5 860 SUPERFAMILY SSF49265 395 572 5.79E-24 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 Gene3D G3DSA:3.30.420.40 175 304 2.2E-74 T 12-10-2018 AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 PIRSF PIRSF019169 1 341 2.2E-79 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 Gene3D G3DSA:3.30.1490.300 82 139 2.2E-74 T 12-10-2018 AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 SUPERFAMILY SSF53067 7 170 4.21E-13 T 12-10-2018 AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 Pfam PF11104 Type IV pilus assembly protein PilM; 8 337 9.6E-48 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 SMART SM00842 6 171 8.4E-8 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 7 337 2.1E-47 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 SUPERFAMILY SSF53067 179 337 2.67E-17 T 12-10-2018 AFR_05970 00ed0176d9c811d029ed9a12255f077d 341 Gene3D G3DSA:3.30.420.40 7 337 2.2E-74 T 12-10-2018 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 SUPERFAMILY SSF53474 4 272 3.4E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 3.8E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 3.8E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 3.8E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 3.8E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 Gene3D G3DSA:3.40.50.1820 4 283 1.6E-97 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 Pfam PF12697 Alpha/beta hydrolase family 30 266 7.8E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00412 Epoxide hydrolase signature 56 71 1.4E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00412 Epoxide hydrolase signature 101 114 1.4E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00412 Epoxide hydrolase signature 249 271 1.4E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28670 5b46763e7be0c32793bdf5211fbbe4fd 284 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.4E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_16060 e90d60d4c54632b0f5ad170bf6b84781 616 Gene3D G3DSA:3.10.180.10 426 613 1.6E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16060 e90d60d4c54632b0f5ad170bf6b84781 616 Gene3D G3DSA:3.10.180.10 286 424 1.1E-15 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16060 e90d60d4c54632b0f5ad170bf6b84781 616 SUPERFAMILY SSF51658 5 272 5.53E-73 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_16060 e90d60d4c54632b0f5ad170bf6b84781 616 Pfam PF01261 Xylose isomerase-like TIM barrel 22 221 7.6E-35 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_16060 e90d60d4c54632b0f5ad170bf6b84781 616 Gene3D G3DSA:3.20.20.150 1 272 1.2E-70 T 12-10-2018 AFR_16060 e90d60d4c54632b0f5ad170bf6b84781 616 SUPERFAMILY SSF54593 288 606 7.52E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_30960 e83d19261354244a3852f8cd30e65136 528 SUPERFAMILY SSF103473 14 401 2.75E-48 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_30960 e83d19261354244a3852f8cd30e65136 528 Gene3D G3DSA:1.20.1250.20 9 398 4.9E-40 T 12-10-2018 AFR_30960 e83d19261354244a3852f8cd30e65136 528 Pfam PF05977 Transmembrane secretion effector 7 522 2.8E-155 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_16695 779d5e481dd33866a28a11e66bef83b0 221 Pfam PF13847 Methyltransferase domain 11 125 4.3E-13 T 12-10-2018 IPR025714 Methyltransferase domain AFR_16695 779d5e481dd33866a28a11e66bef83b0 221 Gene3D G3DSA:3.40.50.150 1 219 6.9E-67 T 12-10-2018 AFR_16695 779d5e481dd33866a28a11e66bef83b0 221 SUPERFAMILY SSF53335 2 219 1.24E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_19485 b5fafad954e5b57b67a73ea7172f06a4 114 Gene3D G3DSA:3.10.180.10 1 113 2.3E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_19485 b5fafad954e5b57b67a73ea7172f06a4 114 SUPERFAMILY SSF54593 8 112 3.76E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_40910 23396b7edd1c20fd03d59b1ced04a273 330 SUPERFAMILY SSF52540 3 231 5.69E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40910 23396b7edd1c20fd03d59b1ced04a273 330 Pfam PF00005 ABC transporter 24 164 2.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_40910 23396b7edd1c20fd03d59b1ced04a273 330 SMART SM00382 33 220 5.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_40910 23396b7edd1c20fd03d59b1ced04a273 330 Gene3D G3DSA:3.40.50.300 1 275 3.1E-58 T 12-10-2018 AFR_40910 23396b7edd1c20fd03d59b1ced04a273 330 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_42280 f60d1d67db61649878547b3a26e6c42b 115 SUPERFAMILY SSF46785 22 97 1.97E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_42280 f60d1d67db61649878547b3a26e6c42b 115 Gene3D G3DSA:1.10.10.10 6 106 4.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42280 f60d1d67db61649878547b3a26e6c42b 115 Pfam PF03551 Transcriptional regulator PadR-like family 25 90 2.6E-6 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_41205 b15ef9bc8a20add8db546b580189b909 152 Gene3D G3DSA:3.30.530.20 2 152 8.7E-18 T 12-10-2018 IPR023393 START-like domain superfamily AFR_41205 b15ef9bc8a20add8db546b580189b909 152 SUPERFAMILY SSF55961 2 150 4.36E-21 T 12-10-2018 AFR_41205 b15ef9bc8a20add8db546b580189b909 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 151 2.9E-14 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_16555 44b2dcd95e58b607ba760c4df27d1a11 298 SUPERFAMILY SSF51556 1 293 1.18E-28 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_16555 44b2dcd95e58b607ba760c4df27d1a11 298 Gene3D G3DSA:3.20.20.140 1 294 2.6E-29 T 12-10-2018 AFR_00835 76ac23cf952cefb77006954e56b7a29d 103 Gene3D G3DSA:3.30.750.24 7 103 5.0E-22 T 12-10-2018 IPR036513 STAS domain superfamily AFR_00835 76ac23cf952cefb77006954e56b7a29d 103 Pfam PF13466 STAS domain 17 97 3.3E-14 T 12-10-2018 IPR002645 STAS domain AFR_00835 76ac23cf952cefb77006954e56b7a29d 103 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 7 102 1.1E-16 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_00835 76ac23cf952cefb77006954e56b7a29d 103 SUPERFAMILY SSF52091 6 102 2.75E-18 T 12-10-2018 IPR036513 STAS domain superfamily AFR_29090 09d47d97e58b9b305a3513be0b7c1101 336 SUPERFAMILY SSF51430 13 313 3.4E-59 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_29090 09d47d97e58b9b305a3513be0b7c1101 336 Gene3D G3DSA:3.20.20.100 9 314 7.4E-62 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_29090 09d47d97e58b9b305a3513be0b7c1101 336 Pfam PF00248 Aldo/keto reductase family 15 304 2.3E-47 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_28010 f8df30913dc9f577b3f3239455259db4 220 Pfam PF02210 Laminin G domain 98 203 5.3E-11 T 12-10-2018 IPR001791 Laminin G domain AFR_28010 f8df30913dc9f577b3f3239455259db4 220 SUPERFAMILY SSF49899 75 217 2.7E-18 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_28010 f8df30913dc9f577b3f3239455259db4 220 SMART SM00282 90 220 2.8E-6 T 12-10-2018 IPR001791 Laminin G domain AFR_28010 f8df30913dc9f577b3f3239455259db4 220 Gene3D G3DSA:2.60.120.200 71 219 7.2E-18 T 12-10-2018 AFR_19305 84dfe0aeaaae8fee45a58e2a279658a9 263 SUPERFAMILY SSF161098 58 240 3.92E-22 T 12-10-2018 IPR035906 MetI-like superfamily AFR_19305 84dfe0aeaaae8fee45a58e2a279658a9 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 249 9.0E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_19305 84dfe0aeaaae8fee45a58e2a279658a9 263 Gene3D G3DSA:1.10.3720.10 54 250 2.6E-16 T 12-10-2018 IPR035906 MetI-like superfamily AFR_00780 824ee5cc25793fc4d68532692188a891 123 SUPERFAMILY SSF50475 5 103 2.75E-16 T 12-10-2018 AFR_00780 824ee5cc25793fc4d68532692188a891 123 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 2 120 9.8E-45 T 12-10-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative AFR_00780 824ee5cc25793fc4d68532692188a891 123 Gene3D G3DSA:2.30.110.10 2 121 9.7E-18 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_00780 824ee5cc25793fc4d68532692188a891 123 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 80 6.4E-8 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_02735 93a10d26273c3060863a0d8023fd1678 147 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 49 1.7E-14 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_02735 93a10d26273c3060863a0d8023fd1678 147 Gene3D G3DSA:1.10.1660.10 3 55 7.4E-14 T 12-10-2018 AFR_02735 93a10d26273c3060863a0d8023fd1678 147 Pfam PF12728 Helix-turn-helix domain 5 49 3.0E-15 T 12-10-2018 AFR_02735 93a10d26273c3060863a0d8023fd1678 147 SUPERFAMILY SSF46955 5 53 2.2E-9 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_02870 9e36c95080b99503a2d3ad9d6c0dc9dc 310 SUPERFAMILY SSF161098 73 293 1.1E-55 T 12-10-2018 IPR035906 MetI-like superfamily AFR_02870 9e36c95080b99503a2d3ad9d6c0dc9dc 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 300 2.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_02870 9e36c95080b99503a2d3ad9d6c0dc9dc 310 Gene3D G3DSA:1.10.3720.10 69 302 4.5E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30115 0a5ede58329ac980215a85e690270d42 161 Pfam PF02080 TrkA-C domain 88 156 5.9E-13 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFR_30115 0a5ede58329ac980215a85e690270d42 161 Gene3D G3DSA:3.30.70.1450 87 159 3.2E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_30115 0a5ede58329ac980215a85e690270d42 161 PIRSF PIRSF005028 1 161 2.7E-45 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT AFR_30115 0a5ede58329ac980215a85e690270d42 161 SUPERFAMILY SSF116726 83 156 1.96E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_16585 8c042055909e8ac709693f79d71f8606 466 Gene3D G3DSA:3.40.50.620 315 461 3.4E-32 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_16585 8c042055909e8ac709693f79d71f8606 466 Pfam PF00294 pfkB family carbohydrate kinase 4 295 1.3E-22 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_16585 8c042055909e8ac709693f79d71f8606 466 Pfam PF01467 Cytidylyltransferase-like 330 421 3.0E-14 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_16585 8c042055909e8ac709693f79d71f8606 466 SUPERFAMILY SSF52374 328 458 2.58E-21 T 12-10-2018 AFR_16585 8c042055909e8ac709693f79d71f8606 466 Gene3D G3DSA:3.40.1190.20 1 300 1.6E-67 T 12-10-2018 IPR029056 Ribokinase-like AFR_16585 8c042055909e8ac709693f79d71f8606 466 SUPERFAMILY SSF53613 6 293 2.18E-33 T 12-10-2018 IPR029056 Ribokinase-like AFR_16585 8c042055909e8ac709693f79d71f8606 466 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_16585 8c042055909e8ac709693f79d71f8606 466 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 327 392 1.4E-13 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_34900 bb779b1023575e0b2cc68a06f81eb200 146 Gene3D G3DSA:3.30.530.20 5 145 9.1E-29 T 12-10-2018 IPR023393 START-like domain superfamily AFR_34900 bb779b1023575e0b2cc68a06f81eb200 146 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 142 6.0E-18 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_34900 bb779b1023575e0b2cc68a06f81eb200 146 SUPERFAMILY SSF55961 10 142 3.0E-27 T 12-10-2018 AFR_28505 f14b69c348c9bc26940579e395dc2ec5 219 Pfam PF00072 Response regulator receiver domain 3 112 2.0E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28505 f14b69c348c9bc26940579e395dc2ec5 219 Gene3D G3DSA:1.10.10.10 122 219 6.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28505 f14b69c348c9bc26940579e395dc2ec5 219 SMART SM00862 145 217 1.7E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28505 f14b69c348c9bc26940579e395dc2ec5 219 SMART SM00448 1 112 1.6E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_28505 f14b69c348c9bc26940579e395dc2ec5 219 SUPERFAMILY SSF52172 2 170 1.11E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_28505 f14b69c348c9bc26940579e395dc2ec5 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 1.1E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_28505 f14b69c348c9bc26940579e395dc2ec5 219 Gene3D G3DSA:3.40.50.2300 1 121 4.5E-30 T 12-10-2018 AFR_11560 80edea2f960fcefb67de47fb0f89b638 154 Pfam PF00652 Ricin-type beta-trefoil lectin domain 35 149 1.7E-9 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_11560 80edea2f960fcefb67de47fb0f89b638 154 SUPERFAMILY SSF50370 33 151 4.57E-16 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_11560 80edea2f960fcefb67de47fb0f89b638 154 SMART SM00458 32 152 2.0E-4 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_11560 80edea2f960fcefb67de47fb0f89b638 154 Gene3D G3DSA:2.80.10.50 36 152 9.4E-10 T 12-10-2018 AFR_33995 5b4052e960ed152284ce1690764e1116 247 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 236 3.8E-67 T 12-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 AFR_33995 5b4052e960ed152284ce1690764e1116 247 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 237 3.5E-49 T 12-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 AFR_30280 ee22e03034a60a910c2985831ea744c9 279 Pfam PF13560 Helix-turn-helix domain 5 84 9.2E-16 T 12-10-2018 AFR_30280 ee22e03034a60a910c2985831ea744c9 279 Gene3D G3DSA:3.30.450.180 104 278 2.0E-10 T 12-10-2018 AFR_30280 ee22e03034a60a910c2985831ea744c9 279 Gene3D G3DSA:1.10.260.40 26 94 3.7E-10 T 12-10-2018 AFR_30280 ee22e03034a60a910c2985831ea744c9 279 SUPERFAMILY SSF47413 29 79 2.64E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_30280 ee22e03034a60a910c2985831ea744c9 279 SMART SM00530 9 81 1.6E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_36775 a93348885575bacc85bcc39d610cd660 225 Gene3D G3DSA:3.40.50.2300 1 124 4.4E-37 T 12-10-2018 AFR_36775 a93348885575bacc85bcc39d610cd660 225 Gene3D G3DSA:1.10.10.10 125 224 2.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36775 a93348885575bacc85bcc39d610cd660 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 222 9.9E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_36775 a93348885575bacc85bcc39d610cd660 225 SMART SM00448 1 118 6.0E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_36775 a93348885575bacc85bcc39d610cd660 225 Pfam PF00072 Response regulator receiver domain 4 119 7.1E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_36775 a93348885575bacc85bcc39d610cd660 225 SUPERFAMILY SSF52172 1 178 9.96E-39 T 12-10-2018 IPR011006 CheY-like superfamily AFR_36775 a93348885575bacc85bcc39d610cd660 225 SMART SM00862 151 222 7.0E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_19945 9e93b98b147235f9a0ab227e260e5f33 714 SUPERFAMILY SSF56601 249 713 1.19E-60 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_19945 9e93b98b147235f9a0ab227e260e5f33 714 Pfam PF00912 Transglycosylase 79 262 5.4E-57 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_19945 9e93b98b147235f9a0ab227e260e5f33 714 Gene3D G3DSA:1.10.3810.10 69 278 7.4E-68 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_19945 9e93b98b147235f9a0ab227e260e5f33 714 SUPERFAMILY SSF53955 64 284 5.34E-64 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_19945 9e93b98b147235f9a0ab227e260e5f33 714 Gene3D G3DSA:3.40.710.10 311 714 7.0E-59 T 12-10-2018 AFR_19945 9e93b98b147235f9a0ab227e260e5f33 714 Pfam PF00905 Penicillin binding protein transpeptidase domain 427 672 5.3E-20 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 Pfam PF00553 Cellulose binding domain 32 131 3.2E-32 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 78 91 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 SUPERFAMILY SSF75005 175 441 2.09E-31 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 SMART SM00637 32 131 6.1E-44 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 Gene3D G3DSA:2.115.10.20 152 457 2.5E-141 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 Gene3D G3DSA:2.60.40.290 25 134 6.2E-35 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 Pfam PF03664 Glycosyl hydrolase family 62 156 426 1.2E-151 T 12-10-2018 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_14900 99fa29dcbc59a877e4e248749c28463c 457 SUPERFAMILY SSF49384 29 133 1.95E-31 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_18065 b911d026d0a5511d00f1670a1370c6fe 351 Gene3D G3DSA:3.20.20.100 1 341 1.1E-128 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_18065 b911d026d0a5511d00f1670a1370c6fe 351 PRINTS PR00069 Aldo-keto reductase signature 111 129 5.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_18065 b911d026d0a5511d00f1670a1370c6fe 351 PRINTS PR00069 Aldo-keto reductase signature 47 71 5.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_18065 b911d026d0a5511d00f1670a1370c6fe 351 PRINTS PR00069 Aldo-keto reductase signature 142 159 5.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_18065 b911d026d0a5511d00f1670a1370c6fe 351 Pfam PF00248 Aldo/keto reductase family 16 318 9.7E-74 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_18065 b911d026d0a5511d00f1670a1370c6fe 351 SUPERFAMILY SSF51430 1 320 2.75E-105 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_21410 5e030832a91580e941b4baa23caafc3c 275 Pfam PF04951 D-aminopeptidase 1 264 1.9E-96 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase AFR_21410 5e030832a91580e941b4baa23caafc3c 275 SUPERFAMILY SSF63992 1 271 6.93E-89 T 12-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily AFR_21410 5e030832a91580e941b4baa23caafc3c 275 PIRSF PIRSF015853 1 274 2.2E-89 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase AFR_21410 5e030832a91580e941b4baa23caafc3c 275 Gene3D G3DSA:3.30.1360.130 120 262 7.1E-96 T 12-10-2018 AFR_21410 5e030832a91580e941b4baa23caafc3c 275 Gene3D G3DSA:3.40.50.10780 1 215 7.1E-96 T 12-10-2018 IPR027476 D-aminopeptidase, N-terminal AFR_30970 30af91e668297171ff8aaa528b7f3d9f 170 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 48 163 1.7E-19 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFR_30970 30af91e668297171ff8aaa528b7f3d9f 170 SUPERFAMILY SSF54637 20 163 1.12E-32 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_30970 30af91e668297171ff8aaa528b7f3d9f 170 Gene3D G3DSA:3.10.129.10 21 169 4.5E-38 T 12-10-2018 AFR_30970 30af91e668297171ff8aaa528b7f3d9f 170 Pfam PF03061 Thioesterase superfamily 78 156 1.2E-13 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFR_30410 c1a54a846da5bab5e5786cdb3bb79727 468 Gene3D G3DSA:2.60.40.10 382 466 1.2E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_30410 c1a54a846da5bab5e5786cdb3bb79727 468 Gene3D G3DSA:3.40.630.10 43 381 4.4E-62 T 12-10-2018 AFR_30410 c1a54a846da5bab5e5786cdb3bb79727 468 SUPERFAMILY SSF49265 376 458 1.66E-7 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_30410 c1a54a846da5bab5e5786cdb3bb79727 468 SUPERFAMILY SSF53187 48 379 1.41E-50 T 12-10-2018 AFR_30410 c1a54a846da5bab5e5786cdb3bb79727 468 Pfam PF04389 Peptidase family M28 132 341 7.5E-28 T 12-10-2018 IPR007484 Peptidase M28 AFR_08770 4b4c2ff6ec9f54276884121baa7cbe43 134 Gene3D G3DSA:2.60.120.460 1 133 2.8E-28 T 12-10-2018 IPR035917 YjbQ-like superfamily AFR_08770 4b4c2ff6ec9f54276884121baa7cbe43 134 SUPERFAMILY SSF111038 3 131 6.93E-31 T 12-10-2018 IPR035917 YjbQ-like superfamily AFR_08770 4b4c2ff6ec9f54276884121baa7cbe43 134 Pfam PF01894 Uncharacterised protein family UPF0047 18 129 2.0E-22 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFR_20170 69c804bf2ec279673debe890269f06f2 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 7.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20170 69c804bf2ec279673debe890269f06f2 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 7.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20170 69c804bf2ec279673debe890269f06f2 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 7.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20170 69c804bf2ec279673debe890269f06f2 139 SUPERFAMILY SSF46785 5 134 1.11E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20170 69c804bf2ec279673debe890269f06f2 139 Pfam PF13463 Winged helix DNA-binding domain 42 95 7.7E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20170 69c804bf2ec279673debe890269f06f2 139 SMART SM00347 22 122 1.9E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_20170 69c804bf2ec279673debe890269f06f2 139 Gene3D G3DSA:1.10.10.10 2 135 2.1E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33270 c873e6935abbc229ad08aa4f81b69407 292 Pfam PF08021 Siderophore-interacting FAD-binding domain 22 133 1.2E-30 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting AFR_33270 c873e6935abbc229ad08aa4f81b69407 292 Gene3D G3DSA:2.40.30.10 2 138 1.6E-32 T 12-10-2018 AFR_33270 c873e6935abbc229ad08aa4f81b69407 292 Pfam PF04954 Siderophore-interacting protein 153 287 1.2E-30 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain AFR_33270 c873e6935abbc229ad08aa4f81b69407 292 Gene3D G3DSA:3.40.50.80 148 292 8.4E-27 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 SMART SM00458 318 442 2.6E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 Gene3D G3DSA:2.80.10.50 314 411 2.9E-31 T 12-10-2018 AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 Pfam PF00652 Ricin-type beta-trefoil lectin domain 319 439 1.5E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 ProSitePatterns PS01095 Chitinases family 18 active site. 123 131 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 Gene3D G3DSA:3.20.20.80 38 290 1.7E-69 T 12-10-2018 AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 SUPERFAMILY SSF51445 19 313 5.11E-61 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 Gene3D G3DSA:3.40.5.30 225 259 1.7E-69 T 12-10-2018 AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 SUPERFAMILY SSF50370 313 441 1.49E-40 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 Pfam PF00704 Glycosyl hydrolases family 18 24 287 1.8E-44 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 Gene3D G3DSA:2.80.10.50 412 443 8.5E-10 T 12-10-2018 AFR_08740 32089a150fda5a43fc6dd3dcabcbd911 443 SMART SM00636 22 287 5.8E-45 T 12-10-2018 IPR011583 Chitinase II GO:0008061 AFR_17785 8e670f665b2b80f4729c10d013b8bdbd 294 Pfam PF13560 Helix-turn-helix domain 18 80 1.8E-13 T 12-10-2018 AFR_17785 8e670f665b2b80f4729c10d013b8bdbd 294 SUPERFAMILY SSF47413 15 76 6.52E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_17785 8e670f665b2b80f4729c10d013b8bdbd 294 Gene3D G3DSA:1.10.260.40 4 79 5.9E-7 T 12-10-2018 AFR_17785 8e670f665b2b80f4729c10d013b8bdbd 294 SMART SM00530 22 77 4.0E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_38595 21ff0db97251b8b998e1078046df563c 126 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 124 6.0E-23 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_38595 21ff0db97251b8b998e1078046df563c 126 SUPERFAMILY SSF55961 3 125 2.24E-34 T 12-10-2018 AFR_38595 21ff0db97251b8b998e1078046df563c 126 Gene3D G3DSA:3.30.530.20 1 126 9.3E-36 T 12-10-2018 IPR023393 START-like domain superfamily AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 Pfam PF13365 Trypsin-like peptidase domain 109 245 6.4E-32 T 12-10-2018 AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 Gene3D G3DSA:2.40.10.120 71 283 8.1E-66 T 12-10-2018 AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 PRINTS PR00834 HtrA/DegQ protease family signature 216 233 3.7E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 PRINTS PR00834 HtrA/DegQ protease family signature 238 255 3.7E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 PRINTS PR00834 HtrA/DegQ protease family signature 139 159 3.7E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 PRINTS PR00834 HtrA/DegQ protease family signature 180 204 3.7E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 PRINTS PR00834 HtrA/DegQ protease family signature 118 130 3.7E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_25065 c53e9715129ed52e1f6c716066929d7e 284 SUPERFAMILY SSF50494 82 279 1.17E-54 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 SMART SM00388 440 508 5.5E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 SUPERFAMILY SSF47384 427 504 2.55E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 SMART SM00387 552 666 8.1E-35 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 553 664 2.2E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 SUPERFAMILY SSF55785 302 432 2.21E-9 T 12-10-2018 IPR035965 PAS domain superfamily AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 592 606 4.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 650 663 4.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 625 643 4.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 Gene3D G3DSA:3.30.450.20 301 436 2.0E-9 T 12-10-2018 AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 Gene3D G3DSA:1.10.287.130 437 506 1.3E-9 T 12-10-2018 AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 SUPERFAMILY SSF55874 505 664 1.07E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 Gene3D G3DSA:3.30.565.10 510 669 4.7E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_08960 8cf1cd2e496c8f44f089b741094c51ae 678 Pfam PF00512 His Kinase A (phospho-acceptor) domain 443 505 1.1E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 161 7.0E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 Pfam PF04542 Sigma-70 region 2 18 80 7.9E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 Gene3D G3DSA:1.10.1740.10 5 83 1.3E-10 T 12-10-2018 AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 Gene3D G3DSA:1.10.10.10 84 164 1.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 SUPERFAMILY SSF88659 91 162 1.61E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 Pfam PF04545 Sigma-70, region 4 112 160 8.9E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 SUPERFAMILY SSF88946 8 95 1.14E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_32375 0e1ff1703d8e7deb76a37a1ec40f9efa 175 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 10 165 2.7E-47 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_03040 11571bfa33ede9676152572516b274e5 908 SUPERFAMILY SSF48452 16 91 1.33E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_03040 11571bfa33ede9676152572516b274e5 908 Pfam PF03704 Bacterial transcriptional activator domain 17 79 8.6E-10 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFR_03040 11571bfa33ede9676152572516b274e5 908 Gene3D G3DSA:1.25.40.10 1 94 3.7E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_03040 11571bfa33ede9676152572516b274e5 908 SUPERFAMILY SSF52540 104 360 5.57E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03040 11571bfa33ede9676152572516b274e5 908 Gene3D G3DSA:3.40.50.300 95 248 1.1E-9 T 12-10-2018 AFR_16180 0962eac6e04da3b8ce211a53ea69b0b4 572 SMART SM00220 63 345 3.5E-9 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_16180 0962eac6e04da3b8ce211a53ea69b0b4 572 Gene3D G3DSA:1.10.510.10 57 353 2.3E-34 T 12-10-2018 AFR_16180 0962eac6e04da3b8ce211a53ea69b0b4 572 SUPERFAMILY SSF56112 63 336 1.95E-34 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_16180 0962eac6e04da3b8ce211a53ea69b0b4 572 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 215 227 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_16180 0962eac6e04da3b8ce211a53ea69b0b4 572 Pfam PF00069 Protein kinase domain 73 296 4.9E-22 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_11750 19d34d7daed60cc0f5abbb7b7f72030f 128 SUPERFAMILY SSF54593 18 126 2.61E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_11750 19d34d7daed60cc0f5abbb7b7f72030f 128 Gene3D G3DSA:3.10.180.10 12 128 2.9E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_42230 97e783cda0aa717ddf7f87dbc88da611 234 Pfam PF00877 NlpC/P60 family 140 228 8.7E-20 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_42230 97e783cda0aa717ddf7f87dbc88da611 234 SUPERFAMILY SSF54001 124 227 1.54E-31 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_42230 97e783cda0aa717ddf7f87dbc88da611 234 Gene3D G3DSA:3.90.1720.10 40 231 1.7E-38 T 12-10-2018 AFR_38650 acca491d25d9e89f919f0ff146f63f37 377 Pfam PF02449 Beta-galactosidase 48 164 5.8E-7 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFR_38650 acca491d25d9e89f919f0ff146f63f37 377 SUPERFAMILY SSF51445 47 337 7.84E-10 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_38650 acca491d25d9e89f919f0ff146f63f37 377 Gene3D G3DSA:3.20.20.80 44 334 9.8E-14 T 12-10-2018 AFR_38935 73eb2523c6bf650804530bef4daae2f0 339 SUPERFAMILY SSF51735 3 313 3.85E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38935 73eb2523c6bf650804530bef4daae2f0 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 243 9.7E-54 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_38935 73eb2523c6bf650804530bef4daae2f0 339 Gene3D G3DSA:3.90.25.10 178 305 9.6E-79 T 12-10-2018 AFR_38935 73eb2523c6bf650804530bef4daae2f0 339 Gene3D G3DSA:3.40.50.720 9 243 9.6E-79 T 12-10-2018 AFR_16510 ba64617d68b577f854d84767f223cffd 507 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 84 205 1.4E-13 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFR_29930 dafb92dd37ba5d98b8dcb40241938920 397 Pfam PF01385 Probable transposase 153 274 4.4E-21 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFR_29930 dafb92dd37ba5d98b8dcb40241938920 397 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 315 5.0E-10 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_29930 dafb92dd37ba5d98b8dcb40241938920 397 Pfam PF07282 Putative transposase DNA-binding domain 288 356 1.3E-19 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_23255 0437c0cb82b538e0fdfb5b6a2bed24f6 454 Gene3D G3DSA:2.120.10.30 58 341 1.1E-11 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_23255 0437c0cb82b538e0fdfb5b6a2bed24f6 454 SUPERFAMILY SSF50952 67 452 6.93E-24 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_21795 2a1da42ccd7f93e526f0d6ac4800de02 415 Pfam PF13941 MutL protein 311 412 1.9E-18 T 12-10-2018 IPR006230 Protein MutL AFR_21795 2a1da42ccd7f93e526f0d6ac4800de02 415 Pfam PF13941 MutL protein 1 296 4.7E-95 T 12-10-2018 IPR006230 Protein MutL AFR_21795 2a1da42ccd7f93e526f0d6ac4800de02 415 SUPERFAMILY SSF53067 1 323 3.51E-5 T 12-10-2018 AFR_35165 ec4ed0d2690e31d9edde6150fde3bf86 235 SUPERFAMILY SSF54909 12 234 2.06E-76 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_35165 ec4ed0d2690e31d9edde6150fde3bf86 235 Pfam PF06778 Chlorite dismutase 37 224 5.4E-74 T 12-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase AFR_35165 ec4ed0d2690e31d9edde6150fde3bf86 235 Gene3D G3DSA:3.30.70.1100 131 234 6.3E-36 T 12-10-2018 AFR_38780 31b02b9ba8fe473019af095f22d0f687 282 SUPERFAMILY SSF102588 1 276 2.49E-64 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_38780 31b02b9ba8fe473019af095f22d0f687 282 Gene3D G3DSA:3.40.50.10320 1 281 5.1E-93 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_38780 31b02b9ba8fe473019af095f22d0f687 282 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 1 279 37.55 T 12-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 AFR_38780 31b02b9ba8fe473019af095f22d0f687 282 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 1 278 5.3E-102 T 12-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 AFR_38780 31b02b9ba8fe473019af095f22d0f687 282 Pfam PF02585 GlcNAc-PI de-N-acetylase 1 151 8.3E-26 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 AFR_00690 85fc5133218ee6fa795dab224038f4d7 150 Pfam PF02036 SCP-2 sterol transfer family 54 146 6.4E-15 T 12-10-2018 IPR003033 SCP2 sterol-binding domain AFR_00690 85fc5133218ee6fa795dab224038f4d7 150 Gene3D G3DSA:3.30.1050.10 38 149 1.7E-24 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_00690 85fc5133218ee6fa795dab224038f4d7 150 SUPERFAMILY SSF55718 39 146 8.95E-22 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_35385 a78cf6ecf94a525a3b97e6b73fec00a6 1054 Gene3D G3DSA:3.40.50.300 303 456 4.6E-7 T 12-10-2018 AFR_35385 a78cf6ecf94a525a3b97e6b73fec00a6 1054 SUPERFAMILY SSF52540 325 446 1.98E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04190 6d6e9b32314db5e6b3e76d2209c97ced 439 Pfam PF13347 MFS/sugar transport protein 19 434 3.9E-78 T 12-10-2018 AFR_04190 6d6e9b32314db5e6b3e76d2209c97ced 439 SUPERFAMILY SSF103473 13 429 6.67E-33 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_04190 6d6e9b32314db5e6b3e76d2209c97ced 439 Gene3D G3DSA:1.20.1250.20 14 430 2.2E-26 T 12-10-2018 AFR_26470 5216eef928bc39f86486f55cc7011ca0 850 Pfam PF02687 FtsX-like permease family 299 395 7.3E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_26470 5216eef928bc39f86486f55cc7011ca0 850 Pfam PF02687 FtsX-like permease family 752 842 1.2E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_26470 5216eef928bc39f86486f55cc7011ca0 850 Pfam PF12704 MacB-like periplasmic core domain 493 693 1.0E-11 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_26470 5216eef928bc39f86486f55cc7011ca0 850 Pfam PF12704 MacB-like periplasmic core domain 17 237 3.1E-12 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_14555 1b6e8715227406163abdb7e747664420 237 SUPERFAMILY SSF53474 5 232 2.47E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14555 1b6e8715227406163abdb7e747664420 237 Pfam PF12697 Alpha/beta hydrolase family 45 226 3.0E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_14555 1b6e8715227406163abdb7e747664420 237 Gene3D G3DSA:3.40.50.1820 2 232 6.4E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28055 c9772dedf13bff7d39c63a1bab4472d3 341 Gene3D G3DSA:2.120.10.30 39 340 1.3E-61 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_28055 c9772dedf13bff7d39c63a1bab4472d3 341 SUPERFAMILY SSF63829 11 335 1.26E-46 T 12-10-2018 AFR_28055 c9772dedf13bff7d39c63a1bab4472d3 341 Pfam PF03088 Strictosidine synthase 143 220 2.6E-19 T 12-10-2018 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 AFR_15350 133c94d1957b7fd4c39c77bc1d10c9e1 913 Pfam PF13086 AAA domain 230 564 6.7E-10 T 12-10-2018 AFR_15350 133c94d1957b7fd4c39c77bc1d10c9e1 913 Pfam PF13087 AAA domain 602 783 3.7E-17 T 12-10-2018 AFR_15350 133c94d1957b7fd4c39c77bc1d10c9e1 913 Gene3D G3DSA:3.40.50.300 611 801 2.4E-26 T 12-10-2018 AFR_15350 133c94d1957b7fd4c39c77bc1d10c9e1 913 SUPERFAMILY SSF52540 227 782 1.2E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15495 53c2fa5e88283152a0eba457e8d62922 351 SUPERFAMILY SSF55166 222 348 5.49E-17 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_15495 53c2fa5e88283152a0eba457e8d62922 351 Gene3D G3DSA:3.30.1380.10 176 350 1.5E-15 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFR_15495 53c2fa5e88283152a0eba457e8d62922 351 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 236 348 5.0E-12 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 SUPERFAMILY SSF55961 166 368 4.24E-46 T 12-10-2018 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 173 366 1.2E-46 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 SUPERFAMILY SSF50022 7 143 1.83E-43 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 173 195 1.7E-22 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 15 40 1.7E-22 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 45 60 1.7E-22 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 66 86 1.7E-22 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 129 155 1.7E-22 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 88 108 1.7E-22 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 Gene3D G3DSA:2.102.10.10 28 148 5.8E-36 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 Gene3D G3DSA:3.90.380.10 223 374 9.4E-31 T 12-10-2018 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 Gene3D G3DSA:3.90.380.10 149 222 2.3E-16 T 12-10-2018 AFR_18425 9d0b44d0e62d3a7ff6af6fe6b1e68215 383 Pfam PF00355 Rieske [2Fe-2S] domain 31 115 4.7E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 SUPERFAMILY SSF52540 3 400 4.46E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Pfam PF07517 SecA DEAD-like domain 5 387 5.8E-125 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Gene3D G3DSA:3.40.50.300 402 619 3.7E-91 T 12-10-2018 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 SUPERFAMILY SSF81886 620 947 4.71E-73 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Gene3D G3DSA:3.40.50.300 20 400 2.7E-169 T 12-10-2018 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 SMART SM00957 4 387 7.7E-267 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 SMART SM00958 226 343 1.0E-57 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 PRINTS PR00906 SecA protein signature 115 125 3.2E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 PRINTS PR00906 SecA protein signature 99 113 3.2E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 PRINTS PR00906 SecA protein signature 398 411 3.2E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 PRINTS PR00906 SecA protein signature 61 85 3.2E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 PRINTS PR00906 SecA protein signature 168 188 3.2E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 PRINTS PR00906 SecA protein signature 324 346 3.2E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 PRINTS PR00906 SecA protein signature 361 378 3.2E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Gene3D G3DSA:1.10.3060.10 621 836 1.1E-72 T 12-10-2018 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 821 0.0 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Gene3D G3DSA:3.90.1440.10 227 353 2.7E-169 T 12-10-2018 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 SUPERFAMILY SSF52540 401 618 8.79E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 835 19.699 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 SUPERFAMILY SSF81767 225 353 8.89E-38 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Pfam PF02810 SEC-C motif 939 956 2.7E-8 T 12-10-2018 IPR004027 SEC-C motif AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Pfam PF07516 SecA Wing and Scaffold domain 617 832 5.4E-65 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 ProSitePatterns PS01312 SecA family signature. 485 500 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Pfam PF01043 SecA preprotein cross-linking domain 231 343 2.7E-32 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFR_05800 ae8fe6c3310abc4cdaae93461f3b94b9 961 Gene3D G3DSA:3.10.450.50 916 957 2.5E-6 T 12-10-2018 AFR_26995 cedfe9e44b58b7d48f9d583677629957 172 SUPERFAMILY SSF55729 2 153 1.18E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_26995 cedfe9e44b58b7d48f9d583677629957 172 Gene3D G3DSA:3.40.630.30 1 157 5.5E-21 T 12-10-2018 AFR_26995 cedfe9e44b58b7d48f9d583677629957 172 Pfam PF13302 Acetyltransferase (GNAT) domain 4 141 4.5E-12 T 12-10-2018 IPR000182 GNAT domain AFR_31255 9e4fa2d60ab367bbee0f50be8af18954 502 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 13 303 4.4E-81 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_31255 9e4fa2d60ab367bbee0f50be8af18954 502 PRINTS PR00133 Glycosyl hydrolase family 3 signature 65 84 6.4E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_31255 9e4fa2d60ab367bbee0f50be8af18954 502 PRINTS PR00133 Glycosyl hydrolase family 3 signature 143 159 6.4E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_31255 9e4fa2d60ab367bbee0f50be8af18954 502 PRINTS PR00133 Glycosyl hydrolase family 3 signature 219 237 6.4E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_31255 9e4fa2d60ab367bbee0f50be8af18954 502 SUPERFAMILY SSF51445 12 306 2.0E-83 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_31255 9e4fa2d60ab367bbee0f50be8af18954 502 Gene3D G3DSA:3.20.20.300 7 317 9.0E-109 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_21440 3fad2dd434db59317493f55fc761490d 141 SUPERFAMILY SSF46785 14 139 3.91E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_21440 3fad2dd434db59317493f55fc761490d 141 Gene3D G3DSA:1.10.10.10 2 140 4.7E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21440 3fad2dd434db59317493f55fc761490d 141 Pfam PF01047 MarR family 32 89 1.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_21440 3fad2dd434db59317493f55fc761490d 141 SMART SM00347 25 125 1.8E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_18075 20b674a7ad881f454a0a36f1746941c0 259 PIRSF PIRSF006648 1 259 1.3E-65 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_18075 20b674a7ad881f454a0a36f1746941c0 259 Pfam PF01061 ABC-2 type transporter 8 215 4.4E-24 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_30415 99547928eaf465109b07ee29d7bcc4fe 204 Gene3D G3DSA:3.40.50.150 12 200 6.3E-25 T 12-10-2018 AFR_30415 99547928eaf465109b07ee29d7bcc4fe 204 Pfam PF08241 Methyltransferase domain 27 116 9.7E-13 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_30415 99547928eaf465109b07ee29d7bcc4fe 204 SUPERFAMILY SSF53335 16 196 8.75E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_39190 d892eaf089be3e9e4841319e09f0eb4b 406 Pfam PF02646 RmuC family 88 374 4.1E-92 T 12-10-2018 IPR003798 DNA recombination RmuC AFR_37390 5cf03d117463ef107ce66c8e5132da8b 320 SUPERFAMILY SSF55821 4 201 3.05E-56 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFR_37390 5cf03d117463ef107ce66c8e5132da8b 320 PIRSF PIRSF004930 2 320 9.7E-97 T 12-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 AFR_37390 5cf03d117463ef107ce66c8e5132da8b 320 Gene3D G3DSA:3.40.50.11030 208 320 1.7E-19 T 12-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily AFR_37390 5cf03d117463ef107ce66c8e5132da8b 320 Gene3D G3DSA:3.90.870.10 1 206 1.3E-70 T 12-10-2018 AFR_37390 5cf03d117463ef107ce66c8e5132da8b 320 Pfam PF01300 Telomere recombination 17 190 1.9E-49 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFR_37390 5cf03d117463ef107ce66c8e5132da8b 320 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 5 192 3.2E-50 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFR_37390 5cf03d117463ef107ce66c8e5132da8b 320 Pfam PF03481 Putative GTP-binding controlling metal-binding 212 319 1.4E-21 T 12-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain AFR_28885 59b1de2c88689d9e6ee0b673ca4e3f31 102 Pfam PF14542 GCN5-related N-acetyl-transferase 13 92 8.6E-26 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase AFR_28885 59b1de2c88689d9e6ee0b673ca4e3f31 102 Gene3D G3DSA:3.40.630.30 5 101 7.4E-27 T 12-10-2018 AFR_28885 59b1de2c88689d9e6ee0b673ca4e3f31 102 SUPERFAMILY SSF55729 3 94 7.89E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_35220 3c964fbe339211d8cea28f4c27434015 397 Pfam PF10935 Protein of unknown function (DUF2637) 69 124 1.9E-8 T 12-10-2018 IPR021235 Protein of unknown function DUF2637 AFR_40450 e4432b23264bc1f44e0f5cb4f751994a 435 Gene3D G3DSA:3.40.50.12240 16 435 2.7E-139 T 12-10-2018 AFR_40450 e4432b23264bc1f44e0f5cb4f751994a 435 SMART SM00382 155 336 5.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_40450 e4432b23264bc1f44e0f5cb4f751994a 435 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 20 432 8.4E-159 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_40450 e4432b23264bc1f44e0f5cb4f751994a 435 SUPERFAMILY SSF52540 91 357 3.7E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40450 e4432b23264bc1f44e0f5cb4f751994a 435 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 143 352 8.4E-75 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFR_22145 aeeb767302450219b5446988b4d3af90 189 Gene3D G3DSA:1.10.357.10 2 185 1.5E-46 T 12-10-2018 AFR_22145 aeeb767302450219b5446988b4d3af90 189 Pfam PF13305 WHG domain 82 161 6.6E-14 T 12-10-2018 IPR025996 WHG domain AFR_22145 aeeb767302450219b5446988b4d3af90 189 SUPERFAMILY SSF46689 3 69 4.82E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_22145 aeeb767302450219b5446988b4d3af90 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22145 aeeb767302450219b5446988b4d3af90 189 SUPERFAMILY SSF48498 74 171 1.34E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_37415 369508763ce3c9ca440e354479eacb7a 449 SUPERFAMILY SSF50998 55 335 3.3E-15 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_37415 369508763ce3c9ca440e354479eacb7a 449 Gene3D G3DSA:2.130.10.10 47 448 2.1E-20 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_37415 369508763ce3c9ca440e354479eacb7a 449 Pfam PF13360 PQQ-like domain 282 381 6.7E-5 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_37415 369508763ce3c9ca440e354479eacb7a 449 Pfam PF13360 PQQ-like domain 87 258 4.6E-8 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_24375 a0f3b0837044cc87bbadf96722a4ffeb 306 SUPERFAMILY SSF53850 92 299 1.47E-33 T 12-10-2018 AFR_24375 a0f3b0837044cc87bbadf96722a4ffeb 306 SUPERFAMILY SSF46785 4 112 1.47E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24375 a0f3b0837044cc87bbadf96722a4ffeb 306 Gene3D G3DSA:3.40.190.10 170 270 2.7E-41 T 12-10-2018 AFR_24375 a0f3b0837044cc87bbadf96722a4ffeb 306 Pfam PF03466 LysR substrate binding domain 92 292 2.7E-36 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_24375 a0f3b0837044cc87bbadf96722a4ffeb 306 Gene3D G3DSA:1.10.10.10 3 90 1.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24375 a0f3b0837044cc87bbadf96722a4ffeb 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.8E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_24375 a0f3b0837044cc87bbadf96722a4ffeb 306 Gene3D G3DSA:3.40.190.10 95 278 2.7E-41 T 12-10-2018 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 Pfam PF06827 Zinc finger found in FPG and IleRS 231 258 3.0E-8 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 Gene3D G3DSA:3.20.190.10 2 106 6.8E-11 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_37855 036820b3f8e2a84685927e05dad1a848 263 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 113 197 8.4E-17 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 SMART SM00898 1 99 9.8E-8 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 ProSitePatterns PS01242 Zinc finger FPG-type signature. 234 258 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 Gene3D G3DSA:1.10.8.50 115 259 7.6E-36 T 12-10-2018 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 SUPERFAMILY SSF46946 112 194 4.27E-19 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 SUPERFAMILY SSF81624 4 114 4.58E-19 T 12-10-2018 IPR035937 MutM-like, N-terminal AFR_37855 036820b3f8e2a84685927e05dad1a848 263 SUPERFAMILY SSF57716 214 258 1.66E-14 T 12-10-2018 AFR_37855 036820b3f8e2a84685927e05dad1a848 263 SMART SM01232 113 205 1.1E-21 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 87 103 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 Gene3D G3DSA:2.60.40.290 333 437 3.1E-31 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 SUPERFAMILY SSF51989 20 302 5.36E-85 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 401 414 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 Pfam PF01341 Glycosyl hydrolases family 6 28 284 6.2E-62 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 Gene3D G3DSA:3.20.20.40 17 303 1.4E-102 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 SMART SM00637 338 437 5.0E-37 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 Pfam PF00553 Cellulose binding domain 338 437 3.2E-24 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 SUPERFAMILY SSF49384 332 437 7.67E-27 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 245 265 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 269 283 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 82 95 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 198 208 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 167 180 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 230 243 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 39 58 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PRINTS PR00733 Glycosyl hydrolase family 6 signature 110 125 1.7E-41 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PIRSF PIRSF001100 3 307 6.7E-79 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_26010 dee38baaa4adf2b0b5b59650cc280f61 437 PIRSF PIRSF001100 318 435 1.4 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 AFR_04790 d41de1e4e79d3d184440368597afcee1 189 Pfam PF00380 Ribosomal protein S9/S16 69 189 7.2E-42 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 AFR_04790 d41de1e4e79d3d184440368597afcee1 189 ProSitePatterns PS00360 Ribosomal protein S9 signature. 128 146 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 AFR_04790 d41de1e4e79d3d184440368597afcee1 189 Gene3D G3DSA:3.30.230.10 64 189 2.5E-47 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_04790 d41de1e4e79d3d184440368597afcee1 189 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 60 189 32.236 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid AFR_04790 d41de1e4e79d3d184440368597afcee1 189 SUPERFAMILY SSF54211 65 189 1.9E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_41570 208b5df275c77ed690fa5438f68241d4 476 PIRSF PIRSF017804 1 476 7.6E-105 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD AFR_41570 208b5df275c77ed690fa5438f68241d4 476 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 2 77 4.0E-21 T 12-10-2018 IPR024962 YukD-like AFR_41570 208b5df275c77ed690fa5438f68241d4 476 Gene3D G3DSA:3.10.20.90 1 79 1.9E-8 T 12-10-2018 AFR_41570 208b5df275c77ed690fa5438f68241d4 476 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 4 471 8.8E-61 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD AFR_15930 8400a6e1889cb8630637096c7cb29e97 1250 Pfam PF13313 Domain of unknown function (DUF4082) 1102 1241 2.5E-48 T 12-10-2018 IPR025141 Domain of unknown function DUF4082 AFR_15930 8400a6e1889cb8630637096c7cb29e97 1250 Pfam PF13313 Domain of unknown function (DUF4082) 663 809 1.9E-50 T 12-10-2018 IPR025141 Domain of unknown function DUF4082 AFR_15930 8400a6e1889cb8630637096c7cb29e97 1250 Pfam PF13313 Domain of unknown function (DUF4082) 931 1073 3.3E-47 T 12-10-2018 IPR025141 Domain of unknown function DUF4082 AFR_15930 8400a6e1889cb8630637096c7cb29e97 1250 SUPERFAMILY SSF81296 564 646 2.17E-12 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_15930 8400a6e1889cb8630637096c7cb29e97 1250 Pfam PF13205 Bacterial Ig-like domain 817 917 2.9E-16 T 12-10-2018 IPR032812 SbsA, Ig-like domain AFR_15930 8400a6e1889cb8630637096c7cb29e97 1250 Gene3D G3DSA:2.60.40.650 565 659 5.0E-10 T 12-10-2018 AFR_11220 ecd1c087a41277b81183606fbe418452 401 Gene3D G3DSA:1.20.1250.20 210 399 1.3E-13 T 12-10-2018 AFR_11220 ecd1c087a41277b81183606fbe418452 401 Pfam PF07690 Major Facilitator Superfamily 242 398 2.3E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_11220 ecd1c087a41277b81183606fbe418452 401 SUPERFAMILY SSF103473 9 397 6.02E-36 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_11220 ecd1c087a41277b81183606fbe418452 401 Gene3D G3DSA:1.20.1250.20 16 201 2.2E-13 T 12-10-2018 AFR_19460 231bd3dbacb65a2a96a8d719da9ba15a 404 Pfam PF00144 Beta-lactamase 50 385 5.8E-40 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_19460 231bd3dbacb65a2a96a8d719da9ba15a 404 SUPERFAMILY SSF56601 48 392 1.63E-54 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_19460 231bd3dbacb65a2a96a8d719da9ba15a 404 Gene3D G3DSA:3.40.710.10 47 388 2.9E-58 T 12-10-2018 AFR_18850 fa9f2d16a1fa89df75f25ee9ce838689 376 PIRSF PIRSF037238 1 371 1.8E-124 T 12-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase AFR_18850 fa9f2d16a1fa89df75f25ee9ce838689 376 SUPERFAMILY SSF55031 177 268 2.49E-20 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFR_18850 fa9f2d16a1fa89df75f25ee9ce838689 376 Gene3D G3DSA:3.30.70.360 177 284 1.6E-98 T 12-10-2018 AFR_18850 fa9f2d16a1fa89df75f25ee9ce838689 376 SUPERFAMILY SSF53187 3 370 5.47E-42 T 12-10-2018 AFR_18850 fa9f2d16a1fa89df75f25ee9ce838689 376 Pfam PF01546 Peptidase family M20/M25/M40 77 368 2.4E-23 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_18850 fa9f2d16a1fa89df75f25ee9ce838689 376 Gene3D G3DSA:3.40.630.10 17 359 1.6E-98 T 12-10-2018 AFR_18850 fa9f2d16a1fa89df75f25ee9ce838689 376 Pfam PF07687 Peptidase dimerisation domain 174 265 4.7E-16 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFR_25130 1ddc5fc00ee796ebca2136df473eb3e9 401 Pfam PF00487 Fatty acid desaturase 72 342 1.2E-29 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 AFR_02615 f26be89c4cd826f0a43857680cc04c5d 160 SUPERFAMILY SSF48498 69 156 2.89E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_02615 f26be89c4cd826f0a43857680cc04c5d 160 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 2.7E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02615 f26be89c4cd826f0a43857680cc04c5d 160 Gene3D G3DSA:1.10.357.10 1 158 6.6E-51 T 12-10-2018 AFR_02615 f26be89c4cd826f0a43857680cc04c5d 160 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 6.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02615 f26be89c4cd826f0a43857680cc04c5d 160 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 6.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_02615 f26be89c4cd826f0a43857680cc04c5d 160 SUPERFAMILY SSF46689 2 65 3.44E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37770 dc9ea9ddd973644350220de5c2e55897 165 Pfam PF08281 Sigma-70, region 4 98 151 3.8E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_37770 dc9ea9ddd973644350220de5c2e55897 165 Pfam PF04542 Sigma-70 region 2 8 72 1.7E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_37770 dc9ea9ddd973644350220de5c2e55897 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 155 3.1E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_37770 dc9ea9ddd973644350220de5c2e55897 165 SUPERFAMILY SSF88659 95 155 3.36E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_37770 dc9ea9ddd973644350220de5c2e55897 165 SUPERFAMILY SSF88946 3 81 9.81E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_37770 dc9ea9ddd973644350220de5c2e55897 165 Gene3D G3DSA:1.10.1740.10 1 75 2.2E-10 T 12-10-2018 AFR_37770 dc9ea9ddd973644350220de5c2e55897 165 Gene3D G3DSA:1.10.10.10 91 157 3.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24290 99e6a8d01509f9f5ee21382bc79929cb 392 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 202 390 5.3E-41 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_24290 99e6a8d01509f9f5ee21382bc79929cb 392 SMART SM00331 174 391 4.3E-29 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_24290 99e6a8d01509f9f5ee21382bc79929cb 392 SUPERFAMILY SSF81606 188 390 3.4E-13 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_24290 99e6a8d01509f9f5ee21382bc79929cb 392 Gene3D G3DSA:3.60.40.10 172 392 4.5E-48 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_18230 1d7066decd282d4f4fee31af022d5541 446 Pfam PF13416 Bacterial extracellular solute-binding protein 76 350 1.8E-17 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_18230 1d7066decd282d4f4fee31af022d5541 446 SUPERFAMILY SSF53850 45 427 6.73E-38 T 12-10-2018 AFR_18230 1d7066decd282d4f4fee31af022d5541 446 Gene3D G3DSA:3.40.190.10 43 430 1.7E-32 T 12-10-2018 AFR_34455 cf9765b83fd9daa34efc92eb7ac6382c 274 Gene3D G3DSA:1.10.1660.10 6 274 3.8E-27 T 12-10-2018 AFR_34455 cf9765b83fd9daa34efc92eb7ac6382c 274 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 1.1E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34455 cf9765b83fd9daa34efc92eb7ac6382c 274 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 1.1E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34455 cf9765b83fd9daa34efc92eb7ac6382c 274 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 1.1E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34455 cf9765b83fd9daa34efc92eb7ac6382c 274 Pfam PF13411 MerR HTH family regulatory protein 5 71 5.5E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34455 cf9765b83fd9daa34efc92eb7ac6382c 274 SMART SM00422 4 73 2.9E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34455 cf9765b83fd9daa34efc92eb7ac6382c 274 SUPERFAMILY SSF46955 5 115 4.76E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_31815 d6304dd751e9d2939291659e37dfc082 379 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 188 377 8.1E-30 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31815 d6304dd751e9d2939291659e37dfc082 379 Gene3D G3DSA:3.60.40.10 163 379 1.3E-35 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31815 d6304dd751e9d2939291659e37dfc082 379 SUPERFAMILY SSF81606 158 321 2.22E-11 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_31815 d6304dd751e9d2939291659e37dfc082 379 SMART SM00331 162 377 1.3E-11 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_26790 df5228ca20cddce8eb1e2d64c0be9fab 342 Pfam PF01339 CheB methylesterase 2 175 5.5E-48 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFR_26790 df5228ca20cddce8eb1e2d64c0be9fab 342 Gene3D G3DSA:3.40.50.180 1 197 5.6E-57 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal AFR_26790 df5228ca20cddce8eb1e2d64c0be9fab 342 SUPERFAMILY SSF52738 1 181 5.75E-52 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal AFR_26790 df5228ca20cddce8eb1e2d64c0be9fab 342 PIRSF PIRSF036461 1 340 7.6E-84 T 12-10-2018 IPR011247 Chemotaxis protein-glutamate methylesterase AFR_33650 9b9e082ac07b636936f1aecc264a1eb2 318 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 10 253 1.2E-65 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain AFR_33650 9b9e082ac07b636936f1aecc264a1eb2 318 Gene3D G3DSA:3.90.920.30 18 291 3.1E-78 T 12-10-2018 AFR_02710 6e402664c9b7a9a6eab7b92b91b5d0dc 345 Pfam PF04443 Acyl-protein synthetase, LuxE 5 343 2.5E-47 T 12-10-2018 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 AFR_02710 6e402664c9b7a9a6eab7b92b91b5d0dc 345 Gene3D G3DSA:3.40.50.12780 2 314 3.3E-13 T 12-10-2018 AFR_02710 6e402664c9b7a9a6eab7b92b91b5d0dc 345 SUPERFAMILY SSF56801 64 311 1.44E-9 T 12-10-2018 AFR_24575 690fffbe3cff81f2cd4971271ccc270a 96 Pfam PF05360 yiaA/B two helix domain 13 65 1.6E-18 T 12-10-2018 IPR008024 YiaAB two helix AFR_00805 1b095c6fb2ae345d67efccc721d9b750 82 SUPERFAMILY SSF103647 19 71 1.19E-6 T 12-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AFR_07275 366fefaaf29cedf335cede5b753b1610 336 SUPERFAMILY SSF53474 7 310 6.29E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_07275 366fefaaf29cedf335cede5b753b1610 336 Pfam PF12146 Serine aminopeptidase, S33 37 243 1.5E-17 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFR_07275 366fefaaf29cedf335cede5b753b1610 336 Gene3D G3DSA:3.40.50.1820 13 312 2.3E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23510 bb23210b5a602de30b0e6af0ba2083bc 534 Pfam PF09362 Domain of unknown function (DUF1996) 83 134 6.2E-5 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_23510 bb23210b5a602de30b0e6af0ba2083bc 534 Pfam PF09362 Domain of unknown function (DUF1996) 365 508 1.6E-17 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_26580 2ea69c76d0f726cc95682a76798dc6b5 298 Pfam PF13560 Helix-turn-helix domain 18 78 8.5E-11 T 12-10-2018 AFR_26580 2ea69c76d0f726cc95682a76798dc6b5 298 SMART SM00530 19 74 1.1E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_26580 2ea69c76d0f726cc95682a76798dc6b5 298 SUPERFAMILY SSF47413 14 69 2.34E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_26580 2ea69c76d0f726cc95682a76798dc6b5 298 Gene3D G3DSA:1.10.260.40 8 82 2.2E-10 T 12-10-2018 AFR_28990 deb3f1d56a855eda74629f83e2dc74da 322 SUPERFAMILY SSF53474 56 321 6.78E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28990 deb3f1d56a855eda74629f83e2dc74da 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 146 159 2.7E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28990 deb3f1d56a855eda74629f83e2dc74da 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 160 173 2.7E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28990 deb3f1d56a855eda74629f83e2dc74da 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 117 2.7E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28990 deb3f1d56a855eda74629f83e2dc74da 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 267 281 2.7E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28990 deb3f1d56a855eda74629f83e2dc74da 322 Pfam PF00561 alpha/beta hydrolase fold 77 309 1.9E-28 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28990 deb3f1d56a855eda74629f83e2dc74da 322 Gene3D G3DSA:3.40.50.1820 57 322 6.2E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33275 52e2b143dccc793a24704baf4bfd3b81 339 Gene3D G3DSA:1.25.40.10 39 326 3.5E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33395 6a0d5d963aaa17fefad482b39b6dda17 174 Gene3D G3DSA:1.10.10.10 1 89 9.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33395 6a0d5d963aaa17fefad482b39b6dda17 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 5.6E-13 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_33395 6a0d5d963aaa17fefad482b39b6dda17 174 SUPERFAMILY SSF46785 4 162 2.9E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20055 05e3028789aa74a5eccaa102e30e1db8 399 Gene3D G3DSA:1.20.1250.20 1 371 1.2E-39 T 12-10-2018 AFR_20055 05e3028789aa74a5eccaa102e30e1db8 399 SUPERFAMILY SSF103473 2 379 3.79E-47 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_20055 05e3028789aa74a5eccaa102e30e1db8 399 Pfam PF07690 Major Facilitator Superfamily 4 236 1.7E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_41200 eba2c59e060c59301675393083c37041 367 Pfam PF13360 PQQ-like domain 86 183 4.8E-7 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_41200 eba2c59e060c59301675393083c37041 367 SUPERFAMILY SSF50998 22 335 6.28E-16 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_41200 eba2c59e060c59301675393083c37041 367 SMART SM00564 290 321 240.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFR_41200 eba2c59e060c59301675393083c37041 367 SMART SM00564 93 130 0.0015 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFR_41200 eba2c59e060c59301675393083c37041 367 Gene3D G3DSA:2.130.10.10 36 363 2.3E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_06500 dda1ec43e6f2dccd28d74355dee097fd 565 Pfam PF05425 Copper resistance protein D 344 441 1.9E-15 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 AFR_06500 dda1ec43e6f2dccd28d74355dee097fd 565 Gene3D G3DSA:2.60.40.1220 48 146 2.7E-20 T 12-10-2018 AFR_06500 dda1ec43e6f2dccd28d74355dee097fd 565 SUPERFAMILY SSF81296 47 142 6.72E-21 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_06500 dda1ec43e6f2dccd28d74355dee097fd 565 Pfam PF04234 CopC domain 48 141 3.2E-22 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 SMART SM00344 7 113 2.4E-33 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 3.1E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 SUPERFAMILY SSF54909 69 142 2.86E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 SUPERFAMILY SSF46785 6 66 1.98E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 Gene3D G3DSA:1.10.10.10 2 58 1.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 Gene3D G3DSA:3.30.70.920 59 141 2.5E-22 T 12-10-2018 AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.3E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.3E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.3E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFR_05810 37511115a2ff51bcb468a06fd23432c7 150 Pfam PF01037 Lrp/AsnC ligand binding domain 80 139 8.8E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 SUPERFAMILY SSF50249 1 66 6.64E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 SMART SM00357 3 67 1.0E-31 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 Gene3D G3DSA:2.40.50.140 1 65 4.7E-30 T 12-10-2018 AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 12-10-2018 IPR019844 Cold-shock conserved site AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 PIRSF PIRSF002599 1 67 4.2E-26 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.2E-31 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 PRINTS PR00050 Cold shock protein signature 40 58 9.2E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 PRINTS PR00050 Cold shock protein signature 25 34 9.2E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_14535 a1ae3bbc35d933624449e4d829ec28d5 67 PRINTS PR00050 Cold shock protein signature 4 19 9.2E-19 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_34600 35ff2e73b0d952b97270f5519fd3aaea 340 Gene3D G3DSA:2.130.10.10 15 136 1.3E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_34600 35ff2e73b0d952b97270f5519fd3aaea 340 SUPERFAMILY SSF110296 18 312 5.23E-33 T 12-10-2018 AFR_34600 35ff2e73b0d952b97270f5519fd3aaea 340 Gene3D G3DSA:2.130.10.10 137 330 4.4E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_34095 be2e7e0086ba9b4cb450c568499ab06e 404 Pfam PF03734 L,D-transpeptidase catalytic domain 243 379 1.4E-14 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_34095 be2e7e0086ba9b4cb450c568499ab06e 404 Gene3D G3DSA:2.60.40.3780 40 135 2.6E-21 T 12-10-2018 AFR_34095 be2e7e0086ba9b4cb450c568499ab06e 404 Gene3D G3DSA:2.40.440.10 241 393 2.2E-82 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_34095 be2e7e0086ba9b4cb450c568499ab06e 404 SUPERFAMILY SSF141523 245 379 6.8E-21 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFR_34095 be2e7e0086ba9b4cb450c568499ab06e 404 Gene3D G3DSA:2.60.40.3710 151 402 2.2E-82 T 12-10-2018 AFR_17905 3255e9184c971c5732984db58014fc08 385 Gene3D G3DSA:3.40.50.2000 199 358 1.2E-32 T 12-10-2018 AFR_17905 3255e9184c971c5732984db58014fc08 385 Pfam PF00534 Glycosyl transferases group 1 203 323 1.5E-21 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_17905 3255e9184c971c5732984db58014fc08 385 SUPERFAMILY SSF53756 2 378 1.83E-55 T 12-10-2018 AFR_17905 3255e9184c971c5732984db58014fc08 385 Pfam PF13439 Glycosyltransferase Family 4 54 192 8.0E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_19875 5beb9d530018223c52e03f193517a632 290 SUPERFAMILY SSF51556 19 289 2.16E-45 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_19875 5beb9d530018223c52e03f193517a632 290 Gene3D G3DSA:3.20.20.140 20 289 3.8E-35 T 12-10-2018 AFR_19875 5beb9d530018223c52e03f193517a632 290 Pfam PF04909 Amidohydrolase 19 289 7.6E-29 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_14955 7512b40f66d35ef36851fa000e27e284 294 Gene3D G3DSA:1.10.3720.10 1 282 6.5E-61 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14955 7512b40f66d35ef36851fa000e27e284 294 SUPERFAMILY SSF161098 8 292 2.09E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14955 7512b40f66d35ef36851fa000e27e284 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 287 3.1E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Gene3D G3DSA:2.60.40.10 25 126 4.2E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_25145 d10556efe4326985ae72912a319d3789 1010 PRINTS PR00014 Fibronectin type III repeat signature 158 168 8.2E-7 T 12-10-2018 AFR_25145 d10556efe4326985ae72912a319d3789 1010 PRINTS PR00014 Fibronectin type III repeat signature 144 153 8.2E-7 T 12-10-2018 AFR_25145 d10556efe4326985ae72912a319d3789 1010 PRINTS PR00014 Fibronectin type III repeat signature 195 209 8.2E-7 T 12-10-2018 AFR_25145 d10556efe4326985ae72912a319d3789 1010 PRINTS PR00014 Fibronectin type III repeat signature 177 195 8.2E-7 T 12-10-2018 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Pfam PF00041 Fibronectin type III domain 136 211 6.4E-16 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Pfam PF00041 Fibronectin type III domain 226 303 9.7E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Pfam PF00041 Fibronectin type III domain 40 117 3.3E-13 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 SUPERFAMILY SSF49265 37 219 1.74E-36 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Gene3D G3DSA:2.60.40.1080 669 754 1.1E-5 T 12-10-2018 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Gene3D G3DSA:2.60.40.10 127 220 3.7E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_25145 d10556efe4326985ae72912a319d3789 1010 SUPERFAMILY SSF49265 218 312 7.78E-18 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 SMART SM00060 224 301 1.0E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 SMART SM00060 131 208 2.1E-12 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 SMART SM00060 38 114 8.9E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Pfam PF02368 Bacterial Ig-like domain (group 2) 670 736 4.7E-6 T 12-10-2018 IPR003343 Bacterial Ig-like, group 2 AFR_25145 d10556efe4326985ae72912a319d3789 1010 Gene3D G3DSA:2.60.40.10 221 312 3.2E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_41180 acf4bf449100ce2dabd58043b5269f9c 397 SUPERFAMILY SSF55874 278 392 2.83E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41180 acf4bf449100ce2dabd58043b5269f9c 397 Gene3D G3DSA:3.30.565.10 272 393 1.2E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41180 acf4bf449100ce2dabd58043b5269f9c 397 SMART SM00387 304 395 3.6E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_41180 acf4bf449100ce2dabd58043b5269f9c 397 Pfam PF07730 Histidine kinase 200 265 5.9E-19 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_27460 4214af44b8a350492b943644fb0c812d 505 Gene3D G3DSA:3.30.420.40 2 257 1.3E-101 T 12-10-2018 AFR_27460 4214af44b8a350492b943644fb0c812d 505 SUPERFAMILY SSF53067 4 259 1.02E-85 T 12-10-2018 AFR_27460 4214af44b8a350492b943644fb0c812d 505 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_27460 4214af44b8a350492b943644fb0c812d 505 Gene3D G3DSA:3.30.420.40 258 505 1.2E-93 T 12-10-2018 AFR_27460 4214af44b8a350492b943644fb0c812d 505 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_27460 4214af44b8a350492b943644fb0c812d 505 SUPERFAMILY SSF53067 259 502 3.97E-83 T 12-10-2018 AFR_27460 4214af44b8a350492b943644fb0c812d 505 PIRSF PIRSF000538 3 505 2.7E-159 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFR_27460 4214af44b8a350492b943644fb0c812d 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 265 455 2.0E-64 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFR_27460 4214af44b8a350492b943644fb0c812d 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 256 7.3E-71 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFR_27460 4214af44b8a350492b943644fb0c812d 505 Hamap MF_00186 Glycerol kinase [glpK]. 2 502 54.648 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFR_27460 4214af44b8a350492b943644fb0c812d 505 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 501 5.5E-224 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFR_02515 a3f247b6b101d9f931a17892d4f6c35c 138 Pfam PF02575 YbaB/EbfC DNA-binding family 13 101 3.5E-11 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_02515 a3f247b6b101d9f931a17892d4f6c35c 138 SUPERFAMILY SSF82607 8 96 5.75E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_02515 a3f247b6b101d9f931a17892d4f6c35c 138 Gene3D G3DSA:3.30.1310.10 7 106 1.2E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_08505 d5f01642e01103cf718e1af053923cdf 569 Pfam PF02734 DAK2 domain 388 563 1.0E-48 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 Gene3D G3DSA:3.40.50.10440 14 188 1.0E-61 T 12-10-2018 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 Pfam PF02733 Dak1 domain 36 332 5.2E-114 T 12-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 Gene3D G3DSA:3.30.1180.20 189 334 2.9E-49 T 12-10-2018 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 SMART SM01120 388 564 1.9E-57 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 SUPERFAMILY SSF101473 363 564 2.09E-52 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 365 563 2.6E-46 T 12-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 Gene3D G3DSA:1.25.40.340 358 567 5.5E-65 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_08505 d5f01642e01103cf718e1af053923cdf 569 SUPERFAMILY SSF82549 4 337 4.45E-111 T 12-10-2018 AFR_13525 49e82a2169de141ffb4f7af5739a4558 190 Pfam PF04542 Sigma-70 region 2 23 87 7.6E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_13525 49e82a2169de141ffb4f7af5739a4558 190 SUPERFAMILY SSF88946 3 95 8.63E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_13525 49e82a2169de141ffb4f7af5739a4558 190 Pfam PF08281 Sigma-70, region 4 118 169 9.1E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_13525 49e82a2169de141ffb4f7af5739a4558 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 171 1.8E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_13525 49e82a2169de141ffb4f7af5739a4558 190 SUPERFAMILY SSF88659 114 171 5.42E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_13525 49e82a2169de141ffb4f7af5739a4558 190 Gene3D G3DSA:1.10.1740.10 1 103 1.5E-17 T 12-10-2018 AFR_13525 49e82a2169de141ffb4f7af5739a4558 190 Gene3D G3DSA:1.10.10.10 104 174 3.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31780 9d485d91730145b82d0780fe8bb07579 400 Gene3D G3DSA:3.30.9.50 38 257 4.7E-60 T 12-10-2018 AFR_31780 9d485d91730145b82d0780fe8bb07579 400 SUPERFAMILY SSF51905 1 354 3.25E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_31780 9d485d91730145b82d0780fe8bb07579 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 4.1E-9 T 12-10-2018 AFR_31780 9d485d91730145b82d0780fe8bb07579 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 4.1E-9 T 12-10-2018 AFR_31780 9d485d91730145b82d0780fe8bb07579 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.1E-9 T 12-10-2018 AFR_31780 9d485d91730145b82d0780fe8bb07579 400 Gene3D G3DSA:3.50.50.60 5 327 4.7E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_31780 9d485d91730145b82d0780fe8bb07579 400 Pfam PF01494 FAD binding domain 2 158 1.1E-7 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_33330 4db9094cdd72fc5dbdaa3b7976f94cbd 377 SUPERFAMILY SSF55874 278 372 2.01E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33330 4db9094cdd72fc5dbdaa3b7976f94cbd 377 Pfam PF07730 Histidine kinase 176 239 7.7E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_33330 4db9094cdd72fc5dbdaa3b7976f94cbd 377 Gene3D G3DSA:3.30.565.10 253 372 7.9E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33330 4db9094cdd72fc5dbdaa3b7976f94cbd 377 SMART SM00387 282 375 0.002 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17520 0eb5835e49cd47d3bf0a5dc6ab07c35e 636 Gene3D G3DSA:2.160.20.10 444 622 1.5E-10 T 12-10-2018 IPR012334 Pectin lyase fold AFR_17520 0eb5835e49cd47d3bf0a5dc6ab07c35e 636 SUPERFAMILY SSF51126 342 572 3.45E-5 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_38615 9f20c9d147360808a36c44e965056650 434 SUPERFAMILY SSF109854 4 139 5.49E-21 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_38615 9f20c9d147360808a36c44e965056650 434 SUPERFAMILY SSF56436 169 429 2.45E-79 T 12-10-2018 IPR016187 C-type lectin fold AFR_38615 9f20c9d147360808a36c44e965056650 434 Pfam PF12867 DinB superfamily 12 143 1.2E-25 T 12-10-2018 IPR024775 DinB-like domain AFR_38615 9f20c9d147360808a36c44e965056650 434 Pfam PF03781 Sulfatase-modifying factor enzyme 1 168 427 9.2E-66 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFR_38615 9f20c9d147360808a36c44e965056650 434 Gene3D G3DSA:3.90.1580.10 157 433 1.5E-65 T 12-10-2018 AFR_38615 9f20c9d147360808a36c44e965056650 434 Gene3D G3DSA:1.20.120.450 2 147 5.9E-8 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_38615 9f20c9d147360808a36c44e965056650 434 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 10 426 6.2E-136 T 12-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 AFR_38615 9f20c9d147360808a36c44e965056650 434 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 429 52.195 T 12-10-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 AFR_30355 6d7d435b789d9b6b7611ff44a920f5d8 256 SUPERFAMILY SSF52540 20 237 2.44E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30355 6d7d435b789d9b6b7611ff44a920f5d8 256 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_30355 6d7d435b789d9b6b7611ff44a920f5d8 256 Pfam PF00005 ABC transporter 37 181 1.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_30355 6d7d435b789d9b6b7611ff44a920f5d8 256 SMART SM00382 46 230 2.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_30355 6d7d435b789d9b6b7611ff44a920f5d8 256 Gene3D G3DSA:3.40.50.300 18 250 4.2E-68 T 12-10-2018 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 SMART SM00220 18 287 2.3E-59 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Pfam PF03793 PASTA domain 471 532 2.6E-11 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Pfam PF03793 PASTA domain 404 463 2.3E-5 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Pfam PF03793 PASTA domain 603 657 2.1E-8 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Pfam PF03793 PASTA domain 537 598 1.3E-15 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Gene3D G3DSA:3.30.10.20 602 659 2.3E-8 T 12-10-2018 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Gene3D G3DSA:1.10.510.10 99 297 2.3E-48 T 12-10-2018 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 SUPERFAMILY SSF54184 537 595 2.49E-5 T 12-10-2018 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 SMART SM00740 397 464 0.1 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 SMART SM00740 465 532 2.4E-10 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 SMART SM00740 599 659 9.1E-6 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 SMART SM00740 533 598 2.0E-17 T 12-10-2018 IPR005543 PASTA domain AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Pfam PF00069 Protein kinase domain 21 275 5.0E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 SUPERFAMILY SSF56112 15 285 5.8E-71 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Gene3D G3DSA:3.30.200.20 6 97 7.3E-30 T 12-10-2018 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Gene3D G3DSA:3.30.10.20 470 534 2.1E-15 T 12-10-2018 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Gene3D G3DSA:3.30.10.20 537 600 1.1E-15 T 12-10-2018 AFR_09690 ba7055a692d917c8b5b194aa325f501f 659 Gene3D G3DSA:3.30.10.20 399 467 9.1E-11 T 12-10-2018 AFR_14675 7c745e1a070a36bd5a17774f1b9f0dc2 129 Gene3D G3DSA:2.30.110.10 1 128 2.0E-23 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_14675 7c745e1a070a36bd5a17774f1b9f0dc2 129 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 86 1.6E-8 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_14675 7c745e1a070a36bd5a17774f1b9f0dc2 129 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 126 2.1E-23 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_14675 7c745e1a070a36bd5a17774f1b9f0dc2 129 SUPERFAMILY SSF50475 3 126 1.1E-19 T 12-10-2018 AFR_25650 01d5056a9a54a69fce73de6f40e06bae 394 Gene3D G3DSA:3.30.565.10 258 388 2.4E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25650 01d5056a9a54a69fce73de6f40e06bae 394 SUPERFAMILY SSF55874 270 387 4.97E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25650 01d5056a9a54a69fce73de6f40e06bae 394 SMART SM00387 295 390 0.0011 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_25650 01d5056a9a54a69fce73de6f40e06bae 394 Pfam PF07730 Histidine kinase 179 245 5.1E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_39215 a7ad28e8bb3e462adb5bb2ac14e3b839 67 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 3 47 4.0E-11 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFR_39215 a7ad28e8bb3e462adb5bb2ac14e3b839 67 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 7 67 13.946 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFR_39215 a7ad28e8bb3e462adb5bb2ac14e3b839 67 Pfam PF02609 Exonuclease VII small subunit 8 58 1.5E-18 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFR_39215 a7ad28e8bb3e462adb5bb2ac14e3b839 67 Gene3D G3DSA:1.10.287.1040 2 67 3.3E-16 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 AFR_39215 a7ad28e8bb3e462adb5bb2ac14e3b839 67 SUPERFAMILY SSF116842 3 59 4.71E-18 T 12-10-2018 AFR_39215 a7ad28e8bb3e462adb5bb2ac14e3b839 67 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 7 60 3.9E-21 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFR_39215 a7ad28e8bb3e462adb5bb2ac14e3b839 67 PIRSF PIRSF006488 1 67 3.2E-23 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFR_36185 c83c9bbc18fa66038463446fdb416710 75 Pfam PF10939 Protein of unknown function (DUF2631) 16 53 2.7E-11 T 12-10-2018 IPR024341 Protein of unknown function DUF2631 AFR_30990 21141d18e2906034c5e7424949de9b16 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 277 3.9E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_30990 21141d18e2906034c5e7424949de9b16 293 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 5 290 3.7E-112 T 12-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type AFR_36325 eef4d59ee1037866c7f6fa07411f1c52 85 Gene3D G3DSA:3.30.300.20 14 75 1.2E-6 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFR_36325 eef4d59ee1037866c7f6fa07411f1c52 85 Hamap MF_00088 UPF0109 protein . 11 82 20.609 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 AFR_36325 eef4d59ee1037866c7f6fa07411f1c52 85 SUPERFAMILY SSF54814 25 70 1.37E-8 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFR_36325 eef4d59ee1037866c7f6fa07411f1c52 85 Pfam PF13083 KH domain 14 72 9.6E-18 T 12-10-2018 AFR_33830 1c80ca1832ed3c59f22dccd34926d472 236 Gene3D G3DSA:1.25.40.10 3 233 3.1E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_33830 1c80ca1832ed3c59f22dccd34926d472 236 SUPERFAMILY SSF48452 19 174 2.15E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_39985 ebc43aebf485eab90b62cd0f6faafc61 220 SUPERFAMILY SSF75217 55 215 5.17E-37 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFR_39985 ebc43aebf485eab90b62cd0f6faafc61 220 Pfam PF00588 SpoU rRNA Methylase family 72 208 1.1E-22 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFR_39985 ebc43aebf485eab90b62cd0f6faafc61 220 Gene3D G3DSA:3.40.1280.10 53 217 8.3E-31 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 SUPERFAMILY SSF48179 615 674 1.45E-9 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 Gene3D G3DSA:3.90.226.10 19 316 1.5E-54 T 12-10-2018 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 SUPERFAMILY SSF51735 323 507 3.36E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 326 505 1.1E-55 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 Gene3D G3DSA:3.40.50.720 317 510 2.9E-60 T 12-10-2018 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 SUPERFAMILY SSF52096 26 303 1.22E-40 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 Gene3D G3DSA:1.10.1040.50 591 685 3.1E-11 T 12-10-2018 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 Gene3D G3DSA:1.10.1040.50 511 590 6.1E-13 T 12-10-2018 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 509 588 6.2E-12 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 Pfam PF00378 Enoyl-CoA hydratase/isomerase 41 223 2.9E-21 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_35205 34aec8b2cf6c304e195a90ebc3667795 689 SUPERFAMILY SSF48179 507 588 7.82E-12 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_10810 b28a053cd5951de631a97403efd91f98 189 Pfam PF13302 Acetyltransferase (GNAT) domain 9 153 2.9E-30 T 12-10-2018 IPR000182 GNAT domain AFR_10810 b28a053cd5951de631a97403efd91f98 189 Gene3D G3DSA:3.40.630.30 2 167 1.3E-42 T 12-10-2018 AFR_10810 b28a053cd5951de631a97403efd91f98 189 SUPERFAMILY SSF55729 2 180 4.7E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_06525 875e973b8f295d864f97c9c401b63941 314 SUPERFAMILY SSF56747 10 216 1.63E-26 T 12-10-2018 AFR_06525 875e973b8f295d864f97c9c401b63941 314 SMART SM00943 13 206 6.0E-41 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFR_06525 875e973b8f295d864f97c9c401b63941 314 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 205 9.5E-43 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFR_22120 d83212c023f6476bbbeb3baf81ec0e76 286 SUPERFAMILY SSF55729 85 280 1.2E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_22120 d83212c023f6476bbbeb3baf81ec0e76 286 SUPERFAMILY SSF55729 17 104 1.92E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_22120 d83212c023f6476bbbeb3baf81ec0e76 286 Gene3D G3DSA:3.40.630.30 4 286 1.1E-67 T 12-10-2018 AFR_22120 d83212c023f6476bbbeb3baf81ec0e76 286 Pfam PF00583 Acetyltransferase (GNAT) family 20 97 3.0E-5 T 12-10-2018 IPR000182 GNAT domain AFR_42370 9b9b906642cab5c54ecb866148fec955 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 3.5E-22 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_42370 9b9b906642cab5c54ecb866148fec955 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 3.5E-22 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_42370 9b9b906642cab5c54ecb866148fec955 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 3.5E-22 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_42370 9b9b906642cab5c54ecb866148fec955 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 3.5E-22 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_42370 9b9b906642cab5c54ecb866148fec955 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 3.5E-22 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_42370 9b9b906642cab5c54ecb866148fec955 176 PIRSF PIRSF001467 2 175 5.3E-52 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 AFR_42370 9b9b906642cab5c54ecb866148fec955 176 SUPERFAMILY SSF50891 6 170 2.05E-58 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_42370 9b9b906642cab5c54ecb866148fec955 176 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 170 2.2E-43 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_42370 9b9b906642cab5c54ecb866148fec955 176 Gene3D G3DSA:2.40.100.10 3 172 7.2E-69 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_31175 14c665d77240cb28dbc01d06a6a330b0 229 SMART SM00862 149 225 5.7E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_31175 14c665d77240cb28dbc01d06a6a330b0 229 Gene3D G3DSA:1.10.10.10 130 229 2.5E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_31175 14c665d77240cb28dbc01d06a6a330b0 229 SUPERFAMILY SSF52172 1 182 6.8E-36 T 12-10-2018 IPR011006 CheY-like superfamily AFR_31175 14c665d77240cb28dbc01d06a6a330b0 229 Gene3D G3DSA:3.40.50.2300 1 129 1.2E-31 T 12-10-2018 AFR_31175 14c665d77240cb28dbc01d06a6a330b0 229 Pfam PF00072 Response regulator receiver domain 4 112 5.3E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_31175 14c665d77240cb28dbc01d06a6a330b0 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 1.1E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_31175 14c665d77240cb28dbc01d06a6a330b0 229 SMART SM00448 2 112 1.6E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 Gene3D G3DSA:3.40.50.1000 87 182 9.7E-78 T 12-10-2018 IPR023214 HAD superfamily AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 SUPERFAMILY SSF56784 7 256 1.21E-67 T 12-10-2018 IPR036412 HAD-like superfamily AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 PIRSF PIRSF000915 3 118 5.5E-25 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 PIRSF PIRSF000915 109 259 5.7E-31 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 3.7E-46 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 Pfam PF13242 HAD-hyrolase-like 182 255 1.8E-22 T 12-10-2018 AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 2.0E-26 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFR_11060 7c3d144a872110b2dd0770da35d9ec01 259 Gene3D G3DSA:3.40.50.1000 10 245 9.7E-78 T 12-10-2018 IPR023214 HAD superfamily AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 13 84 6.0E-30 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 Pfam PF00366 Ribosomal protein S17 18 85 8.7E-31 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 SUPERFAMILY SSF50249 13 90 4.28E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 PRINTS PR00973 Ribosomal protein S17 family signature 32 55 8.6E-12 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 PRINTS PR00973 Ribosomal protein S17 family signature 64 74 8.6E-12 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 PRINTS PR00973 Ribosomal protein S17 family signature 74 81 8.6E-12 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 13 84 7.5E-35 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 Gene3D G3DSA:2.40.50.140 12 91 1.7E-33 T 12-10-2018 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 13 88 25.009 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04550 126189093e04b62f9b1f80b6d8e27209 91 ProSitePatterns PS00056 Ribosomal protein S17 signature. 64 76 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_14850 f1879f09c04d94b8ce384dd004393be7 274 Pfam PF13560 Helix-turn-helix domain 5 84 6.5E-16 T 12-10-2018 AFR_14850 f1879f09c04d94b8ce384dd004393be7 274 SUPERFAMILY SSF47413 29 80 2.5E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_14850 f1879f09c04d94b8ce384dd004393be7 274 SMART SM00530 9 81 9.2E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_14850 f1879f09c04d94b8ce384dd004393be7 274 Gene3D G3DSA:1.10.260.40 24 81 4.0E-7 T 12-10-2018 AFR_11640 da15783dfdab8655d474d680401a766e 136 Pfam PF03795 YCII-related domain 3 112 2.1E-15 T 12-10-2018 IPR005545 YCII-related AFR_11640 da15783dfdab8655d474d680401a766e 136 SUPERFAMILY SSF54909 3 112 5.9E-29 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_11640 da15783dfdab8655d474d680401a766e 136 Gene3D G3DSA:3.30.70.1060 1 116 1.8E-30 T 12-10-2018 AFR_17055 1c2454e107263e82be1ff87e36f4e125 377 Gene3D G3DSA:3.50.50.60 6 328 6.1E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17055 1c2454e107263e82be1ff87e36f4e125 377 Pfam PF01494 FAD binding domain 5 164 1.7E-12 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_17055 1c2454e107263e82be1ff87e36f4e125 377 SUPERFAMILY SSF51905 2 360 1.17E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17055 1c2454e107263e82be1ff87e36f4e125 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 6.7E-11 T 12-10-2018 AFR_17055 1c2454e107263e82be1ff87e36f4e125 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 6.7E-11 T 12-10-2018 AFR_17055 1c2454e107263e82be1ff87e36f4e125 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 6.7E-11 T 12-10-2018 AFR_17055 1c2454e107263e82be1ff87e36f4e125 377 Gene3D G3DSA:3.30.9.50 39 260 6.1E-59 T 12-10-2018 AFR_39445 f0821bf1f6920bab16c8269293f324e6 211 SUPERFAMILY SSF56281 4 182 2.49E-21 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_39445 f0821bf1f6920bab16c8269293f324e6 211 Pfam PF13483 Beta-lactamase superfamily domain 2 173 2.7E-19 T 12-10-2018 AFR_39445 f0821bf1f6920bab16c8269293f324e6 211 Gene3D G3DSA:3.60.15.10 1 191 1.0E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_39445 f0821bf1f6920bab16c8269293f324e6 211 SMART SM00849 7 177 4.9E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_36110 fb107212c354fe6b610e8f1b46580613 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 3.8E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36110 fb107212c354fe6b610e8f1b46580613 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 4.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36110 fb107212c354fe6b610e8f1b46580613 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 4.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36110 fb107212c354fe6b610e8f1b46580613 194 SUPERFAMILY SSF46689 4 82 2.31E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_36110 fb107212c354fe6b610e8f1b46580613 194 SUPERFAMILY SSF48498 81 191 1.34E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_36110 fb107212c354fe6b610e8f1b46580613 194 Gene3D G3DSA:1.10.357.10 56 194 8.4E-23 T 12-10-2018 AFR_36110 fb107212c354fe6b610e8f1b46580613 194 Gene3D G3DSA:1.10.10.60 2 55 2.3E-19 T 12-10-2018 AFR_11985 e2850505fe74d1c5ae293a1d1b6f17b2 278 SUPERFAMILY SSF53474 6 273 1.99E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11985 e2850505fe74d1c5ae293a1d1b6f17b2 278 Gene3D G3DSA:3.40.50.1820 2 273 3.3E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11985 e2850505fe74d1c5ae293a1d1b6f17b2 278 PRINTS PR00412 Epoxide hydrolase signature 27 45 3.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11985 e2850505fe74d1c5ae293a1d1b6f17b2 278 PRINTS PR00412 Epoxide hydrolase signature 248 270 3.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11985 e2850505fe74d1c5ae293a1d1b6f17b2 278 PRINTS PR00412 Epoxide hydrolase signature 104 117 3.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11985 e2850505fe74d1c5ae293a1d1b6f17b2 278 PRINTS PR00412 Epoxide hydrolase signature 47 62 3.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_11985 e2850505fe74d1c5ae293a1d1b6f17b2 278 Pfam PF12697 Alpha/beta hydrolase family 23 265 8.9E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_25705 29dcacc656b221f461fdc3896813569b 209 SUPERFAMILY SSF55729 13 191 1.01E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_25705 29dcacc656b221f461fdc3896813569b 209 Gene3D G3DSA:3.40.630.30 1 209 1.2E-39 T 12-10-2018 AFR_25705 29dcacc656b221f461fdc3896813569b 209 Pfam PF13302 Acetyltransferase (GNAT) domain 16 161 4.4E-11 T 12-10-2018 IPR000182 GNAT domain AFR_38090 aaac66e1168076c5b7a0fa1e9e83150c 230 SUPERFAMILY SSF48371 121 211 4.61E-5 T 12-10-2018 IPR016024 Armadillo-type fold AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 267 2.6E-60 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 SUPERFAMILY SSF63829 10 297 1.08E-51 T 12-10-2018 AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 Gene3D G3DSA:2.120.10.30 4 301 8.8E-80 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 105 126 2.3E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 2.3E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 168 188 2.3E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 248 266 2.3E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 145 167 2.3E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_10715 c1df9691c675ce759ae81a1f0befe458 307 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 206 223 2.3E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_39640 374d017943896f5a42e6a130c52ecec5 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 151 3.4E-10 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_39640 374d017943896f5a42e6a130c52ecec5 159 SUPERFAMILY SSF55961 8 156 3.06E-39 T 12-10-2018 AFR_39640 374d017943896f5a42e6a130c52ecec5 159 Gene3D G3DSA:3.30.530.20 5 158 1.4E-40 T 12-10-2018 IPR023393 START-like domain superfamily AFR_36660 23db295d994036f4ccfa2b08c5d6817b 223 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 7 199 3.8E-46 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AFR_36660 23db295d994036f4ccfa2b08c5d6817b 223 Gene3D G3DSA:3.90.550.10 3 173 4.1E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_36660 23db295d994036f4ccfa2b08c5d6817b 223 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 6 206 21.962 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AFR_36660 23db295d994036f4ccfa2b08c5d6817b 223 Pfam PF01983 Guanylyl transferase CofC like 8 209 3.3E-12 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AFR_36660 23db295d994036f4ccfa2b08c5d6817b 223 SUPERFAMILY SSF53448 6 206 1.38E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_09610 631ae49800804de1ae7afbda3d13288d 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 78 8.3E-12 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_09610 631ae49800804de1ae7afbda3d13288d 293 Gene3D G3DSA:3.40.50.720 2 292 1.4E-36 T 12-10-2018 AFR_09610 631ae49800804de1ae7afbda3d13288d 293 SUPERFAMILY SSF51735 1 282 6.1E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_28615 29fb22572c0cc4166c13c8743c042315 582 Gene3D G3DSA:1.20.1480.50 279 362 9.5E-6 T 12-10-2018 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 Gene3D G3DSA:1.10.287.130 364 423 3.9E-9 T 12-10-2018 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 SUPERFAMILY SSF47384 342 424 1.12E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 SMART SM00387 468 580 5.2E-39 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28615 29fb22572c0cc4166c13c8743c042315 582 Pfam PF00672 HAMP domain 309 352 6.9E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 Pfam PF00512 His Kinase A (phospho-acceptor) domain 360 423 8.2E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 SUPERFAMILY SSF55874 412 578 1.57E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28615 29fb22572c0cc4166c13c8743c042315 582 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 578 5.7E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28615 29fb22572c0cc4166c13c8743c042315 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 1.0E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 1.0E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 577 1.0E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 558 1.0E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 Gene3D G3DSA:3.30.565.10 424 579 2.0E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28615 29fb22572c0cc4166c13c8743c042315 582 SMART SM00304 308 358 0.009 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_28615 29fb22572c0cc4166c13c8743c042315 582 SMART SM00388 359 423 1.2E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_06845 eed14db776baaf2fc71a6eb704b33c84 161 Pfam PF00583 Acetyltransferase (GNAT) family 29 134 4.4E-17 T 12-10-2018 IPR000182 GNAT domain AFR_06845 eed14db776baaf2fc71a6eb704b33c84 161 SUPERFAMILY SSF55729 1 161 1.72E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_06845 eed14db776baaf2fc71a6eb704b33c84 161 Gene3D G3DSA:3.40.630.30 1 161 1.7E-43 T 12-10-2018 AFR_39750 a95787f3bf95408e6e573f5645905d72 254 SUPERFAMILY SSF53474 3 250 6.22E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_39750 a95787f3bf95408e6e573f5645905d72 254 Gene3D G3DSA:3.40.50.1820 1 251 5.6E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_39750 a95787f3bf95408e6e573f5645905d72 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 5.2E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_39750 a95787f3bf95408e6e573f5645905d72 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 5.2E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_39750 a95787f3bf95408e6e573f5645905d72 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.2E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_39750 a95787f3bf95408e6e573f5645905d72 254 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 26 34 1.3E-5 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_39750 a95787f3bf95408e6e573f5645905d72 254 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 97 111 1.3E-5 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_39750 a95787f3bf95408e6e573f5645905d72 254 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 55 66 1.3E-5 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFR_39750 a95787f3bf95408e6e573f5645905d72 254 Pfam PF00561 alpha/beta hydrolase fold 25 133 1.1E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13665 853af6290172c63e72ab1ef03f2ab92c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 5.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13665 853af6290172c63e72ab1ef03f2ab92c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13665 853af6290172c63e72ab1ef03f2ab92c 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 3.8E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13665 853af6290172c63e72ab1ef03f2ab92c 198 SUPERFAMILY SSF48498 87 197 6.88E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13665 853af6290172c63e72ab1ef03f2ab92c 198 SUPERFAMILY SSF46689 7 75 5.99E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13665 853af6290172c63e72ab1ef03f2ab92c 198 Gene3D G3DSA:1.10.357.10 8 198 4.3E-36 T 12-10-2018 AFR_36040 a111bd3f27737de968bd8002ffada59c 231 Pfam PF07722 Peptidase C26 6 214 3.3E-57 T 12-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 AFR_36040 a111bd3f27737de968bd8002ffada59c 231 Gene3D G3DSA:3.40.50.880 3 231 2.2E-68 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_36040 a111bd3f27737de968bd8002ffada59c 231 SUPERFAMILY SSF52317 30 229 3.52E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_01265 7702480004bb4573d4fdea5fb74c87b6 207 Gene3D G3DSA:3.40.430.10 4 189 1.0E-39 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_01265 7702480004bb4573d4fdea5fb74c87b6 207 SUPERFAMILY SSF53597 6 183 1.15E-28 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_01265 7702480004bb4573d4fdea5fb74c87b6 207 Pfam PF01872 RibD C-terminal domain 9 173 2.7E-12 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_02980 914416f54d7a9425602220928f85bd2a 90 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.3E-16 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFR_02980 914416f54d7a9425602220928f85bd2a 90 SUPERFAMILY SSF55594 4 85 2.75E-14 T 12-10-2018 IPR035895 HPr-like superfamily AFR_02980 914416f54d7a9425602220928f85bd2a 90 Gene3D G3DSA:3.30.1340.10 1 83 9.6E-16 T 12-10-2018 IPR035895 HPr-like superfamily AFR_08675 318f090feebf820bba2820aad028fdeb 304 SUPERFAMILY SSF46689 240 290 4.3E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_08675 318f090feebf820bba2820aad028fdeb 304 Gene3D G3DSA:1.10.10.60 183 290 3.7E-25 T 12-10-2018 AFR_08675 318f090feebf820bba2820aad028fdeb 304 SUPERFAMILY SSF46689 188 237 3.05E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_08675 318f090feebf820bba2820aad028fdeb 304 SMART SM00342 204 287 2.4E-29 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_08675 318f090feebf820bba2820aad028fdeb 304 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 241 283 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_08675 318f090feebf820bba2820aad028fdeb 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 287 4.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_08675 318f090feebf820bba2820aad028fdeb 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 256 271 4.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_08675 318f090feebf820bba2820aad028fdeb 304 Pfam PF12833 Helix-turn-helix domain 210 288 7.2E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_08675 318f090feebf820bba2820aad028fdeb 304 Pfam PF12852 Cupin 2 172 3.8E-43 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFR_08185 7295c1705499a7a76a4208d988bd67bc 250 Pfam PF01061 ABC-2 type transporter 6 212 2.9E-13 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_08185 7295c1705499a7a76a4208d988bd67bc 250 PIRSF PIRSF006648 9 249 6.0E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08185 7295c1705499a7a76a4208d988bd67bc 250 PRINTS PR00164 ABC-2 type transport system membrane protein signature 21 42 2.8E-11 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08185 7295c1705499a7a76a4208d988bd67bc 250 PRINTS PR00164 ABC-2 type transport system membrane protein signature 52 74 2.8E-11 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08185 7295c1705499a7a76a4208d988bd67bc 250 PRINTS PR00164 ABC-2 type transport system membrane protein signature 171 190 2.8E-11 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_08185 7295c1705499a7a76a4208d988bd67bc 250 PRINTS PR00164 ABC-2 type transport system membrane protein signature 191 210 2.8E-11 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_17465 8068be44383f7faff7e919c89b384f5f 132 Pfam PF13581 Histidine kinase-like ATPase domain 45 128 2.1E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17465 8068be44383f7faff7e919c89b384f5f 132 SUPERFAMILY SSF55874 45 131 2.63E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17465 8068be44383f7faff7e919c89b384f5f 132 Gene3D G3DSA:3.30.565.10 10 132 1.6E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19640 65d5ce37e3b62a68f03a0705da05a829 333 SUPERFAMILY SSF53901 3 331 3.24E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_19640 65d5ce37e3b62a68f03a0705da05a829 333 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 187 2.1E-22 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_19640 65d5ce37e3b62a68f03a0705da05a829 333 Gene3D G3DSA:3.40.47.10 5 333 6.0E-111 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFR_19640 65d5ce37e3b62a68f03a0705da05a829 333 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 241 330 7.8E-27 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFR_25195 2037b3b1653fc839dc79d6d562090897 248 SUPERFAMILY SSF51556 5 244 1.63E-63 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_25195 2037b3b1653fc839dc79d6d562090897 248 Gene3D G3DSA:3.20.20.140 4 243 2.6E-75 T 12-10-2018 AFR_25195 2037b3b1653fc839dc79d6d562090897 248 Pfam PF04909 Amidohydrolase 6 242 1.3E-41 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_15950 5349ed9f3f3186ff5176416feb8699c2 286 Gene3D G3DSA:3.40.630.30 2 140 7.9E-6 T 12-10-2018 AFR_15950 5349ed9f3f3186ff5176416feb8699c2 286 SUPERFAMILY SSF55729 7 228 4.36E-10 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05420 69a79908394db3fc4874e162f62618e1 364 Gene3D G3DSA:3.40.50.1110 62 261 3.2E-18 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_05420 69a79908394db3fc4874e162f62618e1 364 SUPERFAMILY SSF52266 67 263 1.2E-25 T 12-10-2018 AFR_05420 69a79908394db3fc4874e162f62618e1 364 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 73 249 1.1E-19 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_28825 4779959e9560b77f616cbc252b346e9d 389 SUPERFAMILY SSF55874 299 384 5.11E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28825 4779959e9560b77f616cbc252b346e9d 389 Pfam PF07730 Histidine kinase 192 256 9.6E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_28825 4779959e9560b77f616cbc252b346e9d 389 Gene3D G3DSA:3.30.565.10 268 386 9.5E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28825 4779959e9560b77f616cbc252b346e9d 389 SMART SM00387 300 389 9.0E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03765 5551842a6776f0b236d2034b295cee46 174 SUPERFAMILY SSF48371 1 145 1.41E-7 T 12-10-2018 IPR016024 Armadillo-type fold AFR_03765 5551842a6776f0b236d2034b295cee46 174 Gene3D G3DSA:1.25.10.10 1 173 7.3E-23 T 12-10-2018 IPR011989 Armadillo-like helical AFR_16345 d72828fe9e5d429a8159f84d19d1d808 1118 Pfam PF00905 Penicillin binding protein transpeptidase domain 816 1106 9.4E-29 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_16345 d72828fe9e5d429a8159f84d19d1d808 1118 SUPERFAMILY SSF56601 683 1107 7.63E-45 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_16345 d72828fe9e5d429a8159f84d19d1d808 1118 Pfam PF01098 Cell cycle protein 371 511 2.1E-21 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_16645 4fd5c37a64941c5591e3084d8cb5cb36 269 Pfam PF00005 ABC transporter 21 167 3.0E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_16645 4fd5c37a64941c5591e3084d8cb5cb36 269 SUPERFAMILY SSF52540 3 228 3.43E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16645 4fd5c37a64941c5591e3084d8cb5cb36 269 Gene3D G3DSA:3.40.50.300 2 254 6.7E-60 T 12-10-2018 AFR_16645 4fd5c37a64941c5591e3084d8cb5cb36 269 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_16645 4fd5c37a64941c5591e3084d8cb5cb36 269 SMART SM00382 27 217 3.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_38750 7116f56a67485dd4cac4cf72ac9dc52d 288 Pfam PF00583 Acetyltransferase (GNAT) family 200 272 9.0E-12 T 12-10-2018 IPR000182 GNAT domain AFR_38750 7116f56a67485dd4cac4cf72ac9dc52d 288 Gene3D G3DSA:3.40.630.30 47 286 2.8E-27 T 12-10-2018 AFR_38750 7116f56a67485dd4cac4cf72ac9dc52d 288 SUPERFAMILY SSF55729 35 278 1.19E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_26750 7b28d90d419536cd566b71278f03cce9 207 Gene3D G3DSA:3.40.50.300 8 195 5.6E-16 T 12-10-2018 AFR_29145 a81e2c172058cd77ad6bc059dce46f70 314 SMART SM00829 10 311 8.7E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_29145 a81e2c172058cd77ad6bc059dce46f70 314 Gene3D G3DSA:3.40.50.720 119 277 2.8E-25 T 12-10-2018 AFR_29145 a81e2c172058cd77ad6bc059dce46f70 314 SUPERFAMILY SSF51735 110 285 6.43E-17 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29145 a81e2c172058cd77ad6bc059dce46f70 314 SUPERFAMILY SSF50129 1 147 6.23E-16 T 12-10-2018 IPR011032 GroES-like superfamily AFR_29145 a81e2c172058cd77ad6bc059dce46f70 314 Gene3D G3DSA:3.90.180.10 1 69 1.5E-9 T 12-10-2018 AFR_30140 b0f3b5ce79fd2056764c76ab26773bb3 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 1.4E-15 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_30140 b0f3b5ce79fd2056764c76ab26773bb3 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 1.4E-15 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_30140 b0f3b5ce79fd2056764c76ab26773bb3 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.4E-15 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_30140 b0f3b5ce79fd2056764c76ab26773bb3 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 1.4E-15 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_30140 b0f3b5ce79fd2056764c76ab26773bb3 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 1.4E-15 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_30140 b0f3b5ce79fd2056764c76ab26773bb3 501 Pfam PF00361 Proton-conducting membrane transporter 130 418 5.5E-67 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_11550 c97293fe3deadc42f3f6574e8f1e4b68 404 Pfam PF00155 Aminotransferase class I and II 59 383 2.0E-48 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_11550 c97293fe3deadc42f3f6574e8f1e4b68 404 SUPERFAMILY SSF53383 7 402 1.0E-94 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_11550 c97293fe3deadc42f3f6574e8f1e4b68 404 Gene3D G3DSA:3.40.640.10 53 294 2.8E-135 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_11550 c97293fe3deadc42f3f6574e8f1e4b68 404 Gene3D G3DSA:3.90.1150.10 21 398 2.8E-135 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_01300 a34e2fa5ae0cf0019ce4586725f001c2 182 Gene3D G3DSA:3.40.50.12740 4 179 8.0E-37 T 12-10-2018 AFR_01300 a34e2fa5ae0cf0019ce4586725f001c2 182 SMART SM00448 5 119 1.9E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_01300 a34e2fa5ae0cf0019ce4586725f001c2 182 SUPERFAMILY SSF52172 4 148 1.38E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_01300 a34e2fa5ae0cf0019ce4586725f001c2 182 Pfam PF00072 Response regulator receiver domain 8 119 2.9E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24060 5d54c424dbf2416355ed60dcd982e6cf 217 Gene3D G3DSA:1.10.10.10 124 217 6.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24060 5d54c424dbf2416355ed60dcd982e6cf 217 SUPERFAMILY SSF52172 1 173 1.02E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_24060 5d54c424dbf2416355ed60dcd982e6cf 217 Pfam PF00072 Response regulator receiver domain 3 113 1.2E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24060 5d54c424dbf2416355ed60dcd982e6cf 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 1.9E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_24060 5d54c424dbf2416355ed60dcd982e6cf 217 Gene3D G3DSA:3.40.50.2300 1 123 2.3E-32 T 12-10-2018 AFR_24060 5d54c424dbf2416355ed60dcd982e6cf 217 SMART SM00448 1 112 8.5E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24060 5d54c424dbf2416355ed60dcd982e6cf 217 SMART SM00862 145 217 1.4E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_40590 e19b864739d492e9ed1c52e8152d9b6a 145 Gene3D G3DSA:2.30.30.40 8 132 8.6E-32 T 12-10-2018 AFR_40590 e19b864739d492e9ed1c52e8152d9b6a 145 Gene3D G3DSA:2.40.50.180 24 133 8.6E-32 T 12-10-2018 AFR_40590 e19b864739d492e9ed1c52e8152d9b6a 145 SMART SM00260 1 138 1.0E-29 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_40590 e19b864739d492e9ed1c52e8152d9b6a 145 SUPERFAMILY SSF50341 2 139 6.41E-32 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_40590 e19b864739d492e9ed1c52e8152d9b6a 145 Pfam PF01584 CheW-like domain 5 139 7.7E-29 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_16040 781ac508de783a0e4874fc792f84a55d 290 Pfam PF04321 RmlD substrate binding domain 11 287 3.9E-92 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFR_16040 781ac508de783a0e4874fc792f84a55d 290 SUPERFAMILY SSF51735 11 286 1.65E-81 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16040 781ac508de783a0e4874fc792f84a55d 290 Gene3D G3DSA:3.90.25.10 163 281 2.3E-86 T 12-10-2018 AFR_16040 781ac508de783a0e4874fc792f84a55d 290 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 13 287 5.5E-82 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFR_16040 781ac508de783a0e4874fc792f84a55d 290 Gene3D G3DSA:3.40.50.720 14 276 2.3E-86 T 12-10-2018 AFR_39775 532a315ffc644c4c8c2318a1733e6c03 152 Pfam PF14325 Domain of unknown function (DUF4383) 15 131 1.6E-7 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 163 8.3E-49 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 SUPERFAMILY SSF88946 6 87 1.57E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 Gene3D G3DSA:1.10.1740.10 2 80 5.8E-10 T 12-10-2018 AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 SUPERFAMILY SSF88659 91 162 2.24E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 Pfam PF08281 Sigma-70, region 4 107 158 2.7E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 160 3.0E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 Pfam PF04542 Sigma-70 region 2 17 76 3.7E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_02955 d148c0e856e16bd62d31e11cf6168ceb 176 Gene3D G3DSA:1.10.10.10 88 165 3.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25390 96fba5b8fb7886d566fb4538b4b11895 122 Gene3D G3DSA:3.10.50.40 6 122 6.1E-40 T 12-10-2018 AFR_25390 96fba5b8fb7886d566fb4538b4b11895 122 SUPERFAMILY SSF54534 14 122 5.7E-38 T 12-10-2018 AFR_25390 96fba5b8fb7886d566fb4538b4b11895 122 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 28 119 2.1E-31 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 157 6.4E-43 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 SUPERFAMILY SSF88659 98 156 3.55E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 Gene3D G3DSA:1.10.1740.10 1 80 5.9E-13 T 12-10-2018 AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 151 2.0E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 Pfam PF08281 Sigma-70, region 4 99 151 2.4E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 SUPERFAMILY SSF88946 3 73 2.55E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 Pfam PF04542 Sigma-70 region 2 15 75 7.1E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_36475 2e172e997d51d745d86b9524a7b374f0 170 Gene3D G3DSA:1.10.10.10 92 160 1.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03475 9a088cab8855bcba32b53e2a3accf3c8 134 Pfam PF14534 Domain of unknown function (DUF4440) 2 102 1.9E-10 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 AFR_03475 9a088cab8855bcba32b53e2a3accf3c8 134 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 1 111 2.5E-19 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 AFR_03475 9a088cab8855bcba32b53e2a3accf3c8 134 SUPERFAMILY SSF54427 2 109 8.6E-28 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_03475 9a088cab8855bcba32b53e2a3accf3c8 134 Gene3D G3DSA:3.10.450.50 1 126 1.9E-34 T 12-10-2018 AFR_19880 d76b16cf246748dcb233f0736e2dd03a 514 Gene3D G3DSA:1.20.1720.10 11 218 1.4E-50 T 12-10-2018 AFR_19880 d76b16cf246748dcb233f0736e2dd03a 514 SUPERFAMILY SSF103473 3 493 4.58E-75 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_19880 d76b16cf246748dcb233f0736e2dd03a 514 Pfam PF07690 Major Facilitator Superfamily 14 405 2.6E-53 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_19880 d76b16cf246748dcb233f0736e2dd03a 514 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 415 9.9E-85 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_19880 d76b16cf246748dcb233f0736e2dd03a 514 Gene3D G3DSA:1.20.1250.20 263 497 5.7E-16 T 12-10-2018 AFR_34945 b1966b6265f1845252660593b94e21f5 356 Gene3D G3DSA:3.30.70.260 4 72 3.4E-6 T 12-10-2018 AFR_34945 b1966b6265f1845252660593b94e21f5 356 SUPERFAMILY SSF55021 4 66 8.33E-8 T 12-10-2018 AFR_34945 b1966b6265f1845252660593b94e21f5 356 Pfam PF00583 Acetyltransferase (GNAT) family 248 323 9.2E-8 T 12-10-2018 IPR000182 GNAT domain AFR_34945 b1966b6265f1845252660593b94e21f5 356 SUPERFAMILY SSF55729 169 323 5.67E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_34945 b1966b6265f1845252660593b94e21f5 356 Gene3D G3DSA:3.40.630.30 179 350 1.7E-30 T 12-10-2018 AFR_15050 23f4cb8e92d9115fde4628c0930c9e80 220 SUPERFAMILY SSF52172 1 179 7.12E-35 T 12-10-2018 IPR011006 CheY-like superfamily AFR_15050 23f4cb8e92d9115fde4628c0930c9e80 220 Gene3D G3DSA:1.10.10.10 124 220 1.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15050 23f4cb8e92d9115fde4628c0930c9e80 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 1.1E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_15050 23f4cb8e92d9115fde4628c0930c9e80 220 SMART SM00862 145 217 1.5E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_15050 23f4cb8e92d9115fde4628c0930c9e80 220 Gene3D G3DSA:3.40.50.2300 1 120 7.6E-32 T 12-10-2018 AFR_15050 23f4cb8e92d9115fde4628c0930c9e80 220 SMART SM00448 1 112 1.4E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_15050 23f4cb8e92d9115fde4628c0930c9e80 220 Pfam PF00072 Response regulator receiver domain 3 113 2.1E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_21960 715387ee13debf7b24a52a239662e506 192 Gene3D G3DSA:3.40.50.300 4 176 2.5E-22 T 12-10-2018 AFR_21960 715387ee13debf7b24a52a239662e506 192 SUPERFAMILY SSF52540 14 160 3.5E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04625 75b2ad55e92443dce1addcb00a5bf914 179 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 5.1E-22 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 AFR_37095 b2e87873789dba9f7438c63c9a289f35 392 SUPERFAMILY SSF46785 14 77 4.09E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_37095 b2e87873789dba9f7438c63c9a289f35 392 Gene3D G3DSA:3.30.420.40 81 211 5.8E-24 T 12-10-2018 AFR_37095 b2e87873789dba9f7438c63c9a289f35 392 Pfam PF00480 ROK family 88 359 7.8E-36 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_37095 b2e87873789dba9f7438c63c9a289f35 392 Pfam PF12802 MarR family 18 71 2.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_37095 b2e87873789dba9f7438c63c9a289f35 392 Gene3D G3DSA:1.10.10.10 2 78 3.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37095 b2e87873789dba9f7438c63c9a289f35 392 Gene3D G3DSA:3.30.420.40 212 359 1.6E-26 T 12-10-2018 AFR_37095 b2e87873789dba9f7438c63c9a289f35 392 SUPERFAMILY SSF53067 85 383 3.08E-35 T 12-10-2018 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 Pfam PF00800 Prephenate dehydratase 10 187 1.5E-45 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 227 234 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 SUPERFAMILY SSF53850 8 193 5.26E-44 T 12-10-2018 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 Gene3D G3DSA:3.40.190.10 95 176 5.9E-21 T 12-10-2018 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 Gene3D G3DSA:3.40.190.10 4 94 2.3E-27 T 12-10-2018 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 Gene3D G3DSA:3.30.70.260 189 285 1.7E-29 T 12-10-2018 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 Pfam PF01842 ACT domain 207 264 3.9E-7 T 12-10-2018 IPR002912 ACT domain AFR_42565 03359218202474ccba9b371ffca7e7ea 318 PIRSF PIRSF001500 4 282 3.2E-59 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFR_42565 03359218202474ccba9b371ffca7e7ea 318 SUPERFAMILY SSF55021 184 280 4.58E-23 T 12-10-2018 AFR_34260 614c443d8330dbafad2b0b3684bc7c5f 467 Gene3D G3DSA:3.40.50.880 178 316 6.7E-16 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_34260 614c443d8330dbafad2b0b3684bc7c5f 467 Gene3D G3DSA:3.40.50.880 2 126 3.4E-11 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_34260 614c443d8330dbafad2b0b3684bc7c5f 467 Gene3D G3DSA:1.20.120.640 317 463 1.2E-10 T 12-10-2018 AFR_34260 614c443d8330dbafad2b0b3684bc7c5f 467 SUPERFAMILY SSF47323 407 463 3.53E-11 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_37610 ed9d86ae8eafbec227f154f60f8f3447 121 Gene3D G3DSA:3.10.450.50 1 118 5.8E-13 T 12-10-2018 AFR_37610 ed9d86ae8eafbec227f154f60f8f3447 121 SUPERFAMILY SSF54427 1 115 1.72E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_37610 ed9d86ae8eafbec227f154f60f8f3447 121 Pfam PF12680 SnoaL-like domain 11 94 1.2E-9 T 12-10-2018 IPR037401 SnoaL-like domain AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00359 B-class P450 signature 182 204 6.5E-17 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00359 B-class P450 signature 74 85 6.5E-17 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00359 B-class P450 signature 331 340 6.5E-17 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00359 B-class P450 signature 340 351 6.5E-17 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00359 B-class P450 signature 276 303 6.5E-17 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00359 B-class P450 signature 259 270 6.5E-17 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 SUPERFAMILY SSF48264 25 385 1.07E-51 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00385 P450 superfamily signature 331 340 5.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00385 P450 superfamily signature 340 351 5.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00385 P450 superfamily signature 259 270 5.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 PRINTS PR00385 P450 superfamily signature 223 240 5.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 Gene3D G3DSA:1.10.630.10 12 390 4.8E-61 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 Pfam PF00067 Cytochrome P450 259 358 1.9E-13 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_32715 9abc658980dadbb350813f31f38bca74 390 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_36495 0e9ea311da66279f6f380534b21daabf 245 Pfam PF00188 Cysteine-rich secretory protein family 126 242 3.4E-17 T 12-10-2018 IPR014044 CAP domain AFR_36495 0e9ea311da66279f6f380534b21daabf 245 SUPERFAMILY SSF55797 119 243 2.14E-15 T 12-10-2018 IPR035940 CAP superfamily AFR_36495 0e9ea311da66279f6f380534b21daabf 245 Gene3D G3DSA:3.40.33.10 68 243 1.0E-40 T 12-10-2018 IPR035940 CAP superfamily AFR_34685 a234855cc59c37020a328386a26992fb 294 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 94 116 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_34685 a234855cc59c37020a328386a26992fb 294 Gene3D G3DSA:1.20.120.1760 14 179 1.1E-28 T 12-10-2018 AFR_34685 a234855cc59c37020a328386a26992fb 294 Pfam PF01066 CDP-alcohol phosphatidyltransferase 45 116 3.9E-9 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_38340 a43b434ca60d3de8e4b372a23c1a87cb 448 Pfam PF03109 ABC1 family 112 237 2.8E-27 T 12-10-2018 IPR004147 UbiB domain AFR_38340 a43b434ca60d3de8e4b372a23c1a87cb 448 SUPERFAMILY SSF56112 95 317 2.38E-24 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_38340 a43b434ca60d3de8e4b372a23c1a87cb 448 Pfam PF01636 Phosphotransferase enzyme family 267 311 1.5E-5 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_38920 aca4d8cc62d94e56cdcf79b2e508da15 338 SUPERFAMILY SSF46894 271 338 4.76E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_38920 aca4d8cc62d94e56cdcf79b2e508da15 338 Gene3D G3DSA:1.10.10.10 12 104 1.5E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38920 aca4d8cc62d94e56cdcf79b2e508da15 338 SMART SM00421 275 332 4.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38920 aca4d8cc62d94e56cdcf79b2e508da15 338 Pfam PF00196 Bacterial regulatory proteins, luxR family 278 332 1.5E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_38920 aca4d8cc62d94e56cdcf79b2e508da15 338 Gene3D G3DSA:1.10.10.10 218 337 1.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26140 322a5db549f84621f42e9a011475c798 274 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 171 7.6E-19 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_26140 322a5db549f84621f42e9a011475c798 274 Gene3D G3DSA:3.40.50.720 2 233 4.6E-53 T 12-10-2018 AFR_26140 322a5db549f84621f42e9a011475c798 274 SUPERFAMILY SSF51735 1 223 9.3E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 77 20.482 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 76 2.0E-25 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 74 4.0E-20 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 1.9E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 1.9E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 1.9E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 1.9E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 SUPERFAMILY SSF46911 7 76 1.7E-27 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 Gene3D G3DSA:4.10.640.10 1 79 1.0E-27 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42820 cf04d37041dbd6b3a9bd4c6e462d3680 79 Pfam PF01084 Ribosomal protein S18 22 72 2.0E-24 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_36705 2cb7ebe3ac53518e39a63067e252e896 230 Gene3D G3DSA:3.60.15.10 9 227 3.0E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_36705 2cb7ebe3ac53518e39a63067e252e896 230 Pfam PF00753 Metallo-beta-lactamase superfamily 30 174 9.5E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_36705 2cb7ebe3ac53518e39a63067e252e896 230 SMART SM00849 30 223 2.9E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_36705 2cb7ebe3ac53518e39a63067e252e896 230 SUPERFAMILY SSF56281 24 228 2.3E-32 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_14375 722b72ecc81fc926897fffc8473548f4 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 41 116 2.1E-9 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_14375 722b72ecc81fc926897fffc8473548f4 178 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 57 100 6.5E-12 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_14375 722b72ecc81fc926897fffc8473548f4 178 SUPERFAMILY SSF69118 1 175 1.07E-45 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_14375 722b72ecc81fc926897fffc8473548f4 178 Gene3D G3DSA:1.20.1290.10 15 176 1.1E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 Gene3D G3DSA:3.40.50.720 25 171 3.3E-21 T 12-10-2018 AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 SUPERFAMILY SSF116726 503 578 1.83E-6 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 Gene3D G3DSA:3.40.50.720 349 494 1.8E-28 T 12-10-2018 AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 Pfam PF02254 TrkA-N domain 28 143 3.1E-9 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 Pfam PF02254 TrkA-N domain 362 470 3.7E-18 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 Gene3D G3DSA:3.30.70.1450 499 579 7.7E-6 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 SUPERFAMILY SSF51735 25 163 5.42E-15 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_41055 8cad0c3584087df461772b7ef5c84eb1 594 SUPERFAMILY SSF51735 359 502 1.36E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_18380 ad02a01e7a335dc9026e2ac741f44637 580 Pfam PF00664 ABC transporter transmembrane region 30 298 1.5E-27 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_18380 ad02a01e7a335dc9026e2ac741f44637 580 Gene3D G3DSA:3.40.50.300 335 575 6.3E-62 T 12-10-2018 AFR_18380 ad02a01e7a335dc9026e2ac741f44637 580 Pfam PF00005 ABC transporter 356 500 1.8E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_18380 ad02a01e7a335dc9026e2ac741f44637 580 SUPERFAMILY SSF52540 331 570 4.02E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18380 ad02a01e7a335dc9026e2ac741f44637 580 SMART SM00382 365 546 8.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_18380 ad02a01e7a335dc9026e2ac741f44637 580 Gene3D G3DSA:1.20.1560.10 4 327 4.8E-57 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_18380 ad02a01e7a335dc9026e2ac741f44637 580 SUPERFAMILY SSF90123 14 325 3.01E-57 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_27425 6a390a0a0478b80b690ec58201ab12e2 236 Pfam PF08021 Siderophore-interacting FAD-binding domain 57 111 5.5E-6 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting AFR_27425 6a390a0a0478b80b690ec58201ab12e2 236 Gene3D G3DSA:2.40.30.10 43 113 8.7E-10 T 12-10-2018 AFR_27425 6a390a0a0478b80b690ec58201ab12e2 236 SUPERFAMILY SSF63380 19 114 3.83E-9 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.5E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.152 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 SUPERFAMILY SSF143034 2 63 4.58E-20 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.5E-13 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.5E-13 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.5E-13 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 Pfam PF01632 Ribosomal protein L35 2 62 3.2E-22 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_30460 def06bc4db80c2ff50604238d4dfd452 64 Gene3D G3DSA:2.40.50.530 2 64 1.5E-21 T 12-10-2018 AFR_31540 680214cf652eecdeb398e22d976d537b 120 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 13 120 1.6E-36 T 12-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFR_31540 680214cf652eecdeb398e22d976d537b 120 ProSitePatterns PS00768 Transthyretin signature 1. 18 33 - T 12-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFR_31540 680214cf652eecdeb398e22d976d537b 120 SUPERFAMILY SSF49472 11 120 2.22E-37 T 12-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFR_31540 680214cf652eecdeb398e22d976d537b 120 Pfam PF00576 HIUase/Transthyretin family 15 119 7.1E-34 T 12-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFR_31540 680214cf652eecdeb398e22d976d537b 120 Gene3D G3DSA:2.60.40.180 11 120 2.8E-37 T 12-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFR_14540 fb27cbb1b4aa7c0e6d511d473db5956c 192 Gene3D G3DSA:3.40.430.10 6 187 6.7E-24 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_14540 fb27cbb1b4aa7c0e6d511d473db5956c 192 SUPERFAMILY SSF53597 8 189 1.96E-18 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_14540 fb27cbb1b4aa7c0e6d511d473db5956c 192 Pfam PF01872 RibD C-terminal domain 6 181 7.6E-15 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_24885 0e7ed5f390661b466d9f7513db93886e 266 Gene3D G3DSA:3.90.25.10 118 247 5.7E-56 T 12-10-2018 AFR_24885 0e7ed5f390661b466d9f7513db93886e 266 Gene3D G3DSA:3.40.50.720 3 245 5.7E-56 T 12-10-2018 AFR_24885 0e7ed5f390661b466d9f7513db93886e 266 SUPERFAMILY SSF51735 2 260 8.21E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24885 0e7ed5f390661b466d9f7513db93886e 266 Pfam PF13460 NAD(P)H-binding 6 125 6.1E-16 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_23705 08e992b5515c4501cf49a963b66e524a 167 Gene3D G3DSA:2.60.120.10 20 156 4.1E-25 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_23705 08e992b5515c4501cf49a963b66e524a 167 SUPERFAMILY SSF51182 31 146 8.91E-24 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_23705 08e992b5515c4501cf49a963b66e524a 167 Pfam PF07883 Cupin domain 65 133 1.6E-14 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_41770 eb947ee74eac84a94a40011653365062 524 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 34 167 7.4E-21 T 12-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal AFR_41770 eb947ee74eac84a94a40011653365062 524 Gene3D G3DSA:3.20.20.80 171 510 8.5E-170 T 12-10-2018 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 325 338 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 194 215 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 303 321 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 452 468 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 470 487 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 165 182 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 255 272 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 PRINTS PR00738 Glycosyl hydrolase family 20 signature 123 143 3.6E-46 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AFR_41770 eb947ee74eac84a94a40011653365062 524 SUPERFAMILY SSF55545 28 170 7.59E-29 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_41770 eb947ee74eac84a94a40011653365062 524 Gene3D G3DSA:3.30.379.10 35 170 8.5E-170 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_41770 eb947ee74eac84a94a40011653365062 524 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 171 488 1.7E-80 T 12-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 AFR_41770 eb947ee74eac84a94a40011653365062 524 SUPERFAMILY SSF51445 171 518 5.62E-104 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_40605 e8959723c4044eb6f2b0c08c6b899d6a 235 Gene3D G3DSA:3.30.565.10 80 230 1.0E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40605 e8959723c4044eb6f2b0c08c6b899d6a 235 Pfam PF00512 His Kinase A (phospho-acceptor) domain 17 82 5.6E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_40605 e8959723c4044eb6f2b0c08c6b899d6a 235 SMART SM00388 16 82 1.5E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_40605 e8959723c4044eb6f2b0c08c6b899d6a 235 SUPERFAMILY SSF47384 16 83 7.65E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_40605 e8959723c4044eb6f2b0c08c6b899d6a 235 Gene3D G3DSA:1.10.287.130 20 79 1.0E-16 T 12-10-2018 AFR_05510 646105e5c8f7377391a342da56d0826d 455 Pfam PF01425 Amidase 30 437 2.3E-86 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_05510 646105e5c8f7377391a342da56d0826d 455 SUPERFAMILY SSF75304 7 444 3.01E-107 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_05510 646105e5c8f7377391a342da56d0826d 455 Gene3D G3DSA:3.90.1300.10 6 454 8.3E-115 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 SUPERFAMILY SSF51735 172 370 4.07E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 Gene3D G3DSA:3.90.180.10 42 395 1.4E-129 T 12-10-2018 AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 76 90 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 3 410 1.5E-223 T 12-10-2018 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 1.6E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 Pfam PF00107 Zinc-binding dehydrogenase 206 280 3.0E-7 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 SUPERFAMILY SSF50129 4 195 5.97E-57 T 12-10-2018 IPR011032 GroES-like superfamily AFR_19620 16e2e61a259f7f3ed5f1ac08f92ca471 415 Gene3D G3DSA:3.40.50.720 187 358 1.4E-129 T 12-10-2018 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 SUPERFAMILY SSF50494 21 257 6.56E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_16685 febc64c658dbace34d75d4056f1abff8 261 Pfam PF00089 Trypsin 33 252 3.6E-25 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 Gene3D G3DSA:2.40.10.10 126 259 3.0E-14 T 12-10-2018 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 78 83 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 SMART SM00020 32 252 4.0E-12 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 Gene3D G3DSA:2.40.10.10 33 125 4.5E-11 T 12-10-2018 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 203 215 2.8E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 125 139 2.8E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_16685 febc64c658dbace34d75d4056f1abff8 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 68 83 2.8E-9 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 Gene3D G3DSA:3.20.20.450 581 837 2.0E-88 T 12-10-2018 IPR035919 EAL domain superfamily AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 SUPERFAMILY SSF141868 593 833 1.44E-79 T 12-10-2018 IPR035919 EAL domain superfamily AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 396 562 1.2E-25 T 12-10-2018 IPR000160 GGDEF domain AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 SMART SM00052 580 826 8.9E-98 T 12-10-2018 IPR001633 EAL domain AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 Pfam PF00990 Diguanylate cyclase, GGDEF domain 399 562 5.4E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 Pfam PF00563 EAL domain 587 821 8.1E-69 T 12-10-2018 IPR001633 EAL domain AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 Gene3D G3DSA:3.30.70.270 364 570 6.8E-39 T 12-10-2018 AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 SMART SM00267 386 570 4.0E-33 T 12-10-2018 IPR000160 GGDEF domain AFR_05540 13b2aa39676b589cc6c09958c20cd8da 851 SUPERFAMILY SSF55073 402 563 4.16E-32 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_10285 10a53ea726ed91fb695ea4d76ba6c490 124 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 12 115 31.383 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFR_10285 10a53ea726ed91fb695ea4d76ba6c490 124 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 38 110 1.1E-33 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFR_10285 10a53ea726ed91fb695ea4d76ba6c490 124 Gene3D G3DSA:3.10.20.400 6 102 4.4E-39 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFR_10285 10a53ea726ed91fb695ea4d76ba6c490 124 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 61 110 3.0E-18 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFR_10285 10a53ea726ed91fb695ea4d76ba6c490 124 SUPERFAMILY SSF141734 12 115 2.75E-46 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFR_35430 ce1d761345876101c98746932f172f74 394 PRINTS PR01272 Acetoin utilisation ACUC protein signature 104 117 5.2E-5 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFR_35430 ce1d761345876101c98746932f172f74 394 PRINTS PR01272 Acetoin utilisation ACUC protein signature 83 97 5.2E-5 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFR_35430 ce1d761345876101c98746932f172f74 394 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 5.2E-5 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFR_35430 ce1d761345876101c98746932f172f74 394 Gene3D G3DSA:3.40.800.20 5 342 1.7E-98 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFR_35430 ce1d761345876101c98746932f172f74 394 PRINTS PR01270 Histone deacetylase superfamily signature 160 175 1.3E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFR_35430 ce1d761345876101c98746932f172f74 394 PRINTS PR01270 Histone deacetylase superfamily signature 127 150 1.3E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFR_35430 ce1d761345876101c98746932f172f74 394 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 1.3E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFR_35430 ce1d761345876101c98746932f172f74 394 SUPERFAMILY SSF52768 4 333 6.71E-100 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily AFR_35430 ce1d761345876101c98746932f172f74 394 Pfam PF00850 Histone deacetylase domain 21 316 3.4E-73 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFR_26745 e1c65dafafd067af608a0d6ac4601080 139 SUPERFAMILY SSF57716 103 137 7.13E-8 T 12-10-2018 AFR_26745 e1c65dafafd067af608a0d6ac4601080 139 Gene3D G3DSA:1.20.120.910 8 139 9.4E-27 T 12-10-2018 AFR_26745 e1c65dafafd067af608a0d6ac4601080 139 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 101 135 1.1E-6 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 AFR_26745 e1c65dafafd067af608a0d6ac4601080 139 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 106 130 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site AFR_41680 34423e86a4c83873d0af76df1ed9e4b8 297 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 49 232 1.5E-9 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFR_41680 34423e86a4c83873d0af76df1ed9e4b8 297 SUPERFAMILY SSF56300 45 288 3.48E-26 T 12-10-2018 AFR_41680 34423e86a4c83873d0af76df1ed9e4b8 297 Gene3D G3DSA:3.60.21.10 47 250 8.4E-15 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 Pfam PF00005 ABC transporter 358 507 1.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 Pfam PF00664 ABC transporter transmembrane region 26 293 2.7E-37 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 SUPERFAMILY SSF90123 15 327 1.96E-69 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 Gene3D G3DSA:3.40.50.300 334 579 1.9E-83 T 12-10-2018 AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 SMART SM00382 367 553 2.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 Gene3D G3DSA:1.20.1560.10 2 326 8.9E-75 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_26780 194b1d190bad50ccbcacf25a405fff35 581 SUPERFAMILY SSF52540 338 578 1.67E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18190 838108a6c422209e8dd6788d0086e683 402 Gene3D G3DSA:3.40.710.10 84 372 1.4E-88 T 12-10-2018 AFR_18190 838108a6c422209e8dd6788d0086e683 402 Pfam PF00144 Beta-lactamase 84 381 1.8E-37 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_18190 838108a6c422209e8dd6788d0086e683 402 Gene3D G3DSA:1.20.58.710 137 235 1.4E-88 T 12-10-2018 AFR_18190 838108a6c422209e8dd6788d0086e683 402 SUPERFAMILY SSF56601 29 392 3.38E-78 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_40940 b61ea0efcf123ccde246f0a7cbf22c58 284 Pfam PF12679 ABC-2 family transporter protein 29 282 9.5E-15 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_37170 4a30e91e6c83028443ce5b6daceca7f8 557 Gene3D G3DSA:3.20.20.240 2 557 4.3E-225 T 12-10-2018 AFR_37170 4a30e91e6c83028443ce5b6daceca7f8 557 Pfam PF01642 Methylmalonyl-CoA mutase 28 549 8.9E-212 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_37170 4a30e91e6c83028443ce5b6daceca7f8 557 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 556 4.6E-200 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_37170 4a30e91e6c83028443ce5b6daceca7f8 557 SUPERFAMILY SSF51703 6 551 1.36E-190 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_11720 9f9fe852a00f481e450cea85f047ddbf 258 Gene3D G3DSA:3.20.20.370 47 257 2.6E-42 T 12-10-2018 AFR_11720 9f9fe852a00f481e450cea85f047ddbf 258 SUPERFAMILY SSF88713 65 228 2.22E-31 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_11720 9f9fe852a00f481e450cea85f047ddbf 258 Pfam PF01522 Polysaccharide deacetylase 94 219 3.4E-23 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_41040 0f6163a0a6ebc4370013d8fe7005dd4b 245 SUPERFAMILY SSF48317 14 223 1.83E-20 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_41040 0f6163a0a6ebc4370013d8fe7005dd4b 245 Pfam PF01569 PAP2 superfamily 88 219 4.1E-14 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_41040 0f6163a0a6ebc4370013d8fe7005dd4b 245 Gene3D G3DSA:1.20.144.10 125 224 2.4E-8 T 12-10-2018 AFR_03640 e91447d07d2774d61c379196453e4d9e 293 Gene3D G3DSA:3.20.20.70 4 242 5.7E-6 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_03640 e91447d07d2774d61c379196453e4d9e 293 SUPERFAMILY SSF102114 13 240 6.08E-14 T 12-10-2018 AFR_24515 9088bf50aefc4142dc11b1896051a600 348 Gene3D G3DSA:3.30.360.10 121 342 2.0E-10 T 12-10-2018 AFR_24515 9088bf50aefc4142dc11b1896051a600 348 SUPERFAMILY SSF51735 4 141 7.56E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24515 9088bf50aefc4142dc11b1896051a600 348 Gene3D G3DSA:3.40.50.720 2 120 2.4E-13 T 12-10-2018 AFR_08160 acc1ab3486496570c6a2a83a21a59f20 529 Pfam PF00672 HAMP domain 214 262 7.4E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_08160 acc1ab3486496570c6a2a83a21a59f20 529 SMART SM00304 214 266 2.6E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_08160 acc1ab3486496570c6a2a83a21a59f20 529 Gene3D G3DSA:1.10.287.950 214 528 1.4E-57 T 12-10-2018 AFR_08160 acc1ab3486496570c6a2a83a21a59f20 529 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 338 497 2.5E-32 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_08160 acc1ab3486496570c6a2a83a21a59f20 529 SUPERFAMILY SSF58104 234 527 1.96E-57 T 12-10-2018 AFR_08160 acc1ab3486496570c6a2a83a21a59f20 529 SMART SM00283 274 528 5.5E-42 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_08135 e4529474fd03324f159a38f10203e72f 161 SMART SM00960 8 96 3.1E-13 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_08135 e4529474fd03324f159a38f10203e72f 161 Gene3D G3DSA:3.30.450.30 8 124 2.0E-26 T 12-10-2018 AFR_08135 e4529474fd03324f159a38f10203e72f 161 SUPERFAMILY SSF103196 10 120 2.96E-23 T 12-10-2018 AFR_08135 e4529474fd03324f159a38f10203e72f 161 Pfam PF03259 Roadblock/LC7 domain 13 95 8.2E-15 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_23005 a9cdbbd71077e2eec81be7a6363a8a13 306 Gene3D G3DSA:3.40.50.720 2 263 8.8E-46 T 12-10-2018 AFR_23005 a9cdbbd71077e2eec81be7a6363a8a13 306 SUPERFAMILY SSF51735 3 277 6.41E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23005 a9cdbbd71077e2eec81be7a6363a8a13 306 Pfam PF13460 NAD(P)H-binding 9 143 6.1E-20 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_42875 5a28be446e2381af0ff9103f4b761bee 359 PIRSF PIRSF015578 1 359 5.9E-92 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFR_42875 5a28be446e2381af0ff9103f4b761bee 359 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 299 7.8E-31 T 12-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFR_42875 5a28be446e2381af0ff9103f4b761bee 359 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 353 3.1E-199 T 12-10-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria AFR_42875 5a28be446e2381af0ff9103f4b761bee 359 Gene3D G3DSA:3.30.360.10 190 299 2.1E-146 T 12-10-2018 AFR_42875 5a28be446e2381af0ff9103f4b761bee 359 SUPERFAMILY SSF55347 189 299 9.29E-35 T 12-10-2018 AFR_42875 5a28be446e2381af0ff9103f4b761bee 359 SUPERFAMILY SSF51735 3 355 7.88E-94 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_42875 5a28be446e2381af0ff9103f4b761bee 359 Gene3D G3DSA:3.40.50.720 4 352 2.1E-146 T 12-10-2018 AFR_10540 6d3870b62b11394598bec4eae3e998c0 152 PRINTS PR00162 Rieske 2Fe-2S subunit signature 92 103 1.3E-5 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFR_10540 6d3870b62b11394598bec4eae3e998c0 152 PRINTS PR00162 Rieske 2Fe-2S subunit signature 125 137 1.3E-5 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFR_10540 6d3870b62b11394598bec4eae3e998c0 152 PRINTS PR00162 Rieske 2Fe-2S subunit signature 112 124 1.3E-5 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFR_10540 6d3870b62b11394598bec4eae3e998c0 152 Gene3D G3DSA:2.102.10.10 64 152 6.9E-25 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_10540 6d3870b62b11394598bec4eae3e998c0 152 SUPERFAMILY SSF50022 62 151 3.93E-26 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_10540 6d3870b62b11394598bec4eae3e998c0 152 Pfam PF00355 Rieske [2Fe-2S] domain 66 139 1.5E-14 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFR_06690 5a1ebba005d72eed6a5f2932904749f9 173 Pfam PF08281 Sigma-70, region 4 101 154 6.0E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_06690 5a1ebba005d72eed6a5f2932904749f9 173 Gene3D G3DSA:1.10.10.10 98 164 1.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06690 5a1ebba005d72eed6a5f2932904749f9 173 Pfam PF04542 Sigma-70 region 2 11 76 1.5E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_06690 5a1ebba005d72eed6a5f2932904749f9 173 Gene3D G3DSA:1.10.1740.10 1 77 1.8E-11 T 12-10-2018 AFR_06690 5a1ebba005d72eed6a5f2932904749f9 173 SUPERFAMILY SSF88946 4 84 1.06E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_06690 5a1ebba005d72eed6a5f2932904749f9 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 156 5.3E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_06690 5a1ebba005d72eed6a5f2932904749f9 173 SUPERFAMILY SSF88659 100 158 3.71E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 SUPERFAMILY SSF51905 2 335 5.49E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 320 3.6E-46 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PIRSF PIRSF000350 1 470 2.5E-76 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 Gene3D G3DSA:3.50.50.60 6 330 1.9E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 SUPERFAMILY SSF55424 357 468 7.39E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 358 463 1.7E-22 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 462 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 354 375 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 435 3.7E-51 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 6.0E-20 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.0E-20 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 6.0E-20 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 6.0E-20 T 12-10-2018 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 Gene3D G3DSA:3.30.390.30 356 472 1.9E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_12945 9f66ee3b65dc56c391f4a40ff4251a99 473 Gene3D G3DSA:3.50.50.60 157 275 1.9E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17870 26c1f0687f138da82da48313409d26a6 340 SUPERFAMILY SSF75005 40 337 7.28E-70 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_17870 26c1f0687f138da82da48313409d26a6 340 Gene3D G3DSA:2.115.10.20 46 339 1.5E-79 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_17870 26c1f0687f138da82da48313409d26a6 340 PIRSF PIRSF026534 26 340 2.5E-101 T 12-10-2018 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 AFR_17870 26c1f0687f138da82da48313409d26a6 340 Pfam PF04616 Glycosyl hydrolases family 43 61 324 1.1E-47 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_02930 3e81b2c30b24fe415ce75dfc9db77c40 318 SUPERFAMILY SSF102198 79 298 2.88E-45 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_02930 3e81b2c30b24fe415ce75dfc9db77c40 318 Gene3D G3DSA:3.50.30.50 77 298 8.9E-47 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_02930 3e81b2c30b24fe415ce75dfc9db77c40 318 Pfam PF04199 Putative cyclase 82 237 8.0E-18 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_12885 11999949fa508b9d0a6fd8b4f156ea39 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12885 11999949fa508b9d0a6fd8b4f156ea39 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12885 11999949fa508b9d0a6fd8b4f156ea39 203 SUPERFAMILY SSF46689 6 79 1.3E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12885 11999949fa508b9d0a6fd8b4f156ea39 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 2.4E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12885 11999949fa508b9d0a6fd8b4f156ea39 203 SUPERFAMILY SSF48498 84 190 2.79E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12885 11999949fa508b9d0a6fd8b4f156ea39 203 Gene3D G3DSA:1.10.357.10 2 199 4.8E-71 T 12-10-2018 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 SUPERFAMILY SSF55347 175 481 1.54E-106 T 12-10-2018 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 1 482 3.0E-186 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 PIRSF PIRSF000110 1 483 2.7E-166 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 175 181 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 187 481 9.8E-109 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 Gene3D G3DSA:3.40.50.720 1 173 1.8E-47 T 12-10-2018 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 1 185 5.1E-56 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 Gene3D G3DSA:3.30.360.10 174 482 9.8E-116 T 12-10-2018 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 1 482 80.244 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 324 350 5.5E-44 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 141 154 5.5E-44 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 165 193 5.5E-44 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 217 234 5.5E-44 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 235 251 5.5E-44 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFR_10625 ad7da2e2631753e8f9f56dd776c58462 483 SUPERFAMILY SSF51735 1 188 9.05E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_04250 3e21b14cd36fc0b309309a77c5f23fbe 194 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 104 115 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_04250 3e21b14cd36fc0b309309a77c5f23fbe 194 Gene3D G3DSA:3.30.70.3270 34 185 1.5E-33 T 12-10-2018 AFR_04250 3e21b14cd36fc0b309309a77c5f23fbe 194 Pfam PF00037 4Fe-4S binding domain 99 119 8.4E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_04250 3e21b14cd36fc0b309309a77c5f23fbe 194 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 8 157 23.598 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04250 3e21b14cd36fc0b309309a77c5f23fbe 194 SUPERFAMILY SSF54862 42 140 1.3E-18 T 12-10-2018 AFR_11595 edb5d96ad4e2c8ac622f8a33a0f583c3 395 SUPERFAMILY SSF55781 29 137 7.75E-5 T 12-10-2018 AFR_11595 edb5d96ad4e2c8ac622f8a33a0f583c3 395 SMART SM00331 168 385 2.1E-29 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_11595 edb5d96ad4e2c8ac622f8a33a0f583c3 395 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 194 385 3.3E-41 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_11595 edb5d96ad4e2c8ac622f8a33a0f583c3 395 Gene3D G3DSA:3.60.40.10 167 391 3.7E-47 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_11595 edb5d96ad4e2c8ac622f8a33a0f583c3 395 SUPERFAMILY SSF81606 182 385 9.42E-12 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_42360 400d76854e8c487edf084e64d14a2b44 133 Pfam PF10756 Bacterial PH domain 53 128 4.3E-9 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 AFR_03255 98cc9807f5daa310775c1994f53db2e4 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 304 2.9E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_34315 11b19e1b4c046bde2534a9f108dbc66a 247 Gene3D G3DSA:3.40.50.1820 2 247 2.5E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_34315 11b19e1b4c046bde2534a9f108dbc66a 247 SUPERFAMILY SSF53474 6 244 1.44E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_34315 11b19e1b4c046bde2534a9f108dbc66a 247 Pfam PF00756 Putative esterase 82 245 4.1E-11 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFR_16515 85388db15185f0332b46b7fc69917583 711 Pfam PF01757 Acyltransferase family 34 351 4.3E-23 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_16515 85388db15185f0332b46b7fc69917583 711 SUPERFAMILY SSF52266 489 703 7.33E-5 T 12-10-2018 AFR_06395 bb49fe82c00878838737c455d57d0673 410 SUPERFAMILY SSF63829 51 382 4.58E-13 T 12-10-2018 AFR_06395 bb49fe82c00878838737c455d57d0673 410 Gene3D G3DSA:2.130.10.10 41 193 1.0E-5 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_05755 dce4a0107758e2239200d67de5ec4089 381 Pfam PF09375 Imelysin 143 373 1.9E-41 T 12-10-2018 IPR018976 Imelysin-like domain AFR_05755 dce4a0107758e2239200d67de5ec4089 381 Gene3D G3DSA:1.20.1420.20 135 381 9.8E-92 T 12-10-2018 IPR038352 Imelysin-like domain superfamily AFR_05755 dce4a0107758e2239200d67de5ec4089 381 Pfam PF13473 Cupredoxin-like domain 35 127 8.8E-10 T 12-10-2018 IPR028096 EfeO-type cupredoxin-like domain AFR_03635 51447a05db60fb71ab8c857a07c5a128 435 SUPERFAMILY SSF102114 6 420 9.68E-71 T 12-10-2018 AFR_03635 51447a05db60fb71ab8c857a07c5a128 435 SMART SM00729 40 260 6.5E-30 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFR_03635 51447a05db60fb71ab8c857a07c5a128 435 Gene3D G3DSA:3.80.30.20 5 326 6.3E-67 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFR_03635 51447a05db60fb71ab8c857a07c5a128 435 Pfam PF04055 Radical SAM superfamily 45 213 1.1E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_11475 470923037e1c4e30c0a38bee7c6b1047 124 SMART SM00448 2 115 8.7E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11475 470923037e1c4e30c0a38bee7c6b1047 124 Gene3D G3DSA:3.40.50.12740 3 124 3.6E-42 T 12-10-2018 AFR_11475 470923037e1c4e30c0a38bee7c6b1047 124 Pfam PF00072 Response regulator receiver domain 4 116 2.5E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_11475 470923037e1c4e30c0a38bee7c6b1047 124 SUPERFAMILY SSF52172 4 123 2.56E-39 T 12-10-2018 IPR011006 CheY-like superfamily AFR_02125 59059d5c0668280604a856480b0a04e5 111 Pfam PF10745 Protein of unknown function (DUF2530) 43 96 1.9E-7 T 12-10-2018 IPR019681 Protein of unknown function DUF2530 AFR_09125 d97f41680ef137aed127e0636657471b 73 SUPERFAMILY SSF46955 15 66 1.34E-8 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_09125 d97f41680ef137aed127e0636657471b 73 Pfam PF12728 Helix-turn-helix domain 17 66 4.9E-12 T 12-10-2018 AFR_41470 6a5bd511362830d3b30c56ff52b538b8 301 SUPERFAMILY SSF51717 24 287 5.49E-93 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_41470 6a5bd511362830d3b30c56ff52b538b8 301 Pfam PF00809 Pterin binding enzyme 27 272 3.7E-83 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_41470 6a5bd511362830d3b30c56ff52b538b8 301 Gene3D G3DSA:3.20.20.20 3 293 3.4E-106 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_41470 6a5bd511362830d3b30c56ff52b538b8 301 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 60 73 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_41470 6a5bd511362830d3b30c56ff52b538b8 301 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 26 286 1.9E-90 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 AFR_41470 6a5bd511362830d3b30c56ff52b538b8 301 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 26 41 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFR_23565 24a8d3ccf72d5b66182a146a4af5860e 325 Gene3D G3DSA:3.50.30.60 173 324 5.0E-35 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_23565 24a8d3ccf72d5b66182a146a4af5860e 325 Pfam PF02016 LD-carboxypeptidase 15 309 7.3E-58 T 12-10-2018 IPR003507 Peptidase family S66 AFR_23565 24a8d3ccf72d5b66182a146a4af5860e 325 SUPERFAMILY SSF141986 171 315 2.88E-26 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily AFR_23565 24a8d3ccf72d5b66182a146a4af5860e 325 SUPERFAMILY SSF52317 2 154 1.92E-30 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_23565 24a8d3ccf72d5b66182a146a4af5860e 325 PIRSF PIRSF028757 2 324 5.1E-54 T 12-10-2018 IPR003507 Peptidase family S66 AFR_23565 24a8d3ccf72d5b66182a146a4af5860e 325 Gene3D G3DSA:3.40.50.10740 2 164 4.2E-41 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal AFR_16440 949a15c5445bc9f71b6b7e7af60732cb 138 Pfam PF00293 NUDIX domain 2 115 9.4E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_16440 949a15c5445bc9f71b6b7e7af60732cb 138 SUPERFAMILY SSF55811 1 114 2.3E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_16440 949a15c5445bc9f71b6b7e7af60732cb 138 PRINTS PR00502 NUDIX hydrolase family signature 42 57 4.4E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_16440 949a15c5445bc9f71b6b7e7af60732cb 138 PRINTS PR00502 NUDIX hydrolase family signature 28 42 4.4E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_16440 949a15c5445bc9f71b6b7e7af60732cb 138 ProSitePatterns PS00893 Nudix box signature. 33 54 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_16440 949a15c5445bc9f71b6b7e7af60732cb 138 Gene3D G3DSA:3.90.79.10 1 120 3.2E-27 T 12-10-2018 AFR_41980 f7a5df9b3d8905edbb023ee0ee488a6d 196 Pfam PF07290 Protein of unknown function (DUF1449) 5 174 6.5E-10 T 12-10-2018 IPR010840 Protein of unknown function DUF1449 AFR_34820 429c84e6302c866c3e3e0176c14ae85a 213 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 70 140 4.4E-13 T 12-10-2018 AFR_34820 429c84e6302c866c3e3e0176c14ae85a 213 SUPERFAMILY SSF53335 44 173 4.4E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_34820 429c84e6302c866c3e3e0176c14ae85a 213 Gene3D G3DSA:3.40.50.150 23 200 1.9E-21 T 12-10-2018 AFR_20645 f1cc2b02928e11637a59e9994281c12a 215 Gene3D G3DSA:1.10.3630.10 2 212 1.1E-8 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily AFR_20645 f1cc2b02928e11637a59e9994281c12a 215 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 190 2.5E-29 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 AFR_39105 bb05eee654d6abf3eb64164b0a7ab357 137 Gene3D G3DSA:3.40.50.1010 12 132 2.2E-7 T 12-10-2018 AFR_39105 bb05eee654d6abf3eb64164b0a7ab357 137 SUPERFAMILY SSF88723 13 127 1.1E-6 T 12-10-2018 IPR029060 PIN-like domain superfamily AFR_16860 3d380b2349c2a2cbcb34154808c525d4 469 Pfam PF02614 Glucuronate isomerase 20 452 5.5E-73 T 12-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 AFR_16860 3d380b2349c2a2cbcb34154808c525d4 469 Gene3D G3DSA:3.20.20.140 20 454 1.4E-130 T 12-10-2018 AFR_16860 3d380b2349c2a2cbcb34154808c525d4 469 Gene3D G3DSA:1.10.2020.10 51 149 1.4E-130 T 12-10-2018 AFR_16860 3d380b2349c2a2cbcb34154808c525d4 469 SUPERFAMILY SSF51556 6 468 4.08E-141 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_42815 981c299c63f5990dad803bf00e854aa7 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 2.7E-26 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal AFR_42815 981c299c63f5990dad803bf00e854aa7 149 SUPERFAMILY SSF55653 57 147 2.49E-24 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily AFR_42815 981c299c63f5990dad803bf00e854aa7 149 SUPERFAMILY SSF55658 1 57 7.15E-18 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal AFR_42815 981c299c63f5990dad803bf00e854aa7 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.3E-39 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_42815 981c299c63f5990dad803bf00e854aa7 149 Gene3D G3DSA:3.10.430.100 61 149 3.3E-26 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily AFR_42815 981c299c63f5990dad803bf00e854aa7 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 1.6E-21 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42815 981c299c63f5990dad803bf00e854aa7 149 Gene3D G3DSA:3.40.5.10 1 60 1.4E-20 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42815 981c299c63f5990dad803bf00e854aa7 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_42815 981c299c63f5990dad803bf00e854aa7 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.035 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 3.8E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 197 211 3.8E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 43 58 3.8E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 3.8E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 Pfam PF00561 alpha/beta hydrolase fold 187 238 8.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 Pfam PF00561 alpha/beta hydrolase fold 18 128 3.4E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 SUPERFAMILY SSF53474 7 249 9.34E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 7 249 3.5E-93 T 12-10-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 AFR_19265 d2b7ea717e44dce472c8f1d7182dc685 253 Gene3D G3DSA:3.40.50.1820 3 252 2.1E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_00965 91f966d6e3f1744ace428960380ca6d2 250 Pfam PF05239 PRC-barrel domain 6 75 1.3E-12 T 12-10-2018 IPR027275 PRC-barrel domain AFR_00965 91f966d6e3f1744ace428960380ca6d2 250 Gene3D G3DSA:3.90.50.10 2 108 8.2E-13 T 12-10-2018 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 AFR_00965 91f966d6e3f1744ace428960380ca6d2 250 SUPERFAMILY SSF50346 9 110 2.98E-24 T 12-10-2018 IPR011033 PRC-barrel-like superfamily AFR_00965 91f966d6e3f1744ace428960380ca6d2 250 Pfam PF09557 Domain of unknown function (DUF2382) 129 240 2.6E-33 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 AFR_20735 a8f85662109c5266c52951b918b3af33 286 SUPERFAMILY SSF51658 1 281 1.57E-56 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_20735 a8f85662109c5266c52951b918b3af33 286 Gene3D G3DSA:3.20.20.150 1 285 4.6E-47 T 12-10-2018 AFR_20735 a8f85662109c5266c52951b918b3af33 286 Pfam PF01261 Xylose isomerase-like TIM barrel 21 237 3.5E-35 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_18365 28173278db0a7d34094e0314bfda5221 397 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 55 265 2.5E-14 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFR_18365 28173278db0a7d34094e0314bfda5221 397 SUPERFAMILY SSF50621 249 394 7.12E-15 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_18365 28173278db0a7d34094e0314bfda5221 397 Gene3D G3DSA:3.20.20.10 38 265 7.5E-34 T 12-10-2018 IPR029066 PLP-binding barrel AFR_18365 28173278db0a7d34094e0314bfda5221 397 SUPERFAMILY SSF51419 26 271 9.16E-32 T 12-10-2018 IPR029066 PLP-binding barrel AFR_18365 28173278db0a7d34094e0314bfda5221 397 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 367 380 1.3E-5 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_18365 28173278db0a7d34094e0314bfda5221 397 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 58 76 1.3E-5 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_18365 28173278db0a7d34094e0314bfda5221 397 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 90 1.3E-5 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_18365 28173278db0a7d34094e0314bfda5221 397 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 260 279 1.3E-5 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFR_18365 28173278db0a7d34094e0314bfda5221 397 Gene3D G3DSA:2.40.37.10 266 396 1.3E-12 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFR_08515 d365d2ced7090e6149524d30e8c1aefe 332 Pfam PF06271 RDD family 26 164 1.4E-18 T 12-10-2018 IPR010432 RDD AFR_35195 bdbbdbb5de4ee5b1987399fa48f51591 315 Pfam PF06626 Protein of unknown function (DUF1152) 98 300 2.8E-16 T 12-10-2018 IPR010581 Protein of unknown function DUF1152 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 327 2.9E-44 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 SUPERFAMILY SSF51905 154 341 2.0E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17130 d39779637100d0a216f13cff55e6fbef 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 6.4E-10 T 12-10-2018 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.4E-10 T 12-10-2018 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 6.4E-10 T 12-10-2018 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 6.4E-10 T 12-10-2018 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 SUPERFAMILY SSF51905 2 183 4.07E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17130 d39779637100d0a216f13cff55e6fbef 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.6E-7 T 12-10-2018 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 1.6E-7 T 12-10-2018 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 185 1.6E-7 T 12-10-2018 AFR_17130 d39779637100d0a216f13cff55e6fbef 445 Gene3D G3DSA:3.50.50.100 1 401 8.6E-109 T 12-10-2018 AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 76 177 2.7E-17 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 2.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 140 2.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 162 2.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 Gene3D G3DSA:1.10.150.240 21 83 4.9E-45 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 SUPERFAMILY SSF56784 6 199 2.53E-43 T 12-10-2018 IPR036412 HAD-like superfamily AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 Gene3D G3DSA:3.40.50.1000 7 180 4.9E-45 T 12-10-2018 IPR023214 HAD superfamily AFR_31435 635bc3b2335ddb25ad235f86be63f54e 201 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 179 1.3E-19 T 12-10-2018 AFR_29195 db44740a01446083457506a702670ffd 476 SUPERFAMILY SSF51445 35 323 1.78E-31 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_29195 db44740a01446083457506a702670ffd 476 Gene3D G3DSA:3.20.20.80 33 316 6.8E-35 T 12-10-2018 AFR_29195 db44740a01446083457506a702670ffd 476 SMART SM00458 350 476 9.9E-23 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_29195 db44740a01446083457506a702670ffd 476 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 51 295 1.1E-16 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AFR_29195 db44740a01446083457506a702670ffd 476 SUPERFAMILY SSF50370 347 474 8.92E-39 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_29195 db44740a01446083457506a702670ffd 476 Gene3D G3DSA:2.80.10.50 347 475 2.5E-42 T 12-10-2018 AFR_29195 db44740a01446083457506a702670ffd 476 Pfam PF00652 Ricin-type beta-trefoil lectin domain 352 473 9.7E-28 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_06455 a878afbf861cd32a4a794b637e75f15d 184 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 7.6E-14 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_06455 a878afbf861cd32a4a794b637e75f15d 184 Pfam PF10400 Virulence activator alpha C-term 92 180 2.4E-20 T 12-10-2018 IPR018309 Transcription regulator PadR, C-terminal AFR_06455 a878afbf861cd32a4a794b637e75f15d 184 SUPERFAMILY SSF46785 2 181 1.34E-39 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06455 a878afbf861cd32a4a794b637e75f15d 184 Gene3D G3DSA:1.10.10.10 1 88 2.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20635 7051f76aa86b5e0fa3bd0c436626536a 403 Pfam PF07394 Protein of unknown function (DUF1501) 225 370 5.7E-27 T 12-10-2018 IPR010869 Protein of unknown function DUF1501 AFR_25360 62d8941269615e61b8bca7341eaefade 418 Pfam PF12323 Helix-turn-helix domain 11 55 1.8E-14 T 12-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFR_25360 62d8941269615e61b8bca7341eaefade 418 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 262 333 2.6E-6 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_25360 62d8941269615e61b8bca7341eaefade 418 Pfam PF01385 Probable transposase 183 291 2.0E-22 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFR_25360 62d8941269615e61b8bca7341eaefade 418 Pfam PF07282 Putative transposase DNA-binding domain 306 373 3.5E-19 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFR_20310 8a27588e84e6deeb8837bcaa1fa978c7 362 Gene3D G3DSA:2.50.20.10 31 244 9.1E-21 T 12-10-2018 AFR_20310 8a27588e84e6deeb8837bcaa1fa978c7 362 SUPERFAMILY SSF89392 97 244 1.92E-11 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 Gene3D G3DSA:3.40.50.80 136 261 8.2E-22 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 275 341 1.7E-6 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 Gene3D G3DSA:3.10.20.30 262 351 3.7E-12 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 PRINTS PR00410 Phenol hydroxylase reductase family signature 68 80 4.7E-5 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 PRINTS PR00410 Phenol hydroxylase reductase family signature 128 137 4.7E-5 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 PRINTS PR00410 Phenol hydroxylase reductase family signature 144 163 4.7E-5 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 SUPERFAMILY SSF52343 129 261 4.45E-21 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 SUPERFAMILY SSF54292 248 351 1.44E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 Pfam PF00970 Oxidoreductase FAD-binding domain 70 133 1.6E-7 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 Gene3D G3DSA:2.40.30.10 33 131 2.2E-18 T 12-10-2018 AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 SUPERFAMILY SSF63380 39 135 6.98E-20 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_25125 1ef66dbc78e7bef5c64c8732a7492d7d 352 Pfam PF00175 Oxidoreductase NAD-binding domain 145 237 1.5E-7 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFR_34240 322a93a34c63277d3656f2f921e104fb 111 Pfam PF13560 Helix-turn-helix domain 21 85 1.6E-6 T 12-10-2018 AFR_34240 322a93a34c63277d3656f2f921e104fb 111 Gene3D G3DSA:1.10.260.40 16 106 1.9E-5 T 12-10-2018 AFR_05640 4009f5e370e66f7665648a2adf8a1d76 182 Pfam PF00293 NUDIX domain 46 168 7.3E-10 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_05640 4009f5e370e66f7665648a2adf8a1d76 182 SUPERFAMILY SSF55811 39 180 9.75E-21 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_05640 4009f5e370e66f7665648a2adf8a1d76 182 Gene3D G3DSA:3.90.79.10 4 179 1.2E-35 T 12-10-2018 AFR_05075 968ea367c0e28058614f2c9d2769cb0b 281 Pfam PF01551 Peptidase family M23 166 259 8.7E-33 T 12-10-2018 IPR016047 Peptidase M23 AFR_05075 968ea367c0e28058614f2c9d2769cb0b 281 SUPERFAMILY SSF51261 135 265 5.23E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_05075 968ea367c0e28058614f2c9d2769cb0b 281 Gene3D G3DSA:2.70.70.10 135 268 7.8E-43 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_19900 6264da5a0715a94f53aae434e3035bfb 491 Pfam PF02447 GntP family permease 16 216 9.6E-58 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFR_19900 6264da5a0715a94f53aae434e3035bfb 491 Pfam PF02447 GntP family permease 267 488 8.0E-74 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFR_19900 6264da5a0715a94f53aae434e3035bfb 491 PIRSF PIRSF002746 10 491 7.6E-141 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 SUPERFAMILY SSF88946 12 110 2.59E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 Gene3D G3DSA:1.10.10.10 95 180 1.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 176 9.9E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 Pfam PF08281 Sigma-70, region 4 124 174 1.4E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 SUPERFAMILY SSF88659 118 179 1.57E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 Gene3D G3DSA:1.10.1740.10 19 94 2.2E-11 T 12-10-2018 AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 23 179 4.4E-43 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_19990 3d50ff7eb9a32ff392dc5b85423f9e13 185 Pfam PF04542 Sigma-70 region 2 32 97 8.8E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_41280 592b91cc295344f79490f021a1673c56 161 SUPERFAMILY SSF141259 3 65 2.62E-14 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily AFR_41280 592b91cc295344f79490f021a1673c56 161 Pfam PF02559 CarD-like/TRCF domain 3 111 5.1E-17 T 12-10-2018 IPR003711 CarD-like/TRCF domain AFR_41280 592b91cc295344f79490f021a1673c56 161 Gene3D G3DSA:2.30.30.840 1 60 1.7E-25 T 12-10-2018 AFR_41280 592b91cc295344f79490f021a1673c56 161 Gene3D G3DSA:1.20.58.1290 61 161 1.7E-36 T 12-10-2018 AFR_41280 592b91cc295344f79490f021a1673c56 161 SMART SM01058 2 112 1.3E-32 T 12-10-2018 IPR003711 CarD-like/TRCF domain AFR_17090 129ff0e17c50e95338f4588b19ddeb2b 409 Gene3D G3DSA:3.90.1150.10 35 394 2.4E-86 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_17090 129ff0e17c50e95338f4588b19ddeb2b 409 SUPERFAMILY SSF53383 16 399 3.06E-62 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_17090 129ff0e17c50e95338f4588b19ddeb2b 409 Gene3D G3DSA:3.40.640.10 56 304 2.4E-86 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_17090 129ff0e17c50e95338f4588b19ddeb2b 409 Pfam PF00155 Aminotransferase class I and II 80 392 2.4E-26 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_02335 5f684bc61a5d1b6beeef3c0dd6ec649d 138 SUPERFAMILY SSF55729 17 125 1.03E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_02335 5f684bc61a5d1b6beeef3c0dd6ec649d 138 Pfam PF13302 Acetyltransferase (GNAT) domain 35 118 3.2E-14 T 12-10-2018 IPR000182 GNAT domain AFR_02335 5f684bc61a5d1b6beeef3c0dd6ec649d 138 Gene3D G3DSA:3.40.630.30 6 137 8.8E-20 T 12-10-2018 AFR_04310 065a61230a2ab5e31292e7b975d712f6 176 ProSitePatterns PS01081 TetR-type HTH domain signature. 13 44 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_04310 065a61230a2ab5e31292e7b975d712f6 176 SUPERFAMILY SSF46689 3 45 9.23E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_04310 065a61230a2ab5e31292e7b975d712f6 176 Gene3D G3DSA:1.10.357.10 40 169 1.6E-17 T 12-10-2018 AFR_04310 065a61230a2ab5e31292e7b975d712f6 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04310 065a61230a2ab5e31292e7b975d712f6 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04310 065a61230a2ab5e31292e7b975d712f6 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 44 6.1E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_04310 065a61230a2ab5e31292e7b975d712f6 176 Gene3D G3DSA:1.10.10.60 1 37 3.2E-16 T 12-10-2018 AFR_19600 39c088526f121dc72b7e1971d0043183 381 SUPERFAMILY SSF56176 14 189 2.15E-36 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFR_19600 39c088526f121dc72b7e1971d0043183 381 Gene3D G3DSA:3.30.465.40 5 202 1.6E-43 T 12-10-2018 AFR_19600 39c088526f121dc72b7e1971d0043183 381 SUPERFAMILY SSF55103 201 378 3.11E-11 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFR_19600 39c088526f121dc72b7e1971d0043183 381 Pfam PF01565 FAD binding domain 19 151 1.4E-21 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFR_14160 123d55c9ac78d944146a4809f4a58b9a 225 Pfam PF03458 UPF0126 domain 99 173 1.5E-11 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 AFR_14160 123d55c9ac78d944146a4809f4a58b9a 225 Pfam PF03458 UPF0126 domain 11 87 2.4E-13 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 AFR_15660 a5c61d36abc44e19d64b53f76366bb58 121 Pfam PF07883 Cupin domain 41 96 6.6E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_15660 a5c61d36abc44e19d64b53f76366bb58 121 SUPERFAMILY SSF51182 20 120 2.53E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_15660 a5c61d36abc44e19d64b53f76366bb58 121 Gene3D G3DSA:2.60.120.10 2 121 1.4E-35 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_36645 995541a2dc54dbbd6af3ac8360f22c87 367 PIRSF PIRSF001434 2 367 3.4E-97 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFR_36645 995541a2dc54dbbd6af3ac8360f22c87 367 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 43 364 7.8E-83 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFR_36645 995541a2dc54dbbd6af3ac8360f22c87 367 Gene3D G3DSA:3.90.1150.10 245 367 9.2E-29 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_36645 995541a2dc54dbbd6af3ac8360f22c87 367 Gene3D G3DSA:3.40.640.10 5 244 3.3E-59 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_36645 995541a2dc54dbbd6af3ac8360f22c87 367 SUPERFAMILY SSF53383 36 366 2.25E-81 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_12755 ffa8d339a160427c37ff640d055b851f 247 Gene3D G3DSA:3.30.70.100 136 229 1.3E-9 T 12-10-2018 AFR_12755 ffa8d339a160427c37ff640d055b851f 247 SUPERFAMILY SSF54909 141 217 2.39E-7 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_35980 e06e5852fb6ce4e14551c9526eaf9e39 112 SUPERFAMILY SSF64376 4 81 3.27E-20 T 12-10-2018 IPR035931 YlxR-like superfamily AFR_35980 e06e5852fb6ce4e14551c9526eaf9e39 112 Gene3D G3DSA:3.30.1230.10 2 87 3.7E-13 T 12-10-2018 IPR035931 YlxR-like superfamily AFR_35980 e06e5852fb6ce4e14551c9526eaf9e39 112 Pfam PF04296 Protein of unknown function (DUF448) 6 75 8.8E-21 T 12-10-2018 IPR007393 Domain of unknown function DUF448 AFR_13235 1d57ba266b7b67c02f87933fbdb7058d 529 SUPERFAMILY SSF58104 234 527 3.66E-58 T 12-10-2018 AFR_13235 1d57ba266b7b67c02f87933fbdb7058d 529 SMART SM00283 274 528 2.8E-43 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_13235 1d57ba266b7b67c02f87933fbdb7058d 529 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 337 500 3.3E-30 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_13235 1d57ba266b7b67c02f87933fbdb7058d 529 Gene3D G3DSA:1.10.287.950 215 529 3.2E-56 T 12-10-2018 AFR_30120 3434080e476952571c61e59e5dcb793b 311 Gene3D G3DSA:1.10.287.130 56 182 9.4E-8 T 12-10-2018 AFR_30120 3434080e476952571c61e59e5dcb793b 311 Pfam PF07730 Histidine kinase 122 186 1.7E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_30120 3434080e476952571c61e59e5dcb793b 311 SUPERFAMILY SSF55874 195 309 3.16E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30120 3434080e476952571c61e59e5dcb793b 311 Gene3D G3DSA:3.30.565.10 190 310 2.9E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30120 3434080e476952571c61e59e5dcb793b 311 SMART SM00304 57 109 3.8E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_07870 695b0657183df110875382f969c4ebc4 70 Gene3D G3DSA:3.90.820.10 1 70 4.0E-36 T 12-10-2018 AFR_07870 695b0657183df110875382f969c4ebc4 70 SUPERFAMILY SSF160582 3 67 1.7E-29 T 12-10-2018 IPR038020 MbtH-like domain superfamily AFR_07870 695b0657183df110875382f969c4ebc4 70 Pfam PF03621 MbtH-like protein 2 53 3.5E-28 T 12-10-2018 IPR005153 MbtH-like domain AFR_07870 695b0657183df110875382f969c4ebc4 70 SMART SM00923 4 54 2.8E-31 T 12-10-2018 IPR005153 MbtH-like domain AFR_15540 9a8b3517b19b3ab854d0a2e5b3522194 353 TIGRFAM TIGR03886 lyase_spl_fam: spore photoproduct lyase family protein 8 353 2.1E-193 T 12-10-2018 IPR023805 Uncharacterised protein family, spore photo-product lyase-related AFR_15540 9a8b3517b19b3ab854d0a2e5b3522194 353 Gene3D G3DSA:3.40.50.12110 7 117 2.4E-30 T 12-10-2018 AFR_15540 9a8b3517b19b3ab854d0a2e5b3522194 353 Gene3D G3DSA:3.80.30.30 132 353 4.7E-41 T 12-10-2018 AFR_26765 b834dba63d0b264f07cb27caec5be9f2 133 Pfam PF13637 Ankyrin repeats (many copies) 46 98 9.1E-10 T 12-10-2018 AFR_26765 b834dba63d0b264f07cb27caec5be9f2 133 SUPERFAMILY SSF48403 17 127 1.1E-19 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_26765 b834dba63d0b264f07cb27caec5be9f2 133 Gene3D G3DSA:1.25.40.20 3 120 1.2E-21 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_26765 b834dba63d0b264f07cb27caec5be9f2 133 SMART SM00248 44 73 0.0096 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_26765 b834dba63d0b264f07cb27caec5be9f2 133 SMART SM00248 77 106 6.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_34225 abefd306d4de017056ceecb0e1a03776 239 Pfam PF05630 Necrosis inducing protein (NPP1) 22 225 2.4E-59 T 12-10-2018 IPR008701 Necrosis inducing protein AFR_34225 abefd306d4de017056ceecb0e1a03776 239 PIRSF PIRSF029958 1 239 2.6E-91 T 12-10-2018 IPR008701 Necrosis inducing protein AFR_00375 23e42edc26bf7a88ac6c2c627ea77e48 96 SMART SM00530 32 87 1.2E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_00375 23e42edc26bf7a88ac6c2c627ea77e48 96 Pfam PF13560 Helix-turn-helix domain 29 85 3.4E-13 T 12-10-2018 AFR_00375 23e42edc26bf7a88ac6c2c627ea77e48 96 SUPERFAMILY SSF47413 20 93 7.88E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_00375 23e42edc26bf7a88ac6c2c627ea77e48 96 Gene3D G3DSA:1.10.260.40 8 94 1.4E-15 T 12-10-2018 AFR_19345 d0177d6aeca1f559e5ff5848a9a9cb06 437 Gene3D G3DSA:3.40.190.10 52 372 5.6E-61 T 12-10-2018 AFR_19345 d0177d6aeca1f559e5ff5848a9a9cb06 437 Pfam PF01547 Bacterial extracellular solute-binding protein 52 343 8.6E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_19345 d0177d6aeca1f559e5ff5848a9a9cb06 437 Gene3D G3DSA:3.40.190.10 150 381 5.6E-61 T 12-10-2018 AFR_19345 d0177d6aeca1f559e5ff5848a9a9cb06 437 SUPERFAMILY SSF53850 19 348 1.88E-57 T 12-10-2018 AFR_39645 0731f1785c76cba7986807eaddc19cbc 107 Pfam PF01022 Bacterial regulatory protein, arsR family 15 59 7.9E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39645 0731f1785c76cba7986807eaddc19cbc 107 SMART SM00418 8 86 1.0E-26 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39645 0731f1785c76cba7986807eaddc19cbc 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.3E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39645 0731f1785c76cba7986807eaddc19cbc 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.3E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39645 0731f1785c76cba7986807eaddc19cbc 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.3E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_39645 0731f1785c76cba7986807eaddc19cbc 107 SUPERFAMILY SSF46785 10 101 9.67E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_39645 0731f1785c76cba7986807eaddc19cbc 107 Gene3D G3DSA:1.10.10.10 10 106 3.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 811 23.368 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 SMART SM00434 8 466 2.1E-276 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Gene3D G3DSA:2.120.10.90 502 811 2.3E-121 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 5 809 0.0 T 12-10-2018 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 762 807 5.7E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 589 4.2E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 712 758 2.3E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 552 4.0E-12 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 612 653 1.3E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 707 1.8E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 SUPERFAMILY SSF56719 27 489 1.44E-170 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Gene3D G3DSA:3.30.1360.40 237 334 4.5E-199 T 12-10-2018 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 SUPERFAMILY SSF101904 500 815 2.75E-98 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 473 7.6E-150 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Gene3D G3DSA:3.90.199.10 29 488 4.5E-199 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFR_00045 566fb2abbc33a4a4d588c09d789c1b0f 817 Gene3D G3DSA:1.10.268.10 371 459 4.5E-199 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 SUPERFAMILY SSF56322 22 504 3.14E-151 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 PRINTS PR00095 Anthranilate synthase component I signature 344 357 3.7E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 PRINTS PR00095 Anthranilate synthase component I signature 358 371 3.7E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 PRINTS PR00095 Anthranilate synthase component I signature 438 452 3.7E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 PRINTS PR00095 Anthranilate synthase component I signature 453 467 3.7E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 33 504 8.5E-167 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 Gene3D G3DSA:3.60.120.10 2 513 7.0E-189 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFR_10290 81cb54be922d75312eafac26517ee9a1 514 Pfam PF00425 chorismate binding enzyme 240 496 3.6E-98 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFR_10290 81cb54be922d75312eafac26517ee9a1 514 Pfam PF04715 Anthranilate synthase component I, N terminal region 34 177 7.9E-29 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_11205 1f61958de7238083a84e48067a76be48 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 291 4.6E-7 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_11205 1f61958de7238083a84e48067a76be48 303 Gene3D G3DSA:1.10.3720.10 47 301 7.3E-59 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11205 1f61958de7238083a84e48067a76be48 303 SUPERFAMILY SSF161098 51 289 2.49E-45 T 12-10-2018 IPR035906 MetI-like superfamily AFR_26650 9ae0b7c2eddba6ac11b96299d285827c 350 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 1.1E-117 T 12-10-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c AFR_26650 9ae0b7c2eddba6ac11b96299d285827c 350 SUPERFAMILY SSF51679 2 341 1.57E-72 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_26650 9ae0b7c2eddba6ac11b96299d285827c 350 Gene3D G3DSA:3.20.20.30 2 342 1.4E-82 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_26650 9ae0b7c2eddba6ac11b96299d285827c 350 Pfam PF00296 Luciferase-like monooxygenase 14 317 2.2E-79 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_40965 bc0f895736f4116535f35a8d200ccdf8 233 Gene3D G3DSA:1.10.287.1060 79 172 2.7E-6 T 12-10-2018 AFR_40965 bc0f895736f4116535f35a8d200ccdf8 233 SUPERFAMILY SSF140453 89 161 1.2E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily AFR_08600 249ecec6edce9b8d1394614fe5e34ba5 306 SUPERFAMILY SSF53613 17 290 1.31E-41 T 12-10-2018 IPR029056 Ribokinase-like AFR_08600 249ecec6edce9b8d1394614fe5e34ba5 306 Pfam PF00294 pfkB family carbohydrate kinase 18 282 3.6E-31 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_08600 249ecec6edce9b8d1394614fe5e34ba5 306 Gene3D G3DSA:3.40.1190.20 3 304 4.0E-55 T 12-10-2018 IPR029056 Ribokinase-like AFR_08600 249ecec6edce9b8d1394614fe5e34ba5 306 PIRSF PIRSF000535 5 300 4.1E-42 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFR_03025 534ed601cad8a220491bb6584d966df6 381 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 108 134 0.02 T 12-10-2018 IPR013431 Delta-60 repeat AFR_03025 534ed601cad8a220491bb6584d966df6 381 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 152 184 6.3E-4 T 12-10-2018 IPR013431 Delta-60 repeat AFR_03025 534ed601cad8a220491bb6584d966df6 381 SUPERFAMILY SSF50998 34 340 4.12E-14 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_00185 7e3b44d7288d573956b96d9d05d07610 431 Pfam PF03777 Small secreted domain (DUF320) 107 140 5.6E-6 T 12-10-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species AFR_00185 7e3b44d7288d573956b96d9d05d07610 431 Pfam PF03777 Small secreted domain (DUF320) 159 199 3.2E-8 T 12-10-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species AFR_00185 7e3b44d7288d573956b96d9d05d07610 431 Pfam PF03777 Small secreted domain (DUF320) 273 308 3.6E-8 T 12-10-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species AFR_00185 7e3b44d7288d573956b96d9d05d07610 431 Pfam PF03777 Small secreted domain (DUF320) 27 70 4.2E-5 T 12-10-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species AFR_02460 321d23595f7f15f6c34ca766495b137f 302 Gene3D G3DSA:3.90.550.10 2 231 2.4E-7 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02460 321d23595f7f15f6c34ca766495b137f 302 SUPERFAMILY SSF53448 3 234 1.91E-15 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02460 321d23595f7f15f6c34ca766495b137f 302 Pfam PF11397 Glycosyltransferase (GlcNAc) 2 48 8.4E-9 T 12-10-2018 IPR021067 Glycosyltransferase, GlcNAc AFR_02460 321d23595f7f15f6c34ca766495b137f 302 Pfam PF11397 Glycosyltransferase (GlcNAc) 51 287 9.7E-55 T 12-10-2018 IPR021067 Glycosyltransferase, GlcNAc AFR_19075 ccbdb061bba19eb1f668d0ec7b9ed2ef 225 Gene3D G3DSA:2.60.40.10 125 224 6.0E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_19075 ccbdb061bba19eb1f668d0ec7b9ed2ef 225 SUPERFAMILY SSF49265 130 223 1.39E-10 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFR_40795 700e32a25b285b0876ef1a7eafed3fae 335 Pfam PF01384 Phosphate transporter family 22 323 7.8E-81 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 AFR_35380 201f900064489fbee6580ef5ee246a7c 238 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 8 215 8.1E-70 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_35380 201f900064489fbee6580ef5ee246a7c 238 PIRSF PIRSF001357 3 227 2.5E-69 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_35380 201f900064489fbee6580ef5ee246a7c 238 Gene3D G3DSA:3.20.20.70 2 225 1.5E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_35380 201f900064489fbee6580ef5ee246a7c 238 SUPERFAMILY SSF51569 4 218 1.05E-72 T 12-10-2018 AFR_35380 201f900064489fbee6580ef5ee246a7c 238 Pfam PF01791 DeoC/LacD family aldolase 22 207 8.0E-16 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_35380 201f900064489fbee6580ef5ee246a7c 238 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 6 220 31.842 T 12-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 AFR_35380 201f900064489fbee6580ef5ee246a7c 238 SMART SM01133 7 218 3.6E-79 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_30375 85510329a3ca3ed4ee7001ffd2427a94 335 SUPERFAMILY SSF56601 41 308 8.98E-26 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_30375 85510329a3ca3ed4ee7001ffd2427a94 335 Gene3D G3DSA:3.40.710.10 183 310 3.1E-14 T 12-10-2018 AFR_30375 85510329a3ca3ed4ee7001ffd2427a94 335 Gene3D G3DSA:3.40.710.10 34 182 3.1E-18 T 12-10-2018 AFR_30375 85510329a3ca3ed4ee7001ffd2427a94 335 Pfam PF13354 Beta-lactamase enzyme family 74 271 1.1E-31 T 12-10-2018 AFR_04315 9372e5494634cc6a2ce513bede074ea0 331 SUPERFAMILY SSF51679 1 325 1.96E-74 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_04315 9372e5494634cc6a2ce513bede074ea0 331 Pfam PF00296 Luciferase-like monooxygenase 11 301 5.8E-40 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_04315 9372e5494634cc6a2ce513bede074ea0 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 1 326 2.6E-116 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 AFR_04315 9372e5494634cc6a2ce513bede074ea0 331 Gene3D G3DSA:3.20.20.30 1 331 8.8E-93 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_35875 a00bfd65e2231cdb444d975979225ba0 341 SUPERFAMILY SSF160964 13 53 1.57E-5 T 12-10-2018 AFR_35875 a00bfd65e2231cdb444d975979225ba0 341 SUPERFAMILY SSF161098 65 333 8.5E-53 T 12-10-2018 IPR035906 MetI-like superfamily AFR_35875 a00bfd65e2231cdb444d975979225ba0 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 335 5.3E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_09555 81e40d0f7ffde4cb364ebbf1fdb76c01 316 Pfam PF00480 ROK family 4 315 1.2E-75 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_09555 81e40d0f7ffde4cb364ebbf1fdb76c01 316 Gene3D G3DSA:3.30.420.40 124 297 2.5E-96 T 12-10-2018 AFR_09555 81e40d0f7ffde4cb364ebbf1fdb76c01 316 SUPERFAMILY SSF53067 4 315 3.89E-58 T 12-10-2018 AFR_09555 81e40d0f7ffde4cb364ebbf1fdb76c01 316 Gene3D G3DSA:3.30.420.40 5 310 2.5E-96 T 12-10-2018 AFR_09555 81e40d0f7ffde4cb364ebbf1fdb76c01 316 ProSitePatterns PS01125 ROK family signature. 133 160 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_09555 81e40d0f7ffde4cb364ebbf1fdb76c01 316 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 314 1.3E-83 T 12-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 AFR_08880 f8773b93117b5bcdfd06cb0029cb2aab 409 SUPERFAMILY SSF47413 6 70 3.49E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_08880 f8773b93117b5bcdfd06cb0029cb2aab 409 Pfam PF13560 Helix-turn-helix domain 6 64 3.0E-9 T 12-10-2018 AFR_08880 f8773b93117b5bcdfd06cb0029cb2aab 409 SUPERFAMILY SSF48452 156 370 9.05E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_08880 f8773b93117b5bcdfd06cb0029cb2aab 409 SMART SM00530 9 65 3.4E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_08880 f8773b93117b5bcdfd06cb0029cb2aab 409 Gene3D G3DSA:1.10.260.40 6 101 2.5E-11 T 12-10-2018 AFR_26200 32f2a3cda3078c9c8e37ba56ed96be5d 413 Pfam PF07730 Histidine kinase 224 290 7.4E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_26200 32f2a3cda3078c9c8e37ba56ed96be5d 413 Gene3D G3DSA:3.30.565.10 290 411 1.2E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26200 32f2a3cda3078c9c8e37ba56ed96be5d 413 SUPERFAMILY SSF55874 306 410 2.11E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26200 32f2a3cda3078c9c8e37ba56ed96be5d 413 Pfam PF13796 Putative sensor 29 196 2.4E-33 T 12-10-2018 IPR025828 Putative sensor domain AFR_23635 4ff507e6e8cb917d085de78cf6a753ac 560 SUPERFAMILY SSF90123 11 315 1.83E-51 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_23635 4ff507e6e8cb917d085de78cf6a753ac 560 SUPERFAMILY SSF52540 339 557 1.45E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_23635 4ff507e6e8cb917d085de78cf6a753ac 560 Gene3D G3DSA:1.20.1560.10 5 318 2.0E-52 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_23635 4ff507e6e8cb917d085de78cf6a753ac 560 Gene3D G3DSA:3.40.50.300 326 559 1.9E-49 T 12-10-2018 AFR_23635 4ff507e6e8cb917d085de78cf6a753ac 560 ProSitePatterns PS00211 ABC transporters family signature. 463 477 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_23635 4ff507e6e8cb917d085de78cf6a753ac 560 Pfam PF00664 ABC transporter transmembrane region 20 288 4.4E-27 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFR_23635 4ff507e6e8cb917d085de78cf6a753ac 560 Pfam PF00005 ABC transporter 344 490 2.6E-11 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_42990 1989ef059cba93093521b2b8d23fe7e8 79 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 69 1.7E-26 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_42990 1989ef059cba93093521b2b8d23fe7e8 79 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 13 65 3.0E-16 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_42990 1989ef059cba93093521b2b8d23fe7e8 79 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 66 22.438 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_42990 1989ef059cba93093521b2b8d23fe7e8 79 Pfam PF01809 Haemolytic domain 2 65 7.9E-28 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_42990 1989ef059cba93093521b2b8d23fe7e8 79 SMART SM01234 1 65 7.1E-36 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFR_14305 5401b7f7092a3ce6b0723290fb4bf0ca 384 SUPERFAMILY SSF56601 35 347 3.15E-70 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_14305 5401b7f7092a3ce6b0723290fb4bf0ca 384 Gene3D G3DSA:3.40.710.10 26 376 5.4E-95 T 12-10-2018 AFR_14305 5401b7f7092a3ce6b0723290fb4bf0ca 384 Pfam PF00144 Beta-lactamase 51 347 2.4E-51 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_24210 23291ce7abb6e3b3803cd1191e2e7393 773 Pfam PF02687 FtsX-like permease family 677 767 1.5E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_24210 23291ce7abb6e3b3803cd1191e2e7393 773 Pfam PF02687 FtsX-like permease family 250 314 1.6E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_17990 396d690f23bf50e269d71d311fb365c5 308 Gene3D G3DSA:1.10.3720.10 64 297 9.6E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_17990 396d690f23bf50e269d71d311fb365c5 308 SUPERFAMILY SSF161098 67 290 2.75E-50 T 12-10-2018 IPR035906 MetI-like superfamily AFR_17990 396d690f23bf50e269d71d311fb365c5 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 293 4.0E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_28435 c0c4d0d112c9a5dc304b2b22b07d2394 129 SUPERFAMILY SSF50346 9 118 8.83E-20 T 12-10-2018 IPR011033 PRC-barrel-like superfamily AFR_28435 c0c4d0d112c9a5dc304b2b22b07d2394 129 Pfam PF05239 PRC-barrel domain 17 85 5.4E-6 T 12-10-2018 IPR027275 PRC-barrel domain AFR_28435 c0c4d0d112c9a5dc304b2b22b07d2394 129 Gene3D G3DSA:3.90.50.10 9 125 1.3E-9 T 12-10-2018 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 AFR_00115 012810b4927204e287916f2423810a53 257 Gene3D G3DSA:3.40.50.1110 5 192 2.0E-24 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_00115 012810b4927204e287916f2423810a53 257 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 8 180 1.3E-25 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_00115 012810b4927204e287916f2423810a53 257 SUPERFAMILY SSF52266 3 191 3.0E-32 T 12-10-2018 AFR_22380 368708803f09c66ae8048c0d4423b56d 265 Pfam PF01636 Phosphotransferase enzyme family 110 174 2.1E-11 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_22380 368708803f09c66ae8048c0d4423b56d 265 Gene3D G3DSA:3.90.1200.10 79 206 2.0E-10 T 12-10-2018 AFR_22380 368708803f09c66ae8048c0d4423b56d 265 SUPERFAMILY SSF56112 12 207 4.65E-21 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_02750 1b975df76bd7355126513256120468e3 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02750 1b975df76bd7355126513256120468e3 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02750 1b975df76bd7355126513256120468e3 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02750 1b975df76bd7355126513256120468e3 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.3E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02750 1b975df76bd7355126513256120468e3 179 SUPERFAMILY SSF46785 9 143 3.02E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_02750 1b975df76bd7355126513256120468e3 179 Gene3D G3DSA:1.10.10.10 1 155 6.8E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02750 1b975df76bd7355126513256120468e3 179 SMART SM00347 26 129 6.0E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02750 1b975df76bd7355126513256120468e3 179 Pfam PF12802 MarR family 32 92 2.6E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_02830 bfc5052f94365590b210e71b2f163ee9 128 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 12 118 3.3E-19 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFR_02830 bfc5052f94365590b210e71b2f163ee9 128 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 10 123 16.991 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFR_29680 7f2516313bf117b38ba3d6006b9ab56c 253 SMART SM00471 38 133 9.2E-8 T 12-10-2018 IPR003607 HD/PDEase domain AFR_29680 7f2516313bf117b38ba3d6006b9ab56c 253 Pfam PF13328 HD domain 23 153 4.1E-22 T 12-10-2018 IPR003607 HD/PDEase domain AFR_29680 7f2516313bf117b38ba3d6006b9ab56c 253 SUPERFAMILY SSF109604 4 169 1.06E-42 T 12-10-2018 AFR_29680 7f2516313bf117b38ba3d6006b9ab56c 253 Gene3D G3DSA:1.10.3210.10 2 171 1.1E-44 T 12-10-2018 AFR_30275 3d3dc572c2781ade146c9f3976431240 234 Pfam PF11139 Sap, sulfolipid-1-addressing protein 10 225 2.4E-25 T 12-10-2018 IPR021315 Glycolipid exporter Gap/Sap AFR_39890 cb28288970936ab668cbd0767abfe50a 212 Gene3D G3DSA:3.40.630.30 15 194 2.5E-42 T 12-10-2018 AFR_39890 cb28288970936ab668cbd0767abfe50a 212 SUPERFAMILY SSF55729 11 190 2.51E-38 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_39890 cb28288970936ab668cbd0767abfe50a 212 Pfam PF13302 Acetyltransferase (GNAT) domain 17 166 6.5E-19 T 12-10-2018 IPR000182 GNAT domain AFR_21620 99af85f1eeba35b8379cbb5cb47e7f99 90 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 12 56 6.7E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_21620 99af85f1eeba35b8379cbb5cb47e7f99 90 Gene3D G3DSA:3.40.50.1000 4 90 1.4E-20 T 12-10-2018 IPR023214 HAD superfamily AFR_21620 99af85f1eeba35b8379cbb5cb47e7f99 90 Pfam PF13242 HAD-hyrolase-like 18 78 5.9E-12 T 12-10-2018 AFR_21620 99af85f1eeba35b8379cbb5cb47e7f99 90 SUPERFAMILY SSF56784 9 89 7.91E-21 T 12-10-2018 IPR036412 HAD-like superfamily AFR_13935 cad7de05857883fb260dedfc48ba8573 372 Pfam PF01494 FAD binding domain 5 309 1.3E-20 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_13935 cad7de05857883fb260dedfc48ba8573 372 SUPERFAMILY SSF51905 5 353 1.88E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13935 cad7de05857883fb260dedfc48ba8573 372 Gene3D G3DSA:3.50.50.60 5 347 1.2E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13935 cad7de05857883fb260dedfc48ba8573 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 1.2E-19 T 12-10-2018 AFR_13935 cad7de05857883fb260dedfc48ba8573 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 1.2E-19 T 12-10-2018 AFR_13935 cad7de05857883fb260dedfc48ba8573 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.2E-19 T 12-10-2018 AFR_13935 cad7de05857883fb260dedfc48ba8573 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.2E-19 T 12-10-2018 AFR_02430 9c00f7cbe3c83e84b70ae4c1e902879a 125 Pfam PF04134 Protein of unknown function, DUF393 7 113 7.1E-13 T 12-10-2018 IPR007263 Protein of unknown function DUF393 AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 Pfam PF01327 Polypeptide deformylase 4 147 1.2E-33 T 12-10-2018 IPR023635 Peptide deformylase AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 PIRSF PIRSF004749 1 165 2.9E-37 T 12-10-2018 IPR023635 Peptide deformylase AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 PRINTS PR01576 Peptide deformylase signature 98 116 1.6E-24 T 12-10-2018 IPR023635 Peptide deformylase AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 PRINTS PR01576 Peptide deformylase signature 86 97 1.6E-24 T 12-10-2018 IPR023635 Peptide deformylase AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 PRINTS PR01576 Peptide deformylase signature 33 62 1.6E-24 T 12-10-2018 IPR023635 Peptide deformylase AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 PRINTS PR01576 Peptide deformylase signature 117 146 1.6E-24 T 12-10-2018 IPR023635 Peptide deformylase AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 9 152 4.1E-31 T 12-10-2018 IPR023635 Peptide deformylase AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 Gene3D G3DSA:3.90.45.10 1 164 5.3E-46 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 SUPERFAMILY SSF56420 3 158 7.07E-48 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFR_21225 dff60f6665b295eaac14a90a5a2516cb 165 Hamap MF_00163 Peptide deformylase [def]. 2 159 24.75 T 12-10-2018 IPR023635 Peptide deformylase AFR_10745 74cabe22064e21c16c6b758949bab313 218 SUPERFAMILY SSF48371 8 218 9.35E-52 T 12-10-2018 IPR016024 Armadillo-type fold AFR_10745 74cabe22064e21c16c6b758949bab313 218 Gene3D G3DSA:1.25.10.90 1 218 3.7E-74 T 12-10-2018 AFR_10745 74cabe22064e21c16c6b758949bab313 218 Pfam PF08713 DNA alkylation repair enzyme 7 218 4.2E-62 T 12-10-2018 IPR014825 DNA alkylation repair enzyme AFR_01915 bfb474936ebf1c2b397941576751bc67 183 ProSitePatterns PS01081 TetR-type HTH domain signature. 13 44 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_01915 bfb474936ebf1c2b397941576751bc67 183 Gene3D G3DSA:1.10.357.10 1 182 2.4E-55 T 12-10-2018 AFR_01915 bfb474936ebf1c2b397941576751bc67 183 SUPERFAMILY SSF46689 2 63 4.57E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_01915 bfb474936ebf1c2b397941576751bc67 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 1.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01915 bfb474936ebf1c2b397941576751bc67 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_01915 bfb474936ebf1c2b397941576751bc67 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_30260 18db750b83f83bcf59bf683d5ea73154 248 Gene3D G3DSA:3.30.70.1230 1 123 6.0E-7 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_30260 18db750b83f83bcf59bf683d5ea73154 248 SUPERFAMILY SSF55073 1 121 7.22E-8 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_25050 8bf8368d2b2829387e13db4ef63d153e 393 Gene3D G3DSA:3.60.21.10 165 353 3.5E-16 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_25050 8bf8368d2b2829387e13db4ef63d153e 393 SUPERFAMILY SSF56300 166 391 6.77E-33 T 12-10-2018 AFR_25050 8bf8368d2b2829387e13db4ef63d153e 393 Pfam PF00149 Calcineurin-like phosphoesterase 166 334 1.8E-7 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_39485 4123b9c29b9b9db9228bbb0ed8da85c1 1165 Gene3D G3DSA:3.90.550.10 5 201 3.1E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_39485 4123b9c29b9b9db9228bbb0ed8da85c1 1165 Gene3D G3DSA:3.40.50.12580 964 1143 1.0E-117 T 12-10-2018 AFR_39485 4123b9c29b9b9db9228bbb0ed8da85c1 1165 SUPERFAMILY SSF53756 925 1150 1.1E-14 T 12-10-2018 AFR_39485 4123b9c29b9b9db9228bbb0ed8da85c1 1165 Gene3D G3DSA:3.40.50.11820 803 1150 1.0E-117 T 12-10-2018 AFR_39485 4123b9c29b9b9db9228bbb0ed8da85c1 1165 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 802 1153 3.6E-104 T 12-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 AFR_39485 4123b9c29b9b9db9228bbb0ed8da85c1 1165 Pfam PF00535 Glycosyl transferase family 2 7 134 4.9E-35 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_39485 4123b9c29b9b9db9228bbb0ed8da85c1 1165 SUPERFAMILY SSF53448 6 213 1.22E-49 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23435 f289e2f0fd2b56ae1aea65359ffe2501 287 Gene3D G3DSA:3.30.200.20 1 91 9.3E-12 T 12-10-2018 AFR_23435 f289e2f0fd2b56ae1aea65359ffe2501 287 Pfam PF01636 Phosphotransferase enzyme family 25 247 1.9E-35 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_23435 f289e2f0fd2b56ae1aea65359ffe2501 287 SUPERFAMILY SSF56112 7 257 3.24E-48 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_23435 f289e2f0fd2b56ae1aea65359ffe2501 287 Gene3D G3DSA:3.90.1200.10 108 258 1.3E-15 T 12-10-2018 AFR_08775 cc7ef8be41928d899e71ac942255175d 265 Pfam PF12679 ABC-2 family transporter protein 71 263 2.8E-15 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_32860 d18a06063def0973ecdd96cfc9986d1e 368 Gene3D G3DSA:3.40.50.720 198 351 2.5E-58 T 12-10-2018 AFR_32860 d18a06063def0973ecdd96cfc9986d1e 368 Pfam PF13478 XdhC Rossmann domain 199 345 5.2E-42 T 12-10-2018 IPR027051 XdhC Rossmann domain AFR_32860 d18a06063def0973ecdd96cfc9986d1e 368 Pfam PF02625 XdhC and CoxI family 12 78 4.4E-22 T 12-10-2018 IPR003777 XdhC- CoxI AFR_32860 d18a06063def0973ecdd96cfc9986d1e 368 Pfam PF02625 XdhC and CoxI family 114 176 7.9E-17 T 12-10-2018 IPR003777 XdhC- CoxI AFR_12050 b02a196e44a8d0bc8c66a0655b8696cc 328 Gene3D G3DSA:3.40.50.300 12 209 2.1E-46 T 12-10-2018 AFR_12050 b02a196e44a8d0bc8c66a0655b8696cc 328 PIRSF PIRSF002849 2 321 2.4E-126 T 12-10-2018 AFR_12050 b02a196e44a8d0bc8c66a0655b8696cc 328 SUPERFAMILY SSF52540 20 291 2.76E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12050 b02a196e44a8d0bc8c66a0655b8696cc 328 Gene3D G3DSA:1.10.8.300 210 316 3.0E-28 T 12-10-2018 AFR_12050 b02a196e44a8d0bc8c66a0655b8696cc 328 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 48 178 2.5E-62 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_30875 377ad8739e9f0dc055be23a56696df45 420 SUPERFAMILY SSF53850 16 418 7.76E-70 T 12-10-2018 AFR_30875 377ad8739e9f0dc055be23a56696df45 420 Pfam PF13416 Bacterial extracellular solute-binding protein 59 353 3.2E-30 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_30875 377ad8739e9f0dc055be23a56696df45 420 Gene3D G3DSA:3.40.190.10 57 375 1.5E-76 T 12-10-2018 AFR_30875 377ad8739e9f0dc055be23a56696df45 420 Gene3D G3DSA:3.40.190.10 156 413 1.5E-76 T 12-10-2018 AFR_22675 000f08cdbfcfc7b56fa776dd4cd1ed5c 412 SUPERFAMILY SSF56112 1 240 6.61E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_22675 000f08cdbfcfc7b56fa776dd4cd1ed5c 412 Gene3D G3DSA:1.10.510.10 67 244 3.2E-46 T 12-10-2018 AFR_22675 000f08cdbfcfc7b56fa776dd4cd1ed5c 412 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 109 121 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFR_22675 000f08cdbfcfc7b56fa776dd4cd1ed5c 412 SMART SM00220 1 242 2.1E-47 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_22675 000f08cdbfcfc7b56fa776dd4cd1ed5c 412 Pfam PF00069 Protein kinase domain 2 239 2.6E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_22675 000f08cdbfcfc7b56fa776dd4cd1ed5c 412 Gene3D G3DSA:3.30.200.20 1 66 1.1E-21 T 12-10-2018 AFR_12810 ff7d0c7c8a9cb8588bc30fb15c52d779 161 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 2.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12810 ff7d0c7c8a9cb8588bc30fb15c52d779 161 Gene3D G3DSA:1.10.10.60 1 37 8.7E-15 T 12-10-2018 AFR_12810 ff7d0c7c8a9cb8588bc30fb15c52d779 161 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12810 ff7d0c7c8a9cb8588bc30fb15c52d779 161 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12810 ff7d0c7c8a9cb8588bc30fb15c52d779 161 SUPERFAMILY SSF48498 64 160 2.59E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12810 ff7d0c7c8a9cb8588bc30fb15c52d779 161 Gene3D G3DSA:1.10.357.10 38 160 7.4E-35 T 12-10-2018 AFR_12810 ff7d0c7c8a9cb8588bc30fb15c52d779 161 SUPERFAMILY SSF46689 2 55 3.28E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_04815 23d00af6cc5aa6f60dd461766a9c6edb 467 SUPERFAMILY SSF53474 320 383 4.21E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_04815 23d00af6cc5aa6f60dd461766a9c6edb 467 Pfam PF06259 Alpha/beta hydrolase 216 383 3.7E-34 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 AFR_36090 a67286d5910ed6c035e9c1c0eacf81c2 451 SMART SM00387 328 424 2.6E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_36090 a67286d5910ed6c035e9c1c0eacf81c2 451 SUPERFAMILY SSF55874 300 421 3.29E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_36090 a67286d5910ed6c035e9c1c0eacf81c2 451 Pfam PF07730 Histidine kinase 219 284 7.7E-21 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_36090 a67286d5910ed6c035e9c1c0eacf81c2 451 Gene3D G3DSA:3.30.565.10 293 423 2.1E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41700 68ca1cf3d01e8759a3aa09956c3c41c0 182 SMART SM00418 10 92 6.0E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_41700 68ca1cf3d01e8759a3aa09956c3c41c0 182 Gene3D G3DSA:1.10.10.10 9 121 9.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_41700 68ca1cf3d01e8759a3aa09956c3c41c0 182 Pfam PF12840 Helix-turn-helix domain 11 68 1.1E-11 T 12-10-2018 AFR_41700 68ca1cf3d01e8759a3aa09956c3c41c0 182 SUPERFAMILY SSF46785 10 168 7.14E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_40855 710feb9642d770f6d80aae59a8db3721 89 Pfam PF13223 Protein of unknown function (DUF4031) 2 76 6.2E-29 T 12-10-2018 IPR025109 Domain of unknown function DUF4031 AFR_26955 7c645c65659c703615fb142ed744aa88 416 Gene3D G3DSA:3.40.50.2000 228 396 1.2E-110 T 12-10-2018 AFR_26955 7c645c65659c703615fb142ed744aa88 416 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 239 383 6.1E-5 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 AFR_26955 7c645c65659c703615fb142ed744aa88 416 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 136 9.5E-9 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_26955 7c645c65659c703615fb142ed744aa88 416 SUPERFAMILY SSF53756 1 409 5.65E-90 T 12-10-2018 AFR_26955 7c645c65659c703615fb142ed744aa88 416 Gene3D G3DSA:3.40.50.2000 2 398 1.2E-110 T 12-10-2018 AFR_34760 90fbea039662b4c95af63d6bddc0914f 251 Pfam PF14062 Domain of unknown function (DUF4253) 143 251 2.0E-34 T 12-10-2018 IPR025349 Domain of unknown function DUF4253 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 SUPERFAMILY SSF47384 207 269 2.35E-8 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 Gene3D G3DSA:1.10.287.130 173 278 4.5E-16 T 12-10-2018 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 SUPERFAMILY SSF55874 284 424 9.18E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 SMART SM00304 169 221 1.6E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 1.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 1.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 1.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 Gene3D G3DSA:3.30.565.10 284 422 1.5E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 SMART SM00388 222 280 0.0027 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 SMART SM00387 324 423 2.8E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_40980 e6f597314e6b076bc97bfebc9645fbd8 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 421 5.3E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_31290 81273f81f77312b8b2915281eaf76408 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 129 1.5E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_31290 81273f81f77312b8b2915281eaf76408 140 Gene3D G3DSA:3.30.720.110 81 139 4.7E-16 T 12-10-2018 AFR_31290 81273f81f77312b8b2915281eaf76408 140 Gene3D G3DSA:3.30.720.120 11 73 3.1E-8 T 12-10-2018 AFR_31290 81273f81f77312b8b2915281eaf76408 140 SUPERFAMILY SSF54593 13 132 9.67E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 SUPERFAMILY SSF52172 1 181 9.11E-54 T 12-10-2018 IPR011006 CheY-like superfamily AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 SMART SM01012 126 181 3.8E-23 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 Gene3D G3DSA:1.10.10.10 128 187 2.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 SMART SM00448 1 110 4.3E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 PIRSF PIRSF036382 1 187 3.3E-65 T 12-10-2018 IPR008327 Signal transduction response regulator, antiterminator AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 Pfam PF03861 ANTAR domain 130 181 2.4E-20 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 Pfam PF00072 Response regulator receiver domain 1 110 7.7E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_10385 a39de388ac1b912fcdcd5abe37493239 193 Gene3D G3DSA:3.40.50.2300 1 127 2.2E-35 T 12-10-2018 AFR_30890 2e5f9182f1d001ab433989df2cc25a40 409 Gene3D G3DSA:3.20.20.140 52 306 1.3E-106 T 12-10-2018 AFR_30890 2e5f9182f1d001ab433989df2cc25a40 409 Gene3D G3DSA:2.30.40.10 7 351 1.3E-106 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_30890 2e5f9182f1d001ab433989df2cc25a40 409 SUPERFAMILY SSF51338 3 329 2.16E-14 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_30890 2e5f9182f1d001ab433989df2cc25a40 409 Pfam PF01979 Amidohydrolase family 247 319 1.1E-8 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_30890 2e5f9182f1d001ab433989df2cc25a40 409 SUPERFAMILY SSF51556 52 304 4.69E-50 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_00650 0e755ff7b41a108138a103acee0a0247 397 SUPERFAMILY SSF102405 172 392 1.95E-18 T 12-10-2018 AFR_33760 81f5d45aeb2378bac02c812ded047df8 114 Pfam PF10517 Electron transfer DM13 8 112 8.6E-31 T 12-10-2018 IPR019545 DM13 domain AFR_40485 60cfe9b8c1411d5b3f927140cfca9b32 262 Pfam PF01618 MotA/TolQ/ExbB proton channel family 101 219 5.5E-25 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFR_40485 60cfe9b8c1411d5b3f927140cfca9b32 262 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 185 202 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site AFR_06765 c6318434d70035f72ce1ee0fd5a1ab96 225 SUPERFAMILY SSF50800 5 224 4.71E-20 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_06765 c6318434d70035f72ce1ee0fd5a1ab96 225 Pfam PF03476 MOSC N-terminal beta barrel domain 5 69 1.0E-9 T 12-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 AFR_06765 c6318434d70035f72ce1ee0fd5a1ab96 225 Pfam PF03473 MOSC domain 106 223 3.8E-11 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 AFR_06765 c6318434d70035f72ce1ee0fd5a1ab96 225 Gene3D G3DSA:2.40.33.20 89 225 8.5E-7 T 12-10-2018 AFR_14875 5d06e5dec31765be11fbd1a5725d5c02 280 SMART SM00342 182 264 5.6E-5 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_14875 5d06e5dec31765be11fbd1a5725d5c02 280 Gene3D G3DSA:1.10.10.60 175 266 2.6E-14 T 12-10-2018 AFR_14875 5d06e5dec31765be11fbd1a5725d5c02 280 Pfam PF12833 Helix-turn-helix domain 188 263 8.4E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_20400 fdb65062f6f9cb491810be6e35b7147d 385 SUPERFAMILY SSF53822 37 378 2.04E-79 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_20400 fdb65062f6f9cb491810be6e35b7147d 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 61 77 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_20400 fdb65062f6f9cb491810be6e35b7147d 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 80 98 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_20400 fdb65062f6f9cb491810be6e35b7147d 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 343 358 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_20400 fdb65062f6f9cb491810be6e35b7147d 385 Gene3D G3DSA:3.40.50.2300 46 358 2.6E-80 T 12-10-2018 AFR_20400 fdb65062f6f9cb491810be6e35b7147d 385 Gene3D G3DSA:3.40.50.2300 157 286 2.6E-80 T 12-10-2018 AFR_20400 fdb65062f6f9cb491810be6e35b7147d 385 Pfam PF13458 Periplasmic binding protein 39 372 2.4E-60 T 12-10-2018 IPR028081 Leucine-binding protein domain AFR_41985 7036c487ea6102b8fe53d1780ad6b2ef 448 SUPERFAMILY SSF53448 59 307 1.78E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_41985 7036c487ea6102b8fe53d1780ad6b2ef 448 Gene3D G3DSA:3.90.550.10 53 274 7.4E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_41985 7036c487ea6102b8fe53d1780ad6b2ef 448 Pfam PF13641 Glycosyltransferase like family 2 54 291 1.0E-27 T 12-10-2018 AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 SUPERFAMILY SSF52374 2 131 5.63E-24 T 12-10-2018 AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 128 1.3E-33 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 1 19 2.5E-18 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 2.5E-18 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 19 40 2.5E-18 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 Pfam PF01467 Cytidylyltransferase-like 4 110 8.9E-12 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 Gene3D G3DSA:3.40.50.620 1 132 2.0E-32 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_29790 35f71674886b8cbc88e4bc9c2dd95763 133 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 62 2.0E-15 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFR_07470 4316d68f5cede4928610203f584e18f7 208 SUPERFAMILY SSF52833 6 168 1.45E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_07470 4316d68f5cede4928610203f584e18f7 208 Gene3D G3DSA:3.40.30.10 6 208 9.9E-68 T 12-10-2018 AFR_08745 6f2f914ab863e0fbe32371aa5f9f640f 417 Gene3D G3DSA:1.20.1250.20 19 213 6.6E-15 T 12-10-2018 AFR_08745 6f2f914ab863e0fbe32371aa5f9f640f 417 Gene3D G3DSA:1.20.1250.20 228 415 1.3E-24 T 12-10-2018 AFR_08745 6f2f914ab863e0fbe32371aa5f9f640f 417 SUPERFAMILY SSF103473 21 414 2.49E-44 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_08745 6f2f914ab863e0fbe32371aa5f9f640f 417 Pfam PF07690 Major Facilitator Superfamily 254 411 1.7E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_28030 4f7f08ad071cabc1efdfb0e15cd018dd 295 SUPERFAMILY SSF51679 1 285 5.0E-41 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_28030 4f7f08ad071cabc1efdfb0e15cd018dd 295 Gene3D G3DSA:3.20.20.30 1 294 1.1E-53 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_28030 4f7f08ad071cabc1efdfb0e15cd018dd 295 Pfam PF00296 Luciferase-like monooxygenase 10 274 1.3E-30 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_28995 ad9e5283dd83b788378992ab8a473584 270 Gene3D G3DSA:1.50.10.150 1 259 9.1E-62 T 12-10-2018 IPR038665 Voltage-dependent anion channel superfamily AFR_28995 ad9e5283dd83b788378992ab8a473584 270 Pfam PF03595 Voltage-dependent anion channel 3 245 4.0E-21 T 12-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 AFR_04140 606e45371e7b87775eb4d68587d57510 393 Pfam PF11350 Protein of unknown function (DUF3152) 208 372 1.2E-35 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 AFR_04140 606e45371e7b87775eb4d68587d57510 393 SUPERFAMILY SSF55486 247 372 1.19E-11 T 12-10-2018 AFR_10735 99d061387886eee1584cc880b82c3335 231 PIRSF PIRSF000709 6 185 8.8E-11 T 12-10-2018 AFR_10735 99d061387886eee1584cc880b82c3335 231 SMART SM00855 6 180 1.9E-18 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_10735 99d061387886eee1584cc880b82c3335 231 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 AFR_10735 99d061387886eee1584cc880b82c3335 231 Gene3D G3DSA:3.40.50.1240 3 230 1.6E-44 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_10735 99d061387886eee1584cc880b82c3335 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 223 7.4E-41 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_10735 99d061387886eee1584cc880b82c3335 231 SUPERFAMILY SSF53254 6 229 3.47E-48 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_15805 66e07cc965c66716ef6f298520f9036d 382 SUPERFAMILY SSF54060 162 375 6.83E-54 T 12-10-2018 AFR_15805 66e07cc965c66716ef6f298520f9036d 382 Pfam PF04231 Endonuclease I 166 375 1.4E-35 T 12-10-2018 IPR007346 Endonuclease I GO:0004518 AFR_12985 72a268f53ec515733f5ed69496db7521 241 Gene3D G3DSA:3.40.50.720 2 239 2.8E-69 T 12-10-2018 AFR_12985 72a268f53ec515733f5ed69496db7521 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 237 7.5E-59 T 12-10-2018 AFR_12985 72a268f53ec515733f5ed69496db7521 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12985 72a268f53ec515733f5ed69496db7521 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12985 72a268f53ec515733f5ed69496db7521 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12985 72a268f53ec515733f5ed69496db7521 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12985 72a268f53ec515733f5ed69496db7521 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12985 72a268f53ec515733f5ed69496db7521 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12985 72a268f53ec515733f5ed69496db7521 241 SUPERFAMILY SSF51735 4 237 1.83E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13035 94d23a812455ea78087f2447233a7d33 99 Gene3D G3DSA:3.40.50.300 29 99 2.9E-6 T 12-10-2018 AFR_13035 94d23a812455ea78087f2447233a7d33 99 SUPERFAMILY SSF52540 4 93 3.06E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13535 755b0ca9f8167b224727a4152ff65b3e 275 Gene3D G3DSA:1.10.260.40 28 80 9.7E-7 T 12-10-2018 AFR_13535 755b0ca9f8167b224727a4152ff65b3e 275 Gene3D G3DSA:3.30.450.180 103 262 3.0E-9 T 12-10-2018 AFR_13535 755b0ca9f8167b224727a4152ff65b3e 275 Pfam PF13560 Helix-turn-helix domain 5 84 7.4E-17 T 12-10-2018 AFR_13535 755b0ca9f8167b224727a4152ff65b3e 275 SUPERFAMILY SSF47413 30 79 6.26E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_13535 755b0ca9f8167b224727a4152ff65b3e 275 SMART SM00530 9 81 1.3E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_18805 dff508dc11d7d184e418d6f0e81da329 276 SUPERFAMILY SSF81345 4 261 3.53E-25 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_18805 dff508dc11d7d184e418d6f0e81da329 276 Gene3D G3DSA:1.10.3470.10 33 268 1.7E-6 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_18805 dff508dc11d7d184e418d6f0e81da329 276 Pfam PF00950 ABC 3 transport family 5 257 4.5E-53 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFR_23320 05b265179ca580ac9f1f9f56436174cd 362 SUPERFAMILY SSF53756 44 351 2.2E-17 T 12-10-2018 AFR_23320 05b265179ca580ac9f1f9f56436174cd 362 Gene3D G3DSA:3.40.50.2000 163 338 2.8E-7 T 12-10-2018 AFR_23320 05b265179ca580ac9f1f9f56436174cd 362 Pfam PF13439 Glycosyltransferase Family 4 36 150 3.3E-7 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_23320 05b265179ca580ac9f1f9f56436174cd 362 Gene3D G3DSA:3.40.50.2000 9 154 1.2E-8 T 12-10-2018 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 SUPERFAMILY SSF49384 508 610 8.37E-12 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 Gene3D G3DSA:3.30.200.20 5 100 7.4E-32 T 12-10-2018 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 Gene3D G3DSA:2.60.40.290 507 612 3.5E-15 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 Gene3D G3DSA:1.10.510.10 101 284 1.8E-44 T 12-10-2018 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 SUPERFAMILY SSF56112 13 277 3.64E-69 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_30945 0880f6d0d485088dff701ca38a66f018 752 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 140 152 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 Pfam PF00069 Protein kinase domain 16 271 5.9E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 SMART SM00637 513 610 1.1E-5 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_30945 0880f6d0d485088dff701ca38a66f018 752 Pfam PF00553 Cellulose binding domain 513 610 1.3E-9 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_41230 3749fbf3a23c3ec1a7abee983570269c 382 Pfam PF00480 ROK family 83 362 3.2E-26 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFR_41230 3749fbf3a23c3ec1a7abee983570269c 382 Gene3D G3DSA:3.30.420.40 204 352 1.4E-23 T 12-10-2018 AFR_41230 3749fbf3a23c3ec1a7abee983570269c 382 SUPERFAMILY SSF46785 2 62 1.39E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_41230 3749fbf3a23c3ec1a7abee983570269c 382 Gene3D G3DSA:3.30.420.40 66 203 9.9E-19 T 12-10-2018 AFR_41230 3749fbf3a23c3ec1a7abee983570269c 382 Gene3D G3DSA:1.10.10.10 1 60 4.6E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_41230 3749fbf3a23c3ec1a7abee983570269c 382 SUPERFAMILY SSF53067 83 364 2.05E-32 T 12-10-2018 AFR_03000 3f763b11d561202996941e1ba7f9289f 484 Gene3D G3DSA:1.20.1250.20 267 473 7.4E-19 T 12-10-2018 AFR_03000 3f763b11d561202996941e1ba7f9289f 484 Gene3D G3DSA:1.20.1720.10 9 215 3.1E-44 T 12-10-2018 AFR_03000 3f763b11d561202996941e1ba7f9289f 484 Pfam PF07690 Major Facilitator Superfamily 12 407 6.1E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_03000 3f763b11d561202996941e1ba7f9289f 484 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 419 2.3E-77 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_03000 3f763b11d561202996941e1ba7f9289f 484 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_03000 3f763b11d561202996941e1ba7f9289f 484 SUPERFAMILY SSF103473 2 468 1.16E-66 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_00840 ebcd5eaaa9ee0fdeba9ab959d4762114 337 Gene3D G3DSA:3.40.50.1110 47 254 2.8E-57 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_00840 ebcd5eaaa9ee0fdeba9ab959d4762114 337 SUPERFAMILY SSF52266 47 238 7.33E-28 T 12-10-2018 AFR_00840 ebcd5eaaa9ee0fdeba9ab959d4762114 337 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 55 227 6.3E-19 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_26475 e76da04b16b3686395c8f33671059302 215 Gene3D G3DSA:3.40.50.1000 1 183 1.2E-49 T 12-10-2018 IPR023214 HAD superfamily AFR_26475 e76da04b16b3686395c8f33671059302 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 180 2.3E-26 T 12-10-2018 AFR_26475 e76da04b16b3686395c8f33671059302 215 SUPERFAMILY SSF56784 1 183 5.22E-47 T 12-10-2018 IPR036412 HAD-like superfamily AFR_26475 e76da04b16b3686395c8f33671059302 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 55 178 3.1E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26475 e76da04b16b3686395c8f33671059302 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 140 4.2E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26475 e76da04b16b3686395c8f33671059302 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 4.2E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26475 e76da04b16b3686395c8f33671059302 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 162 4.2E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_26475 e76da04b16b3686395c8f33671059302 215 Gene3D G3DSA:1.10.150.240 11 81 1.2E-49 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_11785 173dff7a460b8245a36e0ab319b91dc7 182 Pfam PF13302 Acetyltransferase (GNAT) domain 15 152 9.9E-30 T 12-10-2018 IPR000182 GNAT domain AFR_11785 173dff7a460b8245a36e0ab319b91dc7 182 Gene3D G3DSA:3.40.630.30 9 182 2.3E-47 T 12-10-2018 AFR_11785 173dff7a460b8245a36e0ab319b91dc7 182 SUPERFAMILY SSF55729 9 177 9.9E-44 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_07490 c161c21682c245217ed8437e34acc1d9 157 SUPERFAMILY SSF89623 1 151 1.7E-50 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFR_07490 c161c21682c245217ed8437e34acc1d9 157 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 2.4E-63 T 12-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 AFR_07490 c161c21682c245217ed8437e34acc1d9 157 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.1E-51 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFR_07490 c161c21682c245217ed8437e34acc1d9 157 Gene3D G3DSA:3.40.1400.10 1 157 2.2E-58 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFR_07490 c161c21682c245217ed8437e34acc1d9 157 Pfam PF02502 Ribose/Galactose Isomerase 3 142 4.0E-45 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFR_07490 c161c21682c245217ed8437e34acc1d9 157 PIRSF PIRSF005384 1 149 3.9E-49 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFR_31090 ef47376ab187a7c65d9d67e555cc9da8 298 Gene3D G3DSA:3.20.20.70 5 298 8.1E-151 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_31090 ef47376ab187a7c65d9d67e555cc9da8 298 ProSitePatterns PS01235 PdxS/SNZ family signature. 209 227 - T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31090 ef47376ab187a7c65d9d67e555cc9da8 298 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 13 298 2.2E-142 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31090 ef47376ab187a7c65d9d67e555cc9da8 298 Pfam PF01680 SOR/SNZ family 11 216 1.1E-106 T 12-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31090 ef47376ab187a7c65d9d67e555cc9da8 298 PIRSF PIRSF029271 2 298 1.8E-149 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31090 ef47376ab187a7c65d9d67e555cc9da8 298 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 8 298 52.879 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFR_31090 ef47376ab187a7c65d9d67e555cc9da8 298 SUPERFAMILY SSF51366 22 271 1.98E-60 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_09560 acfeb2abead50ce82955020c491c3430 228 Gene3D G3DSA:3.60.10.10 5 228 4.3E-35 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_09560 acfeb2abead50ce82955020c491c3430 228 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 9 216 2.4E-8 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_09560 acfeb2abead50ce82955020c491c3430 228 SUPERFAMILY SSF56219 3 226 1.44E-31 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_39755 ffa10d132cb3e3acce5b081c70bce05a 100 Pfam PF00550 Phosphopantetheine attachment site 12 75 3.9E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFR_39755 ffa10d132cb3e3acce5b081c70bce05a 100 SUPERFAMILY SSF47336 4 93 1.16E-11 T 12-10-2018 IPR036736 ACP-like superfamily AFR_39755 ffa10d132cb3e3acce5b081c70bce05a 100 Gene3D G3DSA:1.10.1200.10 1 99 1.1E-11 T 12-10-2018 IPR036736 ACP-like superfamily AFR_38535 79fa4c5eef16d7b051e2e29e51be4ae9 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_38535 79fa4c5eef16d7b051e2e29e51be4ae9 284 SUPERFAMILY SSF46785 4 110 3.13E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_38535 79fa4c5eef16d7b051e2e29e51be4ae9 284 Gene3D G3DSA:1.10.10.10 1 81 1.5E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_38535 79fa4c5eef16d7b051e2e29e51be4ae9 284 Pfam PF03466 LysR substrate binding domain 88 279 3.2E-15 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_38535 79fa4c5eef16d7b051e2e29e51be4ae9 284 Gene3D G3DSA:3.40.190.290 88 284 2.2E-67 T 12-10-2018 AFR_38535 79fa4c5eef16d7b051e2e29e51be4ae9 284 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 2 282 2.8E-102 T 12-10-2018 IPR017685 HTH-type transcriptional regulator ArgP AFR_38535 79fa4c5eef16d7b051e2e29e51be4ae9 284 SUPERFAMILY SSF53850 87 280 6.7E-21 T 12-10-2018 AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 PRINTS PR00956 Flagellar motor switch protein FliN signature 218 233 7.6E-27 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 PRINTS PR00956 Flagellar motor switch protein FliN signature 205 218 7.6E-27 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 PRINTS PR00956 Flagellar motor switch protein FliN signature 172 188 7.6E-27 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 PRINTS PR00956 Flagellar motor switch protein FliN signature 189 205 7.6E-27 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 170 243 3.0E-30 T 12-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 172 242 1.9E-27 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 Gene3D G3DSA:2.30.330.10 163 247 7.7E-34 T 12-10-2018 IPR036429 SpoA-like superfamily AFR_40505 7dc12096c51c0bdbdf5c0a5fbf188ecf 248 SUPERFAMILY SSF101801 170 245 3.27E-24 T 12-10-2018 IPR036429 SpoA-like superfamily AFR_28540 b316bef5a71643be72e470e68c2da7d3 304 SMART SM00829 10 299 1.0E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_28540 b316bef5a71643be72e470e68c2da7d3 304 Gene3D G3DSA:3.40.50.720 128 253 2.5E-69 T 12-10-2018 AFR_28540 b316bef5a71643be72e470e68c2da7d3 304 SUPERFAMILY SSF50129 4 147 1.67E-39 T 12-10-2018 IPR011032 GroES-like superfamily AFR_28540 b316bef5a71643be72e470e68c2da7d3 304 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 3.0E-10 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_28540 b316bef5a71643be72e470e68c2da7d3 304 Gene3D G3DSA:3.90.180.10 8 297 2.5E-69 T 12-10-2018 AFR_28540 b316bef5a71643be72e470e68c2da7d3 304 SUPERFAMILY SSF51735 117 234 1.85E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13405 96c39bbd4a3f283f5244bd02c626a38e 61 SUPERFAMILY SSF51735 10 58 1.76E-15 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13405 96c39bbd4a3f283f5244bd02c626a38e 61 Gene3D G3DSA:3.40.50.720 2 60 1.1E-14 T 12-10-2018 AFR_13405 96c39bbd4a3f283f5244bd02c626a38e 61 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 57 4.2E-14 T 12-10-2018 AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 SMART SM00487 16 233 2.7E-35 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 Pfam PF08494 DEAD/H associated 664 852 4.2E-74 T 12-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 Gene3D G3DSA:3.40.50.300 6 221 1.5E-57 T 12-10-2018 AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 Pfam PF00270 DEAD/DEAH box helicase 21 204 4.2E-25 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 SUPERFAMILY SSF52540 31 408 1.63E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 SMART SM00490 317 403 5.0E-12 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 SMART SM00382 33 390 8.8E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 Gene3D G3DSA:3.40.50.300 260 419 9.8E-27 T 12-10-2018 AFR_35740 d55f055273a66dedfa9426f5b7933d0d 1510 Pfam PF00271 Helicase conserved C-terminal domain 278 403 7.4E-13 T 12-10-2018 IPR001650 Helicase, C-terminal AFR_08975 7f279c0df9897187f65349484815b947 179 SUPERFAMILY SSF81301 2 118 8.5E-10 T 12-10-2018 AFR_08975 7f279c0df9897187f65349484815b947 179 Gene3D G3DSA:1.20.120.330 126 179 1.1E-10 T 12-10-2018 AFR_08975 7f279c0df9897187f65349484815b947 179 Gene3D G3DSA:3.30.460.10 3 123 6.4E-28 T 12-10-2018 AFR_24660 f68bfa8bb77f71d55b1aa6b0745b3416 337 Pfam PF13228 Domain of unknown function (DUF4037) 96 194 1.6E-28 T 12-10-2018 IPR025117 Domain of unknown function DUF4037 AFR_18060 2b452c73e40ba268a8bf54f2a775b319 345 Pfam PF12849 PBP superfamily domain 28 315 2.0E-51 T 12-10-2018 IPR024370 PBP domain AFR_18060 2b452c73e40ba268a8bf54f2a775b319 345 SUPERFAMILY SSF53850 35 345 1.66E-74 T 12-10-2018 AFR_18060 2b452c73e40ba268a8bf54f2a775b319 345 Gene3D G3DSA:3.40.190.10 114 290 1.9E-95 T 12-10-2018 AFR_18060 2b452c73e40ba268a8bf54f2a775b319 345 PIRSF PIRSF002756 2 345 1.5E-103 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFR_18060 2b452c73e40ba268a8bf54f2a775b319 345 Gene3D G3DSA:3.40.190.10 39 332 1.9E-95 T 12-10-2018 AFR_18060 2b452c73e40ba268a8bf54f2a775b319 345 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 35 343 1.2E-76 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFR_02085 fbbff2b81e4c22a8851bec358856ef38 811 Pfam PF13625 Helicase conserved C-terminal domain 513 635 2.4E-40 T 12-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 AFR_38835 a5107c6fc52a8df1be2ca1bc68e4a139 351 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 316 349 6.8E-5 T 12-10-2018 AFR_05180 35256b4dae7a0e62b05dd4ef040650bf 242 Gene3D G3DSA:3.40.50.150 12 211 6.1E-16 T 12-10-2018 AFR_05180 35256b4dae7a0e62b05dd4ef040650bf 242 SUPERFAMILY SSF53335 13 203 4.17E-14 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_05180 35256b4dae7a0e62b05dd4ef040650bf 242 Pfam PF13489 Methyltransferase domain 53 197 7.0E-7 T 12-10-2018 AFR_19080 a3dea12f5de2401112780b019aa33434 248 Gene3D G3DSA:3.60.21.10 1 247 4.1E-66 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_19080 a3dea12f5de2401112780b019aa33434 248 Pfam PF00149 Calcineurin-like phosphoesterase 2 189 1.5E-15 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_19080 a3dea12f5de2401112780b019aa33434 248 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 2 247 33.905 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 AFR_19080 a3dea12f5de2401112780b019aa33434 248 SUPERFAMILY SSF56300 1 243 3.38E-46 T 12-10-2018 AFR_24095 a6111ca4b4ed03b24d494675c6844daf 267 Pfam PF04672 S-adenosyl methyltransferase 8 267 1.2E-100 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_24095 a6111ca4b4ed03b24d494675c6844daf 267 PIRSF PIRSF017393 2 267 2.5E-98 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_24095 a6111ca4b4ed03b24d494675c6844daf 267 SUPERFAMILY SSF53335 19 249 3.46E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_24095 a6111ca4b4ed03b24d494675c6844daf 267 Gene3D G3DSA:3.40.50.150 1 267 1.5E-98 T 12-10-2018 AFR_24595 23b670365f911660f884758c5ac51e00 365 SUPERFAMILY SSF55874 268 360 1.74E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24595 23b670365f911660f884758c5ac51e00 365 Pfam PF07730 Histidine kinase 162 225 3.3E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_24595 23b670365f911660f884758c5ac51e00 365 Gene3D G3DSA:3.30.565.10 240 362 9.8E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_10860 e420db2930d021a26eb9a4b92ef17468 120 Gene3D G3DSA:3.10.450.50 1 118 4.5E-41 T 12-10-2018 AFR_10860 e420db2930d021a26eb9a4b92ef17468 120 SUPERFAMILY SSF54427 1 116 1.23E-35 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_10860 e420db2930d021a26eb9a4b92ef17468 120 Pfam PF12680 SnoaL-like domain 8 109 5.6E-14 T 12-10-2018 IPR037401 SnoaL-like domain AFR_17140 4b9521e40fc1acf8592738cd08cf0527 167 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 52 139 1.6E-8 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain AFR_33690 a08fdef8049dafa157d8728aadb94bbe 1040 Pfam PF05729 NACHT domain 326 476 1.2E-6 T 12-10-2018 IPR007111 NACHT nucleoside triphosphatase AFR_33690 a08fdef8049dafa157d8728aadb94bbe 1040 Gene3D G3DSA:3.40.50.300 304 457 2.7E-6 T 12-10-2018 AFR_33690 a08fdef8049dafa157d8728aadb94bbe 1040 SMART SM00382 322 466 0.0012 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33690 a08fdef8049dafa157d8728aadb94bbe 1040 SUPERFAMILY SSF52540 306 481 1.71E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39035 2519fd9adb6f2361a3d4f8544941665e 268 Pfam PF08241 Methyltransferase domain 63 150 5.2E-8 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_39035 2519fd9adb6f2361a3d4f8544941665e 268 Gene3D G3DSA:3.40.50.150 48 245 6.3E-17 T 12-10-2018 AFR_39035 2519fd9adb6f2361a3d4f8544941665e 268 SUPERFAMILY SSF53335 37 234 4.62E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_08585 18054696a8c11a94bb6b299a30b8ed8f 109 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 88 9.1E-17 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_08585 18054696a8c11a94bb6b299a30b8ed8f 109 Pfam PF01740 STAS domain 7 88 1.9E-10 T 12-10-2018 IPR002645 STAS domain AFR_08585 18054696a8c11a94bb6b299a30b8ed8f 109 SUPERFAMILY SSF52091 3 89 1.12E-17 T 12-10-2018 IPR036513 STAS domain superfamily AFR_08585 18054696a8c11a94bb6b299a30b8ed8f 109 Gene3D G3DSA:3.30.750.24 1 93 7.8E-19 T 12-10-2018 IPR036513 STAS domain superfamily AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 216 1.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.4E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 176 0.0052 T 12-10-2018 AFR_04050 521db55cd90903e1b372db76476b53e6 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 7 231 1.1E-38 T 12-10-2018 AFR_04050 521db55cd90903e1b372db76476b53e6 236 SUPERFAMILY SSF51735 1 233 1.58E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 3.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 3.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 3.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_04050 521db55cd90903e1b372db76476b53e6 236 Gene3D G3DSA:3.40.50.720 1 234 1.5E-60 T 12-10-2018 AFR_38215 11c3b9d71081bd3105790da3da0898b8 59 Pfam PF14013 MT0933-like antitoxin protein 4 51 1.1E-17 T 12-10-2018 IPR028037 Antitoxin Rv0909/MT0933 AFR_33280 48f04a0560fc5a0b8208e0daa5ced81f 278 SUPERFAMILY SSF56112 2 241 5.78E-32 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_33280 48f04a0560fc5a0b8208e0daa5ced81f 278 Pfam PF01636 Phosphotransferase enzyme family 1 238 2.9E-19 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_33280 48f04a0560fc5a0b8208e0daa5ced81f 278 Gene3D G3DSA:3.30.200.20 1 73 5.0E-8 T 12-10-2018 AFR_33280 48f04a0560fc5a0b8208e0daa5ced81f 278 Gene3D G3DSA:3.90.1200.10 83 257 1.8E-24 T 12-10-2018 AFR_23110 d5ac043915d250bf2bbe09741150ca55 291 SUPERFAMILY SSF53474 16 239 9.4E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23110 d5ac043915d250bf2bbe09741150ca55 291 Gene3D G3DSA:3.40.50.1820 13 283 5.0E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23110 d5ac043915d250bf2bbe09741150ca55 291 Pfam PF12740 Chlorophyllase enzyme 23 137 2.5E-9 T 12-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 AFR_07200 3938a9ae75720d990846fc19e973bb9a 231 Gene3D G3DSA:2.60.120.620 2 231 3.3E-69 T 12-10-2018 AFR_07200 3938a9ae75720d990846fc19e973bb9a 231 Pfam PF10014 2OG-Fe dioxygenase 40 226 3.9E-54 T 12-10-2018 IPR018724 2OG-Fe dioxygenase AFR_16730 2358c4ca9f71a0477fb6e673033a28af 223 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_16730 2358c4ca9f71a0477fb6e673033a28af 223 Gene3D G3DSA:3.40.50.300 3 222 2.8E-61 T 12-10-2018 AFR_16730 2358c4ca9f71a0477fb6e673033a28af 223 SUPERFAMILY SSF52540 6 221 2.34E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16730 2358c4ca9f71a0477fb6e673033a28af 223 SMART SM00382 33 220 3.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_16730 2358c4ca9f71a0477fb6e673033a28af 223 Pfam PF00005 ABC transporter 25 172 2.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_11890 708f328f0f8e3e10d5dc4ee2e79dc1eb 127 SUPERFAMILY SSF54593 1 117 2.19E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_11890 708f328f0f8e3e10d5dc4ee2e79dc1eb 127 Gene3D G3DSA:3.10.180.10 2 126 2.0E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16225 6c7ebf26ca9072a2a16a9462fae7ea84 418 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 401 1.2E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_16430 f9ba85c698988e9e2620dd02395432c5 416 Pfam PF05977 Transmembrane secretion effector 9 401 7.6E-36 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_16430 f9ba85c698988e9e2620dd02395432c5 416 SUPERFAMILY SSF103473 11 401 1.05E-38 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_16430 f9ba85c698988e9e2620dd02395432c5 416 Gene3D G3DSA:1.20.1250.20 10 400 2.0E-31 T 12-10-2018 AFR_08255 f9a48d5269b6043b5dcc1d810295e6eb 226 Gene3D G3DSA:3.40.50.1000 16 214 1.9E-40 T 12-10-2018 IPR023214 HAD superfamily AFR_08255 f9a48d5269b6043b5dcc1d810295e6eb 226 SUPERFAMILY SSF56784 14 222 3.75E-41 T 12-10-2018 IPR036412 HAD-like superfamily AFR_08255 f9a48d5269b6043b5dcc1d810295e6eb 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 199 3.4E-25 T 12-10-2018 AFR_08255 f9a48d5269b6043b5dcc1d810295e6eb 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 99 199 4.2E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_08255 f9a48d5269b6043b5dcc1d810295e6eb 226 Gene3D G3DSA:1.10.150.240 28 95 1.9E-40 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_26260 1d646eca4bed7151d08b607aee84114d 562 Pfam PF00754 F5/8 type C domain 433 545 6.9E-15 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_26260 1d646eca4bed7151d08b607aee84114d 562 Gene3D G3DSA:2.60.120.260 422 561 6.3E-36 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26260 1d646eca4bed7151d08b607aee84114d 562 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 38 220 2.0E-21 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_26260 1d646eca4bed7151d08b607aee84114d 562 SUPERFAMILY SSF49785 422 561 1.7E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_26260 1d646eca4bed7151d08b607aee84114d 562 Gene3D G3DSA:3.40.50.1110 29 238 5.0E-69 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_26260 1d646eca4bed7151d08b607aee84114d 562 SUPERFAMILY SSF52266 26 229 1.68E-34 T 12-10-2018 AFR_26570 d30d0643a3b2b54b32a7142eefc06228 289 SUPERFAMILY SSF159659 4 254 6.28E-84 T 12-10-2018 AFR_26570 d30d0643a3b2b54b32a7142eefc06228 289 Gene3D G3DSA:3.40.50.10900 13 217 5.7E-91 T 12-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily AFR_26570 d30d0643a3b2b54b32a7142eefc06228 289 PIRSF PIRSF028754 6 287 1.7E-96 T 12-10-2018 IPR008492 Protein of unknown function DUF774 AFR_26570 d30d0643a3b2b54b32a7142eefc06228 289 Pfam PF09754 PAC2 family 19 234 6.9E-49 T 12-10-2018 IPR019151 Proteasome assembly chaperone 2 AFR_26570 d30d0643a3b2b54b32a7142eefc06228 289 Gene3D G3DSA:1.10.287.100 218 253 5.7E-91 T 12-10-2018 AFR_40905 a58f590af18e8df6b103d8214579ab28 383 SUPERFAMILY SSF53686 21 364 4.19E-77 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_40905 a58f590af18e8df6b103d8214579ab28 383 TIGRFAM TIGR00260 thrC: threonine synthase 23 356 1.5E-72 T 12-10-2018 IPR004450 Threonine synthase-like AFR_40905 a58f590af18e8df6b103d8214579ab28 383 Gene3D G3DSA:3.40.50.1100 78 177 5.4E-98 T 12-10-2018 AFR_40905 a58f590af18e8df6b103d8214579ab28 383 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 41 350 3.3E-60 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_40905 a58f590af18e8df6b103d8214579ab28 383 Gene3D G3DSA:3.40.50.1100 25 355 5.4E-98 T 12-10-2018 AFR_06800 c2a7e0901a674e4cdac7cffb5a5ead51 391 Gene3D G3DSA:3.40.50.300 133 374 2.4E-56 T 12-10-2018 AFR_06800 c2a7e0901a674e4cdac7cffb5a5ead51 391 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 136 301 7.2E-12 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AFR_06800 c2a7e0901a674e4cdac7cffb5a5ead51 391 SUPERFAMILY SSF52540 135 373 2.24E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_14310 8bc94b85f7031e2190a172480a38f4b2 300 Gene3D G3DSA:2.30.320.10 41 295 7.5E-11 T 12-10-2018 IPR035948 YwqG-like superfamily AFR_14310 8bc94b85f7031e2190a172480a38f4b2 300 SUPERFAMILY SSF103032 46 293 1.96E-18 T 12-10-2018 IPR035948 YwqG-like superfamily AFR_14310 8bc94b85f7031e2190a172480a38f4b2 300 Pfam PF09234 Domain of unknown function (DUF1963) 46 292 1.8E-18 T 12-10-2018 IPR015315 Protein of unknown function DUF1963 AFR_37005 b8d4f521f3102800f3d0e2d02f00df9a 117 SUPERFAMILY SSF54593 1 117 1.65E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_37005 b8d4f521f3102800f3d0e2d02f00df9a 117 Gene3D G3DSA:3.10.180.10 2 117 9.6E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_34710 17226f3ec6da1c17f8e9f2832024fc05 454 Gene3D G3DSA:3.40.190.10 75 402 7.2E-58 T 12-10-2018 AFR_34710 17226f3ec6da1c17f8e9f2832024fc05 454 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 6 452 8.1E-174 T 12-10-2018 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein AFR_34710 17226f3ec6da1c17f8e9f2832024fc05 454 Gene3D G3DSA:3.40.190.10 165 429 7.2E-58 T 12-10-2018 AFR_34710 17226f3ec6da1c17f8e9f2832024fc05 454 Pfam PF13416 Bacterial extracellular solute-binding protein 86 377 2.6E-19 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_34710 17226f3ec6da1c17f8e9f2832024fc05 454 SUPERFAMILY SSF53850 40 450 2.39E-50 T 12-10-2018 AFR_36560 ce9c2afe3bc77145dcb003352211b084 325 PRINTS PR01217 Proline rich extensin signature 154 175 1.3E-9 T 12-10-2018 AFR_36560 ce9c2afe3bc77145dcb003352211b084 325 PRINTS PR01217 Proline rich extensin signature 142 154 1.3E-9 T 12-10-2018 AFR_36560 ce9c2afe3bc77145dcb003352211b084 325 PRINTS PR01217 Proline rich extensin signature 175 191 1.3E-9 T 12-10-2018 AFR_36560 ce9c2afe3bc77145dcb003352211b084 325 Pfam PF00746 LPXTG cell wall anchor motif 285 322 4.3E-7 T 12-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor AFR_36560 ce9c2afe3bc77145dcb003352211b084 325 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 287 320 0.0016 T 12-10-2018 AFR_18335 1f2b6a1631667b5a399c97f33ec761bb 305 Gene3D G3DSA:2.60.120.200 119 304 2.6E-12 T 12-10-2018 AFR_18335 1f2b6a1631667b5a399c97f33ec761bb 305 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 170 296 1.4E-8 T 12-10-2018 AFR_18335 1f2b6a1631667b5a399c97f33ec761bb 305 SUPERFAMILY SSF49899 120 300 1.98E-14 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_01135 bd19cb4b0f02f1442a349c99239e15b3 453 SMART SM00283 67 321 4.3E-35 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_01135 bd19cb4b0f02f1442a349c99239e15b3 453 Gene3D G3DSA:1.10.287.950 29 308 5.7E-47 T 12-10-2018 AFR_01135 bd19cb4b0f02f1442a349c99239e15b3 453 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 142 297 2.4E-29 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_01135 bd19cb4b0f02f1442a349c99239e15b3 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 165 192 5.3E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_01135 bd19cb4b0f02f1442a349c99239e15b3 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 194 223 5.3E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_01135 bd19cb4b0f02f1442a349c99239e15b3 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 84 113 5.3E-19 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_01135 bd19cb4b0f02f1442a349c99239e15b3 453 SUPERFAMILY SSF58104 73 314 3.53E-52 T 12-10-2018 AFR_13590 9680369bcbc9a79e813ff82f90eacffa 358 Gene3D G3DSA:3.40.50.720 3 149 4.7E-13 T 12-10-2018 AFR_13590 9680369bcbc9a79e813ff82f90eacffa 358 SUPERFAMILY SSF51735 3 90 2.9E-8 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19425 7e78fc10ab380b52a6de841154accd5c 132 Pfam PF12680 SnoaL-like domain 8 106 1.0E-8 T 12-10-2018 IPR037401 SnoaL-like domain AFR_19425 7e78fc10ab380b52a6de841154accd5c 132 Gene3D G3DSA:3.10.450.50 3 120 2.0E-11 T 12-10-2018 AFR_19425 7e78fc10ab380b52a6de841154accd5c 132 SUPERFAMILY SSF54427 5 109 1.45E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_37670 43e9b7b88cf63cfe63e037492d6224c6 208 Gene3D G3DSA:1.10.10.60 11 60 3.9E-21 T 12-10-2018 AFR_37670 43e9b7b88cf63cfe63e037492d6224c6 208 SUPERFAMILY SSF46689 11 78 2.92E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37670 43e9b7b88cf63cfe63e037492d6224c6 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 65 2.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37670 43e9b7b88cf63cfe63e037492d6224c6 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_37670 43e9b7b88cf63cfe63e037492d6224c6 208 Gene3D G3DSA:1.10.357.10 62 199 1.7E-27 T 12-10-2018 AFR_40230 f4dba872a5802ed37dc0061cffea7963 306 PIRSF PIRSF000196 1 306 2.4E-113 T 12-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 AFR_40230 f4dba872a5802ed37dc0061cffea7963 306 SUPERFAMILY SSF51730 35 301 2.39E-74 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like AFR_40230 f4dba872a5802ed37dc0061cffea7963 306 Pfam PF01619 Proline dehydrogenase 42 298 1.6E-33 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 AFR_40230 f4dba872a5802ed37dc0061cffea7963 306 Gene3D G3DSA:3.20.20.530 19 304 2.7E-93 T 12-10-2018 AFR_25885 b2a42e91b994621656b6084f0252ea7b 143 Pfam PF01638 HxlR-like helix-turn-helix 29 116 3.0E-19 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_25885 b2a42e91b994621656b6084f0252ea7b 143 SUPERFAMILY SSF46785 18 127 1.15E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_25885 b2a42e91b994621656b6084f0252ea7b 143 Gene3D G3DSA:1.10.10.10 3 129 5.3E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_10360 02500a5926886189a28bcee2002cf508 327 SUPERFAMILY SSF52129 14 237 2.65E-13 T 12-10-2018 IPR029030 Caspase-like domain superfamily AFR_10360 02500a5926886189a28bcee2002cf508 327 Pfam PF00656 Caspase domain 19 219 5.7E-15 T 12-10-2018 AFR_10360 02500a5926886189a28bcee2002cf508 327 Gene3D G3DSA:3.40.50.1460 16 266 2.6E-19 T 12-10-2018 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 Gene3D G3DSA:1.10.287.950 153 469 2.1E-64 T 12-10-2018 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 130 150 5.7E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 311 338 5.7E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 340 369 5.7E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 388 417 5.7E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 230 259 5.7E-22 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 Pfam PF00672 HAMP domain 153 201 6.4E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 SUPERFAMILY SSF58104 173 466 9.55E-63 T 12-10-2018 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 273 436 1.4E-31 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 SMART SM00304 153 205 1.4E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_03455 0b6930537b3b9ca0fd48e3c1cfa8a344 473 SMART SM00283 220 467 1.2E-48 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFR_25170 7b60505a2883daa15e621d3568199291 376 Pfam PF01139 tRNA-splicing ligase RtcB 21 79 1.4E-8 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFR_25170 7b60505a2883daa15e621d3568199291 376 Gene3D G3DSA:3.90.1860.10 97 355 9.1E-58 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFR_25170 7b60505a2883daa15e621d3568199291 376 Gene3D G3DSA:3.90.1860.10 3 92 7.3E-15 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFR_25170 7b60505a2883daa15e621d3568199291 376 Pfam PF01139 tRNA-splicing ligase RtcB 115 354 3.4E-46 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFR_25170 7b60505a2883daa15e621d3568199291 376 TIGRFAM TIGR03073 release_rtcB: release factor H-coupled RctB family protein 4 347 1.2E-94 T 12-10-2018 IPR017510 Release factor H-coupled RctB family protein AFR_25170 7b60505a2883daa15e621d3568199291 376 SUPERFAMILY SSF103365 8 354 7.06E-79 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFR_29095 80046a2ba237cdb47b41f5c5ae46ad14 271 SUPERFAMILY SSF51556 2 269 1.81E-47 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_29095 80046a2ba237cdb47b41f5c5ae46ad14 271 Gene3D G3DSA:3.20.20.140 1 271 6.5E-73 T 12-10-2018 AFR_29095 80046a2ba237cdb47b41f5c5ae46ad14 271 Pfam PF04909 Amidohydrolase 2 269 3.2E-36 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_29960 ad0c9c2ae467fcc5d9a97f1b89b2738c 111 Gene3D G3DSA:3.30.1050.10 6 111 2.9E-13 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_29960 ad0c9c2ae467fcc5d9a97f1b89b2738c 111 Pfam PF02036 SCP-2 sterol transfer family 20 111 8.0E-9 T 12-10-2018 IPR003033 SCP2 sterol-binding domain AFR_29960 ad0c9c2ae467fcc5d9a97f1b89b2738c 111 SUPERFAMILY SSF55718 11 111 7.77E-17 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_28640 e71f36a1a3e1310225804f2746fdc92e 168 Gene3D G3DSA:1.10.1660.10 4 57 5.5E-6 T 12-10-2018 AFR_28640 e71f36a1a3e1310225804f2746fdc92e 168 Pfam PF12728 Helix-turn-helix domain 9 55 4.7E-12 T 12-10-2018 AFR_28640 e71f36a1a3e1310225804f2746fdc92e 168 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 55 1.2E-13 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_28640 e71f36a1a3e1310225804f2746fdc92e 168 SUPERFAMILY SSF46955 9 57 6.59E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_09425 05c580e7b5dbf158ab1bd26745338949 282 Gene3D G3DSA:1.10.760.10 150 244 4.8E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFR_09425 05c580e7b5dbf158ab1bd26745338949 282 Gene3D G3DSA:1.10.760.10 62 143 6.7E-9 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFR_09425 05c580e7b5dbf158ab1bd26745338949 282 Pfam PF00034 Cytochrome c 64 109 6.0E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09425 05c580e7b5dbf158ab1bd26745338949 282 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 162 235 2.3E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_09425 05c580e7b5dbf158ab1bd26745338949 282 SUPERFAMILY SSF46626 157 236 3.49E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFR_09425 05c580e7b5dbf158ab1bd26745338949 282 PIRSF PIRSF000007 7 282 1.2E-97 T 12-10-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AFR_09425 05c580e7b5dbf158ab1bd26745338949 282 SUPERFAMILY SSF46626 34 145 1.02E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFR_37930 a910fdc74eabb37b0235a04449561276 1050 SUPERFAMILY SSF51206 478 566 2.78E-6 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFR_37930 a910fdc74eabb37b0235a04449561276 1050 Gene3D G3DSA:2.60.120.10 468 579 6.0E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_09095 ee9dd0999686d5f30becd6dfe9635b7b 697 Pfam PF13449 Esterase-like activity of phytase 431 680 9.4E-45 T 12-10-2018 IPR027372 Phytase-like domain AFR_09095 ee9dd0999686d5f30becd6dfe9635b7b 697 SUPERFAMILY SSF75011 349 679 1.02E-5 T 12-10-2018 AFR_09095 ee9dd0999686d5f30becd6dfe9635b7b 697 Gene3D G3DSA:2.130.10.10 25 247 1.4E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_09095 ee9dd0999686d5f30becd6dfe9635b7b 697 SUPERFAMILY SSF50969 114 401 5.1E-17 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFR_01740 9dfbf5e37882f0d7e493a8f38c44fc8f 171 Gene3D G3DSA:1.10.10.10 99 171 1.7E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01740 9dfbf5e37882f0d7e493a8f38c44fc8f 171 Pfam PF04545 Sigma-70, region 4 113 161 6.8E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFR_01740 9dfbf5e37882f0d7e493a8f38c44fc8f 171 Pfam PF04542 Sigma-70 region 2 15 80 1.0E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_01740 9dfbf5e37882f0d7e493a8f38c44fc8f 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 161 2.6E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_01740 9dfbf5e37882f0d7e493a8f38c44fc8f 171 SUPERFAMILY SSF88659 101 165 7.41E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_01740 9dfbf5e37882f0d7e493a8f38c44fc8f 171 SUPERFAMILY SSF88946 3 99 3.61E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_01740 9dfbf5e37882f0d7e493a8f38c44fc8f 171 Gene3D G3DSA:1.10.1740.10 1 77 5.2E-19 T 12-10-2018 AFR_34410 5fd0f2bc29ae70f28c770c5dbc4dac57 126 Gene3D G3DSA:1.10.1660.10 1 123 7.0E-30 T 12-10-2018 AFR_34410 5fd0f2bc29ae70f28c770c5dbc4dac57 126 SUPERFAMILY SSF46955 1 110 4.4E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_34410 5fd0f2bc29ae70f28c770c5dbc4dac57 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34410 5fd0f2bc29ae70f28c770c5dbc4dac57 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34410 5fd0f2bc29ae70f28c770c5dbc4dac57 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 6.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34410 5fd0f2bc29ae70f28c770c5dbc4dac57 126 SMART SM00422 1 69 1.3E-26 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_34410 5fd0f2bc29ae70f28c770c5dbc4dac57 126 Pfam PF13411 MerR HTH family regulatory protein 2 63 5.3E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_10950 018996321fe728baf57e693f04ce63e0 190 SUPERFAMILY SSF46689 1 75 9.48E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_10950 018996321fe728baf57e693f04ce63e0 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10950 018996321fe728baf57e693f04ce63e0 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10950 018996321fe728baf57e693f04ce63e0 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 55 9.5E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_10950 018996321fe728baf57e693f04ce63e0 190 Pfam PF14278 Transcriptional regulator C-terminal region 88 157 1.8E-9 T 12-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type AFR_10950 018996321fe728baf57e693f04ce63e0 190 Gene3D G3DSA:1.10.357.10 1 174 9.1E-38 T 12-10-2018 AFR_26410 f6b198d9046cfa8a4373b7e103746267 71 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 40 71 2.9E-22 T 12-10-2018 IPR008515 Ubiquitin-like, Pup AFR_26410 f6b198d9046cfa8a4373b7e103746267 71 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 71 17.43 T 12-10-2018 IPR008515 Ubiquitin-like, Pup AFR_26410 f6b198d9046cfa8a4373b7e103746267 71 Pfam PF05639 Pup-like protein 4 71 1.7E-29 T 12-10-2018 IPR008515 Ubiquitin-like, Pup AFR_39060 abcb577efa32a23ab1832d39dc9aba38 64 SUPERFAMILY SSF47789 9 62 3.14E-6 T 12-10-2018 AFR_39060 abcb577efa32a23ab1832d39dc9aba38 64 Gene3D G3DSA:1.10.150.20 4 63 2.1E-8 T 12-10-2018 AFR_19065 e73c21016cb1e61acfb043c194940db5 510 SMART SM00248 463 492 0.0095 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_19065 e73c21016cb1e61acfb043c194940db5 510 SMART SM00248 430 459 370.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_19065 e73c21016cb1e61acfb043c194940db5 510 SUPERFAMILY SSF48403 396 503 1.87E-17 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_19065 e73c21016cb1e61acfb043c194940db5 510 Pfam PF12796 Ankyrin repeats (3 copies) 414 494 8.5E-7 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFR_19065 e73c21016cb1e61acfb043c194940db5 510 Gene3D G3DSA:1.25.40.20 382 508 1.8E-20 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 Gene3D G3DSA:3.90.79.10 166 310 2.7E-21 T 12-10-2018 AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 Pfam PF00293 NUDIX domain 172 296 5.8E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 Pfam PF00293 NUDIX domain 9 132 1.8E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 SUPERFAMILY SSF55811 171 309 2.3E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 Gene3D G3DSA:3.90.79.10 5 143 4.5E-22 T 12-10-2018 AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 SUPERFAMILY SSF55811 7 138 1.35E-22 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 ProSitePatterns PS00893 Nudix box signature. 206 227 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_04990 35fab1f9e78b53589a9f83fedbdb95d6 315 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_32730 1699b10baa3dd95eedaae01a75ab692a 189 Pfam PF00486 Transcriptional regulatory protein, C terminal 107 178 4.2E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_32730 1699b10baa3dd95eedaae01a75ab692a 189 Gene3D G3DSA:1.10.10.10 89 187 1.9E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32730 1699b10baa3dd95eedaae01a75ab692a 189 SMART SM00862 107 178 1.9E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_32730 1699b10baa3dd95eedaae01a75ab692a 189 SUPERFAMILY SSF46894 91 179 5.1E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_29410 f2d8e088346b17e258003f3e3c8a3a0e 223 Gene3D G3DSA:3.40.50.300 1 221 4.4E-66 T 12-10-2018 AFR_29410 f2d8e088346b17e258003f3e3c8a3a0e 223 SUPERFAMILY SSF52540 4 219 1.17E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29410 f2d8e088346b17e258003f3e3c8a3a0e 223 SMART SM00382 29 216 8.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_29410 f2d8e088346b17e258003f3e3c8a3a0e 223 Pfam PF00005 ABC transporter 20 168 1.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_29410 f2d8e088346b17e258003f3e3c8a3a0e 223 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_23085 fc47dbb9674ae60841ff74913166815c 172 Pfam PF12697 Alpha/beta hydrolase family 3 166 2.8E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_23085 fc47dbb9674ae60841ff74913166815c 172 Gene3D G3DSA:3.40.50.1820 1 171 4.7E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_23085 fc47dbb9674ae60841ff74913166815c 172 SUPERFAMILY SSF53474 4 169 6.24E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_09920 173b3c3c7650e7b1abb517bfe59af9f3 811 SMART SM00460 470 540 1.4E-20 T 12-10-2018 IPR002931 Transglutaminase-like AFR_09920 173b3c3c7650e7b1abb517bfe59af9f3 811 Pfam PF13559 Domain of unknown function (DUF4129) 677 747 1.2E-5 T 12-10-2018 IPR025403 Domain of unknown function DUF4129 AFR_09920 173b3c3c7650e7b1abb517bfe59af9f3 811 Pfam PF01841 Transglutaminase-like superfamily 422 538 1.9E-27 T 12-10-2018 IPR002931 Transglutaminase-like AFR_09920 173b3c3c7650e7b1abb517bfe59af9f3 811 SUPERFAMILY SSF54001 412 547 5.89E-32 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_09920 173b3c3c7650e7b1abb517bfe59af9f3 811 Gene3D G3DSA:3.10.620.30 388 569 3.8E-25 T 12-10-2018 AFR_33215 634d718584f5e0e6858e0dbe85f1da80 1019 SUPERFAMILY SSF57850 115 155 6.18E-6 T 12-10-2018 AFR_33215 634d718584f5e0e6858e0dbe85f1da80 1019 Pfam PF14447 Prokaryotic RING finger family 4 116 161 5.7E-16 T 12-10-2018 AFR_20355 deb89a4601e455f053225557de62ca4f 124 SMART SM00418 5 87 1.0E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20355 deb89a4601e455f053225557de62ca4f 124 SUPERFAMILY SSF46785 3 104 2.35E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20355 deb89a4601e455f053225557de62ca4f 124 Gene3D G3DSA:1.10.10.10 4 112 5.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20355 deb89a4601e455f053225557de62ca4f 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 7.7E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20355 deb89a4601e455f053225557de62ca4f 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 7.7E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20355 deb89a4601e455f053225557de62ca4f 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 7.7E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_20355 deb89a4601e455f053225557de62ca4f 124 Pfam PF01022 Bacterial regulatory protein, arsR family 12 60 1.7E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_22080 ba7721c7117f3d77fe46c19188801e0f 307 SMART SM00530 10 83 2.6E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_22080 ba7721c7117f3d77fe46c19188801e0f 307 Gene3D G3DSA:3.30.450.180 111 287 4.1E-13 T 12-10-2018 AFR_22080 ba7721c7117f3d77fe46c19188801e0f 307 SUPERFAMILY SSF47413 31 80 1.03E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_22080 ba7721c7117f3d77fe46c19188801e0f 307 Gene3D G3DSA:1.10.260.40 23 103 5.2E-7 T 12-10-2018 AFR_22080 ba7721c7117f3d77fe46c19188801e0f 307 Pfam PF13560 Helix-turn-helix domain 18 86 5.7E-13 T 12-10-2018 AFR_32080 a0998808aebf2fa3b04b8a15cd974d90 119 SUPERFAMILY SSF54909 1 112 4.18E-25 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_32080 a0998808aebf2fa3b04b8a15cd974d90 119 Pfam PF03795 YCII-related domain 1 99 1.4E-13 T 12-10-2018 IPR005545 YCII-related AFR_32080 a0998808aebf2fa3b04b8a15cd974d90 119 Gene3D G3DSA:3.30.70.1060 1 115 2.1E-32 T 12-10-2018 AFR_38410 d3d5fc4ba5e8f1d292fc286d5a25c146 423 SUPERFAMILY SSF143456 258 419 1.09E-21 T 12-10-2018 AFR_38410 d3d5fc4ba5e8f1d292fc286d5a25c146 423 Pfam PF02622 Uncharacterized ACR, COG1678 272 419 9.4E-19 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 AFR_38410 d3d5fc4ba5e8f1d292fc286d5a25c146 423 Gene3D G3DSA:3.40.1740.10 249 423 1.4E-31 T 12-10-2018 AFR_38410 d3d5fc4ba5e8f1d292fc286d5a25c146 423 Pfam PF00656 Caspase domain 13 150 1.1E-7 T 12-10-2018 AFR_38410 d3d5fc4ba5e8f1d292fc286d5a25c146 423 Gene3D G3DSA:3.40.50.1460 11 245 1.3E-16 T 12-10-2018 AFR_38410 d3d5fc4ba5e8f1d292fc286d5a25c146 423 SUPERFAMILY SSF52129 11 201 2.41E-9 T 12-10-2018 IPR029030 Caspase-like domain superfamily AFR_37980 3a6b2ea387df6be47725866d7a145ca9 249 Pfam PF09818 Predicted ATPase of the ABC class 41 68 3.5E-4 T 12-10-2018 IPR019195 ABC transporter, ATPase, putative AFR_37980 3a6b2ea387df6be47725866d7a145ca9 249 SUPERFAMILY SSF52540 43 214 1.58E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37980 3a6b2ea387df6be47725866d7a145ca9 249 Gene3D G3DSA:3.40.50.300 42 227 2.5E-11 T 12-10-2018 AFR_37980 3a6b2ea387df6be47725866d7a145ca9 249 SMART SM00382 46 218 3.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 SUPERFAMILY SSF46894 151 218 2.89E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.6E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 SMART SM00421 155 212 2.1E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 Gene3D G3DSA:3.40.50.12740 3 218 3.1E-69 T 12-10-2018 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 SMART SM00448 3 118 4.8E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 6.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 SUPERFAMILY SSF52172 1 137 2.7E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_33665 2710c81f42e0bae5145bec0afe64ff21 227 Pfam PF00072 Response regulator receiver domain 5 118 4.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 Pfam PF16918 Protein kinase G tetratricopeptide repeat 435 732 9.5E-64 T 12-10-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 Gene3D G3DSA:1.25.40.10 435 729 7.1E-76 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 Gene3D G3DSA:1.10.510.10 230 398 6.5E-102 T 12-10-2018 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 Gene3D G3DSA:3.30.200.20 100 229 6.5E-102 T 12-10-2018 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 Pfam PF00069 Protein kinase domain 148 418 1.3E-29 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 SUPERFAMILY SSF48452 502 609 4.03E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 Gene3D G3DSA:1.25.40.10 437 575 7.1E-76 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 Pfam PF16919 Protein kinase G rubredoxin domain 41 147 5.0E-34 T 12-10-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 AFR_26235 c7e2c69313ca688dec5506d58cb872e0 734 SUPERFAMILY SSF56112 133 445 3.01E-45 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_06730 ce2a44e9a691d88887c2f677a2b553c6 275 SMART SM00382 37 221 7.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_06730 ce2a44e9a691d88887c2f677a2b553c6 275 Pfam PF00005 ABC transporter 28 174 1.3E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_06730 ce2a44e9a691d88887c2f677a2b553c6 275 SUPERFAMILY SSF52540 25 221 3.34E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06730 ce2a44e9a691d88887c2f677a2b553c6 275 Gene3D G3DSA:3.40.50.300 6 239 1.1E-51 T 12-10-2018 AFR_42620 959746e2fb2c7740b0da4e1c2639e855 631 Pfam PF09826 Beta propeller domain 105 622 7.2E-131 T 12-10-2018 IPR019198 Beta propeller domain-containing family AFR_25965 27fa9ed58a2ecde46cee8402bf5c7971 274 SUPERFAMILY SSF56317 8 268 1.44E-59 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_25965 27fa9ed58a2ecde46cee8402bf5c7971 274 Pfam PF00795 Carbon-nitrogen hydrolase 10 243 5.7E-36 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFR_25965 27fa9ed58a2ecde46cee8402bf5c7971 274 Gene3D G3DSA:3.60.110.10 1 272 1.5E-64 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_17360 e9e8985e8ad56ea1bb3b7f040857604f 308 Gene3D G3DSA:3.40.50.720 1 123 7.4E-30 T 12-10-2018 AFR_17360 e9e8985e8ad56ea1bb3b7f040857604f 308 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 116 6.0E-21 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_17360 e9e8985e8ad56ea1bb3b7f040857604f 308 Pfam PF08635 Putative oxidoreductase C terminal 119 185 3.6E-6 T 12-10-2018 IPR013944 Oxidoreductase putative, C-terminal AFR_17360 e9e8985e8ad56ea1bb3b7f040857604f 308 SUPERFAMILY SSF51735 1 129 1.98E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_17360 e9e8985e8ad56ea1bb3b7f040857604f 308 SUPERFAMILY SSF55347 136 265 4.09E-16 T 12-10-2018 AFR_17360 e9e8985e8ad56ea1bb3b7f040857604f 308 Gene3D G3DSA:3.30.360.10 124 308 1.3E-27 T 12-10-2018 AFR_37815 1e83c2799741ac0b46885b40b7756502 221 Pfam PF09335 SNARE associated Golgi protein 48 175 1.1E-21 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_37505 4f867f901336170b8194dda492d7aac2 221 Gene3D G3DSA:1.20.1260.10 56 220 4.3E-55 T 12-10-2018 IPR012347 Ferritin-like AFR_37505 4f867f901336170b8194dda492d7aac2 221 Pfam PF03713 Domain of unknown function (DUF305) 64 217 3.7E-44 T 12-10-2018 IPR005183 Domain of unknown function DUF305 AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 Gene3D G3DSA:3.50.50.60 8 338 2.8E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 4.0E-11 T 12-10-2018 AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.0E-11 T 12-10-2018 AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 4.0E-11 T 12-10-2018 AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 4.0E-11 T 12-10-2018 AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 Gene3D G3DSA:3.30.9.50 41 268 2.8E-66 T 12-10-2018 AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 Pfam PF01494 FAD binding domain 5 320 5.5E-19 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_05585 6690293c9c7f21304dbe87915feb12f6 388 SUPERFAMILY SSF51905 6 363 2.72E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_25085 c690932338f457da6924caa8acb858ff 92 SUPERFAMILY SSF47090 29 76 1.96E-7 T 12-10-2018 IPR036365 PGBD-like superfamily AFR_25085 c690932338f457da6924caa8acb858ff 92 Pfam PF01471 Putative peptidoglycan binding domain 44 71 4.5E-6 T 12-10-2018 IPR002477 Peptidoglycan binding-like AFR_25085 c690932338f457da6924caa8acb858ff 92 Gene3D G3DSA:1.10.101.10 26 76 1.2E-7 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFR_32515 fb296b86e7374e8db607c2672c025f46 324 Gene3D G3DSA:3.30.460.20 12 130 4.9E-25 T 12-10-2018 AFR_32515 fb296b86e7374e8db607c2672c025f46 324 Gene3D G3DSA:1.20.58.340 248 324 8.0E-14 T 12-10-2018 AFR_32515 fb296b86e7374e8db607c2672c025f46 324 SUPERFAMILY SSF144083 261 321 1.01E-10 T 12-10-2018 AFR_32515 fb296b86e7374e8db607c2672c025f46 324 Pfam PF01544 CorA-like Mg2+ transporter protein 30 320 3.2E-54 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFR_32515 fb296b86e7374e8db607c2672c025f46 324 SUPERFAMILY SSF143865 5 259 1.57E-52 T 12-10-2018 AFR_32515 fb296b86e7374e8db607c2672c025f46 324 Gene3D G3DSA:1.20.58.340 131 246 8.0E-26 T 12-10-2018 AFR_15230 78eceb0a0aa29c1f40ae778531d5a378 199 Gene3D G3DSA:3.40.50.150 14 176 1.3E-12 T 12-10-2018 AFR_15230 78eceb0a0aa29c1f40ae778531d5a378 199 SUPERFAMILY SSF53335 36 183 9.45E-19 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_15230 78eceb0a0aa29c1f40ae778531d5a378 199 Pfam PF13649 Methyltransferase domain 42 140 1.6E-7 T 12-10-2018 AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 SUPERFAMILY SSF55874 454 601 6.55E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 SMART SM00388 397 465 1.2E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 554 1.2E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 583 1.2E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 Gene3D G3DSA:3.30.565.10 475 605 2.0E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 SMART SM00086 321 363 0.0072 T 12-10-2018 IPR001610 PAC motif AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 Pfam PF13188 PAS domain 271 305 1.4E-5 T 12-10-2018 IPR000014 PAS domain AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 SMART SM00387 505 605 6.6E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 Gene3D G3DSA:1.10.287.130 388 467 3.0E-8 T 12-10-2018 AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 Gene3D G3DSA:3.30.450.20 255 312 6.0E-6 T 12-10-2018 AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 SUPERFAMILY SSF47384 383 465 2.35E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 506 602 1.9E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 324 370 2.2E-6 T 12-10-2018 IPR000014 PAS domain AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 SUPERFAMILY SSF55785 258 360 4.01E-14 T 12-10-2018 IPR035965 PAS domain superfamily AFR_40350 a99ca9c40ddc3187dff75f96b6c1d4e3 606 Gene3D G3DSA:3.30.450.20 318 387 3.5E-12 T 12-10-2018 AFR_23735 e143be1a218780adadb0fb0404b7fd2a 276 SUPERFAMILY SSF51735 3 270 6.67E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23735 e143be1a218780adadb0fb0404b7fd2a 276 Gene3D G3DSA:3.40.50.720 2 275 6.4E-38 T 12-10-2018 AFR_23735 e143be1a218780adadb0fb0404b7fd2a 276 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 151 1.7E-21 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_05065 20066fdef2d5041193809850f169ccd4 616 Gene3D G3DSA:3.90.780.10 415 614 4.8E-54 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_05065 20066fdef2d5041193809850f169ccd4 616 Pfam PF02872 5'-nucleotidase, C-terminal domain 413 576 3.3E-39 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_05065 20066fdef2d5041193809850f169ccd4 616 Gene3D G3DSA:3.60.21.10 55 409 7.8E-56 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_05065 20066fdef2d5041193809850f169ccd4 616 SUPERFAMILY SSF55816 411 614 2.22E-50 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_05065 20066fdef2d5041193809850f169ccd4 616 Pfam PF00149 Calcineurin-like phosphoesterase 67 316 3.6E-4 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_05065 20066fdef2d5041193809850f169ccd4 616 SUPERFAMILY SSF56300 63 411 9.81E-60 T 12-10-2018 AFR_05065 20066fdef2d5041193809850f169ccd4 616 PRINTS PR01607 Apyrase family signature 299 322 1.4E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_05065 20066fdef2d5041193809850f169ccd4 616 PRINTS PR01607 Apyrase family signature 552 571 1.4E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_05065 20066fdef2d5041193809850f169ccd4 616 PRINTS PR01607 Apyrase family signature 477 500 1.4E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_05065 20066fdef2d5041193809850f169ccd4 616 PRINTS PR01607 Apyrase family signature 60 78 1.4E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFR_21745 6bbff40100fa48e8556ef103e19257f0 342 SUPERFAMILY SSF56112 17 304 1.14E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_21745 6bbff40100fa48e8556ef103e19257f0 342 Gene3D G3DSA:3.90.1200.10 173 306 6.6E-7 T 12-10-2018 AFR_21745 6bbff40100fa48e8556ef103e19257f0 342 Pfam PF01636 Phosphotransferase enzyme family 31 267 1.4E-14 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_11180 c76c3e6951b02aad12dacb79fa58e7aa 323 SUPERFAMILY SSF53697 134 296 5.01E-37 T 12-10-2018 AFR_11180 c76c3e6951b02aad12dacb79fa58e7aa 323 Gene3D G3DSA:3.40.50.10490 129 315 9.7E-44 T 12-10-2018 AFR_11180 c76c3e6951b02aad12dacb79fa58e7aa 323 Pfam PF01380 SIS domain 161 289 2.6E-18 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_11180 c76c3e6951b02aad12dacb79fa58e7aa 323 Gene3D G3DSA:1.10.10.10 28 112 1.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11180 c76c3e6951b02aad12dacb79fa58e7aa 323 Pfam PF01418 Helix-turn-helix domain, rpiR family 34 104 1.7E-13 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AFR_11180 c76c3e6951b02aad12dacb79fa58e7aa 323 SUPERFAMILY SSF46689 34 104 1.7E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_33095 5696dcaa04400b6a78c44033d0b53d7d 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 5.4E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33095 5696dcaa04400b6a78c44033d0b53d7d 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 5.4E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33095 5696dcaa04400b6a78c44033d0b53d7d 124 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 5.4E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33095 5696dcaa04400b6a78c44033d0b53d7d 124 SMART SM00422 4 73 5.8E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_33095 5696dcaa04400b6a78c44033d0b53d7d 124 SUPERFAMILY SSF46955 4 118 1.21E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_33095 5696dcaa04400b6a78c44033d0b53d7d 124 Gene3D G3DSA:1.10.1660.10 3 122 1.2E-30 T 12-10-2018 AFR_33095 5696dcaa04400b6a78c44033d0b53d7d 124 Pfam PF13411 MerR HTH family regulatory protein 4 70 2.1E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_29240 8381de5562240eab69b0588dfad2fef3 251 Pfam PF12706 Beta-lactamase superfamily domain 32 213 3.1E-19 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_29240 8381de5562240eab69b0588dfad2fef3 251 SMART SM00849 18 213 3.4E-5 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_29240 8381de5562240eab69b0588dfad2fef3 251 SUPERFAMILY SSF56281 1 244 4.72E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_29240 8381de5562240eab69b0588dfad2fef3 251 Gene3D G3DSA:3.60.15.10 1 246 2.2E-59 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_12750 e988e1f66b296b74f8f3bd346f9fab13 188 SUPERFAMILY SSF48498 80 186 2.16E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12750 e988e1f66b296b74f8f3bd346f9fab13 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 59 3.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_12750 e988e1f66b296b74f8f3bd346f9fab13 188 Gene3D G3DSA:1.10.357.10 2 188 1.1E-36 T 12-10-2018 AFR_12750 e988e1f66b296b74f8f3bd346f9fab13 188 SUPERFAMILY SSF46689 7 76 1.15E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 SUPERFAMILY SSF53474 4 292 1.55E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 Gene3D G3DSA:3.40.50.1820 1 293 7.5E-74 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 Pfam PF00561 alpha/beta hydrolase fold 26 148 4.3E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 PRINTS PR00412 Epoxide hydrolase signature 269 291 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 PRINTS PR00412 Epoxide hydrolase signature 100 113 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 PRINTS PR00412 Epoxide hydrolase signature 32 50 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 PRINTS PR00412 Epoxide hydrolase signature 114 127 1.5E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_28975 e61aea49ac3bf8680f954800d2b50fac 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_17745 5b9be010659f3f26baa38b0328b4f183 147 Pfam PF00072 Response regulator receiver domain 8 128 8.5E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17745 5b9be010659f3f26baa38b0328b4f183 147 Gene3D G3DSA:3.40.50.2300 1 143 5.8E-30 T 12-10-2018 AFR_17745 5b9be010659f3f26baa38b0328b4f183 147 SMART SM00448 6 128 5.1E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17745 5b9be010659f3f26baa38b0328b4f183 147 SUPERFAMILY SSF52172 5 132 9.39E-29 T 12-10-2018 IPR011006 CheY-like superfamily AFR_42855 3fbc13affcfd18ede8b882a01fb0aeab 514 PIRSF PIRSF010361 13 474 5.9E-108 T 12-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane AFR_42855 3fbc13affcfd18ede8b882a01fb0aeab 514 Pfam PF09594 Glycosyltransferase family 87 152 365 7.3E-8 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 AFR_06610 7968934790786586c8adb6fa2020d36a 364 SUPERFAMILY SSF140453 198 263 6.41E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily AFR_16825 e00ab9769dd2e1df765b1978def06f91 285 Pfam PF01261 Xylose isomerase-like TIM barrel 31 217 4.7E-16 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_16825 e00ab9769dd2e1df765b1978def06f91 285 Gene3D G3DSA:3.20.20.150 3 283 3.0E-40 T 12-10-2018 AFR_16825 e00ab9769dd2e1df765b1978def06f91 285 SUPERFAMILY SSF51658 22 270 1.19E-31 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_16025 4dcbcfa5a6eae6944c4eba1f6ff5f942 209 SUPERFAMILY SSF51182 2 196 4.27E-68 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_16025 4dcbcfa5a6eae6944c4eba1f6ff5f942 209 Gene3D G3DSA:2.60.120.10 1 203 1.8E-67 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_16025 4dcbcfa5a6eae6944c4eba1f6ff5f942 209 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 7.8E-58 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFR_16025 4dcbcfa5a6eae6944c4eba1f6ff5f942 209 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 181 3.0E-67 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFR_20265 cbd7bd56c57339fe84d64c64fad08581 235 Gene3D G3DSA:3.40.50.300 3 234 3.0E-68 T 12-10-2018 AFR_20265 cbd7bd56c57339fe84d64c64fad08581 235 PIRSF PIRSF021497 1 234 1.9E-62 T 12-10-2018 IPR015124 Trehalose 2-sulfotransferase GO:0016740 MetaCyc: PWY-7746 AFR_20265 cbd7bd56c57339fe84d64c64fad08581 235 SUPERFAMILY SSF52540 4 231 4.93E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20265 cbd7bd56c57339fe84d64c64fad08581 235 Pfam PF09037 Stf0 sulphotransferase 4 231 4.2E-62 T 12-10-2018 IPR024628 Sulphotransferase Stf0, domain MetaCyc: PWY-7746 AFR_26945 36563719d31c4e73670f89fc6cd009e0 173 SUPERFAMILY SSF55961 9 169 1.26E-34 T 12-10-2018 AFR_26945 36563719d31c4e73670f89fc6cd009e0 173 Gene3D G3DSA:3.30.530.20 4 173 1.3E-37 T 12-10-2018 IPR023393 START-like domain superfamily AFR_26945 36563719d31c4e73670f89fc6cd009e0 173 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 31 142 2.4E-15 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_24875 35414626faa9c23886e974f1182579cb 494 SUPERFAMILY SSF51735 157 442 3.89E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24875 35414626faa9c23886e974f1182579cb 494 Gene3D G3DSA:3.40.50.720 141 279 9.7E-18 T 12-10-2018 AFR_24875 35414626faa9c23886e974f1182579cb 494 Gene3D G3DSA:3.40.50.720 284 466 4.2E-12 T 12-10-2018 AFR_24875 35414626faa9c23886e974f1182579cb 494 Pfam PF00106 short chain dehydrogenase 163 250 1.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 SUPERFAMILY SSF51690 116 281 3.02E-56 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 PIRSF PIRSF006250 6 284 8.8E-86 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 26 114 3.2E-25 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 Gene3D G3DSA:3.20.20.70 126 272 3.5E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 116 280 3.3E-55 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 Gene3D G3DSA:3.90.1170.20 11 279 3.5E-98 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 14 280 1.9E-90 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 AFR_41375 ba7a881b0a7a87773fa8b2023eebb124 286 SUPERFAMILY SSF54675 10 115 4.12E-28 T 12-10-2018 AFR_09250 81e96da991f219722afc8cf8dea194dd 305 Gene3D G3DSA:3.40.50.720 1 286 1.4E-68 T 12-10-2018 AFR_09250 81e96da991f219722afc8cf8dea194dd 305 SUPERFAMILY SSF51735 1 298 1.13E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_09250 81e96da991f219722afc8cf8dea194dd 305 Pfam PF08338 Domain of unknown function (DUF1731) 250 295 8.8E-16 T 12-10-2018 IPR013549 Domain of unknown function DUF1731 AFR_09250 81e96da991f219722afc8cf8dea194dd 305 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 8.6E-92 T 12-10-2018 IPR010099 Epimerase family protein SDR39U1 AFR_09250 81e96da991f219722afc8cf8dea194dd 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 130 2.8E-10 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_09860 5302845d226a9795a552b363a88c084c 306 Pfam PF00892 EamA-like transporter family 148 284 3.1E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_09860 5302845d226a9795a552b363a88c084c 306 Pfam PF00892 EamA-like transporter family 1 135 1.4E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_09860 5302845d226a9795a552b363a88c084c 306 SUPERFAMILY SSF103481 203 285 1.01E-8 T 12-10-2018 AFR_09860 5302845d226a9795a552b363a88c084c 306 SUPERFAMILY SSF103481 60 136 2.09E-11 T 12-10-2018 AFR_04755 fb8fb36a9ee01fa69f5d35cc2767ae26 383 Gene3D G3DSA:3.40.50.2300 48 367 1.5E-49 T 12-10-2018 AFR_04755 fb8fb36a9ee01fa69f5d35cc2767ae26 383 SUPERFAMILY SSF53822 43 381 3.34E-45 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_04755 fb8fb36a9ee01fa69f5d35cc2767ae26 383 Pfam PF13458 Periplasmic binding protein 46 369 1.7E-34 T 12-10-2018 IPR028081 Leucine-binding protein domain AFR_04755 fb8fb36a9ee01fa69f5d35cc2767ae26 383 Gene3D G3DSA:3.40.50.2300 150 377 1.5E-49 T 12-10-2018 AFR_42710 511a460ccd8e9518f569c04ecc44615f 170 Pfam PF07681 DoxX 1 89 1.9E-10 T 12-10-2018 IPR032808 DoxX family AFR_29500 59b775d90fd0864c241b7f142498dda7 541 Gene3D G3DSA:1.20.1250.20 10 396 2.6E-37 T 12-10-2018 AFR_29500 59b775d90fd0864c241b7f142498dda7 541 Pfam PF05977 Transmembrane secretion effector 6 515 5.0E-121 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_29500 59b775d90fd0864c241b7f142498dda7 541 SUPERFAMILY SSF103473 12 401 4.58E-45 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_22625 dfaa8a1492504cbd3abfd7b5751ad4ed 253 PIRSF PIRSF006648 2 253 2.5E-65 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_22625 dfaa8a1492504cbd3abfd7b5751ad4ed 253 Pfam PF01061 ABC-2 type transporter 11 217 1.4E-22 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_35335 ed6c10dda27dd754d41ba791f4963d6e 573 Gene3D G3DSA:3.40.50.300 8 177 1.3E-19 T 12-10-2018 AFR_35335 ed6c10dda27dd754d41ba791f4963d6e 573 Gene3D G3DSA:3.40.50.300 194 381 4.0E-12 T 12-10-2018 AFR_35335 ed6c10dda27dd754d41ba791f4963d6e 573 SMART SM00487 10 187 2.4E-14 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFR_35335 ed6c10dda27dd754d41ba791f4963d6e 573 SMART SM00382 29 191 1.7E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_35335 ed6c10dda27dd754d41ba791f4963d6e 573 SUPERFAMILY SSF52540 28 375 7.17E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_35335 ed6c10dda27dd754d41ba791f4963d6e 573 Pfam PF04851 Type III restriction enzyme, res subunit 14 166 7.3E-11 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFR_38895 0487751f87222b7d2f849000f38a4d74 335 SUPERFAMILY SSF56112 9 304 1.02E-57 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_38895 0487751f87222b7d2f849000f38a4d74 335 Gene3D G3DSA:3.90.1200.10 102 329 1.7E-67 T 12-10-2018 AFR_38895 0487751f87222b7d2f849000f38a4d74 335 Pfam PF01636 Phosphotransferase enzyme family 24 239 1.8E-49 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_38895 0487751f87222b7d2f849000f38a4d74 335 Gene3D G3DSA:3.30.200.20 7 101 2.0E-29 T 12-10-2018 AFR_36520 29b00245c0ce81944b95e920930f2751 392 Pfam PF04188 Mannosyltransferase (PIG-V) 62 182 5.4E-5 T 12-10-2018 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 Reactome: R-HSA-162710 AFR_06305 7f16fee6df2e7726183a8bc335cb5b31 436 SUPERFAMILY SSF103473 17 383 7.85E-36 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_06305 7f16fee6df2e7726183a8bc335cb5b31 436 Pfam PF07690 Major Facilitator Superfamily 22 263 2.3E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_06305 7f16fee6df2e7726183a8bc335cb5b31 436 Gene3D G3DSA:1.20.1250.20 15 383 1.5E-32 T 12-10-2018 AFR_28855 de7e724f909ef648f91512f0e844602e 131 Gene3D G3DSA:3.10.450.50 8 131 2.1E-31 T 12-10-2018 AFR_28855 de7e724f909ef648f91512f0e844602e 131 Pfam PF12680 SnoaL-like domain 22 111 1.1E-12 T 12-10-2018 IPR037401 SnoaL-like domain AFR_28855 de7e724f909ef648f91512f0e844602e 131 SUPERFAMILY SSF54427 13 117 6.73E-21 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_17920 b5193f35e75efde024199b4b76e97626 130 Gene3D G3DSA:1.10.10.10 5 127 9.4E-40 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_17920 b5193f35e75efde024199b4b76e97626 130 SUPERFAMILY SSF46785 23 122 4.83E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17920 b5193f35e75efde024199b4b76e97626 130 Pfam PF01638 HxlR-like helix-turn-helix 30 115 9.1E-29 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_28900 b26904fb77dae4a0c77e6a260e9ba0fd 252 SMART SM00422 3 72 1.3E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_28900 b26904fb77dae4a0c77e6a260e9ba0fd 252 SUPERFAMILY SSF46955 4 100 8.79E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_28900 b26904fb77dae4a0c77e6a260e9ba0fd 252 Pfam PF13411 MerR HTH family regulatory protein 4 65 4.9E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_28900 b26904fb77dae4a0c77e6a260e9ba0fd 252 Gene3D G3DSA:1.10.1660.10 6 251 1.4E-23 T 12-10-2018 AFR_09680 8dfa048b76cc8a47658b4c6c3f3c1c17 296 SUPERFAMILY SSF51679 11 289 3.39E-41 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_09680 8dfa048b76cc8a47658b4c6c3f3c1c17 296 Gene3D G3DSA:3.20.20.30 8 289 3.8E-45 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_09680 8dfa048b76cc8a47658b4c6c3f3c1c17 296 Pfam PF00296 Luciferase-like monooxygenase 12 218 6.2E-35 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_12460 e4a90f106350ec81456a6a9bb75e74c1 483 SUPERFAMILY SSF52540 39 262 2.6E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12460 e4a90f106350ec81456a6a9bb75e74c1 483 Pfam PF01926 50S ribosome-binding GTPase 44 74 7.0E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFR_12460 e4a90f106350ec81456a6a9bb75e74c1 483 Gene3D G3DSA:3.40.50.300 5 228 5.5E-11 T 12-10-2018 AFR_02210 7f33cc840cd7619bb6a457f0aed12de7 431 Pfam PF05977 Transmembrane secretion effector 20 414 3.1E-38 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_02210 7f33cc840cd7619bb6a457f0aed12de7 431 SUPERFAMILY SSF103473 26 417 1.57E-42 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_02210 7f33cc840cd7619bb6a457f0aed12de7 431 Gene3D G3DSA:1.20.1250.20 26 417 1.5E-33 T 12-10-2018 AFR_20295 2d8aea4894c25f43ff72da98b3e68af0 166 Gene3D G3DSA:1.10.10.10 3 126 3.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20295 2d8aea4894c25f43ff72da98b3e68af0 166 Pfam PF01638 HxlR-like helix-turn-helix 19 108 9.6E-14 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_20295 2d8aea4894c25f43ff72da98b3e68af0 166 SUPERFAMILY SSF46785 7 118 6.45E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_03895 1c0eb8d683cf665320d6f5a30a113663 363 Pfam PF06224 Winged helix DNA-binding domain 51 351 3.4E-32 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 AFR_39730 4f9e61734c1e9ccad932963164a3a4ff 315 SUPERFAMILY SSF53474 41 282 3.95E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_39730 4f9e61734c1e9ccad932963164a3a4ff 315 Gene3D G3DSA:3.40.50.1820 33 300 3.8E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_39730 4f9e61734c1e9ccad932963164a3a4ff 315 Pfam PF10503 Esterase PHB depolymerase 56 183 5.9E-11 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AFR_40310 0c96473113028bfc3ed80a85ea9318b0 164 Pfam PF10722 Putative bacterial sensory transduction regulator 7 127 4.2E-24 T 12-10-2018 IPR019660 Putative sensory transduction regulator YbjN AFR_40310 0c96473113028bfc3ed80a85ea9318b0 164 SUPERFAMILY SSF69635 4 130 1.41E-32 T 12-10-2018 AFR_40310 0c96473113028bfc3ed80a85ea9318b0 164 Gene3D G3DSA:3.30.1460.10 2 139 1.6E-10 T 12-10-2018 AFR_19435 f9d4780e351fa94b43e1202d95b68b52 389 Gene3D G3DSA:1.20.1250.20 3 195 3.9E-26 T 12-10-2018 AFR_19435 f9d4780e351fa94b43e1202d95b68b52 389 Pfam PF07690 Major Facilitator Superfamily 8 340 2.1E-37 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_19435 f9d4780e351fa94b43e1202d95b68b52 389 Gene3D G3DSA:1.20.1250.20 196 381 2.3E-15 T 12-10-2018 AFR_19435 f9d4780e351fa94b43e1202d95b68b52 389 SUPERFAMILY SSF103473 4 375 9.55E-53 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_31645 2b1156112cee6d09e717621911643d71 201 Pfam PF12787 EcsC protein family 40 198 1.9E-11 T 12-10-2018 IPR024787 EcsC protein AFR_27735 b2c9224eef1d7c5bf95bbc5d7ca387ec 637 Pfam PF00128 Alpha amylase, catalytic domain 161 487 4.7E-66 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27735 b2c9224eef1d7c5bf95bbc5d7ca387ec 637 Pfam PF14078 Domain of unknown function (DUF4259) 3 117 1.9E-9 T 12-10-2018 IPR025355 Protein of unknown function DUF4259 AFR_27735 b2c9224eef1d7c5bf95bbc5d7ca387ec 637 Gene3D G3DSA:3.90.400.10 238 302 4.3E-133 T 12-10-2018 AFR_27735 b2c9224eef1d7c5bf95bbc5d7ca387ec 637 SUPERFAMILY SSF51445 138 573 1.64E-114 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_27735 b2c9224eef1d7c5bf95bbc5d7ca387ec 637 SMART SM00642 146 511 5.8E-109 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_27735 b2c9224eef1d7c5bf95bbc5d7ca387ec 637 Gene3D G3DSA:3.20.20.80 138 569 4.3E-133 T 12-10-2018 AFR_11735 a4a28fd02cb6e0b76de1bc71879215a8 129 Pfam PF12158 Protein of unknown function (DUF3592) 3 125 2.7E-14 T 12-10-2018 IPR021994 Protein of unknown function DUF3592 AFR_29635 bd07af093b1d834dbfda5eaab92fb617 444 SUPERFAMILY SSF46785 346 419 2.9E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_29635 bd07af093b1d834dbfda5eaab92fb617 444 Gene3D G3DSA:1.10.10.10 345 439 4.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29635 bd07af093b1d834dbfda5eaab92fb617 444 Gene3D G3DSA:1.10.10.10 254 344 1.7E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29635 bd07af093b1d834dbfda5eaab92fb617 444 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 267 437 1.9E-35 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFR_29635 bd07af093b1d834dbfda5eaab92fb617 444 Pfam PF04079 Segregation and condensation complex subunit ScpB 270 428 3.1E-53 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFR_29635 bd07af093b1d834dbfda5eaab92fb617 444 SUPERFAMILY SSF46785 265 341 8.98E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_34915 bc8322193e5e1e139a594616f9d4f785 822 SUPERFAMILY SSF52540 3 816 2.9E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34915 bc8322193e5e1e139a594616f9d4f785 822 Pfam PF13558 Putative exonuclease SbcCD, C subunit 713 779 2.4E-12 T 12-10-2018 AFR_34915 bc8322193e5e1e139a594616f9d4f785 822 Gene3D G3DSA:3.40.50.300 601 820 5.1E-21 T 12-10-2018 AFR_34915 bc8322193e5e1e139a594616f9d4f785 822 Gene3D G3DSA:3.40.50.300 1 305 1.1E-33 T 12-10-2018 AFR_34915 bc8322193e5e1e139a594616f9d4f785 822 Pfam PF13476 AAA domain 3 207 1.4E-16 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 Gene3D G3DSA:3.40.50.2300 6 139 4.1E-37 T 12-10-2018 AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 Pfam PF00072 Response regulator receiver domain 22 131 4.6E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 SMART SM00448 20 131 1.5E-40 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 Pfam PF00486 Transcriptional regulatory protein, C terminal 171 243 9.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 Gene3D G3DSA:1.10.10.10 147 250 2.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 SUPERFAMILY SSF52172 15 143 2.85E-41 T 12-10-2018 IPR011006 CheY-like superfamily AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 SMART SM00862 169 243 8.9E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFR_20565 55b8a324782bf1d4217a04a55645dd46 251 SUPERFAMILY SSF46894 147 244 9.64E-29 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_21265 c7a87f67e01b1f895fbea5f1874bb217 289 SUPERFAMILY SSF52540 1 208 1.33E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_21265 c7a87f67e01b1f895fbea5f1874bb217 289 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_21265 c7a87f67e01b1f895fbea5f1874bb217 289 Gene3D G3DSA:3.40.50.300 1 219 5.0E-58 T 12-10-2018 AFR_21265 c7a87f67e01b1f895fbea5f1874bb217 289 SMART SM00382 20 197 2.7E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_21265 c7a87f67e01b1f895fbea5f1874bb217 289 Pfam PF00005 ABC transporter 12 148 3.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_08240 197a2d5fbe5c1a1fc60e78cd4e09256f 422 Gene3D G3DSA:3.50.50.60 2 279 5.7E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_08240 197a2d5fbe5c1a1fc60e78cd4e09256f 422 Pfam PF01593 Flavin containing amine oxidoreductase 16 410 6.8E-32 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFR_08240 197a2d5fbe5c1a1fc60e78cd4e09256f 422 SUPERFAMILY SSF51905 7 413 8.63E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_23795 33c8e62c61fff062c3ad0595cfdf145e 212 SUPERFAMILY SSF52540 16 206 3.98E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_23795 33c8e62c61fff062c3ad0595cfdf145e 212 Gene3D G3DSA:3.40.50.300 45 210 1.4E-43 T 12-10-2018 AFR_23795 33c8e62c61fff062c3ad0595cfdf145e 212 Gene3D G3DSA:3.40.50.300 2 44 1.0E-5 T 12-10-2018 AFR_23795 33c8e62c61fff062c3ad0595cfdf145e 212 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 21 165 2.9E-6 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 AFR_06235 60fe22a35ff61681eb846862098565ea 157 SUPERFAMILY SSF46785 4 146 4.44E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_06235 60fe22a35ff61681eb846862098565ea 157 Gene3D G3DSA:1.10.10.10 6 151 1.2E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_06235 60fe22a35ff61681eb846862098565ea 157 SMART SM00347 32 135 1.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_06235 60fe22a35ff61681eb846862098565ea 157 Pfam PF12802 MarR family 38 97 5.8E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_19500 f67ec051130baddfa6442db974d4f95b 267 Gene3D G3DSA:3.40.50.620 9 164 8.3E-22 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_19500 f67ec051130baddfa6442db974d4f95b 267 Pfam PF00733 Asparagine synthase 12 72 2.3E-6 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFR_19500 f67ec051130baddfa6442db974d4f95b 267 SUPERFAMILY SSF52402 9 232 3.31E-28 T 12-10-2018 AFR_19500 f67ec051130baddfa6442db974d4f95b 267 PIRSF PIRSF006661 3 266 5.4E-82 T 12-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AFR_19500 f67ec051130baddfa6442db974d4f95b 267 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 257 3.0E-50 T 12-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AFR_14445 9167623561e750b7f5507d4dc38b196b 276 SUPERFAMILY SSF103481 38 135 1.7E-8 T 12-10-2018 AFR_14445 9167623561e750b7f5507d4dc38b196b 276 SUPERFAMILY SSF103481 179 275 3.4E-9 T 12-10-2018 AFR_14445 9167623561e750b7f5507d4dc38b196b 276 Pfam PF00892 EamA-like transporter family 2 131 1.6E-6 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_14445 9167623561e750b7f5507d4dc38b196b 276 Pfam PF00892 EamA-like transporter family 147 274 1.5E-6 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_42510 79cc0027151f6ef96875ecff302d0cd1 393 Gene3D G3DSA:1.10.260.150 80 380 1.1E-59 T 12-10-2018 AFR_42510 79cc0027151f6ef96875ecff302d0cd1 393 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 115 295 2.3E-36 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_42510 79cc0027151f6ef96875ecff302d0cd1 393 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 116 295 1.5E-26 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_01520 2434d2a9e9d10c19c48f64ca722e402c 329 Pfam PF01032 FecCD transport family 1 325 1.7E-89 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_01520 2434d2a9e9d10c19c48f64ca722e402c 329 SUPERFAMILY SSF81345 2 325 1.7E-75 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_01520 2434d2a9e9d10c19c48f64ca722e402c 329 Gene3D G3DSA:1.10.3470.10 1 329 3.1E-94 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_17625 386c51b64dad7c032110a1efbf51997d 689 SUPERFAMILY SSF48208 220 658 1.36E-53 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_17625 386c51b64dad7c032110a1efbf51997d 689 Gene3D G3DSA:1.50.10.10 232 600 4.3E-47 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_17625 386c51b64dad7c032110a1efbf51997d 689 Gene3D G3DSA:2.70.98.50 2 157 5.2E-17 T 12-10-2018 AFR_17625 386c51b64dad7c032110a1efbf51997d 689 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 4 147 2.0E-12 T 12-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 AFR_35105 8bf165a88b7ae304e5a28c98e7778d08 135 Pfam PF13577 SnoaL-like domain 3 125 6.7E-20 T 12-10-2018 IPR037401 SnoaL-like domain AFR_35105 8bf165a88b7ae304e5a28c98e7778d08 135 SUPERFAMILY SSF54427 3 130 1.08E-25 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_35105 8bf165a88b7ae304e5a28c98e7778d08 135 Gene3D G3DSA:3.10.450.50 1 133 9.5E-28 T 12-10-2018 AFR_11065 6679a62ff55081fd93f50e226d6f1f78 236 SUPERFAMILY SSF53474 3 234 1.5E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11065 6679a62ff55081fd93f50e226d6f1f78 236 Pfam PF12697 Alpha/beta hydrolase family 3 228 6.5E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_11065 6679a62ff55081fd93f50e226d6f1f78 236 Gene3D G3DSA:3.40.50.1820 1 235 4.4E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12675 9f58045ed17d014ee44ef59dba37c2a9 112 SUPERFAMILY SSF52091 9 100 7.26E-10 T 12-10-2018 IPR036513 STAS domain superfamily AFR_12675 9f58045ed17d014ee44ef59dba37c2a9 112 Gene3D G3DSA:3.30.750.24 8 111 1.1E-9 T 12-10-2018 IPR036513 STAS domain superfamily AFR_12675 9f58045ed17d014ee44ef59dba37c2a9 112 Pfam PF01740 STAS domain 11 100 3.6E-6 T 12-10-2018 IPR002645 STAS domain AFR_35670 8b356612f39e063ae2d68e221b00fe47 220 SMART SM00987 45 213 8.9E-33 T 12-10-2018 AFR_35670 8b356612f39e063ae2d68e221b00fe47 220 SUPERFAMILY SSF52141 20 217 3.6E-48 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_35670 8b356612f39e063ae2d68e221b00fe47 220 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 15 214 2.6E-71 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 AFR_35670 8b356612f39e063ae2d68e221b00fe47 220 Gene3D G3DSA:3.40.470.10 19 220 2.7E-54 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_35670 8b356612f39e063ae2d68e221b00fe47 220 SMART SM00986 45 213 8.9E-33 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_35670 8b356612f39e063ae2d68e221b00fe47 220 Pfam PF03167 Uracil DNA glycosylase superfamily 45 212 9.5E-36 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFR_16820 a60bbe2b42e5e7b051b17dc030dbdf51 416 Gene3D G3DSA:3.90.226.30 258 416 4.4E-64 T 12-10-2018 AFR_16820 a60bbe2b42e5e7b051b17dc030dbdf51 416 Pfam PF09861 Domain of unknown function (DUF2088) 31 190 1.5E-18 T 12-10-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 AFR_16820 a60bbe2b42e5e7b051b17dc030dbdf51 416 Gene3D G3DSA:3.40.50.11440 6 257 1.2E-63 T 12-10-2018 AFR_10475 d262daa7fda501128415079a4dc38835 306 Gene3D G3DSA:3.40.630.30 8 306 1.7E-51 T 12-10-2018 AFR_10475 d262daa7fda501128415079a4dc38835 306 SUPERFAMILY SSF55729 27 302 1.0E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_10475 d262daa7fda501128415079a4dc38835 306 Pfam PF00583 Acetyltransferase (GNAT) family 221 293 2.3E-10 T 12-10-2018 IPR000182 GNAT domain AFR_31130 5c1047d8ae1db244a32a8f922022f33d 209 SUPERFAMILY SSF48498 82 183 1.11E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_31130 5c1047d8ae1db244a32a8f922022f33d 209 SUPERFAMILY SSF46689 4 71 2.46E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_31130 5c1047d8ae1db244a32a8f922022f33d 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 4.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_31130 5c1047d8ae1db244a32a8f922022f33d 209 Gene3D G3DSA:1.10.357.10 3 186 3.3E-24 T 12-10-2018 AFR_23030 7632421e1cfe96ece9b1b5cafb473472 490 Gene3D G3DSA:1.20.1250.20 254 458 5.1E-17 T 12-10-2018 AFR_23030 7632421e1cfe96ece9b1b5cafb473472 490 Gene3D G3DSA:1.20.1720.10 12 223 1.2E-44 T 12-10-2018 AFR_23030 7632421e1cfe96ece9b1b5cafb473472 490 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_23030 7632421e1cfe96ece9b1b5cafb473472 490 SUPERFAMILY SSF103473 7 456 1.2E-57 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_23030 7632421e1cfe96ece9b1b5cafb473472 490 Pfam PF07690 Major Facilitator Superfamily 17 407 9.9E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_22255 54ec3c341458a5b0c72e3d025e435eef 229 Gene3D G3DSA:3.40.50.300 1 216 1.8E-56 T 12-10-2018 AFR_22255 54ec3c341458a5b0c72e3d025e435eef 229 ProSitePatterns PS00211 ABC transporters family signature. 117 131 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_22255 54ec3c341458a5b0c72e3d025e435eef 229 SMART SM00382 27 194 3.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_22255 54ec3c341458a5b0c72e3d025e435eef 229 SUPERFAMILY SSF52540 3 207 1.7E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_22255 54ec3c341458a5b0c72e3d025e435eef 229 Pfam PF00005 ABC transporter 19 144 1.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_14315 a6829bafe50ebd28881d553a73678cbe 311 Gene3D G3DSA:3.50.30.50 56 311 1.8E-24 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_14315 a6829bafe50ebd28881d553a73678cbe 311 SUPERFAMILY SSF102198 78 310 1.44E-22 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_14315 a6829bafe50ebd28881d553a73678cbe 311 Pfam PF04199 Putative cyclase 84 240 1.2E-22 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 Gene3D G3DSA:3.40.50.720 15 305 7.6E-74 T 12-10-2018 AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 SUPERFAMILY SSF51735 22 261 2.05E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 217 4.4E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 4.4E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 4.4E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 198 4.4E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 4.4E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_29000 04ccf7362ac3b665749a1a042f9b704b 307 Pfam PF00106 short chain dehydrogenase 25 219 2.0E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15590 f61bea346c9efaf83350ceff0fe82689 484 Gene3D G3DSA:2.115.10.20 22 316 2.1E-87 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_15590 f61bea346c9efaf83350ceff0fe82689 484 Gene3D G3DSA:2.60.120.560 317 480 8.9E-34 T 12-10-2018 AFR_15590 f61bea346c9efaf83350ceff0fe82689 484 Pfam PF04616 Glycosyl hydrolases family 43 27 309 1.6E-58 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_15590 f61bea346c9efaf83350ceff0fe82689 484 SUPERFAMILY SSF75005 25 309 4.97E-74 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_32850 9ca34cea3ea59211f514ab0a0b643ad7 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.9E-9 T 12-10-2018 AFR_32850 9ca34cea3ea59211f514ab0a0b643ad7 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 2.9E-9 T 12-10-2018 AFR_32850 9ca34cea3ea59211f514ab0a0b643ad7 441 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 36 2.8E-7 T 12-10-2018 AFR_32850 9ca34cea3ea59211f514ab0a0b643ad7 441 Gene3D G3DSA:3.50.50.60 1 382 3.4E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_32850 9ca34cea3ea59211f514ab0a0b643ad7 441 SUPERFAMILY SSF51905 1 366 7.59E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_18950 ebc0bea5bc41e8d005f39c916a33b840 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 313 5.5E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_27520 8636c6583153ac2e528b422bc27f864b 242 Pfam PF00149 Calcineurin-like phosphoesterase 2 192 1.1E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_27520 8636c6583153ac2e528b422bc27f864b 242 Gene3D G3DSA:3.60.21.40 1 98 2.2E-55 T 12-10-2018 AFR_27520 8636c6583153ac2e528b422bc27f864b 242 SUPERFAMILY SSF56300 2 235 1.03E-45 T 12-10-2018 AFR_27520 8636c6583153ac2e528b422bc27f864b 242 Gene3D G3DSA:3.30.750.180 99 213 2.2E-55 T 12-10-2018 AFR_27520 8636c6583153ac2e528b422bc27f864b 242 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 236 30.584 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 AFR_21605 1b782b4e1379083f294b2bbd8f654b5c 390 PIRSF PIRSF036794 5 390 5.7E-83 T 12-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type AFR_21605 1b782b4e1379083f294b2bbd8f654b5c 390 Gene3D G3DSA:1.20.1440.30 128 268 1.2E-34 T 12-10-2018 AFR_21605 1b782b4e1379083f294b2bbd8f654b5c 390 Pfam PF05139 Erythromycin esterase 43 384 1.2E-62 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 AFR_21605 1b782b4e1379083f294b2bbd8f654b5c 390 Gene3D G3DSA:3.40.1660.10 17 309 1.2E-34 T 12-10-2018 AFR_21605 1b782b4e1379083f294b2bbd8f654b5c 390 Gene3D G3DSA:3.30.1870.10 45 127 1.2E-34 T 12-10-2018 AFR_21605 1b782b4e1379083f294b2bbd8f654b5c 390 SUPERFAMILY SSF159501 9 386 1.31E-80 T 12-10-2018 AFR_08635 5d4e335033682f6387b7a899e759fd76 304 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 293 2.3E-83 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_08635 5d4e335033682f6387b7a899e759fd76 304 SUPERFAMILY SSF161111 17 215 3.4E-51 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_08635 5d4e335033682f6387b7a899e759fd76 304 SUPERFAMILY SSF160240 218 293 1.57E-10 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFR_08635 5d4e335033682f6387b7a899e759fd76 304 Gene3D G3DSA:1.20.1510.10 19 214 5.8E-38 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFR_08635 5d4e335033682f6387b7a899e759fd76 304 Pfam PF01545 Cation efflux family 24 214 6.2E-42 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFR_17020 c9e23a52d8656b754a4d1c2e49737b76 326 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 14 319 3.8E-68 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 AFR_18940 8f825283b442ba72860aea6ab23a81e9 328 Pfam PF13407 Periplasmic binding protein domain 43 301 1.3E-50 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_18940 8f825283b442ba72860aea6ab23a81e9 328 Gene3D G3DSA:3.40.50.2300 143 283 2.7E-99 T 12-10-2018 AFR_18940 8f825283b442ba72860aea6ab23a81e9 328 Gene3D G3DSA:3.40.50.2300 42 300 2.7E-99 T 12-10-2018 AFR_18940 8f825283b442ba72860aea6ab23a81e9 328 SUPERFAMILY SSF53822 37 321 2.36E-72 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_14470 43fda40a01782452c44031e7829bda11 320 Gene3D G3DSA:1.10.1740.10 3 94 2.6E-27 T 12-10-2018 AFR_14470 43fda40a01782452c44031e7829bda11 320 SUPERFAMILY SSF88659 123 181 2.62E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_14470 43fda40a01782452c44031e7829bda11 320 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 181 2.0E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_14470 43fda40a01782452c44031e7829bda11 320 Pfam PF08281 Sigma-70, region 4 126 175 1.2E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_14470 43fda40a01782452c44031e7829bda11 320 SUPERFAMILY SSF88946 9 88 1.06E-25 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14470 43fda40a01782452c44031e7829bda11 320 SUPERFAMILY SSF54427 197 305 1.17E-11 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_14470 43fda40a01782452c44031e7829bda11 320 Pfam PF04542 Sigma-70 region 2 16 82 1.0E-21 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14470 43fda40a01782452c44031e7829bda11 320 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 8 308 3.2E-105 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria AFR_14470 43fda40a01782452c44031e7829bda11 320 Gene3D G3DSA:3.10.450.50 192 317 1.6E-12 T 12-10-2018 AFR_14470 43fda40a01782452c44031e7829bda11 320 Gene3D G3DSA:1.10.10.10 124 182 1.3E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07130 c84dceb3ccff028d52016d975d848f46 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 69 8.2E-17 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_07130 c84dceb3ccff028d52016d975d848f46 100 Gene3D G3DSA:3.30.70.100 1 99 5.0E-36 T 12-10-2018 AFR_07130 c84dceb3ccff028d52016d975d848f46 100 SUPERFAMILY SSF54909 1 97 6.13E-23 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_20760 cf29da3153494c70c285b2df28c9b1a0 334 Gene3D G3DSA:3.20.20.150 1 328 2.2E-67 T 12-10-2018 AFR_20760 cf29da3153494c70c285b2df28c9b1a0 334 Pfam PF01261 Xylose isomerase-like TIM barrel 20 236 1.2E-26 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_20760 cf29da3153494c70c285b2df28c9b1a0 334 SUPERFAMILY SSF51658 1 332 1.38E-46 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_17865 f69e283021402011658093099a69a341 486 Pfam PF04616 Glycosyl hydrolases family 43 25 320 2.2E-48 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 AFR_17865 f69e283021402011658093099a69a341 486 SUPERFAMILY SSF75005 24 321 3.14E-49 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_17865 f69e283021402011658093099a69a341 486 Gene3D G3DSA:2.115.10.20 16 328 2.5E-75 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_17865 f69e283021402011658093099a69a341 486 Gene3D G3DSA:2.80.10.50 438 485 7.1E-12 T 12-10-2018 AFR_17865 f69e283021402011658093099a69a341 486 Gene3D G3DSA:2.80.10.50 345 387 1.0E-7 T 12-10-2018 AFR_17865 f69e283021402011658093099a69a341 486 Gene3D G3DSA:2.80.10.50 388 437 2.7E-14 T 12-10-2018 AFR_17865 f69e283021402011658093099a69a341 486 SUPERFAMILY SSF50370 346 486 1.76E-39 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_17865 f69e283021402011658093099a69a341 486 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 348 426 1.4E-19 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_17865 f69e283021402011658093099a69a341 486 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 432 485 3.8E-12 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_41635 1c3a6fe3b63dd092ba2ccec3fa31ce0c 267 Pfam PF00753 Metallo-beta-lactamase superfamily 25 187 8.0E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_41635 1c3a6fe3b63dd092ba2ccec3fa31ce0c 267 SMART SM00849 28 187 4.4E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_41635 1c3a6fe3b63dd092ba2ccec3fa31ce0c 267 SUPERFAMILY SSF56281 5 258 2.3E-45 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_41635 1c3a6fe3b63dd092ba2ccec3fa31ce0c 267 Gene3D G3DSA:3.60.15.10 3 192 5.1E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_39970 313ea45b33a9100cf4def82cc52c8916 255 Pfam PF03703 Bacterial PH domain 154 228 1.0E-11 T 12-10-2018 IPR005182 Domain of unknown function DUF304 AFR_15765 d4dd95e3416ded7c49415c557143e028 393 Pfam PF07690 Major Facilitator Superfamily 12 350 8.9E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_15765 d4dd95e3416ded7c49415c557143e028 393 Gene3D G3DSA:1.20.1720.10 6 382 2.0E-88 T 12-10-2018 AFR_15765 d4dd95e3416ded7c49415c557143e028 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 77 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_15765 d4dd95e3416ded7c49415c557143e028 393 SUPERFAMILY SSF103473 6 387 2.09E-56 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_15765 d4dd95e3416ded7c49415c557143e028 393 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 379 1.1E-67 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 AFR_08535 144e737159ac1fb7274e827c60fd1ec0 318 Gene3D G3DSA:3.40.50.300 2 199 6.3E-49 T 12-10-2018 AFR_08535 144e737159ac1fb7274e827c60fd1ec0 318 SMART SM00382 37 178 2.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08535 144e737159ac1fb7274e827c60fd1ec0 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 4.6E-64 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_08535 144e737159ac1fb7274e827c60fd1ec0 318 PIRSF PIRSF002849 1 318 4.1E-129 T 12-10-2018 AFR_08535 144e737159ac1fb7274e827c60fd1ec0 318 SUPERFAMILY SSF52540 8 291 6.62E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08535 144e737159ac1fb7274e827c60fd1ec0 318 Gene3D G3DSA:1.10.8.300 206 314 1.9E-33 T 12-10-2018 AFR_29405 30fedc45712690f2f31791c0f0d454f2 389 Pfam PF12704 MacB-like periplasmic core domain 22 230 9.8E-12 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_29405 30fedc45712690f2f31791c0f0d454f2 389 Pfam PF02687 FtsX-like permease family 295 382 4.1E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_11535 fc5d1b3130c40e4bfe1de0ef86459ef8 423 Pfam PF02687 FtsX-like permease family 324 415 8.3E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_09320 956665e3331b6fb1974d040918d1e51e 317 SUPERFAMILY SSF52540 15 245 1.07E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09320 956665e3331b6fb1974d040918d1e51e 317 Gene3D G3DSA:3.40.50.300 10 252 2.0E-55 T 12-10-2018 AFR_09320 956665e3331b6fb1974d040918d1e51e 317 SMART SM00382 41 226 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_09320 956665e3331b6fb1974d040918d1e51e 317 Pfam PF00005 ABC transporter 33 176 8.0E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 Gene3D G3DSA:3.50.50.60 6 341 1.5E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.3E-48 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 4.3E-48 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 4.3E-48 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 4.3E-48 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 329 4.3E-48 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 4.3E-48 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 Pfam PF01494 FAD binding domain 5 341 1.6E-86 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 SUPERFAMILY SSF52833 383 495 1.04E-5 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 Gene3D G3DSA:3.30.70.2450 185 267 1.5E-109 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 Gene3D G3DSA:3.40.30.120 361 497 7.3E-18 T 12-10-2018 AFR_12830 c601733f6bf01a66ae3965e0082c47af 497 SUPERFAMILY SSF51905 6 348 2.0E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_08805 e399705793620d83b283fe072320956f 211 SUPERFAMILY SSF53335 4 184 1.84E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_08805 e399705793620d83b283fe072320956f 211 Pfam PF08241 Methyltransferase domain 20 106 5.5E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_08805 e399705793620d83b283fe072320956f 211 Gene3D G3DSA:3.40.50.150 2 198 2.2E-29 T 12-10-2018 AFR_39270 4407d8b4d3c66bd5d2660daa919ffb64 256 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 201 218 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 AFR_39270 4407d8b4d3c66bd5d2660daa919ffb64 256 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 256 35.048 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFR_39270 4407d8b4d3c66bd5d2660daa919ffb64 256 Gene3D G3DSA:3.40.1180.10 9 256 3.0E-80 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFR_39270 4407d8b4d3c66bd5d2660daa919ffb64 256 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 255 2.0E-59 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFR_39270 4407d8b4d3c66bd5d2660daa919ffb64 256 Pfam PF01255 Putative undecaprenyl diphosphate synthase 32 255 9.4E-69 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFR_39270 4407d8b4d3c66bd5d2660daa919ffb64 256 SUPERFAMILY SSF64005 22 251 1.57E-68 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 SUPERFAMILY SSF81333 12 73 3.4E-14 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 Pfam PF00137 ATP synthase subunit C 12 72 2.6E-11 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 Gene3D G3DSA:1.20.20.10 8 75 5.6E-18 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 74 12.989 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 PRINTS PR00124 ATP synthase C subunit signature 11 30 4.1E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 PRINTS PR00124 ATP synthase C subunit signature 49 74 4.1E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 PRINTS PR00124 ATP synthase C subunit signature 32 47 4.1E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37360 db620fddd0def2bf8d634b04d77ea306 75 ProSitePatterns PS00605 ATP synthase c subunit signature. 39 60 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_38660 6085f16c5dc63dd4bb4a9d873b23f787 465 Pfam PF01943 Polysaccharide biosynthesis protein 15 277 1.7E-13 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFR_30110 aa2b1ab80192437e25e959a9fe9bf201 488 SMART SM00813 282 481 6.7E-73 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_30110 aa2b1ab80192437e25e959a9fe9bf201 488 SUPERFAMILY SSF51011 362 487 1.87E-34 T 12-10-2018 AFR_30110 aa2b1ab80192437e25e959a9fe9bf201 488 SUPERFAMILY SSF51445 12 372 5.0E-107 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_30110 aa2b1ab80192437e25e959a9fe9bf201 488 Gene3D G3DSA:2.60.40.1180 1 486 1.2E-213 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_30110 aa2b1ab80192437e25e959a9fe9bf201 488 Gene3D G3DSA:3.20.20.80 13 372 1.2E-213 T 12-10-2018 AFR_30110 aa2b1ab80192437e25e959a9fe9bf201 488 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 282 481 7.7E-42 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 AFR_08070 ea4a50dc497ce71f31f9164fcf16b73c 135 Gene3D G3DSA:3.30.1490.190 83 135 2.5E-25 T 12-10-2018 AFR_08070 ea4a50dc497ce71f31f9164fcf16b73c 135 Gene3D G3DSA:1.10.10.10 1 82 1.3E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08070 ea4a50dc497ce71f31f9164fcf16b73c 135 Pfam PF01475 Ferric uptake regulator family 8 123 2.6E-29 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFR_08070 ea4a50dc497ce71f31f9164fcf16b73c 135 SUPERFAMILY SSF46785 8 129 1.14E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_37015 c05bcc21fd2b5d0b41090634f94d1da6 359 Gene3D G3DSA:3.40.50.620 1 137 3.1E-46 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_37015 c05bcc21fd2b5d0b41090634f94d1da6 359 Gene3D G3DSA:2.40.30.10 206 289 9.0E-10 T 12-10-2018 AFR_37015 c05bcc21fd2b5d0b41090634f94d1da6 359 SUPERFAMILY SSF52402 11 171 3.91E-26 T 12-10-2018 AFR_37015 c05bcc21fd2b5d0b41090634f94d1da6 359 Pfam PF03054 tRNA methyl transferase 1 283 1.9E-87 T 12-10-2018 AFR_37015 c05bcc21fd2b5d0b41090634f94d1da6 359 Gene3D G3DSA:2.30.30.280 140 205 6.2E-15 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 SUPERFAMILY SSF55729 18 161 1.21E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 Gene3D G3DSA:3.90.650.10 299 403 2.7E-7 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 TIGRFAM TIGR04050 MSMEG_0567_Cter: AIR synthase-related protein, MSMEG_0567 C-terminal family 162 447 2.2E-140 T 12-10-2018 IPR023911 Uncharacterised protein family, AIR synthase-related AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 SUPERFAMILY SSF56042 296 400 7.33E-10 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 Gene3D G3DSA:3.40.630.30 15 156 1.9E-23 T 12-10-2018 AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 Pfam PF02769 AIR synthase related protein, C-terminal domain 338 384 4.6E-6 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 SUPERFAMILY SSF55326 185 291 2.09E-19 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 Gene3D G3DSA:3.30.1330.10 161 292 1.0E-21 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 Pfam PF00586 AIR synthase related protein, N-terminal domain 197 288 2.3E-16 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 Pfam PF13673 Acetyltransferase (GNAT) domain 85 156 4.4E-6 T 12-10-2018 IPR000182 GNAT domain AFR_25970 a7afb087a7fcca6a7552bb78a8ca5932 450 TIGRFAM TIGR04045 MSMEG_0567_GNAT: putative N-acetyltransferase, MSMEG_0567 N-terminal domain family 16 155 9.2E-30 T 12-10-2018 IPR024035 GNAT N-acetyltransferase, putative AFR_18650 b479876fa3dba67d267afde876f84b5a 292 Gene3D G3DSA:3.40.830.10 27 288 1.0E-64 T 12-10-2018 AFR_18650 b479876fa3dba67d267afde876f84b5a 292 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 57 272 1.6E-33 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFR_18650 b479876fa3dba67d267afde876f84b5a 292 SUPERFAMILY SSF53213 38 287 1.31E-70 T 12-10-2018 AFR_18650 b479876fa3dba67d267afde876f84b5a 292 PIRSF PIRSF006157 35 291 9.7E-68 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 AFR_11405 b8ad3e7de5092057ef99766d51fbf6c6 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 272 6.1E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_11405 b8ad3e7de5092057ef99766d51fbf6c6 279 SUPERFAMILY SSF161098 11 279 3.64E-73 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11405 b8ad3e7de5092057ef99766d51fbf6c6 279 Gene3D G3DSA:1.10.3720.10 11 270 2.5E-66 T 12-10-2018 IPR035906 MetI-like superfamily AFR_34745 3fed17c5861e49cf6a88749b48099649 95 Pfam PF08922 Domain of unknown function (DUF1905) 5 91 3.9E-28 T 12-10-2018 IPR015018 Protein of unknown function DUF1905 AFR_34745 3fed17c5861e49cf6a88749b48099649 95 Gene3D G3DSA:2.40.30.100 33 93 3.1E-6 T 12-10-2018 IPR037079 AF2212/PG0164-like superfamily AFR_34745 3fed17c5861e49cf6a88749b48099649 95 SUPERFAMILY SSF141694 2 91 1.75E-18 T 12-10-2018 AFR_08590 f460ab756a0ae69dafefee34175fffc4 284 Gene3D G3DSA:3.30.200.20 1 93 8.5E-23 T 12-10-2018 AFR_08590 f460ab756a0ae69dafefee34175fffc4 284 SUPERFAMILY SSF56112 5 270 7.65E-51 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_08590 f460ab756a0ae69dafefee34175fffc4 284 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 132 144 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AFR_08590 f460ab756a0ae69dafefee34175fffc4 284 Pfam PF00069 Protein kinase domain 10 264 3.8E-32 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFR_08590 f460ab756a0ae69dafefee34175fffc4 284 Gene3D G3DSA:1.10.510.10 96 280 1.1E-30 T 12-10-2018 AFR_18630 8932ad13d7560062f971764f0805b505 145 Gene3D G3DSA:2.60.40.790 2 133 2.9E-29 T 12-10-2018 IPR008978 HSP20-like chaperone AFR_18630 8932ad13d7560062f971764f0805b505 145 Pfam PF00011 Hsp20/alpha crystallin family 36 132 1.5E-19 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFR_18630 8932ad13d7560062f971764f0805b505 145 SUPERFAMILY SSF49764 19 132 1.67E-29 T 12-10-2018 IPR008978 HSP20-like chaperone AFR_34585 148ba66c0156768bc19b5deaee28ce0d 332 Gene3D G3DSA:3.40.190.10 125 332 5.9E-32 T 12-10-2018 AFR_34585 148ba66c0156768bc19b5deaee28ce0d 332 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 327 3.4E-66 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 AFR_34585 148ba66c0156768bc19b5deaee28ce0d 332 Pfam PF13379 NMT1-like family 29 258 2.3E-25 T 12-10-2018 AFR_34585 148ba66c0156768bc19b5deaee28ce0d 332 Gene3D G3DSA:3.40.190.10 28 124 1.8E-12 T 12-10-2018 AFR_34585 148ba66c0156768bc19b5deaee28ce0d 332 SUPERFAMILY SSF53850 32 253 2.37E-43 T 12-10-2018 AFR_00415 f8b398151fd6fa801fb0afd72ae2b7b6 182 Gene3D G3DSA:3.40.50.2020 2 173 4.2E-25 T 12-10-2018 AFR_00415 f8b398151fd6fa801fb0afd72ae2b7b6 182 SUPERFAMILY SSF53271 23 164 2.84E-20 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_12500 6b24f172b6121a605119ee5276931eba 379 Gene3D G3DSA:1.10.3290.10 15 282 2.6E-45 T 12-10-2018 IPR036597 Fido-like domain superfamily AFR_12500 6b24f172b6121a605119ee5276931eba 379 Pfam PF02661 Fic/DOC family 111 209 2.3E-17 T 12-10-2018 IPR003812 Fido domain AFR_12500 6b24f172b6121a605119ee5276931eba 379 SUPERFAMILY SSF140931 85 276 9.68E-28 T 12-10-2018 IPR036597 Fido-like domain superfamily AFR_22260 d880a898cdc44b2227a7e915c457288c 318 Gene3D G3DSA:3.40.190.10 32 305 6.3E-67 T 12-10-2018 AFR_22260 d880a898cdc44b2227a7e915c457288c 318 SUPERFAMILY SSF53850 45 258 3.14E-33 T 12-10-2018 AFR_22260 d880a898cdc44b2227a7e915c457288c 318 Pfam PF09084 NMT1/THI5 like 69 247 3.6E-13 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_22260 d880a898cdc44b2227a7e915c457288c 318 SMART SM00062 29 261 0.0048 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_22260 d880a898cdc44b2227a7e915c457288c 318 Gene3D G3DSA:3.40.190.10 105 205 6.3E-67 T 12-10-2018 AFR_11200 fdcc5ae57e49634dd74e19474c596f20 477 Gene3D G3DSA:3.40.190.10 98 425 9.0E-53 T 12-10-2018 AFR_11200 fdcc5ae57e49634dd74e19474c596f20 477 SUPERFAMILY SSF53850 64 472 8.15E-47 T 12-10-2018 AFR_11200 fdcc5ae57e49634dd74e19474c596f20 477 Gene3D G3DSA:3.40.190.10 188 448 9.0E-53 T 12-10-2018 AFR_11200 fdcc5ae57e49634dd74e19474c596f20 477 Pfam PF01547 Bacterial extracellular solute-binding protein 83 382 4.9E-22 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_11200 fdcc5ae57e49634dd74e19474c596f20 477 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 27 475 3.5E-182 T 12-10-2018 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein AFR_42570 211f9e0912b7ee37105e8f31dc84ddf4 244 SUPERFAMILY SSF51219 24 219 2.88E-45 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily AFR_42570 211f9e0912b7ee37105e8f31dc84ddf4 244 Gene3D G3DSA:3.60.160.10 18 226 3.9E-26 T 12-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily AFR_42570 211f9e0912b7ee37105e8f31dc84ddf4 244 Pfam PF01987 Mitochondrial biogenesis AIM24 24 216 2.4E-32 T 12-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 AFR_29020 91f4b37fb402f84bd0ed3e6ca0404159 302 Pfam PF03631 Virulence factor BrkB 37 281 6.0E-30 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_10865 2b6da32db055843547cc90028d081548 157 Pfam PF07883 Cupin domain 60 120 1.2E-14 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_10865 2b6da32db055843547cc90028d081548 157 SUPERFAMILY SSF51182 34 146 1.45E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_10865 2b6da32db055843547cc90028d081548 157 Gene3D G3DSA:2.60.120.10 6 152 7.1E-30 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_02685 7acccd0ccfa7e9c21d79c4dc3b941ee1 374 PIRSF PIRSF000390 1 374 2.8E-100 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_02685 7acccd0ccfa7e9c21d79c4dc3b941ee1 374 SUPERFAMILY SSF53383 2 373 4.3E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_02685 7acccd0ccfa7e9c21d79c4dc3b941ee1 374 Gene3D G3DSA:3.90.1150.10 251 374 3.0E-32 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_02685 7acccd0ccfa7e9c21d79c4dc3b941ee1 374 Gene3D G3DSA:3.40.640.10 1 250 2.9E-84 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_02685 7acccd0ccfa7e9c21d79c4dc3b941ee1 374 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 10 369 2.3E-107 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFR_27645 64e74dbf48363552483b6f3c7429a10c 724 SUPERFAMILY SSF82866 458 690 7.85E-29 T 12-10-2018 AFR_27645 64e74dbf48363552483b6f3c7429a10c 724 SUPERFAMILY SSF82866 112 331 2.75E-30 T 12-10-2018 AFR_27645 64e74dbf48363552483b6f3c7429a10c 724 Gene3D G3DSA:1.20.1640.10 165 335 2.9E-6 T 12-10-2018 AFR_27645 64e74dbf48363552483b6f3c7429a10c 724 Pfam PF03176 MMPL family 45 360 2.4E-61 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_27645 64e74dbf48363552483b6f3c7429a10c 724 Pfam PF03176 MMPL family 429 691 8.1E-37 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_03305 b93446d3a773cda84b7d8f16ad7b3bcb 285 Gene3D G3DSA:3.40.50.720 4 263 1.4E-46 T 12-10-2018 AFR_03305 b93446d3a773cda84b7d8f16ad7b3bcb 285 Pfam PF13460 NAD(P)H-binding 9 116 3.7E-13 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_03305 b93446d3a773cda84b7d8f16ad7b3bcb 285 SUPERFAMILY SSF51735 2 236 1.79E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_03305 b93446d3a773cda84b7d8f16ad7b3bcb 285 Gene3D G3DSA:3.90.25.10 140 262 1.4E-46 T 12-10-2018 AFR_39900 5f61adb3fff8c77b1fefeb96a5143127 292 SUPERFAMILY SSF53448 2 278 1.67E-61 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_39900 5f61adb3fff8c77b1fefeb96a5143127 292 Pfam PF00483 Nucleotidyl transferase 2 266 2.8E-25 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFR_39900 5f61adb3fff8c77b1fefeb96a5143127 292 Gene3D G3DSA:3.90.550.10 1 289 6.8E-82 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_14565 4b402d74c5b5613c44828e48892f45af 271 SUPERFAMILY SSF53474 28 267 2.0E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14565 4b402d74c5b5613c44828e48892f45af 271 Gene3D G3DSA:3.40.50.1820 27 271 7.4E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14565 4b402d74c5b5613c44828e48892f45af 271 Pfam PF12697 Alpha/beta hydrolase family 35 262 6.3E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_04895 fa120c9bfe8162ea5690e055f0997439 271 Pfam PF00005 ABC transporter 22 173 1.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_04895 fa120c9bfe8162ea5690e055f0997439 271 Gene3D G3DSA:3.40.50.300 2 243 4.9E-56 T 12-10-2018 AFR_04895 fa120c9bfe8162ea5690e055f0997439 271 SUPERFAMILY SSF52540 5 233 2.77E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04895 fa120c9bfe8162ea5690e055f0997439 271 SMART SM00382 31 221 8.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_42755 74122a404c7775d781f37ab56e620df0 224 Gene3D G3DSA:1.20.120.450 2 160 1.3E-11 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_42755 74122a404c7775d781f37ab56e620df0 224 SUPERFAMILY SSF109854 3 161 5.49E-11 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_42755 74122a404c7775d781f37ab56e620df0 224 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 10 157 2.5E-12 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 Hamap MF_00008 Thymidylate synthase [thyA]. 3 265 39.135 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 Pfam PF00303 Thymidylate synthase 5 265 1.1E-119 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 ProSitePatterns PS00091 Thymidylate synthase active site. 128 156 - T 12-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 Gene3D G3DSA:3.30.572.10 3 265 1.6E-124 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 PRINTS PR00108 Thymidylate synthase family signature 161 187 1.9E-46 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 PRINTS PR00108 Thymidylate synthase family signature 199 216 1.9E-46 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 PRINTS PR00108 Thymidylate synthase family signature 44 65 1.9E-46 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 PRINTS PR00108 Thymidylate synthase family signature 143 158 1.9E-46 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 PRINTS PR00108 Thymidylate synthase family signature 117 136 1.9E-46 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 5 87 4.5E-36 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 86 265 4.8E-87 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_35135 502deb70b7e0bb5fb59c525815e3c0d7 265 SUPERFAMILY SSF55831 3 265 9.42E-120 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 SUPERFAMILY SSF51569 4 295 9.65E-72 T 12-10-2018 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 SUPERFAMILY SSF110921 402 517 3.4E-25 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 Pfam PF00682 HMGL-like 4 255 9.8E-41 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 4 525 2.4E-184 T 12-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 Gene3D G3DSA:3.20.20.70 3 328 2.5E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 SMART SM00917 377 521 9.7E-43 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 Gene3D G3DSA:3.30.160.270 397 519 2.2E-10 T 12-10-2018 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 Pfam PF08502 LeuA allosteric (dimerisation) domain 377 519 6.6E-29 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_36835 570db5354f3242d12baec58e9bec0ccd 528 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 10 26 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFR_00550 b4cee730e56b4f0241ef1aad90bec28f 165 SUPERFAMILY SSF116726 87 159 9.42E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_00550 b4cee730e56b4f0241ef1aad90bec28f 165 Pfam PF02080 TrkA-C domain 91 159 4.5E-14 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFR_00550 b4cee730e56b4f0241ef1aad90bec28f 165 PIRSF PIRSF005028 1 163 6.1E-62 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT AFR_00550 b4cee730e56b4f0241ef1aad90bec28f 165 Gene3D G3DSA:3.30.70.1450 89 163 4.3E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_02415 6b7183a572bb7c1070cddc429fa60d28 234 Pfam PF13490 Putative zinc-finger 7 39 2.3E-8 T 12-10-2018 IPR027383 Putative zinc-finger AFR_02415 6b7183a572bb7c1070cddc429fa60d28 234 Gene3D G3DSA:1.10.10.1320 5 67 1.0E-12 T 12-10-2018 AFR_02260 874c9856c79ebea45c58a7b29d8b06c4 165 SUPERFAMILY SSF55874 59 142 3.41E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_02260 874c9856c79ebea45c58a7b29d8b06c4 165 Gene3D G3DSA:3.30.565.10 27 155 2.5E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_02260 874c9856c79ebea45c58a7b29d8b06c4 165 Pfam PF13581 Histidine kinase-like ATPase domain 36 144 1.8E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_01380 bc7bfb603f75091a2be3aafc6564a9cc 527 SUPERFAMILY SSF51445 4 459 1.4E-119 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_01380 bc7bfb603f75091a2be3aafc6564a9cc 527 Gene3D G3DSA:3.90.400.10 105 174 1.8E-144 T 12-10-2018 AFR_01380 bc7bfb603f75091a2be3aafc6564a9cc 527 Gene3D G3DSA:3.20.20.80 5 458 1.8E-144 T 12-10-2018 AFR_01380 bc7bfb603f75091a2be3aafc6564a9cc 527 Pfam PF00128 Alpha amylase, catalytic domain 28 377 2.5E-77 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_01380 bc7bfb603f75091a2be3aafc6564a9cc 527 SMART SM00642 13 399 4.9E-119 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_23935 c91a6fe8a7ca9a429860c903bb81e3f4 340 SUPERFAMILY SSF103481 43 140 8.37E-6 T 12-10-2018 AFR_23935 c91a6fe8a7ca9a429860c903bb81e3f4 340 Pfam PF00892 EamA-like transporter family 3 138 3.4E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_05160 5d5a5879c9e324349e14c152b2131ec1 300 Gene3D G3DSA:3.40.50.300 1 298 3.1E-18 T 12-10-2018 AFR_05160 5d5a5879c9e324349e14c152b2131ec1 300 Pfam PF00685 Sulfotransferase domain 104 226 1.3E-5 T 12-10-2018 IPR000863 Sulfotransferase domain GO:0008146 AFR_05160 5d5a5879c9e324349e14c152b2131ec1 300 SUPERFAMILY SSF52540 2 291 2.32E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 39 55 1.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 61 77 1.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 273 291 1.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 102 112 1.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 353 368 1.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 Gene3D G3DSA:3.40.50.2300 41 369 2.5E-78 T 12-10-2018 AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 Gene3D G3DSA:3.40.50.2300 158 291 2.5E-78 T 12-10-2018 AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 SUPERFAMILY SSF53822 38 401 9.08E-76 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_18310 6fff31db94e5591f8ddba5bece075d2e 407 Pfam PF13458 Periplasmic binding protein 38 385 3.1E-61 T 12-10-2018 IPR028081 Leucine-binding protein domain AFR_11315 1f7ab12bf34745f9a06d8b0a31fd8182 184 SUPERFAMILY SSF51735 1 167 1.55E-17 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11315 1f7ab12bf34745f9a06d8b0a31fd8182 184 Gene3D G3DSA:3.40.50.720 1 161 5.3E-24 T 12-10-2018 AFR_06410 9a3ed320c56dc95d11137f8ebfae48e0 382 Pfam PF01979 Amidohydrolase family 56 360 1.7E-21 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_06410 9a3ed320c56dc95d11137f8ebfae48e0 382 TIGRFAM TIGR01224 hutI: imidazolonepropionase 23 379 4.6E-118 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06410 9a3ed320c56dc95d11137f8ebfae48e0 382 SUPERFAMILY SSF51556 58 341 5.96E-76 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_06410 9a3ed320c56dc95d11137f8ebfae48e0 382 Gene3D G3DSA:2.30.40.10 16 379 2.3E-139 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_06410 9a3ed320c56dc95d11137f8ebfae48e0 382 SUPERFAMILY SSF51338 3 381 1.03E-15 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_06410 9a3ed320c56dc95d11137f8ebfae48e0 382 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 382 44.747 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFR_06410 9a3ed320c56dc95d11137f8ebfae48e0 382 Gene3D G3DSA:3.20.20.140 59 342 2.3E-139 T 12-10-2018 AFR_42240 4abd2352f03f9065443957410b03b7a9 381 SUPERFAMILY SSF88659 82 139 4.3E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_42240 4abd2352f03f9065443957410b03b7a9 381 Pfam PF08281 Sigma-70, region 4 87 136 1.8E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_42240 4abd2352f03f9065443957410b03b7a9 381 Pfam PF04542 Sigma-70 region 2 2 58 5.0E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_42240 4abd2352f03f9065443957410b03b7a9 381 Gene3D G3DSA:1.10.1740.10 1 55 2.4E-8 T 12-10-2018 AFR_42240 4abd2352f03f9065443957410b03b7a9 381 Gene3D G3DSA:1.10.10.10 93 141 1.5E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_42240 4abd2352f03f9065443957410b03b7a9 381 SUPERFAMILY SSF88946 2 63 7.85E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_29940 f6a89e905889be1dd31107709d37dc38 289 Pfam PF01513 ATP-NAD kinase 49 264 2.7E-57 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_29940 f6a89e905889be1dd31107709d37dc38 289 Gene3D G3DSA:2.60.200.30 120 256 2.7E-86 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_29940 f6a89e905889be1dd31107709d37dc38 289 Hamap MF_00361 NAD kinase [nadK]. 12 279 27.816 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFR_29940 f6a89e905889be1dd31107709d37dc38 289 Gene3D G3DSA:3.40.50.10330 51 277 2.7E-86 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_29940 f6a89e905889be1dd31107709d37dc38 289 SUPERFAMILY SSF111331 1 285 3.92E-76 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_01060 fbc52069743bd24fa5313aecb515a3fa 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 129 4.5E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_01060 fbc52069743bd24fa5313aecb515a3fa 135 SUPERFAMILY SSF54593 1 132 9.35E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_01060 fbc52069743bd24fa5313aecb515a3fa 135 Gene3D G3DSA:3.10.180.10 2 134 4.2E-33 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_00450 79b2f95a0f633888eded5715caa3a5e7 114 Pfam PF01638 HxlR-like helix-turn-helix 15 101 7.6E-28 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_00450 79b2f95a0f633888eded5715caa3a5e7 114 Gene3D G3DSA:1.10.10.10 1 113 2.9E-44 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00450 79b2f95a0f633888eded5715caa3a5e7 114 SUPERFAMILY SSF46785 3 113 5.47E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_31795 ec0e14c204a1e9d25558b4bd0544b433 329 SUPERFAMILY SSF53448 6 224 2.36E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_31795 ec0e14c204a1e9d25558b4bd0544b433 329 Pfam PF00535 Glycosyl transferase family 2 16 136 1.6E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_31795 ec0e14c204a1e9d25558b4bd0544b433 329 Gene3D G3DSA:3.90.550.10 4 261 6.1E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_07530 891977a125be02260b75d30e0a8309c9 254 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 194 235 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_07530 891977a125be02260b75d30e0a8309c9 254 Gene3D G3DSA:1.10.10.60 146 243 1.3E-21 T 12-10-2018 AFR_07530 891977a125be02260b75d30e0a8309c9 254 Pfam PF12833 Helix-turn-helix domain 163 240 9.2E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_07530 891977a125be02260b75d30e0a8309c9 254 SMART SM00342 157 239 1.0E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_07530 891977a125be02260b75d30e0a8309c9 254 SUPERFAMILY SSF46689 146 191 1.34E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_19535 ad36ccd568483655c3f7aeea536f0e4b 115 Pfam PF13190 PDGLE domain 15 105 3.8E-22 T 12-10-2018 IPR025937 PDGLE domain AFR_19535 ad36ccd568483655c3f7aeea536f0e4b 115 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 24 109 2.0E-6 T 12-10-2018 AFR_32710 4f9238cec336f69f9ba36238b8aeed67 327 Gene3D G3DSA:1.10.510.10 143 256 3.2E-7 T 12-10-2018 AFR_32710 4f9238cec336f69f9ba36238b8aeed67 327 SUPERFAMILY SSF56112 147 229 7.79E-11 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_26835 42e8df3d4277c55abba2ece457ad79d1 424 SUPERFAMILY SSF52266 212 419 1.15E-40 T 12-10-2018 AFR_26835 42e8df3d4277c55abba2ece457ad79d1 424 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 217 413 1.0E-22 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_26835 42e8df3d4277c55abba2ece457ad79d1 424 Gene3D G3DSA:3.40.50.1110 188 421 9.2E-34 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_35940 5bf05a800af89950112713e811f41010 149 Gene3D G3DSA:1.10.10.10 2 147 7.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_35940 5bf05a800af89950112713e811f41010 149 SUPERFAMILY SSF46785 7 146 3.16E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26890 a0529536c26a31f626229d5bf5e28a74 183 Gene3D G3DSA:3.40.50.850 5 178 5.4E-38 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_26890 a0529536c26a31f626229d5bf5e28a74 183 SUPERFAMILY SSF52499 4 144 1.31E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_26890 a0529536c26a31f626229d5bf5e28a74 183 Pfam PF00857 Isochorismatase family 10 141 1.2E-32 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_13445 c9094661c6fb9c76309bf1e57df321cb 144 Pfam PF03259 Roadblock/LC7 domain 13 104 8.2E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_13445 c9094661c6fb9c76309bf1e57df321cb 144 SUPERFAMILY SSF103196 8 133 2.79E-27 T 12-10-2018 AFR_13445 c9094661c6fb9c76309bf1e57df321cb 144 SMART SM00960 14 104 2.8E-25 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_13445 c9094661c6fb9c76309bf1e57df321cb 144 Gene3D G3DSA:3.30.450.30 9 135 6.1E-41 T 12-10-2018 AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 SUPERFAMILY SSF51445 4 485 6.14E-157 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 SMART SM00642 13 428 1.3E-160 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 Gene3D G3DSA:3.20.20.80 5 480 8.6E-196 T 12-10-2018 AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 SUPERFAMILY SSF51011 489 561 1.38E-13 T 12-10-2018 AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 Pfam PF11941 Domain of unknown function (DUF3459) 472 560 1.5E-9 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 Gene3D G3DSA:2.60.40.1180 490 562 1.3E-16 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 Pfam PF00128 Alpha amylase, catalytic domain 28 384 1.9E-115 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFR_33005 22d2a3623bf2b970ac8065d93d17bfa6 565 Gene3D G3DSA:3.90.400.10 105 181 8.6E-196 T 12-10-2018 AFR_35110 465fb6c67c2d9a1c08842662e022bb69 342 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 19 265 1.3E-70 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain AFR_35110 465fb6c67c2d9a1c08842662e022bb69 342 Gene3D G3DSA:3.90.920.30 26 303 2.9E-90 T 12-10-2018 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 Gene3D G3DSA:1.10.240.10 202 307 8.2E-99 T 12-10-2018 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 SUPERFAMILY SSF52374 19 338 3.62E-78 T 12-10-2018 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 Pfam PF00579 tRNA synthetases class I (W and Y) 18 294 7.8E-55 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 31 47 4.7E-26 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 82 101 4.7E-26 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 159 180 4.7E-26 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 209 219 4.7E-26 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 18 338 1.9E-73 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 27 36 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFR_42480 2e44e252e37a5da538489853c1f9c407 341 Gene3D G3DSA:3.40.50.620 20 338 8.2E-99 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_00270 cf2d2407fa176cb1ae6854cdfdecce45 160 Gene3D G3DSA:2.60.200.20 52 159 5.2E-26 T 12-10-2018 AFR_00270 cf2d2407fa176cb1ae6854cdfdecce45 160 SUPERFAMILY SSF49879 65 158 6.12E-24 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 AFR_00270 cf2d2407fa176cb1ae6854cdfdecce45 160 SMART SM00240 87 137 9.7E-13 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFR_00270 cf2d2407fa176cb1ae6854cdfdecce45 160 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 71 159 2.3E-14 T 12-10-2018 IPR032030 YscD, cytoplasmic domain AFR_28535 52b4ec2e0e1c1fcb1ad0b4942864f6de 194 Gene3D G3DSA:3.10.620.30 1 149 4.7E-17 T 12-10-2018 AFR_28535 52b4ec2e0e1c1fcb1ad0b4942864f6de 194 SUPERFAMILY SSF54001 22 135 2.52E-21 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_28535 52b4ec2e0e1c1fcb1ad0b4942864f6de 194 Pfam PF01841 Transglutaminase-like superfamily 26 130 5.8E-12 T 12-10-2018 IPR002931 Transglutaminase-like AFR_07655 790915ab1459dfd03a5bfa52e755af53 114 Gene3D G3DSA:3.30.750.24 5 113 1.9E-16 T 12-10-2018 IPR036513 STAS domain superfamily AFR_07655 790915ab1459dfd03a5bfa52e755af53 114 SUPERFAMILY SSF52091 8 97 2.75E-13 T 12-10-2018 IPR036513 STAS domain superfamily AFR_07655 790915ab1459dfd03a5bfa52e755af53 114 Pfam PF01740 STAS domain 16 100 3.9E-12 T 12-10-2018 IPR002645 STAS domain AFR_02265 c9e97bdb2689c10c6c9aead92043e8d2 238 Gene3D G3DSA:1.10.150.240 13 109 1.1E-52 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_02265 c9e97bdb2689c10c6c9aead92043e8d2 238 Gene3D G3DSA:3.40.50.1000 5 236 1.1E-52 T 12-10-2018 IPR023214 HAD superfamily AFR_02265 c9e97bdb2689c10c6c9aead92043e8d2 238 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 2 209 3.3E-48 T 12-10-2018 IPR010976 Beta-phosphoglucomutase hydrolase AFR_02265 c9e97bdb2689c10c6c9aead92043e8d2 238 Pfam PF00702 haloacid dehalogenase-like hydrolase 2 205 2.2E-12 T 12-10-2018 AFR_02265 c9e97bdb2689c10c6c9aead92043e8d2 238 SUPERFAMILY SSF56784 2 237 1.62E-36 T 12-10-2018 IPR036412 HAD-like superfamily AFR_02265 c9e97bdb2689c10c6c9aead92043e8d2 238 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 209 8.4E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_00065 61881a2df848c2955dc69a6d54b1b684 180 Pfam PF12728 Helix-turn-helix domain 8 55 3.9E-7 T 12-10-2018 AFR_21100 e923a2cf394afaddf5da4a04db39c641 163 Pfam PF13411 MerR HTH family regulatory protein 3 68 2.2E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21100 e923a2cf394afaddf5da4a04db39c641 163 SUPERFAMILY SSF46955 3 85 4.76E-14 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_21100 e923a2cf394afaddf5da4a04db39c641 163 SMART SM00422 3 70 4.7E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21100 e923a2cf394afaddf5da4a04db39c641 163 Gene3D G3DSA:1.10.1660.10 2 70 2.5E-13 T 12-10-2018 AFR_15345 3ba0c3eacd47d42d604cbdee87657dd2 328 SUPERFAMILY SSF50129 11 152 7.67E-33 T 12-10-2018 IPR011032 GroES-like superfamily AFR_15345 3ba0c3eacd47d42d604cbdee87657dd2 328 SMART SM00829 20 322 2.7E-13 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_15345 3ba0c3eacd47d42d604cbdee87657dd2 328 Pfam PF13602 Zinc-binding dehydrogenase 200 322 3.0E-22 T 12-10-2018 AFR_15345 3ba0c3eacd47d42d604cbdee87657dd2 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 38 99 2.1E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_15345 3ba0c3eacd47d42d604cbdee87657dd2 328 SUPERFAMILY SSF51735 130 299 4.52E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15345 3ba0c3eacd47d42d604cbdee87657dd2 328 Gene3D G3DSA:3.40.50.720 141 273 7.0E-78 T 12-10-2018 AFR_15345 3ba0c3eacd47d42d604cbdee87657dd2 328 Gene3D G3DSA:3.90.180.10 28 322 7.0E-78 T 12-10-2018 AFR_08530 91fea67879bbe77503ec1441b0677cdd 439 Pfam PF01882 Protein of unknown function DUF58 192 277 7.1E-19 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_30530 a9207435467c39b1dc3a63e06d4c14ee 225 Gene3D G3DSA:3.20.20.70 1 218 5.3E-84 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_30530 a9207435467c39b1dc3a63e06d4c14ee 225 SUPERFAMILY SSF51366 5 216 2.06E-67 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_30530 a9207435467c39b1dc3a63e06d4c14ee 225 PIRSF PIRSF001461 1 225 4.6E-89 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFR_30530 a9207435467c39b1dc3a63e06d4c14ee 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 7 215 4.3E-79 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFR_30530 a9207435467c39b1dc3a63e06d4c14ee 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFR_30530 a9207435467c39b1dc3a63e06d4c14ee 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 202 1.1E-75 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFR_36085 5a5acaba90d7732ffed93bb3086551b0 467 Gene3D G3DSA:3.40.710.10 28 328 3.5E-53 T 12-10-2018 AFR_36085 5a5acaba90d7732ffed93bb3086551b0 467 SUPERFAMILY SSF56601 36 323 7.93E-47 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_36085 5a5acaba90d7732ffed93bb3086551b0 467 Pfam PF00144 Beta-lactamase 41 323 1.1E-40 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_39100 dfeb44615d3e979e98a6aefb80f8877b 125 Gene3D G3DSA:3.40.50.450 1 116 2.0E-24 T 12-10-2018 AFR_39100 dfeb44615d3e979e98a6aefb80f8877b 125 Pfam PF15891 Nucleoside 2-deoxyribosyltransferase like 2 85 3.5E-11 T 12-10-2018 IPR039470 Nucleoside 2-deoxyribosyltransferase-like AFR_30405 af417e278a18a2a79255222cd0038a1a 152 SUPERFAMILY SSF46785 14 146 5.9E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_30405 af417e278a18a2a79255222cd0038a1a 152 Gene3D G3DSA:1.10.10.10 4 146 1.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_37535 d4c407620cfdf62e308e7c7f3f3fd980 189 SUPERFAMILY SSF52540 2 181 2.5E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37535 d4c407620cfdf62e308e7c7f3f3fd980 189 Gene3D G3DSA:3.40.50.300 1 182 2.8E-10 T 12-10-2018 AFR_36210 6c1529b4e7daa42cd50cd9c850256624 254 Pfam PF00696 Amino acid kinase family 24 231 1.7E-28 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFR_36210 6c1529b4e7daa42cd50cd9c850256624 254 Hamap MF_01220_B Uridylate kinase [pyrH]. 20 253 40.831 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFR_36210 6c1529b4e7daa42cd50cd9c850256624 254 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 23 253 8.2E-86 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFR_36210 6c1529b4e7daa42cd50cd9c850256624 254 PIRSF PIRSF005650 18 254 3.4E-85 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AFR_36210 6c1529b4e7daa42cd50cd9c850256624 254 SUPERFAMILY SSF53633 23 253 8.12E-67 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_36210 6c1529b4e7daa42cd50cd9c850256624 254 Gene3D G3DSA:3.40.1160.10 14 254 3.0E-75 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 SUPERFAMILY SSF52172 3 184 2.8E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 3.4E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 SMART SM00421 152 209 1.6E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 SMART SM00448 3 116 1.3E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 Pfam PF00072 Response regulator receiver domain 5 116 1.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 8.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 8.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 8.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_35090 9952786a99a28c368c527cad20bc7ec9 222 Gene3D G3DSA:3.40.50.12740 3 215 2.4E-69 T 12-10-2018 AFR_37160 65c20d51741ee60009793f1964a25d18 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 5.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37160 65c20d51741ee60009793f1964a25d18 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 5.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37160 65c20d51741ee60009793f1964a25d18 189 Gene3D G3DSA:1.10.357.10 4 189 2.5E-43 T 12-10-2018 AFR_37160 65c20d51741ee60009793f1964a25d18 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 6.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_37160 65c20d51741ee60009793f1964a25d18 189 SUPERFAMILY SSF46689 11 78 1.6E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_37160 65c20d51741ee60009793f1964a25d18 189 SUPERFAMILY SSF48498 88 189 2.4E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_42155 e3ca4b9ac87cb1bf51f425bb84d4599f 135 SMART SM00345 24 83 1.1E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_42155 e3ca4b9ac87cb1bf51f425bb84d4599f 135 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 5.3E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_42155 e3ca4b9ac87cb1bf51f425bb84d4599f 135 SUPERFAMILY SSF46785 14 86 5.22E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_42155 e3ca4b9ac87cb1bf51f425bb84d4599f 135 Gene3D G3DSA:1.10.10.10 18 132 1.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03965 de9088ead44073a2cf15aaccc35a6b95 123 Gene3D G3DSA:1.25.40.10 2 123 8.1E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_03965 de9088ead44073a2cf15aaccc35a6b95 123 SUPERFAMILY SSF48452 7 110 2.02E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_03965 de9088ead44073a2cf15aaccc35a6b95 123 Pfam PF14559 Tetratricopeptide repeat 15 78 9.9E-13 T 12-10-2018 AFR_39770 0c46a32af232b24795ffc00f989cf3ff 231 SUPERFAMILY SSF48498 109 219 1.41E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_39770 0c46a32af232b24795ffc00f989cf3ff 231 ProSitePatterns PS01081 TetR-type HTH domain signature. 54 84 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_39770 0c46a32af232b24795ffc00f989cf3ff 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 86 2.2E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39770 0c46a32af232b24795ffc00f989cf3ff 231 SUPERFAMILY SSF46689 29 108 1.33E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_39770 0c46a32af232b24795ffc00f989cf3ff 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 3.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39770 0c46a32af232b24795ffc00f989cf3ff 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 3.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_39770 0c46a32af232b24795ffc00f989cf3ff 231 Gene3D G3DSA:1.10.357.10 25 224 4.1E-48 T 12-10-2018 AFR_07440 26295f6ad2bb4b4fc4af0123659e3b8d 264 Pfam PF04203 Sortase family 118 258 1.2E-16 T 12-10-2018 IPR005754 Sortase family AFR_07440 26295f6ad2bb4b4fc4af0123659e3b8d 264 SUPERFAMILY SSF63817 106 260 1.24E-15 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_07440 26295f6ad2bb4b4fc4af0123659e3b8d 264 Gene3D G3DSA:2.40.260.10 110 262 1.7E-25 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_09415 1ee822d8e5fd9d9732803c1d8af3bfb2 322 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 40 277 1.0E-77 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related AFR_38055 ed7f1b97e6675f0e5629516222ed9dad 296 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 106 1.2E-21 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFR_38055 ed7f1b97e6675f0e5629516222ed9dad 296 Gene3D G3DSA:3.40.50.10330 1 111 1.3E-27 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFR_38055 ed7f1b97e6675f0e5629516222ed9dad 296 Gene3D G3DSA:2.60.200.40 117 289 2.4E-19 T 12-10-2018 AFR_38055 ed7f1b97e6675f0e5629516222ed9dad 296 SUPERFAMILY SSF111331 6 296 1.07E-51 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFR_14745 f928853b14bc03b66b018de74c1c132c 275 SUPERFAMILY SSF56601 21 272 2.09E-70 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_14745 f928853b14bc03b66b018de74c1c132c 275 Pfam PF13354 Beta-lactamase enzyme family 41 247 1.7E-37 T 12-10-2018 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 Gene3D G3DSA:3.40.710.10 13 274 2.4E-76 T 12-10-2018 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 PRINTS PR00118 Beta-lactamase class A signature 92 117 1.2E-60 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 PRINTS PR00118 Beta-lactamase class A signature 128 152 1.2E-60 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 PRINTS PR00118 Beta-lactamase class A signature 21 45 1.2E-60 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 PRINTS PR00118 Beta-lactamase class A signature 52 69 1.2E-60 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 PRINTS PR00118 Beta-lactamase class A signature 190 205 1.2E-60 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 PRINTS PR00118 Beta-lactamase class A signature 154 179 1.2E-60 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFR_14745 f928853b14bc03b66b018de74c1c132c 275 PRINTS PR00118 Beta-lactamase class A signature 207 222 1.2E-60 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFR_01445 cbfb7be8b9b28d50f309820d893567c5 206 Pfam PF06475 Putative glycolipid-binding 8 205 2.0E-45 T 12-10-2018 IPR009467 Putative glycolipid-binding protein AFR_01445 cbfb7be8b9b28d50f309820d893567c5 206 SUPERFAMILY SSF159275 5 206 7.85E-46 T 12-10-2018 AFR_13130 6a6f6b745bf51a68e928b40f7cae1c34 278 Gene3D G3DSA:3.90.226.10 3 278 7.3E-72 T 12-10-2018 AFR_13130 6a6f6b745bf51a68e928b40f7cae1c34 278 SUPERFAMILY SSF52096 4 227 1.97E-48 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_13130 6a6f6b745bf51a68e928b40f7cae1c34 278 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 225 1.0E-30 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SUPERFAMILY SSF141072 277 395 1.57E-15 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Gene3D G3DSA:2.60.40.2030 398 519 2.9E-18 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Gene3D G3DSA:2.60.40.2030 57 159 6.8E-11 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Gene3D G3DSA:2.60.40.2030 277 397 8.4E-14 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Gene3D G3DSA:2.60.40.2030 162 275 1.6E-17 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Pfam PF03160 Calx-beta domain 267 376 5.8E-13 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Pfam PF03160 Calx-beta domain 512 567 190.0 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Pfam PF03160 Calx-beta domain 87 139 1.3E-6 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Pfam PF03160 Calx-beta domain 150 252 6.2E-16 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Pfam PF03160 Calx-beta domain 641 741 1.3 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 Pfam PF03160 Calx-beta domain 404 493 2.8E-10 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SUPERFAMILY SSF141072 403 521 4.19E-20 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SUPERFAMILY SSF141072 524 647 9.55E-10 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SUPERFAMILY SSF141072 86 160 8.63E-11 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SMART SM00237 266 376 8.9E-4 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SMART SM00237 150 254 3.8E-11 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SMART SM00237 41 141 0.0034 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SMART SM00237 389 493 1.0E-5 T 12-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFR_33450 4ba93b1a3e2edbf7cd21b3c0e05e2b6b 961 SUPERFAMILY SSF141072 161 279 1.31E-20 T 12-10-2018 IPR038081 CalX-like domain superfamily AFR_33345 35b76a73d9d709816584638987421b4b 182 Pfam PF13302 Acetyltransferase (GNAT) domain 11 149 2.7E-17 T 12-10-2018 IPR000182 GNAT domain AFR_33345 35b76a73d9d709816584638987421b4b 182 Gene3D G3DSA:3.40.630.30 8 175 7.6E-38 T 12-10-2018 AFR_33345 35b76a73d9d709816584638987421b4b 182 SUPERFAMILY SSF55729 8 174 1.19E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_02795 db97e7b4944445ef9c268a2cead902a3 344 Pfam PF00535 Glycosyl transferase family 2 4 128 3.1E-30 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_02795 db97e7b4944445ef9c268a2cead902a3 344 SUPERFAMILY SSF53448 2 222 3.75E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02795 db97e7b4944445ef9c268a2cead902a3 344 Gene3D G3DSA:3.90.550.10 2 197 1.2E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_24670 c60fdec4d50c80878bb537ae8fa45deb 470 Gene3D G3DSA:1.20.1720.10 12 219 1.2E-56 T 12-10-2018 AFR_24670 c60fdec4d50c80878bb537ae8fa45deb 470 SUPERFAMILY SSF103473 4 455 2.09E-74 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_24670 c60fdec4d50c80878bb537ae8fa45deb 470 Gene3D G3DSA:1.20.1250.20 259 460 7.2E-21 T 12-10-2018 AFR_24670 c60fdec4d50c80878bb537ae8fa45deb 470 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 413 4.1E-88 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_24670 c60fdec4d50c80878bb537ae8fa45deb 470 Pfam PF07690 Major Facilitator Superfamily 17 408 1.4E-61 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_14615 9f6ece2184030de776db33b4b98c6102 591 Pfam PF00501 AMP-binding enzyme 16 458 1.7E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_14615 9f6ece2184030de776db33b4b98c6102 591 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_14615 9f6ece2184030de776db33b4b98c6102 591 Gene3D G3DSA:3.40.50.12780 313 451 5.8E-34 T 12-10-2018 AFR_14615 9f6ece2184030de776db33b4b98c6102 591 Gene3D G3DSA:3.40.50.12780 2 311 9.4E-53 T 12-10-2018 AFR_14615 9f6ece2184030de776db33b4b98c6102 591 SUPERFAMILY SSF56801 7 589 2.35E-114 T 12-10-2018 AFR_17900 639919385ab74ba959154ca88ea1ae4e 242 Pfam PF01553 Acyltransferase 61 185 1.1E-25 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_17900 639919385ab74ba959154ca88ea1ae4e 242 SUPERFAMILY SSF69593 13 236 1.57E-39 T 12-10-2018 AFR_17900 639919385ab74ba959154ca88ea1ae4e 242 SMART SM00563 75 188 3.7E-35 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_05675 75ab096ddc71ea85e811a7b0f7075d64 121 Pfam PF12005 Protein of unknown function (DUF3499) 5 118 1.3E-47 T 12-10-2018 IPR021888 Protein of unknown function DUF3499 AFR_02140 b0f8459e371f0bb48d2e7bd74fa55457 436 Pfam PF05977 Transmembrane secretion effector 4 403 1.6E-47 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_02140 b0f8459e371f0bb48d2e7bd74fa55457 436 Gene3D G3DSA:1.20.1250.20 7 397 6.9E-35 T 12-10-2018 AFR_02140 b0f8459e371f0bb48d2e7bd74fa55457 436 SUPERFAMILY SSF103473 12 399 1.14E-38 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_19800 165a6b1e173d5cb0b6191b9245982c22 143 SUPERFAMILY SSF88697 4 139 2.04E-36 T 12-10-2018 IPR015947 PUA-like superfamily AFR_19800 165a6b1e173d5cb0b6191b9245982c22 143 Pfam PF04266 ASCH domain 19 136 1.5E-17 T 12-10-2018 IPR007374 ASCH domain AFR_19800 165a6b1e173d5cb0b6191b9245982c22 143 Gene3D G3DSA:3.10.400.10 2 142 2.2E-45 T 12-10-2018 AFR_19800 165a6b1e173d5cb0b6191b9245982c22 143 SMART SM01022 11 137 3.6E-32 T 12-10-2018 IPR007374 ASCH domain AFR_19800 165a6b1e173d5cb0b6191b9245982c22 143 PIRSF PIRSF021320 2 140 2.2E-43 T 12-10-2018 IPR009326 Protein of unknown function DUF984 AFR_39910 b9d6d010ba0e6997eda370ca1b429f57 201 SUPERFAMILY SSF100950 14 191 5.58E-38 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_39910 b9d6d010ba0e6997eda370ca1b429f57 201 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 15 189 3.7E-30 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFR_39910 b9d6d010ba0e6997eda370ca1b429f57 201 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 15 189 1.1E-34 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFR_39910 b9d6d010ba0e6997eda370ca1b429f57 201 PIRSF PIRSF006806 11 192 8.5E-29 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFR_39910 b9d6d010ba0e6997eda370ca1b429f57 201 Gene3D G3DSA:3.40.50.10420 14 199 1.6E-37 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFR_08500 27ada2c475b2f3c7299147703aa2363f 140 Gene3D G3DSA:3.90.190.10 33 140 2.5E-18 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFR_08500 27ada2c475b2f3c7299147703aa2363f 140 SUPERFAMILY SSF52799 36 139 2.12E-20 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFR_41960 f354a8d55c9f9706c991b5e1bc820bf1 183 Pfam PF03029 Conserved hypothetical ATP binding protein 7 143 5.1E-20 T 12-10-2018 IPR004130 GPN-loop GTPase AFR_41960 f354a8d55c9f9706c991b5e1bc820bf1 183 SUPERFAMILY SSF52540 2 175 1.22E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_41960 f354a8d55c9f9706c991b5e1bc820bf1 183 Gene3D G3DSA:3.40.50.300 1 179 4.9E-13 T 12-10-2018 AFR_38555 4cf9079bf9359df53280456a1e2ac9ba 137 SMART SM00342 21 104 1.9E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_38555 4cf9079bf9359df53280456a1e2ac9ba 137 SUPERFAMILY SSF46689 6 54 2.69E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_38555 4cf9079bf9359df53280456a1e2ac9ba 137 SUPERFAMILY SSF46689 57 107 8.96E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_38555 4cf9079bf9359df53280456a1e2ac9ba 137 Pfam PF12833 Helix-turn-helix domain 27 106 3.2E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_38555 4cf9079bf9359df53280456a1e2ac9ba 137 Gene3D G3DSA:1.10.10.60 2 110 7.2E-29 T 12-10-2018 AFR_26395 6fc26c4554afede850c58a9511d9c924 304 Gene3D G3DSA:3.90.25.10 182 294 7.4E-82 T 12-10-2018 AFR_26395 6fc26c4554afede850c58a9511d9c924 304 Gene3D G3DSA:3.40.50.720 3 286 7.4E-82 T 12-10-2018 AFR_26395 6fc26c4554afede850c58a9511d9c924 304 SUPERFAMILY SSF51735 1 300 3.44E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_26395 6fc26c4554afede850c58a9511d9c924 304 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 287 7.4E-44 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_03845 8fca49d0bafaa1019d071167400fd336 122 Pfam PF13581 Histidine kinase-like ATPase domain 16 105 1.2E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_03845 8fca49d0bafaa1019d071167400fd336 122 SUPERFAMILY SSF55874 28 121 7.44E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_03845 8fca49d0bafaa1019d071167400fd336 122 Gene3D G3DSA:3.30.565.10 3 121 4.4E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38910 278aec585866221406aed19abc440e61 225 Gene3D G3DSA:1.10.1660.10 2 50 9.7E-9 T 12-10-2018 AFR_38910 278aec585866221406aed19abc440e61 225 Pfam PF12728 Helix-turn-helix domain 5 46 2.3E-6 T 12-10-2018 AFR_38910 278aec585866221406aed19abc440e61 225 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 44 2.7E-8 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_07345 670a427c9e4f11675694c8926bbaae9d 195 Gene3D G3DSA:1.20.120.450 10 137 3.7E-14 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_07345 670a427c9e4f11675694c8926bbaae9d 195 SUPERFAMILY SSF109854 12 140 2.27E-20 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_07345 670a427c9e4f11675694c8926bbaae9d 195 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 134 5.0E-14 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_07345 670a427c9e4f11675694c8926bbaae9d 195 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 14 189 9.4E-44 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 AFR_07345 670a427c9e4f11675694c8926bbaae9d 195 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 156 1.5E-22 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_13965 49cf5a7c8839c201759e286a0ca53efd 241 Gene3D G3DSA:1.10.260.40 18 92 7.7E-8 T 12-10-2018 AFR_13965 49cf5a7c8839c201759e286a0ca53efd 241 Gene3D G3DSA:3.30.450.180 94 241 4.0E-10 T 12-10-2018 AFR_13965 49cf5a7c8839c201759e286a0ca53efd 241 Pfam PF13560 Helix-turn-helix domain 2 79 1.6E-15 T 12-10-2018 AFR_13965 49cf5a7c8839c201759e286a0ca53efd 241 SMART SM00530 4 76 3.8E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_13965 49cf5a7c8839c201759e286a0ca53efd 241 SUPERFAMILY SSF47413 22 75 6.26E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_20670 2028a65a22bddaf6039f3cb4e32eae08 231 Gene3D G3DSA:1.10.357.10 39 230 7.0E-41 T 12-10-2018 AFR_20670 2028a65a22bddaf6039f3cb4e32eae08 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 91 1.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_20670 2028a65a22bddaf6039f3cb4e32eae08 231 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 119 227 3.4E-12 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_20670 2028a65a22bddaf6039f3cb4e32eae08 231 SUPERFAMILY SSF46689 43 116 1.18E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_20670 2028a65a22bddaf6039f3cb4e32eae08 231 SUPERFAMILY SSF48498 117 229 5.34E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_24360 3eca395d677c29c3f490653068a52077 156 SUPERFAMILY SSF46785 46 136 4.72E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_24360 3eca395d677c29c3f490653068a52077 156 Gene3D G3DSA:1.10.10.10 17 156 2.7E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_24360 3eca395d677c29c3f490653068a52077 156 Pfam PF12802 MarR family 47 93 2.8E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_40570 84e4a02573c473577459b28e5412fc5d 128 SMART SM00448 1 116 4.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40570 84e4a02573c473577459b28e5412fc5d 128 Pfam PF00072 Response regulator receiver domain 4 116 4.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40570 84e4a02573c473577459b28e5412fc5d 128 SUPERFAMILY SSF52172 2 118 8.54E-31 T 12-10-2018 IPR011006 CheY-like superfamily AFR_40570 84e4a02573c473577459b28e5412fc5d 128 Gene3D G3DSA:3.40.50.12740 1 124 4.2E-32 T 12-10-2018 AFR_01730 651123bfc462c22c5ef0fb9cbd7781bd 377 Pfam PF07690 Major Facilitator Superfamily 16 183 5.3E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_01730 651123bfc462c22c5ef0fb9cbd7781bd 377 Pfam PF07690 Major Facilitator Superfamily 198 362 2.3E-8 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_01730 651123bfc462c22c5ef0fb9cbd7781bd 377 SUPERFAMILY SSF103473 7 368 6.8E-42 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_01730 651123bfc462c22c5ef0fb9cbd7781bd 377 Gene3D G3DSA:1.20.1250.20 188 368 1.2E-12 T 12-10-2018 AFR_01730 651123bfc462c22c5ef0fb9cbd7781bd 377 Gene3D G3DSA:1.20.1250.20 2 182 3.3E-22 T 12-10-2018 AFR_16840 a4d7691fc6317d23d9ca0f3c87ec85fb 327 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 230 2.4E-12 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 AFR_16840 a4d7691fc6317d23d9ca0f3c87ec85fb 327 Gene3D G3DSA:3.40.50.720 3 308 1.8E-78 T 12-10-2018 AFR_16840 a4d7691fc6317d23d9ca0f3c87ec85fb 327 SUPERFAMILY SSF55347 130 297 3.27E-28 T 12-10-2018 AFR_16840 a4d7691fc6317d23d9ca0f3c87ec85fb 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 112 2.5E-24 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_16840 a4d7691fc6317d23d9ca0f3c87ec85fb 327 SUPERFAMILY SSF51735 3 154 3.31E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16840 a4d7691fc6317d23d9ca0f3c87ec85fb 327 Gene3D G3DSA:3.30.360.10 129 323 1.8E-78 T 12-10-2018 AFR_30330 91599a62e6fbdc3d2e741b666d152e7a 305 Gene3D G3DSA:1.10.510.10 197 256 6.0E-17 T 12-10-2018 AFR_30330 91599a62e6fbdc3d2e741b666d152e7a 305 Gene3D G3DSA:1.20.58.840 142 302 6.0E-17 T 12-10-2018 AFR_30330 91599a62e6fbdc3d2e741b666d152e7a 305 Pfam PF01636 Phosphotransferase enzyme family 28 264 1.5E-12 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_30330 91599a62e6fbdc3d2e741b666d152e7a 305 SUPERFAMILY SSF56112 6 267 1.07E-16 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_13880 ebf87edf0b296ba75420234f7d0857d3 357 Pfam PF01266 FAD dependent oxidoreductase 1 334 4.2E-45 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_13880 ebf87edf0b296ba75420234f7d0857d3 357 SUPERFAMILY SSF54373 196 294 6.54E-12 T 12-10-2018 AFR_13880 ebf87edf0b296ba75420234f7d0857d3 357 SUPERFAMILY SSF51905 1 356 1.55E-18 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_13880 ebf87edf0b296ba75420234f7d0857d3 357 Gene3D G3DSA:3.30.9.10 63 294 2.0E-52 T 12-10-2018 AFR_13880 ebf87edf0b296ba75420234f7d0857d3 357 Gene3D G3DSA:3.50.50.60 1 334 2.0E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_15995 a89142959c29b89106d796960d2e4bb1 426 Pfam PF13692 Glycosyl transferases group 1 213 359 9.0E-19 T 12-10-2018 AFR_15995 a89142959c29b89106d796960d2e4bb1 426 SUPERFAMILY SSF53756 22 397 7.85E-49 T 12-10-2018 AFR_15995 a89142959c29b89106d796960d2e4bb1 426 Pfam PF13579 Glycosyl transferase 4-like domain 29 191 4.5E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_15995 a89142959c29b89106d796960d2e4bb1 426 Gene3D G3DSA:3.40.50.2000 20 196 1.6E-9 T 12-10-2018 AFR_15995 a89142959c29b89106d796960d2e4bb1 426 Gene3D G3DSA:3.40.50.2000 197 374 1.8E-25 T 12-10-2018 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 Gene3D G3DSA:1.25.40.20 167 343 8.9E-29 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 Gene3D G3DSA:1.25.40.20 1 166 2.5E-39 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 PRINTS PR01415 Ankyrin repeat signature 66 81 8.9E-5 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 PRINTS PR01415 Ankyrin repeat signature 115 129 8.9E-5 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SUPERFAMILY SSF48403 3 330 1.18E-43 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 Pfam PF12796 Ankyrin repeats (3 copies) 63 129 6.2E-11 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 Pfam PF12796 Ankyrin repeats (3 copies) 3 58 1.5E-6 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 Pfam PF12796 Ankyrin repeats (3 copies) 238 305 8.7E-7 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SMART SM00248 202 231 0.41 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SMART SM00248 276 305 0.003 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SMART SM00248 99 128 0.11 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SMART SM00248 236 267 320.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SMART SM00248 65 94 7.2E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SMART SM00248 31 60 0.0036 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_12350 ecd82f3d22eaaec239ed65951687c5a8 344 SMART SM00248 309 344 4100.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFR_09780 9a1f998c3a8477197eb69245e033a3e6 185 Gene3D G3DSA:3.40.50.300 1 178 9.8E-40 T 12-10-2018 AFR_09780 9a1f998c3a8477197eb69245e033a3e6 185 SUPERFAMILY SSF52540 1 175 4.79E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29245 241407adf57bb02026d11ed96b9e0471 186 Gene3D G3DSA:1.10.357.10 3 130 2.9E-7 T 12-10-2018 AFR_29245 241407adf57bb02026d11ed96b9e0471 186 SUPERFAMILY SSF46689 4 61 2.67E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_23800 b93f518bfd342aef386fc7c0f7dbcc34 216 SUPERFAMILY SSF51569 2 212 3.24E-44 T 12-10-2018 AFR_23800 b93f518bfd342aef386fc7c0f7dbcc34 216 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 207 6.4E-27 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFR_23800 b93f518bfd342aef386fc7c0f7dbcc34 216 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFR_23800 b93f518bfd342aef386fc7c0f7dbcc34 216 Gene3D G3DSA:3.20.20.70 1 215 6.0E-58 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 Gene3D G3DSA:3.50.50.60 8 312 8.4E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.6E-35 T 12-10-2018 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 1.6E-35 T 12-10-2018 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.6E-35 T 12-10-2018 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 1.6E-35 T 12-10-2018 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.6E-35 T 12-10-2018 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 SUPERFAMILY SSF51905 6 311 6.83E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 135 147 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 202 218 1.4E-79 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 Gene3D G3DSA:3.50.50.60 124 247 8.4E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 142 162 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 302 3.9E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_42930 9b96dd16b882a2ee11d5a372a7701f4e 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 313 3.7E-120 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 AFR_31320 a347c0514472af11f7ba94944993a008 398 Gene3D G3DSA:3.40.50.2000 187 366 7.5E-104 T 12-10-2018 AFR_31320 a347c0514472af11f7ba94944993a008 398 Pfam PF00534 Glycosyl transferases group 1 201 356 1.1E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_31320 a347c0514472af11f7ba94944993a008 398 Pfam PF13579 Glycosyl transferase 4-like domain 22 186 2.0E-29 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_31320 a347c0514472af11f7ba94944993a008 398 SUPERFAMILY SSF53756 20 388 7.42E-81 T 12-10-2018 AFR_31320 a347c0514472af11f7ba94944993a008 398 Gene3D G3DSA:3.40.50.2000 5 383 7.5E-104 T 12-10-2018 AFR_34305 1890566a7d165807c4b23190aa196240 182 Pfam PF04542 Sigma-70 region 2 24 91 6.6E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34305 1890566a7d165807c4b23190aa196240 182 SUPERFAMILY SSF88659 119 178 2.18E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_34305 1890566a7d165807c4b23190aa196240 182 Gene3D G3DSA:1.10.1740.10 1 108 1.9E-22 T 12-10-2018 AFR_34305 1890566a7d165807c4b23190aa196240 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 178 1.3E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_34305 1890566a7d165807c4b23190aa196240 182 Gene3D G3DSA:1.10.10.10 117 180 6.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34305 1890566a7d165807c4b23190aa196240 182 SUPERFAMILY SSF88946 2 107 1.55E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_34305 1890566a7d165807c4b23190aa196240 182 Pfam PF08281 Sigma-70, region 4 119 173 4.2E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_37635 ba1eb2cf6dad4c8166a6c5951fd6ccf1 114 Gene3D G3DSA:3.10.180.10 1 112 5.1E-13 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_37635 ba1eb2cf6dad4c8166a6c5951fd6ccf1 114 SUPERFAMILY SSF54593 2 110 1.93E-15 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_30750 ab34efed21782013d7c07aea5152f20a 425 Pfam PF07690 Major Facilitator Superfamily 27 371 2.7E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_30750 ab34efed21782013d7c07aea5152f20a 425 SUPERFAMILY SSF103473 14 406 8.89E-32 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_30750 ab34efed21782013d7c07aea5152f20a 425 Gene3D G3DSA:1.20.1250.20 7 405 4.9E-26 T 12-10-2018 AFR_23920 a549ea4fc066a4a07c6edfbaf59dd7ac 135 Pfam PF03795 YCII-related domain 20 109 2.3E-12 T 12-10-2018 IPR005545 YCII-related AFR_23920 a549ea4fc066a4a07c6edfbaf59dd7ac 135 SUPERFAMILY SSF54909 21 125 1.82E-23 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_23920 a549ea4fc066a4a07c6edfbaf59dd7ac 135 Gene3D G3DSA:3.30.70.1060 2 128 5.3E-26 T 12-10-2018 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.0E-9 T 12-10-2018 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.0E-9 T 12-10-2018 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 1.0E-9 T 12-10-2018 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.0E-9 T 12-10-2018 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 Pfam PF07690 Major Facilitator Superfamily 13 409 1.5E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 Gene3D G3DSA:1.20.1250.20 197 431 1.1E-17 T 12-10-2018 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 Gene3D G3DSA:1.20.1250.20 8 196 7.4E-42 T 12-10-2018 AFR_42030 ce2130edf513104b30e1596be1c2fada 519 SUPERFAMILY SSF103473 9 493 1.96E-61 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_01245 3ccbcc54fcf56a3e9d4d8bdcf338278e 229 SMART SM00382 29 217 2.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01245 3ccbcc54fcf56a3e9d4d8bdcf338278e 229 Gene3D G3DSA:3.40.50.300 4 222 5.2E-61 T 12-10-2018 AFR_01245 3ccbcc54fcf56a3e9d4d8bdcf338278e 229 Pfam PF00005 ABC transporter 20 168 5.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01245 3ccbcc54fcf56a3e9d4d8bdcf338278e 229 SUPERFAMILY SSF52540 6 218 4.8E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11300 bca49fe10c05184764d2d590f82b9369 461 SUPERFAMILY SSF55874 361 454 8.86E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_11300 bca49fe10c05184764d2d590f82b9369 461 Pfam PF07730 Histidine kinase 257 323 1.5E-20 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_11300 bca49fe10c05184764d2d590f82b9369 461 Gene3D G3DSA:3.30.565.10 330 455 1.3E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_15220 4e41f51e19c4ebb7095fa51f1ce24e25 298 Gene3D G3DSA:2.120.10.30 2 296 1.0E-45 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_15220 4e41f51e19c4ebb7095fa51f1ce24e25 298 SUPERFAMILY SSF63829 3 294 3.43E-49 T 12-10-2018 AFR_15220 4e41f51e19c4ebb7095fa51f1ce24e25 298 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 264 1.0E-40 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region AFR_15220 4e41f51e19c4ebb7095fa51f1ce24e25 298 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 249 267 1.0E-6 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_15220 4e41f51e19c4ebb7095fa51f1ce24e25 298 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 208 225 1.0E-6 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_15220 4e41f51e19c4ebb7095fa51f1ce24e25 298 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 89 110 1.0E-6 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) AFR_27805 2cff0615d82f25d7890f592dc3c663bc 404 SUPERFAMILY SSF51905 2 374 1.94E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27805 2cff0615d82f25d7890f592dc3c663bc 404 Pfam PF01266 FAD dependent oxidoreductase 2 354 3.4E-52 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_27805 2cff0615d82f25d7890f592dc3c663bc 404 Gene3D G3DSA:3.50.50.60 2 355 4.8E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_27805 2cff0615d82f25d7890f592dc3c663bc 404 Gene3D G3DSA:3.30.9.10 93 317 4.8E-67 T 12-10-2018 AFR_31530 0f31e1041e800623d71267b8e717658f 450 Pfam PF01979 Amidohydrolase family 56 388 4.0E-58 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_31530 0f31e1041e800623d71267b8e717658f 450 SUPERFAMILY SSF51338 2 447 1.11E-19 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_31530 0f31e1041e800623d71267b8e717658f 450 SUPERFAMILY SSF51556 59 373 5.11E-95 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_31530 0f31e1041e800623d71267b8e717658f 450 Gene3D G3DSA:2.30.40.10 11 422 1.7E-123 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_31530 0f31e1041e800623d71267b8e717658f 450 Gene3D G3DSA:3.20.20.140 60 373 1.7E-123 T 12-10-2018 AFR_42470 ab278d45b15f814d1e37832930ea4803 258 Pfam PF00005 ABC transporter 31 172 2.1E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_42470 ab278d45b15f814d1e37832930ea4803 258 SMART SM00382 38 220 5.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_42470 ab278d45b15f814d1e37832930ea4803 258 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_42470 ab278d45b15f814d1e37832930ea4803 258 SUPERFAMILY SSF52540 12 235 6.84E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42470 ab278d45b15f814d1e37832930ea4803 258 Gene3D G3DSA:3.40.50.300 4 250 2.6E-53 T 12-10-2018 AFR_19750 3a512a63ddef8e0aabfcba59fd1975be 261 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 108 130 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_19750 3a512a63ddef8e0aabfcba59fd1975be 261 Pfam PF01066 CDP-alcohol phosphatidyltransferase 63 130 5.6E-9 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_19750 3a512a63ddef8e0aabfcba59fd1975be 261 Gene3D G3DSA:1.20.120.1760 54 218 7.7E-8 T 12-10-2018 AFR_31110 44eea6a2d2b76523ede35655fc4fe9c8 301 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 13 295 1.0E-50 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFR_31660 d3f42d714f7683fcc935d958fefe994b 319 Pfam PF09754 PAC2 family 44 260 7.5E-48 T 12-10-2018 IPR019151 Proteasome assembly chaperone 2 AFR_31660 d3f42d714f7683fcc935d958fefe994b 319 Gene3D G3DSA:1.10.287.100 242 280 6.5E-90 T 12-10-2018 AFR_31660 d3f42d714f7683fcc935d958fefe994b 319 PIRSF PIRSF028754 25 319 2.5E-97 T 12-10-2018 IPR008492 Protein of unknown function DUF774 AFR_31660 d3f42d714f7683fcc935d958fefe994b 319 SUPERFAMILY SSF159659 24 285 1.96E-86 T 12-10-2018 AFR_31660 d3f42d714f7683fcc935d958fefe994b 319 Gene3D G3DSA:3.40.50.10900 38 241 6.5E-90 T 12-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily AFR_03630 46a0d05cf4455472d4e5caf8ea1c9313 267 Pfam PF00884 Sulfatase 9 248 3.0E-12 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 AFR_03630 46a0d05cf4455472d4e5caf8ea1c9313 267 SUPERFAMILY SSF53649 10 257 2.62E-21 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_03630 46a0d05cf4455472d4e5caf8ea1c9313 267 Gene3D G3DSA:3.40.720.10 6 258 1.9E-18 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_21820 480fe315879063ff4c2bb0ad7816a66b 352 Gene3D G3DSA:3.40.50.720 197 309 4.7E-11 T 12-10-2018 AFR_21820 480fe315879063ff4c2bb0ad7816a66b 352 SUPERFAMILY SSF51735 174 335 1.58E-9 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_21820 480fe315879063ff4c2bb0ad7816a66b 352 Gene3D G3DSA:3.90.180.10 8 196 2.3E-7 T 12-10-2018 AFR_21820 480fe315879063ff4c2bb0ad7816a66b 352 SUPERFAMILY SSF50129 27 167 3.54E-6 T 12-10-2018 IPR011032 GroES-like superfamily AFR_23730 cf509c4924c3c9951032546b19ad5076 443 PIRSF PIRSF000521 123 431 2.3E-28 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_23730 cf509c4924c3c9951032546b19ad5076 443 PIRSF PIRSF000521 18 128 1.6E-5 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_23730 cf509c4924c3c9951032546b19ad5076 443 SUPERFAMILY SSF53383 6 430 7.61E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_23730 cf509c4924c3c9951032546b19ad5076 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_23730 cf509c4924c3c9951032546b19ad5076 443 Gene3D G3DSA:3.40.640.10 59 323 3.4E-143 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_23730 cf509c4924c3c9951032546b19ad5076 443 Gene3D G3DSA:3.90.1150.10 30 423 3.4E-143 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_23730 cf509c4924c3c9951032546b19ad5076 443 Pfam PF00202 Aminotransferase class-III 26 428 3.9E-89 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFR_26135 1778a9199ddbbd3b7b734f8908d48ad7 242 Gene3D G3DSA:3.30.450.40 71 239 4.2E-41 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_26135 1778a9199ddbbd3b7b734f8908d48ad7 242 Pfam PF09339 IclR helix-turn-helix domain 2 46 7.8E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_26135 1778a9199ddbbd3b7b734f8908d48ad7 242 SUPERFAMILY SSF46785 2 67 3.09E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_26135 1778a9199ddbbd3b7b734f8908d48ad7 242 SUPERFAMILY SSF55781 62 236 1.5E-37 T 12-10-2018 AFR_26135 1778a9199ddbbd3b7b734f8908d48ad7 242 Pfam PF01614 Bacterial transcriptional regulator 113 228 7.7E-25 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFR_26135 1778a9199ddbbd3b7b734f8908d48ad7 242 Gene3D G3DSA:1.10.10.10 1 67 3.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26135 1778a9199ddbbd3b7b734f8908d48ad7 242 SMART SM00346 1 84 5.3E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFR_17760 b690ffc4b1765766a1d16e479422da5b 244 Pfam PF00149 Calcineurin-like phosphoesterase 20 165 7.1E-6 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_17760 b690ffc4b1765766a1d16e479422da5b 244 SUPERFAMILY SSF56300 1 205 2.85E-22 T 12-10-2018 AFR_17760 b690ffc4b1765766a1d16e479422da5b 244 Gene3D G3DSA:3.60.21.10 1 242 6.3E-35 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_39550 07ac4b0b864aff51de35ed104f4c11d9 355 SUPERFAMILY SSF51556 8 339 2.31E-75 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_39550 07ac4b0b864aff51de35ed104f4c11d9 355 Gene3D G3DSA:3.20.20.140 8 352 8.3E-103 T 12-10-2018 AFR_39550 07ac4b0b864aff51de35ed104f4c11d9 355 Pfam PF00962 Adenosine/AMP deaminase 12 343 1.6E-88 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 AFR_39550 07ac4b0b864aff51de35ed104f4c11d9 355 Hamap MF_00540 Adenosine deaminase [add]. 7 346 53.823 T 12-10-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 AFR_39550 07ac4b0b864aff51de35ed104f4c11d9 355 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 13 343 5.4E-76 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 AFR_34130 7c2af51c82605c819711a6073a7dcce3 112 Pfam PF01638 HxlR-like helix-turn-helix 10 98 7.5E-25 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_34130 7c2af51c82605c819711a6073a7dcce3 112 Gene3D G3DSA:1.10.10.10 7 109 8.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34130 7c2af51c82605c819711a6073a7dcce3 112 SUPERFAMILY SSF46785 9 106 3.84E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20305 691b621c21d5fc1c781e23ed372c84cc 310 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_20305 691b621c21d5fc1c781e23ed372c84cc 310 SMART SM00382 30 244 1.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20305 691b621c21d5fc1c781e23ed372c84cc 310 Pfam PF00005 ABC transporter 22 166 9.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20305 691b621c21d5fc1c781e23ed372c84cc 310 Gene3D G3DSA:3.40.50.300 2 260 2.8E-55 T 12-10-2018 AFR_20305 691b621c21d5fc1c781e23ed372c84cc 310 SUPERFAMILY SSF52540 4 228 2.09E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24120 e54f688320a50ba0df36dcd261f03f30 681 Pfam PF02652 L-lactate permease 426 671 1.1E-60 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFR_24120 e54f688320a50ba0df36dcd261f03f30 681 Pfam PF02652 L-lactate permease 21 291 5.3E-75 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFR_34715 167e584ef58510319259fe633dc39e19 249 Gene3D G3DSA:3.40.50.10490 2 242 6.9E-72 T 12-10-2018 AFR_34715 167e584ef58510319259fe633dc39e19 249 SUPERFAMILY SSF53697 10 212 3.03E-21 T 12-10-2018 AFR_34715 167e584ef58510319259fe633dc39e19 249 Pfam PF13580 SIS domain 7 146 9.8E-41 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_10320 ddcb8a284d34d6e0e50e25ca07a3157d 360 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 274 15.329 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_10320 ddcb8a284d34d6e0e50e25ca07a3157d 360 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 268 6.0E-61 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_10320 ddcb8a284d34d6e0e50e25ca07a3157d 360 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 12 265 6.8E-42 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_10320 ddcb8a284d34d6e0e50e25ca07a3157d 360 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFR_25710 a4ad303c00f831d8dddfaaf7a66a70b2 95 SUPERFAMILY SSF54909 3 72 2.95E-9 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_25710 a4ad303c00f831d8dddfaaf7a66a70b2 95 Pfam PF03992 Antibiotic biosynthesis monooxygenase 23 65 3.1E-5 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_15065 966d3ad442ab9ba4303ea9d37c661de1 242 Pfam PF12679 ABC-2 family transporter protein 64 234 2.7E-10 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_42390 30b62c9e21124bcc90d84ce90671f0fc 364 Gene3D G3DSA:3.90.1150.10 4 358 1.1E-107 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_42390 30b62c9e21124bcc90d84ce90671f0fc 364 Pfam PF00155 Aminotransferase class I and II 7 355 1.2E-38 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_42390 30b62c9e21124bcc90d84ce90671f0fc 364 Gene3D G3DSA:3.40.640.10 41 255 1.1E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_42390 30b62c9e21124bcc90d84ce90671f0fc 364 SUPERFAMILY SSF53383 5 361 2.85E-89 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_08210 cc71ee1130e4b2b400f9d9d74e034604 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 74 338 3.5E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_08945 e669eb38b5f3788cd92f21e8f10b7c37 83 Gene3D G3DSA:1.10.268.10 2 80 2.3E-5 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFR_24415 02e73871dbec4cb5c03a77a2ef1bc69e 258 Gene3D G3DSA:3.40.50.300 1 216 1.6E-60 T 12-10-2018 AFR_24415 02e73871dbec4cb5c03a77a2ef1bc69e 258 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_24415 02e73871dbec4cb5c03a77a2ef1bc69e 258 Pfam PF00005 ABC transporter 24 159 1.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_24415 02e73871dbec4cb5c03a77a2ef1bc69e 258 SMART SM00382 31 221 4.0E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_24415 02e73871dbec4cb5c03a77a2ef1bc69e 258 SUPERFAMILY SSF52540 7 208 1.21E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42410 3c0ba53f2983ed1772081aa8c9224a87 506 SUPERFAMILY SSF101908 172 500 1.96E-5 T 12-10-2018 AFR_42410 3c0ba53f2983ed1772081aa8c9224a87 506 Pfam PF14269 Arylsulfotransferase (ASST) 119 398 2.3E-54 T 12-10-2018 IPR039535 Arylsulfotransferase-like AFR_02405 45ded22a205879041269eeb715149bd9 370 Pfam PF03080 Neprosin 163 355 5.4E-26 T 12-10-2018 IPR004314 Neprosin AFR_11600 e5dd6e89e5e9cb2e598d65bcc1285af4 226 SMART SM00014 97 207 4.5E-17 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_11600 e5dd6e89e5e9cb2e598d65bcc1285af4 226 SUPERFAMILY SSF48317 13 209 9.42E-29 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_11600 e5dd6e89e5e9cb2e598d65bcc1285af4 226 Pfam PF01569 PAP2 superfamily 98 211 4.6E-20 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_11600 e5dd6e89e5e9cb2e598d65bcc1285af4 226 Gene3D G3DSA:1.20.144.10 124 223 1.3E-18 T 12-10-2018 AFR_25775 c71cbb6ef7b9501a00ff37e4f91dc6ae 418 Pfam PF00563 EAL domain 6 229 3.8E-34 T 12-10-2018 IPR001633 EAL domain AFR_25775 c71cbb6ef7b9501a00ff37e4f91dc6ae 418 SMART SM00052 1 234 2.5E-14 T 12-10-2018 IPR001633 EAL domain AFR_25775 c71cbb6ef7b9501a00ff37e4f91dc6ae 418 Gene3D G3DSA:3.20.20.450 2 234 7.9E-43 T 12-10-2018 IPR035919 EAL domain superfamily AFR_25775 c71cbb6ef7b9501a00ff37e4f91dc6ae 418 Pfam PF10069 Sensory domain in DIguanylate Cyclases and Two-component system 270 369 5.5E-10 T 12-10-2018 IPR019278 DICT domain AFR_25775 c71cbb6ef7b9501a00ff37e4f91dc6ae 418 SUPERFAMILY SSF141868 3 233 8.76E-45 T 12-10-2018 IPR035919 EAL domain superfamily AFR_02115 84c5b703b3c16efaef8ff9b86ac409e6 625 Pfam PF07690 Major Facilitator Superfamily 74 409 5.6E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_02115 84c5b703b3c16efaef8ff9b86ac409e6 625 SUPERFAMILY SSF103473 69 447 3.4E-18 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_02115 84c5b703b3c16efaef8ff9b86ac409e6 625 Gene3D G3DSA:1.20.1250.20 58 446 8.8E-17 T 12-10-2018 AFR_22680 cce71c72838d4ba99dfc52f0f1b1b6e2 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 8 95 5.9E-6 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 AFR_16275 f5bbb3f591e451b378687ad139067d92 245 Pfam PF11150 Protein of unknown function (DUF2927) 53 241 9.9E-25 T 12-10-2018 IPR021323 Protein of unknown function DUF2927 AFR_07760 c615c9c50a0dd92743f8f6f33f11d8ef 663 Pfam PF00753 Metallo-beta-lactamase superfamily 418 582 9.7E-10 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_07760 c615c9c50a0dd92743f8f6f33f11d8ef 663 SUPERFAMILY SSF56281 404 650 2.62E-34 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_07760 c615c9c50a0dd92743f8f6f33f11d8ef 663 Pfam PF03772 Competence protein 109 372 2.3E-51 T 12-10-2018 IPR004477 ComEC/Rec2-related protein AFR_07760 c615c9c50a0dd92743f8f6f33f11d8ef 663 Gene3D G3DSA:3.60.15.10 409 648 2.5E-51 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_07760 c615c9c50a0dd92743f8f6f33f11d8ef 663 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 131 300 1.9E-15 T 12-10-2018 IPR004477 ComEC/Rec2-related protein AFR_07760 c615c9c50a0dd92743f8f6f33f11d8ef 663 SMART SM00849 416 612 0.0051 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_38070 efc737395817902b3ec1e823e95e2bce 254 Gene3D G3DSA:3.40.50.620 28 254 1.6E-69 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFR_38070 efc737395817902b3ec1e823e95e2bce 254 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 68 229 1.5E-43 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFR_38070 efc737395817902b3ec1e823e95e2bce 254 SUPERFAMILY SSF52402 39 218 5.44E-45 T 12-10-2018 AFR_38070 efc737395817902b3ec1e823e95e2bce 254 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 47 253 6.9E-60 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFR_38070 efc737395817902b3ec1e823e95e2bce 254 PIRSF PIRSF000857 18 254 3.8E-87 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFR_04485 bd80b5b374bfaac74984573b7d3287bd 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.7E-58 T 12-10-2018 IPR023798 Ribosomal protein S7 domain AFR_04485 bd80b5b374bfaac74984573b7d3287bd 156 Gene3D G3DSA:1.10.455.10 2 156 9.4E-56 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AFR_04485 bd80b5b374bfaac74984573b7d3287bd 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFR_04485 bd80b5b374bfaac74984573b7d3287bd 156 SUPERFAMILY SSF47973 1 149 2.09E-56 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AFR_04485 bd80b5b374bfaac74984573b7d3287bd 156 PIRSF PIRSF002122 5 156 1.1E-53 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 AFR_04485 bd80b5b374bfaac74984573b7d3287bd 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.286 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFR_04485 bd80b5b374bfaac74984573b7d3287bd 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.1E-63 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFR_04405 bd3b4b3895383feeabc9fff2dd436bc1 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFR_04405 bd3b4b3895383feeabc9fff2dd436bc1 55 SUPERFAMILY SSF57829 3 55 3.66E-20 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFR_04405 bd3b4b3895383feeabc9fff2dd436bc1 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 5 55 9.7E-23 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04405 bd3b4b3895383feeabc9fff2dd436bc1 55 Gene3D G3DSA:2.20.28.120 3 55 1.5E-25 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04405 bd3b4b3895383feeabc9fff2dd436bc1 55 Pfam PF00471 Ribosomal protein L33 10 55 3.9E-24 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_04405 bd3b4b3895383feeabc9fff2dd436bc1 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 19.772 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_25790 c02c8ab8bad5f925ad74e3e8dbf8ab05 429 Pfam PF00463 Isocitrate lyase family 255 424 9.6E-43 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFR_25790 c02c8ab8bad5f925ad74e3e8dbf8ab05 429 Pfam PF00463 Isocitrate lyase family 18 253 9.0E-52 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFR_25790 c02c8ab8bad5f925ad74e3e8dbf8ab05 429 PIRSF PIRSF001362 2 429 8.3E-231 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFR_25790 c02c8ab8bad5f925ad74e3e8dbf8ab05 429 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 14 253 4.5E-105 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFR_25790 c02c8ab8bad5f925ad74e3e8dbf8ab05 429 ProSitePatterns PS00161 Isocitrate lyase signature. 191 196 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 AFR_25790 c02c8ab8bad5f925ad74e3e8dbf8ab05 429 SUPERFAMILY SSF51621 13 429 1.79E-154 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_25790 c02c8ab8bad5f925ad74e3e8dbf8ab05 429 Gene3D G3DSA:3.20.20.60 12 413 3.4E-167 T 12-10-2018 AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 Gene3D G3DSA:1.10.10.10 9 72 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 SUPERFAMILY SSF48008 78 211 6.8E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 SMART SM00895 81 203 6.5E-10 T 12-10-2018 IPR011711 GntR, C-terminal AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 Pfam PF07729 FCD domain 81 198 8.8E-13 T 12-10-2018 IPR011711 GntR, C-terminal AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 1.9E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 SMART SM00345 13 71 6.9E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 SUPERFAMILY SSF46785 9 75 9.85E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_34850 fe9360cf36ca68058cef1719e6ec7f86 213 Gene3D G3DSA:1.20.120.530 75 213 1.9E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFR_19705 336ed51f5120e7545ec8ce4a492bac95 449 SUPERFAMILY SSF53474 68 420 2.05E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19705 336ed51f5120e7545ec8ce4a492bac95 449 Pfam PF00561 alpha/beta hydrolase fold 71 419 1.2E-27 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_05815 7384db94c219b00daaa2ae428eb1aff0 140 SMART SM00450 22 119 9.7E-15 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_05815 7384db94c219b00daaa2ae428eb1aff0 140 Gene3D G3DSA:3.40.250.10 4 121 4.4E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_05815 7384db94c219b00daaa2ae428eb1aff0 140 Pfam PF00581 Rhodanese-like domain 34 115 2.0E-12 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_05815 7384db94c219b00daaa2ae428eb1aff0 140 SUPERFAMILY SSF52821 20 122 1.3E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_29465 3eb6eb34a83b0d3f3f62fd89e8bf0add 142 Pfam PF12802 MarR family 21 81 1.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29465 3eb6eb34a83b0d3f3f62fd89e8bf0add 142 Gene3D G3DSA:1.10.10.10 1 134 1.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29465 3eb6eb34a83b0d3f3f62fd89e8bf0add 142 SMART SM00347 15 118 4.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_29465 3eb6eb34a83b0d3f3f62fd89e8bf0add 142 SUPERFAMILY SSF46785 16 125 1.55E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15125 b1b19056d2ba20871c2e99ddb85cb8e5 201 SUPERFAMILY SSF46689 4 84 2.14E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15125 b1b19056d2ba20871c2e99ddb85cb8e5 201 Gene3D G3DSA:1.10.357.10 2 200 4.1E-42 T 12-10-2018 AFR_15125 b1b19056d2ba20871c2e99ddb85cb8e5 201 SUPERFAMILY SSF48498 86 197 8.58E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_15125 b1b19056d2ba20871c2e99ddb85cb8e5 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 8.5E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15125 b1b19056d2ba20871c2e99ddb85cb8e5 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15125 b1b19056d2ba20871c2e99ddb85cb8e5 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_15125 b1b19056d2ba20871c2e99ddb85cb8e5 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_20120 57bcbb40db603347fae53f9cd883929c 368 Pfam PF03583 Secretory lipase 116 368 8.7E-20 T 12-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 AFR_20120 57bcbb40db603347fae53f9cd883929c 368 SUPERFAMILY SSF53474 59 362 7.11E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20120 57bcbb40db603347fae53f9cd883929c 368 PIRSF PIRSF029171 16 368 1.1E-69 T 12-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 AFR_20120 57bcbb40db603347fae53f9cd883929c 368 Gene3D G3DSA:3.40.50.1820 29 223 6.6E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_20120 57bcbb40db603347fae53f9cd883929c 368 Gene3D G3DSA:3.40.50.1820 278 368 6.6E-10 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28180 b7caa4dc78ffba1bd98de769c6091a72 112 Pfam PF05656 Protein of unknown function (DUF805) 11 111 3.1E-28 T 12-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 AFR_01745 cd005342a70e03a7cabbf74448b96f8a 236 Pfam PF13490 Putative zinc-finger 11 35 1.6E-6 T 12-10-2018 IPR027383 Putative zinc-finger AFR_01745 cd005342a70e03a7cabbf74448b96f8a 236 Gene3D G3DSA:1.10.10.1320 4 64 8.4E-23 T 12-10-2018 AFR_33265 98b03cd864b255a425b7330061aab959 268 Pfam PF13367 Protease prsW family 66 241 3.2E-27 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 60 78 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 Pfam PF01022 Bacterial regulatory protein, arsR family 41 89 1.9E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 1.9E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 1.9E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 1.9E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 69 1.9E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 SMART SM00418 34 115 5.0E-28 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 Gene3D G3DSA:1.10.10.10 18 122 4.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_00590 59bf1f6084e224f4fc79e7ea87acd8cd 125 SUPERFAMILY SSF46785 24 114 3.79E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_20625 a5e983a968e79368afb368e529b97ea3 331 Pfam PF03741 Integral membrane protein TerC family 70 272 6.1E-51 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFR_20625 a5e983a968e79368afb368e529b97ea3 331 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 310 6.3E-108 T 12-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 AFR_18040 f0e76c6623a40c2605216b77e3206588 588 SUPERFAMILY SSF53850 116 342 1.41E-5 T 12-10-2018 AFR_18040 f0e76c6623a40c2605216b77e3206588 588 Gene3D G3DSA:3.40.50.410 389 585 2.5E-27 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_18040 f0e76c6623a40c2605216b77e3206588 588 SUPERFAMILY SSF53300 389 580 3.71E-21 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_18040 f0e76c6623a40c2605216b77e3206588 588 Pfam PF00092 von Willebrand factor type A domain 391 578 3.4E-13 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_18040 f0e76c6623a40c2605216b77e3206588 588 SMART SM00327 387 582 6.1E-11 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_18040 f0e76c6623a40c2605216b77e3206588 588 Pfam PF13531 Bacterial extracellular solute-binding protein 51 330 1.2E-24 T 12-10-2018 AFR_33835 8fd5ee9fddd1d10a3130f016481f6939 145 SUPERFAMILY SSF50475 5 144 2.07E-15 T 12-10-2018 AFR_33835 8fd5ee9fddd1d10a3130f016481f6939 145 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 87 8.4E-5 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_33835 8fd5ee9fddd1d10a3130f016481f6939 145 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 144 6.8E-27 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_33835 8fd5ee9fddd1d10a3130f016481f6939 145 Gene3D G3DSA:2.30.110.10 3 145 1.4E-23 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_11415 bdd8c3cbe4323a74e0b7ac8e1c1878f2 134 Pfam PF12680 SnoaL-like domain 20 123 2.3E-8 T 12-10-2018 IPR037401 SnoaL-like domain AFR_11415 bdd8c3cbe4323a74e0b7ac8e1c1878f2 134 Gene3D G3DSA:3.10.450.50 3 134 3.3E-23 T 12-10-2018 AFR_11415 bdd8c3cbe4323a74e0b7ac8e1c1878f2 134 SUPERFAMILY SSF54427 6 131 1.26E-18 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_16030 ea9625c1edf4fe1b86cd4ec717fe2b5f 295 Pfam PF00483 Nucleotidyl transferase 4 236 5.7E-65 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFR_16030 ea9625c1edf4fe1b86cd4ec717fe2b5f 295 SUPERFAMILY SSF53448 3 286 2.93E-84 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16030 ea9625c1edf4fe1b86cd4ec717fe2b5f 295 Gene3D G3DSA:3.90.550.10 1 292 6.6E-82 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16030 ea9625c1edf4fe1b86cd4ec717fe2b5f 295 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 3 286 1.4E-133 T 12-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AFR_21110 d1fb2cb6de8e8dc904ba5a940c99b2ef 206 SUPERFAMILY SSF53335 3 195 1.38E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_21110 d1fb2cb6de8e8dc904ba5a940c99b2ef 206 Gene3D G3DSA:3.40.50.150 6 201 5.6E-44 T 12-10-2018 AFR_21110 d1fb2cb6de8e8dc904ba5a940c99b2ef 206 Pfam PF13649 Methyltransferase domain 39 130 6.0E-18 T 12-10-2018 AFR_13675 b5d649fadc54d89092693c31377a4552 180 Gene3D G3DSA:3.30.530.20 2 147 1.8E-48 T 12-10-2018 IPR023393 START-like domain superfamily AFR_13675 b5d649fadc54d89092693c31377a4552 180 SUPERFAMILY SSF55961 3 142 7.78E-28 T 12-10-2018 AFR_13675 b5d649fadc54d89092693c31377a4552 180 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 133 9.4E-15 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 AFR_34970 2c29aa206cf78718948ba567b28f4381 155 SUPERFAMILY SSF55729 1 141 5.06E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_34970 2c29aa206cf78718948ba567b28f4381 155 Gene3D G3DSA:3.40.630.30 4 139 2.4E-22 T 12-10-2018 AFR_34970 2c29aa206cf78718948ba567b28f4381 155 Pfam PF13673 Acetyltransferase (GNAT) domain 44 150 1.6E-16 T 12-10-2018 IPR000182 GNAT domain AFR_25055 cce0e0329127da041e46a9ab420a411e 298 SUPERFAMILY SSF56112 36 245 3.74E-17 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_25055 cce0e0329127da041e46a9ab420a411e 298 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 33 264 2.7E-24 T 12-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 AFR_25055 cce0e0329127da041e46a9ab420a411e 298 Gene3D G3DSA:3.90.1200.10 119 238 3.1E-6 T 12-10-2018 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 Gene3D G3DSA:3.40.190.80 167 258 6.7E-10 T 12-10-2018 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 Pfam PF00459 Inositol monophosphatase family 17 232 9.9E-36 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 2.6E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 2.6E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 2.6E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 2.6E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 SUPERFAMILY SSF56655 2 258 1.26E-50 T 12-10-2018 AFR_26270 705105e068b79500ccd416f7cb5b0409 260 Gene3D G3DSA:3.30.540.10 1 138 1.5E-34 T 12-10-2018 AFR_24050 cd419d7e6253a27542786945727f60b7 331 Pfam PF12679 ABC-2 family transporter protein 55 214 3.8E-7 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_22545 953c186859dde8c592de14fba7e855fa 295 SUPERFAMILY SSF53697 3 289 1.07E-37 T 12-10-2018 AFR_22545 953c186859dde8c592de14fba7e855fa 295 Gene3D G3DSA:3.40.50.10490 171 238 8.4E-13 T 12-10-2018 AFR_22545 953c186859dde8c592de14fba7e855fa 295 Gene3D G3DSA:3.40.50.10490 2 154 6.1E-23 T 12-10-2018 AFR_22545 953c186859dde8c592de14fba7e855fa 295 Gene3D G3DSA:3.40.50.10490 239 291 2.1E-5 T 12-10-2018 AFR_05380 22e4752f62663fc729e387ba92013a79 336 SUPERFAMILY SSF52540 27 296 5.19E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_05380 22e4752f62663fc729e387ba92013a79 336 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 48 178 9.0E-63 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_05380 22e4752f62663fc729e387ba92013a79 336 Gene3D G3DSA:1.10.8.300 210 318 1.1E-31 T 12-10-2018 AFR_05380 22e4752f62663fc729e387ba92013a79 336 Gene3D G3DSA:3.40.50.300 29 195 5.4E-45 T 12-10-2018 AFR_05380 22e4752f62663fc729e387ba92013a79 336 PIRSF PIRSF002849 10 323 2.7E-130 T 12-10-2018 AFR_16805 2b3edfdb55e3f9aa9f8f5760d7d3ba3b 268 PIRSF PIRSF017393 1 268 4.3E-94 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_16805 2b3edfdb55e3f9aa9f8f5760d7d3ba3b 268 Gene3D G3DSA:3.40.50.150 1 268 5.4E-101 T 12-10-2018 AFR_16805 2b3edfdb55e3f9aa9f8f5760d7d3ba3b 268 SUPERFAMILY SSF53335 17 252 8.46E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_16805 2b3edfdb55e3f9aa9f8f5760d7d3ba3b 268 Pfam PF04672 S-adenosyl methyltransferase 9 268 4.2E-101 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_14635 0abf4e7ad8af63ee164bd5e855f03f0b 226 SUPERFAMILY SSF53474 13 189 1.08E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14635 0abf4e7ad8af63ee164bd5e855f03f0b 226 Gene3D G3DSA:3.40.50.1820 18 156 2.4E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14635 0abf4e7ad8af63ee164bd5e855f03f0b 226 Pfam PF12697 Alpha/beta hydrolase family 31 164 1.5E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_29380 81737bd4b2c1ba94ad75594837910b4f 40 Pfam PF01797 Transposase IS200 like 4 35 2.2E-6 T 12-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 AFR_29380 81737bd4b2c1ba94ad75594837910b4f 40 SUPERFAMILY SSF143422 4 36 1.12E-7 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFR_29380 81737bd4b2c1ba94ad75594837910b4f 40 Gene3D G3DSA:3.30.70.1290 1 39 4.9E-6 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFR_08455 8bf4d9b3ffb058b98382005c006c1d97 523 Pfam PF00171 Aldehyde dehydrogenase family 55 496 5.7E-86 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFR_08455 8bf4d9b3ffb058b98382005c006c1d97 523 SUPERFAMILY SSF53720 40 495 8.77E-76 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFR_08455 8bf4d9b3ffb058b98382005c006c1d97 523 Gene3D G3DSA:3.40.309.10 270 474 3.8E-76 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFR_08455 8bf4d9b3ffb058b98382005c006c1d97 523 Gene3D G3DSA:3.40.605.10 55 492 3.8E-76 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFR_30995 65075ed657950e04976ffd41c99060fa 407 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 39 395 3.4E-173 T 12-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like AFR_30995 65075ed657950e04976ffd41c99060fa 407 SUPERFAMILY SSF53822 38 398 6.8E-104 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_30995 65075ed657950e04976ffd41c99060fa 407 Gene3D G3DSA:3.40.50.2300 154 386 8.7E-146 T 12-10-2018 AFR_30995 65075ed657950e04976ffd41c99060fa 407 Pfam PF13433 Periplasmic binding protein domain 39 397 3.0E-151 T 12-10-2018 AFR_30995 65075ed657950e04976ffd41c99060fa 407 Gene3D G3DSA:3.40.50.2300 41 367 8.7E-146 T 12-10-2018 AFR_04380 37bfc96c0e85e7af478173e7b243d3f8 164 SUPERFAMILY SSF89963 92 164 3.92E-24 T 12-10-2018 IPR036183 YajQ-like superfamily AFR_04380 37bfc96c0e85e7af478173e7b243d3f8 164 Gene3D G3DSA:3.30.70.860 6 164 3.6E-58 T 12-10-2018 IPR035571 UPF0234-like, C-terminal AFR_04380 37bfc96c0e85e7af478173e7b243d3f8 164 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 164 24.485 T 12-10-2018 IPR007551 Protein of unknown function DUF520 AFR_04380 37bfc96c0e85e7af478173e7b243d3f8 164 Pfam PF04461 Protein of unknown function (DUF520) 5 164 4.8E-59 T 12-10-2018 IPR007551 Protein of unknown function DUF520 AFR_04380 37bfc96c0e85e7af478173e7b243d3f8 164 SUPERFAMILY SSF89963 5 89 1.52E-23 T 12-10-2018 IPR036183 YajQ-like superfamily AFR_04380 37bfc96c0e85e7af478173e7b243d3f8 164 Gene3D G3DSA:3.30.70.990 12 101 3.6E-58 T 12-10-2018 IPR035570 UPF0234, N-terminal AFR_07350 b23394f2432623714b1d787b98b6f6ee 716 Pfam PF00912 Transglycosylase 73 258 1.3E-60 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_07350 b23394f2432623714b1d787b98b6f6ee 716 Gene3D G3DSA:3.40.710.10 313 714 1.0E-78 T 12-10-2018 AFR_07350 b23394f2432623714b1d787b98b6f6ee 716 Pfam PF00905 Penicillin binding protein transpeptidase domain 364 684 4.0E-28 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_07350 b23394f2432623714b1d787b98b6f6ee 716 Gene3D G3DSA:1.10.3810.10 65 274 2.8E-71 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_07350 b23394f2432623714b1d787b98b6f6ee 716 SUPERFAMILY SSF53955 61 285 2.56E-68 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_07350 b23394f2432623714b1d787b98b6f6ee 716 SUPERFAMILY SSF56601 243 710 5.63E-77 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_01670 302c9fc80422895db0abef7319a02008 441 SUPERFAMILY SSF56762 49 441 2.49E-118 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01670 302c9fc80422895db0abef7319a02008 441 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 32 441 46.444 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01670 302c9fc80422895db0abef7319a02008 441 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 156 441 3.1E-109 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01670 302c9fc80422895db0abef7319a02008 441 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 38 441 2.8E-163 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01670 302c9fc80422895db0abef7319a02008 441 Gene3D G3DSA:1.10.645.20 38 441 5.3E-161 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_20205 d25f92849e4e9695774f0039747b0202 391 SMART SM00028 105 138 56.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_20205 d25f92849e4e9695774f0039747b0202 391 SMART SM00028 37 70 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_20205 d25f92849e4e9695774f0039747b0202 391 SMART SM00028 3 36 440.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_20205 d25f92849e4e9695774f0039747b0202 391 SMART SM00028 71 104 4.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_20205 d25f92849e4e9695774f0039747b0202 391 SMART SM00028 139 172 1.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_20205 d25f92849e4e9695774f0039747b0202 391 Pfam PF13432 Tetratricopeptide repeat 43 105 8.0E-6 T 12-10-2018 AFR_20205 d25f92849e4e9695774f0039747b0202 391 Gene3D G3DSA:1.25.40.10 4 227 4.2E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_20205 d25f92849e4e9695774f0039747b0202 391 SUPERFAMILY SSF48452 7 174 5.46E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_30700 003d148b3bb01ef3271607a862329a2e 395 Gene3D G3DSA:1.10.8.1150 73 145 7.7E-10 T 12-10-2018 AFR_30700 003d148b3bb01ef3271607a862329a2e 395 Pfam PF02618 YceG-like family 78 386 3.8E-65 T 12-10-2018 IPR003770 Endolytic murein transglycosylase AFR_30700 003d148b3bb01ef3271607a862329a2e 395 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 38 390 27.874 T 12-10-2018 IPR003770 Endolytic murein transglycosylase AFR_30700 003d148b3bb01ef3271607a862329a2e 395 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 38 387 3.0E-45 T 12-10-2018 IPR003770 Endolytic murein transglycosylase AFR_02945 3c8dc2ecd4996c53e0171ae72832e6db 342 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 208 330 3.0E-18 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFR_02945 3c8dc2ecd4996c53e0171ae72832e6db 342 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 19 323 2.2E-31 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFR_03045 99b50d2e29489e308278639e3ae38994 276 PIRSF PIRSF006648 12 276 2.2E-83 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_03045 99b50d2e29489e308278639e3ae38994 276 Pfam PF01061 ABC-2 type transporter 33 241 4.8E-33 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_24130 d3bb47fa7be9de7fa79cea07e0b9ccd9 510 PIRSF PIRSF006060 2 477 1.6E-43 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_24130 d3bb47fa7be9de7fa79cea07e0b9ccd9 510 Gene3D G3DSA:1.20.1740.10 16 467 5.2E-22 T 12-10-2018 AFR_24130 d3bb47fa7be9de7fa79cea07e0b9ccd9 510 Pfam PF00324 Amino acid permease 26 463 6.3E-20 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 AFR_13475 5af47ade2d50dead0d387c3e94f3c111 64 Gene3D G3DSA:3.20.20.100 3 63 6.2E-14 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_13475 5af47ade2d50dead0d387c3e94f3c111 64 SUPERFAMILY SSF51430 9 56 8.51E-13 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_13475 5af47ade2d50dead0d387c3e94f3c111 64 Pfam PF00248 Aldo/keto reductase family 9 51 4.0E-8 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_17420 e5e5e408730986607c16c4bc9adc8fb7 173 Gene3D G3DSA:3.40.630.30 7 172 5.7E-46 T 12-10-2018 AFR_17420 e5e5e408730986607c16c4bc9adc8fb7 173 SUPERFAMILY SSF55729 8 170 3.6E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_17420 e5e5e408730986607c16c4bc9adc8fb7 173 Pfam PF13420 Acetyltransferase (GNAT) domain 12 164 2.3E-14 T 12-10-2018 AFR_42260 ffdf547a07ed6df58e09c1f9fc2e9f3c 170 Gene3D G3DSA:3.40.50.360 1 168 3.1E-37 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_42260 ffdf547a07ed6df58e09c1f9fc2e9f3c 170 SUPERFAMILY SSF52218 2 165 1.01E-30 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_42260 ffdf547a07ed6df58e09c1f9fc2e9f3c 170 Pfam PF03358 NADPH-dependent FMN reductase 46 122 1.2E-22 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_06420 b2cfff797e6f8e0bd05fcbc894550ab2 391 PIRSF PIRSF001235 2 391 2.7E-104 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 AFR_06420 b2cfff797e6f8e0bd05fcbc894550ab2 391 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 12 387 3.3E-77 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 AFR_06420 b2cfff797e6f8e0bd05fcbc894550ab2 391 Pfam PF01546 Peptidase family M20/M25/M40 72 388 1.5E-24 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFR_06420 b2cfff797e6f8e0bd05fcbc894550ab2 391 SUPERFAMILY SSF55031 204 309 8.2E-18 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFR_06420 b2cfff797e6f8e0bd05fcbc894550ab2 391 SUPERFAMILY SSF53187 9 390 1.59E-62 T 12-10-2018 AFR_06420 b2cfff797e6f8e0bd05fcbc894550ab2 391 Gene3D G3DSA:3.40.630.10 11 384 1.0E-104 T 12-10-2018 AFR_06420 b2cfff797e6f8e0bd05fcbc894550ab2 391 Gene3D G3DSA:3.30.70.360 201 313 1.0E-104 T 12-10-2018 AFR_29025 2c234e222b6835220b7cce28ac4e16e9 135 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 10 121 6.6E-12 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 AFR_29025 2c234e222b6835220b7cce28ac4e16e9 135 SUPERFAMILY SSF53756 2 129 7.42E-30 T 12-10-2018 AFR_29025 2c234e222b6835220b7cce28ac4e16e9 135 Gene3D G3DSA:3.40.50.2000 1 121 3.4E-32 T 12-10-2018 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 SUPERFAMILY SSF55874 214 363 1.83E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 Gene3D G3DSA:3.30.565.10 210 363 1.0E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 SMART SM00387 254 364 3.1E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 362 8.9E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 SUPERFAMILY SSF47384 129 213 1.94E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 Gene3D G3DSA:1.10.287.130 95 209 7.6E-18 T 12-10-2018 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 SMART SM00304 91 144 2.0E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 361 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 319 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 305 2.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 SUPERFAMILY SSF158472 92 141 3.53E-5 T 12-10-2018 AFR_24065 66b7c5fa984c05b0f7528c1d4a99295c 364 Pfam PF00512 His Kinase A (phospho-acceptor) domain 147 211 2.3E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_22795 1a1f3afd75d364769f07a66fbc82589a 209 SUPERFAMILY SSF56112 2 185 7.95E-22 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_22795 1a1f3afd75d364769f07a66fbc82589a 209 Pfam PF01636 Phosphotransferase enzyme family 92 161 8.7E-8 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_22795 1a1f3afd75d364769f07a66fbc82589a 209 Gene3D G3DSA:3.90.1200.10 70 186 2.8E-11 T 12-10-2018 AFR_13185 4137d159b464dee954ef4a6c75f4c90a 314 Pfam PF07859 alpha/beta hydrolase fold 80 286 5.3E-66 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_13185 4137d159b464dee954ef4a6c75f4c90a 314 SUPERFAMILY SSF53474 44 309 4.79E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13185 4137d159b464dee954ef4a6c75f4c90a 314 Gene3D G3DSA:3.40.50.1820 3 311 9.7E-81 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11925 bb56f958941337e5878cb458ae4036b6 149 SMART SM00347 25 125 1.9E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11925 bb56f958941337e5878cb458ae4036b6 149 Pfam PF12802 MarR family 31 89 8.5E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11925 bb56f958941337e5878cb458ae4036b6 149 SUPERFAMILY SSF46785 14 140 5.31E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11925 bb56f958941337e5878cb458ae4036b6 149 Gene3D G3DSA:1.10.10.10 3 143 1.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03295 7e4855e02e124493dc33299bdceb7244 196 Gene3D G3DSA:3.40.50.10420 28 190 2.7E-51 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFR_03295 7e4855e02e124493dc33299bdceb7244 196 Pfam PF02589 LUD domain 99 190 1.4E-22 T 12-10-2018 IPR003741 LUD domain AFR_03295 7e4855e02e124493dc33299bdceb7244 196 SUPERFAMILY SSF100950 32 191 7.11E-34 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFR_38905 58e4a8b05440fafbfb6b0f23d625fd03 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 70 2.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_38905 58e4a8b05440fafbfb6b0f23d625fd03 200 SUPERFAMILY SSF46689 16 87 7.18E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_38905 58e4a8b05440fafbfb6b0f23d625fd03 200 Gene3D G3DSA:1.10.357.10 9 195 3.1E-12 T 12-10-2018 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 SUPERFAMILY SSF55205 14 423 1.42E-98 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 Gene3D G3DSA:3.65.10.10 27 244 3.2E-134 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 21 424 1.8E-109 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 14 418 1.1E-105 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 Gene3D G3DSA:3.65.10.10 21 416 3.2E-134 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 PIRSF PIRSF000505 7 427 1.5E-115 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_38140 cc08e113dd65e0e12d0f1b0afe66e628 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 15 426 28.418 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_22045 4138da95a786ace79f69198ea561d1b6 240 Pfam PF02585 GlcNAc-PI de-N-acetylase 36 155 1.3E-21 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 AFR_22045 4138da95a786ace79f69198ea561d1b6 240 SUPERFAMILY SSF102588 36 239 4.19E-41 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_22045 4138da95a786ace79f69198ea561d1b6 240 Gene3D G3DSA:3.40.50.10320 33 223 2.6E-37 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFR_14560 3b53f0d5947e1434e50eff76fdfbd074 281 SUPERFAMILY SSF53474 17 276 1.16E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14560 3b53f0d5947e1434e50eff76fdfbd074 281 Gene3D G3DSA:3.40.50.1820 5 280 3.8E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14560 3b53f0d5947e1434e50eff76fdfbd074 281 Pfam PF12697 Alpha/beta hydrolase family 24 270 3.9E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_33190 0629b17e87123b73156ea41af11fb80a 590 PIRSF PIRSF001589 1 589 3.0E-208 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFR_33190 0629b17e87123b73156ea41af11fb80a 590 Gene3D G3DSA:3.60.20.10 7 190 2.3E-57 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_33190 0629b17e87123b73156ea41af11fb80a 590 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 587 3.3E-290 T 12-10-2018 IPR017535 Asparagine synthase family amidotransferase AFR_33190 0629b17e87123b73156ea41af11fb80a 590 SUPERFAMILY SSF56235 1 224 6.0E-60 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_33190 0629b17e87123b73156ea41af11fb80a 590 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 519 2.7E-131 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFR_33190 0629b17e87123b73156ea41af11fb80a 590 Pfam PF00733 Asparagine synthase 242 586 1.6E-85 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFR_33190 0629b17e87123b73156ea41af11fb80a 590 Pfam PF13537 Glutamine amidotransferase domain 47 167 5.0E-42 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFR_33190 0629b17e87123b73156ea41af11fb80a 590 SUPERFAMILY SSF52402 233 569 1.19E-73 T 12-10-2018 AFR_02520 04fb5341f3dfa9f6d218064a2942b143 102 Pfam PF06013 Proteins of 100 residues with WXG 2 85 2.6E-16 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_02520 04fb5341f3dfa9f6d218064a2942b143 102 Gene3D G3DSA:1.10.287.1060 3 101 2.4E-20 T 12-10-2018 AFR_02520 04fb5341f3dfa9f6d218064a2942b143 102 SUPERFAMILY SSF140453 2 92 6.67E-18 T 12-10-2018 IPR036689 ESAT-6-like superfamily AFR_02520 04fb5341f3dfa9f6d218064a2942b143 102 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 2 90 4.5E-21 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_14500 d1fe7c61eaf9a73626a2eac5d2b28b9b 243 Gene3D G3DSA:3.30.450.40 19 167 9.5E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_14500 d1fe7c61eaf9a73626a2eac5d2b28b9b 243 Pfam PF03861 ANTAR domain 190 238 1.3E-8 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_14500 d1fe7c61eaf9a73626a2eac5d2b28b9b 243 SUPERFAMILY SSF55781 53 151 1.61E-10 T 12-10-2018 AFR_14500 d1fe7c61eaf9a73626a2eac5d2b28b9b 243 SMART SM01012 183 238 3.7E-7 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 AFR_25610 3e309a28da9fd4975dcb629066f26925 236 Gene3D G3DSA:3.40.50.300 6 231 7.5E-70 T 12-10-2018 AFR_25610 3e309a28da9fd4975dcb629066f26925 236 SMART SM00382 35 222 2.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25610 3e309a28da9fd4975dcb629066f26925 236 SUPERFAMILY SSF52540 8 227 1.3E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25610 3e309a28da9fd4975dcb629066f26925 236 Pfam PF00005 ABC transporter 26 174 4.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_25610 3e309a28da9fd4975dcb629066f26925 236 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_14825 bc65465a73aa893747add8bc3a216bdb 208 Gene3D G3DSA:1.10.357.10 1 188 9.7E-44 T 12-10-2018 AFR_14825 bc65465a73aa893747add8bc3a216bdb 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 3.8E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14825 bc65465a73aa893747add8bc3a216bdb 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_14825 bc65465a73aa893747add8bc3a216bdb 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14825 bc65465a73aa893747add8bc3a216bdb 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14825 bc65465a73aa893747add8bc3a216bdb 208 SUPERFAMILY SSF46689 9 78 4.32E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_25160 cef4ffddd12a3a0a2d0f7bd082b4f7fa 622 Pfam PF02705 K+ potassium transporter 2 542 6.6E-196 T 12-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 AFR_25160 cef4ffddd12a3a0a2d0f7bd082b4f7fa 622 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 1 622 31.112 T 12-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup AFR_09620 86ab6f9135f08e7f439bd0e64d7ccc60 204 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 46 195 3.5E-55 T 12-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain AFR_09620 86ab6f9135f08e7f439bd0e64d7ccc60 204 Gene3D G3DSA:2.30.110.10 43 204 2.3E-53 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_09620 86ab6f9135f08e7f439bd0e64d7ccc60 204 SUPERFAMILY SSF50475 48 173 1.53E-34 T 12-10-2018 AFR_13415 164d9c9d4ca8ceb492453fcd355b62e1 164 SUPERFAMILY SSF160631 23 151 3.01E-11 T 12-10-2018 AFR_13415 164d9c9d4ca8ceb492453fcd355b62e1 164 Gene3D G3DSA:3.40.1580.10 13 159 2.8E-8 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily AFR_13415 164d9c9d4ca8ceb492453fcd355b62e1 164 SMART SM00860 30 153 1.0E-5 T 12-10-2018 IPR018958 Knr4/Smi1-like domain AFR_13415 164d9c9d4ca8ceb492453fcd355b62e1 164 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 30 130 7.1E-6 T 12-10-2018 IPR018958 Knr4/Smi1-like domain AFR_12980 0991f87e4c353415ce3e2b7ec932b508 187 Gene3D G3DSA:1.10.357.10 2 187 3.8E-52 T 12-10-2018 AFR_12980 0991f87e4c353415ce3e2b7ec932b508 187 SUPERFAMILY SSF48498 83 186 6.53E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_12980 0991f87e4c353415ce3e2b7ec932b508 187 SUPERFAMILY SSF46689 9 78 2.0E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_12980 0991f87e4c353415ce3e2b7ec932b508 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 63 1.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_23075 a2b760aacdb00ad1ada1400503728524 258 PIRSF PIRSF017393 1 258 6.7E-98 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_23075 a2b760aacdb00ad1ada1400503728524 258 Gene3D G3DSA:3.40.50.150 1 258 4.4E-99 T 12-10-2018 AFR_23075 a2b760aacdb00ad1ada1400503728524 258 Pfam PF04672 S-adenosyl methyltransferase 4 258 7.5E-102 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_23075 a2b760aacdb00ad1ada1400503728524 258 SUPERFAMILY SSF53335 10 241 1.14E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_33920 96aebd34d0ca5183f3ea690f6ce5dc56 128 Pfam PF00011 Hsp20/alpha crystallin family 29 125 4.8E-17 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFR_33920 96aebd34d0ca5183f3ea690f6ce5dc56 128 SUPERFAMILY SSF49764 6 125 3.14E-28 T 12-10-2018 IPR008978 HSP20-like chaperone AFR_33920 96aebd34d0ca5183f3ea690f6ce5dc56 128 Gene3D G3DSA:2.60.40.790 2 126 1.3E-25 T 12-10-2018 IPR008978 HSP20-like chaperone AFR_18020 dd1d523d33416244f95d97d87bb9c84f 405 SUPERFAMILY SSF52266 211 403 3.82E-46 T 12-10-2018 AFR_18020 dd1d523d33416244f95d97d87bb9c84f 405 Gene3D G3DSA:3.40.50.1110 200 403 3.6E-33 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_18020 dd1d523d33416244f95d97d87bb9c84f 405 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 214 393 1.5E-24 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_10670 7c88bd3f7548bc8588ae37d36039d1ba 372 SUPERFAMILY SSF101960 22 367 1.31E-84 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily AFR_10670 7c88bd3f7548bc8588ae37d36039d1ba 372 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 92 359 4.4E-78 T 12-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 AFR_10670 7c88bd3f7548bc8588ae37d36039d1ba 372 Pfam PF01458 Uncharacterized protein family (UPF0051) 121 342 3.4E-69 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AFR_09500 e88b912dcd0f770c7e87b0f76fdac8e3 186 SUPERFAMILY SSF52833 98 182 1.63E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_09500 e88b912dcd0f770c7e87b0f76fdac8e3 186 Gene3D G3DSA:3.40.30.10 96 184 1.0E-10 T 12-10-2018 AFR_09500 e88b912dcd0f770c7e87b0f76fdac8e3 186 Pfam PF00085 Thioredoxin 98 178 8.7E-8 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFR_04705 6d542c4ca0f46ef9a63946e6bf3b3086 246 SUPERFAMILY SSF110399 4 231 2.35E-81 T 12-10-2018 AFR_04705 6d542c4ca0f46ef9a63946e6bf3b3086 246 Gene3D G3DSA:3.20.20.70 3 243 1.2E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_04705 6d542c4ca0f46ef9a63946e6bf3b3086 246 Hamap MF_00443 Thiazole synthase [thiG]. 1 245 39.104 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFR_04705 6d542c4ca0f46ef9a63946e6bf3b3086 246 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 238 1.7E-102 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 Gene3D G3DSA:3.40.50.300 5 168 4.0E-46 T 12-10-2018 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 PRINTS PR01100 Shikimate kinase family signature 95 112 2.0E-17 T 12-10-2018 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 PRINTS PR01100 Shikimate kinase family signature 75 84 2.0E-17 T 12-10-2018 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 PRINTS PR01100 Shikimate kinase family signature 57 65 2.0E-17 T 12-10-2018 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 PRINTS PR01100 Shikimate kinase family signature 29 42 2.0E-17 T 12-10-2018 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 PRINTS PR01100 Shikimate kinase family signature 5 20 2.0E-17 T 12-10-2018 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 Hamap MF_00109 Shikimate kinase [aroK]. 2 166 25.666 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 Pfam PF01202 Shikimate kinase 11 165 7.2E-40 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFR_30680 567b30992fcff1831e2c220fd3431b98 169 SUPERFAMILY SSF52540 3 164 1.8E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16380 1cbcd140fe9bf5a707f50b06f5f0ca88 225 Pfam PF02734 DAK2 domain 45 218 4.0E-53 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_16380 1cbcd140fe9bf5a707f50b06f5f0ca88 225 SMART SM01120 45 219 1.1E-74 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_16380 1cbcd140fe9bf5a707f50b06f5f0ca88 225 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 22 217 2.0E-73 T 12-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 AFR_16380 1cbcd140fe9bf5a707f50b06f5f0ca88 225 Gene3D G3DSA:1.25.40.340 7 222 2.7E-66 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_16380 1cbcd140fe9bf5a707f50b06f5f0ca88 225 SUPERFAMILY SSF101473 16 218 1.44E-54 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_17245 cfbb7aec23a9fd952706007079519111 312 SUPERFAMILY SSF55874 202 300 2.15E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17245 cfbb7aec23a9fd952706007079519111 312 Pfam PF13581 Histidine kinase-like ATPase domain 197 305 7.1E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_17245 cfbb7aec23a9fd952706007079519111 312 Gene3D G3DSA:3.30.565.10 194 312 7.8E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17245 cfbb7aec23a9fd952706007079519111 312 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 10 152 4.7E-30 T 12-10-2018 IPR025847 MEDS domain AFR_01555 feaaad084b1ccd81f6f9b77dce4d522c 140 Gene3D G3DSA:3.40.630.30 5 137 3.1E-28 T 12-10-2018 AFR_01555 feaaad084b1ccd81f6f9b77dce4d522c 140 SUPERFAMILY SSF55729 5 135 2.83E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_01555 feaaad084b1ccd81f6f9b77dce4d522c 140 Pfam PF00583 Acetyltransferase (GNAT) family 28 127 5.0E-16 T 12-10-2018 IPR000182 GNAT domain AFR_40140 bced1d9fe56d5014e33c73e2ada99b3f 178 Gene3D G3DSA:1.20.90.10 37 158 1.1E-42 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFR_40140 bced1d9fe56d5014e33c73e2ada99b3f 178 SUPERFAMILY SSF48619 39 158 3.19E-33 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFR_40140 bced1d9fe56d5014e33c73e2ada99b3f 178 Pfam PF09056 Prokaryotic phospholipase A2 54 158 1.2E-34 T 12-10-2018 IPR015141 Phospholipase A2, prokaryotic/fungal AFR_24465 5de0dc923d5272e7306d8214f35fa89a 163 SMART SM00947 24 163 5.2E-26 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_24465 5de0dc923d5272e7306d8214f35fa89a 163 SUPERFAMILY SSF53056 1 162 1.7E-36 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_24465 5de0dc923d5272e7306d8214f35fa89a 163 Pfam PF00484 Carbonic anhydrase 32 100 2.5E-11 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFR_24465 5de0dc923d5272e7306d8214f35fa89a 163 Gene3D G3DSA:3.40.1050.10 1 163 1.1E-61 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFR_01690 9a87d13745dd6684a2bc0fd6b3c34026 464 Pfam PF00146 NADH dehydrogenase 29 365 4.2E-122 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01690 9a87d13745dd6684a2bc0fd6b3c34026 464 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 22 372 24.099 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_01690 9a87d13745dd6684a2bc0fd6b3c34026 464 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 249 262 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_27855 5ce966f1d8ff32e23908bd50b4996657 462 Gene3D G3DSA:3.40.710.10 6 300 1.2E-69 T 12-10-2018 AFR_27855 5ce966f1d8ff32e23908bd50b4996657 462 Pfam PF00144 Beta-lactamase 22 293 1.4E-37 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_27855 5ce966f1d8ff32e23908bd50b4996657 462 SUPERFAMILY SSF56601 3 298 5.36E-72 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 Gene3D G3DSA:3.80.10.10 217 362 1.6E-17 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 Gene3D G3DSA:3.80.10.10 53 216 7.4E-30 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SUPERFAMILY SSF52047 57 344 3.58E-39 T 12-10-2018 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 Pfam PF13516 Leucine Rich repeat 133 155 0.58 T 12-10-2018 IPR001611 Leucine-rich repeat GO:0005515 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 Pfam PF13516 Leucine Rich repeat 309 327 1.3 T 12-10-2018 IPR001611 Leucine-rich repeat GO:0005515 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 Pfam PF13516 Leucine Rich repeat 108 127 0.057 T 12-10-2018 IPR001611 Leucine-rich repeat GO:0005515 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SMART SM00368 306 333 2.5 T 12-10-2018 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SMART SM00368 161 188 7.4 T 12-10-2018 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SMART SM00368 77 104 5.4 T 12-10-2018 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SMART SM00368 190 217 0.073 T 12-10-2018 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SMART SM00368 133 160 0.035 T 12-10-2018 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SMART SM00368 218 244 210.0 T 12-10-2018 AFR_19015 517c6ea7406f9c886875b8d6873ea021 380 SMART SM00368 105 132 5.4 T 12-10-2018 AFR_39865 e3810423e0549d17722f1f4fcefec342 253 Pfam PF00149 Calcineurin-like phosphoesterase 5 185 3.9E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_39865 e3810423e0549d17722f1f4fcefec342 253 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 3 244 34.123 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 AFR_39865 e3810423e0549d17722f1f4fcefec342 253 Gene3D G3DSA:3.60.21.40 5 229 8.6E-67 T 12-10-2018 AFR_39865 e3810423e0549d17722f1f4fcefec342 253 Gene3D G3DSA:3.30.750.180 94 220 8.6E-67 T 12-10-2018 AFR_39865 e3810423e0549d17722f1f4fcefec342 253 SUPERFAMILY SSF56300 5 242 2.13E-49 T 12-10-2018 AFR_18815 ee65b03b2d04f41f460d8449689b3708 94 SUPERFAMILY SSF46785 4 85 7.03E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_18815 ee65b03b2d04f41f460d8449689b3708 94 SMART SM00418 7 85 6.8E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_18815 ee65b03b2d04f41f460d8449689b3708 94 Gene3D G3DSA:1.10.10.10 2 91 6.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_18815 ee65b03b2d04f41f460d8449689b3708 94 Pfam PF01022 Bacterial regulatory protein, arsR family 16 58 1.4E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_18815 ee65b03b2d04f41f460d8449689b3708 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 5.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_18815 ee65b03b2d04f41f460d8449689b3708 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 5.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_18815 ee65b03b2d04f41f460d8449689b3708 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 9 24 5.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 431 1.2E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 SUPERFAMILY SSF47384 208 290 3.53E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 SMART SM00387 325 434 3.1E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 SUPERFAMILY SSF158472 172 219 1.57E-5 T 12-10-2018 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 SMART SM00388 225 291 1.6E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 SUPERFAMILY SSF55874 280 431 1.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 374 1.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 431 1.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 388 1.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 412 1.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 Gene3D G3DSA:1.10.287.130 175 290 7.8E-26 T 12-10-2018 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 Pfam PF00672 HAMP domain 171 219 3.6E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 SMART SM00304 171 224 7.0E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 291 4.6E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFR_25485 7cc831f0ca6c3496249fb9cc9d80d4a3 438 Gene3D G3DSA:3.30.565.10 300 432 7.3E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_07135 3ea7d51fecb36356c6e8b8296cf7d4cd 578 SUPERFAMILY SSF103473 25 540 6.67E-70 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_07135 3ea7d51fecb36356c6e8b8296cf7d4cd 578 Gene3D G3DSA:1.20.1720.10 35 242 2.0E-50 T 12-10-2018 AFR_07135 3ea7d51fecb36356c6e8b8296cf7d4cd 578 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 34 535 1.6E-84 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFR_07135 3ea7d51fecb36356c6e8b8296cf7d4cd 578 Pfam PF07690 Major Facilitator Superfamily 39 437 7.1E-53 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_37565 7ff41265e97be94b8b62d61e333c553e 493 Gene3D G3DSA:1.10.275.10 1 195 1.1E-47 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFR_37565 7ff41265e97be94b8b62d61e333c553e 493 Gene3D G3DSA:1.20.200.10 196 490 1.1E-78 T 12-10-2018 AFR_37565 7ff41265e97be94b8b62d61e333c553e 493 Pfam PF00221 Aromatic amino acid lyase 15 463 1.4E-124 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 AFR_37565 7ff41265e97be94b8b62d61e333c553e 493 SUPERFAMILY SSF48557 21 491 7.85E-133 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFR_11240 08101bfe05e35966472a3fa600b02fa1 621 Gene3D G3DSA:3.40.50.300 164 315 1.7E-10 T 12-10-2018 AFR_11240 08101bfe05e35966472a3fa600b02fa1 621 SMART SM00382 198 337 6.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_11240 08101bfe05e35966472a3fa600b02fa1 621 SUPERFAMILY SSF52540 168 383 2.0E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42050 07997a73e3d48a6d7e3fe8f3392bbaa7 530 Gene3D G3DSA:1.25.40.10 47 353 1.6E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_42050 07997a73e3d48a6d7e3fe8f3392bbaa7 530 Gene3D G3DSA:3.30.70.270 354 525 1.1E-44 T 12-10-2018 AFR_42050 07997a73e3d48a6d7e3fe8f3392bbaa7 530 Pfam PF00990 Diguanylate cyclase, GGDEF domain 352 509 6.6E-34 T 12-10-2018 IPR000160 GGDEF domain AFR_42050 07997a73e3d48a6d7e3fe8f3392bbaa7 530 SMART SM00267 341 513 2.7E-43 T 12-10-2018 IPR000160 GGDEF domain AFR_42050 07997a73e3d48a6d7e3fe8f3392bbaa7 530 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 350 511 2.0E-37 T 12-10-2018 IPR000160 GGDEF domain AFR_42050 07997a73e3d48a6d7e3fe8f3392bbaa7 530 SUPERFAMILY SSF48452 51 199 1.58E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_42050 07997a73e3d48a6d7e3fe8f3392bbaa7 530 SUPERFAMILY SSF55073 357 511 1.02E-37 T 12-10-2018 IPR029787 Nucleotide cyclase AFR_05665 bb8b065e52a9fb38f440b0073acfe8e2 85 Pfam PF02467 Transcription factor WhiB 17 80 4.1E-27 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain AFR_05665 bb8b065e52a9fb38f440b0073acfe8e2 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 85 19.073 T 12-10-2018 IPR003482 Transcription factor WhiB AFR_13950 8e540892555197baa575a384d48b6899 204 SUPERFAMILY SSF46689 8 71 1.95E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13950 8e540892555197baa575a384d48b6899 204 Gene3D G3DSA:1.10.357.10 68 203 2.7E-33 T 12-10-2018 AFR_13950 8e540892555197baa575a384d48b6899 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13950 8e540892555197baa575a384d48b6899 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13950 8e540892555197baa575a384d48b6899 204 Gene3D G3DSA:1.10.10.60 7 63 5.0E-19 T 12-10-2018 AFR_13950 8e540892555197baa575a384d48b6899 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.9E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13950 8e540892555197baa575a384d48b6899 204 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 148 202 3.7E-18 T 12-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type AFR_13950 8e540892555197baa575a384d48b6899 204 SUPERFAMILY SSF48498 82 197 4.32E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_15365 114e97f2b3576b6ef5f44289592d64b6 187 Pfam PF01814 Hemerythrin HHE cation binding domain 9 126 1.0E-15 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFR_15365 114e97f2b3576b6ef5f44289592d64b6 187 Gene3D G3DSA:1.20.120.520 29 147 3.5E-11 T 12-10-2018 AFR_21080 8373e1aa579d6b34e26179197b2d786d 126 Gene3D G3DSA:2.40.50.100 1 125 6.3E-48 T 12-10-2018 AFR_21080 8373e1aa579d6b34e26179197b2d786d 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 2 124 2.1E-48 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFR_21080 8373e1aa579d6b34e26179197b2d786d 126 Pfam PF01597 Glycine cleavage H-protein 6 123 1.9E-42 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate AFR_21080 8373e1aa579d6b34e26179197b2d786d 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 3 125 37.838 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFR_21080 8373e1aa579d6b34e26179197b2d786d 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFR_21080 8373e1aa579d6b34e26179197b2d786d 126 SUPERFAMILY SSF51230 2 125 6.02E-42 T 12-10-2018 IPR011053 Single hybrid motif AFR_06290 06a616064ab87a9cf389c6f6f8235107 204 Gene3D G3DSA:1.10.357.10 1 203 1.6E-42 T 12-10-2018 AFR_06290 06a616064ab87a9cf389c6f6f8235107 204 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 40 198 4.2E-13 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_06290 06a616064ab87a9cf389c6f6f8235107 204 SUPERFAMILY SSF48498 45 202 2.33E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_01865 fcd5a69de6817b109bdaa3128a009ef1 127 Pfam PF07811 TadE-like protein 18 59 9.6E-5 T 12-10-2018 IPR012495 TadE-like AFR_14895 27e41de921e93248248970271e9d43a5 419 Gene3D G3DSA:2.60.40.290 313 419 7.3E-34 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_14895 27e41de921e93248248970271e9d43a5 419 SUPERFAMILY SSF49384 311 417 2.16E-30 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_14895 27e41de921e93248248970271e9d43a5 419 Pfam PF00553 Cellulose binding domain 321 416 5.0E-28 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14895 27e41de921e93248248970271e9d43a5 419 Gene3D G3DSA:3.40.50.1820 46 284 1.6E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14895 27e41de921e93248248970271e9d43a5 419 SMART SM00637 317 416 4.2E-42 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_14895 27e41de921e93248248970271e9d43a5 419 SUPERFAMILY SSF53474 41 271 1.88E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18270 5ddd6e2d4f10500baf064c7b77f02b86 382 Pfam PF01757 Acyltransferase family 6 361 1.7E-25 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_12285 092c04e58d05717430b113f17d57dcf6 320 Gene3D G3DSA:3.30.565.10 190 314 1.7E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12285 092c04e58d05717430b113f17d57dcf6 320 SUPERFAMILY SSF55874 196 313 9.19E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_12285 092c04e58d05717430b113f17d57dcf6 320 Pfam PF07730 Histidine kinase 112 177 2.2E-18 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_26240 eedfb79b40361cae5f56d37d358059b5 324 Pfam PF13672 Protein phosphatase 2C 88 287 4.7E-15 T 12-10-2018 AFR_26240 eedfb79b40361cae5f56d37d358059b5 324 Pfam PF12773 Double zinc ribbon 7 59 1.1E-6 T 12-10-2018 IPR025874 Double zinc ribbon AFR_26240 eedfb79b40361cae5f56d37d358059b5 324 SMART SM00331 81 319 3.9E-4 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_26240 eedfb79b40361cae5f56d37d358059b5 324 Gene3D G3DSA:3.60.40.10 73 321 1.2E-46 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_26240 eedfb79b40361cae5f56d37d358059b5 324 SMART SM00332 72 317 1.8E-11 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_26240 eedfb79b40361cae5f56d37d358059b5 324 SUPERFAMILY SSF81606 78 319 1.44E-36 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_05960 42334c98e88caaf63917a73adecd1efe 205 Pfam PF04350 Pilus assembly protein, PilO 41 188 4.7E-8 T 12-10-2018 IPR007445 Pilus assembly protein, PilO AFR_05960 42334c98e88caaf63917a73adecd1efe 205 Gene3D G3DSA:3.30.70.60 82 197 4.0E-5 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 6.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 6.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 6.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 SMART SM00448 3 118 3.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 SUPERFAMILY SSF52172 3 186 5.29E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 Pfam PF00072 Response regulator receiver domain 5 119 3.7E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 Gene3D G3DSA:3.40.50.12740 3 217 1.7E-68 T 12-10-2018 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 1.3E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_26015 6a0a735b38b612e79e2a133803b3f2c6 226 SMART SM00421 154 211 5.0E-27 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_33625 fa1364bc9755be96b634c4f8e630f1f6 405 Pfam PF04055 Radical SAM superfamily 40 161 2.8E-8 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFR_33625 fa1364bc9755be96b634c4f8e630f1f6 405 TIGRFAM TIGR04269 SAM_SPASM_FxsB: radical SAM/SPASM domain protein, FxsB family 32 393 5.3E-140 T 12-10-2018 IPR026335 Radical SAM/SPASM domain, FxsB family AFR_33625 fa1364bc9755be96b634c4f8e630f1f6 405 SUPERFAMILY SSF102114 29 363 2.62E-25 T 12-10-2018 AFR_33625 fa1364bc9755be96b634c4f8e630f1f6 405 Gene3D G3DSA:3.20.20.70 30 401 9.7E-69 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_33625 fa1364bc9755be96b634c4f8e630f1f6 405 Pfam PF13394 4Fe-4S single cluster domain 41 135 2.3E-5 T 12-10-2018 AFR_40025 ce1b33bb3239d67c54dbc7234ebda58a 305 SUPERFAMILY SSF103481 184 284 1.57E-14 T 12-10-2018 AFR_40025 ce1b33bb3239d67c54dbc7234ebda58a 305 Pfam PF00892 EamA-like transporter family 146 279 2.3E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_40025 ce1b33bb3239d67c54dbc7234ebda58a 305 Pfam PF00892 EamA-like transporter family 10 131 1.6E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_40025 ce1b33bb3239d67c54dbc7234ebda58a 305 SUPERFAMILY SSF103481 34 132 7.06E-8 T 12-10-2018 AFR_20110 25dbe5cc82b4cd5840848f31ed9d7d39 210 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 181 3.6E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_20110 25dbe5cc82b4cd5840848f31ed9d7d39 210 SUPERFAMILY SSF56784 6 189 3.22E-26 T 12-10-2018 IPR036412 HAD-like superfamily AFR_20110 25dbe5cc82b4cd5840848f31ed9d7d39 210 Gene3D G3DSA:3.40.50.1000 5 196 8.1E-27 T 12-10-2018 IPR023214 HAD superfamily AFR_20110 25dbe5cc82b4cd5840848f31ed9d7d39 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 83 180 1.9E-8 T 12-10-2018 AFR_20110 25dbe5cc82b4cd5840848f31ed9d7d39 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 126 142 6.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_20110 25dbe5cc82b4cd5840848f31ed9d7d39 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 6.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_20110 25dbe5cc82b4cd5840848f31ed9d7d39 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 164 6.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFR_16600 3612a3bb7f0fab6e027471dc62b311b3 307 SUPERFAMILY SSF53756 192 301 1.88E-14 T 12-10-2018 AFR_16600 3612a3bb7f0fab6e027471dc62b311b3 307 Pfam PF00534 Glycosyl transferases group 1 197 282 4.6E-9 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_16600 3612a3bb7f0fab6e027471dc62b311b3 307 Gene3D G3DSA:3.40.50.2000 182 288 5.0E-13 T 12-10-2018 AFR_17410 18fe46f8527359fdb392638f53e977d7 832 SUPERFAMILY SSF48452 18 116 1.39E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_17410 18fe46f8527359fdb392638f53e977d7 832 SUPERFAMILY SSF48452 87 354 2.05E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_17410 18fe46f8527359fdb392638f53e977d7 832 Pfam PF13424 Tetratricopeptide repeat 128 191 2.2E-7 T 12-10-2018 AFR_17410 18fe46f8527359fdb392638f53e977d7 832 Pfam PF12770 CHAT domain 590 830 4.6E-27 T 12-10-2018 IPR024983 CHAT domain AFR_17410 18fe46f8527359fdb392638f53e977d7 832 Gene3D G3DSA:1.25.40.10 6 233 7.7E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_05050 f197f4979bd364d57f6d66a8b485fcde 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 328 6.6E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_05050 f197f4979bd364d57f6d66a8b485fcde 338 Pfam PF00005 ABC transporter 37 188 2.2E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_05050 f197f4979bd364d57f6d66a8b485fcde 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 307 1.9E-16 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFR_05050 f197f4979bd364d57f6d66a8b485fcde 338 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_05050 f197f4979bd364d57f6d66a8b485fcde 338 SMART SM00382 45 238 1.0E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_05050 f197f4979bd364d57f6d66a8b485fcde 338 Gene3D G3DSA:3.40.50.300 7 337 7.5E-102 T 12-10-2018 AFR_05050 f197f4979bd364d57f6d66a8b485fcde 338 SUPERFAMILY SSF52540 9 260 1.55E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_39310 865af2d61899ae44c4a829d87f8e80b4 204 Pfam PF03703 Bacterial PH domain 78 152 5.2E-18 T 12-10-2018 IPR005182 Domain of unknown function DUF304 AFR_40510 aba3a4f551c0736c3c95edc765301f3c 144 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 12 77 4.2E-17 T 12-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 AFR_40510 aba3a4f551c0736c3c95edc765301f3c 144 Pfam PF04347 Flagellar biosynthesis protein, FliO 26 91 2.3E-11 T 12-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 AFR_26415 dc089da18df51921e0d631f87c831911 505 PIRSF PIRSF018077 10 502 5.6E-205 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 AFR_26415 dc089da18df51921e0d631f87c831911 505 Pfam PF03136 Pup-ligase protein 5 460 1.9E-190 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 AFR_26415 dc089da18df51921e0d631f87c831911 505 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 4 492 5.0E-227 T 12-10-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 AFR_31950 902b2e8a8a7c47f7bef0748ede0437d2 361 Gene3D G3DSA:1.10.3720.10 92 299 1.9E-14 T 12-10-2018 IPR035906 MetI-like superfamily AFR_31950 902b2e8a8a7c47f7bef0748ede0437d2 361 SUPERFAMILY SSF161098 109 283 2.88E-18 T 12-10-2018 IPR035906 MetI-like superfamily AFR_31950 902b2e8a8a7c47f7bef0748ede0437d2 361 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 305 2.5E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_31950 902b2e8a8a7c47f7bef0748ede0437d2 361 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 34 77 4.1E-8 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFR_14740 b0fdb3e1850f56cf679b12245e18dbe6 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 4.0E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_14740 b0fdb3e1850f56cf679b12245e18dbe6 289 SUPERFAMILY SSF46785 5 98 1.78E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_14740 b0fdb3e1850f56cf679b12245e18dbe6 289 Gene3D G3DSA:1.10.10.10 4 87 2.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26855 a3101bbba685d7f5a2dc28fc9719146a 195 Gene3D G3DSA:3.40.630.30 31 191 5.1E-37 T 12-10-2018 AFR_26855 a3101bbba685d7f5a2dc28fc9719146a 195 Pfam PF13302 Acetyltransferase (GNAT) domain 35 167 7.9E-25 T 12-10-2018 IPR000182 GNAT domain AFR_26855 a3101bbba685d7f5a2dc28fc9719146a 195 SUPERFAMILY SSF55729 31 191 7.39E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_25795 c2cca0e81180deb29bf56c3132a29351 532 Pfam PF01274 Malate synthase 7 516 2.9E-175 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_25795 c2cca0e81180deb29bf56c3132a29351 532 ProSitePatterns PS00510 Malate synthase signature. 255 270 - T 12-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_25795 c2cca0e81180deb29bf56c3132a29351 532 Gene3D G3DSA:3.20.20.360 1 396 1.3E-178 T 12-10-2018 AFR_25795 c2cca0e81180deb29bf56c3132a29351 532 Gene3D G3DSA:1.20.1220.12 401 519 7.8E-35 T 12-10-2018 AFR_25795 c2cca0e81180deb29bf56c3132a29351 532 SUPERFAMILY SSF51645 6 519 5.23E-171 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_25795 c2cca0e81180deb29bf56c3132a29351 532 PIRSF PIRSF001363 1 521 2.2E-221 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_25795 c2cca0e81180deb29bf56c3132a29351 532 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 14 516 5.9E-220 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFR_32340 9ae8c9dad84459738ecb700a407dac14 331 SUPERFAMILY SSF56112 83 317 5.05E-14 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_32340 9ae8c9dad84459738ecb700a407dac14 331 Gene3D G3DSA:1.10.510.10 162 319 3.6E-11 T 12-10-2018 AFR_02245 88c60dcc5c02a52c85db8c00d941a47f 686 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 307 329 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_02245 88c60dcc5c02a52c85db8c00d941a47f 686 Gene3D G3DSA:1.20.120.1760 233 395 6.9E-31 T 12-10-2018 AFR_02245 88c60dcc5c02a52c85db8c00d941a47f 686 Pfam PF01066 CDP-alcohol phosphatidyltransferase 264 329 6.4E-7 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_21380 1ee48fc7258fc9b62c3d60b128e6c22a 438 Gene3D G3DSA:3.40.50.300 1 162 1.7E-5 T 12-10-2018 AFR_26290 b54cfb8ca1fd2685985e0ccfbc75387e 154 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 152 3.7E-19 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_26290 b54cfb8ca1fd2685985e0ccfbc75387e 154 Gene3D G3DSA:3.30.530.20 2 154 9.3E-34 T 12-10-2018 IPR023393 START-like domain superfamily AFR_26290 b54cfb8ca1fd2685985e0ccfbc75387e 154 SUPERFAMILY SSF55961 4 153 2.12E-28 T 12-10-2018 AFR_30490 f8532c59249802663b8459640108221f 282 Gene3D G3DSA:1.10.3720.10 62 278 4.1E-39 T 12-10-2018 IPR035906 MetI-like superfamily AFR_30490 f8532c59249802663b8459640108221f 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 270 2.0E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30490 f8532c59249802663b8459640108221f 282 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 68 170 1.6E-15 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFR_30490 f8532c59249802663b8459640108221f 282 SUPERFAMILY SSF161098 69 260 1.57E-30 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 Pfam PF04542 Sigma-70 region 2 27 91 2.5E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 48 79 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 Gene3D G3DSA:2.80.10.50 406 546 3.3E-35 T 12-10-2018 AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 Gene3D G3DSA:1.10.1740.10 2 114 2.8E-21 T 12-10-2018 AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 185 1.6E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 413 541 3.9E-35 T 12-10-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 SUPERFAMILY SSF110221 411 544 3.01E-30 T 12-10-2018 IPR036195 Alpha-L-arabinofuranosidase B, arabinose-binding domain superfamily GO:0046373|GO:0046556 AFR_14915 a7424468117a3daa7feb46ed66531fb0 547 SUPERFAMILY SSF88946 4 105 6.28E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_15420 06d19e2fe736eda4cdfcd9bd3ef7f8cf 175 Gene3D G3DSA:3.30.505.20 107 175 6.2E-18 T 12-10-2018 AFR_15420 06d19e2fe736eda4cdfcd9bd3ef7f8cf 175 Gene3D G3DSA:3.30.505.20 29 106 1.5E-22 T 12-10-2018 AFR_02845 58a473b3b054029a04897e599781788e 347 Pfam PF14016 Protein of unknown function (DUF4232) 100 196 4.8E-7 T 12-10-2018 IPR025326 Protein of unknown function DUF4232 AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 Pfam PF01047 MarR family 47 102 8.3E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 SMART SM00347 38 138 9.2E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 SUPERFAMILY SSF46785 19 148 6.29E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 Gene3D G3DSA:1.10.10.10 10 150 6.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 2.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 2.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 2.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_11805 e487cf7a48b0d55e484d21bbc959d162 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 2.4E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_18890 ea231aa0dee9455ca6248377f4d8577c 406 Gene3D G3DSA:1.20.1250.20 219 405 2.2E-14 T 12-10-2018 AFR_18890 ea231aa0dee9455ca6248377f4d8577c 406 Pfam PF07690 Major Facilitator Superfamily 264 402 3.6E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_18890 ea231aa0dee9455ca6248377f4d8577c 406 Pfam PF07690 Major Facilitator Superfamily 30 263 1.7E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_18890 ea231aa0dee9455ca6248377f4d8577c 406 SUPERFAMILY SSF103473 23 404 1.7E-43 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_18890 ea231aa0dee9455ca6248377f4d8577c 406 Gene3D G3DSA:1.20.1250.20 22 209 1.7E-21 T 12-10-2018 AFR_13045 3c1be9aacbef47d9a97c277e7b483f58 272 SUPERFAMILY SSF53474 5 260 4.35E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13045 3c1be9aacbef47d9a97c277e7b483f58 272 Pfam PF12697 Alpha/beta hydrolase family 23 253 6.0E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13045 3c1be9aacbef47d9a97c277e7b483f58 272 Gene3D G3DSA:3.40.50.1820 1 265 1.6E-68 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13045 3c1be9aacbef47d9a97c277e7b483f58 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 2.0E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13045 3c1be9aacbef47d9a97c277e7b483f58 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.0E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13045 3c1be9aacbef47d9a97c277e7b483f58 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 2.0E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_13045 3c1be9aacbef47d9a97c277e7b483f58 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.0E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_12025 08b70f42cf953ee53a23667603562725 180 Pfam PF08447 PAS fold 32 113 4.6E-9 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 AFR_12025 08b70f42cf953ee53a23667603562725 180 Gene3D G3DSA:3.30.450.20 16 130 3.1E-20 T 12-10-2018 AFR_12025 08b70f42cf953ee53a23667603562725 180 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 25 110 1.0E-8 T 12-10-2018 IPR000014 PAS domain AFR_12025 08b70f42cf953ee53a23667603562725 180 SUPERFAMILY SSF55785 21 116 4.54E-23 T 12-10-2018 IPR035965 PAS domain superfamily AFR_21250 4cce099b419f0ad3993787d713f64d73 591 Pfam PF04183 IucA / IucC family 291 419 8.0E-20 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 AFR_21250 4cce099b419f0ad3993787d713f64d73 591 Pfam PF04183 IucA / IucC family 236 283 6.3E-10 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 AFR_21250 4cce099b419f0ad3993787d713f64d73 591 Pfam PF06276 Ferric iron reductase FhuF-like transporter 429 547 7.5E-21 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain AFR_21250 4cce099b419f0ad3993787d713f64d73 591 Gene3D G3DSA:1.10.510.40 409 555 4.0E-20 T 12-10-2018 AFR_11880 cfe5943e7ecc1d4ca580042a8e87ebe2 90 SUPERFAMILY SSF47413 8 79 1.44E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_11880 cfe5943e7ecc1d4ca580042a8e87ebe2 90 Gene3D G3DSA:1.10.260.40 7 76 2.1E-30 T 12-10-2018 AFR_11880 cfe5943e7ecc1d4ca580042a8e87ebe2 90 Pfam PF13560 Helix-turn-helix domain 16 74 2.3E-8 T 12-10-2018 AFR_11880 cfe5943e7ecc1d4ca580042a8e87ebe2 90 SMART SM00530 20 74 6.2E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_36010 9d7875c8c9afcf742da90a099aeb1f6b 230 Pfam PF01988 VIT family 15 222 8.2E-58 T 12-10-2018 IPR008217 Ccc1 family AFR_06110 1ab2e68c01a79acd9a376f2cdd5c4725 285 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 6 167 4.0E-34 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFR_06110 1ab2e68c01a79acd9a376f2cdd5c4725 285 SMART SM00943 6 170 2.8E-44 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFR_06110 1ab2e68c01a79acd9a376f2cdd5c4725 285 SUPERFAMILY SSF56747 3 165 3.66E-21 T 12-10-2018 AFR_13000 630787da7b402bfe5e7fb876fd22f7f2 448 Gene3D G3DSA:1.20.1250.20 237 431 2.7E-14 T 12-10-2018 AFR_13000 630787da7b402bfe5e7fb876fd22f7f2 448 Gene3D G3DSA:1.20.1250.20 10 214 1.4E-43 T 12-10-2018 AFR_13000 630787da7b402bfe5e7fb876fd22f7f2 448 Pfam PF07690 Major Facilitator Superfamily 25 387 1.6E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_13000 630787da7b402bfe5e7fb876fd22f7f2 448 SUPERFAMILY SSF103473 8 424 6.8E-73 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_10075 f967f29174a6c62245acdfacc495c80c 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_10075 f967f29174a6c62245acdfacc495c80c 308 SUPERFAMILY SSF55120 78 305 1.76E-66 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_10075 f967f29174a6c62245acdfacc495c80c 308 SUPERFAMILY SSF55174 14 104 2.06E-7 T 12-10-2018 AFR_10075 f967f29174a6c62245acdfacc495c80c 308 Gene3D G3DSA:3.10.290.10 3 66 5.0E-9 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFR_10075 f967f29174a6c62245acdfacc495c80c 308 Gene3D G3DSA:3.30.2350.10 81 308 2.6E-67 T 12-10-2018 AFR_10075 f967f29174a6c62245acdfacc495c80c 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 305 4.7E-86 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_10075 f967f29174a6c62245acdfacc495c80c 308 Pfam PF00849 RNA pseudouridylate synthase 89 243 1.6E-32 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFR_35235 979744e00586590a6e2d0e61571c9775 458 Gene3D G3DSA:2.130.10.10 68 410 1.3E-13 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_35235 979744e00586590a6e2d0e61571c9775 458 SUPERFAMILY SSF50998 88 383 2.35E-11 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_42540 6b145c47439de2614275069d29d75520 385 PIRSF PIRSF006356 1 385 8.7E-126 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AFR_42540 6b145c47439de2614275069d29d75520 385 Pfam PF02274 Amidinotransferase 2 382 8.7E-96 T 12-10-2018 AFR_42540 6b145c47439de2614275069d29d75520 385 Gene3D G3DSA:3.75.10.10 1 382 3.2E-132 T 12-10-2018 AFR_42540 6b145c47439de2614275069d29d75520 385 Gene3D G3DSA:1.10.3930.10 52 135 3.2E-132 T 12-10-2018 AFR_42540 6b145c47439de2614275069d29d75520 385 PRINTS PR01466 Bacterial arginine deiminase signature 321 338 3.4E-36 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AFR_42540 6b145c47439de2614275069d29d75520 385 PRINTS PR01466 Bacterial arginine deiminase signature 341 355 3.4E-36 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AFR_42540 6b145c47439de2614275069d29d75520 385 PRINTS PR01466 Bacterial arginine deiminase signature 164 179 3.4E-36 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AFR_42540 6b145c47439de2614275069d29d75520 385 PRINTS PR01466 Bacterial arginine deiminase signature 136 154 3.4E-36 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AFR_42540 6b145c47439de2614275069d29d75520 385 PRINTS PR01466 Bacterial arginine deiminase signature 364 382 3.4E-36 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AFR_42540 6b145c47439de2614275069d29d75520 385 SUPERFAMILY SSF55909 1 384 2.16E-111 T 12-10-2018 AFR_14605 2a59737c8d979076e2f62b130a66dcb0 335 SUPERFAMILY SSF161098 93 321 2.13E-20 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14605 2a59737c8d979076e2f62b130a66dcb0 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 333 2.4E-38 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_14605 2a59737c8d979076e2f62b130a66dcb0 335 Gene3D G3DSA:1.10.3720.10 84 326 1.2E-27 T 12-10-2018 IPR035906 MetI-like superfamily AFR_36955 bdd7e4e6770ca3a2de5670551d3cbf5b 308 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 213 229 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFR_36955 bdd7e4e6770ca3a2de5670551d3cbf5b 308 SUPERFAMILY SSF51735 95 274 6.75E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_36955 bdd7e4e6770ca3a2de5670551d3cbf5b 308 Gene3D G3DSA:3.40.50.720 22 302 7.0E-73 T 12-10-2018 AFR_36955 bdd7e4e6770ca3a2de5670551d3cbf5b 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 273 1.2E-47 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFR_36955 bdd7e4e6770ca3a2de5670551d3cbf5b 308 Gene3D G3DSA:3.40.50.720 94 279 7.0E-73 T 12-10-2018 AFR_31340 3513e84c98f337574f0a9c5b2d03555e 318 PIRSF PIRSF035875 4 314 3.7E-73 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_31340 3513e84c98f337574f0a9c5b2d03555e 318 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 29 290 2.9E-31 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_31340 3513e84c98f337574f0a9c5b2d03555e 318 Pfam PF03631 Virulence factor BrkB 33 292 2.7E-58 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_13800 361422cc0c060e64c9d2312e050e91ea 609 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 103 313 2.7E-11 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AFR_13800 361422cc0c060e64c9d2312e050e91ea 609 Gene3D G3DSA:3.20.20.80 31 342 4.8E-56 T 12-10-2018 AFR_13800 361422cc0c060e64c9d2312e050e91ea 609 Gene3D G3DSA:2.60.120.260 372 475 2.4E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_13800 361422cc0c060e64c9d2312e050e91ea 609 Gene3D G3DSA:2.60.120.260 501 601 1.9E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_13800 361422cc0c060e64c9d2312e050e91ea 609 SUPERFAMILY SSF51445 42 322 8.86E-44 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_39820 984c43253a432983a33e42763b625080 435 Gene3D G3DSA:2.60.40.10 133 226 1.2E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_39820 984c43253a432983a33e42763b625080 435 SUPERFAMILY SSF49299 128 211 2.75E-6 T 12-10-2018 IPR035986 PKD domain superfamily AFR_03360 4e45bc65f5900c943976582eeea44aa3 166 SUPERFAMILY SSF50475 22 152 1.01E-19 T 12-10-2018 AFR_03360 4e45bc65f5900c943976582eeea44aa3 166 Gene3D G3DSA:2.30.110.10 21 164 1.1E-26 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_03360 4e45bc65f5900c943976582eeea44aa3 166 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 107 1.7E-11 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_22890 32cbecb7ad149a6a24edeed08413cbf4 331 Gene3D G3DSA:3.20.20.100 1 328 1.3E-102 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_22890 32cbecb7ad149a6a24edeed08413cbf4 331 SUPERFAMILY SSF51430 3 309 1.44E-87 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_22890 32cbecb7ad149a6a24edeed08413cbf4 331 Pfam PF00248 Aldo/keto reductase family 16 308 2.4E-63 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_27335 60c77fd32fbf982b6e20ef975183033a 228 Pfam PF03932 CutC family 12 202 5.8E-31 T 12-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 AFR_27335 60c77fd32fbf982b6e20ef975183033a 228 Gene3D G3DSA:3.20.20.380 11 228 1.4E-51 T 12-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 AFR_27335 60c77fd32fbf982b6e20ef975183033a 228 SUPERFAMILY SSF110395 11 227 5.23E-45 T 12-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 220 232 3.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 204 220 3.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 204 3.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 Pfam PF00196 Bacterial regulatory proteins, luxR family 189 241 3.3E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 SUPERFAMILY SSF46894 185 250 1.9E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 SMART SM00421 187 244 8.0E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 Gene3D G3DSA:1.10.10.10 181 251 3.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04940 9cf3e52a46f3e76f0f76460572ad1377 251 ProSitePatterns PS00622 LuxR-type HTH domain signature. 204 231 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_12820 448993ed6a727be4f10627ef2effbe1a 150 SUPERFAMILY SSF55961 1 147 1.55E-12 T 12-10-2018 AFR_12820 448993ed6a727be4f10627ef2effbe1a 150 Gene3D G3DSA:3.30.530.20 3 147 3.6E-5 T 12-10-2018 IPR023393 START-like domain superfamily AFR_12820 448993ed6a727be4f10627ef2effbe1a 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 145 3.2E-8 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_07615 2e74c7026d22d1fa9b3d42313e35a291 146 Pfam PF02627 Carboxymuconolactone decarboxylase family 13 91 2.7E-17 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_07615 2e74c7026d22d1fa9b3d42313e35a291 146 Gene3D G3DSA:1.20.1290.10 1 145 2.0E-45 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_07615 2e74c7026d22d1fa9b3d42313e35a291 146 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 27 75 3.8E-16 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_07615 2e74c7026d22d1fa9b3d42313e35a291 146 SUPERFAMILY SSF69118 9 142 1.63E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_28355 6d718f25062f168884c2d07ec43bccbc 118 Gene3D G3DSA:3.30.750.24 1 96 5.5E-18 T 12-10-2018 IPR036513 STAS domain superfamily AFR_28355 6d718f25062f168884c2d07ec43bccbc 118 SUPERFAMILY SSF52091 3 88 8.63E-15 T 12-10-2018 IPR036513 STAS domain superfamily AFR_28355 6d718f25062f168884c2d07ec43bccbc 118 Pfam PF13466 STAS domain 3 79 7.3E-13 T 12-10-2018 IPR002645 STAS domain AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 ProSitePatterns PS00211 ABC transporters family signature. 388 402 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 SUPERFAMILY SSF52540 16 229 1.52E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 SMART SM00382 279 463 2.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 SMART SM00382 30 214 1.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 Pfam PF00005 ABC transporter 22 166 4.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 SUPERFAMILY SSF52540 260 461 2.86E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 Gene3D G3DSA:3.40.50.300 3 237 1.3E-60 T 12-10-2018 AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 Gene3D G3DSA:3.40.50.300 256 463 4.6E-49 T 12-10-2018 AFR_08045 9115f01c3441fc8b015539c45c25c46f 463 Pfam PF00005 ABC transporter 270 415 2.7E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 Pfam PF10369 Small subunit of acetolactate synthase 85 158 8.8E-28 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 2.1E-62 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 Pfam PF13710 ACT domain 13 74 1.5E-17 T 12-10-2018 AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 SUPERFAMILY SSF55021 3 76 8.09E-23 T 12-10-2018 AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 SUPERFAMILY SSF55021 81 162 9.54E-26 T 12-10-2018 AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 Gene3D G3DSA:3.30.70.260 1 79 6.1E-37 T 12-10-2018 AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 Gene3D G3DSA:3.30.70.1150 84 163 3.2E-29 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal AFR_36890 dc1abbe69f3217c9ecacae1858b7bba5 171 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 5.0E-30 T 12-10-2018 AFR_34725 a59f617e177eded1e0e39b00bac14a69 138 Gene3D G3DSA:3.30.420.40 2 101 5.3E-14 T 12-10-2018 AFR_34725 a59f617e177eded1e0e39b00bac14a69 138 SUPERFAMILY SSF53067 8 124 1.19E-15 T 12-10-2018 AFR_12965 866a4e58e368d553393e236321e1a332 361 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 119 2.0E-15 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFR_12965 866a4e58e368d553393e236321e1a332 361 Gene3D G3DSA:3.30.360.10 138 345 9.8E-80 T 12-10-2018 AFR_12965 866a4e58e368d553393e236321e1a332 361 SUPERFAMILY SSF51735 4 173 6.62E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12965 866a4e58e368d553393e236321e1a332 361 SUPERFAMILY SSF55347 132 280 3.14E-16 T 12-10-2018 AFR_12965 866a4e58e368d553393e236321e1a332 361 Gene3D G3DSA:3.40.50.720 6 338 9.8E-80 T 12-10-2018 AFR_41485 8c55c75510a93b9658575476bb1ba6d6 1148 Gene3D G3DSA:1.10.8.730 820 945 1.0E-11 T 12-10-2018 AFR_41485 8c55c75510a93b9658575476bb1ba6d6 1148 Pfam PF12846 AAA-like domain 859 1117 3.7E-21 T 12-10-2018 AFR_41485 8c55c75510a93b9658575476bb1ba6d6 1148 Gene3D G3DSA:3.40.50.300 756 1051 1.0E-11 T 12-10-2018 AFR_41485 8c55c75510a93b9658575476bb1ba6d6 1148 SUPERFAMILY SSF52540 701 1073 1.45E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_00120 d757246742d62bb3e50df3486c1c4733 299 Gene3D G3DSA:3.40.250.10 4 155 8.9E-43 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_00120 d757246742d62bb3e50df3486c1c4733 299 ProSitePatterns PS00683 Rhodanese C-terminal signature. 271 281 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFR_00120 d757246742d62bb3e50df3486c1c4733 299 Gene3D G3DSA:3.40.250.10 156 298 4.3E-42 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_00120 d757246742d62bb3e50df3486c1c4733 299 SMART SM00450 21 135 2.6E-19 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_00120 d757246742d62bb3e50df3486c1c4733 299 SMART SM00450 160 287 4.8E-20 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_00120 d757246742d62bb3e50df3486c1c4733 299 Pfam PF00581 Rhodanese-like domain 167 282 7.4E-18 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_00120 d757246742d62bb3e50df3486c1c4733 299 Pfam PF00581 Rhodanese-like domain 22 131 2.3E-13 T 12-10-2018 IPR001763 Rhodanese-like domain AFR_00120 d757246742d62bb3e50df3486c1c4733 299 ProSitePatterns PS00380 Rhodanese signature 1. 47 58 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFR_00120 d757246742d62bb3e50df3486c1c4733 299 SUPERFAMILY SSF52821 163 292 2.23E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_00120 d757246742d62bb3e50df3486c1c4733 299 SUPERFAMILY SSF52821 14 152 1.31E-36 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFR_42010 94d642587380cbf208965f0794914589 250 Pfam PF01738 Dienelactone hydrolase family 16 245 3.9E-42 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFR_42010 94d642587380cbf208965f0794914589 250 SUPERFAMILY SSF53474 2 247 1.59E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_42010 94d642587380cbf208965f0794914589 250 Gene3D G3DSA:3.40.50.1820 1 245 5.1E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33435 f9da9d864a5fba28d99b81d98389c0b7 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 2.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33435 f9da9d864a5fba28d99b81d98389c0b7 197 SUPERFAMILY SSF46689 3 63 6.16E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_33435 f9da9d864a5fba28d99b81d98389c0b7 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 7.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33435 f9da9d864a5fba28d99b81d98389c0b7 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 7.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_33435 f9da9d864a5fba28d99b81d98389c0b7 197 Gene3D G3DSA:1.10.357.10 1 195 1.4E-20 T 12-10-2018 AFR_29585 8f82aa406c79285a18676c799d97778d 908 Pfam PF08665 PglZ domain 488 658 1.4E-6 T 12-10-2018 IPR013973 PglZ domain AFR_29585 8f82aa406c79285a18676c799d97778d 908 SUPERFAMILY SSF53649 486 659 9.68E-5 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_36635 b2964cb618b02a33acfbbfdd57c3b87c 118 Gene3D G3DSA:1.10.10.10 5 117 2.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36635 b2964cb618b02a33acfbbfdd57c3b87c 118 SUPERFAMILY SSF46785 4 75 2.47E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_36635 b2964cb618b02a33acfbbfdd57c3b87c 118 SMART SM00345 12 71 9.5E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_36635 b2964cb618b02a33acfbbfdd57c3b87c 118 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 2.7E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_14945 2e2be4e4d0fddfbf1615ad74cd6b3761 498 Pfam PF02065 Melibiase 167 337 9.6E-17 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFR_14945 2e2be4e4d0fddfbf1615ad74cd6b3761 498 Gene3D G3DSA:3.20.20.70 161 463 6.6E-89 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_14945 2e2be4e4d0fddfbf1615ad74cd6b3761 498 SUPERFAMILY SSF51445 168 462 7.32E-63 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_30445 7076cbb69a40eb04f5f1a2a6fdcaddca 353 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 349 43.196 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 AFR_30445 7076cbb69a40eb04f5f1a2a6fdcaddca 353 Pfam PF01409 tRNA synthetases class II core domain (F) 109 349 4.1E-95 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AFR_30445 7076cbb69a40eb04f5f1a2a6fdcaddca 353 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 68 349 1.3E-83 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFR_30445 7076cbb69a40eb04f5f1a2a6fdcaddca 353 SUPERFAMILY SSF55681 109 350 1.68E-71 T 12-10-2018 AFR_30445 7076cbb69a40eb04f5f1a2a6fdcaddca 353 SUPERFAMILY SSF46589 31 115 8.89E-14 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFR_30445 7076cbb69a40eb04f5f1a2a6fdcaddca 353 Gene3D G3DSA:3.30.930.10 25 351 3.7E-103 T 12-10-2018 AFR_30445 7076cbb69a40eb04f5f1a2a6fdcaddca 353 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 36 103 3.0E-15 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFR_08390 5a2080224bd39ea83cc9c32737b5cf71 240 SMART SM00342 135 219 0.0061 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_08390 5a2080224bd39ea83cc9c32737b5cf71 240 Pfam PF12833 Helix-turn-helix domain 146 220 2.9E-8 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_08390 5a2080224bd39ea83cc9c32737b5cf71 240 Gene3D G3DSA:1.10.10.60 135 224 3.1E-9 T 12-10-2018 AFR_26685 bc8a8540fcb8380c418b86ffc2052840 200 Gene3D G3DSA:1.20.120.520 16 153 6.9E-10 T 12-10-2018 AFR_26685 bc8a8540fcb8380c418b86ffc2052840 200 Pfam PF01814 Hemerythrin HHE cation binding domain 19 134 1.9E-9 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFR_36290 1215d0010eb55d7f4c9d73b2e6e75e8c 272 Pfam PF01351 Ribonuclease HII 31 209 4.5E-32 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain AFR_36290 1215d0010eb55d7f4c9d73b2e6e75e8c 272 Hamap MF_00052_B Ribonuclease HII [rnhB]. 29 210 33.044 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 AFR_36290 1215d0010eb55d7f4c9d73b2e6e75e8c 272 SUPERFAMILY SSF53098 19 213 8.04E-57 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_36290 1215d0010eb55d7f4c9d73b2e6e75e8c 272 Gene3D G3DSA:3.30.420.10 12 223 1.5E-62 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_08410 fcbbc3ff9192e4c7f72bef94e7b4a6bf 139 Gene3D G3DSA:3.10.180.10 3 137 1.4E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_08410 fcbbc3ff9192e4c7f72bef94e7b4a6bf 139 SUPERFAMILY SSF54593 5 129 3.03E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_08410 fcbbc3ff9192e4c7f72bef94e7b4a6bf 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 127 8.8E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_03130 f0130ce16ec5087b3c65b704463f7472 273 SUPERFAMILY SSF47413 28 80 3.44E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_03130 f0130ce16ec5087b3c65b704463f7472 273 SMART SM00530 9 81 2.3E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_03130 f0130ce16ec5087b3c65b704463f7472 273 Gene3D G3DSA:1.10.260.40 3 81 4.5E-9 T 12-10-2018 AFR_03130 f0130ce16ec5087b3c65b704463f7472 273 Pfam PF13560 Helix-turn-helix domain 5 84 5.1E-19 T 12-10-2018 AFR_29325 eefef7d65eb03083a52efad35c430d22 118 SUPERFAMILY SSF54427 2 108 9.17E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_29325 eefef7d65eb03083a52efad35c430d22 118 Gene3D G3DSA:3.10.450.50 1 104 7.8E-24 T 12-10-2018 AFR_29325 eefef7d65eb03083a52efad35c430d22 118 Pfam PF07366 SnoaL-like polyketide cyclase 4 104 3.7E-14 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 AFR_24635 4004712d51deba511d0b20400f8bdf34 149 SUPERFAMILY SSF54427 3 132 1.1E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_24635 4004712d51deba511d0b20400f8bdf34 149 Pfam PF12680 SnoaL-like domain 10 132 1.7E-11 T 12-10-2018 IPR037401 SnoaL-like domain AFR_24635 4004712d51deba511d0b20400f8bdf34 149 Gene3D G3DSA:3.10.450.50 2 139 8.2E-21 T 12-10-2018 AFR_03395 6b60882443adcda2610304ff7906a747 399 SUPERFAMILY SSF48264 18 398 4.19E-91 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 Pfam PF00067 Cytochrome P450 275 371 5.3E-15 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 Pfam PF00067 Cytochrome P450 88 264 1.2E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 Gene3D G3DSA:1.10.630.10 4 399 3.7E-128 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 135 151 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 350 361 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 91 102 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 292 319 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 341 350 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 152 167 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 275 286 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 320 335 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00359 B-class P450 signature 194 216 2.9E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00385 P450 superfamily signature 341 350 9.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00385 P450 superfamily signature 275 286 9.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00385 P450 superfamily signature 240 257 9.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_03395 6b60882443adcda2610304ff7906a747 399 PRINTS PR00385 P450 superfamily signature 350 361 9.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_16165 e01c3188ff59e043633baa7127769435 579 Gene3D G3DSA:3.20.20.190 11 328 4.0E-96 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_16165 e01c3188ff59e043633baa7127769435 579 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 533 568 2.2E-11 T 12-10-2018 AFR_16165 e01c3188ff59e043633baa7127769435 579 SUPERFAMILY SSF51695 22 321 6.8E-60 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_16165 e01c3188ff59e043633baa7127769435 579 Gene3D G3DSA:3.20.20.190 344 572 1.5E-6 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_16165 e01c3188ff59e043633baa7127769435 579 SUPERFAMILY SSF51695 342 571 1.18E-14 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_16165 e01c3188ff59e043633baa7127769435 579 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 25 315 1.1E-37 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFR_09725 766dc16d3b02564e552ada72f16be884 304 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 26 298 1.0E-94 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 AFR_09725 766dc16d3b02564e552ada72f16be884 304 SUPERFAMILY SSF51730 16 298 1.8E-90 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like AFR_09725 766dc16d3b02564e552ada72f16be884 304 Gene3D G3DSA:3.20.20.220 17 304 3.6E-97 T 12-10-2018 AFR_09725 766dc16d3b02564e552ada72f16be884 304 Pfam PF02219 Methylenetetrahydrofolate reductase 18 298 1.0E-96 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFR_35405 8e6952fd2ec9b94d422092c3852dd020 140 Gene3D G3DSA:3.50.80.10 1 140 4.6E-42 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily AFR_35405 8e6952fd2ec9b94d422092c3852dd020 140 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 139 5.0E-49 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFR_35405 8e6952fd2ec9b94d422092c3852dd020 140 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 139 2.2E-40 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFR_35405 8e6952fd2ec9b94d422092c3852dd020 140 SUPERFAMILY SSF69500 1 140 4.97E-44 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily AFR_35405 8e6952fd2ec9b94d422092c3852dd020 140 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 140 29.01 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFR_04205 eaa0548cec8d681679598d42cbb110e5 483 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 56 345 4.2E-17 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AFR_04205 eaa0548cec8d681679598d42cbb110e5 483 Gene3D G3DSA:3.40.640.10 47 304 6.1E-93 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_04205 eaa0548cec8d681679598d42cbb110e5 483 SUPERFAMILY SSF53383 4 402 6.19E-89 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_04205 eaa0548cec8d681679598d42cbb110e5 483 Gene3D G3DSA:3.90.1150.10 9 386 6.1E-93 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_05055 4bb5611ceff054a29fa75eeb4e7608f2 123 SUPERFAMILY SSF54593 2 120 3.49E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_05055 4bb5611ceff054a29fa75eeb4e7608f2 123 Gene3D G3DSA:3.10.180.10 1 121 5.3E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_05055 4bb5611ceff054a29fa75eeb4e7608f2 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 118 1.1E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_28000 4cbff06c1a5d41873a26390c31ab52ae 74 Pfam PF13459 4Fe-4S single cluster domain 8 61 2.4E-11 T 12-10-2018 AFR_28000 4cbff06c1a5d41873a26390c31ab52ae 74 Gene3D G3DSA:3.30.70.20 3 64 7.1E-16 T 12-10-2018 AFR_28000 4cbff06c1a5d41873a26390c31ab52ae 74 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 1.1E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_28000 4cbff06c1a5d41873a26390c31ab52ae 74 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 1.1E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_28000 4cbff06c1a5d41873a26390c31ab52ae 74 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.1E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_28000 4cbff06c1a5d41873a26390c31ab52ae 74 SUPERFAMILY SSF54862 5 62 4.19E-10 T 12-10-2018 AFR_22370 b9611f6303d20aaa2cfd39c205c1453e 303 Gene3D G3DSA:1.10.3720.10 86 293 3.6E-20 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22370 b9611f6303d20aaa2cfd39c205c1453e 303 SUPERFAMILY SSF161098 90 302 8.76E-17 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22370 b9611f6303d20aaa2cfd39c205c1453e 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 302 1.6E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_37305 a156e2c009c0a2116030a2ddcc5657b5 208 Pfam PF07081 Protein of unknown function (DUF1349) 18 198 1.2E-46 T 12-10-2018 IPR009784 Protein of unknown function DUF1349 AFR_37305 a156e2c009c0a2116030a2ddcc5657b5 208 SUPERFAMILY SSF49899 68 198 3.21E-17 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_37305 a156e2c009c0a2116030a2ddcc5657b5 208 Gene3D G3DSA:2.60.120.200 14 208 8.5E-47 T 12-10-2018 AFR_33950 292554b355f30a806a538f247e414eb4 411 Pfam PF07350 Protein of unknown function (DUF1479) 7 411 4.9E-130 T 12-10-2018 IPR010856 Protein of unknown function DUF1479 AFR_33950 292554b355f30a806a538f247e414eb4 411 SUPERFAMILY SSF51197 4 411 1.83E-137 T 12-10-2018 AFR_33950 292554b355f30a806a538f247e414eb4 411 Gene3D G3DSA:2.60.120.330 1 411 3.3E-141 T 12-10-2018 IPR027443 Isopenicillin N synthase-like AFR_07790 745c03b27bb292ec731e5954c00fc21a 322 SUPERFAMILY SSF56112 24 317 1.04E-20 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_07790 745c03b27bb292ec731e5954c00fc21a 322 Pfam PF01636 Phosphotransferase enzyme family 56 250 3.2E-7 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_07790 745c03b27bb292ec731e5954c00fc21a 322 Gene3D G3DSA:3.30.200.20 24 102 3.2E-5 T 12-10-2018 AFR_09190 e530d77b7165826ceca05d79b0f48846 230 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 61 211 9.0E-33 T 12-10-2018 AFR_09190 e530d77b7165826ceca05d79b0f48846 230 Pfam PF13829 Domain of unknown function (DUF4191) 11 219 9.3E-74 T 12-10-2018 IPR025445 Protein of unknown function DUF4191 AFR_03620 0583eade670b7fa1941b66bbe7be41a3 316 Gene3D G3DSA:3.80.10.10 42 316 3.3E-84 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily AFR_03620 0583eade670b7fa1941b66bbe7be41a3 316 SUPERFAMILY SSF52047 82 287 9.03E-12 T 12-10-2018 AFR_41580 7899321187b020091c8e8b3e60559991 435 SUPERFAMILY SSF52743 65 341 1.57E-75 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_41580 7899321187b020091c8e8b3e60559991 435 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 87 98 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFR_41580 7899321187b020091c8e8b3e60559991 435 Gene3D G3DSA:3.40.50.200 37 347 2.7E-85 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_41580 7899321187b020091c8e8b3e60559991 435 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 72 392 5.3E-96 T 12-10-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin AFR_41580 7899321187b020091c8e8b3e60559991 435 Pfam PF00082 Subtilase family 82 331 2.5E-35 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_41580 7899321187b020091c8e8b3e60559991 435 PRINTS PR00723 Subtilisin serine protease family (S8) signature 280 296 8.6E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41580 7899321187b020091c8e8b3e60559991 435 PRINTS PR00723 Subtilisin serine protease family (S8) signature 121 134 8.6E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41580 7899321187b020091c8e8b3e60559991 435 PRINTS PR00723 Subtilisin serine protease family (S8) signature 82 101 8.6E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_41580 7899321187b020091c8e8b3e60559991 435 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 281 291 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFR_14205 45f69067f8beb3a2b490eaa60759e4f1 292 SUPERFAMILY SSF53474 6 289 4.4E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14205 45f69067f8beb3a2b490eaa60759e4f1 292 Gene3D G3DSA:3.40.50.1820 2 291 2.4E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14205 45f69067f8beb3a2b490eaa60759e4f1 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 7.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_14205 45f69067f8beb3a2b490eaa60759e4f1 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 7.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_14205 45f69067f8beb3a2b490eaa60759e4f1 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 237 251 7.2E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_14205 45f69067f8beb3a2b490eaa60759e4f1 292 Pfam PF00561 alpha/beta hydrolase fold 23 274 1.7E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_39590 76820e7e46552e53c0e66529c9216d75 317 Gene3D G3DSA:3.40.50.2300 102 307 2.6E-81 T 12-10-2018 AFR_39590 76820e7e46552e53c0e66529c9216d75 317 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 1 288 9.9E-49 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 AFR_39590 76820e7e46552e53c0e66529c9216d75 317 Gene3D G3DSA:3.40.50.2300 6 280 2.6E-81 T 12-10-2018 AFR_39590 76820e7e46552e53c0e66529c9216d75 317 SUPERFAMILY SSF53822 12 252 1.14E-6 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_34390 4d0938143a306cd1007ec211c39f0657 378 SUPERFAMILY SSF56601 4 377 2.82E-80 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_34390 4d0938143a306cd1007ec211c39f0657 378 Gene3D G3DSA:3.40.710.10 2 377 4.5E-91 T 12-10-2018 AFR_34390 4d0938143a306cd1007ec211c39f0657 378 Pfam PF00144 Beta-lactamase 7 363 9.1E-60 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 Gene3D G3DSA:1.10.630.10 20 401 7.0E-117 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 Pfam PF00067 Cytochrome P450 185 372 3.2E-26 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 274 285 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 350 361 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 139 155 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 292 319 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 193 215 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 156 171 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 92 103 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 320 335 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00359 B-class P450 signature 341 350 4.6E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00385 P450 superfamily signature 239 256 7.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00385 P450 superfamily signature 341 350 7.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00385 P450 superfamily signature 350 361 7.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 PRINTS PR00385 P450 superfamily signature 274 285 7.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_21335 47d50db36e8a39509df4b95a1c77a2c7 401 SUPERFAMILY SSF48264 26 401 7.2E-94 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_14210 b9f42fc4f2beaac47270ead278291b34 217 Gene3D G3DSA:1.10.357.10 82 217 5.6E-19 T 12-10-2018 AFR_14210 b9f42fc4f2beaac47270ead278291b34 217 Gene3D G3DSA:1.10.10.60 1 76 2.2E-26 T 12-10-2018 AFR_14210 b9f42fc4f2beaac47270ead278291b34 217 SUPERFAMILY SSF46689 16 78 1.26E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_14210 b9f42fc4f2beaac47270ead278291b34 217 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 82 214 2.9E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_14210 b9f42fc4f2beaac47270ead278291b34 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 70 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_14210 b9f42fc4f2beaac47270ead278291b34 217 SUPERFAMILY SSF48498 87 214 2.11E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_42395 cc97ca1b5ddc698a94b5d67ebaa8a3ba 243 Gene3D G3DSA:3.90.550.10 1 242 3.5E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_42395 cc97ca1b5ddc698a94b5d67ebaa8a3ba 243 SUPERFAMILY SSF53448 1 238 2.82E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_42395 cc97ca1b5ddc698a94b5d67ebaa8a3ba 243 Pfam PF00483 Nucleotidyl transferase 3 112 5.5E-12 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFR_32205 7e393aec664eb034545bf28de974cee8 954 Pfam PF04434 SWIM zinc finger 67 86 5.3E-5 T 12-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 SUPERFAMILY SSF54211 3 195 3.72E-55 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00473 Galactokinase signature 24 42 2.6E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00473 Galactokinase signature 260 274 2.6E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00473 Galactokinase signature 85 96 2.6E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00473 Galactokinase signature 105 123 2.6E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 ProSitePatterns PS00106 Galactokinase signature. 24 35 - T 12-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 Pfam PF00288 GHMP kinases N terminal domain 107 172 1.5E-14 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00959 Mevalonate kinase family signature 112 134 1.5E-39 T 12-10-2018 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00959 Mevalonate kinase family signature 22 46 1.5E-39 T 12-10-2018 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00959 Mevalonate kinase family signature 155 174 1.5E-39 T 12-10-2018 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PRINTS PR00959 Mevalonate kinase family signature 323 340 1.5E-39 T 12-10-2018 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 Pfam PF08544 GHMP kinases C terminal 276 355 8.5E-15 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 Hamap MF_00246 Galactokinase [galK]. 22 376 39.237 T 12-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 Gene3D G3DSA:3.30.70.890 195 352 4.6E-127 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 PIRSF PIRSF000530 1 378 1.0E-112 T 12-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 TIGRFAM TIGR00131 gal_kin: galactokinase 4 373 1.9E-94 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 Gene3D G3DSA:3.30.230.10 20 194 4.6E-127 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 Pfam PF10509 Galactokinase galactose-binding signature 7 54 9.7E-22 T 12-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFR_39635 81d20ab162317b27d0b6b31f56ea7d4e 378 SUPERFAMILY SSF55060 200 376 1.44E-52 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFR_22535 78b760e0ba68b9568e7e4d79b537564e 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 303 7.2E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_22535 78b760e0ba68b9568e7e4d79b537564e 314 Gene3D G3DSA:1.10.3720.10 72 313 4.6E-72 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22535 78b760e0ba68b9568e7e4d79b537564e 314 SUPERFAMILY SSF161098 74 299 3.01E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_00400 0a028cd2911dc68b45f9cb604994e334 93 Pfam PF03795 YCII-related domain 12 77 1.8E-10 T 12-10-2018 IPR005545 YCII-related AFR_00400 0a028cd2911dc68b45f9cb604994e334 93 Gene3D G3DSA:3.30.70.1060 2 82 5.6E-8 T 12-10-2018 AFR_00400 0a028cd2911dc68b45f9cb604994e334 93 SUPERFAMILY SSF54909 2 84 3.22E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_37220 6f0a300a15c3195288f6a9449a53d2db 432 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 18 44 4.2E-7 T 12-10-2018 IPR019933 DivIVA domain AFR_40835 459f8dccda2d7fbd950c2ccea68fe435 248 Gene3D G3DSA:3.40.50.150 1 248 1.3E-83 T 12-10-2018 AFR_40835 459f8dccda2d7fbd950c2ccea68fe435 248 SUPERFAMILY SSF53335 5 247 4.94E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_40835 459f8dccda2d7fbd950c2ccea68fe435 248 Pfam PF13649 Methyltransferase domain 41 134 2.3E-8 T 12-10-2018 AFR_28120 c894c4ff58a60295b8cce94cbf9c3770 822 Gene3D G3DSA:3.30.565.10 499 644 3.5E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28120 c894c4ff58a60295b8cce94cbf9c3770 822 SMART SM00387 536 646 0.0042 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_28120 c894c4ff58a60295b8cce94cbf9c3770 822 Pfam PF08376 Nitrate and nitrite sensing 86 315 5.3E-39 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein AFR_28120 c894c4ff58a60295b8cce94cbf9c3770 822 SUPERFAMILY SSF55874 516 647 2.1E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28120 c894c4ff58a60295b8cce94cbf9c3770 822 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 539 644 1.0E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_20450 c057734bcbeb15322e9961d277294fa8 541 Gene3D G3DSA:3.40.50.10490 96 289 6.7E-223 T 12-10-2018 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 Gene3D G3DSA:3.40.50.10490 11 496 6.7E-223 T 12-10-2018 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 Gene3D G3DSA:1.10.1390.10 497 539 4.5E-17 T 12-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 487 504 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 Pfam PF00342 Phosphoglucose isomerase 50 532 1.3E-213 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 44 514 40.245 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 SUPERFAMILY SSF53697 6 539 5.0E-204 T 12-10-2018 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 263 276 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 PRINTS PR00662 Glucose-6-phosphate isomerase signature 473 487 9.6E-54 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 PRINTS PR00662 Glucose-6-phosphate isomerase signature 487 500 9.6E-54 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 PRINTS PR00662 Glucose-6-phosphate isomerase signature 455 473 9.6E-54 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 PRINTS PR00662 Glucose-6-phosphate isomerase signature 336 357 9.6E-54 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 PRINTS PR00662 Glucose-6-phosphate isomerase signature 148 167 9.6E-54 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_20450 c057734bcbeb15322e9961d277294fa8 541 PRINTS PR00662 Glucose-6-phosphate isomerase signature 259 277 9.6E-54 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFR_27240 43a2b4727ca83f6a2390685ed3ffcd40 189 SUPERFAMILY SSF52833 61 180 3.67E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_27240 43a2b4727ca83f6a2390685ed3ffcd40 189 Pfam PF00578 AhpC/TSA family 61 170 7.6E-13 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_27240 43a2b4727ca83f6a2390685ed3ffcd40 189 ProSitePatterns PS00194 Thioredoxin family active site. 83 101 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFR_27240 43a2b4727ca83f6a2390685ed3ffcd40 189 Gene3D G3DSA:3.40.30.10 55 189 1.8E-27 T 12-10-2018 AFR_11025 7d999eca87fffd07453e81c4f10ecfc9 272 SUPERFAMILY SSF53474 135 219 7.27E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11025 7d999eca87fffd07453e81c4f10ecfc9 272 Gene3D G3DSA:3.40.50.1820 33 262 7.0E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11025 7d999eca87fffd07453e81c4f10ecfc9 272 Pfam PF06259 Alpha/beta hydrolase 45 217 1.4E-46 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 AFR_18095 5a89ba35f4db83a7e80dcbd7c7b26bc8 983 Pfam PF00754 F5/8 type C domain 548 669 1.8E-11 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_18095 5a89ba35f4db83a7e80dcbd7c7b26bc8 983 Gene3D G3DSA:1.50.10.10 119 437 3.7E-23 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFR_18095 5a89ba35f4db83a7e80dcbd7c7b26bc8 983 Gene3D G3DSA:2.60.120.260 533 682 3.8E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_18095 5a89ba35f4db83a7e80dcbd7c7b26bc8 983 SUPERFAMILY SSF49785 546 680 3.91E-8 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_18095 5a89ba35f4db83a7e80dcbd7c7b26bc8 983 SUPERFAMILY SSF48208 61 492 3.84E-35 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_25720 04c06dea2d5fe4f181f168ade12b7762 854 Pfam PF02687 FtsX-like permease family 757 846 2.6E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_25720 04c06dea2d5fe4f181f168ade12b7762 854 Pfam PF02687 FtsX-like permease family 293 385 1.9E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_21790 b8cba92fd3aec4c259345a93191a0e78 504 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 51 442 2.2E-70 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AFR_21790 b8cba92fd3aec4c259345a93191a0e78 504 SUPERFAMILY SSF56317 206 475 2.22E-34 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_21790 b8cba92fd3aec4c259345a93191a0e78 504 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 480 14.836 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AFR_21790 b8cba92fd3aec4c259345a93191a0e78 504 Pfam PF00795 Carbon-nitrogen hydrolase 208 459 3.4E-16 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFR_21790 b8cba92fd3aec4c259345a93191a0e78 504 Gene3D G3DSA:3.60.110.10 206 473 8.6E-13 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_36950 1410b84f35a4c083ff738f316be3db43 130 Pfam PF10756 Bacterial PH domain 46 103 5.6E-9 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 AFR_36950 1410b84f35a4c083ff738f316be3db43 130 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 43 110 0.009 T 12-10-2018 IPR020535 Low molecular weight antigen Cfp6 AFR_25850 4357387c58827a0c38bf19b438e74533 218 Pfam PF13302 Acetyltransferase (GNAT) domain 34 173 3.8E-23 T 12-10-2018 IPR000182 GNAT domain AFR_25850 4357387c58827a0c38bf19b438e74533 218 Gene3D G3DSA:3.40.630.30 21 217 2.1E-48 T 12-10-2018 AFR_25850 4357387c58827a0c38bf19b438e74533 218 SUPERFAMILY SSF55729 25 198 3.54E-42 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_03880 077b3bf1f62d2a31365ba8b17a1e842f 476 Pfam PF01979 Amidohydrolase family 56 410 8.1E-32 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFR_03880 077b3bf1f62d2a31365ba8b17a1e842f 476 Gene3D G3DSA:3.20.20.140 61 421 5.0E-102 T 12-10-2018 AFR_03880 077b3bf1f62d2a31365ba8b17a1e842f 476 SUPERFAMILY SSF51556 59 360 3.26E-54 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_03880 077b3bf1f62d2a31365ba8b17a1e842f 476 SUPERFAMILY SSF51338 5 435 6.67E-28 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_03880 077b3bf1f62d2a31365ba8b17a1e842f 476 Gene3D G3DSA:2.30.40.10 12 416 5.0E-102 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFR_07565 73afdd972f8f8cacf82e4404cd78a0e6 243 Gene3D G3DSA:3.10.180.10 128 243 2.7E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_07565 73afdd972f8f8cacf82e4404cd78a0e6 243 Gene3D G3DSA:3.10.180.10 1 127 1.3E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_07565 73afdd972f8f8cacf82e4404cd78a0e6 243 SUPERFAMILY SSF54593 129 242 4.57E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_07565 73afdd972f8f8cacf82e4404cd78a0e6 243 SUPERFAMILY SSF54593 1 121 5.64E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_27920 8a3b25ac1c620091306bc883bd72d900 294 Gene3D G3DSA:3.30.450.180 116 282 2.6E-17 T 12-10-2018 AFR_27920 8a3b25ac1c620091306bc883bd72d900 294 Pfam PF13560 Helix-turn-helix domain 15 92 1.1E-9 T 12-10-2018 AFR_27920 8a3b25ac1c620091306bc883bd72d900 294 SUPERFAMILY SSF47413 37 87 4.93E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_14760 288a2c76310c64fe59b8c8986934dd55 113 Pfam PF12840 Helix-turn-helix domain 9 67 9.4E-15 T 12-10-2018 AFR_14760 288a2c76310c64fe59b8c8986934dd55 113 SUPERFAMILY SSF46785 6 100 2.15E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_14760 288a2c76310c64fe59b8c8986934dd55 113 Gene3D G3DSA:1.10.10.10 1 109 2.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_14760 288a2c76310c64fe59b8c8986934dd55 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 1.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_14760 288a2c76310c64fe59b8c8986934dd55 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_14760 288a2c76310c64fe59b8c8986934dd55 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_14760 288a2c76310c64fe59b8c8986934dd55 113 SMART SM00418 9 90 3.2E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_31265 f279ea34da9c1eb0de679b3dc2958193 316 Pfam PF00296 Luciferase-like monooxygenase 1 290 3.2E-47 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_31265 f279ea34da9c1eb0de679b3dc2958193 316 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 3 314 1.1E-134 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related AFR_31265 f279ea34da9c1eb0de679b3dc2958193 316 Gene3D G3DSA:3.20.20.30 1 315 4.3E-66 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_31265 f279ea34da9c1eb0de679b3dc2958193 316 SUPERFAMILY SSF51679 1 313 1.1E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_09280 22be2541db90ce82fa6f501deed778a4 240 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 240 41.861 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFR_09280 22be2541db90ce82fa6f501deed778a4 240 Pfam PF02654 Cobalamin-5-phosphate synthase 8 235 1.5E-48 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFR_09280 22be2541db90ce82fa6f501deed778a4 240 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 237 9.9E-33 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFR_21245 6e245b8c18169b7db5b27b2baf5b8b98 539 Pfam PF06276 Ferric iron reductase FhuF-like transporter 369 526 2.4E-28 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain AFR_21245 6e245b8c18169b7db5b27b2baf5b8b98 539 Gene3D G3DSA:1.10.510.40 343 537 5.7E-20 T 12-10-2018 AFR_21245 6e245b8c18169b7db5b27b2baf5b8b98 539 Pfam PF04183 IucA / IucC family 127 343 3.5E-35 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 AFR_16200 a471d625443fb64377160f5d557348ae 258 Pfam PF01453 D-mannose binding lectin 83 138 4.5E-10 T 12-10-2018 IPR001480 Bulb-type lectin domain AFR_16200 a471d625443fb64377160f5d557348ae 258 Pfam PF01453 D-mannose binding lectin 51 104 2.4E-10 T 12-10-2018 IPR001480 Bulb-type lectin domain AFR_16200 a471d625443fb64377160f5d557348ae 258 SMART SM00108 33 139 2.7E-14 T 12-10-2018 IPR001480 Bulb-type lectin domain AFR_16200 a471d625443fb64377160f5d557348ae 258 Gene3D G3DSA:2.90.10.10 25 84 3.8E-16 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_16200 a471d625443fb64377160f5d557348ae 258 Pfam PF00877 NlpC/P60 family 170 243 7.5E-5 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_16200 a471d625443fb64377160f5d557348ae 258 SUPERFAMILY SSF54001 137 246 3.92E-8 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_16200 a471d625443fb64377160f5d557348ae 258 Gene3D G3DSA:3.90.1720.10 133 249 1.1E-8 T 12-10-2018 AFR_16200 a471d625443fb64377160f5d557348ae 258 Gene3D G3DSA:2.90.10.20 85 132 4.6E-15 T 12-10-2018 AFR_16200 a471d625443fb64377160f5d557348ae 258 SUPERFAMILY SSF51110 42 136 8.64E-18 T 12-10-2018 IPR036426 Bulb-type lectin domain superfamily AFR_22525 68274e96a457b43e8aedf6e1b1681a40 402 SUPERFAMILY SSF47413 7 71 2.76E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_22525 68274e96a457b43e8aedf6e1b1681a40 402 Gene3D G3DSA:1.10.260.40 8 95 1.2E-13 T 12-10-2018 AFR_22525 68274e96a457b43e8aedf6e1b1681a40 402 SMART SM00530 14 70 4.8E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_22525 68274e96a457b43e8aedf6e1b1681a40 402 Pfam PF13560 Helix-turn-helix domain 11 71 1.4E-11 T 12-10-2018 AFR_11015 81caf0464dc11ee37c27f6a8b23aa1a5 316 Gene3D G3DSA:3.40.50.410 88 278 2.9E-38 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_11015 81caf0464dc11ee37c27f6a8b23aa1a5 316 Pfam PF13519 von Willebrand factor type A domain 89 199 4.8E-18 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_11015 81caf0464dc11ee37c27f6a8b23aa1a5 316 SUPERFAMILY SSF53300 86 277 1.47E-27 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_11015 81caf0464dc11ee37c27f6a8b23aa1a5 316 SMART SM00327 86 277 7.4E-19 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_02885 0611bebfdd21eb2b7ff68887ad730892 479 Gene3D G3DSA:1.20.1740.10 9 436 2.2E-26 T 12-10-2018 AFR_02885 0611bebfdd21eb2b7ff68887ad730892 479 PIRSF PIRSF006060 5 437 1.6E-29 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_02885 0611bebfdd21eb2b7ff68887ad730892 479 Pfam PF13520 Amino acid permease 19 398 3.4E-15 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_00025 6b6b695b44f2069c7bced38e948fb369 186 Pfam PF05258 Protein of unknown function (DUF721) 75 161 2.0E-26 T 12-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 AFR_38315 3435ffa5c676f00b512d29cd516c3d91 411 SUPERFAMILY SSF55486 42 390 2.42E-110 T 12-10-2018 AFR_38315 3435ffa5c676f00b512d29cd516c3d91 411 Gene3D G3DSA:1.20.150.30 43 174 7.1E-8 T 12-10-2018 AFR_38315 3435ffa5c676f00b512d29cd516c3d91 411 Pfam PF10103 Zincin-like metallopeptidase 43 389 2.8E-119 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 AFR_38315 3435ffa5c676f00b512d29cd516c3d91 411 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 43 390 1.1E-118 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 AFR_14960 55cfb0614cf7dfa204aed67ba41a613e 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 282 8.3E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_14960 55cfb0614cf7dfa204aed67ba41a613e 293 SUPERFAMILY SSF161098 55 279 9.16E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14960 55cfb0614cf7dfa204aed67ba41a613e 293 Gene3D G3DSA:1.10.3720.10 50 291 6.3E-70 T 12-10-2018 IPR035906 MetI-like superfamily AFR_27315 408f9648926f3311d802a152f0cf9bde 326 Gene3D G3DSA:3.40.50.720 1 181 6.4E-15 T 12-10-2018 AFR_27315 408f9648926f3311d802a152f0cf9bde 326 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 124 3.6E-8 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain AFR_25750 1cbaf5f19b599516a231cec7aa14c14f 177 SUPERFAMILY SSF55729 66 160 2.16E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_25750 1cbaf5f19b599516a231cec7aa14c14f 177 Pfam PF13302 Acetyltransferase (GNAT) domain 42 153 1.8E-12 T 12-10-2018 IPR000182 GNAT domain AFR_25750 1cbaf5f19b599516a231cec7aa14c14f 177 Gene3D G3DSA:3.40.630.30 5 173 5.7E-21 T 12-10-2018 AFR_07795 eb36ac2775ac55844d8eeddf965e9861 177 Pfam PF14024 Protein of unknown function (DUF4240) 1 131 3.5E-41 T 12-10-2018 IPR025334 Domain of unknown function (DUF4240 AFR_32305 f21ea709aa5181a8f0865e46600e5237 126 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 85 2.1E-4 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_32305 f21ea709aa5181a8f0865e46600e5237 126 Gene3D G3DSA:2.30.110.10 3 118 4.8E-11 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_32305 f21ea709aa5181a8f0865e46600e5237 126 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 3 123 3.1E-32 T 12-10-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative AFR_32305 f21ea709aa5181a8f0865e46600e5237 126 SUPERFAMILY SSF50475 6 114 3.1E-12 T 12-10-2018 AFR_20585 09e57f6a0b7af4423c48da86c9cd9e4d 399 Pfam PF12704 MacB-like periplasmic core domain 21 239 4.6E-36 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_20585 09e57f6a0b7af4423c48da86c9cd9e4d 399 Pfam PF02687 FtsX-like permease family 307 392 4.4E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_35290 fbc8165b2366407c55021c06eacd9da2 236 Pfam PF12502 Protein of unknown function (DUF3710) 36 206 5.5E-61 T 12-10-2018 IPR022183 Protein of unknown function DUF3710 AFR_26300 d813f9a164b3a43f7276bab53c3fcecc 304 SUPERFAMILY SSF51735 1 122 1.39E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_26300 d813f9a164b3a43f7276bab53c3fcecc 304 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 37 78 4.3E-6 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AFR_26300 d813f9a164b3a43f7276bab53c3fcecc 304 Gene3D G3DSA:3.40.50.720 32 128 4.3E-11 T 12-10-2018 AFR_33200 408807b3ccad637ae4f170323d32de2d 429 SUPERFAMILY SSF103473 3 395 6.54E-45 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_33200 408807b3ccad637ae4f170323d32de2d 429 Gene3D G3DSA:1.20.1250.20 1 181 9.1E-25 T 12-10-2018 AFR_33200 408807b3ccad637ae4f170323d32de2d 429 Pfam PF07690 Major Facilitator Superfamily 4 231 1.0E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_33200 408807b3ccad637ae4f170323d32de2d 429 Gene3D G3DSA:1.20.1250.20 196 397 2.2E-14 T 12-10-2018 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 136 147 - T 12-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 SUPERFAMILY SSF51621 19 931 6.91E-274 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 7 931 17.773 T 12-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 Pfam PF00311 Phosphoenolpyruvate carboxylase 131 931 7.4E-287 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 190 206 1.8E-59 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 608 637 1.8E-59 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 403 423 1.8E-59 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 135 148 1.8E-59 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 248 263 1.8E-59 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 566 586 1.8E-59 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 745 771 1.8E-59 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFR_05255 b9b4af417ed72c737524ebe6acfc2d5d 931 Gene3D G3DSA:1.20.1440.90 282 406 2.8E-9 T 12-10-2018 AFR_23145 42536bc1769f323fe941ef0350f23695 217 Pfam PF02525 Flavodoxin-like fold 4 167 8.9E-18 T 12-10-2018 IPR003680 Flavodoxin-like fold AFR_23145 42536bc1769f323fe941ef0350f23695 217 SUPERFAMILY SSF52218 1 192 1.13E-23 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_23145 42536bc1769f323fe941ef0350f23695 217 Gene3D G3DSA:3.40.50.360 1 208 1.1E-25 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 SUPERFAMILY SSF51735 3 208 1.99E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 Pfam PF00106 short chain dehydrogenase 3 176 1.2E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 125 153 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_33175 5f872fd8470574ca8f5710debaa557c6 231 Gene3D G3DSA:3.40.50.720 2 229 2.5E-32 T 12-10-2018 AFR_04035 a5d8f8a038360b549ca17bfb768d0bea 446 Pfam PF02386 Cation transport protein 40 426 2.9E-54 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 AFR_21375 61203f34aa941b4e8e2ea62d984ebca8 614 Gene3D G3DSA:3.40.50.300 42 243 6.6E-23 T 12-10-2018 AFR_21375 61203f34aa941b4e8e2ea62d984ebca8 614 Pfam PF00350 Dynamin family 42 188 7.8E-13 T 12-10-2018 IPR022812 Dynamin superfamily AFR_21375 61203f34aa941b4e8e2ea62d984ebca8 614 SUPERFAMILY SSF52540 34 237 1.69E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_40545 e90a5916ac7e44b7baddadb9b3a0d4db 364 Pfam PF01594 AI-2E family transporter 17 335 5.4E-59 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFR_32265 8f99f20f06a1da772b617ce6da264d1e 145 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 9.5E-32 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_32265 8f99f20f06a1da772b617ce6da264d1e 145 Gene3D G3DSA:2.30.110.10 1 144 2.3E-52 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_32265 8f99f20f06a1da772b617ce6da264d1e 145 Pfam PF04075 F420H(2)-dependent quinone reductase 14 143 1.6E-47 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_23785 e313c86fc90b9c437c303357044a0c83 270 Gene3D G3DSA:3.40.50.1110 47 243 1.4E-26 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_04730 410ee8df1c23dd496babdf4bae906b32 104 SUPERFAMILY SSF51182 16 90 3.27E-10 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_04730 410ee8df1c23dd496babdf4bae906b32 104 Gene3D G3DSA:2.60.120.10 6 99 2.6E-23 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_13775 fc6ade7fb1650b0ed6a0e0dd6ba0898c 700 Pfam PF03639 Glycosyl hydrolase family 81 344 616 1.2E-56 T 12-10-2018 IPR005200 Endo-1,3(4)-beta-glucanase GO:0052861 AFR_05705 3b1f5a8ebf4d1a4df3202cc15debf49c 118 PIRSF PIRSF009151 1 118 3.2E-57 T 12-10-2018 IPR008497 Protein of unknown function DUF779 AFR_05705 3b1f5a8ebf4d1a4df3202cc15debf49c 118 Pfam PF05610 Protein of unknown function (DUF779) 8 107 2.6E-45 T 12-10-2018 IPR008497 Protein of unknown function DUF779 AFR_26460 ae1b38b15805abfef878fa87641c429e 163 SUPERFAMILY SSF47598 98 146 1.37E-10 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFR_26460 ae1b38b15805abfef878fa87641c429e 163 Pfam PF05534 HicB family 103 133 7.1E-5 T 12-10-2018 IPR008651 Uncharacterised protein family HicB AFR_26460 ae1b38b15805abfef878fa87641c429e 163 Gene3D G3DSA:1.20.5.780 98 160 2.6E-6 T 12-10-2018 AFR_31615 5b84dbb3557b388684def4ab2fc39d0d 243 Gene3D G3DSA:3.90.550.10 2 228 2.9E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_31615 5b84dbb3557b388684def4ab2fc39d0d 243 Pfam PF00535 Glycosyl transferase family 2 6 146 2.0E-23 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_31615 5b84dbb3557b388684def4ab2fc39d0d 243 SUPERFAMILY SSF53448 5 207 3.38E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 PRINTS PR00834 HtrA/DegQ protease family signature 127 147 2.3E-28 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 PRINTS PR00834 HtrA/DegQ protease family signature 204 221 2.3E-28 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 2.3E-28 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 PRINTS PR00834 HtrA/DegQ protease family signature 106 118 2.3E-28 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 PRINTS PR00834 HtrA/DegQ protease family signature 167 191 2.3E-28 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 Gene3D G3DSA:2.40.10.10 57 153 1.1E-18 T 12-10-2018 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 Gene3D G3DSA:2.40.10.10 163 262 2.1E-27 T 12-10-2018 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 Pfam PF13365 Trypsin-like peptidase domain 97 233 9.2E-24 T 12-10-2018 AFR_32565 992854cef1639abdc9fdaa5b1a66b08a 271 SUPERFAMILY SSF50494 67 259 6.25E-44 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_36790 93d6fc2a1c2dd7d256220d863a642782 321 SUPERFAMILY SSF53300 87 199 1.67E-5 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_36790 93d6fc2a1c2dd7d256220d863a642782 321 Pfam PF01882 Protein of unknown function DUF58 43 128 3.3E-17 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_18760 7774331e2102ec4532d6ac63ddd705c2 216 Pfam PF01323 DSBA-like thioredoxin domain 6 206 7.9E-41 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 AFR_18760 7774331e2102ec4532d6ac63ddd705c2 216 Gene3D G3DSA:3.40.30.10 4 210 7.0E-73 T 12-10-2018 AFR_18760 7774331e2102ec4532d6ac63ddd705c2 216 SUPERFAMILY SSF52833 3 211 5.35E-39 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_27655 e017a8883b5ff73a798b0284643a9094 135 Gene3D G3DSA:1.10.10.10 1 135 1.9E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27655 e017a8883b5ff73a798b0284643a9094 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 5.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_27655 e017a8883b5ff73a798b0284643a9094 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 5.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_27655 e017a8883b5ff73a798b0284643a9094 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 5.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_27655 e017a8883b5ff73a798b0284643a9094 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 5.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_27655 e017a8883b5ff73a798b0284643a9094 135 Pfam PF01047 MarR family 31 87 1.7E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_27655 e017a8883b5ff73a798b0284643a9094 135 SUPERFAMILY SSF46785 3 135 6.72E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_27655 e017a8883b5ff73a798b0284643a9094 135 SMART SM00347 23 123 2.7E-21 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_27655 e017a8883b5ff73a798b0284643a9094 135 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFR_27885 4d71ba84d7bb68d5b15258245c88e7d2 132 Gene3D G3DSA:1.10.1740.10 17 96 1.8E-12 T 12-10-2018 AFR_27885 4d71ba84d7bb68d5b15258245c88e7d2 132 SUPERFAMILY SSF88946 14 93 9.02E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 SMART SM01008 36 145 6.8E-53 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 SUPERFAMILY SSF54665 17 166 5.1E-47 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 SUPERFAMILY SSF56003 137 791 1.83E-201 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 Gene3D G3DSA:3.30.365.10 389 768 1.1E-145 T 12-10-2018 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 Gene3D G3DSA:3.30.365.10 205 301 2.6E-77 T 12-10-2018 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 Gene3D G3DSA:3.90.1170.50 8 144 5.5E-52 T 12-10-2018 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 Gene3D G3DSA:3.30.365.10 476 643 1.1E-145 T 12-10-2018 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 Gene3D G3DSA:3.30.365.10 148 373 2.6E-77 T 12-10-2018 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 37 144 1.1E-36 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 169 728 2.4E-171 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFR_27200 25dda7e71f760ebfc0b25b8dee2634ff 798 TIGRFAM TIGR02416 CO_dehy_Mo_lg: carbon-monoxide dehydrogenase, large subunit 30 789 0.0 T 12-10-2018 IPR012780 Carbon-monoxide dehydrogenase, large subunit GO:0005507|GO:0018492|GO:0030151 MetaCyc: PWY-7750 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 SUPERFAMILY SSF55424 343 459 6.36E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 Gene3D G3DSA:3.50.50.60 1 319 3.1E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 452 6.4E-23 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 SUPERFAMILY SSF51905 1 324 3.33E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 30 45 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 252 266 2.7E-41 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 1.7E-11 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 1.7E-11 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.7E-11 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 267 1.7E-11 T 12-10-2018 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 Gene3D G3DSA:3.30.390.30 345 461 1.3E-27 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 307 4.7E-42 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 Gene3D G3DSA:3.50.50.60 148 265 3.1E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_17780 57dd06843d72ee1d6d99178089bfc5b3 462 PIRSF PIRSF000350 1 460 2.9E-77 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFR_29910 b730dc673120975f895b91b4f0bd76b8 552 PRINTS PR01806 Virulence factor MviN signature 156 180 2.2E-13 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_29910 b730dc673120975f895b91b4f0bd76b8 552 PRINTS PR01806 Virulence factor MviN signature 379 398 2.2E-13 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_29910 b730dc673120975f895b91b4f0bd76b8 552 PRINTS PR01806 Virulence factor MviN signature 78 94 2.2E-13 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_29910 b730dc673120975f895b91b4f0bd76b8 552 PRINTS PR01806 Virulence factor MviN signature 59 78 2.2E-13 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_29910 b730dc673120975f895b91b4f0bd76b8 552 PRINTS PR01806 Virulence factor MviN signature 435 452 2.2E-13 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_29910 b730dc673120975f895b91b4f0bd76b8 552 PRINTS PR01806 Virulence factor MviN signature 180 201 2.2E-13 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_29910 b730dc673120975f895b91b4f0bd76b8 552 Pfam PF03023 MviN-like protein 60 485 1.2E-52 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFR_22115 77bcb3cf35dae2596579780892b0dd2c 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 88 1.8E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_22115 77bcb3cf35dae2596579780892b0dd2c 135 SUPERFAMILY SSF54593 4 119 7.79E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_22115 77bcb3cf35dae2596579780892b0dd2c 135 Gene3D G3DSA:3.10.180.10 3 119 6.0E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_13430 91f54ddd8e6a556286c076aa8a9104a7 181 SUPERFAMILY SSF55781 35 176 1.11E-21 T 12-10-2018 AFR_13430 91f54ddd8e6a556286c076aa8a9104a7 181 Pfam PF01590 GAF domain 39 171 5.5E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_13430 91f54ddd8e6a556286c076aa8a9104a7 181 SMART SM00065 33 181 0.0094 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_13430 91f54ddd8e6a556286c076aa8a9104a7 181 Gene3D G3DSA:3.30.450.40 25 180 2.2E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_17755 1395babe936aebcf07c4a363ac6666dd 325 Gene3D G3DSA:2.60.40.1260 214 315 1.0E-5 T 12-10-2018 IPR036415 Lamin tail domain superfamily AFR_17755 1395babe936aebcf07c4a363ac6666dd 325 SUPERFAMILY SSF50199 44 190 5.62E-13 T 12-10-2018 AFR_17755 1395babe936aebcf07c4a363ac6666dd 325 Pfam PF00932 Lamin Tail Domain 207 315 1.1E-21 T 12-10-2018 IPR001322 Lamin tail domain AFR_17755 1395babe936aebcf07c4a363ac6666dd 325 Gene3D G3DSA:2.40.50.90 42 194 7.1E-11 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily AFR_17755 1395babe936aebcf07c4a363ac6666dd 325 SUPERFAMILY SSF74853 218 317 6.8E-16 T 12-10-2018 IPR036415 Lamin tail domain superfamily AFR_22340 571af3c9a07f671c143e3ccff76aac21 367 SUPERFAMILY SSF51679 4 364 7.6E-66 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22340 571af3c9a07f671c143e3ccff76aac21 367 Pfam PF00296 Luciferase-like monooxygenase 19 335 4.2E-34 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_22340 571af3c9a07f671c143e3ccff76aac21 367 Gene3D G3DSA:3.20.20.30 1 366 9.8E-89 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_37830 94dfd3338ca602c77571419cdde046fd 218 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 28 211 5.1E-31 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_37830 94dfd3338ca602c77571419cdde046fd 218 Pfam PF02096 60Kd inner membrane protein 29 211 1.8E-29 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFR_41310 bfca438a1eaac1784337cd1dc162c997 278 Pfam PF01040 UbiA prenyltransferase family 20 259 1.1E-22 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFR_41310 bfca438a1eaac1784337cd1dc162c997 278 Gene3D G3DSA:1.10.357.140 16 172 4.3E-7 T 12-10-2018 AFR_21540 0787eb1791c53e935443802b8cd5a49c 307 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 3 305 3.6E-81 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 AFR_00070 6c3e51264b22eead437a727c3b02aa5e 427 Gene3D G3DSA:3.40.50.150 141 413 2.6E-95 T 12-10-2018 AFR_00070 6c3e51264b22eead437a727c3b02aa5e 427 SUPERFAMILY SSF53335 142 409 4.85E-75 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_00070 6c3e51264b22eead437a727c3b02aa5e 427 PIRSF PIRSF003085 5 426 8.2E-128 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AFR_00070 6c3e51264b22eead437a727c3b02aa5e 427 Pfam PF02353 Mycolic acid cyclopropane synthetase 133 405 1.6E-92 T 12-10-2018 AFR_10370 f20fc37dcc360231e27335c852f5b1bb 288 Pfam PF13622 Thioesterase-like superfamily 31 281 6.9E-59 T 12-10-2018 AFR_10370 f20fc37dcc360231e27335c852f5b1bb 288 SUPERFAMILY SSF54637 6 115 2.14E-38 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_10370 f20fc37dcc360231e27335c852f5b1bb 288 SUPERFAMILY SSF54637 117 283 4.56E-46 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_10370 f20fc37dcc360231e27335c852f5b1bb 288 Gene3D G3DSA:3.10.129.90 3 285 5.2E-100 T 12-10-2018 AFR_18320 0bb04120c6941afd828396a8f62af826 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 24 285 1.2E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_11110 4fafa4eff631d73f7fecd28ad6e2ec98 250 Gene3D G3DSA:3.20.20.60 1 221 5.1E-68 T 12-10-2018 AFR_11110 4fafa4eff631d73f7fecd28ad6e2ec98 250 Pfam PF13714 Phosphoenolpyruvate phosphomutase 4 220 8.4E-72 T 12-10-2018 AFR_11110 4fafa4eff631d73f7fecd28ad6e2ec98 250 SUPERFAMILY SSF51621 3 225 2.83E-58 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_17195 95cd8269338c2fe2d6926e9fe139e075 157 Pfam PF06271 RDD family 23 151 1.9E-22 T 12-10-2018 IPR010432 RDD AFR_22135 d9d9948fb17638444e414c0fdf03bf29 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 3.6E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22135 d9d9948fb17638444e414c0fdf03bf29 192 Gene3D G3DSA:1.10.10.60 2 51 6.2E-19 T 12-10-2018 AFR_22135 d9d9948fb17638444e414c0fdf03bf29 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFR_22135 d9d9948fb17638444e414c0fdf03bf29 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 9.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22135 d9d9948fb17638444e414c0fdf03bf29 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 9.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22135 d9d9948fb17638444e414c0fdf03bf29 192 Gene3D G3DSA:1.10.357.10 53 192 8.7E-33 T 12-10-2018 AFR_22135 d9d9948fb17638444e414c0fdf03bf29 192 SUPERFAMILY SSF46689 4 83 8.03E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_39305 7d6f52d668956a6cff7e83612693538a 187 Pfam PF04138 GtrA-like protein 21 140 6.4E-18 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 AFR_42670 807f215c13ff9bfbe6ee8846502a2856 82 Gene3D G3DSA:3.10.20.30 4 82 3.7E-13 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_42670 807f215c13ff9bfbe6ee8846502a2856 82 SUPERFAMILY SSF54285 6 82 3.92E-10 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFR_42670 807f215c13ff9bfbe6ee8846502a2856 82 Pfam PF02597 ThiS family 7 82 1.1E-5 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFR_09925 b9851da2691d68ce3e9ee6e343b32833 422 Pfam PF01882 Protein of unknown function DUF58 189 273 2.4E-22 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_25755 ff61d3e05a4fbe6a432fee2ad2baccb7 166 Gene3D G3DSA:1.10.10.10 12 165 6.8E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25755 ff61d3e05a4fbe6a432fee2ad2baccb7 166 Pfam PF01047 MarR family 45 103 3.6E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_25755 ff61d3e05a4fbe6a432fee2ad2baccb7 166 SMART SM00347 38 141 6.6E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_25755 ff61d3e05a4fbe6a432fee2ad2baccb7 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 8.4E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_25755 ff61d3e05a4fbe6a432fee2ad2baccb7 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 8.4E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_25755 ff61d3e05a4fbe6a432fee2ad2baccb7 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 8.4E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_25755 ff61d3e05a4fbe6a432fee2ad2baccb7 166 SUPERFAMILY SSF46785 37 156 3.21E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_38575 9253cea08b1ae12a8df8d3083bbf3d07 285 Gene3D G3DSA:3.20.20.100 8 284 7.9E-58 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_38575 9253cea08b1ae12a8df8d3083bbf3d07 285 PRINTS PR00069 Aldo-keto reductase signature 142 159 1.5E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38575 9253cea08b1ae12a8df8d3083bbf3d07 285 PRINTS PR00069 Aldo-keto reductase signature 46 70 1.5E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38575 9253cea08b1ae12a8df8d3083bbf3d07 285 PRINTS PR00069 Aldo-keto reductase signature 217 241 1.5E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38575 9253cea08b1ae12a8df8d3083bbf3d07 285 PRINTS PR00069 Aldo-keto reductase signature 111 129 1.5E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_38575 9253cea08b1ae12a8df8d3083bbf3d07 285 Pfam PF00248 Aldo/keto reductase family 16 282 8.4E-43 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_38575 9253cea08b1ae12a8df8d3083bbf3d07 285 SUPERFAMILY SSF51430 11 283 3.14E-58 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_03065 ac00c8347e585341bf6bafceba724a4b 313 Pfam PF04261 Dyp-type peroxidase family 7 302 1.0E-93 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 AFR_03065 ac00c8347e585341bf6bafceba724a4b 313 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 7 302 8.0E-84 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 AFR_03065 ac00c8347e585341bf6bafceba724a4b 313 SUPERFAMILY SSF54909 5 306 1.41E-105 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_07860 3d7acb8a5ef5723745f82a245f46c650 347 Pfam PF01032 FecCD transport family 38 343 1.1E-77 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_07860 3d7acb8a5ef5723745f82a245f46c650 347 SUPERFAMILY SSF81345 19 343 8.89E-69 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_07860 3d7acb8a5ef5723745f82a245f46c650 347 Gene3D G3DSA:1.10.3470.10 24 347 8.9E-84 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_16145 36285db7a537f03b6913813dfafb656e 219 Pfam PF00072 Response regulator receiver domain 4 116 1.9E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_16145 36285db7a537f03b6913813dfafb656e 219 SUPERFAMILY SSF46894 145 215 3.3E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_16145 36285db7a537f03b6913813dfafb656e 219 SMART SM00421 152 209 4.6E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16145 36285db7a537f03b6913813dfafb656e 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 3.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16145 36285db7a537f03b6913813dfafb656e 219 SUPERFAMILY SSF52172 2 135 1.01E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFR_16145 36285db7a537f03b6913813dfafb656e 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16145 36285db7a537f03b6913813dfafb656e 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16145 36285db7a537f03b6913813dfafb656e 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_16145 36285db7a537f03b6913813dfafb656e 219 Gene3D G3DSA:3.40.50.12740 2 215 5.4E-66 T 12-10-2018 AFR_16145 36285db7a537f03b6913813dfafb656e 219 SMART SM00448 2 117 3.8E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40225 d3ef48c347bcfd7e7bc2ec63ea894531 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 63 2.6E-19 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFR_40225 d3ef48c347bcfd7e7bc2ec63ea894531 70 Pfam PF12728 Helix-turn-helix domain 16 64 6.3E-13 T 12-10-2018 AFR_40225 d3ef48c347bcfd7e7bc2ec63ea894531 70 Gene3D G3DSA:1.10.1660.10 14 65 6.4E-10 T 12-10-2018 AFR_39010 50b580a81e402664324c094b520db3d1 109 Pfam PF13586 Transposase DDE domain 1 97 1.6E-18 T 12-10-2018 IPR025668 Transposase DDE domain AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 SUPERFAMILY SSF52518 69 484 2.33E-128 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 18 905 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 Gene3D G3DSA:3.40.50.920 725 906 2.3E-66 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 Gene3D G3DSA:3.40.50.970 489 723 5.0E-104 T 12-10-2018 AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 311 2.8E-10 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 SUPERFAMILY SSF52922 721 904 1.03E-53 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 SUPERFAMILY SSF52518 490 717 2.94E-90 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 PIRSF PIRSF000156 9 907 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AFR_08765 27a0aa349f0120cdbfe0d28b52a74f77 912 Gene3D G3DSA:3.40.50.970 68 488 4.7E-129 T 12-10-2018 AFR_09905 4d1aa533fbf63438eefedc6d5d073650 380 Gene3D G3DSA:3.40.720.10 46 379 1.0E-30 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_09905 4d1aa533fbf63438eefedc6d5d073650 380 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 72 354 2.4E-25 T 12-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 AFR_09905 4d1aa533fbf63438eefedc6d5d073650 380 SUPERFAMILY SSF53649 52 379 2.09E-48 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_33340 bc36440a5229ddff5c722a998d2ddb05 269 Pfam PF10067 Predicted membrane protein (DUF2306) 66 218 1.1E-37 T 12-10-2018 IPR018750 Protein of unknown function DUF2306, membrane AFR_05785 9f8d41af6e1ff618a467cba8e83ced58 206 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 2.3E-23 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 AFR_05785 9f8d41af6e1ff618a467cba8e83ced58 206 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 203 23.411 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid AFR_05785 9f8d41af6e1ff618a467cba8e83ced58 206 SUPERFAMILY SSF69754 3 111 1.7E-28 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFR_05785 9f8d41af6e1ff618a467cba8e83ced58 206 Gene3D G3DSA:3.30.160.100 3 105 1.1E-24 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFR_05785 9f8d41af6e1ff618a467cba8e83ced58 206 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 146 199 1.1E-23 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal AFR_05785 9f8d41af6e1ff618a467cba8e83ced58 206 Gene3D G3DSA:3.30.505.50 157 202 1.2E-18 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily AFR_05785 9f8d41af6e1ff618a467cba8e83ced58 206 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 2 102 8.8E-29 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 AFR_19565 ed22cf6da7f2833aa921a0a8930dd666 160 Pfam PF01668 SmpB protein 10 150 4.0E-58 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_19565 ed22cf6da7f2833aa921a0a8930dd666 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 2.8E-55 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_19565 ed22cf6da7f2833aa921a0a8930dd666 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 70.004 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_19565 ed22cf6da7f2833aa921a0a8930dd666 160 Gene3D G3DSA:2.40.280.10 3 129 9.0E-47 T 12-10-2018 IPR023620 Small protein B AFR_19565 ed22cf6da7f2833aa921a0a8930dd666 160 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site AFR_19565 ed22cf6da7f2833aa921a0a8930dd666 160 SUPERFAMILY SSF74982 4 133 9.29E-50 T 12-10-2018 IPR023620 Small protein B AFR_19565 ed22cf6da7f2833aa921a0a8930dd666 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 1.0E-44 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFR_31825 7b2296827344b22a652ff1db50eb8a5d 290 SUPERFAMILY SSF51679 7 286 1.44E-54 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_31825 7b2296827344b22a652ff1db50eb8a5d 290 Gene3D G3DSA:3.20.20.30 1 272 5.9E-59 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_31825 7b2296827344b22a652ff1db50eb8a5d 290 Pfam PF00296 Luciferase-like monooxygenase 13 218 5.1E-50 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 15 414 4.1E-114 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 15 418 30.974 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 20 417 3.1E-120 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 PIRSF PIRSF000505 6 418 3.0E-133 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 Gene3D G3DSA:3.65.10.10 20 410 4.5E-135 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 ProSitePatterns PS00885 EPSP synthase signature 2. 333 351 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 SUPERFAMILY SSF55205 16 417 2.35E-113 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFR_09940 3125bf6368cf6dc3fdb8fc8dd2399c8f 418 Gene3D G3DSA:3.65.10.10 27 238 4.5E-135 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFR_25580 4bcbef76081612c870ef37e056a74b7a 322 Gene3D G3DSA:2.60.120.10 31 264 3.2E-62 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_25580 4bcbef76081612c870ef37e056a74b7a 322 SUPERFAMILY SSF51182 35 301 6.41E-70 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_25580 4bcbef76081612c870ef37e056a74b7a 322 Pfam PF05726 Pirin C-terminal cupin domain 191 287 2.4E-19 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 AFR_25580 4bcbef76081612c870ef37e056a74b7a 322 Pfam PF02678 Pirin 38 139 5.0E-28 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFR_25580 4bcbef76081612c870ef37e056a74b7a 322 PIRSF PIRSF006232 20 302 3.7E-75 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFR_20275 ef63e928ef2b1e100b96370d3f288220 231 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 183 227 4.9E-10 T 12-10-2018 IPR004176 Clp, N-terminal AFR_20275 ef63e928ef2b1e100b96370d3f288220 231 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 107 153 5.3E-9 T 12-10-2018 IPR004176 Clp, N-terminal AFR_20275 ef63e928ef2b1e100b96370d3f288220 231 SUPERFAMILY SSF81923 95 227 1.28E-22 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_20275 ef63e928ef2b1e100b96370d3f288220 231 Gene3D G3DSA:1.10.1780.10 92 230 2.8E-36 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 SUPERFAMILY SSF53613 1 328 4.07E-49 T 12-10-2018 IPR029056 Ribokinase-like AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 Gene3D G3DSA:3.40.1190.20 230 351 2.1E-21 T 12-10-2018 IPR029056 Ribokinase-like AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 Gene3D G3DSA:3.40.1190.20 1 227 2.7E-71 T 12-10-2018 IPR029056 Ribokinase-like AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 PIRSF PIRSF000535 1 204 1.4E-61 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 PIRSF PIRSF000535 243 351 1.4E-14 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 Pfam PF00294 pfkB family carbohydrate kinase 22 194 4.0E-23 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_22495 fc55b77ee77f9185dd340e437fa5987c 351 Pfam PF00294 pfkB family carbohydrate kinase 246 331 3.1E-9 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_29350 dc8cceef3a2c456cbfb79b9c8b0d939e 156 SUPERFAMILY SSF54427 12 137 4.0E-30 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_29350 dc8cceef3a2c456cbfb79b9c8b0d939e 156 Gene3D G3DSA:3.10.450.50 2 144 8.5E-33 T 12-10-2018 AFR_29350 dc8cceef3a2c456cbfb79b9c8b0d939e 156 Pfam PF12680 SnoaL-like domain 15 123 5.4E-15 T 12-10-2018 IPR037401 SnoaL-like domain AFR_22530 972f1cbac934b63b3e684c6d9d787683 272 SUPERFAMILY SSF161098 3 272 3.27E-68 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22530 972f1cbac934b63b3e684c6d9d787683 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 262 5.7E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_22530 972f1cbac934b63b3e684c6d9d787683 272 Gene3D G3DSA:1.10.3720.10 8 263 7.7E-64 T 12-10-2018 IPR035906 MetI-like superfamily AFR_05635 3f0f304ccbbee8b6b9bbe46726f088f4 371 Gene3D G3DSA:3.90.550.10 7 365 7.3E-111 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05635 3f0f304ccbbee8b6b9bbe46726f088f4 371 SUPERFAMILY SSF159283 294 363 4.97E-16 T 12-10-2018 AFR_05635 3f0f304ccbbee8b6b9bbe46726f088f4 371 SUPERFAMILY SSF53448 9 285 6.0E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05635 3f0f304ccbbee8b6b9bbe46726f088f4 371 Pfam PF01050 Mannose-6-phosphate isomerase 330 367 7.7E-7 T 12-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFR_05635 3f0f304ccbbee8b6b9bbe46726f088f4 371 Pfam PF00483 Nucleotidyl transferase 10 288 4.1E-46 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFR_21070 d677d6a9bb252d858368480802fa8468 110 PIRSF PIRSF018579 1 110 1.3E-44 T 12-10-2018 IPR009709 Protein of unknown function DUF1290 AFR_21070 d677d6a9bb252d858368480802fa8468 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 2.5E-34 T 12-10-2018 IPR009709 Protein of unknown function DUF1290 AFR_05080 bb81070540f48e4bf1881da547c7601a 203 Gene3D G3DSA:2.70.70.10 40 188 1.6E-40 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_05080 bb81070540f48e4bf1881da547c7601a 203 SUPERFAMILY SSF51261 63 184 4.13E-45 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_05080 bb81070540f48e4bf1881da547c7601a 203 Pfam PF01551 Peptidase family M23 86 180 9.8E-28 T 12-10-2018 IPR016047 Peptidase M23 AFR_08970 fdb2de657775b1e8e486d512ea4f2c96 304 SUPERFAMILY SSF53686 6 296 3.8E-71 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_08970 fdb2de657775b1e8e486d512ea4f2c96 304 Gene3D G3DSA:3.40.50.1100 42 139 7.4E-82 T 12-10-2018 AFR_08970 fdb2de657775b1e8e486d512ea4f2c96 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 295 8.8E-64 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_08970 fdb2de657775b1e8e486d512ea4f2c96 304 Gene3D G3DSA:3.40.50.1100 7 299 7.4E-82 T 12-10-2018 AFR_20430 e3fd6f86d1ee744d8e6b145bf6b210af 199 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 197 8.5E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_20430 e3fd6f86d1ee744d8e6b145bf6b210af 199 Gene3D G3DSA:1.10.3720.10 1 199 2.5E-45 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20430 e3fd6f86d1ee744d8e6b145bf6b210af 199 SUPERFAMILY SSF161098 1 185 1.16E-39 T 12-10-2018 IPR035906 MetI-like superfamily AFR_16055 2402d3a3d4f188e6f72966be84d4698e 294 Gene3D G3DSA:3.40.50.300 33 280 6.2E-32 T 12-10-2018 AFR_16055 2402d3a3d4f188e6f72966be84d4698e 294 SUPERFAMILY SSF52540 46 283 7.36E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16055 2402d3a3d4f188e6f72966be84d4698e 294 Pfam PF00685 Sulfotransferase domain 97 277 6.7E-18 T 12-10-2018 IPR000863 Sulfotransferase domain GO:0008146 AFR_29665 005c805dd87fc1565f0b92460dbcd9bb 226 SUPERFAMILY SSF52540 5 179 5.69E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_29665 005c805dd87fc1565f0b92460dbcd9bb 226 Gene3D G3DSA:3.40.50.300 136 193 2.7E-6 T 12-10-2018 AFR_30200 d4b65c43fe653c1a33975dd0c5e9f03f 307 Gene3D G3DSA:3.40.50.300 1 263 1.1E-51 T 12-10-2018 AFR_30200 d4b65c43fe653c1a33975dd0c5e9f03f 307 SUPERFAMILY SSF52540 2 300 1.03E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30200 d4b65c43fe653c1a33975dd0c5e9f03f 307 Pfam PF13614 AAA domain 1 201 5.0E-37 T 12-10-2018 IPR025669 AAA domain AFR_24455 a3707fdd51d52cd7997dc0c3bac9961f 233 SUPERFAMILY SSF56112 10 215 1.63E-7 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_33305 704cb5dd07645225eeac556e0c5c73dc 561 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 74 151 1.7E-13 T 12-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 AFR_33305 704cb5dd07645225eeac556e0c5c73dc 561 Gene3D G3DSA:2.160.20.10 159 486 1.5E-22 T 12-10-2018 IPR012334 Pectin lyase fold AFR_33305 704cb5dd07645225eeac556e0c5c73dc 561 SUPERFAMILY SSF51126 146 558 1.96E-36 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_40490 ab22698109a600714dfa5ba9a1438e78 340 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 11 67 3.7E-22 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain AFR_40490 ab22698109a600714dfa5ba9a1438e78 340 Pfam PF00691 OmpA family 183 280 3.6E-14 T 12-10-2018 IPR006665 OmpA-like domain AFR_40490 ab22698109a600714dfa5ba9a1438e78 340 Gene3D G3DSA:3.30.1330.60 125 296 9.3E-41 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFR_40490 ab22698109a600714dfa5ba9a1438e78 340 SUPERFAMILY SSF103088 174 286 2.09E-23 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFR_20580 f0ab675214da7cb2540b330b34e133e0 244 Pfam PF00005 ABC transporter 25 173 5.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_20580 f0ab675214da7cb2540b330b34e133e0 244 Gene3D G3DSA:3.40.50.300 3 235 1.2E-64 T 12-10-2018 AFR_20580 f0ab675214da7cb2540b330b34e133e0 244 SUPERFAMILY SSF52540 5 226 5.18E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20580 f0ab675214da7cb2540b330b34e133e0 244 SMART SM00382 34 221 2.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_20580 f0ab675214da7cb2540b330b34e133e0 244 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_11505 db0009ba238306c28cb0edee15d3859e 246 Gene3D G3DSA:3.40.50.150 8 242 1.3E-79 T 12-10-2018 AFR_11505 db0009ba238306c28cb0edee15d3859e 246 SUPERFAMILY SSF53335 10 245 2.3E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_11505 db0009ba238306c28cb0edee15d3859e 246 Pfam PF13649 Methyltransferase domain 46 139 3.4E-12 T 12-10-2018 AFR_11505 db0009ba238306c28cb0edee15d3859e 246 Gene3D G3DSA:2.20.25.570 147 203 1.3E-79 T 12-10-2018 AFR_30705 3a4d600720f2fdc692b37eb3bac61f04 153 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 7 149 22.467 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFR_30705 3a4d600720f2fdc692b37eb3bac61f04 153 SMART SM00732 7 114 1.2E-21 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFR_30705 3a4d600720f2fdc692b37eb3bac61f04 153 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 10 146 9.7E-28 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFR_30705 3a4d600720f2fdc692b37eb3bac61f04 153 Gene3D G3DSA:3.30.420.140 6 153 1.1E-42 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 AFR_30705 3a4d600720f2fdc692b37eb3bac61f04 153 Pfam PF03652 Holliday junction resolvase 8 146 4.9E-40 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFR_30705 3a4d600720f2fdc692b37eb3bac61f04 153 SUPERFAMILY SSF53098 7 148 3.64E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_41530 ad107711d705292a26f96c9632afbf28 136 Gene3D G3DSA:3.30.1330.40 2 134 5.5E-23 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_41530 ad107711d705292a26f96c9632afbf28 136 SUPERFAMILY SSF55298 6 134 5.81E-22 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_41530 ad107711d705292a26f96c9632afbf28 136 Pfam PF01042 Endoribonuclease L-PSP 15 131 7.7E-15 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 SUPERFAMILY SSF46785 11 138 3.22E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 Gene3D G3DSA:1.10.10.10 5 139 1.2E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 Pfam PF12802 MarR family 42 91 9.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_33555 9c236c909892cbe2e1b86a55a327d075 143 SMART SM00347 28 128 1.3E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_42520 74c2716b18c57dc47310c865fce0cb95 262 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 250 1.1E-40 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFR_42520 74c2716b18c57dc47310c865fce0cb95 262 SUPERFAMILY SSF51695 2 256 9.16E-65 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_42520 74c2716b18c57dc47310c865fce0cb95 262 Gene3D G3DSA:3.20.20.190 1 257 8.8E-70 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_19190 aafc0619083f13252909312f810ce6a3 417 SUPERFAMILY SSF53182 166 414 2.88E-21 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 AFR_19190 aafc0619083f13252909312f810ce6a3 417 Gene3D G3DSA:3.40.630.20 167 309 9.8E-6 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 AFR_24645 8cc92f62439fd8904df58bacf5235ac1 322 Gene3D G3DSA:3.20.20.100 1 315 7.4E-62 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_24645 8cc92f62439fd8904df58bacf5235ac1 322 SUPERFAMILY SSF51430 4 311 1.31E-60 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_24645 8cc92f62439fd8904df58bacf5235ac1 322 Pfam PF00248 Aldo/keto reductase family 8 308 2.4E-42 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_36855 ce95cc1f91f9f7de3123596101b1ca73 365 Gene3D G3DSA:3.20.10.10 178 347 1.7E-133 T 12-10-2018 AFR_36855 ce95cc1f91f9f7de3123596101b1ca73 365 Gene3D G3DSA:3.30.470.10 32 360 1.7E-133 T 12-10-2018 AFR_36855 ce95cc1f91f9f7de3123596101b1ca73 365 Pfam PF01063 Amino-transferase class IV 77 319 1.4E-30 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFR_36855 ce95cc1f91f9f7de3123596101b1ca73 365 PIRSF PIRSF006468 8 365 1.5E-128 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 AFR_36855 ce95cc1f91f9f7de3123596101b1ca73 365 SUPERFAMILY SSF56752 7 362 4.71E-113 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFR_36855 ce95cc1f91f9f7de3123596101b1ca73 365 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 51 364 5.1E-126 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 AFR_07700 a376e08c43a0ecde4233de9f5a80ec98 517 SUPERFAMILY SSF50370 338 501 4.34E-10 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_07700 a376e08c43a0ecde4233de9f5a80ec98 517 Gene3D G3DSA:2.80.10.50 339 510 1.1E-10 T 12-10-2018 AFR_07700 a376e08c43a0ecde4233de9f5a80ec98 517 Gene3D G3DSA:2.80.10.50 180 306 1.4E-9 T 12-10-2018 AFR_07700 a376e08c43a0ecde4233de9f5a80ec98 517 SUPERFAMILY SSF50370 182 374 6.62E-12 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_22500 5e0c0c1e4a0aea34683323e75fbbce39 276 Pfam PF03537 Glycoside-hydrolase family GH114 47 263 5.3E-51 T 12-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain AFR_22500 5e0c0c1e4a0aea34683323e75fbbce39 276 SUPERFAMILY SSF51445 48 248 7.37E-20 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_35705 de982431cf5571756ee983eb96a3beb4 253 Pfam PF07070 SpoOM protein 3 214 2.4E-76 T 12-10-2018 IPR009776 Sporulation stage 0, protein M AFR_25940 db862e707f9b9fedc77089ef91b74110 481 ProSitePatterns PS00674 AAA-protein family signature. 360 378 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFR_25940 db862e707f9b9fedc77089ef91b74110 481 SMART SM00382 251 392 2.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_25940 db862e707f9b9fedc77089ef91b74110 481 SUPERFAMILY SSF52540 216 474 7.88E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25940 db862e707f9b9fedc77089ef91b74110 481 Gene3D G3DSA:3.40.50.300 215 390 4.2E-56 T 12-10-2018 AFR_25940 db862e707f9b9fedc77089ef91b74110 481 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 255 389 1.4E-31 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_25940 db862e707f9b9fedc77089ef91b74110 481 Gene3D G3DSA:1.10.8.60 391 451 4.2E-56 T 12-10-2018 AFR_13190 4fef86a1269603cfd08ec23ecbb8035d 456 SUPERFAMILY SSF53850 31 453 1.26E-46 T 12-10-2018 AFR_13190 4fef86a1269603cfd08ec23ecbb8035d 456 Pfam PF01547 Bacterial extracellular solute-binding protein 75 362 5.3E-21 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_13190 4fef86a1269603cfd08ec23ecbb8035d 456 Gene3D G3DSA:3.40.190.10 55 453 3.2E-51 T 12-10-2018 AFR_14505 e2ec86c3b6eeaf57ca27024b558cf9ac 295 Gene3D G3DSA:3.30.450.180 111 284 1.4E-12 T 12-10-2018 AFR_14505 e2ec86c3b6eeaf57ca27024b558cf9ac 295 SMART SM00530 6 82 1.1E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_14505 e2ec86c3b6eeaf57ca27024b558cf9ac 295 Pfam PF13560 Helix-turn-helix domain 18 85 1.6E-13 T 12-10-2018 AFR_14505 e2ec86c3b6eeaf57ca27024b558cf9ac 295 SUPERFAMILY SSF47413 31 79 2.15E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_14350 5da7d9dd43681f73597b840c071e6283 411 Gene3D G3DSA:3.40.190.10 36 344 1.2E-90 T 12-10-2018 AFR_14350 5da7d9dd43681f73597b840c071e6283 411 SUPERFAMILY SSF53850 14 365 1.74E-52 T 12-10-2018 AFR_14350 5da7d9dd43681f73597b840c071e6283 411 Gene3D G3DSA:3.40.190.10 136 362 1.2E-90 T 12-10-2018 AFR_14350 5da7d9dd43681f73597b840c071e6283 411 Pfam PF01547 Bacterial extracellular solute-binding protein 34 319 4.3E-34 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_14350 5da7d9dd43681f73597b840c071e6283 411 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 130 147 - T 12-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 AFR_03510 a532f0e02828a97654775dbae19f8d52 308 Gene3D G3DSA:3.20.20.30 8 288 1.6E-62 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_03510 a532f0e02828a97654775dbae19f8d52 308 Pfam PF00296 Luciferase-like monooxygenase 17 233 7.4E-51 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_03510 a532f0e02828a97654775dbae19f8d52 308 SUPERFAMILY SSF51679 8 292 1.31E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_05020 3b115c7159e0360a76b444cdf741636d 386 SUPERFAMILY SSF55874 265 373 9.95E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_05020 3b115c7159e0360a76b444cdf741636d 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 373 2.3E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_05020 3b115c7159e0360a76b444cdf741636d 386 Gene3D G3DSA:3.30.565.10 247 379 1.5E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_14110 304ff3b3469793f4d6505617c6420231 185 Pfam PF07538 Clostridial hydrophobic W 57 92 7.2E-13 T 12-10-2018 IPR006637 Clostridial hydrophobic repeat AFR_14110 304ff3b3469793f4d6505617c6420231 185 Pfam PF07538 Clostridial hydrophobic W 104 138 1.6E-7 T 12-10-2018 IPR006637 Clostridial hydrophobic repeat AFR_14110 304ff3b3469793f4d6505617c6420231 185 Pfam PF07538 Clostridial hydrophobic W 149 185 2.6E-10 T 12-10-2018 IPR006637 Clostridial hydrophobic repeat AFR_14110 304ff3b3469793f4d6505617c6420231 185 SMART SM00728 56 104 0.0022 T 12-10-2018 IPR006637 Clostridial hydrophobic repeat AFR_14110 304ff3b3469793f4d6505617c6420231 185 SMART SM00728 148 185 0.53 T 12-10-2018 IPR006637 Clostridial hydrophobic repeat AFR_31140 4a68793fea2a169ee284ed7e89186a47 421 Gene3D G3DSA:3.40.190.10 146 410 2.4E-61 T 12-10-2018 AFR_31140 4a68793fea2a169ee284ed7e89186a47 421 Pfam PF13416 Bacterial extracellular solute-binding protein 50 352 3.9E-26 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_31140 4a68793fea2a169ee284ed7e89186a47 421 Gene3D G3DSA:3.40.190.10 52 350 2.4E-61 T 12-10-2018 AFR_31140 4a68793fea2a169ee284ed7e89186a47 421 SUPERFAMILY SSF53850 32 419 1.4E-48 T 12-10-2018 AFR_10655 f2e20060222fc2d5e5e48dfda4cf69e3 317 Pfam PF02628 Cytochrome oxidase assembly protein 13 185 1.1E-20 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 AFR_01350 adc31b65eefd4e71cf7df1162b807416 566 ProSitePatterns PS00211 ABC transporters family signature. 456 470 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_01350 adc31b65eefd4e71cf7df1162b807416 566 Gene3D G3DSA:3.40.50.300 308 560 3.9E-75 T 12-10-2018 AFR_01350 adc31b65eefd4e71cf7df1162b807416 566 Pfam PF00005 ABC transporter 335 487 2.2E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01350 adc31b65eefd4e71cf7df1162b807416 566 SUPERFAMILY SSF90123 2 285 3.14E-12 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFR_01350 adc31b65eefd4e71cf7df1162b807416 566 SMART SM00382 344 533 7.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01350 adc31b65eefd4e71cf7df1162b807416 566 SUPERFAMILY SSF52540 315 557 1.88E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_20285 c8c5aebb855546b35947668de8b1a543 390 Gene3D G3DSA:3.30.565.10 265 388 4.5E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20285 c8c5aebb855546b35947668de8b1a543 390 SUPERFAMILY SSF55874 274 377 8.66E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20285 c8c5aebb855546b35947668de8b1a543 390 Pfam PF07730 Histidine kinase 188 253 1.7E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_15295 93bfdbaa4caaeddd32e284905208bfa2 910 Gene3D G3DSA:3.20.20.80 410 747 5.8E-110 T 12-10-2018 AFR_15295 93bfdbaa4caaeddd32e284905208bfa2 910 SUPERFAMILY SSF51445 409 748 2.41E-98 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_15295 93bfdbaa4caaeddd32e284905208bfa2 910 Gene3D G3DSA:2.60.120.260 37 206 1.0E-54 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15295 93bfdbaa4caaeddd32e284905208bfa2 910 SUPERFAMILY SSF49785 6 203 1.55E-45 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_15295 93bfdbaa4caaeddd32e284905208bfa2 910 SUPERFAMILY SSF49303 366 412 1.24E-5 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily AFR_18390 b4389f38fc2a6c664c836407dd123f3d 308 SUPERFAMILY SSF55729 53 302 1.17E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_18390 b4389f38fc2a6c664c836407dd123f3d 308 Gene3D G3DSA:3.40.630.30 13 307 1.3E-30 T 12-10-2018 AFR_29030 1a450dfc2a7dea89cebaaea4d21308aa 317 Gene3D G3DSA:1.25.40.10 206 303 5.0E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_29030 1a450dfc2a7dea89cebaaea4d21308aa 317 SUPERFAMILY SSF48452 88 203 5.03E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_29030 1a450dfc2a7dea89cebaaea4d21308aa 317 SUPERFAMILY SSF48452 171 287 1.25E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_29030 1a450dfc2a7dea89cebaaea4d21308aa 317 Pfam PF13181 Tetratricopeptide repeat 172 201 0.11 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFR_29030 1a450dfc2a7dea89cebaaea4d21308aa 317 Gene3D G3DSA:1.25.40.10 49 202 3.4E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_22940 c3b5d7d896e6d3c03ade67056b258c4e 102 Gene3D G3DSA:3.10.450.50 2 94 3.1E-27 T 12-10-2018 AFR_22940 c3b5d7d896e6d3c03ade67056b258c4e 102 SUPERFAMILY SSF54427 10 91 1.17E-25 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_22940 c3b5d7d896e6d3c03ade67056b258c4e 102 Pfam PF07366 SnoaL-like polyketide cyclase 9 89 3.7E-24 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 AFR_00095 cc222bfca6d43120fb57a1d06d94f5fd 213 Gene3D G3DSA:3.40.30.10 1 204 1.2E-67 T 12-10-2018 AFR_00095 cc222bfca6d43120fb57a1d06d94f5fd 213 Pfam PF01323 DSBA-like thioredoxin domain 3 200 3.4E-39 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 AFR_00095 cc222bfca6d43120fb57a1d06d94f5fd 213 SUPERFAMILY SSF52833 1 206 8.77E-45 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_24890 21739c35f5343441b872692ecd7df5e5 210 Gene3D G3DSA:3.40.50.150 6 205 1.3E-17 T 12-10-2018 AFR_24890 21739c35f5343441b872692ecd7df5e5 210 Pfam PF13649 Methyltransferase domain 43 144 8.7E-7 T 12-10-2018 AFR_24890 21739c35f5343441b872692ecd7df5e5 210 SUPERFAMILY SSF53335 5 174 4.73E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_26880 a125d1691e570f856e574bf24f516122 682 Gene3D G3DSA:3.30.565.10 547 682 1.9E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26880 a125d1691e570f856e574bf24f516122 682 SUPERFAMILY SSF55874 579 673 1.44E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26880 a125d1691e570f856e574bf24f516122 682 Pfam PF07730 Histidine kinase 482 549 2.0E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_26880 a125d1691e570f856e574bf24f516122 682 Gene3D G3DSA:3.30.450.40 360 463 7.4E-7 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_26880 a125d1691e570f856e574bf24f516122 682 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 593 674 4.3E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_26880 a125d1691e570f856e574bf24f516122 682 SUPERFAMILY SSF55781 399 462 2.12E-7 T 12-10-2018 AFR_26880 a125d1691e570f856e574bf24f516122 682 SMART SM00387 586 676 0.0037 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_32250 a807d76c1dde40a41ed34233dbacf100 296 Gene3D G3DSA:3.40.1440.10 1 90 5.7E-21 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFR_32250 a807d76c1dde40a41ed34233dbacf100 296 SUPERFAMILY SSF82771 9 86 1.7E-14 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFR_32250 a807d76c1dde40a41ed34233dbacf100 296 SMART SM00465 8 89 7.0E-9 T 12-10-2018 IPR000305 GIY-YIG endonuclease AFR_32250 a807d76c1dde40a41ed34233dbacf100 296 Pfam PF01541 GIY-YIG catalytic domain 9 81 7.1E-5 T 12-10-2018 IPR000305 GIY-YIG endonuclease AFR_17305 44e086e1cc7688be9d06abcc2ba160d6 105 SUPERFAMILY SSF52091 15 100 4.71E-12 T 12-10-2018 IPR036513 STAS domain superfamily AFR_17305 44e086e1cc7688be9d06abcc2ba160d6 105 Gene3D G3DSA:3.30.750.24 11 102 6.3E-15 T 12-10-2018 IPR036513 STAS domain superfamily AFR_17305 44e086e1cc7688be9d06abcc2ba160d6 105 Pfam PF01740 STAS domain 12 98 6.5E-6 T 12-10-2018 IPR002645 STAS domain AFR_11705 6ae688244f106d15fab69a34195b0d13 533 Pfam PF06564 Cellulose biosynthesis protein BcsQ 252 393 3.2E-5 T 12-10-2018 IPR017746 Cellulose synthase operon protein BcsQ AFR_11705 6ae688244f106d15fab69a34195b0d13 533 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 251 425 7.1E-35 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 AFR_11705 6ae688244f106d15fab69a34195b0d13 533 SUPERFAMILY SSF52540 255 435 1.92E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_11705 6ae688244f106d15fab69a34195b0d13 533 Gene3D G3DSA:3.40.50.300 180 430 2.0E-52 T 12-10-2018 AFR_12290 0be5b3a75a50cda8fc8dfa170d6cee9c 129 SUPERFAMILY SSF51182 3 127 2.74E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_12290 0be5b3a75a50cda8fc8dfa170d6cee9c 129 Gene3D G3DSA:2.60.120.10 1 128 1.1E-32 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_12290 0be5b3a75a50cda8fc8dfa170d6cee9c 129 Pfam PF07883 Cupin domain 26 92 8.5E-17 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_13025 f5b879474f07d959fcd3d3d097253694 143 SMART SM00347 26 125 1.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_13025 f5b879474f07d959fcd3d3d097253694 143 Gene3D G3DSA:1.10.10.10 2 137 1.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_13025 f5b879474f07d959fcd3d3d097253694 143 SUPERFAMILY SSF46785 11 137 2.89E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13025 f5b879474f07d959fcd3d3d097253694 143 Pfam PF12802 MarR family 33 90 6.4E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_31605 7e4db0a712b02d6ee07f660c081e4562 524 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 8 519 6.5E-93 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 AFR_31605 7e4db0a712b02d6ee07f660c081e4562 524 Pfam PF00999 Sodium/hydrogen exchanger family 8 402 1.5E-48 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_10515 88de7c23444fb48e2c8ca49236c4cb5a 217 Pfam PF00753 Metallo-beta-lactamase superfamily 29 178 3.5E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_10515 88de7c23444fb48e2c8ca49236c4cb5a 217 SUPERFAMILY SSF56281 22 213 1.03E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_10515 88de7c23444fb48e2c8ca49236c4cb5a 217 Gene3D G3DSA:3.60.15.10 19 215 7.7E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_10515 88de7c23444fb48e2c8ca49236c4cb5a 217 SMART SM00849 32 196 3.1E-27 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_02375 963fc3bd7b32150d1ed79b703b82435f 133 SUPERFAMILY SSF50475 4 128 1.18E-23 T 12-10-2018 AFR_02375 963fc3bd7b32150d1ed79b703b82435f 133 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 128 4.8E-27 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_02375 963fc3bd7b32150d1ed79b703b82435f 133 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 89 6.4E-14 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_02375 963fc3bd7b32150d1ed79b703b82435f 133 Gene3D G3DSA:2.30.110.10 1 129 4.4E-29 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_16770 d16ade7644531ff10dd016fa9e1c34f7 147 SUPERFAMILY SSF46785 11 141 5.39E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_16770 d16ade7644531ff10dd016fa9e1c34f7 147 Pfam PF12802 MarR family 35 93 5.3E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_16770 d16ade7644531ff10dd016fa9e1c34f7 147 SMART SM00347 29 129 6.5E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_16770 d16ade7644531ff10dd016fa9e1c34f7 147 Gene3D G3DSA:1.10.10.10 3 145 5.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 3.8E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 PRINTS PR00732 Glycosyl hydrolase family 4 signature 72 88 3.8E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 3.8E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 3.8E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 PRINTS PR00732 Glycosyl hydrolase family 4 signature 93 106 3.8E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 3.8E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 PRINTS PR00732 Glycosyl hydrolase family 4 signature 3 18 3.8E-31 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 SUPERFAMILY SSF56327 168 428 3.02E-66 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 Pfam PF02056 Family 4 glycosyl hydrolase 4 184 1.0E-59 T 12-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 401 6.1E-60 T 12-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 SUPERFAMILY SSF51735 2 167 7.14E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_22550 5bb87c59b595201eda76f5baef2f3c05 430 Gene3D G3DSA:3.90.1820.20 1 424 6.3E-140 T 12-10-2018 AFR_42765 7368dd4b55a3e1e46431f587dc5ac15b 137 Gene3D G3DSA:3.30.1310.10 15 111 6.8E-10 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_42765 7368dd4b55a3e1e46431f587dc5ac15b 137 SUPERFAMILY SSF82607 20 105 7.46E-11 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_42765 7368dd4b55a3e1e46431f587dc5ac15b 137 Pfam PF02575 YbaB/EbfC DNA-binding family 20 103 3.4E-14 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFR_12120 e88f8ab2011895b1a6b767ba34b27351 951 Gene3D G3DSA:3.40.50.300 192 370 2.1E-9 T 12-10-2018 AFR_12120 e88f8ab2011895b1a6b767ba34b27351 951 Pfam PF13271 Domain of unknown function (DUF4062) 5 85 8.5E-19 T 12-10-2018 IPR025139 Domain of unknown function DUF4062 AFR_12120 e88f8ab2011895b1a6b767ba34b27351 951 SUPERFAMILY SSF52540 193 433 7.96E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_15415 ee4f03d5e33543f53adf3c030acee644 403 SUPERFAMILY SSF53474 37 400 5.23E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_15415 ee4f03d5e33543f53adf3c030acee644 403 Pfam PF07859 alpha/beta hydrolase fold 137 199 4.2E-7 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_14225 f831d1913418b31007f22d3b1cfb5c44 153 SUPERFAMILY SSF55729 4 137 1.92E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_14225 f831d1913418b31007f22d3b1cfb5c44 153 Pfam PF13508 Acetyltransferase (GNAT) domain 55 128 1.4E-11 T 12-10-2018 IPR000182 GNAT domain AFR_14225 f831d1913418b31007f22d3b1cfb5c44 153 Gene3D G3DSA:3.40.630.30 4 143 3.5E-27 T 12-10-2018 AFR_07755 c47126f4f3e8e3afc35a5cfc777eadb4 310 Gene3D G3DSA:3.10.560.10 166 230 1.3E-5 T 12-10-2018 AFR_07755 c47126f4f3e8e3afc35a5cfc777eadb4 310 SMART SM00278 258 277 0.049 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_07755 c47126f4f3e8e3afc35a5cfc777eadb4 310 SMART SM00278 288 307 250.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFR_07755 c47126f4f3e8e3afc35a5cfc777eadb4 310 Pfam PF10531 SLBB domain 171 222 8.6E-11 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_07755 c47126f4f3e8e3afc35a5cfc777eadb4 310 Gene3D G3DSA:1.10.150.320 234 309 2.7E-21 T 12-10-2018 AFR_07755 c47126f4f3e8e3afc35a5cfc777eadb4 310 Pfam PF12836 Helix-hairpin-helix motif 248 309 9.1E-21 T 12-10-2018 AFR_07755 c47126f4f3e8e3afc35a5cfc777eadb4 310 SUPERFAMILY SSF47781 244 310 1.67E-24 T 12-10-2018 IPR010994 RuvA domain 2-like AFR_12855 9cdd94b40b817a885ad05640d0454aac 100 SUPERFAMILY SSF54909 1 82 8.4E-8 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_12855 9cdd94b40b817a885ad05640d0454aac 100 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 4 77 6.0E-8 T 12-10-2018 IPR009799 EthD domain AFR_12855 9cdd94b40b817a885ad05640d0454aac 100 Gene3D G3DSA:3.30.70.100 1 84 2.7E-11 T 12-10-2018 AFR_10675 a49fce01758abb1b8f723568ac95ffdc 110 Pfam PF00355 Rieske [2Fe-2S] domain 5 90 6.5E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFR_10675 a49fce01758abb1b8f723568ac95ffdc 110 SUPERFAMILY SSF50022 1 104 1.09E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_10675 a49fce01758abb1b8f723568ac95ffdc 110 Gene3D G3DSA:2.102.10.10 2 107 2.6E-33 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFR_21880 aa45d297af0d2444b8b04144c991fdf8 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_21880 aa45d297af0d2444b8b04144c991fdf8 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_21880 aa45d297af0d2444b8b04144c991fdf8 187 SUPERFAMILY SSF46689 4 83 5.49E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21880 aa45d297af0d2444b8b04144c991fdf8 187 SUPERFAMILY SSF48498 82 185 5.48E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_21880 aa45d297af0d2444b8b04144c991fdf8 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.6E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_21880 aa45d297af0d2444b8b04144c991fdf8 187 Gene3D G3DSA:1.10.357.10 1 187 7.2E-66 T 12-10-2018 AFR_38345 7ad7d72a5ab46cd3b6d2e5011a752a27 120 Pfam PF02467 Transcription factor WhiB 19 68 4.7E-14 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain AFR_38345 7ad7d72a5ab46cd3b6d2e5011a752a27 120 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 82 16.285 T 12-10-2018 IPR003482 Transcription factor WhiB AFR_13710 8ab86bb184987042ecb173dc7063a839 230 Pfam PF06197 Protein of unknown function (DUF998) 20 210 8.7E-11 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_14360 1d4ecdfdecefabf316d25f8a1e246890 281 SUPERFAMILY SSF161098 12 281 1.4E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14360 1d4ecdfdecefabf316d25f8a1e246890 281 Gene3D G3DSA:1.10.3720.10 10 269 2.2E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14360 1d4ecdfdecefabf316d25f8a1e246890 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 276 7.2E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_07925 2dc8eebf8603e8689df3c5c91649cfd4 250 SUPERFAMILY SSF55729 71 242 1.1E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_07925 2dc8eebf8603e8689df3c5c91649cfd4 250 Pfam PF00583 Acetyltransferase (GNAT) family 157 236 7.6E-12 T 12-10-2018 IPR000182 GNAT domain AFR_07925 2dc8eebf8603e8689df3c5c91649cfd4 250 Gene3D G3DSA:3.40.630.30 14 245 4.9E-30 T 12-10-2018 AFR_35650 04c94eedad7a2815aa6ea8bc08655d05 141 Pfam PF02631 RecX family 1 111 1.4E-23 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 AFR_35650 04c94eedad7a2815aa6ea8bc08655d05 141 Gene3D G3DSA:1.10.10.10 16 61 2.8E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12095 bc87607628bde12c94bf71e68ad1b7fc 723 SUPERFAMILY SSF53474 351 465 5.07E-12 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12095 bc87607628bde12c94bf71e68ad1b7fc 723 Pfam PF02450 Lecithin:cholesterol acyltransferase 371 476 1.1E-5 T 12-10-2018 IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase GO:0006629|GO:0008374 AFR_12095 bc87607628bde12c94bf71e68ad1b7fc 723 Gene3D G3DSA:3.40.50.1820 353 491 1.3E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_06675 93f1b63028a9dd964b8108c9920fab83 408 Pfam PF13203 Putative metallopeptidase domain 6 263 1.0E-22 T 12-10-2018 IPR025154 Putative metallopeptidase domain AFR_06675 93f1b63028a9dd964b8108c9920fab83 408 SUPERFAMILY SSF53300 264 368 3.64E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_06675 93f1b63028a9dd964b8108c9920fab83 408 Pfam PF09967 VWA-like domain (DUF2201) 269 373 1.0E-13 T 12-10-2018 IPR018698 VWA-like domain AFR_31310 961c04f9517e1ca36b65e4c6a7b1e98f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 102 127 3.2E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_31310 961c04f9517e1ca36b65e4c6a7b1e98f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 3.2E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_31310 961c04f9517e1ca36b65e4c6a7b1e98f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 3.2E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_31310 961c04f9517e1ca36b65e4c6a7b1e98f 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 3.2E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_31310 961c04f9517e1ca36b65e4c6a7b1e98f 246 Pfam PF01061 ABC-2 type transporter 8 212 4.2E-23 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_31310 961c04f9517e1ca36b65e4c6a7b1e98f 246 PIRSF PIRSF006648 5 246 1.7E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_04900 0b759656d821e38f518bb9f34d9eb5a2 361 Gene3D G3DSA:3.40.50.2300 37 322 1.2E-94 T 12-10-2018 AFR_04900 0b759656d821e38f518bb9f34d9eb5a2 361 Gene3D G3DSA:3.40.50.2300 140 339 1.2E-94 T 12-10-2018 AFR_04900 0b759656d821e38f518bb9f34d9eb5a2 361 SUPERFAMILY SSF53822 36 334 2.16E-53 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_04900 0b759656d821e38f518bb9f34d9eb5a2 361 Pfam PF13407 Periplasmic binding protein domain 40 301 1.1E-53 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_27260 1dc58ab0cdec79e7c1cd03f38a0b6ff8 178 Pfam PF03713 Domain of unknown function (DUF305) 43 176 1.6E-29 T 12-10-2018 IPR005183 Domain of unknown function DUF305 AFR_27260 1dc58ab0cdec79e7c1cd03f38a0b6ff8 178 Gene3D G3DSA:1.20.1260.10 33 177 2.9E-33 T 12-10-2018 IPR012347 Ferritin-like AFR_02555 9a19c354a3e26c8f950302edfbeb4647 452 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 3 442 1.2E-83 T 12-10-2018 IPR007795 Type VII secretion system EccB AFR_02555 9a19c354a3e26c8f950302edfbeb4647 452 Gene3D G3DSA:2.40.50.900 71 147 3.7E-24 T 12-10-2018 AFR_02555 9a19c354a3e26c8f950302edfbeb4647 452 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 446 1.4E-78 T 12-10-2018 IPR007795 Type VII secretion system EccB AFR_36910 f6f403ea71b067e3710d35ec36b62466 801 SUPERFAMILY SSF51445 279 623 6.03E-102 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_36910 f6f403ea71b067e3710d35ec36b62466 801 Pfam PF00703 Glycosyl hydrolases family 2 196 282 1.8E-8 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 AFR_36910 f6f403ea71b067e3710d35ec36b62466 801 Gene3D G3DSA:2.60.120.260 8 183 2.8E-58 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_36910 f6f403ea71b067e3710d35ec36b62466 801 Gene3D G3DSA:3.20.20.80 282 621 2.0E-115 T 12-10-2018 AFR_36910 f6f403ea71b067e3710d35ec36b62466 801 Gene3D G3DSA:2.60.40.10 184 281 4.9E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_36910 f6f403ea71b067e3710d35ec36b62466 801 SUPERFAMILY SSF49785 4 180 1.84E-48 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_36910 f6f403ea71b067e3710d35ec36b62466 801 SUPERFAMILY SSF49303 184 282 6.62E-19 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily AFR_32255 cbb8199a11b80f7dcfa26f34737c5539 142 Gene3D G3DSA:3.40.630.30 15 128 7.2E-20 T 12-10-2018 AFR_32255 cbb8199a11b80f7dcfa26f34737c5539 142 Pfam PF00583 Acetyltransferase (GNAT) family 36 121 4.3E-13 T 12-10-2018 IPR000182 GNAT domain AFR_32255 cbb8199a11b80f7dcfa26f34737c5539 142 SUPERFAMILY SSF55729 33 124 4.9E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_16005 e1a939365b0663b2b5059291f7c09386 221 SUPERFAMILY SSF88713 27 171 2.0E-22 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_16005 e1a939365b0663b2b5059291f7c09386 221 Pfam PF01522 Polysaccharide deacetylase 45 166 1.4E-18 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_16005 e1a939365b0663b2b5059291f7c09386 221 Gene3D G3DSA:3.20.20.370 1 199 2.3E-26 T 12-10-2018 AFR_01775 bd90fbb47b711a27c33b4412f6a11b09 97 Pfam PF06013 Proteins of 100 residues with WXG 6 89 9.6E-17 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_01775 bd90fbb47b711a27c33b4412f6a11b09 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 6 92 1.4E-19 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like AFR_01775 bd90fbb47b711a27c33b4412f6a11b09 97 Gene3D G3DSA:1.10.287.1060 2 97 2.3E-22 T 12-10-2018 AFR_01775 bd90fbb47b711a27c33b4412f6a11b09 97 SUPERFAMILY SSF140453 5 96 4.84E-20 T 12-10-2018 IPR036689 ESAT-6-like superfamily AFR_01310 4b69fd5b5922785b11f121565a0d81b4 124 Gene3D G3DSA:3.10.180.10 3 122 4.7E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_01310 4b69fd5b5922785b11f121565a0d81b4 124 SUPERFAMILY SSF54593 4 122 3.3E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21840 46dce60c29cf2fbc47169fdde91e53d9 249 Gene3D G3DSA:3.90.1200.10 106 202 2.5E-9 T 12-10-2018 AFR_21840 46dce60c29cf2fbc47169fdde91e53d9 249 Pfam PF01636 Phosphotransferase enzyme family 111 186 2.5E-8 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_21840 46dce60c29cf2fbc47169fdde91e53d9 249 SUPERFAMILY SSF56112 25 194 1.9E-23 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_25590 fdca3b78ce80265daf242b91434cb663 1998 SUPERFAMILY SSF48452 1836 1948 2.72E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_25590 fdca3b78ce80265daf242b91434cb663 1998 Gene3D G3DSA:1.25.40.10 1823 1965 6.7E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_41905 9997ce653b1c11bf3ecf23016185ad60 258 Gene3D G3DSA:2.70.70.10 43 241 1.2E-18 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_41905 9997ce653b1c11bf3ecf23016185ad60 258 Pfam PF01551 Peptidase family M23 113 210 7.6E-14 T 12-10-2018 IPR016047 Peptidase M23 AFR_41905 9997ce653b1c11bf3ecf23016185ad60 258 SUPERFAMILY SSF51261 107 209 1.41E-16 T 12-10-2018 IPR011055 Duplicated hybrid motif AFR_25035 45e929efaaf8caa65372b81d58d363ec 264 SUPERFAMILY SSF88713 24 194 5.56E-31 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_25035 45e929efaaf8caa65372b81d58d363ec 264 Gene3D G3DSA:3.20.20.370 3 231 1.3E-47 T 12-10-2018 AFR_25035 45e929efaaf8caa65372b81d58d363ec 264 Pfam PF01522 Polysaccharide deacetylase 60 192 9.5E-25 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_41995 2d1a3d2eba5eb67755d37882b8a0dc4f 545 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 261 527 4.7E-60 T 12-10-2018 IPR018763 Protein of unknown function DUF2334 AFR_24355 6fef2d9e7a9ed71bfe41b90bb006196d 420 SUPERFAMILY SSF103473 14 407 2.35E-36 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_24355 6fef2d9e7a9ed71bfe41b90bb006196d 420 Pfam PF05977 Transmembrane secretion effector 7 401 1.3E-35 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_24355 6fef2d9e7a9ed71bfe41b90bb006196d 420 Gene3D G3DSA:1.20.1250.20 15 394 1.3E-27 T 12-10-2018 AFR_17560 33641bb533919a0b879b64d2fcdb0c71 262 SMART SM00530 15 70 2.4E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_17560 33641bb533919a0b879b64d2fcdb0c71 262 SUPERFAMILY SSF51182 66 177 5.84E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_17560 33641bb533919a0b879b64d2fcdb0c71 262 Pfam PF01381 Helix-turn-helix 16 70 7.9E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_17560 33641bb533919a0b879b64d2fcdb0c71 262 Pfam PF07883 Cupin domain 118 177 3.1E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_17560 33641bb533919a0b879b64d2fcdb0c71 262 Gene3D G3DSA:2.60.120.10 86 212 1.3E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_17560 33641bb533919a0b879b64d2fcdb0c71 262 SUPERFAMILY SSF47413 6 75 2.67E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_17560 33641bb533919a0b879b64d2fcdb0c71 262 Gene3D G3DSA:1.10.260.40 6 77 3.1E-17 T 12-10-2018 AFR_15920 72272d7665ee12edda56730671d97e54 415 Pfam PF07690 Major Facilitator Superfamily 265 411 5.5E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_15920 72272d7665ee12edda56730671d97e54 415 Pfam PF07690 Major Facilitator Superfamily 33 242 7.2E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_15920 72272d7665ee12edda56730671d97e54 415 Gene3D G3DSA:1.20.1250.20 19 217 7.2E-15 T 12-10-2018 AFR_15920 72272d7665ee12edda56730671d97e54 415 Gene3D G3DSA:1.20.1250.20 232 413 3.4E-16 T 12-10-2018 AFR_15920 72272d7665ee12edda56730671d97e54 415 SUPERFAMILY SSF103473 27 407 5.62E-40 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_25640 9768289f29222013bd4a350ee1c4fe9e 311 Pfam PF09471 IgA Peptidase M64 62 301 1.5E-54 T 12-10-2018 IPR019026 Peptidase M64, IgA AFR_25640 9768289f29222013bd4a350ee1c4fe9e 311 Gene3D G3DSA:3.40.390.10 56 307 1.3E-58 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 AFR_29860 f17163215781f7d3397bc474dd7c35a2 202 Pfam PF02698 DUF218 domain 8 153 3.0E-15 T 12-10-2018 IPR003848 Domain of unknown function DUF218 AFR_21910 948d86ae36f275061aa22fdce351238e 409 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 7 392 2.9E-108 T 12-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 AFR_21910 948d86ae36f275061aa22fdce351238e 409 SUPERFAMILY SSF51556 7 399 5.67E-100 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_21910 948d86ae36f275061aa22fdce351238e 409 Gene3D G3DSA:3.20.20.140 2 274 4.5E-101 T 12-10-2018 AFR_21910 948d86ae36f275061aa22fdce351238e 409 Gene3D G3DSA:3.20.20.140 299 407 5.5E-34 T 12-10-2018 AFR_06360 bed6a068509fe6909dbd34043b555b1c 248 Pfam PF12706 Beta-lactamase superfamily domain 30 214 9.1E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_06360 bed6a068509fe6909dbd34043b555b1c 248 SMART SM00849 18 196 5.2E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_06360 bed6a068509fe6909dbd34043b555b1c 248 SUPERFAMILY SSF56281 1 248 6.16E-53 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_06360 bed6a068509fe6909dbd34043b555b1c 248 Gene3D G3DSA:3.60.15.10 1 248 2.4E-72 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_28890 4baab392489d2177be5525da4fdf91a4 302 Gene3D G3DSA:3.40.50.1820 10 283 3.2E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28890 4baab392489d2177be5525da4fdf91a4 302 Pfam PF05448 Acetyl xylan esterase (AXE1) 86 131 1.7E-4 T 12-10-2018 IPR008391 Acetyl xylan esterase AFR_28890 4baab392489d2177be5525da4fdf91a4 302 SUPERFAMILY SSF53474 3 302 2.65E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28890 4baab392489d2177be5525da4fdf91a4 302 Gene3D G3DSA:1.10.10.800 138 226 3.2E-69 T 12-10-2018 AFR_16065 79c8d755541dbfb2d168964db4a2a02f 216 SUPERFAMILY SSF48498 90 215 3.71E-33 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_16065 79c8d755541dbfb2d168964db4a2a02f 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_16065 79c8d755541dbfb2d168964db4a2a02f 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_16065 79c8d755541dbfb2d168964db4a2a02f 216 SUPERFAMILY SSF46689 12 93 4.62E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_16065 79c8d755541dbfb2d168964db4a2a02f 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.5E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_16065 79c8d755541dbfb2d168964db4a2a02f 216 Gene3D G3DSA:1.10.357.10 20 216 1.2E-63 T 12-10-2018 AFR_17975 35d47e9735e25d464facc75c0105eb6b 188 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 110 177 1.0E-14 T 12-10-2018 IPR018656 Domain of unknown function DUF2087 AFR_17975 35d47e9735e25d464facc75c0105eb6b 188 SUPERFAMILY SSF46785 5 85 6.06E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_17975 35d47e9735e25d464facc75c0105eb6b 188 Gene3D G3DSA:1.10.10.10 2 104 2.6E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_39380 d8ffb9fbbd51ec73e31c67c7d1db85fb 194 Pfam PF03551 Transcriptional regulator PadR-like family 3 79 3.0E-12 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_39380 d8ffb9fbbd51ec73e31c67c7d1db85fb 194 SUPERFAMILY SSF46785 2 172 2.61E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_39380 d8ffb9fbbd51ec73e31c67c7d1db85fb 194 Gene3D G3DSA:1.10.10.10 1 85 4.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_12775 1cc1fa1636065eea278afd776bb7cc05 279 Pfam PF13460 NAD(P)H-binding 7 178 2.1E-21 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_12775 1cc1fa1636065eea278afd776bb7cc05 279 SUPERFAMILY SSF51735 2 268 1.67E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12775 1cc1fa1636065eea278afd776bb7cc05 279 Gene3D G3DSA:3.40.50.720 2 279 8.5E-60 T 12-10-2018 AFR_02925 89421c8ac68e2f6fc584bbb03de0fdb0 196 Pfam PF01169 Uncharacterized protein family UPF0016 113 183 4.3E-22 T 12-10-2018 IPR001727 Gdt1 family AFR_02925 89421c8ac68e2f6fc584bbb03de0fdb0 196 Pfam PF01169 Uncharacterized protein family UPF0016 11 83 1.3E-20 T 12-10-2018 IPR001727 Gdt1 family AFR_25010 ed01d905bbfc66f48f133ddf0fc05ba2 457 SUPERFAMILY SSF53448 137 375 1.97E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_25010 ed01d905bbfc66f48f133ddf0fc05ba2 457 Gene3D G3DSA:3.90.550.10 133 371 1.5E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_25010 ed01d905bbfc66f48f133ddf0fc05ba2 457 Pfam PF00535 Glycosyl transferase family 2 144 283 1.4E-25 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PIRSF PIRSF000126 1 258 3.4E-62 T 12-10-2018 AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 Gene3D G3DSA:3.40.50.720 6 235 4.8E-55 T 12-10-2018 AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 Pfam PF00106 short chain dehydrogenase 10 193 2.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.8E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.8E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.8E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.8E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_22140 9e76b0655d02b6710c72b8e4c193bef1 259 SUPERFAMILY SSF51735 5 224 1.83E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_08005 be6024e18fee631aaa75ff49d926d442 185 Gene3D G3DSA:3.40.50.1240 1 176 9.6E-28 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_08005 be6024e18fee631aaa75ff49d926d442 185 SUPERFAMILY SSF53254 2 175 3.53E-25 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_08005 be6024e18fee631aaa75ff49d926d442 185 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 53 3.6E-10 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_08005 be6024e18fee631aaa75ff49d926d442 185 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 98 165 1.2E-5 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_33100 a06caaf6d760c3807aa72729fd815b4a 309 Gene3D G3DSA:3.20.20.100 1 309 2.1E-69 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_33100 a06caaf6d760c3807aa72729fd815b4a 309 Pfam PF00248 Aldo/keto reductase family 3 308 4.6E-48 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_33100 a06caaf6d760c3807aa72729fd815b4a 309 SUPERFAMILY SSF51430 1 308 5.24E-64 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_07335 8f17cef377e13319387c70d0464f936c 272 Pfam PF02104 SURF1 family 20 229 1.1E-30 T 12-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFR_39460 acb3f690573d0cf1ece2725a0c0c6f05 523 Gene3D G3DSA:3.20.20.240 1 523 1.1E-227 T 12-10-2018 AFR_39460 acb3f690573d0cf1ece2725a0c0c6f05 523 SUPERFAMILY SSF51703 4 517 1.39E-203 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_39460 acb3f690573d0cf1ece2725a0c0c6f05 523 Pfam PF01642 Methylmalonyl-CoA mutase 4 515 9.8E-219 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_39460 acb3f690573d0cf1ece2725a0c0c6f05 523 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 3 518 7.2E-233 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_15890 08ebacea47c0d0d5a79ed71ad3a1b056 202 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 115 149 4.3E-6 T 12-10-2018 IPR001451 Hexapeptide repeat AFR_15890 08ebacea47c0d0d5a79ed71ad3a1b056 202 SUPERFAMILY SSF51161 7 168 2.13E-41 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFR_15890 08ebacea47c0d0d5a79ed71ad3a1b056 202 Gene3D G3DSA:2.160.10.10 4 165 7.1E-41 T 12-10-2018 AFR_15890 08ebacea47c0d0d5a79ed71ad3a1b056 202 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 39 71 8.7E-10 T 12-10-2018 IPR001451 Hexapeptide repeat AFR_39580 12863ac52e3fe1a76ba5293aa51cd680 430 Pfam PF02653 Branched-chain amino acid transport system / permease component 126 402 3.1E-42 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_32185 f72ceba91b85def8558edd407c83e3ac 380 SUPERFAMILY SSF103481 43 134 2.22E-10 T 12-10-2018 AFR_32185 f72ceba91b85def8558edd407c83e3ac 380 SUPERFAMILY SSF103481 177 275 4.97E-15 T 12-10-2018 AFR_32185 f72ceba91b85def8558edd407c83e3ac 380 Pfam PF00892 EamA-like transporter family 143 275 8.7E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_32185 f72ceba91b85def8558edd407c83e3ac 380 Pfam PF00892 EamA-like transporter family 7 132 1.0E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_06780 f6c37ad3050644f016f72c8f9671682c 143 Gene3D G3DSA:3.40.50.2300 2 140 2.3E-35 T 12-10-2018 AFR_06780 f6c37ad3050644f016f72c8f9671682c 143 SUPERFAMILY SSF52172 3 133 3.56E-34 T 12-10-2018 IPR011006 CheY-like superfamily AFR_06780 f6c37ad3050644f016f72c8f9671682c 143 SMART SM00448 4 126 3.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_06780 f6c37ad3050644f016f72c8f9671682c 143 Pfam PF00072 Response regulator receiver domain 6 126 7.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_24255 411cf4acefe50bc074fe77cbda78f812 424 Gene3D G3DSA:3.90.920.30 148 422 2.9E-81 T 12-10-2018 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 Gene3D G3DSA:3.40.50.970 403 619 1.8E-93 T 12-10-2018 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 Gene3D G3DSA:3.40.50.920 620 808 3.1E-67 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 ProSitePatterns PS60002 Phosphoketolase signature 1. 159 165 - T 12-10-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 Gene3D G3DSA:3.40.50.970 14 402 2.3E-162 T 12-10-2018 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 Pfam PF09363 XFP C-terminal domain 600 801 7.4E-80 T 12-10-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 PIRSF PIRSF017245 5 804 0.0 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 SUPERFAMILY SSF52518 393 602 3.3E-24 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 415 589 6.3E-81 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 ProSitePatterns PS60003 Phosphoketolase signature 2. 172 190 - T 12-10-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 SUPERFAMILY SSF52518 25 384 3.37E-62 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFR_22880 fdb81db6116ab3bace8c0674182b8e02 809 Pfam PF09364 XFP N-terminal domain 24 400 5.1E-169 T 12-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal AFR_00100 ba8cfcf568af58e51bafcfc1715ee3e9 138 SUPERFAMILY SSF82649 2 135 1.2E-23 T 12-10-2018 AFR_00100 ba8cfcf568af58e51bafcfc1715ee3e9 138 Gene3D G3DSA:3.90.1010.10 1 138 6.8E-46 T 12-10-2018 AFR_00100 ba8cfcf568af58e51bafcfc1715ee3e9 138 Pfam PF02657 Fe-S metabolism associated domain 11 133 1.0E-22 T 12-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like AFR_20515 908fea9db7ab330b4f3ff6252d4529e4 279 SUPERFAMILY SSF161098 13 266 8.32E-50 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20515 908fea9db7ab330b4f3ff6252d4529e4 279 Gene3D G3DSA:1.10.3720.10 5 263 1.3E-44 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20515 908fea9db7ab330b4f3ff6252d4529e4 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 263 6.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_15605 5cf8462938b7625e8fa50c15eecd547c 286 Pfam PF00106 short chain dehydrogenase 9 195 5.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15605 5cf8462938b7625e8fa50c15eecd547c 286 Gene3D G3DSA:3.40.50.720 1 285 3.1E-72 T 12-10-2018 AFR_15605 5cf8462938b7625e8fa50c15eecd547c 286 SUPERFAMILY SSF51735 1 249 1.44E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_15605 5cf8462938b7625e8fa50c15eecd547c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15605 5cf8462938b7625e8fa50c15eecd547c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_15605 5cf8462938b7625e8fa50c15eecd547c 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_03815 6e0d929a4daeb774bc16d0d40547e01b 119 Gene3D G3DSA:3.10.450.50 11 117 2.0E-20 T 12-10-2018 AFR_03815 6e0d929a4daeb774bc16d0d40547e01b 119 Pfam PF12680 SnoaL-like domain 17 86 8.5E-8 T 12-10-2018 IPR037401 SnoaL-like domain AFR_03815 6e0d929a4daeb774bc16d0d40547e01b 119 SUPERFAMILY SSF54427 8 113 5.79E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_21950 3f518552da10ed212c5e2d14a601224c 696 Pfam PF05547 Immune inhibitor A peptidase M6 487 604 1.8E-17 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_05140 55a3263d785c6667076267a847ec0c58 404 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 394 2.7E-68 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFR_05140 55a3263d785c6667076267a847ec0c58 404 PIRSF PIRSF000108 1 404 2.0E-222 T 12-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AFR_05140 55a3263d785c6667076267a847ec0c58 404 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFR_05140 55a3263d785c6667076267a847ec0c58 404 Gene3D G3DSA:3.40.718.10 1 404 1.8E-216 T 12-10-2018 AFR_05140 55a3263d785c6667076267a847ec0c58 404 SUPERFAMILY SSF53659 1 403 3.84E-154 T 12-10-2018 AFR_05140 55a3263d785c6667076267a847ec0c58 404 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 403 2.8E-211 T 12-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AFR_05140 55a3263d785c6667076267a847ec0c58 404 SMART SM01329 9 395 1.8E-132 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFR_21655 5b841b11a51ce7f50d1bb883d826d296 106 SUPERFAMILY SSF103481 5 104 4.05E-21 T 12-10-2018 AFR_21655 5b841b11a51ce7f50d1bb883d826d296 106 Gene3D G3DSA:1.10.3730.20 1 106 1.9E-37 T 12-10-2018 AFR_21655 5b841b11a51ce7f50d1bb883d826d296 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.2E-31 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 SUPERFAMILY SSF56655 4 262 7.98E-74 T 12-10-2018 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 5.1E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 5.1E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 5.1E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 5.1E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 Gene3D G3DSA:3.30.540.10 2 143 2.4E-38 T 12-10-2018 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 2.6E-89 T 12-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 Gene3D G3DSA:3.40.190.80 150 263 5.2E-23 T 12-10-2018 AFR_38150 bc7444a02e0b194a5b85c3a3b9afef32 267 Pfam PF00459 Inositol monophosphatase family 11 261 5.9E-52 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_05695 54f8503d81aefbbcbfb6de89e0175a16 434 Pfam PF01590 GAF domain 118 212 5.2E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_05695 54f8503d81aefbbcbfb6de89e0175a16 434 Gene3D G3DSA:3.30.450.40 30 215 2.1E-49 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_03485 c8c6c3976010f07d50dea14c5208646c 626 SUPERFAMILY SSF55486 407 502 8.35E-10 T 12-10-2018 AFR_03485 c8c6c3976010f07d50dea14c5208646c 626 Gene3D G3DSA:3.40.390.10 380 530 4.9E-8 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 AFR_28545 f9885782ab4d7aea5ab53f0522fa8a51 153 SUPERFAMILY SSF51182 17 124 3.91E-27 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_28545 f9885782ab4d7aea5ab53f0522fa8a51 153 Pfam PF07883 Cupin domain 39 108 4.6E-21 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_28545 f9885782ab4d7aea5ab53f0522fa8a51 153 Gene3D G3DSA:2.60.120.10 2 152 1.9E-35 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_33965 746bd4c4f3e9ee8aeb687836c3cc6764 252 PIRSF PIRSF036525 1 252 1.5E-107 T 12-10-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 AFR_33965 746bd4c4f3e9ee8aeb687836c3cc6764 252 Gene3D G3DSA:3.30.950.10 143 252 1.0E-46 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFR_33965 746bd4c4f3e9ee8aeb687836c3cc6764 252 SUPERFAMILY SSF53790 2 249 2.49E-37 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFR_33965 746bd4c4f3e9ee8aeb687836c3cc6764 252 Gene3D G3DSA:3.40.1010.10 1 142 1.5E-40 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFR_33965 746bd4c4f3e9ee8aeb687836c3cc6764 252 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 2 249 2.1E-104 T 12-10-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 AFR_33965 746bd4c4f3e9ee8aeb687836c3cc6764 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 223 2.5E-32 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFR_29705 37d20bbaa11cf151b5d380843d2cc1f7 369 Gene3D G3DSA:3.30.950.30 2 117 1.4E-10 T 12-10-2018 IPR038461 Schlafen, AAA domain superfamily AFR_29705 37d20bbaa11cf151b5d380843d2cc1f7 369 Pfam PF04326 Putative DNA-binding domain 6 105 3.6E-6 T 12-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 SUPERFAMILY SSF51735 6 251 7.0E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 3.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 3.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 Pfam PF00106 short chain dehydrogenase 9 206 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_32200 2443427b65ce4469f6639f13135dcb8a 306 Gene3D G3DSA:3.40.50.720 1 301 1.4E-73 T 12-10-2018 AFR_12560 47a65dc7d9666c5c6819f16c3b4f4ce7 246 Pfam PF01061 ABC-2 type transporter 6 211 4.6E-23 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_12560 47a65dc7d9666c5c6819f16c3b4f4ce7 246 PIRSF PIRSF006648 1 245 3.5E-19 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_12560 47a65dc7d9666c5c6819f16c3b4f4ce7 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 3.3E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_12560 47a65dc7d9666c5c6819f16c3b4f4ce7 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 98 123 3.3E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_12560 47a65dc7d9666c5c6819f16c3b4f4ce7 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 3.3E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_21035 eecce1ff44d5930862222c697a68a83b 540 Pfam PF02638 Glycosyl hydrolase-like 10 66 389 4.5E-82 T 12-10-2018 IPR003790 Glycosyl hydrolase-like 10 AFR_21035 eecce1ff44d5930862222c697a68a83b 540 SUPERFAMILY SSF51445 121 367 1.12E-20 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_21035 eecce1ff44d5930862222c697a68a83b 540 Gene3D G3DSA:3.20.20.70 118 291 2.8E-6 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_33815 2b4d3f251e2e15291b4bfaadda5db80f 213 Gene3D G3DSA:3.40.50.720 1 213 3.3E-56 T 12-10-2018 AFR_33815 2b4d3f251e2e15291b4bfaadda5db80f 213 SUPERFAMILY SSF51735 1 201 1.58E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_33815 2b4d3f251e2e15291b4bfaadda5db80f 213 Pfam PF13460 NAD(P)H-binding 7 190 3.8E-46 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_42290 0776292fc441565067a2c175ed4f4bad 525 SUPERFAMILY SSF52540 1 286 3.43E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42290 0776292fc441565067a2c175ed4f4bad 525 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 175 279 7.9E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFR_42290 0776292fc441565067a2c175ed4f4bad 525 Gene3D G3DSA:3.40.50.300 1 300 3.2E-15 T 12-10-2018 AFR_42290 0776292fc441565067a2c175ed4f4bad 525 Pfam PF13175 AAA ATPase domain 1 52 1.9E-12 T 12-10-2018 AFR_35730 755db2914275490761b520c9932e6535 226 Gene3D G3DSA:2.40.260.10 75 225 1.2E-27 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_35730 755db2914275490761b520c9932e6535 226 SUPERFAMILY SSF63817 81 223 3.4E-17 T 12-10-2018 IPR023365 Sortase domain superfamily AFR_35730 755db2914275490761b520c9932e6535 226 Pfam PF04203 Sortase family 89 224 1.8E-18 T 12-10-2018 IPR005754 Sortase family AFR_12335 585c8da1ab0a54773de8fe366979d2f6 136 Pfam PF12680 SnoaL-like domain 6 104 2.2E-14 T 12-10-2018 IPR037401 SnoaL-like domain AFR_12335 585c8da1ab0a54773de8fe366979d2f6 136 Gene3D G3DSA:3.10.450.50 1 110 3.6E-19 T 12-10-2018 AFR_12335 585c8da1ab0a54773de8fe366979d2f6 136 SUPERFAMILY SSF54427 4 109 3.14E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_39025 d536be4a9d62888b7dda3ace538111a4 245 Gene3D G3DSA:3.40.50.880 26 212 3.1E-29 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_39025 d536be4a9d62888b7dda3ace538111a4 245 Pfam PF03575 Peptidase family S51 37 210 1.1E-28 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 AFR_39025 d536be4a9d62888b7dda3ace538111a4 245 SUPERFAMILY SSF52317 41 213 6.35E-22 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_02435 a9a7a8397f46fb1ab74eef1f3433fe59 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 325 1.8E-47 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_09440 a49893e8223579d6e3627ea94776f229 95 Gene3D G3DSA:3.30.70.920 2 74 1.6E-20 T 12-10-2018 AFR_09440 a49893e8223579d6e3627ea94776f229 95 SUPERFAMILY SSF54909 3 78 4.96E-19 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_09440 a49893e8223579d6e3627ea94776f229 95 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 2.5E-16 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFR_31790 29caed7cda3e654d7ca4c36aa7643f2f 288 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 9 230 2.7E-87 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c AFR_31790 29caed7cda3e654d7ca4c36aa7643f2f 288 SUPERFAMILY SSF51679 13 285 1.7E-57 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_31790 29caed7cda3e654d7ca4c36aa7643f2f 288 Pfam PF00296 Luciferase-like monooxygenase 23 229 1.1E-43 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_31790 29caed7cda3e654d7ca4c36aa7643f2f 288 Gene3D G3DSA:3.20.20.30 1 288 1.8E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_03245 cee1d90d7f0da13432fe76250d288860 110 SUPERFAMILY SSF54909 1 101 1.98E-28 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_03245 cee1d90d7f0da13432fe76250d288860 110 Pfam PF05336 L-rhamnose mutarotase 2 101 7.8E-27 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 AFR_03245 cee1d90d7f0da13432fe76250d288860 110 Gene3D G3DSA:3.30.70.100 1 94 8.0E-29 T 12-10-2018 AFR_22930 784e08405e894812fb6ade539eadb869 260 SUPERFAMILY SSF53474 1 245 2.58E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22930 784e08405e894812fb6ade539eadb869 260 Gene3D G3DSA:3.40.50.1820 1 247 3.1E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22930 784e08405e894812fb6ade539eadb869 260 Pfam PF12697 Alpha/beta hydrolase family 1 237 3.5E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_25070 380ef6141b83a5701d7cbbe4c887ffff 233 SUPERFAMILY SSF56281 2 223 5.11E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_25070 380ef6141b83a5701d7cbbe4c887ffff 233 Gene3D G3DSA:3.60.15.10 1 228 4.5E-50 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_25070 380ef6141b83a5701d7cbbe4c887ffff 233 Pfam PF00753 Metallo-beta-lactamase superfamily 13 206 1.6E-28 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_25070 380ef6141b83a5701d7cbbe4c887ffff 233 SMART SM00849 15 206 3.6E-28 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_20270 54acd7a153fe47f851ae5d557bf267fc 338 Pfam PF05117 Family of unknown function (DUF695) 212 332 5.5E-5 T 12-10-2018 IPR016097 Domain of unknown function DUF695 AFR_16000 2a807050cb7307ed2941a3ed1ad6a821 288 Pfam PF00535 Glycosyl transferase family 2 3 110 5.9E-13 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_16000 2a807050cb7307ed2941a3ed1ad6a821 288 Gene3D G3DSA:3.90.550.10 1 229 3.7E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16000 2a807050cb7307ed2941a3ed1ad6a821 288 SUPERFAMILY SSF53448 2 120 3.0E-19 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_15570 b5102752a02bda528d9d8d396c15589b 509 SUPERFAMILY SSF56801 112 458 4.69E-11 T 12-10-2018 AFR_15570 b5102752a02bda528d9d8d396c15589b 509 Gene3D G3DSA:3.40.50.12780 36 278 1.3E-21 T 12-10-2018 AFR_30145 d6f875d53cbfb87a9fdd6ae6d5bd9299 182 Pfam PF01899 Na+/H+ ion antiporter subunit 18 163 6.0E-31 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AFR_16855 4685ed4edbeb15b918237be91c0d3378 435 Gene3D G3DSA:3.40.190.10 26 434 2.4E-56 T 12-10-2018 AFR_16855 4685ed4edbeb15b918237be91c0d3378 435 Pfam PF01547 Bacterial extracellular solute-binding protein 43 343 4.5E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_16855 4685ed4edbeb15b918237be91c0d3378 435 SUPERFAMILY SSF53850 16 428 4.3E-59 T 12-10-2018 AFR_37905 9ff6956a0fdb8103d07374bd0babe77f 274 Pfam PF01734 Patatin-like phospholipase 8 176 3.5E-29 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFR_37905 9ff6956a0fdb8103d07374bd0babe77f 274 SUPERFAMILY SSF52151 3 189 1.29E-46 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_37905 9ff6956a0fdb8103d07374bd0babe77f 274 Gene3D G3DSA:3.40.1090.10 93 194 1.9E-13 T 12-10-2018 AFR_37905 9ff6956a0fdb8103d07374bd0babe77f 274 Gene3D G3DSA:3.40.1090.10 2 92 9.2E-17 T 12-10-2018 AFR_19685 3a81a45ec279dd87e57e349872e6e0d2 276 Pfam PF13460 NAD(P)H-binding 7 151 2.1E-15 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_19685 3a81a45ec279dd87e57e349872e6e0d2 276 SUPERFAMILY SSF51735 1 249 6.71E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_19685 3a81a45ec279dd87e57e349872e6e0d2 276 Gene3D G3DSA:3.40.50.720 2 273 5.0E-38 T 12-10-2018 AFR_35990 dcc9f6db8995230dbb30933893a5774b 222 Pfam PF02576 RimP N-terminal domain 48 124 2.5E-21 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal AFR_35990 dcc9f6db8995230dbb30933893a5774b 222 Pfam PF17384 RimP C-terminal SH3 domain 127 187 2.4E-8 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal AFR_35990 dcc9f6db8995230dbb30933893a5774b 222 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 42 187 21.493 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 AFR_35990 dcc9f6db8995230dbb30933893a5774b 222 SUPERFAMILY SSF75420 41 124 4.45E-19 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily AFR_35990 dcc9f6db8995230dbb30933893a5774b 222 Gene3D G3DSA:3.30.300.70 37 121 5.0E-18 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily AFR_20350 10a2708737f9561e43a2f3b1b3aa3911 211 Gene3D G3DSA:3.30.530.20 7 190 6.3E-36 T 12-10-2018 IPR023393 START-like domain superfamily AFR_20350 10a2708737f9561e43a2f3b1b3aa3911 211 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 37 141 4.9E-11 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_20350 10a2708737f9561e43a2f3b1b3aa3911 211 SUPERFAMILY SSF55961 30 150 1.46E-27 T 12-10-2018 AFR_15195 327d0f85be2565db2b2d436a08acb25f 488 SUPERFAMILY SSF69304 226 475 3.01E-5 T 12-10-2018 AFR_15195 327d0f85be2565db2b2d436a08acb25f 488 Pfam PF05787 Bacterial protein of unknown function (DUF839) 152 474 1.3E-49 T 12-10-2018 IPR008557 Protein of unknown function DUF839 AFR_15195 327d0f85be2565db2b2d436a08acb25f 488 Pfam PF05787 Bacterial protein of unknown function (DUF839) 50 148 1.2E-6 T 12-10-2018 IPR008557 Protein of unknown function DUF839 AFR_18695 1312f9df8e265b0a1b17c8a198a51df9 445 Gene3D G3DSA:1.20.1250.20 8 224 7.9E-60 T 12-10-2018 AFR_18695 1312f9df8e265b0a1b17c8a198a51df9 445 Pfam PF07690 Major Facilitator Superfamily 52 397 1.5E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_18695 1312f9df8e265b0a1b17c8a198a51df9 445 SUPERFAMILY SSF103473 22 439 2.75E-39 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_18695 1312f9df8e265b0a1b17c8a198a51df9 445 Gene3D G3DSA:1.20.1250.20 225 443 6.1E-67 T 12-10-2018 AFR_24745 f80df16f3aaddef82319813533757445 143 Gene3D G3DSA:3.30.530.20 15 143 1.2E-47 T 12-10-2018 IPR023393 START-like domain superfamily AFR_24745 f80df16f3aaddef82319813533757445 143 SUPERFAMILY SSF55961 18 143 9.35E-31 T 12-10-2018 AFR_24745 f80df16f3aaddef82319813533757445 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 21 142 2.9E-8 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_25315 5682135d363da15da426341e5a85af4e 316 SUPERFAMILY SSF51445 4 279 1.44E-16 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_25315 5682135d363da15da426341e5a85af4e 316 Gene3D G3DSA:3.20.20.80 6 313 1.2E-21 T 12-10-2018 AFR_08015 53e3023068b1910237bdfdd6c1545009 98 Pfam PF01910 Thiamine-binding protein 3 92 3.6E-29 T 12-10-2018 IPR002767 Thiamine-binding protein AFR_08015 53e3023068b1910237bdfdd6c1545009 98 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 94 1.4E-17 T 12-10-2018 IPR002767 Thiamine-binding protein AFR_08015 53e3023068b1910237bdfdd6c1545009 98 SUPERFAMILY SSF89957 1 95 4.71E-28 T 12-10-2018 IPR029756 MTH1187/YkoF-like AFR_08015 53e3023068b1910237bdfdd6c1545009 98 Gene3D G3DSA:3.30.70.930 1 96 1.5E-27 T 12-10-2018 IPR029756 MTH1187/YkoF-like AFR_04985 db554f445787aa6ecf672fa1e6c7031b 93 Pfam PF04024 PspC domain 10 68 3.8E-20 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal AFR_01275 41f93fd291ed79ebacaf4b465ab92043 835 Gene3D G3DSA:3.40.50.2000 626 796 2.0E-59 T 12-10-2018 AFR_01275 41f93fd291ed79ebacaf4b465ab92043 835 Pfam PF13439 Glycosyltransferase Family 4 465 628 4.9E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_01275 41f93fd291ed79ebacaf4b465ab92043 835 SUPERFAMILY SSF53756 458 815 2.09E-69 T 12-10-2018 AFR_01275 41f93fd291ed79ebacaf4b465ab92043 835 Pfam PF00534 Glycosyl transferases group 1 642 792 7.7E-27 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_01275 41f93fd291ed79ebacaf4b465ab92043 835 Gene3D G3DSA:3.40.50.2000 462 812 2.0E-59 T 12-10-2018 AFR_16760 af55c4345570000d79a1526a209b3fc0 325 Gene3D G3DSA:3.20.20.190 34 230 2.1E-34 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_16760 af55c4345570000d79a1526a209b3fc0 325 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 182 2.9E-25 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFR_16760 af55c4345570000d79a1526a209b3fc0 325 SUPERFAMILY SSF51695 37 283 3.56E-38 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_00660 54e0a7b2536ae016b0640fb00a2fd159 140 Pfam PF11349 Protein of unknown function (DUF3151) 7 137 1.7E-57 T 12-10-2018 IPR014487 Protein of unknown function DUF3151 AFR_00660 54e0a7b2536ae016b0640fb00a2fd159 140 PIRSF PIRSF017349 1 140 1.8E-53 T 12-10-2018 IPR014487 Protein of unknown function DUF3151 AFR_40995 257d1d26485f7042b3ee671ffce4a410 305 SUPERFAMILY SSF53448 1 218 6.0E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_40995 257d1d26485f7042b3ee671ffce4a410 305 Gene3D G3DSA:3.90.550.10 1 216 1.3E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_40995 257d1d26485f7042b3ee671ffce4a410 305 Pfam PF00535 Glycosyl transferase family 2 2 112 9.3E-23 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_26895 0a0bba4a851bf311ab55e64929470ac9 129 Pfam PF01890 Cobalamin synthesis G C-terminus 7 125 3.7E-31 T 12-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 AFR_26895 0a0bba4a851bf311ab55e64929470ac9 129 Gene3D G3DSA:3.30.420.180 1 129 1.3E-31 T 12-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AFR_26895 0a0bba4a851bf311ab55e64929470ac9 129 SUPERFAMILY SSF159664 6 127 4.45E-33 T 12-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AFR_07030 2bb3c836af9c889f104c66a20a99b458 456 Gene3D G3DSA:1.20.1250.20 1 424 2.0E-53 T 12-10-2018 AFR_07030 2bb3c836af9c889f104c66a20a99b458 456 PRINTS PR01035 Tetracycline resistance protein signature 10 26 2.0E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_07030 2bb3c836af9c889f104c66a20a99b458 456 PRINTS PR01035 Tetracycline resistance protein signature 153 173 2.0E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_07030 2bb3c836af9c889f104c66a20a99b458 456 PRINTS PR01035 Tetracycline resistance protein signature 95 116 2.0E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_07030 2bb3c836af9c889f104c66a20a99b458 456 PRINTS PR01035 Tetracycline resistance protein signature 125 147 2.0E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFR_07030 2bb3c836af9c889f104c66a20a99b458 456 Pfam PF07690 Major Facilitator Superfamily 13 382 3.0E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_07030 2bb3c836af9c889f104c66a20a99b458 456 SUPERFAMILY SSF103473 2 427 1.96E-49 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_20325 31adb343e013df9ba5c86855def075cf 245 Pfam PF04250 Protein of unknown function (DUF429) 5 220 1.1E-30 T 12-10-2018 IPR007362 Protein of unknown function DUF429 AFR_40900 38460429780d37c07c82959641c3c942 315 Gene3D G3DSA:3.40.630.30 5 315 7.4E-74 T 12-10-2018 AFR_40900 38460429780d37c07c82959641c3c942 315 SUPERFAMILY SSF55729 12 129 6.18E-12 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40900 38460429780d37c07c82959641c3c942 315 SUPERFAMILY SSF55729 203 311 2.74E-12 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40900 38460429780d37c07c82959641c3c942 315 Pfam PF00583 Acetyltransferase (GNAT) family 30 116 8.4E-8 T 12-10-2018 IPR000182 GNAT domain AFR_19795 dbd863470f4d1ed4e6fe046a584623b4 261 Gene3D G3DSA:2.120.10.30 2 260 2.0E-32 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_19795 dbd863470f4d1ed4e6fe046a584623b4 261 SUPERFAMILY SSF63829 3 256 1.83E-42 T 12-10-2018 AFR_19795 dbd863470f4d1ed4e6fe046a584623b4 261 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 10 228 2.6E-32 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region AFR_38800 a3c4536af49a0f0eded520121e6ddaec 480 Pfam PF01523 Putative modulator of DNA gyrase 23 327 3.5E-50 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFR_38800 a3c4536af49a0f0eded520121e6ddaec 480 SUPERFAMILY SSF111283 4 476 4.45E-85 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 AFR_38800 a3c4536af49a0f0eded520121e6ddaec 480 Gene3D G3DSA:3.30.2290.10 4 223 3.6E-17 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal AFR_11610 bc11d1752e6f737edfa6c7ef4d659275 184 Pfam PF04892 VanZ like family 42 157 4.3E-15 T 12-10-2018 IPR006976 VanZ-like AFR_34670 1833f38fbd2f2d16dfb370178d974702 440 SUPERFAMILY SSF55874 209 308 8.17E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34670 1833f38fbd2f2d16dfb370178d974702 440 Gene3D G3DSA:3.30.565.10 192 309 3.9E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34670 1833f38fbd2f2d16dfb370178d974702 440 Pfam PF07730 Histidine kinase 130 194 1.5E-10 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_02360 67f0f8e28bc4661e835530b379436da2 259 Pfam PF03640 Secreted repeat of unknown function 183 223 1.2E-16 T 12-10-2018 IPR005297 Lipoprotein repeat AFR_02360 67f0f8e28bc4661e835530b379436da2 259 Pfam PF03640 Secreted repeat of unknown function 125 162 2.2E-11 T 12-10-2018 IPR005297 Lipoprotein repeat AFR_12815 1547b1c574604b9d8b74c9a4b92171eb 356 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 3 304 2.3E-28 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFR_12815 1547b1c574604b9d8b74c9a4b92171eb 356 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 190 308 1.9E-16 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFR_33025 e2165985ddc327ace96c57541a75bf1e 501 Gene3D G3DSA:2.115.10.20 259 500 1.1E-58 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_33025 e2165985ddc327ace96c57541a75bf1e 501 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 273 497 8.6E-28 T 12-10-2018 IPR007184 Mannoside phosphorylase AFR_33025 e2165985ddc327ace96c57541a75bf1e 501 SUPERFAMILY SSF75005 277 490 3.06E-49 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_02220 4f32bdbab435a9b722ed00901a8a8583 205 Pfam PF00881 Nitroreductase family 7 174 2.3E-21 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFR_02220 4f32bdbab435a9b722ed00901a8a8583 205 SUPERFAMILY SSF55469 1 200 3.01E-39 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_02220 4f32bdbab435a9b722ed00901a8a8583 205 Gene3D G3DSA:3.40.109.10 4 203 3.2E-37 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_21450 9eeeb1621554e9ea1b1cfa7e8811c993 189 SUPERFAMILY SSF46689 7 79 5.64E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_21450 9eeeb1621554e9ea1b1cfa7e8811c993 189 Gene3D G3DSA:1.10.357.10 4 187 2.0E-26 T 12-10-2018 AFR_21450 9eeeb1621554e9ea1b1cfa7e8811c993 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_31810 31e0539411b9c61e4f797ea1727546e2 138 Gene3D G3DSA:3.30.565.10 3 131 2.3E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_31810 31e0539411b9c61e4f797ea1727546e2 138 Pfam PF13581 Histidine kinase-like ATPase domain 10 116 3.9E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_31810 31e0539411b9c61e4f797ea1727546e2 138 SUPERFAMILY SSF55874 32 125 1.3E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26655 0ca04f8c37604108633ddb76f75f1032 338 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 135 152 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFR_26655 0ca04f8c37604108633ddb76f75f1032 338 PRINTS PR00069 Aldo-keto reductase signature 135 152 7.5E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_26655 0ca04f8c37604108633ddb76f75f1032 338 PRINTS PR00069 Aldo-keto reductase signature 104 122 7.5E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFR_26655 0ca04f8c37604108633ddb76f75f1032 338 Pfam PF00248 Aldo/keto reductase family 16 311 1.1E-64 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_26655 0ca04f8c37604108633ddb76f75f1032 338 Gene3D G3DSA:3.20.20.100 1 327 4.8E-102 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_26655 0ca04f8c37604108633ddb76f75f1032 338 SUPERFAMILY SSF51430 1 311 6.81E-91 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_26185 2d89fc804304780760422330899cbbf5 247 SUPERFAMILY SSF55961 114 246 6.59E-6 T 12-10-2018 AFR_29775 64d2893f42936600d447637bca8824d9 121 Gene3D G3DSA:3.10.180.10 2 121 1.8E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_29775 64d2893f42936600d447637bca8824d9 121 SUPERFAMILY SSF54593 1 118 1.34E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_29775 64d2893f42936600d447637bca8824d9 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 116 1.5E-10 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_39400 532aeb2e4eef706dc61f9022a24f3097 290 Gene3D G3DSA:3.10.620.30 97 282 2.1E-45 T 12-10-2018 AFR_39400 532aeb2e4eef706dc61f9022a24f3097 290 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 11 89 4.8E-18 T 12-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal AFR_39400 532aeb2e4eef706dc61f9022a24f3097 290 SUPERFAMILY SSF54001 127 273 5.89E-37 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_39400 532aeb2e4eef706dc61f9022a24f3097 290 Pfam PF01841 Transglutaminase-like superfamily 136 243 2.2E-23 T 12-10-2018 IPR002931 Transglutaminase-like AFR_39400 532aeb2e4eef706dc61f9022a24f3097 290 SMART SM00460 178 245 2.2E-19 T 12-10-2018 IPR002931 Transglutaminase-like AFR_17115 d47855f1a3b0e0ebddb5ffe96a988560 208 Pfam PF09335 SNARE associated Golgi protein 39 163 4.3E-17 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 SMART SM00342 190 273 2.7E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 269 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 Pfam PF12833 Helix-turn-helix domain 196 274 3.0E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 Gene3D G3DSA:1.10.10.60 170 276 2.3E-30 T 12-10-2018 AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 SUPERFAMILY SSF46689 226 275 8.97E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 257 273 7.9E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 242 257 7.9E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFR_15460 98a4f2377ae8a3775be42cb5141e0c1c 276 SUPERFAMILY SSF46689 175 224 6.63E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_03220 a493276fafea6cc5079d0e4a4184507c 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 332 3.3E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_02305 26b2b6a9b5d15682643f1d4ad9982679 477 Pfam PF03663 Glycosyl hydrolase family 76 159 455 1.4E-44 T 12-10-2018 IPR005198 Glycoside hydrolase, family 76 AFR_02305 26b2b6a9b5d15682643f1d4ad9982679 477 Gene3D G3DSA:1.50.10.20 152 475 1.1E-75 T 12-10-2018 AFR_02305 26b2b6a9b5d15682643f1d4ad9982679 477 SUPERFAMILY SSF48208 170 436 1.42E-40 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_37525 11cbb3880bb6c22c9ccb20b4549f1489 223 Gene3D G3DSA:3.90.226.10 3 221 1.2E-51 T 12-10-2018 AFR_37525 11cbb3880bb6c22c9ccb20b4549f1489 223 SUPERFAMILY SSF52096 4 217 7.79E-41 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_37525 11cbb3880bb6c22c9ccb20b4549f1489 223 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 215 1.4E-24 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_10980 6d9efb9cac3aafc153c2b72164e367e7 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 30 54 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFR_10980 6d9efb9cac3aafc153c2b72164e367e7 312 SUPERFAMILY SSF53613 4 305 5.14E-62 T 12-10-2018 IPR029056 Ribokinase-like AFR_10980 6d9efb9cac3aafc153c2b72164e367e7 312 Gene3D G3DSA:3.40.1190.20 3 308 1.1E-70 T 12-10-2018 IPR029056 Ribokinase-like AFR_10980 6d9efb9cac3aafc153c2b72164e367e7 312 Pfam PF00294 pfkB family carbohydrate kinase 3 300 1.5E-49 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFR_18735 4f418873b2af9f8951760b1ef1fd3355 335 SMART SM00342 245 327 3.7E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_18735 4f418873b2af9f8951760b1ef1fd3355 335 SUPERFAMILY SSF46689 280 329 3.27E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_18735 4f418873b2af9f8951760b1ef1fd3355 335 Gene3D G3DSA:1.10.10.60 227 331 3.0E-19 T 12-10-2018 AFR_18735 4f418873b2af9f8951760b1ef1fd3355 335 Pfam PF12833 Helix-turn-helix domain 251 328 2.9E-14 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_18735 4f418873b2af9f8951760b1ef1fd3355 335 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 18 196 3.2E-35 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AFR_12175 101fcb18947350fbfd15f75056b04e8d 87 Pfam PF13586 Transposase DDE domain 1 81 1.3E-12 T 12-10-2018 IPR025668 Transposase DDE domain AFR_39700 6f42fcabcf0084ae47cf66344ec5e9ae 294 Gene3D G3DSA:3.30.540.10 26 171 2.2E-20 T 12-10-2018 AFR_39700 6f42fcabcf0084ae47cf66344ec5e9ae 294 SUPERFAMILY SSF56655 28 292 3.14E-45 T 12-10-2018 AFR_39700 6f42fcabcf0084ae47cf66344ec5e9ae 294 Gene3D G3DSA:3.40.190.80 178 293 8.7E-20 T 12-10-2018 AFR_39700 6f42fcabcf0084ae47cf66344ec5e9ae 294 Pfam PF00459 Inositol monophosphatase family 30 292 7.4E-26 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_39700 6f42fcabcf0084ae47cf66344ec5e9ae 294 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 113 125 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site AFR_09705 e38e078fc25af8016ef50551a1633d34 108 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 5 93 3.5E-20 T 12-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 AFR_11710 fd299f6a46733e406efdec9a9a8a5e59 420 Gene3D G3DSA:3.40.50.2000 208 380 3.0E-20 T 12-10-2018 AFR_11710 fd299f6a46733e406efdec9a9a8a5e59 420 Pfam PF13579 Glycosyl transferase 4-like domain 18 190 1.9E-22 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_11710 fd299f6a46733e406efdec9a9a8a5e59 420 Gene3D G3DSA:3.40.50.2000 1 207 9.9E-25 T 12-10-2018 AFR_11710 fd299f6a46733e406efdec9a9a8a5e59 420 SUPERFAMILY SSF53756 2 398 1.08E-50 T 12-10-2018 AFR_11710 fd299f6a46733e406efdec9a9a8a5e59 420 Pfam PF13692 Glycosyl transferases group 1 217 365 5.3E-11 T 12-10-2018 AFR_04075 32219e5e3c44393a46bb5723209c8496 100 Gene3D G3DSA:1.20.58.1000 13 100 5.2E-33 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily AFR_04075 32219e5e3c44393a46bb5723209c8496 100 Pfam PF02583 Metal-sensitive transcriptional repressor 16 95 1.8E-31 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 AFR_19245 9ff9f8284318fcc5256a390355c6a99d 119 SUPERFAMILY SSF52091 15 115 2.75E-24 T 12-10-2018 IPR036513 STAS domain superfamily AFR_19245 9ff9f8284318fcc5256a390355c6a99d 119 Pfam PF01740 STAS domain 15 109 2.8E-15 T 12-10-2018 IPR002645 STAS domain AFR_19245 9ff9f8284318fcc5256a390355c6a99d 119 Gene3D G3DSA:3.30.750.24 6 118 1.5E-27 T 12-10-2018 IPR036513 STAS domain superfamily AFR_13205 58271eda93acb1e2343e7e5ffb418549 293 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 94 269 3.2E-16 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_13205 58271eda93acb1e2343e7e5ffb418549 293 SUPERFAMILY SSF52266 88 280 8.7E-29 T 12-10-2018 AFR_13205 58271eda93acb1e2343e7e5ffb418549 293 Gene3D G3DSA:3.40.50.1110 78 281 2.0E-28 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_09515 ff66fefb304add26631a451e4efa942e 266 Gene3D G3DSA:3.40.50.300 9 247 4.8E-56 T 12-10-2018 AFR_09515 ff66fefb304add26631a451e4efa942e 266 Pfam PF00005 ABC transporter 44 177 1.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_09515 ff66fefb304add26631a451e4efa942e 266 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_09515 ff66fefb304add26631a451e4efa942e 266 SUPERFAMILY SSF52540 18 238 2.88E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_09515 ff66fefb304add26631a451e4efa942e 266 SMART SM00382 41 226 4.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_38265 1c8f5699ce249dac4e08826ebbce2b66 401 Pfam PF03741 Integral membrane protein TerC family 69 272 2.7E-47 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFR_38265 1c8f5699ce249dac4e08826ebbce2b66 401 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 318 2.0E-106 T 12-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 AFR_36575 df12f9c70ec5852c5d37ff9e98c44cd3 113 Gene3D G3DSA:3.20.170.20 1 112 1.5E-32 T 12-10-2018 AFR_36575 df12f9c70ec5852c5d37ff9e98c44cd3 113 SUPERFAMILY SSF56399 2 111 1.61E-25 T 12-10-2018 AFR_36575 df12f9c70ec5852c5d37ff9e98c44cd3 113 Pfam PF06108 Protein of unknown function (DUF952) 6 96 2.6E-25 T 12-10-2018 IPR009297 Protein of unknown function DUF952 AFR_06230 4ead37c4aed8ba632030f7a9ef56b1a1 129 Gene3D G3DSA:2.60.120.10 5 123 4.7E-37 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_06230 4ead37c4aed8ba632030f7a9ef56b1a1 129 Pfam PF07883 Cupin domain 30 98 1.0E-16 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_06230 4ead37c4aed8ba632030f7a9ef56b1a1 129 SUPERFAMILY SSF51182 6 113 5.94E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_20505 373915bf58379ab5881eb94acbc4f630 404 Gene3D G3DSA:1.20.1250.20 3 391 1.8E-40 T 12-10-2018 AFR_20505 373915bf58379ab5881eb94acbc4f630 404 Pfam PF07690 Major Facilitator Superfamily 17 250 1.9E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_20505 373915bf58379ab5881eb94acbc4f630 404 SUPERFAMILY SSF103473 4 393 1.31E-51 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_11900 21eb914c68dfb3a5e824e4d956de11fc 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 100 4.0E-18 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_11900 21eb914c68dfb3a5e824e4d956de11fc 107 Gene3D G3DSA:3.30.750.24 4 104 1.7E-24 T 12-10-2018 IPR036513 STAS domain superfamily AFR_11900 21eb914c68dfb3a5e824e4d956de11fc 107 Pfam PF13466 STAS domain 17 95 1.6E-16 T 12-10-2018 IPR002645 STAS domain AFR_11900 21eb914c68dfb3a5e824e4d956de11fc 107 SUPERFAMILY SSF52091 7 100 2.75E-20 T 12-10-2018 IPR036513 STAS domain superfamily AFR_22760 34a49406ad8fdeb375cfb7fb3896b62f 303 SUPERFAMILY SSF56219 93 301 2.62E-26 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_22760 34a49406ad8fdeb375cfb7fb3896b62f 303 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 97 293 4.1E-12 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_22760 34a49406ad8fdeb375cfb7fb3896b62f 303 Gene3D G3DSA:3.60.10.10 92 302 5.9E-29 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_04130 0b3b28a8b8fc6f4217e5c2d5a241d43e 289 SUPERFAMILY SSF55486 137 277 8.86E-10 T 12-10-2018 AFR_04130 0b3b28a8b8fc6f4217e5c2d5a241d43e 289 Pfam PF11350 Protein of unknown function (DUF3152) 94 268 8.8E-33 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 AFR_03995 785241bb26c724c93cc9fa292a2542fc 151 Pfam PF00072 Response regulator receiver domain 14 134 3.2E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_03995 785241bb26c724c93cc9fa292a2542fc 151 Gene3D G3DSA:3.40.50.2300 2 150 1.2E-36 T 12-10-2018 AFR_03995 785241bb26c724c93cc9fa292a2542fc 151 SMART SM00448 12 134 5.0E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_03995 785241bb26c724c93cc9fa292a2542fc 151 SUPERFAMILY SSF52172 11 138 6.12E-33 T 12-10-2018 IPR011006 CheY-like superfamily AFR_35700 ae78c9d00f7f991f0c9ede25d1cfc737 217 Pfam PF01810 LysE type translocator 16 214 1.1E-46 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_35700 ae78c9d00f7f991f0c9ede25d1cfc737 217 PIRSF PIRSF006324 2 216 2.3E-51 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_18830 4364b854e813eab289fa988ae573237e 304 SUPERFAMILY SSF50370 182 303 1.07E-25 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_18830 4364b854e813eab289fa988ae573237e 304 Gene3D G3DSA:2.80.10.50 182 303 1.1E-26 T 12-10-2018 AFR_18830 4364b854e813eab289fa988ae573237e 304 Pfam PF00652 Ricin-type beta-trefoil lectin domain 189 301 5.7E-19 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_18830 4364b854e813eab289fa988ae573237e 304 SMART SM00458 188 304 5.9E-18 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_12010 c37450ebdc60da96ee982beb9256f537 124 Pfam PF03795 YCII-related domain 33 108 1.2E-12 T 12-10-2018 IPR005545 YCII-related AFR_12010 c37450ebdc60da96ee982beb9256f537 124 Gene3D G3DSA:3.30.70.1060 3 110 5.4E-26 T 12-10-2018 AFR_12010 c37450ebdc60da96ee982beb9256f537 124 SUPERFAMILY SSF54909 4 108 3.22E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_21545 d08447a2622af7baff4b8e442817ad5c 260 Pfam PF13672 Protein phosphatase 2C 15 135 3.0E-6 T 12-10-2018 AFR_21545 d08447a2622af7baff4b8e442817ad5c 260 SUPERFAMILY SSF81606 3 132 9.81E-7 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_32705 117cd97dd9713f7b5493392364ca3837 1023 Pfam PF03639 Glycosyl hydrolase family 81 85 719 4.4E-69 T 12-10-2018 IPR005200 Endo-1,3(4)-beta-glucanase GO:0052861 AFR_32705 117cd97dd9713f7b5493392364ca3837 1023 SUPERFAMILY SSF49785 810 945 5.03E-29 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32705 117cd97dd9713f7b5493392364ca3837 1023 Pfam PF00754 F5/8 type C domain 829 938 1.8E-23 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32705 117cd97dd9713f7b5493392364ca3837 1023 Gene3D G3DSA:2.60.120.260 820 950 4.9E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32705 117cd97dd9713f7b5493392364ca3837 1023 Gene3D G3DSA:2.10.10.20 979 1022 1.4E-21 T 12-10-2018 AFR_32705 117cd97dd9713f7b5493392364ca3837 1023 SUPERFAMILY SSF51055 979 1021 1.44E-14 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_32705 117cd97dd9713f7b5493392364ca3837 1023 SMART SM00495 977 1023 1.3E-12 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 AFR_23870 a74995c93d759d33d720bae1055d5e2e 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 157 9.6E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_23870 a74995c93d759d33d720bae1055d5e2e 168 SUPERFAMILY SSF88659 87 157 5.98E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_23870 a74995c93d759d33d720bae1055d5e2e 168 Gene3D G3DSA:1.10.10.10 89 159 2.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_23870 a74995c93d759d33d720bae1055d5e2e 168 Pfam PF04542 Sigma-70 region 2 7 72 1.3E-5 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23870 a74995c93d759d33d720bae1055d5e2e 168 Gene3D G3DSA:1.10.1740.10 1 74 4.6E-7 T 12-10-2018 AFR_23870 a74995c93d759d33d720bae1055d5e2e 168 SUPERFAMILY SSF88946 3 69 7.46E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_23870 a74995c93d759d33d720bae1055d5e2e 168 Pfam PF08281 Sigma-70, region 4 100 153 1.5E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_17810 33b9c116799c5ba198ac3258511e3b35 316 Pfam PF07859 alpha/beta hydrolase fold 88 289 7.2E-58 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_17810 33b9c116799c5ba198ac3258511e3b35 316 Gene3D G3DSA:3.40.50.1820 7 316 8.3E-89 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_17810 33b9c116799c5ba198ac3258511e3b35 316 SUPERFAMILY SSF53474 27 291 4.26E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_06490 f4794a8b6f1b7c7514df62385de36c4c 163 Pfam PF07291 Methylamine utilisation protein MauE 14 117 2.1E-9 T 12-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 AFR_03135 4e18529559b16ced20cd4bb7dbce5129 344 Pfam PF00248 Aldo/keto reductase family 5 315 3.4E-78 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_03135 4e18529559b16ced20cd4bb7dbce5129 344 Gene3D G3DSA:3.20.20.100 1 326 5.9E-111 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_03135 4e18529559b16ced20cd4bb7dbce5129 344 SUPERFAMILY SSF51430 2 317 2.75E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_07410 311a9b858dc64b56c439268f269cc812 419 SUPERFAMILY SSF50952 43 286 3.01E-8 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_07410 311a9b858dc64b56c439268f269cc812 419 Gene3D G3DSA:2.130.10.10 103 332 3.7E-5 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_07410 311a9b858dc64b56c439268f269cc812 419 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 163 194 1.3E-5 T 12-10-2018 IPR013431 Delta-60 repeat AFR_34185 37b0140f22b1334d889c1da6791a45d3 244 Pfam PF01061 ABC-2 type transporter 4 212 3.5E-28 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_34185 37b0140f22b1334d889c1da6791a45d3 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 100 125 1.7E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_34185 37b0140f22b1334d889c1da6791a45d3 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 134 158 1.7E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_34185 37b0140f22b1334d889c1da6791a45d3 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 171 190 1.7E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_34185 37b0140f22b1334d889c1da6791a45d3 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 191 210 1.7E-13 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_34185 37b0140f22b1334d889c1da6791a45d3 244 PIRSF PIRSF006648 1 244 4.0E-22 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_42965 1bbf888d7b00da9363927862d4797c83 355 Gene3D G3DSA:3.90.1530.30 99 162 1.9E-26 T 12-10-2018 AFR_42965 1bbf888d7b00da9363927862d4797c83 355 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 84 261 3.7E-62 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 AFR_42965 1bbf888d7b00da9363927862d4797c83 355 Gene3D G3DSA:1.10.10.2830 163 276 2.2E-36 T 12-10-2018 AFR_42965 1bbf888d7b00da9363927862d4797c83 355 SUPERFAMILY SSF110849 79 179 1.94E-29 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AFR_42965 1bbf888d7b00da9363927862d4797c83 355 SMART SM00470 86 176 3.1E-34 T 12-10-2018 IPR003115 ParB/Sulfiredoxin AFR_42965 1bbf888d7b00da9363927862d4797c83 355 SUPERFAMILY SSF109709 168 276 5.23E-34 T 12-10-2018 AFR_42965 1bbf888d7b00da9363927862d4797c83 355 Pfam PF02195 ParB-like nuclease domain 87 176 1.8E-25 T 12-10-2018 IPR003115 ParB/Sulfiredoxin AFR_11165 ef65dc19a21834e0e9fca1fc3d09f8d9 293 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 63 283 5.6E-11 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_11165 ef65dc19a21834e0e9fca1fc3d09f8d9 293 SUPERFAMILY SSF56219 58 290 4.97E-25 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_11165 ef65dc19a21834e0e9fca1fc3d09f8d9 293 Gene3D G3DSA:3.60.10.10 59 292 9.1E-32 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_22425 051c8d3c5d359e67ee1cd5a7871303ea 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.2E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22425 051c8d3c5d359e67ee1cd5a7871303ea 183 SUPERFAMILY SSF46689 1 81 7.77E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_22425 051c8d3c5d359e67ee1cd5a7871303ea 183 SUPERFAMILY SSF48498 81 179 3.78E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_22425 051c8d3c5d359e67ee1cd5a7871303ea 183 Gene3D G3DSA:1.10.357.10 1 183 5.7E-53 T 12-10-2018 AFR_22425 051c8d3c5d359e67ee1cd5a7871303ea 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_22425 051c8d3c5d359e67ee1cd5a7871303ea 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_36075 07c0670eb826e870f9b915171573e37b 208 Pfam PF06197 Protein of unknown function (DUF998) 1 174 3.8E-17 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_12495 1c50d7382612924f6628cc10b0efd259 249 SUPERFAMILY SSF49384 158 247 4.88E-11 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AFR_12495 1c50d7382612924f6628cc10b0efd259 249 Pfam PF00553 Cellulose binding domain 158 247 4.8E-6 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_12495 1c50d7382612924f6628cc10b0efd259 249 SMART SM00637 143 247 7.4E-4 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 AFR_12495 1c50d7382612924f6628cc10b0efd259 249 Gene3D G3DSA:2.60.40.290 141 249 8.6E-19 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 AFR_25815 8c617eea11f2429bfe6e15e254541613 214 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 175 2.9E-16 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_25815 8c617eea11f2429bfe6e15e254541613 214 Gene3D G3DSA:1.20.120.450 3 159 2.1E-24 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_25815 8c617eea11f2429bfe6e15e254541613 214 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 156 2.1E-17 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_25815 8c617eea11f2429bfe6e15e254541613 214 SUPERFAMILY SSF109854 3 162 7.33E-20 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_34930 fea69985b18e1e5c506c88e1d95138d7 261 Pfam PF01872 RibD C-terminal domain 45 246 1.6E-32 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_34930 fea69985b18e1e5c506c88e1d95138d7 261 SUPERFAMILY SSF53597 44 259 6.54E-39 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_34930 fea69985b18e1e5c506c88e1d95138d7 261 Gene3D G3DSA:3.40.430.10 15 260 7.6E-64 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_38510 978f86542e1daaf06c3e965780005405 99 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 95 2.1E-8 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 AFR_34865 c79624483ecd8cb66cfa7669e82fbf82 303 SUPERFAMILY SSF48150 108 283 2.97E-29 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFR_34865 c79624483ecd8cb66cfa7669e82fbf82 303 Gene3D G3DSA:1.10.340.30 120 231 3.2E-20 T 12-10-2018 AFR_01045 1f1aff27e9f518e4a85d7de061623236 86 SMART SM00530 12 68 8.2E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_01045 1f1aff27e9f518e4a85d7de061623236 86 Gene3D G3DSA:1.10.260.40 7 82 1.8E-11 T 12-10-2018 AFR_01045 1f1aff27e9f518e4a85d7de061623236 86 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 12 73 7.9E-19 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_01045 1f1aff27e9f518e4a85d7de061623236 86 SUPERFAMILY SSF47413 11 74 2.62E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_13700 490d66dbb4715d60f6396a03cb81ddea 427 TIGRFAM TIGR00797 matE: MATE efflux family protein 30 400 6.1E-48 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_13700 490d66dbb4715d60f6396a03cb81ddea 427 PIRSF PIRSF006603 11 424 2.8E-73 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_13700 490d66dbb4715d60f6396a03cb81ddea 427 Pfam PF01554 MatE 231 387 8.3E-20 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_13700 490d66dbb4715d60f6396a03cb81ddea 427 Pfam PF01554 MatE 19 166 2.7E-15 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFR_12740 7cc2063af910d0faac999f65e867f530 264 Pfam PF13649 Methyltransferase domain 47 137 2.9E-20 T 12-10-2018 AFR_12740 7cc2063af910d0faac999f65e867f530 264 SUPERFAMILY SSF53335 11 165 8.14E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_12740 7cc2063af910d0faac999f65e867f530 264 Gene3D G3DSA:3.40.50.150 12 255 2.7E-39 T 12-10-2018 AFR_23330 be7392c6b0a7686ebf70656a9f075170 329 SUPERFAMILY SSF53756 69 300 8.16E-16 T 12-10-2018 AFR_23330 be7392c6b0a7686ebf70656a9f075170 329 Gene3D G3DSA:3.40.50.2000 143 306 3.1E-13 T 12-10-2018 AFR_23330 be7392c6b0a7686ebf70656a9f075170 329 Gene3D G3DSA:3.40.50.2000 50 142 3.1E-13 T 12-10-2018 AFR_10955 79a16e1b40654d6ff6eec83be02f5a57 180 Gene3D G3DSA:3.40.50.150 1 162 3.0E-40 T 12-10-2018 AFR_10955 79a16e1b40654d6ff6eec83be02f5a57 180 SUPERFAMILY SSF53335 6 163 2.63E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_10955 79a16e1b40654d6ff6eec83be02f5a57 180 Pfam PF13649 Methyltransferase domain 39 131 1.4E-23 T 12-10-2018 AFR_39960 851eec47a472fb7f857761aeafecf815 205 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 192 7.0E-47 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFR_39960 851eec47a472fb7f857761aeafecf815 205 Pfam PF01914 MarC family integral membrane protein 4 195 3.7E-49 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFR_42195 764b055e77986e860b5cd20faefdfc5c 266 Pfam PF06276 Ferric iron reductase FhuF-like transporter 83 206 3.0E-7 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain AFR_08955 af272b8380766d9e6c73acb44787cab0 70 Gene3D G3DSA:3.40.50.2300 1 70 2.1E-11 T 12-10-2018 AFR_08955 af272b8380766d9e6c73acb44787cab0 70 Pfam PF00072 Response regulator receiver domain 1 64 2.4E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_08955 af272b8380766d9e6c73acb44787cab0 70 SUPERFAMILY SSF52172 1 69 2.56E-13 T 12-10-2018 IPR011006 CheY-like superfamily AFR_06565 afb610174d7f106c6903e3b7517cef1f 257 Pfam PF00293 NUDIX domain 100 210 1.1E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_06565 afb610174d7f106c6903e3b7517cef1f 257 Gene3D G3DSA:3.90.79.10 89 240 2.6E-29 T 12-10-2018 AFR_06565 afb610174d7f106c6903e3b7517cef1f 257 SUPERFAMILY SSF55811 8 216 4.46E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_06565 afb610174d7f106c6903e3b7517cef1f 257 PRINTS PR00502 NUDIX hydrolase family signature 123 137 1.8E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_06565 afb610174d7f106c6903e3b7517cef1f 257 PRINTS PR00502 NUDIX hydrolase family signature 137 152 1.8E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_35015 b78dab6af2dfb79165f82db75c29a6a8 376 Pfam PF12706 Beta-lactamase superfamily domain 127 323 8.6E-54 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_35015 b78dab6af2dfb79165f82db75c29a6a8 376 SUPERFAMILY SSF56281 110 362 4.82E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_35015 b78dab6af2dfb79165f82db75c29a6a8 376 Gene3D G3DSA:3.60.15.10 97 366 2.4E-84 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_35015 b78dab6af2dfb79165f82db75c29a6a8 376 PIRSF PIRSF038896 23 365 1.9E-91 T 12-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 AFR_32685 ab8c17a6d0287f7c4ff5b1b083e7fe5f 194 Pfam PF09335 SNARE associated Golgi protein 33 148 4.7E-14 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 Gene3D G3DSA:1.10.155.10 1 71 8.9E-12 T 12-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 Pfam PF01739 CheR methyltransferase, SAM binding domain 73 259 9.3E-55 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 PRINTS PR00996 Glutamate methyltransferase family signature 27 40 1.3E-35 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 1.3E-35 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 PRINTS PR00996 Glutamate methyltransferase family signature 66 78 1.3E-35 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 1.3E-35 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 PRINTS PR00996 Glutamate methyltransferase family signature 139 155 1.3E-35 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 1.3E-35 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 SMART SM00138 5 267 1.8E-87 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 Gene3D G3DSA:3.40.50.150 72 269 6.1E-55 T 12-10-2018 AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 SUPERFAMILY SSF53335 73 258 5.08E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 Pfam PF03705 CheR methyltransferase, all-alpha domain 6 58 2.1E-8 T 12-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AFR_40575 6f3a6fe7a3fdfd47efd6cd4bcb453bfe 281 SUPERFAMILY SSF47757 2 72 1.44E-12 T 12-10-2018 AFR_16610 73867c9d91b73f3f3bd71c570f6d09b7 341 SUPERFAMILY SSF53448 4 204 3.56E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16610 73867c9d91b73f3f3bd71c570f6d09b7 341 Gene3D G3DSA:3.90.550.10 2 202 1.8E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16610 73867c9d91b73f3f3bd71c570f6d09b7 341 Pfam PF00535 Glycosyl transferase family 2 7 117 3.4E-12 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_14440 663cea2d5fff8622d49930a2e66fd336 148 SUPERFAMILY SSF53474 40 139 9.66E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_14440 663cea2d5fff8622d49930a2e66fd336 148 Gene3D G3DSA:3.40.50.1820 12 144 2.3E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_17405 825b874ee5ad891b6e59bc1db346df85 448 Gene3D G3DSA:3.40.50.200 167 432 1.3E-43 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_17405 825b874ee5ad891b6e59bc1db346df85 448 SUPERFAMILY SSF52743 166 435 1.44E-44 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_17405 825b874ee5ad891b6e59bc1db346df85 448 PRINTS PR00723 Subtilisin serine protease family (S8) signature 223 236 4.1E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_17405 825b874ee5ad891b6e59bc1db346df85 448 PRINTS PR00723 Subtilisin serine protease family (S8) signature 394 410 4.1E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_17405 825b874ee5ad891b6e59bc1db346df85 448 PRINTS PR00723 Subtilisin serine protease family (S8) signature 179 198 4.1E-9 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related AFR_17405 825b874ee5ad891b6e59bc1db346df85 448 Pfam PF00082 Subtilase family 227 410 4.0E-14 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_23360 da638e40602ebecc55ac6b061c91c6f0 710 Pfam PF02810 SEC-C motif 684 702 1.8E-6 T 12-10-2018 IPR004027 SEC-C motif AFR_33290 4dc77153b199e42ea9092912d5c88754 269 Pfam PF13531 Bacterial extracellular solute-binding protein 49 267 1.3E-44 T 12-10-2018 AFR_33290 4dc77153b199e42ea9092912d5c88754 269 Gene3D G3DSA:3.40.190.10 127 229 3.2E-58 T 12-10-2018 AFR_33290 4dc77153b199e42ea9092912d5c88754 269 Gene3D G3DSA:3.40.190.10 50 266 3.2E-58 T 12-10-2018 AFR_33290 4dc77153b199e42ea9092912d5c88754 269 PIRSF PIRSF004846 1 269 1.3E-62 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 AFR_33290 4dc77153b199e42ea9092912d5c88754 269 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 54 263 2.3E-38 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 AFR_33290 4dc77153b199e42ea9092912d5c88754 269 SUPERFAMILY SSF53850 48 268 2.37E-52 T 12-10-2018 AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 SUPERFAMILY SSF46955 1 112 3.26E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 Pfam PF13411 MerR HTH family regulatory protein 1 67 2.3E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 SMART SM00422 1 69 4.6E-22 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.5E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.5E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.5E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 Gene3D G3DSA:1.10.1660.10 1 119 9.4E-28 T 12-10-2018 AFR_13760 18a5e2c0c955f9026b7a5ea0ca8d3cd5 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_40470 f59622b304b24880fa9320d444ee9cca 198 Pfam PF03963 Flagellar hook capping protein - N-terminal region 16 87 1.6E-18 T 12-10-2018 IPR005648 Flagellar hook capping protein AFR_18610 8dfa775c53249dcd381fd75c9fed9a90 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 92 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFR_18610 8dfa775c53249dcd381fd75c9fed9a90 397 Pfam PF07690 Major Facilitator Superfamily 32 360 3.4E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_18610 8dfa775c53249dcd381fd75c9fed9a90 397 Gene3D G3DSA:1.20.1250.20 23 394 3.3E-34 T 12-10-2018 AFR_18610 8dfa775c53249dcd381fd75c9fed9a90 397 SUPERFAMILY SSF103473 26 394 2.09E-37 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_10155 a01b48ba8060cc7f3082490ade35ad3d 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 258 47.477 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFR_10155 a01b48ba8060cc7f3082490ade35ad3d 258 Gene3D G3DSA:3.20.20.70 1 258 3.8E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_10155 a01b48ba8060cc7f3082490ade35ad3d 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 258 2.3E-108 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFR_10155 a01b48ba8060cc7f3082490ade35ad3d 258 SUPERFAMILY SSF51366 4 258 7.46E-80 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFR_10155 a01b48ba8060cc7f3082490ade35ad3d 258 Pfam PF00977 Histidine biosynthesis protein 6 242 1.5E-84 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 Gene3D G3DSA:1.20.120.220 90 263 5.5E-34 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 Pfam PF00119 ATP synthase A chain 40 255 1.3E-50 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 SUPERFAMILY SSF81336 90 255 6.28E-37 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 Hamap MF_01393 ATP synthase subunit a [atpB]. 16 262 13.721 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 ProSitePatterns PS00449 ATP synthase a subunit signature. 185 194 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 PRINTS PR00123 ATP synthase A subunit signature 242 257 1.1E-18 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 PRINTS PR00123 ATP synthase A subunit signature 97 113 1.1E-18 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 PRINTS PR00123 ATP synthase A subunit signature 182 204 1.1E-18 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_37365 48b857b935a75bc98f5f3b3f1d9205fd 263 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 33 257 1.1E-43 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFR_41000 9f8bc379b2277f409ed894cbcb8b19ea 379 Gene3D G3DSA:3.40.50.2000 16 181 3.5E-19 T 12-10-2018 AFR_41000 9f8bc379b2277f409ed894cbcb8b19ea 379 Pfam PF00534 Glycosyl transferases group 1 185 340 1.9E-27 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_41000 9f8bc379b2277f409ed894cbcb8b19ea 379 SUPERFAMILY SSF53756 10 362 7.07E-64 T 12-10-2018 AFR_41000 9f8bc379b2277f409ed894cbcb8b19ea 379 Pfam PF13439 Glycosyltransferase Family 4 16 176 8.2E-20 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_41000 9f8bc379b2277f409ed894cbcb8b19ea 379 Gene3D G3DSA:3.40.50.2000 182 345 1.0E-35 T 12-10-2018 AFR_40840 b7d12ed9ba73899bd2b1a1918ad5521d 833 Pfam PF07054 Pericardin like repeat 601 632 9.5E-6 T 12-10-2018 IPR009765 Pericardin-like repeat AFR_40840 b7d12ed9ba73899bd2b1a1918ad5521d 833 Pfam PF07054 Pericardin like repeat 631 663 1.6E-6 T 12-10-2018 IPR009765 Pericardin-like repeat AFR_40840 b7d12ed9ba73899bd2b1a1918ad5521d 833 Pfam PF07054 Pericardin like repeat 548 580 4.0E-7 T 12-10-2018 IPR009765 Pericardin-like repeat AFR_40840 b7d12ed9ba73899bd2b1a1918ad5521d 833 Pfam PF13367 Protease prsW family 68 269 2.5E-46 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 AFR_02635 17fb1638b96de06d333ed0fecc5bc8e3 158 Pfam PF00072 Response regulator receiver domain 4 115 4.9E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_02635 17fb1638b96de06d333ed0fecc5bc8e3 158 SUPERFAMILY SSF52172 3 127 2.85E-39 T 12-10-2018 IPR011006 CheY-like superfamily AFR_02635 17fb1638b96de06d333ed0fecc5bc8e3 158 SMART SM00448 2 115 1.6E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_02635 17fb1638b96de06d333ed0fecc5bc8e3 158 Gene3D G3DSA:3.40.50.12740 2 156 3.2E-43 T 12-10-2018 AFR_21630 5b6d249d455274476ec2b87d7a7dd150 305 Pfam PF03466 LysR substrate binding domain 88 289 3.2E-36 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_21630 5b6d249d455274476ec2b87d7a7dd150 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_21630 5b6d249d455274476ec2b87d7a7dd150 305 Gene3D G3DSA:3.40.190.290 92 292 6.9E-38 T 12-10-2018 AFR_21630 5b6d249d455274476ec2b87d7a7dd150 305 SUPERFAMILY SSF46785 1 111 5.08E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_21630 5b6d249d455274476ec2b87d7a7dd150 305 SUPERFAMILY SSF53850 88 290 4.34E-35 T 12-10-2018 AFR_21630 5b6d249d455274476ec2b87d7a7dd150 305 Gene3D G3DSA:1.10.10.10 1 89 5.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_03005 017c66b870556ee26d76dbc2788d7d2c 267 Gene3D G3DSA:2.60.120.200 30 265 2.4E-17 T 12-10-2018 AFR_03005 017c66b870556ee26d76dbc2788d7d2c 267 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 123 264 3.6E-12 T 12-10-2018 AFR_03005 017c66b870556ee26d76dbc2788d7d2c 267 SUPERFAMILY SSF49899 57 264 7.25E-16 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_42960 98dd7c7212c67ea8ea34c9e466feb974 366 Gene3D G3DSA:3.30.428.10 16 133 1.7E-9 T 12-10-2018 IPR036265 HIT-like superfamily AFR_42960 98dd7c7212c67ea8ea34c9e466feb974 366 SUPERFAMILY SSF54197 23 155 1.19E-13 T 12-10-2018 IPR036265 HIT-like superfamily AFR_25785 10a43b11a2cd35cec5d7b8f1e42a6717 471 SMART SM00530 6 61 1.0E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_25785 10a43b11a2cd35cec5d7b8f1e42a6717 471 Gene3D G3DSA:1.10.260.40 1 77 4.8E-18 T 12-10-2018 AFR_25785 10a43b11a2cd35cec5d7b8f1e42a6717 471 Pfam PF06114 IrrE N-terminal-like domain 225 296 4.4E-8 T 12-10-2018 IPR010359 IrrE N-terminal-like domain AFR_25785 10a43b11a2cd35cec5d7b8f1e42a6717 471 Pfam PF13560 Helix-turn-helix domain 3 60 1.7E-12 T 12-10-2018 AFR_25785 10a43b11a2cd35cec5d7b8f1e42a6717 471 SUPERFAMILY SSF47413 2 65 6.19E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_10210 54635ad72435181fe959fbb57d5c18ed 243 Gene3D G3DSA:2.20.25.570 143 202 1.3E-78 T 12-10-2018 AFR_10210 54635ad72435181fe959fbb57d5c18ed 243 Gene3D G3DSA:3.40.50.150 10 241 1.3E-78 T 12-10-2018 AFR_10210 54635ad72435181fe959fbb57d5c18ed 243 Pfam PF13649 Methyltransferase domain 42 135 7.3E-12 T 12-10-2018 AFR_10210 54635ad72435181fe959fbb57d5c18ed 243 SUPERFAMILY SSF53335 13 230 1.58E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_31395 99ba8025668a2bfb537a6488b70c39f7 260 SUPERFAMILY SSF54593 128 239 4.83E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_31395 99ba8025668a2bfb537a6488b70c39f7 260 Gene3D G3DSA:3.10.180.10 7 115 7.3E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_31395 99ba8025668a2bfb537a6488b70c39f7 260 Gene3D G3DSA:3.10.180.10 123 239 4.0E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_31395 99ba8025668a2bfb537a6488b70c39f7 260 SUPERFAMILY SSF54593 11 158 7.92E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_10580 3f88ca8fe8d9bf72b04470f60ca41096 84 PRINTS PR01651 Protein-export SecG membrane protein signature 42 58 2.5E-9 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFR_10580 3f88ca8fe8d9bf72b04470f60ca41096 84 PRINTS PR01651 Protein-export SecG membrane protein signature 58 80 2.5E-9 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFR_10580 3f88ca8fe8d9bf72b04470f60ca41096 84 PRINTS PR01651 Protein-export SecG membrane protein signature 7 27 2.5E-9 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFR_10580 3f88ca8fe8d9bf72b04470f60ca41096 84 PRINTS PR01651 Protein-export SecG membrane protein signature 27 41 2.5E-9 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFR_10580 3f88ca8fe8d9bf72b04470f60ca41096 84 Pfam PF03840 Preprotein translocase SecG subunit 9 76 2.6E-20 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFR_10580 3f88ca8fe8d9bf72b04470f60ca41096 84 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 8 76 3.0E-21 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFR_12600 1940e9569a701dc046a8505ea402233f 172 Gene3D G3DSA:3.30.530.20 25 166 1.2E-10 T 12-10-2018 IPR023393 START-like domain superfamily AFR_12600 1940e9569a701dc046a8505ea402233f 172 SUPERFAMILY SSF55961 48 165 1.94E-9 T 12-10-2018 AFR_12600 1940e9569a701dc046a8505ea402233f 172 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 40 161 1.1E-9 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_30930 6e523e6ddf3eb2e8ab9e02f102d77435 266 Pfam PF01774 UreD urease accessory protein 43 199 7.3E-27 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 AFR_30930 6e523e6ddf3eb2e8ab9e02f102d77435 266 Hamap MF_01384 Urease accessory protein UreD [ureD]. 1 244 17.373 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 AFR_19920 a2aaf0cb909c4899ce6a315b788eb230 410 SUPERFAMILY SSF55874 304 407 5.89E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19920 a2aaf0cb909c4899ce6a315b788eb230 410 SMART SM00387 320 410 2.1E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_19920 a2aaf0cb909c4899ce6a315b788eb230 410 Pfam PF07730 Histidine kinase 220 286 6.4E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_19920 a2aaf0cb909c4899ce6a315b788eb230 410 Gene3D G3DSA:3.30.565.10 295 408 2.5E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_19920 a2aaf0cb909c4899ce6a315b788eb230 410 Pfam PF13796 Putative sensor 20 191 1.3E-23 T 12-10-2018 IPR025828 Putative sensor domain AFR_19360 683fdb57837bc98e0dd1ebee7520b409 169 SUPERFAMILY SSF55144 15 167 3.66E-15 T 12-10-2018 IPR009097 Cyclic phosphodiesterase AFR_19360 683fdb57837bc98e0dd1ebee7520b409 169 Gene3D G3DSA:3.90.1140.10 6 168 1.5E-22 T 12-10-2018 AFR_19360 683fdb57837bc98e0dd1ebee7520b409 169 Pfam PF13563 2'-5' RNA ligase superfamily 15 157 1.8E-22 T 12-10-2018 AFR_19220 f429fee3687634082322e753ff8ca16e 125 SUPERFAMILY SSF55620 38 109 2.06E-6 T 12-10-2018 AFR_11345 386ca8992ff49d8ca8aa7d3fbe269abc 114 Gene3D G3DSA:3.10.450.50 2 109 1.8E-26 T 12-10-2018 AFR_11345 386ca8992ff49d8ca8aa7d3fbe269abc 114 Pfam PF12680 SnoaL-like domain 10 88 1.7E-10 T 12-10-2018 IPR037401 SnoaL-like domain AFR_11345 386ca8992ff49d8ca8aa7d3fbe269abc 114 SUPERFAMILY SSF54427 4 102 6.69E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 7 383 46.45 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 PIRSF PIRSF001413 1 384 3.7E-137 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 56 370 9.7E-53 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 SUPERFAMILY SSF53686 8 381 1.7E-129 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 Gene3D G3DSA:3.40.50.1100 15 210 3.9E-158 T 12-10-2018 AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 Gene3D G3DSA:3.40.50.1100 59 376 3.9E-158 T 12-10-2018 AFR_20260 800a32218048c7bf66d4e33044b1e35e 384 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 12 381 1.3E-156 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFR_27400 92e9ab7eb8fed2106022b6556fae3be8 351 Pfam PF00144 Beta-lactamase 2 335 6.0E-63 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_27400 92e9ab7eb8fed2106022b6556fae3be8 351 SUPERFAMILY SSF56601 2 341 9.98E-68 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_27400 92e9ab7eb8fed2106022b6556fae3be8 351 Gene3D G3DSA:3.40.710.30 1 349 4.3E-113 T 12-10-2018 AFR_21025 0c2a6659808aa42b41470f1af6cbd5ad 407 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 13 407 2.6E-174 T 12-10-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 KEGG: 00500+2.4.1.342|MetaCyc: PWY-7900 AFR_21025 0c2a6659808aa42b41470f1af6cbd5ad 407 Gene3D G3DSA:3.40.50.2000 187 386 2.4E-79 T 12-10-2018 AFR_21025 0c2a6659808aa42b41470f1af6cbd5ad 407 Gene3D G3DSA:3.40.50.2000 18 403 2.4E-79 T 12-10-2018 AFR_21025 0c2a6659808aa42b41470f1af6cbd5ad 407 Pfam PF00534 Glycosyl transferases group 1 202 383 6.2E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_21025 0c2a6659808aa42b41470f1af6cbd5ad 407 SUPERFAMILY SSF53756 21 407 7.85E-82 T 12-10-2018 AFR_21025 0c2a6659808aa42b41470f1af6cbd5ad 407 Pfam PF13439 Glycosyltransferase Family 4 27 191 5.1E-30 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_12310 ff5ea7da5b29e7fd9e6de2322645f3e6 292 Pfam PF02517 CAAX protease self-immunity 136 230 2.7E-11 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFR_02235 d5ce07e57ec9b30fd7ad96693e47daac 245 Pfam PF14014 Protein of unknown function (DUF4230) 83 240 1.1E-35 T 12-10-2018 IPR025324 Protein of unknown function DUF4230 AFR_29515 1b3f7500d30e78998c074b1477c6a041 126 SUPERFAMILY SSF56349 26 88 1.59E-9 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_29515 1b3f7500d30e78998c074b1477c6a041 126 Pfam PF00589 Phage integrase family 28 79 6.8E-7 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFR_29515 1b3f7500d30e78998c074b1477c6a041 126 Gene3D G3DSA:1.10.443.10 8 94 4.7E-10 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFR_38295 3395d33a394b1c6f6de1431dfaa15b95 368 Gene3D G3DSA:2.60.40.10 147 274 1.0E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_06080 6285de1c908976c5d79a46cce8a554e2 94 Pfam PF04248 Domain of unknown function (DUF427) 3 88 1.4E-33 T 12-10-2018 IPR007361 Domain of unknown function DUF427 AFR_06080 6285de1c908976c5d79a46cce8a554e2 94 Gene3D G3DSA:2.170.150.40 3 94 3.4E-30 T 12-10-2018 AFR_42380 9bb3df78a7b4d093702d4fbbcb6dbcca 481 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 468 8.4E-83 T 12-10-2018 IPR007795 Type VII secretion system EccB AFR_42380 9bb3df78a7b4d093702d4fbbcb6dbcca 481 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 476 3.7E-81 T 12-10-2018 IPR007795 Type VII secretion system EccB AFR_42380 9bb3df78a7b4d093702d4fbbcb6dbcca 481 Gene3D G3DSA:2.40.50.900 70 151 8.6E-21 T 12-10-2018 AFR_42380 9bb3df78a7b4d093702d4fbbcb6dbcca 481 Gene3D G3DSA:2.40.50.910 253 310 3.6E-5 T 12-10-2018 AFR_15370 78bc74c69e2a43f9118ad393b4214ea3 534 Gene3D G3DSA:1.20.1250.20 21 404 1.9E-37 T 12-10-2018 AFR_15370 78bc74c69e2a43f9118ad393b4214ea3 534 Pfam PF05977 Transmembrane secretion effector 15 530 1.1E-162 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_15370 78bc74c69e2a43f9118ad393b4214ea3 534 SUPERFAMILY SSF103473 25 407 4.58E-46 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 Gene3D G3DSA:3.40.50.880 1 197 2.0E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 Gene3D G3DSA:1.10.10.60 200 303 1.9E-29 T 12-10-2018 AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 SMART SM00342 215 298 2.8E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 SUPERFAMILY SSF46689 201 248 5.82E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 SUPERFAMILY SSF52317 1 181 1.11E-44 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 Pfam PF01965 DJ-1/PfpI family 10 159 1.1E-17 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 Pfam PF12833 Helix-turn-helix domain 221 299 1.0E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_17450 25fa2835a1139486e3f0e33ed2f0f7be 304 SUPERFAMILY SSF46689 251 302 1.06E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_06180 1dde66e51ee89ce7efa6a9e834415207 509 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 42 481 1.9E-93 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 AFR_06180 1dde66e51ee89ce7efa6a9e834415207 509 Gene3D G3DSA:1.10.4160.10 26 497 1.5E-109 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily AFR_35410 8c51a30fcb679ddb66647a6ad9f5bce8 261 Pfam PF07070 SpoOM protein 3 218 9.2E-83 T 12-10-2018 IPR009776 Sporulation stage 0, protein M AFR_15005 8cac14836f6b44425cb20b4d9edf26d6 265 SUPERFAMILY SSF56281 1 246 2.1E-22 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_15005 8cac14836f6b44425cb20b4d9edf26d6 265 SMART SM00849 31 245 8.5E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_15005 8cac14836f6b44425cb20b4d9edf26d6 265 Pfam PF00753 Metallo-beta-lactamase superfamily 31 208 8.9E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFR_15005 8cac14836f6b44425cb20b4d9edf26d6 265 Gene3D G3DSA:3.60.15.10 1 255 3.4E-31 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFR_31760 010eeb19b47be47814d1d74578b3fa9f 556 Pfam PF00474 Sodium:solute symporter family 45 454 7.5E-51 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFR_31760 010eeb19b47be47814d1d74578b3fa9f 556 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 45 454 2.5E-76 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFR_31760 010eeb19b47be47814d1d74578b3fa9f 556 Gene3D G3DSA:1.20.1730.10 34 555 5.7E-112 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily AFR_38395 31660628e9f288727bc9e15f59e41a58 438 SUPERFAMILY SSF63411 7 230 5.83E-34 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_38395 31660628e9f288727bc9e15f59e41a58 438 SUPERFAMILY SSF63411 239 431 4.33E-36 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_38395 31660628e9f288727bc9e15f59e41a58 438 Pfam PF00675 Insulinase (Peptidase family M16) 58 164 3.9E-9 T 12-10-2018 IPR011765 Peptidase M16, N-terminal AFR_38395 31660628e9f288727bc9e15f59e41a58 438 Gene3D G3DSA:3.30.830.10 232 425 8.2E-44 T 12-10-2018 AFR_38395 31660628e9f288727bc9e15f59e41a58 438 Gene3D G3DSA:3.30.830.10 22 222 1.6E-31 T 12-10-2018 AFR_38395 31660628e9f288727bc9e15f59e41a58 438 Pfam PF05193 Peptidase M16 inactive domain 181 352 7.3E-19 T 12-10-2018 IPR007863 Peptidase M16, C-terminal AFR_42465 84a08b5cd27d356ab9f76748f616f2c9 212 ProDom PD068376 ORF2 SECRETED GLNII PRECURSOR SIGNAL 41 212 6.0E-41 T 12-10-2018 AFR_42465 84a08b5cd27d356ab9f76748f616f2c9 212 Gene3D G3DSA:2.40.40.10 132 208 2.0E-5 T 12-10-2018 IPR036908 RlpA-like domain superfamily AFR_24585 27178c956757b97c81db0ab85a7c1fde 136 Gene3D G3DSA:1.25.40.380 1 136 7.1E-57 T 12-10-2018 IPR036287 Rv1873-like superfamily AFR_24585 27178c956757b97c81db0ab85a7c1fde 136 PIRSF PIRSF008546 2 136 6.3E-58 T 12-10-2018 IPR014937 Protein of unknown function DUF1810 AFR_24585 27178c956757b97c81db0ab85a7c1fde 136 Pfam PF08837 Protein of unknown function (DUF1810) 3 136 1.1E-59 T 12-10-2018 IPR014937 Protein of unknown function DUF1810 AFR_24585 27178c956757b97c81db0ab85a7c1fde 136 SUPERFAMILY SSF140736 3 136 1.57E-59 T 12-10-2018 IPR036287 Rv1873-like superfamily AFR_32555 01419146ea8e7c63e5981078afd61910 288 SUPERFAMILY SSF53300 64 207 1.14E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_32555 01419146ea8e7c63e5981078afd61910 288 Gene3D G3DSA:3.40.50.410 57 282 4.3E-8 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_32555 01419146ea8e7c63e5981078afd61910 288 Pfam PF01882 Protein of unknown function DUF58 25 112 1.0E-20 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_07240 6a80718229722cf8e2ad0419aa907686 111 Pfam PF03795 YCII-related domain 16 100 5.4E-15 T 12-10-2018 IPR005545 YCII-related AFR_07240 6a80718229722cf8e2ad0419aa907686 111 Gene3D G3DSA:3.30.70.1060 2 103 3.2E-24 T 12-10-2018 AFR_07240 6a80718229722cf8e2ad0419aa907686 111 SUPERFAMILY SSF54909 5 100 5.09E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_18385 c49d5f16457d443d446cf77bfbb0c682 523 Gene3D G3DSA:3.40.800.10 105 399 5.5E-55 T 12-10-2018 AFR_18385 c49d5f16457d443d446cf77bfbb0c682 523 Pfam PF00491 Arginase family 114 367 2.1E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 AFR_18385 c49d5f16457d443d446cf77bfbb0c682 523 SUPERFAMILY SSF52768 110 388 1.44E-47 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily AFR_22200 bd235545cc8d0a5bb943d250e2626845 314 Gene3D G3DSA:3.40.109.10 102 314 2.4E-54 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_22200 bd235545cc8d0a5bb943d250e2626845 314 Gene3D G3DSA:3.40.109.10 4 97 3.6E-26 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_22200 bd235545cc8d0a5bb943d250e2626845 314 SUPERFAMILY SSF55469 103 313 5.45E-11 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_22200 bd235545cc8d0a5bb943d250e2626845 314 SUPERFAMILY SSF55469 7 76 4.45E-7 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_22200 bd235545cc8d0a5bb943d250e2626845 314 Pfam PF00881 Nitroreductase family 114 280 1.2E-7 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFR_21260 cc59d85085b9726e3a4fa4ca371d33f0 186 SUPERFAMILY SSF54593 64 184 9.05E-7 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21260 cc59d85085b9726e3a4fa4ca371d33f0 186 Gene3D G3DSA:3.10.180.10 51 186 4.1E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_13250 30d4df564b01881f182a9910a31de1b4 161 Gene3D G3DSA:3.40.50.720 1 156 3.1E-31 T 12-10-2018 AFR_13250 30d4df564b01881f182a9910a31de1b4 161 SUPERFAMILY SSF51735 3 138 1.87E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13250 30d4df564b01881f182a9910a31de1b4 161 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 91 1.2E-16 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_04070 f9f05235f56ebedc091be308541efd35 323 Pfam PF00877 NlpC/P60 family 223 315 6.8E-24 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_04070 f9f05235f56ebedc091be308541efd35 323 Gene3D G3DSA:3.90.1720.10 124 316 4.5E-44 T 12-10-2018 AFR_04070 f9f05235f56ebedc091be308541efd35 323 SUPERFAMILY SSF54001 206 322 7.36E-37 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_37235 7126657df2c23ade4d3bbd214b06e5fc 266 Gene3D G3DSA:3.40.50.1820 13 224 3.2E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_37235 7126657df2c23ade4d3bbd214b06e5fc 266 SUPERFAMILY SSF53474 11 221 2.98E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_26085 eb51a826e7a0a79af8ef92ff6dfd8571 224 Pfam PF06736 Protein of unknown function (DUF1211) 16 117 5.0E-27 T 12-10-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 AFR_18250 d7717f17a4eed9121a50535eb64c8ad5 416 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 14 114 8.3E-15 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AFR_18250 d7717f17a4eed9121a50535eb64c8ad5 416 Gene3D G3DSA:3.40.50.720 13 166 1.5E-36 T 12-10-2018 AFR_18250 d7717f17a4eed9121a50535eb64c8ad5 416 SUPERFAMILY SSF51735 13 159 4.55E-17 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_21125 c8a40d5cb9b0c60aa261f16764103294 299 SUPERFAMILY SSF103481 190 274 2.09E-6 T 12-10-2018 AFR_21125 c8a40d5cb9b0c60aa261f16764103294 299 Pfam PF00892 EamA-like transporter family 141 267 1.5E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_13770 644c4795d0075a51fb5f98d8b49dab01 256 Gene3D G3DSA:2.40.30.170 157 206 5.8E-12 T 12-10-2018 AFR_13770 644c4795d0075a51fb5f98d8b49dab01 256 Pfam PF13437 HlyD family secretion protein 126 206 4.8E-11 T 12-10-2018 AFR_13770 644c4795d0075a51fb5f98d8b49dab01 256 Gene3D G3DSA:2.40.50.100 115 156 5.8E-12 T 12-10-2018 AFR_13770 644c4795d0075a51fb5f98d8b49dab01 256 Gene3D G3DSA:1.10.287.470 95 114 5.8E-12 T 12-10-2018 AFR_13770 644c4795d0075a51fb5f98d8b49dab01 256 SUPERFAMILY SSF51230 89 154 4.84E-5 T 12-10-2018 IPR011053 Single hybrid motif AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 Gene3D G3DSA:3.40.190.80 163 267 2.8E-11 T 12-10-2018 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 Pfam PF00459 Inositol monophosphatase family 11 259 1.8E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 SUPERFAMILY SSF56655 6 266 4.58E-50 T 12-10-2018 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 3.0E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 3.0E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 138 161 3.0E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 3.0E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 3.0E-19 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFR_04000 0a9189a6e8556232badf95a0d09dac2f 268 Gene3D G3DSA:3.30.540.10 1 151 4.8E-33 T 12-10-2018 AFR_21640 d88c412c9128349efdedb31fb81d44c3 369 SUPERFAMILY SSF56601 8 361 1.13E-61 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_21640 d88c412c9128349efdedb31fb81d44c3 369 Gene3D G3DSA:3.40.710.30 4 369 2.1E-111 T 12-10-2018 AFR_21640 d88c412c9128349efdedb31fb81d44c3 369 Pfam PF00144 Beta-lactamase 18 358 2.4E-53 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_12195 0b07d7273918aa297dd076965b48d34f 121 Pfam PF13586 Transposase DDE domain 1 81 2.6E-12 T 12-10-2018 IPR025668 Transposase DDE domain AFR_33035 f30c399328040cbfb7c1c4bdae7f19fd 368 SUPERFAMILY SSF51004 59 349 3.01E-43 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily AFR_33035 f30c399328040cbfb7c1c4bdae7f19fd 368 Gene3D G3DSA:2.130.10.10 28 368 3.7E-91 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_33035 f30c399328040cbfb7c1c4bdae7f19fd 368 Pfam PF10282 Lactonase, 7-bladed beta-propeller 43 366 1.3E-87 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller AFR_40150 c345421fc4bc61dd37c343623b3cabe2 73 Pfam PF09723 Zinc ribbon domain 1 40 2.0E-12 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFR_40150 c345421fc4bc61dd37c343623b3cabe2 73 SMART SM00834 1 42 5.2E-15 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFR_40150 c345421fc4bc61dd37c343623b3cabe2 73 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 1.6E-16 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFR_22185 f13f57fe7d91a23c00809cec94e07bb8 174 Gene3D G3DSA:2.30.110.10 18 149 4.0E-17 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_22185 f13f57fe7d91a23c00809cec94e07bb8 174 SUPERFAMILY SSF50475 16 127 2.14E-17 T 12-10-2018 AFR_22185 f13f57fe7d91a23c00809cec94e07bb8 174 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 25 104 7.9E-12 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_09750 297631a280085dc71e5bcfe1681b8b80 491 SUPERFAMILY SSF103473 2 446 2.49E-61 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_09750 297631a280085dc71e5bcfe1681b8b80 491 Gene3D G3DSA:1.20.1720.10 1 236 3.3E-47 T 12-10-2018 AFR_09750 297631a280085dc71e5bcfe1681b8b80 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 92 112 4.5E-5 T 12-10-2018 AFR_09750 297631a280085dc71e5bcfe1681b8b80 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 1 23 4.5E-5 T 12-10-2018 AFR_09750 297631a280085dc71e5bcfe1681b8b80 491 Gene3D G3DSA:1.20.1250.20 244 449 2.4E-18 T 12-10-2018 AFR_09750 297631a280085dc71e5bcfe1681b8b80 491 Pfam PF07690 Major Facilitator Superfamily 3 388 2.0E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_23430 140563398181c71ddfacefc944981420 721 SUPERFAMILY SSF52540 184 720 3.49E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_23430 140563398181c71ddfacefc944981420 721 Gene3D G3DSA:3.40.50.300 644 721 1.5E-7 T 12-10-2018 AFR_23430 140563398181c71ddfacefc944981420 721 Gene3D G3DSA:3.40.50.300 181 305 1.5E-7 T 12-10-2018 AFR_23430 140563398181c71ddfacefc944981420 721 Gene3D G3DSA:3.40.50.300 455 601 2.8E-7 T 12-10-2018 AFR_33405 5c37c7f8cd9cfe94c41f5650f4810361 118 SUPERFAMILY SSF55961 1 114 5.84E-21 T 12-10-2018 AFR_33405 5c37c7f8cd9cfe94c41f5650f4810361 118 Gene3D G3DSA:3.30.530.20 1 116 7.3E-22 T 12-10-2018 IPR023393 START-like domain superfamily AFR_33405 5c37c7f8cd9cfe94c41f5650f4810361 118 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 2 99 3.6E-14 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_18625 5cfa0be140aa18ecfa2ed22a0197a0bf 146 SUPERFAMILY SSF159888 43 115 1.57E-10 T 12-10-2018 AFR_18625 5cfa0be140aa18ecfa2ed22a0197a0bf 146 Pfam PF08818 Domain of unknown function (DU1801) 57 145 9.4E-9 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 AFR_27845 9b689dfe594709cdf4e1e8285929f509 281 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 43 272 5.9E-19 T 12-10-2018 IPR001087 GDSL lipase/esterase GO:0016788 AFR_27845 9b689dfe594709cdf4e1e8285929f509 281 SUPERFAMILY SSF52266 39 274 6.83E-25 T 12-10-2018 AFR_27845 9b689dfe594709cdf4e1e8285929f509 281 Gene3D G3DSA:3.40.50.1110 29 276 1.8E-25 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_03760 a65268097e65dd275507747a548b33c0 131 Gene3D G3DSA:3.30.1330.40 5 131 8.8E-27 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_03760 a65268097e65dd275507747a548b33c0 131 SUPERFAMILY SSF55298 7 130 4.87E-25 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_03760 a65268097e65dd275507747a548b33c0 131 Pfam PF01042 Endoribonuclease L-PSP 13 130 2.5E-17 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFR_15400 8a1a545da4ed0d294cce745aa939b779 127 Gene3D G3DSA:3.10.180.10 2 124 6.5E-33 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_15400 8a1a545da4ed0d294cce745aa939b779 127 SUPERFAMILY SSF54593 4 114 6.88E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_32405 2ca2d5ebeb76664963f5bdb78a4755c3 267 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 38 255 2.6E-22 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_32405 2ca2d5ebeb76664963f5bdb78a4755c3 267 SUPERFAMILY SSF52266 34 255 1.37E-57 T 12-10-2018 AFR_32405 2ca2d5ebeb76664963f5bdb78a4755c3 267 Gene3D G3DSA:3.40.50.1110 34 263 3.0E-68 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_33870 4e501de0b870217f3891fb076ff63ca2 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 318 3.7E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_37035 e02bef8802f055912e1306d44d128248 125 Pfam PF02656 Domain of unknown function (DUF202) 21 87 1.9E-13 T 12-10-2018 IPR003807 Domain of unknown function DUF202 AFR_02400 6f76bdc025716d22cf9b5599a29fffaa 376 Gene3D G3DSA:3.40.50.2000 122 363 5.8E-54 T 12-10-2018 AFR_02400 6f76bdc025716d22cf9b5599a29fffaa 376 Gene3D G3DSA:3.40.50.2000 180 351 5.8E-54 T 12-10-2018 AFR_02400 6f76bdc025716d22cf9b5599a29fffaa 376 SUPERFAMILY SSF53756 10 367 3.14E-66 T 12-10-2018 AFR_02400 6f76bdc025716d22cf9b5599a29fffaa 376 Pfam PF00534 Glycosyl transferases group 1 191 347 1.0E-40 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_23235 241b2e72a16029f28ab3188ae87573e1 331 Gene3D G3DSA:3.40.50.10440 11 184 1.1E-58 T 12-10-2018 AFR_23235 241b2e72a16029f28ab3188ae87573e1 331 SUPERFAMILY SSF82549 10 327 2.49E-108 T 12-10-2018 AFR_23235 241b2e72a16029f28ab3188ae87573e1 331 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 326 6.2E-123 T 12-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 AFR_23235 241b2e72a16029f28ab3188ae87573e1 331 Pfam PF02733 Dak1 domain 17 326 6.1E-117 T 12-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFR_23235 241b2e72a16029f28ab3188ae87573e1 331 Gene3D G3DSA:3.30.1180.20 185 329 1.3E-49 T 12-10-2018 AFR_39415 662b5c346d53d05468b33ffae27695da 238 Pfam PF09335 SNARE associated Golgi protein 31 173 4.4E-12 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_23250 8f009a07502fba87457a6da91aa50916 164 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 26 138 9.9E-14 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_23250 8f009a07502fba87457a6da91aa50916 164 Gene3D G3DSA:3.30.530.20 12 163 2.5E-28 T 12-10-2018 IPR023393 START-like domain superfamily AFR_23250 8f009a07502fba87457a6da91aa50916 164 SUPERFAMILY SSF55961 4 161 4.69E-34 T 12-10-2018 AFR_12445 798b8fd286cb59871e2248551e233160 248 SUPERFAMILY SSF53474 3 241 1.56E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_12445 798b8fd286cb59871e2248551e233160 248 Pfam PF12697 Alpha/beta hydrolase family 21 237 2.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_12445 798b8fd286cb59871e2248551e233160 248 Gene3D G3DSA:3.40.50.1820 1 246 3.2E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01145 bf55dbc41768c4eb0d7659907084805d 214 Pfam PF02469 Fasciclin domain 77 210 1.5E-12 T 12-10-2018 IPR000782 FAS1 domain AFR_01145 bf55dbc41768c4eb0d7659907084805d 214 SMART SM00554 85 211 6.0E-12 T 12-10-2018 IPR000782 FAS1 domain AFR_01145 bf55dbc41768c4eb0d7659907084805d 214 Gene3D G3DSA:2.30.180.10 18 211 3.2E-13 T 12-10-2018 IPR036378 FAS1 domain superfamily AFR_01145 bf55dbc41768c4eb0d7659907084805d 214 SUPERFAMILY SSF82153 75 211 3.01E-11 T 12-10-2018 IPR036378 FAS1 domain superfamily AFR_27000 fa6f7031e39839dafecea37cfb0c6fd5 243 Gene3D G3DSA:2.60.120.200 28 240 9.8E-13 T 12-10-2018 AFR_27000 fa6f7031e39839dafecea37cfb0c6fd5 243 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 135 238 4.8E-13 T 12-10-2018 AFR_27000 fa6f7031e39839dafecea37cfb0c6fd5 243 SUPERFAMILY SSF49899 31 239 7.64E-14 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_26850 c617f894c5107bd95831558b296a6bb9 491 SUPERFAMILY SSF55931 37 456 7.16E-55 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_26850 c617f894c5107bd95831558b296a6bb9 491 Gene3D G3DSA:3.30.590.20 40 465 1.3E-57 T 12-10-2018 AFR_26850 c617f894c5107bd95831558b296a6bb9 491 PIRSF PIRSF012666 1 491 2.9E-227 T 12-10-2018 IPR016602 Uncharacterised conserved protein UCP012666 AFR_05795 0e3e2655fbc7c26c27ee04a8ab0ff2d9 373 Gene3D G3DSA:3.40.630.30 1 188 3.6E-30 T 12-10-2018 AFR_05795 0e3e2655fbc7c26c27ee04a8ab0ff2d9 373 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 2.7E-16 T 12-10-2018 IPR000182 GNAT domain AFR_05795 0e3e2655fbc7c26c27ee04a8ab0ff2d9 373 Pfam PF13302 Acetyltransferase (GNAT) domain 205 344 2.2E-26 T 12-10-2018 IPR000182 GNAT domain AFR_05795 0e3e2655fbc7c26c27ee04a8ab0ff2d9 373 SUPERFAMILY SSF55729 198 367 8.47E-41 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05795 0e3e2655fbc7c26c27ee04a8ab0ff2d9 373 SUPERFAMILY SSF55729 5 157 1.24E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05795 0e3e2655fbc7c26c27ee04a8ab0ff2d9 373 Gene3D G3DSA:3.40.630.30 194 373 8.6E-44 T 12-10-2018 AFR_37850 2734870852c95332cd477e194794ca3f 446 SUPERFAMILY SSF88713 237 423 2.11E-50 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_37850 2734870852c95332cd477e194794ca3f 446 Gene3D G3DSA:3.20.20.370 220 425 7.5E-55 T 12-10-2018 AFR_37850 2734870852c95332cd477e194794ca3f 446 Pfam PF01522 Polysaccharide deacetylase 239 359 6.3E-29 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_15120 e155edc1c09695162e566fce21abccf7 115 SUPERFAMILY SSF46785 4 110 1.05E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_15120 e155edc1c09695162e566fce21abccf7 115 Pfam PF01638 HxlR-like helix-turn-helix 16 104 8.1E-25 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_15120 e155edc1c09695162e566fce21abccf7 115 Gene3D G3DSA:1.10.10.10 1 115 6.3E-41 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_02760 2bc310d3e79b05407ad625ec128ad39e 366 Gene3D G3DSA:3.40.710.30 8 366 5.9E-84 T 12-10-2018 AFR_02760 2bc310d3e79b05407ad625ec128ad39e 366 Pfam PF00144 Beta-lactamase 11 359 2.4E-49 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_02760 2bc310d3e79b05407ad625ec128ad39e 366 SUPERFAMILY SSF56601 5 358 2.81E-55 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_28580 4f9c9e1e985b1548ed9bbe08adf37c07 292 SUPERFAMILY SSF53474 41 284 2.81E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28580 4f9c9e1e985b1548ed9bbe08adf37c07 292 Gene3D G3DSA:3.40.50.1820 5 287 1.1E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28580 4f9c9e1e985b1548ed9bbe08adf37c07 292 Pfam PF12697 Alpha/beta hydrolase family 56 279 2.5E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_40110 788e420d6888cc557396621a3166dce7 165 SUPERFAMILY SSF55961 20 160 7.46E-18 T 12-10-2018 AFR_40110 788e420d6888cc557396621a3166dce7 165 Gene3D G3DSA:3.30.530.20 17 163 1.5E-14 T 12-10-2018 IPR023393 START-like domain superfamily AFR_40110 788e420d6888cc557396621a3166dce7 165 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 19 160 4.2E-11 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_13165 bb36ae39bf4e84c3a40091222f877dc4 279 Pfam PF13560 Helix-turn-helix domain 5 83 2.8E-16 T 12-10-2018 AFR_13165 bb36ae39bf4e84c3a40091222f877dc4 279 Gene3D G3DSA:1.10.260.40 27 93 4.1E-7 T 12-10-2018 AFR_13165 bb36ae39bf4e84c3a40091222f877dc4 279 SUPERFAMILY SSF47413 29 80 5.91E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_13165 bb36ae39bf4e84c3a40091222f877dc4 279 SMART SM00530 9 81 3.5E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_21315 cf84be044634cdaafd966828069cbe15 300 Pfam PF12294 Protein of unknown function (DUF3626) 26 277 2.0E-83 T 12-10-2018 IPR022074 Protein of unknown function DUF3626 AFR_18495 f08c7caccbb6a01351339399fb644a25 302 Gene3D G3DSA:3.30.230.10 54 155 1.3E-9 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFR_18495 f08c7caccbb6a01351339399fb644a25 302 SUPERFAMILY SSF54211 19 173 2.88E-17 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFR_18495 f08c7caccbb6a01351339399fb644a25 302 Pfam PF00288 GHMP kinases N terminal domain 93 127 1.8E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFR_18495 f08c7caccbb6a01351339399fb644a25 302 Pfam PF08544 GHMP kinases C terminal 211 273 8.3E-6 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain AFR_18495 f08c7caccbb6a01351339399fb644a25 302 PIRSF PIRSF033887 1 300 1.1E-112 T 12-10-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 AFR_19465 165892c98536d802ec021f2b915afc32 228 Pfam PF04892 VanZ like family 101 205 2.2E-13 T 12-10-2018 IPR006976 VanZ-like AFR_27700 c72c2a1cb8e452663b5ef0877c85ea8d 468 SUPERFAMILY SSF53335 168 420 1.17E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_37045 84a5fffe4bc93d8ff3efc2e775dcf8c5 112 Pfam PF13396 Phospholipase_D-nuclease N-terminal 14 57 1.5E-11 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal AFR_32650 d24c1ff8825d24301c27356dde6771fd 259 SUPERFAMILY SSF56219 3 259 4.71E-32 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_32650 d24c1ff8825d24301c27356dde6771fd 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 250 3.2E-14 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_32650 d24c1ff8825d24301c27356dde6771fd 259 Gene3D G3DSA:3.60.10.10 2 259 4.7E-36 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_42700 2c7d8f96d6b573a0a44ae753e2a95a65 400 SUPERFAMILY SSF52540 6 288 2.54E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42700 2c7d8f96d6b573a0a44ae753e2a95a65 400 Gene3D G3DSA:3.40.50.300 11 231 2.1E-7 T 12-10-2018 AFR_42700 2c7d8f96d6b573a0a44ae753e2a95a65 400 Pfam PF13191 AAA ATPase domain 19 209 6.0E-23 T 12-10-2018 AFR_33210 88386c9fc32429bdace0fd15e33fd177 167 Gene3D G3DSA:1.20.120.450 1 167 6.3E-60 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_33210 88386c9fc32429bdace0fd15e33fd177 167 SUPERFAMILY SSF109854 5 166 2.44E-32 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_33210 88386c9fc32429bdace0fd15e33fd177 167 Pfam PF04978 Protein of unknown function (DUF664) 18 165 1.6E-17 T 12-10-2018 IPR007061 Protein of unknown function DUF664 AFR_01000 468124ae48191c82a000761e17d59973 288 SUPERFAMILY SSF56112 27 228 3.64E-10 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_08155 8c2f16d3e2387b46f9c1980ee9b38c53 120 Gene3D G3DSA:3.10.180.10 2 120 2.3E-34 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_08155 8c2f16d3e2387b46f9c1980ee9b38c53 120 SUPERFAMILY SSF54593 1 113 4.13E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_15095 7056186d68408ee13eae8ce5133d7e47 310 Gene3D G3DSA:3.90.245.10 1 305 2.3E-115 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like AFR_15095 7056186d68408ee13eae8ce5133d7e47 310 SUPERFAMILY SSF53590 1 303 1.14E-99 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like AFR_15095 7056186d68408ee13eae8ce5133d7e47 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 1 296 5.1E-93 T 12-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain AFR_09220 754e71d70a4e06fc7a9e224481a3c251 148 Pfam PF08592 Domain of unknown function (DUF1772) 18 146 1.9E-16 T 12-10-2018 AFR_03350 73c0d99c236d41a97edeb15e439d0ced 107 Gene3D G3DSA:3.30.70.1060 1 107 2.3E-31 T 12-10-2018 AFR_03350 73c0d99c236d41a97edeb15e439d0ced 107 SUPERFAMILY SSF54909 1 106 5.9E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_03350 73c0d99c236d41a97edeb15e439d0ced 107 Pfam PF03795 YCII-related domain 1 105 5.2E-14 T 12-10-2018 IPR005545 YCII-related AFR_36795 b3c88d1280c10c0bfbbc00015bde353a 339 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 2.5E-59 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFR_36795 b3c88d1280c10c0bfbbc00015bde353a 339 Gene3D G3DSA:1.10.8.300 202 319 1.3E-33 T 12-10-2018 AFR_36795 b3c88d1280c10c0bfbbc00015bde353a 339 SUPERFAMILY SSF52540 21 294 4.62E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_36795 b3c88d1280c10c0bfbbc00015bde353a 339 PIRSF PIRSF002849 2 324 2.4E-127 T 12-10-2018 AFR_36795 b3c88d1280c10c0bfbbc00015bde353a 339 Gene3D G3DSA:3.40.50.300 7 193 3.8E-48 T 12-10-2018 AFR_14005 573d9ddf86ffceb2162d3e153693cd3a 287 Gene3D G3DSA:1.10.10.1550 44 94 2.6E-6 T 12-10-2018 AFR_14005 573d9ddf86ffceb2162d3e153693cd3a 287 Pfam PF05443 ROS/MUCR transcriptional regulator protein 53 105 3.3E-6 T 12-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 AFR_29545 f6f35bba63d953da6012d0123ae249c0 129 SUPERFAMILY SSF88659 92 129 1.55E-5 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_29545 f6f35bba63d953da6012d0123ae249c0 129 Gene3D G3DSA:1.10.10.10 76 129 2.3E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_29545 f6f35bba63d953da6012d0123ae249c0 129 SUPERFAMILY SSF88946 4 90 7.46E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_29545 f6f35bba63d953da6012d0123ae249c0 129 Pfam PF04542 Sigma-70 region 2 18 76 7.2E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_16985 ce3f48bb340a91ee89c4e8a19f3352d6 496 SUPERFAMILY SSF75005 271 484 3.77E-48 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_16985 ce3f48bb340a91ee89c4e8a19f3352d6 496 Gene3D G3DSA:2.115.10.20 242 496 2.4E-55 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFR_16985 ce3f48bb340a91ee89c4e8a19f3352d6 496 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 267 491 1.1E-23 T 12-10-2018 IPR007184 Mannoside phosphorylase AFR_11100 1a6a006bcd3a7701983dd30a6e7825d2 261 Pfam PF11296 Protein of unknown function (DUF3097) 5 259 2.7E-119 T 12-10-2018 IPR021447 Protein of unknown function DUF3097 AFR_17765 af73c86b79fedb1db1ed6b84fd90a300 207 Gene3D G3DSA:1.20.120.450 2 159 1.1E-11 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_17765 af73c86b79fedb1db1ed6b84fd90a300 207 SUPERFAMILY SSF109854 3 161 2.75E-11 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_17765 af73c86b79fedb1db1ed6b84fd90a300 207 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 156 6.5E-16 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_02240 ef4b8a7d75f1db2bc3cc3c9260bfca84 63 Pfam PF04024 PspC domain 6 62 2.2E-19 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal AFR_03595 6ceb6d9389d04f0fbb186548011f6ef3 194 SUPERFAMILY SSF53335 12 165 1.05E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_03595 6ceb6d9389d04f0fbb186548011f6ef3 194 Pfam PF13649 Methyltransferase domain 50 139 9.2E-15 T 12-10-2018 AFR_03595 6ceb6d9389d04f0fbb186548011f6ef3 194 Gene3D G3DSA:3.40.50.150 2 193 1.6E-49 T 12-10-2018 AFR_38605 089a65d3c4d24f2462d8b9920d2844c1 241 SUPERFAMILY SSF53335 43 204 1.07E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_38605 089a65d3c4d24f2462d8b9920d2844c1 241 Gene3D G3DSA:3.40.50.150 42 241 1.0E-13 T 12-10-2018 AFR_15105 82ae53f199d7bcc39f1bfa8500cdae82 325 Gene3D G3DSA:3.20.20.100 1 323 1.4E-116 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_15105 82ae53f199d7bcc39f1bfa8500cdae82 325 Pfam PF00248 Aldo/keto reductase family 13 306 2.8E-75 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_15105 82ae53f199d7bcc39f1bfa8500cdae82 325 SUPERFAMILY SSF51430 7 307 6.29E-98 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_16590 60aaba04dc981bbcb08de4d17f4fe8db 204 Gene3D G3DSA:3.40.50.10490 3 193 2.9E-62 T 12-10-2018 AFR_16590 60aaba04dc981bbcb08de4d17f4fe8db 204 SUPERFAMILY SSF53697 9 188 1.07E-45 T 12-10-2018 AFR_16590 60aaba04dc981bbcb08de4d17f4fe8db 204 Pfam PF13580 SIS domain 25 146 1.2E-25 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFR_04840 efa0866e072a9311b4fa841597a61354 364 SUPERFAMILY SSF53474 65 361 2.9E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_04840 efa0866e072a9311b4fa841597a61354 364 Pfam PF00561 alpha/beta hydrolase fold 93 348 4.4E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_04840 efa0866e072a9311b4fa841597a61354 364 Gene3D G3DSA:3.40.50.1820 64 363 1.3E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_18315 19e6f4b475c456270d6ca5ce23934be3 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 276 3.4E-28 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_14785 0e8aeec1e8cc54552902a1e5b69f714c 271 Gene3D G3DSA:1.10.3720.10 3 261 1.7E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14785 0e8aeec1e8cc54552902a1e5b69f714c 271 SUPERFAMILY SSF161098 4 267 5.01E-68 T 12-10-2018 IPR035906 MetI-like superfamily AFR_14785 0e8aeec1e8cc54552902a1e5b69f714c 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 254 8.9E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30985 248a373314d31b78a501768404fed461 363 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 23 332 7.1E-122 T 12-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC AFR_30985 248a373314d31b78a501768404fed461 363 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 322 4.2E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_21355 c11345542a972efd1863d0ba40208c8d 118 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 5.9E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_21355 c11345542a972efd1863d0ba40208c8d 118 SUPERFAMILY SSF46785 6 80 1.43E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_21355 c11345542a972efd1863d0ba40208c8d 118 SMART SM00345 17 76 6.0E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFR_21355 c11345542a972efd1863d0ba40208c8d 118 Gene3D G3DSA:1.10.10.10 9 117 1.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05495 db0e55f9fe93133cc30180ebc6c52259 219 SUPERFAMILY SSF55068 8 212 7.72E-81 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_05495 db0e55f9fe93133cc30180ebc6c52259 219 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 46 202 3.1E-66 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_05495 db0e55f9fe93133cc30180ebc6c52259 219 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 45 208 37.22 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_05495 db0e55f9fe93133cc30180ebc6c52259 219 Gene3D G3DSA:3.30.1060.10 5 217 9.0E-94 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_05495 db0e55f9fe93133cc30180ebc6c52259 219 Pfam PF01625 Peptide methionine sulfoxide reductase 47 202 2.0E-68 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 Gene3D G3DSA:3.40.50.720 1 217 6.7E-46 T 12-10-2018 AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 SUPERFAMILY SSF51735 1 200 3.87E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 4.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 4.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 4.9E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 1.5E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 126 1.5E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 157 1.5E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14725 6977ab8fc1e8705d08f2812bfb4a31c6 225 Pfam PF00106 short chain dehydrogenase 7 177 3.7E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_14240 84b406dbf338f5665beb3fc234086102 85 Pfam PF04075 F420H(2)-dependent quinone reductase 2 77 1.9E-9 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_14240 84b406dbf338f5665beb3fc234086102 85 Gene3D G3DSA:2.30.110.10 1 81 6.9E-17 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_24500 7837b7dc552bcab260c9570b1975b065 167 Gene3D G3DSA:3.20.80.10 1 164 3.7E-10 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_24500 7837b7dc552bcab260c9570b1975b065 167 SUPERFAMILY SSF55136 55 161 3.4E-5 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFR_38060 58c4329e74a54969a5c95b6785eaeff5 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 17.822 T 12-10-2018 IPR003482 Transcription factor WhiB AFR_38060 58c4329e74a54969a5c95b6785eaeff5 84 Pfam PF02467 Transcription factor WhiB 3 70 3.4E-25 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain AFR_42055 356124ad5d18d6cbfa2df89d549ed98d 270 PIRSF PIRSF017393 1 270 4.1E-103 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_42055 356124ad5d18d6cbfa2df89d549ed98d 270 Pfam PF04672 S-adenosyl methyltransferase 11 270 4.6E-104 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type AFR_42055 356124ad5d18d6cbfa2df89d549ed98d 270 Gene3D G3DSA:3.40.50.150 1 270 1.2E-108 T 12-10-2018 AFR_42055 356124ad5d18d6cbfa2df89d549ed98d 270 SUPERFAMILY SSF53335 18 258 7.38E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_22330 6ef78c094fd48206fec6ee7690bd628b 114 Pfam PF13187 4Fe-4S dicluster domain 9 55 5.2E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFR_22330 6ef78c094fd48206fec6ee7690bd628b 114 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_22330 6ef78c094fd48206fec6ee7690bd628b 114 SUPERFAMILY SSF54862 5 68 2.19E-17 T 12-10-2018 AFR_22330 6ef78c094fd48206fec6ee7690bd628b 114 Gene3D G3DSA:3.30.70.20 3 67 4.0E-12 T 12-10-2018 AFR_22330 6ef78c094fd48206fec6ee7690bd628b 114 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFR_31485 2677d33c3f307532b7b220c97533d1ef 364 SUPERFAMILY SSF53335 5 172 6.72E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_31485 2677d33c3f307532b7b220c97533d1ef 364 Gene3D G3DSA:3.40.50.150 5 202 6.9E-43 T 12-10-2018 AFR_31485 2677d33c3f307532b7b220c97533d1ef 364 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 55 202 2.4E-22 T 12-10-2018 AFR_08520 19a097b80b04640faedef08b51578709 331 Pfam PF01944 Stage II sporulation protein M 107 280 3.3E-31 T 12-10-2018 IPR002798 Stage II sporulation protein M-like AFR_24945 014a4efc781481f9a531970a47bcba6f 411 Pfam PF07478 D-ala D-ala ligase C-terminus 144 186 1.3E-4 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFR_24945 014a4efc781481f9a531970a47bcba6f 411 Gene3D G3DSA:3.30.1490.20 133 188 6.6E-9 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFR_24945 014a4efc781481f9a531970a47bcba6f 411 SUPERFAMILY SSF56059 101 212 9.43E-10 T 12-10-2018 AFR_37880 e176611be5df72015b18831bc7a8a3af 381 SUPERFAMILY SSF49879 235 347 5.18E-9 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 AFR_37880 e176611be5df72015b18831bc7a8a3af 381 Gene3D G3DSA:2.60.200.20 226 351 1.0E-7 T 12-10-2018 AFR_17995 125d9bc504b261f4770d33c8e9cb6879 302 Gene3D G3DSA:1.10.3720.10 26 290 2.0E-55 T 12-10-2018 IPR035906 MetI-like superfamily AFR_17995 125d9bc504b261f4770d33c8e9cb6879 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 285 1.4E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_17995 125d9bc504b261f4770d33c8e9cb6879 302 SUPERFAMILY SSF161098 31 299 1.4E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_07725 633f16498ad9356017a1de5f9d825760 133 SUPERFAMILY SSF81301 8 118 1.32E-35 T 12-10-2018 AFR_07725 633f16498ad9356017a1de5f9d825760 133 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 111 22.498 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFR_07725 633f16498ad9356017a1de5f9d825760 133 Pfam PF02410 Ribosomal silencing factor during starvation 14 110 2.7E-23 T 12-10-2018 AFR_07725 633f16498ad9356017a1de5f9d825760 133 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 13 110 5.7E-31 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFR_07725 633f16498ad9356017a1de5f9d825760 133 Gene3D G3DSA:3.30.460.10 2 114 4.3E-37 T 12-10-2018 AFR_06840 a58d2872d488f822099ef5af6641fa98 206 Pfam PF09997 Predicted membrane protein (DUF2238) 40 180 8.1E-57 T 12-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 AFR_06840 a58d2872d488f822099ef5af6641fa98 206 PIRSF PIRSF020606 1 202 1.1E-69 T 12-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 AFR_38235 632a2903168eb8ee0d07126de47b01ef 872 Pfam PF14765 Polyketide synthase dehydratase 731 859 8.3E-7 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_38235 632a2903168eb8ee0d07126de47b01ef 872 Pfam PF14765 Polyketide synthase dehydratase 622 685 5.0E-7 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFR_38235 632a2903168eb8ee0d07126de47b01ef 872 Gene3D G3DSA:3.10.129.110 621 854 3.0E-17 T 12-10-2018 AFR_38235 632a2903168eb8ee0d07126de47b01ef 872 Gene3D G3DSA:3.40.50.720 291 571 2.9E-6 T 12-10-2018 AFR_33600 a863908349e0a154ce40a2b22325295f 82 Pfam PF14026 Protein of unknown function (DUF4242) 4 77 2.4E-21 T 12-10-2018 IPR025336 Protein of unknown function DUF4242 AFR_33600 a863908349e0a154ce40a2b22325295f 82 Gene3D G3DSA:3.30.70.3090 1 80 1.1E-28 T 12-10-2018 AFR_06310 7078bd2b572c9d3b3e1c07a015c1e472 191 Pfam PF00857 Isochorismatase family 4 179 1.6E-29 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_06310 7078bd2b572c9d3b3e1c07a015c1e472 191 SUPERFAMILY SSF52499 2 182 8.37E-44 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_06310 7078bd2b572c9d3b3e1c07a015c1e472 191 Gene3D G3DSA:3.40.50.850 2 183 8.7E-59 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_20800 982c76b11fbffc9ba4f5add59118471b 246 Gene3D G3DSA:3.90.226.10 2 246 2.0E-67 T 12-10-2018 AFR_20800 982c76b11fbffc9ba4f5add59118471b 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 208 9.1E-49 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFR_20800 982c76b11fbffc9ba4f5add59118471b 246 SUPERFAMILY SSF52096 4 242 5.86E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFR_13975 104e593cd15beccb98166e8b5c2d06ef 133 Pfam PF00188 Cysteine-rich secretory protein family 16 131 1.4E-22 T 12-10-2018 IPR014044 CAP domain AFR_13975 104e593cd15beccb98166e8b5c2d06ef 133 SUPERFAMILY SSF55797 8 132 3.4E-25 T 12-10-2018 IPR035940 CAP superfamily AFR_13975 104e593cd15beccb98166e8b5c2d06ef 133 Gene3D G3DSA:3.40.33.10 3 132 1.4E-50 T 12-10-2018 IPR035940 CAP superfamily AFR_25630 a97709e05a62aa405d511feba3b0fdde 292 Gene3D G3DSA:3.40.33.10 89 289 6.2E-49 T 12-10-2018 IPR035940 CAP superfamily AFR_25630 a97709e05a62aa405d511feba3b0fdde 292 SUPERFAMILY SSF55797 165 289 2.01E-23 T 12-10-2018 IPR035940 CAP superfamily AFR_25630 a97709e05a62aa405d511feba3b0fdde 292 Pfam PF00188 Cysteine-rich secretory protein family 172 288 1.3E-20 T 12-10-2018 IPR014044 CAP domain AFR_06645 ef28a8156da0fec1dbcaced10a3bdf10 287 SUPERFAMILY SSF161098 9 277 2.06E-45 T 12-10-2018 IPR035906 MetI-like superfamily AFR_06645 ef28a8156da0fec1dbcaced10a3bdf10 287 Gene3D G3DSA:1.10.3720.10 6 285 7.7E-44 T 12-10-2018 IPR035906 MetI-like superfamily AFR_06645 ef28a8156da0fec1dbcaced10a3bdf10 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 269 6.5E-7 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_26635 2647bf3c203e12059aea8a7dcf7dadfd 264 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 11 264 4.8E-109 T 12-10-2018 IPR022292 Conserved hypothetical protein CHP03843 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 Gene3D G3DSA:3.40.630.10 95 425 2.8E-75 T 12-10-2018 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 Pfam PF00246 Zinc carboxypeptidase 111 374 7.0E-58 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 155 169 1.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 240 248 1.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 128 140 1.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 294 307 1.3E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 SMART SM00631 102 380 7.1E-63 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 Pfam PF05547 Immune inhibitor A peptidase M6 767 946 4.4E-18 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_31740 ec8211b6f1d645060ac34f6fabd9d18c 1004 SUPERFAMILY SSF53187 98 384 5.94E-68 T 12-10-2018 AFR_21890 9048dfc1057520624887aa6fea3c11ed 212 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 2.2E-17 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFR_21890 9048dfc1057520624887aa6fea3c11ed 212 SUPERFAMILY SSF51735 1 201 1.53E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_21890 9048dfc1057520624887aa6fea3c11ed 212 Gene3D G3DSA:3.40.50.720 1 201 2.0E-52 T 12-10-2018 AFR_40070 eaf745d11fc1fe977cd0b7a55d409d0d 233 Pfam PF01596 O-methyltransferase 55 226 4.5E-22 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 AFR_40070 eaf745d11fc1fe977cd0b7a55d409d0d 233 SUPERFAMILY SSF53335 56 233 6.11E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_40070 eaf745d11fc1fe977cd0b7a55d409d0d 233 Gene3D G3DSA:3.40.50.150 27 233 8.8E-56 T 12-10-2018 AFR_00620 13623f74ebcb0fad037174c593f08d32 344 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 110 253 6.3E-24 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_00620 13623f74ebcb0fad037174c593f08d32 344 Gene3D G3DSA:1.10.260.150 79 315 4.1E-44 T 12-10-2018 AFR_00620 13623f74ebcb0fad037174c593f08d32 344 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 110 253 9.3E-25 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_12210 568db0b3eaa9df4f82134287001bfee2 306 Gene3D G3DSA:2.60.40.2880 206 302 1.8E-5 T 12-10-2018 IPR038468 Transport accessory protein MmpS, soluble domain superfamily AFR_06385 856cf663ecf63b417683a154d17b7cbc 302 Gene3D G3DSA:3.40.50.300 1 228 3.3E-58 T 12-10-2018 AFR_06385 856cf663ecf63b417683a154d17b7cbc 302 SUPERFAMILY SSF52540 4 220 2.27E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06385 856cf663ecf63b417683a154d17b7cbc 302 Pfam PF00005 ABC transporter 20 158 1.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_06385 856cf663ecf63b417683a154d17b7cbc 302 SMART SM00382 28 206 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SMART SM00710 339 381 3000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SMART SM00710 467 491 590.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SMART SM00710 416 438 290.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SMART SM00710 499 530 2200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SMART SM00710 392 414 1400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SMART SM00710 443 466 270.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SMART SM00710 287 331 3100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 Pfam PF12708 Pectate lyase superfamily protein 245 473 1.4E-17 T 12-10-2018 IPR024535 Pectate lyase superfamily protein AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 Gene3D G3DSA:2.160.20.10 244 543 1.1E-37 T 12-10-2018 IPR012334 Pectin lyase fold AFR_03530 a7a23a0b5e35d8dcddfdfc5527527fca 668 SUPERFAMILY SSF51126 242 585 1.95E-34 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_09200 b0e381ac0d976be193afaa18c13096de 107 SUPERFAMILY SSF54909 1 95 6.43E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_09200 b0e381ac0d976be193afaa18c13096de 107 Gene3D G3DSA:3.30.70.1060 1 104 1.5E-23 T 12-10-2018 AFR_09200 b0e381ac0d976be193afaa18c13096de 107 Pfam PF03795 YCII-related domain 1 90 9.5E-16 T 12-10-2018 IPR005545 YCII-related AFR_23580 b8a874464479cf294bf637b2c9badb43 380 ProSitePatterns PS01043 Transposases, IS30 family, signature. 320 336 - T 12-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 AFR_23580 b8a874464479cf294bf637b2c9badb43 380 Pfam PF13936 Helix-turn-helix domain 52 93 1.6E-14 T 12-10-2018 IPR025246 Transposase IS30-like HTH domain AFR_23580 b8a874464479cf294bf637b2c9badb43 380 Pfam PF00665 Integrase core domain 227 333 4.3E-13 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFR_23580 b8a874464479cf294bf637b2c9badb43 380 SUPERFAMILY SSF53098 227 376 1.97E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_17000 9e77864200edc30bff3ea3876424ebc4 419 Pfam PF00155 Aminotransferase class I and II 48 401 7.8E-34 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_17000 9e77864200edc30bff3ea3876424ebc4 419 SUPERFAMILY SSF53383 30 403 1.12E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_17000 9e77864200edc30bff3ea3876424ebc4 419 Gene3D G3DSA:3.90.1150.10 40 402 2.7E-93 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_17000 9e77864200edc30bff3ea3876424ebc4 419 Gene3D G3DSA:3.40.640.10 61 310 2.7E-93 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_33380 3d96342b136ce5273b347a911e2a68c5 168 Pfam PF04978 Protein of unknown function (DUF664) 18 164 3.6E-43 T 12-10-2018 IPR007061 Protein of unknown function DUF664 AFR_33380 3d96342b136ce5273b347a911e2a68c5 168 Gene3D G3DSA:1.20.120.450 10 165 2.3E-31 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_33380 3d96342b136ce5273b347a911e2a68c5 168 SUPERFAMILY SSF109854 3 163 1.04E-38 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_28295 0c5d6f6791dd2ba3c8656dd9b1855cce 406 Pfam PF13360 PQQ-like domain 98 221 1.6E-8 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_28295 0c5d6f6791dd2ba3c8656dd9b1855cce 406 SUPERFAMILY SSF50998 45 339 1.1E-12 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_18655 009214a8249d5dd1b60b6ac93363672f 124 Pfam PF13564 DoxX-like family 7 114 4.0E-26 T 12-10-2018 IPR032808 DoxX family AFR_24720 163d66e4bf862266056925ebf5e59a82 168 Gene3D G3DSA:3.40.50.300 1 168 1.3E-44 T 12-10-2018 AFR_24720 163d66e4bf862266056925ebf5e59a82 168 Pfam PF13671 AAA domain 3 136 1.2E-10 T 12-10-2018 AFR_24720 163d66e4bf862266056925ebf5e59a82 168 SUPERFAMILY SSF52540 3 166 2.71E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24605 8fa58ad846132f152a8aa13ce3963b51 498 Pfam PF07519 Tannase and feruloyl esterase 56 455 3.0E-82 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 AFR_24605 8fa58ad846132f152a8aa13ce3963b51 498 SUPERFAMILY SSF53474 155 425 1.19E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 SUPERFAMILY SSF56042 168 313 1.64E-34 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 Gene3D G3DSA:3.90.650.10 168 328 1.1E-39 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 Gene3D G3DSA:3.30.1330.10 1 167 2.0E-46 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 54 160 1.8E-17 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 TIGRFAM TIGR00476 selD: selenide, water dikinase 8 313 2.0E-113 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 SUPERFAMILY SSF55326 9 165 8.97E-37 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 PIRSF PIRSF036407 2 316 7.1E-98 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 Hamap MF_00625 Selenide, water dikinase [selD]. 6 336 36.139 T 12-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 AFR_27955 e35dadf06ec36e80ade606e5d7a749a0 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 311 6.1E-16 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFR_18515 f35197712733b7a7532547bc0dfb2fbc 145 Gene3D G3DSA:3.40.50.280 8 144 1.1E-24 T 12-10-2018 AFR_18515 f35197712733b7a7532547bc0dfb2fbc 145 SUPERFAMILY SSF52242 11 129 2.83E-20 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_18515 f35197712733b7a7532547bc0dfb2fbc 145 Pfam PF02310 B12 binding domain 12 102 1.2E-12 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFR_25415 02d6a89ce1fe53b505ff5b2ae08e58cc 65 SUPERFAMILY SSF55174 2 64 4.84E-20 T 12-10-2018 AFR_25415 02d6a89ce1fe53b505ff5b2ae08e58cc 65 Gene3D G3DSA:3.10.290.10 1 65 1.9E-25 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFR_25415 02d6a89ce1fe53b505ff5b2ae08e58cc 65 Pfam PF13275 S4 domain 2 64 6.1E-28 T 12-10-2018 AFR_02800 ed22a28555d1d15fcb7f213c19d780ec 155 Pfam PF13302 Acetyltransferase (GNAT) domain 1 130 9.6E-7 T 12-10-2018 IPR000182 GNAT domain AFR_02800 ed22a28555d1d15fcb7f213c19d780ec 155 SUPERFAMILY SSF55729 2 136 3.4E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_02800 ed22a28555d1d15fcb7f213c19d780ec 155 Gene3D G3DSA:3.40.630.30 1 151 1.6E-16 T 12-10-2018 AFR_40650 86e2b289c91bad0f9485f0540ca0f77c 343 Gene3D G3DSA:2.60.40.10 38 134 1.0E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_40650 86e2b289c91bad0f9485f0540ca0f77c 343 SUPERFAMILY SSF49299 42 115 1.83E-6 T 12-10-2018 IPR035986 PKD domain superfamily AFR_00275 42ae33f526be38f6796924e44b97d914 475 SUPERFAMILY SSF81606 4 235 6.41E-64 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_00275 42ae33f526be38f6796924e44b97d914 475 SMART SM00332 2 234 2.7E-26 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_00275 42ae33f526be38f6796924e44b97d914 475 Pfam PF13672 Protein phosphatase 2C 20 205 3.0E-13 T 12-10-2018 AFR_00275 42ae33f526be38f6796924e44b97d914 475 Gene3D G3DSA:3.60.40.10 2 236 1.4E-65 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_00275 42ae33f526be38f6796924e44b97d914 475 SMART SM00331 11 236 1.5E-35 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_23755 9c63b2a2f6c352454086b732d29ad7c2 254 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 91 250 1.5E-16 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFR_23755 9c63b2a2f6c352454086b732d29ad7c2 254 SUPERFAMILY SSF56529 2 250 2.62E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_23755 9c63b2a2f6c352454086b732d29ad7c2 254 Gene3D G3DSA:3.90.850.10 1 252 4.7E-81 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFR_04935 8a727841a7511efd64c64f075e0404ff 129 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 101 17.966 T 12-10-2018 IPR003482 Transcription factor WhiB AFR_04935 8a727841a7511efd64c64f075e0404ff 129 Pfam PF02467 Transcription factor WhiB 17 87 2.0E-21 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain AFR_34905 70f20ad3ef3816664d2c99e737c0e96e 75 SUPERFAMILY SSF46785 1 67 3.11E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_34905 70f20ad3ef3816664d2c99e737c0e96e 75 Pfam PF01022 Bacterial regulatory protein, arsR family 1 29 4.1E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_34905 70f20ad3ef3816664d2c99e737c0e96e 75 Gene3D G3DSA:1.10.10.10 1 73 5.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_08915 28c17383159b8f76b12f6384cb5ae243 548 Pfam PF00474 Sodium:solute symporter family 42 446 4.3E-21 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFR_08915 28c17383159b8f76b12f6384cb5ae243 548 Gene3D G3DSA:1.20.1730.10 31 524 7.2E-37 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily AFR_11745 e353fb47f3a2a95740347f456015fa01 200 Gene3D G3DSA:3.10.180.10 59 193 1.7E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_11745 e353fb47f3a2a95740347f456015fa01 200 SUPERFAMILY SSF54593 75 189 1.4E-14 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_28560 a7a6ffc9ca036e62b519d9ec2fc11121 157 Pfam PF07366 SnoaL-like polyketide cyclase 5 133 3.4E-20 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 AFR_28560 a7a6ffc9ca036e62b519d9ec2fc11121 157 Gene3D G3DSA:3.10.450.50 1 140 1.4E-27 T 12-10-2018 AFR_28560 a7a6ffc9ca036e62b519d9ec2fc11121 157 SUPERFAMILY SSF54427 4 140 1.46E-24 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_40160 a7ad4d36c69d66a25dd46564e2137004 321 SUPERFAMILY SSF55729 10 126 2.27E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40160 a7ad4d36c69d66a25dd46564e2137004 321 Gene3D G3DSA:3.40.630.30 1 312 2.7E-65 T 12-10-2018 AFR_40160 a7ad4d36c69d66a25dd46564e2137004 321 SUPERFAMILY SSF55729 190 307 2.13E-7 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_40160 a7ad4d36c69d66a25dd46564e2137004 321 Pfam PF13508 Acetyltransferase (GNAT) domain 38 121 4.6E-11 T 12-10-2018 IPR000182 GNAT domain AFR_09475 166eb1bb226cc4f24fe692e61558d050 492 Pfam PF05991 YacP-like NYN domain 372 491 5.0E-20 T 12-10-2018 IPR010298 Protein of unknown function DUF901 AFR_14805 f0469df8134a5a0b8ead686779316368 398 Pfam PF07730 Histidine kinase 193 259 3.6E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_14805 f0469df8134a5a0b8ead686779316368 398 SUPERFAMILY SSF55874 298 389 7.34E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_14805 f0469df8134a5a0b8ead686779316368 398 Gene3D G3DSA:3.30.565.10 271 390 7.2E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21885 83ba4950d7dec1452a625cb1da817d8a 221 Pfam PF02230 Phospholipase/Carboxylesterase 110 215 2.0E-8 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 AFR_21885 83ba4950d7dec1452a625cb1da817d8a 221 SUPERFAMILY SSF53474 31 217 1.54E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21885 83ba4950d7dec1452a625cb1da817d8a 221 Gene3D G3DSA:3.40.50.1820 28 219 5.9E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13565 9e3585b11bedc6da1bdd3096d7ce464a 97 Pfam PF11239 Protein of unknown function (DUF3040) 1 76 8.2E-10 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 AFR_02720 5b7fbdb41f73be27c2b33df3335bc10b 327 Gene3D G3DSA:3.90.550.10 2 218 1.3E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02720 5b7fbdb41f73be27c2b33df3335bc10b 327 Pfam PF00535 Glycosyl transferase family 2 7 169 2.7E-33 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_02720 5b7fbdb41f73be27c2b33df3335bc10b 327 SUPERFAMILY SSF53448 6 181 3.85E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_05350 1ad1bfb29cc341633edf31bf77d5f28a 109 SUPERFAMILY SSF46785 11 105 4.33E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_05350 1ad1bfb29cc341633edf31bf77d5f28a 109 Pfam PF03551 Transcriptional regulator PadR-like family 16 86 5.8E-18 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_05350 1ad1bfb29cc341633edf31bf77d5f28a 109 Gene3D G3DSA:1.10.10.10 2 109 3.0E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_25505 0ef71416430b90ed0ee526c76d42ffdb 514 Pfam PF08811 Protein of unknown function (DUF1800) 55 513 3.7E-116 T 12-10-2018 IPR014917 Protein of unknown function DUF1800 AFR_03240 7c55f5ef759de0d5ba0f9673dfc94968 388 Pfam PF06134 L-rhamnose isomerase (RhaA) 80 336 5.4E-7 T 12-10-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 AFR_03240 7c55f5ef759de0d5ba0f9673dfc94968 388 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 5 378 3.5E-191 T 12-10-2018 IPR013457 Rhamnose isomerase-related AFR_03240 7c55f5ef759de0d5ba0f9673dfc94968 388 Gene3D G3DSA:3.20.20.150 2 380 1.5E-127 T 12-10-2018 AFR_03240 7c55f5ef759de0d5ba0f9673dfc94968 388 SUPERFAMILY SSF51658 25 357 2.76E-92 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_34940 fc76a5e22120f4d66e780ad1988bca37 253 SUPERFAMILY SSF55021 3 70 3.62E-7 T 12-10-2018 AFR_34940 fc76a5e22120f4d66e780ad1988bca37 253 Gene3D G3DSA:3.30.70.260 2 75 5.2E-5 T 12-10-2018 AFR_06830 afb2fccbf980589aadda83e6bc52d735 157 SUPERFAMILY SSF102462 25 156 5.23E-25 T 12-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 AFR_06830 afb2fccbf980589aadda83e6bc52d735 157 Pfam PF09391 Protein of unknown function (DUF2000) 26 156 2.7E-37 T 12-10-2018 IPR018988 Protein of unknown function DUF2000 AFR_06830 afb2fccbf980589aadda83e6bc52d735 157 Gene3D G3DSA:3.40.1490.10 24 156 7.8E-11 T 12-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 AFR_09285 d08d512405a54b43ddaac93070922c7a 618 Pfam PF02277 Phosphoribosyltransferase 271 580 2.1E-57 T 12-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFR_09285 d08d512405a54b43ddaac93070922c7a 618 Gene3D G3DSA:3.40.50.10210 329 572 5.0E-49 T 12-10-2018 AFR_09285 d08d512405a54b43ddaac93070922c7a 618 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 1 166 1.2E-47 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 AFR_09285 d08d512405a54b43ddaac93070922c7a 618 SUPERFAMILY SSF52733 269 578 1.03E-41 T 12-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFR_09285 d08d512405a54b43ddaac93070922c7a 618 Gene3D G3DSA:3.40.50.300 1 169 2.5E-46 T 12-10-2018 AFR_09285 d08d512405a54b43ddaac93070922c7a 618 SUPERFAMILY SSF52540 1 169 2.02E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_19975 9e6fdf52ce4e94f7d36acf52d187dbbe 681 Pfam PF17048 Neutral/alkaline non-lysosomal ceramidase, C-terminal 522 679 1.7E-53 T 12-10-2018 IPR031331 Neutral/alkaline non-lysosomal ceramidase, C-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119 AFR_19975 9e6fdf52ce4e94f7d36acf52d187dbbe 681 Gene3D G3DSA:2.60.40.2300 554 681 5.6E-47 T 12-10-2018 IPR038445 Neutral ceramidase, C-terminal domain superfamily KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119 AFR_19975 9e6fdf52ce4e94f7d36acf52d187dbbe 681 Pfam PF04734 Neutral/alkaline non-lysosomal ceramidase, N-terminal 42 519 9.3E-170 T 12-10-2018 IPR031329 Neutral/alkaline non-lysosomal ceramidase, N-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119|Reactome: R-HSA-1660662 AFR_28575 98c325fd75852f5e6bde2e2e12f3bbad 209 Gene3D G3DSA:1.10.357.10 1 202 3.3E-47 T 12-10-2018 AFR_28575 98c325fd75852f5e6bde2e2e12f3bbad 209 SUPERFAMILY SSF48498 83 199 8.9E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_28575 98c325fd75852f5e6bde2e2e12f3bbad 209 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 87 198 2.5E-12 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal AFR_28575 98c325fd75852f5e6bde2e2e12f3bbad 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 8.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_28575 98c325fd75852f5e6bde2e2e12f3bbad 209 SUPERFAMILY SSF46689 2 81 1.03E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_11150 348c7d6278e8c5a9c69f013d6124ff8d 376 Gene3D G3DSA:3.40.640.10 54 272 1.7E-114 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFR_11150 348c7d6278e8c5a9c69f013d6124ff8d 376 Pfam PF00155 Aminotransferase class I and II 56 367 7.5E-32 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFR_11150 348c7d6278e8c5a9c69f013d6124ff8d 376 SUPERFAMILY SSF53383 17 372 8.25E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFR_11150 348c7d6278e8c5a9c69f013d6124ff8d 376 Gene3D G3DSA:3.90.1150.10 16 369 1.7E-114 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFR_01955 ddd4cf17b3446fc6abe613fd2a31972f 279 Pfam PF04468 PSP1 C-terminal conserved region 60 148 1.9E-17 T 12-10-2018 IPR007557 PSP1, C-terminal AFR_09435 37efce0905eab68b6904398d24001b96 541 Gene3D G3DSA:1.20.810.10 7 444 1.5E-84 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 AFR_09435 37efce0905eab68b6904398d24001b96 541 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 118 291 1.9E-59 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFR_09435 37efce0905eab68b6904398d24001b96 541 SUPERFAMILY SSF81342 20 295 4.4E-61 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFR_25655 c6085518df503c34c435fa385ce3d9bb 805 Pfam PF12704 MacB-like periplasmic core domain 3 202 1.5E-12 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_25655 c6085518df503c34c435fa385ce3d9bb 805 Pfam PF02687 FtsX-like permease family 262 358 1.9E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_25655 c6085518df503c34c435fa385ce3d9bb 805 Pfam PF02687 FtsX-like permease family 711 799 1.7E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_07910 64cd000d3efe0906ea34625f5699af65 317 Gene3D G3DSA:3.40.50.12230 1 308 2.0E-82 T 12-10-2018 AFR_07910 64cd000d3efe0906ea34625f5699af65 317 SUPERFAMILY SSF53328 1 204 4.71E-54 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_07910 64cd000d3efe0906ea34625f5699af65 317 Pfam PF02911 Formyl transferase, C-terminal domain 204 306 2.8E-17 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_07910 64cd000d3efe0906ea34625f5699af65 317 Pfam PF00551 Formyl transferase 1 169 1.3E-28 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFR_07910 64cd000d3efe0906ea34625f5699af65 317 SUPERFAMILY SSF50486 204 308 5.65E-18 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 AFR_39425 9ffe7024970a6db6066d6012dd318dfb 153 Gene3D G3DSA:3.10.490.10 3 153 7.0E-44 T 12-10-2018 AFR_39425 9ffe7024970a6db6066d6012dd318dfb 153 Pfam PF13772 AIG2-like family 60 141 1.2E-19 T 12-10-2018 AFR_39425 9ffe7024970a6db6066d6012dd318dfb 153 SUPERFAMILY SSF110857 3 122 1.31E-18 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily AFR_13985 a46671dda203e4659610b42bf73202b3 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 315 4.6E-36 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_13985 a46671dda203e4659610b42bf73202b3 318 Gene3D G3DSA:1.10.3720.10 85 308 8.4E-16 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13985 a46671dda203e4659610b42bf73202b3 318 SUPERFAMILY SSF161098 93 298 5.23E-11 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13500 f852bb7fb7d86dc757868c6854ad7d10 309 SUPERFAMILY SSF51735 4 300 5.19E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13500 f852bb7fb7d86dc757868c6854ad7d10 309 Gene3D G3DSA:3.40.50.720 2 306 9.3E-60 T 12-10-2018 AFR_13500 f852bb7fb7d86dc757868c6854ad7d10 309 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 6 247 7.7E-30 T 12-10-2018 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 AFR_15225 6c25fbc2f18cd4da02c327ab0d8e1d01 401 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 9 369 2.8E-86 T 12-10-2018 IPR010640 Low temperature requirement A AFR_32445 6ab0b94235d28f53355525da8b2cb195 311 PIRSF PIRSF000707 2 310 1.2E-77 T 12-10-2018 IPR016259 Hygromycin-B kinase AFR_32445 6ab0b94235d28f53355525da8b2cb195 311 SUPERFAMILY SSF56112 60 277 8.89E-30 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_32445 6ab0b94235d28f53355525da8b2cb195 311 Gene3D G3DSA:3.90.1200.10 120 285 1.2E-15 T 12-10-2018 AFR_32445 6ab0b94235d28f53355525da8b2cb195 311 Pfam PF01636 Phosphotransferase enzyme family 60 267 2.9E-27 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_37655 d4518243a932c8284804c685c3c26c96 154 Pfam PF04892 VanZ like family 12 131 4.2E-19 T 12-10-2018 IPR006976 VanZ-like AFR_07800 f6a287cf63357c76c28621e52c8aae62 262 Gene3D G3DSA:2.40.33.20 1 137 2.2E-13 T 12-10-2018 AFR_07800 f6a287cf63357c76c28621e52c8aae62 262 Gene3D G3DSA:2.40.33.20 181 262 3.8E-8 T 12-10-2018 AFR_07800 f6a287cf63357c76c28621e52c8aae62 262 SUPERFAMILY SSF50800 195 252 1.31E-9 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_07800 f6a287cf63357c76c28621e52c8aae62 262 SUPERFAMILY SSF50800 2 106 8.37E-20 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_13210 cfcbd3530a19a3bf14ea709345e8f090 157 SUPERFAMILY SSF46785 4 150 3.4E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_13210 cfcbd3530a19a3bf14ea709345e8f090 157 SMART SM00347 33 136 1.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_13210 cfcbd3530a19a3bf14ea709345e8f090 157 Gene3D G3DSA:1.10.10.10 7 154 1.4E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_26900 c09a8211ba98757be80028248fd02247 281 Pfam PF13649 Methyltransferase domain 52 144 9.6E-18 T 12-10-2018 AFR_26900 c09a8211ba98757be80028248fd02247 281 SUPERFAMILY SSF53335 25 212 5.47E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_26900 c09a8211ba98757be80028248fd02247 281 Gene3D G3DSA:3.40.50.150 35 262 8.7E-39 T 12-10-2018 AFR_22270 3aa5f2ac5aa1668ca7c7f4352e781090 332 Gene3D G3DSA:3.40.190.10 50 311 1.4E-69 T 12-10-2018 AFR_22270 3aa5f2ac5aa1668ca7c7f4352e781090 332 SUPERFAMILY SSF53850 30 252 1.4E-32 T 12-10-2018 AFR_22270 3aa5f2ac5aa1668ca7c7f4352e781090 332 Pfam PF09084 NMT1/THI5 like 68 205 1.0E-10 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_22270 3aa5f2ac5aa1668ca7c7f4352e781090 332 Gene3D G3DSA:3.40.190.10 109 207 1.4E-69 T 12-10-2018 AFR_01725 943e18cc99758bc78e4ba58814773749 338 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFR_01725 943e18cc99758bc78e4ba58814773749 338 Pfam PF00348 Polyprenyl synthetase 45 271 3.7E-58 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFR_01725 943e18cc99758bc78e4ba58814773749 338 Gene3D G3DSA:1.10.600.10 14 338 1.7E-101 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_01725 943e18cc99758bc78e4ba58814773749 338 SUPERFAMILY SSF48576 24 337 9.92E-80 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFR_09325 0c69a96c9654fbaad21658c0447bb4a7 203 SMART SM00530 32 87 6.6E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_09325 0c69a96c9654fbaad21658c0447bb4a7 203 Gene3D G3DSA:1.10.260.40 17 95 1.8E-17 T 12-10-2018 AFR_09325 0c69a96c9654fbaad21658c0447bb4a7 203 SUPERFAMILY SSF51182 80 200 1.78E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_09325 0c69a96c9654fbaad21658c0447bb4a7 203 Pfam PF01381 Helix-turn-helix 33 85 5.5E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_09325 0c69a96c9654fbaad21658c0447bb4a7 203 Pfam PF07883 Cupin domain 131 191 1.9E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFR_09325 0c69a96c9654fbaad21658c0447bb4a7 203 Gene3D G3DSA:2.60.120.10 117 203 4.6E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_09325 0c69a96c9654fbaad21658c0447bb4a7 203 SUPERFAMILY SSF47413 27 93 5.35E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_14630 ab6b9d61a5e26935470c5cb1ec10122a 453 PIRSF PIRSF004810 6 449 2.6E-120 T 12-10-2018 IPR014047 Chromate transporter, long chain AFR_14630 ab6b9d61a5e26935470c5cb1ec10122a 453 TIGRFAM TIGR00937 2A51: chromate efflux transporter 24 423 1.2E-62 T 12-10-2018 IPR014047 Chromate transporter, long chain AFR_14630 ab6b9d61a5e26935470c5cb1ec10122a 453 Pfam PF02417 Chromate transporter 250 442 6.6E-32 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFR_14630 ab6b9d61a5e26935470c5cb1ec10122a 453 Pfam PF02417 Chromate transporter 17 177 5.2E-31 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFR_17510 21e692e01ae19c6ac8c941572ae80bb0 201 Pfam PF03358 NADPH-dependent FMN reductase 17 160 6.7E-18 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_17510 21e692e01ae19c6ac8c941572ae80bb0 201 SUPERFAMILY SSF52218 4 194 4.19E-22 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_17510 21e692e01ae19c6ac8c941572ae80bb0 201 Gene3D G3DSA:3.40.50.360 1 197 1.6E-16 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_17640 e9aa0d4d104149d62b998528f0621089 170 Gene3D G3DSA:3.30.450.40 23 170 7.4E-10 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_17640 e9aa0d4d104149d62b998528f0621089 170 Pfam PF13185 GAF domain 35 156 7.8E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_17640 e9aa0d4d104149d62b998528f0621089 170 SUPERFAMILY SSF55781 31 168 7.46E-13 T 12-10-2018 AFR_38240 4af1b80e90097a639d354e37e32e33a1 417 Pfam PF07394 Protein of unknown function (DUF1501) 51 370 2.3E-28 T 12-10-2018 IPR010869 Protein of unknown function DUF1501 AFR_42985 4ed8d69c4c7efbb5c48a00f673c769a3 346 Pfam PF02096 60Kd inner membrane protein 38 256 5.3E-53 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFR_42985 4ed8d69c4c7efbb5c48a00f673c769a3 346 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 37 256 8.7E-56 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFR_28660 5615a7508bf07cbe5eddbd3cf17b0af2 304 Gene3D G3DSA:3.10.180.10 146 302 1.4E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_28660 5615a7508bf07cbe5eddbd3cf17b0af2 304 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 146 263 6.2E-14 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_28660 5615a7508bf07cbe5eddbd3cf17b0af2 304 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 3 304 1.1E-104 T 12-10-2018 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 AFR_28660 5615a7508bf07cbe5eddbd3cf17b0af2 304 SUPERFAMILY SSF54593 1 271 7.87E-38 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_28660 5615a7508bf07cbe5eddbd3cf17b0af2 304 Gene3D G3DSA:3.10.180.10 1 130 9.0E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_03545 be825fc6129d957751b5ca792e39d90b 153 Gene3D G3DSA:3.30.530.20 2 151 2.0E-29 T 12-10-2018 IPR023393 START-like domain superfamily AFR_03545 be825fc6129d957751b5ca792e39d90b 153 SUPERFAMILY SSF55961 4 148 1.51E-27 T 12-10-2018 AFR_03545 be825fc6129d957751b5ca792e39d90b 153 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 12 144 6.5E-21 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 SMART SM00560 1049 1203 1.4E-8 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 SMART SM00560 790 939 1.4E-5 T 12-10-2018 IPR006558 LamG-like jellyroll fold AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 SUPERFAMILY SSF49899 984 1211 9.29E-19 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 Gene3D G3DSA:2.60.120.200 1038 1219 2.0E-22 T 12-10-2018 AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 Gene3D G3DSA:2.60.120.200 762 971 3.5E-24 T 12-10-2018 AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1045 1206 5.5E-17 T 12-10-2018 AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 783 940 2.1E-22 T 12-10-2018 AFR_39170 d6a3461d48289f7ed92dfe71aa889fdc 1222 SUPERFAMILY SSF49899 753 940 1.24E-20 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_12330 ef83be0e1313e3d87ead461bbdf6c017 227 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 10 207 2.3E-26 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 AFR_01635 ae211aa8efbb6e6e4db4e4711b751686 255 Pfam PF14062 Domain of unknown function (DUF4253) 141 255 5.9E-30 T 12-10-2018 IPR025349 Domain of unknown function DUF4253 AFR_28015 00ac0c5a1b282247d989f2faa385e796 297 SUPERFAMILY SSF52980 160 272 1.72E-17 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_28015 00ac0c5a1b282247d989f2faa385e796 297 Pfam PF14338 Mrr N-terminal domain 6 89 5.7E-24 T 12-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain AFR_28015 00ac0c5a1b282247d989f2faa385e796 297 Pfam PF04471 Restriction endonuclease 156 271 6.8E-36 T 12-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFR_28015 00ac0c5a1b282247d989f2faa385e796 297 Gene3D G3DSA:3.40.91.100 130 294 5.8E-9 T 12-10-2018 AFR_26425 0848ad1f6b952a0cb6f1bec7f25a0cc1 97 SUPERFAMILY SSF54862 11 83 9.91E-11 T 12-10-2018 AFR_26425 0848ad1f6b952a0cb6f1bec7f25a0cc1 97 Gene3D G3DSA:3.30.70.20 7 84 2.4E-20 T 12-10-2018 AFR_26425 0848ad1f6b952a0cb6f1bec7f25a0cc1 97 PRINTS PR00352 3Fe-4S ferredoxin signature 14 25 1.5E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_26425 0848ad1f6b952a0cb6f1bec7f25a0cc1 97 PRINTS PR00352 3Fe-4S ferredoxin signature 68 80 1.5E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_26425 0848ad1f6b952a0cb6f1bec7f25a0cc1 97 PRINTS PR00352 3Fe-4S ferredoxin signature 25 35 1.5E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFR_26425 0848ad1f6b952a0cb6f1bec7f25a0cc1 97 Pfam PF13459 4Fe-4S single cluster domain 12 82 6.1E-20 T 12-10-2018 AFR_08925 8b3f711cce8bc041a5c27fd179244460 250 Pfam PF01925 Sulfite exporter TauE/SafE 10 243 8.5E-38 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFR_24225 6937a3291d2c3a7a88d20e3532a6cae6 296 Gene3D G3DSA:3.40.50.720 2 293 2.8E-35 T 12-10-2018 AFR_24225 6937a3291d2c3a7a88d20e3532a6cae6 296 SUPERFAMILY SSF51735 1 286 4.55E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24225 6937a3291d2c3a7a88d20e3532a6cae6 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 75 1.1E-9 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_38720 c84f6fea38e7937d25d9bec77b3399d5 215 Gene3D G3DSA:3.30.110.170 9 204 3.8E-26 T 12-10-2018 AFR_38720 c84f6fea38e7937d25d9bec77b3399d5 215 Pfam PF04402 Protein of unknown function (DUF541) 7 205 6.8E-30 T 12-10-2018 IPR007497 Protein of unknown function DUF541 AFR_38720 c84f6fea38e7937d25d9bec77b3399d5 215 Gene3D G3DSA:3.30.70.2970 19 124 3.8E-26 T 12-10-2018 AFR_29470 e7d6db709162daf8240b211706912a01 193 SUPERFAMILY SSF46689 2 58 1.54E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_29470 e7d6db709162daf8240b211706912a01 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 41 9.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_29470 e7d6db709162daf8240b211706912a01 193 Gene3D G3DSA:1.10.357.10 1 183 3.5E-23 T 12-10-2018 AFR_33160 cab7fdc0c2a6730bee276880e5024e7b 364 SUPERFAMILY SSF55874 254 359 3.51E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33160 cab7fdc0c2a6730bee276880e5024e7b 364 Pfam PF07730 Histidine kinase 168 233 1.1E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_33160 cab7fdc0c2a6730bee276880e5024e7b 364 Gene3D G3DSA:3.30.565.10 239 360 5.3E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25675 62bb40fd210224f6c5192e2d115f1a4b 174 Pfam PF01584 CheW-like domain 30 153 3.5E-14 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFR_25675 62bb40fd210224f6c5192e2d115f1a4b 174 SUPERFAMILY SSF50341 24 154 2.22E-18 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFR_25675 62bb40fd210224f6c5192e2d115f1a4b 174 Gene3D G3DSA:2.40.50.180 50 136 3.4E-8 T 12-10-2018 AFR_06020 565ce4de38c43c76c4c5c76655382c45 105 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 103 6.0E-21 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_06020 565ce4de38c43c76c4c5c76655382c45 105 Gene3D G3DSA:3.30.750.24 7 105 2.5E-25 T 12-10-2018 IPR036513 STAS domain superfamily AFR_06020 565ce4de38c43c76c4c5c76655382c45 105 Pfam PF13466 STAS domain 18 97 2.2E-15 T 12-10-2018 IPR002645 STAS domain AFR_06020 565ce4de38c43c76c4c5c76655382c45 105 SUPERFAMILY SSF52091 10 103 6.28E-23 T 12-10-2018 IPR036513 STAS domain superfamily AFR_34210 f9a2b6d9f3cd9be0a0bf8ade02ff305d 381 SUPERFAMILY SSF55874 279 376 4.6E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_34210 f9a2b6d9f3cd9be0a0bf8ade02ff305d 381 Pfam PF07730 Histidine kinase 184 248 7.9E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_34210 f9a2b6d9f3cd9be0a0bf8ade02ff305d 381 Gene3D G3DSA:3.30.565.10 258 377 2.3E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_27510 1924f889e28f2e7c2076a8d1dcd21dd2 389 Pfam PF01590 GAF domain 97 187 2.1E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFR_27510 1924f889e28f2e7c2076a8d1dcd21dd2 389 Gene3D G3DSA:3.30.450.40 32 210 7.6E-46 T 12-10-2018 IPR029016 GAF-like domain superfamily AFR_40705 8a58bcfc15a353ae871c5ce1e1b4e020 120 SUPERFAMILY SSF75169 6 112 5.38E-17 T 12-10-2018 IPR027396 DsrEFH-like AFR_40705 8a58bcfc15a353ae871c5ce1e1b4e020 120 Pfam PF02635 DsrE/DsrF-like family 10 109 3.8E-10 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFR_40705 8a58bcfc15a353ae871c5ce1e1b4e020 120 Gene3D G3DSA:3.40.1260.10 2 116 3.3E-23 T 12-10-2018 IPR027396 DsrEFH-like AFR_16480 0e467ff0532f266539f900a8574531ec 493 Gene3D G3DSA:1.20.1720.10 23 227 2.9E-41 T 12-10-2018 AFR_16480 0e467ff0532f266539f900a8574531ec 493 Pfam PF00083 Sugar (and other) transporter 315 471 2.2E-6 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFR_16480 0e467ff0532f266539f900a8574531ec 493 Gene3D G3DSA:1.20.1250.20 268 479 3.3E-20 T 12-10-2018 AFR_16480 0e467ff0532f266539f900a8574531ec 493 Pfam PF07690 Major Facilitator Superfamily 29 302 4.3E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_16480 0e467ff0532f266539f900a8574531ec 493 SUPERFAMILY SSF103473 25 472 1.83E-64 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_26825 4be4859c35753c42126d5eba29fbe6d8 321 SMART SM01236 155 260 2.0E-38 T 12-10-2018 AFR_26825 4be4859c35753c42126d5eba29fbe6d8 321 Pfam PF14518 Iron-containing redox enzyme 124 298 3.4E-47 T 12-10-2018 AFR_26825 4be4859c35753c42126d5eba29fbe6d8 321 SUPERFAMILY SSF48613 109 299 1.56E-14 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_26825 4be4859c35753c42126d5eba29fbe6d8 321 Gene3D G3DSA:1.20.910.10 105 312 1.3E-31 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFR_20380 396864dbe54b3f94b1c5f37c9de5dd27 375 Gene3D G3DSA:3.30.565.10 271 374 5.3E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20380 396864dbe54b3f94b1c5f37c9de5dd27 375 SUPERFAMILY SSF55874 293 359 9.23E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20380 396864dbe54b3f94b1c5f37c9de5dd27 375 Pfam PF07730 Histidine kinase 192 257 2.1E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_01185 99cc198eeaa89e05b36660c78e64ae9d 212 Pfam PF07336 Putative stress-induced transcription regulator 20 135 5.0E-6 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator AFR_01185 99cc198eeaa89e05b36660c78e64ae9d 212 SUPERFAMILY SSF160904 15 190 2.48E-25 T 12-10-2018 AFR_01185 99cc198eeaa89e05b36660c78e64ae9d 212 Gene3D G3DSA:1.10.3300.10 12 192 1.5E-14 T 12-10-2018 IPR023286 ABATE domain superfamily AFR_01185 99cc198eeaa89e05b36660c78e64ae9d 212 Pfam PF11706 CGNR zinc finger 148 191 1.0E-14 T 12-10-2018 IPR021005 Zinc finger, CGNR AFR_41885 f6b4d3ce0337fcddbcf75985c2f34558 149 Pfam PF14437 MafB19-like deaminase 6 147 3.8E-28 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFR_41885 f6b4d3ce0337fcddbcf75985c2f34558 149 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 91 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFR_41885 f6b4d3ce0337fcddbcf75985c2f34558 149 SUPERFAMILY SSF53927 4 147 7.86E-50 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFR_41885 f6b4d3ce0337fcddbcf75985c2f34558 149 Gene3D G3DSA:3.40.140.10 2 149 8.6E-51 T 12-10-2018 AFR_41885 f6b4d3ce0337fcddbcf75985c2f34558 149 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 147 44.478 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFR_11515 83de20199fc912b9552c311ffcc6f469 148 Pfam PF01638 HxlR-like helix-turn-helix 63 133 8.0E-20 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_11515 83de20199fc912b9552c311ffcc6f469 148 Gene3D G3DSA:1.10.10.10 3 146 6.2E-43 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_11515 83de20199fc912b9552c311ffcc6f469 148 SUPERFAMILY SSF46785 17 137 5.4E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01780 9605b4f1a5a5f7f699df96920ea8d6ac 330 Pfam PF07179 SseB protein N-terminal domain 32 125 6.6E-9 T 12-10-2018 IPR009839 SseB protein N-terminal domain AFR_08980 54a4b421370323ad3e6dfd5a0fc4214f 406 Gene3D G3DSA:1.20.1250.20 14 401 1.5E-31 T 12-10-2018 AFR_08980 54a4b421370323ad3e6dfd5a0fc4214f 406 Pfam PF07690 Major Facilitator Superfamily 26 281 2.5E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_08980 54a4b421370323ad3e6dfd5a0fc4214f 406 SUPERFAMILY SSF103473 10 398 1.96E-34 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_40495 1bb6a98a180e18e860f06d8285a5cdde 155 Pfam PF03748 Flagellar basal body-associated protein FliL 61 155 6.3E-14 T 12-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 AFR_38680 a5ed16a72b6a1009dd200a11ba3f5ad6 223 Gene3D G3DSA:3.90.550.10 8 129 4.2E-6 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_38680 a5ed16a72b6a1009dd200a11ba3f5ad6 223 SUPERFAMILY SSF53448 44 128 1.69E-6 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_25440 795b6152f91e36bcfffccf1175570772 110 Gene3D G3DSA:3.30.750.24 1 110 1.2E-31 T 12-10-2018 IPR036513 STAS domain superfamily AFR_25440 795b6152f91e36bcfffccf1175570772 110 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 10 105 8.1E-20 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_25440 795b6152f91e36bcfffccf1175570772 110 Pfam PF13466 STAS domain 15 94 4.3E-18 T 12-10-2018 IPR002645 STAS domain AFR_25440 795b6152f91e36bcfffccf1175570772 110 SUPERFAMILY SSF52091 7 109 1.02E-24 T 12-10-2018 IPR036513 STAS domain superfamily AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 SUPERFAMILY SSF51735 17 260 1.3E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 Pfam PF00106 short chain dehydrogenase 18 201 3.9E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 Gene3D G3DSA:3.40.50.720 14 292 3.6E-74 T 12-10-2018 AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 5.2E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.2E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 5.2E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 5.2E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.2E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12895 4f83c64d28f3189bd58e0e4cc941a5c3 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_22365 645c76c4b1ecde7696757f3fbeb914e1 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 279 5.3E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_22365 645c76c4b1ecde7696757f3fbeb914e1 284 Gene3D G3DSA:1.10.3720.10 74 280 1.5E-17 T 12-10-2018 IPR035906 MetI-like superfamily AFR_22365 645c76c4b1ecde7696757f3fbeb914e1 284 SUPERFAMILY SSF161098 78 265 2.78E-23 T 12-10-2018 IPR035906 MetI-like superfamily AFR_12790 f64f97fa3301ed35e9e49eeb5271e225 265 Pfam PF00005 ABC transporter 45 178 6.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_12790 f64f97fa3301ed35e9e49eeb5271e225 265 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_12790 f64f97fa3301ed35e9e49eeb5271e225 265 SMART SM00382 42 226 3.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_12790 f64f97fa3301ed35e9e49eeb5271e225 265 SUPERFAMILY SSF52540 24 231 1.67E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_12790 f64f97fa3301ed35e9e49eeb5271e225 265 Gene3D G3DSA:3.40.50.300 12 243 6.8E-57 T 12-10-2018 AFR_04225 1e9af41e71255eba65dc40214ea3ea59 165 Pfam PF04542 Sigma-70 region 2 6 72 1.6E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_04225 1e9af41e71255eba65dc40214ea3ea59 165 Gene3D G3DSA:1.10.1740.10 1 74 9.7E-12 T 12-10-2018 AFR_04225 1e9af41e71255eba65dc40214ea3ea59 165 Pfam PF08281 Sigma-70, region 4 96 148 5.6E-18 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_04225 1e9af41e71255eba65dc40214ea3ea59 165 Gene3D G3DSA:1.10.10.10 92 159 1.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04225 1e9af41e71255eba65dc40214ea3ea59 165 SUPERFAMILY SSF88946 2 69 2.9E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_04225 1e9af41e71255eba65dc40214ea3ea59 165 SUPERFAMILY SSF88659 94 152 1.5E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_04225 1e9af41e71255eba65dc40214ea3ea59 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 151 2.9E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_36260 775292dbab011de60378f3c07469ba4d 260 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 36 84 4.1E-14 T 12-10-2018 IPR027805 Transposase, Helix-turn-helix domain AFR_36260 775292dbab011de60378f3c07469ba4d 260 Pfam PF13359 DDE superfamily endonuclease 102 251 1.7E-30 T 12-10-2018 IPR027806 Harbinger transposase-derived nuclease domain AFR_36300 5867cfced2ae295b7f4c2786393dcf0d 216 Pfam PF00717 Peptidase S24-like 41 116 3.3E-15 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFR_36300 5867cfced2ae295b7f4c2786393dcf0d 216 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 92 104 4.3E-17 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_36300 5867cfced2ae295b7f4c2786393dcf0d 216 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 145 164 4.3E-17 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_36300 5867cfced2ae295b7f4c2786393dcf0d 216 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 35 51 4.3E-17 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_36300 5867cfced2ae295b7f4c2786393dcf0d 216 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 22 194 2.0E-39 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFR_36300 5867cfced2ae295b7f4c2786393dcf0d 216 SUPERFAMILY SSF51306 33 200 6.8E-40 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFR_36300 5867cfced2ae295b7f4c2786393dcf0d 216 ProSitePatterns PS00761 Signal peptidases I signature 3. 150 163 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 AFR_39490 ad3b857baeed5c1f8d65c70fabaa2aea 160 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_39490 ad3b857baeed5c1f8d65c70fabaa2aea 160 Pfam PF00293 NUDIX domain 11 134 1.3E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_39490 ad3b857baeed5c1f8d65c70fabaa2aea 160 SUPERFAMILY SSF55811 6 153 6.77E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_39490 ad3b857baeed5c1f8d65c70fabaa2aea 160 Gene3D G3DSA:3.90.79.10 7 154 3.4E-29 T 12-10-2018 AFR_27900 281cdc9d171bc78003cdb489ba458ea7 223 SUPERFAMILY SSF160104 3 204 1.1E-22 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFR_27900 281cdc9d171bc78003cdb489ba458ea7 223 Gene3D G3DSA:2.40.400.10 1 177 6.1E-18 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFR_27900 281cdc9d171bc78003cdb489ba458ea7 223 Pfam PF06314 Acetoacetate decarboxylase (ADC) 28 163 2.5E-10 T 12-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFR_42860 ef5454cd1e5ecbd6a9f757c72b124820 896 Pfam PF00912 Transglycosylase 153 340 3.6E-50 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_42860 ef5454cd1e5ecbd6a9f757c72b124820 896 SUPERFAMILY SSF53955 141 345 5.06E-52 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_42860 ef5454cd1e5ecbd6a9f757c72b124820 896 Pfam PF00905 Penicillin binding protein transpeptidase domain 449 730 3.8E-30 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFR_42860 ef5454cd1e5ecbd6a9f757c72b124820 896 Gene3D G3DSA:1.10.3810.10 146 350 7.1E-55 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_42860 ef5454cd1e5ecbd6a9f757c72b124820 896 Gene3D G3DSA:3.40.710.10 383 802 8.1E-84 T 12-10-2018 AFR_42860 ef5454cd1e5ecbd6a9f757c72b124820 896 SUPERFAMILY SSF56601 322 793 9.82E-63 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_09840 a624bf97cef67bed718a893eac0025f2 193 Pfam PF00583 Acetyltransferase (GNAT) family 55 153 5.1E-6 T 12-10-2018 IPR000182 GNAT domain AFR_09840 a624bf97cef67bed718a893eac0025f2 193 SUPERFAMILY SSF55729 3 160 1.4E-13 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_09840 a624bf97cef67bed718a893eac0025f2 193 Gene3D G3DSA:3.40.630.30 2 173 7.4E-13 T 12-10-2018 AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 4.6E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 Gene3D G3DSA:1.10.10.60 5 57 5.5E-16 T 12-10-2018 AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 188 9.2E-22 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 Gene3D G3DSA:1.10.357.10 58 197 7.6E-20 T 12-10-2018 AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 SUPERFAMILY SSF48498 78 194 7.78E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_13225 7cacd5fd68524137fc6740c4781ffb80 210 SUPERFAMILY SSF46689 7 71 1.85E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_30095 10ff8ee687ddaea2c74bb0be533d198d 432 SUPERFAMILY SSF53850 34 422 6.92E-55 T 12-10-2018 AFR_30095 10ff8ee687ddaea2c74bb0be533d198d 432 Gene3D G3DSA:3.40.190.10 22 425 2.5E-60 T 12-10-2018 AFR_30095 10ff8ee687ddaea2c74bb0be533d198d 432 Pfam PF13416 Bacterial extracellular solute-binding protein 51 323 4.4E-25 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFR_02010 4362b7ce377898b7a6f5afc646939cba 66 Pfam PF04149 Domain of unknown function (DUF397) 8 59 5.0E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_34650 5b65d2e26424a9f531fb21f7e2b8fcf0 367 Pfam PF00953 Glycosyl transferase family 4 91 284 4.7E-34 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 AFR_34650 5b65d2e26424a9f531fb21f7e2b8fcf0 367 ProSitePatterns PS01348 MraY family signature 2. 184 195 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_34650 5b65d2e26424a9f531fb21f7e2b8fcf0 367 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 359 21.33 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_34650 5b65d2e26424a9f531fb21f7e2b8fcf0 367 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 351 3.8E-82 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_26285 257dc1c90c41e91e645441a03f4e33a4 434 Pfam PF00544 Pectate lyase 139 348 2.3E-46 T 12-10-2018 IPR002022 Pectate lyase AFR_26285 257dc1c90c41e91e645441a03f4e33a4 434 SUPERFAMILY SSF51126 45 431 1.46E-65 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_26285 257dc1c90c41e91e645441a03f4e33a4 434 Gene3D G3DSA:2.160.20.10 34 433 4.2E-139 T 12-10-2018 IPR012334 Pectin lyase fold AFR_26285 257dc1c90c41e91e645441a03f4e33a4 434 SMART SM00656 104 354 1.8E-44 T 12-10-2018 IPR002022 Pectate lyase AFR_17555 6e93f3a1afecb1d3f5b4bdd0f6d2d2cb 357 Gene3D G3DSA:2.130.10.130 59 229 9.2E-8 T 12-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 AFR_17555 6e93f3a1afecb1d3f5b4bdd0f6d2d2cb 357 SUPERFAMILY SSF69318 27 319 1.19E-29 T 12-10-2018 AFR_17555 6e93f3a1afecb1d3f5b4bdd0f6d2d2cb 357 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 43 105 2.2E-7 T 12-10-2018 AFR_17555 6e93f3a1afecb1d3f5b4bdd0f6d2d2cb 357 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 147 209 3.3E-7 T 12-10-2018 AFR_26150 e43e09152c7765ff453fcc85255588b3 251 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 16 239 3.2E-40 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 AFR_26150 e43e09152c7765ff453fcc85255588b3 251 Gene3D G3DSA:3.20.20.60 1 249 1.0E-76 T 12-10-2018 AFR_26150 e43e09152c7765ff453fcc85255588b3 251 SUPERFAMILY SSF51621 4 247 3.05E-67 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_00320 21ba6ee85d4984e023310d23f05d4f02 87 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 87 17.287 T 12-10-2018 IPR009619 Cell division protein CrgA AFR_00320 21ba6ee85d4984e023310d23f05d4f02 87 Pfam PF06781 Cell division protein CrgA 2 87 4.8E-28 T 12-10-2018 IPR009619 Cell division protein CrgA AFR_19070 1451512fd0b22f858f0202725693c091 186 SUPERFAMILY SSF49899 56 167 2.88E-5 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFR_34280 27a3fef763e387f627dcb591aabc1a70 429 Gene3D G3DSA:3.40.710.10 6 305 3.3E-77 T 12-10-2018 AFR_34280 27a3fef763e387f627dcb591aabc1a70 429 Pfam PF00144 Beta-lactamase 23 286 5.0E-37 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_34280 27a3fef763e387f627dcb591aabc1a70 429 SUPERFAMILY SSF56601 12 302 6.97E-77 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_16810 88f50ff2930f1d1c3a418fc6709fca57 229 Pfam PF05103 DivIVA protein 3 55 6.5E-11 T 12-10-2018 IPR007793 DivIVA family AFR_16810 88f50ff2930f1d1c3a418fc6709fca57 229 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 1.6E-14 T 12-10-2018 IPR019933 DivIVA domain AFR_08545 7957a8b3845ee335ac557f23d9604355 194 Pfam PF13559 Domain of unknown function (DUF4129) 113 180 3.0E-12 T 12-10-2018 IPR025403 Domain of unknown function DUF4129 AFR_37265 9f9e982f89c2c92591b7eeb59dc54c0d 208 Pfam PF13548 Domain of unknown function (DUF4126) 5 187 1.2E-56 T 12-10-2018 IPR025196 Domain of unknown function DUF4126 AFR_26730 7b74909584a740daea7e79f16e3b5fd1 246 SUPERFAMILY SSF117396 3 233 1.83E-69 T 12-10-2018 IPR036520 UPF0759 superfamily AFR_26730 7b74909584a740daea7e79f16e3b5fd1 246 Gene3D G3DSA:3.20.20.410 1 238 3.3E-65 T 12-10-2018 IPR036520 UPF0759 superfamily AFR_26730 7b74909584a740daea7e79f16e3b5fd1 246 Pfam PF01904 Protein of unknown function DUF72 21 233 2.7E-55 T 12-10-2018 IPR002763 Protein of unknown function DUF72 AFR_23615 f547c4f8536b67a62d4ecc702a5e5aea 351 SUPERFAMILY SSF53807 42 316 3.92E-48 T 12-10-2018 AFR_23615 f547c4f8536b67a62d4ecc702a5e5aea 351 Pfam PF01497 Periplasmic binding protein 87 301 8.0E-23 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFR_23615 f547c4f8536b67a62d4ecc702a5e5aea 351 Gene3D G3DSA:3.40.50.1980 37 181 9.8E-41 T 12-10-2018 AFR_23615 f547c4f8536b67a62d4ecc702a5e5aea 351 Gene3D G3DSA:3.40.50.1980 184 340 6.4E-42 T 12-10-2018 AFR_20910 7aec80f3b5568b8b82265203a138d947 316 SUPERFAMILY SSF55874 208 311 3.61E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_20910 7aec80f3b5568b8b82265203a138d947 316 Pfam PF07730 Histidine kinase 84 118 1.3E-7 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_20910 7aec80f3b5568b8b82265203a138d947 316 Gene3D G3DSA:3.30.565.10 195 312 8.7E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_32285 4a6fb26e8d67bbbef9f6776ad1851dc4 354 Pfam PF01032 FecCD transport family 38 348 1.8E-89 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_32285 4a6fb26e8d67bbbef9f6776ad1851dc4 354 SUPERFAMILY SSF81345 29 349 2.62E-78 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_32285 4a6fb26e8d67bbbef9f6776ad1851dc4 354 Gene3D G3DSA:1.10.3470.10 26 352 8.8E-95 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_06435 0d7a147e21447ab7cd9429b988daf1f9 267 SUPERFAMILY SSF50800 2 240 3.24E-17 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_06435 0d7a147e21447ab7cd9429b988daf1f9 267 Pfam PF03476 MOSC N-terminal beta barrel domain 2 60 7.2E-14 T 12-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 AFR_06435 0d7a147e21447ab7cd9429b988daf1f9 267 Pfam PF03473 MOSC domain 134 261 3.7E-27 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 AFR_06435 0d7a147e21447ab7cd9429b988daf1f9 267 SUPERFAMILY SSF141673 3 124 1.2E-18 T 12-10-2018 AFR_26785 937a16eb95ebef5d8838f0b4b1c459b5 245 SUPERFAMILY SSF52091 15 115 6.67E-8 T 12-10-2018 IPR036513 STAS domain superfamily AFR_26785 937a16eb95ebef5d8838f0b4b1c459b5 245 SUPERFAMILY SSF55874 155 232 4.14E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_26785 937a16eb95ebef5d8838f0b4b1c459b5 245 Pfam PF13581 Histidine kinase-like ATPase domain 132 237 7.3E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_26785 937a16eb95ebef5d8838f0b4b1c459b5 245 Gene3D G3DSA:3.30.750.24 10 118 2.0E-8 T 12-10-2018 IPR036513 STAS domain superfamily AFR_26785 937a16eb95ebef5d8838f0b4b1c459b5 245 Gene3D G3DSA:3.30.565.10 120 244 5.0E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_15860 2597b50a589e997b829c491e0f0ef2b0 163 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 3 157 2.7E-21 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 AFR_42345 611f671fb3ec0a6851e3a15ab7867731 294 SUPERFAMILY SSF53098 103 288 5.18E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_42345 611f671fb3ec0a6851e3a15ab7867731 294 Pfam PF00665 Integrase core domain 103 245 2.8E-30 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFR_42345 611f671fb3ec0a6851e3a15ab7867731 294 Gene3D G3DSA:3.30.420.10 137 287 5.0E-19 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFR_42345 611f671fb3ec0a6851e3a15ab7867731 294 Pfam PF13011 leucine-zipper of insertion element IS481 2 55 1.2E-13 T 12-10-2018 IPR024967 DNA-binding domain, IS481-type AFR_42345 611f671fb3ec0a6851e3a15ab7867731 294 SUPERFAMILY SSF46689 2 82 8.96E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_39575 2e3904cbb17f11927e2318666f995724 425 Pfam PF02653 Branched-chain amino acid transport system / permease component 129 404 3.9E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_33605 2b3ce35cdf24779c2e49e63d10317363 291 SUPERFAMILY SSF49482 23 276 1.57E-40 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_33605 2b3ce35cdf24779c2e49e63d10317363 291 Gene3D G3DSA:2.60.130.10 15 265 9.5E-34 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFR_33605 2b3ce35cdf24779c2e49e63d10317363 291 Pfam PF00775 Dioxygenase 109 183 1.6E-9 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 AFR_36725 e3dbd190d45d2dac1f5bd005d8aa19a2 82 Pfam PF01381 Helix-turn-helix 10 62 1.7E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_36725 e3dbd190d45d2dac1f5bd005d8aa19a2 82 Gene3D G3DSA:1.10.260.40 5 69 4.1E-21 T 12-10-2018 AFR_36725 e3dbd190d45d2dac1f5bd005d8aa19a2 82 SUPERFAMILY SSF47413 5 68 6.44E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_36725 e3dbd190d45d2dac1f5bd005d8aa19a2 82 SMART SM00530 9 64 6.7E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_29815 3311a26a5fe36f4062b5c1680484c837 117 Pfam PF03992 Antibiotic biosynthesis monooxygenase 14 72 1.9E-7 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_29815 3311a26a5fe36f4062b5c1680484c837 117 SUPERFAMILY SSF54909 3 81 1.57E-8 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_29815 3311a26a5fe36f4062b5c1680484c837 117 Gene3D G3DSA:3.30.70.100 1 93 1.1E-5 T 12-10-2018 AFR_37400 29c71499b8f860c1b57bbb8db6d861a3 215 Gene3D G3DSA:3.90.870.10 2 212 2.6E-59 T 12-10-2018 AFR_37400 29c71499b8f860c1b57bbb8db6d861a3 215 Pfam PF01300 Telomere recombination 22 196 4.3E-39 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFR_37400 29c71499b8f860c1b57bbb8db6d861a3 215 SUPERFAMILY SSF55821 3 209 4.58E-50 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFR_37400 29c71499b8f860c1b57bbb8db6d861a3 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 205 1.4E-51 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFR_21675 1b5550eca77454f6d94616e384d09e64 314 Gene3D G3DSA:1.10.3720.10 73 312 1.6E-78 T 12-10-2018 IPR035906 MetI-like superfamily AFR_21675 1b5550eca77454f6d94616e384d09e64 314 SUPERFAMILY SSF161098 77 303 3.01E-68 T 12-10-2018 IPR035906 MetI-like superfamily AFR_21675 1b5550eca77454f6d94616e384d09e64 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 301 1.4E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_28875 899acc28d3e3f4420a542ace2cbba725 239 Pfam PF01061 ABC-2 type transporter 7 166 6.6E-8 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_04715 716a4610584204db5b095c109716ffcf 252 Pfam PF08543 Phosphomethylpyrimidine kinase 13 249 1.1E-76 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFR_04715 716a4610584204db5b095c109716ffcf 252 SUPERFAMILY SSF53613 1 251 1.71E-69 T 12-10-2018 IPR029056 Ribokinase-like AFR_04715 716a4610584204db5b095c109716ffcf 252 Gene3D G3DSA:3.40.1190.20 1 252 2.4E-88 T 12-10-2018 IPR029056 Ribokinase-like AFR_04715 716a4610584204db5b095c109716ffcf 252 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 251 5.0E-81 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFR_42130 15cb7deee01faf61e4af63d8b5f2e9ec 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 28 93 1.7E-18 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 AFR_42130 15cb7deee01faf61e4af63d8b5f2e9ec 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 203 272 8.6E-19 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 AFR_42130 15cb7deee01faf61e4af63d8b5f2e9ec 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 112 177 2.2E-10 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 AFR_27470 199880c5ea18f9074189fb41bbab210e 205 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 184 6.5E-27 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_27470 199880c5ea18f9074189fb41bbab210e 205 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 47 3.2E-8 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_27470 199880c5ea18f9074189fb41bbab210e 205 SUPERFAMILY SSF109854 2 121 1.65E-13 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_27470 199880c5ea18f9074189fb41bbab210e 205 Gene3D G3DSA:1.20.120.450 1 59 3.7E-9 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_08040 b6c52494adc8a55b9b48c3dc861b43db 267 Pfam PF02361 Cobalt transport protein 16 222 2.2E-25 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AFR_33635 45c9d1eacebd771cd886c8880617c4d2 366 Pfam PF01757 Acyltransferase family 11 330 2.8E-25 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_25080 4db2bccdd32443504be98dff405fe1e2 155 Pfam PF05305 Protein of unknown function (DUF732) 48 149 1.7E-11 T 12-10-2018 IPR007969 Domain of unknown function DUF732 AFR_36440 868966c06a4b37656aa72b8769e2bc6d 563 SUPERFAMILY SSF56300 125 366 1.06E-7 T 12-10-2018 AFR_36440 868966c06a4b37656aa72b8769e2bc6d 563 Gene3D G3DSA:3.60.21.70 128 479 1.2E-13 T 12-10-2018 IPR038607 PhoD-like superfamily AFR_36440 868966c06a4b37656aa72b8769e2bc6d 563 Pfam PF09423 PhoD-like phosphatase 137 257 2.5E-15 T 12-10-2018 IPR018946 Alkaline phosphatase D-related AFR_09830 1b8705a6abffc2193556ab415dd12733 364 Pfam PF00535 Glycosyl transferase family 2 38 153 7.8E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_09830 1b8705a6abffc2193556ab415dd12733 364 Gene3D G3DSA:3.90.550.10 21 241 8.7E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_09830 1b8705a6abffc2193556ab415dd12733 364 SUPERFAMILY SSF53448 36 240 2.05E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_15435 143d518d265b6711dc6cdfdfad9540d3 97 SUPERFAMILY SSF54909 22 90 1.12E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_15435 143d518d265b6711dc6cdfdfad9540d3 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 12 74 2.8E-8 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFR_15435 143d518d265b6711dc6cdfdfad9540d3 97 Gene3D G3DSA:3.30.70.100 1 94 1.6E-14 T 12-10-2018 AFR_24165 963d983958f3d93ca7de560d533aacc6 362 Pfam PF13407 Periplasmic binding protein domain 41 302 5.2E-47 T 12-10-2018 IPR025997 Periplasmic binding protein AFR_24165 963d983958f3d93ca7de560d533aacc6 362 Gene3D G3DSA:3.40.50.2300 141 342 8.5E-88 T 12-10-2018 AFR_24165 963d983958f3d93ca7de560d533aacc6 362 Gene3D G3DSA:3.40.50.2300 38 324 8.5E-88 T 12-10-2018 AFR_24165 963d983958f3d93ca7de560d533aacc6 362 SUPERFAMILY SSF53822 37 337 2.72E-48 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFR_26540 524de5b3dd2c0d3f75481d074ef1a5ef 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 23 108 5.1E-11 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_26540 524de5b3dd2c0d3f75481d074ef1a5ef 170 SUPERFAMILY SSF50475 16 154 1.96E-21 T 12-10-2018 AFR_26540 524de5b3dd2c0d3f75481d074ef1a5ef 170 Gene3D G3DSA:2.30.110.10 20 154 4.3E-17 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_16975 5f7d23aef7b3d2efef9238e86c864b89 233 Gene3D G3DSA:3.40.50.880 3 233 8.0E-38 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_16975 5f7d23aef7b3d2efef9238e86c864b89 233 SUPERFAMILY SSF52317 5 233 3.2E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_16975 5f7d23aef7b3d2efef9238e86c864b89 233 Pfam PF06283 Trehalose utilisation 6 231 5.5E-41 T 12-10-2018 IPR029010 ThuA-like domain AFR_40155 615f57c0dcb1893ff1b08d548c5afcd4 180 SUPERFAMILY SSF53955 5 176 1.91E-29 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFR_11760 6112bd5f75b8c06a5006d245457a90f2 185 Gene3D G3DSA:3.40.430.10 3 181 1.5E-31 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_11760 6112bd5f75b8c06a5006d245457a90f2 185 Pfam PF01872 RibD C-terminal domain 4 177 3.5E-17 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_11760 6112bd5f75b8c06a5006d245457a90f2 185 SUPERFAMILY SSF53597 4 183 2.62E-26 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_21490 8ff3d9ebc1a0ab73bd1e13043a123482 148 SMART SM00347 31 129 3.2E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_21490 8ff3d9ebc1a0ab73bd1e13043a123482 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 5.3E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_21490 8ff3d9ebc1a0ab73bd1e13043a123482 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 5.3E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_21490 8ff3d9ebc1a0ab73bd1e13043a123482 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 5.3E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_21490 8ff3d9ebc1a0ab73bd1e13043a123482 148 Pfam PF01047 MarR family 38 96 2.5E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_21490 8ff3d9ebc1a0ab73bd1e13043a123482 148 Gene3D G3DSA:1.10.10.10 3 142 1.0E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_21490 8ff3d9ebc1a0ab73bd1e13043a123482 148 SUPERFAMILY SSF46785 7 142 1.05E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_34885 bec7fa948374ccee6ecb7f5b5e6a0366 262 Pfam PF13490 Putative zinc-finger 10 36 4.9E-5 T 12-10-2018 IPR027383 Putative zinc-finger AFR_34885 bec7fa948374ccee6ecb7f5b5e6a0366 262 Gene3D G3DSA:1.10.10.1320 4 64 2.7E-12 T 12-10-2018 AFR_08385 3fb1390560bf0c2008833305496d6f1c 276 SUPERFAMILY SSF53474 11 268 3.44E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_08385 3fb1390560bf0c2008833305496d6f1c 276 Pfam PF12697 Alpha/beta hydrolase family 46 254 5.1E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_08385 3fb1390560bf0c2008833305496d6f1c 276 Gene3D G3DSA:3.40.50.1820 4 269 2.2E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_08360 e49ae5b8a07ada605c78fcc2dfcd1d81 499 Pfam PF00082 Subtilase family 192 450 5.2E-15 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFR_08360 e49ae5b8a07ada605c78fcc2dfcd1d81 499 Gene3D G3DSA:3.40.50.200 187 485 2.8E-32 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_08360 e49ae5b8a07ada605c78fcc2dfcd1d81 499 SUPERFAMILY SSF52743 177 456 7.72E-31 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFR_36230 de132d42f65cdfba114205d10ac46005 105 Pfam PF02021 Uncharacterised protein family UPF0102 1 88 1.2E-27 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 AFR_36230 de132d42f65cdfba114205d10ac46005 105 SUPERFAMILY SSF52980 3 93 1.74E-18 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_36230 de132d42f65cdfba114205d10ac46005 105 Hamap MF_00048 UPF0102 protein YraN [yraN]. 1 101 17.001 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 AFR_36230 de132d42f65cdfba114205d10ac46005 105 Gene3D G3DSA:3.40.1350.10 1 105 1.1E-31 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFR_30395 babd6a697f5058b17e1e993bc608ce1e 321 Pfam PF12679 ABC-2 family transporter protein 67 314 1.7E-11 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_20545 53e5a44f5f9cb04d32b8adc75934bd1f 369 Gene3D G3DSA:1.25.10.10 182 364 1.9E-16 T 12-10-2018 IPR011989 Armadillo-like helical AFR_12170 ab2f466012fcc3b6b9d732715c6c5fe4 133 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 84 1.1E-24 T 12-10-2018 IPR025161 Putative transposase IS4/IS5 family AFR_27935 209cdfe4a35837cc3d8ec172326d2d1b 225 SUPERFAMILY SSF55931 1 214 5.89E-27 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFR_27935 209cdfe4a35837cc3d8ec172326d2d1b 225 Gene3D G3DSA:3.30.590.20 45 97 1.7E-9 T 12-10-2018 AFR_27935 209cdfe4a35837cc3d8ec172326d2d1b 225 Gene3D G3DSA:3.30.590.20 98 225 2.0E-21 T 12-10-2018 AFR_27935 209cdfe4a35837cc3d8ec172326d2d1b 225 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 51 95 1.1E-6 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFR_01965 b7ec6aaa2749c5b758fd2787a9c8a321 563 SUPERFAMILY SSF56300 62 301 1.34E-18 T 12-10-2018 AFR_01965 b7ec6aaa2749c5b758fd2787a9c8a321 563 Pfam PF00149 Calcineurin-like phosphoesterase 68 273 4.6E-6 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_07395 e73a93453e032a1706475d90a9494e78 127 Pfam PF13279 Thioesterase-like superfamily 3 109 2.2E-16 T 12-10-2018 AFR_07395 e73a93453e032a1706475d90a9494e78 127 Gene3D G3DSA:3.10.129.10 1 127 1.3E-36 T 12-10-2018 AFR_07395 e73a93453e032a1706475d90a9494e78 127 SUPERFAMILY SSF54637 2 125 6.28E-32 T 12-10-2018 IPR029069 HotDog domain superfamily AFR_40405 2a693b8b8c7f561fe8512da6f61f13ec 480 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 209 468 4.9E-34 T 12-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 AFR_40405 2a693b8b8c7f561fe8512da6f61f13ec 480 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 9 104 1.8E-16 T 12-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 AFR_12665 5511302b3da6a14ec2918058e080fbde 110 Pfam PF03795 YCII-related domain 23 106 2.5E-5 T 12-10-2018 IPR005545 YCII-related AFR_12665 5511302b3da6a14ec2918058e080fbde 110 Gene3D G3DSA:3.30.70.1060 1 109 7.3E-11 T 12-10-2018 AFR_12665 5511302b3da6a14ec2918058e080fbde 110 SUPERFAMILY SSF54909 16 108 1.55E-7 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_17965 dfb738c00d0e5f7d05716e1667616968 597 Pfam PF17101 Stealth protein CR1, conserved region 1 243 269 1.1E-13 T 12-10-2018 IPR031358 Stealth protein CR1, conserved region 1 AFR_17965 dfb738c00d0e5f7d05716e1667616968 597 Pfam PF17102 Stealth protein CR3, conserved region 3 435 482 8.5E-16 T 12-10-2018 IPR031357 Stealth protein CR3, conserved region 3 AFR_17965 dfb738c00d0e5f7d05716e1667616968 597 Pfam PF17103 Stealth protein CR4, conserved region 4 511 562 9.4E-17 T 12-10-2018 IPR031356 Stealth protein CR4, conserved region 4 AFR_17965 dfb738c00d0e5f7d05716e1667616968 597 Pfam PF11380 Stealth protein CR2, conserved region 2 284 390 8.7E-45 T 12-10-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 AFR_09395 ca21e26107ed0dc08f26034a000c2d07 141 Pfam PF12270 Cytochrome c oxidase subunit IV 1 136 4.4E-49 T 12-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFR_09395 ca21e26107ed0dc08f26034a000c2d07 141 PIRSF PIRSF017385 1 138 1.2E-49 T 12-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFR_20115 7106eefe900e0d2125279f9425d4494d 178 SUPERFAMILY SSF56235 1 173 3.05E-11 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_20115 7106eefe900e0d2125279f9425d4494d 178 Gene3D G3DSA:3.60.20.10 2 168 8.9E-11 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFR_14735 81640dbedfcfac5921174f1b467fb0c1 299 Gene3D G3DSA:3.40.710.10 1 299 2.9E-74 T 12-10-2018 AFR_14735 81640dbedfcfac5921174f1b467fb0c1 299 SUPERFAMILY SSF56601 5 295 1.06E-35 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_14735 81640dbedfcfac5921174f1b467fb0c1 299 Pfam PF13354 Beta-lactamase enzyme family 28 267 8.2E-42 T 12-10-2018 AFR_10770 f198e87373b966ea51df05c6f0349a8f 220 SUPERFAMILY SSF53137 74 202 5.89E-19 T 12-10-2018 AFR_10770 f198e87373b966ea51df05c6f0349a8f 220 Gene3D G3DSA:3.30.420.60 75 194 4.4E-13 T 12-10-2018 AFR_21625 a56b21f646c6e1e9ff41d18cd1b3fa3e 188 SUPERFAMILY SSF53474 4 186 9.22E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21625 a56b21f646c6e1e9ff41d18cd1b3fa3e 188 Gene3D G3DSA:3.40.50.1820 3 187 4.5E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21625 a56b21f646c6e1e9ff41d18cd1b3fa3e 188 Pfam PF01738 Dienelactone hydrolase family 4 187 1.9E-14 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFR_13600 f4c00800e0557c71a38ce7b7e88defb8 203 Pfam PF13460 NAD(P)H-binding 5 192 1.3E-39 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_13600 f4c00800e0557c71a38ce7b7e88defb8 203 SUPERFAMILY SSF51735 1 197 4.76E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13600 f4c00800e0557c71a38ce7b7e88defb8 203 Gene3D G3DSA:3.40.50.720 1 200 3.3E-42 T 12-10-2018 AFR_02510 65bdf60a7f3c284d7a76f665015e37cf 375 Gene3D G3DSA:1.10.287.1060 5 102 3.0E-6 T 12-10-2018 AFR_26920 d2e163131c4a11551ffd682b2bb58ccd 199 Gene3D G3DSA:3.40.50.300 5 199 3.0E-58 T 12-10-2018 AFR_26920 d2e163131c4a11551ffd682b2bb58ccd 199 SUPERFAMILY SSF52540 11 199 5.84E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26920 d2e163131c4a11551ffd682b2bb58ccd 199 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 199 5.1E-69 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 AFR_26920 d2e163131c4a11551ffd682b2bb58ccd 199 PIRSF PIRSF015617 1 199 2.2E-62 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 AFR_26920 d2e163131c4a11551ffd682b2bb58ccd 199 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 199 7.4E-58 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 AFR_23065 893e824fb9288a1437c43eb6047be99e 150 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 128 4.6E-23 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFR_23065 893e824fb9288a1437c43eb6047be99e 150 Gene3D G3DSA:3.40.50.1240 1 137 1.8E-24 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_23065 893e824fb9288a1437c43eb6047be99e 150 SUPERFAMILY SSF53254 5 139 2.57E-25 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFR_09065 18dd280eec923fee06026156baa22a4d 261 Pfam PF00117 Glutamine amidotransferase class-I 77 186 1.1E-11 T 12-10-2018 IPR017926 Glutamine amidotransferase AFR_09065 18dd280eec923fee06026156baa22a4d 261 Gene3D G3DSA:3.40.50.880 2 236 6.1E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_09065 18dd280eec923fee06026156baa22a4d 261 SUPERFAMILY SSF52317 16 223 1.33E-34 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_17535 8c77bab02ae110f5f1df8cbda809845f 253 Pfam PF01925 Sulfite exporter TauE/SafE 7 247 5.5E-33 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFR_22085 716ec36a6edcc7564c266cc2c3fc8aeb 328 Gene3D G3DSA:3.20.20.100 2 327 1.4E-111 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_22085 716ec36a6edcc7564c266cc2c3fc8aeb 328 Pfam PF00248 Aldo/keto reductase family 15 308 3.6E-72 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_22085 716ec36a6edcc7564c266cc2c3fc8aeb 328 SUPERFAMILY SSF51430 3 307 9.17E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_04080 93c729171534e88d6963fea084670fd3 70 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFR_04080 93c729171534e88d6963fea084670fd3 70 SUPERFAMILY SSF55008 3 67 4.32E-18 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFR_04080 93c729171534e88d6963fea084670fd3 70 PRINTS PR00944 Copper ion binding protein signature 16 29 3.2E-6 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 AFR_04080 93c729171534e88d6963fea084670fd3 70 PRINTS PR00944 Copper ion binding protein signature 54 67 3.2E-6 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 AFR_04080 93c729171534e88d6963fea084670fd3 70 PRINTS PR00944 Copper ion binding protein signature 29 42 3.2E-6 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 AFR_04080 93c729171534e88d6963fea084670fd3 70 PRINTS PR00944 Copper ion binding protein signature 4 16 3.2E-6 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 AFR_04080 93c729171534e88d6963fea084670fd3 70 Pfam PF00403 Heavy-metal-associated domain 6 66 5.7E-17 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFR_04080 93c729171534e88d6963fea084670fd3 70 Gene3D G3DSA:3.30.70.100 5 66 8.1E-21 T 12-10-2018 AFR_41275 dd3d3ce9aa06d2e4c09463a02b8eacba 230 SUPERFAMILY SSF53448 11 227 9.18E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_41275 dd3d3ce9aa06d2e4c09463a02b8eacba 230 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 106 113 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFR_41275 dd3d3ce9aa06d2e4c09463a02b8eacba 230 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 13 227 1.6E-64 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFR_41275 dd3d3ce9aa06d2e4c09463a02b8eacba 230 Gene3D G3DSA:3.90.550.10 3 229 8.2E-67 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_41275 dd3d3ce9aa06d2e4c09463a02b8eacba 230 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 228 4.1E-64 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFR_41275 dd3d3ce9aa06d2e4c09463a02b8eacba 230 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 10 227 40.018 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFR_39915 51c68e5f5e92a0187957d5053a9571aa 120 Pfam PF09723 Zinc ribbon domain 2 40 7.5E-14 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFR_39915 51c68e5f5e92a0187957d5053a9571aa 120 SMART SM00834 2 41 4.0E-13 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFR_39915 51c68e5f5e92a0187957d5053a9571aa 120 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 5.9E-19 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFR_15280 0009ef8d70124cdba67591753cb3594b 151 Pfam PF01638 HxlR-like helix-turn-helix 52 142 7.2E-23 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_15280 0009ef8d70124cdba67591753cb3594b 151 Gene3D G3DSA:1.10.10.10 32 151 1.8E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15280 0009ef8d70124cdba67591753cb3594b 151 SUPERFAMILY SSF46785 38 149 1.9E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_03875 76adedbd4cc10335edd88886b6959669 374 SUPERFAMILY SSF89796 1 371 1.83E-127 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily AFR_03875 76adedbd4cc10335edd88886b6959669 374 Gene3D G3DSA:3.30.1540.10 223 314 1.4E-127 T 12-10-2018 AFR_03875 76adedbd4cc10335edd88886b6959669 374 Pfam PF02515 CoA-transferase family III 4 363 1.1E-116 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 AFR_03875 76adedbd4cc10335edd88886b6959669 374 Gene3D G3DSA:3.40.50.10540 3 347 1.4E-127 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily AFR_06700 5d19d5053c1b6cd8f220c15a557e5428 165 SUPERFAMILY SSF50447 74 154 3.21E-5 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFR_03605 2da4d9760ebf2aaf90fafa6159addec5 100 Pfam PF12277 Protein of unknown function (DUF3618) 15 59 4.6E-14 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 AFR_25380 285f41f59181ffd30f490b9ae2922222 359 SUPERFAMILY SSF52266 12 216 1.83E-30 T 12-10-2018 AFR_25380 285f41f59181ffd30f490b9ae2922222 359 Gene3D G3DSA:2.80.10.50 234 358 3.1E-42 T 12-10-2018 AFR_25380 285f41f59181ffd30f490b9ae2922222 359 SUPERFAMILY SSF50370 227 356 1.76E-38 T 12-10-2018 IPR035992 Ricin B-like lectins AFR_25380 285f41f59181ffd30f490b9ae2922222 359 SMART SM00458 231 359 1.1E-29 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_25380 285f41f59181ffd30f490b9ae2922222 359 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 32 205 5.0E-17 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_25380 285f41f59181ffd30f490b9ae2922222 359 Pfam PF00652 Ricin-type beta-trefoil lectin domain 235 356 6.7E-27 T 12-10-2018 IPR000772 Ricin B, lectin domain AFR_25380 285f41f59181ffd30f490b9ae2922222 359 Gene3D G3DSA:3.40.50.1110 23 228 1.2E-64 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_11995 eead47e5b34639a78bfd8c1354cfbf60 412 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 16 392 1.3E-63 T 12-10-2018 IPR010640 Low temperature requirement A AFR_33575 c87e9478c8ce3b2dedfb702a5eb0083e 166 Pfam PF02627 Carboxymuconolactone decarboxylase family 22 77 1.8E-6 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_33575 c87e9478c8ce3b2dedfb702a5eb0083e 166 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 39 77 4.3E-8 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_33575 c87e9478c8ce3b2dedfb702a5eb0083e 166 Gene3D G3DSA:1.20.1290.10 40 152 2.0E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_33575 c87e9478c8ce3b2dedfb702a5eb0083e 166 SUPERFAMILY SSF69118 8 144 1.24E-33 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_28460 c703d0b91c9441e9d6ca857d68ecebc7 131 Pfam PF14430 Immunity protein Imm1 11 130 4.9E-22 T 12-10-2018 IPR025680 Immunity protein Imm1 AFR_10590 e7f3f53750782cec4b7ce77c0b0d606d 202 Pfam PF00583 Acetyltransferase (GNAT) family 52 184 9.3E-8 T 12-10-2018 IPR000182 GNAT domain AFR_10590 e7f3f53750782cec4b7ce77c0b0d606d 202 SUPERFAMILY SSF55729 5 189 1.72E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_10590 e7f3f53750782cec4b7ce77c0b0d606d 202 Gene3D G3DSA:3.40.630.30 2 202 1.3E-68 T 12-10-2018 AFR_04620 6094e90d622f2cabc51b33f85a6bc281 145 Pfam PF08044 Domain of unknown function (DUF1707) 6 58 4.3E-21 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 AFR_40315 5f63a5fb595919dd869a3d8ee15d2792 434 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 14 421 51.428 T 12-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 AFR_40315 5f63a5fb595919dd869a3d8ee15d2792 434 Gene3D G3DSA:3.40.50.2000 19 413 3.7E-132 T 12-10-2018 AFR_40315 5f63a5fb595919dd869a3d8ee15d2792 434 Pfam PF00534 Glycosyl transferases group 1 225 389 2.2E-37 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFR_40315 5f63a5fb595919dd869a3d8ee15d2792 434 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 15 417 1.6E-191 T 12-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 AFR_40315 5f63a5fb595919dd869a3d8ee15d2792 434 Pfam PF13439 Glycosyltransferase Family 4 34 214 2.8E-32 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFR_40315 5f63a5fb595919dd869a3d8ee15d2792 434 SUPERFAMILY SSF53756 33 416 7.33E-87 T 12-10-2018 AFR_40315 5f63a5fb595919dd869a3d8ee15d2792 434 Gene3D G3DSA:3.40.50.2000 211 397 3.7E-132 T 12-10-2018 AFR_20160 49695cdb45686c34000de343ad43e313 329 Pfam PF00877 NlpC/P60 family 228 319 2.1E-21 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFR_20160 49695cdb45686c34000de343ad43e313 329 SUPERFAMILY SSF54001 213 327 2.89E-34 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFR_20160 49695cdb45686c34000de343ad43e313 329 Gene3D G3DSA:3.90.1720.10 142 327 4.0E-42 T 12-10-2018 AFR_38770 67f982f2dba5975dda9555818cff2af7 552 Pfam PF04294 VanW like protein 347 475 4.1E-44 T 12-10-2018 IPR007391 Vancomycin resistance VanW AFR_38770 67f982f2dba5975dda9555818cff2af7 552 Pfam PF12229 Putative peptidoglycan binding domain 201 305 8.1E-8 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain AFR_37900 3227adcf17d799a96835d38fd35796bb 351 SMART SM00563 129 276 0.0053 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_37900 3227adcf17d799a96835d38fd35796bb 351 Pfam PF01553 Acyltransferase 126 263 4.9E-9 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_37900 3227adcf17d799a96835d38fd35796bb 351 SUPERFAMILY SSF69593 88 223 2.75E-6 T 12-10-2018 AFR_16725 04319dc954dc6913e2971979e6e55968 401 Pfam PF12704 MacB-like periplasmic core domain 27 215 7.1E-13 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_16725 04319dc954dc6913e2971979e6e55968 401 Pfam PF02687 FtsX-like permease family 309 395 1.7E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_37230 b0ba9752c122edfb68dafc8e82977f35 386 Pfam PF01594 AI-2E family transporter 66 377 1.1E-52 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFR_32365 b79ee84061e09655fe1d885b2d792ba2 277 Pfam PF01734 Patatin-like phospholipase 6 196 5.7E-18 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFR_32365 b79ee84061e09655fe1d885b2d792ba2 277 Gene3D G3DSA:3.40.1090.10 1 75 9.0E-12 T 12-10-2018 AFR_32365 b79ee84061e09655fe1d885b2d792ba2 277 Gene3D G3DSA:3.40.1090.10 116 238 8.5E-14 T 12-10-2018 AFR_32365 b79ee84061e09655fe1d885b2d792ba2 277 SUPERFAMILY SSF52151 3 205 5.23E-30 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFR_15740 8d6d2f08f2ad0f7ca917177195f83050 187 SUPERFAMILY SSF69118 1 186 2.64E-23 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_15740 8d6d2f08f2ad0f7ca917177195f83050 187 Pfam PF02627 Carboxymuconolactone decarboxylase family 54 124 6.8E-8 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFR_15740 8d6d2f08f2ad0f7ca917177195f83050 187 Gene3D G3DSA:1.20.1290.10 49 187 5.8E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFR_01935 32a09eaea587699f3f2d98c679935434 108 SUPERFAMILY SSF82607 26 101 1.83E-5 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFR_30495 61d59ea746edf84da630fd58e1e2887c 246 Pfam PF00005 ABC transporter 18 166 2.2E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_30495 61d59ea746edf84da630fd58e1e2887c 246 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_30495 61d59ea746edf84da630fd58e1e2887c 246 SMART SM00382 27 214 1.5E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_30495 61d59ea746edf84da630fd58e1e2887c 246 PIRSF PIRSF039085 1 242 1.2E-99 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFR_30495 61d59ea746edf84da630fd58e1e2887c 246 Gene3D G3DSA:3.40.50.300 2 241 2.5E-77 T 12-10-2018 AFR_30495 61d59ea746edf84da630fd58e1e2887c 246 SUPERFAMILY SSF52540 2 236 9.0E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38710 da00e3f357a00ddcc5ee273b2824394d 422 Pfam PF14362 Domain of unknown function (DUF4407) 15 331 1.6E-64 T 12-10-2018 IPR025519 Protein of unknown function DUF4407 AFR_02765 f749bf594fe7b14431770cdbe38caeb8 437 SUPERFAMILY SSF55874 321 437 4.19E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_02765 f749bf594fe7b14431770cdbe38caeb8 437 Pfam PF13796 Putative sensor 30 215 6.1E-44 T 12-10-2018 IPR025828 Putative sensor domain AFR_02765 f749bf594fe7b14431770cdbe38caeb8 437 Pfam PF07730 Histidine kinase 251 314 1.7E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_02765 f749bf594fe7b14431770cdbe38caeb8 437 Gene3D G3DSA:3.30.565.10 320 437 1.1E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_28080 46e0afbba56f85472a173ad4b925cd45 265 Pfam PF07920 Protein of unknown function (DUF1684) 119 257 1.1E-44 T 12-10-2018 IPR012467 Protein of unknown function DUF1684 AFR_08120 32be9f2a5866b47af7b11cf7c7241468 380 Gene3D G3DSA:1.10.1200.80 265 332 7.9E-10 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 AFR_08120 32be9f2a5866b47af7b11cf7c7241468 380 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 19 331 3.3E-111 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 AFR_08120 32be9f2a5866b47af7b11cf7c7241468 380 PIRSF PIRSF006621 11 343 5.4E-103 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFR_08120 32be9f2a5866b47af7b11cf7c7241468 380 Gene3D G3DSA:3.20.20.70 17 261 4.9E-74 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_08120 32be9f2a5866b47af7b11cf7c7241468 380 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 104 122 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFR_08120 32be9f2a5866b47af7b11cf7c7241468 380 Pfam PF01207 Dihydrouridine synthase (Dus) 22 327 4.0E-96 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFR_08120 32be9f2a5866b47af7b11cf7c7241468 380 SUPERFAMILY SSF51395 19 330 9.7E-78 T 12-10-2018 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 SUPERFAMILY SSF50965 43 342 9.42E-45 T 12-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 Pfam PF13964 Kelch motif 261 310 1.0E-10 T 12-10-2018 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 Gene3D G3DSA:2.120.10.80 30 183 4.2E-33 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 Gene3D G3DSA:2.120.10.80 184 339 3.7E-35 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 Pfam PF01344 Kelch motif 47 93 4.0E-7 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 Pfam PF01344 Kelch motif 213 259 1.5E-5 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 Pfam PF01344 Kelch motif 102 148 4.1E-7 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 SMART SM00612 224 272 1.5E-4 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 SMART SM00612 59 111 0.0015 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 SMART SM00612 273 322 0.23 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 SMART SM00612 112 161 8.1E-5 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 AFR_15015 3bdf5839acbc9ddabd2ade79fdfaab63 347 Pfam PF07646 Kelch motif 150 209 1.3E-4 T 12-10-2018 IPR011498 Kelch repeat type 2 GO:0005515 AFR_04055 bae493d1f7de812a8e0301d3ec5d5386 89 Gene3D G3DSA:3.10.450.50 1 85 9.2E-12 T 12-10-2018 AFR_04055 bae493d1f7de812a8e0301d3ec5d5386 89 Pfam PF12680 SnoaL-like domain 2 81 2.4E-10 T 12-10-2018 IPR037401 SnoaL-like domain AFR_04055 bae493d1f7de812a8e0301d3ec5d5386 89 SUPERFAMILY SSF54427 2 82 7.72E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_41710 bb09bf44a98b5662f1547a959af6cfca 386 SMART SM00897 38 232 2.3E-39 T 12-10-2018 IPR013702 FIST domain, N-terminal AFR_41710 bb09bf44a98b5662f1547a959af6cfca 386 Pfam PF10442 FIST C domain 233 368 8.8E-22 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFR_41710 bb09bf44a98b5662f1547a959af6cfca 386 SMART SM01204 233 369 1.2E-23 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFR_41710 bb09bf44a98b5662f1547a959af6cfca 386 Pfam PF08495 FIST N domain 41 231 1.1E-36 T 12-10-2018 IPR013702 FIST domain, N-terminal AFR_41910 d1d51b4031bbc4591118380a770a8474 380 SUPERFAMILY SSF50998 30 364 1.8E-9 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_41910 d1d51b4031bbc4591118380a770a8474 380 Gene3D G3DSA:2.130.10.10 15 375 6.8E-10 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_41910 d1d51b4031bbc4591118380a770a8474 380 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 105 136 0.0076 T 12-10-2018 IPR013431 Delta-60 repeat AFR_10750 5fb71cc34e7bed6216ea55556809f9f4 285 SMART SM00530 17 70 0.0039 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_10750 5fb71cc34e7bed6216ea55556809f9f4 285 Pfam PF13560 Helix-turn-helix domain 14 70 1.2E-7 T 12-10-2018 AFR_10270 cd5be4bc1cb43cf73bd2ca0d2f27414e 245 PIRSF PIRSF006648 2 245 8.7E-20 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_10270 cd5be4bc1cb43cf73bd2ca0d2f27414e 245 Pfam PF01061 ABC-2 type transporter 12 206 2.2E-32 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 Gene3D G3DSA:3.40.50.720 2 228 6.9E-64 T 12-10-2018 AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 SUPERFAMILY SSF51735 3 225 5.37E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 Pfam PF00106 short chain dehydrogenase 3 196 2.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 5.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 5.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_24040 556824dc145d7cf647de6cc2b5f66462 231 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_03090 d522d22dc50f3467171acf724e9d5405 572 SUPERFAMILY SSF53649 308 498 2.88E-9 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_03090 d522d22dc50f3467171acf724e9d5405 572 Gene3D G3DSA:3.40.720.10 248 527 2.7E-15 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_35825 f1cf12927eb4bf2a62eff1c49d88ce7c 137 Pfam PF10722 Putative bacterial sensory transduction regulator 11 135 5.3E-21 T 12-10-2018 IPR019660 Putative sensory transduction regulator YbjN AFR_22920 200b51e9f91da93d5688d18b0dfaebfc 195 Gene3D G3DSA:3.90.1200.10 31 145 4.8E-5 T 12-10-2018 AFR_22920 200b51e9f91da93d5688d18b0dfaebfc 195 SUPERFAMILY SSF56112 6 133 1.15E-14 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_39450 69731260a0382901c355f4bde2b554b2 369 Pfam PF14257 Domain of unknown function (DUF4349) 6 276 5.1E-71 T 12-10-2018 IPR025645 Domain of unknown function DUF4349 AFR_38705 83cc27aaf73ebd2bb7657205997d8d07 171 SUPERFAMILY SSF55144 4 124 3.14E-9 T 12-10-2018 IPR009097 Cyclic phosphodiesterase AFR_38705 83cc27aaf73ebd2bb7657205997d8d07 171 Gene3D G3DSA:3.90.1140.10 4 135 3.2E-6 T 12-10-2018 AFR_17255 bad82d7ffcd3b43629a3b506dbcc5540 233 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 197 206 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 AFR_17255 bad82d7ffcd3b43629a3b506dbcc5540 233 SUPERFAMILY SSF48264 12 212 6.16E-12 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_21535 7073ebffd835fb290541e271d55018b6 559 Gene3D G3DSA:3.40.720.10 235 524 1.9E-14 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_08085 d6cd008a8bf68010e89699bdcd295438 259 SMART SM00382 28 217 7.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_08085 d6cd008a8bf68010e89699bdcd295438 259 Gene3D G3DSA:3.40.50.300 2 230 6.0E-65 T 12-10-2018 AFR_08085 d6cd008a8bf68010e89699bdcd295438 259 Pfam PF00005 ABC transporter 19 167 4.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_08085 d6cd008a8bf68010e89699bdcd295438 259 SUPERFAMILY SSF52540 4 230 1.36E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04260 b4a8c260fe44829497ff07ae2cf70102 125 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 113 2.2E-23 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like AFR_04260 b4a8c260fe44829497ff07ae2cf70102 125 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 121 16.502 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AFR_33765 039fb928f7c6285a137f0b1b10b55930 259 Gene3D G3DSA:1.20.120.1630 87 250 1.5E-10 T 12-10-2018 AFR_33765 039fb928f7c6285a137f0b1b10b55930 259 Pfam PF06966 Protein of unknown function (DUF1295) 19 244 4.7E-69 T 12-10-2018 IPR010721 Protein of unknown function DUF1295 AFR_11020 5ee9faea93ec99d7b43c13f62d2447a5 369 Pfam PF01757 Acyltransferase family 8 321 5.8E-11 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_39125 4b9b2c4f34cf18bc6a3fe582f3dbe4dc 357 Gene3D G3DSA:1.10.260.40 5 90 1.2E-7 T 12-10-2018 AFR_39125 4b9b2c4f34cf18bc6a3fe582f3dbe4dc 357 SUPERFAMILY SSF47413 6 64 7.04E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_39125 4b9b2c4f34cf18bc6a3fe582f3dbe4dc 357 Pfam PF13560 Helix-turn-helix domain 7 64 3.2E-9 T 12-10-2018 AFR_17885 ad583bf93cc2dd951dea8fe0f3a206e0 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 107 1.1E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFR_17885 ad583bf93cc2dd951dea8fe0f3a206e0 129 SUPERFAMILY SSF54593 6 110 2.15E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_17885 ad583bf93cc2dd951dea8fe0f3a206e0 129 Gene3D G3DSA:3.10.180.10 3 116 6.8E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_32020 20bf0c655969d84ed028646596cfcb9c 71 Pfam PF04149 Domain of unknown function (DUF397) 9 58 1.6E-21 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_36020 f9795a657e8d6ff76a69a1b17c549aec 107 Pfam PF13466 STAS domain 23 97 1.7E-12 T 12-10-2018 IPR002645 STAS domain AFR_36020 f9795a657e8d6ff76a69a1b17c549aec 107 Gene3D G3DSA:3.30.750.24 5 101 6.2E-16 T 12-10-2018 IPR036513 STAS domain superfamily AFR_36020 f9795a657e8d6ff76a69a1b17c549aec 107 SUPERFAMILY SSF52091 13 99 2.35E-12 T 12-10-2018 IPR036513 STAS domain superfamily AFR_32805 564065587db1ea40f50fced55d7fa280 207 Pfam PF09997 Predicted membrane protein (DUF2238) 25 172 2.4E-45 T 12-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 AFR_32805 564065587db1ea40f50fced55d7fa280 207 PIRSF PIRSF020606 1 194 2.8E-49 T 12-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 AFR_37225 613a5e7141a05ed8beb45a3581638eab 516 Gene3D G3DSA:1.20.120.20 156 316 2.6E-6 T 12-10-2018 AFR_00785 2b0b4624f8f8a9efb832ca0dcf894feb 258 Gene3D G3DSA:3.40.50.150 54 201 5.6E-19 T 12-10-2018 AFR_00785 2b0b4624f8f8a9efb832ca0dcf894feb 258 Pfam PF13649 Methyltransferase domain 79 169 1.2E-8 T 12-10-2018 AFR_00785 2b0b4624f8f8a9efb832ca0dcf894feb 258 SUPERFAMILY SSF53335 59 243 5.31E-19 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_01870 10c12ec0ae6a6383a2f5a04651f61c2e 102 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 2 101 7.7E-24 T 12-10-2018 IPR021202 Apoptosis inhibitor Rv3654c-like AFR_01870 10c12ec0ae6a6383a2f5a04651f61c2e 102 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 2 41 5.2E-5 T 12-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal AFR_12490 a7b115c9de5d2bd3cbfbedc549f314a0 118 Pfam PF05331 Protein of unknown function (DUF742) 12 118 3.6E-18 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_17470 36000156eaf02843d0f614f891c6c76a 110 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 19 107 6.6E-17 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_17470 36000156eaf02843d0f614f891c6c76a 110 Gene3D G3DSA:3.30.750.24 10 110 5.0E-21 T 12-10-2018 IPR036513 STAS domain superfamily AFR_17470 36000156eaf02843d0f614f891c6c76a 110 SUPERFAMILY SSF52091 19 107 4.51E-18 T 12-10-2018 IPR036513 STAS domain superfamily AFR_17470 36000156eaf02843d0f614f891c6c76a 110 Pfam PF13466 STAS domain 23 103 9.2E-14 T 12-10-2018 IPR002645 STAS domain AFR_39540 247b7fba4edba4c37e30030b0214a836 134 SMART SM00960 8 98 2.0E-30 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_39540 247b7fba4edba4c37e30030b0214a836 134 Pfam PF03259 Roadblock/LC7 domain 8 98 3.1E-22 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFR_39540 247b7fba4edba4c37e30030b0214a836 134 SUPERFAMILY SSF103196 3 127 5.58E-34 T 12-10-2018 AFR_39540 247b7fba4edba4c37e30030b0214a836 134 Gene3D G3DSA:3.30.450.30 3 129 1.5E-44 T 12-10-2018 AFR_37890 60238ea4a7da7fd900776cf157ab5726 259 SUPERFAMILY SSF89392 40 239 2.39E-6 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFR_40800 d37d985453b174c581fa95884dd196d3 208 Pfam PF01865 Protein of unknown function DUF47 12 205 3.2E-23 T 12-10-2018 IPR018445 Putative phosphate transport regulator AFR_40800 d37d985453b174c581fa95884dd196d3 208 Gene3D G3DSA:1.20.58.220 12 208 2.9E-59 T 12-10-2018 IPR038078 PhoU-like domain superfamily AFR_06805 1862c6458bc7fc225d8a4e51cbd50a5c 247 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 117 227 1.0E-18 T 12-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain AFR_36400 f2b10ad0594cd4f59000d6d578dc741d 345 Pfam PF13578 Methyltransferase domain 184 302 1.7E-17 T 12-10-2018 AFR_36400 f2b10ad0594cd4f59000d6d578dc741d 345 SUPERFAMILY SSF53335 162 308 4.31E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_36400 f2b10ad0594cd4f59000d6d578dc741d 345 Gene3D G3DSA:3.40.50.150 132 328 8.8E-25 T 12-10-2018 AFR_29110 43d3b1bc2bdf866ea65bc30d0d4b8ae8 303 Gene3D G3DSA:1.10.3720.10 18 294 1.1E-49 T 12-10-2018 IPR035906 MetI-like superfamily AFR_29110 43d3b1bc2bdf866ea65bc30d0d4b8ae8 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 297 3.2E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_29110 43d3b1bc2bdf866ea65bc30d0d4b8ae8 303 SUPERFAMILY SSF161098 18 302 1.96E-48 T 12-10-2018 IPR035906 MetI-like superfamily AFR_15675 cde9c3150334bea335762a517fbed6a9 313 Gene3D G3DSA:3.20.20.140 177 312 2.8E-8 T 12-10-2018 AFR_15675 cde9c3150334bea335762a517fbed6a9 313 SUPERFAMILY SSF51556 28 310 1.3E-20 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_17815 6b8e4c2759b0f9e0347d114b2198afd7 87 Pfam PF03777 Small secreted domain (DUF320) 44 80 2.6E-8 T 12-10-2018 IPR005528 Domain of unknown function DUF320, Streptomyces species AFR_42405 d62e576cad897e59c9ffd5e024ae7e99 245 Gene3D G3DSA:1.20.120.1760 24 233 4.3E-21 T 12-10-2018 AFR_42405 d62e576cad897e59c9ffd5e024ae7e99 245 Pfam PF01066 CDP-alcohol phosphatidyltransferase 53 129 6.3E-9 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_42405 d62e576cad897e59c9ffd5e024ae7e99 245 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 107 129 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFR_17890 7c61f03d530cc97791dc498f60432812 181 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 62 111 1.1E-8 T 12-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated AFR_17890 7c61f03d530cc97791dc498f60432812 181 SUPERFAMILY SSF53448 8 116 2.33E-6 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_17890 7c61f03d530cc97791dc498f60432812 181 Gene3D G3DSA:3.90.550.10 45 180 1.0E-12 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_22905 0709ca6310135fed458b11b7b8abfdb4 295 SUPERFAMILY SSF53850 89 290 5.61E-40 T 12-10-2018 AFR_22905 0709ca6310135fed458b11b7b8abfdb4 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 8.7E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFR_22905 0709ca6310135fed458b11b7b8abfdb4 295 Gene3D G3DSA:3.40.190.10 165 263 5.0E-54 T 12-10-2018 AFR_22905 0709ca6310135fed458b11b7b8abfdb4 295 SUPERFAMILY SSF46785 2 79 4.84E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_22905 0709ca6310135fed458b11b7b8abfdb4 295 Gene3D G3DSA:3.40.190.10 89 287 5.0E-54 T 12-10-2018 AFR_22905 0709ca6310135fed458b11b7b8abfdb4 295 Gene3D G3DSA:1.10.10.10 1 83 3.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_22905 0709ca6310135fed458b11b7b8abfdb4 295 Pfam PF03466 LysR substrate binding domain 92 292 2.8E-27 T 12-10-2018 IPR005119 LysR, substrate-binding AFR_04290 c671c0cfdebde99a291d53df982cf0da 469 Gene3D G3DSA:1.20.1250.20 13 381 1.2E-23 T 12-10-2018 AFR_04290 c671c0cfdebde99a291d53df982cf0da 469 SUPERFAMILY SSF103473 5 380 3.27E-27 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_04290 c671c0cfdebde99a291d53df982cf0da 469 Pfam PF07690 Major Facilitator Superfamily 15 293 6.1E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_26885 fa779ce83bc41db18bc9cab8d80cc376 98 SUPERFAMILY SSF47413 3 70 3.13E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_26885 fa779ce83bc41db18bc9cab8d80cc376 98 Gene3D G3DSA:1.10.260.40 2 75 3.3E-20 T 12-10-2018 AFR_26885 fa779ce83bc41db18bc9cab8d80cc376 98 SMART SM00530 11 66 2.1E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_26885 fa779ce83bc41db18bc9cab8d80cc376 98 Pfam PF13560 Helix-turn-helix domain 7 67 9.9E-16 T 12-10-2018 AFR_14575 c21798a40d45b6de3d8ad912516984c0 177 SMART SM00347 34 134 8.4E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_14575 c21798a40d45b6de3d8ad912516984c0 177 SUPERFAMILY SSF46785 10 146 3.23E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_14575 c21798a40d45b6de3d8ad912516984c0 177 Gene3D G3DSA:1.10.10.10 8 173 3.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_20015 e541604a4b637f57d08a7e265a93e2ae 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_20015 e541604a4b637f57d08a7e265a93e2ae 189 Gene3D G3DSA:1.10.357.10 1 178 9.5E-26 T 12-10-2018 AFR_20015 e541604a4b637f57d08a7e265a93e2ae 189 SUPERFAMILY SSF46689 2 82 8.72E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_38855 c48179ba7d6908f98c01510b989eef1f 204 SUPERFAMILY SSF51197 21 200 7.69E-40 T 12-10-2018 AFR_38855 c48179ba7d6908f98c01510b989eef1f 204 Gene3D G3DSA:2.60.120.590 36 203 1.1E-37 T 12-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily AFR_38855 c48179ba7d6908f98c01510b989eef1f 204 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 105 190 7.8E-14 T 12-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 Hamap MF_00813 Probable allantoicase [alc]. 1 321 44.679 T 12-10-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 Gene3D G3DSA:2.60.120.260 174 319 2.2E-44 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 SUPERFAMILY SSF49785 174 320 2.68E-44 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 Gene3D G3DSA:2.60.120.260 2 168 1.5E-59 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 PIRSF PIRSF016516 2 323 2.1E-103 T 12-10-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 TIGRFAM TIGR02961 allantoicase: allantoicase 8 319 5.6E-121 T 12-10-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 SUPERFAMILY SSF49785 7 167 4.68E-56 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 Pfam PF03561 Allantoicase repeat 16 163 2.6E-46 T 12-10-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 AFR_31500 c85cf93de756e660ed08e7a0a30276c1 333 Pfam PF03561 Allantoicase repeat 184 318 4.0E-39 T 12-10-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 AFR_02560 b05816aa077665708044e3de797071b8 875 Gene3D G3DSA:3.90.176.10 623 816 6.0E-35 T 12-10-2018 AFR_23520 22a3d2b2f9ed3fa2475a67cce8afa6a4 113 Pfam PF12840 Helix-turn-helix domain 9 68 1.9E-12 T 12-10-2018 AFR_23520 22a3d2b2f9ed3fa2475a67cce8afa6a4 113 SMART SM00418 9 88 1.4E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_23520 22a3d2b2f9ed3fa2475a67cce8afa6a4 113 SUPERFAMILY SSF46785 9 103 2.24E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_23520 22a3d2b2f9ed3fa2475a67cce8afa6a4 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.3E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_23520 22a3d2b2f9ed3fa2475a67cce8afa6a4 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 2.3E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_23520 22a3d2b2f9ed3fa2475a67cce8afa6a4 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 2.3E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFR_23520 22a3d2b2f9ed3fa2475a67cce8afa6a4 113 Gene3D G3DSA:1.10.10.10 7 110 1.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_04365 c11cf767d2e9112001d0b0442372bc35 230 Pfam PF12833 Helix-turn-helix domain 149 220 1.6E-9 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_04365 c11cf767d2e9112001d0b0442372bc35 230 SMART SM00342 135 219 0.0015 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_04365 c11cf767d2e9112001d0b0442372bc35 230 Gene3D G3DSA:1.10.10.60 135 222 9.3E-10 T 12-10-2018 AFR_14390 5c551967b08366f3105161c1668e0816 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 213 6.2E-14 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_14390 5c551967b08366f3105161c1668e0816 293 Gene3D G3DSA:3.40.50.720 2 290 3.5E-39 T 12-10-2018 AFR_14390 5c551967b08366f3105161c1668e0816 293 SUPERFAMILY SSF51735 1 278 2.73E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_39230 7c8c5572919db8ce37ac4d65bffb5607 333 Pfam PF04657 Putative inner membrane exporter, YdcZ 24 167 1.6E-28 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ AFR_39230 7c8c5572919db8ce37ac4d65bffb5607 333 Pfam PF04657 Putative inner membrane exporter, YdcZ 182 315 3.7E-18 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ AFR_36965 f2baf0a417b7eb14a1b47de67d85438c 526 SUPERFAMILY SSF56300 236 453 6.19E-26 T 12-10-2018 AFR_36965 f2baf0a417b7eb14a1b47de67d85438c 526 Pfam PF00149 Calcineurin-like phosphoesterase 238 346 1.8E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_36965 f2baf0a417b7eb14a1b47de67d85438c 526 Gene3D G3DSA:3.60.21.10 237 456 2.1E-14 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_14255 c36822f3ed5ed4592432547f392341d4 289 Pfam PF00535 Glycosyl transferase family 2 1 115 2.1E-14 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_14255 c36822f3ed5ed4592432547f392341d4 289 SUPERFAMILY SSF53448 1 212 6.38E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_14255 c36822f3ed5ed4592432547f392341d4 289 Gene3D G3DSA:3.90.550.10 1 207 6.1E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_06460 00000ddff10266c71bc828c1e4abfbbd 124 SUPERFAMILY SSF54427 2 105 1.8E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_06460 00000ddff10266c71bc828c1e4abfbbd 124 Gene3D G3DSA:3.10.450.50 1 123 1.3E-40 T 12-10-2018 AFR_06460 00000ddff10266c71bc828c1e4abfbbd 124 Pfam PF12680 SnoaL-like domain 4 97 8.6E-9 T 12-10-2018 IPR037401 SnoaL-like domain AFR_21235 5b082982403a3ec9e714595d7abc2109 147 PRINTS PR00502 NUDIX hydrolase family signature 34 48 1.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_21235 5b082982403a3ec9e714595d7abc2109 147 PRINTS PR00502 NUDIX hydrolase family signature 48 63 1.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFR_21235 5b082982403a3ec9e714595d7abc2109 147 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFR_21235 5b082982403a3ec9e714595d7abc2109 147 SUPERFAMILY SSF55811 3 144 9.75E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_21235 5b082982403a3ec9e714595d7abc2109 147 Gene3D G3DSA:3.90.79.10 1 138 1.9E-26 T 12-10-2018 AFR_21235 5b082982403a3ec9e714595d7abc2109 147 Pfam PF00293 NUDIX domain 4 139 8.7E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_40825 af224b98929376005076aa9f15f098ba 417 Pfam PF01594 AI-2E family transporter 71 392 2.7E-66 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFR_03260 fa91a1b1fd6e2e8ce00e719bc058657a 340 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 318 2.9E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_35155 448f5270137322d3b660fa2de2396297 91 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 26 80 1.9E-6 T 12-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 AFR_35155 448f5270137322d3b660fa2de2396297 91 Gene3D G3DSA:2.60.40.10 1 88 1.1E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_35155 448f5270137322d3b660fa2de2396297 91 SUPERFAMILY SSF81296 10 82 2.0E-13 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_32525 b826889814b64ead991b376d1eaf099f 340 SUPERFAMILY SSF51679 14 327 3.14E-54 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_32525 b826889814b64ead991b376d1eaf099f 340 Pfam PF00296 Luciferase-like monooxygenase 28 295 2.4E-32 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_32525 b826889814b64ead991b376d1eaf099f 340 Gene3D G3DSA:3.20.20.30 17 330 2.7E-58 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_32125 0f7350927d6dfca849c3bebf36a62eed 105 Gene3D G3DSA:3.10.180.10 1 102 1.2E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_32125 0f7350927d6dfca849c3bebf36a62eed 105 SUPERFAMILY SSF54593 2 104 2.89E-13 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_08060 8205e1a7656ece990838b47274a0d4ae 175 SUPERFAMILY SSF103473 12 143 7.06E-6 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_08060 8205e1a7656ece990838b47274a0d4ae 175 Gene3D G3DSA:1.20.1250.20 1 174 4.4E-6 T 12-10-2018 AFR_09105 1510ab4e784d12b5f7548a0ec6675759 209 Gene3D G3DSA:2.160.20.100 5 206 5.2E-44 T 12-10-2018 AFR_09105 1510ab4e784d12b5f7548a0ec6675759 209 SUPERFAMILY SSF141571 18 175 9.55E-33 T 12-10-2018 AFR_09105 1510ab4e784d12b5f7548a0ec6675759 209 Pfam PF00805 Pentapeptide repeats (8 copies) 122 157 3.1E-11 T 12-10-2018 IPR001646 Pentapeptide repeat AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 31 535 1.4E-77 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 34 295 1.9E-47 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 SUPERFAMILY SSF53474 15 321 1.05E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 Gene3D G3DSA:3.40.50.1820 28 307 2.5E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 Gene3D G3DSA:2.60.120.260 335 534 6.1E-53 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 Gene3D G3DSA:1.10.3020.10 158 246 2.5E-62 T 12-10-2018 AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 SMART SM00939 310 531 1.0E-53 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 313 530 3.1E-27 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFR_32995 8d5251d5aa0c6ba4ca47e913b7bcc520 535 SUPERFAMILY SSF49785 333 535 8.29E-45 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_25740 fc63e06fd4a8ca7d944b99bc5bb72a3c 395 SUPERFAMILY SSF160631 34 167 2.35E-10 T 12-10-2018 AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 SUPERFAMILY SSF88946 4 75 5.89E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 Pfam PF08281 Sigma-70, region 4 103 156 2.0E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 160 1.5E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 Gene3D G3DSA:1.10.1740.10 2 80 2.8E-10 T 12-10-2018 AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 SUPERFAMILY SSF88659 101 160 1.85E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 162 7.9E-47 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 Gene3D G3DSA:1.10.10.10 81 165 1.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_15255 84f38b9349e72f1500008dbfb14929e7 176 Pfam PF04542 Sigma-70 region 2 19 79 2.6E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_40960 d2fff3fabecf1f85ff3168d05ca9285e 106 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 98 2.0E-5 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 AFR_11120 117695c3513fa7a5de12cafb6a23b709 146 SUPERFAMILY SSF141322 80 140 4.71E-9 T 12-10-2018 AFR_11120 117695c3513fa7a5de12cafb6a23b709 146 Pfam PF01957 NfeD-like C-terminal, partner-binding 2 141 1.1E-21 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain AFR_11120 117695c3513fa7a5de12cafb6a23b709 146 Gene3D G3DSA:2.40.50.140 81 141 5.3E-20 T 12-10-2018 AFR_41350 8429721db32613715d9380ad25750a36 191 Pfam PF14124 Domain of unknown function (DUF4291) 7 167 5.5E-69 T 12-10-2018 IPR025633 Protein of unknown function DUF4291 AFR_27135 2d0597920af787927eaa7850bc2db6fe 182 Gene3D G3DSA:3.40.630.30 1 175 4.0E-52 T 12-10-2018 AFR_27135 2d0597920af787927eaa7850bc2db6fe 182 SUPERFAMILY SSF55729 2 171 3.3E-49 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_27135 2d0597920af787927eaa7850bc2db6fe 182 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 1.9E-33 T 12-10-2018 IPR000182 GNAT domain AFR_20805 0c6e6f688911f31667f5843d3299d839 285 SUPERFAMILY SSF51735 2 185 5.85E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_20805 0c6e6f688911f31667f5843d3299d839 285 Gene3D G3DSA:1.10.1040.10 189 285 2.7E-31 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFR_20805 0c6e6f688911f31667f5843d3299d839 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 183 4.1E-54 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFR_20805 0c6e6f688911f31667f5843d3299d839 285 SUPERFAMILY SSF48179 185 282 3.49E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFR_20805 0c6e6f688911f31667f5843d3299d839 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 1.8E-26 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFR_20805 0c6e6f688911f31667f5843d3299d839 285 Gene3D G3DSA:3.40.50.720 1 188 1.2E-57 T 12-10-2018 AFR_20805 0c6e6f688911f31667f5843d3299d839 285 PIRSF PIRSF000105 1 285 3.6E-77 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFR_16125 7ae837428fa5f8f045b2687832a3d706 351 SUPERFAMILY SSF52540 3 176 8.58E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_27585 626fedfa396994dfe3a1d774c118cbac 377 Gene3D G3DSA:3.40.190.10 41 318 9.5E-53 T 12-10-2018 AFR_27585 626fedfa396994dfe3a1d774c118cbac 377 Pfam PF09084 NMT1/THI5 like 49 268 1.8E-32 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_27585 626fedfa396994dfe3a1d774c118cbac 377 Gene3D G3DSA:3.40.190.10 120 230 9.5E-53 T 12-10-2018 AFR_27585 626fedfa396994dfe3a1d774c118cbac 377 SUPERFAMILY SSF53850 40 268 3.63E-25 T 12-10-2018 AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 2.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 SUPERFAMILY SSF51735 3 218 2.23E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 Gene3D G3DSA:3.40.50.720 2 224 1.2E-60 T 12-10-2018 AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 Pfam PF00106 short chain dehydrogenase 3 189 1.2E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 6.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 6.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_13255 e5c4e1aae5daf9c00b1eb7754f06a9e7 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 6.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_42020 5cb995e6432c7dba925b5e9b54f74a5e 193 SUPERFAMILY SSF46689 3 75 3.64E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_42020 5cb995e6432c7dba925b5e9b54f74a5e 193 Gene3D G3DSA:1.10.357.10 53 189 5.1E-29 T 12-10-2018 AFR_42020 5cb995e6432c7dba925b5e9b54f74a5e 193 Gene3D G3DSA:1.10.10.60 2 51 4.0E-20 T 12-10-2018 AFR_42020 5cb995e6432c7dba925b5e9b54f74a5e 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 56 6.3E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_20340 7ecf9ac51930c44c81aef82291655a44 242 Gene3D G3DSA:2.60.40.2230 25 188 2.7E-53 T 12-10-2018 IPR038507 YcnI-like superfamily AFR_20340 7ecf9ac51930c44c81aef82291655a44 242 Pfam PF07987 Domain of unkown function (DUF1775) 28 175 1.7E-51 T 12-10-2018 IPR012533 YcnI-like AFR_09915 8d2c88178a5d8292ae4f980bbe0c84ca 128 Pfam PF11239 Protein of unknown function (DUF3040) 1 79 4.7E-25 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 AFR_00830 2ebdabee43c0f406f6f877cef8d2d436 142 SUPERFAMILY SSF55874 48 128 7.62E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_00830 2ebdabee43c0f406f6f877cef8d2d436 142 Gene3D G3DSA:3.30.565.10 14 142 6.8E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_14340 8aade1ffe60376a78ed3ce8d96892d85 178 Gene3D G3DSA:3.40.630.30 10 172 6.0E-29 T 12-10-2018 AFR_14340 8aade1ffe60376a78ed3ce8d96892d85 178 Pfam PF13302 Acetyltransferase (GNAT) domain 23 157 3.6E-16 T 12-10-2018 IPR000182 GNAT domain AFR_14340 8aade1ffe60376a78ed3ce8d96892d85 178 SUPERFAMILY SSF55729 22 159 4.03E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_42625 5288b77446c216a0c7c5092ba51519ed 365 Gene3D G3DSA:3.30.1460.10 212 343 1.4E-6 T 12-10-2018 AFR_42625 5288b77446c216a0c7c5092ba51519ed 365 SUPERFAMILY SSF69635 210 336 8.16E-23 T 12-10-2018 AFR_06900 1dd3b5542c8c4a274ddeb8fb1c930a7c 271 Gene3D G3DSA:3.30.750.24 12 131 4.4E-5 T 12-10-2018 IPR036513 STAS domain superfamily AFR_06900 1dd3b5542c8c4a274ddeb8fb1c930a7c 271 SUPERFAMILY SSF55874 167 258 6.59E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_06900 1dd3b5542c8c4a274ddeb8fb1c930a7c 271 Gene3D G3DSA:3.30.565.10 136 265 5.6E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_00210 8a14529bde13983a35f9aad07eaf93d9 192 Pfam PF04264 YceI-like domain 22 188 1.2E-45 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFR_00210 8a14529bde13983a35f9aad07eaf93d9 192 Gene3D G3DSA:2.40.128.110 21 192 4.4E-50 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily AFR_00210 8a14529bde13983a35f9aad07eaf93d9 192 SUPERFAMILY SSF101874 20 191 1.16E-53 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily AFR_00210 8a14529bde13983a35f9aad07eaf93d9 192 SMART SM00867 21 189 9.8E-65 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFR_04770 098d2c7378192c82daf4fb24922c30d1 120 Pfam PF05331 Protein of unknown function (DUF742) 8 120 5.8E-29 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_08910 f89af40825c15452e1e03c87cb7b635d 78 Pfam PF11755 Protein of unknown function (DUF3311) 13 69 1.6E-13 T 12-10-2018 IPR021741 Protein of unknown function DUF3311 AFR_25900 b098bedc4ccf1887de5fc849b53ca35d 254 Pfam PF12697 Alpha/beta hydrolase family 7 242 2.4E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_25900 b098bedc4ccf1887de5fc849b53ca35d 254 Gene3D G3DSA:3.40.50.1820 1 252 3.5E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_25900 b098bedc4ccf1887de5fc849b53ca35d 254 SUPERFAMILY SSF53474 3 251 3.38E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_11095 5a9559a704d31a6c9e0183b232b9f6e5 242 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 2 235 1.0E-14 T 12-10-2018 AFR_38110 7c6c325f39b2915476742be53c1c4771 71 SUPERFAMILY SSF51230 4 71 2.36E-20 T 12-10-2018 IPR011053 Single hybrid motif AFR_38110 7c6c325f39b2915476742be53c1c4771 71 Gene3D G3DSA:2.40.50.100 1 70 1.4E-22 T 12-10-2018 AFR_38110 7c6c325f39b2915476742be53c1c4771 71 Pfam PF00364 Biotin-requiring enzyme 11 70 1.9E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFR_23000 5f9d957ea77eeae98d27f557efec6560 238 Pfam PF02517 CAAX protease self-immunity 142 226 2.0E-13 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFR_29570 d1f35d59f4a464f41baa29217a8ad1b5 477 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 71 443 4.2E-52 T 12-10-2018 AFR_29570 d1f35d59f4a464f41baa29217a8ad1b5 477 TIGRFAM TIGR02710 TIGR02710: CRISPR-associated protein, TIGR02710 family 71 442 2.7E-25 T 12-10-2018 IPR014082 CRISPR-associated protein, Cas02710 AFR_29570 d1f35d59f4a464f41baa29217a8ad1b5 477 SUPERFAMILY SSF52980 59 196 1.02E-8 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_23840 16e7b428a27b293013138e9c6a8e1dd9 298 SUPERFAMILY SSF103481 36 123 2.75E-8 T 12-10-2018 AFR_23840 16e7b428a27b293013138e9c6a8e1dd9 298 SUPERFAMILY SSF103481 182 267 3.4E-12 T 12-10-2018 AFR_23840 16e7b428a27b293013138e9c6a8e1dd9 298 Pfam PF00892 EamA-like transporter family 135 265 7.5E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_23840 16e7b428a27b293013138e9c6a8e1dd9 298 Pfam PF00892 EamA-like transporter family 2 121 1.1E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_24450 96461661ea4e07582f7752562ee6f5cc 203 SUPERFAMILY SSF52833 31 190 6.46E-11 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFR_24450 96461661ea4e07582f7752562ee6f5cc 203 Gene3D G3DSA:3.40.30.10 28 182 9.1E-14 T 12-10-2018 AFR_24450 96461661ea4e07582f7752562ee6f5cc 203 Pfam PF00578 AhpC/TSA family 39 170 1.6E-8 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFR_01120 8d23faba2713575a697dacebecf037e8 230 Pfam PF00005 ABC transporter 26 174 5.0E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_01120 8d23faba2713575a697dacebecf037e8 230 Gene3D G3DSA:3.40.50.300 5 228 1.9E-70 T 12-10-2018 AFR_01120 8d23faba2713575a697dacebecf037e8 230 SMART SM00382 35 229 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_01120 8d23faba2713575a697dacebecf037e8 230 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_01120 8d23faba2713575a697dacebecf037e8 230 SUPERFAMILY SSF52540 7 224 1.36E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_16875 f66621e39c4e1445343da3169a7fdebb 179 Gene3D G3DSA:3.40.630.30 7 165 6.8E-32 T 12-10-2018 AFR_16875 f66621e39c4e1445343da3169a7fdebb 179 Pfam PF13302 Acetyltransferase (GNAT) domain 18 151 6.0E-18 T 12-10-2018 IPR000182 GNAT domain AFR_16875 f66621e39c4e1445343da3169a7fdebb 179 SUPERFAMILY SSF55729 10 157 6.16E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_14795 c7fffbf119dbf8e81ad36d3f1fb230f3 139 Pfam PF13564 DoxX-like family 21 116 1.8E-14 T 12-10-2018 IPR032808 DoxX family AFR_38375 6495f5a79f7dbfe75f41e424689b2a1c 405 Gene3D G3DSA:3.30.565.10 267 398 3.3E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38375 6495f5a79f7dbfe75f41e424689b2a1c 405 Pfam PF07730 Histidine kinase 199 262 9.8E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_38375 6495f5a79f7dbfe75f41e424689b2a1c 405 SUPERFAMILY SSF55874 281 396 1.83E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41695 3bb473ca74788f193c4ca91897dd7e9d 399 Gene3D G3DSA:1.20.1250.20 3 388 5.4E-42 T 12-10-2018 AFR_41695 3bb473ca74788f193c4ca91897dd7e9d 399 SUPERFAMILY SSF103473 5 388 2.22E-45 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_41695 3bb473ca74788f193c4ca91897dd7e9d 399 Pfam PF05977 Transmembrane secretion effector 5 389 6.3E-31 T 12-10-2018 IPR010290 Transmembrane secretion effector AFR_09810 e1080e41ad671c9dcdcea6755756ae9b 446 Gene3D G3DSA:3.30.870.10 49 232 3.9E-14 T 12-10-2018 AFR_09810 e1080e41ad671c9dcdcea6755756ae9b 446 Gene3D G3DSA:3.30.870.10 290 418 5.1E-15 T 12-10-2018 AFR_09810 e1080e41ad671c9dcdcea6755756ae9b 446 SUPERFAMILY SSF56024 291 411 3.59E-13 T 12-10-2018 AFR_09810 e1080e41ad671c9dcdcea6755756ae9b 446 SUPERFAMILY SSF56024 55 227 4.97E-10 T 12-10-2018 AFR_09810 e1080e41ad671c9dcdcea6755756ae9b 446 Pfam PF13091 PLD-like domain 71 224 3.6E-9 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFR_09810 e1080e41ad671c9dcdcea6755756ae9b 446 Pfam PF13091 PLD-like domain 291 409 5.2E-9 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFR_02355 eda0ad11f99834b4990a2157c7e143b9 301 Pfam PF09362 Domain of unknown function (DUF1996) 77 255 1.1E-20 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_08840 1c9c418e50084bffad7c0a5998f04521 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 188 1.2E-29 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_08840 1c9c418e50084bffad7c0a5998f04521 211 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 94 3.7E-11 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_08840 1c9c418e50084bffad7c0a5998f04521 211 SUPERFAMILY SSF109854 3 125 6.41E-16 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_08840 1c9c418e50084bffad7c0a5998f04521 211 Gene3D G3DSA:1.20.120.450 1 99 3.1E-9 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_39500 e596739ec5f8f294282ea854d96ac938 316 SUPERFAMILY SSF51569 58 296 8.48E-78 T 12-10-2018 AFR_39500 e596739ec5f8f294282ea854d96ac938 316 Pfam PF01791 DeoC/LacD family aldolase 53 294 2.4E-26 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_39500 e596739ec5f8f294282ea854d96ac938 316 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 59 278 5.8E-56 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_39500 e596739ec5f8f294282ea854d96ac938 316 PIRSF PIRSF001357 51 306 3.4E-83 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_39500 e596739ec5f8f294282ea854d96ac938 316 Gene3D G3DSA:3.20.20.70 47 301 5.6E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_39500 e596739ec5f8f294282ea854d96ac938 316 SMART SM01133 57 297 3.6E-81 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFR_30790 fc59178b52dd9ad5fb35c07f986e428a 507 Pfam PF12679 ABC-2 family transporter protein 299 506 6.6E-8 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_30790 fc59178b52dd9ad5fb35c07f986e428a 507 Gene3D G3DSA:2.60.120.200 107 220 2.6E-10 T 12-10-2018 AFR_15165 7d17494718aa65b98ef13e82f1c86c04 313 PIRSF PIRSF016660 1 307 2.0E-113 T 12-10-2018 IPR008526 Inner membrane protein YedI AFR_15165 7d17494718aa65b98ef13e82f1c86c04 313 Pfam PF05661 Protein of unknown function (DUF808) 4 296 8.1E-124 T 12-10-2018 IPR008526 Inner membrane protein YedI AFR_23500 469a08030d9a3b59af40bffe107826b9 342 SUPERFAMILY SSF51735 1 337 1.71E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_23500 469a08030d9a3b59af40bffe107826b9 342 PRINTS PR01713 Nucleotide sugar epimerase signature 243 258 2.7E-5 T 12-10-2018 AFR_23500 469a08030d9a3b59af40bffe107826b9 342 PRINTS PR01713 Nucleotide sugar epimerase signature 305 322 2.7E-5 T 12-10-2018 AFR_23500 469a08030d9a3b59af40bffe107826b9 342 PRINTS PR01713 Nucleotide sugar epimerase signature 266 281 2.7E-5 T 12-10-2018 AFR_23500 469a08030d9a3b59af40bffe107826b9 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 272 6.4E-45 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_23500 469a08030d9a3b59af40bffe107826b9 342 Gene3D G3DSA:3.40.50.720 162 272 2.5E-43 T 12-10-2018 AFR_23500 469a08030d9a3b59af40bffe107826b9 342 Gene3D G3DSA:3.40.50.720 1 155 1.3E-26 T 12-10-2018 AFR_23500 469a08030d9a3b59af40bffe107826b9 342 Gene3D G3DSA:3.90.25.10 207 335 2.5E-43 T 12-10-2018 AFR_29355 aaf00dab5965d0852e68866430faba1f 525 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 54 258 3.9E-14 T 12-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 AFR_29355 aaf00dab5965d0852e68866430faba1f 525 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 328 522 7.7E-17 T 12-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 AFR_19300 24003b89206d592d7113e708a606b047 321 SUPERFAMILY SSF53850 47 270 5.99E-39 T 12-10-2018 AFR_19300 24003b89206d592d7113e708a606b047 321 Pfam PF09084 NMT1/THI5 like 47 263 4.0E-39 T 12-10-2018 IPR015168 SsuA/THI5-like AFR_19300 24003b89206d592d7113e708a606b047 321 Gene3D G3DSA:3.40.190.10 35 147 8.2E-15 T 12-10-2018 AFR_19300 24003b89206d592d7113e708a606b047 321 Gene3D G3DSA:3.40.190.10 148 305 9.2E-27 T 12-10-2018 AFR_24775 450659c7516ca1e9f5e3bbdc7be70a99 248 Pfam PF04248 Domain of unknown function (DUF427) 21 94 1.1E-7 T 12-10-2018 IPR007361 Domain of unknown function DUF427 AFR_24775 450659c7516ca1e9f5e3bbdc7be70a99 248 Pfam PF04248 Domain of unknown function (DUF427) 136 229 7.7E-28 T 12-10-2018 IPR007361 Domain of unknown function DUF427 AFR_24775 450659c7516ca1e9f5e3bbdc7be70a99 248 Gene3D G3DSA:2.170.150.40 11 94 2.1E-5 T 12-10-2018 AFR_24775 450659c7516ca1e9f5e3bbdc7be70a99 248 Gene3D G3DSA:2.170.150.40 122 235 4.0E-31 T 12-10-2018 AFR_06795 b9a3e6fc5e3b690621ed131ddf84d798 465 Gene3D G3DSA:3.40.50.300 209 439 3.4E-74 T 12-10-2018 AFR_06795 b9a3e6fc5e3b690621ed131ddf84d798 465 SUPERFAMILY SSF52540 100 396 4.3E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06795 b9a3e6fc5e3b690621ed131ddf84d798 465 Gene3D G3DSA:3.30.450.380 29 208 1.0E-42 T 12-10-2018 AFR_06795 b9a3e6fc5e3b690621ed131ddf84d798 465 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 310 324 - T 12-10-2018 IPR001482 Type II/IV secretion system protein AFR_06795 b9a3e6fc5e3b690621ed131ddf84d798 465 Pfam PF00437 Type II/IV secretion system protein 113 389 1.5E-83 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFR_05605 0e34b9becfb54c11054f6531ec560619 659 Pfam PF13646 HEAT repeats 238 307 1.5E-6 T 12-10-2018 AFR_05605 0e34b9becfb54c11054f6531ec560619 659 Gene3D G3DSA:1.25.10.10 205 352 5.7E-6 T 12-10-2018 IPR011989 Armadillo-like helical AFR_05605 0e34b9becfb54c11054f6531ec560619 659 SUPERFAMILY SSF48371 26 638 4.03E-9 T 12-10-2018 IPR016024 Armadillo-type fold AFR_31910 f5b2b57f8b6d5091fb021ddc04e0f5de 346 Pfam PF09949 Uncharacterized conserved protein (DUF2183) 202 298 1.3E-30 T 12-10-2018 IPR019236 Domain of unknown function DUF2183 AFR_02645 7cd956e26411a071e7f2f8666aa237aa 80 Pfam PF13657 HipA N-terminal domain 5 79 8.6E-15 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 AFR_02645 7cd956e26411a071e7f2f8666aa237aa 80 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 4 80 9.4E-18 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 AFR_15575 5dd6857d9813c9f58e7bbf1d20d616ca 252 Gene3D G3DSA:3.40.630.30 1 252 1.7E-26 T 12-10-2018 AFR_15575 5dd6857d9813c9f58e7bbf1d20d616ca 252 SUPERFAMILY SSF55729 96 249 3.49E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_15575 5dd6857d9813c9f58e7bbf1d20d616ca 252 Pfam PF08445 FR47-like protein 182 242 7.4E-5 T 12-10-2018 IPR013653 FR47-like GO:0016747 AFR_03110 a88471c542c37d7aed3e958a1debbca6 185 Gene3D G3DSA:2.60.40.1220 27 126 1.8E-26 T 12-10-2018 AFR_03110 a88471c542c37d7aed3e958a1debbca6 185 SUPERFAMILY SSF81296 26 120 1.96E-20 T 12-10-2018 IPR014756 Immunoglobulin E-set AFR_03110 a88471c542c37d7aed3e958a1debbca6 185 Pfam PF04234 CopC domain 27 120 1.8E-22 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 AFR_08480 229cafa4f0ac1ac7dcafff7e67bd68fb 270 Gene3D G3DSA:3.40.50.150 2 228 5.2E-32 T 12-10-2018 AFR_08480 229cafa4f0ac1ac7dcafff7e67bd68fb 270 Pfam PF13649 Methyltransferase domain 49 141 8.0E-19 T 12-10-2018 AFR_08480 229cafa4f0ac1ac7dcafff7e67bd68fb 270 SUPERFAMILY SSF53335 22 225 2.94E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_07970 844b1752fca6dd62e5fdd68149f32b6c 123 Gene3D G3DSA:3.40.140.10 13 121 1.0E-8 T 12-10-2018 AFR_07970 844b1752fca6dd62e5fdd68149f32b6c 123 SUPERFAMILY SSF53927 19 89 1.24E-8 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFR_06330 b7c609c0bc4182b8b773c00a73b4bb0f 168 Pfam PF09438 Domain of unknown function (DUF2017) 39 162 4.6E-35 T 12-10-2018 IPR018561 Domain of unknown function DUF2017 AFR_08485 2f4b3c156e06cbe3694740eac5ce68f3 159 Gene3D G3DSA:3.30.530.20 12 159 7.8E-21 T 12-10-2018 IPR023393 START-like domain superfamily AFR_08485 2f4b3c156e06cbe3694740eac5ce68f3 159 SUPERFAMILY SSF55961 13 152 6.09E-19 T 12-10-2018 AFR_08485 2f4b3c156e06cbe3694740eac5ce68f3 159 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 151 8.2E-19 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_27280 6bf49b0449d02a83a60cd6b07b1feeb0 241 Pfam PF13672 Protein phosphatase 2C 26 202 1.6E-12 T 12-10-2018 AFR_27280 6bf49b0449d02a83a60cd6b07b1feeb0 241 SMART SM00331 8 234 7.3E-11 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27280 6bf49b0449d02a83a60cd6b07b1feeb0 241 SUPERFAMILY SSF81606 6 234 2.49E-42 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27280 6bf49b0449d02a83a60cd6b07b1feeb0 241 Gene3D G3DSA:3.60.40.10 3 235 2.0E-41 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_27280 6bf49b0449d02a83a60cd6b07b1feeb0 241 SMART SM00332 5 232 2.5E-5 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFR_29555 7239a1f520956aea62de07ed5079a092 515 Pfam PF13091 PLD-like domain 254 386 3.1E-11 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFR_29555 7239a1f520956aea62de07ed5079a092 515 Pfam PF13091 PLD-like domain 66 204 9.1E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFR_29555 7239a1f520956aea62de07ed5079a092 515 SUPERFAMILY SSF56024 58 213 8.37E-23 T 12-10-2018 AFR_29555 7239a1f520956aea62de07ed5079a092 515 Gene3D G3DSA:3.30.870.10 39 207 1.9E-22 T 12-10-2018 AFR_29555 7239a1f520956aea62de07ed5079a092 515 Gene3D G3DSA:3.30.870.10 231 391 1.4E-16 T 12-10-2018 AFR_29555 7239a1f520956aea62de07ed5079a092 515 SUPERFAMILY SSF56024 245 389 4.49E-16 T 12-10-2018 AFR_22640 67762a7bdcb9ae9cac74a602ae11928d 460 Gene3D G3DSA:3.40.720.10 1 266 4.4E-41 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFR_22640 67762a7bdcb9ae9cac74a602ae11928d 460 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 369 3.1E-60 T 12-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 AFR_22640 67762a7bdcb9ae9cac74a602ae11928d 460 Gene3D G3DSA:3.30.1360.110 272 349 2.3E-7 T 12-10-2018 IPR023116 Phosphonoacetate hydrolase, insert domain superfamily KEGG: 00440+3.11.1.2 AFR_22640 67762a7bdcb9ae9cac74a602ae11928d 460 SUPERFAMILY SSF53649 2 456 9.16E-77 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFR_19615 1591cbb05d0e7f6c58d79184a4e5d530 337 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 91 127 2.0E-8 T 12-10-2018 IPR014262 Extracellular HAF AFR_29115 b4aec3418a62996795c8b2cb6273dbd0 310 Gene3D G3DSA:1.10.3720.10 64 304 2.1E-40 T 12-10-2018 IPR035906 MetI-like superfamily AFR_29115 b4aec3418a62996795c8b2cb6273dbd0 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 298 1.0E-7 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_29115 b4aec3418a62996795c8b2cb6273dbd0 310 SUPERFAMILY SSF161098 68 298 2.83E-36 T 12-10-2018 IPR035906 MetI-like superfamily AFR_03075 e1136620885af71b37e4144aac142ee9 228 Pfam PF09335 SNARE associated Golgi protein 40 165 3.9E-18 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_24300 ac2792c8d4283e227896ab01af1b0b1a 144 Gene3D G3DSA:3.30.565.10 6 143 9.3E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_24300 ac2792c8d4283e227896ab01af1b0b1a 144 Pfam PF13581 Histidine kinase-like ATPase domain 50 136 4.1E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_24300 ac2792c8d4283e227896ab01af1b0b1a 144 SUPERFAMILY SSF55874 27 128 5.31E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_17315 dd154a4c16e16347ddfd5409efa6513f 219 Pfam PF02687 FtsX-like permease family 125 213 3.0E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_07380 52eb89138cd27cb433fbcc93fa985f88 492 Gene3D G3DSA:3.40.50.2000 29 455 5.9E-163 T 12-10-2018 AFR_07380 52eb89138cd27cb433fbcc93fa985f88 492 Gene3D G3DSA:3.40.50.2000 236 444 5.9E-163 T 12-10-2018 AFR_07380 52eb89138cd27cb433fbcc93fa985f88 492 SUPERFAMILY SSF53756 6 458 1.76E-140 T 12-10-2018 AFR_07380 52eb89138cd27cb433fbcc93fa985f88 492 Pfam PF00982 Glycosyltransferase family 20 6 458 2.5E-143 T 12-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 AFR_17730 d69d3d07a65a44b9b7e1eb1fdab304fa 429 Pfam PF01569 PAP2 superfamily 297 415 1.9E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_17730 d69d3d07a65a44b9b7e1eb1fdab304fa 429 Gene3D G3DSA:1.10.606.20 38 426 1.8E-85 T 12-10-2018 AFR_17730 d69d3d07a65a44b9b7e1eb1fdab304fa 429 SUPERFAMILY SSF48317 28 422 1.83E-76 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_02100 0e459b3f910f788f132dd169da6e3524 128 SUPERFAMILY SSF50249 2 65 1.18E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_02100 0e459b3f910f788f132dd169da6e3524 128 Pfam PF00313 'Cold-shock' DNA-binding domain 3 63 2.0E-13 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_02100 0e459b3f910f788f132dd169da6e3524 128 Gene3D G3DSA:2.40.50.140 3 66 4.4E-17 T 12-10-2018 AFR_02100 0e459b3f910f788f132dd169da6e3524 128 PRINTS PR00050 Cold shock protein signature 24 33 2.8E-9 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_02100 0e459b3f910f788f132dd169da6e3524 128 PRINTS PR00050 Cold shock protein signature 38 56 2.8E-9 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_02100 0e459b3f910f788f132dd169da6e3524 128 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-9 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFR_02100 0e459b3f910f788f132dd169da6e3524 128 SMART SM00357 3 65 6.3E-17 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFR_40850 e740cbc169ed36db6529280b849e133d 212 Gene3D G3DSA:1.10.3210.10 19 175 4.4E-12 T 12-10-2018 AFR_40850 e740cbc169ed36db6529280b849e133d 212 PIRSF PIRSF035170 4 212 3.8E-64 T 12-10-2018 IPR009218 Predicted HD phosphohydrolase AFR_40850 e740cbc169ed36db6529280b849e133d 212 SUPERFAMILY SSF109604 26 201 8.9E-27 T 12-10-2018 AFR_36745 41562a60ae0829168dca94d7ea4598b2 279 SMART SM00342 172 256 0.0023 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_36745 41562a60ae0829168dca94d7ea4598b2 279 Gene3D G3DSA:1.10.10.60 163 262 5.1E-15 T 12-10-2018 AFR_36745 41562a60ae0829168dca94d7ea4598b2 279 Pfam PF12833 Helix-turn-helix domain 182 256 1.6E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFR_25835 0e91b9c0f144cc6e15a86f594756264f 175 Gene3D G3DSA:3.90.79.10 1 173 8.0E-39 T 12-10-2018 AFR_25835 0e91b9c0f144cc6e15a86f594756264f 175 Pfam PF00293 NUDIX domain 42 136 4.1E-6 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_25835 0e91b9c0f144cc6e15a86f594756264f 175 SUPERFAMILY SSF55811 2 173 1.9E-30 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_10885 e3873e19b524a331a1b662372f0cc35f 272 SUPERFAMILY SSF51658 61 210 6.96E-10 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_10885 e3873e19b524a331a1b662372f0cc35f 272 Pfam PF05114 Protein of unknown function (DUF692) 6 265 4.3E-84 T 12-10-2018 IPR007801 Uncharacterised protein family UPF0276 AFR_10885 e3873e19b524a331a1b662372f0cc35f 272 Gene3D G3DSA:3.20.20.150 3 269 4.1E-84 T 12-10-2018 AFR_42715 8053d11fc6f7d2bb2258055c15df089d 505 Pfam PF09594 Glycosyltransferase family 87 72 335 2.0E-32 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 AFR_06130 e55bd0311770db9644a034795ef5c809 449 SUPERFAMILY SSF52540 42 404 5.22E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_06130 e55bd0311770db9644a034795ef5c809 449 Pfam PF13604 AAA domain 32 187 7.7E-11 T 12-10-2018 AFR_06130 e55bd0311770db9644a034795ef5c809 449 Gene3D G3DSA:3.40.50.300 278 420 4.6E-12 T 12-10-2018 AFR_06130 e55bd0311770db9644a034795ef5c809 449 Gene3D G3DSA:3.40.50.300 27 212 2.4E-15 T 12-10-2018 AFR_24680 d488842099302e08706db7bce3fb3a09 172 Gene3D G3DSA:3.40.50.300 3 172 1.5E-34 T 12-10-2018 AFR_24680 d488842099302e08706db7bce3fb3a09 172 SUPERFAMILY SSF52540 4 157 8.79E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24680 d488842099302e08706db7bce3fb3a09 172 Pfam PF13671 AAA domain 6 127 2.3E-12 T 12-10-2018 AFR_24680 d488842099302e08706db7bce3fb3a09 172 SMART SM00382 3 130 0.0038 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_17770 11be7fad5acbdef30eab862a1d651f56 108 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 104 5.0E-19 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFR_17770 11be7fad5acbdef30eab862a1d651f56 108 SUPERFAMILY SSF52091 8 105 5.3E-22 T 12-10-2018 IPR036513 STAS domain superfamily AFR_17770 11be7fad5acbdef30eab862a1d651f56 108 Pfam PF13466 STAS domain 21 101 3.4E-16 T 12-10-2018 IPR002645 STAS domain AFR_17770 11be7fad5acbdef30eab862a1d651f56 108 Gene3D G3DSA:3.30.750.24 7 107 1.2E-24 T 12-10-2018 IPR036513 STAS domain superfamily AFR_22480 04c96e6b4f1c2d80fe482af154ee1c97 421 SUPERFAMILY SSF53756 4 417 3.14E-57 T 12-10-2018 AFR_22480 04c96e6b4f1c2d80fe482af154ee1c97 421 Gene3D G3DSA:3.40.50.2000 254 405 2.8E-40 T 12-10-2018 AFR_22480 04c96e6b4f1c2d80fe482af154ee1c97 421 Gene3D G3DSA:3.40.50.2000 2 253 1.3E-14 T 12-10-2018 AFR_22480 04c96e6b4f1c2d80fe482af154ee1c97 421 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 245 395 9.5E-15 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 AFR_00130 4cafd6c1e9b4a0fb42b775f63524a598 272 Pfam PF13490 Putative zinc-finger 8 37 1.2E-6 T 12-10-2018 IPR027383 Putative zinc-finger AFR_00130 4cafd6c1e9b4a0fb42b775f63524a598 272 Gene3D G3DSA:1.10.10.1320 1 42 1.0E-5 T 12-10-2018 AFR_25355 a083b0ef14a80c076e1045ff2d5e6cb0 259 Pfam PF00248 Aldo/keto reductase family 4 257 1.3E-42 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_25355 a083b0ef14a80c076e1045ff2d5e6cb0 259 SUPERFAMILY SSF51430 3 258 1.44E-55 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_25355 a083b0ef14a80c076e1045ff2d5e6cb0 259 Gene3D G3DSA:3.20.20.100 1 259 3.0E-62 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_22050 0940fdd5d2c77244454ae1fa4ae48aa4 308 Gene3D G3DSA:1.20.140.10 159 306 1.5E-6 T 12-10-2018 AFR_22050 0940fdd5d2c77244454ae1fa4ae48aa4 308 SUPERFAMILY SSF56645 38 160 3.93E-13 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFR_22050 0940fdd5d2c77244454ae1fa4ae48aa4 308 Gene3D G3DSA:2.40.110.10 67 156 3.4E-13 T 12-10-2018 AFR_18500 af1633c869bf3efe2fc493d498fc0a8f 301 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 12 294 1.8E-37 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 AFR_18500 af1633c869bf3efe2fc493d498fc0a8f 301 SUPERFAMILY SSF51197 10 295 4.35E-69 T 12-10-2018 AFR_18500 af1633c869bf3efe2fc493d498fc0a8f 301 Gene3D G3DSA:3.60.130.10 2 296 4.2E-84 T 12-10-2018 AFR_35265 db1f0cd6bdd98624cf3fa14919d99271 700 Pfam PF13520 Amino acid permease 73 476 2.4E-27 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFR_35265 db1f0cd6bdd98624cf3fa14919d99271 700 Gene3D G3DSA:1.20.1740.10 68 514 2.5E-16 T 12-10-2018 AFR_25005 8d4074ab913c5b76ce2b4ba47f02a735 315 Pfam PF00535 Glycosyl transferase family 2 10 171 2.2E-21 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_25005 8d4074ab913c5b76ce2b4ba47f02a735 315 SUPERFAMILY SSF53448 5 232 2.81E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_25005 8d4074ab913c5b76ce2b4ba47f02a735 315 Gene3D G3DSA:3.90.550.10 2 225 5.7E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_35455 9bc558b28a4fe4b4ee798536f01b73a1 304 Gene3D G3DSA:3.40.50.1820 1 301 7.3E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_35455 9bc558b28a4fe4b4ee798536f01b73a1 304 SUPERFAMILY SSF53474 5 301 4.19E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_35455 9bc558b28a4fe4b4ee798536f01b73a1 304 Pfam PF12697 Alpha/beta hydrolase family 26 294 2.4E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_41245 cc89dd3f0df2a3ceee9592b9480de747 293 SUPERFAMILY SSF161098 24 293 1.12E-74 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41245 cc89dd3f0df2a3ceee9592b9480de747 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 286 9.6E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_41245 cc89dd3f0df2a3ceee9592b9480de747 293 Gene3D G3DSA:1.10.3720.10 17 280 2.7E-67 T 12-10-2018 IPR035906 MetI-like superfamily AFR_42140 32c790aa1d5a8e837dfae0f019ffd973 386 Pfam PF09362 Domain of unknown function (DUF1996) 141 360 8.5E-48 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_18465 a6c93f60c729f0f56ba98067591b6f3f 265 Gene3D G3DSA:1.10.10.10 117 264 1.3E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_18465 a6c93f60c729f0f56ba98067591b6f3f 265 SUPERFAMILY SSF46894 201 258 8.84E-7 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_25525 312af43d55825184f5499479dd359055 417 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 403 1.4E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_42235 536aac8696a433d9fc9f8aa72acedfbf 113 Pfam PF03795 YCII-related domain 19 109 5.2E-10 T 12-10-2018 IPR005545 YCII-related AFR_42235 536aac8696a433d9fc9f8aa72acedfbf 113 Gene3D G3DSA:3.30.70.1060 2 113 4.2E-30 T 12-10-2018 AFR_42235 536aac8696a433d9fc9f8aa72acedfbf 113 SUPERFAMILY SSF54909 14 112 9.12E-24 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_28090 0c534bc7a120be3a1877754310bba66a 568 Gene3D G3DSA:3.30.830.10 206 363 1.6E-12 T 12-10-2018 AFR_28090 0c534bc7a120be3a1877754310bba66a 568 SUPERFAMILY SSF63411 217 354 1.17E-10 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_28090 0c534bc7a120be3a1877754310bba66a 568 SUPERFAMILY SSF63411 21 171 2.97E-13 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFR_28090 0c534bc7a120be3a1877754310bba66a 568 Gene3D G3DSA:3.30.830.10 8 175 1.8E-11 T 12-10-2018 AFR_00820 15e1d3d426015057354d1b2f4606ecc5 225 Pfam PF10979 Protein of unknown function (DUF2786) 6 45 6.5E-17 T 12-10-2018 IPR024498 Domain of unknown function DUF2786 AFR_00820 15e1d3d426015057354d1b2f4606ecc5 225 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 36 222 7.0E-37 T 12-10-2018 AFR_16905 5cd04175a29d59d00c0223064f374d96 328 SUPERFAMILY SSF51735 1 283 4.84E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_16905 5cd04175a29d59d00c0223064f374d96 328 Gene3D G3DSA:3.40.50.720 3 306 8.6E-27 T 12-10-2018 AFR_36340 f04da9fe9f9b506d5a5e99ba052330e2 216 Pfam PF04167 Protein of unknown function (DUF402) 82 150 8.7E-14 T 12-10-2018 IPR007295 Domain of unknown function DUF402 AFR_36340 f04da9fe9f9b506d5a5e99ba052330e2 216 Gene3D G3DSA:2.40.380.10 1 198 5.5E-62 T 12-10-2018 IPR035930 FomD-like superfamily AFR_36340 f04da9fe9f9b506d5a5e99ba052330e2 216 SUPERFAMILY SSF159234 60 199 1.31E-22 T 12-10-2018 IPR035930 FomD-like superfamily AFR_21205 5df053c09655810bd1a3194edfee1c56 293 PRINTS PR00095 Anthranilate synthase component I signature 129 142 6.7E-13 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_21205 5df053c09655810bd1a3194edfee1c56 293 PRINTS PR00095 Anthranilate synthase component I signature 237 251 6.7E-13 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_21205 5df053c09655810bd1a3194edfee1c56 293 PRINTS PR00095 Anthranilate synthase component I signature 223 237 6.7E-13 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_21205 5df053c09655810bd1a3194edfee1c56 293 PRINTS PR00095 Anthranilate synthase component I signature 143 156 6.7E-13 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFR_21205 5df053c09655810bd1a3194edfee1c56 293 Pfam PF00425 chorismate binding enzyme 34 280 1.1E-65 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFR_21205 5df053c09655810bd1a3194edfee1c56 293 Gene3D G3DSA:3.60.120.10 13 290 5.9E-84 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFR_21205 5df053c09655810bd1a3194edfee1c56 293 SUPERFAMILY SSF56322 22 288 8.77E-80 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFR_17670 33ec8578eba9eaf40931f6a32c1cc310 855 Gene3D G3DSA:3.40.50.1460 234 485 5.8E-40 T 12-10-2018 AFR_17670 33ec8578eba9eaf40931f6a32c1cc310 855 Pfam PF00656 Caspase domain 238 477 9.6E-15 T 12-10-2018 AFR_42730 915f9442097a7915e8f5dbd220edb357 161 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 141 6.3E-31 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_42730 915f9442097a7915e8f5dbd220edb357 161 SMART SM00852 5 148 7.5E-23 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_42730 915f9442097a7915e8f5dbd220edb357 161 Gene3D G3DSA:3.40.980.10 1 160 9.0E-49 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_42730 915f9442097a7915e8f5dbd220edb357 161 Pfam PF00994 Probable molybdopterin binding domain 6 146 3.8E-29 T 12-10-2018 IPR001453 MoaB/Mog domain AFR_42730 915f9442097a7915e8f5dbd220edb357 161 SUPERFAMILY SSF53218 2 153 3.01E-40 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFR_11195 06492803aaac9c1571fed0982f2386d1 299 SUPERFAMILY SSF161098 30 299 3.92E-70 T 12-10-2018 IPR035906 MetI-like superfamily AFR_11195 06492803aaac9c1571fed0982f2386d1 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 288 2.6E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_11195 06492803aaac9c1571fed0982f2386d1 299 Gene3D G3DSA:1.10.3720.10 26 289 3.2E-62 T 12-10-2018 IPR035906 MetI-like superfamily AFR_07185 6aeb94feca8dab8c08479e7704b81c76 148 SMART SM00347 31 132 2.4E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_07185 6aeb94feca8dab8c08479e7704b81c76 148 SUPERFAMILY SSF46785 10 143 1.18E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_07185 6aeb94feca8dab8c08479e7704b81c76 148 Gene3D G3DSA:1.10.10.10 2 145 8.8E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_07185 6aeb94feca8dab8c08479e7704b81c76 148 Pfam PF01047 MarR family 46 96 2.6E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFR_06910 57d611a92d04aaa96e141825f464cdbb 280 SUPERFAMILY SSF51679 3 279 7.85E-46 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_06910 57d611a92d04aaa96e141825f464cdbb 280 Gene3D G3DSA:3.20.20.30 2 279 7.7E-52 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_06910 57d611a92d04aaa96e141825f464cdbb 280 Pfam PF00296 Luciferase-like monooxygenase 13 215 4.4E-35 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_13660 84243ef4c7cfc5f41f017c24f92267cf 133 Pfam PF14079 Domain of unknown function (DUF4260) 16 125 1.9E-40 T 12-10-2018 IPR025356 Protein of unknown function DUF4260 AFR_02985 d80977c389641b80567f7b43b566f760 548 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 254 519 4.7E-74 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFR_02985 d80977c389641b80567f7b43b566f760 548 Pfam PF00391 PEP-utilising enzyme, mobile domain 160 228 2.0E-18 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFR_02985 d80977c389641b80567f7b43b566f760 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 444 459 6.0E-17 T 12-10-2018 AFR_02985 d80977c389641b80567f7b43b566f760 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 480 492 6.0E-17 T 12-10-2018 AFR_02985 d80977c389641b80567f7b43b566f760 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 427 442 6.0E-17 T 12-10-2018 AFR_02985 d80977c389641b80567f7b43b566f760 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 283 302 6.0E-17 T 12-10-2018 AFR_02985 d80977c389641b80567f7b43b566f760 548 Gene3D G3DSA:3.20.20.60 243 548 2.3E-91 T 12-10-2018 AFR_02985 d80977c389641b80567f7b43b566f760 548 Gene3D G3DSA:1.10.274.10 32 150 1.1E-42 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFR_02985 d80977c389641b80567f7b43b566f760 548 Pfam PF05524 PEP-utilising enzyme, N-terminal 14 130 2.5E-15 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AFR_02985 d80977c389641b80567f7b43b566f760 548 SUPERFAMILY SSF51621 252 529 3.14E-83 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFR_02985 d80977c389641b80567f7b43b566f760 548 SUPERFAMILY SSF47831 37 147 5.75E-16 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFR_02985 d80977c389641b80567f7b43b566f760 548 SUPERFAMILY SSF52009 130 236 6.93E-26 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFR_02985 d80977c389641b80567f7b43b566f760 548 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 427 445 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFR_02985 d80977c389641b80567f7b43b566f760 548 Gene3D G3DSA:3.50.30.10 15 232 1.1E-42 T 12-10-2018 AFR_18965 512fc07953293a8dd9ae3f8e495e56df 165 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 20 113 1.3E-14 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFR_18965 512fc07953293a8dd9ae3f8e495e56df 165 Gene3D G3DSA:3.40.140.10 15 137 4.2E-28 T 12-10-2018 AFR_18965 512fc07953293a8dd9ae3f8e495e56df 165 SUPERFAMILY SSF53927 19 116 7.53E-26 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFR_01020 de5b8c6556b19cb19637f13359ebd68f 241 Pfam PF01261 Xylose isomerase-like TIM barrel 25 199 3.8E-14 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_01020 de5b8c6556b19cb19637f13359ebd68f 241 SUPERFAMILY SSF51658 5 238 2.64E-28 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_01020 de5b8c6556b19cb19637f13359ebd68f 241 Gene3D G3DSA:3.20.20.150 1 238 1.9E-48 T 12-10-2018 AFR_05015 1e21793271c1b06749dbcf24d4ee6a41 536 Pfam PF04024 PspC domain 74 129 9.2E-12 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal AFR_05015 1e21793271c1b06749dbcf24d4ee6a41 536 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 427 534 4.0E-7 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF AFR_40785 751c098b81f6925600ade46dfdc0979a 261 SUPERFAMILY SSF55811 13 222 6.78E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFR_40785 751c098b81f6925600ade46dfdc0979a 261 Pfam PF00293 NUDIX domain 26 209 1.6E-6 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFR_40785 751c098b81f6925600ade46dfdc0979a 261 Gene3D G3DSA:3.90.79.10 20 248 1.1E-54 T 12-10-2018 AFR_16105 2a8aabefbbe8ccfb45bca97d413baa15 189 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 26 149 4.4E-17 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_16105 2a8aabefbbe8ccfb45bca97d413baa15 189 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 18 126 8.4E-7 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_16105 2a8aabefbbe8ccfb45bca97d413baa15 189 SUPERFAMILY SSF109854 10 134 9.61E-12 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_16105 2a8aabefbbe8ccfb45bca97d413baa15 189 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 27 183 2.1E-25 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 AFR_07460 04e5c10242d1572ed3afbfae49f4e524 186 SUPERFAMILY SSF52980 13 161 1.45E-18 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFR_07460 04e5c10242d1572ed3afbfae49f4e524 186 Gene3D G3DSA:3.90.1570.10 12 173 3.5E-13 T 12-10-2018 AFR_07460 04e5c10242d1572ed3afbfae49f4e524 186 Pfam PF05685 Putative restriction endonuclease 23 177 7.7E-23 T 12-10-2018 IPR008538 Domain of unknown function DUF820 AFR_13730 28ec322d1d8bc971bb4727b0839c73f9 164 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 40 155 5.9E-10 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_13730 28ec322d1d8bc971bb4727b0839c73f9 164 Gene3D G3DSA:3.30.530.20 30 159 4.7E-14 T 12-10-2018 IPR023393 START-like domain superfamily AFR_13730 28ec322d1d8bc971bb4727b0839c73f9 164 SUPERFAMILY SSF55961 37 131 1.48E-9 T 12-10-2018 AFR_07520 13e75eaa1e25dc454021a97f793d46d6 126 Pfam PF06305 Lipopolysaccharide assembly protein A domain 75 125 9.0E-9 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 AFR_01860 6dbe86b4716bd43980da8c2e5caa11ca 63 Pfam PF14029 Protein of unknown function (DUF4244) 15 63 1.2E-25 T 12-10-2018 IPR025338 Protein of unknown function DUF4244 AFR_27990 2f956316331d5380e3ef7b4080d7198d 457 ProSitePatterns PS00455 Putative AMP-binding domain signature. 132 143 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFR_27990 2f956316331d5380e3ef7b4080d7198d 457 Gene3D G3DSA:3.40.50.12780 6 361 2.9E-100 T 12-10-2018 AFR_27990 2f956316331d5380e3ef7b4080d7198d 457 Pfam PF00501 AMP-binding enzyme 16 367 5.2E-70 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFR_27990 2f956316331d5380e3ef7b4080d7198d 457 Pfam PF13193 AMP-binding enzyme C-terminal domain 377 449 6.8E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFR_27990 2f956316331d5380e3ef7b4080d7198d 457 Gene3D G3DSA:3.30.300.310 364 457 5.4E-29 T 12-10-2018 AFR_27990 2f956316331d5380e3ef7b4080d7198d 457 SUPERFAMILY SSF56801 14 456 6.67E-114 T 12-10-2018 AFR_37250 bfa1245135f60b9bc6c2c7c2955ac806 215 Pfam PF00005 ABC transporter 23 160 1.8E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_37250 bfa1245135f60b9bc6c2c7c2955ac806 215 Gene3D G3DSA:3.40.50.300 4 212 2.0E-47 T 12-10-2018 AFR_37250 bfa1245135f60b9bc6c2c7c2955ac806 215 SUPERFAMILY SSF52540 5 200 6.61E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_37250 bfa1245135f60b9bc6c2c7c2955ac806 215 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_37250 bfa1245135f60b9bc6c2c7c2955ac806 215 SMART SM00382 30 210 5.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_32865 192c79cfb5e28909fd23bbf29a944274 353 Gene3D G3DSA:3.40.50.300 10 161 1.9E-19 T 12-10-2018 AFR_32865 192c79cfb5e28909fd23bbf29a944274 353 SMART SM00382 21 156 2.3E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_32865 192c79cfb5e28909fd23bbf29a944274 353 Pfam PF07728 AAA domain (dynein-related subfamily) 25 117 6.7E-10 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFR_32865 192c79cfb5e28909fd23bbf29a944274 353 SUPERFAMILY SSF52540 22 157 1.46E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_34235 c609dc7e6f74b46d02efbb44e5af5b9c 414 Pfam PF12671 Putative amidase domain 240 392 4.2E-10 T 12-10-2018 IPR024301 Putative amidase domain AFR_23740 2bcddc0e3db1c6b9bdeda9b2bab87c45 121 Gene3D G3DSA:3.10.180.10 1 120 6.0E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_23740 2bcddc0e3db1c6b9bdeda9b2bab87c45 121 SUPERFAMILY SSF54593 3 113 8.59E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_16575 bdf23cc6a6126ede868a6960d4fac824 310 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 150 260 3.3E-27 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 AFR_16575 bdf23cc6a6126ede868a6960d4fac824 310 Gene3D G3DSA:3.40.50.2000 142 307 3.7E-40 T 12-10-2018 AFR_16575 bdf23cc6a6126ede868a6960d4fac824 310 SUPERFAMILY SSF53756 2 303 1.15E-52 T 12-10-2018 AFR_21825 46facd3bfd556b23a4843fb3c8412d89 458 Gene3D G3DSA:3.20.20.70 85 398 3.1E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_21825 46facd3bfd556b23a4843fb3c8412d89 458 SUPERFAMILY SSF102114 149 413 1.61E-12 T 12-10-2018 AFR_17225 bf438ad7e06277d188bac6985089dfa5 146 SUPERFAMILY SSF52172 8 138 1.85E-31 T 12-10-2018 IPR011006 CheY-like superfamily AFR_17225 bf438ad7e06277d188bac6985089dfa5 146 Pfam PF00072 Response regulator receiver domain 11 127 4.9E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17225 bf438ad7e06277d188bac6985089dfa5 146 SMART SM00448 9 131 3.4E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_17225 bf438ad7e06277d188bac6985089dfa5 146 Gene3D G3DSA:3.40.50.2300 2 142 1.2E-34 T 12-10-2018 AFR_02990 6c2285579b7103c63178d278083402db 311 Pfam PF07070 SpoOM protein 3 218 8.9E-81 T 12-10-2018 IPR009776 Sporulation stage 0, protein M AFR_14045 26350f36bb79b990ea95207dc2868b6d 386 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 53 375 1.0E-63 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 AFR_14045 26350f36bb79b990ea95207dc2868b6d 386 SUPERFAMILY SSF54909 48 380 1.97E-73 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_14045 26350f36bb79b990ea95207dc2868b6d 386 Pfam PF04261 Dyp-type peroxidase family 53 375 9.2E-71 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 AFR_25565 195bda8e72392ef0205beacafa2c0c12 136 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 13 128 2.1E-28 T 12-10-2018 IPR019920 F420-binding domain, putative AFR_25565 195bda8e72392ef0205beacafa2c0c12 136 SUPERFAMILY SSF50475 10 128 5.89E-32 T 12-10-2018 AFR_25565 195bda8e72392ef0205beacafa2c0c12 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 94 1.9E-9 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_25565 195bda8e72392ef0205beacafa2c0c12 136 Gene3D G3DSA:2.30.110.10 3 133 9.2E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_01240 6c0a01675068e6c7e57500c8200db625 178 SUPERFAMILY SSF46785 3 166 4.7E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_01240 6c0a01675068e6c7e57500c8200db625 178 Gene3D G3DSA:1.10.10.10 1 87 4.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_01240 6c0a01675068e6c7e57500c8200db625 178 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 4.3E-17 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_03920 6a2ba502f895f722d01b3bfbb291d9bc 410 Gene3D G3DSA:3.90.550.10 7 253 2.8E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_03920 6a2ba502f895f722d01b3bfbb291d9bc 410 Pfam PF04138 GtrA-like protein 284 401 1.0E-13 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 AFR_03920 6a2ba502f895f722d01b3bfbb291d9bc 410 Pfam PF00535 Glycosyl transferase family 2 22 189 5.8E-21 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_03920 6a2ba502f895f722d01b3bfbb291d9bc 410 SUPERFAMILY SSF53448 19 231 2.63E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_16850 f497de04f13ef2396aedeca5f9b48a8c 328 Gene3D G3DSA:1.10.3720.10 84 320 5.5E-54 T 12-10-2018 IPR035906 MetI-like superfamily AFR_16850 f497de04f13ef2396aedeca5f9b48a8c 328 SUPERFAMILY SSF161098 39 318 4.97E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_16850 f497de04f13ef2396aedeca5f9b48a8c 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 311 9.1E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30800 e137963794ff9a4b0b560127edec4f02 265 Gene3D G3DSA:3.40.50.720 1 261 4.0E-52 T 12-10-2018 AFR_30800 e137963794ff9a4b0b560127edec4f02 265 Pfam PF04321 RmlD substrate binding domain 1 256 2.2E-36 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFR_30800 e137963794ff9a4b0b560127edec4f02 265 SUPERFAMILY SSF51735 1 262 2.03E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_32820 ffe515519d535dea17eb2ab7eb5f22bf 274 Gene3D G3DSA:3.40.50.1820 1 272 3.2E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_32820 ffe515519d535dea17eb2ab7eb5f22bf 274 PIRSF PIRSF037442 2 273 9.0E-43 T 12-10-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 AFR_32820 ffe515519d535dea17eb2ab7eb5f22bf 274 Pfam PF12697 Alpha/beta hydrolase family 26 262 3.5E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_32820 ffe515519d535dea17eb2ab7eb5f22bf 274 SUPERFAMILY SSF53474 2 270 2.75E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16390 ec83fcfd51176542e7af1f2188bed457 403 Pfam PF07690 Major Facilitator Superfamily 53 238 2.1E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_16390 ec83fcfd51176542e7af1f2188bed457 403 Gene3D G3DSA:1.20.1250.20 17 400 8.4E-29 T 12-10-2018 AFR_16390 ec83fcfd51176542e7af1f2188bed457 403 SUPERFAMILY SSF103473 19 395 1.96E-29 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_35345 f80c1c18b3ee1b85975584237874ed69 72 Pfam PF11238 Protein of unknown function (DUF3039) 15 70 1.6E-27 T 12-10-2018 IPR021400 Protein of unknown function DUF3039 AFR_29330 5d8aa2353001ade65b4cb084b924da18 410 Pfam PF07690 Major Facilitator Superfamily 22 357 5.7E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_29330 5d8aa2353001ade65b4cb084b924da18 410 Gene3D G3DSA:1.20.1250.20 13 200 2.4E-8 T 12-10-2018 AFR_29330 5d8aa2353001ade65b4cb084b924da18 410 SUPERFAMILY SSF103473 5 396 2.49E-40 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_29330 5d8aa2353001ade65b4cb084b924da18 410 Gene3D G3DSA:1.20.1250.20 208 399 4.1E-17 T 12-10-2018 AFR_10060 b71114691e667b051ac4d50926ec4a37 503 Gene3D G3DSA:1.20.1530.20 7 391 1.5E-20 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFR_10060 b71114691e667b051ac4d50926ec4a37 503 SUPERFAMILY SSF116726 412 480 2.75E-11 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_10060 b71114691e667b051ac4d50926ec4a37 503 Pfam PF02080 TrkA-C domain 416 480 7.7E-12 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFR_10060 b71114691e667b051ac4d50926ec4a37 503 Gene3D G3DSA:3.30.70.1450 402 481 2.3E-13 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFR_10060 b71114691e667b051ac4d50926ec4a37 503 Pfam PF00999 Sodium/hydrogen exchanger family 15 388 8.4E-49 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_32625 060d9ad635d6798847366fbb8f21a3e2 151 Gene3D G3DSA:1.10.10.10 1 140 1.2E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_32625 060d9ad635d6798847366fbb8f21a3e2 151 Pfam PF02082 Transcriptional regulator 2 82 7.4E-24 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFR_32625 060d9ad635d6798847366fbb8f21a3e2 151 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 130 1.8E-31 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFR_32625 060d9ad635d6798847366fbb8f21a3e2 151 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site AFR_32625 060d9ad635d6798847366fbb8f21a3e2 151 SUPERFAMILY SSF46785 3 132 3.27E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_38385 2a535e0124ad8917a411b0b8d0111840 293 SUPERFAMILY SSF51197 11 229 2.97E-34 T 12-10-2018 AFR_38385 2a535e0124ad8917a411b0b8d0111840 293 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 20 215 6.4E-15 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase AFR_38385 2a535e0124ad8917a411b0b8d0111840 293 Gene3D G3DSA:2.60.120.620 3 239 2.2E-38 T 12-10-2018 AFR_00545 0f3d5045c5966fe4f82eaa743d360964 401 Gene3D G3DSA:1.20.1530.20 4 380 1.5E-55 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFR_00545 0f3d5045c5966fe4f82eaa743d360964 401 Pfam PF00999 Sodium/hydrogen exchanger family 14 371 3.2E-50 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_00985 63eb2e3d119cd4d131959d2fb79a9c10 107 Pfam PF12277 Protein of unknown function (DUF3618) 8 52 5.8E-17 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 AFR_29925 c7567bfac162d42848ba941ab5e621fd 392 Pfam PF12555 Thiamine pyrophosphokinase C terminal 334 385 3.5E-15 T 12-10-2018 IPR022215 Thiamine pyrophosphokinase C-terminal AFR_29925 c7567bfac162d42848ba941ab5e621fd 392 SUPERFAMILY SSF63999 174 338 6.67E-29 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFR_29925 c7567bfac162d42848ba941ab5e621fd 392 Gene3D G3DSA:3.40.50.10240 176 257 3.0E-10 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFR_33710 d80abdce9f6d5c9805a2a4e39b1b6791 437 Gene3D G3DSA:1.20.1250.20 33 425 5.8E-11 T 12-10-2018 AFR_33710 d80abdce9f6d5c9805a2a4e39b1b6791 437 SUPERFAMILY SSF103473 34 423 1.7E-15 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_04110 86f0d12d126556b0a6d318b4269e94ca 74 Pfam PF11305 Protein of unknown function (DUF3107) 1 71 1.6E-27 T 12-10-2018 IPR021456 Protein of unknown function DUF3107 AFR_30570 9ea10cdf9fd6e73b49146d5b5939f1a2 834 Gene3D G3DSA:1.10.8.630 20 132 6.5E-15 T 12-10-2018 AFR_30570 9ea10cdf9fd6e73b49146d5b5939f1a2 834 Gene3D G3DSA:3.40.50.300 351 502 1.0E-21 T 12-10-2018 AFR_30570 9ea10cdf9fd6e73b49146d5b5939f1a2 834 Hamap MF_00983 Probable primosomal protein N' [priA]. 27 833 20.303 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AFR_07695 9f4d78c08cf0f78f03eff84acc25b5e5 151 Gene3D G3DSA:3.40.630.30 2 149 2.7E-34 T 12-10-2018 AFR_07695 9f4d78c08cf0f78f03eff84acc25b5e5 151 Pfam PF00583 Acetyltransferase (GNAT) family 43 123 5.5E-11 T 12-10-2018 IPR000182 GNAT domain AFR_07695 9f4d78c08cf0f78f03eff84acc25b5e5 151 SUPERFAMILY SSF55729 36 136 4.46E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_21775 c7724c6fb350f9402873f3bdeec350b3 112 Gene3D G3DSA:2.20.28.270 1 80 1.2E-34 T 12-10-2018 IPR038638 RbpA superfamily AFR_21775 c7724c6fb350f9402873f3bdeec350b3 112 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 112 25.006 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 AFR_21775 c7724c6fb350f9402873f3bdeec350b3 112 Pfam PF13397 RNA polymerase-binding protein 4 107 4.1E-42 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 AFR_06515 9370c89d4c7a49b2e5d7981f020515b5 470 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 59 113 3.3E-5 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFR_06515 9370c89d4c7a49b2e5d7981f020515b5 470 SUPERFAMILY SSF56349 351 431 3.94E-9 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_06515 9370c89d4c7a49b2e5d7981f020515b5 470 SUPERFAMILY SSF56349 58 309 1.73E-19 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFR_06515 9370c89d4c7a49b2e5d7981f020515b5 470 Gene3D G3DSA:1.10.150.130 55 156 9.4E-17 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFR_27435 2caf4719493f853fcd827e65ea2388b1 366 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 42 353 1.1E-47 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFR_27435 2caf4719493f853fcd827e65ea2388b1 366 Gene3D G3DSA:3.20.20.190 35 358 2.7E-105 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_27435 2caf4719493f853fcd827e65ea2388b1 366 SUPERFAMILY SSF51695 38 354 1.05E-70 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_28595 3aea3ef729107b2da88c1a1a58bf58e9 389 Pfam PF12704 MacB-like periplasmic core domain 27 230 1.6E-14 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFR_28595 3aea3ef729107b2da88c1a1a58bf58e9 389 Pfam PF02687 FtsX-like permease family 294 382 4.4E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_05775 42969db216d07e0726f5278fed3a235b 608 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 337 559 8.6E-12 T 12-10-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal AFR_05775 42969db216d07e0726f5278fed3a235b 608 SUPERFAMILY SSF50969 356 589 1.73E-8 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFR_39780 836b1e9e8b4ef3e1d03ed5f9d44e09d9 155 Pfam PF14325 Domain of unknown function (DUF4383) 15 131 5.5E-11 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 AFR_23485 59dc57099b2ec9f95f2fafd2dddec103 211 Pfam PF13649 Methyltransferase domain 62 99 7.2E-7 T 12-10-2018 AFR_23485 59dc57099b2ec9f95f2fafd2dddec103 211 SUPERFAMILY SSF53335 60 178 4.67E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_23485 59dc57099b2ec9f95f2fafd2dddec103 211 Gene3D G3DSA:3.40.50.150 34 211 1.5E-14 T 12-10-2018 AFR_26440 5ca8503d71f0027dfabb7e11b43a774c 387 Pfam PF13398 Peptidase M50B-like 72 156 1.0E-5 T 12-10-2018 AFR_26440 5ca8503d71f0027dfabb7e11b43a774c 387 PIRSF PIRSF006404 15 384 5.8E-74 T 12-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS AFR_27745 b612dfb8fe6c2922ea9a47990ce09060 278 Pfam PF04954 Siderophore-interacting protein 135 252 1.9E-40 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain AFR_27745 b612dfb8fe6c2922ea9a47990ce09060 278 Pfam PF08021 Siderophore-interacting FAD-binding domain 13 127 6.9E-35 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting AFR_27745 b612dfb8fe6c2922ea9a47990ce09060 278 Gene3D G3DSA:3.40.50.80 131 274 2.4E-52 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFR_27745 b612dfb8fe6c2922ea9a47990ce09060 278 SUPERFAMILY SSF63380 10 134 2.46E-11 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFR_27745 b612dfb8fe6c2922ea9a47990ce09060 278 Gene3D G3DSA:2.40.30.10 2 128 1.3E-35 T 12-10-2018 AFR_14380 760bb39b6c4dfc8cdd8ceeef4796c146 191 SUPERFAMILY SSF160904 6 184 9.55E-35 T 12-10-2018 AFR_14380 760bb39b6c4dfc8cdd8ceeef4796c146 191 Gene3D G3DSA:1.10.3300.10 4 186 5.4E-21 T 12-10-2018 IPR023286 ABATE domain superfamily AFR_14380 760bb39b6c4dfc8cdd8ceeef4796c146 191 Pfam PF11706 CGNR zinc finger 146 185 1.4E-11 T 12-10-2018 IPR021005 Zinc finger, CGNR AFR_14380 760bb39b6c4dfc8cdd8ceeef4796c146 191 Pfam PF07336 Putative stress-induced transcription regulator 7 142 7.1E-17 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator AFR_08225 ba8cc6bc24c77d5751fee859818c5088 366 SUPERFAMILY SSF51658 40 231 6.13E-12 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_08225 ba8cc6bc24c77d5751fee859818c5088 366 Gene3D G3DSA:3.20.20.150 32 260 4.6E-13 T 12-10-2018 AFR_08225 ba8cc6bc24c77d5751fee859818c5088 366 Pfam PF01261 Xylose isomerase-like TIM barrel 49 232 7.1E-7 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_02370 ed4d8e5e66d2e0e0d2fbed6bd6abdc7a 234 Pfam PF13490 Putative zinc-finger 11 35 3.0E-6 T 12-10-2018 IPR027383 Putative zinc-finger AFR_02370 ed4d8e5e66d2e0e0d2fbed6bd6abdc7a 234 Gene3D G3DSA:1.10.10.1320 4 59 7.9E-10 T 12-10-2018 AFR_10620 dda8e7c07bc67aae0f26578585d54412 342 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 56 298 6.1E-76 T 12-10-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA AFR_06695 de7804bb32acf59ae34091289eee51cd 427 Gene3D G3DSA:2.130.10.10 237 427 2.1E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_06695 de7804bb32acf59ae34091289eee51cd 427 SUPERFAMILY SSF50939 113 421 5.3E-16 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 AFR_06695 de7804bb32acf59ae34091289eee51cd 427 Gene3D G3DSA:2.120.10.10 75 215 1.6E-7 T 12-10-2018 AFR_15865 67630638425c85460788e86e39c2105a 515 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 444 1.4E-148 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane AFR_34465 7dd32dcd592b1cc651d520224080332e 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 9.9E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34465 7dd32dcd592b1cc651d520224080332e 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 9.9E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34465 7dd32dcd592b1cc651d520224080332e 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 9.9E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34465 7dd32dcd592b1cc651d520224080332e 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 9.9E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34465 7dd32dcd592b1cc651d520224080332e 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 9.9E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34465 7dd32dcd592b1cc651d520224080332e 295 Gene3D G3DSA:3.40.50.720 12 295 4.2E-75 T 12-10-2018 AFR_34465 7dd32dcd592b1cc651d520224080332e 295 Pfam PF00106 short chain dehydrogenase 23 215 4.7E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_34465 7dd32dcd592b1cc651d520224080332e 295 SUPERFAMILY SSF51735 19 262 1.54E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12720 1b213b06245d049440d3e91ca2043aac 321 SUPERFAMILY SSF51735 132 248 8.01E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12720 1b213b06245d049440d3e91ca2043aac 321 Pfam PF13602 Zinc-binding dehydrogenase 202 319 6.2E-12 T 12-10-2018 AFR_12720 1b213b06245d049440d3e91ca2043aac 321 Gene3D G3DSA:3.40.50.720 143 270 8.7E-64 T 12-10-2018 AFR_12720 1b213b06245d049440d3e91ca2043aac 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.5E-10 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFR_12720 1b213b06245d049440d3e91ca2043aac 321 SUPERFAMILY SSF50129 1 168 1.0E-32 T 12-10-2018 IPR011032 GroES-like superfamily AFR_12720 1b213b06245d049440d3e91ca2043aac 321 Gene3D G3DSA:3.90.180.10 9 318 8.7E-64 T 12-10-2018 AFR_12720 1b213b06245d049440d3e91ca2043aac 321 SMART SM00829 10 319 3.4E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFR_04235 9c092e65d4b8b304053b41f10bb4c521 319 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 319 22.457 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04235 9c092e65d4b8b304053b41f10bb4c521 319 Pfam PF00146 NADH dehydrogenase 11 313 5.5E-102 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_17375 f1716016e64036e89829da9fa0306db9 431 Pfam PF01757 Acyltransferase family 13 382 1.1E-30 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_35315 52458c05e9d5f1c680547e66b0bdb244 178 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 58 145 6.9E-11 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain AFR_03330 41e53754e88172f60a8a685b73d8742c 550 Pfam PF00999 Sodium/hydrogen exchanger family 9 418 6.0E-54 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_03330 41e53754e88172f60a8a685b73d8742c 550 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 10 545 6.2E-97 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 AFR_18825 2330775494ef3cca0bf5173d06e35e6b 251 Gene3D G3DSA:3.20.20.80 2 246 2.8E-64 T 12-10-2018 AFR_18825 2330775494ef3cca0bf5173d06e35e6b 251 Pfam PF02156 Glycosyl hydrolase family 26 57 183 7.2E-18 T 12-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 AFR_18825 2330775494ef3cca0bf5173d06e35e6b 251 SUPERFAMILY SSF51445 7 242 3.16E-46 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_38630 4f48c3529236b0ab761098b7e486587a 244 SUPERFAMILY SSF51735 1 242 2.52E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_38630 4f48c3529236b0ab761098b7e486587a 244 Gene3D G3DSA:3.40.50.720 1 244 1.5E-40 T 12-10-2018 AFR_38630 4f48c3529236b0ab761098b7e486587a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38630 4f48c3529236b0ab761098b7e486587a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38630 4f48c3529236b0ab761098b7e486587a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38630 4f48c3529236b0ab761098b7e486587a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38630 4f48c3529236b0ab761098b7e486587a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_38630 4f48c3529236b0ab761098b7e486587a 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 240 1.2E-34 T 12-10-2018 AFR_14660 a541a0549e27407fb2e28f5ce21610e5 351 Gene3D G3DSA:2.60.20.10 253 349 5.0E-5 T 12-10-2018 AFR_12670 5aea6d2861dc693696e199bfa78e330a 194 Gene3D G3DSA:1.10.3210.10 7 97 1.6E-9 T 12-10-2018 AFR_12670 5aea6d2861dc693696e199bfa78e330a 194 Pfam PF01966 HD domain 26 64 2.7E-5 T 12-10-2018 IPR006674 HD domain AFR_12670 5aea6d2861dc693696e199bfa78e330a 194 SUPERFAMILY SSF109604 23 100 1.06E-15 T 12-10-2018 AFR_12670 5aea6d2861dc693696e199bfa78e330a 194 TIGRFAM TIGR00277 HDIG: HDIG domain 27 98 3.4E-7 T 12-10-2018 IPR006675 HDIG domain AFR_33390 65d4aa5cb17a5a7a6914d8ca01b6a2e0 228 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_33390 65d4aa5cb17a5a7a6914d8ca01b6a2e0 228 Gene3D G3DSA:3.40.50.300 3 227 9.8E-65 T 12-10-2018 AFR_33390 65d4aa5cb17a5a7a6914d8ca01b6a2e0 228 SUPERFAMILY SSF52540 5 222 9.65E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_33390 65d4aa5cb17a5a7a6914d8ca01b6a2e0 228 SMART SM00382 30 218 2.8E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_33390 65d4aa5cb17a5a7a6914d8ca01b6a2e0 228 Pfam PF00005 ABC transporter 22 169 8.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_13115 919f9d96b66f643e745984ca18f59797 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 1.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_13115 919f9d96b66f643e745984ca18f59797 211 SUPERFAMILY SSF46689 19 91 8.72E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_13115 919f9d96b66f643e745984ca18f59797 211 Gene3D G3DSA:1.10.357.10 26 207 4.0E-29 T 12-10-2018 AFR_13115 919f9d96b66f643e745984ca18f59797 211 SUPERFAMILY SSF48498 102 204 5.01E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_07280 b1527c46daedf38a145b47cca1dfbf5a 240 Gene3D G3DSA:2.40.50.140 2 117 1.6E-35 T 12-10-2018 AFR_07280 b1527c46daedf38a145b47cca1dfbf5a 240 SUPERFAMILY SSF50249 5 153 1.62E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFR_07280 b1527c46daedf38a145b47cca1dfbf5a 240 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 106 4.5E-16 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFR_07280 b1527c46daedf38a145b47cca1dfbf5a 240 Pfam PF00436 Single-strand binding protein family 5 106 3.2E-17 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFR_35530 0c0e7d71b2fd9e2708aec102e6cc360e 704 SUPERFAMILY SSF75011 53 317 4.18E-8 T 12-10-2018 AFR_01840 d919c5c9bb1d84559f975a1102074f8e 349 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 1 339 2.7E-115 T 12-10-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like AFR_01840 d919c5c9bb1d84559f975a1102074f8e 349 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 113 243 5.8E-6 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFR_01840 d919c5c9bb1d84559f975a1102074f8e 349 Gene3D G3DSA:3.40.50.300 110 345 6.9E-27 T 12-10-2018 AFR_01840 d919c5c9bb1d84559f975a1102074f8e 349 SUPERFAMILY SSF52540 110 335 2.88E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_03175 b6287be568a968deba9f16d6949f4436 520 Pfam PF00999 Sodium/hydrogen exchanger family 10 440 2.2E-47 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFR_36135 b7c9d44aa0f2a89eccaaac55b96629ad 192 Gene3D G3DSA:1.10.10.10 48 148 6.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_36135 b7c9d44aa0f2a89eccaaac55b96629ad 192 SUPERFAMILY SSF46785 53 141 6.57E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_36135 b7c9d44aa0f2a89eccaaac55b96629ad 192 Pfam PF03551 Transcriptional regulator PadR-like family 57 125 2.0E-21 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFR_36410 d3a366380ec9933cfc5f31aebae6d50c 296 Pfam PF05675 Protein of unknown function (DUF817) 3 235 3.9E-99 T 12-10-2018 IPR008535 Protein of unknown function DUF817 AFR_36410 d3a366380ec9933cfc5f31aebae6d50c 296 PIRSF PIRSF009141 1 252 5.6E-100 T 12-10-2018 IPR008535 Protein of unknown function DUF817 AFR_40395 9bfd98f45750bec20701e93f43756b04 161 SUPERFAMILY SSF140566 4 127 1.44E-7 T 12-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 AFR_40395 9bfd98f45750bec20701e93f43756b04 161 Pfam PF05130 FlgN protein 3 146 1.4E-16 T 12-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 AFR_23165 7e90e0d671b6582f71b807bf9066c697 233 Gene3D G3DSA:3.10.180.10 3 121 3.4E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_23165 7e90e0d671b6582f71b807bf9066c697 233 Gene3D G3DSA:3.10.180.10 127 233 7.1E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_23165 7e90e0d671b6582f71b807bf9066c697 233 SUPERFAMILY SSF54593 18 118 1.88E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_23165 7e90e0d671b6582f71b807bf9066c697 233 SUPERFAMILY SSF54593 141 232 2.31E-8 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_15925 5d4bf18aa6a408aa1a9544970af2a650 349 Gene3D G3DSA:2.120.10.30 196 346 4.0E-14 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_15925 5d4bf18aa6a408aa1a9544970af2a650 349 SUPERFAMILY SSF82171 118 336 3.02E-12 T 12-10-2018 AFR_26465 ce7ec4cf1abc2c0f424f23a25da93793 255 Pfam PF00005 ABC transporter 31 177 5.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_26465 ce7ec4cf1abc2c0f424f23a25da93793 255 SMART SM00382 40 226 3.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_26465 ce7ec4cf1abc2c0f424f23a25da93793 255 SUPERFAMILY SSF52540 14 230 1.17E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_26465 ce7ec4cf1abc2c0f424f23a25da93793 255 Gene3D G3DSA:3.40.50.300 13 252 3.2E-67 T 12-10-2018 AFR_31025 9f9382accac4f1ad4ac9261e10484a37 287 SUPERFAMILY SSF50891 104 270 4.68E-25 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_31025 9f9382accac4f1ad4ac9261e10484a37 287 Gene3D G3DSA:2.40.100.10 102 273 7.0E-28 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFR_31025 9f9382accac4f1ad4ac9261e10484a37 287 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 103 268 2.3E-18 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFR_37320 b14758d96f46bc6ba39363b649c35a18 155 Pfam PF10739 Protein of unknown function (DUF2550) 11 137 2.2E-39 T 12-10-2018 IPR019675 Protein of unknown function DUF2550 AFR_27770 94c7c1baaa3ceedab80038327941977e 322 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 6 313 3.2E-14 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFR_27770 94c7c1baaa3ceedab80038327941977e 322 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 6 304 2.8E-33 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFR_20190 f5a57e825a89f16c02dfaa830c6e9a8e 160 SUPERFAMILY SSF160904 2 153 3.53E-31 T 12-10-2018 AFR_20190 f5a57e825a89f16c02dfaa830c6e9a8e 160 Pfam PF11706 CGNR zinc finger 111 153 1.9E-17 T 12-10-2018 IPR021005 Zinc finger, CGNR AFR_20190 f5a57e825a89f16c02dfaa830c6e9a8e 160 Gene3D G3DSA:1.10.3300.10 12 154 1.3E-20 T 12-10-2018 IPR023286 ABATE domain superfamily AFR_04375 811396548ac264104eab823c5b4a3abb 323 Pfam PF07859 alpha/beta hydrolase fold 88 294 1.2E-48 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_04375 811396548ac264104eab823c5b4a3abb 323 Gene3D G3DSA:3.40.50.1820 7 322 1.8E-75 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_04375 811396548ac264104eab823c5b4a3abb 323 SUPERFAMILY SSF53474 67 320 1.17E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_16495 3499a747e93b5dafbee33010a3c0fcc5 417 Pfam PF07394 Protein of unknown function (DUF1501) 50 371 1.5E-30 T 12-10-2018 IPR010869 Protein of unknown function DUF1501 AFR_03925 a01e37c39e92fffc9aca0bcf248ead1c 701 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 97 251 9.6E-31 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFR_08670 e1f2cfce584d3366f20f5d0ce8a90870 536 SUPERFAMILY SSF51445 14 404 2.11E-80 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_08670 e1f2cfce584d3366f20f5d0ce8a90870 536 Gene3D G3DSA:3.20.20.300 13 397 7.8E-102 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFR_08670 e1f2cfce584d3366f20f5d0ce8a90870 536 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 60 376 3.5E-78 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFR_36880 718180c2bdb1b157113b958e653b44d4 346 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 1 307 1.8E-119 T 12-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 AFR_36880 718180c2bdb1b157113b958e653b44d4 346 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 1 309 1.6E-137 T 12-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 AFR_36880 718180c2bdb1b157113b958e653b44d4 346 Gene3D G3DSA:3.90.550.10 1 322 1.1E-144 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_24855 8d8fc9ff239aacaa6ee9e2190991215c 268 Pfam PF03883 Peroxide stress protein YaaA 2 250 3.4E-36 T 12-10-2018 IPR005583 Peroxide stress protein YaaA AFR_00600 5f2d2481feb0d4f12de346cb2730800a 277 Pfam PF09335 SNARE associated Golgi protein 54 189 2.0E-20 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_20720 531f482a90d0e1bf6f9ffcf36d1d84b2 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 327 3.6E-50 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_31170 b9188e6392a565f547abbe015835da8e 319 SUPERFAMILY SSF101478 28 305 7.19E-47 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFR_31170 b9188e6392a565f547abbe015835da8e 319 Gene3D G3DSA:1.10.4080.10 25 314 6.7E-54 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFR_31170 b9188e6392a565f547abbe015835da8e 319 Pfam PF03747 ADP-ribosylglycohydrolase 30 300 4.8E-45 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 AFR_12570 cc72d8f6651e66a85501cc26ed8ad560 255 Gene3D G3DSA:3.40.50.720 2 255 5.4E-46 T 12-10-2018 AFR_12570 cc72d8f6651e66a85501cc26ed8ad560 255 SUPERFAMILY SSF51735 3 213 1.75E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_12570 cc72d8f6651e66a85501cc26ed8ad560 255 Pfam PF00106 short chain dehydrogenase 3 118 9.4E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12570 cc72d8f6651e66a85501cc26ed8ad560 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12570 cc72d8f6651e66a85501cc26ed8ad560 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_12570 cc72d8f6651e66a85501cc26ed8ad560 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_21145 81e8ba3701f674187f6e3c9aae7ceb47 245 Pfam PF11350 Protein of unknown function (DUF3152) 47 207 1.0E-37 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 AFR_21145 81e8ba3701f674187f6e3c9aae7ceb47 245 SUPERFAMILY SSF55486 109 204 1.39E-12 T 12-10-2018 AFR_02095 6c2cdbf8289287c9b5d00cf1aaeb0edd 208 Gene3D G3DSA:1.10.150.240 17 77 3.2E-29 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFR_02095 6c2cdbf8289287c9b5d00cf1aaeb0edd 208 Gene3D G3DSA:3.40.50.1000 7 185 3.2E-29 T 12-10-2018 IPR023214 HAD superfamily AFR_02095 6c2cdbf8289287c9b5d00cf1aaeb0edd 208 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 158 4.2E-12 T 12-10-2018 AFR_02095 6c2cdbf8289287c9b5d00cf1aaeb0edd 208 SUPERFAMILY SSF56784 4 198 8.41E-37 T 12-10-2018 IPR036412 HAD-like superfamily AFR_20155 af30c8726f746354ed641bcf744afe09 305 Gene3D G3DSA:3.30.2010.10 100 189 5.5E-7 T 12-10-2018 AFR_20155 af30c8726f746354ed641bcf744afe09 305 Pfam PF01435 Peptidase family M48 127 188 6.2E-10 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFR_27130 26e5e17db46ba5ce2d5531e728b49ff0 117 SUPERFAMILY SSF142906 4 109 1.03E-16 T 12-10-2018 IPR038056 YjbR-like superfamily AFR_27130 26e5e17db46ba5ce2d5531e728b49ff0 117 Pfam PF04237 YjbR 10 104 1.6E-15 T 12-10-2018 IPR007351 Uncharacterised protein YjbR AFR_27130 26e5e17db46ba5ce2d5531e728b49ff0 117 Gene3D G3DSA:3.90.1150.30 1 116 6.3E-8 T 12-10-2018 IPR038056 YjbR-like superfamily AFR_21055 d97a81300ea6d9190c4621c0095e7a71 653 Gene3D G3DSA:3.40.50.410 461 642 7.9E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_21055 d97a81300ea6d9190c4621c0095e7a71 653 SMART SM00327 464 646 1.7E-7 T 12-10-2018 IPR002035 von Willebrand factor, type A AFR_21055 d97a81300ea6d9190c4621c0095e7a71 653 SUPERFAMILY SSF53300 467 639 1.36E-15 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFR_24550 e8222e9fd63b668c21d8eeedee9bdbd6 236 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 23 235 1.4E-50 T 12-10-2018 IPR015402 Protein of unknown function DUF1980 AFR_24550 e8222e9fd63b668c21d8eeedee9bdbd6 236 Pfam PF09323 Domain of unknown function (DUF1980) 6 107 4.0E-7 T 12-10-2018 IPR015402 Protein of unknown function DUF1980 AFR_39040 ccad8a822cd784e3b603c9d8027ee6b3 309 SMART SM01208 119 197 1.6E-17 T 12-10-2018 IPR011098 G5 domain AFR_39040 ccad8a822cd784e3b603c9d8027ee6b3 309 Gene3D G3DSA:2.20.230.10 120 196 4.4E-16 T 12-10-2018 AFR_39040 ccad8a822cd784e3b603c9d8027ee6b3 309 Pfam PF07501 G5 domain 123 194 5.2E-16 T 12-10-2018 IPR011098 G5 domain AFR_03870 77030a62439bf3b641936c90137e73dc 259 Pfam PF00285 Citrate synthase, C-terminal domain 41 241 6.4E-23 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFR_03870 77030a62439bf3b641936c90137e73dc 259 Gene3D G3DSA:1.10.580.10 38 241 3.8E-22 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFR_03870 77030a62439bf3b641936c90137e73dc 259 SUPERFAMILY SSF48256 9 242 1.44E-41 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFR_03870 77030a62439bf3b641936c90137e73dc 259 Gene3D G3DSA:1.10.230.10 105 212 3.8E-22 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFR_31295 52bd7a843b013081268b55587db9172b 191 SUPERFAMILY SSF53597 4 184 4.74E-26 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_31295 52bd7a843b013081268b55587db9172b 191 Gene3D G3DSA:3.40.430.10 4 183 1.3E-31 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_31295 52bd7a843b013081268b55587db9172b 191 Pfam PF01872 RibD C-terminal domain 5 179 1.0E-14 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_42675 3457238cc4546006fc928ecbae18c0e6 587 Gene3D G3DSA:3.60.21.10 368 548 1.3E-18 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_42675 3457238cc4546006fc928ecbae18c0e6 587 SUPERFAMILY SSF56300 369 585 2.88E-38 T 12-10-2018 AFR_42675 3457238cc4546006fc928ecbae18c0e6 587 Pfam PF00149 Calcineurin-like phosphoesterase 369 529 1.5E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_37645 910367feccb7281ee93597c6791098d8 108 SUPERFAMILY SSF46785 8 106 6.42E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_37645 910367feccb7281ee93597c6791098d8 108 Pfam PF01638 HxlR-like helix-turn-helix 23 104 7.1E-24 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFR_37645 910367feccb7281ee93597c6791098d8 108 Gene3D G3DSA:1.10.10.10 4 108 7.1E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_05720 e0b0f7720417c6afb101e5df999cfb24 60 Pfam PF03966 Trm112p-like protein 4 43 3.6E-8 T 12-10-2018 IPR005651 Trm112-like AFR_05720 e0b0f7720417c6afb101e5df999cfb24 60 SUPERFAMILY SSF158997 2 55 1.83E-15 T 12-10-2018 AFR_05720 e0b0f7720417c6afb101e5df999cfb24 60 Gene3D G3DSA:2.20.25.10 10 55 6.9E-17 T 12-10-2018 AFR_03610 2a824016e208304f6feac79fece567df 134 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 9 125 4.6E-35 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III AFR_28655 fe80ebe09be1e5cd0637f4e80be75cbd 131 Pfam PF12158 Protein of unknown function (DUF3592) 5 128 1.8E-12 T 12-10-2018 IPR021994 Protein of unknown function DUF3592 AFR_06790 eeaeb14d015df831d56a2e8c4e3307e2 315 Gene3D G3DSA:1.20.81.30 134 250 2.5E-7 T 12-10-2018 AFR_06790 eeaeb14d015df831d56a2e8c4e3307e2 315 Pfam PF00482 Type II secretion system (T2SS), protein F 148 272 4.0E-18 T 12-10-2018 IPR018076 Type II secretion system F domain AFR_28440 7b43fabeddab4eb336d9b87f3cca6715 135 SUPERFAMILY SSF55961 11 131 1.45E-19 T 12-10-2018 AFR_28440 7b43fabeddab4eb336d9b87f3cca6715 135 Gene3D G3DSA:3.30.530.20 7 134 9.3E-19 T 12-10-2018 IPR023393 START-like domain superfamily AFR_28440 7b43fabeddab4eb336d9b87f3cca6715 135 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 14 117 1.3E-9 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_30535 d3f38892c5db8082bd66f87b0ea5b20a 292 Pfam PF13845 Septum formation 49 268 1.4E-47 T 12-10-2018 IPR026004 Septum formation-related domain AFR_32985 7b8225f606112663baa7d6e845d02b07 183 SUPERFAMILY SSF48498 53 180 8.78E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFR_32985 7b8225f606112663baa7d6e845d02b07 183 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 64 175 4.2E-8 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFR_32985 7b8225f606112663baa7d6e845d02b07 183 Gene3D G3DSA:1.10.357.10 34 66 2.0E-12 T 12-10-2018 AFR_32985 7b8225f606112663baa7d6e845d02b07 183 Gene3D G3DSA:1.10.357.10 67 180 6.0E-8 T 12-10-2018 AFR_25730 9493c25060d21a5b028e67e264e291b3 390 Gene3D G3DSA:3.30.565.10 258 385 2.1E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_25730 9493c25060d21a5b028e67e264e291b3 390 Pfam PF07730 Histidine kinase 181 245 8.9E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_25730 9493c25060d21a5b028e67e264e291b3 390 SUPERFAMILY SSF55874 259 384 5.46E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_05915 170bc61cfb3f8c8a31ead5eb69ead08f 319 Gene3D G3DSA:1.10.10.2840 190 317 3.7E-10 T 12-10-2018 AFR_05915 170bc61cfb3f8c8a31ead5eb69ead08f 319 Pfam PF13556 PucR C-terminal helix-turn-helix domain 256 311 5.6E-10 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFR_18015 a24bf260e40db00f25dc214e05046bef 984 Gene3D G3DSA:3.30.379.10 30 196 1.1E-52 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_18015 a24bf260e40db00f25dc214e05046bef 984 Gene3D G3DSA:3.20.20.520 197 492 7.4E-110 T 12-10-2018 AFR_18015 a24bf260e40db00f25dc214e05046bef 984 SUPERFAMILY SSF55545 53 167 1.1E-5 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 AFR_18015 a24bf260e40db00f25dc214e05046bef 984 Pfam PF15979 Glycosyl hydrolase family 115 192 535 6.0E-129 T 12-10-2018 IPR031924 Glycosyl hydrolase family 115 AFR_18015 a24bf260e40db00f25dc214e05046bef 984 Gene3D G3DSA:2.60.120.1620 809 983 4.0E-56 T 12-10-2018 AFR_18015 a24bf260e40db00f25dc214e05046bef 984 Gene3D G3DSA:1.20.58.2150 494 691 1.9E-46 T 12-10-2018 AFR_02145 76b1f1ca97fc36019e53df5c36f0e38c 280 Gene3D G3DSA:3.40.50.1100 2 270 6.4E-73 T 12-10-2018 AFR_02145 76b1f1ca97fc36019e53df5c36f0e38c 280 Gene3D G3DSA:3.40.50.1100 14 109 6.4E-73 T 12-10-2018 AFR_02145 76b1f1ca97fc36019e53df5c36f0e38c 280 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 2 266 1.7E-62 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFR_02145 76b1f1ca97fc36019e53df5c36f0e38c 280 SUPERFAMILY SSF53686 2 274 5.37E-66 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFR_33745 eb5dd793d50ecf28a115c922d34754d8 282 Gene3D G3DSA:3.20.20.410 1 263 2.9E-43 T 12-10-2018 IPR036520 UPF0759 superfamily AFR_33745 eb5dd793d50ecf28a115c922d34754d8 282 Pfam PF01904 Protein of unknown function DUF72 26 257 1.3E-54 T 12-10-2018 IPR002763 Protein of unknown function DUF72 AFR_33745 eb5dd793d50ecf28a115c922d34754d8 282 SUPERFAMILY SSF117396 5 258 2.62E-67 T 12-10-2018 IPR036520 UPF0759 superfamily AFR_05835 575948d5aa9f260c1cdd77437e6443b4 150 Pfam PF10400 Virulence activator alpha C-term 74 145 3.5E-5 T 12-10-2018 IPR018309 Transcription regulator PadR, C-terminal AFR_05835 575948d5aa9f260c1cdd77437e6443b4 150 SUPERFAMILY SSF46785 1 146 8.94E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFR_05835 575948d5aa9f260c1cdd77437e6443b4 150 Gene3D G3DSA:1.10.10.10 1 69 7.1E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_28140 d92e5d5bfe29efdbc37a54a76e1c9a0e 317 SUPERFAMILY SSF53850 36 316 7.6E-48 T 12-10-2018 AFR_28140 d92e5d5bfe29efdbc37a54a76e1c9a0e 317 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 39 305 1.0E-39 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 AFR_28140 d92e5d5bfe29efdbc37a54a76e1c9a0e 317 Gene3D G3DSA:3.40.190.10 245 317 2.7E-8 T 12-10-2018 AFR_28140 d92e5d5bfe29efdbc37a54a76e1c9a0e 317 Gene3D G3DSA:3.40.190.100 122 244 2.4E-22 T 12-10-2018 AFR_28140 d92e5d5bfe29efdbc37a54a76e1c9a0e 317 Gene3D G3DSA:3.10.105.10 21 119 2.7E-8 T 12-10-2018 AFR_01585 24a06276456ad5fad47f2c1d930cfd7d 425 Pfam PF00535 Glycosyl transferase family 2 8 166 9.0E-24 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_01585 24a06276456ad5fad47f2c1d930cfd7d 425 SUPERFAMILY SSF53448 6 238 3.94E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_01585 24a06276456ad5fad47f2c1d930cfd7d 425 Gene3D G3DSA:3.90.550.10 2 227 1.5E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_02170 390b5f93dde594fd97bd75722acd3692 358 Pfam PF11268 Protein of unknown function (DUF3071) 1 171 5.0E-48 T 12-10-2018 IPR021421 Protein of unknown function DUF3071 AFR_17265 701f2c0e31b0e79d99c38b36f678b000 245 Pfam PF01925 Sulfite exporter TauE/SafE 4 234 2.3E-33 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFR_32355 e4d38b8986e1f854a3bc8227ec2e210e 374 Gene3D G3DSA:3.20.20.80 82 372 4.7E-41 T 12-10-2018 AFR_32355 e4d38b8986e1f854a3bc8227ec2e210e 374 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 191 323 1.9E-5 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AFR_32355 e4d38b8986e1f854a3bc8227ec2e210e 374 SUPERFAMILY SSF51445 84 358 1.13E-44 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFR_42135 a9ec47c2e7602089218e060696cdf704 145 Gene3D G3DSA:3.40.630.30 15 142 3.3E-5 T 12-10-2018 AFR_10150 ecd261e28aeea0765a29e34e9bdfbf87 414 Pfam PF00892 EamA-like transporter family 146 279 4.1E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_10150 ecd261e28aeea0765a29e34e9bdfbf87 414 Pfam PF00892 EamA-like transporter family 6 131 8.7E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFR_10150 ecd261e28aeea0765a29e34e9bdfbf87 414 SUPERFAMILY SSF103481 198 284 1.96E-11 T 12-10-2018 AFR_10150 ecd261e28aeea0765a29e34e9bdfbf87 414 SUPERFAMILY SSF103481 42 132 1.63E-10 T 12-10-2018 AFR_03195 7cdbf675d80178f1eba2b60d5025ff79 364 Gene3D G3DSA:2.120.10.30 8 361 1.7E-123 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_03195 7cdbf675d80178f1eba2b60d5025ff79 364 Pfam PF03022 Major royal jelly protein 80 350 8.6E-37 T 12-10-2018 IPR017996 Major royal jelly protein/protein yellow AFR_03195 7cdbf675d80178f1eba2b60d5025ff79 364 SUPERFAMILY SSF63829 23 333 5.23E-25 T 12-10-2018 AFR_01940 880d233898229dbd3a7f881d77afcecf 98 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 2 95 1.6E-6 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 AFR_02290 beac5ecc47e41f59c5de3e94e0ef68d3 298 Pfam PF01061 ABC-2 type transporter 56 256 5.9E-15 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_02290 beac5ecc47e41f59c5de3e94e0ef68d3 298 PIRSF PIRSF006648 57 293 3.5E-14 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_21810 91f6671513210f308dbef163a9555fb0 520 SUPERFAMILY SSF51703 5 519 6.04E-209 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFR_21810 91f6671513210f308dbef163a9555fb0 520 Gene3D G3DSA:3.20.20.440 3 520 2.4E-211 T 12-10-2018 IPR037086 D-Lysine 5,6-aminomutase alpha subunit superfamily AFR_21810 91f6671513210f308dbef163a9555fb0 520 Pfam PF09043 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 7 516 5.4E-245 T 12-10-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit AFR_25120 663911fabb25e5d18b3342489326095c 363 Gene3D G3DSA:1.10.10.2840 242 363 1.4E-20 T 12-10-2018 AFR_25120 663911fabb25e5d18b3342489326095c 363 Pfam PF13556 PucR C-terminal helix-turn-helix domain 306 362 1.6E-17 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFR_26125 ea7ca71c72818900fd3d0df28b4b24d4 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 305 2.8E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_26125 ea7ca71c72818900fd3d0df28b4b24d4 311 SUPERFAMILY SSF161098 72 298 8.24E-56 T 12-10-2018 IPR035906 MetI-like superfamily AFR_26125 ea7ca71c72818900fd3d0df28b4b24d4 311 Gene3D G3DSA:1.10.3720.10 68 310 2.3E-65 T 12-10-2018 IPR035906 MetI-like superfamily AFR_26575 2bbf9b6890522c2a209d4686c46d49ae 63 Pfam PF04149 Domain of unknown function (DUF397) 14 56 1.3E-13 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_17740 26ba5bee70294ed659f03714d9686000 152 SUPERFAMILY SSF50800 25 145 9.94E-16 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFR_22055 7be22fe6a81d4061845cfd000ca1c99e 166 SUPERFAMILY SSF47598 105 153 6.3E-9 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFR_07175 56fd523f13c7e9d3c476eabd15b10904 322 Pfam PF00005 ABC transporter 22 164 1.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_07175 56fd523f13c7e9d3c476eabd15b10904 322 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_07175 56fd523f13c7e9d3c476eabd15b10904 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 315 3.5E-112 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFR_07175 56fd523f13c7e9d3c476eabd15b10904 322 SMART SM00382 30 213 4.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_07175 56fd523f13c7e9d3c476eabd15b10904 322 SUPERFAMILY SSF52540 4 227 8.74E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_07175 56fd523f13c7e9d3c476eabd15b10904 322 Gene3D G3DSA:3.40.50.300 1 237 3.1E-64 T 12-10-2018 AFR_39050 ebc33b12fe959c8434c1c4c9bac2713f 190 Gene3D G3DSA:3.40.50.360 1 189 4.9E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_39050 ebc33b12fe959c8434c1c4c9bac2713f 190 Pfam PF03358 NADPH-dependent FMN reductase 2 144 1.4E-37 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFR_39050 ebc33b12fe959c8434c1c4c9bac2713f 190 SUPERFAMILY SSF52218 1 161 4.19E-39 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFR_27120 f4a298068a31f2947b4eb5ecf0d1cb83 242 SUPERFAMILY SSF81301 21 68 2.22E-7 T 12-10-2018 AFR_27120 f4a298068a31f2947b4eb5ecf0d1cb83 242 Pfam PF01909 Nucleotidyltransferase domain 17 53 4.0E-6 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFR_25870 fc63c1003d4c43fe3b56159f63dad5aa 360 Gene3D G3DSA:1.50.10.150 15 355 3.4E-19 T 12-10-2018 IPR038665 Voltage-dependent anion channel superfamily AFR_25870 fc63c1003d4c43fe3b56159f63dad5aa 360 Pfam PF03595 Voltage-dependent anion channel 21 345 7.2E-64 T 12-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 AFR_37290 1ac91aa4cf42c9d924756086ec315936 263 Pfam PF01061 ABC-2 type transporter 14 218 2.1E-28 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_37290 1ac91aa4cf42c9d924756086ec315936 263 PIRSF PIRSF006648 13 262 4.2E-33 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_20865 bbf012193606f2c437cd3ce7ce7657a8 113 Gene3D G3DSA:3.40.30.10 6 101 2.0E-5 T 12-10-2018 AFR_27105 7af64565f0a0048855aba9691647279e 436 SUPERFAMILY SSF56112 129 403 5.31E-14 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_27105 7af64565f0a0048855aba9691647279e 436 Gene3D G3DSA:3.90.1200.10 198 436 7.4E-94 T 12-10-2018 AFR_21755 020701fc40a7511607b4edf3511848f3 235 SUPERFAMILY SSF55961 3 132 6.65E-14 T 12-10-2018 AFR_21755 020701fc40a7511607b4edf3511848f3 235 Gene3D G3DSA:3.30.530.20 1 135 3.3E-13 T 12-10-2018 IPR023393 START-like domain superfamily AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 ProSitePatterns PS00622 LuxR-type HTH domain signature. 682 709 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 Gene3D G3DSA:1.10.10.10 643 723 2.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 SUPERFAMILY SSF46894 656 722 7.48E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 SMART SM00421 665 722 1.6E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 698 710 6.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 668 682 6.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 682 698 6.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_27440 5451c18b83d7db50fb5cb433730bb21c 724 Pfam PF00196 Bacterial regulatory proteins, luxR family 668 720 7.9E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFR_20395 fbf82618d5e09a64b49024f99c320486 335 SUPERFAMILY SSF51412 4 314 4.76E-41 T 12-10-2018 AFR_20395 fbf82618d5e09a64b49024f99c320486 335 Gene3D G3DSA:3.20.20.70 2 335 4.7E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_20395 fbf82618d5e09a64b49024f99c320486 335 Pfam PF03060 Nitronate monooxygenase 7 334 4.1E-70 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFR_37895 17769443bdccd3fab3748616f4a92729 269 SUPERFAMILY SSF89392 52 247 7.06E-6 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFR_14040 6d5be0ba30e7086bb873a2ecd0d0ad8b 183 Gene3D G3DSA:2.60.40.1890 42 153 4.0E-30 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily AFR_14040 6d5be0ba30e7086bb873a2ecd0d0ad8b 183 SUPERFAMILY SSF110087 26 153 6.93E-35 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily AFR_14040 6d5be0ba30e7086bb873a2ecd0d0ad8b 183 Pfam PF04314 Copper chaperone PCu(A)C 38 144 7.4E-33 T 12-10-2018 IPR007410 Copper chaperone PCuAC AFR_07055 2c42a1645875c8821f451d32188653f9 247 PIRSF PIRSF008292 1 235 4.4E-87 T 12-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 AFR_07055 2c42a1645875c8821f451d32188653f9 247 Gene3D G3DSA:3.60.21.10 1 226 2.3E-13 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFR_07055 2c42a1645875c8821f451d32188653f9 247 Pfam PF00149 Calcineurin-like phosphoesterase 2 76 1.1E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFR_07055 2c42a1645875c8821f451d32188653f9 247 SUPERFAMILY SSF56300 2 224 8.14E-28 T 12-10-2018 AFR_21875 9dcf85212978ec81d52521ad80ab88a0 136 Pfam PF04237 YjbR 13 110 2.0E-7 T 12-10-2018 IPR007351 Uncharacterised protein YjbR AFR_26455 363bc04a3b19316248fc23a4922ce810 263 Pfam PF13349 Putative adhesin 20 253 7.4E-21 T 12-10-2018 IPR025164 Putative adhesin AFR_30540 b01b5871bc7641935d1c717ca570d075 212 SUPERFAMILY SSF52540 2 194 1.35E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30540 b01b5871bc7641935d1c717ca570d075 212 Gene3D G3DSA:3.40.50.300 1 211 4.1E-68 T 12-10-2018 AFR_14285 211ecf08b209e65197b289405be8ce87 355 Pfam PF03773 Predicted permease 68 333 1.4E-22 T 12-10-2018 IPR005524 Predicted permease DUF318 AFR_33490 d1aa5fbb84c16dca9c9fb982987964fa 304 Pfam PF02424 ApbE family 20 281 1.8E-49 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 AFR_33490 d1aa5fbb84c16dca9c9fb982987964fa 304 SUPERFAMILY SSF143631 14 286 2.62E-53 T 12-10-2018 IPR003374 ApbE-like superfamily AFR_33490 d1aa5fbb84c16dca9c9fb982987964fa 304 Gene3D G3DSA:3.10.520.20 11 300 3.0E-58 T 12-10-2018 AFR_01455 64e507f52a6d7d411c776a8985432ae0 376 PRINTS PR01217 Proline rich extensin signature 125 141 3.0E-10 T 12-10-2018 AFR_01455 64e507f52a6d7d411c776a8985432ae0 376 PRINTS PR01217 Proline rich extensin signature 98 119 3.0E-10 T 12-10-2018 AFR_01455 64e507f52a6d7d411c776a8985432ae0 376 PRINTS PR01217 Proline rich extensin signature 62 78 3.0E-10 T 12-10-2018 AFR_01455 64e507f52a6d7d411c776a8985432ae0 376 PRINTS PR01217 Proline rich extensin signature 84 96 3.0E-10 T 12-10-2018 AFR_12525 ed86416c2f82d78e6e0313377e4c1a3f 221 Pfam PF13349 Putative adhesin 49 219 7.9E-9 T 12-10-2018 IPR025164 Putative adhesin AFR_04355 9fe37351a20daa542d4a002e4ce8b5da 381 Gene3D G3DSA:2.120.10.10 37 193 7.1E-10 T 12-10-2018 AFR_09180 cd74d1f6aba03cf51fcd386cdc7c9c2e 113 SUPERFAMILY SSF54593 6 112 6.73E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_09180 cd74d1f6aba03cf51fcd386cdc7c9c2e 113 Gene3D G3DSA:3.10.180.10 1 113 2.9E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_30050 681d16c25f2ecb256aead0933cab1250 144 Gene3D G3DSA:3.30.10.20 74 141 6.6E-8 T 12-10-2018 AFR_30050 681d16c25f2ecb256aead0933cab1250 144 SMART SM00740 72 143 0.0073 T 12-10-2018 IPR005543 PASTA domain AFR_30050 681d16c25f2ecb256aead0933cab1250 144 Pfam PF03793 PASTA domain 77 140 1.3E-4 T 12-10-2018 IPR005543 PASTA domain AFR_08865 ee453c0fe2eab6edbeeddb3bfaf4ddd2 277 SUPERFAMILY SSF53335 18 242 4.96E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_08865 ee453c0fe2eab6edbeeddb3bfaf4ddd2 277 Pfam PF13649 Methyltransferase domain 44 140 1.3E-11 T 12-10-2018 AFR_08865 ee453c0fe2eab6edbeeddb3bfaf4ddd2 277 Gene3D G3DSA:3.40.50.150 2 209 1.0E-30 T 12-10-2018 AFR_06050 282ed069b96d956de163b2edb0e50d3d 240 Gene3D G3DSA:3.40.50.720 1 228 4.6E-30 T 12-10-2018 AFR_06050 282ed069b96d956de163b2edb0e50d3d 240 SUPERFAMILY SSF51735 3 228 5.03E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_06050 282ed069b96d956de163b2edb0e50d3d 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 197 8.2E-16 T 12-10-2018 AFR_02915 65ac102cff065b88511a06e282ff1b55 531 Pfam PF00561 alpha/beta hydrolase fold 90 455 2.7E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_02915 65ac102cff065b88511a06e282ff1b55 531 SUPERFAMILY SSF53474 90 469 2.2E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_42365 db17da41aa7f42b91bb9239b0f10f441 298 Pfam PF01694 Rhomboid family 131 264 2.1E-34 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AFR_42365 db17da41aa7f42b91bb9239b0f10f441 298 SUPERFAMILY SSF144091 67 270 1.44E-38 T 12-10-2018 AFR_42365 db17da41aa7f42b91bb9239b0f10f441 298 Gene3D G3DSA:1.20.1540.10 113 275 3.3E-38 T 12-10-2018 IPR035952 Rhomboid-like superfamily AFR_04255 99f9724579e739576976b429f93d9836 175 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 158 3.7E-33 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_04255 99f9724579e739576976b429f93d9836 175 Gene3D G3DSA:1.20.120.1200 5 162 4.1E-37 T 12-10-2018 AFR_22990 892f922ec76223514f890b2adbfc087d 209 Pfam PF09335 SNARE associated Golgi protein 31 151 2.3E-12 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_13195 118039512204354575f3c77892a3119d 302 SUPERFAMILY SSF161098 62 290 6.28E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13195 118039512204354575f3c77892a3119d 302 Gene3D G3DSA:1.10.3720.10 58 300 1.7E-60 T 12-10-2018 IPR035906 MetI-like superfamily AFR_13195 118039512204354575f3c77892a3119d 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 290 2.3E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_24345 b89da43c950e76fa6f680fc79a585969 192 Pfam PF04138 GtrA-like protein 15 145 2.2E-15 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 AFR_03160 06123c750f27ab60e7116e9718eda891 387 SUPERFAMILY SSF103473 16 374 3.01E-23 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_03160 06123c750f27ab60e7116e9718eda891 387 Gene3D G3DSA:1.20.1250.20 7 373 1.4E-23 T 12-10-2018 AFR_03160 06123c750f27ab60e7116e9718eda891 387 Pfam PF07690 Major Facilitator Superfamily 16 308 2.7E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_21555 ac2f05da3bb882263cb2072108da6e98 403 Pfam PF07730 Histidine kinase 197 264 2.7E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_21555 ac2f05da3bb882263cb2072108da6e98 403 SUPERFAMILY SSF55874 310 390 1.74E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21555 ac2f05da3bb882263cb2072108da6e98 403 Gene3D G3DSA:3.30.565.10 275 400 4.9E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_30760 97473c26ff66d249fcd29f1566ffbd32 137 SUPERFAMILY SSF55729 22 127 3.26E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_30760 97473c26ff66d249fcd29f1566ffbd32 137 Gene3D G3DSA:3.40.630.30 8 132 2.6E-20 T 12-10-2018 AFR_30760 97473c26ff66d249fcd29f1566ffbd32 137 Pfam PF00583 Acetyltransferase (GNAT) family 50 122 5.0E-9 T 12-10-2018 IPR000182 GNAT domain AFR_16885 d2d5f05de4122e8afe4f589d9b230a60 250 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 5 181 1.8E-21 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_16885 d2d5f05de4122e8afe4f589d9b230a60 250 SUPERFAMILY SSF52266 1 190 2.9E-32 T 12-10-2018 AFR_16885 d2d5f05de4122e8afe4f589d9b230a60 250 Gene3D G3DSA:3.40.50.1110 2 193 4.2E-25 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_42425 cd7003c5e6981f45d1ce1feb16e8d0a2 499 Pfam PF13727 CoA-binding domain 94 267 1.3E-11 T 12-10-2018 AFR_42425 cd7003c5e6981f45d1ce1feb16e8d0a2 499 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 45 499 1.2E-119 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AFR_42425 cd7003c5e6981f45d1ce1feb16e8d0a2 499 Pfam PF02397 Bacterial sugar transferase 307 493 1.2E-64 T 12-10-2018 IPR003362 Bacterial sugar transferase AFR_22895 f091aa5ddcc3b260a5cbef34bd9098e8 205 SUPERFAMILY SSF51735 1 198 4.33E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_22895 f091aa5ddcc3b260a5cbef34bd9098e8 205 Pfam PF13460 NAD(P)H-binding 7 194 1.6E-25 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_22895 f091aa5ddcc3b260a5cbef34bd9098e8 205 Gene3D G3DSA:3.40.50.720 1 200 1.4E-26 T 12-10-2018 AFR_00280 aedd1d8e50a2c381b4dd0c4acba5a38c 483 Pfam PF01098 Cell cycle protein 76 453 2.7E-72 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFR_01595 784d4b73802c05677dca9659d37f50d1 318 Gene3D G3DSA:3.20.20.70 1 154 3.2E-45 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_01595 784d4b73802c05677dca9659d37f50d1 318 SUPERFAMILY SSF51395 3 313 3.72E-79 T 12-10-2018 AFR_01595 784d4b73802c05677dca9659d37f50d1 318 PIRSF PIRSF000138 1 318 3.4E-100 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AFR_01595 784d4b73802c05677dca9659d37f50d1 318 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 212 218 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AFR_01595 784d4b73802c05677dca9659d37f50d1 318 Pfam PF01070 FMN-dependent dehydrogenase 3 314 3.7E-98 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AFR_01595 784d4b73802c05677dca9659d37f50d1 318 Gene3D G3DSA:3.20.20.70 155 317 8.5E-56 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_14870 5e67adf32b4023a76e3023807556b07a 243 SUPERFAMILY SSF48452 28 177 1.52E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_14870 5e67adf32b4023a76e3023807556b07a 243 Gene3D G3DSA:1.25.40.10 5 221 2.5E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_14870 5e67adf32b4023a76e3023807556b07a 243 Pfam PF07721 Tetratricopeptide repeat 41 64 0.23 T 12-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 AFR_14870 5e67adf32b4023a76e3023807556b07a 243 Pfam PF07721 Tetratricopeptide repeat 81 101 0.12 T 12-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 AFR_21740 823a58a080a57ab0ac5e41055f9027ec 197 SUPERFAMILY SSF54197 71 189 3.61E-10 T 12-10-2018 IPR036265 HIT-like superfamily AFR_21740 823a58a080a57ab0ac5e41055f9027ec 197 Gene3D G3DSA:3.30.428.10 55 191 2.7E-7 T 12-10-2018 IPR036265 HIT-like superfamily AFR_41160 2d0f6f20b639b31af8d09678abd40a12 173 Pfam PF06271 RDD family 4 141 3.0E-18 T 12-10-2018 IPR010432 RDD AFR_31345 eb515fcf7b5899c438db5708c6571f82 154 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 128 5.8E-17 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 AFR_31345 eb515fcf7b5899c438db5708c6571f82 154 Gene3D G3DSA:3.30.530.20 2 137 1.2E-35 T 12-10-2018 IPR023393 START-like domain superfamily AFR_31345 eb515fcf7b5899c438db5708c6571f82 154 SUPERFAMILY SSF55961 3 138 5.3E-25 T 12-10-2018 AFR_00330 3273044c75fc30ec4df20174b387f07e 220 Gene3D G3DSA:1.10.3630.10 1 211 9.2E-32 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily AFR_00330 3273044c75fc30ec4df20174b387f07e 220 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 3 201 1.1E-49 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 AFR_35075 e1d84ebad99512457f14ab7d4997562b 743 Pfam PF02687 FtsX-like permease family 266 353 3.9E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_42650 4bad083c8abb5725675595524c4a2109 491 Pfam PF13830 Domain of unknown function (DUF4192) 23 331 9.4E-76 T 12-10-2018 IPR025447 Protein of unknown function DUF4192 AFR_17585 5f2f35cf454723198a4c499b27dd47c2 678 Pfam PF01968 Hydantoinase/oxoprolinase 197 482 1.3E-89 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFR_17585 5f2f35cf454723198a4c499b27dd47c2 678 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 1 176 2.5E-47 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFR_31205 63c949265b6487b5d0d6e952e5942884 325 Pfam PF00248 Aldo/keto reductase family 16 313 3.0E-58 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_31205 63c949265b6487b5d0d6e952e5942884 325 Gene3D G3DSA:3.20.20.100 2 323 1.1E-73 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_31205 63c949265b6487b5d0d6e952e5942884 325 SUPERFAMILY SSF51430 2 317 1.83E-73 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_38260 79119fc958f360f0de7c6dfa20fd49e7 730 SUPERFAMILY SSF82866 130 330 9.02E-27 T 12-10-2018 AFR_38260 79119fc958f360f0de7c6dfa20fd49e7 730 Pfam PF03176 MMPL family 45 364 1.1E-47 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_38260 79119fc958f360f0de7c6dfa20fd49e7 730 Pfam PF03176 MMPL family 459 700 5.7E-32 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_38260 79119fc958f360f0de7c6dfa20fd49e7 730 SUPERFAMILY SSF82866 460 696 7.59E-24 T 12-10-2018 AFR_21180 09e91c395308c1136b52f98d938bbce2 248 Pfam PF10127 Predicted nucleotidyltransferase 16 241 6.4E-42 T 12-10-2018 IPR018775 Nucleotidyltransferase, predicted AFR_36810 912446e70629bc5ca1fb7295a419c69b 485 Gene3D G3DSA:1.50.10.20 79 308 2.1E-7 T 12-10-2018 AFR_36810 912446e70629bc5ca1fb7295a419c69b 485 SUPERFAMILY SSF48208 183 341 9.07E-9 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_05685 82568d3017b0fa867a0e4b213e3e42e9 185 Pfam PF11937 Protein of unknown function (DUF3455) 98 184 2.4E-14 T 12-10-2018 IPR021851 Protein of unknown function DUF3455 AFR_24810 9bc4826f756a743445031fd3b84c414c 104 SUPERFAMILY SSF50118 1 103 2.03E-9 T 12-10-2018 AFR_24810 9bc4826f756a743445031fd3b84c414c 104 Gene3D G3DSA:2.30.30.110 1 102 3.5E-6 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFR_24810 9bc4826f756a743445031fd3b84c414c 104 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 102 1.4E-5 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFR_23325 a4071814758638d1a041c7598004b195 304 Gene3D G3DSA:3.40.50.12080 26 127 2.7E-11 T 12-10-2018 AFR_24780 3f636649d80e8ddf1b5142dd89239ad7 243 Pfam PF05853 beta-keto acid cleavage enzyme 10 240 1.2E-24 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 AFR_24780 3f636649d80e8ddf1b5142dd89239ad7 243 Gene3D G3DSA:3.20.20.70 4 241 2.7E-30 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_21995 d1b7fbefb015580704cfcfcf2fd1f130 305 Gene3D G3DSA:1.20.1260.130 2 267 6.2E-76 T 12-10-2018 AFR_21995 d1b7fbefb015580704cfcfcf2fd1f130 305 SUPERFAMILY SSF47240 1 266 1.5E-83 T 12-10-2018 IPR009078 Ferritin-like superfamily AFR_21995 d1b7fbefb015580704cfcfcf2fd1f130 305 Pfam PF05067 Manganese containing catalase 1 266 8.7E-88 T 12-10-2018 IPR007760 Manganese catalase AFR_25510 fdc7551af2ec151f9d5459b3af92f548 423 Pfam PF07394 Protein of unknown function (DUF1501) 56 387 7.7E-32 T 12-10-2018 IPR010869 Protein of unknown function DUF1501 AFR_01210 0e4187fd8d93ae60b2bb449b3eb6e062 288 SUPERFAMILY SSF52091 161 271 1.06E-17 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01210 0e4187fd8d93ae60b2bb449b3eb6e062 288 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 12 107 4.7E-23 T 12-10-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain AFR_01210 0e4187fd8d93ae60b2bb449b3eb6e062 288 Gene3D G3DSA:3.30.750.24 157 278 2.7E-36 T 12-10-2018 IPR036513 STAS domain superfamily AFR_01210 0e4187fd8d93ae60b2bb449b3eb6e062 288 Pfam PF01740 STAS domain 168 266 1.9E-9 T 12-10-2018 IPR002645 STAS domain AFR_09090 489e3a37aaf9645d4b40d8b14287181e 580 Pfam PF09594 Glycosyltransferase family 87 60 295 2.6E-57 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 AFR_35280 47d3eb11e41d15108545c7f58a5e958d 269 Pfam PF11361 Protein of unknown function (DUF3159) 49 245 8.6E-55 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 AFR_23715 2dd61f0275a80e3931d1b211a3f8ae8c 311 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 300 2.8E-39 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFR_23715 2dd61f0275a80e3931d1b211a3f8ae8c 311 SUPERFAMILY SSF53213 3 304 1.16E-59 T 12-10-2018 AFR_00760 8eeef0831d75c05ae42344e2ac0e70b7 72 Pfam PF11273 Protein of unknown function (DUF3073) 2 63 1.8E-24 T 12-10-2018 IPR021426 Protein of unknown function DUF3073 AFR_32870 5123e98158a8a23d2d7af50ee18f90f3 610 Pfam PF13203 Putative metallopeptidase domain 229 354 6.7E-16 T 12-10-2018 IPR025154 Putative metallopeptidase domain AFR_32115 8f2c433c0cc07b205ab1d3bf00d02088 468 Pfam PF00754 F5/8 type C domain 47 157 1.8E-26 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain AFR_32115 8f2c433c0cc07b205ab1d3bf00d02088 468 SUPERFAMILY SSF49785 45 162 2.98E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32115 8f2c433c0cc07b205ab1d3bf00d02088 468 Gene3D G3DSA:2.60.120.260 34 162 7.0E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFR_32115 8f2c433c0cc07b205ab1d3bf00d02088 468 Pfam PF09362 Domain of unknown function (DUF1996) 219 426 8.7E-43 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_38540 46877e0f29d2092afc83234529ba7bd0 197 Pfam PF01810 LysE type translocator 14 196 9.2E-44 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_19115 98e9fee3e027a4056f916330a20355f9 160 Gene3D G3DSA:1.10.10.10 69 139 5.3E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_19115 98e9fee3e027a4056f916330a20355f9 160 Pfam PF08281 Sigma-70, region 4 90 134 1.1E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFR_19115 98e9fee3e027a4056f916330a20355f9 160 SUPERFAMILY SSF88659 78 135 4.58E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFR_10975 97e2b9564a083d1e9ae5c8763da455ae 225 SUPERFAMILY SSF49329 92 219 4.54E-7 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFR_10975 97e2b9564a083d1e9ae5c8763da455ae 225 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 101 219 9.4E-7 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFR_10975 97e2b9564a083d1e9ae5c8763da455ae 225 Gene3D G3DSA:2.60.40.200 88 222 1.6E-10 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFR_37000 9379849ce6f44b72da5f8cbe4ceab19c 131 SUPERFAMILY SSF50118 33 128 6.1E-10 T 12-10-2018 AFR_37000 9379849ce6f44b72da5f8cbe4ceab19c 131 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 34 127 9.5E-8 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFR_12990 a30090186fd08c4161714abe27374adf 354 SUPERFAMILY SSF51430 8 323 7.6E-96 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_12990 a30090186fd08c4161714abe27374adf 354 Pfam PF00248 Aldo/keto reductase family 20 323 7.6E-74 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFR_12990 a30090186fd08c4161714abe27374adf 354 Gene3D G3DSA:3.20.20.100 7 346 2.6E-115 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFR_05235 f0f43f8bbe8d364e493c12c5d93d6904 236 Pfam PF12730 ABC-2 family transporter protein 20 151 3.3E-11 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_00445 bae1ad3b1021e75b96919f9a144a368e 282 Gene3D G3DSA:3.40.50.720 6 270 7.3E-77 T 12-10-2018 AFR_00445 bae1ad3b1021e75b96919f9a144a368e 282 Pfam PF13460 NAD(P)H-binding 7 182 2.2E-20 T 12-10-2018 IPR016040 NAD(P)-binding domain AFR_00445 bae1ad3b1021e75b96919f9a144a368e 282 SUPERFAMILY SSF51735 2 243 8.24E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_00445 bae1ad3b1021e75b96919f9a144a368e 282 Gene3D G3DSA:3.90.25.10 143 274 7.3E-77 T 12-10-2018 AFR_31845 846f88b583bff28b281e26faee7d793c 165 Pfam PF04306 Protein of unknown function (DUF456) 26 161 1.3E-27 T 12-10-2018 IPR007403 Protein of unknown function DUF456 AFR_20085 e32f013f464c853fd0bf01a02b80e195 286 SUPERFAMILY SSF48452 140 261 3.52E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_20085 e32f013f464c853fd0bf01a02b80e195 286 Gene3D G3DSA:1.25.40.10 123 281 2.2E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06820 c8499f2233dcd99c075f482990d96ac4 64 Pfam PF04964 Flp/Fap pilin component 17 58 1.4E-15 T 12-10-2018 IPR007047 Flp/Fap pilin component AFR_39945 cc95817217988f28063017bcd6a1c713 280 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 11 253 5.8E-51 T 12-10-2018 IPR018713 Domain of unknown function DUF2236 AFR_38175 e31093867c7e3eab25bfa9e052e5e1d2 378 Pfam PF07730 Histidine kinase 185 220 8.5E-6 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_38175 e31093867c7e3eab25bfa9e052e5e1d2 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 283 371 7.6E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_38175 e31093867c7e3eab25bfa9e052e5e1d2 378 SUPERFAMILY SSF55874 272 372 5.63E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38175 e31093867c7e3eab25bfa9e052e5e1d2 378 SMART SM00387 275 374 0.0044 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFR_38175 e31093867c7e3eab25bfa9e052e5e1d2 378 Gene3D G3DSA:3.30.565.10 247 372 3.6E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_41640 441678fcb17f9a32892eb5e634bfe7c3 163 Gene3D G3DSA:3.30.1330.40 10 163 6.9E-62 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_41640 441678fcb17f9a32892eb5e634bfe7c3 163 SUPERFAMILY SSF55298 14 162 1.88E-55 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFR_41640 441678fcb17f9a32892eb5e634bfe7c3 163 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 17 162 2.0E-33 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFR_03285 3d60d6f3b13aab5d90f962ef0334367f 245 Pfam PF02754 Cysteine-rich domain 134 218 8.6E-15 T 12-10-2018 IPR004017 Cysteine-rich domain AFR_03285 3d60d6f3b13aab5d90f962ef0334367f 245 Pfam PF02754 Cysteine-rich domain 3 83 7.6E-16 T 12-10-2018 IPR004017 Cysteine-rich domain AFR_17620 35bb28d854df19dfd4e4987c11298b39 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 297 1.7E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_17620 35bb28d854df19dfd4e4987c11298b39 304 Gene3D G3DSA:1.10.3720.10 18 295 1.1E-57 T 12-10-2018 IPR035906 MetI-like superfamily AFR_17620 35bb28d854df19dfd4e4987c11298b39 304 SUPERFAMILY SSF161098 27 304 2.15E-49 T 12-10-2018 IPR035906 MetI-like superfamily AFR_17545 fab86ed0aadcee540a8d5f928d90ee1a 515 Gene3D G3DSA:3.40.50.1110 239 514 2.3E-53 T 12-10-2018 IPR036514 SGNH hydrolase superfamily AFR_17545 fab86ed0aadcee540a8d5f928d90ee1a 515 SUPERFAMILY SSF52266 241 511 4.79E-39 T 12-10-2018 AFR_17545 fab86ed0aadcee540a8d5f928d90ee1a 515 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 246 502 9.3E-10 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFR_27325 2b45e166a68618131affe9be36c64448 326 SUPERFAMILY SSF56219 4 325 1.96E-29 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_27325 2b45e166a68618131affe9be36c64448 326 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 316 9.6E-10 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_27325 2b45e166a68618131affe9be36c64448 326 Gene3D G3DSA:3.60.10.10 2 326 2.1E-28 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_34485 c577f7a9a352b468312d7d96bad996a0 363 Gene3D G3DSA:1.25.40.10 158 356 4.9E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_34485 c577f7a9a352b468312d7d96bad996a0 363 Gene3D G3DSA:1.25.40.10 18 157 1.2E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_20385 435e6b7cd82f354ca5afdda28fbff52e 540 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 49 236 1.3E-12 T 12-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 AFR_08795 000fcbcf0a288c3a734e6086775b1cab 143 Pfam PF11253 Protein of unknown function (DUF3052) 15 137 4.0E-53 T 12-10-2018 IPR021412 Protein of unknown function DUF3052 AFR_05195 615cd1d7321c24423cfc919bd67d7f85 406 SUPERFAMILY SSF56112 163 316 3.47E-7 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_25425 9a419e812a26bc07ef431ffdd232c1a9 312 SUPERFAMILY SSF64182 9 305 2.62E-9 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily AFR_25425 9a419e812a26bc07ef431ffdd232c1a9 312 PIRSF PIRSF028235 1 307 2.1E-142 T 12-10-2018 IPR016877 Uncharacterised conserved protein UCP028235 AFR_34950 e80f5cd0f8565686fb40ec3c2404d360 62 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 28 58 1.0E-7 T 12-10-2018 AFR_38460 0ebff77591ae0758740856dcf1d8d429 243 Pfam PF01553 Acyltransferase 22 148 1.4E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_38460 0ebff77591ae0758740856dcf1d8d429 243 SMART SM00563 37 151 1.3E-32 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFR_38460 0ebff77591ae0758740856dcf1d8d429 243 SUPERFAMILY SSF69593 16 207 5.89E-34 T 12-10-2018 AFR_19905 28204dea275cff35df63d5357d667d1d 838 Pfam PF02687 FtsX-like permease family 742 830 1.0E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_19905 28204dea275cff35df63d5357d667d1d 838 Pfam PF02687 FtsX-like permease family 296 392 8.7E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_03865 6f1f599c1fb20641424a342c4958b741 287 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 261 4.1E-27 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFR_03865 6f1f599c1fb20641424a342c4958b741 287 SUPERFAMILY SSF53213 2 280 1.14E-50 T 12-10-2018 AFR_03865 6f1f599c1fb20641424a342c4958b741 287 Gene3D G3DSA:3.40.830.10 1 283 4.9E-63 T 12-10-2018 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 ProSitePatterns PS00221 MIP family signature. 59 67 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 Pfam PF00230 Major intrinsic protein 3 238 1.1E-50 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 Gene3D G3DSA:1.20.1080.10 1 246 5.8E-82 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 238 6.1E-64 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 PRINTS PR00783 Major intrinsic protein family signature 139 157 3.5E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 PRINTS PR00783 Major intrinsic protein family signature 172 194 3.5E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 PRINTS PR00783 Major intrinsic protein family signature 221 241 3.5E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 PRINTS PR00783 Major intrinsic protein family signature 78 97 3.5E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 PRINTS PR00783 Major intrinsic protein family signature 3 22 3.5E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 PRINTS PR00783 Major intrinsic protein family signature 41 65 3.5E-48 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFR_27455 16e6f4f29cb7c5c36ef74b3c58a5f875 270 SUPERFAMILY SSF81338 3 242 2.88E-66 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFR_31490 4fabd1ce370648c85abc2f3c2c2dea7b 387 Gene3D G3DSA:3.90.1200.10 210 362 1.4E-8 T 12-10-2018 AFR_31490 4fabd1ce370648c85abc2f3c2c2dea7b 387 SUPERFAMILY SSF56112 140 349 1.7E-17 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_31490 4fabd1ce370648c85abc2f3c2c2dea7b 387 Pfam PF01636 Phosphotransferase enzyme family 152 324 9.4E-12 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_20880 57fb1eeb7d8347d348ac9f1aa2ce6cf2 270 Pfam PF14344 Domain of unknown function (DUF4397) 33 148 1.3E-21 T 12-10-2018 IPR025510 Domain of unknown function DUF4397 AFR_05790 03de7ce633f20f7f5f843f43832d0eaa 377 SUPERFAMILY SSF55729 2 175 2.16E-40 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05790 03de7ce633f20f7f5f843f43832d0eaa 377 Gene3D G3DSA:3.40.630.30 2 184 2.7E-40 T 12-10-2018 AFR_05790 03de7ce633f20f7f5f843f43832d0eaa 377 Pfam PF13302 Acetyltransferase (GNAT) domain 12 150 1.2E-24 T 12-10-2018 IPR000182 GNAT domain AFR_05790 03de7ce633f20f7f5f843f43832d0eaa 377 Pfam PF13302 Acetyltransferase (GNAT) domain 200 339 4.4E-22 T 12-10-2018 IPR000182 GNAT domain AFR_05790 03de7ce633f20f7f5f843f43832d0eaa 377 SUPERFAMILY SSF55729 195 363 1.6E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_05790 03de7ce633f20f7f5f843f43832d0eaa 377 Gene3D G3DSA:3.40.630.30 194 364 4.1E-36 T 12-10-2018 AFR_18660 c4089cd5ad4405f9b82d5bd44d18da5c 728 SUPERFAMILY SSF89372 182 315 1.12E-8 T 12-10-2018 AFR_18660 c4089cd5ad4405f9b82d5bd44d18da5c 728 SUPERFAMILY SSF89372 18 209 1.05E-11 T 12-10-2018 AFR_22355 85a89b8cdcc57b04c5a8f2728bfb33fa 378 SUPERFAMILY SSF51679 3 367 8.68E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22355 85a89b8cdcc57b04c5a8f2728bfb33fa 378 Gene3D G3DSA:3.20.20.30 1 377 1.6E-118 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_22355 85a89b8cdcc57b04c5a8f2728bfb33fa 378 Pfam PF00296 Luciferase-like monooxygenase 18 284 1.1E-33 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_22355 85a89b8cdcc57b04c5a8f2728bfb33fa 378 PIRSF PIRSF000337 290 376 1.2E-17 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFR_22355 85a89b8cdcc57b04c5a8f2728bfb33fa 378 PIRSF PIRSF000337 1 299 4.3E-64 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFR_03400 47148aff436295fd81efcb68a532e038 141 SUPERFAMILY SSF47413 43 85 1.56E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_03400 47148aff436295fd81efcb68a532e038 141 Gene3D G3DSA:1.10.260.40 5 134 3.5E-44 T 12-10-2018 AFR_32130 43f8b21d00788fbc106d60985132d374 366 Pfam PF01699 Sodium/calcium exchanger protein 36 188 3.2E-14 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFR_32130 43f8b21d00788fbc106d60985132d374 366 Pfam PF01699 Sodium/calcium exchanger protein 222 363 2.4E-13 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFR_26345 af27076bfd5269ccc37c97c833204a98 121 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 98 18.927 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFR_26345 af27076bfd5269ccc37c97c833204a98 121 Pfam PF02416 mttA/Hcf106 family 6 55 2.2E-16 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFR_05850 9ad280f60dd43c3f5fa9961810778d2b 291 PIRSF PIRSF003097 1 291 5.0E-82 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 AFR_05850 9ad280f60dd43c3f5fa9961810778d2b 291 Gene3D G3DSA:3.30.70.3040 43 153 1.6E-25 T 12-10-2018 AFR_29725 8782e218b0744d41bb53593fa69c7696 224 Gene3D G3DSA:3.40.630.100 29 224 7.0E-46 T 12-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily AFR_29725 8782e218b0744d41bb53593fa69c7696 224 Pfam PF05908 Poly-gamma-glutamate hydrolase 34 206 6.1E-41 T 12-10-2018 IPR008585 Poly-gamma-glutamate hydrolase AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 Gene3D G3DSA:2.40.10.120 83 286 1.2E-64 T 12-10-2018 AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 SUPERFAMILY SSF50494 86 283 1.75E-54 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 2.6E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 PRINTS PR00834 HtrA/DegQ protease family signature 186 210 2.6E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 PRINTS PR00834 HtrA/DegQ protease family signature 123 135 2.6E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 PRINTS PR00834 HtrA/DegQ protease family signature 145 165 2.6E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 2.6E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFR_36780 acbb068bbeed1e59c8d9f413299671ca 286 Pfam PF13365 Trypsin-like peptidase domain 114 251 1.3E-32 T 12-10-2018 AFR_36165 b3af39b54b9bfaa434801085ae2e9310 709 SUPERFAMILY SSF82866 127 332 5.23E-33 T 12-10-2018 AFR_36165 b3af39b54b9bfaa434801085ae2e9310 709 Gene3D G3DSA:1.20.1640.10 154 336 2.9E-13 T 12-10-2018 AFR_36165 b3af39b54b9bfaa434801085ae2e9310 709 SUPERFAMILY SSF82866 459 678 1.19E-26 T 12-10-2018 AFR_36165 b3af39b54b9bfaa434801085ae2e9310 709 Pfam PF03176 MMPL family 444 678 8.3E-29 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_36165 b3af39b54b9bfaa434801085ae2e9310 709 Pfam PF03176 MMPL family 45 361 4.4E-52 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFR_23495 82a3142349bfdec81a91305f01f2cc8b 230 Pfam PF00535 Glycosyl transferase family 2 14 153 3.9E-18 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_23495 82a3142349bfdec81a91305f01f2cc8b 230 SUPERFAMILY SSF53448 12 208 6.68E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_23495 82a3142349bfdec81a91305f01f2cc8b 230 Gene3D G3DSA:3.90.550.10 11 230 5.5E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_07590 93223b41507e35d5db93cb559bc7b045 120 Pfam PF14017 Protein of unknown function (DUF4233) 21 118 9.7E-21 T 12-10-2018 IPR025327 Protein of unknown function DUF4233 AFR_20855 886f3cc043e8f0e6a3ba97e1fc785ce8 200 Gene3D G3DSA:3.40.50.150 2 185 1.6E-40 T 12-10-2018 AFR_20855 886f3cc043e8f0e6a3ba97e1fc785ce8 200 SUPERFAMILY SSF53335 2 184 5.31E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_20855 886f3cc043e8f0e6a3ba97e1fc785ce8 200 Pfam PF13649 Methyltransferase domain 38 129 1.1E-19 T 12-10-2018 AFR_15500 982908cfbaaf855029f610717d991c99 125 Pfam PF14106 Domain of unknown function (DUF4279) 13 113 9.6E-11 T 12-10-2018 IPR025459 Protein of unknown function DUF4279 AFR_13080 044dfd53b164ffd1cec0c2923f6a486f 775 Pfam PF02538 Hydantoinase B/oxoprolinase 45 601 4.6E-122 T 12-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFR_13245 42eb668bd39c5023946f2f6db68b0aab 544 Gene3D G3DSA:3.20.20.80 46 397 1.5E-17 T 12-10-2018 AFR_13245 42eb668bd39c5023946f2f6db68b0aab 544 SUPERFAMILY SSF50405 448 542 1.37E-14 T 12-10-2018 IPR008999 Actin-crosslinking AFR_13245 42eb668bd39c5023946f2f6db68b0aab 544 Gene3D G3DSA:2.80.10.50 401 544 1.3E-24 T 12-10-2018 AFR_21970 2586c3aad028ceeb106f99e2d2975af0 198 Pfam PF13411 MerR HTH family regulatory protein 36 89 2.4E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_21970 2586c3aad028ceeb106f99e2d2975af0 198 SUPERFAMILY SSF46955 37 100 1.74E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_21970 2586c3aad028ceeb106f99e2d2975af0 198 Gene3D G3DSA:1.10.1660.10 35 197 1.9E-8 T 12-10-2018 AFR_33075 161e4b4553b8deb9117f67a72835d9c4 328 SUPERFAMILY SSF51556 52 289 3.99E-32 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFR_33075 161e4b4553b8deb9117f67a72835d9c4 328 Gene3D G3DSA:3.20.20.140 54 292 6.7E-38 T 12-10-2018 AFR_34660 3bc11ef42549664f1eee0f229a88c933 215 Gene3D G3DSA:1.20.144.10 68 199 9.7E-17 T 12-10-2018 AFR_34660 3bc11ef42549664f1eee0f229a88c933 215 SUPERFAMILY SSF48317 32 206 4.58E-29 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFR_34660 3bc11ef42549664f1eee0f229a88c933 215 SMART SM00014 84 197 2.1E-8 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_34660 3bc11ef42549664f1eee0f229a88c933 215 Pfam PF01569 PAP2 superfamily 87 198 1.6E-16 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFR_14370 7aff604737afe7d95735044c485b1286 155 Pfam PF07080 Protein of unknown function (DUF1348) 11 140 9.5E-64 T 12-10-2018 IPR009783 Protein of unknown function DUF1348 AFR_14370 7aff604737afe7d95735044c485b1286 155 Gene3D G3DSA:3.10.450.50 14 153 4.8E-65 T 12-10-2018 AFR_14370 7aff604737afe7d95735044c485b1286 155 SUPERFAMILY SSF54427 6 144 4.93E-70 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_20210 d504d3d84568fe9b7ef23dd8a78f6f59 392 Pfam PF07907 YibE/F-like protein 137 373 1.2E-65 T 12-10-2018 IPR012507 YibE/F-like AFR_06635 717e71055c25eb6a5864267f9474fa51 463 Gene3D G3DSA:3.50.50.60 35 400 2.2E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_06635 717e71055c25eb6a5864267f9474fa51 463 Gene3D G3DSA:3.30.9.10 129 360 2.2E-58 T 12-10-2018 AFR_06635 717e71055c25eb6a5864267f9474fa51 463 Pfam PF01266 FAD dependent oxidoreductase 35 389 6.6E-52 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFR_06635 717e71055c25eb6a5864267f9474fa51 463 SUPERFAMILY SSF51905 10 316 1.62E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_40945 d599d8960b929b749c97e2a1b8e83d9a 152 Gene3D G3DSA:3.40.1350.120 2 150 4.1E-41 T 12-10-2018 AFR_41870 78c0fb2c4696a1a8daacc029b7a6756a 112 Pfam PF10990 Protein of unknown function (DUF2809) 3 80 1.6E-20 T 12-10-2018 IPR021257 Protein of unknown function DUF2809 AFR_10445 cbe032dddd0be3991d715dd876869523 72 Pfam PF11160 Protein of unknown function (DUF2945) 10 69 6.7E-24 T 12-10-2018 IPR021331 Protein of unknown function DUF2945 AFR_08465 9f4baee2ef1cfebbce5bba805412ef4e 288 SUPERFAMILY SSF56112 1 252 1.93E-35 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_08465 9f4baee2ef1cfebbce5bba805412ef4e 288 Pfam PF01636 Phosphotransferase enzyme family 28 227 6.6E-20 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_08465 9f4baee2ef1cfebbce5bba805412ef4e 288 Gene3D G3DSA:3.90.1200.10 99 262 1.1E-14 T 12-10-2018 AFR_38365 cda0d98aee1933c24337e615e04fad09 314 Pfam PF09362 Domain of unknown function (DUF1996) 81 285 4.1E-44 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_24205 92ac51c7c12105c60c14f25fc266b63d 246 Pfam PF00005 ABC transporter 25 171 8.6E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFR_24205 92ac51c7c12105c60c14f25fc266b63d 246 SMART SM00382 34 219 2.7E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_24205 92ac51c7c12105c60c14f25fc266b63d 246 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFR_24205 92ac51c7c12105c60c14f25fc266b63d 246 SUPERFAMILY SSF52540 6 223 1.66E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_24205 92ac51c7c12105c60c14f25fc266b63d 246 Gene3D G3DSA:3.40.50.300 3 243 6.7E-72 T 12-10-2018 AFR_31675 06c8a40ff3dbc0f970e4b63af94c774e 245 Pfam PF00756 Putative esterase 10 241 2.7E-25 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFR_31675 06c8a40ff3dbc0f970e4b63af94c774e 245 SUPERFAMILY SSF53474 6 245 1.63E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_31675 06c8a40ff3dbc0f970e4b63af94c774e 245 Gene3D G3DSA:3.40.50.1820 1 245 1.1E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_10520 2cc2e7c4f9599124b6a8629263fce0ee 232 SUPERFAMILY SSF109854 3 152 6.11E-40 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_10520 2cc2e7c4f9599124b6a8629263fce0ee 232 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 146 1.0E-27 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 AFR_10520 2cc2e7c4f9599124b6a8629263fce0ee 232 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 12 211 1.7E-32 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type AFR_10520 2cc2e7c4f9599124b6a8629263fce0ee 232 Gene3D G3DSA:1.20.120.450 8 150 1.7E-43 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_10520 2cc2e7c4f9599124b6a8629263fce0ee 232 SUPERFAMILY SSF55718 157 231 6.0E-11 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFR_32240 280325bd0319da233418e95363668c3e 201 SUPERFAMILY SSF56214 90 197 9.07E-14 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_32240 280325bd0319da233418e95363668c3e 201 PRINTS PR01399 Enterobactin synthetase component D signature 26 46 8.4E-24 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 AFR_32240 280325bd0319da233418e95363668c3e 201 PRINTS PR01399 Enterobactin synthetase component D signature 56 74 8.4E-24 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 AFR_32240 280325bd0319da233418e95363668c3e 201 PRINTS PR01399 Enterobactin synthetase component D signature 133 149 8.4E-24 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 AFR_32240 280325bd0319da233418e95363668c3e 201 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 90 168 2.9E-11 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFR_22605 96485c889b3d8ae55c8b9d8b9d2950c5 261 SUPERFAMILY SSF53474 9 256 1.49E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22605 96485c889b3d8ae55c8b9d8b9d2950c5 261 Pfam PF12697 Alpha/beta hydrolase family 32 248 2.9E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_22605 96485c889b3d8ae55c8b9d8b9d2950c5 261 Gene3D G3DSA:3.40.50.1820 8 259 9.5E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_02130 4a0aa2e06688b53c33896693be5e658b 445 Pfam PF00860 Permease family 1 399 4.6E-25 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 AFR_00515 3834294a7cac2691846cbfb02275b520 781 Pfam PF00350 Dynamin family 271 316 1.2E-4 T 12-10-2018 IPR022812 Dynamin superfamily AFR_00515 3834294a7cac2691846cbfb02275b520 781 SUPERFAMILY SSF52540 255 455 2.4E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_42750 6359e8da6e07531c1d14c147aee698ca 125 Pfam PF13453 Transcription factor zinc-finger 1 32 2.8E-12 T 12-10-2018 IPR027392 Transcription factor zinc-finger AFR_26760 ba3a5085d90e3a24577f5153df1b6c34 125 SUPERFAMILY SSF51182 28 117 3.63E-8 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_26760 ba3a5085d90e3a24577f5153df1b6c34 125 Gene3D G3DSA:2.60.120.10 24 118 4.4E-7 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_08130 c0a34ecce52111d4d59a0b9c8e3a6b23 123 SUPERFAMILY SSF103196 2 121 6.28E-5 T 12-10-2018 AFR_20640 e7301fdedaeb7d87b77f97afbb63badd 417 Pfam PF08811 Protein of unknown function (DUF1800) 9 415 9.2E-92 T 12-10-2018 IPR014917 Protein of unknown function DUF1800 AFR_05190 472689e797e7c001e930c73cb675bab6 292 Pfam PF00685 Sulfotransferase domain 33 242 1.3E-15 T 12-10-2018 IPR000863 Sulfotransferase domain GO:0008146 AFR_05190 472689e797e7c001e930c73cb675bab6 292 Gene3D G3DSA:3.40.50.300 18 291 3.3E-62 T 12-10-2018 AFR_05190 472689e797e7c001e930c73cb675bab6 292 SUPERFAMILY SSF52540 28 286 8.97E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_30335 d8d344ba91c162ba818588fa6d07d1f0 281 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 182 1.3E-22 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFR_30335 d8d344ba91c162ba818588fa6d07d1f0 281 Gene3D G3DSA:3.40.50.720 1 281 9.2E-44 T 12-10-2018 AFR_30335 d8d344ba91c162ba818588fa6d07d1f0 281 SUPERFAMILY SSF51735 1 278 8.95E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_05305 c98661ddbfead6404f2ad33b39a11399 538 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 535 2.1E-101 T 12-10-2018 IPR010281 Protein of unknown function DUF885 AFR_29445 941a078b060bca674f18ff07e8a65fe6 164 SUPERFAMILY SSF54427 10 160 1.21E-29 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_29445 941a078b060bca674f18ff07e8a65fe6 164 Gene3D G3DSA:3.10.450.50 9 161 2.1E-34 T 12-10-2018 AFR_29445 941a078b060bca674f18ff07e8a65fe6 164 Pfam PF13577 SnoaL-like domain 13 147 4.6E-26 T 12-10-2018 IPR037401 SnoaL-like domain AFR_36035 da06bf1f6bef4c51c7cb9a2324a1c1f7 245 SUPERFAMILY SSF52317 25 234 1.78E-39 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_36035 da06bf1f6bef4c51c7cb9a2324a1c1f7 245 Pfam PF07722 Peptidase C26 1 217 1.6E-51 T 12-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 AFR_36035 da06bf1f6bef4c51c7cb9a2324a1c1f7 245 Gene3D G3DSA:3.40.50.880 1 237 1.6E-60 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_35145 3f0e9237cae0e80c9ca3644f944dc8e9 71 Pfam PF04149 Domain of unknown function (DUF397) 11 65 1.3E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_09055 7a9073a6fb4af47b94cc8f8ab804cec2 382 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 11 357 2.7E-91 T 12-10-2018 IPR010640 Low temperature requirement A AFR_40680 5b7f995adf37b1738e2a07ddd058d6e7 277 Pfam PF05853 beta-keto acid cleavage enzyme 5 273 1.5E-82 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 AFR_40680 5b7f995adf37b1738e2a07ddd058d6e7 277 Gene3D G3DSA:3.20.20.70 2 276 8.9E-84 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFR_38325 c40ab40996ce49615ec299ad3763a92b 167 Gene3D G3DSA:3.30.2010.10 68 154 9.7E-12 T 12-10-2018 AFR_38325 c40ab40996ce49615ec299ad3763a92b 167 Pfam PF01863 Protein of unknown function DUF45 58 153 5.1E-22 T 12-10-2018 IPR002725 Protein of unknown function DUF45 AFR_10740 071401d116e7465e3a1efc7a7d62fed2 198 Pfam PF01810 LysE type translocator 16 197 1.4E-17 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_04805 d203600b693a0f4e42f24af1eedf3afb 280 Gene3D G3DSA:2.60.40.2880 190 278 6.8E-12 T 12-10-2018 IPR038468 Transport accessory protein MmpS, soluble domain superfamily AFR_04805 d203600b693a0f4e42f24af1eedf3afb 280 Pfam PF05423 Mycobacterium membrane protein 184 269 1.7E-7 T 12-10-2018 IPR008693 Transport accessory protein MmpS AFR_15410 75e9303df72d47baab8f1329176ffac9 109 Gene3D G3DSA:3.10.180.10 1 109 3.7E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_15410 75e9303df72d47baab8f1329176ffac9 109 SUPERFAMILY SSF54593 2 108 1.3E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_39300 a0077e1ba285e043439535cd42ebb967 196 Pfam PF04138 GtrA-like protein 31 156 1.1E-24 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 AFR_14820 d39064ea2901c66f992091058c378ad5 58 Pfam PF06348 Protein of unknown function (DUF1059) 3 57 8.7E-19 T 12-10-2018 IPR009409 Protein of unknown function DUF1059 AFR_38335 734e7b11e41e9f09257ec1b8b11aa534 383 SUPERFAMILY SSF69572 122 270 3.66E-12 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFR_02225 4c9329da4aeeefa293b108969749a8f5 98 PIRSF PIRSF006909 1 98 2.2E-47 T 12-10-2018 IPR014447 Uncharacterised conserved protein UCP006909 AFR_41935 50006c3a0222791d1cad8cafebf88ac2 556 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 552 2.0E-162 T 12-10-2018 IPR010281 Protein of unknown function DUF885 AFR_22935 fb94b5ae710a06746f7a2c1bfe01f56d 123 Pfam PF14087 Domain of unknown function (DUF4267) 15 119 2.2E-19 T 12-10-2018 IPR025363 Protein of unknown function DUF4267 AFR_39955 5b22c1f435bf403ffc928c94bc7e6841 296 Pfam PF12705 PD-(D/E)XK nuclease superfamily 28 274 1.2E-28 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AFR_42295 19fa693da7e1cac444df76f0eafbef7d 286 Pfam PF09362 Domain of unknown function (DUF1996) 30 244 1.0E-50 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 AFR_06555 972409ea176da5deb8dde3a88b46602d 730 Gene3D G3DSA:3.40.50.300 353 612 2.3E-30 T 12-10-2018 AFR_06555 972409ea176da5deb8dde3a88b46602d 730 SUPERFAMILY SSF52540 343 562 5.45E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_13620 b7d26a968a1bbabab927a605a6383cf5 123 Pfam PF10012 Uncharacterized protein conserved in bacteria (DUF2255) 10 120 7.8E-35 T 12-10-2018 IPR016888 Uncharacterised conserved protein UCP028498 AFR_26030 f7845e1daf40d62b9f2642aa7072276d 268 Pfam PF14378 PAP2 superfamily 46 223 3.3E-42 T 12-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 AFR_09410 33e31e5f5bc67807706888bd94a095da 147 SUPERFAMILY SSF52172 6 134 1.51E-6 T 12-10-2018 IPR011006 CheY-like superfamily AFR_09410 33e31e5f5bc67807706888bd94a095da 147 Gene3D G3DSA:3.40.50.2300 9 137 1.5E-5 T 12-10-2018 AFR_30720 5a321a064b2c8792a8042446058a549c 154 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 102 1.4E-26 T 12-10-2018 IPR009293 Uncharacterised protein family UPF0478 AFR_25000 ece44b23949dfe5f2b6bcdc8774f1ad5 300 SUPERFAMILY SSF53448 9 217 5.39E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_25000 ece44b23949dfe5f2b6bcdc8774f1ad5 300 Gene3D G3DSA:3.90.550.10 3 253 2.0E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFR_25000 ece44b23949dfe5f2b6bcdc8774f1ad5 300 Pfam PF00535 Glycosyl transferase family 2 6 106 5.2E-21 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFR_37110 dcca02b7ba5f5080a9da7b2cdd2caedc 142 Pfam PF04134 Protein of unknown function, DUF393 21 117 5.8E-11 T 12-10-2018 IPR007263 Protein of unknown function DUF393 AFR_40815 9a7eddf132a80a26be10001d2bc93b31 168 Gene3D G3DSA:2.40.380.10 52 165 6.2E-12 T 12-10-2018 IPR035930 FomD-like superfamily AFR_40815 9a7eddf132a80a26be10001d2bc93b31 168 SUPERFAMILY SSF159234 6 162 2.75E-21 T 12-10-2018 IPR035930 FomD-like superfamily AFR_40815 9a7eddf132a80a26be10001d2bc93b31 168 Pfam PF04167 Protein of unknown function (DUF402) 56 120 3.7E-13 T 12-10-2018 IPR007295 Domain of unknown function DUF402 AFR_17850 8baa87a62adf60a700278afb73c9361c 254 SUPERFAMILY SSF53335 3 172 2.41E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_17850 8baa87a62adf60a700278afb73c9361c 254 Pfam PF13649 Methyltransferase domain 49 146 2.9E-13 T 12-10-2018 AFR_01760 0a4bec79d1b6dc63f5e9a9fa02a74857 128 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 116 1.2E-26 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV AFR_32230 8bb4c8503ac43a25b6ee83b95579eb99 239 Pfam PF00795 Carbon-nitrogen hydrolase 3 238 1.1E-30 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFR_32230 8bb4c8503ac43a25b6ee83b95579eb99 239 SUPERFAMILY SSF56317 1 238 1.96E-54 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_32230 8bb4c8503ac43a25b6ee83b95579eb99 239 Gene3D G3DSA:3.60.110.10 1 239 2.3E-53 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_22010 b9eb9322971fe802f348e2798fa63d95 45 SUPERFAMILY SSF55904 1 43 1.03E-8 T 12-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 AFR_35855 e1eb2dc4cb4f1ca357b0292bd30552e8 413 Pfam PF06224 Winged helix DNA-binding domain 40 380 2.8E-78 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 AFR_41140 fd2e854ede2873dbfa82da374ddc7a35 438 SUPERFAMILY SSF50998 213 414 1.33E-7 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFR_41140 fd2e854ede2873dbfa82da374ddc7a35 438 Gene3D G3DSA:2.130.10.10 209 431 6.0E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_41140 fd2e854ede2873dbfa82da374ddc7a35 438 Pfam PF13360 PQQ-like domain 264 407 3.5E-8 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFR_08435 d31f756c7483a19d0cc3980d8be5ad4f 134 SUPERFAMILY SSF47413 6 71 8.28E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFR_08435 d31f756c7483a19d0cc3980d8be5ad4f 134 SMART SM00530 13 69 0.0028 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFR_08435 d31f756c7483a19d0cc3980d8be5ad4f 134 Gene3D G3DSA:1.10.260.40 6 76 2.0E-6 T 12-10-2018 AFR_31570 2f0a951570e9e07424a855c9c3b5fb9c 369 Gene3D G3DSA:3.40.190.10 97 315 7.0E-34 T 12-10-2018 AFR_31570 2f0a951570e9e07424a855c9c3b5fb9c 369 Gene3D G3DSA:3.40.190.10 197 288 7.0E-34 T 12-10-2018 AFR_31570 2f0a951570e9e07424a855c9c3b5fb9c 369 SUPERFAMILY SSF53850 99 325 2.86E-25 T 12-10-2018 AFR_31570 2f0a951570e9e07424a855c9c3b5fb9c 369 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 114 317 1.6E-24 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_31570 2f0a951570e9e07424a855c9c3b5fb9c 369 SMART SM00062 100 332 1.3E-9 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFR_30470 68ca0b26021e4c31b771b2ee1ba7a10f 142 Pfam PF10756 Bacterial PH domain 65 134 6.6E-19 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 AFR_39090 6ad300f73428dfdd9464cbf4153ebe59 114 Gene3D G3DSA:3.10.490.10 1 113 7.3E-19 T 12-10-2018 AFR_39090 6ad300f73428dfdd9464cbf4153ebe59 114 SUPERFAMILY SSF110857 4 112 1.31E-14 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily AFR_39090 6ad300f73428dfdd9464cbf4153ebe59 114 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 110 1.8E-11 T 12-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like AFR_20345 b95e1ebea47751ce2ee326d2cdaedb80 167 Gene3D G3DSA:1.20.120.520 1 141 1.6E-6 T 12-10-2018 AFR_20345 b95e1ebea47751ce2ee326d2cdaedb80 167 Pfam PF01814 Hemerythrin HHE cation binding domain 4 121 6.1E-10 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFR_23100 908de4a6c85a0125d175a1c827e8abf5 110 SUPERFAMILY SSF54593 8 108 2.4E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_23100 908de4a6c85a0125d175a1c827e8abf5 110 Gene3D G3DSA:3.10.180.10 3 110 1.2E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_25235 6efdfdd284582de83f25c9223d63e3c1 312 Pfam PF01636 Phosphotransferase enzyme family 75 246 1.4E-7 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_25235 6efdfdd284582de83f25c9223d63e3c1 312 SUPERFAMILY SSF56112 4 297 1.37E-15 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_02040 1ae8433e5e214db416ef3f8730584344 153 Pfam PF09990 Predicted membrane protein (DUF2231) 45 138 7.6E-12 T 12-10-2018 IPR019251 Domain of unknown function DUF2231, transmembrane AFR_39745 89aa00736f157fe60fb4448c0151bed1 309 Pfam PF00685 Sulfotransferase domain 164 290 3.1E-9 T 12-10-2018 IPR000863 Sulfotransferase domain GO:0008146 AFR_39745 89aa00736f157fe60fb4448c0151bed1 309 SUPERFAMILY SSF52540 5 290 6.07E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_25995 674e327ea7014fe77ea8ddc577aacfcd 92 TIGRFAM TIGR04042 MSMEG_0570_fam: MSMEG_0570 family protein 2 80 3.4E-29 T 12-10-2018 IPR023846 Conserved hypothetical protein CHP04042, MSMEG0570 AFR_21780 8a46591c63f291cad33a50ae93348c09 176 Pfam PF04186 FxsA cytoplasmic membrane protein 12 117 1.7E-27 T 12-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 AFR_34135 9204b0a36291a6682640c7ddf57c8343 512 SUPERFAMILY SSF69318 231 505 9.02E-28 T 12-10-2018 AFR_34135 9204b0a36291a6682640c7ddf57c8343 512 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 251 323 9.6E-9 T 12-10-2018 AFR_34135 9204b0a36291a6682640c7ddf57c8343 512 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 369 437 3.1E-6 T 12-10-2018 AFR_25420 da95c6f69cf49c1d3a9540dfe69f7abe 308 Pfam PF07987 Domain of unkown function (DUF1775) 68 190 4.4E-17 T 12-10-2018 IPR012533 YcnI-like AFR_25420 da95c6f69cf49c1d3a9540dfe69f7abe 308 Gene3D G3DSA:2.60.40.2230 65 219 8.0E-15 T 12-10-2018 IPR038507 YcnI-like superfamily AFR_13125 b0b7f516cb20de89d0355ac840d77eb5 200 SUPERFAMILY SSF52317 1 191 8.84E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_13125 b0b7f516cb20de89d0355ac840d77eb5 200 Pfam PF01965 DJ-1/PfpI family 1 174 2.4E-25 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFR_13125 b0b7f516cb20de89d0355ac840d77eb5 200 Gene3D G3DSA:3.40.50.880 1 198 8.4E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_42865 5ecf7d4438753be6e743b63205f31f12 155 Pfam PF17249 Family of unknown function (DUF5318) 1 128 3.2E-67 T 12-10-2018 IPR035169 Protein of unknown function DUF5318 AFR_35560 558f6c56d1a0e2b571be526c1d5f70c6 402 Pfam PF03993 Domain of Unknown Function (DUF349) 93 166 1.5E-14 T 12-10-2018 IPR007139 Protein of unknown function DUF349 AFR_35560 558f6c56d1a0e2b571be526c1d5f70c6 402 Pfam PF03993 Domain of Unknown Function (DUF349) 170 242 2.4E-19 T 12-10-2018 IPR007139 Protein of unknown function DUF349 AFR_35560 558f6c56d1a0e2b571be526c1d5f70c6 402 Pfam PF03993 Domain of Unknown Function (DUF349) 248 320 8.4E-22 T 12-10-2018 IPR007139 Protein of unknown function DUF349 AFR_07090 1220841b279665e40fb3eb357c8bb99b 108 Pfam PF12823 Domain of unknown function (DUF3817) 5 93 3.9E-28 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane AFR_07090 1220841b279665e40fb3eb357c8bb99b 108 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 8 91 8.6E-32 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane AFR_15785 66e057bb2c372f6b0e9d00611e05c32a 337 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 304 336 0.0022 T 12-10-2018 AFR_14625 48e4fefd1308a4b91145dab4eba60d75 207 Pfam PF06197 Protein of unknown function (DUF998) 4 195 1.1E-19 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_05260 ff4478b4b71b8568dd5bf1068fee3207 520 Pfam PF01186 Lysyl oxidase 359 503 1.6E-13 T 12-10-2018 IPR001695 Lysyl oxidase GO:0005507|GO:0016641|GO:0055114 Reactome: R-HSA-1566948|Reactome: R-HSA-2243919 AFR_31220 42040a05b055be6b9b101df75d82497a 90 Pfam PF14019 Protein of unknown function (DUF4235) 10 86 1.9E-28 T 12-10-2018 IPR025329 Protein of unknown function DUF4235 AFR_40085 aa5ec90987b19d0dccae514594efd2a0 270 PIRSF PIRSF020623 1 264 1.7E-66 T 12-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 AFR_40085 aa5ec90987b19d0dccae514594efd2a0 270 Gene3D G3DSA:1.10.10.10 1 83 4.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFR_40085 aa5ec90987b19d0dccae514594efd2a0 270 Pfam PF08223 PaaX-like protein C-terminal domain 160 253 3.0E-28 T 12-10-2018 IPR013225 PaaX-like, C-terminal AFR_40085 aa5ec90987b19d0dccae514594efd2a0 270 Pfam PF07848 PaaX-like protein 3 68 1.9E-18 T 12-10-2018 IPR012906 PaaX-like, N-terminal AFR_40085 aa5ec90987b19d0dccae514594efd2a0 270 Gene3D G3DSA:1.20.58.1460 182 262 4.6E-8 T 12-10-2018 AFR_21725 0ba7787179fc438b8701c76306a0ec4f 67 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 14 67 1.4E-15 T 12-10-2018 IPR012667 Cobalt transporter subunit CbtB, putative AFR_11435 f0811d57887d7bec867702193c5257ee 260 Pfam PF11958 Domain of unknown function (DUF3472) 111 205 2.8E-13 T 12-10-2018 IPR021862 Protein of unknown function DUF3472 AFR_16485 3e672afeffa33bcd55f5096ff1150083 287 Gene3D G3DSA:3.60.10.10 28 287 4.3E-21 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_16485 3e672afeffa33bcd55f5096ff1150083 287 SUPERFAMILY SSF56219 28 281 3.27E-19 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFR_16485 3e672afeffa33bcd55f5096ff1150083 287 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 71 277 9.8E-7 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFR_21700 02ed8ab57fcd885321c99c41607b8c1f 373 Gene3D G3DSA:3.30.565.10 246 370 1.4E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_21700 02ed8ab57fcd885321c99c41607b8c1f 373 Pfam PF07730 Histidine kinase 176 241 7.5E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_21700 02ed8ab57fcd885321c99c41607b8c1f 373 SUPERFAMILY SSF55874 254 369 1.88E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_09710 cf9fa664e3a91e508ae2d853365281c1 122 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 1 90 2.0E-15 T 12-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 AFR_27140 d47e240bfff4395059218df875094482 112 SUPERFAMILY SSF51306 17 80 3.66E-5 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFR_31885 b91a40789f5df9795d8657d0508342a4 154 Gene3D G3DSA:3.40.50.300 1 153 3.1E-14 T 12-10-2018 AFR_25715 a06d4df967f9e161fc5af242ef1b7ccb 309 Gene3D G3DSA:3.40.50.1820 3 308 1.1E-74 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_25715 a06d4df967f9e161fc5af242ef1b7ccb 309 Pfam PF07859 alpha/beta hydrolase fold 77 280 1.9E-49 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFR_25715 a06d4df967f9e161fc5af242ef1b7ccb 309 SUPERFAMILY SSF53474 53 305 1.76E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_13440 dafd91020c882333e99717f678545da0 125 Pfam PF05331 Protein of unknown function (DUF742) 15 123 1.6E-28 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_05780 efdea545a778656bc391b633ae07415e 274 SUPERFAMILY SSF53271 180 241 3.12E-8 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFR_05780 efdea545a778656bc391b633ae07415e 274 Gene3D G3DSA:3.40.50.2020 160 251 2.8E-8 T 12-10-2018 AFR_19160 50093fd3f4f2b3cdf0b98bbcb23970ba 188 Gene3D G3DSA:1.20.1260.10 21 185 7.2E-42 T 12-10-2018 IPR012347 Ferritin-like AFR_19160 50093fd3f4f2b3cdf0b98bbcb23970ba 188 Pfam PF03713 Domain of unknown function (DUF305) 32 183 2.6E-38 T 12-10-2018 IPR005183 Domain of unknown function DUF305 AFR_39525 44ea9944f44fedac640329fe793f9efd 172 Pfam PF14024 Protein of unknown function (DUF4240) 48 124 2.9E-7 T 12-10-2018 IPR025334 Domain of unknown function (DUF4240 AFR_36005 7aa6646fd2a169a808d5b880975bc09d 236 Gene3D G3DSA:3.30.460.10 8 124 6.9E-15 T 12-10-2018 AFR_36005 7aa6646fd2a169a808d5b880975bc09d 236 SUPERFAMILY SSF81301 17 120 1.69E-7 T 12-10-2018 AFR_09330 62245c1cb107da70a56997f1daa1a0ee 243 Pfam PF03591 AzlC protein 19 152 2.1E-35 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease AFR_34910 75acb2074d25812d10897ac47c263663 321 SUPERFAMILY SSF53098 2 311 1.14E-65 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFR_32660 9d3bff98cc5a0ab063bda7d5f9660795 345 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 41 300 2.7E-22 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_32660 9d3bff98cc5a0ab063bda7d5f9660795 345 Pfam PF03631 Virulence factor BrkB 47 302 1.8E-40 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_32660 9d3bff98cc5a0ab063bda7d5f9660795 345 PIRSF PIRSF035875 20 321 1.1E-48 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_37440 39cffc0158584daafb26a3ce33be7852 210 Pfam PF09414 RNA ligase 36 187 1.4E-19 T 12-10-2018 IPR021122 RNA ligase domain, REL/Rln2 AFR_37440 39cffc0158584daafb26a3ce33be7852 210 Gene3D G3DSA:3.30.470.30 25 177 7.3E-12 T 12-10-2018 AFR_37440 39cffc0158584daafb26a3ce33be7852 210 SUPERFAMILY SSF56091 11 201 2.3E-26 T 12-10-2018 AFR_21835 0a8f44647dfad60f37bfbe7ad3b52247 238 Gene3D G3DSA:3.40.50.150 7 210 2.6E-37 T 12-10-2018 AFR_21835 0a8f44647dfad60f37bfbe7ad3b52247 238 Pfam PF08241 Methyltransferase domain 39 127 2.1E-19 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_21835 0a8f44647dfad60f37bfbe7ad3b52247 238 SUPERFAMILY SSF53335 7 180 2.5E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_38665 d1529dc65da6be42b2591e3ef5621d5d 558 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 76 240 4.4E-6 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFR_26360 1b2aa55394af11490186ea443e05b834 331 Pfam PF13280 WYL domain 152 318 1.2E-29 T 12-10-2018 IPR026881 WYL domain AFR_31235 ba97823bd99f1fd064a65c90a9b6bddb 391 SUPERFAMILY SSF50182 171 236 3.07E-13 T 12-10-2018 IPR010920 LSM domain superfamily AFR_31235 ba97823bd99f1fd064a65c90a9b6bddb 391 Pfam PF00924 Mechanosensitive ion channel 129 274 2.1E-24 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFR_33415 f9070ec0db92406fa52f52fa9b212eeb 465 Pfam PF14224 Domain of unknown function (DUF4331) 36 455 3.5E-158 T 12-10-2018 IPR025566 Protein of unknown function DUF4331 AFR_42165 1100614237afa2962f7e9ba7b030b188 216 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 10 207 1.4E-26 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 AFR_17445 129a9ac5bbaed6a7deb74d9c05976279 170 Gene3D G3DSA:1.25.10.10 12 156 1.2E-5 T 12-10-2018 IPR011989 Armadillo-like helical AFR_30595 788a28f651441de9c5e81b08de078cd1 105 SUPERFAMILY SSF46946 48 102 1.26E-6 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFR_30595 788a28f651441de9c5e81b08de078cd1 105 Gene3D G3DSA:1.10.8.50 1 105 1.5E-41 T 12-10-2018 AFR_36105 01b821e32f13ecfd16ae4d935de41245 355 Pfam PF12698 ABC-2 family transporter protein 127 327 9.3E-21 T 12-10-2018 AFR_15840 7ee5b16295a72839330ae46fd239a218 159 Gene3D G3DSA:3.30.300.180 2 83 5.3E-9 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily AFR_24240 ddcdeca06bc19630a27fef732154e62d 294 Gene3D G3DSA:1.10.3720.10 76 291 5.8E-22 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24240 ddcdeca06bc19630a27fef732154e62d 294 SUPERFAMILY SSF161098 82 272 7.98E-21 T 12-10-2018 IPR035906 MetI-like superfamily AFR_24240 ddcdeca06bc19630a27fef732154e62d 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 289 6.5E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_22600 be483cf7b351dd4ed222849f4f6bf730 282 SUPERFAMILY SSF53474 26 277 1.94E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_22600 be483cf7b351dd4ed222849f4f6bf730 282 Pfam PF12697 Alpha/beta hydrolase family 53 266 1.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_22600 be483cf7b351dd4ed222849f4f6bf730 282 Gene3D G3DSA:3.40.50.1820 3 281 1.0E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_21270 fe1c73096fee11b3cd0d5264afb54059 261 PIRSF PIRSF006648 1 259 7.6E-20 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFR_21270 fe1c73096fee11b3cd0d5264afb54059 261 Pfam PF01061 ABC-2 type transporter 22 224 2.4E-18 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_37500 dbd5abc99e04b951fa4bc0567bb1bc71 261 Pfam PF11303 Protein of unknown function (DUF3105) 124 242 1.4E-39 T 12-10-2018 IPR021454 Protein of unknown function DUF3105 AFR_07375 41a2579f7e71609c2c67f8ce66db2e6e 118 Gene3D G3DSA:3.10.180.10 1 118 3.7E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_07375 41a2579f7e71609c2c67f8ce66db2e6e 118 SUPERFAMILY SSF54593 1 117 6.58E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_42655 64fc9012fab716794cecf989f1a33aef 167 Pfam PF00583 Acetyltransferase (GNAT) family 39 134 5.2E-10 T 12-10-2018 IPR000182 GNAT domain AFR_42655 64fc9012fab716794cecf989f1a33aef 167 Gene3D G3DSA:3.40.630.30 5 154 2.8E-18 T 12-10-2018 AFR_42655 64fc9012fab716794cecf989f1a33aef 167 SUPERFAMILY SSF55729 1 141 2.66E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_28255 1621cb011ca8d3315d5819d4298eb5b3 119 Pfam PF04237 YjbR 15 111 8.0E-7 T 12-10-2018 IPR007351 Uncharacterised protein YjbR AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 8.1E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 8.1E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 8.1E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.1E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.1E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 8.1E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 SUPERFAMILY SSF51735 5 243 5.71E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 Gene3D G3DSA:3.40.50.720 1 244 7.8E-73 T 12-10-2018 AFR_11655 8f0ca9c2338c558b7f267d9a8c81e4aa 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 1.5E-56 T 12-10-2018 AFR_26590 6c4eb73ef72690b33d66ef5fd5a58284 432 Pfam PF02687 FtsX-like permease family 84 172 4.0E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_09195 93776b54bf120321832b6df1d3ed42b0 207 Pfam PF06197 Protein of unknown function (DUF998) 15 198 7.2E-31 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_20520 1cbe3494a1fb196ad1bec458bb69e492 291 SUPERFAMILY SSF161098 17 274 5.51E-53 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20520 1cbe3494a1fb196ad1bec458bb69e492 291 Gene3D G3DSA:1.10.3720.10 15 280 1.6E-50 T 12-10-2018 IPR035906 MetI-like superfamily AFR_20520 1cbe3494a1fb196ad1bec458bb69e492 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 272 2.6E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_30350 85cf67d2517897c3e4d52dd06c71b5ea 234 Pfam PF02698 DUF218 domain 63 200 3.3E-22 T 12-10-2018 IPR003848 Domain of unknown function DUF218 AFR_00370 c0ebd5beee56e9c7435344f0d505d5e7 94 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 3 69 7.7E-10 T 12-10-2018 IPR009241 Toxin HigB-like AFR_08035 d16310a5a3a9f55cb5046474493dbd07 124 Pfam PF06271 RDD family 23 118 4.9E-11 T 12-10-2018 IPR010432 RDD AFR_40915 6b1a8238ad150a86cf2c883ad8c0be7e 336 Pfam PF12679 ABC-2 family transporter protein 10 266 1.9E-13 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_38425 0ef6497d8c606774bd0a88bcbfd52195 249 Gene3D G3DSA:3.20.20.370 40 249 2.7E-54 T 12-10-2018 AFR_38425 0ef6497d8c606774bd0a88bcbfd52195 249 Pfam PF01522 Polysaccharide deacetylase 56 180 3.8E-30 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFR_38425 0ef6497d8c606774bd0a88bcbfd52195 249 SUPERFAMILY SSF88713 48 243 1.16E-50 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFR_36190 6be5abd809b52eb254398b4aead351ca 354 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 6 33 6.7E-10 T 12-10-2018 IPR019933 DivIVA domain AFR_36190 6be5abd809b52eb254398b4aead351ca 354 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 44 75 6.0E-10 T 12-10-2018 IPR019933 DivIVA domain AFR_19940 2794af3ea9d8f89541d9c57b2d5d12ca 320 Pfam PF12740 Chlorophyllase enzyme 105 213 1.3E-8 T 12-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 AFR_19940 2794af3ea9d8f89541d9c57b2d5d12ca 320 SUPERFAMILY SSF53474 52 301 3.74E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_19940 2794af3ea9d8f89541d9c57b2d5d12ca 320 Gene3D G3DSA:3.40.50.1820 55 314 1.5E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_01975 04129b192bc101b9b81c417b5988c5d2 167 Pfam PF14317 YcxB-like protein 110 157 1.2E-9 T 12-10-2018 IPR025588 YcxB-like protein AFR_42160 ce3eaed7f602169a56bcec4ca173e7c3 127 Gene3D G3DSA:1.10.1660.10 32 107 3.8E-11 T 12-10-2018 AFR_42160 ce3eaed7f602169a56bcec4ca173e7c3 127 SMART SM00422 40 108 5.0E-4 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_42160 ce3eaed7f602169a56bcec4ca173e7c3 127 SUPERFAMILY SSF46955 40 119 1.01E-9 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFR_42160 ce3eaed7f602169a56bcec4ca173e7c3 127 Pfam PF13411 MerR HTH family regulatory protein 40 99 1.0E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFR_23125 b56957ef42b91add354463d56d12e87b 204 Gene3D G3DSA:3.40.109.10 12 204 4.1E-29 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_23125 b56957ef42b91add354463d56d12e87b 204 Pfam PF00881 Nitroreductase family 25 182 7.6E-20 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFR_23125 b56957ef42b91add354463d56d12e87b 204 SUPERFAMILY SSF55469 21 203 4.06E-41 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_40675 e0dad0bea2d75e23bc8d776196a28305 311 Pfam PF06089 L-asparaginase II 4 308 1.7E-116 T 12-10-2018 IPR010349 L-asparaginase II AFR_32810 841600bc8ad6a7d7b42657f8a6fc35de 545 Gene3D G3DSA:1.10.4160.10 12 471 5.7E-14 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily AFR_01400 f76c19553aed60739fe81b9a7813a86f 487 SUPERFAMILY SSF143968 323 486 3.4E-56 T 12-10-2018 AFR_01400 f76c19553aed60739fe81b9a7813a86f 487 SUPERFAMILY SSF50475 8 322 1.33E-114 T 12-10-2018 AFR_01400 f76c19553aed60739fe81b9a7813a86f 487 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 13 445 3.9E-194 T 12-10-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 AFR_01400 f76c19553aed60739fe81b9a7813a86f 487 Gene3D G3DSA:3.40.1670.10 337 452 9.1E-34 T 12-10-2018 AFR_01400 f76c19553aed60739fe81b9a7813a86f 487 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 12 453 5.1E-143 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFR_01400 f76c19553aed60739fe81b9a7813a86f 487 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 15 428 3.3E-160 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFR_24640 17ce8a19d460e4290fda01b3eed8e17e 201 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 128 186 9.3E-18 T 12-10-2018 AFR_40735 3ba607f36ebf74b7fba21435f7523ad2 262 Pfam PF11209 Protein of unknown function (DUF2993) 35 250 1.6E-27 T 12-10-2018 IPR021373 Protein of unknown function DUF2993 AFR_14995 01d1c09621ed4ed287ffffff33e75dc5 265 SUPERFAMILY SSF103032 25 255 1.7E-5 T 12-10-2018 IPR035948 YwqG-like superfamily AFR_06825 7445ff01eb8d838aa3c4f78e7689b2a8 75 Pfam PF11042 Protein of unknown function (DUF2750) 1 67 1.2E-15 T 12-10-2018 IPR021284 Protein of unknown function DUF2750 AFR_16310 e7e4a58b83f6e338f3274430024d036c 465 Pfam PF14362 Domain of unknown function (DUF4407) 11 348 7.7E-85 T 12-10-2018 IPR025519 Protein of unknown function DUF4407 AFR_11585 f2f623c792e5e8d524da428ec47feccb 218 Pfam PF11361 Protein of unknown function (DUF3159) 11 197 4.8E-57 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 AFR_06895 56071fea55dac0ea7adc0ab967c34e4f 184 Pfam PF08719 Domain of unknown function (DUF1768) 26 183 1.8E-49 T 12-10-2018 IPR012816 NADAR AFR_06895 56071fea55dac0ea7adc0ab967c34e4f 184 SUPERFAMILY SSF143990 22 183 5.89E-48 T 12-10-2018 IPR037238 YbiA-like superfamily AFR_06895 56071fea55dac0ea7adc0ab967c34e4f 184 Gene3D G3DSA:1.10.357.40 26 184 6.1E-38 T 12-10-2018 IPR037238 YbiA-like superfamily AFR_06895 56071fea55dac0ea7adc0ab967c34e4f 184 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 24 183 2.6E-48 T 12-10-2018 IPR012816 NADAR AFR_23610 44f7339b065242a70b112ab0d83b35f2 131 Pfam PF11042 Protein of unknown function (DUF2750) 25 122 1.0E-19 T 12-10-2018 IPR021284 Protein of unknown function DUF2750 AFR_12235 f73ea0c54c63bd2b077a77be1b03f02f 134 Gene3D G3DSA:3.40.50.720 1 110 9.3E-10 T 12-10-2018 AFR_27915 0e71ac71cc4125987a6898cb2f7a9f95 439 Gene3D G3DSA:3.40.710.10 57 432 1.8E-82 T 12-10-2018 AFR_27915 0e71ac71cc4125987a6898cb2f7a9f95 439 Pfam PF00144 Beta-lactamase 86 427 5.2E-64 T 12-10-2018 IPR001466 Beta-lactamase-related AFR_27915 0e71ac71cc4125987a6898cb2f7a9f95 439 SUPERFAMILY SSF56601 83 416 2.97E-77 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFR_12305 adc405bd5fc3c29f9431f3dd80c84786 390 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 15 367 2.0E-88 T 12-10-2018 IPR010640 Low temperature requirement A AFR_37195 fc568ef0f35f3fe9f41bfb6865d5ac75 387 SUPERFAMILY SSF51905 5 366 1.73E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37195 fc568ef0f35f3fe9f41bfb6865d5ac75 387 Pfam PF01494 FAD binding domain 5 340 1.1E-24 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFR_37195 fc568ef0f35f3fe9f41bfb6865d5ac75 387 Gene3D G3DSA:3.50.50.60 5 360 1.9E-74 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFR_37195 fc568ef0f35f3fe9f41bfb6865d5ac75 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 3.6E-19 T 12-10-2018 AFR_37195 fc568ef0f35f3fe9f41bfb6865d5ac75 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 3.6E-19 T 12-10-2018 AFR_37195 fc568ef0f35f3fe9f41bfb6865d5ac75 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 3.6E-19 T 12-10-2018 AFR_37195 fc568ef0f35f3fe9f41bfb6865d5ac75 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.6E-19 T 12-10-2018 AFR_09310 63b9be4289afcf257c1e02e6b1946869 286 Pfam PF06182 ABC-2 family transporter protein 80 285 1.4E-12 T 12-10-2018 IPR010390 Protein of unknown function DUF990 AFR_40240 4a0aac90e641d9d6ec1a361c38a80630 274 Pfam PF01261 Xylose isomerase-like TIM barrel 24 211 2.5E-12 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFR_40240 4a0aac90e641d9d6ec1a361c38a80630 274 Gene3D G3DSA:3.20.20.150 3 261 3.4E-37 T 12-10-2018 AFR_40240 4a0aac90e641d9d6ec1a361c38a80630 274 SUPERFAMILY SSF51658 16 265 8.12E-40 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily AFR_33565 ea7e9202f6a9e01b365094f04155eae9 263 SUPERFAMILY SSF51679 8 236 1.05E-42 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_33565 ea7e9202f6a9e01b365094f04155eae9 263 Gene3D G3DSA:3.20.20.30 6 263 4.1E-48 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_33565 ea7e9202f6a9e01b365094f04155eae9 263 Pfam PF00296 Luciferase-like monooxygenase 7 228 4.3E-39 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_18460 23a221aca86f8727cfa267eb43b92e2f 274 Pfam PF09335 SNARE associated Golgi protein 54 181 2.0E-23 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFR_06015 41e08b19f98b353f47043ec046de6a8e 318 Gene3D G3DSA:2.130.10.10 4 298 2.2E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFR_06015 41e08b19f98b353f47043ec046de6a8e 318 SUPERFAMILY SSF50969 25 213 4.55E-5 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFR_23080 c35adfd3946a26b5f4290b64ade8c958 199 Gene3D G3DSA:1.10.357.10 1 194 2.9E-14 T 12-10-2018 AFR_23080 c35adfd3946a26b5f4290b64ade8c958 199 SUPERFAMILY SSF46689 5 76 2.67E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_27115 721bc24941622ac220d72a9f9dc1e926 130 SUPERFAMILY SSF55729 3 119 7.48E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_27115 721bc24941622ac220d72a9f9dc1e926 130 Gene3D G3DSA:3.40.630.30 3 125 3.8E-31 T 12-10-2018 AFR_27115 721bc24941622ac220d72a9f9dc1e926 130 Pfam PF00583 Acetyltransferase (GNAT) family 30 115 2.0E-17 T 12-10-2018 IPR000182 GNAT domain AFR_12150 a5cfe27ff3e12ca84627fbde28b52851 398 Pfam PF10935 Protein of unknown function (DUF2637) 13 118 6.1E-11 T 12-10-2018 IPR021235 Protein of unknown function DUF2637 AFR_32770 f0bdd60ec0eb59b91659ee63576d5b5c 366 Pfam PF00296 Luciferase-like monooxygenase 7 330 6.5E-76 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFR_32770 f0bdd60ec0eb59b91659ee63576d5b5c 366 Gene3D G3DSA:3.20.20.30 5 363 9.6E-101 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_32770 f0bdd60ec0eb59b91659ee63576d5b5c 366 SUPERFAMILY SSF51679 1 356 2.22E-77 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFR_21900 ffd2cb0d670e63fd6ef1b2faa9b4785d 157 Pfam PF08592 Domain of unknown function (DUF1772) 21 153 5.0E-13 T 12-10-2018 AFR_40480 ce4256895979535f1f338443eb8608e5 95 Pfam PF06289 Flagellar protein (FlbD) 2 57 4.0E-22 T 12-10-2018 IPR009384 Swarming motility protein SwrD-like AFR_36960 20a067d9c7f28ee3bbb31e1b36cc5751 392 Gene3D G3DSA:2.120.10.30 46 384 1.5E-106 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFR_36960 20a067d9c7f28ee3bbb31e1b36cc5751 392 SUPERFAMILY SSF50952 64 381 4.97E-45 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFR_36960 20a067d9c7f28ee3bbb31e1b36cc5751 392 Pfam PF07995 Glucose / Sorbosone dehydrogenase 72 367 7.7E-62 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFR_36460 0522767ab01a8566e5dbde06039c5864 155 Gene3D G3DSA:2.80.10.50 13 143 3.1E-5 T 12-10-2018 AFR_37395 09d6d945cae75efc6291b0af4b29ceb9 209 SMART SM00226 5 200 5.1E-10 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFR_37395 09d6d945cae75efc6291b0af4b29ceb9 209 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 128 8.5E-16 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFR_37395 09d6d945cae75efc6291b0af4b29ceb9 209 SUPERFAMILY SSF52788 2 201 2.35E-28 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFR_40970 989af7b01c744578dfeffd6760595410 192 Pfam PF03713 Domain of unknown function (DUF305) 44 189 5.5E-37 T 12-10-2018 IPR005183 Domain of unknown function DUF305 AFR_40970 989af7b01c744578dfeffd6760595410 192 Gene3D G3DSA:1.20.1260.10 33 192 4.3E-40 T 12-10-2018 IPR012347 Ferritin-like AFR_22455 5af5d862ef1770fe5f3ef4832395fc5a 150 Gene3D G3DSA:3.10.180.10 4 150 6.6E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_22455 5af5d862ef1770fe5f3ef4832395fc5a 150 SUPERFAMILY SSF54593 8 148 3.54E-9 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_28940 730d2f7a8a373953d34707d057130083 484 SUPERFAMILY SSF53474 92 451 1.39E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28940 730d2f7a8a373953d34707d057130083 484 Pfam PF00561 alpha/beta hydrolase fold 79 450 6.7E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_27910 e6aec6299ab05e0493fad33229d43ffb 245 Pfam PF13578 Methyltransferase domain 66 206 7.9E-7 T 12-10-2018 AFR_27910 e6aec6299ab05e0493fad33229d43ffb 245 Gene3D G3DSA:3.40.50.150 4 245 7.1E-73 T 12-10-2018 AFR_27910 e6aec6299ab05e0493fad33229d43ffb 245 SUPERFAMILY SSF53335 29 213 3.49E-5 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_29590 6d3e5ed2b029bc76b61964e4dbbdf2c8 1242 Pfam PF04465 Protein of unknown function (DUF499) 352 443 4.1E-5 T 12-10-2018 IPR007555 Protein of unknown function DUF499 AFR_23940 cb32f6370da2b31e6aabdc9d27da27c3 328 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 8 315 2.3E-104 T 12-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 AFR_23940 cb32f6370da2b31e6aabdc9d27da27c3 328 Pfam PF03741 Integral membrane protein TerC family 71 278 1.9E-46 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFR_39335 a7c857b6767df084bbdc1182a56d0b89 246 Pfam PF13398 Peptidase M50B-like 27 229 6.2E-62 T 12-10-2018 AFR_38870 ac04d3528530f00d2f87685f7eeeaade 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 4.8E-28 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_15985 0bb48eed2821c0fee87e3f5c5424e6ee 454 Pfam PF04932 O-Antigen ligase 239 368 3.8E-8 T 12-10-2018 IPR007016 O-antigen ligase-related AFR_07480 e4669132df424d8fa5de7fc753a4bf12 396 Pfam PF06245 Protein of unknown function (DUF1015) 19 393 1.2E-49 T 12-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 AFR_20465 4ca7ea332df33698029394c3fe1e82d2 198 PIRSF PIRSF006324 1 198 1.4E-51 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_20465 4ca7ea332df33698029394c3fe1e82d2 198 Pfam PF01810 LysE type translocator 11 197 1.6E-33 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFR_32260 6003b9f78458896b25d4aa7419db0339 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 142 9.1E-36 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_32260 6003b9f78458896b25d4aa7419db0339 146 Pfam PF04075 F420H(2)-dependent quinone reductase 14 142 8.3E-50 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 AFR_32260 6003b9f78458896b25d4aa7419db0339 146 Gene3D G3DSA:2.30.110.10 1 143 7.5E-57 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_25075 b0f1ea71430cd08ed9292fe43aeb8e36 323 Pfam PF02517 CAAX protease self-immunity 159 247 5.0E-14 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFR_18050 11c459e46aff1cca21468829d03e7bbd 186 SUPERFAMILY SSF53597 1 185 2.24E-26 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_18050 11c459e46aff1cca21468829d03e7bbd 186 Pfam PF01872 RibD C-terminal domain 4 181 6.4E-23 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_18050 11c459e46aff1cca21468829d03e7bbd 186 Gene3D G3DSA:3.40.430.10 2 184 6.2E-38 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_41425 d6c3dcf06aa23dc132d98fe24c6b4262 238 Gene3D G3DSA:1.10.3720.10 22 218 1.1E-29 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41425 d6c3dcf06aa23dc132d98fe24c6b4262 238 SUPERFAMILY SSF161098 21 208 9.42E-32 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41425 d6c3dcf06aa23dc132d98fe24c6b4262 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 215 9.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_34875 81923653e1beea3b4fbd68af9a73f155 262 Pfam PF13628 Domain of unknown function (DUF4142) 59 192 5.6E-16 T 12-10-2018 IPR025419 Domain of unknown function DUF4142 AFR_32615 024036ebf70ace510aa4484fa850a417 143 Gene3D G3DSA:2.30.31.20 3 141 6.7E-48 T 12-10-2018 IPR038658 Sporulation-specific cell division protein SsgB superfamily AFR_32615 024036ebf70ace510aa4484fa850a417 143 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 27 126 1.5E-35 T 12-10-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 AFR_40335 4664cf65ba45f8ccaabd0a97dcd5c6e4 133 SMART SM00448 9 122 2.7E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40335 4664cf65ba45f8ccaabd0a97dcd5c6e4 133 Pfam PF00072 Response regulator receiver domain 11 122 1.9E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFR_40335 4664cf65ba45f8ccaabd0a97dcd5c6e4 133 Gene3D G3DSA:3.40.50.2300 2 132 3.0E-23 T 12-10-2018 AFR_40335 4664cf65ba45f8ccaabd0a97dcd5c6e4 133 SUPERFAMILY SSF52172 9 129 3.84E-25 T 12-10-2018 IPR011006 CheY-like superfamily AFR_34040 287c6a1dc7d2b40eddfaf9cc5c0a3428 319 Gene3D G3DSA:2.160.20.100 182 306 2.7E-5 T 12-10-2018 AFR_06125 fb51d1155da7645b7910477a46635261 335 Pfam PF14350 Beta protein 6 330 6.0E-75 T 12-10-2018 IPR025683 Protein beta AFR_35120 d510c8ec66f25e63f721bad3198b0cd3 157 Pfam PF10756 Bacterial PH domain 69 121 1.4E-5 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 AFR_05485 8c265a354678e890b22a9051522d0045 217 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 13 172 3.6E-11 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system AFR_02595 27218f1aa3f23b6110eb80a77705ec78 979 Gene3D G3DSA:3.90.176.10 716 929 1.6E-33 T 12-10-2018 AFR_02465 0716186e0c2b536d2110f77e396b0353 107 Pfam PF15567 Immunity protein 35 6 87 1.3E-26 T 12-10-2018 IPR029082 Immunity protein 35 AFR_00240 b3553dc506953bc92d797a997eedecc3 74 Pfam PF04149 Domain of unknown function (DUF397) 15 68 1.2E-25 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_07980 de57655ca40d82d9e2d0c3c2e2dc827a 351 Pfam PF01757 Acyltransferase family 4 311 9.8E-23 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_03670 f6a1ab4534b3c586f45dab20dc5ca1f5 284 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 247 279 7.3E-4 T 12-10-2018 AFR_15135 58c69cff79fa9610799fada2e2d5b550 248 Pfam PF12730 ABC-2 family transporter protein 3 147 4.1E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_17200 0a5b6155d5f875a8be525e85c2857766 132 Pfam PF10825 Protein of unknown function (DUF2752) 37 83 1.3E-15 T 12-10-2018 IPR021215 Protein of unknown function DUF2752 AFR_23880 1f84e63ca59a2f72a69dea5f46485f3f 340 SUPERFAMILY SSF103032 17 287 2.88E-5 T 12-10-2018 IPR035948 YwqG-like superfamily AFR_00255 738a3a96604fe4fcf4d6df2e80f3c85a 273 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 64 241 1.5E-41 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 AFR_00255 738a3a96604fe4fcf4d6df2e80f3c85a 273 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 68 237 4.4E-51 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 AFR_18855 e1a55c392b0858883d1f8c72d99b8380 285 SUPERFAMILY SSF55729 23 173 1.47E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_18855 e1a55c392b0858883d1f8c72d99b8380 285 Gene3D G3DSA:3.40.630.30 21 176 6.9E-7 T 12-10-2018 AFR_32435 4f4a5b50f6be9fc7eec78b7413529d1f 260 Pfam PF03734 L,D-transpeptidase catalytic domain 82 246 5.7E-8 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFR_23900 4b8c57594677671853208e544a0c1d3a 213 Pfam PF06197 Protein of unknown function (DUF998) 4 195 8.8E-21 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_02315 d9803a2bf8af19d1e2fffaf83775665e 201 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 19 200 1.3E-27 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 AFR_02315 d9803a2bf8af19d1e2fffaf83775665e 201 Pfam PF04973 Nicotinamide mononucleotide transporter 18 196 9.0E-53 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 AFR_19530 bc08a1733f2a1a07ee76bcad26c3f2b7 253 Pfam PF02361 Cobalt transport protein 14 218 2.5E-31 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AFR_19530 bc08a1733f2a1a07ee76bcad26c3f2b7 253 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 20 214 2.7E-39 T 12-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 AFR_04360 2536899c20ceb3ed4b8cc6844b74d2bd 192 SUPERFAMILY SSF53597 3 191 9.26E-23 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_04360 2536899c20ceb3ed4b8cc6844b74d2bd 192 Pfam PF01872 RibD C-terminal domain 4 184 7.3E-24 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_04360 2536899c20ceb3ed4b8cc6844b74d2bd 192 Gene3D G3DSA:3.40.430.10 1 190 7.0E-34 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_18985 d72768ef2eed69f728a544adcac050e7 184 Gene3D G3DSA:1.10.357.10 1 183 1.9E-28 T 12-10-2018 AFR_18985 d72768ef2eed69f728a544adcac050e7 184 SUPERFAMILY SSF46689 1 62 1.95E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFR_18985 d72768ef2eed69f728a544adcac050e7 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 44 6.3E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFR_11545 d9d5fc30631d9e60af6addbd4f6b4653 332 Gene3D G3DSA:2.40.420.20 235 310 1.8E-9 T 12-10-2018 AFR_32280 6fcc343608474fc26346541e8782fbbe 343 SUPERFAMILY SSF81345 15 335 4.84E-66 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_32280 6fcc343608474fc26346541e8782fbbe 343 Gene3D G3DSA:1.10.3470.10 18 341 2.4E-84 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFR_32280 6fcc343608474fc26346541e8782fbbe 343 Pfam PF01032 FecCD transport family 32 335 7.2E-78 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFR_40710 8db6f98734b28e0f829514ab91e5588e 45 SUPERFAMILY SSF88946 4 44 2.86E-7 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFR_40710 8db6f98734b28e0f829514ab91e5588e 45 Pfam PF04542 Sigma-70 region 2 12 43 1.1E-4 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFR_08525 94672cd1e66c6d5e3f0c1c4b58a7a913 210 Gene3D G3DSA:3.40.109.10 9 210 2.1E-32 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_08525 94672cd1e66c6d5e3f0c1c4b58a7a913 210 SUPERFAMILY SSF55469 9 209 9.29E-28 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFR_08525 94672cd1e66c6d5e3f0c1c4b58a7a913 210 Pfam PF00881 Nitroreductase family 17 179 6.3E-22 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFR_04890 0e756951d0f6c7533f0f48b517c1ae2a 418 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 401 3.4E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_06575 65466dc6dd713e73326bed67fe659894 141 Pfam PF11750 Protein of unknown function (DUF3307) 15 137 1.1E-7 T 12-10-2018 IPR021737 Bacteriophage phiKZ, Orf197 AFR_03890 0b4e32c71d25d167cb750e9f31ee03eb 203 Pfam PF13302 Acetyltransferase (GNAT) domain 19 155 5.7E-23 T 12-10-2018 IPR000182 GNAT domain AFR_03890 0b4e32c71d25d167cb750e9f31ee03eb 203 Gene3D G3DSA:3.40.630.30 3 174 1.3E-34 T 12-10-2018 AFR_03890 0b4e32c71d25d167cb750e9f31ee03eb 203 SUPERFAMILY SSF55729 8 160 1.75E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_09955 120938ae1b3fa53b6c949905f9a6b768 238 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 8 199 4.3E-33 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFR_09955 120938ae1b3fa53b6c949905f9a6b768 238 Gene3D G3DSA:3.40.50.880 25 208 1.1E-8 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_09955 120938ae1b3fa53b6c949905f9a6b768 238 SUPERFAMILY SSF52317 31 212 1.67E-19 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFR_38840 5fc6ca07f12926829586fe9c59e646d7 380 Pfam PF13367 Protease prsW family 82 276 5.4E-37 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 AFR_18750 53e704d5c543b0fbfef7f186e56d6357 294 SUPERFAMILY SSF47240 51 237 8.85E-10 T 12-10-2018 IPR009078 Ferritin-like superfamily AFR_18750 53e704d5c543b0fbfef7f186e56d6357 294 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 4 277 5.5E-100 T 12-10-2018 IPR025859 P-aminobenzoate N-oxygenase AurF AFR_12160 1816075f7d63983e02746eb7238756cc 129 Pfam PF13586 Transposase DDE domain 26 121 4.6E-19 T 12-10-2018 IPR025668 Transposase DDE domain AFR_09175 f5fee2dd829f779232e89fa3dd0246f4 112 Pfam PF14206 Cysteine-rich CPCC 33 108 1.9E-30 T 12-10-2018 IPR025983 Cysteine-rich CPCC domain AFR_10910 53724a055f457ef932ff782808c2fb78 81 Pfam PF10944 Protein of unknown function (DUF2630) 2 81 1.0E-34 T 12-10-2018 IPR020311 Uncharacterised protein family, Rv0898c AFR_10910 53724a055f457ef932ff782808c2fb78 81 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 1 81 4.0E-20 T 12-10-2018 IPR020311 Uncharacterised protein family, Rv0898c AFR_19725 faa1b9106eab6aac48854d93690730d9 352 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 297 1.1E-31 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFR_01700 1e5fe7a96503215223b2db3aba5b3cce 255 Gene3D G3DSA:1.20.120.1200 20 179 6.0E-43 T 12-10-2018 AFR_01700 1e5fe7a96503215223b2db3aba5b3cce 255 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 30 176 2.1E-33 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFR_24545 bdbd7b1527d34593943bfc79e6027943 334 Pfam PF03773 Predicted permease 54 326 5.8E-51 T 12-10-2018 IPR005524 Predicted permease DUF318 AFR_33780 2691ef1bd34cdc1d7b1caa6625689aff 224 Pfam PF07103 Protein of unknown function (DUF1365) 6 221 3.9E-60 T 12-10-2018 IPR010775 Protein of unknown function DUF1365 AFR_05165 d3418b63a9861765d0cf5c2a96ef9a30 261 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 64 241 7.0E-53 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 AFR_05165 d3418b63a9861765d0cf5c2a96ef9a30 261 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 61 241 6.2E-35 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 AFR_06975 cf334116bd7ad72b3e9aa7cf882d3ebf 128 Pfam PF05331 Protein of unknown function (DUF742) 17 128 4.0E-29 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_05745 6603a7b5eb53195f4946c416d75bc762 60 Pfam PF04149 Domain of unknown function (DUF397) 2 53 1.3E-20 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_17590 fbd072e214404407f01ed89b43a940a3 623 Pfam PF02538 Hydantoinase B/oxoprolinase 18 537 6.6E-136 T 12-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFR_27505 ccefdabc8ef2f0f8c03a29ef0af81929 138 Pfam PF08818 Domain of unknown function (DU1801) 25 127 1.7E-11 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 AFR_13305 5a40c0b332e089b221cc4954f8761003 106 Pfam PF05154 TM2 domain 27 75 3.0E-15 T 12-10-2018 IPR007829 TM2 domain AFR_12155 38b3f5d9a7a587ccdfdb156d5583dce0 66 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 62 5.8E-22 T 12-10-2018 IPR025161 Putative transposase IS4/IS5 family AFR_03685 1a3e2f36ed736a943c83324a895b2434 1025 SUPERFAMILY SSF69318 729 1020 1.83E-18 T 12-10-2018 AFR_12685 5905de12f1ce9666bf2906f136cb707c 118 Pfam PF14330 Domain of unknown function (DUF4387) 11 103 1.2E-28 T 12-10-2018 IPR025496 Protein of unknown function DUF4387 AFR_36430 da67505372a1630b2d88ca2920f388f0 265 Gene3D G3DSA:3.90.1200.10 121 165 4.6E-9 T 12-10-2018 AFR_36430 da67505372a1630b2d88ca2920f388f0 265 SUPERFAMILY SSF56112 29 237 4.99E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFR_36430 da67505372a1630b2d88ca2920f388f0 265 Pfam PF01636 Phosphotransferase enzyme family 37 173 1.6E-14 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFR_02015 9baad081ca616e8015949a533b48fc3c 67 Pfam PF04149 Domain of unknown function (DUF397) 11 60 2.7E-20 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_18740 5f6a038282c82af603259a2c393a81c5 98 Pfam PF16170 Domain of unknown function (DUF4873) 4 93 2.3E-29 T 12-10-2018 IPR032371 Domain of unknown function DUF4873 AFR_16870 5382b6de5e2928db3c601c478f0255b4 284 Gene3D G3DSA:3.40.50.150 62 252 1.4E-37 T 12-10-2018 AFR_16870 5382b6de5e2928db3c601c478f0255b4 284 SUPERFAMILY SSF53335 65 252 1.29E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFR_16870 5382b6de5e2928db3c601c478f0255b4 284 Pfam PF08241 Methyltransferase domain 100 190 1.7E-24 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFR_27535 71ef6936709781d1c41cad59f64f74cc 403 Pfam PF01384 Phosphate transporter family 17 337 1.3E-80 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 AFR_03030 bb394964cd2a3e4bbe1e92da7cbea0a2 260 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 36 82 2.5E-13 T 12-10-2018 IPR027805 Transposase, Helix-turn-helix domain AFR_03030 bb394964cd2a3e4bbe1e92da7cbea0a2 260 Pfam PF13359 DDE superfamily endonuclease 102 251 1.4E-30 T 12-10-2018 IPR027806 Harbinger transposase-derived nuclease domain AFR_39670 2643852280f39dfcd4ac3cdb54fcbf4c 316 SUPERFAMILY SSF161098 74 305 7.46E-58 T 12-10-2018 IPR035906 MetI-like superfamily AFR_39670 2643852280f39dfcd4ac3cdb54fcbf4c 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 309 4.8E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFR_39670 2643852280f39dfcd4ac3cdb54fcbf4c 316 Gene3D G3DSA:1.10.3720.10 70 315 8.7E-66 T 12-10-2018 IPR035906 MetI-like superfamily AFR_41125 bdbb9683a0c201ec140c41521f71f67f 703 Gene3D G3DSA:2.60.40.10 261 329 3.4E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFR_09160 123d59938855b1e1f9dc79d3f547e19b 532 Pfam PF03235 Protein of unknown function DUF262 16 217 1.3E-27 T 12-10-2018 IPR004919 Domain of unknown function DUF262 AFR_00150 b08c8b0a42c440cc85b138fa4a8da9ab 177 Pfam PF04892 VanZ like family 56 158 1.1E-14 T 12-10-2018 IPR006976 VanZ-like AFR_31735 3cd64086219eb41f71a9e84cce90d73f 443 Pfam PF00561 alpha/beta hydrolase fold 38 406 1.1E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_31735 3cd64086219eb41f71a9e84cce90d73f 443 SUPERFAMILY SSF53474 33 416 5.36E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_17775 04b27bddf04f5773f7ddb400278e3272 191 Pfam PF01872 RibD C-terminal domain 4 185 9.2E-17 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFR_17775 04b27bddf04f5773f7ddb400278e3272 191 Gene3D G3DSA:3.40.430.10 1 190 1.2E-32 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_17775 04b27bddf04f5773f7ddb400278e3272 191 SUPERFAMILY SSF53597 4 190 7.07E-22 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFR_37275 f683bf798f733445e49914669dca304f 877 Gene3D G3DSA:3.40.50.300 340 625 7.2E-50 T 12-10-2018 AFR_37275 f683bf798f733445e49914669dca304f 877 Pfam PF01580 FtsK/SpoIIIE family 376 542 9.8E-15 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFR_37275 f683bf798f733445e49914669dca304f 877 Gene3D G3DSA:3.40.50.300 104 284 3.5E-10 T 12-10-2018 AFR_37275 f683bf798f733445e49914669dca304f 877 SUPERFAMILY SSF52540 333 569 5.6E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_38670 de556966b81e6e1af5b53f0384bb6648 252 SUPERFAMILY SSF52266 7 239 9.62E-18 T 12-10-2018 AFR_06935 111bc95aced015a6107069d3edf65dd8 754 Pfam PF01435 Peptidase family M48 49 220 6.8E-8 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFR_24105 cc5da5d76888de83b1567aa11334be4b 119 SUPERFAMILY SSF52309 2 107 2.61E-5 T 12-10-2018 AFR_35695 8f778680d11b990695e62aed720212e0 161 Pfam PF07681 DoxX 12 90 3.5E-9 T 12-10-2018 IPR032808 DoxX family AFR_21990 90d1bd798e0669caf698a3c878e7f5d9 149 Pfam PF14325 Domain of unknown function (DUF4383) 17 140 1.2E-46 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 AFR_39395 2b89dd7809e24add0ae6975a2af9fc9a 147 Pfam PF13564 DoxX-like family 32 110 7.2E-8 T 12-10-2018 IPR032808 DoxX family AFR_24145 356f08982503fa42f3a53f29a040fc4e 71 Pfam PF04149 Domain of unknown function (DUF397) 9 63 1.8E-24 T 12-10-2018 IPR007278 Domain of unknown function DUF397 AFR_11815 d8269dfde051854801bc56cec6dcd382 137 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 131 1.9E-13 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFR_11815 d8269dfde051854801bc56cec6dcd382 137 Gene3D G3DSA:3.30.530.20 1 133 5.3E-23 T 12-10-2018 IPR023393 START-like domain superfamily AFR_11815 d8269dfde051854801bc56cec6dcd382 137 SUPERFAMILY SSF55961 1 132 5.5E-22 T 12-10-2018 AFR_26490 fa68a47e9cb502cb3049501ea180e8fe 247 Pfam PF09844 Uncharacterized conserved protein (COG2071) 21 233 3.5E-67 T 12-10-2018 IPR018644 Protein of unknown function DUF2071 AFR_26490 fa68a47e9cb502cb3049501ea180e8fe 247 SUPERFAMILY SSF160104 11 164 6.28E-10 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFR_40050 86256116637173835e7195e7e09f9580 177 Pfam PF06210 Protein of unknown function (DUF1003) 42 144 3.6E-40 T 12-10-2018 IPR010406 Protein of unknown function DUF1003 AFR_41855 af18fdcbab596efbad4380a11e4109a2 157 Pfam PF00582 Universal stress protein family 16 136 1.0E-9 T 12-10-2018 IPR006016 UspA AFR_41855 af18fdcbab596efbad4380a11e4109a2 157 Gene3D G3DSA:3.40.50.12370 9 148 1.2E-14 T 12-10-2018 AFR_41855 af18fdcbab596efbad4380a11e4109a2 157 SUPERFAMILY SSF52402 16 138 2.26E-11 T 12-10-2018 AFR_41955 fd911b582a7301e268672810879f7388 155 Pfam PF05331 Protein of unknown function (DUF742) 48 153 5.1E-25 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_30190 38acaa6385dc15ff1da2a860f1124322 301 Pfam PF01925 Sulfite exporter TauE/SafE 5 253 1.3E-45 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFR_15150 3517ad30a28b93ded57bf1d39115fa04 115 Pfam PF10012 Uncharacterized protein conserved in bacteria (DUF2255) 8 114 2.1E-29 T 12-10-2018 IPR016888 Uncharacterised conserved protein UCP028498 AFR_11320 a10560d5706c59fc3f674ef9aeb2b94d 260 SUPERFAMILY SSF141571 5 161 2.98E-9 T 12-10-2018 AFR_37580 c382a322f9dd956e17bf29c22a0f5b24 445 Pfam PF00067 Cytochrome P450 264 371 4.6E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_37580 c382a322f9dd956e17bf29c22a0f5b24 445 SUPERFAMILY SSF48264 119 374 1.96E-21 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_37580 c382a322f9dd956e17bf29c22a0f5b24 445 Gene3D G3DSA:1.10.630.10 50 389 1.6E-21 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFR_41455 ca487487076f2b9b8da6a9dc5b4fbeaa 172 Pfam PF11377 Protein of unknown function (DUF3180) 22 155 1.0E-39 T 12-10-2018 IPR021517 Protein of unknown function DUF3180 AFR_10400 b0655b4f210ab8fe746d2dc329926c1e 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 313 4.6E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_30730 55257e7b2be829f9b2df5529f6670b1f 739 SUPERFAMILY SSF141571 298 365 1.09E-5 T 12-10-2018 AFR_41155 9c98a45d4ade2fe18f215b362a984333 218 Pfam PF06271 RDD family 56 210 3.9E-22 T 12-10-2018 IPR010432 RDD AFR_34360 43de312fe76ad097d67cbc5640a45e2b 221 Pfam PF00857 Isochorismatase family 18 210 2.5E-45 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFR_34360 43de312fe76ad097d67cbc5640a45e2b 221 Gene3D G3DSA:3.40.50.850 12 220 1.2E-55 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_34360 43de312fe76ad097d67cbc5640a45e2b 221 SUPERFAMILY SSF52499 6 212 9.68E-56 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFR_21185 30ad1bf1025b0e8fd25a249c58f05bb8 224 Pfam PF10127 Predicted nucleotidyltransferase 8 216 1.8E-39 T 12-10-2018 IPR018775 Nucleotidyltransferase, predicted AFR_25155 03f1ee8d4713ee09bd5bfdcd74d486d3 272 Pfam PF13628 Domain of unknown function (DUF4142) 57 189 1.2E-23 T 12-10-2018 IPR025419 Domain of unknown function DUF4142 AFR_28935 1db7ae650376040b514d80915ae329a4 341 Pfam PF02517 CAAX protease self-immunity 148 242 3.5E-9 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFR_04965 a6d991485e025a8a187592caa8e0942d 364 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 86 268 3.0E-28 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFR_04965 a6d991485e025a8a187592caa8e0942d 364 Gene3D G3DSA:1.10.260.150 60 337 2.8E-50 T 12-10-2018 AFR_18990 ddb6bef8847d37d3b2b29d7dd919c530 180 SUPERFAMILY SSF109854 4 170 6.11E-34 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_18990 ddb6bef8847d37d3b2b29d7dd919c530 180 Pfam PF04978 Protein of unknown function (DUF664) 18 171 2.0E-31 T 12-10-2018 IPR007061 Protein of unknown function DUF664 AFR_18990 ddb6bef8847d37d3b2b29d7dd919c530 180 Gene3D G3DSA:1.20.120.450 2 171 2.3E-32 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFR_28695 9e0fa83a37057c7d9819e67225f543f7 81 SUPERFAMILY SSF56300 13 79 3.35E-7 T 12-10-2018 AFR_30045 5100fb02050c236637e1e031f5a60b8e 271 Pfam PF00188 Cysteine-rich secretory protein family 140 269 1.5E-9 T 12-10-2018 IPR014044 CAP domain AFR_30045 5100fb02050c236637e1e031f5a60b8e 271 Gene3D G3DSA:3.40.33.10 71 270 1.9E-32 T 12-10-2018 IPR035940 CAP superfamily AFR_30045 5100fb02050c236637e1e031f5a60b8e 271 SUPERFAMILY SSF55797 134 269 7.85E-14 T 12-10-2018 IPR035940 CAP superfamily AFR_37130 51a8a31637c5f77a2b83477bec2a824e 263 Pfam PF12697 Alpha/beta hydrolase family 22 251 3.6E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_37130 51a8a31637c5f77a2b83477bec2a824e 263 SUPERFAMILY SSF53474 3 258 2.3E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_37130 51a8a31637c5f77a2b83477bec2a824e 263 Gene3D G3DSA:3.40.50.1820 1 257 1.1E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_33320 2ef4811c67b71c3647cdc1ed37bca461 300 SUPERFAMILY SSF48239 39 292 1.57E-9 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFR_11360 f0c840133fe9e314963d36201b1a9a2d 871 SUPERFAMILY SSF48208 407 868 2.3E-41 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFR_22320 71301ed60af07f691f5b9226bcc45f6e 144 Pfam PF05360 yiaA/B two helix domain 74 126 2.7E-19 T 12-10-2018 IPR008024 YiaAB two helix AFR_22320 71301ed60af07f691f5b9226bcc45f6e 144 Pfam PF05360 yiaA/B two helix domain 11 63 1.0E-19 T 12-10-2018 IPR008024 YiaAB two helix AFR_40080 e0b18153ded70554635c3873c5141ed2 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 52 4.4E-29 T 12-10-2018 IPR021465 Protein of unknown function DUF3117 AFR_15385 6451b407f6b859680b9a9c52bf35d387 309 Pfam PF04087 Domain of unknown function (DUF389) 145 288 4.2E-24 T 12-10-2018 IPR005240 Protein of unknown function DUF389 AFR_03625 e6019b18b09fe4790570648bee5d4a14 358 SUPERFAMILY SSF56059 113 344 9.09E-12 T 12-10-2018 AFR_26265 40a1e981e3f885c9b8a7a443be356fff 150 Pfam PF08044 Domain of unknown function (DUF1707) 5 56 2.8E-11 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 AFR_08940 4c09106bb24d5d03bd57f2c97a324607 159 Pfam PF06803 Protein of unknown function (DUF1232) 88 122 3.8E-12 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 AFR_17205 d99f64fb60aaff4b594513fd90aa526e 455 Pfam PF01594 AI-2E family transporter 69 393 3.2E-66 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFR_25960 bed88dd69796fd199e5bad8d34b3015b 278 Pfam PF00795 Carbon-nitrogen hydrolase 9 253 5.4E-35 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFR_25960 bed88dd69796fd199e5bad8d34b3015b 278 SUPERFAMILY SSF56317 2 274 7.33E-55 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_25960 bed88dd69796fd199e5bad8d34b3015b 278 Gene3D G3DSA:3.60.110.10 1 277 2.6E-58 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFR_18275 d1e5441ef0bd7fc0a020e351105e20f3 77 Pfam PF17032 zinc-ribbon family 19 71 6.1E-11 T 12-10-2018 IPR031493 Zinc-ribbon 15 AFR_04820 10f48df36508767b4df10db89afa0095 92 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 89 4.7E-8 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 AFR_30300 a3fb956dc73189efc364ce169592ac3b 261 Pfam PF12730 ABC-2 family transporter protein 11 140 1.8E-6 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_08665 d65bbdf6827ca6049099ab8ad3dd596e 163 Pfam PF11343 Protein of unknown function (DUF3145) 6 161 9.9E-69 T 12-10-2018 IPR021491 Protein of unknown function DUF3145 AFR_01825 cd265286de0c09ea4f2436fb24a6177e 159 Pfam PF10756 Bacterial PH domain 67 149 6.1E-9 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 AFR_30770 643fd3d83e833daa72e1e2cdfde03f55 341 Pfam PF14027 Protein of unknown function (DUF4243) 23 314 9.0E-22 T 12-10-2018 IPR025337 Questin oxidase-like GO:0016491 AFR_21515 50205fb43a77617710e7e354cc04d687 129 SUPERFAMILY SSF54593 3 119 9.44E-12 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_21515 50205fb43a77617710e7e354cc04d687 129 Gene3D G3DSA:3.10.180.10 4 126 1.1E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_12080 c9b7cdd88890c15bdfc00feff9a14753 331 SMART SM00382 51 246 2.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFR_12080 c9b7cdd88890c15bdfc00feff9a14753 331 Pfam PF07728 AAA domain (dynein-related subfamily) 54 235 7.6E-14 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFR_12080 c9b7cdd88890c15bdfc00feff9a14753 331 SUPERFAMILY SSF52540 40 273 2.1E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_04285 f192b531d8345496d8c55f9f3da53c2c 420 Gene3D G3DSA:1.20.1250.20 17 397 1.1E-22 T 12-10-2018 AFR_04285 f192b531d8345496d8c55f9f3da53c2c 420 SUPERFAMILY SSF103473 17 397 1.57E-26 T 12-10-2018 IPR036259 MFS transporter superfamily AFR_04285 f192b531d8345496d8c55f9f3da53c2c 420 Pfam PF07690 Major Facilitator Superfamily 19 311 2.0E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFR_09340 1d1231fc1812215cf57177f3b2335a84 211 Pfam PF11241 Protein of unknown function (DUF3043) 43 209 5.7E-52 T 12-10-2018 IPR021403 Protein of unknown function DUF3043 AFR_09635 ab5b7ef72bf3f0028f2371dfa526eb57 221 Pfam PF04250 Protein of unknown function (DUF429) 3 211 2.7E-44 T 12-10-2018 IPR007362 Protein of unknown function DUF429 AFR_00460 713a6178f00ed04b8d4dfa6faa7eec99 225 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 19 222 8.8E-58 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 AFR_00460 713a6178f00ed04b8d4dfa6faa7eec99 225 Pfam PF03006 Haemolysin-III related 16 215 1.1E-39 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 AFR_03380 823c48f937fd0f422d45df7c3d81077c 370 Pfam PF01435 Peptidase family M48 75 267 2.2E-22 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFR_03380 823c48f937fd0f422d45df7c3d81077c 370 Gene3D G3DSA:3.30.2010.10 67 154 2.8E-13 T 12-10-2018 AFR_38245 afeb569f99e1dfd7797ff510c10f11ef 499 Pfam PF08811 Protein of unknown function (DUF1800) 39 497 1.9E-117 T 12-10-2018 IPR014917 Protein of unknown function DUF1800 AFR_35500 8d43385a4ec80607650b51020078b98c 258 SUPERFAMILY SSF52038 165 246 2.22E-12 T 12-10-2018 IPR035905 Barstar-like superfamily AFR_35500 8d43385a4ec80607650b51020078b98c 258 Pfam PF01337 Barstar (barnase inhibitor) 167 230 2.6E-10 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) AFR_01340 1a8d5927ef9976f35781e91aa4a24a17 539 Pfam PF05140 ResB-like family 36 526 8.3E-127 T 12-10-2018 IPR007816 ResB-like domain AFR_29920 dc9272f2c27daf4b3f01843ae9625dcd 309 Pfam PF11382 Copper transport outer membrane protein, MctB 2 305 6.5E-84 T 12-10-2018 IPR021522 Copper transporter MctB GO:0016020|GO:0055070 AFR_21565 46dc00979d67650a8b389c18f561be43 172 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 17 91 5.7E-7 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFR_21565 46dc00979d67650a8b389c18f561be43 172 Gene3D G3DSA:2.30.110.10 12 140 2.0E-18 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFR_21565 46dc00979d67650a8b389c18f561be43 172 SUPERFAMILY SSF50475 21 144 1.63E-17 T 12-10-2018 AFR_12100 0046dfd4e42e90285dfb98e7b5f5d38f 284 Pfam PF14015 Protein of unknown function (DUF4231) 14 102 9.6E-6 T 12-10-2018 IPR025325 Protein of unknown function DUF4231 AFR_37725 935d6551ab219e1c69ba4879a76ce8fe 124 Pfam PF14325 Domain of unknown function (DUF4383) 20 122 1.7E-7 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 AFR_10040 f11bfd70ad5f7523878353430e5b0933 101 Pfam PF02325 YGGT family 11 91 7.8E-11 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 AFR_02970 690898d19ee9db0c0d2c0ce20a911988 250 Pfam PF03448 MgtE intracellular N domain 42 131 3.0E-7 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFR_02970 690898d19ee9db0c0d2c0ce20a911988 250 SUPERFAMILY SSF158791 42 131 1.92E-7 T 12-10-2018 AFR_22560 241909887f21a235fea359167a35e862 235 Pfam PF04973 Nicotinamide mononucleotide transporter 26 216 1.0E-49 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 AFR_25190 4cd00df6ea064605414f7b1511bc4b75 258 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 20 243 4.7E-36 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFR_25190 4cd00df6ea064605414f7b1511bc4b75 258 Gene3D G3DSA:3.20.20.190 15 252 7.2E-66 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_25190 4cd00df6ea064605414f7b1511bc4b75 258 SUPERFAMILY SSF51695 14 248 8.11E-61 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFR_33660 45be7f2e7bb380a14b8ce179e489928d 373 SUPERFAMILY SSF55874 258 370 8.46E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33660 45be7f2e7bb380a14b8ce179e489928d 373 Gene3D G3DSA:3.30.565.10 252 371 5.8E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_33660 45be7f2e7bb380a14b8ce179e489928d 373 Pfam PF07730 Histidine kinase 177 242 2.4E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFR_15325 62e1d73a19ddf0ca38e5b4ef2bd6d07c 228 Pfam PF06197 Protein of unknown function (DUF998) 28 216 5.6E-37 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_16020 f60ba996dfe168e4caac123d2f4a05b8 452 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 4 452 1.4E-119 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AFR_16020 f60ba996dfe168e4caac123d2f4a05b8 452 Pfam PF02397 Bacterial sugar transferase 257 446 1.3E-65 T 12-10-2018 IPR003362 Bacterial sugar transferase AFR_35850 a7069a485e07786dbf68774427e783c4 173 Pfam PF10825 Protein of unknown function (DUF2752) 76 123 5.3E-17 T 12-10-2018 IPR021215 Protein of unknown function DUF2752 AFR_37370 29a21b6f3161e8e960f2d08ce17e4fa6 53 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 1 49 3.7E-7 T 12-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter AFR_26480 092a32c381d515c0ffc71eb333396047 245 Pfam PF04228 Putative neutral zinc metallopeptidase 55 236 6.0E-11 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative AFR_21400 9f2fe04ed70c3ec549dd67b88e6e8e2b 187 Pfam PF06353 Protein of unknown function (DUF1062) 30 163 6.9E-36 T 12-10-2018 IPR009412 Protein of unknown function DUF1062 AFR_27235 f7b428ae39ed4be98c67fbfefa05d29a 286 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 217 9.5E-14 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFR_25095 de775a570dfdcf3c01026a30dd9daa76 602 SUPERFAMILY SSF54909 206 599 2.15E-87 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFR_22840 f70f919ff4d94c939407f50f4670caf2 181 Pfam PF14024 Protein of unknown function (DUF4240) 1 111 6.5E-24 T 12-10-2018 IPR025334 Domain of unknown function (DUF4240 AFR_24625 6c0d2a403bb17fcf1cd94e10e6edf431 293 Pfam PF02517 CAAX protease self-immunity 126 222 1.8E-11 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFR_33350 0de61ebe36141c637555424683393966 92 Pfam PF02325 YGGT family 10 91 8.1E-16 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 AFR_10630 113374530bf333793597ddc81d6d2a61 481 SUPERFAMILY SSF53697 58 321 3.34E-7 T 12-10-2018 AFR_30360 545e8d0660274206cec7d58f2a699694 439 Pfam PF02687 FtsX-like permease family 87 180 9.9E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_08750 887c3acfb5d1652d45efd938d027228c 330 Pfam PF06224 Winged helix DNA-binding domain 29 323 1.4E-36 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 AFR_05425 a36c97ec8716ede8a8e663bd7cd9ee5e 118 Pfam PF06803 Protein of unknown function (DUF1232) 54 89 5.3E-12 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 AFR_08895 c41f7e7ca03719563f922bb566c07609 244 Pfam PF02591 C4-type zinc ribbon domain 202 236 1.1E-10 T 12-10-2018 IPR003743 C4-type zinc ribbon domain AFR_35180 5a81cea19d94aff67fa0441a299a9f80 190 Pfam PF11452 Protein of unknown function (DUF3000) 8 178 6.8E-71 T 12-10-2018 IPR021555 Protein of unknown function DUF3000 AFR_07990 981946d0d3fca033b078a3ed52b7fdfe 267 Pfam PF13349 Putative adhesin 42 261 5.4E-14 T 12-10-2018 IPR025164 Putative adhesin AFR_19645 7ce7aa22fb99d26fdd1adfa2fd73a411 252 SUPERFAMILY SSF51126 12 232 4.11E-15 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor AFR_22925 0fe272a88883566ed51caf59f58c0f04 343 SUPERFAMILY SSF50965 134 327 2.48E-5 T 12-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller AFR_38105 2d0fc1be881575aedfaaa4074fe292c2 542 SUPERFAMILY SSF48452 155 269 9.49E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFR_06785 077709e76bf16c9cf7766a1317eba5a7 307 Pfam PF00482 Type II secretion system (T2SS), protein F 169 294 3.0E-20 T 12-10-2018 IPR018076 Type II secretion system F domain AFR_40640 0e6837be6bdd5f8ef443163579c66546 270 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 26 244 2.6E-31 T 12-10-2018 AFR_12745 4b4af2c4e2fe5d083e377f7b8c77a553 174 SUPERFAMILY SSF53474 2 171 2.7E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_39560 d0c0b487cb14d504ea0ff8a96550b917 225 Pfam PF14094 Domain of unknown function (DUF4272) 14 220 3.6E-48 T 12-10-2018 IPR025368 Protein of unknown function DUF4272 AFR_25635 ebf80bd47a949ae549bb6755a959ca54 530 Pfam PF01757 Acyltransferase family 4 326 2.5E-21 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_36285 25a18a438e58e7df1596bf56b0c83ce1 108 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 2.8E-53 T 12-10-2018 IPR019592 Protein of unknown function DUF2469 AFR_00980 c36ec5e349e992da5f48f65e45006be1 138 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 14 129 1.2E-30 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III AFR_39535 e76cfb589916ead9bd34634b37c8e634 126 Pfam PF05331 Protein of unknown function (DUF742) 10 126 4.6E-28 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_35115 69879c28fd6ad9c75b7e51e99959c979 165 Pfam PF00746 LPXTG cell wall anchor motif 126 163 2.8E-5 T 12-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor AFR_35115 69879c28fd6ad9c75b7e51e99959c979 165 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 130 163 0.0022 T 12-10-2018 AFR_31000 181036bc9715b657c02f1a3d77662c6c 178 Gene3D G3DSA:3.40.50.1820 11 176 1.0E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_31000 181036bc9715b657c02f1a3d77662c6c 178 SUPERFAMILY SSF53474 6 175 4.85E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28865 6d538193f99639d7aaa1dd51c1d793a0 531 SUPERFAMILY SSF53474 112 499 3.34E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFR_28865 6d538193f99639d7aaa1dd51c1d793a0 531 Pfam PF00561 alpha/beta hydrolase fold 116 500 1.7E-45 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFR_00800 52af011099879a563ed98e4d9fc56978 431 Pfam PF13367 Protease prsW family 87 277 5.0E-38 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 AFR_20030 774ddf11ac7426e2ef3835d02511f6a6 353 Pfam PF12224 Putative amidoligase enzyme 7 316 2.8E-24 T 12-10-2018 IPR022025 Putative amidoligase enzyme AFR_11525 a5d187f80dbbb5a76757df5a5d58ab10 359 Pfam PF06224 Winged helix DNA-binding domain 34 353 2.4E-46 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 AFR_03115 8521db005b2d8d05f5725df1dd8ed529 171 Gene3D G3DSA:3.20.90.20 1 159 1.2E-14 T 12-10-2018 IPR038595 LURP-one-related superfamily AFR_03115 8521db005b2d8d05f5725df1dd8ed529 171 Pfam PF04525 LURP-one-related 3 149 1.3E-19 T 12-10-2018 IPR007612 LURP-one-related AFR_03115 8521db005b2d8d05f5725df1dd8ed529 171 SUPERFAMILY SSF54518 2 153 5.23E-35 T 12-10-2018 IPR025659 Tubby-like, C-terminal AFR_41385 d1669833c08444f84f768d8fa5cd1cac 304 Pfam PF13845 Septum formation 52 278 2.9E-49 T 12-10-2018 IPR026004 Septum formation-related domain AFR_33385 53ee9b720dcf2e25d1dbce7f8601e101 737 Pfam PF02687 FtsX-like permease family 642 723 4.9E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_14265 d277f3c6eca5be1fe0b442571898b85c 86 Pfam PF11239 Protein of unknown function (DUF3040) 3 75 9.7E-12 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 AFR_13160 1bf7f88bfb3336aa4fa52221e60047da 465 Pfam PF09852 Predicted membrane protein (DUF2079) 37 453 3.4E-69 T 12-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 AFR_16405 2e2d7e3012efed270815e053676208b8 355 Pfam PF11017 Protein of unknown function (DUF2855) 40 345 3.7E-99 T 12-10-2018 IPR021276 Protein of unknown function DUF2855 AFR_15725 3d7a44d32ea617a8f6383dd99dc93686 303 Gene3D G3DSA:2.60.120.10 183 288 1.1E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFR_15725 3d7a44d32ea617a8f6383dd99dc93686 303 SUPERFAMILY SSF51182 154 292 7.02E-9 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFR_31580 06cd7d3a244d54a3dbbc144e0e17b94b 246 SUPERFAMILY SSF56634 21 228 5.37E-10 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 AFR_14620 965b5a941c996439c6c26e47ad3c37fb 201 Pfam PF14124 Domain of unknown function (DUF4291) 9 187 1.1E-65 T 12-10-2018 IPR025633 Protein of unknown function DUF4291 AFR_30135 cb57e3c104b97f3bca70bd63064e8c08 134 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 106 3.9E-25 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like AFR_34520 fd525ea70388576b1a8622b88e0335ae 174 SUPERFAMILY SSF54518 22 127 6.54E-6 T 12-10-2018 IPR025659 Tubby-like, C-terminal AFR_42455 8d34a39d75c725c6a7f85fc173489eaf 112 Pfam PF04341 Protein of unknown function, DUF485 29 101 2.7E-7 T 12-10-2018 IPR007436 Protein of unknown function DUF485 AFR_00990 c7e60b98e82707d0ac38e1d21a639d62 90 Pfam PF14019 Protein of unknown function (DUF4235) 10 86 1.6E-25 T 12-10-2018 IPR025329 Protein of unknown function DUF4235 AFR_28175 746313b155790ae8b5055bdac175f9b6 722 SUPERFAMILY SSF52540 52 258 5.09E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFR_28380 c70c3e5fb8d81cf188e87be6d5ec7af3 563 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 8 327 9.1E-120 T 12-10-2018 IPR010839 Acyclic terpene utilisation AFR_01090 f901adf3238abb6f7041414b0c23b2c4 167 Pfam PF14106 Domain of unknown function (DUF4279) 40 158 4.9E-24 T 12-10-2018 IPR025459 Protein of unknown function DUF4279 AFR_40005 3a38a0ba22d5dcbdbf01858b8a4b463f 168 Pfam PF13828 Domain of unknown function (DUF4190) 95 147 2.4E-16 T 12-10-2018 IPR025241 Domain of unknown function DUF4190 AFR_19695 3946c748956cb6eb6248651169b12440 372 Pfam PF09594 Glycosyltransferase family 87 60 280 3.9E-53 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 AFR_28840 b1915ed19d5479f91d229901ce842b22 399 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 25 379 3.1E-93 T 12-10-2018 IPR010640 Low temperature requirement A AFR_09075 1f1dd5afbb7bddd97d130510d35cf93c 527 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 189 5.0E-6 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFR_12370 463ee6b4fe22d0c262c8c6af65f9b96e 287 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 11 220 2.1E-15 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFR_08265 ec7fd0b22cb2dc99c90f9415fe881a3f 52 Pfam PF00815 Histidinol dehydrogenase 1 44 2.3E-7 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFR_36160 a0aca49e85a83d4a1a72594db6e3ca40 282 Pfam PF03631 Virulence factor BrkB 1 234 3.2E-16 T 12-10-2018 IPR017039 Virulence factor BrkB AFR_01610 c59cfbad2802a8e8a4f6998358fb66a9 277 Pfam PF04434 SWIM zinc finger 146 166 3.7E-5 T 12-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 AFR_28630 6a5fd31795636f4e281b422e7dc9a656 402 Pfam PF04188 Mannosyltransferase (PIG-V) 74 215 1.6E-9 T 12-10-2018 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 Reactome: R-HSA-162710 AFR_25020 076b50181fd508409ebecd6d04a34ecc 318 Pfam PF07760 Protein of unknown function (DUF1616) 9 193 3.0E-11 T 12-10-2018 IPR011674 Domain of unknown function DUF1616 AFR_32475 9fd9256a381b883fa28aedc3d0cd4af0 124 SUPERFAMILY SSF103196 3 122 3.19E-5 T 12-10-2018 AFR_06185 c8c58645a9703e709e58ba92d88b0bae 242 Gene3D G3DSA:3.40.50.12500 1 242 7.2E-87 T 12-10-2018 AFR_06185 c8c58645a9703e709e58ba92d88b0bae 242 Pfam PF01177 Asp/Glu/Hydantoin racemase 3 204 3.1E-13 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFR_09835 282bea002b777afa7ecc5ba7845f1e8b 255 Pfam PF04240 Carotenoid biosynthesis protein 33 236 1.7E-36 T 12-10-2018 IPR007354 Carotene biosynthesis associated membrane protein AFR_18955 953b84acef982ecbe7dbe4ba39591a92 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 325 7.3E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_34080 3048a112811d6e8af406a5c562f80241 233 SUPERFAMILY SSF55154 16 84 2.88E-5 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 AFR_29970 593aa332963bf0b2d169dfd1ec2a2d66 273 Pfam PF12730 ABC-2 family transporter protein 5 194 9.7E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFR_10890 d2141f03253613c8cb88e1f4a5c60b60 305 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 23 250 4.8E-43 T 12-10-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain AFR_38875 921a8c9c6b02f9ed4074c1119490a942 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 22 303 3.6E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_23375 cad9c7fceca1bc7725d0e92a495330c2 149 Pfam PF01609 Transposase DDE domain 29 124 4.2E-5 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 AFR_26210 ba48c1d5244afb32d34a09cbce1acc8f 767 Pfam PF02687 FtsX-like permease family 272 365 3.3E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_34270 9b8423a8336789a4513f359b4c75aa23 496 Gene3D G3DSA:1.25.10.10 7 102 1.5E-5 T 12-10-2018 IPR011989 Armadillo-like helical AFR_34270 9b8423a8336789a4513f359b4c75aa23 496 Gene3D G3DSA:1.25.10.10 316 482 3.3E-12 T 12-10-2018 IPR011989 Armadillo-like helical AFR_34270 9b8423a8336789a4513f359b4c75aa23 496 Gene3D G3DSA:1.25.10.10 103 295 2.3E-8 T 12-10-2018 IPR011989 Armadillo-like helical AFR_29595 0254342fe671a53957477f19e71ac7a2 662 Pfam PF03235 Protein of unknown function DUF262 12 212 8.5E-26 T 12-10-2018 IPR004919 Domain of unknown function DUF262 AFR_28740 295c8eb001e23c1bf6969cf47c30d955 153 SUPERFAMILY SSF88697 16 143 3.08E-10 T 12-10-2018 IPR015947 PUA-like superfamily AFR_36830 b47f10b1bacdcf3ab8fd694ca4a9f5e7 246 Pfam PF01061 ABC-2 type transporter 20 212 2.4E-13 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFR_17895 fcde0a149828485ef8e4cf4f61991ae4 195 Pfam PF06197 Protein of unknown function (DUF998) 3 189 6.2E-24 T 12-10-2018 IPR009339 Protein of unknown function DUF998 AFR_38085 024c7e8b37025b99fc6902a3f86965dc 490 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 56 197 4.9E-12 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFR_26370 593f1d43cfd6171b0bcfad73645832d5 360 Pfam PF12982 Protein of unknown function (DUF3866) 32 352 1.2E-127 T 12-10-2018 IPR024479 Protein of unknown function DUF3866 AFR_35735 37ac40b41363ca052b2ae24256532452 267 Pfam PF14344 Domain of unknown function (DUF4397) 21 142 6.9E-27 T 12-10-2018 IPR025510 Domain of unknown function DUF4397 AFR_06060 851fcaddf0316c435fe5dcf34142b899 477 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 11 104 4.0E-15 T 12-10-2018 IPR026337 HEXXH motif domain AFR_06060 851fcaddf0316c435fe5dcf34142b899 477 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 112 319 7.9E-68 T 12-10-2018 IPR026337 HEXXH motif domain AFR_36940 4557e6120c67bfa31f4326288bfda0ac 91 Gene3D G3DSA:3.10.20.30 3 91 2.1E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFR_36940 4557e6120c67bfa31f4326288bfda0ac 91 Pfam PF02597 ThiS family 6 91 9.6E-11 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFR_36940 4557e6120c67bfa31f4326288bfda0ac 91 SUPERFAMILY SSF54285 1 91 6.92E-16 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFR_38160 41924be6fb4aa31621f2d7a9f31205e8 257 Gene3D G3DSA:3.30.565.10 114 240 1.6E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFR_38160 41924be6fb4aa31621f2d7a9f31205e8 257 Gene3D G3DSA:3.30.750.24 2 108 4.3E-7 T 12-10-2018 IPR036513 STAS domain superfamily AFR_11260 bd02a2c65d185b24b41d066c2e39e1f1 125 Pfam PF05331 Protein of unknown function (DUF742) 15 123 2.0E-30 T 12-10-2018 IPR007995 Protein of unknown function DUF742 AFR_14475 bedd3153fce64410073195d6ebf76cf7 374 SUPERFAMILY SSF53137 146 224 9.29E-7 T 12-10-2018 AFR_34880 90b8de25ae166f8e01b8fc11442d18e9 231 Pfam PF03640 Secreted repeat of unknown function 141 183 1.3E-14 T 12-10-2018 IPR005297 Lipoprotein repeat AFR_34880 90b8de25ae166f8e01b8fc11442d18e9 231 Pfam PF03640 Secreted repeat of unknown function 82 122 2.0E-12 T 12-10-2018 IPR005297 Lipoprotein repeat AFR_22000 05ba38bd15751351f1e8d6283acf3904 160 Pfam PF10002 Predicted membrane protein (DUF2243) 9 156 9.2E-54 T 12-10-2018 IPR018719 Protein of unknown function DUF2243, membrane AFR_13070 47614be0c2cb1d8353f06601258aac26 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 317 1.4E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFR_22390 a9899ceef294c1ec4811b72a46dbaada 626 Pfam PF02687 FtsX-like permease family 92 187 2.8E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFR_20890 9408bca535bf1117624bd2252e825f18 232 Pfam PF10099 Anti-sigma-K factor rskA 59 228 6.2E-20 T 12-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 AFR_11010 9e41ddba7eaae1b4da720392744658a3 337 Pfam PF01882 Protein of unknown function DUF58 50 133 4.0E-17 T 12-10-2018 IPR002881 Domain of unknown function DUF58 AFR_03085 e02723287adbfee9a3d7603478cb916e 117 Pfam PF13298 DNA polymerase Ligase (LigD) 9 98 1.3E-17 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain AFR_36390 0f6edc9d4060852723fcb373b7aaf58f 695 Pfam PF01757 Acyltransferase family 37 357 1.5E-26 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFR_35340 a155cd896784733ca1b73a28abcb652c 204 Pfam PF03458 UPF0126 domain 9 83 3.3E-19 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 AFR_35340 a155cd896784733ca1b73a28abcb652c 204 Pfam PF03458 UPF0126 domain 95 167 6.2E-20 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 AFR_40845 a8fb542edc1e2ea207c01e0546fef222 401 Pfam PF13515 Fusaric acid resistance protein-like 48 169 7.0E-12 T 12-10-2018 AFR_02035 01fc94ad54020db75ce704a02d29ac7c 117 Pfam PF06993 Protein of unknown function (DUF1304) 10 114 1.6E-38 T 12-10-2018 IPR009732 Protein of unknown function DUF1304 AFR_08420 64470a7cad3dea9a37f1b9c9c87305eb 240 Pfam PF14329 Domain of unknown function (DUF4386) 7 211 2.7E-41 T 12-10-2018 IPR025495 Protein of unknown function DUF4386 AFR_05330 8be4d55359bff937d9ff54d59225a95e 207 Pfam PF04977 Septum formation initiator 92 164 4.8E-17 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC AFR_42945 572123c07b12d8098b9566c3227b2418 221 Gene3D G3DSA:3.40.630.30 11 141 4.3E-7 T 12-10-2018 AFR_42945 572123c07b12d8098b9566c3227b2418 221 SUPERFAMILY SSF55729 1 175 1.84E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFR_06810 c0e61101e0406b589c1b45d4d1e25414 372 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 13 62 1.4E-6 T 12-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal AFR_20990 a606aad9866178c6b2d995a3619b54ed 468 Pfam PF14224 Domain of unknown function (DUF4331) 2 456 7.8E-147 T 12-10-2018 IPR025566 Protein of unknown function DUF4331 AFR_16240 45cdedc1d52b8f226474fbd61538d6b4 671 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 101 412 5.1E-36 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 AFR_41075 0ee7e77c6b0457fd64faee6c863efc21 395 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 26 379 1.9E-94 T 12-10-2018 IPR010640 Low temperature requirement A AFR_38220 f632265ed06531d013fe82d32d3c96bb 59 Pfam PF14013 MT0933-like antitoxin protein 4 51 1.1E-19 T 12-10-2018 IPR028037 Antitoxin Rv0909/MT0933 AFR_32835 ee6da8e8dca6eb4a08796b56c9d42e62 142 Pfam PF14108 Domain of unknown function (DUF4281) 5 129 2.8E-41 T 12-10-2018 IPR025461 ABA DEFICIENT 4-like AFR_05750 564fd2f8134c4d9daa2556238346a29c 290 Pfam PF03239 Iron permease FTR1 family 1 254 7.8E-51 T 12-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 AFR_35040 28c8471e16e78da0e7162ad385114d0b 125 Pfam PF11236 Protein of unknown function (DUF3037) 7 124 1.6E-41 T 12-10-2018 IPR021398 Protein of unknown function DUF3037 AFR_10935 b0475c36153ad87e8f1eefdd3a3eb704 129 SUPERFAMILY SSF54427 4 97 5.59E-5 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFR_07435 d35c99525fe2d408173d6d90f55f262a 200 SUPERFAMILY SSF101967 23 167 6.28E-6 T 12-10-2018 AFR_31375 18b69f632c704189db056a27678b1121 447 Pfam PF05552 Conserved TM helix 10 56 2.8E-13 T 12-10-2018 IPR008910 Conserved TM helix AFR_09315 db2c4ab99088cbbc7aa9249aa16cae6e 266 Pfam PF06182 ABC-2 family transporter protein 36 265 2.1E-44 T 12-10-2018 IPR010390 Protein of unknown function DUF990 AFR_02810 9fa02505e790c943f31d5bf511443973 527 SUPERFAMILY SSF53756 174 427 1.55E-7 T 12-10-2018 AFR_19780 5e6ba0ca322e3de25d60956e586e01cb 119 Gene3D G3DSA:3.10.180.10 2 119 9.2E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_19780 5e6ba0ca322e3de25d60956e586e01cb 119 SUPERFAMILY SSF54593 5 117 3.47E-14 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFR_40920 2e086f29af916ab4de6bb0074beb3ccf 103 Pfam PF11662 Protein of unknown function (DUF3263) 30 101 4.4E-35 T 12-10-2018 IPR021678 Protein of unknown function DUF3263 AFR_22205 dc0206bd6cd4b6088fb027d3180b395c 194 Pfam PF07681 DoxX 44 144 1.2E-5 T 12-10-2018 IPR032808 DoxX family AFR_10095 e1a49907c31b928a01148e51a87d44b6 244 Pfam PF10821 Protein of unknown function (DUF2567) 53 149 3.5E-8 T 12-10-2018 IPR021213 Protein of unknown function DUF2567 AFR_35420 9868f935c630b7455588366cf145ba5e 117 Pfam PF10823 Protein of unknown function (DUF2568) 7 98 6.4E-26 T 12-10-2018 IPR021214 Protein of unknown function DUF2568 AFR_39405 81d264687a013bc5b29c4d46a5543ebb 313 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 298 6.3E-85 T 12-10-2018 IPR007296 Domain of unknown function DUF403