locus-tag	class	description
AMIS_10010	COG4209	transmembrane transport
AMIS_10020	COG0395	ABC-type sugar transport system, permease component
AMIS_10070	COG0277	FAD linked oxidase domain protein
AMIS_10140	COG0598	Magnesium transport protein CorA
AMIS_10180	COG0456	acetyltransferase
AMIS_10210	COG2124	cytochrome p450
AMIS_10300	COG1609	Transcriptional regulator
AMIS_10320	COG2706	6-phosphogluconolactonase activity
AMIS_10340	COG1940	carbohydrate kinase activity
AMIS_10350	COG2115	Belongs to the xylose isomerase family
AMIS_10360	COG1070	Carbohydrate kinase
AMIS_10400	COG0438	transferase activity, transferring glycosyl groups
AMIS_10420	COG0366	Alpha amylase catalytic
AMIS_10430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMIS_10490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMIS_10620	COG2264	protein methyltransferase activity
AMIS_10670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMIS_10710	COG0629	single-stranded DNA binding
AMIS_10730	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMIS_10740	COG0640	Transcriptional regulator
AMIS_10750	COG1492	cobalamin metabolic process
AMIS_10760	COG0501	Belongs to the peptidase M48B family
AMIS_10770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_10800	COG1793	dna ligase
AMIS_10830	COG1797	cobyrinic acid a,c-diamide synthase activity
AMIS_10870	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AMIS_10880	COG1648	precorrin-2 dehydrogenase activity
AMIS_10880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMIS_10890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AMIS_10980	COG0668	transmembrane transport
AMIS_11030	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AMIS_11060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMIS_1110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMIS_11100	COG0698	ribose 5-phosphate isomerase
AMIS_11130	COG4552	Acetyltransferase involved in intracellular survival and related
AMIS_11150	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_11190	COG0640	Transcriptional regulator
AMIS_1120	COG0151	Belongs to the GarS family
AMIS_11220	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMIS_11230	COG0740	serine-type endopeptidase activity
AMIS_11240	COG0740	serine-type endopeptidase activity
AMIS_11250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMIS_11260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMIS_11290	COG0525	valine-tRNA ligase activity
AMIS_11300	COG0285	dihydrofolate synthase activity
AMIS_11330	COG0105	UTP biosynthetic process
AMIS_11340	COG5002	protein histidine kinase activity
AMIS_11350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMIS_11380	COG0596	Alpha beta hydrolase
AMIS_11430	COG1530	ribonuclease E activity
AMIS_11440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMIS_11450	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMIS_11460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMIS_11470	COG2153	protein acetylation
AMIS_11480	COG0180	Tryptophanyl-tRNA synthetase
AMIS_1150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMIS_11510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMIS_11530	COG0406	alpha-ribazole phosphatase activity
AMIS_11550	COG1307	EDD domain protein, DegV family
AMIS_11570	COG2890	protein-(glutamine-N5) methyltransferase activity
AMIS_11590	COG0658	competence protein
AMIS_11590	COG2333	competence protein COMEC
AMIS_11630	COG0268	Binds directly to 16S ribosomal RNA
AMIS_11670	COG0481	GTPase activity
AMIS_11680	COG2261	transglycosylase associated protein
AMIS_1170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMIS_11710	COG1024	Enoyl-CoA hydratase
AMIS_11740	COG1420	regulation of RNA biosynthetic process
AMIS_11750	COG0484	heat shock protein binding
AMIS_11790	COG0537	adenosine 5'-monophosphoramidase activity
AMIS_1180	COG0047	phosphoribosylformylglycinamidine synthase activity
AMIS_11820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMIS_11850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMIS_11880	COG1381	Involved in DNA repair and RecF pathway recombination
AMIS_11890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMIS_1190	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMIS_11970	COG4172	Belongs to the ABC transporter superfamily
AMIS_11980	COG4721	ABC-type cobalt transport system, permease component
AMIS_11990	COG0596	Alpha beta hydrolase
AMIS_12040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMIS_12050	COG1121	(ABC) transporter
AMIS_12100	COG0423	glycine-tRNA ligase activity
AMIS_12110	COG3608	succinylglutamate desuccinylase aspartoacylase
AMIS_12110	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AMIS_12150	COG2197	response regulator
AMIS_12190	COG2018	Roadblock/LC7 domain
AMIS_12230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMIS_12290	COG1295	ribonuclease BN
AMIS_1230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMIS_12300	COG1846	Transcriptional regulator
AMIS_12300	COG1940	carbohydrate kinase activity
AMIS_12310	COG1129	ABC transporter
AMIS_12320	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIS_1240	COG0641	radical SAM
AMIS_12430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMIS_12510	COG1505	serine-type exopeptidase activity
AMIS_12610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMIS_12620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMIS_12630	COG1414	Transcriptional regulator
AMIS_12640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMIS_12660	COG3693	PFAM glycoside hydrolase, family 10
AMIS_12660	COG2382	esterase
AMIS_12680	COG3979	chitinase
AMIS_12720	COG1196	nuclear chromosome segregation
AMIS_12720	COG0741	lytic transglycosylase activity
AMIS_12720	COG0739	heme binding
AMIS_12880	COG0477	Major facilitator Superfamily
AMIS_12890	COG0018	arginyl-trna synthetase
AMIS_12900	COG0737	Belongs to the 5'-nucleotidase family
AMIS_12920	COG0515	serine threonine protein kinase
AMIS_12950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMIS_12960	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMIS_12960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMIS_13000	COG3973	AAA domain
AMIS_13050	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIS_13080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIS_13090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMIS_1310	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AMIS_13150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMIS_13160	COG0840	transmembrane signaling receptor activity
AMIS_13170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMIS_13180	COG0432	Pfam Uncharacterised protein family UPF0047
AMIS_13190	COG0022	dehydrogenase e1 component
AMIS_13270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMIS_13290	COG0406	alpha-ribazole phosphatase activity
AMIS_13290	COG0328	RNA-DNA hybrid ribonuclease activity
AMIS_13360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIS_13380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMIS_13400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMIS_13420	COG0730	response to heat
AMIS_13430	COG2226	methyltransferase
AMIS_13470	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AMIS_13480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMIS_13490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMIS_13490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMIS_13500	COG0174	glutamine synthetase
AMIS_13520	COG1595	DNA-templated transcription, initiation
AMIS_13530	COG3766	membrane
AMIS_13540	COG1064	alcohol dehydrogenase
AMIS_13560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMIS_13580	COG1846	Transcriptional regulator
AMIS_13620	COG5650	phosphatidylinositol metabolic process
AMIS_13710	COG1404	Belongs to the peptidase S8 family
AMIS_13740	COG1674	ftsk spoiiie
AMIS_13800	COG1672	PFAM Archaeal ATPase
AMIS_13800	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMIS_13820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMIS_13830	COG0017	Asparaginyl-tRNA synthetase
AMIS_13850	COG0321	lipoyl(octanoyl) transferase activity
AMIS_13880	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIS_13890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMIS_13910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMIS_13920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMIS_13930	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AMIS_13960	COG1994	Peptidase M50
AMIS_13970	COG0667	Aldo Keto reductase
AMIS_14020	COG4555	ABC transporter
AMIS_14040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AMIS_14070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMIS_14080	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMIS_14090	COG1929	Belongs to the glycerate kinase type-1 family
AMIS_14130	COG0425	Belongs to the sulfur carrier protein TusA family
AMIS_14150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMIS_14180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMIS_14220	COG2010	Cytochrome c
AMIS_14240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMIS_14260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMIS_14280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMIS_14320	COG0501	Belongs to the peptidase M48B family
AMIS_14330	COG0438	transferase activity, transferring glycosyl groups
AMIS_14380	COG2197	response regulator
AMIS_14420	COG1940	carbohydrate kinase activity
AMIS_14440	COG2072	flavoprotein involved in K transport
AMIS_1450	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AMIS_14550	COG2211	Major facilitator Superfamily
AMIS_14560	COG1940	carbohydrate kinase activity
AMIS_14560	COG1846	Transcriptional regulator
AMIS_14590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMIS_14690	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMIS_14710	COG0504	CTP synthase activity
AMIS_14730	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AMIS_14740	COG0515	serine threonine protein kinase
AMIS_14740	COG2815	serine threonine protein kinase
AMIS_14820	COG1309	transcriptional regulator
AMIS_14840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMIS_14850	COG1053	succinate dehydrogenase
AMIS_14880	COG2226	methyltransferase
AMIS_14900	COG1233	COG1233 Phytoene dehydrogenase and related
AMIS_1500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMIS_15020	COG0587	DNA-directed DNA polymerase activity
AMIS_15040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMIS_15090	COG0714	Associated with various cellular activities
AMIS_15100	COG0495	leucyl-tRNA aminoacylation
AMIS_15120	COG3442	glutamine amidotransferase
AMIS_15130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMIS_15150	COG2001	Belongs to the MraZ family
AMIS_15160	COG0275	rRNA processing
AMIS_15180	COG0768	penicillin binding
AMIS_15190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMIS_15210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMIS_15230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMIS_15240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMIS_15250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMIS_15260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMIS_15270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMIS_15280	COG1799	cell septum assembly
AMIS_15300	COG3599	regulation of cell shape
AMIS_15340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMIS_15380	COG0587	DNA-directed DNA polymerase activity
AMIS_15400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMIS_15410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMIS_15420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMIS_15430	COG0131	Imidazoleglycerol-phosphate dehydratase
AMIS_15450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMIS_15470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMIS_15480	COG0583	DNA-binding transcription factor activity
AMIS_15500	COG0107	imidazoleglycerol-phosphate synthase activity
AMIS_15530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_15540	COG1022	Amp-dependent synthetase and ligase
AMIS_15560	COG1132	(ABC) transporter
AMIS_15570	COG1132	(ABC) transporter
AMIS_15580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMIS_1560	COG0438	transferase activity, transferring glycosyl groups
AMIS_15610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMIS_15660	COG0133	tryptophan synthase activity
AMIS_15670	COG0159	tryptophan synthase activity
AMIS_15680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMIS_15690	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AMIS_15690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIS_15710	COG0069	glutamate synthase activity
AMIS_15710	COG0067	glutamate synthase
AMIS_15710	COG0070	glutamate synthase
AMIS_15770	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMIS_15800	COG0410	ABC transporter
AMIS_15870	COG0539	negative regulation of cytoplasmic translation
AMIS_15880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMIS_15880	COG0237	dephospho-CoA kinase activity
AMIS_1590	COG0438	transferase activity, transferring glycosyl groups
AMIS_15900	COG2329	Antibiotic biosynthesis monooxygenase
AMIS_15910	COG0861	Integral membrane protein TerC family
AMIS_15940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMIS_15950	COG0740	serine-type endopeptidase activity
AMIS_160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMIS_16020	COG1162	GTPase activity
AMIS_16060	COG0322	excinuclease ABC activity
AMIS_16070	COG1660	Displays ATPase and GTPase activities
AMIS_16090	COG1481	regulation of sporulation
AMIS_16100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMIS_16110	COG0126	phosphoglycerate kinase activity
AMIS_16120	COG0149	triose-phosphate isomerase activity
AMIS_16130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMIS_16150	COG0456	acetyltransferase
AMIS_16160	COG0363	glucosamine-6-phosphate deaminase activity
AMIS_16190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMIS_16210	COG0109	protoheme IX farnesyltransferase activity
AMIS_16290	COG0396	ATPase activity
AMIS_16300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMIS_16310	COG0822	iron-sulfur transferase activity
AMIS_16340	COG2267	carboxylic ester hydrolase activity
AMIS_16400	COG2321	neutral zinc metallopeptidase
AMIS_16410	COG0488	(ABC) transporter
AMIS_16430	COG1024	Enoyl-CoA hydratase
AMIS_16440	COG1132	(ABC) transporter
AMIS_16460	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_16470	COG1309	transcriptional regulator
AMIS_1650	COG1970	mechanosensitive ion channel activity
AMIS_16520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMIS_16570	COG3629	intracellular signal transduction
AMIS_16570	COG3903	Transcriptional regulator
AMIS_16580	COG0006	proline dipeptidase activity
AMIS_16640	COG0714	Associated with various cellular activities
AMIS_16670	COG2197	response regulator
AMIS_16680	COG4585	Histidine kinase
AMIS_1670	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_16700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMIS_1680	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_16850	COG0745	RESPONSE REGULATOR receiver
AMIS_1690	COG2172	sigma factor antagonist activity
AMIS_16900	COG1365	unkown
AMIS_16910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMIS_16940	COG1175	transmembrane transport
AMIS_17000	COG0646	methionine synthase
AMIS_17000	COG1410	methionine synthase
AMIS_17030	COG4585	Histidine kinase
AMIS_17040	COG2197	response regulator
AMIS_17060	COG0745	RESPONSE REGULATOR receiver
AMIS_17060	COG3706	GGDEF domain
AMIS_1710	COG2205	protein histidine kinase activity
AMIS_1710	COG0784	Response regulator, receiver
AMIS_17150	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIS_1720	COG0745	RESPONSE REGULATOR receiver
AMIS_17210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMIS_17220	COG3961	Belongs to the TPP enzyme family
AMIS_17230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMIS_17250	COG1309	transcriptional regulator
AMIS_17280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMIS_17310	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_17320	COG0463	Glycosyl transferase, family 2
AMIS_17330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMIS_17350	COG2815	serine threonine protein kinase
AMIS_17350	COG0515	serine threonine protein kinase
AMIS_17390	COG2199	diguanylate cyclase activity
AMIS_17390	COG2200	EAL domain
AMIS_17390	COG2203	Gaf domain
AMIS_1740	COG1136	(ABC) transporter
AMIS_17410	COG1309	transcriptional regulator
AMIS_17420	COG1053	succinate dehydrogenase
AMIS_17430	COG1253	flavin adenine dinucleotide binding
AMIS_17440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AMIS_17450	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMIS_17460	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AMIS_17470	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AMIS_17560	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_17620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMIS_17620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMIS_17630	COG5002	protein histidine kinase activity
AMIS_17640	COG1252	NADH dehydrogenase
AMIS_17660	COG2205	protein histidine kinase activity
AMIS_17670	COG2203	Gaf domain
AMIS_17670	COG2199	diguanylate cyclase activity
AMIS_17670	COG2200	EAL domain
AMIS_17690	COG5002	protein histidine kinase activity
AMIS_17700	COG4251	negative regulation of phosphorylation
AMIS_17710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMIS_1780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AMIS_17810	COG0628	permease
AMIS_17880	COG2197	response regulator
AMIS_1790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AMIS_17940	COG2235	arginine
AMIS_17980	COG0477	Major facilitator Superfamily
AMIS_18030	COG2326	polyphosphate kinase activity
AMIS_18110	COG0531	amino acid
AMIS_18140	COG0477	Major facilitator Superfamily
AMIS_18170	COG2197	response regulator
AMIS_18180	COG1132	(ABC) transporter
AMIS_1820	COG0745	RESPONSE REGULATOR receiver
AMIS_18210	COG1073	alpha beta
AMIS_18300	COG0438	transferase activity, transferring glycosyl groups
AMIS_18310	COG1216	Glycosyl transferase, family 2
AMIS_18390	COG0387	Pfam Sodium calcium exchanger
AMIS_18400	COG0701	Predicted permease
AMIS_18430	COG0019	diaminopimelate decarboxylase activity
AMIS_18440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMIS_18450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMIS_18460	COG4106	trans-aconitate 2-methyltransferase activity
AMIS_1850	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_18520	COG0730	response to heat
AMIS_1860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMIS_18600	COG2720	vancomycin resistance protein
AMIS_18620	COG0784	Response regulator, receiver
AMIS_18620	COG2205	protein histidine kinase activity
AMIS_18620	COG5002	protein histidine kinase activity
AMIS_1870	COG0406	alpha-ribazole phosphatase activity
AMIS_18720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIS_18730	COG0515	serine threonine protein kinase
AMIS_18730	COG2815	serine threonine protein kinase
AMIS_18760	COG1388	LysM domain
AMIS_1880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMIS_18800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AMIS_18860	COG4981	capsule polysaccharide biosynthetic process
AMIS_18880	COG0243	molybdopterin cofactor binding
AMIS_18940	COG4677	pectinesterase activity
AMIS_18950	COG4978	Transcriptional regulator
AMIS_18950	COG0789	Transcriptional regulator
AMIS_190	COG0442	prolyl-tRNA aminoacylation
AMIS_1900	COG1333	cytochrome c biogenesis protein
AMIS_19000	COG1053	succinate dehydrogenase
AMIS_19020	COG1309	transcriptional regulator
AMIS_19030	COG1960	acyl-CoA dehydrogenase activity
AMIS_19040	COG1960	acyl-CoA dehydrogenase activity
AMIS_19080	COG2910	NAD(P)H-binding
AMIS_19100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIS_19110	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AMIS_19140	COG1053	succinate dehydrogenase
AMIS_19150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIS_19180	COG1960	acyl-CoA dehydrogenase activity
AMIS_19190	COG2267	carboxylic ester hydrolase activity
AMIS_19200	COG0346	lactoylglutathione lyase activity
AMIS_19210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMIS_19230	COG1960	acyl-CoA dehydrogenase activity
AMIS_19240	COG1960	acyl-CoA dehydrogenase activity
AMIS_19250	COG1960	acyl-CoA dehydrogenase activity
AMIS_19260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AMIS_19270	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_19280	COG1960	acyl-CoA dehydrogenase activity
AMIS_1930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AMIS_19320	COG0183	Belongs to the thiolase family
AMIS_19330	COG2124	cytochrome p450
AMIS_19350	COG0251	oxidation-reduction process
AMIS_19360	COG3903	Transcriptional regulator
AMIS_19360	COG3629	intracellular signal transduction
AMIS_19460	COG2070	2-Nitropropane dioxygenase
AMIS_19480	COG2188	Transcriptional regulator
AMIS_1950	COG1595	DNA-templated transcription, initiation
AMIS_19680	COG0322	excinuclease ABC activity
AMIS_1970	COG0163	prenyltransferase activity
AMIS_20	COG0592	DNA-directed DNA polymerase activity
AMIS_2010	COG0513	Belongs to the DEAD box helicase family
AMIS_2040	COG0791	NLP P60 protein
AMIS_2040	COG3883	PFAM NLP P60 protein
AMIS_2050	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMIS_2080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMIS_20830	COG4733	cellulase activity
AMIS_20830	COG5297	Belongs to the glycosyl hydrolase family 6
AMIS_2090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_2100	COG1120	ATPase activity
AMIS_21070	COG0305	Participates in initiation and elongation during chromosome replication
AMIS_2110	COG1987	bacterial-type flagellum assembly
AMIS_21140	COG2197	response regulator
AMIS_2140	COG3973	AAA domain
AMIS_21580	COG1132	(ABC) transporter
AMIS_21610	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_21640	COG1960	acyl-CoA dehydrogenase activity
AMIS_21650	COG1960	acyl-CoA dehydrogenase activity
AMIS_21660	COG0183	Belongs to the thiolase family
AMIS_2170	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AMIS_21700	COG1024	Enoyl-CoA hydratase
AMIS_21720	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_21730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIS_21740	COG1309	transcriptional regulator
AMIS_21780	COG1309	transcriptional regulator
AMIS_2180	COG0667	Aldo Keto reductase
AMIS_21800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_2190	COG4279	zinc finger
AMIS_21900	COG3459	Glycosyltransferase 36 associated
AMIS_220	COG0326	Molecular chaperone. Has ATPase activity
AMIS_2200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMIS_22020	COG0277	FAD linked oxidase domain protein
AMIS_22030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIS_22060	COG2197	response regulator
AMIS_22080	COG1132	(ABC) transporter
AMIS_22090	COG1132	(ABC) transporter
AMIS_2210	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMIS_22150	COG1309	transcriptional regulator
AMIS_22170	COG1595	DNA-templated transcription, initiation
AMIS_22200	COG3387	PFAM Glycoside hydrolase 15-related
AMIS_22260	COG0477	Major facilitator Superfamily
AMIS_2230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_22370	COG3629	intracellular signal transduction
AMIS_22370	COG3903	Transcriptional regulator
AMIS_22390	COG0697	spore germination
AMIS_22410	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AMIS_22440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMIS_22480	COG0745	RESPONSE REGULATOR receiver
AMIS_22480	COG3706	GGDEF domain
AMIS_22530	COG3304	Inner membrane component domain
AMIS_22570	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AMIS_22590	COG3033	Beta-eliminating lyase
AMIS_22690	COG2814	Major facilitator Superfamily
AMIS_22760	COG2814	Major facilitator Superfamily
AMIS_22800	COG2188	Transcriptional regulator
AMIS_22840	COG2235	arginine
AMIS_22880	COG4948	Mandelate Racemase Muconate Lactonizing
AMIS_22910	COG3842	ATPase activity
AMIS_22930	COG1609	Transcriptional regulator
AMIS_22980	COG1960	acyl-CoA dehydrogenase activity
AMIS_23000	COG1802	Transcriptional regulator
AMIS_23060	COG0243	molybdopterin cofactor binding
AMIS_23090	COG1136	(ABC) transporter
AMIS_23090	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMIS_23100	COG1136	(ABC) transporter
AMIS_23140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMIS_23150	COG0488	(ABC) transporter
AMIS_23200	COG2357	RelA SpoT domain protein
AMIS_23220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_23240	COG2807	transmembrane transport
AMIS_23380	COG2197	response regulator
AMIS_23390	COG4585	Histidine kinase
AMIS_23490	COG1175	transmembrane transport
AMIS_23510	COG4821	SIS domain
AMIS_23520	COG1737	Transcriptional regulator
AMIS_23560	COG3903	Transcriptional regulator
AMIS_23560	COG3629	intracellular signal transduction
AMIS_23620	COG0583	DNA-binding transcription factor activity
AMIS_23740	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_23770	COG1278	Cold shock
AMIS_23780	COG2197	response regulator
AMIS_23790	COG4585	Histidine kinase
AMIS_23840	COG2409	Drug exporters of the RND superfamily
AMIS_23870	COG3866	Pectate lyase
AMIS_23890	COG0439	Biotin carboxylase
AMIS_23910	COG1253	flavin adenine dinucleotide binding
AMIS_23930	COG1404	Belongs to the peptidase S8 family
AMIS_23940	COG3876	Protein conserved in bacteria
AMIS_23990	COG0583	DNA-binding transcription factor activity
AMIS_24010	COG2409	Drug exporters of the RND superfamily
AMIS_24020	COG4585	Histidine kinase
AMIS_24030	COG2197	response regulator
AMIS_24060	COG2378	regulation of single-species biofilm formation
AMIS_24130	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_24140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIS_24150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMIS_24220	COG2197	response regulator
AMIS_24240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMIS_24260	COG3237	CsbD-like
AMIS_24320	COG0667	Aldo Keto reductase
AMIS_24450	COG1309	transcriptional regulator
AMIS_24460	COG2814	Major facilitator Superfamily
AMIS_24490	COG1122	ATPase activity
AMIS_24510	COG4721	ABC-type cobalt transport system, permease component
AMIS_24530	COG0542	response to heat
AMIS_24550	COG3903	Transcriptional regulator
AMIS_24550	COG3629	intracellular signal transduction
AMIS_24560	COG2186	Transcriptional regulator
AMIS_24590	COG0444	Belongs to the ABC transporter superfamily
AMIS_24600	COG4608	Belongs to the ABC transporter superfamily
AMIS_24620	COG1940	carbohydrate kinase activity
AMIS_24650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIS_24670	COG0596	Alpha beta hydrolase
AMIS_24770	COG1414	Transcriptional regulator
AMIS_24940	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AMIS_24950	COG0028	Belongs to the TPP enzyme family
AMIS_24990	COG3360	Dodecin
AMIS_250	COG0439	Biotin carboxylase
AMIS_25000	COG1396	sequence-specific DNA binding
AMIS_25050	COG2226	methyltransferase
AMIS_25060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMIS_25080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_25140	COG3291	Pkd domain containing protein
AMIS_25180	COG0640	Transcriptional regulator
AMIS_25240	COG3866	Pectate lyase
AMIS_25250	COG0483	inositol monophosphate 1-phosphatase activity
AMIS_25260	COG1846	Transcriptional regulator
AMIS_25310	COG1309	transcriptional regulator
AMIS_25400	COG1673	EVE domain
AMIS_25420	COG0456	acetyltransferase
AMIS_25420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMIS_25430	COG2198	Histidine kinase
AMIS_25430	COG5002	protein histidine kinase activity
AMIS_25430	COG0784	Response regulator, receiver
AMIS_25470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIS_25500	COG0477	Major facilitator Superfamily
AMIS_25540	COG1032	radical SAM domain protein
AMIS_25560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMIS_25570	COG1024	Enoyl-CoA hydratase
AMIS_25700	COG4585	Histidine kinase
AMIS_25720	COG2197	response regulator
AMIS_25770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMIS_25800	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_25910	COG2197	response regulator
AMIS_25920	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_25930	COG0596	Alpha beta hydrolase
AMIS_25970	COG0702	epimerase
AMIS_25980	COG1733	regulation of RNA biosynthetic process
AMIS_260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIS_26060	COG1595	DNA-templated transcription, initiation
AMIS_26080	COG5002	protein histidine kinase activity
AMIS_26090	COG0745	RESPONSE REGULATOR receiver
AMIS_26100	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_26120	COG0577	efflux transmembrane transporter activity
AMIS_26120	COG1136	(ABC) transporter
AMIS_26130	COG0577	efflux transmembrane transporter activity
AMIS_26130	COG1136	(ABC) transporter
AMIS_26150	COG0745	RESPONSE REGULATOR receiver
AMIS_26160	COG5002	protein histidine kinase activity
AMIS_26170	COG0577	efflux transmembrane transporter activity
AMIS_26170	COG1136	(ABC) transporter
AMIS_26180	COG0577	efflux transmembrane transporter activity
AMIS_26180	COG1136	(ABC) transporter
AMIS_26200	COG2197	response regulator
AMIS_26210	COG3850	Histidine kinase
AMIS_26260	COG1733	regulation of RNA biosynthetic process
AMIS_26300	COG1609	Transcriptional regulator
AMIS_26370	COG2272	Belongs to the type-B carboxylesterase lipase family
AMIS_26430	COG0583	DNA-binding transcription factor activity
AMIS_26460	COG5001	Diguanylate cyclase
AMIS_26460	COG4251	negative regulation of phosphorylation
AMIS_26460	COG3706	GGDEF domain
AMIS_26460	COG2203	Gaf domain
AMIS_26520	COG2197	response regulator
AMIS_26530	COG2205	protein histidine kinase activity
AMIS_26580	COG0604	alcohol dehydrogenase
AMIS_26710	COG0431	NADPH-dependent FMN reductase
AMIS_26820	COG1132	(ABC) transporter
AMIS_26840	COG0438	transferase activity, transferring glycosyl groups
AMIS_26850	COG4585	Histidine kinase
AMIS_26860	COG2197	response regulator
AMIS_26870	COG1136	(ABC) transporter
AMIS_26900	COG0586	Pfam SNARE associated Golgi protein
AMIS_26910	COG3263	regulation of cellular component size
AMIS_26930	COG0745	RESPONSE REGULATOR receiver
AMIS_27000	COG1309	transcriptional regulator
AMIS_27030	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_27100	COG1309	transcriptional regulator
AMIS_27120	COG1960	acyl-CoA dehydrogenase activity
AMIS_27130	COG0045	succinate-CoA ligase (ADP-forming) activity
AMIS_27150	COG3706	GGDEF domain
AMIS_27230	COG0535	radical SAM domain protein
AMIS_27270	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_27280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMIS_27300	COG2072	flavoprotein involved in K transport
AMIS_27360	COG0477	Major facilitator Superfamily
AMIS_27380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMIS_27390	COG2409	Drug exporters of the RND superfamily
AMIS_27430	COG2197	response regulator
AMIS_27440	COG4585	Histidine kinase
AMIS_27450	COG1131	(ABC) transporter
AMIS_27470	COG0640	Transcriptional regulator
AMIS_27600	COG3386	PFAM SMP-30 Gluconolaconase
AMIS_27630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIS_27710	COG0583	DNA-binding transcription factor activity
AMIS_27810	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AMIS_27880	COG1414	Transcriptional regulator
AMIS_27900	COG0395	ABC-type sugar transport system, permease component
AMIS_27920	COG0129	dihydroxy-acid dehydratase activity
AMIS_27960	COG3345	alpha-galactosidase
AMIS_27990	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIS_2800	COG2226	methyltransferase
AMIS_28010	COG1733	regulation of RNA biosynthetic process
AMIS_28030	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMIS_28060	COG1121	(ABC) transporter
AMIS_28100	COG0395	ABC-type sugar transport system, permease component
AMIS_28110	COG1175	transmembrane transport
AMIS_28160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMIS_28170	COG1121	(ABC) transporter
AMIS_28190	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMIS_28230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMIS_28240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMIS_28250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMIS_28310	COG3345	alpha-galactosidase
AMIS_28320	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIS_28340	COG3693	PFAM glycoside hydrolase, family 10
AMIS_2840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIS_28430	COG0702	epimerase
AMIS_28490	COG1595	DNA-templated transcription, initiation
AMIS_2850	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIS_28530	COG5001	Diguanylate cyclase
AMIS_28540	COG0667	Aldo Keto reductase
AMIS_28580	COG2366	antibiotic biosynthetic process
AMIS_2860	COG0649	NAD binding
AMIS_28650	COG1595	DNA-templated transcription, initiation
AMIS_28670	COG1309	transcriptional regulator
AMIS_28710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIS_28780	COG2197	response regulator
AMIS_28790	COG5297	Belongs to the glycosyl hydrolase family 6
AMIS_28820	COG3384	dioxygenase
AMIS_28830	COG0784	Response regulator, receiver
AMIS_2890	COG1034	ATP synthesis coupled electron transport
AMIS_28910	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AMIS_28940	COG3415	Transposase
AMIS_28940	COG2801	Transposase and inactivated derivatives
AMIS_290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMIS_2900	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMIS_29060	COG1595	DNA-templated transcription, initiation
AMIS_2910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIS_29110	COG2197	response regulator
AMIS_29190	COG2837	iron assimilation
AMIS_29230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_29240	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_29250	COG1120	ATPase activity
AMIS_29260	COG0473	3-isopropylmalate dehydrogenase activity
AMIS_2930	COG0713	ATP synthesis coupled electron transport
AMIS_29360	COG4585	Histidine kinase
AMIS_29370	COG2197	response regulator
AMIS_29420	COG0778	Nitroreductase
AMIS_29450	COG2211	Major facilitator Superfamily
AMIS_29490	COG1609	Transcriptional regulator
AMIS_29510	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AMIS_29520	COG0840	transmembrane signaling receptor activity
AMIS_2960	COG1007	ATP synthesis coupled electron transport
AMIS_29600	COG2186	Transcriptional regulator
AMIS_29640	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMIS_29650	COG4948	Mandelate Racemase Muconate Lactonizing
AMIS_29710	COG1051	belongs to the nudix hydrolase family
AMIS_29730	COG1846	Transcriptional regulator
AMIS_29730	COG1940	carbohydrate kinase activity
AMIS_29740	COG4209	transmembrane transport
AMIS_29750	COG0395	ABC-type sugar transport system, permease component
AMIS_29790	COG1595	DNA-templated transcription, initiation
AMIS_29890	COG3458	cephalosporin-C deacetylase activity
AMIS_29900	COG3345	alpha-galactosidase
AMIS_29910	COG1940	carbohydrate kinase activity
AMIS_29910	COG1846	Transcriptional regulator
AMIS_29970	COG0745	RESPONSE REGULATOR receiver
AMIS_29980	COG2205	protein histidine kinase activity
AMIS_29990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMIS_30	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AMIS_300	COG1960	acyl-CoA dehydrogenase activity
AMIS_30010	COG0784	Response regulator, receiver
AMIS_30030	COG5002	protein histidine kinase activity
AMIS_30100	COG0659	secondary active sulfate transmembrane transporter activity
AMIS_30110	COG0789	Transcriptional regulator
AMIS_30120	COG1802	Transcriptional regulator
AMIS_30130	COG0477	Major facilitator Superfamily
AMIS_30150	COG0783	Belongs to the Dps family
AMIS_3020	COG1950	PFAM Membrane protein of
AMIS_30310	COG1051	belongs to the nudix hydrolase family
AMIS_30320	COG2205	protein histidine kinase activity
AMIS_30330	COG0745	RESPONSE REGULATOR receiver
AMIS_30350	COG0745	RESPONSE REGULATOR receiver
AMIS_30420	COG4585	Histidine kinase
AMIS_30430	COG2197	response regulator
AMIS_30440	COG2409	Drug exporters of the RND superfamily
AMIS_30460	COG3480	Lon protease (S16) C-terminal proteolytic domain
AMIS_30470	COG5001	Diguanylate cyclase
AMIS_30470	COG3300	MHYT domain
AMIS_30490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMIS_30520	COG0789	Transcriptional regulator
AMIS_30550	COG0254	rRNA binding
AMIS_30580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMIS_30650	COG3509	depolymerase
AMIS_30680	COG1533	DNA photolyase activity
AMIS_30700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AMIS_30730	COG2197	response regulator
AMIS_30770	COG0726	polysaccharide deacetylase
AMIS_30780	COG1053	succinate dehydrogenase
AMIS_3080	COG0596	Alpha beta hydrolase
AMIS_30890	COG0515	serine threonine protein kinase
AMIS_30930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMIS_30960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_30980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMIS_310	COG1846	Transcriptional regulator
AMIS_31000	COG2205	protein histidine kinase activity
AMIS_31020	COG0659	secondary active sulfate transmembrane transporter activity
AMIS_31040	COG0071	Belongs to the small heat shock protein (HSP20) family
AMIS_31050	COG1252	NADH dehydrogenase
AMIS_3110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMIS_31150	COG2203	Gaf domain
AMIS_31150	COG3706	GGDEF domain
AMIS_31150	COG5001	Diguanylate cyclase
AMIS_31150	COG4251	negative regulation of phosphorylation
AMIS_31260	COG0586	Pfam SNARE associated Golgi protein
AMIS_31270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_31280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_31350	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_31360	COG2085	NADP oxidoreductase coenzyme F420-dependent
AMIS_31380	COG2319	Wd-40 repeat
AMIS_31380	COG4249	Peptidase C14 caspase catalytic subunit p20
AMIS_31390	COG2124	cytochrome p450
AMIS_3150	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_31630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMIS_31640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMIS_31690	COG2197	response regulator
AMIS_31830	COG1063	alcohol dehydrogenase
AMIS_31900	COG0745	RESPONSE REGULATOR receiver
AMIS_31910	COG2205	protein histidine kinase activity
AMIS_31920	COG0840	transmembrane signaling receptor activity
AMIS_31960	COG3046	protein related to deoxyribodipyrimidine photolyase
AMIS_320	COG2353	YceI-like domain
AMIS_32000	COG4608	Belongs to the ABC transporter superfamily
AMIS_32040	COG0747	negative chemotaxis
AMIS_32100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMIS_32110	COG1228	amidohydrolase
AMIS_32120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMIS_32130	COG1522	sequence-specific DNA binding
AMIS_32150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMIS_32160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIS_32200	COG0438	transferase activity, transferring glycosyl groups
AMIS_32210	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_32230	COG1063	alcohol dehydrogenase
AMIS_32240	COG2124	cytochrome p450
AMIS_3230	COG1111	helicase
AMIS_3230	COG1205	dead DEAH box helicase
AMIS_32370	COG0277	FAD linked oxidase domain protein
AMIS_32390	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_3240	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_32420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIS_32440	COG2132	Multicopper oxidase
AMIS_32450	COG0475	glutathione-regulated potassium exporter activity
AMIS_32470	COG0395	ABC-type sugar transport system, permease component
AMIS_32490	COG1653	transport
AMIS_32550	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AMIS_32590	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_3260	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMIS_32600	COG1960	acyl-CoA dehydrogenase activity
AMIS_32800	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_32830	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_32840	COG1960	acyl-CoA dehydrogenase activity
AMIS_32850	COG1960	acyl-CoA dehydrogenase activity
AMIS_32890	COG0477	Major facilitator Superfamily
AMIS_3290	COG1754	DNA topoisomerase type I activity
AMIS_3290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMIS_32920	COG1271	oxidase subunit
AMIS_32960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMIS_33010	COG0789	Transcriptional regulator
AMIS_33060	COG1064	alcohol dehydrogenase
AMIS_3310	COG1309	transcriptional regulator
AMIS_33100	COG3321	synthase
AMIS_33100	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_33100	COG0604	alcohol dehydrogenase
AMIS_33150	COG1595	DNA-templated transcription, initiation
AMIS_33200	COG0589	response to stress
AMIS_33220	COG1295	ribonuclease BN
AMIS_33240	COG3795	YCII-related domain
AMIS_33290	COG0386	Belongs to the glutathione peroxidase family
AMIS_3330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMIS_33300	COG0321	lipoyl(octanoyl) transferase activity
AMIS_33330	COG1573	uracil-dna glycosylase
AMIS_33360	COG1982	Orn Lys Arg decarboxylase major
AMIS_33380	COG0765	amino acid transport
AMIS_3340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMIS_33500	COG2197	response regulator
AMIS_33540	COG2207	Transcriptional regulator
AMIS_33540	COG1609	Transcriptional regulator
AMIS_33570	COG0697	spore germination
AMIS_33580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_33620	COG4585	Histidine kinase
AMIS_33630	COG2197	response regulator
AMIS_33640	COG1136	(ABC) transporter
AMIS_33640	COG0577	efflux transmembrane transporter activity
AMIS_33670	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMIS_33680	COG0039	L-malate dehydrogenase activity
AMIS_33700	COG0022	dehydrogenase e1 component
AMIS_33720	COG1522	sequence-specific DNA binding
AMIS_33730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_33740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_33880	COG4191	Histidine kinase
AMIS_33890	COG1051	belongs to the nudix hydrolase family
AMIS_3390	COG1774	PSP1 C-terminal conserved region
AMIS_33970	COG0758	DNA mediated transformation
AMIS_34000	COG2814	Major facilitator Superfamily
AMIS_3410	COG4974	Belongs to the 'phage' integrase family
AMIS_34120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_34140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMIS_34150	COG5001	Diguanylate cyclase
AMIS_34150	COG3300	MHYT domain
AMIS_34160	COG3537	Alpha-1,2-mannosidase
AMIS_34210	COG2365	Tyrosine phosphatase family
AMIS_34220	COG2815	serine threonine protein kinase
AMIS_34220	COG0515	serine threonine protein kinase
AMIS_34230	COG2197	response regulator
AMIS_34430	COG0154	amidase activity
AMIS_34470	COG1609	Transcriptional regulator
AMIS_34540	COG0346	lactoylglutathione lyase activity
AMIS_34590	COG0477	Major facilitator Superfamily
AMIS_34600	COG3226	Transcriptional regulator
AMIS_34620	COG3347	Dehydrogenase
AMIS_34620	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_34630	COG1070	Carbohydrate kinase
AMIS_34640	COG0247	lactate metabolic process
AMIS_34650	COG1139	Iron-sulfur cluster binding protein
AMIS_34660	COG1556	Lactate utilization protein
AMIS_34690	COG2770	Histidine kinase
AMIS_34690	COG2208	phosphoserine phosphatase activity
AMIS_34700	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMIS_34710	COG2072	flavoprotein involved in K transport
AMIS_34750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMIS_34790	COG2197	response regulator
AMIS_34800	COG4585	Histidine kinase
AMIS_34810	COG1131	(ABC) transporter
AMIS_34840	COG2409	Drug exporters of the RND superfamily
AMIS_34910	COG0697	spore germination
AMIS_34960	COG3387	PFAM Glycoside hydrolase 15-related
AMIS_35020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMIS_35050	COG1609	Transcriptional regulator
AMIS_35090	COG0243	molybdopterin cofactor binding
AMIS_35160	COG1473	amidohydrolase
AMIS_35280	COG3795	YCII-related domain
AMIS_35290	COG4941	Belongs to the sigma-70 factor family
AMIS_3530	COG0693	protein deglycase activity
AMIS_35340	COG3629	intracellular signal transduction
AMIS_35340	COG3903	Transcriptional regulator
AMIS_35360	COG0670	Belongs to the BI1 family
AMIS_35400	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_35450	COG1132	(ABC) transporter
AMIS_35460	COG1132	(ABC) transporter
AMIS_35470	COG1120	ATPase activity
AMIS_35480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_35490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_3560	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AMIS_35610	COG1247	-acetyltransferase
AMIS_35630	COG0667	Aldo Keto reductase
AMIS_35660	COG1733	regulation of RNA biosynthetic process
AMIS_35700	COG1309	transcriptional regulator
AMIS_35710	COG2814	Major facilitator Superfamily
AMIS_35720	COG0726	polysaccharide deacetylase
AMIS_3580	COG1793	dna ligase
AMIS_3580	COG3285	dna ligase
AMIS_35840	COG0640	Transcriptional regulator
AMIS_35870	COG2197	response regulator
AMIS_35880	COG4585	Histidine kinase
AMIS_36040	COG3848	Pyruvate phosphate dikinase
AMIS_36040	COG0574	Belongs to the PEP-utilizing enzyme family
AMIS_36080	COG0745	RESPONSE REGULATOR receiver
AMIS_36130	COG1136	(ABC) transporter
AMIS_36130	COG0577	efflux transmembrane transporter activity
AMIS_36140	COG1136	(ABC) transporter
AMIS_36140	COG0577	efflux transmembrane transporter activity
AMIS_36170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_36200	COG4948	Mandelate Racemase Muconate Lactonizing
AMIS_36290	COG2801	Transposase and inactivated derivatives
AMIS_36290	COG3415	Transposase
AMIS_3640	COG0133	tryptophan synthase activity
AMIS_36400	COG0531	amino acid
AMIS_36480	COG1116	anion transmembrane transporter activity
AMIS_36490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_3650	COG0159	tryptophan synthase activity
AMIS_36500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_36520	COG1414	Transcriptional regulator
AMIS_36530	COG5001	Diguanylate cyclase
AMIS_36540	COG1309	transcriptional regulator
AMIS_36650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIS_36660	COG1414	Transcriptional regulator
AMIS_36670	COG3485	protocatechuate 3,4-dioxygenase
AMIS_36680	COG3485	protocatechuate 3,4-dioxygenase
AMIS_3670	COG1061	Type III restriction enzyme res subunit
AMIS_36700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMIS_36790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIS_36810	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMIS_36820	COG1073	alpha beta
AMIS_36950	COG2226	methyltransferase
AMIS_36990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMIS_3700	COG0546	phosphoglycolate phosphatase activity
AMIS_37020	COG2375	cellular response to nickel ion
AMIS_3710	COG1278	Cold shock
AMIS_37190	COG1960	acyl-CoA dehydrogenase activity
AMIS_3720	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AMIS_37210	COG1960	acyl-CoA dehydrogenase activity
AMIS_37250	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIS_37260	COG1609	Transcriptional regulator
AMIS_37290	COG0395	ABC-type sugar transport system, permease component
AMIS_37300	COG1501	Belongs to the glycosyl hydrolase 31 family
AMIS_37330	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AMIS_37350	COG1122	ATPase activity
AMIS_37380	COG0310	cobalt ion transport
AMIS_37430	COG0840	transmembrane signaling receptor activity
AMIS_37440	COG5002	protein histidine kinase activity
AMIS_37450	COG2204	response regulator
AMIS_37470	COG4952	isomerase
AMIS_37480	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIS_37490	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIS_3750	COG2723	6-phospho-beta-galactosidase activity
AMIS_37500	COG1129	ABC transporter
AMIS_37510	COG1879	ABC-type sugar transport system periplasmic component
AMIS_37550	COG0515	serine threonine protein kinase
AMIS_37550	COG2815	serine threonine protein kinase
AMIS_37600	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_37610	COG3842	ATPase activity
AMIS_37630	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMIS_37640	COG1177	transmembrane transport
AMIS_37650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMIS_37680	COG5002	protein histidine kinase activity
AMIS_37690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIS_37720	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_37730	COG2208	phosphoserine phosphatase activity
AMIS_37760	COG1175	transmembrane transport
AMIS_37780	COG1609	Transcriptional regulator
AMIS_3780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMIS_37820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_37830	COG0248	Ppx GppA phosphatase
AMIS_37840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMIS_37890	COG3191	aminopeptidase activity
AMIS_3790	COG2814	Major facilitator Superfamily
AMIS_37920	COG0442	prolyl-tRNA aminoacylation
AMIS_37930	COG0702	epimerase
AMIS_37940	COG1733	regulation of RNA biosynthetic process
AMIS_37970	COG3706	GGDEF domain
AMIS_37980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMIS_37990	COG1960	acyl-CoA dehydrogenase activity
AMIS_38050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_38110	COG1126	abc transporter atp-binding protein
AMIS_38190	COG0366	Alpha amylase catalytic
AMIS_3820	COG2252	PERMEase
AMIS_38280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_38290	COG2409	Drug exporters of the RND superfamily
AMIS_3830	COG1846	Transcriptional regulator
AMIS_38310	COG1132	(ABC) transporter
AMIS_38350	COG0778	Nitroreductase
AMIS_38370	COG0372	Belongs to the citrate synthase family
AMIS_3840	COG2814	Major facilitator Superfamily
AMIS_38500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIS_38510	COG2146	nitrite reductase [NAD(P)H] activity
AMIS_38520	COG2223	nitrite transmembrane transporter activity
AMIS_38560	COG1609	Transcriptional regulator
AMIS_38570	COG2223	nitrite transmembrane transporter activity
AMIS_38600	COG3706	GGDEF domain
AMIS_38620	COG1136	(ABC) transporter
AMIS_38620	COG0577	efflux transmembrane transporter activity
AMIS_38630	COG0577	efflux transmembrane transporter activity
AMIS_38670	COG0300	oxidoreductase activity
AMIS_38720	COG0300	oxidoreductase activity
AMIS_3880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AMIS_38800	COG2205	protein histidine kinase activity
AMIS_38840	COG1522	sequence-specific DNA binding
AMIS_38880	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMIS_38890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMIS_38900	COG2080	2 iron, 2 sulfur cluster binding
AMIS_38970	COG0583	DNA-binding transcription factor activity
AMIS_38980	COG1088	dTDP-glucose 4,6-dehydratase activity
AMIS_3900	COG0259	pyridoxamine-phosphate oxidase activity
AMIS_39060	COG0706	membrane insertase activity
AMIS_39070	COG2814	Major facilitator Superfamily
AMIS_39080	COG1846	Transcriptional regulator
AMIS_39100	COG2267	carboxylic ester hydrolase activity
AMIS_39110	COG1435	thymidine kinase activity
AMIS_39120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIS_39130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMIS_39160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMIS_3920	COG2017	converts alpha-aldose to the beta-anomer
AMIS_39200	COG2814	Major facilitator Superfamily
AMIS_39220	COG3851	Histidine kinase
AMIS_39230	COG2197	response regulator
AMIS_39270	COG0604	alcohol dehydrogenase
AMIS_39300	COG1672	PFAM Archaeal ATPase
AMIS_39300	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMIS_39380	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIS_39390	COG2226	methyltransferase
AMIS_39400	COG5001	Diguanylate cyclase
AMIS_39400	COG3300	MHYT domain
AMIS_39430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_39440	COG5002	protein histidine kinase activity
AMIS_39440	COG3447	MASE1 domain protein
AMIS_39440	COG5001	Diguanylate cyclase
AMIS_39540	COG1024	Enoyl-CoA hydratase
AMIS_39580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMIS_39590	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMIS_39600	COG5002	protein histidine kinase activity
AMIS_39610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_39640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_39740	COG1309	transcriptional regulator
AMIS_39750	COG3848	Pyruvate phosphate dikinase
AMIS_39750	COG0574	Belongs to the PEP-utilizing enzyme family
AMIS_39760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_39770	COG3708	Transcriptional regulator
AMIS_39770	COG2207	Transcriptional regulator
AMIS_3980	COG3842	ATPase activity
AMIS_39800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMIS_39810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIS_39820	COG2814	Major facilitator Superfamily
AMIS_39850	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIS_39870	COG0542	response to heat
AMIS_39920	COG1674	ftsk spoiiie
AMIS_39990	COG1902	pentaerythritol trinitrate reductase activity
AMIS_39990	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMIS_40	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMIS_40030	COG0277	FAD linked oxidase domain protein
AMIS_40030	COG0247	lactate metabolic process
AMIS_40040	COG2072	flavoprotein involved in K transport
AMIS_40120	COG1140	nitrate reductase beta subunit
AMIS_40130	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AMIS_40140	COG2181	nitrate reductase activity
AMIS_40200	COG0443	Heat shock 70 kDa protein
AMIS_40250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIS_40270	COG1960	acyl-CoA dehydrogenase activity
AMIS_40290	COG3119	arylsulfatase activity
AMIS_40300	COG5001	Diguanylate cyclase
AMIS_40300	COG3300	MHYT domain
AMIS_40320	COG2205	protein histidine kinase activity
AMIS_40330	COG0745	RESPONSE REGULATOR receiver
AMIS_40370	COG1846	Transcriptional regulator
AMIS_40370	COG1940	carbohydrate kinase activity
AMIS_40380	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMIS_4040	COG1388	LysM domain
AMIS_4040	COG1134	teichoic acid transport
AMIS_40410	COG0010	Belongs to the arginase family
AMIS_40450	COG1940	carbohydrate kinase activity
AMIS_40530	COG0596	Alpha beta hydrolase
AMIS_40550	COG0784	Response regulator, receiver
AMIS_40590	COG0714	Associated with various cellular activities
AMIS_4060	COG1309	transcriptional regulator
AMIS_40680	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIS_40700	COG0726	polysaccharide deacetylase
AMIS_40710	COG5002	protein histidine kinase activity
AMIS_40790	COG3226	Transcriptional regulator
AMIS_40860	COG5006	permease, DMT superfamily
AMIS_410	COG1716	ATPase activity
AMIS_410	COG1716	ATPase activity
AMIS_41070	COG0596	Alpha beta hydrolase
AMIS_41100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMIS_41110	COG0583	DNA-binding transcription factor activity
AMIS_41130	COG4974	Belongs to the 'phage' integrase family
AMIS_41160	COG2354	Protein conserved in bacteria
AMIS_41180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMIS_41180	COG0574	Belongs to the PEP-utilizing enzyme family
AMIS_41200	COG1131	(ABC) transporter
AMIS_41270	COG1131	(ABC) transporter
AMIS_41280	COG0842	Transport permease protein
AMIS_41290	COG4585	Histidine kinase
AMIS_41300	COG2197	response regulator
AMIS_41310	COG1191	sigma factor activity
AMIS_41350	COG1968	undecaprenyl-diphosphatase activity
AMIS_4140	COG0745	RESPONSE REGULATOR receiver
AMIS_41440	COG4585	Histidine kinase
AMIS_41450	COG2197	response regulator
AMIS_41510	COG2197	response regulator
AMIS_41560	COG2076	Multidrug Resistance protein
AMIS_41680	COG1764	response to oxidative stress
AMIS_41690	COG1846	Transcriptional regulator
AMIS_4170	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AMIS_41730	COG4702	Belongs to the UPF0303 family
AMIS_41780	COG2223	nitrite transmembrane transporter activity
AMIS_41880	COG0019	diaminopimelate decarboxylase activity
AMIS_41960	COG0242	peptide deformylase activity
AMIS_41980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMIS_420	COG1716	ATPase activity
AMIS_4200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMIS_42000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMIS_42000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMIS_42010	COG0667	Aldo Keto reductase
AMIS_42090	COG1960	acyl-CoA dehydrogenase activity
AMIS_4210	COG1086	Polysaccharide biosynthesis protein
AMIS_42110	COG1024	Enoyl-CoA hydratase
AMIS_42130	COG3599	regulation of cell shape
AMIS_42150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMIS_42210	COG0477	Major facilitator Superfamily
AMIS_42250	COG0346	lactoylglutathione lyase activity
AMIS_42260	COG0640	Transcriptional regulator
AMIS_42270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIS_42270	COG1017	nitric oxide dioxygenase activity
AMIS_42300	COG2197	response regulator
AMIS_42340	COG0596	Alpha beta hydrolase
AMIS_42340	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIS_42370	COG0110	maltose O-acetyltransferase activity
AMIS_42390	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_42430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMIS_42450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIS_42540	COG4106	trans-aconitate 2-methyltransferase activity
AMIS_42570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_42640	COG0583	DNA-binding transcription factor activity
AMIS_42650	COG0183	Belongs to the thiolase family
AMIS_42670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AMIS_42720	COG5002	protein histidine kinase activity
AMIS_42860	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_4290	COG2197	response regulator
AMIS_42900	COG2197	response regulator
AMIS_42920	COG0778	Nitroreductase
AMIS_42960	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AMIS_43000	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_43040	COG4566	intracellular signal transduction
AMIS_43050	COG0492	ferredoxin-NADP+ reductase activity
AMIS_43090	COG3012	SEC-C Motif Domain Protein
AMIS_4310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMIS_43100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMIS_43130	COG1063	alcohol dehydrogenase
AMIS_43160	COG1653	transport
AMIS_43190	COG1024	Enoyl-CoA hydratase
AMIS_4320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMIS_43230	COG1131	(ABC) transporter
AMIS_43270	COG2340	Cysteine-rich secretory protein family
AMIS_43280	COG1120	ATPase activity
AMIS_43290	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_43300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_43320	COG0840	transmembrane signaling receptor activity
AMIS_43320	COG5278	phosphoserine phosphatase activity
AMIS_43440	COG1309	transcriptional regulator
AMIS_43460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIS_43470	COG2151	metal-sulfur cluster biosynthetic enzyme
AMIS_43480	COG3396	Phenylacetate-CoA oxygenase
AMIS_43490	COG3460	Phenylacetate-CoA oxygenase
AMIS_43500	COG3396	Phenylacetate-CoA oxygenase
AMIS_43510	COG2030	dehydratase
AMIS_43510	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_43580	COG1902	pentaerythritol trinitrate reductase activity
AMIS_43640	COG1309	transcriptional regulator
AMIS_43740	COG3321	synthase
AMIS_43740	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_43740	COG0604	alcohol dehydrogenase
AMIS_43750	COG1476	TRANSCRIPTIONal
AMIS_43800	COG1846	Transcriptional regulator
AMIS_43840	COG0589	response to stress
AMIS_43920	COG0640	Transcriptional regulator
AMIS_43940	COG1064	alcohol dehydrogenase
AMIS_43980	COG3866	Pectate lyase
AMIS_44030	COG2072	flavoprotein involved in K transport
AMIS_44060	COG0738	Major facilitator superfamily
AMIS_44080	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_44090	COG1309	transcriptional regulator
AMIS_44110	COG0840	transmembrane signaling receptor activity
AMIS_44170	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIS_44180	COG0395	ABC-type sugar transport system, permease component
AMIS_44200	COG1653	transport
AMIS_44220	COG1609	Transcriptional regulator
AMIS_4430	COG2089	acid synthase
AMIS_44300	COG0110	maltose O-acetyltransferase activity
AMIS_44410	COG2837	iron assimilation
AMIS_44440	COG3903	Transcriptional regulator
AMIS_44440	COG3629	intracellular signal transduction
AMIS_4450	COG1216	Glycosyl transferase, family 2
AMIS_4460	COG5001	Diguanylate cyclase
AMIS_4460	COG3300	MHYT domain
AMIS_44610	COG1120	ATPase activity
AMIS_44670	COG0667	Aldo Keto reductase
AMIS_44740	COG1116	anion transmembrane transporter activity
AMIS_44770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMIS_44800	COG4585	Histidine kinase
AMIS_44810	COG2197	response regulator
AMIS_44880	COG4521	taurine ABC transporter
AMIS_44890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_4490	COG0596	Alpha beta hydrolase
AMIS_44960	COG3831	ATPase activity
AMIS_450	COG0768	penicillin binding
AMIS_4500	COG2119	membrane
AMIS_45020	COG0438	transferase activity, transferring glycosyl groups
AMIS_45070	COG2226	methyltransferase
AMIS_4530	COG0251	oxidation-reduction process
AMIS_45410	COG2226	methyltransferase
AMIS_45440	COG0438	transferase activity, transferring glycosyl groups
AMIS_45500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMIS_45520	COG3795	YCII-related domain
AMIS_45530	COG4941	Belongs to the sigma-70 factor family
AMIS_45590	COG1121	(ABC) transporter
AMIS_45600	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMIS_45620	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMIS_45640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMIS_45670	COG2080	2 iron, 2 sulfur cluster binding
AMIS_45680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMIS_45680	COG2010	Cytochrome c
AMIS_45740	COG1408	metallophosphoesterase
AMIS_45790	COG0402	S-adenosylhomocysteine deaminase activity
AMIS_45800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMIS_45910	COG4566	intracellular signal transduction
AMIS_460	COG0515	serine threonine protein kinase
AMIS_46040	COG3629	intracellular signal transduction
AMIS_46040	COG3903	Transcriptional regulator
AMIS_46090	COG2268	Band 7 protein
AMIS_46100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMIS_46110	COG1846	Transcriptional regulator
AMIS_46120	COG2814	Major facilitator Superfamily
AMIS_46150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMIS_4620	COG0586	Pfam SNARE associated Golgi protein
AMIS_46210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AMIS_46230	COG1672	PFAM Archaeal ATPase
AMIS_46230	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMIS_46260	COG0596	Alpha beta hydrolase
AMIS_46270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMIS_46300	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_46320	COG0596	Alpha beta hydrolase
AMIS_46330	COG0596	Alpha beta hydrolase
AMIS_46390	COG2197	response regulator
AMIS_46400	COG4585	Histidine kinase
AMIS_46420	COG1131	(ABC) transporter
AMIS_4650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMIS_46510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIS_46520	COG0800	Aldolase
AMIS_46530	COG0246	Mannitol dehydrogenase
AMIS_46540	COG1904	glucuronate isomerase
AMIS_46550	COG2721	sulfolactate sulfo-lyase activity
AMIS_4660	COG1609	Transcriptional regulator
AMIS_46620	COG0477	Major facilitator Superfamily
AMIS_46630	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AMIS_46640	COG0076	glutamate decarboxylase activity
AMIS_46720	COG1760	l-serine dehydratase
AMIS_46730	COG0509	glycine decarboxylation via glycine cleavage system
AMIS_46740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMIS_46810	COG2070	2-Nitropropane dioxygenase
AMIS_46830	COG1136	(ABC) transporter
AMIS_46890	COG3940	Belongs to the glycosyl hydrolase 43 family
AMIS_46910	COG0494	nUDIX hydrolase
AMIS_46990	COG0596	Alpha beta hydrolase
AMIS_470	COG0515	serine threonine protein kinase
AMIS_470	COG2815	serine threonine protein kinase
AMIS_47030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMIS_47060	COG0596	Alpha beta hydrolase
AMIS_47070	COG2197	response regulator
AMIS_47080	COG4585	Histidine kinase
AMIS_47100	COG1131	(ABC) transporter
AMIS_47150	COG1609	Transcriptional regulator
AMIS_47160	COG1609	Transcriptional regulator
AMIS_47270	COG0069	glutamate synthase activity
AMIS_4730	COG1309	transcriptional regulator
AMIS_47310	COG2205	protein histidine kinase activity
AMIS_47330	COG3546	catalase activity
AMIS_47340	COG1914	H( )-stimulated, divalent metal cation uptake system
AMIS_47350	COG2197	response regulator
AMIS_47360	COG2205	protein histidine kinase activity
AMIS_47380	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIS_47390	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_4740	COG1131	(ABC) transporter
AMIS_4750	COG3559	Exporter of polyketide antibiotics
AMIS_47500	COG0667	Aldo Keto reductase
AMIS_47540	COG0463	Glycosyl transferase, family 2
AMIS_47560	COG3973	AAA domain
AMIS_47580	COG1607	acyl-coa hydrolase
AMIS_47590	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMIS_4760	COG0025	NhaP-type Na H and K H
AMIS_47600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMIS_47610	COG1228	amidohydrolase
AMIS_47620	COG0604	alcohol dehydrogenase
AMIS_47670	COG0583	DNA-binding transcription factor activity
AMIS_47700	COG1960	acyl-CoA dehydrogenase activity
AMIS_47710	COG2197	response regulator
AMIS_47720	COG4585	Histidine kinase
AMIS_47730	COG1136	(ABC) transporter
AMIS_47750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMIS_47760	COG1716	ATPase activity
AMIS_47760	COG5001	Diguanylate cyclase
AMIS_4780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMIS_47800	COG3706	GGDEF domain
AMIS_47850	COG2223	nitrite transmembrane transporter activity
AMIS_47860	COG5002	protein histidine kinase activity
AMIS_47860	COG5001	Diguanylate cyclase
AMIS_47860	COG3447	MASE1 domain protein
AMIS_47950	COG1063	alcohol dehydrogenase
AMIS_48040	COG0667	Aldo Keto reductase
AMIS_48050	COG0789	Transcriptional regulator
AMIS_48170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AMIS_48230	COG3022	response to hydroperoxide
AMIS_48280	COG0706	membrane insertase activity
AMIS_4830	COG1088	dTDP-glucose 4,6-dehydratase activity
AMIS_48310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMIS_48360	COG2124	cytochrome p450
AMIS_48380	COG0531	amino acid
AMIS_48400	COG0515	serine threonine protein kinase
AMIS_48450	COG1072	(Pantothenic acid kinase))
AMIS_48460	COG1408	metallophosphoesterase
AMIS_4850	COG2814	Major facilitator Superfamily
AMIS_48500	COG1132	(ABC) transporter
AMIS_48510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIS_48550	COG0673	inositol 2-dehydrogenase activity
AMIS_48590	COG1082	Xylose isomerase domain protein TIM barrel
AMIS_4860	COG0673	inositol 2-dehydrogenase activity
AMIS_48610	COG3962	Belongs to the TPP enzyme family
AMIS_48620	COG3718	enzyme involved in inositol metabolism
AMIS_48660	COG0861	Integral membrane protein TerC family
AMIS_48700	COG0577	efflux transmembrane transporter activity
AMIS_48700	COG1136	(ABC) transporter
AMIS_48710	COG1136	(ABC) transporter
AMIS_48730	COG2205	protein histidine kinase activity
AMIS_48740	COG0745	RESPONSE REGULATOR receiver
AMIS_48780	COG2197	response regulator
AMIS_48800	COG0406	alpha-ribazole phosphatase activity
AMIS_48840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMIS_48890	COG1309	transcriptional regulator
AMIS_48960	COG0515	serine threonine protein kinase
AMIS_49000	COG2197	response regulator
AMIS_49010	COG4585	Histidine kinase
AMIS_49050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_49080	COG1132	(ABC) transporter
AMIS_49090	COG1309	transcriptional regulator
AMIS_49140	COG0166	Belongs to the GPI family
AMIS_49170	COG0395	ABC-type sugar transport system, permease component
AMIS_49190	COG1653	transport
AMIS_49390	COG4214	carbohydrate transport
AMIS_4940	COG3268	Saccharopine dehydrogenase
AMIS_49410	COG4213	ABC transporter substrate-binding protein
AMIS_49430	COG1620	l-lactate permease
AMIS_49440	COG2080	2 iron, 2 sulfur cluster binding
AMIS_49440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMIS_49460	COG1271	oxidase subunit
AMIS_49470	COG1294	oxidase, subunit
AMIS_49480	COG4988	ABC transporter
AMIS_49490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AMIS_4950	COG1388	LysM domain
AMIS_49590	COG5001	Diguanylate cyclase
AMIS_49590	COG5002	protein histidine kinase activity
AMIS_49590	COG3447	MASE1 domain protein
AMIS_4970	COG0583	DNA-binding transcription factor activity
AMIS_49730	COG0456	acetyltransferase
AMIS_49750	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_49820	COG4585	Histidine kinase
AMIS_49830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMIS_49900	COG1309	transcriptional regulator
AMIS_49940	COG0745	RESPONSE REGULATOR receiver
AMIS_50	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AMIS_50000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMIS_50010	COG0791	NLP P60 protein
AMIS_50010	COG3103	Sh3 type 3 domain protein
AMIS_50010	COG1388	LysM domain
AMIS_50020	COG0501	Belongs to the peptidase M48B family
AMIS_50040	COG1271	oxidase subunit
AMIS_50050	COG1294	oxidase, subunit
AMIS_50060	COG4988	ABC transporter
AMIS_50070	COG0183	Belongs to the thiolase family
AMIS_50100	COG0859	PFAM glycosyl transferase family 9
AMIS_50110	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_50120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMIS_50120	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMIS_50130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMIS_50140	COG0438	transferase activity, transferring glycosyl groups
AMIS_50160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMIS_50180	COG2192	nodulation
AMIS_50230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_50270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMIS_50290	COG0477	Major facilitator Superfamily
AMIS_50360	COG1024	Enoyl-CoA hydratase
AMIS_50380	COG3425	synthase
AMIS_50390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIS_5040	COG4251	negative regulation of phosphorylation
AMIS_50410	COG4221	oxidoreductase activity
AMIS_50410	COG3321	synthase
AMIS_50410	COG0300	oxidoreductase activity
AMIS_50410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIS_50420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMIS_50440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIS_50450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMIS_50470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_50490	COG1960	acyl-CoA dehydrogenase activity
AMIS_5060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMIS_50650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMIS_50680	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_50690	COG1132	(ABC) transporter
AMIS_50710	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AMIS_50720	COG0431	NADPH-dependent FMN reductase
AMIS_50750	COG1309	transcriptional regulator
AMIS_50760	COG0477	Major facilitator Superfamily
AMIS_50780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIS_5080	COG1525	nuclease
AMIS_5080	COG4085	toxin activity
AMIS_5080	COG0737	Belongs to the 5'-nucleotidase family
AMIS_50800	COG0326	Molecular chaperone. Has ATPase activity
AMIS_50860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMIS_50900	COG0438	transferase activity, transferring glycosyl groups
AMIS_50940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIS_50960	COG0514	ATP-dependent DNA helicase (RecQ)
AMIS_50970	COG2353	YceI-like domain
AMIS_5100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMIS_51000	COG0574	Belongs to the PEP-utilizing enzyme family
AMIS_51000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMIS_51020	COG0277	FAD linked oxidase domain protein
AMIS_51030	COG0277	FAD linked oxidase domain protein
AMIS_51040	COG0247	lactate metabolic process
AMIS_51080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMIS_51090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_5110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMIS_51100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMIS_51110	COG4213	ABC transporter substrate-binding protein
AMIS_51120	COG0395	ABC-type sugar transport system, permease component
AMIS_51140	COG1653	transport
AMIS_51170	COG0366	Alpha amylase catalytic
AMIS_51180	COG1403	HNH endonuclease
AMIS_51190	COG0009	L-threonylcarbamoyladenylate synthase
AMIS_5120	COG2205	protein histidine kinase activity
AMIS_51220	COG4733	cellulase activity
AMIS_51220	COG5297	Belongs to the glycosyl hydrolase family 6
AMIS_51250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMIS_51260	COG1653	transport
AMIS_51270	COG1175	transmembrane transport
AMIS_51280	COG0395	ABC-type sugar transport system, permease component
AMIS_51290	COG1136	(ABC) transporter
AMIS_51290	COG0577	efflux transmembrane transporter activity
AMIS_5130	COG0745	RESPONSE REGULATOR receiver
AMIS_51300	COG1136	(ABC) transporter
AMIS_51350	COG2205	protein histidine kinase activity
AMIS_51360	COG0745	RESPONSE REGULATOR receiver
AMIS_51490	COG1174	glycine betaine transport
AMIS_5150	COG1193	negative regulation of DNA recombination
AMIS_51500	COG1174	glycine betaine transport
AMIS_51550	COG1609	Transcriptional regulator
AMIS_51560	COG2986	histidine ammonia-lyase
AMIS_51590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIS_51650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIS_51680	COG1309	transcriptional regulator
AMIS_51700	COG2205	protein histidine kinase activity
AMIS_51710	COG0745	RESPONSE REGULATOR receiver
AMIS_51740	COG0745	RESPONSE REGULATOR receiver
AMIS_51750	COG2205	protein histidine kinase activity
AMIS_51790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMIS_5180	COG0745	RESPONSE REGULATOR receiver
AMIS_51800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMIS_51840	COG1716	ATPase activity
AMIS_5190	COG4251	negative regulation of phosphorylation
AMIS_51910	COG4867	von Willebrand factor, type A
AMIS_51920	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AMIS_51930	COG0384	phenazine biosynthesis protein PhzF
AMIS_51940	COG3467	pyridoxamine 5'-phosphate
AMIS_51950	COG0488	(ABC) transporter
AMIS_51980	COG1649	PFAM Uncharacterised BCR, COG1649
AMIS_51990	COG0297	glycogen (starch) synthase activity
AMIS_5200	COG0784	Response regulator, receiver
AMIS_52000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMIS_5210	COG0483	inositol monophosphate 1-phosphatase activity
AMIS_52120	COG2501	S4 domain
AMIS_52150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMIS_52160	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_5220	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_52200	COG4214	carbohydrate transport
AMIS_52210	COG1129	ABC transporter
AMIS_52220	COG4213	ABC transporter substrate-binding protein
AMIS_52230	COG2160	L-arabinose isomerase activity
AMIS_52240	COG1609	Transcriptional regulator
AMIS_52340	COG0577	efflux transmembrane transporter activity
AMIS_52340	COG1136	(ABC) transporter
AMIS_52350	COG1136	(ABC) transporter
AMIS_52350	COG0577	efflux transmembrane transporter activity
AMIS_52360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMIS_52380	COG2340	Cysteine-rich secretory protein family
AMIS_52430	COG0840	transmembrane signaling receptor activity
AMIS_52450	COG2201	protein-glutamate methylesterase activity
AMIS_52460	COG3706	GGDEF domain
AMIS_52460	COG0745	RESPONSE REGULATOR receiver
AMIS_52480	COG1136	(ABC) transporter
AMIS_52480	COG0577	efflux transmembrane transporter activity
AMIS_52490	COG0577	efflux transmembrane transporter activity
AMIS_52490	COG1136	(ABC) transporter
AMIS_52510	COG2197	response regulator
AMIS_52520	COG3551	Protein conserved in bacteria
AMIS_52540	COG0583	DNA-binding transcription factor activity
AMIS_5260	COG0515	serine threonine protein kinase
AMIS_5260	COG2815	serine threonine protein kinase
AMIS_52610	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMIS_52670	COG0671	phosphoesterase, PA-phosphatase related
AMIS_52680	COG5278	phosphoserine phosphatase activity
AMIS_52680	COG0840	transmembrane signaling receptor activity
AMIS_52700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMIS_52750	COG1280	lysine exporter protein (LysE YggA)
AMIS_52800	COG3842	ATPase activity
AMIS_52820	COG3551	Protein conserved in bacteria
AMIS_52860	COG2197	response regulator
AMIS_52870	COG1120	ATPase activity
AMIS_52880	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_52890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_52900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMIS_52920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_52930	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_52940	COG1120	ATPase activity
AMIS_52950	COG0840	transmembrane signaling receptor activity
AMIS_52960	COG0579	oxidoreductase
AMIS_530	COG2181	nitrate reductase activity
AMIS_530	COG0247	lactate metabolic process
AMIS_5300	COG0514	ATP-dependent DNA helicase (RecQ)
AMIS_53000	COG0745	RESPONSE REGULATOR receiver
AMIS_53020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIS_53020	COG1017	nitric oxide dioxygenase activity
AMIS_53130	COG3706	GGDEF domain
AMIS_53130	COG0745	RESPONSE REGULATOR receiver
AMIS_53190	COG0577	efflux transmembrane transporter activity
AMIS_53190	COG1136	(ABC) transporter
AMIS_53200	COG4585	Histidine kinase
AMIS_53240	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMIS_53250	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_53270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIS_53290	COG0515	serine threonine protein kinase
AMIS_53330	COG3903	Transcriptional regulator
AMIS_53330	COG3629	intracellular signal transduction
AMIS_53400	COG1022	Amp-dependent synthetase and ligase
AMIS_53450	COG0546	phosphoglycolate phosphatase activity
AMIS_53490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMIS_53510	COG2378	regulation of single-species biofilm formation
AMIS_53570	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMIS_53580	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMIS_53590	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMIS_5360	COG0513	Belongs to the DEAD box helicase family
AMIS_53610	COG4122	O-methyltransferase activity
AMIS_53630	COG1222	aaa ATPase
AMIS_53670	COG0517	IMP dehydrogenase activity
AMIS_53670	COG1994	Peptidase M50
AMIS_53690	COG2197	response regulator
AMIS_53710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIS_53730	COG0667	Aldo Keto reductase
AMIS_53740	COG1136	(ABC) transporter
AMIS_53740	COG0577	efflux transmembrane transporter activity
AMIS_53750	COG1136	(ABC) transporter
AMIS_53750	COG0577	efflux transmembrane transporter activity
AMIS_53850	COG2197	response regulator
AMIS_53860	COG3415	Transposase
AMIS_53860	COG2801	Transposase and inactivated derivatives
AMIS_53880	COG4585	Histidine kinase
AMIS_53890	COG2197	response regulator
AMIS_53910	COG0215	cysteine-tRNA ligase activity
AMIS_53940	COG0588	phosphoglycerate mutase activity
AMIS_53950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_53960	COG0667	Aldo Keto reductase
AMIS_53990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_54020	COG0542	response to heat
AMIS_54130	COG0745	RESPONSE REGULATOR receiver
AMIS_54150	COG0653	protein targeting
AMIS_54170	COG0673	inositol 2-dehydrogenase activity
AMIS_54180	COG0463	Glycosyl transferase, family 2
AMIS_54210	COG2201	protein-glutamate methylesterase activity
AMIS_54240	COG1191	sigma factor activity
AMIS_54290	COG1797	cobyrinic acid a,c-diamide synthase activity
AMIS_54320	COG1070	Carbohydrate kinase
AMIS_54370	COG0708	Exodeoxyribonuclease III
AMIS_54430	COG1643	Atp-dependent helicase
AMIS_54440	COG1316	TRANSCRIPTIONal
AMIS_54450	COG0784	Response regulator, receiver
AMIS_54460	COG4251	negative regulation of phosphorylation
AMIS_54510	COG1940	carbohydrate kinase activity
AMIS_54580	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMIS_54590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIS_54620	COG2183	response to ionizing radiation
AMIS_54650	COG4115	mRNA cleavage
AMIS_5470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMIS_54730	COG5297	Belongs to the glycosyl hydrolase family 6
AMIS_54740	COG5001	Diguanylate cyclase
AMIS_54760	COG1960	acyl-CoA dehydrogenase activity
AMIS_54790	COG0584	glycerophosphoryl diester phosphodiesterase
AMIS_5480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMIS_54850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_54860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMIS_54870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIS_54890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_54910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_54920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMIS_54960	COG5001	Diguanylate cyclase
AMIS_54980	COG0515	serine threonine protein kinase
AMIS_5500	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMIS_55000	COG4977	sequence-specific DNA binding
AMIS_55020	COG1609	Transcriptional regulator
AMIS_55040	COG4106	trans-aconitate 2-methyltransferase activity
AMIS_55080	COG3866	Pectate lyase
AMIS_55100	COG0673	inositol 2-dehydrogenase activity
AMIS_55110	COG0246	Mannitol dehydrogenase
AMIS_55120	COG1904	glucuronate isomerase
AMIS_55130	COG0673	inositol 2-dehydrogenase activity
AMIS_55140	COG1609	Transcriptional regulator
AMIS_55160	COG1175	transmembrane transport
AMIS_55170	COG0395	ABC-type sugar transport system, permease component
AMIS_55230	COG1464	Belongs to the NlpA lipoprotein family
AMIS_55240	COG2011	ABC-type metal ion transport system permease component
AMIS_55250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMIS_55260	COG2197	response regulator
AMIS_55270	COG4585	Histidine kinase
AMIS_55320	COG1486	melibiose metabolic process
AMIS_55370	COG0840	transmembrane signaling receptor activity
AMIS_55380	COG0477	Major facilitator Superfamily
AMIS_55420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIS_55420	COG1017	nitric oxide dioxygenase activity
AMIS_55450	COG0840	transmembrane signaling receptor activity
AMIS_55480	COG0395	ABC-type sugar transport system, permease component
AMIS_55490	COG0395	ABC-type sugar transport system, permease component
AMIS_5550	COG0076	glutamate decarboxylase activity
AMIS_55500	COG1609	Transcriptional regulator
AMIS_55580	COG2409	Drug exporters of the RND superfamily
AMIS_55620	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AMIS_55650	COG2160	L-arabinose isomerase activity
AMIS_55660	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIS_55670	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIS_55690	COG1879	ABC-type sugar transport system periplasmic component
AMIS_5570	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIS_55700	COG1609	Transcriptional regulator
AMIS_55720	COG0235	Class ii aldolase
AMIS_55780	COG2130	NADP-dependent
AMIS_55790	COG1309	transcriptional regulator
AMIS_5580	COG0181	hydroxymethylbilane synthase activity
AMIS_55800	COG0569	domain protein
AMIS_55850	COG0840	transmembrane signaling receptor activity
AMIS_55860	COG1316	TRANSCRIPTIONal
AMIS_55910	COG1131	(ABC) transporter
AMIS_56060	COG0583	DNA-binding transcription factor activity
AMIS_56070	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_56090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIS_56120	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_56130	COG1414	Transcriptional regulator
AMIS_56150	COG0656	L-ascorbic acid biosynthetic process
AMIS_56170	COG3458	cephalosporin-C deacetylase activity
AMIS_56180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMIS_5620	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIS_56230	COG1461	Dihydroxyacetone kinase
AMIS_56240	COG2376	Dihydroxyacetone kinase
AMIS_56250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMIS_56250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMIS_56250	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AMIS_56270	COG0183	Belongs to the thiolase family
AMIS_56280	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_5630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMIS_56300	COG1960	acyl-CoA dehydrogenase activity
AMIS_56310	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_56320	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_56350	COG3634	alkyl hydroperoxide reductase activity
AMIS_56360	COG1396	sequence-specific DNA binding
AMIS_56370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMIS_5640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIS_56420	COG3940	Belongs to the glycosyl hydrolase 43 family
AMIS_56430	COG1959	2 iron, 2 sulfur cluster binding
AMIS_56450	COG2072	flavoprotein involved in K transport
AMIS_5650	COG0839	Belongs to the complex I subunit 6 family
AMIS_56530	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_56550	COG0154	amidase activity
AMIS_56590	COG4608	Belongs to the ABC transporter superfamily
AMIS_5660	COG0713	ATP synthesis coupled electron transport
AMIS_56600	COG0444	Belongs to the ABC transporter superfamily
AMIS_56610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIS_56620	COG0601	transmembrane transport
AMIS_56650	COG1309	transcriptional regulator
AMIS_56660	COG0477	Major facilitator Superfamily
AMIS_56680	COG1086	Polysaccharide biosynthesis protein
AMIS_56690	COG0489	protein tyrosine kinase activity
AMIS_5670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMIS_56710	COG3959	Transketolase, thiamine diphosphate binding domain
AMIS_56720	COG3958	Transketolase
AMIS_56740	COG1215	transferase activity, transferring glycosyl groups
AMIS_56750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMIS_56760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMIS_56790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMIS_5690	COG1007	ATP synthesis coupled electron transport
AMIS_56950	COG1252	NADH dehydrogenase
AMIS_56960	COG1435	thymidine kinase activity
AMIS_57030	COG2301	Belongs to the HpcH HpaI aldolase family
AMIS_57040	COG1960	acyl-CoA dehydrogenase activity
AMIS_57060	COG0183	Belongs to the thiolase family
AMIS_57150	COG1414	Transcriptional regulator
AMIS_57170	COG1960	acyl-CoA dehydrogenase activity
AMIS_57180	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_5720	COG0501	Belongs to the peptidase M48B family
AMIS_57210	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_5730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_57300	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_57340	COG0411	ABC transporter
AMIS_57420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMIS_57430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIS_57480	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_57490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIS_57500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMIS_57510	COG1335	isochorismatase
AMIS_57540	COG0471	metal ion transport
AMIS_57590	COG1595	DNA-templated transcription, initiation
AMIS_57680	COG1609	Transcriptional regulator
AMIS_57780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMIS_57790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMIS_57790	COG1213	nucleotidyl transferase
AMIS_57850	COG1937	Protein conserved in bacteria
AMIS_57890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMIS_5790	COG1666	GTP binding
AMIS_57900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIS_57950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMIS_57960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMIS_57980	COG1414	Transcriptional regulator
AMIS_57990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMIS_58090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMIS_58110	COG0489	protein tyrosine kinase activity
AMIS_58190	COG1063	alcohol dehydrogenase
AMIS_58250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMIS_58270	COG1086	Polysaccharide biosynthesis protein
AMIS_58280	COG0438	transferase activity, transferring glycosyl groups
AMIS_5830	COG3300	MHYT domain
AMIS_5830	COG5001	Diguanylate cyclase
AMIS_58300	COG2197	response regulator
AMIS_58350	COG0477	Major facilitator Superfamily
AMIS_58380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMIS_5840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMIS_58450	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_58480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMIS_58490	COG4565	transcriptional regulatory protein
AMIS_5850	COG2030	dehydratase
AMIS_58500	COG3290	protein histidine kinase activity
AMIS_58510	COG1301	dicarboxylic acid transport
AMIS_58570	COG0569	domain protein
AMIS_58580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMIS_58640	COG0542	response to heat
AMIS_58660	COG2936	dipeptidyl-peptidase activity
AMIS_58690	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMIS_5870	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMIS_58740	COG1216	Glycosyl transferase, family 2
AMIS_58750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMIS_58880	COG0667	Aldo Keto reductase
AMIS_5890	COG0081	regulation of translation
AMIS_58970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMIS_590	COG0717	Belongs to the dCTP deaminase family
AMIS_59060	COG1921	L-seryl-tRNASec selenium transferase activity
AMIS_59080	COG0709	Synthesizes selenophosphate from selenide and ATP
AMIS_59100	COG2318	DinB family
AMIS_59130	COG0437	4 iron, 4 sulfur cluster binding
AMIS_59140	COG0243	molybdopterin cofactor binding
AMIS_59140	COG3383	formate dehydrogenase (NAD+) activity
AMIS_59150	COG0243	molybdopterin cofactor binding
AMIS_59180	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_59290	COG1309	transcriptional regulator
AMIS_5930	COG0222	ribosome binding
AMIS_59310	COG4977	sequence-specific DNA binding
AMIS_5940	COG0085	RNA polymerase activity
AMIS_5950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMIS_59520	COG0840	transmembrane signaling receptor activity
AMIS_59590	COG2188	Transcriptional regulator
AMIS_59600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIS_59700	COG0411	ABC transporter
AMIS_59740	COG1846	Transcriptional regulator
AMIS_59760	COG1309	transcriptional regulator
AMIS_59770	COG4221	oxidoreductase activity
AMIS_59780	COG2226	methyltransferase
AMIS_5980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMIS_59800	COG0024	Methionine aminopeptidase
AMIS_59820	COG3104	oligopeptide transport
AMIS_59860	COG4948	Mandelate Racemase Muconate Lactonizing
AMIS_59870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMIS_59880	COG0395	ABC-type sugar transport system, permease component
AMIS_59890	COG1175	transmembrane transport
AMIS_5990	COG0049	tRNA binding
AMIS_59900	COG1653	transport
AMIS_59910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMIS_59930	COG1414	Transcriptional regulator
AMIS_59950	COG4124	Belongs to the glycosyl hydrolase 26 family
AMIS_59980	COG1175	transmembrane transport
AMIS_6000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMIS_60070	COG0604	alcohol dehydrogenase
AMIS_60070	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_60070	COG3321	synthase
AMIS_60080	COG0641	radical SAM
AMIS_6010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMIS_60100	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AMIS_6020	COG0051	transcription antitermination factor activity, RNA binding
AMIS_60200	COG0210	DNA helicase
AMIS_60210	COG0515	serine threonine protein kinase
AMIS_60220	COG0210	DNA helicase
AMIS_60260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMIS_60260	COG0515	serine threonine protein kinase
AMIS_6030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMIS_60330	COG4941	Belongs to the sigma-70 factor family
AMIS_60340	COG0738	Major facilitator superfamily
AMIS_60350	COG1160	GTP binding
AMIS_60360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMIS_60390	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIS_6040	COG0088	Forms part of the polypeptide exit tunnel
AMIS_60400	COG2814	Major facilitator Superfamily
AMIS_60470	COG3655	Transcriptional regulator
AMIS_6050	COG0089	rRNA binding
AMIS_6060	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMIS_60610	COG0183	Belongs to the thiolase family
AMIS_60620	COG1024	Enoyl-CoA hydratase
AMIS_60620	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIS_60670	COG1132	(ABC) transporter
AMIS_60680	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_60690	COG3300	MHYT domain
AMIS_60690	COG5001	Diguanylate cyclase
AMIS_6070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMIS_60730	COG2814	Major facilitator Superfamily
AMIS_60770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMIS_60780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMIS_60790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIS_6080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMIS_60800	COG2226	methyltransferase
AMIS_60890	COG0504	CTP synthase activity
AMIS_6090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMIS_60970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMIS_6100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMIS_61020	COG0840	transmembrane signaling receptor activity
AMIS_61040	COG0647	UMP catabolic process
AMIS_61080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMIS_61090	COG2326	polyphosphate kinase activity
AMIS_6110	COG0255	Belongs to the universal ribosomal protein uL29 family
AMIS_61100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMIS_61110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMIS_61120	COG1063	alcohol dehydrogenase
AMIS_61130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMIS_61130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMIS_61140	COG2213	PTS system mannitol-specific
AMIS_61140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMIS_61150	COG2213	PTS system mannitol-specific
AMIS_61150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMIS_61160	COG1105	Belongs to the carbohydrate kinase PfkB family
AMIS_61170	COG1349	DNA-binding transcription factor activity
AMIS_61190	COG0563	adenylate kinase activity
AMIS_6120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMIS_61270	COG2094	Belongs to the DNA glycosylase MPG family
AMIS_61290	COG3973	AAA domain
AMIS_6130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMIS_61340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMIS_61350	COG0406	alpha-ribazole phosphatase activity
AMIS_61370	COG0730	response to heat
AMIS_6140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMIS_61400	COG1802	Transcriptional regulator
AMIS_61440	COG3833	ABC-type maltose transport systems, permease component
AMIS_61450	COG1175	transmembrane transport
AMIS_61480	COG1609	Transcriptional regulator
AMIS_61490	COG0165	Argininosuccinate lyase
AMIS_6150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMIS_61500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_61510	COG0137	argininosuccinate synthase activity
AMIS_61540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMIS_61550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMIS_61560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMIS_61570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMIS_61580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMIS_6160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMIS_61620	COG1733	regulation of RNA biosynthetic process
AMIS_61640	COG3572	ergothioneine biosynthetic process
AMIS_61650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMIS_61670	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AMIS_6170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMIS_61700	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AMIS_61710	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AMIS_61720	COG0714	Associated with various cellular activities
AMIS_61730	COG3831	ATPase activity
AMIS_6180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMIS_61810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIS_61810	COG0072	phenylalanine-tRNA ligase activity
AMIS_61820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMIS_61830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMIS_61840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMIS_61850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMIS_61860	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMIS_61880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMIS_61890	COG0140	phosphoribosyl-ATP diphosphatase activity
AMIS_6190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMIS_61910	COG0765	amino acid transport
AMIS_61930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMIS_61940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIS_61940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIS_61990	COG0745	RESPONSE REGULATOR receiver
AMIS_6200	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMIS_62030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMIS_62040	COG0242	peptide deformylase activity
AMIS_62060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMIS_62080	COG1758	RNA polymerase activity
AMIS_62090	COG0194	GDP metabolic process
AMIS_6210	COG1841	ribosomal large subunit assembly
AMIS_62110	COG0284	orotidine-5'-phosphate decarboxylase activity
AMIS_62120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMIS_62130	COG0167	dihydroorotate dehydrogenase activity
AMIS_62150	COG0505	Belongs to the CarA family
AMIS_62160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIS_62170	COG0540	Belongs to the ATCase OTCase family
AMIS_62180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AMIS_6220	COG0200	Binds to the 23S rRNA
AMIS_62200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMIS_62210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMIS_62220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMIS_62230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMIS_62240	COG0542	response to heat
AMIS_62250	COG0726	polysaccharide deacetylase
AMIS_62260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMIS_62270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMIS_62280	COG2814	Major facilitator Superfamily
AMIS_62290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMIS_62310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMIS_62320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMIS_62330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMIS_6240	COG0563	adenylate kinase activity
AMIS_62420	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMIS_62470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMIS_62480	COG0395	ABC-type sugar transport system, permease component
AMIS_62490	COG1175	transmembrane transport
AMIS_62520	COG3964	amidohydrolase
AMIS_62540	COG0515	serine threonine protein kinase
AMIS_62550	COG2755	lipolytic protein G-D-S-L family
AMIS_62550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMIS_62560	COG0831	urea catabolic process
AMIS_62570	COG0832	Belongs to the urease beta subunit family
AMIS_62600	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMIS_62610	COG0829	nickel cation binding
AMIS_62650	COG0515	serine threonine protein kinase
AMIS_62660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMIS_62660	COG0189	ligase activity
AMIS_62670	COG4242	Belongs to the peptidase S51 family
AMIS_6270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMIS_62710	COG0124	histidyl-tRNA synthetase
AMIS_62750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMIS_62760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMIS_62790	COG1862	Preprotein translocase
AMIS_6280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMIS_62800	COG2255	four-way junction helicase activity
AMIS_62810	COG0632	four-way junction helicase activity
AMIS_62820	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMIS_62840	COG0217	transcriptional regulatory protein
AMIS_62850	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AMIS_62860	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AMIS_62880	COG0438	transferase activity, transferring glycosyl groups
AMIS_62890	COG1560	Kdo2-lipid A biosynthetic process
AMIS_6290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMIS_62960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMIS_62990	COG2205	protein histidine kinase activity
AMIS_630	COG2770	Histidine kinase
AMIS_630	COG2208	phosphoserine phosphatase activity
AMIS_6300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMIS_63020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMIS_63040	COG0667	Aldo Keto reductase
AMIS_63060	COG1278	Cold shock
AMIS_6310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMIS_63140	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIS_63160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_63170	COG0514	ATP-dependent DNA helicase (RecQ)
AMIS_63250	COG0683	leucine binding
AMIS_63260	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMIS_6330	COG0203	ribosomal protein L17
AMIS_63320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIS_63330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMIS_63330	COG1672	PFAM Archaeal ATPase
AMIS_63340	COG4106	trans-aconitate 2-methyltransferase activity
AMIS_6340	COG0101	tRNA pseudouridine synthase activity
AMIS_63410	COG2197	response regulator
AMIS_63450	COG0297	glycogen (starch) synthase activity
AMIS_63640	COG0542	response to heat
AMIS_6370	COG0488	(ABC) transporter
AMIS_63700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMIS_63720	COG4266	Belongs to the allantoicase family
AMIS_63730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIS_6380	COG0352	thiamine-phosphate diphosphorylase activity
AMIS_63820	COG1643	Atp-dependent helicase
AMIS_63870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMIS_6390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIS_6390	COG2022	thiamine diphosphate biosynthetic process
AMIS_63930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMIS_64040	COG2202	Pas domain
AMIS_64040	COG2205	protein histidine kinase activity
AMIS_64050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMIS_64070	COG0405	Gamma-glutamyltransferase
AMIS_64090	COG2133	pyrroloquinoline quinone binding
AMIS_6410	COG2022	thiamine diphosphate biosynthetic process
AMIS_64120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMIS_64130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIS_64150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIS_6420	COG0352	thiamine-phosphate diphosphorylase activity
AMIS_64230	COG1686	Belongs to the peptidase S11 family
AMIS_64240	COG1191	sigma factor activity
AMIS_64260	COG3973	AAA domain
AMIS_64280	COG1191	sigma factor activity
AMIS_6430	COG0351	phosphomethylpyrimidine kinase
AMIS_64380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMIS_64390	COG1609	Transcriptional regulator
AMIS_6440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMIS_64410	COG4608	Belongs to the ABC transporter superfamily
AMIS_64420	COG0601	transmembrane transport
AMIS_64430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIS_64440	COG0444	Belongs to the ABC transporter superfamily
AMIS_64460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMIS_64480	COG0656	L-ascorbic acid biosynthetic process
AMIS_64500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMIS_64510	COG0187	DNA topoisomerase II activity
AMIS_64560	COG2205	protein histidine kinase activity
AMIS_64570	COG0745	RESPONSE REGULATOR receiver
AMIS_64580	COG0435	Glutathione S-transferase
AMIS_64610	COG0714	Associated with various cellular activities
AMIS_64630	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AMIS_64640	COG4106	trans-aconitate 2-methyltransferase activity
AMIS_64730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMIS_64800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMIS_64810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIS_64810	COG1017	nitric oxide dioxygenase activity
AMIS_64850	COG0395	ABC-type sugar transport system, permease component
AMIS_64920	COG0515	serine threonine protein kinase
AMIS_64940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMIS_64950	COG1136	(ABC) transporter
AMIS_64960	COG1136	(ABC) transporter
AMIS_650	COG1960	acyl-CoA dehydrogenase activity
AMIS_65000	COG3201	nicotinamide mononucleotide transporter
AMIS_65030	COG1874	Beta-galactosidase
AMIS_65030	COG0366	Alpha amylase catalytic
AMIS_65140	COG3629	intracellular signal transduction
AMIS_65150	COG0745	RESPONSE REGULATOR receiver
AMIS_65160	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AMIS_6520	COG2018	Roadblock/LC7 domain
AMIS_65210	COG4585	Histidine kinase
AMIS_65220	COG2197	response regulator
AMIS_65270	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AMIS_65280	COG3903	Transcriptional regulator
AMIS_65280	COG3629	intracellular signal transduction
AMIS_65360	COG0745	RESPONSE REGULATOR receiver
AMIS_65360	COG3706	GGDEF domain
AMIS_65370	COG0596	Alpha beta hydrolase
AMIS_65390	COG2318	DinB family
AMIS_65410	COG0671	phosphoesterase, PA-phosphatase related
AMIS_65430	COG1803	Methylglyoxal synthase
AMIS_65430	COG1597	lipid kinase activity
AMIS_65450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMIS_65500	COG0745	RESPONSE REGULATOR receiver
AMIS_65540	COG2197	response regulator
AMIS_65550	COG3850	Histidine kinase
AMIS_6560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMIS_65600	COG0546	phosphoglycolate phosphatase activity
AMIS_65620	COG1335	isochorismatase
AMIS_65640	COG0789	Transcriptional regulator
AMIS_65670	COG0800	Aldolase
AMIS_6570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMIS_65710	COG1063	alcohol dehydrogenase
AMIS_65740	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AMIS_65770	COG0438	transferase activity, transferring glycosyl groups
AMIS_65780	COG0438	transferase activity, transferring glycosyl groups
AMIS_6580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMIS_65810	COG2226	methyltransferase
AMIS_65820	COG0673	inositol 2-dehydrogenase activity
AMIS_65850	COG3483	tryptophan 2,3-dioxygenase activity
AMIS_65860	COG3012	SEC-C Motif Domain Protein
AMIS_65870	COG0840	transmembrane signaling receptor activity
AMIS_65890	COG1653	transport
AMIS_65900	COG1175	transmembrane transport
AMIS_65910	COG0395	ABC-type sugar transport system, permease component
AMIS_65920	COG0366	Alpha amylase catalytic
AMIS_65940	COG0659	secondary active sulfate transmembrane transporter activity
AMIS_65950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMIS_65960	COG2308	Evidence 4 Homologs of previously reported genes of
AMIS_65960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIS_65970	COG0367	asparagine synthase
AMIS_66040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMIS_6610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMIS_66100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIS_66170	COG2197	response regulator
AMIS_66220	COG1131	(ABC) transporter
AMIS_66230	COG0328	RNA-DNA hybrid ribonuclease activity
AMIS_66250	COG3285	dna ligase
AMIS_66250	COG1793	dna ligase
AMIS_66270	COG4585	Histidine kinase
AMIS_66280	COG2197	response regulator
AMIS_66290	COG5001	Diguanylate cyclase
AMIS_66330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMIS_66360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIS_6640	COG0736	holo-[acyl-carrier-protein] synthase activity
AMIS_66450	COG0438	transferase activity, transferring glycosyl groups
AMIS_66530	COG2807	transmembrane transport
AMIS_66570	COG0058	SHG alpha-glucan phosphorylase activity
AMIS_6660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMIS_66650	COG1960	acyl-CoA dehydrogenase activity
AMIS_66670	COG1309	transcriptional regulator
AMIS_66680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMIS_66770	COG2304	oxidoreductase activity
AMIS_66780	COG2304	oxidoreductase activity
AMIS_6680	COG0802	atpase or kinase
AMIS_66800	COG0714	Associated with various cellular activities
AMIS_66810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIS_66820	COG3693	PFAM glycoside hydrolase, family 10
AMIS_66840	COG0714	Associated with various cellular activities
AMIS_66850	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AMIS_66880	COG2409	Drug exporters of the RND superfamily
AMIS_6690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMIS_6700	COG0456	acetyltransferase
AMIS_6700	COG1214	PFAM Peptidase M22, glycoprotease
AMIS_67070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMIS_67090	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AMIS_67190	COG0483	inositol monophosphate 1-phosphatase activity
AMIS_6720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMIS_67230	COG4974	Belongs to the 'phage' integrase family
AMIS_67290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIS_67390	COG0633	Ferredoxin
AMIS_67390	COG0543	2 iron, 2 sulfur cluster binding
AMIS_6750	COG1132	(ABC) transporter
AMIS_67510	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AMIS_67550	COG0395	ABC-type sugar transport system, permease component
AMIS_67560	COG1175	transmembrane transport
AMIS_67570	COG1653	transport
AMIS_6760	COG0459	protein refolding
AMIS_67610	COG1960	acyl-CoA dehydrogenase activity
AMIS_67620	COG5001	Diguanylate cyclase
AMIS_67660	COG2197	response regulator
AMIS_67690	COG0028	Belongs to the TPP enzyme family
AMIS_6770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMIS_67750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMIS_6790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMIS_67920	COG0419	ATPase involved in DNA repair
AMIS_67930	COG0420	3'-5' exonuclease activity
AMIS_67990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMIS_68000	COG0156	8-amino-7-oxononanoate synthase activity
AMIS_68010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMIS_68040	COG2264	protein methyltransferase activity
AMIS_68130	COG1793	dna ligase
AMIS_68150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMIS_68170	COG3285	dna ligase
AMIS_68170	COG1793	dna ligase
AMIS_6820	COG4214	carbohydrate transport
AMIS_68200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMIS_68220	COG0463	Glycosyl transferase, family 2
AMIS_68240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMIS_68250	COG0655	NAD(P)H dehydrogenase (quinone) activity
AMIS_68260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMIS_68300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMIS_68320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIS_68330	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AMIS_68340	COG0183	Belongs to the thiolase family
AMIS_68350	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIS_68350	COG1024	Enoyl-CoA hydratase
AMIS_68370	COG2205	protein histidine kinase activity
AMIS_68380	COG0745	RESPONSE REGULATOR receiver
AMIS_68420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMIS_68430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMIS_68440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMIS_68450	COG0531	amino acid
AMIS_68460	COG0569	domain protein
AMIS_68510	COG0756	dUTP diphosphatase activity
AMIS_68600	COG2860	membrane
AMIS_68620	COG2313	pseudouridylate synthase activity
AMIS_6870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMIS_68710	COG2198	Histidine kinase
AMIS_68710	COG0643	Histidine kinase
AMIS_68720	COG0745	RESPONSE REGULATOR receiver
AMIS_68730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMIS_68750	COG2201	protein-glutamate methylesterase activity
AMIS_68760	COG0835	chemotaxis
AMIS_68770	COG3290	protein histidine kinase activity
AMIS_68770	COG0840	transmembrane signaling receptor activity
AMIS_68790	COG1490	D-aminoacyl-tRNA deacylase activity
AMIS_68840	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMIS_6890	COG2197	response regulator
AMIS_68920	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMIS_68930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMIS_68950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMIS_68970	COG0584	glycerophosphoryl diester phosphodiesterase
AMIS_68980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMIS_68990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMIS_69000	COG1196	nuclear chromosome segregation
AMIS_69030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMIS_69050	COG1126	abc transporter atp-binding protein
AMIS_69060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIS_69070	COG0765	amino acid transport
AMIS_69080	COG0765	amino acid transport
AMIS_69090	COG1418	mRNA catabolic process
AMIS_69100	COG2137	regulation of response to DNA damage stimulus
AMIS_69110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMIS_69120	COG1573	uracil-dna glycosylase
AMIS_69160	COG0515	serine threonine protein kinase
AMIS_69160	COG2815	serine threonine protein kinase
AMIS_69170	COG1201	RNA secondary structure unwinding
AMIS_6920	COG0516	GMP reductase activity
AMIS_69210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMIS_69240	COG1396	sequence-specific DNA binding
AMIS_69250	COG1058	Belongs to the CinA family
AMIS_69250	COG1546	Belongs to the CinA family
AMIS_69270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMIS_69320	COG1674	ftsk spoiiie
AMIS_69350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AMIS_69360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMIS_69380	COG3214	Protein conserved in bacteria
AMIS_6940	COG1316	TRANSCRIPTIONal
AMIS_69510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMIS_69530	COG0612	Peptidase, M16
AMIS_69540	COG1185	polyribonucleotide nucleotidyltransferase activity
AMIS_69550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMIS_69570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMIS_6960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMIS_6960	COG0519	Catalyzes the synthesis of GMP from XMP
AMIS_69600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AMIS_69610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMIS_69640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMIS_69650	COG0195	Participates in both transcription termination and antitermination
AMIS_69660	COG0779	Required for maturation of 30S ribosomal subunits
AMIS_6970	COG1051	belongs to the nudix hydrolase family
AMIS_69740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMIS_69750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMIS_69770	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_69810	COG4585	Histidine kinase
AMIS_69820	COG2197	response regulator
AMIS_69830	COG4152	abc transporter atp-binding protein
AMIS_69840	COG1668	transmembrane transport
AMIS_69850	COG1309	transcriptional regulator
AMIS_69860	COG1511	domain protein
AMIS_6990	COG1183	phosphatidylcholine synthase activity
AMIS_69950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMIS_69960	COG0750	zinc metalloprotease
AMIS_700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AMIS_7000	COG0688	phosphatidylethanolamine metabolic process
AMIS_70000	COG2146	nitrite reductase [NAD(P)H] activity
AMIS_70000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMIS_70030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMIS_70050	COG0233	cytoplasmic translational termination
AMIS_70060	COG0528	UMP kinase activity
AMIS_70070	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMIS_70080	COG0052	Belongs to the universal ribosomal protein uS2 family
AMIS_70100	COG0792	nuclease activity
AMIS_70110	COG0606	chelatase, subunit chli
AMIS_70150	COG4974	Belongs to the 'phage' integrase family
AMIS_70190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMIS_70210	COG0681	Belongs to the peptidase S26 family
AMIS_70220	COG0681	Belongs to the peptidase S26 family
AMIS_70230	COG0335	large ribosomal subunit rRNA binding
AMIS_70240	COG0336	Belongs to the RNA methyltransferase TrmD family
AMIS_70250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMIS_70260	COG1837	Belongs to the UPF0109 family
AMIS_70270	COG0228	four-way junction DNA binding
AMIS_70290	COG0442	prolyl-tRNA aminoacylation
AMIS_7030	COG4585	Histidine kinase
AMIS_70380	COG0438	transferase activity, transferring glycosyl groups
AMIS_70410	COG0463	Glycosyl transferase, family 2
AMIS_70450	COG1216	Glycosyl transferase, family 2
AMIS_70460	COG2755	lipolytic protein G-D-S-L family
AMIS_70460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMIS_70480	COG1216	Glycosyl transferase, family 2
AMIS_70480	COG1442	glycosyl transferase family 8
AMIS_70490	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMIS_70550	COG2318	DinB family
AMIS_70640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMIS_70660	COG0571	ribonuclease III activity
AMIS_70670	COG0416	fatty acid biosynthetic process
AMIS_70680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMIS_7070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIS_70710	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMIS_70720	COG0742	ribosomal rna small subunit methyltransferase
AMIS_70770	COG1461	Dihydroxyacetone kinase
AMIS_70780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMIS_7080	COG0444	Belongs to the ABC transporter superfamily
AMIS_70830	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMIS_70860	COG0626	cystathionine gamma-synthase activity
AMIS_70870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMIS_7090	COG4608	Belongs to the ABC transporter superfamily
AMIS_70910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMIS_70940	COG0776	regulation of translation
AMIS_70950	COG0066	3-isopropylmalate dehydratase activity
AMIS_710	COG1984	allophanate hydrolase subunit 2
AMIS_7100	COG1605	Chorismate mutase
AMIS_71000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMIS_71040	COG1476	TRANSCRIPTIONal
AMIS_71060	COG1131	(ABC) transporter
AMIS_71080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMIS_7110	COG0737	Belongs to the 5'-nucleotidase family
AMIS_7110	COG1525	nuclease
AMIS_7110	COG4085	toxin activity
AMIS_71120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIS_71130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIS_71160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMIS_71170	COG0473	3-isopropylmalate dehydrogenase activity
AMIS_71200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMIS_71210	COG0440	acetolactate synthase activity
AMIS_71230	COG3300	MHYT domain
AMIS_71230	COG5001	Diguanylate cyclase
AMIS_71240	COG0129	dihydroxy-acid dehydratase activity
AMIS_71270	COG1175	transmembrane transport
AMIS_71290	COG1609	Transcriptional regulator
AMIS_71320	COG2133	pyrroloquinoline quinone binding
AMIS_71350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMIS_71360	COG0154	amidase activity
AMIS_71370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMIS_71390	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMIS_71410	COG0482	sulfurtransferase activity
AMIS_71430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AMIS_71440	COG2086	electron transfer activity
AMIS_71450	COG2149	membrane
AMIS_71490	COG0443	Heat shock 70 kDa protein
AMIS_7150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMIS_71540	COG0840	transmembrane signaling receptor activity
AMIS_71550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIS_71560	COG1119	ATPase activity
AMIS_7160	COG0045	succinate-CoA ligase (ADP-forming) activity
AMIS_71600	COG2902	Dehydrogenase
AMIS_71620	COG0010	Belongs to the arginase family
AMIS_71630	COG3118	belongs to the thioredoxin family
AMIS_71680	COG0183	Belongs to the thiolase family
AMIS_71760	COG4133	protoheme IX ABC transporter activity
AMIS_71780	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AMIS_71810	COG1674	ftsk spoiiie
AMIS_71840	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIS_71880	COG0384	phenazine biosynthesis protein PhzF
AMIS_71900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMIS_71920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMIS_71930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMIS_71940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMIS_71950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMIS_71960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMIS_71970	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMIS_71980	COG0356	it plays a direct role in the translocation of protons across the membrane
AMIS_72010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMIS_72020	COG0702	epimerase
AMIS_72030	COG0009	L-threonylcarbamoyladenylate synthase
AMIS_72040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMIS_72060	COG2890	protein-(glutamine-N5) methyltransferase activity
AMIS_72070	COG3706	GGDEF domain
AMIS_7210	COG0138	bifunctional purine biosynthesis protein purh
AMIS_72100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMIS_72110	COG0254	rRNA binding
AMIS_72150	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AMIS_72170	COG0083	homoserine kinase activity
AMIS_72190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMIS_72230	COG0018	arginyl-trna synthetase
AMIS_72250	COG0460	homoserine dehydrogenase
AMIS_72260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMIS_72270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMIS_72290	COG3469	chitinase activity
AMIS_72370	COG1742	UPF0060 membrane protein
AMIS_7240	COG0538	isocitrate dehydrogenase activity
AMIS_72450	COG0754	glutathionylspermidine amidase activity
AMIS_72470	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_72480	COG0366	Alpha amylase catalytic
AMIS_7250	COG1454	alcohol dehydrogenase
AMIS_7250	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_72520	COG0586	Pfam SNARE associated Golgi protein
AMIS_72530	COG3469	chitinase activity
AMIS_72560	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIS_72590	COG0740	serine-type endopeptidase activity
AMIS_72610	COG1834	amidinotransferase
AMIS_72620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMIS_72680	COG3118	belongs to the thioredoxin family
AMIS_7270	COG1349	DNA-binding transcription factor activity
AMIS_72720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIS_72730	COG2205	protein histidine kinase activity
AMIS_72740	COG0745	RESPONSE REGULATOR receiver
AMIS_72780	COG0567	Dehydrogenase, E1 component
AMIS_72780	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIS_72800	COG0857	belongs to the CobB CobQ family
AMIS_72800	COG0280	phosphate acetyltransferase
AMIS_72810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMIS_72830	COG1064	alcohol dehydrogenase
AMIS_72870	COG2172	sigma factor antagonist activity
AMIS_72880	COG2188	Transcriptional regulator
AMIS_72900	COG1597	lipid kinase activity
AMIS_72930	COG0175	sulfate reduction
AMIS_72950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIS_72980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMIS_7300	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AMIS_73000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AMIS_73020	COG1595	DNA-templated transcription, initiation
AMIS_73050	COG2135	peptidase activity
AMIS_73060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMIS_73070	COG1162	GTPase activity
AMIS_73080	COG0483	inositol monophosphate 1-phosphatase activity
AMIS_73210	COG0861	Integral membrane protein TerC family
AMIS_73220	COG1357	PFAM Pentapeptide repeats (8 copies)
AMIS_73240	COG1615	UPF0182 protein
AMIS_73250	COG3480	Lon protease (S16) C-terminal proteolytic domain
AMIS_73310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMIS_73370	COG2816	NAD+ diphosphatase activity
AMIS_73400	COG1959	2 iron, 2 sulfur cluster binding
AMIS_73420	COG1116	anion transmembrane transporter activity
AMIS_73430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIS_73460	COG1278	Cold shock
AMIS_73490	COG1074	ATP-dependent DNA helicase activity
AMIS_73510	COG1611	Belongs to the LOG family
AMIS_73520	COG1611	Belongs to the LOG family
AMIS_73540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIS_73550	COG2171	N-acyltransferase activity
AMIS_73690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMIS_73700	COG1506	peptidase
AMIS_73700	COG0823	Involved in the tonB-independent uptake of proteins
AMIS_73720	COG0312	modulator of DNA gyrase
AMIS_73750	COG1053	succinate dehydrogenase
AMIS_73780	COG0411	ABC transporter
AMIS_73790	COG0410	ABC transporter
AMIS_73840	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_73860	COG1960	acyl-CoA dehydrogenase activity
AMIS_7390	COG0529	Catalyzes the synthesis of activated sulfate
AMIS_73910	COG2188	Transcriptional regulator
AMIS_73920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AMIS_73950	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_7410	COG1131	(ABC) transporter
AMIS_74150	COG0012	GTP binding
AMIS_74180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMIS_74180	COG2169	Transcriptional regulator
AMIS_74190	COG0525	valine-tRNA ligase activity
AMIS_74220	COG1322	Protein conserved in bacteria
AMIS_74230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMIS_74260	COG1570	exodeoxyribonuclease VII activity
AMIS_74270	COG1722	exodeoxyribonuclease VII activity
AMIS_74300	COG0705	Rhomboid family
AMIS_74330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMIS_74340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIS_74340	COG0561	phosphatase activity
AMIS_74350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMIS_74370	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AMIS_74440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMIS_74470	COG0515	serine threonine protein kinase
AMIS_74470	COG2815	serine threonine protein kinase
AMIS_74510	COG0424	maF-like protein
AMIS_74520	COG4770	biotin carboxylase activity
AMIS_7460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AMIS_74610	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIS_74610	COG1473	amidohydrolase
AMIS_74620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMIS_74620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMIS_74630	COG0515	serine threonine protein kinase
AMIS_74630	COG2815	serine threonine protein kinase
AMIS_74640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMIS_74660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AMIS_74670	COG1051	belongs to the nudix hydrolase family
AMIS_74680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMIS_74700	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_74710	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_74760	COG2018	Roadblock/LC7 domain
AMIS_74780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMIS_74860	COG1744	ABC transporter substrate-binding protein PnrA-like
AMIS_74910	COG0180	Tryptophanyl-tRNA synthetase
AMIS_74920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMIS_74930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AMIS_74980	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMIS_7500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMIS_75000	COG0193	aminoacyl-tRNA hydrolase activity
AMIS_75030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMIS_75070	COG0488	(ABC) transporter
AMIS_75080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMIS_75100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMIS_75120	COG0084	hydrolase, TatD family'
AMIS_75150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIS_75210	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMIS_75230	COG0726	polysaccharide deacetylase
AMIS_75300	COG0303	'Molybdopterin
AMIS_75310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMIS_75320	COG3706	GGDEF domain
AMIS_75320	COG0745	RESPONSE REGULATOR receiver
AMIS_75330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMIS_75410	COG2095	MarC family integral membrane protein
AMIS_75420	COG0613	PHP domain protein
AMIS_75470	COG3118	belongs to the thioredoxin family
AMIS_75530	COG0546	phosphoglycolate phosphatase activity
AMIS_75550	COG0384	phenazine biosynthesis protein PhzF
AMIS_75560	COG2239	Acts as a magnesium transporter
AMIS_75590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMIS_75600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIS_75610	COG4122	O-methyltransferase activity
AMIS_75620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMIS_75650	COG1024	Enoyl-CoA hydratase
AMIS_75670	COG0519	Catalyzes the synthesis of GMP from XMP
AMIS_7570	COG0148	phosphopyruvate hydratase activity
AMIS_75700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIS_75710	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMIS_75710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMIS_75720	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMIS_75730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMIS_75790	COG0113	porphobilinogen synthase activity
AMIS_75810	COG0181	hydroxymethylbilane synthase activity
AMIS_75820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMIS_75830	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AMIS_75860	COG0318	PFAM AMP-dependent synthetase and ligase
AMIS_75870	COG1595	DNA-templated transcription, initiation
AMIS_75930	COG0506	proline dehydrogenase activity
AMIS_75950	COG1082	Xylose isomerase domain protein TIM barrel
AMIS_760	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIS_7600	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMIS_76010	COG0588	phosphoglycerate mutase activity
AMIS_76040	COG0438	transferase activity, transferring glycosyl groups
AMIS_76070	COG0745	RESPONSE REGULATOR receiver
AMIS_76100	COG5002	protein histidine kinase activity
AMIS_76130	COG0739	heme binding
AMIS_76140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AMIS_76150	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AMIS_76170	COG4786	Flagellar basal body rod
AMIS_76170	COG1256	bacterial-type flagellum assembly
AMIS_76230	COG1815	bacterial-type flagellum-dependent cell motility
AMIS_76240	COG1558	bacterial-type flagellum-dependent cell motility
AMIS_76250	COG1677	Flagellar hook-basal body complex protein FliE
AMIS_76260	COG1766	The M ring may be actively involved in energy transduction
AMIS_76270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMIS_76290	COG1157	protein secretion by the type III secretion system
AMIS_76310	COG0739	heme binding
AMIS_76310	COG0741	lytic transglycosylase activity
AMIS_76310	COG1196	nuclear chromosome segregation
AMIS_76350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMIS_76360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMIS_76380	COG1338	Plays a role in the flagellum-specific transport system
AMIS_76400	COG1776	CheC inhibitor of MCP methylation
AMIS_76400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMIS_76440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMIS_76460	COG1749	Flagellar hook protein flgE
AMIS_76470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AMIS_76530	COG2201	protein-glutamate methylesterase activity
AMIS_76560	COG2198	Histidine kinase
AMIS_76560	COG0643	Histidine kinase
AMIS_76570	COG2198	Histidine kinase
AMIS_76570	COG0643	Histidine kinase
AMIS_76580	COG0745	RESPONSE REGULATOR receiver
AMIS_76590	COG2340	Cysteine-rich secretory protein family
AMIS_76600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMIS_76640	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AMIS_76710	COG3246	L-lysine catabolic process to acetate
AMIS_76730	COG0735	belongs to the Fur family
AMIS_76750	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AMIS_76780	COG1051	belongs to the nudix hydrolase family
AMIS_7680	COG0714	Associated with various cellular activities
AMIS_76810	COG1595	DNA-templated transcription, initiation
AMIS_76840	COG0306	phosphate transporter
AMIS_76880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMIS_76910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMIS_76920	COG0456	acetyltransferase
AMIS_76930	COG0745	RESPONSE REGULATOR receiver
AMIS_770	COG0022	dehydrogenase e1 component
AMIS_77000	COG2339	peptidase activity
AMIS_77010	COG4129	membrane
AMIS_77060	COG0459	protein refolding
AMIS_77090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMIS_77110	COG1131	(ABC) transporter
AMIS_77130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMIS_77160	COG1131	(ABC) transporter
AMIS_77170	COG1349	DNA-binding transcription factor activity
AMIS_77290	COG3842	ATPase activity
AMIS_77310	COG1278	Cold shock
AMIS_77330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMIS_77340	COG0215	cysteine-tRNA ligase activity
AMIS_77350	COG1404	Belongs to the peptidase S8 family
AMIS_77360	COG0114	fumarate hydratase activity
AMIS_77390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AMIS_77390	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AMIS_77430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMIS_7750	COG0183	Belongs to the thiolase family
AMIS_77510	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMIS_77520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMIS_77570	COG1960	acyl-CoA dehydrogenase activity
AMIS_77610	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMIS_77620	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AMIS_77660	COG3830	Belongs to the UPF0237 family
AMIS_77690	COG0542	response to heat
AMIS_77710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMIS_77720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMIS_77740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMIS_77760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMIS_77770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMIS_7780	COG3339	Conserved Protein
AMIS_77800	COG0649	NAD binding
AMIS_77870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMIS_77880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMIS_77940	COG0741	lytic transglycosylase activity
AMIS_77940	COG0739	heme binding
AMIS_77940	COG1196	nuclear chromosome segregation
AMIS_78000	COG1674	ftsk spoiiie
AMIS_78030	COG0302	gtp cyclohydrolase
AMIS_78040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMIS_78060	COG0037	tRNA processing
AMIS_78090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMIS_78110	COG1674	ftsk spoiiie
AMIS_78160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMIS_78230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIS_78280	COG0003	Pfam Anion-transporting ATPase
AMIS_78310	COG1610	YqeY-like protein
AMIS_78320	COG1408	metallophosphoesterase
AMIS_78340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMIS_78360	COG1324	tolerance protein
AMIS_7840	COG1234	tRNA 3'-trailer cleavage
AMIS_78400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIS_78450	COG4608	Belongs to the ABC transporter superfamily
AMIS_78460	COG0444	Belongs to the ABC transporter superfamily
AMIS_78480	COG0747	negative chemotaxis
AMIS_7850	COG2326	polyphosphate kinase activity
AMIS_78500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMIS_78590	COG0813	purine-nucleoside phosphorylase activity
AMIS_78600	COG0590	tRNA wobble adenosine to inosine editing
AMIS_78640	COG0287	Prephenate dehydrogenase
AMIS_78650	COG2318	DinB family
AMIS_78660	COG0235	Class ii aldolase
AMIS_78660	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AMIS_78670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AMIS_78670	COG1796	DNA polymerase
AMIS_78700	COG0642	Histidine kinase
AMIS_78710	COG2018	Roadblock/LC7 domain
AMIS_78840	COG3706	GGDEF domain
AMIS_7890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMIS_78930	COG0778	Nitroreductase
AMIS_78940	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMIS_79050	COG1268	BioY protein
AMIS_79070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIS_79130	COG0667	Aldo Keto reductase
AMIS_79160	COG0673	inositol 2-dehydrogenase activity
AMIS_79180	COG3831	ATPase activity
AMIS_79230	COG4558	Periplasmic binding protein
AMIS_79240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIS_79250	COG1120	ATPase activity
AMIS_79320	COG2132	Multicopper oxidase
AMIS_79420	COG1028	Short-chain dehydrogenase reductase Sdr
AMIS_79450	COG0745	RESPONSE REGULATOR receiver
AMIS_79460	COG2205	protein histidine kinase activity
AMIS_79490	COG1136	(ABC) transporter
AMIS_79490	COG0577	efflux transmembrane transporter activity
AMIS_79520	COG1131	(ABC) transporter
AMIS_79550	COG2197	response regulator
AMIS_79600	COG1131	(ABC) transporter
AMIS_79620	COG2197	response regulator
AMIS_79630	COG0596	Alpha beta hydrolase
AMIS_79650	COG3629	intracellular signal transduction
AMIS_79650	COG3903	Transcriptional regulator
AMIS_79690	COG4978	Transcriptional regulator
AMIS_79690	COG0789	Transcriptional regulator
AMIS_7970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMIS_79700	COG2197	response regulator
AMIS_79710	COG4585	Histidine kinase
AMIS_79760	COG4585	Histidine kinase
AMIS_79770	COG2197	response regulator
AMIS_79860	COG0583	DNA-binding transcription factor activity
AMIS_79920	COG1073	alpha beta
AMIS_79970	COG0242	peptide deformylase activity
AMIS_80	COG0187	DNA topoisomerase II activity
AMIS_80050	COG0789	Transcriptional regulator
AMIS_80060	COG3959	Transketolase, thiamine diphosphate binding domain
AMIS_80070	COG3958	Transketolase
AMIS_8010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMIS_80100	COG0457	Tetratricopeptide repeat
AMIS_80100	COG0705	Rhomboid family
AMIS_80110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMIS_80140	COG0598	Magnesium transport protein CorA
AMIS_80150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_80170	COG0371	Dehydrogenase
AMIS_8020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMIS_80210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMIS_80220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMIS_80230	COG3275	phosphorelay sensor kinase activity
AMIS_80250	COG0745	RESPONSE REGULATOR receiver
AMIS_80260	COG2205	protein histidine kinase activity
AMIS_80280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMIS_80350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMIS_8040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMIS_80420	COG2235	arginine
AMIS_80500	COG1764	response to oxidative stress
AMIS_80520	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMIS_80530	COG0561	phosphatase activity
AMIS_80540	COG0561	phosphatase activity
AMIS_80560	COG1834	amidinotransferase
AMIS_80570	COG1522	sequence-specific DNA binding
AMIS_80610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMIS_80620	COG3540	Alkaline phosphatase
AMIS_80630	COG3540	Alkaline phosphatase
AMIS_80670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMIS_80700	COG1408	metallophosphoesterase
AMIS_80720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMIS_80790	COG0315	cyclic pyranopterin monophosphate synthase activity
AMIS_80790	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMIS_80800	COG0315	cyclic pyranopterin monophosphate synthase activity
AMIS_80810	COG5001	Diguanylate cyclase
AMIS_80850	COG0305	Participates in initiation and elongation during chromosome replication
AMIS_80880	COG0359	binds to the 23S rRNA
AMIS_80890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMIS_80910	COG0360	Binds together with S18 to 16S ribosomal RNA
AMIS_80960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMIS_80980	COG1695	Transcriptional regulator
AMIS_8100	COG1331	Highly conserved protein containing a thioredoxin domain
AMIS_81010	COG1595	DNA-templated transcription, initiation
AMIS_81050	COG0617	tRNA 3'-terminal CCA addition
AMIS_81080	COG2815	serine threonine protein kinase
AMIS_81080	COG0515	serine threonine protein kinase
AMIS_81090	COG1595	DNA-templated transcription, initiation
AMIS_81130	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMIS_81130	COG3409	Peptidoglycan-binding domain 1 protein
AMIS_81150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIS_81160	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMIS_81190	COG1192	Involved in chromosome partitioning
AMIS_81200	COG0357	Ribosomal RNA small subunit methyltransferase G
AMIS_81220	COG0706	membrane insertase activity
AMIS_81230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMIS_81240	COG0594	ribonuclease P activity
AMIS_81250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMIS_8130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMIS_8160	COG1609	Transcriptional regulator
AMIS_8170	COG1414	Transcriptional regulator
AMIS_8190	COG2124	cytochrome p450
AMIS_8230	COG1609	Transcriptional regulator
AMIS_8260	COG0395	ABC-type sugar transport system, permease component
AMIS_8280	COG1609	Transcriptional regulator
AMIS_830	COG0443	Heat shock 70 kDa protein
AMIS_8390	COG1733	regulation of RNA biosynthetic process
AMIS_840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMIS_8410	COG1609	Transcriptional regulator
AMIS_8450	COG0477	Major facilitator Superfamily
AMIS_8480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMIS_850	COG0484	heat shock protein binding
AMIS_8500	COG0438	transferase activity, transferring glycosyl groups
AMIS_8530	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AMIS_8530	COG0778	Nitroreductase
AMIS_8560	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMIS_860	COG0789	Transcriptional regulator
AMIS_8600	COG0726	polysaccharide deacetylase
AMIS_8620	COG1012	belongs to the aldehyde dehydrogenase family
AMIS_8640	COG1515	deoxyribonuclease V activity
AMIS_8650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMIS_8660	COG2835	tetraacyldisaccharide 4'-kinase activity
AMIS_8690	COG1482	cell wall glycoprotein biosynthetic process
AMIS_8700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMIS_8730	COG0745	RESPONSE REGULATOR receiver
AMIS_8740	COG5002	protein histidine kinase activity
AMIS_8740	COG5000	phosphorelay sensor kinase activity
AMIS_8770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMIS_8780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIS_8790	COG0653	protein targeting
AMIS_8850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMIS_8860	COG2884	Cell division ATP-binding protein ftsE
AMIS_8870	COG2177	Part of the ABC transporter FtsEX involved in
AMIS_8880	COG0739	heme binding
AMIS_8880	COG1196	nuclear chromosome segregation
AMIS_8880	COG0741	lytic transglycosylase activity
AMIS_8890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMIS_8960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMIS_8970	COG1678	Uncharacterized ACR, COG1678
AMIS_90	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMIS_900	COG2814	Major facilitator Superfamily
AMIS_9020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMIS_9040	COG1459	type II secretion system
AMIS_9060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMIS_9090	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIS_910	COG0542	response to heat
AMIS_9250	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AMIS_9260	COG5001	Diguanylate cyclase
AMIS_9260	COG5002	protein histidine kinase activity
AMIS_9300	COG1793	dna ligase
AMIS_9300	COG3285	dna ligase
AMIS_9320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIS_9330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMIS_9370	COG1335	isochorismatase
AMIS_9380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMIS_9450	COG1234	tRNA 3'-trailer cleavage
AMIS_9460	COG0438	transferase activity, transferring glycosyl groups
AMIS_9470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMIS_9480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMIS_9510	COG1228	amidohydrolase
AMIS_9540	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMIS_9570	COG3217	Mosc domain protein beta barrel domain protein
AMIS_9570	COG0633	Ferredoxin
AMIS_960	COG0640	Transcriptional regulator
AMIS_9710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMIS_9720	COG5297	Belongs to the glycosyl hydrolase family 6
AMIS_9760	COG3226	Transcriptional regulator
AMIS_980	COG0586	Pfam SNARE associated Golgi protein
AMIS_9810	COG0653	protein targeting
AMIS_9830	COG0431	NADPH-dependent FMN reductase
AMIS_9840	COG3119	arylsulfatase activity
AMIS_9850	COG2124	cytochrome p450
AMIS_990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMIS_9980	COG1472	Belongs to the glycosyl hydrolase 3 family