locus-tag	class	description
Asp14428_00050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_00070	COG1672	PFAM Archaeal ATPase
Asp14428_00070	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asp14428_00130	COG2814	Major facilitator Superfamily
Asp14428_00150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asp14428_00160	COG1132	(ABC) transporter
Asp14428_00190	COG3250	beta-galactosidase activity
Asp14428_00210	COG1408	metallophosphoesterase
Asp14428_00230	COG1072	(Pantothenic acid kinase))
Asp14428_00270	COG4124	Belongs to the glycosyl hydrolase 26 family
Asp14428_00270	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Asp14428_00280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Asp14428_00320	COG1216	Glycosyl transferase, family 2
Asp14428_00410	COG0515	serine threonine protein kinase
Asp14428_00430	COG0531	amino acid
Asp14428_00460	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asp14428_00480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Asp14428_00630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Asp14428_00650	COG5001	Diguanylate cyclase
Asp14428_00660	COG1063	alcohol dehydrogenase
Asp14428_00670	COG0166	Belongs to the GPI family
Asp14428_00760	COG0406	alpha-ribazole phosphatase activity
Asp14428_00770	COG1620	l-lactate permease
Asp14428_00780	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asp14428_00790	COG2890	protein-(glutamine-N5) methyltransferase activity
Asp14428_00810	COG1609	Transcriptional regulator
Asp14428_00820	COG0789	Transcriptional regulator
Asp14428_00850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asp14428_00900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Asp14428_00930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Asp14428_00940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_01030	COG4134	Bacterial extracellular solute-binding protein
Asp14428_01070	COG4948	Mandelate Racemase Muconate Lactonizing
Asp14428_01090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asp14428_01100	COG0438	transferase activity, transferring glycosyl groups
Asp14428_01140	COG0740	serine-type endopeptidase activity
Asp14428_01150	COG0740	serine-type endopeptidase activity
Asp14428_01230	COG3509	depolymerase
Asp14428_01240	COG4213	ABC transporter substrate-binding protein
Asp14428_01290	COG2205	protein histidine kinase activity
Asp14428_01300	COG0745	RESPONSE REGULATOR receiver
Asp14428_01350	COG5001	Diguanylate cyclase
Asp14428_01370	COG3119	arylsulfatase activity
Asp14428_01470	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Asp14428_01480	COG3104	oligopeptide transport
Asp14428_01500	COG0745	RESPONSE REGULATOR receiver
Asp14428_01590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asp14428_01590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asp14428_01610	COG1122	ATPase activity
Asp14428_01620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Asp14428_01640	COG0310	cobalt ion transport
Asp14428_01750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Asp14428_01770	COG0247	lactate metabolic process
Asp14428_01780	COG0277	FAD linked oxidase domain protein
Asp14428_01790	COG0277	FAD linked oxidase domain protein
Asp14428_01890	COG0435	Glutathione S-transferase
Asp14428_01940	COG0514	ATP-dependent DNA helicase (RecQ)
Asp14428_01950	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asp14428_01970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asp14428_01980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asp14428_01980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asp14428_02010	COG0438	transferase activity, transferring glycosyl groups
Asp14428_02090	COG0326	Molecular chaperone. Has ATPase activity
Asp14428_02100	COG2130	NADP-dependent
Asp14428_02110	COG0537	adenosine 5'-monophosphoramidase activity
Asp14428_02120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Asp14428_02150	COG0477	Major facilitator Superfamily
Asp14428_02160	COG1309	transcriptional regulator
Asp14428_02180	COG4221	oxidoreductase activity
Asp14428_02210	COG0778	Nitroreductase
Asp14428_02220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asp14428_02230	COG1472	Belongs to the glycosyl hydrolase 3 family
Asp14428_02260	COG4565	transcriptional regulatory protein
Asp14428_02270	COG3290	protein histidine kinase activity
Asp14428_02280	COG1301	dicarboxylic acid transport
Asp14428_02300	COG1175	transmembrane transport
Asp14428_02320	COG1609	Transcriptional regulator
Asp14428_02390	COG1609	Transcriptional regulator
Asp14428_02430	COG0477	Major facilitator Superfamily
Asp14428_02470	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_02510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Asp14428_02520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asp14428_02540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asp14428_02550	COG1177	transmembrane transport
Asp14428_02560	COG1176	ABC-type spermidine putrescine transport system, permease component I
Asp14428_02580	COG3842	ATPase activity
Asp14428_02590	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_02620	COG1404	Belongs to the peptidase S8 family
Asp14428_02690	COG2936	dipeptidyl-peptidase activity
Asp14428_02710	COG1177	transmembrane transport
Asp14428_02740	COG0667	Aldo Keto reductase
Asp14428_02760	COG1404	Belongs to the peptidase S8 family
Asp14428_02790	COG0431	NADPH-dependent FMN reductase
Asp14428_02810	COG0318	PFAM AMP-dependent synthetase and ligase
Asp14428_02840	COG4251	negative regulation of phosphorylation
Asp14428_02850	COG0784	Response regulator, receiver
Asp14428_02920	COG3629	intracellular signal transduction
Asp14428_02920	COG3903	Transcriptional regulator
Asp14428_02990	COG0243	molybdopterin cofactor binding
Asp14428_03000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Asp14428_03010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Asp14428_03020	COG2146	nitrite reductase [NAD(P)H] activity
Asp14428_03030	COG2223	nitrite transmembrane transporter activity
Asp14428_03170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asp14428_03190	COG1733	regulation of RNA biosynthetic process
Asp14428_03310	COG0583	DNA-binding transcription factor activity
Asp14428_03410	COG4948	Mandelate Racemase Muconate Lactonizing
Asp14428_03440	COG1652	LysM domain
Asp14428_03450	COG1609	Transcriptional regulator
Asp14428_03460	COG4209	transmembrane transport
Asp14428_03510	COG5297	Belongs to the glycosyl hydrolase family 6
Asp14428_03510	COG4733	cellulase activity
Asp14428_03550	COG1879	ABC-type sugar transport system periplasmic component
Asp14428_03560	COG1879	ABC-type sugar transport system periplasmic component
Asp14428_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_03590	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_03610	COG2815	serine threonine protein kinase
Asp14428_03610	COG0515	serine threonine protein kinase
Asp14428_03700	COG3384	dioxygenase
Asp14428_03750	COG2188	Transcriptional regulator
Asp14428_03780	COG3718	enzyme involved in inositol metabolism
Asp14428_03790	COG3962	Belongs to the TPP enzyme family
Asp14428_03840	COG0673	inositol 2-dehydrogenase activity
Asp14428_03860	COG1309	transcriptional regulator
Asp14428_03870	COG2050	protein possibly involved in aromatic compounds catabolism
Asp14428_03890	COG0183	Belongs to the thiolase family
Asp14428_03900	COG1024	Enoyl-CoA hydratase
Asp14428_03920	COG3396	Phenylacetate-CoA oxygenase
Asp14428_03930	COG3460	Phenylacetate-CoA oxygenase
Asp14428_03940	COG3396	Phenylacetate-CoA oxygenase
Asp14428_03950	COG2151	metal-sulfur cluster biosynthetic enzyme
Asp14428_03960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asp14428_03980	COG4106	trans-aconitate 2-methyltransferase activity
Asp14428_04000	COG2409	Drug exporters of the RND superfamily
Asp14428_04010	COG1846	Transcriptional regulator
Asp14428_04050	COG0589	response to stress
Asp14428_04100	COG0318	PFAM AMP-dependent synthetase and ligase
Asp14428_04100	COG0204	Acyl-transferase
Asp14428_04250	COG3022	response to hydroperoxide
Asp14428_04260	COG3022	response to hydroperoxide
Asp14428_04300	COG2197	response regulator
Asp14428_04320	COG3300	MHYT domain
Asp14428_04320	COG5001	Diguanylate cyclase
Asp14428_04330	COG4251	negative regulation of phosphorylation
Asp14428_04330	COG5001	Diguanylate cyclase
Asp14428_04330	COG2203	Gaf domain
Asp14428_04330	COG3706	GGDEF domain
Asp14428_04340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Asp14428_04420	COG0437	4 iron, 4 sulfur cluster binding
Asp14428_04460	COG0709	Synthesizes selenophosphate from selenide and ATP
Asp14428_04500	COG1921	L-seryl-tRNASec selenium transferase activity
Asp14428_04720	COG0701	Predicted permease
Asp14428_04730	COG0701	Predicted permease
Asp14428_04830	COG2080	2 iron, 2 sulfur cluster binding
Asp14428_04830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Asp14428_04850	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Asp14428_04960	COG2770	Histidine kinase
Asp14428_04960	COG2208	phosphoserine phosphatase activity
Asp14428_04970	COG0515	serine threonine protein kinase
Asp14428_04970	COG2815	serine threonine protein kinase
Asp14428_05000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Asp14428_05060	COG0142	geranyltranstransferase activity
Asp14428_05090	COG3201	nicotinamide mononucleotide transporter
Asp14428_05100	COG0515	serine threonine protein kinase
Asp14428_05110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asp14428_05150	COG0747	negative chemotaxis
Asp14428_05170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asp14428_05180	COG0444	Belongs to the ABC transporter superfamily
Asp14428_05190	COG4608	Belongs to the ABC transporter superfamily
Asp14428_05200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_05210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_05220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_05230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_05400	COG0589	response to stress
Asp14428_05430	COG1960	acyl-CoA dehydrogenase activity
Asp14428_05460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Asp14428_05470	COG0531	amino acid
Asp14428_05500	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Asp14428_05540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asp14428_05580	COG1744	ABC transporter substrate-binding protein PnrA-like
Asp14428_05590	COG2318	DinB family
Asp14428_05610	COG0515	serine threonine protein kinase
Asp14428_05610	COG2815	serine threonine protein kinase
Asp14428_05720	COG2205	protein histidine kinase activity
Asp14428_05720	COG2202	Pas domain
Asp14428_05740	COG0577	efflux transmembrane transporter activity
Asp14428_05740	COG1136	(ABC) transporter
Asp14428_05750	COG0577	efflux transmembrane transporter activity
Asp14428_05750	COG1136	(ABC) transporter
Asp14428_05780	COG0745	RESPONSE REGULATOR receiver
Asp14428_05790	COG2205	protein histidine kinase activity
Asp14428_05800	COG0642	Histidine kinase
Asp14428_05820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asp14428_05820	COG0574	Belongs to the PEP-utilizing enzyme family
Asp14428_05830	COG0574	Belongs to the PEP-utilizing enzyme family
Asp14428_05830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asp14428_05860	COG0589	response to stress
Asp14428_05870	COG0058	SHG alpha-glucan phosphorylase activity
Asp14428_05890	COG0395	ABC-type sugar transport system, permease component
Asp14428_05900	COG1175	transmembrane transport
Asp14428_05910	COG1653	transport
Asp14428_05920	COG0516	GMP reductase activity
Asp14428_05920	COG0517	IMP dehydrogenase activity
Asp14428_05970	COG1621	beta-fructofuranosidase activity
Asp14428_06010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Asp14428_06020	COG1271	oxidase subunit
Asp14428_06030	COG1294	oxidase, subunit
Asp14428_06040	COG4988	ABC transporter
Asp14428_06050	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Asp14428_06140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asp14428_06150	COG1960	acyl-CoA dehydrogenase activity
Asp14428_06200	COG3237	CsbD-like
Asp14428_06210	COG1509	lysine 2,3-aminomutase activity
Asp14428_06220	COG0604	alcohol dehydrogenase
Asp14428_06230	COG1228	amidohydrolase
Asp14428_06240	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Asp14428_06250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asp14428_06260	COG1607	acyl-coa hydrolase
Asp14428_06290	COG0463	Glycosyl transferase, family 2
Asp14428_06380	COG1404	Belongs to the peptidase S8 family
Asp14428_06430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asp14428_06440	COG4257	antibiotic catabolic process
Asp14428_06500	COG0640	Transcriptional regulator
Asp14428_06510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asp14428_06530	COG1063	alcohol dehydrogenase
Asp14428_06550	COG1175	transmembrane transport
Asp14428_06610	COG4702	Belongs to the UPF0303 family
Asp14428_06650	COG1846	Transcriptional regulator
Asp14428_06660	COG1764	response to oxidative stress
Asp14428_06670	COG2267	carboxylic ester hydrolase activity
Asp14428_06780	COG2197	response regulator
Asp14428_06870	COG1968	undecaprenyl-diphosphatase activity
Asp14428_06880	COG4974	Belongs to the 'phage' integrase family
Asp14428_06890	COG0488	(ABC) transporter
Asp14428_06900	COG1191	sigma factor activity
Asp14428_06910	COG2197	response regulator
Asp14428_06920	COG4585	Histidine kinase
Asp14428_06950	COG1131	(ABC) transporter
Asp14428_06990	COG0019	diaminopimelate decarboxylase activity
Asp14428_07000	COG0494	nUDIX hydrolase
Asp14428_07030	COG2318	DinB family
Asp14428_07040	COG0702	epimerase
Asp14428_07070	COG0242	peptide deformylase activity
Asp14428_07100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Asp14428_07100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Asp14428_07110	COG0667	Aldo Keto reductase
Asp14428_07210	COG2205	protein histidine kinase activity
Asp14428_07220	COG0745	RESPONSE REGULATOR receiver
Asp14428_07370	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Asp14428_07380	COG0384	phenazine biosynthesis protein PhzF
Asp14428_07390	COG0488	(ABC) transporter
Asp14428_07400	COG1649	PFAM Uncharacterised BCR, COG1649
Asp14428_07430	COG0297	glycogen (starch) synthase activity
Asp14428_07440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Asp14428_07650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asp14428_07680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asp14428_07680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asp14428_07690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_07700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Asp14428_07710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_07720	COG1116	anion transmembrane transporter activity
Asp14428_07750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asp14428_07770	COG2207	Transcriptional regulator
Asp14428_07850	COG0309	Hydrogenase expression formation protein (HypE)
Asp14428_07870	COG0298	carbon dioxide binding
Asp14428_07950	COG1830	Aldolase
Asp14428_07960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asp14428_07990	COG0300	oxidoreductase activity
Asp14428_08000	COG2205	protein histidine kinase activity
Asp14428_08010	COG0745	RESPONSE REGULATOR receiver
Asp14428_08030	COG1752	Esterase of the alpha-beta hydrolase superfamily
Asp14428_08080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_08090	COG4948	Mandelate Racemase Muconate Lactonizing
Asp14428_08140	COG1228	amidohydrolase
Asp14428_08150	COG1733	regulation of RNA biosynthetic process
Asp14428_08240	COG0589	response to stress
Asp14428_08260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Asp14428_08320	COG1131	(ABC) transporter
Asp14428_08330	COG3559	Exporter of polyketide antibiotics
Asp14428_08390	COG3559	Exporter of polyketide antibiotics
Asp14428_08400	COG1131	(ABC) transporter
Asp14428_08440	COG0493	'glutamate synthase
Asp14428_08450	COG1013	pyruvate-flavodoxin oxidoreductase activity
Asp14428_08450	COG0674	pyruvate-flavodoxin oxidoreductase activity
Asp14428_08450	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Asp14428_08450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Asp14428_08530	COG1882	Formate acetyltransferase
Asp14428_08540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Asp14428_08600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asp14428_08630	COG1309	transcriptional regulator
Asp14428_08640	COG2239	Acts as a magnesium transporter
Asp14428_08730	COG2197	response regulator
Asp14428_08770	COG1136	(ABC) transporter
Asp14428_08770	COG0577	efflux transmembrane transporter activity
Asp14428_08810	COG0492	ferredoxin-NADP+ reductase activity
Asp14428_08820	COG2207	Transcriptional regulator
Asp14428_08830	COG0667	Aldo Keto reductase
Asp14428_08870	COG0531	amino acid
Asp14428_08920	COG0148	phosphopyruvate hydratase activity
Asp14428_08930	COG0446	pyridine nucleotide-disulphide oxidoreductase
Asp14428_08940	COG2072	flavoprotein involved in K transport
Asp14428_08960	COG1309	transcriptional regulator
Asp14428_09000	COG3268	Saccharopine dehydrogenase
Asp14428_09010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Asp14428_09030	COG1960	acyl-CoA dehydrogenase activity
Asp14428_09040	COG3903	Transcriptional regulator
Asp14428_09040	COG3629	intracellular signal transduction
Asp14428_09050	COG0596	Alpha beta hydrolase
Asp14428_09060	COG1309	transcriptional regulator
Asp14428_09070	COG0477	Major facilitator Superfamily
Asp14428_09080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asp14428_09110	COG0024	Methionine aminopeptidase
Asp14428_09150	COG1105	Belongs to the carbohydrate kinase PfkB family
Asp14428_09180	COG0395	ABC-type sugar transport system, permease component
Asp14428_09190	COG1175	transmembrane transport
Asp14428_09200	COG2182	Extracellular solute-binding protein
Asp14428_09210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asp14428_09230	COG1349	DNA-binding transcription factor activity
Asp14428_09240	COG0442	prolyl-tRNA aminoacylation
Asp14428_09380	COG0745	RESPONSE REGULATOR receiver
Asp14428_09420	COG2188	Transcriptional regulator
Asp14428_09440	COG0133	tryptophan synthase activity
Asp14428_09460	COG2226	methyltransferase
Asp14428_09500	COG0501	Belongs to the peptidase M48B family
Asp14428_09520	COG1271	oxidase subunit
Asp14428_09530	COG1294	oxidase, subunit
Asp14428_09540	COG4988	ABC transporter
Asp14428_09600	COG0859	PFAM glycosyl transferase family 9
Asp14428_09610	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_09620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Asp14428_09620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Asp14428_09630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Asp14428_09640	COG0297	glycogen (starch) synthase activity
Asp14428_09660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Asp14428_09680	COG2192	nodulation
Asp14428_09710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_09790	COG2801	Transposase and inactivated derivatives
Asp14428_09920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asp14428_09930	COG1132	(ABC) transporter
Asp14428_09940	COG1132	(ABC) transporter
Asp14428_09960	COG1309	transcriptional regulator
Asp14428_10030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asp14428_10030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asp14428_10120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_10150	COG2205	protein histidine kinase activity
Asp14428_10160	COG0745	RESPONSE REGULATOR receiver
Asp14428_10190	COG0577	efflux transmembrane transporter activity
Asp14428_10190	COG1136	(ABC) transporter
Asp14428_10200	COG0577	efflux transmembrane transporter activity
Asp14428_10200	COG1136	(ABC) transporter
Asp14428_10220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_10260	COG4566	intracellular signal transduction
Asp14428_10290	COG2204	response regulator
Asp14428_10300	COG0745	RESPONSE REGULATOR receiver
Asp14428_10310	COG1404	Belongs to the peptidase S8 family
Asp14428_10320	COG5002	protein histidine kinase activity
Asp14428_10350	COG0659	secondary active sulfate transmembrane transporter activity
Asp14428_10380	COG2200	EAL domain
Asp14428_10380	COG3287	FIST C domain
Asp14428_10380	COG2199	diguanylate cyclase activity
Asp14428_10390	COG0745	RESPONSE REGULATOR receiver
Asp14428_10460	COG0438	transferase activity, transferring glycosyl groups
Asp14428_10470	COG1216	Glycosyl transferase, family 2
Asp14428_10610	COG0243	molybdopterin cofactor binding
Asp14428_10620	COG0028	Belongs to the TPP enzyme family
Asp14428_10690	COG5002	protein histidine kinase activity
Asp14428_10740	COG0248	Ppx GppA phosphatase
Asp14428_10750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Asp14428_10760	COG1940	carbohydrate kinase activity
Asp14428_10770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asp14428_10800	COG4221	oxidoreductase activity
Asp14428_10830	COG1140	nitrate reductase beta subunit
Asp14428_10890	COG1846	Transcriptional regulator
Asp14428_10900	COG0745	RESPONSE REGULATOR receiver
Asp14428_10910	COG4251	negative regulation of phosphorylation
Asp14428_10940	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_10950	COG0477	Major facilitator Superfamily
Asp14428_10990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asp14428_11000	COG0300	oxidoreductase activity
Asp14428_11030	COG1595	DNA-templated transcription, initiation
Asp14428_11050	COG0463	Glycosyl transferase, family 2
Asp14428_11070	COG0477	Major facilitator Superfamily
Asp14428_11120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asp14428_11130	COG0745	RESPONSE REGULATOR receiver
Asp14428_11140	COG2205	protein histidine kinase activity
Asp14428_11170	COG5001	Diguanylate cyclase
Asp14428_11180	COG3250	beta-galactosidase activity
Asp14428_11190	COG1070	Carbohydrate kinase
Asp14428_11200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Asp14428_11240	COG3181	Tripartite tricarboxylate transporter family receptor
Asp14428_11270	COG1733	regulation of RNA biosynthetic process
Asp14428_11300	COG0574	Belongs to the PEP-utilizing enzyme family
Asp14428_11300	COG3848	Pyruvate phosphate dikinase
Asp14428_11310	COG4565	transcriptional regulatory protein
Asp14428_11320	COG3290	protein histidine kinase activity
Asp14428_11410	COG1960	acyl-CoA dehydrogenase activity
Asp14428_11460	COG1309	transcriptional regulator
Asp14428_11470	COG2409	Drug exporters of the RND superfamily
Asp14428_11510	COG1309	transcriptional regulator
Asp14428_11520	COG4221	oxidoreductase activity
Asp14428_11540	COG3971	2-oxopent-4-enoate hydratase activity
Asp14428_11550	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Asp14428_11560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asp14428_11570	COG3384	dioxygenase
Asp14428_11610	COG1414	Transcriptional regulator
Asp14428_11690	COG0439	Biotin carboxylase
Asp14428_11730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Asp14428_11830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Asp14428_11980	COG0438	transferase activity, transferring glycosyl groups
Asp14428_12050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Asp14428_12060	COG0673	inositol 2-dehydrogenase activity
Asp14428_12110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Asp14428_12140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Asp14428_12160	COG3250	beta-galactosidase activity
Asp14428_12200	COG3903	Transcriptional regulator
Asp14428_12200	COG3629	intracellular signal transduction
Asp14428_12230	COG0515	serine threonine protein kinase
Asp14428_12250	COG4106	trans-aconitate 2-methyltransferase activity
Asp14428_12270	COG1132	(ABC) transporter
Asp14428_12290	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_12300	COG4941	Belongs to the sigma-70 factor family
Asp14428_12310	COG3795	YCII-related domain
Asp14428_12330	COG0667	Aldo Keto reductase
Asp14428_12340	COG1876	peptidase activity
Asp14428_12380	COG1674	ftsk spoiiie
Asp14428_12390	COG1404	Belongs to the peptidase S8 family
Asp14428_12410	COG0589	response to stress
Asp14428_12460	COG1320	monovalent cation:proton antiporter activity
Asp14428_12470	COG2212	antiporter activity
Asp14428_12490	COG0651	ATP synthesis coupled electron transport
Asp14428_12510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Asp14428_12510	COG2111	Na H antiporter
Asp14428_12520	COG0490	domain, Protein
Asp14428_12550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Asp14428_12550	COG0617	tRNA 3'-terminal CCA addition
Asp14428_12550	COG0517	IMP dehydrogenase activity
Asp14428_12660	COG4176	ABC-type proline glycine betaine transport system permease component
Asp14428_12670	COG0517	IMP dehydrogenase activity
Asp14428_12670	COG4175	Glycine betaine
Asp14428_12680	COG4175	Glycine betaine
Asp14428_12700	COG1414	Transcriptional regulator
Asp14428_12710	COG5002	protein histidine kinase activity
Asp14428_12720	COG0745	RESPONSE REGULATOR receiver
Asp14428_12730	COG0475	glutathione-regulated potassium exporter activity
Asp14428_12760	COG1304	FMN binding
Asp14428_12780	COG2986	histidine ammonia-lyase
Asp14428_12810	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Asp14428_12820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Asp14428_12880	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_12890	COG1846	Transcriptional regulator
Asp14428_12950	COG4585	Histidine kinase
Asp14428_13000	COG1674	ftsk spoiiie
Asp14428_13100	COG1476	TRANSCRIPTIONal
Asp14428_13130	COG5001	Diguanylate cyclase
Asp14428_13140	COG1309	transcriptional regulator
Asp14428_13260	COG2208	phosphoserine phosphatase activity
Asp14428_13270	COG0745	RESPONSE REGULATOR receiver
Asp14428_13280	COG2205	protein histidine kinase activity
Asp14428_13310	COG1136	(ABC) transporter
Asp14428_13320	COG1136	(ABC) transporter
Asp14428_13320	COG0577	efflux transmembrane transporter activity
Asp14428_13330	COG0473	3-isopropylmalate dehydrogenase activity
Asp14428_13340	COG1802	Transcriptional regulator
Asp14428_13370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asp14428_13410	COG2205	protein histidine kinase activity
Asp14428_13420	COG5002	protein histidine kinase activity
Asp14428_13420	COG3850	Histidine kinase
Asp14428_13430	COG0745	RESPONSE REGULATOR receiver
Asp14428_13440	COG1840	ABC-type Fe3 transport system, periplasmic component
Asp14428_13450	COG1178	ABC-type Fe3 transport system permease component
Asp14428_13460	COG3842	ATPase activity
Asp14428_13520	COG2409	Drug exporters of the RND superfamily
Asp14428_13530	COG0745	RESPONSE REGULATOR receiver
Asp14428_13540	COG2205	protein histidine kinase activity
Asp14428_13560	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Asp14428_13600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asp14428_13620	COG0215	cysteine-tRNA ligase activity
Asp14428_13630	COG0366	Alpha amylase catalytic
Asp14428_13640	COG0640	Transcriptional regulator
Asp14428_13690	COG0402	S-adenosylhomocysteine deaminase activity
Asp14428_13770	COG0667	Aldo Keto reductase
Asp14428_13860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asp14428_13880	COG3629	intracellular signal transduction
Asp14428_13880	COG3903	Transcriptional regulator
Asp14428_13890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_13890	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Asp14428_13980	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Asp14428_14000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_14080	COG3631	Ketosteroid isomerase-related protein
Asp14428_14090	COG0702	epimerase
Asp14428_14100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asp14428_14120	COG1136	(ABC) transporter
Asp14428_14160	COG2249	NAD(P)H dehydrogenase (quinone) activity
Asp14428_14240	COG2080	2 iron, 2 sulfur cluster binding
Asp14428_14250	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Asp14428_14260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Asp14428_14270	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Asp14428_14290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asp14428_14300	COG0028	Belongs to the TPP enzyme family
Asp14428_14350	COG2197	response regulator
Asp14428_14360	COG4585	Histidine kinase
Asp14428_14440	COG0667	Aldo Keto reductase
Asp14428_14620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Asp14428_14630	COG1940	carbohydrate kinase activity
Asp14428_14640	COG4214	carbohydrate transport
Asp14428_14660	COG4213	ABC transporter substrate-binding protein
Asp14428_14790	COG2274	protein secretion by the type I secretion system
Asp14428_14800	COG1122	ATPase activity
Asp14428_14880	COG2234	aminopeptidase activity
Asp14428_14900	COG3629	intracellular signal transduction
Asp14428_14900	COG3903	Transcriptional regulator
Asp14428_14910	COG3903	Transcriptional regulator
Asp14428_14910	COG3629	intracellular signal transduction
Asp14428_14940	COG2124	cytochrome p450
Asp14428_14950	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Asp14428_14980	COG1404	Belongs to the peptidase S8 family
Asp14428_15080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asp14428_15090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Asp14428_15100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asp14428_15110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Asp14428_15180	COG0626	cystathionine gamma-synthase activity
Asp14428_15200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_15210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asp14428_15230	COG2124	cytochrome p450
Asp14428_15240	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_15270	COG0765	amino acid transport
Asp14428_15310	COG1113	amino acid transport
Asp14428_15360	COG2205	protein histidine kinase activity
Asp14428_15370	COG0745	RESPONSE REGULATOR receiver
Asp14428_15390	COG2205	protein histidine kinase activity
Asp14428_15400	COG0745	RESPONSE REGULATOR receiver
Asp14428_15430	COG1131	(ABC) transporter
Asp14428_15440	COG1725	Transcriptional regulator
Asp14428_15470	COG3842	ATPase activity
Asp14428_15480	COG1725	Transcriptional regulator
Asp14428_15530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asp14428_15570	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asp14428_15580	COG0022	dehydrogenase e1 component
Asp14428_15610	COG4585	Histidine kinase
Asp14428_15620	COG2197	response regulator
Asp14428_15630	COG1136	(ABC) transporter
Asp14428_15630	COG4591	ABC-type transport system involved in lipoprotein release permease component
Asp14428_15690	COG2813	Specifically methylates the guanine in position
Asp14428_15700	COG2318	DinB family
Asp14428_15740	COG0840	transmembrane signaling receptor activity
Asp14428_15750	COG1132	(ABC) transporter
Asp14428_15780	COG2175	clavaminate synthase activity
Asp14428_15860	COG0583	DNA-binding transcription factor activity
Asp14428_15880	COG1316	TRANSCRIPTIONal
Asp14428_15960	COG2267	carboxylic ester hydrolase activity
Asp14428_16020	COG3304	Inner membrane component domain
Asp14428_16040	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_16080	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Asp14428_16090	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Asp14428_16110	COG3336	cytochrome c oxidase
Asp14428_16130	COG3250	beta-galactosidase activity
Asp14428_16150	COG0596	Alpha beta hydrolase
Asp14428_16200	COG2815	serine threonine protein kinase
Asp14428_16200	COG0515	serine threonine protein kinase
Asp14428_16260	COG4977	sequence-specific DNA binding
Asp14428_16390	COG4591	ABC-type transport system involved in lipoprotein release permease component
Asp14428_16390	COG1136	(ABC) transporter
Asp14428_16400	COG1136	(ABC) transporter
Asp14428_16400	COG0577	efflux transmembrane transporter activity
Asp14428_16470	COG0129	dihydroxy-acid dehydratase activity
Asp14428_16480	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_16520	COG1404	Belongs to the peptidase S8 family
Asp14428_16530	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_16570	COG2197	response regulator
Asp14428_16640	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Asp14428_16650	COG1918	ferrous iron import across plasma membrane
Asp14428_16650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Asp14428_16660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Asp14428_16660	COG1918	ferrous iron import across plasma membrane
Asp14428_16720	COG1309	transcriptional regulator
Asp14428_16740	COG1129	ABC transporter
Asp14428_16760	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_16770	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_16790	COG0318	PFAM AMP-dependent synthetase and ligase
Asp14428_16810	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_16810	COG0604	alcohol dehydrogenase
Asp14428_16810	COG3321	synthase
Asp14428_16890	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asp14428_16970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_17060	COG3634	alkyl hydroperoxide reductase activity
Asp14428_17100	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_17160	COG0410	ABC transporter
Asp14428_17180	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Asp14428_17200	COG2920	part of a sulfur-relay system
Asp14428_17220	COG1937	Protein conserved in bacteria
Asp14428_17230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asp14428_17230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asp14428_17240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asp14428_17300	COG3842	ATPase activity
Asp14428_17350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asp14428_17360	COG1960	acyl-CoA dehydrogenase activity
Asp14428_17370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_17380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_17390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_17400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_17410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asp14428_17500	COG0475	glutathione-regulated potassium exporter activity
Asp14428_17540	COG1063	alcohol dehydrogenase
Asp14428_17610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Asp14428_17630	COG0642	Histidine kinase
Asp14428_17640	COG0745	RESPONSE REGULATOR receiver
Asp14428_17660	COG3507	Belongs to the glycosyl hydrolase 43 family
Asp14428_17660	COG2382	esterase
Asp14428_17660	COG3693	PFAM glycoside hydrolase, family 10
Asp14428_17760	COG1116	anion transmembrane transporter activity
Asp14428_17770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_17780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_17870	COG4585	Histidine kinase
Asp14428_17890	COG1024	Enoyl-CoA hydratase
Asp14428_17890	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asp14428_17980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_18010	COG1132	(ABC) transporter
Asp14428_18080	COG1063	alcohol dehydrogenase
Asp14428_18160	COG2197	response regulator
Asp14428_18170	COG4585	Histidine kinase
Asp14428_18180	COG2409	Drug exporters of the RND superfamily
Asp14428_18230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asp14428_18230	COG1017	nitric oxide dioxygenase activity
Asp14428_18250	COG0745	RESPONSE REGULATOR receiver
Asp14428_18330	COG2072	flavoprotein involved in K transport
Asp14428_18410	COG3903	Transcriptional regulator
Asp14428_18410	COG3629	intracellular signal transduction
Asp14428_18470	COG0681	Belongs to the peptidase S26 family
Asp14428_18550	COG3473	Maleate cis-trans isomerase
Asp14428_18590	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_18600	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Asp14428_18640	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_18650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asp14428_18700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Asp14428_18710	COG1121	(ABC) transporter
Asp14428_18720	COG0803	Belongs to the bacterial solute-binding protein 9 family
Asp14428_18790	COG0803	Belongs to the bacterial solute-binding protein 9 family
Asp14428_18810	COG1121	(ABC) transporter
Asp14428_18820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Asp14428_18870	COG2072	flavoprotein involved in K transport
Asp14428_18880	COG2072	flavoprotein involved in K transport
Asp14428_18930	COG1674	ftsk spoiiie
Asp14428_19010	COG0259	pyridoxamine-phosphate oxidase activity
Asp14428_19140	COG1518	maintenance of DNA repeat elements
Asp14428_19140	COG1468	defense response to virus
Asp14428_19150	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Asp14428_19260	COG3619	membrane
Asp14428_19270	COG0405	Gamma-glutamyltransferase
Asp14428_19290	COG0436	Aminotransferase
Asp14428_19300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Asp14428_19310	COG0577	efflux transmembrane transporter activity
Asp14428_19310	COG1136	(ABC) transporter
Asp14428_19350	COG2409	Drug exporters of the RND superfamily
Asp14428_19360	COG4585	Histidine kinase
Asp14428_19370	COG2197	response regulator
Asp14428_19430	COG0745	RESPONSE REGULATOR receiver
Asp14428_19510	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_19540	COG2124	cytochrome p450
Asp14428_19570	COG0604	alcohol dehydrogenase
Asp14428_19570	COG3321	synthase
Asp14428_19580	COG0604	alcohol dehydrogenase
Asp14428_19580	COG3321	synthase
Asp14428_19590	COG0604	alcohol dehydrogenase
Asp14428_19590	COG3321	synthase
Asp14428_19640	COG0604	alcohol dehydrogenase
Asp14428_19640	COG3321	synthase
Asp14428_19680	COG0604	alcohol dehydrogenase
Asp14428_19680	COG3321	synthase
Asp14428_19690	COG0604	alcohol dehydrogenase
Asp14428_19690	COG3321	synthase
Asp14428_19690	COG3321	synthase
Asp14428_19690	COG0604	alcohol dehydrogenase
Asp14428_19710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Asp14428_19720	COG0604	alcohol dehydrogenase
Asp14428_19740	COG3320	Male sterility
Asp14428_19740	COG1022	Amp-dependent synthetase and ligase
Asp14428_19770	COG3321	synthase
Asp14428_19770	COG0604	alcohol dehydrogenase
Asp14428_19770	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_19800	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_19840	COG0589	response to stress
Asp14428_19890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asp14428_19950	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_19960	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asp14428_19960	COG1024	Enoyl-CoA hydratase
Asp14428_19990	COG1404	Belongs to the peptidase S8 family
Asp14428_20020	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asp14428_20020	COG1672	PFAM Archaeal ATPase
Asp14428_20060	COG4221	oxidoreductase activity
Asp14428_20070	COG3706	GGDEF domain
Asp14428_20110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Asp14428_20260	COG2080	2 iron, 2 sulfur cluster binding
Asp14428_20270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Asp14428_20280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Asp14428_20330	COG0492	ferredoxin-NADP+ reductase activity
Asp14428_20340	COG0477	Major facilitator Superfamily
Asp14428_20370	COG2132	Multicopper oxidase
Asp14428_20370	COG2132	Multicopper oxidase
Asp14428_20390	COG2159	amidohydrolase
Asp14428_20410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Asp14428_20460	COG1672	PFAM Archaeal ATPase
Asp14428_20460	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asp14428_20490	COG3903	Transcriptional regulator
Asp14428_20490	COG3629	intracellular signal transduction
Asp14428_20500	COG1802	Transcriptional regulator
Asp14428_20510	COG0247	lactate metabolic process
Asp14428_20510	COG0277	FAD linked oxidase domain protein
Asp14428_20590	COG1473	amidohydrolase
Asp14428_20600	COG0515	serine threonine protein kinase
Asp14428_20600	COG2815	serine threonine protein kinase
Asp14428_20650	COG3973	AAA domain
Asp14428_20700	COG2205	protein histidine kinase activity
Asp14428_20710	COG0583	DNA-binding transcription factor activity
Asp14428_20740	COG0372	Belongs to the citrate synthase family
Asp14428_20790	COG1131	(ABC) transporter
Asp14428_20920	COG3033	Beta-eliminating lyase
Asp14428_20930	COG3033	Beta-eliminating lyase
Asp14428_20940	COG3033	Beta-eliminating lyase
Asp14428_21010	COG2837	iron assimilation
Asp14428_21130	COG1309	transcriptional regulator
Asp14428_21290	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Asp14428_21320	COG0745	RESPONSE REGULATOR receiver
Asp14428_21340	COG2375	cellular response to nickel ion
Asp14428_21340	COG1132	(ABC) transporter
Asp14428_21400	COG1714	RDD family
Asp14428_21440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asp14428_21480	COG1116	anion transmembrane transporter activity
Asp14428_21490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_21500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Asp14428_21510	COG2186	Transcriptional regulator
Asp14428_21550	COG1960	acyl-CoA dehydrogenase activity
Asp14428_21570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asp14428_21580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Asp14428_21590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Asp14428_21600	COG0189	ligase activity
Asp14428_21620	COG3958	Transketolase
Asp14428_21630	COG3959	Transketolase, thiamine diphosphate binding domain
Asp14428_21640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asp14428_21700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_21710	COG0137	argininosuccinate synthase activity
Asp14428_21720	COG2197	response regulator
Asp14428_21730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asp14428_21750	COG3903	Transcriptional regulator
Asp14428_21750	COG3629	intracellular signal transduction
Asp14428_21930	COG1595	DNA-templated transcription, initiation
Asp14428_22040	COG0577	efflux transmembrane transporter activity
Asp14428_22040	COG1136	(ABC) transporter
Asp14428_22070	COG0745	RESPONSE REGULATOR receiver
Asp14428_22080	COG2205	protein histidine kinase activity
Asp14428_22170	COG0714	Associated with various cellular activities
Asp14428_22210	COG1404	Belongs to the peptidase S8 family
Asp14428_22220	COG2226	methyltransferase
Asp14428_22260	COG0671	phosphoesterase, PA-phosphatase related
Asp14428_22280	COG2208	phosphoserine phosphatase activity
Asp14428_22280	COG2770	Histidine kinase
Asp14428_22320	COG0745	RESPONSE REGULATOR receiver
Asp14428_22330	COG4251	negative regulation of phosphorylation
Asp14428_22360	COG0436	Aminotransferase
Asp14428_22370	COG2202	Pas domain
Asp14428_22370	COG2205	protein histidine kinase activity
Asp14428_22400	COG4682	membrane
Asp14428_22480	COG0477	Major facilitator Superfamily
Asp14428_22520	COG0604	alcohol dehydrogenase
Asp14428_22540	COG0667	Aldo Keto reductase
Asp14428_22690	COG4585	Histidine kinase
Asp14428_22700	COG2197	response regulator
Asp14428_22750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asp14428_22750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asp14428_22770	COG0745	RESPONSE REGULATOR receiver
Asp14428_22780	COG2146	nitrite reductase [NAD(P)H] activity
Asp14428_22780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Asp14428_22820	COG1215	transferase activity, transferring glycosyl groups
Asp14428_22830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Asp14428_22840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asp14428_22850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Asp14428_22860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Asp14428_22870	COG1215	transferase activity, transferring glycosyl groups
Asp14428_22890	COG3903	Transcriptional regulator
Asp14428_22890	COG3629	intracellular signal transduction
Asp14428_22910	COG0395	ABC-type sugar transport system, permease component
Asp14428_22920	COG1175	transmembrane transport
Asp14428_22930	COG1653	transport
Asp14428_22940	COG1737	Transcriptional regulator
Asp14428_22950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Asp14428_22960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Asp14428_22970	COG1365	unkown
Asp14428_23110	COG1595	DNA-templated transcription, initiation
Asp14428_23190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asp14428_23230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Asp14428_23280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Asp14428_23290	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_23360	COG4191	Histidine kinase
Asp14428_23370	COG4251	negative regulation of phosphorylation
Asp14428_23460	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asp14428_23470	COG2304	oxidoreductase activity
Asp14428_23490	COG0714	Associated with various cellular activities
Asp14428_23570	COG0006	proline dipeptidase activity
Asp14428_23620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Asp14428_23680	COG1309	transcriptional regulator
Asp14428_23700	COG3220	belongs to the UPF0276 family
Asp14428_23780	COG1132	(ABC) transporter
Asp14428_23790	COG1024	Enoyl-CoA hydratase
Asp14428_23810	COG0488	(ABC) transporter
Asp14428_23820	COG2321	neutral zinc metallopeptidase
Asp14428_23840	COG0330	HflC and HflK could
Asp14428_23920	COG2151	metal-sulfur cluster biosynthetic enzyme
Asp14428_23930	COG0822	iron-sulfur transferase activity
Asp14428_23940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asp14428_23950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asp14428_23960	COG0396	ATPase activity
Asp14428_23980	COG0719	Fe-S assembly protein
Asp14428_24010	COG1612	heme a metabolic process
Asp14428_24030	COG0109	protoheme IX farnesyltransferase activity
Asp14428_24050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Asp14428_24080	COG0363	glucosamine-6-phosphate deaminase activity
Asp14428_24130	COG0456	acetyltransferase
Asp14428_24150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Asp14428_24160	COG0149	triose-phosphate isomerase activity
Asp14428_24170	COG0126	phosphoglycerate kinase activity
Asp14428_24180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Asp14428_24190	COG3226	Transcriptional regulator
Asp14428_24200	COG1472	Belongs to the glycosyl hydrolase 3 family
Asp14428_24210	COG2223	nitrite transmembrane transporter activity
Asp14428_24220	COG1481	regulation of sporulation
Asp14428_24240	COG1660	Displays ATPase and GTPase activities
Asp14428_24250	COG0322	excinuclease ABC activity
Asp14428_24270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Asp14428_24290	COG1162	GTPase activity
Asp14428_24310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asp14428_24320	COG1335	isochorismatase
Asp14428_24330	COG0740	serine-type endopeptidase activity
Asp14428_24340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Asp14428_24350	COG1217	gtp-binding protein TYPA
Asp14428_24400	COG0237	dephospho-CoA kinase activity
Asp14428_24400	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Asp14428_24420	COG0539	negative regulation of cytoplasmic translation
Asp14428_24430	COG2226	methyltransferase
Asp14428_24480	COG0683	leucine binding
Asp14428_24520	COG0559	Belongs to the binding-protein-dependent transport system permease family
Asp14428_24610	COG0067	glutamate synthase
Asp14428_24610	COG0070	glutamate synthase
Asp14428_24610	COG0069	glutamate synthase activity
Asp14428_24630	COG0463	Glycosyl transferase, family 2
Asp14428_24660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Asp14428_24670	COG0159	tryptophan synthase activity
Asp14428_24680	COG0133	tryptophan synthase activity
Asp14428_24690	COG0134	indole-3-glycerol-phosphate synthase activity
Asp14428_24730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Asp14428_24790	COG0842	Transport permease protein
Asp14428_24820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Asp14428_24830	COG1132	(ABC) transporter
Asp14428_24840	COG1132	(ABC) transporter
Asp14428_24870	COG0745	RESPONSE REGULATOR receiver
Asp14428_24880	COG2205	protein histidine kinase activity
Asp14428_24910	COG1022	Amp-dependent synthetase and ligase
Asp14428_24960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asp14428_24990	COG0107	imidazoleglycerol-phosphate synthase activity
Asp14428_25010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Asp14428_25030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Asp14428_25050	COG0131	Imidazoleglycerol-phosphate dehydratase
Asp14428_25060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asp14428_25070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Asp14428_25080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Asp14428_25100	COG0587	DNA-directed DNA polymerase activity
Asp14428_25140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Asp14428_25220	COG1799	cell septum assembly
Asp14428_25240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Asp14428_25250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Asp14428_25260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Asp14428_25270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Asp14428_25280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asp14428_25300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Asp14428_25320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Asp14428_25330	COG0768	penicillin binding
Asp14428_25350	COG0275	rRNA processing
Asp14428_25370	COG2001	Belongs to the MraZ family
Asp14428_25400	COG3442	glutamine amidotransferase
Asp14428_25420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Asp14428_25430	COG0495	leucyl-tRNA aminoacylation
Asp14428_25440	COG0714	Associated with various cellular activities
Asp14428_25480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Asp14428_25660	COG0583	DNA-binding transcription factor activity
Asp14428_25680	COG1053	succinate dehydrogenase
Asp14428_25690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Asp14428_25780	COG0142	geranyltranstransferase activity
Asp14428_25830	COG2815	serine threonine protein kinase
Asp14428_25830	COG0515	serine threonine protein kinase
Asp14428_25840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Asp14428_25870	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Asp14428_25900	COG0386	Belongs to the glutathione peroxidase family
Asp14428_25940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Asp14428_26060	COG2072	flavoprotein involved in K transport
Asp14428_26080	COG1940	carbohydrate kinase activity
Asp14428_26170	COG1132	(ABC) transporter
Asp14428_26190	COG0438	transferase activity, transferring glycosyl groups
Asp14428_26200	COG0438	transferase activity, transferring glycosyl groups
Asp14428_26210	COG0501	Belongs to the peptidase M48B family
Asp14428_26270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asp14428_26290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Asp14428_26310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Asp14428_26330	COG2010	Cytochrome c
Asp14428_26370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Asp14428_26410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Asp14428_26420	COG1104	cysteine desulfurase activity
Asp14428_26450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asp14428_26490	COG1929	Belongs to the glycerate kinase type-1 family
Asp14428_26510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Asp14428_26520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asp14428_26550	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Asp14428_26570	COG4555	ABC transporter
Asp14428_26630	COG0667	Aldo Keto reductase
Asp14428_26640	COG1994	Peptidase M50
Asp14428_26660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Asp14428_26680	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Asp14428_26690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Asp14428_26700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Asp14428_26710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Asp14428_26730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asp14428_26740	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asp14428_26750	COG1090	epimerase
Asp14428_26770	COG0321	lipoyl(octanoyl) transferase activity
Asp14428_26790	COG0017	Asparaginyl-tRNA synthetase
Asp14428_26800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Asp14428_26810	COG1672	PFAM Archaeal ATPase
Asp14428_26810	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asp14428_26930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Asp14428_26940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Asp14428_26960	COG3766	membrane
Asp14428_26970	COG0174	glutamine synthetase
Asp14428_26980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Asp14428_26980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Asp14428_26990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Asp14428_27070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asp14428_27090	COG0583	DNA-binding transcription factor activity
Asp14428_27140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asp14428_27190	COG1846	Transcriptional regulator
Asp14428_27290	COG1674	ftsk spoiiie
Asp14428_27340	COG0730	response to heat
Asp14428_27410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Asp14428_27470	COG0492	ferredoxin-NADP+ reductase activity
Asp14428_27500	COG2814	Major facilitator Superfamily
Asp14428_27520	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_27560	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Asp14428_27630	COG0432	Pfam Uncharacterised protein family UPF0047
Asp14428_27640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Asp14428_27650	COG0840	transmembrane signaling receptor activity
Asp14428_27660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Asp14428_27680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Asp14428_27760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asp14428_27770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Asp14428_27780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asp14428_27840	COG2267	carboxylic ester hydrolase activity
Asp14428_27850	COG3973	AAA domain
Asp14428_27910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Asp14428_27920	COG0515	serine threonine protein kinase
Asp14428_27960	COG0515	serine threonine protein kinase
Asp14428_27990	COG0737	Belongs to the 5'-nucleotidase family
Asp14428_28080	COG0714	Associated with various cellular activities
Asp14428_28110	COG1268	BioY protein
Asp14428_28140	COG0018	arginyl-trna synthetase
Asp14428_28170	COG0840	transmembrane signaling receptor activity
Asp14428_28180	COG0840	transmembrane signaling receptor activity
Asp14428_28230	COG2197	response regulator
Asp14428_28240	COG1672	PFAM Archaeal ATPase
Asp14428_28240	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asp14428_28340	COG1102	Psort location Cytoplasmic, score
Asp14428_28340	COG1904	glucuronate isomerase
Asp14428_28350	COG3250	beta-galactosidase activity
Asp14428_28390	COG0246	Mannitol dehydrogenase
Asp14428_28400	COG1904	glucuronate isomerase
Asp14428_28420	COG1609	Transcriptional regulator
Asp14428_28440	COG1606	tRNA processing
Asp14428_28450	COG1691	(AIR) carboxylase
Asp14428_28460	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Asp14428_28470	COG1733	regulation of RNA biosynthetic process
Asp14428_28530	COG4977	sequence-specific DNA binding
Asp14428_28590	COG0477	Major facilitator Superfamily
Asp14428_28620	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Asp14428_28620	COG4124	Belongs to the glycosyl hydrolase 26 family
Asp14428_28640	COG2205	protein histidine kinase activity
Asp14428_28650	COG0745	RESPONSE REGULATOR receiver
Asp14428_28670	COG0577	efflux transmembrane transporter activity
Asp14428_28670	COG1136	(ABC) transporter
Asp14428_28730	COG0395	ABC-type sugar transport system, permease component
Asp14428_28770	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_28800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Asp14428_28820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Asp14428_28860	COG0577	efflux transmembrane transporter activity
Asp14428_29010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Asp14428_29020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Asp14428_29110	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
Asp14428_29150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Asp14428_29180	COG0747	negative chemotaxis
Asp14428_29210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asp14428_29210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asp14428_29250	COG0277	FAD linked oxidase domain protein
Asp14428_29380	COG2197	response regulator
Asp14428_29390	COG4585	Histidine kinase
Asp14428_29450	COG2197	response regulator
Asp14428_29460	COG4585	Histidine kinase
Asp14428_29570	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_29580	COG1129	ABC transporter
Asp14428_29640	COG1131	(ABC) transporter
Asp14428_29660	COG0358	DNA primase activity
Asp14428_29670	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Asp14428_29720	COG2018	Roadblock/LC7 domain
Asp14428_29750	COG3608	succinylglutamate desuccinylase aspartoacylase
Asp14428_29750	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Asp14428_29760	COG2259	Doxx family
Asp14428_29770	COG0423	glycine-tRNA ligase activity
Asp14428_29820	COG0803	Belongs to the bacterial solute-binding protein 9 family
Asp14428_29820	COG3443	Belongs to the bacterial solute-binding protein 9 family
Asp14428_29830	COG1121	(ABC) transporter
Asp14428_29840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Asp14428_29900	COG4721	ABC-type cobalt transport system, permease component
Asp14428_29920	COG1122	ATPase activity
Asp14428_30000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Asp14428_30010	COG1381	Involved in DNA repair and RecF pathway recombination
Asp14428_30030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Asp14428_30070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Asp14428_30100	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_30130	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Asp14428_30200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Asp14428_30340	COG1132	(ABC) transporter
Asp14428_30350	COG1132	(ABC) transporter
Asp14428_30370	COG1120	ATPase activity
Asp14428_30380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asp14428_30390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asp14428_30410	COG0484	heat shock protein binding
Asp14428_30420	COG1420	regulation of RNA biosynthetic process
Asp14428_30440	COG1404	Belongs to the peptidase S8 family
Asp14428_30460	COG1024	Enoyl-CoA hydratase
Asp14428_30510	COG0481	GTPase activity
Asp14428_30570	COG0268	Binds directly to 16S ribosomal RNA
Asp14428_30600	COG3537	Alpha-1,2-mannosidase
Asp14428_30630	COG2333	competence protein COMEC
Asp14428_30630	COG0658	competence protein
Asp14428_30640	COG1555	photosystem II stabilization
Asp14428_30640	COG1596	polysaccharide export
Asp14428_30650	COG2890	protein-(glutamine-N5) methyltransferase activity
Asp14428_30670	COG1307	EDD domain protein, DegV family
Asp14428_30690	COG0406	alpha-ribazole phosphatase activity
Asp14428_30700	COG0799	negative regulation of ribosome biogenesis
Asp14428_30710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Asp14428_30760	COG0454	-acetyltransferase
Asp14428_30770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Asp14428_30790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Asp14428_30800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Asp14428_30820	COG1530	ribonuclease E activity
Asp14428_30860	COG1366	Belongs to the anti-sigma-factor antagonist family
Asp14428_30860	COG2208	phosphoserine phosphatase activity
Asp14428_30860	COG2172	sigma factor antagonist activity
Asp14428_30870	COG0596	Alpha beta hydrolase
Asp14428_30900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Asp14428_30920	COG0105	UTP biosynthetic process
Asp14428_30980	COG0285	dihydrofolate synthase activity
Asp14428_30990	COG0525	valine-tRNA ligase activity
Asp14428_31040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Asp14428_31050	COG0740	serine-type endopeptidase activity
Asp14428_31060	COG0740	serine-type endopeptidase activity
Asp14428_31070	COG0544	peptidyl-prolyl cis-trans isomerase activity
Asp14428_31120	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_31130	COG2340	Cysteine-rich secretory protein family
Asp14428_31150	COG0640	Transcriptional regulator
Asp14428_31180	COG4552	Acetyltransferase involved in intracellular survival and related
Asp14428_31260	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Asp14428_31320	COG0668	transmembrane transport
Asp14428_31420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Asp14428_31440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Asp14428_31440	COG1648	precorrin-2 dehydrogenase activity
Asp14428_31450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Asp14428_31490	COG1797	cobyrinic acid a,c-diamide synthase activity
Asp14428_31520	COG1793	dna ligase
Asp14428_31580	COG0501	Belongs to the peptidase M48B family
Asp14428_31600	COG1492	cobalamin metabolic process
Asp14428_31610	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Asp14428_31620	COG0629	single-stranded DNA binding
Asp14428_31650	COG0577	efflux transmembrane transporter activity
Asp14428_31650	COG1136	(ABC) transporter
Asp14428_31760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asp14428_31780	COG2197	response regulator
Asp14428_31930	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_31940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Asp14428_31990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asp14428_32000	COG0366	Alpha amylase catalytic
Asp14428_32020	COG1070	Carbohydrate kinase
Asp14428_32030	COG2115	Belongs to the xylose isomerase family
Asp14428_32080	COG2706	6-phosphogluconolactonase activity
Asp14428_32220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_32270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Asp14428_32310	COG3647	Membrane
Asp14428_32340	COG0784	Response regulator, receiver
Asp14428_32400	COG1376	ErfK ybiS ycfS ynhG family protein
Asp14428_32410	COG1376	ErfK ybiS ycfS ynhG family protein
Asp14428_32440	COG3621	Patatin-like phospholipase
Asp14428_32510	COG0582	viral genome integration into host DNA
Asp14428_32530	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Asp14428_32830	COG1652	LysM domain
Asp14428_32840	COG0443	Heat shock 70 kDa protein
Asp14428_32970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Asp14428_33190	COG3344	reverse transcriptase
Asp14428_33240	COG1674	ftsk spoiiie
Asp14428_33360	COG3335	DDE superfamily endonuclease
Asp14428_33670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asp14428_33700	COG0667	Aldo Keto reductase
Asp14428_33720	COG2318	DinB family
Asp14428_33740	COG2936	dipeptidyl-peptidase activity
Asp14428_33760	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Asp14428_33780	COG0583	DNA-binding transcription factor activity
Asp14428_33980	COG1487	ribonuclease activity
Asp14428_33990	COG4691	Plasmid stability protein
Asp14428_34010	COG1073	alpha beta
Asp14428_34030	COG2314	TM2 domain
Asp14428_34060	COG0789	Transcriptional regulator
Asp14428_34260	COG1366	Belongs to the anti-sigma-factor antagonist family
Asp14428_34310	COG3795	YCII-related domain
Asp14428_34320	COG4941	Belongs to the sigma-70 factor family
Asp14428_34350	COG2894	cell division
Asp14428_34380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Asp14428_34390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asp14428_34410	COG1228	amidohydrolase
Asp14428_34420	COG2986	histidine ammonia-lyase
Asp14428_34460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Asp14428_34470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Asp14428_34480	COG0438	transferase activity, transferring glycosyl groups
Asp14428_34490	COG1234	tRNA 3'-trailer cleavage
Asp14428_34540	COG0667	Aldo Keto reductase
Asp14428_34590	COG2197	response regulator
Asp14428_34600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Asp14428_34610	COG1335	isochorismatase
Asp14428_34630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Asp14428_34640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asp14428_34660	COG1793	dna ligase
Asp14428_34660	COG3285	dna ligase
Asp14428_34670	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Asp14428_34700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asp14428_34740	COG1846	Transcriptional regulator
Asp14428_34760	COG2200	EAL domain
Asp14428_34810	COG0300	oxidoreductase activity
Asp14428_34930	COG0667	Aldo Keto reductase
Asp14428_35090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Asp14428_35110	COG1459	type II secretion system
Asp14428_35120	COG2165	general secretion pathway protein
Asp14428_35130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Asp14428_35270	COG0438	transferase activity, transferring glycosyl groups
Asp14428_35300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Asp14428_35300	COG2755	lipolytic protein G-D-S-L family
Asp14428_35320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asp14428_35340	COG0489	protein tyrosine kinase activity
Asp14428_35340	COG3206	protein involved in exopolysaccharide biosynthesis
Asp14428_35350	COG1086	Polysaccharide biosynthesis protein
Asp14428_35460	COG1678	Uncharacterized ACR, COG1678
Asp14428_35470	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Asp14428_35510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Asp14428_35550	COG2884	Cell division ATP-binding protein ftsE
Asp14428_35560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Asp14428_35580	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_35630	COG0653	protein targeting
Asp14428_35650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asp14428_35660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Asp14428_35690	COG5002	protein histidine kinase activity
Asp14428_35710	COG0745	RESPONSE REGULATOR receiver
Asp14428_35720	COG2837	iron assimilation
Asp14428_35740	COG0672	)-iron permease
Asp14428_35770	COG1482	cell wall glycoprotein biosynthetic process
Asp14428_35800	COG2835	tetraacyldisaccharide 4'-kinase activity
Asp14428_35810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asp14428_35820	COG1515	deoxyribonuclease V activity
Asp14428_35840	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_35850	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_35890	COG0726	polysaccharide deacetylase
Asp14428_35930	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Asp14428_35950	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Asp14428_35960	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
Asp14428_35960	COG0778	Nitroreductase
Asp14428_35980	COG0662	Cupin 2, conserved barrel domain protein
Asp14428_35980	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Asp14428_36020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asp14428_36080	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Asp14428_36130	COG1331	Highly conserved protein containing a thioredoxin domain
Asp14428_36190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asp14428_36210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Asp14428_36220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asp14428_36260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asp14428_36300	COG3025	triphosphatase activity
Asp14428_36300	COG5607	PFAM CHAD domain containing protein
Asp14428_36310	COG2326	polyphosphate kinase activity
Asp14428_36320	COG2326	polyphosphate kinase activity
Asp14428_36330	COG1234	tRNA 3'-trailer cleavage
Asp14428_36340	COG0456	acetyltransferase
Asp14428_36400	COG2755	lipolytic protein G-D-S-L family
Asp14428_36410	COG0183	Belongs to the thiolase family
Asp14428_36420	COG0183	Belongs to the thiolase family
Asp14428_36460	COG1309	transcriptional regulator
Asp14428_36490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asp14428_36540	COG3835	regulator
Asp14428_36600	COG1252	NADH dehydrogenase
Asp14428_36630	COG0714	Associated with various cellular activities
Asp14428_36790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Asp14428_36820	COG0148	phosphopyruvate hydratase activity
Asp14428_36910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asp14428_36960	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Asp14428_36980	COG1595	DNA-templated transcription, initiation
Asp14428_37090	COG0529	Catalyzes the synthesis of activated sulfate
Asp14428_37170	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Asp14428_37200	COG1349	DNA-binding transcription factor activity
Asp14428_37220	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_37220	COG1454	alcohol dehydrogenase
Asp14428_37230	COG0538	isocitrate dehydrogenase activity
Asp14428_37280	COG0138	bifunctional purine biosynthesis protein purh
Asp14428_37330	COG0045	succinate-CoA ligase (ADP-forming) activity
Asp14428_37340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asp14428_37360	COG1196	nuclear chromosome segregation
Asp14428_37360	COG0741	lytic transglycosylase activity
Asp14428_37360	COG0739	heme binding
Asp14428_37380	COG0737	Belongs to the 5'-nucleotidase family
Asp14428_37380	COG1525	nuclease
Asp14428_37380	COG4085	toxin activity
Asp14428_37390	COG1605	Chorismate mutase
Asp14428_37400	COG4608	Belongs to the ABC transporter superfamily
Asp14428_37420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asp14428_37440	COG4166	transmembrane transport
Asp14428_37450	COG4166	transmembrane transport
Asp14428_37460	COG2197	response regulator
Asp14428_37510	COG0688	phosphatidylethanolamine metabolic process
Asp14428_37520	COG1183	phosphatidylcholine synthase activity
Asp14428_37540	COG1051	belongs to the nudix hydrolase family
Asp14428_37560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Asp14428_37560	COG0519	Catalyzes the synthesis of GMP from XMP
Asp14428_37620	COG0516	GMP reductase activity
Asp14428_37650	COG2197	response regulator
Asp14428_37700	COG0459	protein refolding
Asp14428_37710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Asp14428_37730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Asp14428_37760	COG4214	carbohydrate transport
Asp14428_37790	COG1132	(ABC) transporter
Asp14428_37800	COG1132	(ABC) transporter
Asp14428_37820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Asp14428_37830	COG0456	acetyltransferase
Asp14428_37850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Asp14428_37860	COG0802	atpase or kinase
Asp14428_37880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Asp14428_37900	COG0736	holo-[acyl-carrier-protein] synthase activity
Asp14428_37930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asp14428_37970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asp14428_37980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Asp14428_37990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Asp14428_38040	COG2018	Roadblock/LC7 domain
Asp14428_38070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_38080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Asp14428_38150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Asp14428_38160	COG0351	phosphomethylpyrimidine kinase
Asp14428_38170	COG0352	thiamine-phosphate diphosphorylase activity
Asp14428_38180	COG2022	thiamine diphosphate biosynthetic process
Asp14428_38200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asp14428_38200	COG2022	thiamine diphosphate biosynthetic process
Asp14428_38210	COG0352	thiamine-phosphate diphosphorylase activity
Asp14428_38220	COG0488	(ABC) transporter
Asp14428_38230	COG2813	Specifically methylates the guanine in position
Asp14428_38250	COG0101	tRNA pseudouridine synthase activity
Asp14428_38260	COG0203	ribosomal protein L17
Asp14428_38280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Asp14428_38290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Asp14428_38300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Asp14428_38310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Asp14428_38360	COG0563	adenylate kinase activity
Asp14428_38380	COG0200	Binds to the 23S rRNA
Asp14428_38390	COG1841	ribosomal large subunit assembly
Asp14428_38400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Asp14428_38410	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Asp14428_38420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Asp14428_38430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Asp14428_38440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Asp14428_38450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Asp14428_38460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Asp14428_38470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Asp14428_38480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Asp14428_38490	COG0255	Belongs to the universal ribosomal protein uL29 family
Asp14428_38500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Asp14428_38510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Asp14428_38520	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Asp14428_38530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Asp14428_38540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Asp14428_38560	COG0088	Forms part of the polypeptide exit tunnel
Asp14428_38570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Asp14428_38580	COG0051	transcription antitermination factor activity, RNA binding
Asp14428_38590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Asp14428_38600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Asp14428_38610	COG0049	tRNA binding
Asp14428_38620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Asp14428_38650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Asp14428_38660	COG0085	RNA polymerase activity
Asp14428_38670	COG0222	ribosome binding
Asp14428_38710	COG0081	regulation of translation
Asp14428_38730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Asp14428_38750	COG2030	dehydratase
Asp14428_38760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Asp14428_38910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_38960	COG2188	Transcriptional regulator
Asp14428_38980	COG0501	Belongs to the peptidase M48B family
Asp14428_39000	COG1007	ATP synthesis coupled electron transport
Asp14428_39010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asp14428_39020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Asp14428_39030	COG0713	ATP synthesis coupled electron transport
Asp14428_39050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asp14428_39060	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Asp14428_39090	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asp14428_39150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Asp14428_39170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Asp14428_39180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Asp14428_39230	COG0596	Alpha beta hydrolase
Asp14428_39270	COG0513	Belongs to the DEAD box helicase family
Asp14428_39330	COG1937	Protein conserved in bacteria
Asp14428_39340	COG0791	NLP P60 protein
Asp14428_39370	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_39380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Asp14428_39390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Asp14428_39400	COG0569	domain protein
Asp14428_39410	COG2815	serine threonine protein kinase
Asp14428_39410	COG0515	serine threonine protein kinase
Asp14428_39440	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_39450	COG0483	inositol monophosphate 1-phosphatase activity
Asp14428_39460	COG0784	Response regulator, receiver
Asp14428_39470	COG4251	negative regulation of phosphorylation
Asp14428_39480	COG0745	RESPONSE REGULATOR receiver
Asp14428_39570	COG0745	RESPONSE REGULATOR receiver
Asp14428_39580	COG2205	protein histidine kinase activity
Asp14428_39600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Asp14428_39610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Asp14428_39660	COG1414	Transcriptional regulator
Asp14428_39670	COG0402	S-adenosylhomocysteine deaminase activity
Asp14428_39680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asp14428_39740	COG0583	DNA-binding transcription factor activity
Asp14428_39790	COG1131	(ABC) transporter
Asp14428_39840	COG1131	(ABC) transporter
Asp14428_40020	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_40040	COG0673	inositol 2-dehydrogenase activity
Asp14428_40060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_40090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Asp14428_40100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Asp14428_40110	COG0009	L-threonylcarbamoyladenylate synthase
Asp14428_40130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Asp14428_40150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Asp14428_40210	COG0745	RESPONSE REGULATOR receiver
Asp14428_40220	COG5002	protein histidine kinase activity
Asp14428_40270	COG2124	cytochrome p450
Asp14428_40280	COG0242	peptide deformylase activity
Asp14428_40300	COG0501	Belongs to the peptidase M48B family
Asp14428_40310	COG4941	Belongs to the sigma-70 factor family
Asp14428_40320	COG3795	YCII-related domain
Asp14428_40330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Asp14428_40380	COG1556	Lactate utilization protein
Asp14428_40390	COG1139	Iron-sulfur cluster binding protein
Asp14428_40400	COG0247	lactate metabolic process
Asp14428_40410	COG1070	Carbohydrate kinase
Asp14428_40420	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_40420	COG3347	Dehydrogenase
Asp14428_40440	COG1129	ABC transporter
Asp14428_40450	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_40460	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_40480	COG3254	rhamnose metabolic process
Asp14428_40600	COG0604	alcohol dehydrogenase
Asp14428_40610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Asp14428_40720	COG3537	Alpha-1,2-mannosidase
Asp14428_40740	COG2837	iron assimilation
Asp14428_40910	COG1253	flavin adenine dinucleotide binding
Asp14428_40920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asp14428_40940	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asp14428_40940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asp14428_40970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asp14428_40970	COG2213	PTS system mannitol-specific
Asp14428_41050	COG2119	membrane
Asp14428_41120	COG1063	alcohol dehydrogenase
Asp14428_41130	COG0395	ABC-type sugar transport system, permease component
Asp14428_41180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Asp14428_41190	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Asp14428_41230	COG2089	acid synthase
Asp14428_41250	COG1216	Glycosyl transferase, family 2
Asp14428_41330	COG1846	Transcriptional regulator
Asp14428_41350	COG0583	DNA-binding transcription factor activity
Asp14428_41370	COG0463	Glycosyl transferase, family 2
Asp14428_41440	COG1086	Polysaccharide biosynthesis protein
Asp14428_41450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asp14428_41490	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Asp14428_41500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asp14428_41510	COG0242	peptide deformylase activity
Asp14428_41520	COG0745	RESPONSE REGULATOR receiver
Asp14428_41530	COG0477	Major facilitator Superfamily
Asp14428_41540	COG1619	proteins homologs of microcin C7 resistance protein MccF
Asp14428_41550	COG2843	Capsule synthesis protein
Asp14428_41570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Asp14428_41600	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asp14428_41660	COG2197	response regulator
Asp14428_41690	COG3629	intracellular signal transduction
Asp14428_41690	COG3903	Transcriptional regulator
Asp14428_41720	COG0464	growth
Asp14428_41760	COG1674	ftsk spoiiie
Asp14428_41850	COG3209	COG3209 Rhs family protein
Asp14428_41940	COG1129	ABC transporter
Asp14428_41950	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_41960	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_42060	COG3706	GGDEF domain
Asp14428_42110	COG1309	transcriptional regulator
Asp14428_42130	COG1134	teichoic acid transport
Asp14428_42130	COG1388	LysM domain
Asp14428_42210	COG3842	ATPase activity
Asp14428_42220	COG1216	Glycosyl transferase, family 2
Asp14428_42260	COG1960	acyl-CoA dehydrogenase activity
Asp14428_42280	COG0778	Nitroreductase
Asp14428_42280	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
Asp14428_42290	COG2017	converts alpha-aldose to the beta-anomer
Asp14428_42310	COG0259	pyridoxamine-phosphate oxidase activity
Asp14428_42330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Asp14428_42340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asp14428_42370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Asp14428_42390	COG2807	transmembrane transport
Asp14428_42400	COG2186	Transcriptional regulator
Asp14428_42430	COG2814	Major facilitator Superfamily
Asp14428_42450	COG2252	PERMEase
Asp14428_42480	COG2814	Major facilitator Superfamily
Asp14428_42490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Asp14428_42500	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Asp14428_42510	COG1278	Cold shock
Asp14428_42520	COG0546	phosphoglycolate phosphatase activity
Asp14428_42550	COG1061	Type III restriction enzyme res subunit
Asp14428_42580	COG3285	dna ligase
Asp14428_42580	COG1793	dna ligase
Asp14428_42590	COG3285	dna ligase
Asp14428_42590	COG1793	dna ligase
Asp14428_42600	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Asp14428_42630	COG0110	maltose O-acetyltransferase activity
Asp14428_42640	COG3226	Transcriptional regulator
Asp14428_42650	COG0738	Major facilitator superfamily
Asp14428_42740	COG0693	protein deglycase activity
Asp14428_42820	COG2801	Transposase and inactivated derivatives
Asp14428_42870	COG0582	viral genome integration into host DNA
Asp14428_42980	COG1774	PSP1 C-terminal conserved region
Asp14428_43040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Asp14428_43050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Asp14428_43070	COG1309	transcriptional regulator
Asp14428_43090	COG1754	DNA topoisomerase type I activity
Asp14428_43090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Asp14428_43120	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Asp14428_43130	COG2172	sigma factor antagonist activity
Asp14428_43140	COG1366	Belongs to the anti-sigma-factor antagonist family
Asp14428_43150	COG1205	dead DEAH box helicase
Asp14428_43150	COG1111	helicase
Asp14428_43280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asp14428_43330	COG0596	Alpha beta hydrolase
Asp14428_43430	COG1950	PFAM Membrane protein of
Asp14428_43490	COG0142	geranyltranstransferase activity
Asp14428_43500	COG1007	ATP synthesis coupled electron transport
Asp14428_43530	COG0713	ATP synthesis coupled electron transport
Asp14428_43550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asp14428_43560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Asp14428_43570	COG1034	ATP synthesis coupled electron transport
Asp14428_43580	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Asp14428_43600	COG0649	NAD binding
Asp14428_43610	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asp14428_43620	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asp14428_43670	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Asp14428_43680	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Asp14428_43710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Asp14428_43720	COG4279	zinc finger
Asp14428_43740	COG0667	Aldo Keto reductase
Asp14428_43780	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Asp14428_43790	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Asp14428_43800	COG3973	AAA domain
Asp14428_43840	COG1131	(ABC) transporter
Asp14428_43870	COG1120	ATPase activity
Asp14428_43880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asp14428_43890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Asp14428_43930	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Asp14428_43940	COG0791	NLP P60 protein
Asp14428_43980	COG0513	Belongs to the DEAD box helicase family
Asp14428_44010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Asp14428_44020	COG1522	sequence-specific DNA binding
Asp14428_44040	COG0163	prenyltransferase activity
Asp14428_44080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Asp14428_44100	COG1609	Transcriptional regulator
Asp14428_44110	COG0366	Alpha amylase catalytic
Asp14428_44150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Asp14428_44170	COG0785	Cytochrome C biogenesis protein
Asp14428_44180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asp14428_44190	COG0406	alpha-ribazole phosphatase activity
Asp14428_44200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Asp14428_44210	COG1366	Belongs to the anti-sigma-factor antagonist family
Asp14428_44230	COG0784	Response regulator, receiver
Asp14428_44230	COG2205	protein histidine kinase activity
Asp14428_44250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Asp14428_44300	COG0784	Response regulator, receiver
Asp14428_44300	COG2205	protein histidine kinase activity
Asp14428_44320	COG2172	sigma factor antagonist activity
Asp14428_44330	COG1366	Belongs to the anti-sigma-factor antagonist family
Asp14428_44340	COG1366	Belongs to the anti-sigma-factor antagonist family
Asp14428_44360	COG1970	mechanosensitive ion channel activity
Asp14428_44520	COG2746	aminoglycoside 3-N-acetyltransferase activity
Asp14428_44550	COG3629	intracellular signal transduction
Asp14428_44550	COG3903	Transcriptional regulator
Asp14428_44600	COG0641	radical SAM
Asp14428_44670	COG0667	Aldo Keto reductase
Asp14428_44710	COG2161	toxin-antitoxin pair type II binding
Asp14428_44800	COG0308	aminopeptidase N
Asp14428_44930	COG4213	ABC transporter substrate-binding protein
Asp14428_44940	COG4249	Peptidase C14 caspase catalytic subunit p20
Asp14428_44940	COG2319	Wd-40 repeat
Asp14428_44990	COG2801	Transposase and inactivated derivatives
Asp14428_45070	COG0438	transferase activity, transferring glycosyl groups
Asp14428_45080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asp14428_45080	COG0438	transferase activity, transferring glycosyl groups
Asp14428_45100	COG0277	FAD linked oxidase domain protein
Asp14428_45110	COG0277	FAD linked oxidase domain protein
Asp14428_45160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asp14428_45210	COG0142	geranyltranstransferase activity
Asp14428_45230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Asp14428_45530	COG1051	belongs to the nudix hydrolase family
Asp14428_45550	COG0464	growth
Asp14428_45630	COG2050	protein possibly involved in aromatic compounds catabolism
Asp14428_45740	COG0641	radical SAM
Asp14428_45750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Asp14428_45790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Asp14428_45800	COG0047	phosphoribosylformylglycinamidine synthase activity
Asp14428_45810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Asp14428_45830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Asp14428_45870	COG0151	Belongs to the GarS family
Asp14428_45880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Asp14428_45990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Asp14428_46000	COG0586	Pfam SNARE associated Golgi protein
Asp14428_46020	COG0640	Transcriptional regulator
Asp14428_46070	COG0542	response to heat
Asp14428_46080	COG2814	Major facilitator Superfamily
Asp14428_46120	COG0789	Transcriptional regulator
Asp14428_46130	COG0484	heat shock protein binding
Asp14428_46140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Asp14428_46150	COG0443	Heat shock 70 kDa protein
Asp14428_46230	COG0022	dehydrogenase e1 component
Asp14428_46240	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asp14428_46290	COG1733	regulation of RNA biosynthetic process
Asp14428_46300	COG0702	epimerase
Asp14428_46330	COG1960	acyl-CoA dehydrogenase activity
Asp14428_46400	COG0717	Belongs to the dCTP deaminase family
Asp14428_46450	COG1609	Transcriptional regulator
Asp14428_46530	COG0247	lactate metabolic process
Asp14428_46530	COG2181	nitrate reductase activity
Asp14428_46600	COG0515	serine threonine protein kinase
Asp14428_46600	COG2815	serine threonine protein kinase
Asp14428_46610	COG0515	serine threonine protein kinase
Asp14428_46620	COG0768	penicillin binding
Asp14428_46650	COG1716	ATPase activity
Asp14428_46660	COG1716	ATPase activity
Asp14428_46660	COG1716	ATPase activity
Asp14428_46680	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Asp14428_46770	COG2353	YceI-like domain
Asp14428_46800	COG1960	acyl-CoA dehydrogenase activity
Asp14428_46810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Asp14428_46840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asp14428_46850	COG0439	Biotin carboxylase
Asp14428_46900	COG0442	prolyl-tRNA aminoacylation
Asp14428_46930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asp14428_46990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Asp14428_47050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Asp14428_47060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Asp14428_47070	COG0187	DNA topoisomerase II activity
Asp14428_47090	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Asp14428_47100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Asp14428_47110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Asp14428_47120	COG0592	DNA-directed DNA polymerase activity
Asp14428_47150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Asp14428_47160	COG0594	ribonuclease P activity
Asp14428_47170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Asp14428_47180	COG0706	membrane insertase activity
Asp14428_47200	COG0357	Ribosomal RNA small subunit methyltransferase G
Asp14428_47210	COG1192	Involved in chromosome partitioning
Asp14428_47270	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asp14428_47280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asp14428_47310	COG3409	Peptidoglycan-binding domain 1 protein
Asp14428_47310	COG0860	N-Acetylmuramoyl-L-alanine amidase
Asp14428_47320	COG3118	belongs to the thioredoxin family
Asp14428_47330	COG0492	ferredoxin-NADP+ reductase activity
Asp14428_47350	COG1595	DNA-templated transcription, initiation
Asp14428_47360	COG2815	serine threonine protein kinase
Asp14428_47360	COG0515	serine threonine protein kinase
Asp14428_47390	COG0617	tRNA 3'-terminal CCA addition
Asp14428_47420	COG1260	myo-inositol-1-phosphate synthase
Asp14428_47430	COG1695	Transcriptional regulator
Asp14428_47450	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Asp14428_47510	COG0360	Binds together with S18 to 16S ribosomal RNA
Asp14428_47530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Asp14428_47540	COG0359	binds to the 23S rRNA
Asp14428_47670	COG0315	cyclic pyranopterin monophosphate synthase activity
Asp14428_47680	COG0521	Mo-molybdopterin cofactor biosynthetic process
Asp14428_47680	COG0315	cyclic pyranopterin monophosphate synthase activity
Asp14428_47780	COG1408	metallophosphoesterase
Asp14428_47800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Asp14428_47850	COG3540	Alkaline phosphatase
Asp14428_47860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Asp14428_47870	COG0746	molybdenum cofactor guanylyltransferase activity
Asp14428_47920	COG1834	amidinotransferase
Asp14428_47940	COG0561	phosphatase activity
Asp14428_47950	COG0561	phosphatase activity
Asp14428_47960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Asp14428_47980	COG1764	response to oxidative stress
Asp14428_48100	COG5002	protein histidine kinase activity
Asp14428_48160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Asp14428_48190	COG0180	Tryptophanyl-tRNA synthetase
Asp14428_48240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Asp14428_48270	COG2205	protein histidine kinase activity
Asp14428_48280	COG0745	RESPONSE REGULATOR receiver
Asp14428_48300	COG3275	phosphorelay sensor kinase activity
Asp14428_48310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asp14428_48320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asp14428_48330	COG0438	transferase activity, transferring glycosyl groups
Asp14428_48370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asp14428_48380	COG0598	Magnesium transport protein CorA
Asp14428_48410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Asp14428_48440	COG0183	Belongs to the thiolase family
Asp14428_48460	COG3958	Transketolase
Asp14428_48470	COG3959	Transketolase, thiamine diphosphate binding domain
Asp14428_48480	COG0789	Transcriptional regulator
Asp14428_48530	COG0243	molybdopterin cofactor binding
Asp14428_48570	COG1309	transcriptional regulator
Asp14428_48850	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_48850	COG3321	synthase
Asp14428_48850	COG0604	alcohol dehydrogenase
Asp14428_48870	COG0789	Transcriptional regulator
Asp14428_48930	COG1881	PFAM PEBP family protein
Asp14428_49000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Asp14428_49100	COG2226	methyltransferase
Asp14428_49100	COG1073	alpha beta
Asp14428_49120	COG2124	cytochrome p450
Asp14428_49140	COG2124	cytochrome p450
Asp14428_49150	COG5285	phytanoyl-CoA dioxygenase
Asp14428_49170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_49190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Asp14428_49210	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Asp14428_49220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asp14428_49250	COG0477	Major facilitator Superfamily
Asp14428_49280	COG0640	Transcriptional regulator
Asp14428_49310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Asp14428_49360	COG5001	Diguanylate cyclase
Asp14428_49370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Asp14428_49390	COG0701	Predicted permease
Asp14428_49400	COG0640	Transcriptional regulator
Asp14428_49420	COG0179	Fumarylacetoacetate (FAA) hydrolase
Asp14428_49550	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Asp14428_49650	COG0745	RESPONSE REGULATOR receiver
Asp14428_49660	COG2205	protein histidine kinase activity
Asp14428_49720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Asp14428_49950	COG3979	chitinase
Asp14428_50010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Asp14428_50020	COG1215	transferase activity, transferring glycosyl groups
Asp14428_50100	COG2018	Roadblock/LC7 domain
Asp14428_50110	COG0642	Histidine kinase
Asp14428_50130	COG3547	Transposase (IS116 IS110 IS902 family)
Asp14428_50140	COG0501	Belongs to the peptidase M48B family
Asp14428_50150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Asp14428_50150	COG1796	DNA polymerase
Asp14428_50170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Asp14428_50170	COG0235	Class ii aldolase
Asp14428_50220	COG0287	Prephenate dehydrogenase
Asp14428_50230	COG2318	DinB family
Asp14428_50260	COG0813	purine-nucleoside phosphorylase activity
Asp14428_50300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Asp14428_50420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Asp14428_50430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Asp14428_50440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asp14428_50450	COG0747	negative chemotaxis
Asp14428_50480	COG4608	Belongs to the ABC transporter superfamily
Asp14428_50520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asp14428_50590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Asp14428_50610	COG0789	Transcriptional regulator
Asp14428_50620	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_50630	COG2205	protein histidine kinase activity
Asp14428_50640	COG0745	RESPONSE REGULATOR receiver
Asp14428_50650	COG2409	Drug exporters of the RND superfamily
Asp14428_50700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Asp14428_50720	COG0003	Pfam Anion-transporting ATPase
Asp14428_50760	COG0251	oxidation-reduction process
Asp14428_50770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asp14428_50820	COG0825	malonyl-CoA metabolic process
Asp14428_50850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Asp14428_50860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asp14428_50900	COG1674	ftsk spoiiie
Asp14428_50920	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Asp14428_50940	COG2027	D-alanyl-D-alanine carboxypeptidase
Asp14428_50960	COG0037	tRNA processing
Asp14428_50970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Asp14428_50980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asp14428_50990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asp14428_51000	COG0302	gtp cyclohydrolase
Asp14428_51040	COG1674	ftsk spoiiie
Asp14428_51060	COG0739	heme binding
Asp14428_51130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Asp14428_51140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Asp14428_51210	COG0517	IMP dehydrogenase activity
Asp14428_51210	COG1125	glycine betaine transport
Asp14428_51220	COG1174	glycine betaine transport
Asp14428_51230	COG1174	glycine betaine transport
Asp14428_51260	COG0649	NAD binding
Asp14428_51290	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Asp14428_51300	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Asp14428_51320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Asp14428_51340	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Asp14428_51410	COG1194	a g-specific adenine glycosylase
Asp14428_51420	COG3830	Belongs to the UPF0237 family
Asp14428_51430	COG0242	peptide deformylase activity
Asp14428_51450	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Asp14428_51460	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Asp14428_51490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asp14428_51500	COG1960	acyl-CoA dehydrogenase activity
Asp14428_51550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Asp14428_51560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Asp14428_51590	COG1486	melibiose metabolic process
Asp14428_51600	COG0395	ABC-type sugar transport system, permease component
Asp14428_51630	COG1846	Transcriptional regulator
Asp14428_51630	COG1940	carbohydrate kinase activity
Asp14428_51710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asp14428_51740	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Asp14428_51770	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Asp14428_51770	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Asp14428_51780	COG3177	Filamentation induced by cAMP protein fic
Asp14428_51810	COG0114	fumarate hydratase activity
Asp14428_51830	COG0215	cysteine-tRNA ligase activity
Asp14428_51840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Asp14428_51850	COG0443	Heat shock 70 kDa protein
Asp14428_51860	COG3842	ATPase activity
Asp14428_51900	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Asp14428_51950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Asp14428_51980	COG1349	DNA-binding transcription factor activity
Asp14428_52000	COG1131	(ABC) transporter
Asp14428_52020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asp14428_52050	COG1131	(ABC) transporter
Asp14428_52060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Asp14428_52090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Asp14428_52100	COG0459	protein refolding
Asp14428_52110	COG0456	acetyltransferase
Asp14428_52170	COG4129	membrane
Asp14428_52190	COG2339	peptidase activity
Asp14428_52230	COG1595	DNA-templated transcription, initiation
Asp14428_52260	COG0306	phosphate transporter
Asp14428_52280	COG0673	inositol 2-dehydrogenase activity
Asp14428_52300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Asp14428_52310	COG0581	inorganic phosphate transmembrane transporter activity
Asp14428_52340	COG0456	acetyltransferase
Asp14428_52350	COG0745	RESPONSE REGULATOR receiver
Asp14428_52440	COG4044	May play a role in the intracellular transport of hydrophobic ligands
Asp14428_52490	COG3246	L-lysine catabolic process to acetate
Asp14428_52610	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Asp14428_52630	COG5002	protein histidine kinase activity
Asp14428_52640	COG0745	RESPONSE REGULATOR receiver
Asp14428_52650	COG0643	Histidine kinase
Asp14428_52650	COG0784	Response regulator, receiver
Asp14428_52650	COG2198	Histidine kinase
Asp14428_52660	COG0835	chemotaxis
Asp14428_52680	COG2201	protein-glutamate methylesterase activity
Asp14428_52690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Asp14428_52700	COG0745	RESPONSE REGULATOR receiver
Asp14428_52720	COG0745	RESPONSE REGULATOR receiver
Asp14428_52770	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Asp14428_52800	COG1338	Plays a role in the flagellum-specific transport system
Asp14428_52820	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Asp14428_52820	COG1776	CheC inhibitor of MCP methylation
Asp14428_52830	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Asp14428_52840	COG1580	Controls the rotational direction of flagella during chemotaxis
Asp14428_52860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Asp14428_52890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Asp14428_52910	COG0741	lytic transglycosylase activity
Asp14428_52930	COG1157	protein secretion by the type III secretion system
Asp14428_52950	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Asp14428_52960	COG1766	The M ring may be actively involved in energy transduction
Asp14428_52970	COG1677	Flagellar hook-basal body complex protein FliE
Asp14428_53000	COG1516	flagellar protein fliS
Asp14428_53010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Asp14428_53040	COG1256	bacterial-type flagellum assembly
Asp14428_53040	COG4786	Flagellar basal body rod
Asp14428_53050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Asp14428_53060	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Asp14428_53070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Asp14428_53110	COG2205	protein histidine kinase activity
Asp14428_53140	COG0745	RESPONSE REGULATOR receiver
Asp14428_53180	COG0438	transferase activity, transferring glycosyl groups
Asp14428_53210	COG1191	sigma factor activity
Asp14428_53240	COG0588	phosphoglycerate mutase activity
Asp14428_53290	COG1082	Xylose isomerase domain protein TIM barrel
Asp14428_53310	COG0506	proline dehydrogenase activity
Asp14428_53360	COG1595	DNA-templated transcription, initiation
Asp14428_53370	COG0318	PFAM AMP-dependent synthetase and ligase
Asp14428_53400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Asp14428_53410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Asp14428_53420	COG0181	hydroxymethylbilane synthase activity
Asp14428_53430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Asp14428_53430	COG1648	precorrin-2 dehydrogenase activity
Asp14428_53440	COG0113	porphobilinogen synthase activity
Asp14428_53510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Asp14428_53520	COG1013	pyruvate-flavodoxin oxidoreductase activity
Asp14428_53530	COG0674	pyruvate-flavodoxin oxidoreductase activity
Asp14428_53530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Asp14428_53540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asp14428_53570	COG0519	Catalyzes the synthesis of GMP from XMP
Asp14428_53600	COG1024	Enoyl-CoA hydratase
Asp14428_53630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Asp14428_53650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asp14428_53660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asp14428_53700	COG2239	Acts as a magnesium transporter
Asp14428_53710	COG0384	phenazine biosynthesis protein PhzF
Asp14428_53780	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_53800	COG1832	CoA-binding protein
Asp14428_53820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asp14428_53870	COG0613	PHP domain protein
Asp14428_53880	COG2095	MarC family integral membrane protein
Asp14428_53990	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Asp14428_54010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Asp14428_54020	COG0303	'Molybdopterin
Asp14428_54060	COG4213	ABC transporter substrate-binding protein
Asp14428_54090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Asp14428_54110	COG0784	Response regulator, receiver
Asp14428_54110	COG2205	protein histidine kinase activity
Asp14428_54110	COG5002	protein histidine kinase activity
Asp14428_54170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asp14428_54200	COG0084	hydrolase, TatD family'
Asp14428_54220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Asp14428_54230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Asp14428_54240	COG0488	(ABC) transporter
Asp14428_54260	COG1309	transcriptional regulator
Asp14428_54300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Asp14428_54390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Asp14428_54410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Asp14428_54420	COG0193	aminoacyl-tRNA hydrolase activity
Asp14428_54430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asp14428_54440	COG1218	3'(2'),5'-bisphosphate nucleotidase
Asp14428_54470	COG1609	Transcriptional regulator
Asp14428_54500	COG1175	transmembrane transport
Asp14428_54510	COG0395	ABC-type sugar transport system, permease component
Asp14428_54520	COG3507	Belongs to the glycosyl hydrolase 43 family
Asp14428_54550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Asp14428_54570	COG0180	Tryptophanyl-tRNA synthetase
Asp14428_54620	COG1744	ABC transporter substrate-binding protein PnrA-like
Asp14428_54630	COG3845	ABC transporter
Asp14428_54640	COG4603	Belongs to the binding-protein-dependent transport system permease family
Asp14428_54650	COG1079	Belongs to the binding-protein-dependent transport system permease family
Asp14428_54660	COG1079	Belongs to the binding-protein-dependent transport system permease family
Asp14428_54710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asp14428_54720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asp14428_54740	COG2018	Roadblock/LC7 domain
Asp14428_54750	COG2018	Roadblock/LC7 domain
Asp14428_54800	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_54810	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_54820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Asp14428_54830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Asp14428_54840	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Asp14428_54870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asp14428_54880	COG0515	serine threonine protein kinase
Asp14428_54880	COG2815	serine threonine protein kinase
Asp14428_54890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asp14428_54890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asp14428_54900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asp14428_54900	COG1473	amidohydrolase
Asp14428_55000	COG4770	biotin carboxylase activity
Asp14428_55040	COG0424	maF-like protein
Asp14428_55050	COG1404	Belongs to the peptidase S8 family
Asp14428_55080	COG2815	serine threonine protein kinase
Asp14428_55080	COG0515	serine threonine protein kinase
Asp14428_55120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Asp14428_55210	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Asp14428_55240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Asp14428_55270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asp14428_55270	COG1877	trehalose-phosphatase activity
Asp14428_55280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Asp14428_55330	COG0705	Rhomboid family
Asp14428_55380	COG1722	exodeoxyribonuclease VII activity
Asp14428_55390	COG1570	exodeoxyribonuclease VII activity
Asp14428_55420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Asp14428_55440	COG1322	Protein conserved in bacteria
Asp14428_55470	COG0525	valine-tRNA ligase activity
Asp14428_55510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Asp14428_55580	COG0012	GTP binding
Asp14428_55640	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_55650	COG0300	oxidoreductase activity
Asp14428_55660	COG1309	transcriptional regulator
Asp14428_55840	COG0318	PFAM AMP-dependent synthetase and ligase
Asp14428_55850	COG1960	acyl-CoA dehydrogenase activity
Asp14428_55930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Asp14428_55940	COG0121	glutamine amidotransferase
Asp14428_55950	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Asp14428_55980	COG1960	acyl-CoA dehydrogenase activity
Asp14428_56100	COG1053	succinate dehydrogenase
Asp14428_56230	COG0583	DNA-binding transcription factor activity
Asp14428_56260	COG0823	Involved in the tonB-independent uptake of proteins
Asp14428_56260	COG1506	peptidase
Asp14428_56270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asp14428_56310	COG1760	l-serine dehydratase
Asp14428_56370	COG1404	Belongs to the peptidase S8 family
Asp14428_56400	COG1597	lipid kinase activity
Asp14428_56410	COG4213	ABC transporter substrate-binding protein
Asp14428_56430	COG4214	carbohydrate transport
Asp14428_56670	COG4221	oxidoreductase activity
Asp14428_56680	COG1619	proteins homologs of microcin C7 resistance protein MccF
Asp14428_56700	COG0489	protein tyrosine kinase activity
Asp14428_56720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asp14428_56730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asp14428_56820	COG3226	Transcriptional regulator
Asp14428_56890	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Asp14428_56940	COG2826	transposase and inactivated derivatives, IS30 family
Asp14428_57030	COG0297	glycogen (starch) synthase activity
Asp14428_57070	COG1086	Polysaccharide biosynthesis protein
Asp14428_57090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asp14428_57100	COG3629	intracellular signal transduction
Asp14428_57100	COG3903	Transcriptional regulator
Asp14428_57170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Asp14428_57190	COG2199	diguanylate cyclase activity
Asp14428_57190	COG2200	EAL domain
Asp14428_57200	COG2200	EAL domain
Asp14428_57240	COG4251	negative regulation of phosphorylation
Asp14428_57240	COG3706	GGDEF domain
Asp14428_57240	COG5001	Diguanylate cyclase
Asp14428_57240	COG2203	Gaf domain
Asp14428_57290	COG1335	isochorismatase
Asp14428_57320	COG0667	Aldo Keto reductase
Asp14428_57380	COG0156	8-amino-7-oxononanoate synthase activity
Asp14428_57390	COG5001	Diguanylate cyclase
Asp14428_57390	COG3300	MHYT domain
Asp14428_57470	COG1611	Belongs to the LOG family
Asp14428_57480	COG1611	Belongs to the LOG family
Asp14428_57500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asp14428_57510	COG2171	N-acyltransferase activity
Asp14428_57520	COG1609	Transcriptional regulator
Asp14428_57530	COG0210	DNA helicase
Asp14428_57570	COG1278	Cold shock
Asp14428_57620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Asp14428_57640	COG1959	2 iron, 2 sulfur cluster binding
Asp14428_57710	COG2816	NAD+ diphosphatase activity
Asp14428_57720	COG5285	phytanoyl-CoA dioxygenase
Asp14428_57790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Asp14428_57860	COG3480	Lon protease (S16) C-terminal proteolytic domain
Asp14428_57870	COG1615	UPF0182 protein
Asp14428_57880	COG1615	UPF0182 protein
Asp14428_57950	COG1357	PFAM Pentapeptide repeats (8 copies)
Asp14428_57980	COG2409	Drug exporters of the RND superfamily
Asp14428_58140	COG2197	response regulator
Asp14428_58180	COG0483	inositol monophosphate 1-phosphatase activity
Asp14428_58190	COG1162	GTPase activity
Asp14428_58200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Asp14428_58210	COG2135	peptidase activity
Asp14428_58240	COG1595	DNA-templated transcription, initiation
Asp14428_58250	COG5662	AntiSigma factor
Asp14428_58260	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Asp14428_58280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asp14428_58310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Asp14428_58330	COG0175	sulfate reduction
Asp14428_58360	COG1597	lipid kinase activity
Asp14428_58380	COG2188	Transcriptional regulator
Asp14428_58390	COG2172	sigma factor antagonist activity
Asp14428_58470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Asp14428_58480	COG0280	phosphate acetyltransferase
Asp14428_58480	COG0857	belongs to the CobB CobQ family
Asp14428_58520	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asp14428_58520	COG0567	Dehydrogenase, E1 component
Asp14428_58550	COG1131	(ABC) transporter
Asp14428_58590	COG0745	RESPONSE REGULATOR receiver
Asp14428_58600	COG2205	protein histidine kinase activity
Asp14428_58610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asp14428_58650	COG3842	ATPase activity
Asp14428_58670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asp14428_58700	COG0740	serine-type endopeptidase activity
Asp14428_58720	COG1834	amidinotransferase
Asp14428_58730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Asp14428_58750	COG2154	pterin-4-alpha-carbinolamine dehydratase
Asp14428_58800	COG0446	pyridine nucleotide-disulphide oxidoreductase
Asp14428_58810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asp14428_58850	COG3469	chitinase activity
Asp14428_58860	COG0586	Pfam SNARE associated Golgi protein
Asp14428_58910	COG0366	Alpha amylase catalytic
Asp14428_58940	COG0754	glutathionylspermidine amidase activity
Asp14428_58970	COG0673	inositol 2-dehydrogenase activity
Asp14428_59000	COG1595	DNA-templated transcription, initiation
Asp14428_59070	COG1742	UPF0060 membrane protein
Asp14428_59170	COG0644	oxidoreductase
Asp14428_59180	COG0515	serine threonine protein kinase
Asp14428_59180	COG2815	serine threonine protein kinase
Asp14428_59220	COG0300	oxidoreductase activity
Asp14428_59260	COG4249	Peptidase C14 caspase catalytic subunit p20
Asp14428_59260	COG2319	Wd-40 repeat
Asp14428_59360	COG0018	arginyl-trna synthetase
Asp14428_59370	COG0019	diaminopimelate decarboxylase activity
Asp14428_59380	COG0460	homoserine dehydrogenase
Asp14428_59390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Asp14428_59400	COG1846	Transcriptional regulator
Asp14428_59410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Asp14428_59440	COG0083	homoserine kinase activity
Asp14428_59460	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Asp14428_59510	COG0254	rRNA binding
Asp14428_59520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Asp14428_59530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Asp14428_59560	COG2890	protein-(glutamine-N5) methyltransferase activity
Asp14428_59580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Asp14428_59590	COG0009	L-threonylcarbamoyladenylate synthase
Asp14428_59600	COG0702	epimerase
Asp14428_59610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Asp14428_59640	COG0356	it plays a direct role in the translocation of protons across the membrane
Asp14428_59650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Asp14428_59660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Asp14428_59670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Asp14428_59680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Asp14428_59690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Asp14428_59700	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Asp14428_59720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Asp14428_59780	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asp14428_59820	COG1674	ftsk spoiiie
Asp14428_59850	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Asp14428_59870	COG1116	anion transmembrane transporter activity
Asp14428_59940	COG0346	lactoylglutathione lyase activity
Asp14428_59950	COG0183	Belongs to the thiolase family
Asp14428_59960	COG1703	isobutyryl-CoA mutase activity
Asp14428_60000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asp14428_60000	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asp14428_60070	COG0768	penicillin binding
Asp14428_60080	COG2902	Dehydrogenase
Asp14428_60150	COG1119	ATPase activity
Asp14428_60160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asp14428_60180	COG0840	transmembrane signaling receptor activity
Asp14428_60260	COG2149	membrane
Asp14428_60290	COG0482	sulfurtransferase activity
Asp14428_60320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Asp14428_60340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Asp14428_60350	COG0154	amidase activity
Asp14428_60360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Asp14428_60390	COG2133	pyrroloquinoline quinone binding
Asp14428_60450	COG2203	Gaf domain
Asp14428_60450	COG3706	GGDEF domain
Asp14428_60450	COG4251	negative regulation of phosphorylation
Asp14428_60450	COG5001	Diguanylate cyclase
Asp14428_60490	COG1609	Transcriptional regulator
Asp14428_60500	COG1653	transport
Asp14428_60520	COG0395	ABC-type sugar transport system, permease component
Asp14428_60540	COG0657	acetylesterase activity
Asp14428_60550	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_60570	COG0129	dihydroxy-acid dehydratase activity
Asp14428_60580	COG5001	Diguanylate cyclase
Asp14428_60600	COG0440	acetolactate synthase activity
Asp14428_60660	COG0473	3-isopropylmalate dehydrogenase activity
Asp14428_60670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Asp14428_60690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asp14428_60770	COG0612	Peptidase, M16
Asp14428_60780	COG0714	Associated with various cellular activities
Asp14428_60790	COG2304	oxidoreductase activity
Asp14428_60800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asp14428_60810	COG0745	RESPONSE REGULATOR receiver
Asp14428_60820	COG2205	protein histidine kinase activity
Asp14428_60850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Asp14428_60910	COG3842	ATPase activity
Asp14428_60920	COG1177	transmembrane transport
Asp14428_60930	COG1176	ABC-type spermidine putrescine transport system, permease component I
Asp14428_60950	COG3246	L-lysine catabolic process to acetate
Asp14428_60980	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_60990	COG1454	alcohol dehydrogenase
Asp14428_61040	COG1131	(ABC) transporter
Asp14428_61060	COG1476	TRANSCRIPTIONal
Asp14428_61090	COG0702	epimerase
Asp14428_61130	COG0066	3-isopropylmalate dehydratase activity
Asp14428_61140	COG0776	regulation of translation
Asp14428_61160	COG0406	alpha-ribazole phosphatase activity
Asp14428_61160	COG0494	nUDIX hydrolase
Asp14428_61170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Asp14428_61190	COG1920	GTP binding
Asp14428_61220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Asp14428_61230	COG0626	cystathionine gamma-synthase activity
Asp14428_61250	COG2188	Transcriptional regulator
Asp14428_61260	COG1131	(ABC) transporter
Asp14428_61290	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asp14428_61340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Asp14428_61350	COG1461	Dihydroxyacetone kinase
Asp14428_61370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Asp14428_61430	COG0742	ribosomal rna small subunit methyltransferase
Asp14428_61440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Asp14428_61470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Asp14428_61480	COG0416	fatty acid biosynthetic process
Asp14428_61490	COG0571	ribonuclease III activity
Asp14428_61520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asp14428_61550	COG2340	Cysteine-rich secretory protein family
Asp14428_61600	COG2318	DinB family
Asp14428_61680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Asp14428_61690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Asp14428_61700	COG0463	Glycosyl transferase, family 2
Asp14428_61740	COG2755	lipolytic protein G-D-S-L family
Asp14428_61740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Asp14428_61760	COG0438	transferase activity, transferring glycosyl groups
Asp14428_61810	COG0442	prolyl-tRNA aminoacylation
Asp14428_61840	COG0228	four-way junction DNA binding
Asp14428_61850	COG1837	Belongs to the UPF0109 family
Asp14428_61860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Asp14428_61870	COG0336	Belongs to the RNA methyltransferase TrmD family
Asp14428_61880	COG0336	Belongs to the RNA methyltransferase TrmD family
Asp14428_61890	COG0335	large ribosomal subunit rRNA binding
Asp14428_61900	COG0681	Belongs to the peptidase S26 family
Asp14428_61910	COG0681	Belongs to the peptidase S26 family
Asp14428_61930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Asp14428_61960	COG2207	Transcriptional regulator
Asp14428_61960	COG3708	Transcriptional regulator
Asp14428_61970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asp14428_62020	COG2188	Transcriptional regulator
Asp14428_62080	COG0792	nuclease activity
Asp14428_62100	COG0052	Belongs to the universal ribosomal protein uS2 family
Asp14428_62110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Asp14428_62120	COG0528	UMP kinase activity
Asp14428_62130	COG0233	cytoplasmic translational termination
Asp14428_62150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Asp14428_62180	COG2146	nitrite reductase [NAD(P)H] activity
Asp14428_62180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Asp14428_62210	COG2409	Drug exporters of the RND superfamily
Asp14428_62280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Asp14428_62330	COG1511	domain protein
Asp14428_62340	COG1309	transcriptional regulator
Asp14428_62410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Asp14428_62460	COG1012	belongs to the aldehyde dehydrogenase family
Asp14428_62490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Asp14428_62500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Asp14428_62590	COG0779	Required for maturation of 30S ribosomal subunits
Asp14428_62600	COG0195	Participates in both transcription termination and antitermination
Asp14428_62610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Asp14428_62640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Asp14428_62650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Asp14428_62680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Asp14428_62690	COG0745	RESPONSE REGULATOR receiver
Asp14428_62700	COG2205	protein histidine kinase activity
Asp14428_62700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asp14428_62720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Asp14428_62730	COG1185	polyribonucleotide nucleotidyltransferase activity
Asp14428_62740	COG0612	Peptidase, M16
Asp14428_62760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Asp14428_62790	COG3214	Protein conserved in bacteria
Asp14428_62810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asp14428_62820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Asp14428_62860	COG1674	ftsk spoiiie
Asp14428_62870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asp14428_62910	COG1546	Belongs to the CinA family
Asp14428_62910	COG1058	Belongs to the CinA family
Asp14428_62920	COG1396	sequence-specific DNA binding
Asp14428_62930	COG1842	Phage shock protein A
Asp14428_62950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asp14428_62970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_63000	COG1201	RNA secondary structure unwinding
Asp14428_63030	COG2815	serine threonine protein kinase
Asp14428_63030	COG0515	serine threonine protein kinase
Asp14428_63060	COG1253	flavin adenine dinucleotide binding
Asp14428_63070	COG4326	sporulation control protein
Asp14428_63110	COG1573	uracil-dna glycosylase
Asp14428_63130	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Asp14428_63140	COG2137	regulation of response to DNA damage stimulus
Asp14428_63180	COG1418	mRNA catabolic process
Asp14428_63190	COG0765	amino acid transport
Asp14428_63200	COG0765	amino acid transport
Asp14428_63210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asp14428_63220	COG1126	abc transporter atp-binding protein
Asp14428_63240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asp14428_63270	COG1196	nuclear chromosome segregation
Asp14428_63280	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Asp14428_63290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Asp14428_63300	COG0584	glycerophosphoryl diester phosphodiesterase
Asp14428_63320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Asp14428_63340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Asp14428_63370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Asp14428_63380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Asp14428_63390	COG0738	Major facilitator superfamily
Asp14428_63500	COG1490	D-aminoacyl-tRNA deacylase activity
Asp14428_63610	COG2313	pseudouridylate synthase activity
Asp14428_63630	COG2860	membrane
Asp14428_63680	COG0483	inositol monophosphate 1-phosphatase activity
Asp14428_63730	COG0756	dUTP diphosphatase activity
Asp14428_63780	COG0569	domain protein
Asp14428_63790	COG0531	amino acid
Asp14428_63800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Asp14428_63810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Asp14428_63850	COG0745	RESPONSE REGULATOR receiver
Asp14428_63860	COG2205	protein histidine kinase activity
Asp14428_63870	COG3547	Transposase (IS116 IS110 IS902 family)
Asp14428_63920	COG1024	Enoyl-CoA hydratase
Asp14428_63920	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asp14428_63930	COG0183	Belongs to the thiolase family
Asp14428_63960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Asp14428_63970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asp14428_63990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Asp14428_64000	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Asp14428_64010	COG3253	May function as heme-dependent peroxidase
Asp14428_64040	COG0655	NAD(P)H dehydrogenase (quinone) activity
Asp14428_64070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Asp14428_64100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asp14428_64150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asp14428_64170	COG1793	dna ligase
Asp14428_64180	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_64210	COG1131	(ABC) transporter
Asp14428_64270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Asp14428_64320	COG1597	lipid kinase activity
Asp14428_64340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asp14428_64350	COG1554	hydrolase, family 65, central catalytic
Asp14428_64360	COG1253	flavin adenine dinucleotide binding
Asp14428_64370	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Asp14428_64380	COG0156	8-amino-7-oxononanoate synthase activity
Asp14428_64390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Asp14428_64430	COG3547	Transposase (IS116 IS110 IS902 family)
Asp14428_64470	COG0420	3'-5' exonuclease activity
Asp14428_64480	COG0419	ATPase involved in DNA repair
Asp14428_64580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asp14428_64610	COG2264	protein methyltransferase activity
Asp14428_64620	COG1914	H( )-stimulated, divalent metal cation uptake system
Asp14428_64630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Asp14428_64640	COG4336	lyase activity
Asp14428_64650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Asp14428_64660	COG1984	allophanate hydrolase subunit 2
Asp14428_64670	COG2188	Transcriptional regulator
Asp14428_64750	COG2197	response regulator
Asp14428_64770	COG1609	Transcriptional regulator
Asp14428_64810	COG4821	SIS domain
Asp14428_64830	COG1175	transmembrane transport
Asp14428_64840	COG0395	ABC-type sugar transport system, permease component
Asp14428_64850	COG0395	ABC-type sugar transport system, permease component
Asp14428_64870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asp14428_64950	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_64970	COG4585	Histidine kinase
Asp14428_64980	COG2197	response regulator
Asp14428_65000	COG5001	Diguanylate cyclase
Asp14428_65020	COG1404	Belongs to the peptidase S8 family
Asp14428_65080	COG2409	Drug exporters of the RND superfamily
Asp14428_65200	COG2357	RelA SpoT domain protein
Asp14428_65230	COG3903	Transcriptional regulator
Asp14428_65230	COG3629	intracellular signal transduction
Asp14428_65270	COG3250	beta-galactosidase activity
Asp14428_65300	COG2197	response regulator
Asp14428_65310	COG4585	Histidine kinase
Asp14428_65320	COG3693	PFAM glycoside hydrolase, family 10
Asp14428_65330	COG3693	PFAM glycoside hydrolase, family 10
Asp14428_65560	COG1674	ftsk spoiiie
Asp14428_65720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asp14428_65730	COG0823	Involved in the tonB-independent uptake of proteins
Asp14428_65870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Asp14428_65950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_66070	COG1309	transcriptional regulator
Asp14428_66130	COG3537	Alpha-1,2-mannosidase
Asp14428_66160	COG3321	synthase
Asp14428_66160	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_66160	COG0604	alcohol dehydrogenase
Asp14428_66170	COG1309	transcriptional regulator
Asp14428_66200	COG1609	Transcriptional regulator
Asp14428_66210	COG0395	ABC-type sugar transport system, permease component
Asp14428_66220	COG1175	transmembrane transport
Asp14428_66230	COG1175	transmembrane transport
Asp14428_66240	COG1653	transport
Asp14428_66300	COG3467	pyridoxamine 5'-phosphate
Asp14428_66340	COG1609	Transcriptional regulator
Asp14428_66380	COG0328	RNA-DNA hybrid ribonuclease activity
Asp14428_66480	COG1215	transferase activity, transferring glycosyl groups
Asp14428_66620	COG0277	FAD linked oxidase domain protein
Asp14428_66650	COG1136	(ABC) transporter
Asp14428_66690	COG3903	Transcriptional regulator
Asp14428_66690	COG3629	intracellular signal transduction
Asp14428_66740	COG1846	Transcriptional regulator
Asp14428_66770	COG3250	beta-galactosidase activity
Asp14428_66800	COG0725	ABC transporter, periplasmic molybdate-binding protein
Asp14428_66920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_66930	COG1116	anion transmembrane transporter activity
Asp14428_66990	COG0183	Belongs to the thiolase family
Asp14428_67010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Asp14428_67040	COG2814	Major facilitator Superfamily
Asp14428_67070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Asp14428_67160	COG1506	peptidase
Asp14428_67160	COG4946	Tricorn protease homolog
Asp14428_67160	COG0823	Involved in the tonB-independent uptake of proteins
Asp14428_67170	COG0367	asparagine synthase
Asp14428_67180	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asp14428_67180	COG2308	Evidence 4 Homologs of previously reported genes of
Asp14428_67190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asp14428_67190	COG0574	Belongs to the PEP-utilizing enzyme family
Asp14428_67210	COG0659	secondary active sulfate transmembrane transporter activity
Asp14428_67360	COG0366	Alpha amylase catalytic
Asp14428_67370	COG0395	ABC-type sugar transport system, permease component
Asp14428_67380	COG1175	transmembrane transport
Asp14428_67410	COG0840	transmembrane signaling receptor activity
Asp14428_67420	COG0789	Transcriptional regulator
Asp14428_67430	COG3012	SEC-C Motif Domain Protein
Asp14428_67440	COG3483	tryptophan 2,3-dioxygenase activity
Asp14428_67480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asp14428_67490	COG0673	inositol 2-dehydrogenase activity
Asp14428_67500	COG2226	methyltransferase
Asp14428_67540	COG0438	transferase activity, transferring glycosyl groups
Asp14428_67560	COG0438	transferase activity, transferring glycosyl groups
Asp14428_67570	COG0366	Alpha amylase catalytic
Asp14428_67600	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Asp14428_67700	COG3300	MHYT domain
Asp14428_67700	COG5001	Diguanylate cyclase
Asp14428_67720	COG0800	Aldolase
Asp14428_67800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asp14428_67850	COG0546	phosphoglycolate phosphatase activity
Asp14428_67910	COG0531	amino acid
Asp14428_67980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_68010	COG1960	acyl-CoA dehydrogenase activity
Asp14428_68020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_68040	COG1116	anion transmembrane transporter activity
Asp14428_68070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_68130	COG2124	cytochrome p450
Asp14428_68230	COG1803	Methylglyoxal synthase
Asp14428_68230	COG1597	lipid kinase activity
Asp14428_68250	COG0671	phosphoesterase, PA-phosphatase related
Asp14428_68270	COG1725	Transcriptional regulator
Asp14428_68280	COG1131	(ABC) transporter
Asp14428_68300	COG0745	RESPONSE REGULATOR receiver
Asp14428_68320	COG2409	Drug exporters of the RND superfamily
Asp14428_68440	COG0583	DNA-binding transcription factor activity
Asp14428_68450	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Asp14428_68510	COG2197	response regulator
Asp14428_68540	COG4585	Histidine kinase
Asp14428_68550	COG4585	Histidine kinase
Asp14428_68560	COG2197	response regulator
Asp14428_68690	COG4585	Histidine kinase
Asp14428_68700	COG2197	response regulator
Asp14428_68760	COG1131	(ABC) transporter
Asp14428_68880	COG0789	Transcriptional regulator
Asp14428_68890	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_68900	COG3321	synthase
Asp14428_68900	COG0604	alcohol dehydrogenase
Asp14428_68900	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_68910	COG1131	(ABC) transporter
Asp14428_69030	COG0739	heme binding
Asp14428_69060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Asp14428_69100	COG0598	Magnesium transport protein CorA
Asp14428_69110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Asp14428_69140	COG1309	transcriptional regulator
Asp14428_69160	COG0515	serine threonine protein kinase
Asp14428_69180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Asp14428_69190	COG2755	lipolytic protein G-D-S-L family
Asp14428_69220	COG0633	Ferredoxin
Asp14428_69220	COG0543	2 iron, 2 sulfur cluster binding
Asp14428_69230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asp14428_69290	COG1051	belongs to the nudix hydrolase family
Asp14428_69330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Asp14428_69360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asp14428_69370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asp14428_69380	COG1120	ATPase activity
Asp14428_69430	COG3552	Protein containing von Willebrand factor type A (VWA) domain
Asp14428_69450	COG0714	Associated with various cellular activities
Asp14428_69480	COG0697	spore germination
Asp14428_69520	COG0435	Glutathione S-transferase
Asp14428_69530	COG0387	Pfam Sodium calcium exchanger
Asp14428_69610	COG0745	RESPONSE REGULATOR receiver
Asp14428_69620	COG2205	protein histidine kinase activity
Asp14428_69650	COG2197	response regulator
Asp14428_69690	COG0187	DNA topoisomerase II activity
Asp14428_69760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asp14428_69770	COG1940	carbohydrate kinase activity
Asp14428_69780	COG2723	6-phospho-beta-galactosidase activity
Asp14428_69790	COG0444	Belongs to the ABC transporter superfamily
Asp14428_69800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asp14428_69810	COG0601	transmembrane transport
Asp14428_69840	COG1609	Transcriptional regulator
Asp14428_69850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Asp14428_69920	COG0513	Belongs to the DEAD box helicase family
Asp14428_69930	COG1191	sigma factor activity
Asp14428_69950	COG3973	AAA domain
Asp14428_69960	COG1191	sigma factor activity
Asp14428_69970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asp14428_69990	COG1686	Belongs to the peptidase S11 family
Asp14428_70010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_70060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_70070	COG1216	Glycosyl transferase, family 2
Asp14428_70080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_70090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asp14428_70100	COG1082	Xylose isomerase domain protein TIM barrel
Asp14428_70110	COG2936	dipeptidyl-peptidase activity
Asp14428_70180	COG0405	Gamma-glutamyltransferase
Asp14428_70230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Asp14428_70270	COG1247	-acetyltransferase
Asp14428_70300	COG0840	transmembrane signaling receptor activity
Asp14428_70400	COG1216	Glycosyl transferase, family 2
Asp14428_70410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asp14428_70480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Asp14428_70530	COG0840	transmembrane signaling receptor activity
Asp14428_70540	COG1643	Atp-dependent helicase
Asp14428_70550	COG1643	Atp-dependent helicase
Asp14428_70620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Asp14428_70640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asp14428_70650	COG4266	Belongs to the allantoicase family
Asp14428_70670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Asp14428_70750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asp14428_70790	COG0542	response to heat
Asp14428_70830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asp14428_70930	COG1295	ribonuclease BN
Asp14428_70990	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_71010	COG0438	transferase activity, transferring glycosyl groups
Asp14428_71040	COG4585	Histidine kinase
Asp14428_71050	COG2197	response regulator
Asp14428_71060	COG0514	ATP-dependent DNA helicase (RecQ)
Asp14428_71070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_71090	COG1472	Belongs to the glycosyl hydrolase 3 family
Asp14428_71160	COG1278	Cold shock
Asp14428_71190	COG0667	Aldo Keto reductase
Asp14428_71200	COG4106	trans-aconitate 2-methyltransferase activity
Asp14428_71220	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asp14428_71310	COG5001	Diguanylate cyclase
Asp14428_71340	COG1560	Kdo2-lipid A biosynthetic process
Asp14428_71350	COG0438	transferase activity, transferring glycosyl groups
Asp14428_71370	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Asp14428_71380	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Asp14428_71390	COG0217	transcriptional regulatory protein
Asp14428_71410	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Asp14428_71420	COG0632	four-way junction helicase activity
Asp14428_71430	COG2255	four-way junction helicase activity
Asp14428_71480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Asp14428_71490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asp14428_71500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Asp14428_71530	COG0124	histidyl-tRNA synthetase
Asp14428_71560	COG4242	Belongs to the peptidase S51 family
Asp14428_71570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Asp14428_71570	COG0189	ligase activity
Asp14428_71580	COG0515	serine threonine protein kinase
Asp14428_71620	COG0831	urea catabolic process
Asp14428_71630	COG0832	Belongs to the urease beta subunit family
Asp14428_71640	COG0804	urea catabolic process
Asp14428_71670	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Asp14428_71680	COG0829	nickel cation binding
Asp14428_71690	COG0251	oxidation-reduction process
Asp14428_71700	COG3964	amidohydrolase
Asp14428_71730	COG2268	Band 7 protein
Asp14428_71830	COG1175	transmembrane transport
Asp14428_71840	COG0395	ABC-type sugar transport system, permease component
Asp14428_71920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Asp14428_72060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Asp14428_72070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Asp14428_72080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Asp14428_72100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Asp14428_72110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Asp14428_72130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Asp14428_72140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Asp14428_72150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Asp14428_72160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Asp14428_72180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Asp14428_72190	COG0540	Belongs to the ATCase OTCase family
Asp14428_72200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asp14428_72210	COG0505	Belongs to the CarA family
Asp14428_72230	COG0167	dihydroorotate dehydrogenase activity
Asp14428_72240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Asp14428_72250	COG0284	orotidine-5'-phosphate decarboxylase activity
Asp14428_72260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Asp14428_72270	COG0194	GDP metabolic process
Asp14428_72290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Asp14428_72330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Asp14428_72340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Asp14428_72360	COG0242	peptide deformylase activity
Asp14428_72370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asp14428_72440	COG0745	RESPONSE REGULATOR receiver
Asp14428_72470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asp14428_72470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asp14428_72480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Asp14428_72500	COG0765	amino acid transport
Asp14428_72510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asp14428_72520	COG0140	phosphoribosyl-ATP diphosphatase activity
Asp14428_72530	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Asp14428_72550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Asp14428_72560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Asp14428_72570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Asp14428_72580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Asp14428_72590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Asp14428_72600	COG0072	phenylalanine-tRNA ligase activity
Asp14428_72600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asp14428_72700	COG1472	Belongs to the glycosyl hydrolase 3 family
Asp14428_72740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Asp14428_72750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Asp14428_72760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Asp14428_72770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Asp14428_72780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Asp14428_72790	COG1438	arginine binding
Asp14428_72810	COG0137	argininosuccinate synthase activity
Asp14428_72820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asp14428_72830	COG0165	Argininosuccinate lyase
Asp14428_72840	COG0730	response to heat
Asp14428_72860	COG0406	alpha-ribazole phosphatase activity
Asp14428_72870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Asp14428_72880	COG3537	Alpha-1,2-mannosidase
Asp14428_72900	COG2094	Belongs to the DNA glycosylase MPG family
Asp14428_72980	COG0563	adenylate kinase activity
Asp14428_72990	COG2326	polyphosphate kinase activity
Asp14428_73000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Asp14428_73030	COG0647	UMP catabolic process
Asp14428_73080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Asp14428_73160	COG0504	CTP synthase activity
Asp14428_73170	COG0494	nUDIX hydrolase
Asp14428_73290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Asp14428_73310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asp14428_73350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Asp14428_73370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Asp14428_73380	COG1187	pseudouridine synthase activity
Asp14428_73390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Asp14428_73400	COG1160	GTP binding
Asp14428_73460	COG3344	reverse transcriptase
Asp14428_73540	COG0252	asparaginase activity
Asp14428_73740	COG5002	protein histidine kinase activity
Asp14428_73740	COG2176	DNA-directed DNA polymerase activity
Asp14428_73750	COG3328	transposase activity
Asp14428_73770	COG2801	Transposase and inactivated derivatives
Asp14428_73820	COG3328	transposase activity
Asp14428_73840	COG1959	2 iron, 2 sulfur cluster binding
Asp14428_73920	COG2801	Transposase and inactivated derivatives
Asp14428_73930	COG3387	PFAM Glycoside hydrolase 15-related
Asp14428_73940	COG1063	alcohol dehydrogenase
Asp14428_73990	COG4948	Mandelate Racemase Muconate Lactonizing
Asp14428_74040	COG3547	Transposase (IS116 IS110 IS902 family)
Asp14428_74060	COG0789	Transcriptional regulator
Asp14428_74090	COG4935	Belongs to the peptidase S8 family
Asp14428_74090	COG2234	aminopeptidase activity
Asp14428_74120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Asp14428_74140	COG1131	(ABC) transporter
Asp14428_74220	COG0653	protein targeting
Asp14428_74410	COG1404	Belongs to the peptidase S8 family
Asp14428_74500	COG0604	alcohol dehydrogenase
Asp14428_74500	COG3321	synthase
Asp14428_74530	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asp14428_74550	COG0602	queuosine metabolic process
Asp14428_74560	COG0720	synthase
Asp14428_74570	COG0302	gtp cyclohydrolase
Asp14428_74590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Asp14428_74630	COG3629	intracellular signal transduction
Asp14428_74720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asp14428_74770	COG2197	response regulator
Asp14428_74790	COG2197	response regulator
Asp14428_74800	COG4585	Histidine kinase
Asp14428_74810	COG2409	Drug exporters of the RND superfamily
Asp14428_74850	COG3629	intracellular signal transduction
Asp14428_74850	COG3903	Transcriptional regulator
Asp14428_74870	COG3903	Transcriptional regulator
Asp14428_74870	COG3629	intracellular signal transduction
Asp14428_74900	COG2197	response regulator
Asp14428_75070	COG0464	growth
Asp14428_75100	COG2197	response regulator
Asp14428_75130	COG1902	pentaerythritol trinitrate reductase activity
Asp14428_75170	COG1733	regulation of RNA biosynthetic process
Asp14428_75180	COG0596	Alpha beta hydrolase
Asp14428_75190	COG1404	Belongs to the peptidase S8 family
Asp14428_75230	COG0444	Belongs to the ABC transporter superfamily
Asp14428_75300	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_75390	COG1404	Belongs to the peptidase S8 family
Asp14428_75410	COG0492	ferredoxin-NADP+ reductase activity
Asp14428_75450	COG4249	Peptidase C14 caspase catalytic subunit p20
Asp14428_75450	COG2319	Wd-40 repeat
Asp14428_75480	COG0535	radical SAM domain protein
Asp14428_75500	COG0535	radical SAM domain protein
Asp14428_75530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Asp14428_75560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asp14428_75620	COG0583	DNA-binding transcription factor activity
Asp14428_75630	COG0515	serine threonine protein kinase
Asp14428_75670	COG0667	Aldo Keto reductase
Asp14428_75700	COG3631	Ketosteroid isomerase-related protein
Asp14428_75800	COG2197	response regulator
Asp14428_75850	COG1846	Transcriptional regulator
Asp14428_75900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Asp14428_75910	COG0596	Alpha beta hydrolase
Asp14428_75960	COG2124	cytochrome p450
Asp14428_76110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asp14428_76110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asp14428_76110	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Asp14428_76130	COG1461	Dihydroxyacetone kinase
Asp14428_76140	COG2376	Dihydroxyacetone kinase
Asp14428_76200	COG3250	beta-galactosidase activity
Asp14428_76220	COG4221	oxidoreductase activity
Asp14428_76240	COG1028	Short-chain dehydrogenase reductase Sdr
Asp14428_76270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asp14428_76290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asp14428_76310	COG1695	Transcriptional regulator
Asp14428_76330	COG0475	glutathione-regulated potassium exporter activity
Asp14428_76350	COG4585	Histidine kinase
Asp14428_76360	COG2197	response regulator
Asp14428_76380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Asp14428_76380	COG0825	malonyl-CoA metabolic process
Asp14428_76390	COG0511	ligase activity, forming carbon-carbon bonds
Asp14428_76400	COG0439	Biotin carboxylase
Asp14428_76460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asp14428_76490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Asp14428_76530	COG2132	Multicopper oxidase
Asp14428_76550	COG2200	EAL domain
Asp14428_76550	COG3287	FIST C domain
Asp14428_76550	COG2199	diguanylate cyclase activity
Asp14428_76580	COG0596	Alpha beta hydrolase
Asp14428_76590	COG0346	lactoylglutathione lyase activity
Asp14428_76630	COG1595	DNA-templated transcription, initiation
Asp14428_76660	COG2264	protein methyltransferase activity
Asp14428_76670	COG1278	Cold shock
Asp14428_76720	COG0667	Aldo Keto reductase
Asp14428_76780	COG2198	Histidine kinase
Asp14428_76780	COG0643	Histidine kinase
Asp14428_76820	COG2201	protein-glutamate methylesterase activity
Asp14428_76830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Asp14428_76850	COG0835	chemotaxis
Asp14428_76900	COG1716	ATPase activity
Asp14428_76910	COG2197	response regulator
Asp14428_76920	COG4585	Histidine kinase
Asp14428_76940	COG2197	response regulator
Asp14428_76960	COG1024	Enoyl-CoA hydratase
Asp14428_76970	COG0515	serine threonine protein kinase
Asp14428_76980	COG0477	Major facilitator Superfamily
Asp14428_77020	COG1309	transcriptional regulator
Asp14428_77070	COG0277	FAD linked oxidase domain protein
Asp14428_77310	COG1252	NADH dehydrogenase
Asp14428_77320	COG1132	(ABC) transporter
Asp14428_77350	COG2409	Drug exporters of the RND superfamily
Asp14428_77360	COG1129	ABC transporter
Asp14428_77370	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asp14428_77380	COG4213	ABC transporter substrate-binding protein
Asp14428_77390	COG1940	carbohydrate kinase activity
Asp14428_77460	COG0477	Major facilitator Superfamily
Asp14428_77490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_77500	COG1116	anion transmembrane transporter activity
Asp14428_77510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asp14428_77540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asp14428_77570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Asp14428_77580	COG5002	protein histidine kinase activity
Asp14428_77580	COG5001	Diguanylate cyclase
Asp14428_77590	COG1595	DNA-templated transcription, initiation
Asp14428_77620	COG2319	Wd-40 repeat
Asp14428_77620	COG5635	Nacht domain
Asp14428_77640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Asp14428_77660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Asp14428_77670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asp14428_77690	COG1414	Transcriptional regulator
Asp14428_77700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asp14428_77710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asp14428_77780	COG0584	glycerophosphoryl diester phosphodiesterase
Asp14428_77790	COG0673	inositol 2-dehydrogenase activity
Asp14428_77830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Asp14428_77870	COG5297	Belongs to the glycosyl hydrolase family 6
Asp14428_77890	COG0010	Belongs to the arginase family
Asp14428_77970	COG2183	response to ionizing radiation
Asp14428_78030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Asp14428_78060	COG0366	Alpha amylase catalytic
Asp14428_78110	COG1063	alcohol dehydrogenase
Asp14428_78130	COG1191	sigma factor activity
Asp14428_78220	COG2801	Transposase and inactivated derivatives
Asp14428_78300	COG5002	protein histidine kinase activity
Asp14428_78310	COG0784	Response regulator, receiver
Asp14428_78320	COG0656	L-ascorbic acid biosynthetic process
Asp14428_78330	COG1643	Atp-dependent helicase
Asp14428_78410	COG5001	Diguanylate cyclase
Asp14428_78420	COG0589	response to stress
Asp14428_78460	COG0640	Transcriptional regulator
Asp14428_78470	COG1070	Carbohydrate kinase
Asp14428_78500	COG1797	cobyrinic acid a,c-diamide synthase activity
Asp14428_78650	COG1132	(ABC) transporter
Asp14428_78660	COG0653	protein targeting
Asp14428_78700	COG0745	RESPONSE REGULATOR receiver
Asp14428_78840	COG0542	response to heat
Asp14428_78850	COG0583	DNA-binding transcription factor activity
Asp14428_78870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asp14428_78900	COG0667	Aldo Keto reductase
Asp14428_78910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asp14428_78950	COG0215	cysteine-tRNA ligase activity
Asp14428_78960	COG1902	pentaerythritol trinitrate reductase activity
Asp14428_79090	COG0667	Aldo Keto reductase
Asp14428_79110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asp14428_79120	COG4221	oxidoreductase activity
Asp14428_79150	COG0577	efflux transmembrane transporter activity
Asp14428_79150	COG1136	(ABC) transporter
Asp14428_79180	COG2197	response regulator
Asp14428_79200	COG0517	IMP dehydrogenase activity
Asp14428_79200	COG1994	Peptidase M50
Asp14428_79230	COG1141	Ferredoxin
Asp14428_79240	COG1222	aaa ATPase
Asp14428_79250	COG4122	O-methyltransferase activity
Asp14428_79270	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asp14428_79280	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asp14428_79310	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asp14428_79370	COG2378	regulation of single-species biofilm formation
Asp14428_79390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asp14428_79400	COG0805	protein transport
Asp14428_79430	COG0546	phosphoglycolate phosphatase activity
Asp14428_79460	COG1609	Transcriptional regulator
Asp14428_79530	COG2304	oxidoreductase activity
Asp14428_79550	COG0515	serine threonine protein kinase
Asp14428_79570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asp14428_79590	COG0318	PFAM AMP-dependent synthetase and ligase
Asp14428_79620	COG2197	response regulator
Asp14428_79650	COG1653	transport
Asp14428_79690	COG2409	Drug exporters of the RND superfamily
Asp14428_79700	COG4585	Histidine kinase
Asp14428_79710	COG2197	response regulator
Asp14428_79760	COG0142	geranyltranstransferase activity
Asp14428_79790	COG1960	acyl-CoA dehydrogenase activity
Asp14428_79820	COG1960	acyl-CoA dehydrogenase activity
Asp14428_79940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Asp14428_80020	COG1309	transcriptional regulator
Asp14428_80040	COG2197	response regulator
Asp14428_80050	COG4585	Histidine kinase
Asp14428_80060	COG1136	(ABC) transporter
Asp14428_80060	COG0577	efflux transmembrane transporter activity
Asp14428_80070	COG1136	(ABC) transporter
Asp14428_80070	COG0577	efflux transmembrane transporter activity
Asp14428_80100	COG4251	negative regulation of phosphorylation
Asp14428_80110	COG2201	protein-glutamate methylesterase activity
Asp14428_80130	COG0840	transmembrane signaling receptor activity
Asp14428_80150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Asp14428_80220	COG0577	efflux transmembrane transporter activity
Asp14428_80220	COG1136	(ABC) transporter
Asp14428_80230	COG1136	(ABC) transporter
Asp14428_80230	COG0577	efflux transmembrane transporter activity
Asp14428_80240	COG5006	permease, DMT superfamily
Asp14428_80250	COG5001	Diguanylate cyclase
Asp14428_80250	COG3300	MHYT domain
Asp14428_80340	COG1609	Transcriptional regulator
Asp14428_80370	COG2160	L-arabinose isomerase activity
Asp14428_80390	COG1129	ABC transporter
Asp14428_80400	COG4214	carbohydrate transport
Asp14428_80440	COG1940	carbohydrate kinase activity
Asp14428_80470	COG1366	Belongs to the anti-sigma-factor antagonist family
Asp14428_80480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Asp14428_80510	COG2501	S4 domain