locus-tag	class	description
CDG81_00010	COG0592	DNA-directed DNA polymerase activity
CDG81_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CDG81_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG81_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CDG81_00030	COG0187	DNA topoisomerase II activity
CDG81_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDG81_00070	COG0789	Transcriptional regulator
CDG81_00120	COG3764	Sortase (surface protein transpeptidase)
CDG81_00130	COG0569	domain protein
CDG81_00135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG81_00145	COG0515	serine threonine protein kinase
CDG81_00145	COG2815	serine threonine protein kinase
CDG81_00150	COG0515	serine threonine protein kinase
CDG81_00155	COG0768	penicillin binding
CDG81_00170	COG1716	ATPase activity
CDG81_00175	COG1716	ATPase activity
CDG81_00195	COG0586	Pfam SNARE associated Golgi protein
CDG81_00200	COG3973	AAA domain
CDG81_00205	COG0789	Transcriptional regulator
CDG81_00220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG81_00245	COG1253	flavin adenine dinucleotide binding
CDG81_00260	COG2807	transmembrane transport
CDG81_00265	COG1414	Transcriptional regulator
CDG81_00350	COG1309	transcriptional regulator
CDG81_00380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG81_00405	COG0667	Aldo Keto reductase
CDG81_00415	COG1690	Belongs to the RtcB family
CDG81_00430	COG1216	Glycosyl transferase, family 2
CDG81_00430	COG0438	transferase activity, transferring glycosyl groups
CDG81_00445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG81_00450	COG3397	chitin binding
CDG81_00455	COG3360	Dodecin
CDG81_00475	COG3275	phosphorelay sensor kinase activity
CDG81_00495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_00500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDG81_00515	COG1528	Iron-storage protein
CDG81_00530	COG2814	Major facilitator Superfamily
CDG81_00540	COG2376	Dihydroxyacetone kinase
CDG81_00545	COG0698	ribose 5-phosphate isomerase
CDG81_00565	COG2259	Doxx family
CDG81_00620	COG2235	arginine
CDG81_00655	COG1271	oxidase subunit
CDG81_00660	COG1294	oxidase, subunit
CDG81_00665	COG4988	ABC transporter
CDG81_00685	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CDG81_00705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDG81_00715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_00720	COG0561	phosphatase activity
CDG81_00735	COG1216	Glycosyl transferase, family 2
CDG81_00745	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG81_00750	COG0442	prolyl-tRNA aminoacylation
CDG81_00775	COG5479	isomerase activity
CDG81_00775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDG81_00810	COG1216	Glycosyl transferase, family 2
CDG81_00835	COG2234	aminopeptidase activity
CDG81_00845	COG1131	(ABC) transporter
CDG81_00865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDG81_00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG81_00890	COG4974	Belongs to the 'phage' integrase family
CDG81_00960	COG0183	Belongs to the thiolase family
CDG81_00965	COG0287	Prephenate dehydrogenase
CDG81_00975	COG0590	tRNA wobble adenosine to inosine editing
CDG81_00980	COG3237	CsbD-like
CDG81_01015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDG81_01020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG81_01050	COG4608	Belongs to the ABC transporter superfamily
CDG81_01060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG81_01110	COG2610	gluconate transmembrane transporter activity
CDG81_01135	COG5650	phosphatidylinositol metabolic process
CDG81_01160	COG2197	response regulator
CDG81_01170	COG0431	NADPH-dependent FMN reductase
CDG81_01195	COG1131	(ABC) transporter
CDG81_01205	COG1902	pentaerythritol trinitrate reductase activity
CDG81_01220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG81_01225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG81_01240	COG0494	nUDIX hydrolase
CDG81_01245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDG81_01270	COG0071	Belongs to the small heat shock protein (HSP20) family
CDG81_01275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG81_01310	COG0003	Pfam Anion-transporting ATPase
CDG81_01335	COG1408	metallophosphoesterase
CDG81_01350	COG0823	Involved in the tonB-independent uptake of proteins
CDG81_01350	COG1506	peptidase
CDG81_01350	COG4946	Tricorn protease homolog
CDG81_01370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDG81_01375	COG1737	Transcriptional regulator
CDG81_01390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDG81_01395	COG3876	Protein conserved in bacteria
CDG81_01400	COG1472	Belongs to the glycosyl hydrolase 3 family
CDG81_01465	COG1205	dead DEAH box helicase
CDG81_01465	COG1111	helicase
CDG81_01470	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDG81_01480	COG1754	DNA topoisomerase type I activity
CDG81_01480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDG81_01485	COG0470	DNA polymerase III
CDG81_01530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG81_01545	COG0037	tRNA processing
CDG81_01555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG81_01560	COG0302	gtp cyclohydrolase
CDG81_01600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDG81_01605	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CDG81_01610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDG81_01615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDG81_01635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_01640	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_01645	COG1120	ATPase activity
CDG81_01650	COG0542	response to heat
CDG81_01685	COG0471	metal ion transport
CDG81_01715	COG1511	domain protein
CDG81_01720	COG1121	(ABC) transporter
CDG81_01725	COG2226	methyltransferase
CDG81_01740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDG81_01755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDG81_01765	COG0546	phosphoglycolate phosphatase activity
CDG81_01770	COG0215	cysteine-tRNA ligase activity
CDG81_01790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG81_01795	COG1120	ATPase activity
CDG81_01810	COG1609	Transcriptional regulator
CDG81_01825	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDG81_01855	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CDG81_01870	COG0582	viral genome integration into host DNA
CDG81_01885	COG0305	Participates in initiation and elongation during chromosome replication
CDG81_02000	COG1857	crispr-associated protein
CDG81_02090	COG1063	alcohol dehydrogenase
CDG81_02095	COG2318	DinB family
CDG81_02110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG81_02115	COG2072	flavoprotein involved in K transport
CDG81_02190	COG0456	acetyltransferase
CDG81_02200	COG1917	Cupin 2, conserved barrel domain protein
CDG81_02210	COG3903	Transcriptional regulator
CDG81_02210	COG3629	intracellular signal transduction
CDG81_02240	COG2971	BadF BadG BcrA BcrD
CDG81_02245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG81_02250	COG2188	Transcriptional regulator
CDG81_02270	COG0352	thiamine-phosphate diphosphorylase activity
CDG81_02285	COG2022	thiamine diphosphate biosynthetic process
CDG81_02290	COG3311	Transcriptional regulator
CDG81_02295	COG1569	PIN domain
CDG81_02325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDG81_02350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG81_02365	COG0688	phosphatidylethanolamine metabolic process
CDG81_02385	COG1278	Cold shock
CDG81_02395	COG0459	protein refolding
CDG81_02400	COG3291	Pkd domain containing protein
CDG81_02400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CDG81_02420	COG1278	Cold shock
CDG81_02460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG81_02465	COG3311	Transcriptional regulator
CDG81_02470	COG1569	PIN domain
CDG81_02505	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_02515	COG1061	Type III restriction enzyme res subunit
CDG81_02530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG81_02550	COG2018	Roadblock/LC7 domain
CDG81_02580	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG81_02595	COG1652	LysM domain
CDG81_02605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG81_02635	COG3304	Inner membrane component domain
CDG81_02640	COG0384	phenazine biosynthesis protein PhzF
CDG81_02680	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_02705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG81_02755	COG2814	Major facilitator Superfamily
CDG81_02770	COG2814	Major facilitator Superfamily
CDG81_02775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_02800	COG5002	protein histidine kinase activity
CDG81_02805	COG0745	RESPONSE REGULATOR receiver
CDG81_02835	COG0577	efflux transmembrane transporter activity
CDG81_02835	COG1136	(ABC) transporter
CDG81_02865	COG0259	pyridoxamine-phosphate oxidase activity
CDG81_02870	COG2017	converts alpha-aldose to the beta-anomer
CDG81_02875	COG1960	acyl-CoA dehydrogenase activity
CDG81_02885	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDG81_02885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDG81_02895	COG1668	transmembrane transport
CDG81_02900	COG4152	abc transporter atp-binding protein
CDG81_02910	COG2130	NADP-dependent
CDG81_02920	COG1674	ftsk spoiiie
CDG81_02945	COG2267	carboxylic ester hydrolase activity
CDG81_02965	COG0596	Alpha beta hydrolase
CDG81_02970	COG0438	transferase activity, transferring glycosyl groups
CDG81_02980	COG0667	Aldo Keto reductase
CDG81_02985	COG0346	lactoylglutathione lyase activity
CDG81_02995	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_03000	COG2205	protein histidine kinase activity
CDG81_03005	COG0745	RESPONSE REGULATOR receiver
CDG81_03010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDG81_03010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDG81_03040	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDG81_03040	COG1672	PFAM Archaeal ATPase
CDG81_03050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDG81_03065	COG1937	Protein conserved in bacteria
CDG81_03150	COG2130	NADP-dependent
CDG81_03155	COG0667	Aldo Keto reductase
CDG81_03160	COG1846	Transcriptional regulator
CDG81_03165	COG1309	transcriptional regulator
CDG81_03190	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDG81_03235	COG2197	response regulator
CDG81_03260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG81_03260	COG4651	solute:proton antiporter activity
CDG81_03310	COG1982	Orn Lys Arg decarboxylase major
CDG81_03320	COG1024	Enoyl-CoA hydratase
CDG81_03365	COG0582	viral genome integration into host DNA
CDG81_03395	COG0745	RESPONSE REGULATOR receiver
CDG81_03395	COG3706	GGDEF domain
CDG81_03400	COG0778	Nitroreductase
CDG81_03410	COG2205	protein histidine kinase activity
CDG81_03415	COG1349	DNA-binding transcription factor activity
CDG81_03430	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG81_03430	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDG81_03450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG81_03455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG81_03465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDG81_03500	COG0583	DNA-binding transcription factor activity
CDG81_03510	COG0800	Aldolase
CDG81_03515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG81_03520	COG3386	PFAM SMP-30 Gluconolaconase
CDG81_03525	COG2186	Transcriptional regulator
CDG81_03530	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_03535	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_03550	COG2197	response regulator
CDG81_03560	COG1131	(ABC) transporter
CDG81_03590	COG1215	transferase activity, transferring glycosyl groups
CDG81_03595	COG1032	radical SAM domain protein
CDG81_03615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDG81_03630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG81_03640	COG0515	serine threonine protein kinase
CDG81_03645	COG2111	Na H antiporter
CDG81_03645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG81_03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG81_03695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CDG81_03695	COG1473	amidohydrolase
CDG81_03750	COG2321	neutral zinc metallopeptidase
CDG81_03760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDG81_03765	COG0424	maF-like protein
CDG81_03770	COG1301	dicarboxylic acid transport
CDG81_03775	COG4770	biotin carboxylase activity
CDG81_03805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDG81_03810	COG1349	DNA-binding transcription factor activity
CDG81_03815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDG81_03820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG81_03825	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG81_03840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_03890	COG0110	maltose O-acetyltransferase activity
CDG81_03895	COG3226	Transcriptional regulator
CDG81_03955	COG0483	inositol monophosphate 1-phosphatase activity
CDG81_03960	COG0745	RESPONSE REGULATOR receiver
CDG81_03965	COG2205	protein histidine kinase activity
CDG81_03980	COG1136	(ABC) transporter
CDG81_03990	COG3940	Belongs to the glycosyl hydrolase 43 family
CDG81_04075	COG1316	TRANSCRIPTIONal
CDG81_04080	COG1316	TRANSCRIPTIONal
CDG81_04100	COG0438	transferase activity, transferring glycosyl groups
CDG81_04105	COG0438	transferase activity, transferring glycosyl groups
CDG81_04135	COG0438	transferase activity, transferring glycosyl groups
CDG81_04205	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CDG81_04205	COG0778	Nitroreductase
CDG81_04215	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_04220	COG1994	Peptidase M50
CDG81_04260	COG1482	cell wall glycoprotein biosynthetic process
CDG81_04265	COG0531	amino acid
CDG81_04280	COG0745	RESPONSE REGULATOR receiver
CDG81_04285	COG5000	phosphorelay sensor kinase activity
CDG81_04285	COG5002	protein histidine kinase activity
CDG81_04290	COG5401	PFAM Sporulation and spore germination
CDG81_04300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDG81_04305	COG0653	protein targeting
CDG81_04335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_04360	COG1162	GTPase activity
CDG81_04365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG81_04390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDG81_04405	COG1597	lipid kinase activity
CDG81_04455	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDG81_04460	COG0281	malic enzyme
CDG81_04465	COG5001	Diguanylate cyclase
CDG81_04480	COG1174	glycine betaine transport
CDG81_04515	COG2986	histidine ammonia-lyase
CDG81_04520	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDG81_04530	COG0402	S-adenosylhomocysteine deaminase activity
CDG81_04535	COG1228	amidohydrolase
CDG81_04560	COG1063	alcohol dehydrogenase
CDG81_04580	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDG81_04580	COG0567	Dehydrogenase, E1 component
CDG81_04590	COG1132	(ABC) transporter
CDG81_04600	COG0671	phosphoesterase, PA-phosphatase related
CDG81_04735	COG0071	Belongs to the small heat shock protein (HSP20) family
CDG81_04760	COG0686	Belongs to the AlaDH PNT family
CDG81_04765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CDG81_04765	COG2508	Transcriptional regulator
CDG81_04770	COG0509	glycine decarboxylation via glycine cleavage system
CDG81_04775	COG1760	l-serine dehydratase
CDG81_04790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG81_04835	COG0277	FAD linked oxidase domain protein
CDG81_04840	COG0277	FAD linked oxidase domain protein
CDG81_04845	COG0247	lactate metabolic process
CDG81_04855	COG0183	Belongs to the thiolase family
CDG81_04860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_04860	COG1024	Enoyl-CoA hydratase
CDG81_04900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG81_04940	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_04975	COG0831	urea catabolic process
CDG81_04980	COG0832	Belongs to the urease beta subunit family
CDG81_04985	COG0804	urea catabolic process
CDG81_04995	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CDG81_05000	COG0829	nickel cation binding
CDG81_05015	COG4172	Belongs to the ABC transporter superfamily
CDG81_05020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_05030	COG4166	transmembrane transport
CDG81_05040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG81_05055	COG5001	Diguanylate cyclase
CDG81_05065	COG0477	Major facilitator Superfamily
CDG81_05085	COG0582	viral genome integration into host DNA
CDG81_05100	COG0018	arginyl-trna synthetase
CDG81_05105	COG0019	diaminopimelate decarboxylase activity
CDG81_05110	COG0460	homoserine dehydrogenase
CDG81_05115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG81_05120	COG0083	homoserine kinase activity
CDG81_05125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDG81_05130	COG0254	rRNA binding
CDG81_05135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDG81_05140	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG81_05155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDG81_05165	COG0356	it plays a direct role in the translocation of protons across the membrane
CDG81_05175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDG81_05180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDG81_05185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDG81_05190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDG81_05195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG81_05200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDG81_05250	COG1280	lysine exporter protein (LysE YggA)
CDG81_05260	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CDG81_05290	COG2376	Dihydroxyacetone kinase
CDG81_05295	COG1461	Dihydroxyacetone kinase
CDG81_05300	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CDG81_05325	COG2267	carboxylic ester hydrolase activity
CDG81_05340	COG1309	transcriptional regulator
CDG81_05350	COG0183	Belongs to the thiolase family
CDG81_05370	COG1846	Transcriptional regulator
CDG81_05400	COG0058	SHG alpha-glucan phosphorylase activity
CDG81_05405	COG1119	ATPase activity
CDG81_05420	COG1643	Atp-dependent helicase
CDG81_05425	COG1307	EDD domain protein, DegV family
CDG81_05435	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDG81_05460	COG0482	sulfurtransferase activity
CDG81_05475	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG81_05480	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_05505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG81_05545	COG0109	protoheme IX farnesyltransferase activity
CDG81_05560	COG1414	Transcriptional regulator
CDG81_05565	COG0149	triose-phosphate isomerase activity
CDG81_05575	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CDG81_05580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG81_05580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDG81_05585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG81_05610	COG3290	protein histidine kinase activity
CDG81_05615	COG4565	transcriptional regulatory protein
CDG81_05620	COG0456	acetyltransferase
CDG81_05675	COG2902	Dehydrogenase
CDG81_05680	COG0824	Thioesterase
CDG81_05690	COG0366	Alpha amylase catalytic
CDG81_05695	COG0366	Alpha amylase catalytic
CDG81_05705	COG0668	transmembrane transport
CDG81_05710	COG1505	serine-type exopeptidase activity
CDG81_05745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG81_05770	COG2814	Major facilitator Superfamily
CDG81_05790	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDG81_05795	COG0740	serine-type endopeptidase activity
CDG81_05800	COG0740	serine-type endopeptidase activity
CDG81_05805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDG81_05815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDG81_05820	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_05820	COG3773	Cell wall hydrolase
CDG81_05855	COG0525	valine-tRNA ligase activity
CDG81_05860	COG0285	dihydrofolate synthase activity
CDG81_05870	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG81_05875	COG0105	UTP biosynthetic process
CDG81_05885	COG1032	radical SAM domain protein
CDG81_05895	COG1530	ribonuclease E activity
CDG81_05895	COG1530	ribonuclease E activity
CDG81_05915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDG81_05920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDG81_05925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDG81_05935	COG0514	ATP-dependent DNA helicase (RecQ)
CDG81_05955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDG81_05970	COG1307	EDD domain protein, DegV family
CDG81_05995	COG0268	Binds directly to 16S ribosomal RNA
CDG81_06020	COG3311	Transcriptional regulator
CDG81_06035	COG0481	GTPase activity
CDG81_06065	COG1960	acyl-CoA dehydrogenase activity
CDG81_06070	COG1024	Enoyl-CoA hydratase
CDG81_06085	COG2732	(Barnase) inhibitor
CDG81_06100	COG4941	Belongs to the sigma-70 factor family
CDG81_06165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_06175	COG1420	regulation of RNA biosynthetic process
CDG81_06180	COG0484	heat shock protein binding
CDG81_06190	COG0537	adenosine 5'-monophosphoramidase activity
CDG81_06200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDG81_06215	COG1846	Transcriptional regulator
CDG81_06220	COG0038	chloride channel
CDG81_06225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG81_06240	COG1381	Involved in DNA repair and RecF pathway recombination
CDG81_06250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG81_06270	COG0423	glycine-tRNA ligase activity
CDG81_06280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CDG81_06310	COG4106	trans-aconitate 2-methyltransferase activity
CDG81_06380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_06420	COG4585	Histidine kinase
CDG81_06425	COG2197	response regulator
CDG81_06445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG81_06450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDG81_06470	COG3201	nicotinamide mononucleotide transporter
CDG81_06475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CDG81_06540	COG2119	membrane
CDG81_06545	COG3268	Saccharopine dehydrogenase
CDG81_06580	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDG81_06605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG81_06615	COG0406	alpha-ribazole phosphatase activity
CDG81_06615	COG0328	RNA-DNA hybrid ribonuclease activity
CDG81_06620	COG1940	carbohydrate kinase activity
CDG81_06625	COG0477	Major facilitator Superfamily
CDG81_06680	COG0557	exoribonuclease II activity
CDG81_06690	COG0435	Glutathione S-transferase
CDG81_06695	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDG81_06730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG81_06730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG81_06740	COG0174	glutamine synthetase
CDG81_06775	COG1595	DNA-templated transcription, initiation
CDG81_06805	COG1376	ErfK ybiS ycfS ynhG family protein
CDG81_06820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG81_06825	COG1214	PFAM Peptidase M22, glycoprotease
CDG81_06825	COG0456	acetyltransferase
CDG81_06835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG81_06850	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG81_06865	COG0129	dihydroxy-acid dehydratase activity
CDG81_06880	COG0440	acetolactate synthase activity
CDG81_06885	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDG81_06895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG81_06900	COG0473	3-isopropylmalate dehydrogenase activity
CDG81_06905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG81_06910	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG81_06920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG81_06950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG81_06955	COG0066	3-isopropylmalate dehydratase activity
CDG81_06985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDG81_06990	COG0626	cystathionine gamma-synthase activity
CDG81_07005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_07030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDG81_07035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDG81_07040	COG1461	Dihydroxyacetone kinase
CDG81_07050	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDG81_07055	COG0742	ribosomal rna small subunit methyltransferase
CDG81_07060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDG81_07085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDG81_07090	COG0571	ribonuclease III activity
CDG81_07095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDG81_07100	COG0367	asparagine synthase
CDG81_07105	COG1072	(Pantothenic acid kinase))
CDG81_07115	COG1254	Belongs to the acylphosphatase family
CDG81_07120	COG1196	nuclear chromosome segregation
CDG81_07125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_07130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG81_07150	COG4133	protoheme IX ABC transporter activity
CDG81_07180	COG0228	four-way junction DNA binding
CDG81_07190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG81_07195	COG0336	Belongs to the RNA methyltransferase TrmD family
CDG81_07200	COG0335	large ribosomal subunit rRNA binding
CDG81_07205	COG0681	Belongs to the peptidase S26 family
CDG81_07210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG81_07220	COG0792	nuclease activity
CDG81_07225	COG0606	chelatase, subunit chli
CDG81_07240	COG1191	sigma factor activity
CDG81_07250	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG81_07255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDG81_07260	COG0528	UMP kinase activity
CDG81_07265	COG0233	cytoplasmic translational termination
CDG81_07270	COG0575	Belongs to the CDS family
CDG81_07290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDG81_07300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDG81_07305	COG0750	zinc metalloprotease
CDG81_07310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDG81_07320	COG0768	penicillin binding
CDG81_07335	COG1492	cobalamin metabolic process
CDG81_07340	COG2186	Transcriptional regulator
CDG81_07345	COG2807	transmembrane transport
CDG81_07390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDG81_07395	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_07410	COG3420	alginic acid biosynthetic process
CDG81_07440	COG1881	PFAM PEBP family protein
CDG81_07450	COG1280	lysine exporter protein (LysE YggA)
CDG81_07460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG81_07510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG81_07510	COG1648	precorrin-2 dehydrogenase activity
CDG81_07520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_07555	COG3022	response to hydroperoxide
CDG81_07565	COG0442	prolyl-tRNA aminoacylation
CDG81_07575	COG0432	Pfam Uncharacterised protein family UPF0047
CDG81_07600	COG0779	Required for maturation of 30S ribosomal subunits
CDG81_07615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDG81_07620	COG1550	Protein conserved in bacteria
CDG81_07625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG81_07640	COG0242	peptide deformylase activity
CDG81_07645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG81_07665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDG81_07670	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG81_07710	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CDG81_07720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG81_07725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDG81_07735	COG0596	Alpha beta hydrolase
CDG81_07750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDG81_07760	COG1058	Belongs to the CinA family
CDG81_07760	COG1546	Belongs to the CinA family
CDG81_07765	COG1396	sequence-specific DNA binding
CDG81_07780	COG2233	PERMEase
CDG81_07785	COG1192	Involved in chromosome partitioning
CDG81_07790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG81_07800	COG1305	Transglutaminase-like
CDG81_07810	COG0714	Associated with various cellular activities
CDG81_07815	COG0275	rRNA processing
CDG81_07840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDG81_07845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDG81_07855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDG81_07860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG81_07890	COG1799	cell septum assembly
CDG81_07910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG81_07915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDG81_07920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDG81_07935	COG0587	DNA-directed DNA polymerase activity
CDG81_07940	COG2124	cytochrome p450
CDG81_07970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG81_08010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_08030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG81_08035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDG81_08040	COG0131	Imidazoleglycerol-phosphate dehydratase
CDG81_08060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG81_08070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDG81_08075	COG0107	imidazoleglycerol-phosphate synthase activity
CDG81_08090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDG81_08100	COG0134	indole-3-glycerol-phosphate synthase activity
CDG81_08105	COG0133	tryptophan synthase activity
CDG81_08110	COG0159	tryptophan synthase activity
CDG81_08115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDG81_08120	COG1120	ATPase activity
CDG81_08125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_08130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDG81_08140	COG2186	Transcriptional regulator
CDG81_08160	COG1946	Acyl-CoA thioesterase
CDG81_08170	COG1280	lysine exporter protein (LysE YggA)
CDG81_08175	COG2027	D-alanyl-D-alanine carboxypeptidase
CDG81_08180	COG0586	Pfam SNARE associated Golgi protein
CDG81_08185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDG81_08190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDG81_08195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDG81_08205	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_08215	COG1960	acyl-CoA dehydrogenase activity
CDG81_08220	COG5441	Belongs to the UPF0261 family
CDG81_08225	COG5564	TIM-barrel signal transduction protein
CDG81_08235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG81_08250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG81_08280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG81_08280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG81_08285	COG1802	Transcriptional regulator
CDG81_08300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDG81_08305	COG0022	dehydrogenase e1 component
CDG81_08310	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDG81_08330	COG5001	Diguanylate cyclase
CDG81_08330	COG3300	MHYT domain
CDG81_08390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDG81_08395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDG81_08395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDG81_08420	COG1764	response to oxidative stress
CDG81_08425	COG0640	Transcriptional regulator
CDG81_08430	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDG81_08440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDG81_08460	COG4311	Sarcosine oxidase, delta subunit
CDG81_08475	COG1414	Transcriptional regulator
CDG81_08485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDG81_08490	COG1414	Transcriptional regulator
CDG81_08505	COG1733	regulation of RNA biosynthetic process
CDG81_08515	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_08530	COG1960	acyl-CoA dehydrogenase activity
CDG81_08540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDG81_08545	COG1070	Carbohydrate kinase
CDG81_08590	COG0395	ABC-type sugar transport system, permease component
CDG81_08655	COG2050	protein possibly involved in aromatic compounds catabolism
CDG81_08685	COG2226	methyltransferase
CDG81_08690	COG0539	negative regulation of cytoplasmic translation
CDG81_08715	COG1960	acyl-CoA dehydrogenase activity
CDG81_08720	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_08730	COG1024	Enoyl-CoA hydratase
CDG81_08740	COG0583	DNA-binding transcription factor activity
CDG81_08780	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_08820	COG1011	Hydrolase
CDG81_08840	COG3226	Transcriptional regulator
CDG81_08860	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_08860	COG3757	hydrolase, family 25
CDG81_08865	COG0438	transferase activity, transferring glycosyl groups
CDG81_08870	COG2226	methyltransferase
CDG81_08890	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_08900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_08915	COG0662	Cupin 2, conserved barrel domain protein
CDG81_08950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG81_08965	COG1309	transcriptional regulator
CDG81_08970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDG81_08970	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDG81_08975	COG1013	pyruvate-flavodoxin oxidoreductase activity
CDG81_08995	COG0492	ferredoxin-NADP+ reductase activity
CDG81_09005	COG0438	transferase activity, transferring glycosyl groups
CDG81_09015	COG3858	chitin binding
CDG81_09015	COG1388	LysM domain
CDG81_09025	COG2197	response regulator
CDG81_09030	COG0438	transferase activity, transferring glycosyl groups
CDG81_09040	COG2017	converts alpha-aldose to the beta-anomer
CDG81_09045	COG3250	beta-galactosidase activity
CDG81_09055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG81_09070	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG81_09135	COG1024	Enoyl-CoA hydratase
CDG81_09140	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_09150	COG0477	Major facilitator Superfamily
CDG81_09155	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_09180	COG1716	ATPase activity
CDG81_09195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDG81_09195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDG81_09225	COG3104	oligopeptide transport
CDG81_09250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDG81_09255	COG0121	glutamine amidotransferase
CDG81_09260	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CDG81_09275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDG81_09310	COG2146	nitrite reductase [NAD(P)H] activity
CDG81_09310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_09315	COG2146	nitrite reductase [NAD(P)H] activity
CDG81_09315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_09320	COG0243	molybdopterin cofactor binding
CDG81_09325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDG81_09330	COG3883	PFAM NLP P60 protein
CDG81_09330	COG0791	NLP P60 protein
CDG81_09340	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDG81_09345	COG0346	lactoylglutathione lyase activity
CDG81_09350	COG0400	carboxylic ester hydrolase activity
CDG81_09365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG81_09370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG81_09380	COG3485	protocatechuate 3,4-dioxygenase
CDG81_09385	COG3485	protocatechuate 3,4-dioxygenase
CDG81_09390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDG81_09395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG81_09400	COG1414	Transcriptional regulator
CDG81_09405	COG1132	(ABC) transporter
CDG81_09410	COG2183	response to ionizing radiation
CDG81_09415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDG81_09435	COG1233	COG1233 Phytoene dehydrogenase and related
CDG81_09445	COG1657	PFAM Prenyltransferase squalene oxidase
CDG81_09465	COG0300	oxidoreductase activity
CDG81_09470	COG0697	spore germination
CDG81_09475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDG81_09485	COG1349	DNA-binding transcription factor activity
CDG81_09510	COG0589	response to stress
CDG81_09525	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG81_09535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CDG81_09725	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CDG81_09730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG81_09730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG81_09755	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_09765	COG1966	Carbon starvation protein
CDG81_09780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG81_09795	COG0484	heat shock protein binding
CDG81_09800	COG2807	transmembrane transport
CDG81_09825	COG2706	6-phosphogluconolactonase activity
CDG81_09830	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDG81_09840	COG1414	Transcriptional regulator
CDG81_09845	COG0251	oxidation-reduction process
CDG81_09865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDG81_09870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDG81_09875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_09880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDG81_09885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG81_09885	COG0072	phenylalanine-tRNA ligase activity
CDG81_09890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDG81_09895	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG81_09900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG81_09910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDG81_09920	COG0137	argininosuccinate synthase activity
CDG81_09925	COG0165	Argininosuccinate lyase
CDG81_09930	COG2094	Belongs to the DNA glycosylase MPG family
CDG81_09935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG81_09960	COG0647	UMP catabolic process
CDG81_09975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG81_10000	COG0504	CTP synthase activity
CDG81_10020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG81_10025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG81_10035	COG0475	glutathione-regulated potassium exporter activity
CDG81_10055	COG1160	GTP binding
CDG81_10060	COG0656	L-ascorbic acid biosynthetic process
CDG81_10070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDG81_10080	COG1324	tolerance protein
CDG81_10090	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDG81_10115	COG0070	glutamate synthase
CDG81_10115	COG0069	glutamate synthase activity
CDG81_10115	COG0067	glutamate synthase
CDG81_10135	COG0730	response to heat
CDG81_10140	COG0746	molybdenum cofactor guanylyltransferase activity
CDG81_10145	COG0714	Associated with various cellular activities
CDG81_10160	COG1285	pathogenesis
CDG81_10165	COG0247	lactate metabolic process
CDG81_10165	COG0277	FAD linked oxidase domain protein
CDG81_10175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDG81_10225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDG81_10245	COG1830	Aldolase
CDG81_10265	COG2186	Transcriptional regulator
CDG81_10275	COG1316	TRANSCRIPTIONal
CDG81_10295	COG0542	response to heat
CDG81_10320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG81_10325	COG1366	Belongs to the anti-sigma-factor antagonist family
CDG81_10335	COG2318	DinB family
CDG81_10355	COG0477	Major facilitator Superfamily
CDG81_10365	COG0039	L-malate dehydrogenase activity
CDG81_10390	COG1643	Atp-dependent helicase
CDG81_10460	COG2367	Beta-lactamase
CDG81_10495	COG4974	Belongs to the 'phage' integrase family
CDG81_10520	COG1609	Transcriptional regulator
CDG81_10530	COG0640	Transcriptional regulator
CDG81_10545	COG1472	Belongs to the glycosyl hydrolase 3 family
CDG81_10560	COG1073	alpha beta
CDG81_10585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG81_10630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_10630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_10720	COG1309	transcriptional regulator
CDG81_10730	COG1819	glycosyl
CDG81_10740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDG81_10770	COG0406	alpha-ribazole phosphatase activity
CDG81_10775	COG1968	undecaprenyl-diphosphatase activity
CDG81_10780	COG0667	Aldo Keto reductase
CDG81_10785	COG0477	Major facilitator Superfamily
CDG81_10795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG81_10820	COG1131	(ABC) transporter
CDG81_10825	COG3559	Exporter of polyketide antibiotics
CDG81_10855	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_10905	COG0789	Transcriptional regulator
CDG81_10920	COG2814	Major facilitator Superfamily
CDG81_10925	COG1492	cobalamin metabolic process
CDG81_10930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG81_10950	COG0346	lactoylglutathione lyase activity
CDG81_10960	COG0437	4 iron, 4 sulfur cluster binding
CDG81_10965	COG3383	formate dehydrogenase (NAD+) activity
CDG81_10965	COG0243	molybdopterin cofactor binding
CDG81_10970	COG3383	formate dehydrogenase (NAD+) activity
CDG81_10970	COG0243	molybdopterin cofactor binding
CDG81_11020	COG1309	transcriptional regulator
CDG81_11025	COG0709	Synthesizes selenophosphate from selenide and ATP
CDG81_11040	COG1921	L-seryl-tRNASec selenium transferase activity
CDG81_11050	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDG81_11055	COG0542	response to heat
CDG81_11080	COG0702	epimerase
CDG81_11095	COG1278	Cold shock
CDG81_11100	COG3321	synthase
CDG81_11100	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_11100	COG0604	alcohol dehydrogenase
CDG81_11105	COG4607	ABC-type enterochelin transport system periplasmic component
CDG81_11145	COG0589	response to stress
CDG81_11155	COG0589	response to stress
CDG81_11160	COG0589	response to stress
CDG81_11165	COG0589	response to stress
CDG81_11190	COG2814	Major facilitator Superfamily
CDG81_11195	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CDG81_11235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_11240	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CDG81_11245	COG2226	methyltransferase
CDG81_11245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_11245	COG3433	isochorismatase activity
CDG81_11270	COG1228	amidohydrolase
CDG81_11275	COG3588	fructose-bisphosphate aldolase
CDG81_11295	COG0395	ABC-type sugar transport system, permease component
CDG81_11310	COG5297	Belongs to the glycosyl hydrolase family 6
CDG81_11320	COG5297	Belongs to the glycosyl hydrolase family 6
CDG81_11330	COG2223	nitrite transmembrane transporter activity
CDG81_11340	COG1940	carbohydrate kinase activity
CDG81_11345	COG1129	ABC transporter
CDG81_11350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDG81_11355	COG4213	ABC transporter substrate-binding protein
CDG81_11360	COG0673	inositol 2-dehydrogenase activity
CDG81_11370	COG2133	pyrroloquinoline quinone binding
CDG81_11385	COG1082	Xylose isomerase domain protein TIM barrel
CDG81_11395	COG0084	hydrolase, TatD family'
CDG81_11420	COG0604	alcohol dehydrogenase
CDG81_11440	COG0488	(ABC) transporter
CDG81_11470	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CDG81_11475	COG0659	secondary active sulfate transmembrane transporter activity
CDG81_11480	COG0789	Transcriptional regulator
CDG81_11500	COG1278	Cold shock
CDG81_11520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDG81_11560	COG2267	carboxylic ester hydrolase activity
CDG81_11565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_11575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_11585	COG3279	Response regulator of the LytR AlgR family
CDG81_11590	COG3275	phosphorelay sensor kinase activity
CDG81_11635	COG2205	protein histidine kinase activity
CDG81_11665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG81_11670	COG1937	Protein conserved in bacteria
CDG81_11710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDG81_11715	COG3483	tryptophan 2,3-dioxygenase activity
CDG81_11735	COG0415	Belongs to the DNA photolyase family
CDG81_11755	COG0583	DNA-binding transcription factor activity
CDG81_11810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_11820	COG0798	PFAM Bile acid sodium symporter
CDG81_11825	COG0640	Transcriptional regulator
CDG81_11870	COG1175	transmembrane transport
CDG81_11875	COG0395	ABC-type sugar transport system, permease component
CDG81_11885	COG0673	inositol 2-dehydrogenase activity
CDG81_11890	COG3842	ATPase activity
CDG81_11895	COG1609	Transcriptional regulator
CDG81_11910	COG1929	Belongs to the glycerate kinase type-1 family
CDG81_11925	COG2814	Major facilitator Superfamily
CDG81_11930	COG1609	Transcriptional regulator
CDG81_11940	COG3347	Dehydrogenase
CDG81_11940	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_11945	COG1070	Carbohydrate kinase
CDG81_11950	COG0247	lactate metabolic process
CDG81_11960	COG1556	Lactate utilization protein
CDG81_11975	COG0107	imidazoleglycerol-phosphate synthase activity
CDG81_12025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDG81_12035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG81_12040	COG1121	(ABC) transporter
CDG81_12050	COG2860	membrane
CDG81_12060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CDG81_12060	COG2308	Evidence 4 Homologs of previously reported genes of
CDG81_12095	COG0463	Glycosyl transferase, family 2
CDG81_12100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG81_12115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_12145	COG0667	Aldo Keto reductase
CDG81_12175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG81_12190	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDG81_12190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDG81_12210	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CDG81_12215	COG0517	IMP dehydrogenase activity
CDG81_12215	COG0516	GMP reductase activity
CDG81_12220	COG0302	gtp cyclohydrolase
CDG81_12225	COG0602	queuosine metabolic process
CDG81_12230	COG0720	synthase
CDG81_12265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_12270	COG1309	transcriptional regulator
CDG81_12290	COG0515	serine threonine protein kinase
CDG81_12290	COG2815	serine threonine protein kinase
CDG81_12425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_12430	COG1940	carbohydrate kinase activity
CDG81_12440	COG0726	polysaccharide deacetylase
CDG81_12450	COG3842	ATPase activity
CDG81_12455	COG0366	Alpha amylase catalytic
CDG81_12490	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDG81_12545	COG2608	mercury ion transmembrane transporter activity
CDG81_12550	COG2132	Multicopper oxidase
CDG81_12555	COG1937	Protein conserved in bacteria
CDG81_12595	COG1959	2 iron, 2 sulfur cluster binding
CDG81_12605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG81_12625	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDG81_12630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_12640	COG5522	Integral membrane protein (intg_mem_TP0381)
CDG81_12665	COG0702	epimerase
CDG81_12680	COG0477	Major facilitator Superfamily
CDG81_12690	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_12695	COG2146	nitrite reductase [NAD(P)H] activity
CDG81_12695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_12700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_12705	COG0243	molybdopterin cofactor binding
CDG81_12710	COG1169	isochorismate synthase
CDG81_12715	COG1902	pentaerythritol trinitrate reductase activity
CDG81_12730	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDG81_12735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_12745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG81_12785	COG0009	L-threonylcarbamoyladenylate synthase
CDG81_12815	COG3257	ureidoglycine aminohydrolase activity
CDG81_12830	COG1609	Transcriptional regulator
CDG81_12845	COG4608	Belongs to the ABC transporter superfamily
CDG81_12850	COG0444	Belongs to the ABC transporter superfamily
CDG81_12860	COG0601	transmembrane transport
CDG81_12865	COG0747	negative chemotaxis
CDG81_12870	COG3345	alpha-galactosidase
CDG81_12890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG81_12890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG81_12900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG81_12950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_12965	COG0326	Molecular chaperone. Has ATPase activity
CDG81_12995	COG0006	proline dipeptidase activity
CDG81_13060	COG1857	crispr-associated protein
CDG81_13100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_13105	COG1120	ATPase activity
CDG81_13130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG81_13135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG81_13145	COG2124	cytochrome p450
CDG81_13155	COG0667	Aldo Keto reductase
CDG81_13160	COG1819	glycosyl
CDG81_13165	COG2124	cytochrome p450
CDG81_13210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG81_13220	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDG81_13225	COG2124	cytochrome p450
CDG81_13255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDG81_13255	COG2070	2-Nitropropane dioxygenase
CDG81_13320	COG0367	asparagine synthase
CDG81_13335	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG81_13435	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDG81_13445	COG1799	cell septum assembly
CDG81_13485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDG81_13505	COG2226	methyltransferase
CDG81_13525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDG81_13530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG81_13645	COG5285	phytanoyl-CoA dioxygenase
CDG81_13675	COG1607	acyl-coa hydrolase
CDG81_13680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_13690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG81_13700	COG2124	cytochrome p450
CDG81_13715	COG1917	Cupin 2, conserved barrel domain protein
CDG81_13735	COG0527	aspartate kinase activity
CDG81_13800	COG5650	phosphatidylinositol metabolic process
CDG81_13955	COG0596	Alpha beta hydrolase
CDG81_13985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG81_14010	COG2270	Major facilitator Superfamily
CDG81_14020	COG0463	Glycosyl transferase, family 2
CDG81_14030	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CDG81_14035	COG3030	protein affecting phage T7 exclusion by the F plasmid
CDG81_14045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG81_14085	COG4552	Acetyltransferase involved in intracellular survival and related
CDG81_14125	COG0154	amidase activity
CDG81_14130	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CDG81_14135	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CDG81_14140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CDG81_14160	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_14190	COG1222	aaa ATPase
CDG81_14220	COG1994	Peptidase M50
CDG81_14220	COG0517	IMP dehydrogenase activity
CDG81_14240	COG0140	phosphoribosyl-ATP diphosphatase activity
CDG81_14270	COG2018	Roadblock/LC7 domain
CDG81_14280	COG0215	cysteine-tRNA ligase activity
CDG81_14300	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDG81_14315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_14320	COG0601	transmembrane transport
CDG81_14330	COG2362	D-Aminopeptidase
CDG81_14355	COG0488	(ABC) transporter
CDG81_14370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_14385	COG2151	metal-sulfur cluster biosynthetic enzyme
CDG81_14400	COG0396	ATPase activity
CDG81_14445	COG1510	regulation of RNA biosynthetic process
CDG81_14475	COG0586	Pfam SNARE associated Golgi protein
CDG81_14490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG81_14495	COG0166	Belongs to the GPI family
CDG81_14510	COG0363	glucosamine-6-phosphate deaminase activity
CDG81_14520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG81_14535	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CDG81_14610	COG0375	protein maturation
CDG81_14625	COG0298	carbon dioxide binding
CDG81_14655	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CDG81_14665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDG81_14675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDG81_14695	COG0210	DNA helicase
CDG81_14700	COG0515	serine threonine protein kinase
CDG81_14700	COG2815	serine threonine protein kinase
CDG81_14795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDG81_14845	COG0149	triose-phosphate isomerase activity
CDG81_14850	COG0126	phosphoglycerate kinase activity
CDG81_14860	COG1481	regulation of sporulation
CDG81_14865	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CDG81_14870	COG1660	Displays ATPase and GTPase activities
CDG81_14875	COG0322	excinuclease ABC activity
CDG81_14885	COG0167	dihydroorotate dehydrogenase activity
CDG81_14895	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDG81_14900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_14900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_14925	COG1113	amino acid transport
CDG81_14930	COG0037	tRNA processing
CDG81_14930	COG0590	tRNA wobble adenosine to inosine editing
CDG81_14945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDG81_14970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG81_14980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG81_14990	COG1758	RNA polymerase activity
CDG81_14995	COG0194	GDP metabolic process
CDG81_15005	COG0284	orotidine-5'-phosphate decarboxylase activity
CDG81_15015	COG0505	Belongs to the CarA family
CDG81_15030	COG0540	Belongs to the ATCase OTCase family
CDG81_15045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDG81_15050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG81_15075	COG1070	Carbohydrate kinase
CDG81_15085	COG1349	DNA-binding transcription factor activity
CDG81_15090	COG1063	alcohol dehydrogenase
CDG81_15095	COG0395	ABC-type sugar transport system, permease component
CDG81_15100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDG81_15105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDG81_15110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDG81_15115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDG81_15125	COG2190	(PTS) system
CDG81_15130	COG2190	(PTS) system
CDG81_15130	COG1263	PTS System
CDG81_15130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDG81_15135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDG81_15135	COG1263	PTS System
CDG81_15140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDG81_15145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDG81_15160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDG81_15205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG81_15220	COG0076	glutamate decarboxylase activity
CDG81_15270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG81_15275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG81_15280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDG81_15295	COG2255	four-way junction helicase activity
CDG81_15300	COG0632	four-way junction helicase activity
CDG81_15305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDG81_15320	COG0217	transcriptional regulatory protein
CDG81_15325	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CDG81_15330	COG1113	amino acid transport
CDG81_15345	COG1396	sequence-specific DNA binding
CDG81_15350	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CDG81_15405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_15420	COG2353	YceI-like domain
CDG81_15430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDG81_15455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG81_15455	COG1017	nitric oxide dioxygenase activity
CDG81_15460	COG1959	2 iron, 2 sulfur cluster binding
CDG81_15465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDG81_15470	COG0277	FAD linked oxidase domain protein
CDG81_15475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDG81_15490	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_15495	COG0506	proline dehydrogenase activity
CDG81_15540	COG1950	PFAM Membrane protein of
CDG81_15545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_15550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG81_15565	COG0673	inositol 2-dehydrogenase activity
CDG81_15570	COG2197	response regulator
CDG81_15575	COG4585	Histidine kinase
CDG81_15600	COG1960	acyl-CoA dehydrogenase activity
CDG81_15605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG81_15610	COG1802	Transcriptional regulator
CDG81_15640	COG0693	protein deglycase activity
CDG81_15650	COG0579	oxidoreductase
CDG81_15665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG81_15725	COG5006	permease, DMT superfamily
CDG81_15740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG81_15760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDG81_15775	COG2197	response regulator
CDG81_15780	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CDG81_15785	COG0183	Belongs to the thiolase family
CDG81_15790	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_15790	COG1024	Enoyl-CoA hydratase
CDG81_15800	COG2205	protein histidine kinase activity
CDG81_15805	COG0745	RESPONSE REGULATOR receiver
CDG81_15810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDG81_15815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG81_15820	COG0531	amino acid
CDG81_15825	COG0569	domain protein
CDG81_15850	COG0756	dUTP diphosphatase activity
CDG81_15915	COG1490	D-aminoacyl-tRNA deacylase activity
CDG81_15945	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDG81_15955	COG1321	iron dependent repressor
CDG81_15960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CDG81_15965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG81_15975	COG2936	dipeptidyl-peptidase activity
CDG81_15995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDG81_16015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG81_16025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDG81_16030	COG1196	nuclear chromosome segregation
CDG81_16040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDG81_16045	COG1126	abc transporter atp-binding protein
CDG81_16050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDG81_16055	COG0765	amino acid transport
CDG81_16060	COG0765	amino acid transport
CDG81_16090	COG2137	regulation of response to DNA damage stimulus
CDG81_16095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDG81_16110	COG1201	RNA secondary structure unwinding
CDG81_16130	COG0142	geranyltranstransferase activity
CDG81_16140	COG2815	serine threonine protein kinase
CDG81_16140	COG0515	serine threonine protein kinase
CDG81_16145	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDG81_16175	COG0003	Pfam Anion-transporting ATPase
CDG81_16245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG81_16270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG81_16285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDG81_16300	COG0667	Aldo Keto reductase
CDG81_16330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDG81_16350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG81_16360	COG1090	epimerase
CDG81_16365	COG0321	lipoyl(octanoyl) transferase activity
CDG81_16390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG81_16430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG81_16435	COG0519	Catalyzes the synthesis of GMP from XMP
CDG81_16435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG81_16475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG81_16490	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDG81_16495	COG0019	diaminopimelate decarboxylase activity
CDG81_16500	COG3835	regulator
CDG81_16520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDG81_16525	COG0590	tRNA wobble adenosine to inosine editing
CDG81_16530	COG2252	PERMEase
CDG81_16565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_16570	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDG81_16600	COG0028	Belongs to the TPP enzyme family
CDG81_16635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDG81_16640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG81_16650	COG1234	tRNA 3'-trailer cleavage
CDG81_16655	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG81_16690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG81_16695	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDG81_16700	COG1335	isochorismatase
CDG81_16715	COG1268	BioY protein
CDG81_16720	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_16725	COG0183	Belongs to the thiolase family
CDG81_16730	COG1122	ATPase activity
CDG81_16760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG81_16805	COG0667	Aldo Keto reductase
CDG81_16815	COG1984	allophanate hydrolase subunit 2
CDG81_16820	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDG81_16825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDG81_16855	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_16865	COG0367	asparagine synthase
CDG81_16890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG81_16910	COG0583	DNA-binding transcription factor activity
CDG81_16915	COG2814	Major facilitator Superfamily
CDG81_16920	COG2226	methyltransferase
CDG81_17020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDG81_17030	COG0823	Involved in the tonB-independent uptake of proteins
CDG81_17035	COG1357	PFAM Pentapeptide repeats (8 copies)
CDG81_17050	COG3693	PFAM glycoside hydrolase, family 10
CDG81_17050	COG3509	depolymerase
CDG81_17085	COG2197	response regulator
CDG81_17100	COG2226	methyltransferase
CDG81_17150	COG0477	Major facilitator Superfamily
CDG81_17165	COG1122	ATPase activity
CDG81_17170	COG2072	flavoprotein involved in K transport
CDG81_17180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG81_17195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDG81_17200	COG2177	Part of the ABC transporter FtsEX involved in
CDG81_17205	COG2884	Cell division ATP-binding protein ftsE
CDG81_17210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDG81_17235	COG1615	UPF0182 protein
CDG81_17260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG81_17290	COG0612	Peptidase, M16
CDG81_17320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG81_17390	COG2267	carboxylic ester hydrolase activity
CDG81_17420	COG0513	Belongs to the DEAD box helicase family
CDG81_17440	COG0613	PHP domain protein
CDG81_17455	COG0598	Magnesium transport protein CorA
CDG81_17475	COG1266	CAAX protease self-immunity
CDG81_17480	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG81_17505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG81_17585	COG2301	Belongs to the HpcH HpaI aldolase family
CDG81_17590	COG2239	Acts as a magnesium transporter
CDG81_17610	COG1595	DNA-templated transcription, initiation
CDG81_17615	COG5662	AntiSigma factor
CDG81_17620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG81_17625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDG81_17640	COG1024	Enoyl-CoA hydratase
CDG81_17645	COG2818	Glycosylase
CDG81_17675	COG1611	Belongs to the LOG family
CDG81_17680	COG1611	Belongs to the LOG family
CDG81_17685	COG0330	HflC and HflK could
CDG81_17695	COG2171	N-acyltransferase activity
CDG81_17715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_17740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_17765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_17775	COG0747	negative chemotaxis
CDG81_17795	COG0494	nUDIX hydrolase
CDG81_17800	COG5002	protein histidine kinase activity
CDG81_17800	COG3850	Histidine kinase
CDG81_17815	COG1131	(ABC) transporter
CDG81_17835	COG3842	ATPase activity
CDG81_17855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CDG81_17860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDG81_17865	COG0156	8-amino-7-oxononanoate synthase activity
CDG81_17920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDG81_17925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDG81_17930	COG2080	2 iron, 2 sulfur cluster binding
CDG81_17935	COG3708	Transcriptional regulator
CDG81_17935	COG2207	Transcriptional regulator
CDG81_18005	COG1518	maintenance of DNA repeat elements
CDG81_18010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG81_18080	COG0012	GTP binding
CDG81_18100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG81_18100	COG2169	Transcriptional regulator
CDG81_18110	COG0419	ATPase involved in DNA repair
CDG81_18115	COG0420	3'-5' exonuclease activity
CDG81_18125	COG1070	Carbohydrate kinase
CDG81_18135	COG1609	Transcriptional regulator
CDG81_18150	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDG81_18155	COG1129	ABC transporter
CDG81_18165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDG81_18175	COG1570	exodeoxyribonuclease VII activity
CDG81_18185	COG1722	exodeoxyribonuclease VII activity
CDG81_18200	COG0492	ferredoxin-NADP+ reductase activity
CDG81_18205	COG0114	fumarate hydratase activity
CDG81_18210	COG0745	RESPONSE REGULATOR receiver
CDG81_18210	COG3706	GGDEF domain
CDG81_18220	COG0516	GMP reductase activity
CDG81_18220	COG0517	IMP dehydrogenase activity
CDG81_18245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDG81_18250	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_18270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_18285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG81_18290	COG2423	ornithine cyclodeaminase activity
CDG81_18300	COG2197	response regulator
CDG81_18325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG81_18330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG81_18345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDG81_18355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG81_18370	COG2986	histidine ammonia-lyase
CDG81_18380	COG0583	DNA-binding transcription factor activity
CDG81_18385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG81_18405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CDG81_18440	COG1331	Highly conserved protein containing a thioredoxin domain
CDG81_18450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG81_18460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_18470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG81_18480	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CDG81_18510	COG0183	Belongs to the thiolase family
CDG81_18535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_18550	COG1252	NADH dehydrogenase
CDG81_18565	COG4608	Belongs to the ABC transporter superfamily
CDG81_18575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_18580	COG0601	transmembrane transport
CDG81_18585	COG4166	transmembrane transport
CDG81_18605	COG1960	acyl-CoA dehydrogenase activity
CDG81_18620	COG0148	phosphopyruvate hydratase activity
CDG81_18640	COG3956	TIGRFAM MazG family protein
CDG81_18755	COG0277	FAD linked oxidase domain protein
CDG81_18805	COG2133	pyrroloquinoline quinone binding
CDG81_18815	COG1366	Belongs to the anti-sigma-factor antagonist family
CDG81_18835	COG3706	GGDEF domain
CDG81_18855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDG81_18860	COG0193	aminoacyl-tRNA hydrolase activity
CDG81_18865	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_18890	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_18895	COG0488	(ABC) transporter
CDG81_18900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDG81_18905	COG1464	Belongs to the NlpA lipoprotein family
CDG81_18910	COG2011	ABC-type metal ion transport system permease component
CDG81_18915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG81_18920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG81_18925	COG3583	domain protein
CDG81_18930	COG1652	LysM domain
CDG81_18935	COG0084	hydrolase, TatD family'
CDG81_18940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG81_18945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDG81_18950	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_18955	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_19015	COG2009	succinate dehydrogenase
CDG81_19030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG81_19040	COG1686	Belongs to the peptidase S11 family
CDG81_19045	COG1295	ribonuclease BN
CDG81_19050	COG0180	Tryptophanyl-tRNA synthetase
CDG81_19070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDG81_19075	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CDG81_19080	COG1404	Belongs to the peptidase S8 family
CDG81_19110	COG0708	Exodeoxyribonuclease III
CDG81_19120	COG2409	Drug exporters of the RND superfamily
CDG81_19145	COG2072	flavoprotein involved in K transport
CDG81_19155	COG1757	Na H antiporter
CDG81_19225	COG2409	Drug exporters of the RND superfamily
CDG81_19265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDG81_19315	COG0045	succinate-CoA ligase (ADP-forming) activity
CDG81_19325	COG0739	heme binding
CDG81_19335	COG1131	(ABC) transporter
CDG81_19340	COG3559	Exporter of polyketide antibiotics
CDG81_19355	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_19385	COG0515	serine threonine protein kinase
CDG81_19390	COG0583	DNA-binding transcription factor activity
CDG81_19395	COG0697	spore germination
CDG81_19410	COG2197	response regulator
CDG81_19430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG81_19430	COG0519	Catalyzes the synthesis of GMP from XMP
CDG81_19440	COG0516	GMP reductase activity
CDG81_19480	COG0459	protein refolding
CDG81_19490	COG3540	Alkaline phosphatase
CDG81_19495	COG3540	Alkaline phosphatase
CDG81_19515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDG81_19520	COG0456	acetyltransferase
CDG81_19525	COG0456	acetyltransferase
CDG81_19525	COG1214	PFAM Peptidase M22, glycoprotease
CDG81_19530	COG3250	beta-galactosidase activity
CDG81_19535	COG4266	Belongs to the allantoicase family
CDG81_19540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDG81_19545	COG1929	Belongs to the glycerate kinase type-1 family
CDG81_19550	COG3960	tartronate-semialdehyde synthase activity
CDG81_19555	COG2084	Dehydrogenase
CDG81_19565	COG3622	Belongs to the hyi family
CDG81_19600	COG2233	PERMEase
CDG81_19630	COG1414	Transcriptional regulator
CDG81_19715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG81_19725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG81_19765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG81_19770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG81_19775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDG81_19785	COG4842	Belongs to the WXG100 family
CDG81_19795	COG0443	Heat shock 70 kDa protein
CDG81_19800	COG1674	ftsk spoiiie
CDG81_19810	COG1404	Belongs to the peptidase S8 family
CDG81_19835	COG0203	ribosomal protein L17
CDG81_19840	COG0202	RNA polymerase activity
CDG81_19845	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDG81_19850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDG81_19855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDG81_19860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDG81_19865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDG81_19870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG81_19890	COG0200	Binds to the 23S rRNA
CDG81_19895	COG1841	ribosomal large subunit assembly
CDG81_19900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG81_19905	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDG81_19910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDG81_19915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG81_19920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDG81_19925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDG81_19930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDG81_19935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDG81_19940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDG81_19945	COG0255	Belongs to the universal ribosomal protein uL29 family
CDG81_19950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDG81_19955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDG81_19960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDG81_19965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG81_19970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDG81_19975	COG0089	rRNA binding
CDG81_19980	COG0088	Forms part of the polypeptide exit tunnel
CDG81_19985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDG81_19995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDG81_20000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDG81_20005	COG0049	tRNA binding
CDG81_20010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDG81_20020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDG81_20025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_20035	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDG81_20040	COG0085	RNA polymerase activity
CDG81_20100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_20145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG81_20155	COG1127	ABC transporter
CDG81_20210	COG0222	ribosome binding
CDG81_20215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDG81_20230	COG0081	regulation of translation
CDG81_20235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDG81_20255	COG0436	Aminotransferase
CDG81_20265	COG2030	dehydratase
CDG81_20270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDG81_20320	COG2018	Roadblock/LC7 domain
CDG81_20330	COG3162	membrane
CDG81_20335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_20340	COG0596	Alpha beta hydrolase
CDG81_20360	COG4115	mRNA cleavage
CDG81_20365	COG2161	toxin-antitoxin pair type II binding
CDG81_20375	COG1666	GTP binding
CDG81_20385	COG0501	Belongs to the peptidase M48B family
CDG81_20395	COG1834	amidinotransferase
CDG81_20400	COG1522	sequence-specific DNA binding
CDG81_20410	COG0142	geranyltranstransferase activity
CDG81_20415	COG1007	ATP synthesis coupled electron transport
CDG81_20430	COG0713	ATP synthesis coupled electron transport
CDG81_20440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG81_20445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDG81_20450	COG1034	ATP synthesis coupled electron transport
CDG81_20465	COG0649	NAD binding
CDG81_20470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG81_20475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG81_20490	COG2226	methyltransferase
CDG81_20525	COG0308	aminopeptidase N
CDG81_20540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDG81_20545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CDG81_20585	COG0477	Major facilitator Superfamily
CDG81_20595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG81_20610	COG2814	Major facilitator Superfamily
CDG81_20615	COG0656	L-ascorbic acid biosynthetic process
CDG81_20625	COG0435	Glutathione S-transferase
CDG81_20630	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDG81_20635	COG0159	tryptophan synthase activity
CDG81_20640	COG0133	tryptophan synthase activity
CDG81_20645	COG0134	indole-3-glycerol-phosphate synthase activity
CDG81_20650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG81_20655	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG81_20660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDG81_20665	COG2124	cytochrome p450
CDG81_20670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_20675	COG2197	response regulator
CDG81_20700	COG4585	Histidine kinase
CDG81_20730	COG1959	2 iron, 2 sulfur cluster binding
CDG81_20735	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_20815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDG81_20825	COG0785	Cytochrome C biogenesis protein
CDG81_20830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDG81_20835	COG0406	alpha-ribazole phosphatase activity
CDG81_20840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDG81_20880	COG0181	hydroxymethylbilane synthase activity
CDG81_20885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CDG81_20890	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDG81_20905	COG0560	Phosphoserine phosphatase
CDG81_20925	COG5001	Diguanylate cyclase
CDG81_20955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDG81_20980	COG5002	protein histidine kinase activity
CDG81_20995	COG0438	transferase activity, transferring glycosyl groups
CDG81_21015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDG81_21065	COG2733	membrane
CDG81_21085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_21100	COG0598	Magnesium transport protein CorA
CDG81_21155	COG2608	mercury ion transmembrane transporter activity
CDG81_21180	COG1960	acyl-CoA dehydrogenase activity
CDG81_21190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_21220	COG0656	L-ascorbic acid biosynthetic process
CDG81_21225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_21235	COG1739	Uncharacterized protein family UPF0029
CDG81_21255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG81_21260	COG2151	metal-sulfur cluster biosynthetic enzyme
CDG81_21265	COG3396	Phenylacetate-CoA oxygenase
CDG81_21270	COG3460	Phenylacetate-CoA oxygenase
CDG81_21275	COG3396	Phenylacetate-CoA oxygenase
CDG81_21280	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_21280	COG2030	dehydratase
CDG81_21295	COG1309	transcriptional regulator
CDG81_21300	COG0531	amino acid
CDG81_21305	COG0531	amino acid
CDG81_21310	COG1597	lipid kinase activity
CDG81_21320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_21325	COG3573	Dehydrogenase
CDG81_21345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDG81_21365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG81_21370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDG81_21385	COG0367	asparagine synthase
CDG81_21395	COG1309	transcriptional regulator
CDG81_21405	COG2814	Major facilitator Superfamily
CDG81_21410	COG1942	4-Oxalocrotonate Tautomerase
CDG81_21435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_21450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG81_21485	COG0673	inositol 2-dehydrogenase activity
CDG81_21500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_21520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_21560	COG0494	nUDIX hydrolase
CDG81_21595	COG0745	RESPONSE REGULATOR receiver
CDG81_21595	COG3706	GGDEF domain
CDG81_21605	COG0704	Plays a role in the regulation of phosphate uptake
CDG81_21615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG81_21620	COG0581	inorganic phosphate transmembrane transporter activity
CDG81_21635	COG0456	acetyltransferase
CDG81_21685	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CDG81_21705	COG0354	folic acid binding
CDG81_21740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDG81_21770	COG3387	PFAM Glycoside hydrolase 15-related
CDG81_21775	COG1063	alcohol dehydrogenase
CDG81_21825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG81_21840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDG81_21850	COG0360	Binds together with S18 to 16S ribosomal RNA
CDG81_21860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDG81_21865	COG0359	binds to the 23S rRNA
CDG81_21920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG81_21925	COG2814	Major facilitator Superfamily
CDG81_21935	COG4221	oxidoreductase activity
CDG81_21940	COG0402	S-adenosylhomocysteine deaminase activity
CDG81_21950	COG2197	response regulator
CDG81_21955	COG4585	Histidine kinase
CDG81_21960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG81_21975	COG1131	(ABC) transporter
CDG81_21980	COG0561	phosphatase activity
CDG81_21990	COG2197	response regulator
CDG81_21995	COG4585	Histidine kinase
CDG81_22020	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CDG81_22115	COG2375	cellular response to nickel ion
CDG81_22125	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CDG81_22140	COG0765	amino acid transport
CDG81_22145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDG81_22150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG81_22170	COG0022	dehydrogenase e1 component
CDG81_22175	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDG81_22200	COG1309	transcriptional regulator
CDG81_22215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDG81_22225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDG81_22240	COG2076	Multidrug Resistance protein
CDG81_22250	COG1595	DNA-templated transcription, initiation
CDG81_22255	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CDG81_22270	COG0151	Belongs to the GarS family
CDG81_22280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG81_22295	COG4129	membrane
CDG81_22320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDG81_22335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_22360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG81_22360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG81_22405	COG2814	Major facilitator Superfamily
CDG81_22445	COG0542	response to heat
CDG81_22455	COG2353	YceI-like domain
CDG81_22460	COG0477	Major facilitator Superfamily
CDG81_22515	COG1295	ribonuclease BN
CDG81_22545	COG0789	Transcriptional regulator
CDG81_22550	COG0484	heat shock protein binding
CDG81_22555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDG81_22560	COG0443	Heat shock 70 kDa protein
CDG81_22570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG81_22575	COG3226	Transcriptional regulator
CDG81_22580	COG2076	Multidrug Resistance protein
CDG81_22640	COG0477	Major facilitator Superfamily
CDG81_22645	COG0717	Belongs to the dCTP deaminase family
CDG81_22655	COG0494	nUDIX hydrolase
CDG81_22660	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDG81_22710	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_22730	COG0385	Bile acid
CDG81_22760	COG0668	transmembrane transport
CDG81_22765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG81_22770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG81_22790	COG0789	Transcriptional regulator
CDG81_22805	COG1960	acyl-CoA dehydrogenase activity
CDG81_22820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDG81_22850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG81_22860	COG1309	transcriptional regulator
CDG81_22865	COG0745	RESPONSE REGULATOR receiver
CDG81_22890	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG81_22895	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG81_22900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG81_22940	COG3706	GGDEF domain
CDG81_22950	COG2197	response regulator
CDG81_22960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDG81_23010	COG0495	leucyl-tRNA aminoacylation
CDG81_23020	COG1678	Uncharacterized ACR, COG1678
CDG81_23030	COG0617	tRNA 3'-terminal CCA addition
CDG81_23055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG81_23055	COG0515	serine threonine protein kinase
CDG81_23060	COG1595	DNA-templated transcription, initiation
CDG81_23075	COG0492	ferredoxin-NADP+ reductase activity
CDG81_23075	COG3118	belongs to the thioredoxin family
CDG81_23080	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_23080	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDG81_23090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_23095	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDG81_23105	COG1192	Involved in chromosome partitioning
CDG81_23110	COG0357	Ribosomal RNA small subunit methyltransferase G
CDG81_23125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDG81_23130	COG0594	ribonuclease P activity
CDG81_23135	COG0230	Belongs to the bacterial ribosomal protein bL34 family