locus-tag	class	description
KCV87_00020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCV87_00025	COG0745	RESPONSE REGULATOR receiver
KCV87_00030	COG0596	Alpha beta hydrolase
KCV87_00035	COG4335	DNA alkylation repair
KCV87_00050	COG0673	inositol 2-dehydrogenase activity
KCV87_00110	COG2197	response regulator
KCV87_00115	COG3851	Histidine kinase
KCV87_00135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KCV87_00140	COG0596	Alpha beta hydrolase
KCV87_00165	COG0435	Glutathione S-transferase
KCV87_00170	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_00180	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_00200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCV87_00215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCV87_00220	COG3226	Transcriptional regulator
KCV87_00235	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_00240	COG1309	transcriptional regulator
KCV87_00245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCV87_00295	COG1064	alcohol dehydrogenase
KCV87_00325	COG3509	depolymerase
KCV87_00375	COG1309	transcriptional regulator
KCV87_00385	COG2197	response regulator
KCV87_00430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCV87_00465	COG3940	Belongs to the glycosyl hydrolase 43 family
KCV87_00475	COG2192	nodulation
KCV87_00520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_00525	COG1120	ATPase activity
KCV87_00540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_00580	COG0604	alcohol dehydrogenase
KCV87_00580	COG4221	oxidoreductase activity
KCV87_00580	COG3321	synthase
KCV87_00580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_00595	COG0583	DNA-binding transcription factor activity
KCV87_00600	COG0702	epimerase
KCV87_00630	COG2175	clavaminate synthase activity
KCV87_00635	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_00635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_00635	COG3321	synthase
KCV87_00635	COG4221	oxidoreductase activity
KCV87_00785	COG0582	viral genome integration into host DNA
KCV87_00820	COG0134	indole-3-glycerol-phosphate synthase activity
KCV87_00860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCV87_00870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCV87_00880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KCV87_00890	COG0438	transferase activity, transferring glycosyl groups
KCV87_00915	COG0720	synthase
KCV87_00920	COG0602	queuosine metabolic process
KCV87_00960	COG0582	viral genome integration into host DNA
KCV87_00975	COG0745	RESPONSE REGULATOR receiver
KCV87_00985	COG2755	lipolytic protein G-D-S-L family
KCV87_01045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCV87_01050	COG2814	Major facilitator Superfamily
KCV87_01075	COG0596	Alpha beta hydrolase
KCV87_01085	COG3537	Alpha-1,2-mannosidase
KCV87_01100	COG1309	transcriptional regulator
KCV87_01130	COG0673	inositol 2-dehydrogenase activity
KCV87_01140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCV87_01165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCV87_01180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCV87_01185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KCV87_01195	COG1021	2,3-dihydroxybenzoate-AMP ligase
KCV87_01200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCV87_01235	COG0667	Aldo Keto reductase
KCV87_01260	COG4106	trans-aconitate 2-methyltransferase activity
KCV87_01280	COG0142	geranyltranstransferase activity
KCV87_01305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KCV87_01305	COG1017	nitric oxide dioxygenase activity
KCV87_01310	COG1959	2 iron, 2 sulfur cluster binding
KCV87_01325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCV87_01330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCV87_01350	COG3345	alpha-galactosidase
KCV87_01380	COG4257	antibiotic catabolic process
KCV87_01435	COG3210	domain, Protein
KCV87_01475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCV87_01500	COG0789	Transcriptional regulator
KCV87_01580	COG2072	flavoprotein involved in K transport
KCV87_01595	COG1366	Belongs to the anti-sigma-factor antagonist family
KCV87_01600	COG1366	Belongs to the anti-sigma-factor antagonist family
KCV87_01605	COG2172	sigma factor antagonist activity
KCV87_01615	COG0784	Response regulator, receiver
KCV87_01615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCV87_01615	COG2198	Histidine kinase
KCV87_01615	COG2205	protein histidine kinase activity
KCV87_01630	COG3903	Transcriptional regulator
KCV87_01630	COG3629	intracellular signal transduction
KCV87_01635	COG1366	Belongs to the anti-sigma-factor antagonist family
KCV87_01635	COG2172	sigma factor antagonist activity
KCV87_01635	COG2208	phosphoserine phosphatase activity
KCV87_01640	COG0387	Pfam Sodium calcium exchanger
KCV87_01655	COG1349	DNA-binding transcription factor activity
KCV87_01660	COG0235	Class ii aldolase
KCV87_01665	COG3395	kinase activity
KCV87_01695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCV87_01740	COG3030	protein affecting phage T7 exclusion by the F plasmid
KCV87_01760	COG1309	transcriptional regulator
KCV87_01770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_01790	COG3290	protein histidine kinase activity
KCV87_01840	COG1132	(ABC) transporter
KCV87_01900	COG2226	methyltransferase
KCV87_01930	COG0110	maltose O-acetyltransferase activity
KCV87_01965	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_01990	COG1136	(ABC) transporter
KCV87_02040	COG1132	(ABC) transporter
KCV87_02055	COG2124	cytochrome p450
KCV87_02070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCV87_02075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCV87_02080	COG2508	Transcriptional regulator
KCV87_02080	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCV87_02120	COG0310	cobalt ion transport
KCV87_02150	COG0604	alcohol dehydrogenase
KCV87_02150	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_02150	COG3321	synthase
KCV87_02155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCV87_02160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_02185	COG2124	cytochrome p450
KCV87_02195	COG2197	response regulator
KCV87_02210	COG3629	intracellular signal transduction
KCV87_02210	COG3903	Transcriptional regulator
KCV87_02220	COG3507	Belongs to the glycosyl hydrolase 43 family
KCV87_02225	COG4552	Acetyltransferase involved in intracellular survival and related
KCV87_02245	COG1309	transcriptional regulator
KCV87_02250	COG1404	Belongs to the peptidase S8 family
KCV87_02265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_02270	COG1316	TRANSCRIPTIONal
KCV87_02300	COG0438	transferase activity, transferring glycosyl groups
KCV87_02300	COG1216	Glycosyl transferase, family 2
KCV87_02330	COG2814	Major facilitator Superfamily
KCV87_02385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCV87_02395	COG1414	Transcriptional regulator
KCV87_02400	COG2909	trisaccharide binding
KCV87_02410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCV87_02450	COG0667	Aldo Keto reductase
KCV87_02455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_02460	COG1968	undecaprenyl-diphosphatase activity
KCV87_02480	COG1643	Atp-dependent helicase
KCV87_02490	COG2130	NADP-dependent
KCV87_02515	COG1846	Transcriptional regulator
KCV87_02530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCV87_02540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KCV87_02550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCV87_02560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KCV87_02595	COG2755	lipolytic protein G-D-S-L family
KCV87_02635	COG0667	Aldo Keto reductase
KCV87_02700	COG4974	Belongs to the 'phage' integrase family
KCV87_02705	COG0395	ABC-type sugar transport system, permease component
KCV87_02725	COG1609	Transcriptional regulator
KCV87_02735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCV87_02740	COG2362	D-Aminopeptidase
KCV87_02745	COG0747	negative chemotaxis
KCV87_02755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCV87_02765	COG1960	acyl-CoA dehydrogenase activity
KCV87_02775	COG1011	Hydrolase
KCV87_02800	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_02805	COG1619	proteins homologs of microcin C7 resistance protein MccF
KCV87_02845	COG2176	DNA-directed DNA polymerase activity
KCV87_02845	COG5002	protein histidine kinase activity
KCV87_02855	COG0494	nUDIX hydrolase
KCV87_02860	COG1349	DNA-binding transcription factor activity
KCV87_02865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCV87_02885	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_02945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCV87_02950	COG0798	PFAM Bile acid sodium symporter
KCV87_02955	COG0640	Transcriptional regulator
KCV87_02985	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KCV87_03000	COG3706	GGDEF domain
KCV87_03015	COG2270	Major facilitator Superfamily
KCV87_03030	COG1435	thymidine kinase activity
KCV87_03060	COG0463	Glycosyl transferase, family 2
KCV87_03080	COG1607	acyl-coa hydrolase
KCV87_03085	COG1228	amidohydrolase
KCV87_03095	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KCV87_03100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCV87_03135	COG2249	NAD(P)H dehydrogenase (quinone) activity
KCV87_03160	COG1233	COG1233 Phytoene dehydrogenase and related
KCV87_03175	COG0583	DNA-binding transcription factor activity
KCV87_03195	COG0028	Belongs to the TPP enzyme family
KCV87_03225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCV87_03230	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KCV87_03245	COG0667	Aldo Keto reductase
KCV87_03265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCV87_03280	COG1064	alcohol dehydrogenase
KCV87_03295	COG2197	response regulator
KCV87_03310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCV87_03320	COG2261	transglycosylase associated protein
KCV87_03355	COG2267	carboxylic ester hydrolase activity
KCV87_03380	COG1733	regulation of RNA biosynthetic process
KCV87_03390	COG1609	Transcriptional regulator
KCV87_03415	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_03480	COG0714	Associated with various cellular activities
KCV87_03495	COG1073	alpha beta
KCV87_03510	COG4585	Histidine kinase
KCV87_03515	COG2197	response regulator
KCV87_03530	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_03550	COG1335	isochorismatase
KCV87_03560	COG0454	-acetyltransferase
KCV87_03560	COG0456	acetyltransferase
KCV87_03565	COG1609	Transcriptional regulator
KCV87_03580	COG3509	depolymerase
KCV87_03580	COG3693	PFAM glycoside hydrolase, family 10
KCV87_03615	COG0604	alcohol dehydrogenase
KCV87_03615	COG3321	synthase
KCV87_03625	COG3321	synthase
KCV87_03625	COG0604	alcohol dehydrogenase
KCV87_03635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCV87_03640	COG0546	phosphoglycolate phosphatase activity
KCV87_03655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCV87_03690	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCV87_03775	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KCV87_03780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KCV87_03800	COG0667	Aldo Keto reductase
KCV87_03805	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_03835	COG2197	response regulator
KCV87_03840	COG4585	Histidine kinase
KCV87_03865	COG3507	Belongs to the glycosyl hydrolase 43 family
KCV87_03915	COG2124	cytochrome p450
KCV87_03915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCV87_03920	COG2124	cytochrome p450
KCV87_03920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCV87_03935	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_03970	COG0604	alcohol dehydrogenase
KCV87_03970	COG3321	synthase
KCV87_03980	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCV87_04000	COG3795	YCII-related domain
KCV87_04030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCV87_04035	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCV87_04050	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KCV87_04060	COG0604	alcohol dehydrogenase
KCV87_04060	COG3321	synthase
KCV87_04085	COG0475	glutathione-regulated potassium exporter activity
KCV87_04090	COG1132	(ABC) transporter
KCV87_04100	COG1309	transcriptional regulator
KCV87_04135	COG1024	Enoyl-CoA hydratase
KCV87_04150	COG2409	Drug exporters of the RND superfamily
KCV87_04160	COG2856	Zn peptidase
KCV87_04170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCV87_04175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCV87_04175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCV87_04195	COG1408	metallophosphoesterase
KCV87_04235	COG0659	secondary active sulfate transmembrane transporter activity
KCV87_04245	COG1063	alcohol dehydrogenase
KCV87_04260	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_04295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCV87_04300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCV87_04310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCV87_04325	COG0583	DNA-binding transcription factor activity
KCV87_04330	COG0656	L-ascorbic acid biosynthetic process
KCV87_04385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCV87_04395	COG3903	Transcriptional regulator
KCV87_04395	COG3629	intracellular signal transduction
KCV87_04405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCV87_04415	COG0156	8-amino-7-oxononanoate synthase activity
KCV87_04420	COG0644	oxidoreductase
KCV87_04435	COG3345	alpha-galactosidase
KCV87_04450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCV87_04455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KCV87_04495	COG2814	Major facilitator Superfamily
KCV87_04565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCV87_04570	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_04575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCV87_04580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCV87_04600	COG0367	asparagine synthase
KCV87_04610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCV87_04615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCV87_04620	COG0601	transmembrane transport
KCV87_04660	COG2124	cytochrome p450
KCV87_04675	COG1595	DNA-templated transcription, initiation
KCV87_04685	COG3851	Histidine kinase
KCV87_04695	COG0583	DNA-binding transcription factor activity
KCV87_04705	COG0402	S-adenosylhomocysteine deaminase activity
KCV87_04715	COG1070	Carbohydrate kinase
KCV87_04720	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_04720	COG3347	Dehydrogenase
KCV87_04735	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCV87_04745	COG1129	ABC transporter
KCV87_04755	COG2188	Transcriptional regulator
KCV87_04760	COG0247	lactate metabolic process
KCV87_04765	COG1139	Iron-sulfur cluster binding protein
KCV87_04770	COG1556	Lactate utilization protein
KCV87_04820	COG1132	(ABC) transporter
KCV87_04825	COG1132	(ABC) transporter
KCV87_04830	COG0483	inositol monophosphate 1-phosphatase activity
KCV87_04870	COG3831	ATPase activity
KCV87_04905	COG3903	Transcriptional regulator
KCV87_04905	COG3629	intracellular signal transduction
KCV87_04910	COG2375	cellular response to nickel ion
KCV87_04945	COG0366	Alpha amylase catalytic
KCV87_04955	COG1136	(ABC) transporter
KCV87_04955	COG0577	efflux transmembrane transporter activity
KCV87_04960	COG1136	(ABC) transporter
KCV87_04960	COG0577	efflux transmembrane transporter activity
KCV87_04970	COG2197	response regulator
KCV87_04975	COG0789	Transcriptional regulator
KCV87_04985	COG1309	transcriptional regulator
KCV87_05000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCV87_05005	COG2318	DinB family
KCV87_05025	COG4106	trans-aconitate 2-methyltransferase activity
KCV87_05060	COG1609	Transcriptional regulator
KCV87_05070	COG1501	Belongs to the glycosyl hydrolase 31 family
KCV87_05075	COG0395	ABC-type sugar transport system, permease component
KCV87_05080	COG1175	transmembrane transport
KCV87_05085	COG2182	Extracellular solute-binding protein
KCV87_05115	COG1309	transcriptional regulator
KCV87_05120	COG0494	nUDIX hydrolase
KCV87_05135	COG0673	inositol 2-dehydrogenase activity
KCV87_05165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KCV87_05170	COG3831	ATPase activity
KCV87_05180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCV87_05225	COG3629	intracellular signal transduction
KCV87_05225	COG3903	Transcriptional regulator
KCV87_05330	COG1222	aaa ATPase
KCV87_05370	COG3903	Transcriptional regulator
KCV87_05370	COG3629	intracellular signal transduction
KCV87_05385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCV87_05405	COG0395	ABC-type sugar transport system, permease component
KCV87_05415	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_05420	COG1733	regulation of RNA biosynthetic process
KCV87_05440	COG0784	Response regulator, receiver
KCV87_05450	COG4251	negative regulation of phosphorylation
KCV87_05455	COG3831	ATPase activity
KCV87_05495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_05500	COG1309	transcriptional regulator
KCV87_05505	COG0402	S-adenosylhomocysteine deaminase activity
KCV87_05515	COG0642	Histidine kinase
KCV87_05560	COG2076	Multidrug Resistance protein
KCV87_05575	COG3629	intracellular signal transduction
KCV87_05575	COG3903	Transcriptional regulator
KCV87_05615	COG0135	phosphoribosylanthranilate isomerase activity
KCV87_05650	COG1120	ATPase activity
KCV87_05655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_05675	COG3209	COG3209 Rhs family protein
KCV87_05720	COG1309	transcriptional regulator
KCV87_05740	COG4221	oxidoreductase activity
KCV87_05750	COG3842	ATPase activity
KCV87_05755	COG1176	ABC-type spermidine putrescine transport system, permease component I
KCV87_05760	COG1177	transmembrane transport
KCV87_05775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_05780	COG1473	amidohydrolase
KCV87_05785	COG0028	Belongs to the TPP enzyme family
KCV87_05805	COG2197	response regulator
KCV87_05820	COG0596	Alpha beta hydrolase
KCV87_05830	COG3507	Belongs to the glycosyl hydrolase 43 family
KCV87_05845	COG3833	ABC-type maltose transport systems, permease component
KCV87_05855	COG1653	transport
KCV87_05885	COG3321	synthase
KCV87_05885	COG0604	alcohol dehydrogenase
KCV87_05885	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_05895	COG1131	(ABC) transporter
KCV87_05910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KCV87_05915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCV87_05955	COG2197	response regulator
KCV87_06065	COG2409	Drug exporters of the RND superfamily
KCV87_06085	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_06095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCV87_06100	COG0583	DNA-binding transcription factor activity
KCV87_06110	COG0738	Major facilitator superfamily
KCV87_06125	COG1132	(ABC) transporter
KCV87_06130	COG1309	transcriptional regulator
KCV87_06135	COG0456	acetyltransferase
KCV87_06210	COG0577	efflux transmembrane transporter activity
KCV87_06210	COG1136	(ABC) transporter
KCV87_06220	COG2197	response regulator
KCV87_06225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KCV87_06235	COG0477	Major facilitator Superfamily
KCV87_06310	COG1668	transmembrane transport
KCV87_06315	COG4152	abc transporter atp-binding protein
KCV87_06330	COG0148	phosphopyruvate hydratase activity
KCV87_06345	COG2197	response regulator
KCV87_06350	COG4585	Histidine kinase
KCV87_06365	COG3655	Transcriptional regulator
KCV87_06375	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KCV87_06380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_06390	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_06395	COG1169	isochorismate synthase
KCV87_06400	COG1021	2,3-dihydroxybenzoate-AMP ligase
KCV87_06405	COG3433	isochorismatase activity
KCV87_06405	COG1535	isochorismatase
KCV87_06410	COG1535	isochorismatase
KCV87_06410	COG3433	isochorismatase activity
KCV87_06415	COG2375	cellular response to nickel ion
KCV87_06420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCV87_06425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_06430	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_06435	COG1120	ATPase activity
KCV87_06450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCV87_06500	COG1120	ATPase activity
KCV87_06505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_06520	COG4122	O-methyltransferase activity
KCV87_06555	COG1136	(ABC) transporter
KCV87_06580	COG1509	lysine 2,3-aminomutase activity
KCV87_06600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_06610	COG2267	carboxylic ester hydrolase activity
KCV87_06635	COG0477	Major facilitator Superfamily
KCV87_06655	COG1131	(ABC) transporter
KCV87_06660	COG2197	response regulator
KCV87_06700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCV87_06705	COG0475	glutathione-regulated potassium exporter activity
KCV87_06720	COG1834	amidinotransferase
KCV87_06730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCV87_06730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCV87_06785	COG2084	Dehydrogenase
KCV87_06790	COG1082	Xylose isomerase domain protein TIM barrel
KCV87_06795	COG0149	triose-phosphate isomerase activity
KCV87_06800	COG0698	ribose 5-phosphate isomerase
KCV87_06805	COG2376	Dihydroxyacetone kinase
KCV87_06815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCV87_06855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KCV87_06855	COG2080	2 iron, 2 sulfur cluster binding
KCV87_06865	COG0604	alcohol dehydrogenase
KCV87_06875	COG1253	flavin adenine dinucleotide binding
KCV87_06885	COG2205	protein histidine kinase activity
KCV87_06905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCV87_06915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_06940	COG0346	lactoylglutathione lyase activity
KCV87_06945	COG0640	Transcriptional regulator
KCV87_06960	COG0488	(ABC) transporter
KCV87_06990	COG0702	epimerase
KCV87_06995	COG3384	dioxygenase
KCV87_07000	COG1309	transcriptional regulator
KCV87_07005	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_07060	COG0477	Major facilitator Superfamily
KCV87_07065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCV87_07125	COG1595	DNA-templated transcription, initiation
KCV87_07135	COG1609	Transcriptional regulator
KCV87_07155	COG0395	ABC-type sugar transport system, permease component
KCV87_07245	COG5001	Diguanylate cyclase
KCV87_07255	COG1612	heme a metabolic process
KCV87_07265	COG0477	Major facilitator Superfamily
KCV87_07280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCV87_07325	COG4581	dead DEAH box helicase
KCV87_07335	COG2814	Major facilitator Superfamily
KCV87_07345	COG2124	cytochrome p450
KCV87_07350	COG1653	transport
KCV87_07365	COG0515	serine threonine protein kinase
KCV87_07410	COG3903	Transcriptional regulator
KCV87_07410	COG3629	intracellular signal transduction
KCV87_07425	COG0384	phenazine biosynthesis protein PhzF
KCV87_07460	COG3552	Protein containing von Willebrand factor type A (VWA) domain
KCV87_07465	COG0714	Associated with various cellular activities
KCV87_07500	COG4941	Belongs to the sigma-70 factor family
KCV87_07505	COG3795	YCII-related domain
KCV87_07530	COG1132	(ABC) transporter
KCV87_07535	COG1819	glycosyl
KCV87_07545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCV87_07565	COG2124	cytochrome p450
KCV87_07580	COG0477	Major facilitator Superfamily
KCV87_07640	COG1335	isochorismatase
KCV87_07680	COG1802	Transcriptional regulator
KCV87_07700	COG2205	protein histidine kinase activity
KCV87_07705	COG0745	RESPONSE REGULATOR receiver
KCV87_07730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCV87_07740	COG0747	negative chemotaxis
KCV87_07785	COG2119	membrane
KCV87_07805	COG0604	alcohol dehydrogenase
KCV87_07830	COG0420	3'-5' exonuclease activity
KCV87_07880	COG0277	FAD linked oxidase domain protein
KCV87_07905	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_07935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCV87_07965	COG4585	Histidine kinase
KCV87_07970	COG2197	response regulator
KCV87_07985	COG0395	ABC-type sugar transport system, permease component
KCV87_07990	COG1175	transmembrane transport
KCV87_08000	COG1609	Transcriptional regulator
KCV87_08035	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_08050	COG0326	Molecular chaperone. Has ATPase activity
KCV87_08060	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_08090	COG2814	Major facilitator Superfamily
KCV87_08095	COG1522	sequence-specific DNA binding
KCV87_08115	COG4251	negative regulation of phosphorylation
KCV87_08135	COG1846	Transcriptional regulator
KCV87_08160	COG2204	response regulator
KCV87_08170	COG2205	protein histidine kinase activity
KCV87_08170	COG0745	RESPONSE REGULATOR receiver
KCV87_08170	COG4191	Histidine kinase
KCV87_08180	COG5002	protein histidine kinase activity
KCV87_08210	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KCV87_08215	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KCV87_08225	COG1256	bacterial-type flagellum assembly
KCV87_08225	COG4786	Flagellar basal body rod
KCV87_08250	COG1516	flagellar protein fliS
KCV87_08270	COG1677	Flagellar hook-basal body complex protein FliE
KCV87_08275	COG1766	The M ring may be actively involved in energy transduction
KCV87_08280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCV87_08290	COG1157	protein secretion by the type III secretion system
KCV87_08300	COG0741	lytic transglycosylase activity
KCV87_08315	COG4786	Flagellar basal body rod
KCV87_08325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCV87_08330	COG1360	Flagellar Motor Protein
KCV87_08355	COG1338	Plays a role in the flagellum-specific transport system
KCV87_08360	COG1987	bacterial-type flagellum assembly
KCV87_08370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCV87_08385	COG2198	Histidine kinase
KCV87_08385	COG0643	Histidine kinase
KCV87_08385	COG0784	Response regulator, receiver
KCV87_08390	COG0835	chemotaxis
KCV87_08405	COG2201	protein-glutamate methylesterase activity
KCV87_08415	COG0745	RESPONSE REGULATOR receiver
KCV87_08425	COG0745	RESPONSE REGULATOR receiver
KCV87_08435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCV87_08450	COG2205	protein histidine kinase activity
KCV87_08455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_08460	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KCV87_08500	COG0277	FAD linked oxidase domain protein
KCV87_08510	COG0673	inositol 2-dehydrogenase activity
KCV87_08515	COG1940	carbohydrate kinase activity
KCV87_08525	COG2226	methyltransferase
KCV87_08545	COG3845	ABC transporter
KCV87_08565	COG1716	ATPase activity
KCV87_08565	COG5001	Diguanylate cyclase
KCV87_08570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KCV87_08600	COG0187	DNA topoisomerase II activity
KCV87_08615	COG1703	isobutyryl-CoA mutase activity
KCV87_08615	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KCV87_08615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KCV87_08625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCV87_08635	COG0714	Associated with various cellular activities
KCV87_08640	COG1846	Transcriptional regulator
KCV87_08660	COG2357	RelA SpoT domain protein
KCV87_08685	COG3706	GGDEF domain
KCV87_08715	COG4552	Acetyltransferase involved in intracellular survival and related
KCV87_08740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCV87_08750	COG2378	regulation of single-species biofilm formation
KCV87_08765	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KCV87_08785	COG4221	oxidoreductase activity
KCV87_08790	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KCV87_08795	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KCV87_08835	COG4585	Histidine kinase
KCV87_08840	COG2197	response regulator
KCV87_08845	COG1222	aaa ATPase
KCV87_08875	COG2197	response regulator
KCV87_08880	COG0300	oxidoreductase activity
KCV87_08885	COG1994	Peptidase M50
KCV87_08885	COG0517	IMP dehydrogenase activity
KCV87_08910	COG0140	phosphoribosyl-ATP diphosphatase activity
KCV87_08925	COG0446	pyridine nucleotide-disulphide oxidoreductase
KCV87_08925	COG1902	pentaerythritol trinitrate reductase activity
KCV87_08940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCV87_08945	COG0646	methionine synthase
KCV87_08945	COG1410	methionine synthase
KCV87_08955	COG5002	protein histidine kinase activity
KCV87_08960	COG0745	RESPONSE REGULATOR receiver
KCV87_08965	COG0745	RESPONSE REGULATOR receiver
KCV87_08995	COG0215	cysteine-tRNA ligase activity
KCV87_09010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCV87_09045	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KCV87_09050	COG5297	Belongs to the glycosyl hydrolase family 6
KCV87_09080	COG4221	oxidoreductase activity
KCV87_09095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KCV87_09100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KCV87_09110	COG0277	FAD linked oxidase domain protein
KCV87_09110	COG0247	lactate metabolic process
KCV87_09125	COG0789	Transcriptional regulator
KCV87_09130	COG1324	tolerance protein
KCV87_09145	COG0395	ABC-type sugar transport system, permease component
KCV87_09150	COG4209	transmembrane transport
KCV87_09165	COG1472	Belongs to the glycosyl hydrolase 3 family
KCV87_09170	COG5297	Belongs to the glycosyl hydrolase family 6
KCV87_09170	COG4733	cellulase activity
KCV87_09180	COG3012	SEC-C Motif Domain Protein
KCV87_09200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCV87_09255	COG5002	protein histidine kinase activity
KCV87_09270	COG2304	oxidoreductase activity
KCV87_09280	COG0714	Associated with various cellular activities
KCV87_09285	COG0500	methyltransferase
KCV87_09290	COG0746	molybdenum cofactor guanylyltransferase activity
KCV87_09300	COG0791	NLP P60 protein
KCV87_09300	COG3883	PFAM NLP P60 protein
KCV87_09305	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_09315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KCV87_09340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCV87_09380	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KCV87_09390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCV87_09395	COG3572	ergothioneine biosynthetic process
KCV87_09425	COG2124	cytochrome p450
KCV87_09435	COG0477	Major facilitator Superfamily
KCV87_09440	COG1309	transcriptional regulator
KCV87_09455	COG0217	transcriptional regulatory protein
KCV87_09460	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KCV87_09465	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KCV87_09500	COG1953	Uracil, thiamine, allantoin
KCV87_09510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCV87_09530	COG1051	belongs to the nudix hydrolase family
KCV87_09535	COG0438	transferase activity, transferring glycosyl groups
KCV87_09540	COG1560	Kdo2-lipid A biosynthetic process
KCV87_09545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCV87_09560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCV87_09605	COG2186	Transcriptional regulator
KCV87_09620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCV87_09630	COG0531	amino acid
KCV87_09635	COG2340	Cysteine-rich secretory protein family
KCV87_09645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCV87_09655	COG0492	ferredoxin-NADP+ reductase activity
KCV87_09685	COG3835	regulator
KCV87_09695	COG0590	tRNA wobble adenosine to inosine editing
KCV87_09715	COG3842	ATPase activity
KCV87_09740	COG1174	glycine betaine transport
KCV87_09750	COG1174	glycine betaine transport
KCV87_09755	COG1732	Glycine betaine
KCV87_09760	COG5297	Belongs to the glycosyl hydrolase family 6
KCV87_09765	COG3250	beta-galactosidase activity
KCV87_09800	COG1140	nitrate reductase beta subunit
KCV87_09805	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KCV87_09810	COG2181	nitrate reductase activity
KCV87_09855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCV87_09875	COG3483	tryptophan 2,3-dioxygenase activity
KCV87_09885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCV87_09890	COG1834	amidinotransferase
KCV87_09925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KCV87_09930	COG2188	Transcriptional regulator
KCV87_10070	COG1595	DNA-templated transcription, initiation
KCV87_10100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCV87_10115	COG2197	response regulator
KCV87_10140	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KCV87_10155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCV87_10165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCV87_10180	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KCV87_10185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCV87_10195	COG1295	ribonuclease BN
KCV87_10210	COG1011	Hydrolase
KCV87_10240	COG0542	response to heat
KCV87_10250	COG1609	Transcriptional regulator
KCV87_10260	COG4209	transmembrane transport
KCV87_10265	COG0395	ABC-type sugar transport system, permease component
KCV87_10295	COG2264	protein methyltransferase activity
KCV87_10315	COG2197	response regulator
KCV87_10335	COG1846	Transcriptional regulator
KCV87_10355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KCV87_10360	COG2124	cytochrome p450
KCV87_10400	COG0477	Major facilitator Superfamily
KCV87_10465	COG1131	(ABC) transporter
KCV87_10475	COG4585	Histidine kinase
KCV87_10480	COG2197	response regulator
KCV87_10500	COG0745	RESPONSE REGULATOR receiver
KCV87_10510	COG0702	epimerase
KCV87_10520	COG0395	ABC-type sugar transport system, permease component
KCV87_10545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCV87_10555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KCV87_10555	COG2755	lipolytic protein G-D-S-L family
KCV87_10565	COG0515	serine threonine protein kinase
KCV87_10565	COG2815	serine threonine protein kinase
KCV87_10570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCV87_10575	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KCV87_10650	COG2261	transglycosylase associated protein
KCV87_10655	COG2326	polyphosphate kinase activity
KCV87_10660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCV87_10675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCV87_10700	COG0438	transferase activity, transferring glycosyl groups
KCV87_10705	COG3831	ATPase activity
KCV87_10710	COG3831	ATPase activity
KCV87_10715	COG3831	ATPase activity
KCV87_10720	COG0714	Associated with various cellular activities
KCV87_10725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KCV87_10730	COG3552	Protein containing von Willebrand factor type A (VWA) domain
KCV87_10735	COG4715	Zinc finger, swim domain protein
KCV87_10740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCV87_10760	COG4585	Histidine kinase
KCV87_10770	COG2356	endonuclease I
KCV87_10795	COG1609	Transcriptional regulator
KCV87_10810	COG3401	FG-GAP repeat protein
KCV87_10825	COG4214	carbohydrate transport
KCV87_10835	COG4213	ABC transporter substrate-binding protein
KCV87_10840	COG2160	L-arabinose isomerase activity
KCV87_10855	COG1609	Transcriptional regulator
KCV87_10865	COG3940	Belongs to the glycosyl hydrolase 43 family
KCV87_10880	COG1879	ABC-type sugar transport system periplasmic component
KCV87_10890	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCV87_10895	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCV87_10920	COG4948	Mandelate Racemase Muconate Lactonizing
KCV87_10930	COG0395	ABC-type sugar transport system, permease component
KCV87_10940	COG3866	Pectate lyase
KCV87_10955	COG1785	Belongs to the alkaline phosphatase family
KCV87_10960	COG0492	ferredoxin-NADP+ reductase activity
KCV87_10990	COG4941	Belongs to the sigma-70 factor family
KCV87_11015	COG3458	cephalosporin-C deacetylase activity
KCV87_11025	COG1472	Belongs to the glycosyl hydrolase 3 family
KCV87_11030	COG1609	Transcriptional regulator
KCV87_11035	COG1609	Transcriptional regulator
KCV87_11055	COG0791	NLP P60 protein
KCV87_11095	COG0640	Transcriptional regulator
KCV87_11150	COG2207	Transcriptional regulator
KCV87_11150	COG3708	Transcriptional regulator
KCV87_11180	COG1070	Carbohydrate kinase
KCV87_11185	COG2115	Belongs to the xylose isomerase family
KCV87_11195	COG1940	carbohydrate kinase activity
KCV87_11200	COG4249	Peptidase C14 caspase catalytic subunit p20
KCV87_11200	COG2319	Wd-40 repeat
KCV87_11205	COG5416	Lipopolysaccharide assembly protein A domain
KCV87_11225	COG2723	6-phospho-beta-galactosidase activity
KCV87_11230	COG0395	ABC-type sugar transport system, permease component
KCV87_11250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCV87_11285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCV87_11295	COG0765	amino acid transport
KCV87_11300	COG1126	abc transporter atp-binding protein
KCV87_11315	COG1295	ribonuclease BN
KCV87_11340	COG1024	Enoyl-CoA hydratase
KCV87_11345	COG0596	Alpha beta hydrolase
KCV87_11345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCV87_11345	COG2226	methyltransferase
KCV87_11350	COG0667	Aldo Keto reductase
KCV87_11440	COG2244	polysaccharide biosynthetic process
KCV87_11480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCV87_11495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCV87_11510	COG0673	inositol 2-dehydrogenase activity
KCV87_11535	COG2372	response to copper ion
KCV87_11545	COG0745	RESPONSE REGULATOR receiver
KCV87_11550	COG2205	protein histidine kinase activity
KCV87_11555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCV87_11570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KCV87_11600	COG0439	Biotin carboxylase
KCV87_11605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCV87_11655	COG0124	histidyl-tRNA synthetase
KCV87_11665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCV87_11670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCV87_11675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCV87_11680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCV87_11705	COG0632	four-way junction helicase activity
KCV87_11710	COG2255	four-way junction helicase activity
KCV87_11715	COG2318	DinB family
KCV87_11720	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KCV87_11750	COG0444	Belongs to the ABC transporter superfamily
KCV87_11755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCV87_11760	COG0601	transmembrane transport
KCV87_11845	COG3903	Transcriptional regulator
KCV87_11845	COG3629	intracellular signal transduction
KCV87_11850	COG3345	alpha-galactosidase
KCV87_11865	COG0328	RNA-DNA hybrid ribonuclease activity
KCV87_12020	COG2197	response regulator
KCV87_12030	COG1131	(ABC) transporter
KCV87_12065	COG1215	transferase activity, transferring glycosyl groups
KCV87_12075	COG0438	transferase activity, transferring glycosyl groups
KCV87_12085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCV87_12090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCV87_12100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCV87_12125	COG2826	transposase and inactivated derivatives, IS30 family
KCV87_12135	COG2963	transposase activity
KCV87_12155	COG1132	(ABC) transporter
KCV87_12220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCV87_12235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCV87_12315	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCV87_12345	COG4585	Histidine kinase
KCV87_12350	COG2197	response regulator
KCV87_12355	COG1160	GTP binding
KCV87_12375	COG0475	glutathione-regulated potassium exporter activity
KCV87_12425	COG1309	transcriptional regulator
KCV87_12450	COG1960	acyl-CoA dehydrogenase activity
KCV87_12465	COG0653	protein targeting
KCV87_12475	COG0671	phosphoesterase, PA-phosphatase related
KCV87_12485	COG1316	TRANSCRIPTIONal
KCV87_12510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCV87_12515	COG2706	6-phosphogluconolactonase activity
KCV87_12525	COG0488	(ABC) transporter
KCV87_12545	COG1793	dna ligase
KCV87_12585	COG1793	dna ligase
KCV87_12585	COG3285	dna ligase
KCV87_12590	COG1960	acyl-CoA dehydrogenase activity
KCV87_12595	COG1960	acyl-CoA dehydrogenase activity
KCV87_12615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCV87_12645	COG3220	belongs to the UPF0276 family
KCV87_12665	COG1404	Belongs to the peptidase S8 family
KCV87_12670	COG3253	May function as heme-dependent peroxidase
KCV87_12675	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KCV87_12680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KCV87_12700	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KCV87_12720	COG0183	Belongs to the thiolase family
KCV87_12725	COG1024	Enoyl-CoA hydratase
KCV87_12725	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCV87_12820	COG2205	protein histidine kinase activity
KCV87_12825	COG0745	RESPONSE REGULATOR receiver
KCV87_12835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCV87_12840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCV87_12845	COG0531	amino acid
KCV87_12850	COG0569	domain protein
KCV87_12880	COG0756	dUTP diphosphatase activity
KCV87_12930	COG4214	carbohydrate transport
KCV87_12945	COG1061	Type III restriction enzyme res subunit
KCV87_12960	COG2313	pseudouridylate synthase activity
KCV87_12980	COG2890	protein-(glutamine-N5) methyltransferase activity
KCV87_12985	COG1490	D-aminoacyl-tRNA deacylase activity
KCV87_12995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KCV87_12995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KCV87_13015	COG4948	Mandelate Racemase Muconate Lactonizing
KCV87_13020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCV87_13030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCV87_13075	COG1690	Belongs to the RtcB family
KCV87_13095	COG2188	Transcriptional regulator
KCV87_13100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCV87_13110	COG0123	including yeast histone deacetylase and acetoin utilization protein
KCV87_13135	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCV87_13140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KCV87_13145	COG0823	Involved in the tonB-independent uptake of proteins
KCV87_13145	COG4946	Tricorn protease homolog
KCV87_13145	COG1506	peptidase
KCV87_13155	COG2936	dipeptidyl-peptidase activity
KCV87_13160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCV87_13165	COG1486	melibiose metabolic process
KCV87_13170	COG1515	deoxyribonuclease V activity
KCV87_13200	COG0765	amino acid transport
KCV87_13205	COG0765	amino acid transport
KCV87_13215	COG1126	abc transporter atp-binding protein
KCV87_13220	COG0745	RESPONSE REGULATOR receiver
KCV87_13225	COG0642	Histidine kinase
KCV87_13230	COG2358	TRAP transporter, solute receptor (TAXI family
KCV87_13235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KCV87_13245	COG1196	nuclear chromosome segregation
KCV87_13255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCV87_13260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KCV87_13275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCV87_13285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCV87_13295	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCV87_13300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCV87_13340	COG0800	Aldolase
KCV87_13350	COG2137	regulation of response to DNA damage stimulus
KCV87_13355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCV87_13365	COG2814	Major facilitator Superfamily
KCV87_13370	COG0443	Heat shock 70 kDa protein
KCV87_13380	COG1201	RNA secondary structure unwinding
KCV87_13410	COG0442	prolyl-tRNA aminoacylation
KCV87_13435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCV87_13445	COG0142	geranyltranstransferase activity
KCV87_13470	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KCV87_13500	COG1940	carbohydrate kinase activity
KCV87_13510	COG0003	Pfam Anion-transporting ATPase
KCV87_13535	COG0438	transferase activity, transferring glycosyl groups
KCV87_13565	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCV87_13575	COG2010	Cytochrome c
KCV87_13580	COG1845	cytochrome c oxidase, subunit III
KCV87_13595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCV87_13600	COG0204	Acyl-transferase
KCV87_13600	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_13610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCV87_13645	COG0667	Aldo Keto reductase
KCV87_13660	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KCV87_13665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCV87_13690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCV87_13695	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCV87_13710	COG0702	epimerase
KCV87_13725	COG0321	lipoyl(octanoyl) transferase activity
KCV87_13745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KCV87_13780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KCV87_13790	COG1653	transport
KCV87_13795	COG3201	nicotinamide mononucleotide transporter
KCV87_13820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCV87_13825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCV87_13840	COG0515	serine threonine protein kinase
KCV87_13850	COG1132	(ABC) transporter
KCV87_13855	COG1132	(ABC) transporter
KCV87_13890	COG2084	Dehydrogenase
KCV87_13905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCV87_13910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCV87_13925	COG5001	Diguanylate cyclase
KCV87_13940	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KCV87_13960	COG1316	TRANSCRIPTIONal
KCV87_13970	COG4106	trans-aconitate 2-methyltransferase activity
KCV87_14020	COG1674	ftsk spoiiie
KCV87_14065	COG0358	DNA primase activity
KCV87_14070	COG1595	DNA-templated transcription, initiation
KCV87_14075	COG3340	Belongs to the peptidase S51 family
KCV87_14085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KCV87_14110	COG0423	glycine-tRNA ligase activity
KCV87_14145	COG0701	Predicted permease
KCV87_14160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCV87_14165	COG1381	Involved in DNA repair and RecF pathway recombination
KCV87_14170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCV87_14190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCV87_14205	COG0537	adenosine 5'-monophosphoramidase activity
KCV87_14210	COG0596	Alpha beta hydrolase
KCV87_14230	COG0484	heat shock protein binding
KCV87_14245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCV87_14275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KCV87_14280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCV87_14300	COG2732	(Barnase) inhibitor
KCV87_14315	COG0604	alcohol dehydrogenase
KCV87_14325	COG0531	amino acid
KCV87_14345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCV87_14360	COG0481	GTPase activity
KCV87_14365	COG1305	Transglutaminase-like
KCV87_14375	COG2308	Evidence 4 Homologs of previously reported genes of
KCV87_14405	COG0268	Binds directly to 16S ribosomal RNA
KCV87_14425	COG0658	competence protein
KCV87_14425	COG2333	competence protein COMEC
KCV87_14430	COG1596	polysaccharide export
KCV87_14430	COG1555	photosystem II stabilization
KCV87_14435	COG1307	EDD domain protein, DegV family
KCV87_14440	COG2755	lipolytic protein G-D-S-L family
KCV87_14450	COG0799	negative regulation of ribosome biogenesis
KCV87_14455	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCV87_14470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCV87_14485	COG0477	Major facilitator Superfamily
KCV87_14495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCV87_14500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KCV87_14505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KCV87_14510	COG1530	ribonuclease E activity
KCV87_14510	COG1530	ribonuclease E activity
KCV87_14560	COG0842	Transport permease protein
KCV87_14570	COG1131	(ABC) transporter
KCV87_14575	COG0105	UTP biosynthetic process
KCV87_14720	COG0285	dihydrofolate synthase activity
KCV87_14725	COG0525	valine-tRNA ligase activity
KCV87_14770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KCV87_14785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCV87_14790	COG0740	serine-type endopeptidase activity
KCV87_14795	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCV87_14800	COG0583	DNA-binding transcription factor activity
KCV87_14820	COG4552	Acetyltransferase involved in intracellular survival and related
KCV87_14850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCV87_14860	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KCV87_14880	COG1505	serine-type exopeptidase activity
KCV87_14885	COG0668	transmembrane transport
KCV87_14895	COG0366	Alpha amylase catalytic
KCV87_14920	COG2902	Dehydrogenase
KCV87_14955	COG3336	cytochrome c oxidase
KCV87_14965	COG2223	nitrite transmembrane transporter activity
KCV87_14970	COG1609	Transcriptional regulator
KCV87_14985	COG0740	serine-type endopeptidase activity
KCV87_14990	COG0740	serine-type endopeptidase activity
KCV87_15035	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_15060	COG0706	membrane insertase activity
KCV87_15070	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_15075	COG0506	proline dehydrogenase activity
KCV87_15080	COG4106	trans-aconitate 2-methyltransferase activity
KCV87_15120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCV87_15120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCV87_15140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KCV87_15145	COG1846	Transcriptional regulator
KCV87_15175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCV87_15175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCV87_15205	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KCV87_15215	COG0488	(ABC) transporter
KCV87_15220	COG1376	ErfK ybiS ycfS ynhG family protein
KCV87_15260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCV87_15265	COG4279	zinc finger
KCV87_15275	COG3345	alpha-galactosidase
KCV87_15285	COG1278	Cold shock
KCV87_15295	COG4213	ABC transporter substrate-binding protein
KCV87_15305	COG0751	glycine-tRNA ligase activity
KCV87_15305	COG0752	glycyl-tRNA synthetase alpha subunit
KCV87_15310	COG1316	TRANSCRIPTIONal
KCV87_15315	COG2949	membrane
KCV87_15365	COG0586	Pfam SNARE associated Golgi protein
KCV87_15370	COG2072	flavoprotein involved in K transport
KCV87_15375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_15395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCV87_15400	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KCV87_15420	COG1234	tRNA 3'-trailer cleavage
KCV87_15425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KCV87_15435	COG3386	PFAM SMP-30 Gluconolaconase
KCV87_15440	COG1234	tRNA 3'-trailer cleavage
KCV87_15475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KCV87_15480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCV87_15485	COG1335	isochorismatase
KCV87_15495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KCV87_15550	COG0560	Phosphoserine phosphatase
KCV87_15550	COG3830	Belongs to the UPF0237 family
KCV87_15555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCV87_15565	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KCV87_15570	COG0235	Class ii aldolase
KCV87_15575	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KCV87_15580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KCV87_15615	COG3903	Transcriptional regulator
KCV87_15615	COG3629	intracellular signal transduction
KCV87_15620	COG1609	Transcriptional regulator
KCV87_15625	COG3254	rhamnose metabolic process
KCV87_15635	COG0395	ABC-type sugar transport system, permease component
KCV87_15640	COG1175	transmembrane transport
KCV87_15675	COG3903	Transcriptional regulator
KCV87_15675	COG3629	intracellular signal transduction
KCV87_15680	COG0210	DNA helicase
KCV87_15685	COG1205	dead DEAH box helicase
KCV87_15685	COG1111	helicase
KCV87_15695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCV87_15795	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KCV87_15805	COG2814	Major facilitator Superfamily
KCV87_15810	COG0454	-acetyltransferase
KCV87_15810	COG0456	acetyltransferase
KCV87_15820	COG1643	Atp-dependent helicase
KCV87_15835	COG4585	Histidine kinase
KCV87_15840	COG2197	response regulator
KCV87_15845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCV87_15850	COG2177	Part of the ABC transporter FtsEX involved in
KCV87_15855	COG2884	Cell division ATP-binding protein ftsE
KCV87_15860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCV87_15890	COG1615	UPF0182 protein
KCV87_15925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KCV87_15995	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KCV87_16010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCV87_16010	COG0519	Catalyzes the synthesis of GMP from XMP
KCV87_16020	COG1522	sequence-specific DNA binding
KCV87_16050	COG0174	glutamine synthetase
KCV87_16055	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KCV87_16055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCV87_16075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KCV87_16095	COG3842	ATPase activity
KCV87_16125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCV87_16145	COG0791	NLP P60 protein
KCV87_16185	COG0431	NADPH-dependent FMN reductase
KCV87_16230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KCV87_16260	COG1940	carbohydrate kinase activity
KCV87_16260	COG1846	Transcriptional regulator
KCV87_16270	COG0612	Peptidase, M16
KCV87_16310	COG0583	DNA-binding transcription factor activity
KCV87_16315	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_16330	COG0210	DNA helicase
KCV87_16365	COG2205	protein histidine kinase activity
KCV87_16370	COG0745	RESPONSE REGULATOR receiver
KCV87_16395	COG2146	nitrite reductase [NAD(P)H] activity
KCV87_16395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCV87_16400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCV87_16400	COG2146	nitrite reductase [NAD(P)H] activity
KCV87_16405	COG2223	nitrite transmembrane transporter activity
KCV87_16410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCV87_16415	COG0243	molybdopterin cofactor binding
KCV87_16435	COG2267	carboxylic ester hydrolase activity
KCV87_16470	COG0513	Belongs to the DEAD box helicase family
KCV87_16510	COG0598	Magnesium transport protein CorA
KCV87_16570	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
KCV87_16575	COG2239	Acts as a magnesium transporter
KCV87_16595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCV87_16600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCV87_16615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCV87_16620	COG0297	glycogen (starch) synthase activity
KCV87_16625	COG2814	Major facilitator Superfamily
KCV87_16630	COG0583	DNA-binding transcription factor activity
KCV87_16635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCV87_16645	COG3327	negative regulation of DNA-templated transcription, initiation
KCV87_16650	COG1024	Enoyl-CoA hydratase
KCV87_16675	COG0519	Catalyzes the synthesis of GMP from XMP
KCV87_16695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCV87_16705	COG1611	Belongs to the LOG family
KCV87_16710	COG1611	Belongs to the LOG family
KCV87_16715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCV87_16750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCV87_16755	COG4608	Belongs to the ABC transporter superfamily
KCV87_16775	COG4166	transmembrane transport
KCV87_16780	COG0747	negative chemotaxis
KCV87_16785	COG1217	gtp-binding protein TYPA
KCV87_16800	COG0180	Tryptophanyl-tRNA synthetase
KCV87_16805	COG0494	nUDIX hydrolase
KCV87_16825	COG1131	(ABC) transporter
KCV87_16840	COG3842	ATPase activity
KCV87_16845	COG4149	molybdate abc transporter
KCV87_16855	COG2154	pterin-4-alpha-carbinolamine dehydratase
KCV87_16865	COG1051	belongs to the nudix hydrolase family
KCV87_16895	COG0012	GTP binding
KCV87_16910	COG0419	ATPase involved in DNA repair
KCV87_16940	COG1570	exodeoxyribonuclease VII activity
KCV87_16950	COG1722	exodeoxyribonuclease VII activity
KCV87_16970	COG0492	ferredoxin-NADP+ reductase activity
KCV87_16975	COG0114	fumarate hydratase activity
KCV87_16980	COG1793	dna ligase
KCV87_16990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KCV87_17005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCV87_17015	COG1331	Highly conserved protein containing a thioredoxin domain
KCV87_17030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCV87_17040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCV87_17050	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KCV87_17080	COG0183	Belongs to the thiolase family
KCV87_17150	COG0714	Associated with various cellular activities
KCV87_17175	COG4608	Belongs to the ABC transporter superfamily
KCV87_17185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCV87_17190	COG0601	transmembrane transport
KCV87_17195	COG4166	transmembrane transport
KCV87_17220	COG0148	phosphopyruvate hydratase activity
KCV87_17235	COG4946	Tricorn protease homolog
KCV87_17235	COG0793	Belongs to the peptidase S41A family
KCV87_17240	COG3956	TIGRFAM MazG family protein
KCV87_17260	COG2133	pyrroloquinoline quinone binding
KCV87_17295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCV87_17315	COG0193	aminoacyl-tRNA hydrolase activity
KCV87_17320	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_17340	COG3599	regulation of cell shape
KCV87_17345	COG0488	(ABC) transporter
KCV87_17350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCV87_17360	COG2011	ABC-type metal ion transport system permease component
KCV87_17365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCV87_17370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCV87_17375	COG3583	domain protein
KCV87_17380	COG0084	hydrolase, TatD family'
KCV87_17385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCV87_17420	COG0515	serine threonine protein kinase
KCV87_17450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCV87_17460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCV87_17465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCV87_17480	COG1970	mechanosensitive ion channel activity
KCV87_17490	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCV87_17490	COG0315	cyclic pyranopterin monophosphate synthase activity
KCV87_17495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCV87_17505	COG1349	DNA-binding transcription factor activity
KCV87_17515	COG1653	transport
KCV87_17520	COG1175	transmembrane transport
KCV87_17525	COG0395	ABC-type sugar transport system, permease component
KCV87_17530	COG2205	protein histidine kinase activity
KCV87_17555	COG0588	phosphoglycerate mutase activity
KCV87_17560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KCV87_17570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCV87_17575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCV87_17580	COG0778	Nitroreductase
KCV87_17590	COG2197	response regulator
KCV87_17680	COG3209	COG3209 Rhs family protein
KCV87_17730	COG2319	Wd-40 repeat
KCV87_17730	COG4249	Peptidase C14 caspase catalytic subunit p20
KCV87_17740	COG2197	response regulator
KCV87_17775	COG1733	regulation of RNA biosynthetic process
KCV87_17780	COG0702	epimerase
KCV87_17785	COG0583	DNA-binding transcription factor activity
KCV87_17790	COG0384	phenazine biosynthesis protein PhzF
KCV87_17795	COG0583	DNA-binding transcription factor activity
KCV87_17800	COG2267	carboxylic ester hydrolase activity
KCV87_17825	COG1674	ftsk spoiiie
KCV87_17840	COG2130	NADP-dependent
KCV87_17845	COG0402	S-adenosylhomocysteine deaminase activity
KCV87_17870	COG4152	abc transporter atp-binding protein
KCV87_17875	COG1668	transmembrane transport
KCV87_17885	COG2197	response regulator
KCV87_17890	COG0415	Belongs to the DNA photolyase family
KCV87_17910	COG1960	acyl-CoA dehydrogenase activity
KCV87_17915	COG1228	amidohydrolase
KCV87_17920	COG2017	converts alpha-aldose to the beta-anomer
KCV87_17925	COG0531	amino acid
KCV87_17930	COG1309	transcriptional regulator
KCV87_17940	COG1132	(ABC) transporter
KCV87_17945	COG1132	(ABC) transporter
KCV87_17970	COG2197	response regulator
KCV87_17995	COG0831	urea catabolic process
KCV87_18000	COG0832	Belongs to the urease beta subunit family
KCV87_18005	COG0804	urea catabolic process
KCV87_18015	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KCV87_18025	COG0829	nickel cation binding
KCV87_18030	COG0259	pyridoxamine-phosphate oxidase activity
KCV87_18035	COG5492	domain, Protein
KCV87_18055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCV87_18070	COG0488	(ABC) transporter
KCV87_18085	COG2814	Major facilitator Superfamily
KCV87_18095	COG2252	PERMEase
KCV87_18120	COG2814	Major facilitator Superfamily
KCV87_18130	COG1278	Cold shock
KCV87_18155	COG3304	Inner membrane component domain
KCV87_18175	COG1846	Transcriptional regulator
KCV87_18180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KCV87_18190	COG1388	LysM domain
KCV87_18200	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCV87_18200	COG0315	cyclic pyranopterin monophosphate synthase activity
KCV87_18240	COG2018	Roadblock/LC7 domain
KCV87_18275	COG4948	Mandelate Racemase Muconate Lactonizing
KCV87_18290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KCV87_18295	COG0395	ABC-type sugar transport system, permease component
KCV87_18300	COG1175	transmembrane transport
KCV87_18310	COG3142	Participates in the control of copper homeostasis
KCV87_18325	COG0459	protein refolding
KCV87_18335	COG1278	Cold shock
KCV87_18355	COG0688	phosphatidylethanolamine metabolic process
KCV87_18375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCV87_18385	COG1802	Transcriptional regulator
KCV87_18410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KCV87_18415	COG0351	phosphomethylpyrimidine kinase
KCV87_18445	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_18470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KCV87_18480	COG2022	thiamine diphosphate biosynthetic process
KCV87_18490	COG2022	thiamine diphosphate biosynthetic process
KCV87_18490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCV87_18495	COG0352	thiamine-phosphate diphosphorylase activity
KCV87_18500	COG3384	dioxygenase
KCV87_18505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCV87_18510	COG2188	Transcriptional regulator
KCV87_18515	COG2182	Extracellular solute-binding protein
KCV87_18520	COG1175	transmembrane transport
KCV87_18525	COG0395	ABC-type sugar transport system, permease component
KCV87_18530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCV87_18535	COG2186	Transcriptional regulator
KCV87_18555	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_18560	COG4948	Mandelate Racemase Muconate Lactonizing
KCV87_18565	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCV87_18570	COG1404	Belongs to the peptidase S8 family
KCV87_18580	COG0583	DNA-binding transcription factor activity
KCV87_18585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_18605	COG3629	intracellular signal transduction
KCV87_18605	COG3903	Transcriptional regulator
KCV87_18635	COG0745	RESPONSE REGULATOR receiver
KCV87_18640	COG2205	protein histidine kinase activity
KCV87_18675	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KCV87_18685	COG4221	oxidoreductase activity
KCV87_18705	COG1329	Transcriptional regulator
KCV87_18710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KCV87_18715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KCV87_18725	COG0215	cysteine-tRNA ligase activity
KCV87_18755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCV87_18760	COG1121	(ABC) transporter
KCV87_18770	COG3842	ATPase activity
KCV87_18775	COG3833	ABC-type maltose transport systems, permease component
KCV87_18785	COG1653	transport
KCV87_18795	COG1609	Transcriptional regulator
KCV87_18810	COG1194	a g-specific adenine glycosylase
KCV87_18835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KCV87_18845	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KCV87_18860	COG1120	ATPase activity
KCV87_18865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_18870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_18880	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KCV87_18890	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KCV87_18895	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KCV87_18900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KCV87_18925	COG0649	NAD binding
KCV87_18945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCV87_18950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCV87_18955	COG0302	gtp cyclohydrolase
KCV87_18960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCV87_18970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KCV87_18975	COG0037	tRNA processing
KCV87_18985	COG2027	D-alanyl-D-alanine carboxypeptidase
KCV87_18990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KCV87_19035	COG1120	ATPase activity
KCV87_19040	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KCV87_19060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCV87_19065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCV87_19075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCV87_19075	COG1754	DNA topoisomerase type I activity
KCV87_19105	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KCV87_19110	COG1205	dead DEAH box helicase
KCV87_19110	COG1111	helicase
KCV87_19160	COG1472	Belongs to the glycosyl hydrolase 3 family
KCV87_19165	COG3876	Protein conserved in bacteria
KCV87_19175	COG1737	Transcriptional regulator
KCV87_19180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KCV87_19185	COG1522	sequence-specific DNA binding
KCV87_19195	COG3844	kynureninase activity
KCV87_19210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCV87_19215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KCV87_19225	COG0596	Alpha beta hydrolase
KCV87_19240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCV87_19260	COG2814	Major facilitator Superfamily
KCV87_19265	COG0592	DNA-directed DNA polymerase activity
KCV87_19355	COG1408	metallophosphoesterase
KCV87_19400	COG0431	NADPH-dependent FMN reductase
KCV87_19410	COG1764	response to oxidative stress
KCV87_19425	COG1278	Cold shock
KCV87_19430	COG1070	Carbohydrate kinase
KCV87_19470	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KCV87_19475	COG4608	Belongs to the ABC transporter superfamily
KCV87_19480	COG0444	Belongs to the ABC transporter superfamily
KCV87_19485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCV87_19490	COG0601	transmembrane transport
KCV87_19495	COG0747	negative chemotaxis
KCV87_19500	COG3629	intracellular signal transduction
KCV87_19500	COG3903	Transcriptional regulator
KCV87_19525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCV87_19530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCV87_19595	COG1473	amidohydrolase
KCV87_19600	COG0287	Prephenate dehydrogenase
KCV87_19615	COG0183	Belongs to the thiolase family
KCV87_19660	COG5295	Hep Hag repeat protein
KCV87_19660	COG4932	domain protein
KCV87_19665	COG1686	Belongs to the peptidase S11 family
KCV87_19685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCV87_19710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCV87_19730	COG0737	Belongs to the 5'-nucleotidase family
KCV87_19730	COG4085	toxin activity
KCV87_19730	COG1525	nuclease
KCV87_19740	COG2234	aminopeptidase activity
KCV87_19785	COG1216	Glycosyl transferase, family 2
KCV87_19815	COG1216	Glycosyl transferase, family 2
KCV87_19835	COG0463	Glycosyl transferase, family 2
KCV87_19845	COG0561	phosphatase activity
KCV87_19855	COG0579	oxidoreductase
KCV87_19870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCV87_19880	COG3766	membrane
KCV87_19885	COG0754	glutathionylspermidine amidase activity
KCV87_19920	COG1501	Belongs to the glycosyl hydrolase 31 family
KCV87_19980	COG0454	-acetyltransferase
KCV87_19995	COG4988	ABC transporter
KCV87_20005	COG1294	oxidase, subunit
KCV87_20010	COG1271	oxidase subunit
KCV87_20060	COG1528	Iron-storage protein
KCV87_20075	COG0653	protein targeting
KCV87_20090	COG0584	glycerophosphoryl diester phosphodiesterase
KCV87_20115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCV87_20125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCV87_20135	COG3279	Response regulator of the LytR AlgR family
KCV87_20150	COG3275	phosphorelay sensor kinase activity
KCV87_20185	COG2226	methyltransferase
KCV87_20200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCV87_20230	COG0405	Gamma-glutamyltransferase
KCV87_20280	COG3281	Trehalose synthase
KCV87_20290	COG0300	oxidoreductase activity
KCV87_20295	COG2211	Major facilitator Superfamily
KCV87_20305	COG1309	transcriptional regulator
KCV87_20335	COG1716	ATPase activity
KCV87_20340	COG1716	ATPase activity
KCV87_20355	COG0768	penicillin binding
KCV87_20360	COG0515	serine threonine protein kinase
KCV87_20365	COG0515	serine threonine protein kinase
KCV87_20365	COG2815	serine threonine protein kinase
KCV87_20385	COG3764	Sortase (surface protein transpeptidase)
KCV87_20400	COG0705	Rhomboid family
KCV87_20405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCV87_20420	COG2259	Doxx family
KCV87_20445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCV87_20455	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
KCV87_20460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCV87_20465	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KCV87_20470	COG0592	DNA-directed DNA polymerase activity
KCV87_20475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCV87_20480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KCV87_20485	COG0594	ribonuclease P activity
KCV87_20490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KCV87_20495	COG0706	membrane insertase activity
KCV87_20510	COG0357	Ribosomal RNA small subunit methyltransferase G
KCV87_20515	COG1192	Involved in chromosome partitioning
KCV87_20525	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCV87_20530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCV87_20540	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCV87_20540	COG3409	Peptidoglycan-binding domain 1 protein
KCV87_20545	COG0492	ferredoxin-NADP+ reductase activity
KCV87_20545	COG3118	belongs to the thioredoxin family
KCV87_20565	COG1595	DNA-templated transcription, initiation
KCV87_20570	COG0515	serine threonine protein kinase
KCV87_20590	COG0617	tRNA 3'-terminal CCA addition
KCV87_20595	COG2197	response regulator
KCV87_20615	COG0495	leucyl-tRNA aminoacylation
KCV87_20635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCV87_20640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCV87_20660	COG0583	DNA-binding transcription factor activity
KCV87_20670	COG1063	alcohol dehydrogenase
KCV87_20675	COG0702	epimerase
KCV87_20765	COG0305	Participates in initiation and elongation during chromosome replication
KCV87_20770	COG0359	binds to the 23S rRNA
KCV87_20775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCV87_20780	COG0629	single-stranded DNA binding
KCV87_20785	COG0360	Binds together with S18 to 16S ribosomal RNA
KCV87_20810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCV87_20830	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_20835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCV87_20840	COG2814	Major facilitator Superfamily
KCV87_20855	COG4221	oxidoreductase activity
KCV87_20860	COG0402	S-adenosylhomocysteine deaminase activity
KCV87_20875	COG1131	(ABC) transporter
KCV87_20895	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KCV87_20900	COG4585	Histidine kinase
KCV87_20915	COG0561	phosphatase activity
KCV87_20925	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_20930	COG2197	response regulator
KCV87_20935	COG4585	Histidine kinase
KCV87_20950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCV87_20975	COG1940	carbohydrate kinase activity
KCV87_21005	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KCV87_21040	COG0765	amino acid transport
KCV87_21045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCV87_21055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCV87_21065	COG0022	dehydrogenase e1 component
KCV87_21070	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCV87_21080	COG1309	transcriptional regulator
KCV87_21090	COG1960	acyl-CoA dehydrogenase activity
KCV87_21110	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_21145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCV87_21160	COG1960	acyl-CoA dehydrogenase activity
KCV87_21165	COG2197	response regulator
KCV87_21185	COG0717	Belongs to the dCTP deaminase family
KCV87_21210	COG1950	PFAM Membrane protein of
KCV87_21215	COG0247	lactate metabolic process
KCV87_21215	COG2181	nitrate reductase activity
KCV87_21235	COG0443	Heat shock 70 kDa protein
KCV87_21240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCV87_21245	COG0484	heat shock protein binding
KCV87_21250	COG0789	Transcriptional regulator
KCV87_21255	COG2871	sodium ion transport
KCV87_21265	COG0542	response to heat
KCV87_21275	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_21300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCV87_21330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCV87_21335	COG1072	(Pantothenic acid kinase))
KCV87_21340	COG0586	Pfam SNARE associated Golgi protein
KCV87_21345	COG0277	FAD linked oxidase domain protein
KCV87_21370	COG1595	DNA-templated transcription, initiation
KCV87_21380	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_21385	COG0667	Aldo Keto reductase
KCV87_21405	COG4129	membrane
KCV87_21435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCV87_21440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_21445	COG0584	glycerophosphoryl diester phosphodiesterase
KCV87_21490	COG0436	Aminotransferase
KCV87_21500	COG1011	Hydrolase
KCV87_21510	COG1595	DNA-templated transcription, initiation
KCV87_21525	COG1595	DNA-templated transcription, initiation
KCV87_21535	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCV87_21550	COG0765	amino acid transport
KCV87_21560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KCV87_21585	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCV87_21590	COG0047	phosphoribosylformylglycinamidine synthase activity
KCV87_21595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCV87_21620	COG5001	Diguanylate cyclase
KCV87_21620	COG3300	MHYT domain
KCV87_21625	COG1063	alcohol dehydrogenase
KCV87_21685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KCV87_21700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCV87_21715	COG1082	Xylose isomerase domain protein TIM barrel
KCV87_21725	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCV87_21730	COG1129	ABC transporter
KCV87_21740	COG3718	enzyme involved in inositol metabolism
KCV87_21745	COG3962	Belongs to the TPP enzyme family
KCV87_21790	COG0735	belongs to the Fur family
KCV87_21810	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KCV87_21815	COG4044	May play a role in the intracellular transport of hydrophobic ligands
KCV87_21855	COG0456	acetyltransferase
KCV87_21875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCV87_21895	COG1316	TRANSCRIPTIONal
KCV87_21955	COG2255	four-way junction helicase activity
KCV87_21975	COG1278	Cold shock
KCV87_22035	COG2364	Membrane
KCV87_22040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCV87_22075	COG1136	(ABC) transporter
KCV87_22105	COG2733	membrane
KCV87_22110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCV87_22135	COG0693	protein deglycase activity
KCV87_22150	COG3226	Transcriptional regulator
KCV87_22180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KCV87_22200	COG0438	transferase activity, transferring glycosyl groups
KCV87_22215	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_22220	COG0588	phosphoglycerate mutase activity
KCV87_22230	COG0667	Aldo Keto reductase
KCV87_22235	COG5002	protein histidine kinase activity
KCV87_22270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCV87_22310	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_22330	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCV87_22335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KCV87_22340	COG0181	hydroxymethylbilane synthase activity
KCV87_22350	COG0113	porphobilinogen synthase activity
KCV87_22390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCV87_22395	COG0406	alpha-ribazole phosphatase activity
KCV87_22415	COG0785	Cytochrome C biogenesis protein
KCV87_22425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KCV87_22475	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KCV87_22525	COG3396	Phenylacetate-CoA oxygenase
KCV87_22530	COG3460	Phenylacetate-CoA oxygenase
KCV87_22535	COG3396	Phenylacetate-CoA oxygenase
KCV87_22540	COG2151	metal-sulfur cluster biosynthetic enzyme
KCV87_22545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KCV87_22555	COG0483	inositol monophosphate 1-phosphatase activity
KCV87_22560	COG2226	methyltransferase
KCV87_22575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCV87_22580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCV87_22585	COG0649	NAD binding
KCV87_22595	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KCV87_22600	COG1034	ATP synthesis coupled electron transport
KCV87_22605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KCV87_22610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCV87_22620	COG0713	ATP synthesis coupled electron transport
KCV87_22635	COG1007	ATP synthesis coupled electron transport
KCV87_22640	COG0142	geranyltranstransferase activity
KCV87_22655	COG1013	pyruvate-flavodoxin oxidoreductase activity
KCV87_22660	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KCV87_22660	COG0674	pyruvate-flavodoxin oxidoreductase activity
KCV87_22670	COG1522	sequence-specific DNA binding
KCV87_22675	COG1834	amidinotransferase
KCV87_22690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCV87_22695	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCV87_22700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCV87_22710	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCV87_22715	COG1666	GTP binding
KCV87_22760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KCV87_22765	COG2030	dehydratase
KCV87_22770	COG2030	dehydratase
KCV87_22785	COG0436	Aminotransferase
KCV87_22795	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCV87_22805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCV87_22810	COG0081	regulation of translation
KCV87_22840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCV87_22865	COG0085	RNA polymerase activity
KCV87_22870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCV87_22905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCV87_22910	COG0049	tRNA binding
KCV87_22915	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCV87_22920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCV87_22925	COG0051	transcription antitermination factor activity, RNA binding
KCV87_22930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCV87_22935	COG0088	Forms part of the polypeptide exit tunnel
KCV87_22940	COG0089	rRNA binding
KCV87_22945	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCV87_22950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCV87_22955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCV87_22960	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCV87_22975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCV87_22980	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCV87_22985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCV87_22990	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCV87_22995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCV87_23000	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCV87_23010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCV87_23015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCV87_23035	COG0563	adenylate kinase activity
KCV87_23055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCV87_23060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KCV87_23070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCV87_23075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCV87_23080	COG0202	RNA polymerase activity
KCV87_23085	COG0203	ribosomal protein L17
KCV87_23090	COG0101	tRNA pseudouridine synthase activity
KCV87_23095	COG1404	Belongs to the peptidase S8 family
KCV87_23125	COG1404	Belongs to the peptidase S8 family
KCV87_23135	COG1674	ftsk spoiiie
KCV87_23145	COG0443	Heat shock 70 kDa protein
KCV87_23165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCV87_23170	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KCV87_23175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCV87_23200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCV87_23210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCV87_23230	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_23235	COG3118	belongs to the thioredoxin family
KCV87_23250	COG0456	acetyltransferase
KCV87_23255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCV87_23265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCV87_23270	COG0459	protein refolding
KCV87_23315	COG0516	GMP reductase activity
KCV87_23330	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_23340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCV87_23340	COG0519	Catalyzes the synthesis of GMP from XMP
KCV87_23370	COG0697	spore germination
KCV87_23375	COG0583	DNA-binding transcription factor activity
KCV87_23380	COG0515	serine threonine protein kinase
KCV87_23385	COG0515	serine threonine protein kinase
KCV87_23385	COG2815	serine threonine protein kinase
KCV87_23440	COG0045	succinate-CoA ligase (ADP-forming) activity
KCV87_23465	COG0138	bifunctional purine biosynthesis protein purh
KCV87_23485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCV87_23515	COG0039	L-malate dehydrogenase activity
KCV87_23540	COG4555	ABC transporter
KCV87_23565	COG0484	heat shock protein binding
KCV87_23600	COG0708	Exodeoxyribonuclease III
KCV87_23615	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KCV87_23625	COG0180	Tryptophanyl-tRNA synthetase
KCV87_23630	COG1295	ribonuclease BN
KCV87_23645	COG1686	Belongs to the peptidase S11 family
KCV87_23650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KCV87_23665	COG2009	succinate dehydrogenase
KCV87_23705	COG1744	ABC transporter substrate-binding protein PnrA-like
KCV87_23710	COG3845	ABC transporter
KCV87_23715	COG4603	Belongs to the binding-protein-dependent transport system permease family
KCV87_23720	COG1079	Belongs to the binding-protein-dependent transport system permease family
KCV87_23745	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCV87_23765	COG3883	PFAM NLP P60 protein
KCV87_23765	COG0791	NLP P60 protein
KCV87_23785	COG3629	intracellular signal transduction
KCV87_23785	COG3903	Transcriptional regulator
KCV87_23820	COG5635	Nacht domain
KCV87_23820	COG2319	Wd-40 repeat
KCV87_23840	COG3654	unkown
KCV87_23860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCV87_23870	COG0515	serine threonine protein kinase
KCV87_23870	COG2815	serine threonine protein kinase
KCV87_23900	COG1473	amidohydrolase
KCV87_23900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KCV87_23915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KCV87_23920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KCV87_23925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KCV87_23940	COG4585	Histidine kinase
KCV87_23945	COG2197	response regulator
KCV87_23990	COG4770	biotin carboxylase activity
KCV87_24000	COG1301	dicarboxylic acid transport
KCV87_24005	COG0424	maF-like protein
KCV87_24020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCV87_24035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCV87_24060	COG2205	protein histidine kinase activity
KCV87_24065	COG0745	RESPONSE REGULATOR receiver
KCV87_24070	COG0483	inositol monophosphate 1-phosphatase activity
KCV87_24110	COG2186	Transcriptional regulator
KCV87_24115	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KCV87_24140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KCV87_24155	COG0483	inositol monophosphate 1-phosphatase activity
KCV87_24175	COG2259	Doxx family
KCV87_24185	COG1316	TRANSCRIPTIONal
KCV87_24190	COG1316	TRANSCRIPTIONal
KCV87_24205	COG0297	glycogen (starch) synthase activity
KCV87_24225	COG0438	transferase activity, transferring glycosyl groups
KCV87_24245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCV87_24260	COG0778	Nitroreductase
KCV87_24260	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
KCV87_24265	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KCV87_24270	COG1994	Peptidase M50
KCV87_24310	COG1482	cell wall glycoprotein biosynthetic process
KCV87_24320	COG0531	amino acid
KCV87_24325	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KCV87_24340	COG0745	RESPONSE REGULATOR receiver
KCV87_24345	COG5002	protein histidine kinase activity
KCV87_24350	COG5401	PFAM Sporulation and spore germination
KCV87_24355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCV87_24360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCV87_24365	COG0653	protein targeting
KCV87_24375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCV87_24380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCV87_24405	COG1162	GTPase activity
KCV87_24410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KCV87_24415	COG2135	peptidase activity
KCV87_24425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCV87_24430	COG1595	DNA-templated transcription, initiation
KCV87_24435	COG5662	AntiSigma factor
KCV87_24450	COG1597	lipid kinase activity
KCV87_24470	COG0406	alpha-ribazole phosphatase activity
KCV87_24495	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KCV87_24505	COG5001	Diguanylate cyclase
KCV87_24545	COG1174	glycine betaine transport
KCV87_24565	COG2986	histidine ammonia-lyase
KCV87_24570	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCV87_24585	COG1228	amidohydrolase
KCV87_24600	COG3903	Transcriptional regulator
KCV87_24600	COG3629	intracellular signal transduction
KCV87_24615	COG0667	Aldo Keto reductase
KCV87_24630	COG0567	Dehydrogenase, E1 component
KCV87_24630	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCV87_24635	COG1132	(ABC) transporter
KCV87_24655	COG0686	Belongs to the AlaDH PNT family
KCV87_24660	COG0509	glycine decarboxylation via glycine cleavage system
KCV87_24665	COG1760	l-serine dehydratase
KCV87_24670	COG0386	Belongs to the glutathione peroxidase family
KCV87_24690	COG0673	inositol 2-dehydrogenase activity
KCV87_24700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCV87_24705	COG3469	chitinase activity
KCV87_24740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCV87_24750	COG1960	acyl-CoA dehydrogenase activity
KCV87_24760	COG1024	Enoyl-CoA hydratase
KCV87_24765	COG1960	acyl-CoA dehydrogenase activity
KCV87_24770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCV87_24785	COG3629	intracellular signal transduction
KCV87_24785	COG3903	Transcriptional regulator
KCV87_24815	COG0583	DNA-binding transcription factor activity
KCV87_24830	COG1404	Belongs to the peptidase S8 family
KCV87_24850	COG2205	protein histidine kinase activity
KCV87_24855	COG0745	RESPONSE REGULATOR receiver
KCV87_24860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KCV87_24875	COG1940	carbohydrate kinase activity
KCV87_24885	COG0640	Transcriptional regulator
KCV87_24915	COG3795	YCII-related domain
KCV87_24920	COG4941	Belongs to the sigma-70 factor family
KCV87_24925	COG2890	protein-(glutamine-N5) methyltransferase activity
KCV87_24935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_24950	COG4166	transmembrane transport
KCV87_24955	COG0601	transmembrane transport
KCV87_24960	COG0444	Belongs to the ABC transporter superfamily
KCV87_25005	COG1609	Transcriptional regulator
KCV87_25010	COG0667	Aldo Keto reductase
KCV87_25020	COG1162	GTPase activity
KCV87_25060	COG0596	Alpha beta hydrolase
KCV87_25065	COG3903	Transcriptional regulator
KCV87_25065	COG3629	intracellular signal transduction
KCV87_25095	COG1051	belongs to the nudix hydrolase family
KCV87_25095	COG1056	cytidyltransferase-related domain
KCV87_25125	COG3537	Alpha-1,2-mannosidase
KCV87_25140	COG0018	arginyl-trna synthetase
KCV87_25145	COG0019	diaminopimelate decarboxylase activity
KCV87_25150	COG0460	homoserine dehydrogenase
KCV87_25155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCV87_25160	COG0083	homoserine kinase activity
KCV87_25165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCV87_25175	COG0254	rRNA binding
KCV87_25180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCV87_25195	COG2890	protein-(glutamine-N5) methyltransferase activity
KCV87_25205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCV87_25220	COG0356	it plays a direct role in the translocation of protons across the membrane
KCV87_25225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCV87_25230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCV87_25235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCV87_25240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCV87_25245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCV87_25250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCV87_25255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KCV87_25290	COG1335	isochorismatase
KCV87_25295	COG1024	Enoyl-CoA hydratase
KCV87_25310	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KCV87_25360	COG2376	Dihydroxyacetone kinase
KCV87_25405	COG0346	lactoylglutathione lyase activity
KCV87_25410	COG0183	Belongs to the thiolase family
KCV87_25450	COG0596	Alpha beta hydrolase
KCV87_25460	COG1879	ABC-type sugar transport system periplasmic component
KCV87_25465	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCV87_25480	COG1609	Transcriptional regulator
KCV87_25490	COG1131	(ABC) transporter
KCV87_25495	COG2409	Drug exporters of the RND superfamily
KCV87_25505	COG1846	Transcriptional regulator
KCV87_25535	COG2321	neutral zinc metallopeptidase
KCV87_25540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCV87_25550	COG0366	Alpha amylase catalytic
KCV87_25555	COG0366	Alpha amylase catalytic
KCV87_25560	COG0058	SHG alpha-glucan phosphorylase activity
KCV87_25585	COG1119	ATPase activity
KCV87_25595	COG2226	methyltransferase
KCV87_25610	COG0110	maltose O-acetyltransferase activity
KCV87_25635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCV87_25655	COG1307	EDD domain protein, DegV family
KCV87_25665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KCV87_25690	COG0482	sulfurtransferase activity
KCV87_25710	COG2855	membrane
KCV87_25725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCV87_25740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCV87_25745	COG0154	amidase activity
KCV87_25790	COG2259	Doxx family
KCV87_25795	COG0129	dihydroxy-acid dehydratase activity
KCV87_25815	COG0440	acetolactate synthase activity
KCV87_25820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCV87_25835	COG1404	Belongs to the peptidase S8 family
KCV87_25840	COG0473	3-isopropylmalate dehydrogenase activity
KCV87_25845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCV87_25855	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCV87_25865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCV87_25895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCV87_25900	COG0066	3-isopropylmalate dehydratase activity
KCV87_25910	COG0494	nUDIX hydrolase
KCV87_25910	COG0406	alpha-ribazole phosphatase activity
KCV87_25925	COG1920	GTP binding
KCV87_25935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KCV87_25940	COG0626	cystathionine gamma-synthase activity
KCV87_25975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCV87_25990	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCV87_26015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KCV87_26020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCV87_26035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KCV87_26040	COG1461	Dihydroxyacetone kinase
KCV87_26045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCV87_26085	COG0742	ribosomal rna small subunit methyltransferase
KCV87_26090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCV87_26105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KCV87_26110	COG0571	ribonuclease III activity
KCV87_26120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCV87_26135	COG1252	NADH dehydrogenase
KCV87_26150	COG2340	Cysteine-rich secretory protein family
KCV87_26155	COG1254	Belongs to the acylphosphatase family
KCV87_26190	COG0454	-acetyltransferase
KCV87_26190	COG0456	acetyltransferase
KCV87_26200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KCV87_26220	COG1414	Transcriptional regulator
KCV87_26225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KCV87_26250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCV87_26255	COG4266	Belongs to the allantoicase family
KCV87_26275	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KCV87_26300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KCV87_26305	COG0228	four-way junction DNA binding
KCV87_26320	COG0336	Belongs to the RNA methyltransferase TrmD family
KCV87_26325	COG0335	large ribosomal subunit rRNA binding
KCV87_26330	COG0681	Belongs to the peptidase S26 family
KCV87_26335	COG0681	Belongs to the peptidase S26 family
KCV87_26340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCV87_26350	COG0792	nuclease activity
KCV87_26370	COG1191	sigma factor activity
KCV87_26380	COG0052	Belongs to the universal ribosomal protein uS2 family
KCV87_26385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCV87_26390	COG0528	UMP kinase activity
KCV87_26395	COG0233	cytoplasmic translational termination
KCV87_26415	COG0667	Aldo Keto reductase
KCV87_26425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KCV87_26435	COG0515	serine threonine protein kinase
KCV87_26445	COG3842	ATPase activity
KCV87_26455	COG1176	ABC-type spermidine putrescine transport system, permease component I
KCV87_26460	COG1177	transmembrane transport
KCV87_26465	COG4585	Histidine kinase
KCV87_26470	COG2197	response regulator
KCV87_26485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KCV87_26490	COG0750	zinc metalloprotease
KCV87_26495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KCV87_26520	COG1492	cobalamin metabolic process
KCV87_26535	COG2186	Transcriptional regulator
KCV87_26540	COG2807	transmembrane transport
KCV87_26550	COG1881	PFAM PEBP family protein
KCV87_26555	COG0726	polysaccharide deacetylase
KCV87_26560	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCV87_26570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KCV87_26575	COG0110	maltose O-acetyltransferase activity
KCV87_26585	COG0501	Belongs to the peptidase M48B family
KCV87_26600	COG1280	lysine exporter protein (LysE YggA)
KCV87_26615	COG0156	8-amino-7-oxononanoate synthase activity
KCV87_26665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCV87_26665	COG1648	precorrin-2 dehydrogenase activity
KCV87_26670	COG0513	Belongs to the DEAD box helicase family
KCV87_26685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCV87_26690	COG3022	response to hydroperoxide
KCV87_26700	COG0442	prolyl-tRNA aminoacylation
KCV87_26725	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_26750	COG0779	Required for maturation of 30S ribosomal subunits
KCV87_26780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KCV87_26795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCV87_26815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCV87_26820	COG1185	polyribonucleotide nucleotidyltransferase activity
KCV87_26830	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KCV87_26850	COG3214	Protein conserved in bacteria
KCV87_26855	COG0667	Aldo Keto reductase
KCV87_26860	COG1309	transcriptional regulator
KCV87_26875	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KCV87_26885	COG0515	serine threonine protein kinase
KCV87_26895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCV87_26900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCV87_26925	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KCV87_26930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KCV87_26940	COG1546	Belongs to the CinA family
KCV87_26940	COG1058	Belongs to the CinA family
KCV87_26945	COG1396	sequence-specific DNA binding
KCV87_26950	COG1842	Phage shock protein A
KCV87_26960	COG2233	PERMEase
KCV87_26965	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_26975	COG0167	dihydroorotate dehydrogenase activity
KCV87_26980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCV87_26985	COG1192	Involved in chromosome partitioning
KCV87_27000	COG0174	glutamine synthetase
KCV87_27010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCV87_27015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCV87_27045	COG0714	Associated with various cellular activities
KCV87_27050	COG2001	Belongs to the MraZ family
KCV87_27055	COG0275	rRNA processing
KCV87_27065	COG0768	penicillin binding
KCV87_27080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCV87_27085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCV87_27110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCV87_27115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KCV87_27120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KCV87_27125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCV87_27140	COG1799	cell septum assembly
KCV87_27160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCV87_27165	COG1872	DUF167
KCV87_27180	COG3263	regulation of cellular component size
KCV87_27190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCV87_27200	COG2814	Major facilitator Superfamily
KCV87_27215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCV87_27230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KCV87_27255	COG2814	Major facilitator Superfamily
KCV87_27285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KCV87_27310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCV87_27320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCV87_27325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCV87_27330	COG0131	Imidazoleglycerol-phosphate dehydratase
KCV87_27340	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KCV87_27350	COG3959	Transketolase, thiamine diphosphate binding domain
KCV87_27355	COG3958	Transketolase
KCV87_27365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCV87_27370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCV87_27385	COG3654	unkown
KCV87_27390	COG0107	imidazoleglycerol-phosphate synthase activity
KCV87_27400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCV87_27410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCV87_27420	COG0134	indole-3-glycerol-phosphate synthase activity
KCV87_27425	COG0133	tryptophan synthase activity
KCV87_27430	COG0159	tryptophan synthase activity
KCV87_27435	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCV87_27440	COG0745	RESPONSE REGULATOR receiver
KCV87_27450	COG2205	protein histidine kinase activity
KCV87_27460	COG1301	dicarboxylic acid transport
KCV87_27465	COG0070	glutamate synthase
KCV87_27465	COG0067	glutamate synthase
KCV87_27465	COG0069	glutamate synthase activity
KCV87_27500	COG1946	Acyl-CoA thioesterase
KCV87_27515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KCV87_27545	COG3903	Transcriptional regulator
KCV87_27545	COG3629	intracellular signal transduction
KCV87_27550	COG1672	PFAM Archaeal ATPase
KCV87_27550	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KCV87_27555	COG1136	(ABC) transporter
KCV87_27555	COG0577	efflux transmembrane transporter activity
KCV87_27560	COG0577	efflux transmembrane transporter activity
KCV87_27560	COG1136	(ABC) transporter
KCV87_27585	COG1024	Enoyl-CoA hydratase
KCV87_27585	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCV87_27590	COG0183	Belongs to the thiolase family
KCV87_27600	COG1960	acyl-CoA dehydrogenase activity
KCV87_27605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KCV87_27620	COG1566	PFAM secretion protein HlyD family protein
KCV87_27630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KCV87_27635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCV87_27640	COG0778	Nitroreductase
KCV87_27655	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KCV87_27665	COG1408	metallophosphoesterase
KCV87_27670	COG1595	DNA-templated transcription, initiation
KCV87_27690	COG1937	Protein conserved in bacteria
KCV87_27715	COG0514	ATP-dependent DNA helicase (RecQ)
KCV87_27720	COG1357	PFAM Pentapeptide repeats (8 copies)
KCV87_27735	COG0251	oxidation-reduction process
KCV87_27740	COG1832	CoA-binding protein
KCV87_27785	COG0410	ABC transporter
KCV87_27795	COG2050	protein possibly involved in aromatic compounds catabolism
KCV87_27805	COG0673	inositol 2-dehydrogenase activity
KCV87_27820	COG1309	transcriptional regulator
KCV87_27825	COG1511	domain protein
KCV87_27845	COG0539	negative regulation of cytoplasmic translation
KCV87_27855	COG0237	dephospho-CoA kinase activity
KCV87_27855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCV87_27885	COG1131	(ABC) transporter
KCV87_27895	COG4946	Tricorn protease homolog
KCV87_27895	COG1506	peptidase
KCV87_27895	COG0823	Involved in the tonB-independent uptake of proteins
KCV87_27925	COG5650	phosphatidylinositol metabolic process
KCV87_28000	COG0640	Transcriptional regulator
KCV87_28005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCV87_28025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCV87_28040	COG2610	gluconate transmembrane transporter activity
KCV87_28045	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
KCV87_28070	COG3629	intracellular signal transduction
KCV87_28070	COG3903	Transcriptional regulator
KCV87_28085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCV87_28090	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KCV87_28095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCV87_28100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCV87_28105	COG0642	Histidine kinase
KCV87_28110	COG0745	RESPONSE REGULATOR receiver
KCV87_28120	COG0326	Molecular chaperone. Has ATPase activity
KCV87_28125	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCV87_28130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCV87_28130	COG0072	phenylalanine-tRNA ligase activity
KCV87_28150	COG1476	TRANSCRIPTIONal
KCV87_28160	COG0604	alcohol dehydrogenase
KCV87_28165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCV87_28170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCV87_28175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KCV87_28190	COG1438	arginine binding
KCV87_28195	COG0137	argininosuccinate synthase activity
KCV87_28200	COG0165	Argininosuccinate lyase
KCV87_28205	COG2094	Belongs to the DNA glycosylase MPG family
KCV87_28220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCV87_28245	COG0647	UMP catabolic process
KCV87_28260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCV87_28285	COG0504	CTP synthase activity
KCV87_28290	COG0494	nUDIX hydrolase
KCV87_28310	COG0640	Transcriptional regulator
KCV87_28325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCV87_28330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCV87_28335	COG1187	pseudouridine synthase activity
KCV87_28345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCV87_28350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCV87_28355	COG1116	anion transmembrane transporter activity
KCV87_28355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCV87_28365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCV87_28375	COG2018	Roadblock/LC7 domain
KCV87_28425	COG4977	sequence-specific DNA binding
KCV87_28445	COG1366	Belongs to the anti-sigma-factor antagonist family
KCV87_28450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KCV87_28495	COG1222	aaa ATPase
KCV87_28580	COG2197	response regulator
KCV87_28585	COG2197	response regulator
KCV87_28630	COG0667	Aldo Keto reductase
KCV87_28685	COG1716	ATPase activity
KCV87_28705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCV87_28705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCV87_28750	COG1609	Transcriptional regulator
KCV87_28800	COG0564	pseudouridine synthase activity
KCV87_28805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCV87_28830	COG1132	(ABC) transporter
KCV87_28840	COG2755	lipolytic protein G-D-S-L family
KCV87_28840	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KCV87_28845	COG3629	intracellular signal transduction
KCV87_28845	COG3903	Transcriptional regulator
KCV87_28860	COG2030	dehydratase
KCV87_28860	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_28875	COG0667	Aldo Keto reductase
KCV87_28880	COG2258	MOSC domain
KCV87_28905	COG1024	Enoyl-CoA hydratase
KCV87_28925	COG0395	ABC-type sugar transport system, permease component
KCV87_28990	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KCV87_29010	COG1733	regulation of RNA biosynthetic process
KCV87_29030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KCV87_29060	COG3275	phosphorelay sensor kinase activity
KCV87_29065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCV87_29075	COG3279	Response regulator of the LytR AlgR family
KCV87_29085	COG1388	LysM domain
KCV87_29095	COG4581	dead DEAH box helicase
KCV87_29135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCV87_29140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCV87_29150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCV87_29155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCV87_29160	COG1263	PTS System
KCV87_29165	COG2188	Transcriptional regulator
KCV87_29170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCV87_29175	COG2190	(PTS) system
KCV87_29185	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCV87_29190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCV87_29200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCV87_29205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCV87_29215	COG0006	proline dipeptidase activity
KCV87_29220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCV87_29225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCV87_29235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCV87_29240	COG0540	Belongs to the ATCase OTCase family
KCV87_29255	COG0505	Belongs to the CarA family
KCV87_29265	COG0284	orotidine-5'-phosphate decarboxylase activity
KCV87_29275	COG0194	GDP metabolic process
KCV87_29280	COG1758	RNA polymerase activity
KCV87_29290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCV87_29305	COG0405	Gamma-glutamyltransferase
KCV87_29330	COG0242	peptide deformylase activity
KCV87_29335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCV87_29365	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCV87_29365	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCV87_29370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KCV87_29380	COG2234	aminopeptidase activity
KCV87_29430	COG0322	excinuclease ABC activity
KCV87_29435	COG1660	Displays ATPase and GTPase activities
KCV87_29445	COG1481	regulation of sporulation
KCV87_29460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KCV87_29465	COG0126	phosphoglycerate kinase activity
KCV87_29470	COG0149	triose-phosphate isomerase activity
KCV87_29475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCV87_29495	COG4585	Histidine kinase
KCV87_29500	COG0363	glucosamine-6-phosphate deaminase activity
KCV87_29515	COG0166	Belongs to the GPI family
KCV87_29520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCV87_29530	COG0109	protoheme IX farnesyltransferase activity
KCV87_29585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCV87_29595	COG5002	protein histidine kinase activity
KCV87_29600	COG2018	Roadblock/LC7 domain
KCV87_29610	COG1510	regulation of RNA biosynthetic process
KCV87_29645	COG1131	(ABC) transporter
KCV87_29655	COG0438	transferase activity, transferring glycosyl groups
KCV87_29660	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCV87_29700	COG0396	ATPase activity
KCV87_29710	COG0822	iron-sulfur transferase activity
KCV87_29715	COG2151	metal-sulfur cluster biosynthetic enzyme
KCV87_29730	COG3706	GGDEF domain
KCV87_29760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KCV87_29795	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_29800	COG0488	(ABC) transporter
KCV87_29810	COG1024	Enoyl-CoA hydratase
KCV87_29815	COG1132	(ABC) transporter
KCV87_29820	COG4821	SIS domain
KCV87_29825	COG1349	DNA-binding transcription factor activity
KCV87_29835	COG0583	DNA-binding transcription factor activity
KCV87_29850	COG0596	Alpha beta hydrolase
KCV87_29860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCV87_29865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCV87_29870	COG0739	heme binding
KCV87_29885	COG1609	Transcriptional regulator
KCV87_29945	COG1309	transcriptional regulator
KCV87_29950	COG0300	oxidoreductase activity
KCV87_29955	COG1619	proteins homologs of microcin C7 resistance protein MccF
KCV87_29960	COG1609	Transcriptional regulator
KCV87_29975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_29995	COG0248	Ppx GppA phosphatase
KCV87_30010	COG5002	protein histidine kinase activity
KCV87_30010	COG0784	Response regulator, receiver
KCV87_30015	COG2208	phosphoserine phosphatase activity
KCV87_30015	COG2770	Histidine kinase
KCV87_30030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCV87_30035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KCV87_30040	COG3485	protocatechuate 3,4-dioxygenase
KCV87_30045	COG3485	protocatechuate 3,4-dioxygenase
KCV87_30050	COG2267	carboxylic ester hydrolase activity
KCV87_30055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCV87_30060	COG1414	Transcriptional regulator
KCV87_30110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCV87_30115	COG1132	(ABC) transporter
KCV87_30120	COG1132	(ABC) transporter
KCV87_30125	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KCV87_30130	COG4607	ABC-type enterochelin transport system periplasmic component
KCV87_30165	COG0246	Mannitol dehydrogenase
KCV87_30170	COG0477	Major facilitator Superfamily
KCV87_30175	COG1063	alcohol dehydrogenase
KCV87_30185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_30190	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_30195	COG1120	ATPase activity
KCV87_30200	COG3973	AAA domain
KCV87_30220	COG0823	Involved in the tonB-independent uptake of proteins
KCV87_30230	COG0300	oxidoreductase activity
KCV87_30235	COG1309	transcriptional regulator
KCV87_30250	COG3973	AAA domain
KCV87_30285	COG0784	Response regulator, receiver
KCV87_30290	COG4251	negative regulation of phosphorylation
KCV87_30305	COG2855	membrane
KCV87_30315	COG1309	transcriptional regulator
KCV87_30320	COG1064	alcohol dehydrogenase
KCV87_30330	COG0463	Glycosyl transferase, family 2
KCV87_30350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCV87_30360	COG0142	geranyltranstransferase activity
KCV87_30365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCV87_30370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCV87_30420	COG2205	protein histidine kinase activity
KCV87_30425	COG2340	Cysteine-rich secretory protein family
KCV87_30430	COG1522	sequence-specific DNA binding
KCV87_30445	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCV87_30450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCV87_30495	COG0009	L-threonylcarbamoyladenylate synthase
KCV87_30525	COG1253	flavin adenine dinucleotide binding
KCV87_30545	COG2409	Drug exporters of the RND superfamily
KCV87_30565	COG0500	methyltransferase
KCV87_30580	COG3693	PFAM glycoside hydrolase, family 10
KCV87_30585	COG2267	carboxylic ester hydrolase activity
KCV87_30600	COG1472	Belongs to the glycosyl hydrolase 3 family
KCV87_30625	COG0438	transferase activity, transferring glycosyl groups
KCV87_30635	COG0463	Glycosyl transferase, family 2
KCV87_30680	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KCV87_30700	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KCV87_30715	COG0583	DNA-binding transcription factor activity
KCV87_30725	COG0477	Major facilitator Superfamily
KCV87_30740	COG0745	RESPONSE REGULATOR receiver
KCV87_30745	COG2205	protein histidine kinase activity
KCV87_30755	COG1929	Belongs to the glycerate kinase type-1 family
KCV87_30785	COG3835	regulator
KCV87_30790	COG2755	lipolytic protein G-D-S-L family
KCV87_30800	COG2365	Tyrosine phosphatase family
KCV87_30810	COG2770	Histidine kinase
KCV87_30810	COG2208	phosphoserine phosphatase activity
KCV87_30825	COG2022	thiamine diphosphate biosynthetic process
KCV87_30850	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_30860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_30880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_30885	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_30895	COG1802	Transcriptional regulator
KCV87_30930	COG1902	pentaerythritol trinitrate reductase activity
KCV87_30945	COG0583	DNA-binding transcription factor activity
KCV87_30955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCV87_30965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCV87_30975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCV87_30990	COG1414	Transcriptional regulator
KCV87_31000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCV87_31010	COG0494	nUDIX hydrolase
KCV87_31015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCV87_31045	COG1472	Belongs to the glycosyl hydrolase 3 family
KCV87_31075	COG2072	flavoprotein involved in K transport
KCV87_31080	COG3386	PFAM SMP-30 Gluconolaconase
KCV87_31095	COG1309	transcriptional regulator
KCV87_31100	COG1132	(ABC) transporter
KCV87_31105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCV87_31110	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_31120	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_31125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCV87_31130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_31150	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_31155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KCV87_31170	COG0515	serine threonine protein kinase
KCV87_31180	COG1819	glycosyl
KCV87_31195	COG1819	glycosyl
KCV87_31210	COG0702	epimerase
KCV87_31220	COG1216	Glycosyl transferase, family 2
KCV87_31230	COG2124	cytochrome p450
KCV87_31270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCV87_31290	COG1929	Belongs to the glycerate kinase type-1 family
KCV87_31305	COG0673	inositol 2-dehydrogenase activity
KCV87_31320	COG2018	Roadblock/LC7 domain
KCV87_31370	COG1309	transcriptional regulator
KCV87_31375	COG0477	Major facilitator Superfamily
KCV87_31395	COG2391	methyltransferase activity
KCV87_31400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCV87_31405	COG1309	transcriptional regulator
KCV87_31415	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_31420	COG0583	DNA-binding transcription factor activity
KCV87_31435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCV87_31455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_31460	COG1120	ATPase activity
KCV87_31510	COG0523	cobalamin synthesis protein
KCV87_31520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCV87_31525	COG1121	(ABC) transporter
KCV87_31560	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KCV87_31580	COG0443	Heat shock 70 kDa protein
KCV87_31685	COG1595	DNA-templated transcription, initiation
KCV87_31695	COG1131	(ABC) transporter
KCV87_31730	COG0402	S-adenosylhomocysteine deaminase activity
KCV87_31740	COG1609	Transcriptional regulator
KCV87_31745	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCV87_31755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KCV87_31770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCV87_31775	COG3938	Belongs to the proline racemase family
KCV87_31785	COG1802	Transcriptional regulator
KCV87_31790	COG0747	negative chemotaxis
KCV87_31820	COG0006	proline dipeptidase activity
KCV87_31855	COG1733	regulation of RNA biosynthetic process
KCV87_31870	COG0702	epimerase
KCV87_31965	COG1012	belongs to the aldehyde dehydrogenase family
KCV87_31970	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_31975	COG1309	transcriptional regulator
KCV87_32020	COG2755	lipolytic protein G-D-S-L family
KCV87_32035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_32070	COG2755	lipolytic protein G-D-S-L family
KCV87_32105	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCV87_32320	COG4974	Belongs to the 'phage' integrase family
KCV87_32350	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_32370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCV87_32375	COG0022	dehydrogenase e1 component
KCV87_32375	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCV87_32380	COG0657	acetylesterase activity
KCV87_32390	COG1022	Amp-dependent synthetase and ligase
KCV87_32430	COG0438	transferase activity, transferring glycosyl groups
KCV87_32455	COG3321	synthase
KCV87_32455	COG4221	oxidoreductase activity
KCV87_32455	COG0604	alcohol dehydrogenase
KCV87_32455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_32460	COG2909	trisaccharide binding
KCV87_32470	COG3250	beta-galactosidase activity
KCV87_32475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCV87_32480	COG0583	DNA-binding transcription factor activity
KCV87_32495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCV87_32525	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_32540	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_32575	COG1472	Belongs to the glycosyl hydrolase 3 family
KCV87_32580	COG0395	ABC-type sugar transport system, permease component
KCV87_32585	COG1175	transmembrane transport
KCV87_32595	COG1609	Transcriptional regulator
KCV87_32605	COG2272	Belongs to the type-B carboxylesterase lipase family
KCV87_32615	COG3321	synthase
KCV87_32615	COG0604	alcohol dehydrogenase
KCV87_32620	COG0300	oxidoreductase activity
KCV87_32640	COG2124	cytochrome p450
KCV87_32650	COG3629	intracellular signal transduction
KCV87_32650	COG3903	Transcriptional regulator
KCV87_32690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_32725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCV87_32725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCV87_32805	COG1278	Cold shock
KCV87_32830	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KCV87_32865	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KCV87_32875	COG2124	cytochrome p450
KCV87_32915	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_32915	COG0300	oxidoreductase activity
KCV87_32915	COG3321	synthase
KCV87_32915	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_32915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_33040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCV87_33095	COG3209	COG3209 Rhs family protein
KCV87_33150	COG0745	RESPONSE REGULATOR receiver
KCV87_33155	COG2205	protein histidine kinase activity
KCV87_33165	COG2197	response regulator
KCV87_33175	COG2409	Drug exporters of the RND superfamily
KCV87_33180	COG3973	AAA domain
KCV87_33215	COG0165	Argininosuccinate lyase
KCV87_33220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCV87_33225	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KCV87_33275	COG2808	Putative FMN-binding domain
KCV87_33280	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KCV87_33285	COG0644	oxidoreductase
KCV87_33295	COG1509	lysine 2,3-aminomutase activity
KCV87_33325	COG1063	alcohol dehydrogenase
KCV87_33355	COG0778	Nitroreductase
KCV87_33360	COG1309	transcriptional regulator
KCV87_33375	COG1022	Amp-dependent synthetase and ligase
KCV87_33420	COG4221	oxidoreductase activity
KCV87_33435	COG0730	response to heat
KCV87_33460	COG3629	intracellular signal transduction
KCV87_33490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCV87_33500	COG0604	alcohol dehydrogenase
KCV87_33500	COG3321	synthase
KCV87_33555	COG0604	alcohol dehydrogenase
KCV87_33555	COG3321	synthase
KCV87_33555	COG0604	alcohol dehydrogenase
KCV87_33555	COG3321	synthase
KCV87_33560	COG3321	synthase
KCV87_33560	COG0604	alcohol dehydrogenase
KCV87_33565	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCV87_33570	COG1121	(ABC) transporter
KCV87_33575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCV87_33590	COG4585	Histidine kinase
KCV87_33595	COG2197	response regulator
KCV87_33635	COG0604	alcohol dehydrogenase
KCV87_33645	COG0604	alcohol dehydrogenase
KCV87_33665	COG2258	MOSC domain
KCV87_33670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCV87_33670	COG0519	Catalyzes the synthesis of GMP from XMP
KCV87_33675	COG0753	catalase activity
KCV87_33685	COG0254	rRNA binding
KCV87_33720	COG0438	transferase activity, transferring glycosyl groups
KCV87_33735	COG3831	ATPase activity
KCV87_33760	COG1309	transcriptional regulator
KCV87_33765	COG1028	Short-chain dehydrogenase reductase Sdr
KCV87_33780	COG1309	transcriptional regulator
KCV87_33795	COG2340	Cysteine-rich secretory protein family
KCV87_33825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCV87_33840	COG2175	clavaminate synthase activity
KCV87_33850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCV87_33855	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KCV87_33860	COG0142	geranyltranstransferase activity
KCV87_33865	COG0556	nucleotide-excision repair
KCV87_33880	COG1201	RNA secondary structure unwinding
KCV87_33890	COG2080	2 iron, 2 sulfur cluster binding
KCV87_33895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KCV87_33895	COG2010	Cytochrome c
KCV87_33915	COG1024	Enoyl-CoA hydratase
KCV87_33915	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCV87_33920	COG0183	Belongs to the thiolase family
KCV87_33935	COG1960	acyl-CoA dehydrogenase activity
KCV87_33950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_33955	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KCV87_33985	COG3321	synthase
KCV87_33985	COG0604	alcohol dehydrogenase
KCV87_34005	COG2986	histidine ammonia-lyase
KCV87_34055	COG2814	Major facilitator Superfamily
KCV87_34070	COG0475	glutathione-regulated potassium exporter activity
KCV87_34080	COG2807	transmembrane transport
KCV87_34090	COG1309	transcriptional regulator
KCV87_34095	COG0861	Integral membrane protein TerC family
KCV87_34105	COG1522	sequence-specific DNA binding
KCV87_34125	COG0784	Response regulator, receiver
KCV87_34170	COG4172	Belongs to the ABC transporter superfamily
KCV87_34200	COG0243	molybdopterin cofactor binding
KCV87_34225	COG1960	acyl-CoA dehydrogenase activity
KCV87_34230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCV87_34235	COG0583	DNA-binding transcription factor activity
KCV87_34255	COG0277	FAD linked oxidase domain protein
KCV87_34295	COG1982	Orn Lys Arg decarboxylase major
KCV87_34320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_34325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCV87_34330	COG1120	ATPase activity
KCV87_34335	COG0596	Alpha beta hydrolase
KCV87_34350	COG2837	iron assimilation
KCV87_34360	COG0672	)-iron permease
KCV87_34365	COG0640	Transcriptional regulator
KCV87_34380	COG0640	Transcriptional regulator
KCV87_34395	COG0534	Mate efflux family protein
KCV87_34470	COG3831	ATPase activity
KCV87_34485	COG3850	Histidine kinase
KCV87_34490	COG2197	response regulator
KCV87_34495	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCV87_34510	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCV87_34525	COG0110	maltose O-acetyltransferase activity
KCV87_34575	COG0300	oxidoreductase activity
KCV87_34595	COG0667	Aldo Keto reductase
KCV87_34605	COG2182	Extracellular solute-binding protein
KCV87_34610	COG1175	transmembrane transport
KCV87_34615	COG0395	ABC-type sugar transport system, permease component
KCV87_34620	COG0439	Biotin carboxylase
KCV87_34625	COG0726	polysaccharide deacetylase
KCV87_34635	COG2124	cytochrome p450
KCV87_34640	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KCV87_34645	COG3467	pyridoxamine 5'-phosphate
KCV87_34685	COG2255	four-way junction helicase activity
KCV87_34700	COG0659	secondary active sulfate transmembrane transporter activity
KCV87_34710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCV87_34760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_34770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCV87_34780	COG0644	oxidoreductase
KCV87_34785	COG0697	spore germination
KCV87_34795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCV87_34795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCV87_34805	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KCV87_34815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCV87_34820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCV87_34855	COG4932	domain protein
KCV87_34855	COG3266	domain, Protein
KCV87_34855	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
KCV87_34860	COG1404	Belongs to the peptidase S8 family
KCV87_34865	COG1404	Belongs to the peptidase S8 family
KCV87_34870	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KCV87_34900	COG4221	oxidoreductase activity
KCV87_34910	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KCV87_34920	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KCV87_34925	COG3629	intracellular signal transduction
KCV87_34925	COG3903	Transcriptional regulator
KCV87_34950	COG0604	alcohol dehydrogenase
KCV87_34950	COG3321	synthase
KCV87_34980	COG3340	Belongs to the peptidase S51 family
KCV87_35015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCV87_35020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KCV87_35025	COG1414	Transcriptional regulator
KCV87_35045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KCV87_35055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCV87_35105	COG2267	carboxylic ester hydrolase activity
KCV87_35145	COG0745	RESPONSE REGULATOR receiver
KCV87_35150	COG2205	protein histidine kinase activity
KCV87_35175	COG4948	Mandelate Racemase Muconate Lactonizing
KCV87_35185	COG1609	Transcriptional regulator
KCV87_35195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCV87_35240	COG4977	sequence-specific DNA binding
KCV87_35240	COG1917	Cupin 2, conserved barrel domain protein
KCV87_35255	COG1024	Enoyl-CoA hydratase
KCV87_35260	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_35315	COG2207	Transcriptional regulator
KCV87_35325	COG2124	cytochrome p450
KCV87_35335	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KCV87_35340	COG0300	oxidoreductase activity
KCV87_35350	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KCV87_35375	COG0596	Alpha beta hydrolase
KCV87_35405	COG2814	Major facilitator Superfamily
KCV87_35415	COG1960	acyl-CoA dehydrogenase activity
KCV87_35450	COG2345	Transcriptional regulator
KCV87_35475	COG0577	efflux transmembrane transporter activity
KCV87_35480	COG1136	(ABC) transporter
KCV87_35480	COG0577	efflux transmembrane transporter activity
KCV87_35490	COG0745	RESPONSE REGULATOR receiver
KCV87_35495	COG5002	protein histidine kinase activity
KCV87_35505	COG1309	transcriptional regulator
KCV87_35515	COG3284	Transcriptional regulator
KCV87_35560	COG3851	Histidine kinase
KCV87_35565	COG2197	response regulator
KCV87_35575	COG1136	(ABC) transporter
KCV87_35630	COG0475	glutathione-regulated potassium exporter activity
KCV87_35645	COG0492	ferredoxin-NADP+ reductase activity
KCV87_35650	COG0318	PFAM AMP-dependent synthetase and ligase
KCV87_35670	COG0515	serine threonine protein kinase
KCV87_35700	COG1472	Belongs to the glycosyl hydrolase 3 family